locus-tag	class	description
WT26_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WT26_RS00460	COG0318	PFAM AMP-dependent synthetase and ligase
WT26_RS00755	COG0840	transmembrane signaling receptor activity
WT26_RS00965	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WT26_RS00970	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WT26_RS00995	COG2894	cell division
WT26_RS01695	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WT26_RS02025	COG1309	transcriptional regulator
WT26_RS02250	COG0318	PFAM AMP-dependent synthetase and ligase
WT26_RS02980	COG0277	FAD linked oxidase domain protein
WT26_RS03300	COG0592	DNA-directed DNA polymerase activity
WT26_RS03320	COG3586	endonuclease activity
WT26_RS03330	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
WT26_RS03385	COG0753	catalase activity
WT26_RS03470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WT26_RS03475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WT26_RS03480	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
WT26_RS03515	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT26_RS03530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WT26_RS03550	COG1987	bacterial-type flagellum assembly
WT26_RS03580	COG1346	cytolysis
WT26_RS03585	COG1380	Effector of murein hydrolase LrgA
WT26_RS03590	COG0583	DNA-binding transcription factor activity
WT26_RS03595	COG2814	Major facilitator Superfamily
WT26_RS03645	COG2165	general secretion pathway protein
WT26_RS03680	COG0523	cobalamin synthesis protein
WT26_RS03690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WT26_RS03690	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
WT26_RS03710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WT26_RS03710	COG0519	Catalyzes the synthesis of GMP from XMP
WT26_RS03715	COG1902	pentaerythritol trinitrate reductase activity
WT26_RS03725	COG0642	Histidine kinase
WT26_RS03745	COG3186	Phenylalanine-4-hydroxylase
WT26_RS03750	COG1522	sequence-specific DNA binding
WT26_RS03770	COG0583	DNA-binding transcription factor activity
WT26_RS03835	COG1192	Involved in chromosome partitioning
WT26_RS03840	COG1475	DNA binding
WT26_RS03845	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WT26_RS03855	COG0356	it plays a direct role in the translocation of protons across the membrane
WT26_RS03870	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WT26_RS03875	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WT26_RS03880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WT26_RS03885	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WT26_RS03905	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WT26_RS03910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WT26_RS03915	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WT26_RS03915	COG0506	proline dehydrogenase activity
WT26_RS03915	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WT26_RS03920	COG0683	leucine binding
WT26_RS03930	COG1960	acyl-CoA dehydrogenase activity
WT26_RS03940	COG0436	Aminotransferase
WT26_RS03945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WT26_RS03950	COG0277	FAD linked oxidase domain protein
WT26_RS03960	COG0789	Transcriptional regulator
WT26_RS03980	COG0668	transmembrane transport
WT26_RS03985	COG0531	amino acid
WT26_RS03990	COG4303	Ethanolamine ammonia lyase large subunit
WT26_RS04000	COG0583	DNA-binding transcription factor activity
WT26_RS04005	COG0477	Major facilitator Superfamily
WT26_RS04010	COG1012	belongs to the aldehyde dehydrogenase family
WT26_RS04030	COG0028	Belongs to the TPP enzyme family
WT26_RS04055	COG1760	l-serine dehydratase
WT26_RS04085	COG0673	inositol 2-dehydrogenase activity
WT26_RS04090	COG0210	DNA helicase
WT26_RS04110	COG0582	viral genome integration into host DNA
WT26_RS04265	COG1683	Conserved Protein
WT26_RS04290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WT26_RS04295	COG4106	trans-aconitate 2-methyltransferase activity
WT26_RS04355	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WT26_RS04375	COG0519	Catalyzes the synthesis of GMP from XMP
WT26_RS04390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WT26_RS04395	COG2916	Histone family protein nucleoid-structuring protein H-NS
WT26_RS04400	COG0438	transferase activity, transferring glycosyl groups
WT26_RS04420	COG1360	Flagellar Motor Protein
WT26_RS04425	COG0745	RESPONSE REGULATOR receiver
WT26_RS04435	COG0835	chemotaxis
WT26_RS04440	COG0840	transmembrane signaling receptor activity
