locus-tag	class	description
D5R55_RS00015	COG0592	DNA-directed DNA polymerase activity
D5R55_RS00040	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
D5R55_RS00075	COG3038	cytochrome b561
D5R55_RS00080	COG0753	catalase activity
D5R55_RS00120	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D5R55_RS00125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D5R55_RS00130	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
D5R55_RS00175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D5R55_RS00195	COG1987	bacterial-type flagellum assembly
D5R55_RS00210	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D5R55_RS00225	COG1346	cytolysis
D5R55_RS00230	COG1380	Effector of murein hydrolase LrgA
D5R55_RS00235	COG0583	DNA-binding transcription factor activity
D5R55_RS00240	COG2814	Major facilitator Superfamily
D5R55_RS00245	COG1846	Transcriptional regulator
D5R55_RS00290	COG2165	general secretion pathway protein
D5R55_RS00305	COG1459	type II secretion system
D5R55_RS00325	COG0523	cobalamin synthesis protein
D5R55_RS00365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D5R55_RS00365	COG0519	Catalyzes the synthesis of GMP from XMP
D5R55_RS00370	COG1902	pentaerythritol trinitrate reductase activity
D5R55_RS00380	COG0642	Histidine kinase
D5R55_RS00400	COG3186	Phenylalanine-4-hydroxylase
D5R55_RS00405	COG1522	sequence-specific DNA binding
D5R55_RS00415	COG0583	DNA-binding transcription factor activity
D5R55_RS00420	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
D5R55_RS00475	COG0445	tRNA wobble uridine modification
D5R55_RS00485	COG1192	Involved in chromosome partitioning
D5R55_RS00490	COG1475	DNA binding
D5R55_RS00495	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D5R55_RS00510	COG0356	it plays a direct role in the translocation of protons across the membrane
D5R55_RS00535	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D5R55_RS00550	COG0318	PFAM AMP-dependent synthetase and ligase
D5R55_RS00565	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D5R55_RS00570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D5R55_RS00575	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D5R55_RS00575	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D5R55_RS00575	COG0506	proline dehydrogenase activity
D5R55_RS00580	COG0683	leucine binding
D5R55_RS00620	COG0640	Transcriptional regulator
D5R55_RS00635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D5R55_RS00640	COG0798	PFAM Bile acid sodium symporter
D5R55_RS00655	COG0431	NADPH-dependent FMN reductase
D5R55_RS00680	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS00690	COG0436	Aminotransferase
D5R55_RS00695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS00700	COG0277	FAD linked oxidase domain protein
D5R55_RS00710	COG0789	Transcriptional regulator
D5R55_RS00730	COG0668	transmembrane transport
D5R55_RS00735	COG0531	amino acid
D5R55_RS00740	COG4303	Ethanolamine ammonia lyase large subunit
D5R55_RS00750	COG0583	DNA-binding transcription factor activity
D5R55_RS00765	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS00785	COG0028	Belongs to the TPP enzyme family
D5R55_RS00800	COG1760	l-serine dehydratase
D5R55_RS00830	COG0673	inositol 2-dehydrogenase activity
D5R55_RS00835	COG0210	DNA helicase
D5R55_RS00885	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D5R55_RS00905	COG0519	Catalyzes the synthesis of GMP from XMP
D5R55_RS00920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D5R55_RS00925	COG2916	Histone family protein nucleoid-structuring protein H-NS
D5R55_RS00930	COG0438	transferase activity, transferring glycosyl groups
D5R55_RS00955	COG1360	Flagellar Motor Protein
D5R55_RS00960	COG0745	RESPONSE REGULATOR receiver
D5R55_RS00965	COG2198	Histidine kinase
D5R55_RS00965	COG0643	Histidine kinase
D5R55_RS00975	COG0840	transmembrane signaling receptor activity
D5R55_RS00980	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D5R55_RS00995	COG0745	RESPONSE REGULATOR receiver
D5R55_RS01000	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
D5R55_RS01020	COG3152	Membrane
D5R55_RS01025	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D5R55_RS01030	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D5R55_RS01045	COG1191	sigma factor activity
D5R55_RS01055	COG1950	PFAM Membrane protein of
D5R55_RS01060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D5R55_RS01110	COG1522	sequence-specific DNA binding
D5R55_RS01120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D5R55_RS01145	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D5R55_RS01150	COG2823	Periplasmic or secreted lipoprotein
D5R55_RS01230	COG2271	Major facilitator Superfamily
D5R55_RS01255	COG0577	efflux transmembrane transporter activity
D5R55_RS01265	COG0577	efflux transmembrane transporter activity
D5R55_RS01265	COG1136	(ABC) transporter
D5R55_RS01285	COG2084	Dehydrogenase
D5R55_RS01290	COG1280	lysine exporter protein (LysE YggA)
D5R55_RS01295	COG2814	Major facilitator Superfamily
D5R55_RS01300	COG0583	DNA-binding transcription factor activity
D5R55_RS01320	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D5R55_RS01330	COG1881	PFAM PEBP family protein
D5R55_RS01335	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D5R55_RS01340	COG0281	malic enzyme
D5R55_RS01340	COG0280	phosphate acetyltransferase
D5R55_RS01360	COG1522	sequence-specific DNA binding
D5R55_RS01380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D5R55_RS01385	COG2151	metal-sulfur cluster biosynthetic enzyme
D5R55_RS01390	COG3396	Phenylacetate-CoA oxygenase
D5R55_RS01395	COG3460	Phenylacetate-CoA oxygenase
D5R55_RS01400	COG3396	Phenylacetate-CoA oxygenase
D5R55_RS01465	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D5R55_RS01480	COG0081	regulation of translation
D5R55_RS01505	COG0514	ATP-dependent DNA helicase (RecQ)
D5R55_RS01635	COG0200	Binds to the 23S rRNA
D5R55_RS01640	COG0201	protein transport
D5R55_RS01685	COG4232	protein-disulfide reductase activity
D5R55_RS01705	COG1333	cytochrome c biogenesis protein
D5R55_RS01710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D5R55_RS01715	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D5R55_RS01720	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
D5R55_RS01770	COG0232	Belongs to the dGTPase family. Type 2 subfamily
D5R55_RS01775	COG1653	transport
D5R55_RS01785	COG0395	ABC-type sugar transport system, permease component
D5R55_RS01795	COG0584	glycerophosphoryl diester phosphodiesterase
D5R55_RS01815	COG0067	glutamate synthase
D5R55_RS01815	COG0070	glutamate synthase
D5R55_RS01815	COG0069	glutamate synthase activity
D5R55_RS01835	COG2814	Major facilitator Superfamily
D5R55_RS01845	COG4178	(ABC) transporter
D5R55_RS01875	COG1127	ABC transporter
D5R55_RS01880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D5R55_RS01885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D5R55_RS01905	COG1131	(ABC) transporter
D5R55_RS01910	COG0842	Transport permease protein
D5R55_RS01945	COG2095	MarC family integral membrane protein
D5R55_RS01995	COG0805	protein transport
D5R55_RS02000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D5R55_RS02005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D5R55_RS02010	COG0723	plastoquinol--plastocyanin reductase activity
D5R55_RS02015	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D5R55_RS02020	COG2857	Cytochrome c1
D5R55_RS02025	COG0625	glutathione transferase activity
D5R55_RS02030	COG2969	positive regulation of protein catabolic process
D5R55_RS02070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS02280	COG3422	double-strand break repair
D5R55_RS02300	COG1309	transcriptional regulator
D5R55_RS02315	COG0443	Heat shock 70 kDa protein
D5R55_RS02320	COG1278	Cold shock
D5R55_RS02330	COG0531	amino acid
D5R55_RS02335	COG3384	dioxygenase
D5R55_RS02345	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D5R55_RS02350	COG2890	protein-(glutamine-N5) methyltransferase activity
D5R55_RS02365	COG0745	RESPONSE REGULATOR receiver
D5R55_RS02375	COG0006	proline dipeptidase activity
D5R55_RS02380	COG1335	isochorismatase
D5R55_RS02390	COG0488	(ABC) transporter
D5R55_RS02400	COG0583	DNA-binding transcription factor activity
D5R55_RS02445	COG0012	GTP binding
D5R55_RS02450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D5R55_RS02455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D5R55_RS02470	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D5R55_RS02490	COG0512	Glutamine amidotransferase of anthranilate synthase
D5R55_RS02500	COG0546	phosphoglycolate phosphatase activity
D5R55_RS02505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D5R55_RS02510	COG2967	ApaG domain
D5R55_RS02515	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
D5R55_RS02525	COG2050	protein possibly involved in aromatic compounds catabolism
D5R55_RS02530	COG1024	Enoyl-CoA hydratase
D5R55_RS02535	COG0183	Belongs to the thiolase family
D5R55_RS02545	COG1024	Enoyl-CoA hydratase
D5R55_RS02580	COG0243	molybdopterin cofactor binding
D5R55_RS02585	COG0318	PFAM AMP-dependent synthetase and ligase
D5R55_RS02590	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS02600	COG2001	Belongs to the MraZ family
D5R55_RS02610	COG3116	cell division
D5R55_RS02620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D5R55_RS02625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D5R55_RS02655	COG1181	Belongs to the D-alanine--D-alanine ligase family
D5R55_RS02660	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D5R55_RS02675	COG0678	peroxiredoxin activity
D5R55_RS02680	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
D5R55_RS02710	COG0494	nUDIX hydrolase
D5R55_RS02715	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
D5R55_RS02730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D5R55_RS02745	COG4536	flavin adenine dinucleotide binding
D5R55_RS02875	COG0142	geranyltranstransferase activity
D5R55_RS02920	COG2095	MarC family integral membrane protein
D5R55_RS02925	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D5R55_RS02930	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D5R55_RS02985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D5R55_RS02990	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D5R55_RS03005	COG0439	Biotin carboxylase
D5R55_RS03015	COG0511	ligase activity, forming carbon-carbon bonds
D5R55_RS03020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D5R55_RS03025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D5R55_RS03035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D5R55_RS03040	COG3150	esterase
D5R55_RS03045	COG0557	exoribonuclease II activity
D5R55_RS03050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D5R55_RS03075	COG1414	Transcriptional regulator
D5R55_RS03080	COG3734	2-keto-3-deoxy-galactonokinase
D5R55_RS03085	COG0800	Aldolase
D5R55_RS03090	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS03105	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5R55_RS03120	COG0284	orotidine-5'-phosphate decarboxylase activity
D5R55_RS03130	COG1546	Belongs to the CinA family
D5R55_RS03135	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D5R55_RS03155	COG4290	ribonuclease
D5R55_RS03170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D5R55_RS03180	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D5R55_RS03185	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D5R55_RS03190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D5R55_RS03200	COG0583	DNA-binding transcription factor activity
D5R55_RS03205	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS03210	COG1063	alcohol dehydrogenase
D5R55_RS03220	COG1301	dicarboxylic acid transport
D5R55_RS03225	COG4266	Belongs to the allantoicase family
D5R55_RS03230	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
D5R55_RS03235	COG0735	belongs to the Fur family
D5R55_RS03240	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D5R55_RS03245	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D5R55_RS03265	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
D5R55_RS03270	COG1466	dna polymerase III delta subunit
D5R55_RS03285	COG1981	membrane
D5R55_RS03300	COG0800	Aldolase
D5R55_RS03315	COG3265	gluconokinase activity
D5R55_RS03325	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D5R55_RS03335	COG0583	DNA-binding transcription factor activity
D5R55_RS03340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D5R55_RS03350	COG0765	amino acid transport
D5R55_RS03355	COG0765	amino acid transport
D5R55_RS03360	COG1126	abc transporter atp-binding protein
D5R55_RS03365	COG3468	outer membrane autotransporter barrel domain protein
D5R55_RS03370	COG0121	glutamine amidotransferase
D5R55_RS03375	COG0418	dihydroorotase activity
D5R55_RS03400	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D5R55_RS03425	COG1490	D-aminoacyl-tRNA deacylase activity
D5R55_RS03430	COG0588	phosphoglycerate mutase activity
D5R55_RS03465	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
D5R55_RS03475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D5R55_RS03480	COG0006	proline dipeptidase activity
D5R55_RS03490	COG0625	glutathione transferase activity
D5R55_RS03495	COG0069	glutamate synthase activity
D5R55_RS03570	COG3008	intermembrane lipid transfer
D5R55_RS03570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D5R55_RS03575	COG2995	paraquat-inducible protein a
D5R55_RS03590	COG2353	YceI-like domain
D5R55_RS03605	COG0793	Belongs to the peptidase S41A family
D5R55_RS03610	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D5R55_RS03615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D5R55_RS03620	COG1862	Preprotein translocase
D5R55_RS03625	COG0343	queuine tRNA-ribosyltransferase activity
D5R55_RS03630	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D5R55_RS03635	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D5R55_RS03645	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
D5R55_RS03650	COG0783	Belongs to the Dps family
D5R55_RS03670	COG0247	lactate metabolic process
D5R55_RS03675	COG0277	FAD linked oxidase domain protein
D5R55_RS03680	COG0277	FAD linked oxidase domain protein
D5R55_RS03685	COG0277	FAD linked oxidase domain protein
D5R55_RS03690	COG2096	Adenosyltransferase
D5R55_RS03695	COG1017	nitric oxide dioxygenase activity
D5R55_RS03695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D5R55_RS03700	COG3744	PilT protein domain protein
D5R55_RS03710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D5R55_RS03715	COG0312	modulator of DNA gyrase
D5R55_RS03720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D5R55_RS03730	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
D5R55_RS03740	COG0497	DNA recombination
D5R55_RS03745	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D5R55_RS03770	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D5R55_RS03790	COG0512	Glutamine amidotransferase of anthranilate synthase
D5R55_RS03790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D5R55_RS03805	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D5R55_RS03815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D5R55_RS03820	COG0617	tRNA 3'-terminal CCA addition
D5R55_RS03830	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D5R55_RS03835	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D5R55_RS03860	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D5R55_RS03865	COG0586	Pfam SNARE associated Golgi protein
D5R55_RS03875	COG0529	Catalyzes the synthesis of activated sulfate
D5R55_RS03885	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D5R55_RS03895	COG4682	membrane
D5R55_RS03965	COG0824	Thioesterase
D5R55_RS03970	COG4221	oxidoreductase activity
D5R55_RS03985	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D5R55_RS04030	COG0450	alkyl hydroperoxide reductase
D5R55_RS04035	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS04070	COG2814	Major facilitator Superfamily
D5R55_RS04090	COG2814	Major facilitator Superfamily
D5R55_RS04095	COG0778	Nitroreductase
D5R55_RS04100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D5R55_RS04105	COG0583	DNA-binding transcription factor activity
D5R55_RS04110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D5R55_RS04115	COG4977	sequence-specific DNA binding
D5R55_RS04145	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D5R55_RS04175	COG2823	Periplasmic or secreted lipoprotein
D5R55_RS04205	COG0730	response to heat
D5R55_RS04215	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D5R55_RS04280	COG3842	ATPase activity
D5R55_RS04295	COG2837	iron assimilation
D5R55_RS04310	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D5R55_RS04325	COG1773	rubredoxin
D5R55_RS04335	COG1678	Uncharacterized ACR, COG1678
D5R55_RS04345	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D5R55_RS04395	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
D5R55_RS04395	COG0662	Cupin 2, conserved barrel domain protein
D5R55_RS04410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D5R55_RS04420	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
D5R55_RS04455	COG0546	phosphoglycolate phosphatase activity
D5R55_RS04455	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D5R55_RS04465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D5R55_RS04485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D5R55_RS04490	COG0438	transferase activity, transferring glycosyl groups
D5R55_RS04560	COG0829	nickel cation binding
D5R55_RS04580	COG1129	ABC transporter
D5R55_RS04590	COG0559	Belongs to the binding-protein-dependent transport system permease family
D5R55_RS04610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D5R55_RS04625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D5R55_RS04660	COG4948	Mandelate Racemase Muconate Lactonizing
D5R55_RS04680	COG0494	nUDIX hydrolase
D5R55_RS04690	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D5R55_RS04710	COG0762	integral membrane protein
D5R55_RS04745	COG0436	Aminotransferase
D5R55_RS04775	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D5R55_RS04775	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D5R55_RS04780	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D5R55_RS04795	COG2814	Major facilitator Superfamily