WT26_RS04445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WT26_RS04460	COG0745	RESPONSE REGULATOR receiver
WT26_RS04465	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WT26_RS04480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WT26_RS04485	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WT26_RS04500	COG1191	sigma factor activity
WT26_RS04505	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
WT26_RS04510	COG1950	PFAM Membrane protein of
WT26_RS04515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
WT26_RS04560	COG1522	sequence-specific DNA binding
WT26_RS04570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WT26_RS04590	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WT26_RS04595	COG2823	Periplasmic or secreted lipoprotein
WT26_RS04625	COG0583	DNA-binding transcription factor activity
WT26_RS04645	COG1136	(ABC) transporter
WT26_RS04645	COG0577	efflux transmembrane transporter activity
WT26_RS04665	COG2084	Dehydrogenase
WT26_RS04670	COG1280	lysine exporter protein (LysE YggA)
WT26_RS04675	COG2814	Major facilitator Superfamily
WT26_RS04680	COG0583	DNA-binding transcription factor activity
WT26_RS04700	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WT26_RS04710	COG1881	PFAM PEBP family protein
WT26_RS04715	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WT26_RS04720	COG0280	phosphate acetyltransferase
WT26_RS04720	COG0281	malic enzyme
WT26_RS04745	COG1522	sequence-specific DNA binding
WT26_RS04765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WT26_RS04770	COG2151	metal-sulfur cluster biosynthetic enzyme
WT26_RS04775	COG3396	Phenylacetate-CoA oxygenase
WT26_RS04780	COG3460	Phenylacetate-CoA oxygenase
WT26_RS04785	COG3396	Phenylacetate-CoA oxygenase
WT26_RS04840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WT26_RS04850	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WT26_RS04865	COG0081	regulation of translation
WT26_RS04890	COG0514	ATP-dependent DNA helicase (RecQ)
WT26_RS05005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WT26_RS05015	COG0200	Binds to the 23S rRNA
WT26_RS05020	COG0201	protein transport
WT26_RS05035	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WT26_RS05065	COG4232	protein-disulfide reductase activity
WT26_RS05075	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WT26_RS05085	COG1333	cytochrome c biogenesis protein
WT26_RS05090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WT26_RS05095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WT26_RS05100	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
WT26_RS05150	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WT26_RS05155	COG1653	transport
WT26_RS05160	COG1175	transmembrane transport
WT26_RS05165	COG0395	ABC-type sugar transport system, permease component
WT26_RS05175	COG0584	glycerophosphoryl diester phosphodiesterase
WT26_RS05190	COG0070	glutamate synthase
WT26_RS05190	COG0069	glutamate synthase activity
WT26_RS05190	COG0067	glutamate synthase
WT26_RS05210	COG1115	amino acid carrier protein
WT26_RS05215	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
WT26_RS05220	COG4178	(ABC) transporter
WT26_RS05245	COG1127	ABC transporter
WT26_RS05250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WT26_RS05255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WT26_RS05275	COG1131	(ABC) transporter
WT26_RS05280	COG0842	Transport permease protein
WT26_RS05315	COG2095	MarC family integral membrane protein
WT26_RS05365	COG0805	protein transport
WT26_RS05370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WT26_RS05375	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WT26_RS05380	COG0723	plastoquinol--plastocyanin reductase activity
WT26_RS05385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WT26_RS05395	COG0625	glutathione transferase activity
WT26_RS05400	COG2969	positive regulation of protein catabolic process
WT26_RS05415	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
WT26_RS05460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WT26_RS05530	COG0840	transmembrane signaling receptor activity
WT26_RS05730	COG1309	transcriptional regulator
WT26_RS05745	COG0443	Heat shock 70 kDa protein
WT26_RS05750	COG1278	Cold shock
WT26_RS05755	COG0531	amino acid
WT26_RS05765	COG3384	dioxygenase
WT26_RS05775	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WT26_RS05780	COG2890	protein-(glutamine-N5) methyltransferase activity
WT26_RS05805	COG0006	proline dipeptidase activity
WT26_RS05810	COG1335	isochorismatase