D5R55_RS04820	COG0363	glucosamine-6-phosphate deaminase activity
D5R55_RS04835	COG1175	transmembrane transport
D5R55_RS04840	COG0395	ABC-type sugar transport system, permease component
D5R55_RS04845	COG3842	ATPase activity
D5R55_RS04850	COG2860	membrane
D5R55_RS04855	COG1193	negative regulation of DNA recombination
D5R55_RS04860	COG0492	ferredoxin-NADP+ reductase activity
D5R55_RS04865	COG1674	ftsk spoiiie
D5R55_RS04870	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D5R55_RS04875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D5R55_RS04915	COG0850	regulation of cytokinetic process
D5R55_RS04920	COG2894	cell division
D5R55_RS04940	COG0859	PFAM glycosyl transferase family 9
D5R55_RS04950	COG0477	Major facilitator Superfamily
D5R55_RS04980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D5R55_RS04985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D5R55_RS04995	COG1561	YicC-like family, N-terminal region
D5R55_RS05010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D5R55_RS05035	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS05045	COG1278	Cold shock
D5R55_RS05065	COG4772	TonB-dependent receptor
D5R55_RS05100	COG0308	aminopeptidase N
D5R55_RS05110	COG2119	membrane
D5R55_RS05120	COG0402	S-adenosylhomocysteine deaminase activity
D5R55_RS05130	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D5R55_RS05145	COG0154	amidase activity
D5R55_RS05160	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D5R55_RS05195	COG3383	formate dehydrogenase (NAD+) activity
D5R55_RS05210	COG1910	domain protein
D5R55_RS05230	COG0546	phosphoglycolate phosphatase activity
D5R55_RS05235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D5R55_RS05265	COG0287	Prephenate dehydrogenase
D5R55_RS05285	COG0776	regulation of translation
D5R55_RS05295	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
D5R55_RS05305	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
D5R55_RS05325	COG2951	lytic endotransglycosylase activity
D5R55_RS05330	COG0123	including yeast histone deacetylase and acetoin utilization protein
D5R55_RS05335	COG2267	carboxylic ester hydrolase activity
D5R55_RS05345	COG2011	ABC-type metal ion transport system permease component
D5R55_RS05350	COG1464	Belongs to the NlpA lipoprotein family
D5R55_RS05380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS05445	COG0501	Belongs to the peptidase M48B family
D5R55_RS05450	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
D5R55_RS05455	COG0521	Mo-molybdopterin cofactor biosynthetic process
D5R55_RS05460	COG3028	Belongs to the UPF0307 family
D5R55_RS05465	COG0312	modulator of DNA gyrase
D5R55_RS05480	COG2204	response regulator
D5R55_RS05485	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D5R55_RS05505	COG0114	fumarate hydratase activity
D5R55_RS05515	COG2501	S4 domain
D5R55_RS05535	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D5R55_RS05545	COG3045	CreA protein
D5R55_RS05560	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D5R55_RS05590	COG1322	Protein conserved in bacteria
D5R55_RS05605	COG0303	'Molybdopterin
D5R55_RS05615	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D5R55_RS05620	COG1530	ribonuclease E activity
D5R55_RS05635	COG0546	phosphoglycolate phosphatase activity
D5R55_RS05645	COG0616	signal peptide processing
D5R55_RS05660	COG1399	metal-binding, possibly nucleic acid-binding protein
D5R55_RS05695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D5R55_RS05705	COG1595	DNA-templated transcription, initiation
D5R55_RS05720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D5R55_RS05735	COG0681	Belongs to the peptidase S26 family
D5R55_RS05740	COG0571	ribonuclease III activity
D5R55_RS05745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D5R55_RS05830	COG0024	Methionine aminopeptidase
D5R55_RS05835	COG1956	GAF domain-containing protein
D5R55_RS05850	COG2153	protein acetylation
D5R55_RS05865	COG1999	signal sequence binding
D5R55_RS05880	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
D5R55_RS05885	COG1132	(ABC) transporter
D5R55_RS05895	COG0438	transferase activity, transferring glycosyl groups
D5R55_RS05930	COG3511	phospholipase C
D5R55_RS05940	COG0596	Alpha beta hydrolase
D5R55_RS05945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS05955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D5R55_RS05960	COG3394	polysaccharide catabolic process
D5R55_RS06015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D5R55_RS06065	COG0450	alkyl hydroperoxide reductase
D5R55_RS06085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D5R55_RS06095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5R55_RS06150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D5R55_RS06160	COG0741	lytic transglycosylase activity
D5R55_RS06165	COG2197	response regulator
D5R55_RS06180	COG2197	response regulator
D5R55_RS06190	COG1459	type II secretion system
D5R55_RS06230	COG2165	general secretion pathway protein
D5R55_RS06245	COG0004	ammonium transporteR
D5R55_RS06260	COG1959	2 iron, 2 sulfur cluster binding
D5R55_RS06270	COG1522	sequence-specific DNA binding
D5R55_RS06275	COG3842	ATPase activity
D5R55_RS06280	COG1178	ABC-type Fe3 transport system permease component
D5R55_RS06285	COG1840	ABC-type Fe3 transport system, periplasmic component
D5R55_RS06305	COG1289	transmembrane transporter activity
D5R55_RS06310	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D5R55_RS06315	COG1074	ATP-dependent DNA helicase activity
D5R55_RS06320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D5R55_RS06330	COG2200	EAL domain
D5R55_RS06365	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
D5R55_RS06370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D5R55_RS06390	COG0697	spore germination
D5R55_RS06395	COG2814	Major facilitator Superfamily
D5R55_RS06400	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D5R55_RS06405	COG3842	ATPase activity
D5R55_RS06410	COG1177	transmembrane transport
D5R55_RS06420	COG1840	ABC-type Fe3 transport system, periplasmic component
D5R55_RS06425	COG1609	Transcriptional regulator
D5R55_RS06435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D5R55_RS06445	COG0022	dehydrogenase e1 component
D5R55_RS06460	COG0702	epimerase
D5R55_RS06465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D5R55_RS06480	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D5R55_RS06490	COG0583	DNA-binding transcription factor activity
D5R55_RS06495	COG0477	Major facilitator Superfamily
D5R55_RS06510	COG2814	Major facilitator Superfamily
D5R55_RS06515	COG0583	DNA-binding transcription factor activity
D5R55_RS06530	COG0583	DNA-binding transcription factor activity
D5R55_RS06535	COG1253	flavin adenine dinucleotide binding
D5R55_RS06555	COG1250	3-hydroxyacyl-CoA dehydrogenase
D5R55_RS06565	COG0583	DNA-binding transcription factor activity
D5R55_RS06585	COG3052	prosthetic group binding
D5R55_RS06605	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
D5R55_RS06640	COG0477	Major facilitator Superfamily
D5R55_RS06655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D5R55_RS06660	COG0328	RNA-DNA hybrid ribonuclease activity
D5R55_RS06665	COG2226	methyltransferase
D5R55_RS06670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D5R55_RS06675	COG1388	LysM domain
D5R55_RS06675	COG0741	lytic transglycosylase activity
D5R55_RS06680	COG2223	nitrite transmembrane transporter activity
D5R55_RS06690	COG0505	Belongs to the CarA family
D5R55_RS06700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D5R55_RS06705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D5R55_RS06715	COG1534	Rna-binding protein
D5R55_RS06725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D5R55_RS06730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D5R55_RS06745	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D5R55_RS06750	COG0573	inorganic phosphate transmembrane transporter activity
D5R55_RS06755	COG0581	inorganic phosphate transmembrane transporter activity
D5R55_RS06770	COG0745	RESPONSE REGULATOR receiver
D5R55_RS06820	COG0534	Mate efflux family protein
D5R55_RS06835	COG4942	peptidase
D5R55_RS06920	COG1309	transcriptional regulator
D5R55_RS06935	COG0367	asparagine synthase
D5R55_RS06950	COG3300	MHYT domain
D5R55_RS06950	COG5001	Diguanylate cyclase
D5R55_RS06970	COG4964	Belongs to the GSP D family
D5R55_RS07025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D5R55_RS07055	COG1215	transferase activity, transferring glycosyl groups
D5R55_RS07080	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS07090	COG1695	Transcriptional regulator
D5R55_RS07095	COG0446	pyridine nucleotide-disulphide oxidoreductase
D5R55_RS07095	COG1902	pentaerythritol trinitrate reductase activity
D5R55_RS07105	COG4774	siderophore transport
D5R55_RS07110	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
D5R55_RS07120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D5R55_RS07125	COG2205	protein histidine kinase activity
D5R55_RS07130	COG0745	RESPONSE REGULATOR receiver
D5R55_RS07155	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS07165	COG1595	DNA-templated transcription, initiation
D5R55_RS07170	COG3712	iron ion homeostasis
D5R55_RS07175	COG4774	siderophore transport
D5R55_RS07185	COG0583	DNA-binding transcription factor activity
D5R55_RS07195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D5R55_RS07205	COG2851	Citrate transporter
D5R55_RS07235	COG4589	Belongs to the CDS family
D5R55_RS07250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D5R55_RS07255	COG2267	carboxylic ester hydrolase activity
D5R55_RS07260	COG2453	phosphatase
D5R55_RS07260	COG0671	phosphoesterase, PA-phosphatase related
D5R55_RS07275	COG1215	transferase activity, transferring glycosyl groups
D5R55_RS07280	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D5R55_RS07285	COG0457	Tetratricopeptide repeat
D5R55_RS07305	COG1215	transferase activity, transferring glycosyl groups
D5R55_RS07310	COG2194	sulfuric ester hydrolase activity
D5R55_RS07320	COG1741	Belongs to the pirin family
D5R55_RS07330	COG0025	NhaP-type Na H and K H
D5R55_RS07345	COG0583	DNA-binding transcription factor activity
D5R55_RS07355	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D5R55_RS07385	COG1858	cytochrome C peroxidase
D5R55_RS07395	COG0494	nUDIX hydrolase
D5R55_RS07400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D5R55_RS07425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D5R55_RS07430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D5R55_RS07440	COG0477	Major facilitator Superfamily
D5R55_RS07455	COG2816	NAD+ diphosphatase activity
D5R55_RS07460	COG0824	Thioesterase
D5R55_RS07485	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS07490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D5R55_RS07495	COG0824	Thioesterase
D5R55_RS07500	COG0477	Major facilitator Superfamily
D5R55_RS07505	COG1335	isochorismatase
D5R55_RS07515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D5R55_RS07520	COG2301	Belongs to the HpcH HpaI aldolase family
D5R55_RS07525	COG2079	MmgE PrpD family protein
D5R55_RS07550	COG2301	Belongs to the HpcH HpaI aldolase family
D5R55_RS07560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D5R55_RS07570	COG2814	Major facilitator Superfamily
D5R55_RS07575	COG4702	Belongs to the UPF0303 family
D5R55_RS07580	COG3718	enzyme involved in inositol metabolism
D5R55_RS07590	COG3962	Belongs to the TPP enzyme family
D5R55_RS07595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D5R55_RS07610	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5R55_RS07615	COG1082	Xylose isomerase domain protein TIM barrel
D5R55_RS07630	COG0673	inositol 2-dehydrogenase activity
D5R55_RS07635	COG1737	Transcriptional regulator
D5R55_RS07650	COG0425	Belongs to the sulfur carrier protein TusA family
D5R55_RS07665	COG0745	RESPONSE REGULATOR receiver
D5R55_RS07675	COG5002	protein histidine kinase activity
D5R55_RS07685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D5R55_RS07690	COG0525	valine-tRNA ligase activity
D5R55_RS07700	COG0210	DNA helicase
D5R55_RS07705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D5R55_RS07710	COG2223	nitrite transmembrane transporter activity
D5R55_RS07715	COG0840	transmembrane signaling receptor activity
D5R55_RS07745	COG0583	DNA-binding transcription factor activity
D5R55_RS07755	COG0277	FAD linked oxidase domain protein
D5R55_RS07770	COG1295	ribonuclease BN
D5R55_RS07785	COG0477	Major facilitator Superfamily
D5R55_RS07800	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS07840	COG0583	DNA-binding transcription factor activity
D5R55_RS07845	COG2945	thiolester hydrolase activity
D5R55_RS07845	COG0596	Alpha beta hydrolase
D5R55_RS07850	COG0251	oxidation-reduction process
D5R55_RS07855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D5R55_RS07870	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D5R55_RS07875	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D5R55_RS07900	COG0776	regulation of translation
D5R55_RS07930	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
D5R55_RS07970	COG0583	DNA-binding transcription factor activity
D5R55_RS07975	COG0436	Aminotransferase
D5R55_RS07980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D5R55_RS07995	COG0195	Participates in both transcription termination and antitermination
D5R55_RS07995	COG2251	uridine kinase activity
D5R55_RS08015	COG2814	Major facilitator Superfamily
D5R55_RS08020	COG1566	PFAM secretion protein HlyD family protein
D5R55_RS08030	COG1846	Transcriptional regulator
D5R55_RS08040	COG1217	gtp-binding protein TYPA
D5R55_RS08050	COG0567	Dehydrogenase, E1 component
D5R55_RS08055	COG0508	dehydrogenase complex catalyzes the overall conversion of
D5R55_RS08060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D5R55_RS08065	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D5R55_RS08120	COG4964	Belongs to the GSP D family
D5R55_RS08185	COG0318	PFAM AMP-dependent synthetase and ligase
D5R55_RS08195	COG2814	Major facilitator Superfamily
D5R55_RS08220	COG1879	ABC-type sugar transport system periplasmic component
D5R55_RS08225	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5R55_RS08245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D5R55_RS08255	COG5002	protein histidine kinase activity
D5R55_RS08255	COG3850	Histidine kinase
D5R55_RS08265	COG3397	chitin binding
D5R55_RS08270	COG2165	general secretion pathway protein
D5R55_RS08280	COG1459	type II secretion system
D5R55_RS08285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D5R55_RS08320	COG2165	general secretion pathway protein
D5R55_RS08330	COG0745	RESPONSE REGULATOR receiver
D5R55_RS08340	COG3121	Chaperone
D5R55_RS08355	COG3038	cytochrome b561
D5R55_RS08365	COG0557	exoribonuclease II activity
D5R55_RS08370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D5R55_RS08375	COG3023	N-Acetylmuramoyl-L-alanine amidase
D5R55_RS08395	COG0765	amino acid transport
D5R55_RS08400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS08405	COG0167	dihydroorotate dehydrogenase activity
D5R55_RS08455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D5R55_RS08480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D5R55_RS08500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D5R55_RS08560	COG0667	Aldo Keto reductase
D5R55_RS08575	COG0583	DNA-binding transcription factor activity
D5R55_RS08580	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
D5R55_RS08585	COG0701	Predicted permease
D5R55_RS08630	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D5R55_RS08635	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D5R55_RS08640	COG4208	sulfate ABC transporter
D5R55_RS08645	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D5R55_RS08650	COG0583	DNA-binding transcription factor activity
D5R55_RS08655	COG1879	ABC-type sugar transport system periplasmic component
D5R55_RS08660	COG1129	ABC transporter
D5R55_RS08665	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5R55_RS08670	COG1609	Transcriptional regulator
D5R55_RS08675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D5R55_RS08680	COG0840	transmembrane signaling receptor activity
D5R55_RS08690	COG2766	serine protein kinase
D5R55_RS08695	COG2718	Belongs to the UPF0229 family
D5R55_RS08700	COG2719	SpoVR family
D5R55_RS08705	COG0477	Major facilitator Superfamily
D5R55_RS08710	COG0583	DNA-binding transcription factor activity
D5R55_RS08720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D5R55_RS08735	COG2957	Belongs to the agmatine deiminase family
D5R55_RS08740	COG3539	Fimbrial protein
D5R55_RS08745	COG3121	Chaperone
D5R55_RS08750	COG3188	usher protein
D5R55_RS08755	COG3121	Chaperone
D5R55_RS08775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS08785	COG0765	amino acid transport
D5R55_RS08825	COG0739	heme binding
D5R55_RS08830	COG1309	transcriptional regulator
D5R55_RS08840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D5R55_RS08855	COG3539	Fimbrial protein
D5R55_RS08860	COG3188	usher protein
D5R55_RS08865	COG3121	Chaperone
D5R55_RS08885	COG2175	clavaminate synthase activity
D5R55_RS08890	COG1120	ATPase activity
D5R55_RS08930	COG3486	L-lysine 6-monooxygenase (NADPH) activity
D5R55_RS08935	COG4774	siderophore transport
D5R55_RS08970	COG1473	amidohydrolase
D5R55_RS09020	COG1671	Belongs to the UPF0178 family
D5R55_RS09035	COG0494	nUDIX hydrolase
D5R55_RS09045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D5R55_RS09050	COG2851	Citrate transporter
D5R55_RS09065	COG3979	chitinase
D5R55_RS09100	COG2099	Precorrin-6x reductase
D5R55_RS09110	COG2807	transmembrane transport
D5R55_RS09115	COG1846	Transcriptional regulator
D5R55_RS09145	COG0625	glutathione transferase activity
D5R55_RS09155	COG3842	ATPase activity
D5R55_RS09160	COG1176	ABC-type spermidine putrescine transport system, permease component I
D5R55_RS09180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D5R55_RS09185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D5R55_RS09190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D5R55_RS09205	COG0583	DNA-binding transcription factor activity
D5R55_RS09210	COG2271	Major facilitator Superfamily