WT26_RS05820	COG0488	(ABC) transporter
WT26_RS05840	COG0012	GTP binding
WT26_RS05845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WT26_RS05850	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WT26_RS05865	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WT26_RS05885	COG0512	Glutamine amidotransferase of anthranilate synthase
WT26_RS05895	COG0546	phosphoglycolate phosphatase activity
WT26_RS05900	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WT26_RS05905	COG2967	ApaG domain
WT26_RS05910	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WT26_RS05920	COG2050	protein possibly involved in aromatic compounds catabolism
WT26_RS05925	COG1024	Enoyl-CoA hydratase
WT26_RS05940	COG1024	Enoyl-CoA hydratase
WT26_RS05970	COG0243	molybdopterin cofactor binding
WT26_RS05975	COG0318	PFAM AMP-dependent synthetase and ligase
WT26_RS05980	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT26_RS05990	COG2001	Belongs to the MraZ family
WT26_RS06000	COG3116	cell division
WT26_RS06010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WT26_RS06015	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WT26_RS06045	COG1181	Belongs to the D-alanine--D-alanine ligase family
WT26_RS06050	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WT26_RS06100	COG0494	nUDIX hydrolase
WT26_RS06105	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
WT26_RS06110	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
WT26_RS06120	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WT26_RS06135	COG4536	flavin adenine dinucleotide binding
WT26_RS06145	COG0142	geranyltranstransferase activity
WT26_RS06185	COG2095	MarC family integral membrane protein
WT26_RS06190	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
WT26_RS06195	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WT26_RS06210	COG3023	N-Acetylmuramoyl-L-alanine amidase
WT26_RS06235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WT26_RS06240	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
WT26_RS06255	COG0439	Biotin carboxylase
WT26_RS06260	COG0511	ligase activity, forming carbon-carbon bonds
WT26_RS06265	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WT26_RS06270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WT26_RS06280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WT26_RS06285	COG3150	esterase
WT26_RS06290	COG0557	exoribonuclease II activity
WT26_RS06295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WT26_RS06315	COG1414	Transcriptional regulator
WT26_RS06330	COG1028	Short-chain dehydrogenase reductase Sdr
WT26_RS06345	COG1028	Short-chain dehydrogenase reductase Sdr
WT26_RS06355	COG0284	orotidine-5'-phosphate decarboxylase activity
WT26_RS06360	COG1546	Belongs to the CinA family
WT26_RS06365	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WT26_RS06380	COG4290	ribonuclease
WT26_RS06395	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WT26_RS06405	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WT26_RS06410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WT26_RS06415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WT26_RS06425	COG0583	DNA-binding transcription factor activity
WT26_RS06430	COG1028	Short-chain dehydrogenase reductase Sdr
WT26_RS06435	COG1063	alcohol dehydrogenase
WT26_RS06440	COG2814	Major facilitator Superfamily
WT26_RS06455	COG1301	dicarboxylic acid transport
WT26_RS06460	COG4266	Belongs to the allantoicase family
WT26_RS06465	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
WT26_RS06470	COG0735	belongs to the Fur family
WT26_RS06475	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WT26_RS06500	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
WT26_RS06505	COG1466	dna polymerase III delta subunit
WT26_RS06515	COG1981	membrane
WT26_RS06530	COG0800	Aldolase
WT26_RS06540	COG3265	gluconokinase activity
WT26_RS06550	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WT26_RS06565	COG0583	DNA-binding transcription factor activity
WT26_RS06570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WT26_RS06580	COG0765	amino acid transport
WT26_RS06585	COG0765	amino acid transport
WT26_RS06590	COG1126	abc transporter atp-binding protein
WT26_RS06595	COG0121	glutamine amidotransferase
WT26_RS06600	COG0418	dihydroorotase activity
WT26_RS06625	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WT26_RS06630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WT26_RS06655	COG0588	phosphoglycerate mutase activity