D5R55_RS09235	COG1846	Transcriptional regulator
D5R55_RS09255	COG1764	response to oxidative stress
D5R55_RS09260	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D5R55_RS09270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5R55_RS09280	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D5R55_RS09300	COG2192	nodulation
D5R55_RS09305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D5R55_RS09330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D5R55_RS09345	COG4771	TonB-dependent receptor
D5R55_RS09355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D5R55_RS09360	COG4172	Belongs to the ABC transporter superfamily
D5R55_RS09365	COG4239	(ABC) transporter, permease
D5R55_RS09370	COG4174	ABC transporter (Permease)
D5R55_RS09375	COG4166	transmembrane transport
D5R55_RS09380	COG4771	TonB-dependent receptor
D5R55_RS09385	COG1396	sequence-specific DNA binding
D5R55_RS09430	COG0598	Magnesium transport protein CorA
D5R55_RS09475	COG1609	Transcriptional regulator
D5R55_RS09480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D5R55_RS09490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D5R55_RS09505	COG2855	membrane
D5R55_RS09515	COG0038	chloride channel
D5R55_RS09525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5R55_RS09550	COG2204	response regulator
D5R55_RS09565	COG0730	response to heat
D5R55_RS09565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D5R55_RS09570	COG1177	transmembrane transport
D5R55_RS09575	COG1176	ABC-type spermidine putrescine transport system, permease component I
D5R55_RS09580	COG3842	ATPase activity
D5R55_RS09585	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D5R55_RS09595	COG3047	cAMP biosynthetic process
D5R55_RS09600	COG2070	2-Nitropropane dioxygenase
D5R55_RS09620	COG0726	polysaccharide deacetylase
D5R55_RS09635	COG1819	glycosyl
D5R55_RS09640	COG0137	argininosuccinate synthase activity
D5R55_RS09645	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D5R55_RS09660	COG0488	(ABC) transporter
D5R55_RS09670	COG2982	Protein involved in outer membrane biogenesis
D5R55_RS09675	COG1122	ATPase activity
D5R55_RS09680	COG0390	transport system, permease component
D5R55_RS09700	COG0583	DNA-binding transcription factor activity
D5R55_RS09705	COG0560	Phosphoserine phosphatase
D5R55_RS09710	COG0626	cystathionine gamma-synthase activity
D5R55_RS09810	COG3829	transcription factor binding
D5R55_RS09885	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS09890	COG0183	Belongs to the thiolase family
D5R55_RS09895	COG3243	poly(R)-hydroxyalkanoic acid synthase
D5R55_RS09905	COG0564	pseudouridine synthase activity
D5R55_RS09915	COG1199	ATP-dependent helicase activity
D5R55_RS09930	COG2183	response to ionizing radiation
D5R55_RS09945	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
D5R55_RS09965	COG0330	HflC and HflK could
D5R55_RS09970	COG0330	HflC and HflK could
D5R55_RS09975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D5R55_RS09985	COG1160	GTP binding
D5R55_RS09995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D5R55_RS10010	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D5R55_RS10030	COG0670	Belongs to the BI1 family
D5R55_RS10070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D5R55_RS10085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D5R55_RS10100	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D5R55_RS10110	COG0477	Major facilitator Superfamily
D5R55_RS10135	COG0534	Mate efflux family protein
D5R55_RS10140	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D5R55_RS10150	COG0022	dehydrogenase e1 component
D5R55_RS10155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D5R55_RS10160	COG3199	ATP-NAD kinase
D5R55_RS10165	COG3284	Transcriptional regulator
D5R55_RS10190	COG0542	response to heat
D5R55_RS10195	COG1959	2 iron, 2 sulfur cluster binding
D5R55_RS10205	COG2346	COG2346, Truncated hemoglobins
D5R55_RS10210	COG0314	molybdopterin synthase activity
D5R55_RS10215	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D5R55_RS10235	COG0436	Aminotransferase
D5R55_RS10245	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D5R55_RS10250	COG2076	Multidrug Resistance protein
D5R55_RS10255	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D5R55_RS10260	COG0463	Glycosyl transferase, family 2
D5R55_RS10270	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D5R55_RS10270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D5R55_RS10275	COG0726	polysaccharide deacetylase
D5R55_RS10280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D5R55_RS10290	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D5R55_RS10295	COG0791	NLP P60 protein
D5R55_RS10300	COG0306	phosphate transporter
D5R55_RS10310	COG0305	Participates in initiation and elongation during chromosome replication
D5R55_RS10325	COG2965	DNA replication, synthesis of RNA primer
D5R55_RS10345	COG0583	DNA-binding transcription factor activity
D5R55_RS10350	COG3960	tartronate-semialdehyde synthase activity
D5R55_RS10355	COG3622	Belongs to the hyi family
D5R55_RS10360	COG2084	Dehydrogenase
D5R55_RS10365	COG1652	LysM domain
D5R55_RS10370	COG0252	asparaginase activity
D5R55_RS10395	COG0438	transferase activity, transferring glycosyl groups
D5R55_RS10420	COG0084	hydrolase, TatD family'
D5R55_RS10435	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D5R55_RS10450	COG2153	protein acetylation
D5R55_RS10515	COG2203	Gaf domain
D5R55_RS10515	COG5001	Diguanylate cyclase
D5R55_RS10515	COG4251	negative regulation of phosphorylation
D5R55_RS10515	COG3706	GGDEF domain
D5R55_RS10535	COG0183	Belongs to the thiolase family
D5R55_RS10540	COG1335	isochorismatase
D5R55_RS10550	COG0318	PFAM AMP-dependent synthetase and ligase
D5R55_RS10565	COG2917	probably involved in intracellular septation
D5R55_RS10575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D5R55_RS10580	COG3153	acetyltransferase
D5R55_RS10585	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D5R55_RS10585	COG0047	phosphoribosylformylglycinamidine synthase activity
D5R55_RS10590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS10605	COG4181	ATPase activity
D5R55_RS10630	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D5R55_RS10655	COG1929	Belongs to the glycerate kinase type-1 family
D5R55_RS10665	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D5R55_RS10740	COG0582	viral genome integration into host DNA
D5R55_RS10790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D5R55_RS10805	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D5R55_RS10810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D5R55_RS10855	COG3360	Dodecin
D5R55_RS10875	COG2351	hydroxyisourate hydrolase activity
D5R55_RS10895	COG0251	oxidation-reduction process
D5R55_RS10910	COG4266	Belongs to the allantoicase family
D5R55_RS10915	COG3648	Uricase
D5R55_RS10915	COG3195	allantoin biosynthetic process
D5R55_RS10930	COG1953	Uracil, thiamine, allantoin
D5R55_RS10940	COG1619	proteins homologs of microcin C7 resistance protein MccF
D5R55_RS10945	COG0590	tRNA wobble adenosine to inosine editing
D5R55_RS10960	COG2188	Transcriptional regulator
D5R55_RS10965	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D5R55_RS11000	COG0456	acetyltransferase
D5R55_RS11010	COG2176	DNA-directed DNA polymerase activity
D5R55_RS11015	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D5R55_RS11020	COG2264	protein methyltransferase activity
D5R55_RS11040	COG0574	Belongs to the PEP-utilizing enzyme family
D5R55_RS11040	COG3848	Pyruvate phosphate dikinase
D5R55_RS11045	COG0574	Belongs to the PEP-utilizing enzyme family
D5R55_RS11045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D5R55_RS11065	COG0583	DNA-binding transcription factor activity
D5R55_RS11115	COG0697	spore germination
D5R55_RS11120	COG2914	Belongs to the UPF0125 (RnfH) family
D5R55_RS11135	COG0330	HflC and HflK could
D5R55_RS11155	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D5R55_RS11160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D5R55_RS11170	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D5R55_RS11180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D5R55_RS11185	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D5R55_RS11200	COG0750	zinc metalloprotease
D5R55_RS11215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D5R55_RS11220	COG0233	cytoplasmic translational termination
D5R55_RS11245	COG0024	Methionine aminopeptidase
D5R55_RS11255	COG1187	pseudouridine synthase activity
D5R55_RS11260	COG0242	peptide deformylase activity
D5R55_RS11295	COG1393	Belongs to the ArsC family
D5R55_RS11300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D5R55_RS11305	COG2890	protein-(glutamine-N5) methyltransferase activity
D5R55_RS11315	COG0386	Belongs to the glutathione peroxidase family
D5R55_RS11320	COG0488	(ABC) transporter
D5R55_RS11345	COG0351	phosphomethylpyrimidine kinase
D5R55_RS11355	COG1573	uracil-dna glycosylase
D5R55_RS11365	COG1214	PFAM Peptidase M22, glycoprotease
D5R55_RS11375	COG0513	Belongs to the DEAD box helicase family
D5R55_RS11385	COG2224	Isocitrate lyase
D5R55_RS11395	COG0583	DNA-binding transcription factor activity
D5R55_RS11405	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D5R55_RS11460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D5R55_RS11465	COG1752	Esterase of the alpha-beta hydrolase superfamily
D5R55_RS11470	COG0791	NLP P60 protein
D5R55_RS11475	COG4172	Belongs to the ABC transporter superfamily
D5R55_RS11480	COG4239	(ABC) transporter, permease
D5R55_RS11485	COG4174	ABC transporter (Permease)
D5R55_RS11510	COG0745	RESPONSE REGULATOR receiver
D5R55_RS11555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D5R55_RS11575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D5R55_RS11580	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS11610	COG2986	histidine ammonia-lyase
D5R55_RS11620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D5R55_RS11630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D5R55_RS11660	COG0527	aspartate kinase activity
D5R55_RS11665	COG0037	tRNA processing
D5R55_RS11695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D5R55_RS11705	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D5R55_RS11710	COG1045	serine acetyltransferase
D5R55_RS11720	COG0483	inositol monophosphate 1-phosphatase activity
D5R55_RS11725	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
D5R55_RS11755	COG2850	peptidyl-arginine hydroxylation
D5R55_RS11770	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D5R55_RS11775	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
D5R55_RS11780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D5R55_RS11790	COG0180	Tryptophanyl-tRNA synthetase
D5R55_RS11795	COG1994	Peptidase M50
D5R55_RS11800	COG0009	L-threonylcarbamoyladenylate synthase
D5R55_RS11805	COG0613	PHP domain protein
D5R55_RS11810	COG0596	Alpha beta hydrolase
D5R55_RS11815	COG2833	Protein of unknown function (DUF455)
D5R55_RS11825	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D5R55_RS11835	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D5R55_RS11860	COG2333	competence protein COMEC
D5R55_RS11860	COG0658	competence protein
D5R55_RS11865	COG0084	hydrolase, TatD family'
D5R55_RS11885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D5R55_RS11920	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D5R55_RS11925	COG0316	Belongs to the HesB IscA family
D5R55_RS11930	COG0822	iron-sulfur transferase activity
D5R55_RS11935	COG1104	cysteine desulfurase activity
D5R55_RS11945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D5R55_RS11965	COG1414	Transcriptional regulator
D5R55_RS11980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D5R55_RS11990	COG0508	dehydrogenase complex catalyzes the overall conversion of
D5R55_RS11995	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
D5R55_RS12010	COG4566	intracellular signal transduction
D5R55_RS12025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D5R55_RS12030	COG1794	racemase activity, acting on amino acids and derivatives
D5R55_RS12045	COG1505	serine-type exopeptidase activity
D5R55_RS12055	COG3852	Histidine kinase
D5R55_RS12060	COG0174	glutamine synthetase
D5R55_RS12070	COG1546	Belongs to the CinA family
D5R55_RS12070	COG1058	Belongs to the CinA family
D5R55_RS12090	COG1643	Atp-dependent helicase
D5R55_RS12095	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D5R55_RS12095	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D5R55_RS12105	COG0477	Major facilitator Superfamily
D5R55_RS12110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D5R55_RS12115	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS12120	COG0583	DNA-binding transcription factor activity
D5R55_RS12130	COG0529	Catalyzes the synthesis of activated sulfate
D5R55_RS12140	COG0174	glutamine synthetase
D5R55_RS12145	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D5R55_RS12165	COG1228	amidohydrolase
D5R55_RS12175	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D5R55_RS12185	COG2986	histidine ammonia-lyase
D5R55_RS12190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS12205	COG0583	DNA-binding transcription factor activity
D5R55_RS12215	COG0415	Belongs to the DNA photolyase family
D5R55_RS12265	COG2310	stress, protein
D5R55_RS12275	COG2304	oxidoreductase activity
D5R55_RS12395	COG0582	viral genome integration into host DNA
D5R55_RS12400	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D5R55_RS12440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D5R55_RS12470	COG1741	Belongs to the pirin family
D5R55_RS12495	COG0672	)-iron permease
D5R55_RS12500	COG4633	Protein conserved in bacteria
D5R55_RS12510	COG0556	nucleotide-excision repair
D5R55_RS12525	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS12530	COG0667	Aldo Keto reductase
D5R55_RS12535	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D5R55_RS12600	COG2866	Carboxypeptidase
D5R55_RS12615	COG0436	Aminotransferase
D5R55_RS12620	COG0625	glutathione transferase activity
D5R55_RS12625	COG1024	Enoyl-CoA hydratase
D5R55_RS12630	COG0625	glutathione transferase activity
D5R55_RS12645	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS12650	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS12670	COG1007	ATP synthesis coupled electron transport
D5R55_RS12695	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D5R55_RS12705	COG1034	ATP synthesis coupled electron transport
D5R55_RS12715	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
D5R55_RS12750	COG0149	triose-phosphate isomerase activity
D5R55_RS12755	COG0604	alcohol dehydrogenase
D5R55_RS12755	COG3321	synthase
D5R55_RS12755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D5R55_RS12755	COG4221	oxidoreductase activity
D5R55_RS12775	COG0683	leucine binding
D5R55_RS12785	COG0288	reversible hydration of carbon dioxide
D5R55_RS12790	COG0659	secondary active sulfate transmembrane transporter activity
D5R55_RS12805	COG1183	phosphatidylcholine synthase activity
D5R55_RS12810	COG0688	phosphatidylethanolamine metabolic process
D5R55_RS12825	COG0028	Belongs to the TPP enzyme family
D5R55_RS12855	COG0438	transferase activity, transferring glycosyl groups
D5R55_RS12875	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS12880	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D5R55_RS12890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D5R55_RS12920	COG0745	RESPONSE REGULATOR receiver
D5R55_RS12925	COG2205	protein histidine kinase activity
D5R55_RS12935	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
D5R55_RS12940	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
D5R55_RS12975	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS12990	COG0151	Belongs to the GarS family
D5R55_RS13000	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D5R55_RS13005	COG0799	negative regulation of ribosome biogenesis
D5R55_RS13020	COG1530	ribonuclease E activity
D5R55_RS13035	COG3171	Protein conserved in bacteria
D5R55_RS13075	COG1216	Glycosyl transferase, family 2
D5R55_RS13085	COG0859	PFAM glycosyl transferase family 9
D5R55_RS13100	COG1054	Belongs to the UPF0176 family
D5R55_RS13110	COG0513	Belongs to the DEAD box helicase family
D5R55_RS13120	COG3895	Periplasmic Protein
D5R55_RS13140	COG1674	ftsk spoiiie
D5R55_RS13145	COG2706	6-phosphogluconolactonase activity
D5R55_RS13155	COG3387	PFAM Glycoside hydrolase 15-related
D5R55_RS13165	COG1309	transcriptional regulator
D5R55_RS13170	COG2878	Part of a membrane complex involved in electron transport
D5R55_RS13175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D5R55_RS13200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D5R55_RS13210	COG3135	benzoate transporter
D5R55_RS13235	COG4106	trans-aconitate 2-methyltransferase activity
D5R55_RS13295	COG0697	spore germination
D5R55_RS13300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5R55_RS13310	COG0384	phenazine biosynthesis protein PhzF
D5R55_RS13320	COG5001	Diguanylate cyclase
D5R55_RS13325	COG2059	Chromate
D5R55_RS13335	COG0583	DNA-binding transcription factor activity
D5R55_RS13355	COG0488	(ABC) transporter
D5R55_RS13390	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D5R55_RS13415	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS13420	COG1309	transcriptional regulator
D5R55_RS13445	COG2814	Major facilitator Superfamily
D5R55_RS13475	COG1116	anion transmembrane transporter activity
D5R55_RS13480	COG1176	ABC-type spermidine putrescine transport system, permease component I
D5R55_RS13505	COG1741	Belongs to the pirin family
D5R55_RS13535	COG0583	DNA-binding transcription factor activity
D5R55_RS13560	COG1472	Belongs to the glycosyl hydrolase 3 family
D5R55_RS13570	COG2827	Endonuclease containing a URI domain
D5R55_RS13575	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D5R55_RS13590	COG2271	Major facilitator Superfamily
D5R55_RS13620	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
D5R55_RS13625	COG2226	methyltransferase
D5R55_RS13655	COG0165	Argininosuccinate lyase
D5R55_RS13660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D5R55_RS13685	COG0489	protein tyrosine kinase activity
D5R55_RS13690	COG3047	cAMP biosynthetic process
D5R55_RS13690	COG2885	chlorophyll binding
D5R55_RS13705	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D5R55_RS13705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D5R55_RS13725	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D5R55_RS13735	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D5R55_RS13745	COG2259	Doxx family
D5R55_RS13750	COG1492	cobalamin metabolic process
D5R55_RS13760	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
D5R55_RS13770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D5R55_RS13780	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
D5R55_RS13785	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
D5R55_RS13790	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
D5R55_RS13795	COG4139	cobalamin transport
D5R55_RS13825	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D5R55_RS13830	COG0583	DNA-binding transcription factor activity
D5R55_RS13855	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D5R55_RS13875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D5R55_RS13875	COG1648	precorrin-2 dehydrogenase activity
D5R55_RS13880	COG2895	sulfate adenylyltransferase (ATP) activity
D5R55_RS13890	COG0175	sulfate reduction
D5R55_RS13905	COG0583	DNA-binding transcription factor activity
D5R55_RS13935	COG0583	DNA-binding transcription factor activity
D5R55_RS13940	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS13945	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS13960	COG0583	DNA-binding transcription factor activity
D5R55_RS13965	COG4221	oxidoreductase activity
D5R55_RS13980	COG1187	pseudouridine synthase activity
D5R55_RS14000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D5R55_RS14005	COG0456	acetyltransferase
D5R55_RS14040	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D5R55_RS14045	COG1047	Peptidyl-prolyl cis-trans
D5R55_RS14065	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D5R55_RS14085	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
D5R55_RS14085	COG3264	Mechanosensitive ion channel
D5R55_RS14090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D5R55_RS14090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D5R55_RS14095	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D5R55_RS14100	COG0196	riboflavin kinase activity
D5R55_RS14115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D5R55_RS14120	COG0756	dUTP diphosphatase activity
D5R55_RS14130	COG1113	amino acid transport
D5R55_RS14135	COG0542	response to heat
D5R55_RS14150	COG1278	Cold shock
D5R55_RS14195	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
D5R55_RS14210	COG0656	L-ascorbic acid biosynthetic process
D5R55_RS14215	COG2188	Transcriptional regulator
D5R55_RS14220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D5R55_RS14240	COG2814	Major facilitator Superfamily
D5R55_RS14255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D5R55_RS14275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D5R55_RS14280	COG1570	exodeoxyribonuclease VII activity
D5R55_RS14290	COG1663	tetraacyldisaccharide 4'-kinase activity
D5R55_RS14300	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
D5R55_RS14315	COG0728	peptidoglycan biosynthetic process
D5R55_RS14350	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D5R55_RS14355	COG0318	PFAM AMP-dependent synthetase and ligase
D5R55_RS14360	COG4974	Belongs to the 'phage' integrase family
D5R55_RS14370	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D5R55_RS14375	COG0802	atpase or kinase
D5R55_RS14380	COG0860	N-Acetylmuramoyl-L-alanine amidase
D5R55_RS14395	COG1741	Belongs to the pirin family
D5R55_RS14405	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D5R55_RS14415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D5R55_RS14425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D5R55_RS14445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D5R55_RS14450	COG1522	sequence-specific DNA binding
D5R55_RS14465	COG3483	tryptophan 2,3-dioxygenase activity
D5R55_RS14470	COG0246	Mannitol dehydrogenase
D5R55_RS14475	COG1070	Carbohydrate kinase
D5R55_RS14480	COG2390	Transcriptional regulator
D5R55_RS14495	COG0583	DNA-binding transcription factor activity
D5R55_RS14500	COG3842	ATPase activity
D5R55_RS14515	COG4209	transmembrane transport
D5R55_RS14525	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
D5R55_RS14530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D5R55_RS14540	COG0735	belongs to the Fur family
D5R55_RS14550	COG1121	(ABC) transporter
D5R55_RS14555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D5R55_RS14560	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
D5R55_RS14570	COG1070	Carbohydrate kinase
D5R55_RS14575	COG2233	PERMEase
D5R55_RS14585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D5R55_RS14605	COG4977	sequence-specific DNA binding
D5R55_RS14625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D5R55_RS14640	COG2027	D-alanyl-D-alanine carboxypeptidase
D5R55_RS14655	COG0009	L-threonylcarbamoyladenylate synthase
D5R55_RS14660	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D5R55_RS14665	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D5R55_RS14670	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D5R55_RS14680	COG0469	pyruvate kinase activity
D5R55_RS14685	COG0126	phosphoglycerate kinase activity
D5R55_RS14720	COG0429	hydrolase of the alpha beta-hydrolase fold
D5R55_RS14730	COG4783	chaperone-mediated protein folding
D5R55_RS14755	COG4969	Belongs to the N-Me-Phe pilin family
D5R55_RS14760	COG0861	Integral membrane protein TerC family
D5R55_RS14765	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D5R55_RS14780	COG2137	regulation of response to DNA damage stimulus
D5R55_RS14785	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D5R55_RS14810	COG0583	DNA-binding transcription factor activity
D5R55_RS14815	COG4977	sequence-specific DNA binding
D5R55_RS14835	COG0583	DNA-binding transcription factor activity
D5R55_RS14850	COG3813	Protein conserved in bacteria
D5R55_RS14855	COG2186	Transcriptional regulator
D5R55_RS14860	COG4948	Mandelate Racemase Muconate Lactonizing
D5R55_RS14870	COG2863	cytochrome
D5R55_RS14880	COG0513	Belongs to the DEAD box helicase family
D5R55_RS14930	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D5R55_RS14965	COG0673	inositol 2-dehydrogenase activity
D5R55_RS14970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D5R55_RS14980	COG1396	sequence-specific DNA binding
D5R55_RS14985	COG2814	Major facilitator Superfamily
D5R55_RS14990	COG0583	DNA-binding transcription factor activity
D5R55_RS15000	COG1702	phosphate starvation-inducible protein PhoH
D5R55_RS15010	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D5R55_RS15020	COG0815	Transfers the fatty acyl group on membrane lipoproteins
D5R55_RS15030	COG0752	glycyl-tRNA synthetase alpha subunit
D5R55_RS15035	COG0751	glycine-tRNA ligase activity
D5R55_RS15040	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D5R55_RS15045	COG0204	Acyl-transferase
D5R55_RS15070	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D5R55_RS15095	COG5265	(ABC) transporter
D5R55_RS15115	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D5R55_RS15120	COG1024	Enoyl-CoA hydratase
D5R55_RS15125	COG0183	Belongs to the thiolase family
D5R55_RS15130	COG1250	3-hydroxyacyl-CoA dehydrogenase
D5R55_RS15130	COG1024	Enoyl-CoA hydratase
D5R55_RS15135	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS15150	COG0494	nUDIX hydrolase
D5R55_RS15170	COG0500	methyltransferase
D5R55_RS15215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D5R55_RS15225	COG0251	oxidation-reduction process
D5R55_RS15230	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
D5R55_RS15235	COG0837	glucose binding
D5R55_RS15235	COG1737	Transcriptional regulator
D5R55_RS15255	COG0477	Major facilitator Superfamily
D5R55_RS15275	COG0235	Class ii aldolase
D5R55_RS15280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D5R55_RS15290	COG0501	Belongs to the peptidase M48B family
D5R55_RS15305	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS15325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D5R55_RS15350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D5R55_RS15375	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS15380	COG0183	Belongs to the thiolase family
D5R55_RS15400	COG3663	DNA glycosylase
D5R55_RS15405	COG0629	single-stranded DNA binding
D5R55_RS15410	COG2814	Major facilitator Superfamily
D5R55_RS15440	COG1280	lysine exporter protein (LysE YggA)
D5R55_RS15460	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D5R55_RS15475	COG1137	ATPase activity
D5R55_RS15480	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D5R55_RS15485	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D5R55_RS15500	COG1660	Displays ATPase and GTPase activities
D5R55_RS15510	COG1194	a g-specific adenine glycosylase
D5R55_RS15530	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
D5R55_RS15545	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D5R55_RS15565	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D5R55_RS15575	COG0742	ribosomal rna small subunit methyltransferase
D5R55_RS15585	COG0625	glutathione transferase activity
D5R55_RS15590	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D5R55_RS15595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D5R55_RS15615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D5R55_RS15630	COG1294	oxidase, subunit
D5R55_RS15650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D5R55_RS15650	COG2190	(PTS) system
D5R55_RS15650	COG1263	PTS System
D5R55_RS15655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5R55_RS15655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D5R55_RS15660	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D5R55_RS15665	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D5R55_RS15670	COG2188	Transcriptional regulator
D5R55_RS15675	COG0587	DNA-directed DNA polymerase activity
D5R55_RS15705	COG0840	transmembrane signaling receptor activity
D5R55_RS15715	COG1999	signal sequence binding
D5R55_RS15725	COG1612	heme a metabolic process
D5R55_RS15760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D5R55_RS15775	COG2226	methyltransferase
D5R55_RS15780	COG1040	competence protein
D5R55_RS15790	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
D5R55_RS15800	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
D5R55_RS15810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D5R55_RS15820	COG0793	Belongs to the peptidase S41A family
D5R55_RS15825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D5R55_RS15830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D5R55_RS15835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5R55_RS15845	COG0189	ligase activity
D5R55_RS15855	COG0004	ammonium transporteR
D5R55_RS15865	COG2960	long-chain fatty acid transporting porin activity
D5R55_RS15870	COG0606	chelatase, subunit chli
D5R55_RS15895	COG4191	Histidine kinase
D5R55_RS15905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D5R55_RS15920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D5R55_RS15925	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS15930	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS15940	COG0583	DNA-binding transcription factor activity
D5R55_RS15945	COG0405	Gamma-glutamyltransferase
D5R55_RS15950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D5R55_RS15960	COG4521	taurine ABC transporter
D5R55_RS15980	COG0583	DNA-binding transcription factor activity
D5R55_RS15985	COG2921	Belongs to the UPF0250 family
D5R55_RS15995	COG1686	Belongs to the peptidase S11 family
D5R55_RS16025	COG1127	ABC transporter
D5R55_RS16030	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D5R55_RS16035	COG0737	Belongs to the 5'-nucleotidase family
D5R55_RS16050	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D5R55_RS16050	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D5R55_RS16055	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D5R55_RS16065	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D5R55_RS16090	COG1024	Enoyl-CoA hydratase
D5R55_RS16145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D5R55_RS16150	COG0300	oxidoreductase activity
D5R55_RS16155	COG0747	negative chemotaxis
D5R55_RS16160	COG0488	(ABC) transporter
D5R55_RS16190	COG0288	reversible hydration of carbon dioxide
D5R55_RS16195	COG0300	oxidoreductase activity
D5R55_RS16200	COG3012	SEC-C Motif Domain Protein
D5R55_RS16245	COG2199	diguanylate cyclase activity
D5R55_RS16245	COG2200	EAL domain
D5R55_RS16250	COG0025	NhaP-type Na H and K H
D5R55_RS16265	COG0110	maltose O-acetyltransferase activity
D5R55_RS16270	COG0625	glutathione transferase activity
D5R55_RS16290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D5R55_RS16305	COG0583	DNA-binding transcription factor activity
D5R55_RS16315	COG0625	glutathione transferase activity
D5R55_RS16320	COG0583	DNA-binding transcription factor activity
D5R55_RS16325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D5R55_RS16330	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D5R55_RS16335	COG2080	2 iron, 2 sulfur cluster binding
D5R55_RS16355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D5R55_RS16380	COG1522	sequence-specific DNA binding
D5R55_RS16385	COG0596	Alpha beta hydrolase
D5R55_RS16395	COG0583	DNA-binding transcription factor activity
D5R55_RS16430	COG1609	Transcriptional regulator
D5R55_RS16475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D5R55_RS16480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D5R55_RS16505	COG0672	)-iron permease
D5R55_RS16525	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS16540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D5R55_RS16545	COG0174	glutamine synthetase
D5R55_RS16560	COG3842	ATPase activity
D5R55_RS16565	COG1176	ABC-type spermidine putrescine transport system, permease component I
D5R55_RS16570	COG1177	transmembrane transport
D5R55_RS16580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS16585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS16605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D5R55_RS16620	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS16640	COG0583	DNA-binding transcription factor activity
D5R55_RS16645	COG2233	PERMEase
D5R55_RS16660	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D5R55_RS16675	COG1706	bacterial-type flagellum-dependent cell motility
D5R55_RS16700	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D5R55_RS16705	COG1558	bacterial-type flagellum-dependent cell motility
D5R55_RS16710	COG1815	bacterial-type flagellum-dependent cell motility
D5R55_RS16730	COG0006	proline dipeptidase activity
D5R55_RS16735	COG1396	sequence-specific DNA binding
D5R55_RS16740	COG0617	tRNA 3'-terminal CCA addition
D5R55_RS16755	COG0741	lytic transglycosylase activity
D5R55_RS16760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D5R55_RS16770	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D5R55_RS16775	COG1984	allophanate hydrolase subunit 2
D5R55_RS16790	COG4608	Belongs to the ABC transporter superfamily
D5R55_RS16795	COG0444	Belongs to the ABC transporter superfamily
D5R55_RS16800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D5R55_RS16805	COG0601	transmembrane transport
D5R55_RS16810	COG0747	negative chemotaxis
D5R55_RS16825	COG0579	oxidoreductase
D5R55_RS16830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D5R55_RS16845	COG3568	Endonuclease Exonuclease Phosphatase
D5R55_RS16860	COG2197	response regulator
D5R55_RS16865	COG0531	amino acid
D5R55_RS16880	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D5R55_RS16900	COG1677	Flagellar hook-basal body complex protein FliE
D5R55_RS16985	COG0667	Aldo Keto reductase
D5R55_RS17010	COG1560	Kdo2-lipid A biosynthetic process
D5R55_RS17015	COG3093	addiction module antidote protein HigA
D5R55_RS17025	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D5R55_RS17035	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D5R55_RS17045	COG0523	cobalamin synthesis protein
D5R55_RS17070	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
D5R55_RS17115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5R55_RS17120	COG2274	protein secretion by the type I secretion system
D5R55_RS17160	COG2813	Specifically methylates the guanine in position
D5R55_RS17160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D5R55_RS17165	COG2814	Major facilitator Superfamily
D5R55_RS17175	COG2207	Transcriptional regulator
D5R55_RS17180	COG1064	alcohol dehydrogenase
D5R55_RS17185	COG0708	Exodeoxyribonuclease III
D5R55_RS17190	COG2326	polyphosphate kinase activity
D5R55_RS17205	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D5R55_RS17210	COG1077	Cell shape determining protein MreB Mrl
D5R55_RS17225	COG0768	penicillin binding
D5R55_RS17230	COG0772	Belongs to the SEDS family
D5R55_RS17245	COG0720	synthase
D5R55_RS17250	COG0602	queuosine metabolic process
D5R55_RS17255	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D5R55_RS17265	COG2204	response regulator
D5R55_RS17270	COG5000	phosphorelay sensor kinase activity
D5R55_RS17295	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D5R55_RS17300	COG0242	peptide deformylase activity
D5R55_RS17305	COG0758	DNA mediated transformation
D5R55_RS17320	COG0583	DNA-binding transcription factor activity
D5R55_RS17325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D5R55_RS17360	COG1126	abc transporter atp-binding protein
D5R55_RS17365	COG0765	amino acid transport
D5R55_RS17370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS17375	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS17390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS17410	COG3511	phospholipase C
D5R55_RS17415	COG0583	DNA-binding transcription factor activity
D5R55_RS17420	COG1620	l-lactate permease
D5R55_RS17450	COG2169	Transcriptional regulator
D5R55_RS17450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D5R55_RS17475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D5R55_RS17485	COG3706	GGDEF domain
D5R55_RS17485	COG4251	negative regulation of phosphorylation
D5R55_RS17485	COG2203	Gaf domain
D5R55_RS17485	COG5001	Diguanylate cyclase
D5R55_RS17570	COG1280	lysine exporter protein (LysE YggA)
D5R55_RS17580	COG0583	DNA-binding transcription factor activity
D5R55_RS17585	COG3268	Saccharopine dehydrogenase
D5R55_RS17610	COG0840	transmembrane signaling receptor activity
D5R55_RS17640	COG0583	DNA-binding transcription factor activity
D5R55_RS17645	COG0583	DNA-binding transcription factor activity
D5R55_RS17655	COG0667	Aldo Keto reductase
D5R55_RS17660	COG1309	transcriptional regulator
D5R55_RS17665	COG1657	PFAM Prenyltransferase squalene oxidase
D5R55_RS17690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS17695	COG0583	DNA-binding transcription factor activity
D5R55_RS17720	COG2267	carboxylic ester hydrolase activity
D5R55_RS17750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D5R55_RS17755	COG0531	amino acid
D5R55_RS17810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS17835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS17840	COG1126	abc transporter atp-binding protein
D5R55_RS17845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS17850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS17860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS17870	COG0477	Major facilitator Superfamily
D5R55_RS17890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D5R55_RS17895	COG0601	transmembrane transport
D5R55_RS17900	COG0747	negative chemotaxis
D5R55_RS17910	COG4771	TonB-dependent receptor
D5R55_RS17920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS17930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS17935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS17940	COG3829	transcription factor binding
D5R55_RS17955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS17965	COG0765	amino acid transport
D5R55_RS17970	COG1126	abc transporter atp-binding protein
D5R55_RS17975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS17980	COG2079	MmgE PrpD family protein
D5R55_RS17985	COG2188	Transcriptional regulator
D5R55_RS17990	COG0471	metal ion transport
D5R55_RS18005	COG2814	Major facilitator Superfamily
D5R55_RS18025	COG2188	Transcriptional regulator
D5R55_RS18030	COG2986	histidine ammonia-lyase
D5R55_RS18060	COG2259	Doxx family
D5R55_RS18090	COG2271	Major facilitator Superfamily
D5R55_RS18095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D5R55_RS18105	COG1138	Cytochrome C-type biogenesis protein
D5R55_RS18115	COG0583	DNA-binding transcription factor activity
D5R55_RS18120	COG1741	Belongs to the pirin family
D5R55_RS18125	COG0655	NAD(P)H dehydrogenase (quinone) activity
D5R55_RS18135	COG1346	cytolysis
D5R55_RS18140	COG1380	Effector of murein hydrolase LrgA
D5R55_RS18150	COG1764	response to oxidative stress
D5R55_RS18155	COG1309	transcriptional regulator
D5R55_RS18160	COG1132	(ABC) transporter
D5R55_RS18200	COG0697	spore germination
D5R55_RS18215	COG0277	FAD linked oxidase domain protein
D5R55_RS18215	COG0247	lactate metabolic process
D5R55_RS18220	COG0583	DNA-binding transcription factor activity
D5R55_RS18225	COG0583	DNA-binding transcription factor activity
D5R55_RS18230	COG1280	lysine exporter protein (LysE YggA)
D5R55_RS18235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS18250	COG3829	transcription factor binding
D5R55_RS18255	COG2376	Dihydroxyacetone kinase
D5R55_RS18270	COG0477	Major facilitator Superfamily
D5R55_RS18275	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D5R55_RS18280	COG0583	DNA-binding transcription factor activity
D5R55_RS18305	COG1566	PFAM secretion protein HlyD family protein
D5R55_RS18340	COG0655	NAD(P)H dehydrogenase (quinone) activity
D5R55_RS18355	COG4977	sequence-specific DNA binding
D5R55_RS18360	COG1192	Involved in chromosome partitioning
D5R55_RS18365	COG1475	DNA binding
D5R55_RS18385	COG0583	DNA-binding transcription factor activity
D5R55_RS18400	COG0583	DNA-binding transcription factor activity
D5R55_RS18415	COG0583	DNA-binding transcription factor activity
D5R55_RS18420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5R55_RS18425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D5R55_RS18445	COG4977	sequence-specific DNA binding
D5R55_RS18470	COG5654	RES domain protein
D5R55_RS18475	COG4974	Belongs to the 'phage' integrase family
D5R55_RS18480	COG2233	PERMEase
D5R55_RS18490	COG0583	DNA-binding transcription factor activity
D5R55_RS18495	COG0405	Gamma-glutamyltransferase
D5R55_RS18505	COG2423	ornithine cyclodeaminase activity
D5R55_RS18510	COG0019	diaminopimelate decarboxylase activity
D5R55_RS18515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D5R55_RS18520	COG0534	Mate efflux family protein
D5R55_RS18525	COG2197	response regulator
D5R55_RS18545	COG1136	(ABC) transporter
D5R55_RS18550	COG4591	ABC-type transport system involved in lipoprotein release permease component
D5R55_RS18605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D5R55_RS18620	COG0318	PFAM AMP-dependent synthetase and ligase
D5R55_RS18650	COG0420	3'-5' exonuclease activity
D5R55_RS18740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D5R55_RS18750	COG0183	Belongs to the thiolase family
D5R55_RS18755	COG1309	transcriptional regulator
D5R55_RS18765	COG0493	'glutamate synthase
D5R55_RS18775	COG1953	Uracil, thiamine, allantoin
D5R55_RS18785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D5R55_RS18805	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D5R55_RS18815	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D5R55_RS18900	COG0745	RESPONSE REGULATOR receiver
D5R55_RS18905	COG5002	protein histidine kinase activity
D5R55_RS18920	COG0318	PFAM AMP-dependent synthetase and ligase
D5R55_RS18935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D5R55_RS18940	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
D5R55_RS18945	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS18955	COG0183	Belongs to the thiolase family
D5R55_RS18960	COG1250	3-hydroxyacyl-CoA dehydrogenase
D5R55_RS18990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D5R55_RS19005	COG1596	polysaccharide export
D5R55_RS19010	COG3206	protein involved in exopolysaccharide biosynthesis
D5R55_RS19010	COG0489	protein tyrosine kinase activity
D5R55_RS19050	COG1414	Transcriptional regulator
D5R55_RS19105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D5R55_RS19110	COG0745	RESPONSE REGULATOR receiver
D5R55_RS19115	COG2205	protein histidine kinase activity
D5R55_RS19120	COG1677	Flagellar hook-basal body complex protein FliE
D5R55_RS19125	COG1766	The M ring may be actively involved in energy transduction
D5R55_RS19130	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D5R55_RS19150	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D5R55_RS19170	COG1191	sigma factor activity
D5R55_RS19175	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D5R55_RS19180	COG1360	Flagellar Motor Protein
D5R55_RS19195	COG3951	Flagellar rod assembly protein muramidase FlgJ
D5R55_RS19195	COG1705	Flagellar rod assembly protein muramidase FlgJ
D5R55_RS19220	COG1749	Flagellar hook protein flgE
D5R55_RS19225	COG4786	Flagellar basal body rod
D5R55_RS19230	COG4786	Flagellar basal body rod
D5R55_RS19325	COG2197	response regulator
D5R55_RS19340	COG5295	Hep Hag repeat protein
D5R55_RS19355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS19355	COG2205	protein histidine kinase activity
D5R55_RS19380	COG2197	response regulator
D5R55_RS19390	COG0784	Response regulator, receiver
D5R55_RS19390	COG2205	protein histidine kinase activity
D5R55_RS19395	COG2197	response regulator
D5R55_RS19405	COG5295	Hep Hag repeat protein
D5R55_RS19435	COG1349	DNA-binding transcription factor activity
D5R55_RS19445	COG0738	Major facilitator superfamily
D5R55_RS19450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D5R55_RS19460	COG3609	addiction module antidote protein, CC2985 family
D5R55_RS19480	COG2814	Major facilitator Superfamily
D5R55_RS19485	COG0543	2 iron, 2 sulfur cluster binding
D5R55_RS19490	COG0167	dihydroorotate dehydrogenase activity
D5R55_RS19590	COG0840	transmembrane signaling receptor activity
D5R55_RS19605	COG0835	chemotaxis
D5R55_RS19625	COG1522	sequence-specific DNA binding
D5R55_RS19630	COG2515	1-aminocyclopropane-1-carboxylate deaminase
D5R55_RS19640	COG0583	DNA-binding transcription factor activity
D5R55_RS19660	COG0840	transmembrane signaling receptor activity
D5R55_RS19670	COG2205	protein histidine kinase activity
D5R55_RS19675	COG0583	DNA-binding transcription factor activity
D5R55_RS19680	COG1335	isochorismatase
D5R55_RS19685	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS19705	COG1538	Outer membrane efflux protein
D5R55_RS19710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5R55_RS19740	COG0765	amino acid transport
D5R55_RS19745	COG0765	amino acid transport
D5R55_RS19750	COG1126	abc transporter atp-binding protein
D5R55_RS19790	COG0583	DNA-binding transcription factor activity
D5R55_RS19810	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D5R55_RS19830	COG1234	tRNA 3'-trailer cleavage
D5R55_RS19870	COG1902	pentaerythritol trinitrate reductase activity
D5R55_RS19875	COG2814	Major facilitator Superfamily
D5R55_RS19880	COG0583	DNA-binding transcription factor activity
D5R55_RS19885	COG2010	Cytochrome c
D5R55_RS19885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D5R55_RS19890	COG2080	2 iron, 2 sulfur cluster binding
D5R55_RS19895	COG2010	Cytochrome c
D5R55_RS19895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D5R55_RS19955	COG0583	DNA-binding transcription factor activity
D5R55_RS19980	COG0494	nUDIX hydrolase
D5R55_RS19990	COG0300	oxidoreductase activity
D5R55_RS20000	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
D5R55_RS20010	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS20030	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS20045	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS20050	COG0583	DNA-binding transcription factor activity
D5R55_RS20060	COG0625	glutathione transferase activity
D5R55_RS20105	COG0589	response to stress
D5R55_RS20125	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D5R55_RS20145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5R55_RS20155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5R55_RS20160	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D5R55_RS20175	COG0314	molybdopterin synthase activity
D5R55_RS20180	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D5R55_RS20190	COG0303	'Molybdopterin
D5R55_RS20195	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D5R55_RS20200	COG1271	oxidase subunit
D5R55_RS20205	COG1294	oxidase, subunit
D5R55_RS20210	COG3781	membrane
D5R55_RS20245	COG2072	flavoprotein involved in K transport
D5R55_RS20275	COG3842	ATPase activity
D5R55_RS20280	COG4638	Rieske (2fe-2S)
D5R55_RS20285	COG0583	DNA-binding transcription factor activity
D5R55_RS20290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS20300	COG0765	amino acid transport
D5R55_RS20355	COG0243	molybdopterin cofactor binding
D5R55_RS20360	COG0542	response to heat
D5R55_RS20375	COG2837	iron assimilation
D5R55_RS20400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5R55_RS20410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D5R55_RS20425	COG2095	MarC family integral membrane protein
D5R55_RS20445	COG2205	protein histidine kinase activity
D5R55_RS20460	COG5265	(ABC) transporter
D5R55_RS20470	COG0300	oxidoreductase activity
D5R55_RS20475	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D5R55_RS20480	COG0859	PFAM glycosyl transferase family 9
D5R55_RS20485	COG2192	nodulation
D5R55_RS20500	COG0859	PFAM glycosyl transferase family 9
D5R55_RS20510	COG2204	response regulator
D5R55_RS20515	COG2204	response regulator
D5R55_RS20535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D5R55_RS20540	COG0438	transferase activity, transferring glycosyl groups
D5R55_RS20555	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS20570	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS20585	COG1914	H( )-stimulated, divalent metal cation uptake system
D5R55_RS20590	COG1573	uracil-dna glycosylase
D5R55_RS20635	COG3685	Protein conserved in bacteria
D5R55_RS20640	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D5R55_RS20665	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D5R55_RS20695	COG0693	protein deglycase activity
D5R55_RS20710	COG0688	phosphatidylethanolamine metabolic process
D5R55_RS20725	COG1640	4-alpha-glucanotransferase
D5R55_RS20730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D5R55_RS20745	COG0366	Alpha amylase catalytic
D5R55_RS20750	COG0366	Alpha amylase catalytic
D5R55_RS20775	COG1285	pathogenesis
D5R55_RS20785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D5R55_RS20820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D5R55_RS20825	COG0546	phosphoglycolate phosphatase activity
D5R55_RS20840	COG0583	DNA-binding transcription factor activity
D5R55_RS20850	COG1522	sequence-specific DNA binding
D5R55_RS20855	COG4774	siderophore transport
D5R55_RS20875	COG4178	(ABC) transporter
D5R55_RS20880	COG3118	belongs to the thioredoxin family
D5R55_RS20885	COG0312	modulator of DNA gyrase
D5R55_RS20890	COG0312	modulator of DNA gyrase
D5R55_RS20900	COG1595	DNA-templated transcription, initiation
D5R55_RS20920	COG1846	Transcriptional regulator
D5R55_RS20945	COG0124	histidyl-tRNA synthetase
D5R55_RS21005	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS21010	COG0251	oxidation-reduction process
D5R55_RS21015	COG4221	oxidoreductase activity
D5R55_RS21040	COG3657	addiction module killer protein
D5R55_RS21045	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D5R55_RS21065	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D5R55_RS21070	COG0028	Belongs to the TPP enzyme family
D5R55_RS21100	COG0494	nUDIX hydrolase
D5R55_RS21105	COG1566	PFAM secretion protein HlyD family protein
D5R55_RS21110	COG2814	Major facilitator Superfamily
D5R55_RS21120	COG0745	RESPONSE REGULATOR receiver
D5R55_RS21150	COG2824	Alkylphosphonate utilization operon protein PhnA
D5R55_RS21195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS21220	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5R55_RS21250	COG3550	peptidyl-serine autophosphorylation
D5R55_RS21255	COG1396	sequence-specific DNA binding
D5R55_RS21260	COG1285	pathogenesis
D5R55_RS21265	COG0517	IMP dehydrogenase activity
D5R55_RS21290	COG2175	clavaminate synthase activity
D5R55_RS21305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D5R55_RS21315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS21325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D5R55_RS21330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS21340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D5R55_RS21370	COG3275	phosphorelay sensor kinase activity
D5R55_RS21400	COG1024	Enoyl-CoA hydratase
D5R55_RS21410	COG0318	PFAM AMP-dependent synthetase and ligase
D5R55_RS21415	COG4221	oxidoreductase activity
D5R55_RS21425	COG3047	cAMP biosynthetic process
D5R55_RS21435	COG3321	synthase
D5R55_RS21435	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS21435	COG0604	alcohol dehydrogenase
D5R55_RS21440	COG1063	alcohol dehydrogenase
D5R55_RS21445	COG0604	alcohol dehydrogenase
D5R55_RS21470	COG4221	oxidoreductase activity
D5R55_RS21480	COG1309	transcriptional regulator
D5R55_RS21495	COG3459	Glycosyltransferase 36 associated
D5R55_RS21660	COG1764	response to oxidative stress
D5R55_RS21675	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D5R55_RS21685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D5R55_RS21690	COG1881	PFAM PEBP family protein
D5R55_RS21705	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D5R55_RS21720	COG1733	regulation of RNA biosynthetic process
D5R55_RS21725	COG0702	epimerase
D5R55_RS21770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS21775	COG0251	oxidation-reduction process
D5R55_RS21780	COG0683	leucine binding
D5R55_RS21805	COG0477	Major facilitator Superfamily
D5R55_RS21835	COG0071	Belongs to the small heat shock protein (HSP20) family
D5R55_RS21840	COG3958	Transketolase
D5R55_RS21845	COG3959	Transketolase, thiamine diphosphate binding domain
D5R55_RS21850	COG2271	Major facilitator Superfamily
D5R55_RS21855	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS21860	COG0583	DNA-binding transcription factor activity
D5R55_RS21865	COG0583	DNA-binding transcription factor activity
D5R55_RS21870	COG1301	dicarboxylic acid transport
D5R55_RS21885	COG3706	GGDEF domain
D5R55_RS21895	COG0702	epimerase
D5R55_RS21915	COG1473	amidohydrolase
D5R55_RS21925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS21945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS21955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D5R55_RS21960	COG0601	transmembrane transport
D5R55_RS21990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D5R55_RS22000	COG1522	sequence-specific DNA binding
D5R55_RS22005	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS22055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5R55_RS22105	COG1733	regulation of RNA biosynthetic process
D5R55_RS22125	COG0436	Aminotransferase
D5R55_RS22140	COG1609	Transcriptional regulator
D5R55_RS22145	COG0129	dihydroxy-acid dehydratase activity
D5R55_RS22155	COG0583	DNA-binding transcription factor activity
D5R55_RS22160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS22175	COG0840	transmembrane signaling receptor activity
D5R55_RS22180	COG0840	transmembrane signaling receptor activity
D5R55_RS22195	COG2721	sulfolactate sulfo-lyase activity
D5R55_RS22200	COG0246	Mannitol dehydrogenase
D5R55_RS22205	COG1063	alcohol dehydrogenase
D5R55_RS22225	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5R55_RS22235	COG2186	Transcriptional regulator
D5R55_RS22245	COG0471	metal ion transport
D5R55_RS22245	COG0490	domain, Protein
D5R55_RS22270	COG4191	Histidine kinase
D5R55_RS22285	COG4214	carbohydrate transport
D5R55_RS22295	COG4213	ABC transporter substrate-binding protein
D5R55_RS22300	COG1070	Carbohydrate kinase
D5R55_RS22315	COG1609	Transcriptional regulator
D5R55_RS22315	COG2207	Transcriptional regulator
D5R55_RS22320	COG2017	converts alpha-aldose to the beta-anomer
D5R55_RS22330	COG0589	response to stress
D5R55_RS22345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D5R55_RS22385	COG0583	DNA-binding transcription factor activity
D5R55_RS22390	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS22395	COG2207	Transcriptional regulator
D5R55_RS22415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D5R55_RS22420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D5R55_RS22440	COG0477	Major facilitator Superfamily
D5R55_RS22445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D5R55_RS22450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D5R55_RS22495	COG4774	siderophore transport
D5R55_RS22520	COG2814	Major facilitator Superfamily
D5R55_RS22530	COG0395	ABC-type sugar transport system, permease component
D5R55_RS22535	COG1175	transmembrane transport
D5R55_RS22545	COG3842	ATPase activity
D5R55_RS22550	COG1609	Transcriptional regulator
D5R55_RS22580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D5R55_RS22630	COG4964	Belongs to the GSP D family
D5R55_RS22680	COG0463	Glycosyl transferase, family 2
D5R55_RS22725	COG0596	Alpha beta hydrolase
D5R55_RS22730	COG1309	transcriptional regulator
D5R55_RS22750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D5R55_RS22755	COG0346	lactoylglutathione lyase activity
D5R55_RS22765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D5R55_RS22770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D5R55_RS22775	COG2814	Major facilitator Superfamily
D5R55_RS22780	COG0583	DNA-binding transcription factor activity
D5R55_RS22785	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS22800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D5R55_RS22825	COG4221	oxidoreductase activity
D5R55_RS22835	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D5R55_RS22840	COG0174	glutamine synthetase
D5R55_RS22845	COG0583	DNA-binding transcription factor activity
D5R55_RS22850	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS22870	COG1116	anion transmembrane transporter activity
D5R55_RS22875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D5R55_RS22885	COG4770	biotin carboxylase activity
D5R55_RS22920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D5R55_RS22930	COG2995	paraquat-inducible protein a
D5R55_RS22935	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D5R55_RS22935	COG3008	intermembrane lipid transfer
D5R55_RS22950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D5R55_RS22965	COG0318	PFAM AMP-dependent synthetase and ligase
D5R55_RS23005	COG0596	Alpha beta hydrolase
D5R55_RS23015	COG0583	DNA-binding transcription factor activity
D5R55_RS23045	COG0583	DNA-binding transcription factor activity
D5R55_RS23055	COG3850	Histidine kinase
D5R55_RS23055	COG5002	protein histidine kinase activity
D5R55_RS23095	COG1301	dicarboxylic acid transport
D5R55_RS23110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS23115	COG0583	DNA-binding transcription factor activity
D5R55_RS23185	COG1301	dicarboxylic acid transport
D5R55_RS23220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D5R55_RS23230	COG2264	protein methyltransferase activity
D5R55_RS23240	COG1301	dicarboxylic acid transport
D5R55_RS23250	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D5R55_RS23260	COG0745	RESPONSE REGULATOR receiver
D5R55_RS23275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D5R55_RS23285	COG0604	alcohol dehydrogenase
D5R55_RS23285	COG3321	synthase
D5R55_RS23290	COG0604	alcohol dehydrogenase
D5R55_RS23295	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS23305	COG2030	dehydratase
D5R55_RS23315	COG1301	dicarboxylic acid transport
D5R55_RS23325	COG3530	Putative quorum-sensing-regulated virulence factor
D5R55_RS23355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS23355	COG2205	protein histidine kinase activity
D5R55_RS23365	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5R55_RS23370	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5R55_RS23375	COG1129	ABC transporter
D5R55_RS23380	COG1879	ABC-type sugar transport system periplasmic component
D5R55_RS23395	COG0583	DNA-binding transcription factor activity
D5R55_RS23410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D5R55_RS23430	COG0517	IMP dehydrogenase activity
D5R55_RS23430	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D5R55_RS23435	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
D5R55_RS23440	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D5R55_RS23445	COG2877	3-deoxy-8-phosphooctulonate synthase activity
D5R55_RS23460	COG1045	serine acetyltransferase
D5R55_RS23475	COG3206	protein involved in exopolysaccharide biosynthesis
D5R55_RS23475	COG0489	protein tyrosine kinase activity
D5R55_RS23480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D5R55_RS23505	COG2267	carboxylic ester hydrolase activity
D5R55_RS23510	COG0583	DNA-binding transcription factor activity
D5R55_RS23540	COG1136	(ABC) transporter
D5R55_RS23545	COG4591	ABC-type transport system involved in lipoprotein release permease component
D5R55_RS23595	COG0318	PFAM AMP-dependent synthetase and ligase
D5R55_RS23605	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS23615	COG2226	methyltransferase
D5R55_RS23665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D5R55_RS23670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D5R55_RS23740	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS23755	COG1902	pentaerythritol trinitrate reductase activity
D5R55_RS23775	COG1621	beta-fructofuranosidase activity
D5R55_RS23785	COG0583	DNA-binding transcription factor activity
D5R55_RS23800	COG0753	catalase activity
D5R55_RS23815	COG1764	response to oxidative stress
D5R55_RS23835	COG2205	protein histidine kinase activity
D5R55_RS23840	COG4566	intracellular signal transduction
D5R55_RS23845	COG4566	intracellular signal transduction
D5R55_RS23880	COG1309	transcriptional regulator
D5R55_RS23890	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D5R55_RS23895	COG2814	Major facilitator Superfamily
D5R55_RS23905	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D5R55_RS23915	COG1309	transcriptional regulator
D5R55_RS23925	COG1131	(ABC) transporter
D5R55_RS23930	COG0842	Transport permease protein
D5R55_RS23940	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS23945	COG1562	ergosterol biosynthetic process
D5R55_RS23970	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS23985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D5R55_RS23995	COG1116	anion transmembrane transporter activity
D5R55_RS24015	COG0642	Histidine kinase
D5R55_RS24045	COG3842	ATPase activity
D5R55_RS24055	COG0604	alcohol dehydrogenase
D5R55_RS24065	COG2207	Transcriptional regulator
D5R55_RS24075	COG3971	2-oxopent-4-enoate hydratase activity
D5R55_RS24085	COG3384	dioxygenase
D5R55_RS24090	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS24105	COG1846	Transcriptional regulator
D5R55_RS24125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D5R55_RS24125	COG4651	solute:proton antiporter activity
D5R55_RS24160	COG0686	Belongs to the AlaDH PNT family
D5R55_RS24165	COG1796	DNA polymerase
D5R55_RS24165	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D5R55_RS24180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D5R55_RS24195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D5R55_RS24205	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D5R55_RS24225	COG0297	glycogen (starch) synthase activity
D5R55_RS24260	COG1596	polysaccharide export
D5R55_RS24290	COG1472	Belongs to the glycosyl hydrolase 3 family
D5R55_RS24300	COG0583	DNA-binding transcription factor activity
D5R55_RS24305	COG1739	Uncharacterized protein family UPF0029
D5R55_RS24335	COG1201	RNA secondary structure unwinding
D5R55_RS24340	COG0531	amino acid
D5R55_RS24355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5R55_RS24380	COG0583	DNA-binding transcription factor activity
D5R55_RS24395	COG3485	protocatechuate 3,4-dioxygenase
D5R55_RS24400	COG3485	protocatechuate 3,4-dioxygenase
D5R55_RS24430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D5R55_RS24440	COG0747	negative chemotaxis
D5R55_RS24445	COG4172	Belongs to the ABC transporter superfamily
D5R55_RS24460	COG2271	Major facilitator Superfamily
D5R55_RS24515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS24520	COG3938	Belongs to the proline racemase family
D5R55_RS24525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D5R55_RS24530	COG0531	amino acid
D5R55_RS24540	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D5R55_RS24550	COG0129	dihydroxy-acid dehydratase activity
D5R55_RS24575	COG0789	Transcriptional regulator
D5R55_RS24585	COG2814	Major facilitator Superfamily
D5R55_RS24625	COG0028	Belongs to the TPP enzyme family
D5R55_RS24625	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
D5R55_RS24630	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D5R55_RS24690	COG1305	Transglutaminase-like
D5R55_RS24715	COG2308	Evidence 4 Homologs of previously reported genes of
D5R55_RS24725	COG0583	DNA-binding transcription factor activity
D5R55_RS24750	COG0726	polysaccharide deacetylase
D5R55_RS24750	COG1649	PFAM Uncharacterised BCR, COG1649
D5R55_RS24755	COG1215	transferase activity, transferring glycosyl groups
D5R55_RS24805	COG3634	alkyl hydroperoxide reductase activity
D5R55_RS24820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D5R55_RS24830	COG1126	abc transporter atp-binding protein
D5R55_RS24835	COG0765	amino acid transport
D5R55_RS24840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS24870	COG1024	Enoyl-CoA hydratase
D5R55_RS24910	COG0840	transmembrane signaling receptor activity
D5R55_RS24925	COG0400	carboxylic ester hydrolase activity
D5R55_RS24940	COG0583	DNA-binding transcription factor activity
D5R55_RS24980	COG5001	Diguanylate cyclase
D5R55_RS24980	COG4251	negative regulation of phosphorylation
D5R55_RS24980	COG2203	Gaf domain
D5R55_RS24980	COG3706	GGDEF domain
D5R55_RS24990	COG0583	DNA-binding transcription factor activity
D5R55_RS25015	COG0477	Major facilitator Superfamily
D5R55_RS25075	COG0583	DNA-binding transcription factor activity
D5R55_RS25080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D5R55_RS25105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D5R55_RS25110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D5R55_RS25125	COG2175	clavaminate synthase activity
D5R55_RS25130	COG0747	negative chemotaxis
D5R55_RS25140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D5R55_RS25150	COG0583	DNA-binding transcription factor activity
D5R55_RS25155	COG0531	amino acid
D5R55_RS25160	COG1982	Orn Lys Arg decarboxylase major
D5R55_RS25170	COG1982	Orn Lys Arg decarboxylase major
D5R55_RS25180	COG1454	alcohol dehydrogenase
D5R55_RS25200	COG2233	PERMEase
D5R55_RS25205	COG0494	nUDIX hydrolase
D5R55_RS25220	COG3179	chitinase
D5R55_RS25240	COG1404	Belongs to the peptidase S8 family
D5R55_RS25250	COG2197	response regulator
D5R55_RS25270	COG2197	response regulator
D5R55_RS25275	COG1129	ABC transporter
D5R55_RS25300	COG2271	Major facilitator Superfamily
D5R55_RS25305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D5R55_RS25325	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS25350	COG0583	DNA-binding transcription factor activity
D5R55_RS25365	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
D5R55_RS25425	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D5R55_RS25440	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D5R55_RS25445	COG4790	Type iii secretion
D5R55_RS25450	COG4794	Type iii secretion
D5R55_RS25620	COG3276	selenocysteine insertion sequence binding
D5R55_RS25635	COG2864	formate dehydrogenase
D5R55_RS25640	COG0437	4 iron, 4 sulfur cluster binding
D5R55_RS25645	COG0243	molybdopterin cofactor binding
D5R55_RS25645	COG3383	formate dehydrogenase (NAD+) activity
D5R55_RS25650	COG0243	molybdopterin cofactor binding
D5R55_RS25650	COG3383	formate dehydrogenase (NAD+) activity
D5R55_RS25655	COG1295	ribonuclease BN
D5R55_RS25660	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS25690	COG2755	lipolytic protein G-D-S-L family
D5R55_RS25690	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D5R55_RS25695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D5R55_RS25720	COG2755	lipolytic protein G-D-S-L family
D5R55_RS25720	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D5R55_RS25725	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
D5R55_RS25755	COG0285	dihydrofolate synthase activity
D5R55_RS25760	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D5R55_RS25765	COG0159	tryptophan synthase activity
D5R55_RS25775	COG0133	tryptophan synthase activity
D5R55_RS25780	COG0135	phosphoribosylanthranilate isomerase activity
D5R55_RS25850	COG0833	amino acid
D5R55_RS25855	COG1522	sequence-specific DNA binding
D5R55_RS25880	COG0372	Belongs to the citrate synthase family
D5R55_RS25885	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
D5R55_RS25890	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D5R55_RS25895	COG1053	succinate dehydrogenase
D5R55_RS25905	COG2009	succinate dehydrogenase
D5R55_RS25910	COG2188	Transcriptional regulator
D5R55_RS25935	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D5R55_RS25950	COG1515	deoxyribonuclease V activity
D5R55_RS26015	COG2814	Major facilitator Superfamily
D5R55_RS26020	COG1177	transmembrane transport
D5R55_RS26025	COG1176	ABC-type spermidine putrescine transport system, permease component I
D5R55_RS26035	COG3842	ATPase activity
D5R55_RS26050	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D5R55_RS26055	COG4771	TonB-dependent receptor
D5R55_RS26070	COG3038	cytochrome b561
D5R55_RS26095	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D5R55_RS26120	COG0668	transmembrane transport
D5R55_RS26145	COG0753	catalase activity
D5R55_RS26160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D5R55_RS26170	COG0745	RESPONSE REGULATOR receiver
D5R55_RS26200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D5R55_RS26230	COG2081	HI0933 family
D5R55_RS26250	COG0142	geranyltranstransferase activity
D5R55_RS26270	COG0412	Dienelactone hydrolase
D5R55_RS26280	COG1252	NADH dehydrogenase
D5R55_RS26285	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D5R55_RS26285	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D5R55_RS26290	COG1611	Belongs to the LOG family
D5R55_RS26300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D5R55_RS26310	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D5R55_RS26320	COG1846	Transcriptional regulator
D5R55_RS26325	COG1764	response to oxidative stress
D5R55_RS26345	COG0725	ABC transporter, periplasmic molybdate-binding protein
D5R55_RS26350	COG4149	molybdate abc transporter
D5R55_RS26355	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D5R55_RS26370	COG1942	4-Oxalocrotonate Tautomerase
D5R55_RS26375	COG0583	DNA-binding transcription factor activity
D5R55_RS26390	COG1253	flavin adenine dinucleotide binding
D5R55_RS26395	COG0352	thiamine-phosphate diphosphorylase activity
D5R55_RS26400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D5R55_RS26420	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D5R55_RS26425	COG5654	RES domain protein
D5R55_RS26430	COG5642	Protein of unknown function (DUF2384)
D5R55_RS26435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS26455	COG2204	response regulator
D5R55_RS26470	COG3708	Transcriptional regulator
D5R55_RS26470	COG2207	Transcriptional regulator
D5R55_RS26485	COG2814	Major facilitator Superfamily
D5R55_RS26495	COG0438	transferase activity, transferring glycosyl groups
D5R55_RS26500	COG0438	transferase activity, transferring glycosyl groups
D5R55_RS26520	COG0489	protein tyrosine kinase activity
D5R55_RS26520	COG3206	protein involved in exopolysaccharide biosynthesis
D5R55_RS26540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D5R55_RS26560	COG0247	lactate metabolic process
D5R55_RS26565	COG1592	Rubrerythrin
D5R55_RS26570	COG4941	Belongs to the sigma-70 factor family
D5R55_RS26580	COG3795	YCII-related domain
D5R55_RS26585	COG3795	YCII-related domain
D5R55_RS26605	COG0628	permease
D5R55_RS26615	COG2130	NADP-dependent
D5R55_RS26630	COG1914	H( )-stimulated, divalent metal cation uptake system
D5R55_RS26650	COG2837	iron assimilation
D5R55_RS26660	COG5265	(ABC) transporter
D5R55_RS26670	COG0307	riboflavin synthase, alpha
D5R55_RS26680	COG0038	chloride channel
D5R55_RS26710	COG0840	transmembrane signaling receptor activity
D5R55_RS26720	COG0745	RESPONSE REGULATOR receiver
D5R55_RS26725	COG0025	NhaP-type Na H and K H
D5R55_RS26730	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS26745	COG3657	addiction module killer protein
D5R55_RS26750	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D5R55_RS26765	COG2733	membrane
D5R55_RS26775	COG2146	nitrite reductase [NAD(P)H] activity
D5R55_RS26780	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
D5R55_RS26785	COG4638	Rieske (2fe-2S)
D5R55_RS26820	COG2249	NAD(P)H dehydrogenase (quinone) activity
D5R55_RS26825	COG0583	DNA-binding transcription factor activity
D5R55_RS26835	COG0446	pyridine nucleotide-disulphide oxidoreductase
D5R55_RS26835	COG1902	pentaerythritol trinitrate reductase activity
D5R55_RS26860	COG0583	DNA-binding transcription factor activity
D5R55_RS26870	COG1566	PFAM secretion protein HlyD family protein
D5R55_RS26885	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D5R55_RS26935	COG0840	transmembrane signaling receptor activity
D5R55_RS26945	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D5R55_RS26960	COG3243	poly(R)-hydroxyalkanoic acid synthase
D5R55_RS26975	COG2113	Glycine betaine
D5R55_RS26980	COG0583	DNA-binding transcription factor activity
D5R55_RS26990	COG0006	proline dipeptidase activity
D5R55_RS27050	COG0583	DNA-binding transcription factor activity
D5R55_RS27060	COG0833	amino acid
D5R55_RS27065	COG3706	GGDEF domain
D5R55_RS27070	COG1289	transmembrane transporter activity
D5R55_RS27105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D5R55_RS27110	COG2831	hemolysin activation secretion protein
D5R55_RS27115	COG3210	domain, Protein
D5R55_RS27115	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
D5R55_RS27115	COG3064	Membrane
D5R55_RS27135	COG0583	DNA-binding transcription factor activity
D5R55_RS27140	COG0583	DNA-binding transcription factor activity
D5R55_RS27160	COG2226	methyltransferase
D5R55_RS27165	COG4650	regulator
D5R55_RS27180	COG1690	Belongs to the RtcB family
D5R55_RS27195	COG4122	O-methyltransferase activity
D5R55_RS27285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D5R55_RS27285	COG1017	nitric oxide dioxygenase activity
D5R55_RS27290	COG0625	glutathione transferase activity
D5R55_RS27375	COG0431	NADPH-dependent FMN reductase
D5R55_RS27385	COG2885	chlorophyll binding
D5R55_RS27400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D5R55_RS27475	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS27490	COG3842	ATPase activity
D5R55_RS27495	COG1176	ABC-type spermidine putrescine transport system, permease component I
D5R55_RS27500	COG1177	transmembrane transport
D5R55_RS27515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS27530	COG1250	3-hydroxyacyl-CoA dehydrogenase
D5R55_RS27535	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D5R55_RS27545	COG0583	DNA-binding transcription factor activity
D5R55_RS27550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS27555	COG2271	Major facilitator Superfamily
D5R55_RS27585	COG4191	Histidine kinase
D5R55_RS27590	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS27605	COG0154	amidase activity
D5R55_RS27615	COG4566	intracellular signal transduction
D5R55_RS27635	COG1522	sequence-specific DNA binding
D5R55_RS27675	COG0586	Pfam SNARE associated Golgi protein
D5R55_RS27730	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D5R55_RS27755	COG2211	Major facilitator Superfamily
D5R55_RS27760	COG1472	Belongs to the glycosyl hydrolase 3 family
D5R55_RS27795	COG0583	DNA-binding transcription factor activity
D5R55_RS27800	COG2072	flavoprotein involved in K transport
D5R55_RS27820	COG0443	Heat shock 70 kDa protein
D5R55_RS27840	COG0583	DNA-binding transcription factor activity
D5R55_RS27855	COG1011	Hydrolase
D5R55_RS27860	COG0625	glutathione transferase activity
D5R55_RS27885	COG0667	Aldo Keto reductase
D5R55_RS27910	COG1024	Enoyl-CoA hydratase
D5R55_RS27915	COG5001	Diguanylate cyclase
D5R55_RS27925	COG2814	Major facilitator Superfamily
D5R55_RS27960	COG1464	Belongs to the NlpA lipoprotein family
D5R55_RS27965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D5R55_RS27990	COG1064	alcohol dehydrogenase
D5R55_RS27995	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D5R55_RS28020	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D5R55_RS28025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D5R55_RS28030	COG1396	sequence-specific DNA binding
D5R55_RS28035	COG1045	serine acetyltransferase
D5R55_RS28080	COG0154	amidase activity
D5R55_RS28110	COG0596	Alpha beta hydrolase
D5R55_RS28115	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS28120	COG0583	DNA-binding transcription factor activity
D5R55_RS28125	COG0259	pyridoxamine-phosphate oxidase activity
D5R55_RS28135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5R55_RS28165	COG0583	DNA-binding transcription factor activity
D5R55_RS28195	COG0280	phosphate acetyltransferase
D5R55_RS28195	COG0281	malic enzyme
D5R55_RS28270	COG3237	CsbD-like
D5R55_RS28280	COG2823	Periplasmic or secreted lipoprotein
D5R55_RS28295	COG0583	DNA-binding transcription factor activity
D5R55_RS28310	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS28340	COG4774	siderophore transport
D5R55_RS28345	COG1902	pentaerythritol trinitrate reductase activity
D5R55_RS28360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D5R55_RS28365	COG1609	Transcriptional regulator
D5R55_RS28370	COG2271	Major facilitator Superfamily
D5R55_RS28395	COG1522	sequence-specific DNA binding
D5R55_RS28420	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
D5R55_RS28425	COG0631	protein serine/threonine phosphatase activity
D5R55_RS28430	COG4245	von Willebrand factor, type A
D5R55_RS28445	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D5R55_RS28465	COG1733	regulation of RNA biosynthetic process
D5R55_RS28485	COG0642	Histidine kinase
D5R55_RS28490	COG0745	RESPONSE REGULATOR receiver
D5R55_RS28645	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D5R55_RS28650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5R55_RS28670	COG1733	regulation of RNA biosynthetic process
D5R55_RS28680	COG2271	Major facilitator Superfamily
D5R55_RS28695	COG4106	trans-aconitate 2-methyltransferase activity
D5R55_RS28700	COG0583	DNA-binding transcription factor activity
D5R55_RS28710	COG0590	tRNA wobble adenosine to inosine editing
D5R55_RS28715	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
D5R55_RS28725	COG0583	DNA-binding transcription factor activity
D5R55_RS28740	COG0583	DNA-binding transcription factor activity
D5R55_RS28750	COG0583	DNA-binding transcription factor activity
D5R55_RS28755	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
D5R55_RS28760	COG0667	Aldo Keto reductase
D5R55_RS28770	COG0477	Major facilitator Superfamily
D5R55_RS28795	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS28800	COG2223	nitrite transmembrane transporter activity
D5R55_RS28805	COG4948	Mandelate Racemase Muconate Lactonizing
D5R55_RS28810	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
D5R55_RS28845	COG4175	Glycine betaine
D5R55_RS28850	COG4176	ABC-type proline glycine betaine transport system permease component
D5R55_RS28860	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS28880	COG0028	Belongs to the TPP enzyme family
D5R55_RS28885	COG1522	sequence-specific DNA binding
D5R55_RS28895	COG1522	sequence-specific DNA binding
D5R55_RS28915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D5R55_RS28925	COG0297	glycogen (starch) synthase activity
D5R55_RS28945	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D5R55_RS28970	COG3121	Chaperone
D5R55_RS28980	COG2205	protein histidine kinase activity
D5R55_RS28980	COG0784	Response regulator, receiver
D5R55_RS28985	COG2197	response regulator
D5R55_RS29025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS29025	COG2205	protein histidine kinase activity
D5R55_RS29030	COG0432	Pfam Uncharacterised protein family UPF0047
D5R55_RS29040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D5R55_RS29065	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
D5R55_RS29085	COG1522	sequence-specific DNA binding
D5R55_RS29130	COG0583	DNA-binding transcription factor activity
D5R55_RS29135	COG0667	Aldo Keto reductase
D5R55_RS29140	COG5265	(ABC) transporter
D5R55_RS29170	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS29180	COG1473	amidohydrolase
D5R55_RS29185	COG0583	DNA-binding transcription factor activity
D5R55_RS29190	COG0431	NADPH-dependent FMN reductase
D5R55_RS29195	COG0798	PFAM Bile acid sodium symporter
D5R55_RS29205	COG0640	Transcriptional regulator
D5R55_RS29210	COG2351	hydroxyisourate hydrolase activity
D5R55_RS29230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D5R55_RS29255	COG0739	heme binding
D5R55_RS29260	COG0668	transmembrane transport
D5R55_RS29280	COG0513	Belongs to the DEAD box helicase family
D5R55_RS29300	COG3135	benzoate transporter
D5R55_RS29385	COG2885	chlorophyll binding
D5R55_RS29425	COG0583	DNA-binding transcription factor activity
D5R55_RS29430	COG1252	NADH dehydrogenase
D5R55_RS29455	COG1716	ATPase activity
D5R55_RS29455	COG5001	Diguanylate cyclase
D5R55_RS29475	COG0583	DNA-binding transcription factor activity
D5R55_RS29480	COG0417	DNA replication proofreading
D5R55_RS29500	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS29505	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS29530	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS29540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS29545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D5R55_RS29550	COG0318	PFAM AMP-dependent synthetase and ligase
D5R55_RS29580	COG2409	Drug exporters of the RND superfamily
D5R55_RS29605	COG1309	transcriptional regulator
D5R55_RS29625	COG0745	RESPONSE REGULATOR receiver
D5R55_RS29630	COG2205	protein histidine kinase activity
D5R55_RS29645	COG0395	ABC-type sugar transport system, permease component
D5R55_RS29650	COG1063	alcohol dehydrogenase
D5R55_RS29665	COG1070	Carbohydrate kinase
D5R55_RS29685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D5R55_RS29695	COG1301	dicarboxylic acid transport
D5R55_RS29720	COG0662	Cupin 2, conserved barrel domain protein
D5R55_RS29760	COG1278	Cold shock
D5R55_RS29855	COG2814	Major facilitator Superfamily
D5R55_RS29860	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D5R55_RS29865	COG0596	Alpha beta hydrolase
D5R55_RS29875	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D5R55_RS29900	COG0302	gtp cyclohydrolase
D5R55_RS29905	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS29910	COG1045	serine acetyltransferase
D5R55_RS29930	COG0589	response to stress
D5R55_RS29935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D5R55_RS29985	COG1063	alcohol dehydrogenase
D5R55_RS29990	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS30030	COG1358	cellular component organization or biogenesis
D5R55_RS30045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D5R55_RS30050	COG1695	Transcriptional regulator
D5R55_RS30065	COG0671	phosphoesterase, PA-phosphatase related
D5R55_RS30080	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS30105	COG0583	DNA-binding transcription factor activity
D5R55_RS30110	COG0473	3-isopropylmalate dehydrogenase activity
D5R55_RS30125	COG1309	transcriptional regulator
D5R55_RS30135	COG1063	alcohol dehydrogenase
D5R55_RS30145	COG1396	sequence-specific DNA binding
D5R55_RS30175	COG1192	Involved in chromosome partitioning
D5R55_RS30190	COG1595	DNA-templated transcription, initiation
D5R55_RS30210	COG3437	response regulator, receiver
D5R55_RS30240	COG1562	ergosterol biosynthetic process
D5R55_RS30245	COG1233	COG1233 Phytoene dehydrogenase and related
D5R55_RS30250	COG1657	PFAM Prenyltransferase squalene oxidase
D5R55_RS30275	COG2197	response regulator
D5R55_RS30285	COG4251	negative regulation of phosphorylation
D5R55_RS30285	COG3706	GGDEF domain
D5R55_RS30285	COG2203	Gaf domain
D5R55_RS30285	COG5001	Diguanylate cyclase
D5R55_RS30290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D5R55_RS30295	COG3193	protein, possibly involved in utilization of glycolate and propanediol
D5R55_RS30300	COG0513	Belongs to the DEAD box helicase family
D5R55_RS30320	COG0395	ABC-type sugar transport system, permease component
D5R55_RS30325	COG1175	transmembrane transport
D5R55_RS30345	COG1609	Transcriptional regulator
D5R55_RS30350	COG2186	Transcriptional regulator
D5R55_RS30415	COG1024	Enoyl-CoA hydratase
D5R55_RS30420	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS30425	COG1022	Amp-dependent synthetase and ligase
D5R55_RS30425	COG3320	Male sterility
D5R55_RS30430	COG2814	Major facilitator Superfamily
D5R55_RS30435	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS30445	COG1522	sequence-specific DNA binding
D5R55_RS30455	COG1473	amidohydrolase
D5R55_RS30500	COG0583	DNA-binding transcription factor activity
D5R55_RS30530	COG2188	Transcriptional regulator
D5R55_RS30535	COG1396	sequence-specific DNA binding
D5R55_RS30540	COG0235	Class ii aldolase
D5R55_RS30545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D5R55_RS30550	COG2258	MOSC domain
D5R55_RS30555	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS30570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D5R55_RS30580	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D5R55_RS30585	COG1966	Carbon starvation protein
D5R55_RS30590	COG2879	small protein
D5R55_RS30595	COG2814	Major facilitator Superfamily
D5R55_RS30600	COG0640	Transcriptional regulator
D5R55_RS30605	COG1272	protein, Hemolysin III
D5R55_RS30645	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D5R55_RS30670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D5R55_RS30695	COG3104	oligopeptide transport
D5R55_RS30715	COG0601	transmembrane transport
D5R55_RS30720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D5R55_RS30730	COG4608	Belongs to the ABC transporter superfamily
D5R55_RS30760	COG1247	-acetyltransferase
D5R55_RS30775	COG2610	gluconate transmembrane transporter activity
D5R55_RS30780	COG3604	Transcriptional regulator
D5R55_RS30795	COG2916	Histone family protein nucleoid-structuring protein H-NS
D5R55_RS30800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D5R55_RS30800	COG1042	CoA-binding domain protein
D5R55_RS30800	COG0045	succinate-CoA ligase (ADP-forming) activity
D5R55_RS30860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D5R55_RS30870	COG2026	Addiction module toxin, RelE StbE family
D5R55_RS30880	COG0840	transmembrane signaling receptor activity
D5R55_RS30890	COG1285	pathogenesis
D5R55_RS30940	COG0583	DNA-binding transcription factor activity
D5R55_RS30950	COG3842	ATPase activity
D5R55_RS30955	COG1840	ABC-type Fe3 transport system, periplasmic component
D5R55_RS30990	COG1294	oxidase, subunit
D5R55_RS30995	COG1271	oxidase subunit
D5R55_RS31000	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
D5R55_RS31035	COG2814	Major facilitator Superfamily
D5R55_RS31055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D5R55_RS31060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D5R55_RS31105	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS31135	COG1090	epimerase
D5R55_RS31140	COG0625	glutathione transferase activity
D5R55_RS31170	COG3257	ureidoglycine aminohydrolase activity
D5R55_RS31200	COG2860	membrane
D5R55_RS31210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D5R55_RS31215	COG4558	Periplasmic binding protein
D5R55_RS31220	COG3720	iron ion transport
D5R55_RS31225	COG4771	TonB-dependent receptor
D5R55_RS31245	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS31265	COG0583	DNA-binding transcription factor activity
D5R55_RS31275	COG2814	Major facilitator Superfamily
D5R55_RS31290	COG2252	PERMEase
D5R55_RS31315	COG1902	pentaerythritol trinitrate reductase activity
D5R55_RS31325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS31335	COG2814	Major facilitator Superfamily
D5R55_RS31340	COG0583	DNA-binding transcription factor activity
D5R55_RS31345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D5R55_RS31350	COG1309	transcriptional regulator
D5R55_RS31355	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS31360	COG1414	Transcriptional regulator
D5R55_RS31365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D5R55_RS31370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D5R55_RS31375	COG3386	PFAM SMP-30 Gluconolaconase
D5R55_RS31395	COG2814	Major facilitator Superfamily
D5R55_RS31415	COG0577	efflux transmembrane transporter activity
D5R55_RS31415	COG1136	(ABC) transporter
D5R55_RS31420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5R55_RS31425	COG1538	Outer membrane efflux protein
D5R55_RS31455	COG4977	sequence-specific DNA binding
D5R55_RS31465	COG4221	oxidoreductase activity
D5R55_RS31475	COG4771	TonB-dependent receptor
D5R55_RS31480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5R55_RS31485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D5R55_RS31500	COG2207	Transcriptional regulator
D5R55_RS31520	COG1473	amidohydrolase
D5R55_RS31555	COG1414	Transcriptional regulator
D5R55_RS31560	COG0183	Belongs to the thiolase family
D5R55_RS31570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D5R55_RS31575	COG0840	transmembrane signaling receptor activity
D5R55_RS31580	COG0840	transmembrane signaling receptor activity
D5R55_RS31590	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D5R55_RS31620	COG0583	DNA-binding transcription factor activity
D5R55_RS31635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5R55_RS31660	COG1309	transcriptional regulator
D5R55_RS31700	COG2204	response regulator
D5R55_RS31705	COG4191	Histidine kinase
D5R55_RS31710	COG3493	citrate carrier protein
D5R55_RS31730	COG2011	ABC-type metal ion transport system permease component
D5R55_RS31750	COG1522	sequence-specific DNA binding
D5R55_RS31775	COG2271	Major facilitator Superfamily
D5R55_RS31795	COG1845	cytochrome c oxidase, subunit III
D5R55_RS31805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D5R55_RS31810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D5R55_RS31835	COG2721	sulfolactate sulfo-lyase activity
D5R55_RS31850	COG2259	Doxx family
D5R55_RS31880	COG3185	4-Hydroxyphenylpyruvate dioxygenase
D5R55_RS31880	COG1082	Xylose isomerase domain protein TIM barrel
D5R55_RS31885	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D5R55_RS31890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D5R55_RS31895	COG2271	Major facilitator Superfamily
D5R55_RS31935	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS31975	COG0477	Major facilitator Superfamily
D5R55_RS31985	COG0306	phosphate transporter
D5R55_RS32005	COG0583	DNA-binding transcription factor activity
D5R55_RS32015	COG0477	Major facilitator Superfamily
D5R55_RS32035	COG1280	lysine exporter protein (LysE YggA)
D5R55_RS32065	COG1349	DNA-binding transcription factor activity
D5R55_RS32080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS32085	COG0833	amino acid
D5R55_RS32090	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS32095	COG1511	domain protein
D5R55_RS32095	COG3264	Mechanosensitive ion channel
D5R55_RS32120	COG2271	Major facilitator Superfamily
D5R55_RS32130	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS32145	COG2252	PERMEase
D5R55_RS32150	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D5R55_RS32170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5R55_RS32200	COG0596	Alpha beta hydrolase
D5R55_RS32215	COG1280	lysine exporter protein (LysE YggA)
D5R55_RS32220	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS32245	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS32280	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS32285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D5R55_RS32290	COG1250	3-hydroxyacyl-CoA dehydrogenase
D5R55_RS32290	COG1024	Enoyl-CoA hydratase
D5R55_RS32310	COG3511	phospholipase C
D5R55_RS32330	COG3300	MHYT domain
D5R55_RS32330	COG5001	Diguanylate cyclase
D5R55_RS32405	COG4175	Glycine betaine
D5R55_RS32425	COG2860	membrane
D5R55_RS32445	COG0583	DNA-binding transcription factor activity
D5R55_RS32485	COG0642	Histidine kinase
D5R55_RS32510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D5R55_RS32515	COG3622	Belongs to the hyi family
D5R55_RS32520	COG2271	Major facilitator Superfamily
D5R55_RS32525	COG0235	Class ii aldolase
D5R55_RS32530	COG3395	kinase activity
D5R55_RS32535	COG2084	Dehydrogenase
D5R55_RS32540	COG2186	Transcriptional regulator
D5R55_RS32550	COG1760	l-serine dehydratase
D5R55_RS32565	COG0446	pyridine nucleotide-disulphide oxidoreductase
D5R55_RS32565	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D5R55_RS32585	COG3550	peptidyl-serine autophosphorylation
D5R55_RS32605	COG1174	glycine betaine transport
D5R55_RS32610	COG1125	glycine betaine transport
D5R55_RS32615	COG1174	glycine betaine transport
D5R55_RS32620	COG1732	Glycine betaine
D5R55_RS32625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D5R55_RS32635	COG2936	dipeptidyl-peptidase activity
D5R55_RS32655	COG2373	Large extracellular alpha-helical protein
D5R55_RS32660	COG4953	penicillin-binding protein 1C
D5R55_RS32665	COG0840	transmembrane signaling receptor activity
D5R55_RS32700	COG3284	Transcriptional regulator
D5R55_RS32715	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D5R55_RS32720	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
D5R55_RS32730	COG0535	radical SAM domain protein
D5R55_RS32755	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
D5R55_RS32770	COG3795	YCII-related domain
D5R55_RS32790	COG2814	Major facilitator Superfamily
D5R55_RS32795	COG0842	Transport permease protein
D5R55_RS32800	COG1131	(ABC) transporter
D5R55_RS32860	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS32865	COG1309	transcriptional regulator
D5R55_RS32885	COG2814	Major facilitator Superfamily
D5R55_RS32920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5R55_RS32940	COG3121	Chaperone
D5R55_RS32955	COG2197	response regulator
D5R55_RS32960	COG0784	Response regulator, receiver
D5R55_RS32960	COG2205	protein histidine kinase activity
D5R55_RS32985	COG0446	pyridine nucleotide-disulphide oxidoreductase
D5R55_RS32985	COG1902	pentaerythritol trinitrate reductase activity
D5R55_RS32990	COG0247	lactate metabolic process
D5R55_RS32990	COG2181	nitrate reductase activity
D5R55_RS32995	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D5R55_RS33005	COG4638	Rieske (2fe-2S)
D5R55_RS33015	COG2113	Glycine betaine
D5R55_RS33040	COG3119	arylsulfatase activity
D5R55_RS33055	COG5295	Hep Hag repeat protein
D5R55_RS33090	COG2207	Transcriptional regulator
D5R55_RS33145	COG3246	L-lysine catabolic process to acetate
D5R55_RS33150	COG1250	3-hydroxyacyl-CoA dehydrogenase
D5R55_RS33160	COG0657	acetylesterase activity
D5R55_RS33170	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D5R55_RS33170	COG2755	lipolytic protein G-D-S-L family
D5R55_RS33180	COG4221	oxidoreductase activity
D5R55_RS33190	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS33195	COG0179	Fumarylacetoacetate (FAA) hydrolase
D5R55_RS33200	COG4948	Mandelate Racemase Muconate Lactonizing
D5R55_RS33215	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5R55_RS33225	COG3618	amidohydrolase
D5R55_RS33230	COG2186	Transcriptional regulator
D5R55_RS33240	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
D5R55_RS33255	COG5001	Diguanylate cyclase
D5R55_RS33255	COG3300	MHYT domain
D5R55_RS33280	COG3209	COG3209 Rhs family protein
D5R55_RS33375	COG2197	response regulator
D5R55_RS33385	COG2205	protein histidine kinase activity
D5R55_RS33385	COG0784	Response regulator, receiver
D5R55_RS33405	COG0300	oxidoreductase activity
D5R55_RS33410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D5R55_RS33415	COG0583	DNA-binding transcription factor activity
D5R55_RS33425	COG2814	Major facilitator Superfamily
D5R55_RS33445	COG1280	lysine exporter protein (LysE YggA)
D5R55_RS33480	COG3284	Transcriptional regulator
D5R55_RS33495	COG2252	PERMEase
D5R55_RS33555	COG0330	HflC and HflK could
D5R55_RS33570	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS33575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D5R55_RS33590	COG1024	Enoyl-CoA hydratase
D5R55_RS33595	COG1024	Enoyl-CoA hydratase
D5R55_RS33600	COG0583	DNA-binding transcription factor activity
D5R55_RS33605	COG0477	Major facilitator Superfamily
D5R55_RS33610	COG1538	Outer membrane efflux protein
D5R55_RS33620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5R55_RS33680	COG0583	DNA-binding transcription factor activity
D5R55_RS33700	COG1309	transcriptional regulator
D5R55_RS33705	COG0596	Alpha beta hydrolase
D5R55_RS33710	COG2807	transmembrane transport
D5R55_RS33715	COG2066	Belongs to the glutaminase family
D5R55_RS33720	COG0745	RESPONSE REGULATOR receiver
D5R55_RS33725	COG2205	protein histidine kinase activity
D5R55_RS33735	COG1077	Cell shape determining protein MreB Mrl
D5R55_RS33785	COG0642	Histidine kinase
D5R55_RS33830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D5R55_RS33840	COG2070	2-Nitropropane dioxygenase
D5R55_RS33850	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D5R55_RS33890	COG2197	response regulator
D5R55_RS33900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D5R55_RS33925	COG2814	Major facilitator Superfamily
D5R55_RS33940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D5R55_RS33955	COG2070	2-Nitropropane dioxygenase
D5R55_RS33965	COG1960	acyl-CoA dehydrogenase activity
D5R55_RS33970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS33980	COG0174	glutamine synthetase
D5R55_RS34010	COG1051	belongs to the nudix hydrolase family
D5R55_RS34010	COG1056	cytidyltransferase-related domain
D5R55_RS34020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5R55_RS34025	COG0697	spore germination
D5R55_RS34035	COG0583	DNA-binding transcription factor activity
D5R55_RS34050	COG0546	phosphoglycolate phosphatase activity
D5R55_RS34055	COG4115	mRNA cleavage
D5R55_RS34080	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D5R55_RS34100	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D5R55_RS34105	COG3214	Protein conserved in bacteria
D5R55_RS34115	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D5R55_RS34120	COG0477	Major facilitator Superfamily
D5R55_RS34125	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
D5R55_RS34155	COG4789	Type iii secretion
D5R55_RS34160	COG4794	Type iii secretion
D5R55_RS34165	COG1450	Type ii and iii secretion system protein
D5R55_RS34210	COG1684	flagellar biosynthetic protein fliR
D5R55_RS34215	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D5R55_RS34250	COG0745	RESPONSE REGULATOR receiver
D5R55_RS34270	COG2207	Transcriptional regulator
D5R55_RS34310	COG2204	response regulator
D5R55_RS34335	COG0840	transmembrane signaling receptor activity
D5R55_RS34340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D5R55_RS34350	COG1879	ABC-type sugar transport system periplasmic component
D5R55_RS34360	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5R55_RS34365	COG1063	alcohol dehydrogenase
D5R55_RS34370	COG1070	Carbohydrate kinase
D5R55_RS34400	COG3128	pkhd-type hydroxylase
D5R55_RS34425	COG0540	Belongs to the ATCase OTCase family
D5R55_RS34455	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS34470	COG0745	RESPONSE REGULATOR receiver
D5R55_RS34475	COG2205	protein histidine kinase activity
D5R55_RS34480	COG4452	Inner membrane protein CreD
D5R55_RS34495	COG0477	Major facilitator Superfamily
D5R55_RS34545	COG2321	neutral zinc metallopeptidase
D5R55_RS34555	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS34590	COG1175	transmembrane transport
D5R55_RS34620	COG1902	pentaerythritol trinitrate reductase activity
D5R55_RS34635	COG0546	phosphoglycolate phosphatase activity
D5R55_RS34655	COG0604	alcohol dehydrogenase
D5R55_RS34655	COG3321	synthase
D5R55_RS34680	COG1176	ABC-type spermidine putrescine transport system, permease component I
D5R55_RS34685	COG1116	anion transmembrane transporter activity
D5R55_RS34700	COG1301	dicarboxylic acid transport
D5R55_RS34710	COG1252	NADH dehydrogenase
D5R55_RS34715	COG1309	transcriptional regulator
D5R55_RS34720	COG0583	DNA-binding transcription factor activity
D5R55_RS34725	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS34730	COG0789	Transcriptional regulator
D5R55_RS34775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D5R55_RS34785	COG0516	GMP reductase activity
D5R55_RS34785	COG0517	IMP dehydrogenase activity
D5R55_RS34790	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D5R55_RS34950	COG2197	response regulator
D5R55_RS34955	COG1285	pathogenesis
D5R55_RS34990	COG1408	metallophosphoesterase
D5R55_RS35115	COG0529	Catalyzes the synthesis of activated sulfate
D5R55_RS35155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D5R55_RS35170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D5R55_RS35185	COG1414	Transcriptional regulator
D5R55_RS35190	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS35195	COG2146	nitrite reductase [NAD(P)H] activity
D5R55_RS35210	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS35220	COG2226	methyltransferase
D5R55_RS35220	COG1073	alpha beta
D5R55_RS35225	COG1414	Transcriptional regulator
D5R55_RS35230	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS35235	COG0028	Belongs to the TPP enzyme family
D5R55_RS35245	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS35260	COG0477	Major facilitator Superfamily
D5R55_RS35265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D5R55_RS35270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D5R55_RS35300	COG0154	amidase activity
D5R55_RS35340	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D5R55_RS35345	COG2902	Dehydrogenase
D5R55_RS35350	COG1942	4-Oxalocrotonate Tautomerase
D5R55_RS35370	COG0596	Alpha beta hydrolase
D5R55_RS35395	COG0010	Belongs to the arginase family
D5R55_RS35400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D5R55_RS35410	COG1278	Cold shock
D5R55_RS35430	COG2814	Major facilitator Superfamily
D5R55_RS35435	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS35445	COG0604	alcohol dehydrogenase
D5R55_RS35455	COG0840	transmembrane signaling receptor activity
D5R55_RS35495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D5R55_RS35500	COG0583	DNA-binding transcription factor activity
D5R55_RS35510	COG1012	belongs to the aldehyde dehydrogenase family
D5R55_RS35520	COG1473	amidohydrolase
D5R55_RS35535	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
D5R55_RS35540	COG2271	Major facilitator Superfamily
D5R55_RS35545	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D5R55_RS35550	COG0583	DNA-binding transcription factor activity
D5R55_RS35565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D5R55_RS35580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS35580	COG2198	Histidine kinase
D5R55_RS35580	COG2205	protein histidine kinase activity
D5R55_RS35580	COG0784	Response regulator, receiver
D5R55_RS35675	COG1309	transcriptional regulator
D5R55_RS35680	COG2916	Histone family protein nucleoid-structuring protein H-NS
D5R55_RS35685	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS35715	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS35720	COG0583	DNA-binding transcription factor activity
D5R55_RS35725	COG0667	Aldo Keto reductase
D5R55_RS35760	COG0583	DNA-binding transcription factor activity
D5R55_RS35775	COG3188	usher protein
D5R55_RS35780	COG3121	Chaperone
D5R55_RS35795	COG2261	transglycosylase associated protein
D5R55_RS35800	COG4172	Belongs to the ABC transporter superfamily
D5R55_RS35810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D5R55_RS35815	COG0601	transmembrane transport
D5R55_RS35825	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
D5R55_RS35835	COG2140	Oxalate decarboxylase
D5R55_RS35840	COG1914	H( )-stimulated, divalent metal cation uptake system
D5R55_RS35845	COG4166	transmembrane transport
D5R55_RS35865	COG0243	molybdopterin cofactor binding
D5R55_RS35875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5R55_RS35885	COG0583	DNA-binding transcription factor activity
D5R55_RS35895	COG2814	Major facilitator Superfamily
D5R55_RS35900	COG1335	isochorismatase
D5R55_RS35925	COG0583	DNA-binding transcription factor activity
D5R55_RS35955	COG1404	Belongs to the peptidase S8 family
D5R55_RS35965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS35975	COG2188	Transcriptional regulator
D5R55_RS35990	COG2814	Major facilitator Superfamily
D5R55_RS35995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D5R55_RS36005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D5R55_RS36010	COG2373	Large extracellular alpha-helical protein
D5R55_RS36040	COG2259	Doxx family
D5R55_RS36090	COG1473	amidohydrolase
D5R55_RS36095	COG0583	DNA-binding transcription factor activity
D5R55_RS36120	COG0517	IMP dehydrogenase activity
D5R55_RS36120	COG0516	GMP reductase activity
D5R55_RS36125	COG0583	DNA-binding transcription factor activity
D5R55_RS36130	COG2271	Major facilitator Superfamily
D5R55_RS36135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D5R55_RS36140	COG0583	DNA-binding transcription factor activity
D5R55_RS36155	COG0387	Pfam Sodium calcium exchanger
D5R55_RS36160	COG1250	3-hydroxyacyl-CoA dehydrogenase
D5R55_RS36170	COG1024	Enoyl-CoA hydratase
D5R55_RS36170	COG1250	3-hydroxyacyl-CoA dehydrogenase
D5R55_RS36180	COG0667	Aldo Keto reductase
D5R55_RS36195	COG1063	alcohol dehydrogenase
D5R55_RS36240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D5R55_RS36255	COG0179	Fumarylacetoacetate (FAA) hydrolase
D5R55_RS36265	COG1573	uracil-dna glycosylase
D5R55_RS36270	COG1116	anion transmembrane transporter activity
D5R55_RS36270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D5R55_RS36275	COG3707	response regulator
D5R55_RS36295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D5R55_RS36300	COG2146	nitrite reductase [NAD(P)H] activity
D5R55_RS36305	COG0243	molybdopterin cofactor binding
D5R55_RS36310	COG1028	Short-chain dehydrogenase reductase Sdr
D5R55_RS36335	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D5R55_RS36335	COG0392	lysyltransferase activity
D5R55_RS36355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5R55_RS36360	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D5R55_RS36365	COG3300	MHYT domain
D5R55_RS36365	COG5001	Diguanylate cyclase
D5R55_RS36385	COG1280	lysine exporter protein (LysE YggA)
D5R55_RS36475	COG1278	Cold shock
D5R55_RS36505	COG3511	phospholipase C
D5R55_RS36545	COG1522	sequence-specific DNA binding
D5R55_RS36570	COG4206	TonB-dependent receptor
D5R55_RS36590	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D5R55_RS36605	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
D5R55_RS36625	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
D5R55_RS36630	COG4206	TonB-dependent receptor
D5R55_RS36650	COG1846	Transcriptional regulator
D5R55_RS36660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D5R55_RS36665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS36675	COG1126	abc transporter atp-binding protein
D5R55_RS36680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS36685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5R55_RS36690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS36740	COG3608	succinylglutamate desuccinylase aspartoacylase
D5R55_RS36775	COG2010	Cytochrome c
D5R55_RS36780	COG2885	chlorophyll binding
D5R55_RS36790	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS36825	COG0753	catalase activity
D5R55_RS36840	COG3321	synthase
D5R55_RS36840	COG0604	alcohol dehydrogenase
D5R55_RS36845	COG0113	porphobilinogen synthase activity
D5R55_RS36850	COG1902	pentaerythritol trinitrate reductase activity
D5R55_RS36855	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
D5R55_RS36865	COG0789	Transcriptional regulator
D5R55_RS36905	COG0511	ligase activity, forming carbon-carbon bonds
D5R55_RS36905	COG5016	pyruvate
D5R55_RS36910	COG0511	ligase activity, forming carbon-carbon bonds
D5R55_RS36915	COG0439	Biotin carboxylase
D5R55_RS36925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D5R55_RS36935	COG1309	transcriptional regulator
D5R55_RS36970	COG3012	SEC-C Motif Domain Protein
D5R55_RS36980	COG3621	Patatin-like phospholipase
D5R55_RS37015	COG2130	NADP-dependent
D5R55_RS37020	COG1309	transcriptional regulator
D5R55_RS37050	COG3550	peptidyl-serine autophosphorylation
D5R55_RS37065	COG0477	Major facilitator Superfamily
D5R55_RS37070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D5R55_RS37080	COG1414	Transcriptional regulator
D5R55_RS37135	COG2205	protein histidine kinase activity
D5R55_RS37135	COG2198	Histidine kinase
D5R55_RS37135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5R55_RS37135	COG0784	Response regulator, receiver
D5R55_RS37165	COG1113	amino acid transport
D5R55_RS37235	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
D5R55_RS37240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D5R55_RS37275	COG1522	sequence-specific DNA binding
D5R55_RS37285	COG3511	phospholipase C
D5R55_RS37290	COG1858	cytochrome C peroxidase
D5R55_RS37295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D5R55_RS37300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5R55_RS37310	COG0765	amino acid transport
D5R55_RS37370	COG0038	chloride channel
D5R55_RS37375	COG0402	S-adenosylhomocysteine deaminase activity
D5R55_RS37385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5R55_RS37395	COG0583	DNA-binding transcription factor activity
D5R55_RS37435	COG2124	cytochrome p450
D5R55_RS37495	COG4221	oxidoreductase activity
D5R55_RS37500	COG2271	Major facilitator Superfamily
D5R55_RS37530	COG1280	lysine exporter protein (LysE YggA)
D5R55_RS37535	COG1238	metal cluster binding
D5R55_RS37540	COG0840	transmembrane signaling receptor activity
D5R55_RS37545	COG0318	PFAM AMP-dependent synthetase and ligase
D5R55_RS37560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family