WT26_RS06685	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
WT26_RS06690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WT26_RS06695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WT26_RS06700	COG0006	proline dipeptidase activity
WT26_RS06705	COG0625	glutathione transferase activity
WT26_RS06710	COG0069	glutamate synthase activity
WT26_RS06715	COG0482	sulfurtransferase activity
WT26_RS06795	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WT26_RS06795	COG3008	intermembrane lipid transfer
WT26_RS06800	COG2995	paraquat-inducible protein a
WT26_RS06815	COG2353	YceI-like domain
WT26_RS06830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WT26_RS06835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WT26_RS06840	COG1862	Preprotein translocase
WT26_RS06845	COG0343	queuine tRNA-ribosyltransferase activity
WT26_RS06855	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WT26_RS06890	COG0247	lactate metabolic process
WT26_RS06895	COG0277	FAD linked oxidase domain protein
WT26_RS06900	COG0277	FAD linked oxidase domain protein
WT26_RS06905	COG0277	FAD linked oxidase domain protein
WT26_RS06910	COG2096	Adenosyltransferase
WT26_RS06915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WT26_RS06915	COG1017	nitric oxide dioxygenase activity
WT26_RS06930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WT26_RS06935	COG0312	modulator of DNA gyrase
WT26_RS06940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WT26_RS06950	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WT26_RS06955	COG0497	DNA recombination
WT26_RS07000	COG0512	Glutamine amidotransferase of anthranilate synthase
WT26_RS07000	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WT26_RS07010	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WT26_RS07020	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WT26_RS07025	COG0617	tRNA 3'-terminal CCA addition
WT26_RS07035	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WT26_RS07040	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WT26_RS07060	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WT26_RS07065	COG0586	Pfam SNARE associated Golgi protein
WT26_RS07080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WT26_RS07095	COG4682	membrane
WT26_RS07105	COG2916	Histone family protein nucleoid-structuring protein H-NS
WT26_RS07110	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WT26_RS07110	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WT26_RS07175	COG0824	Thioesterase
WT26_RS07180	COG4221	oxidoreductase activity
WT26_RS07190	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WT26_RS07235	COG0450	alkyl hydroperoxide reductase
WT26_RS07240	COG1960	acyl-CoA dehydrogenase activity
WT26_RS07260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WT26_RS07270	COG2814	Major facilitator Superfamily
WT26_RS07275	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
WT26_RS07290	COG2814	Major facilitator Superfamily
WT26_RS07295	COG0778	Nitroreductase
WT26_RS07300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WT26_RS07305	COG0583	DNA-binding transcription factor activity
WT26_RS07310	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WT26_RS07315	COG4977	sequence-specific DNA binding
WT26_RS07335	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WT26_RS07365	COG2823	Periplasmic or secreted lipoprotein
WT26_RS07380	COG0730	response to heat
WT26_RS07390	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
WT26_RS07410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WT26_RS07450	COG3842	ATPase activity
WT26_RS07465	COG2837	iron assimilation
WT26_RS07480	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WT26_RS07505	COG1773	rubredoxin
WT26_RS07525	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
WT26_RS07535	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
WT26_RS07575	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WT26_RS07595	COG2755	lipolytic protein G-D-S-L family
WT26_RS07595	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WT26_RS07600	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WT26_RS07600	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WT26_RS07620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WT26_RS07635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WT26_RS07640	COG0438	transferase activity, transferring glycosyl groups
WT26_RS07660	COG0859	PFAM glycosyl transferase family 9
WT26_RS07700	COG0831	urea catabolic process
WT26_RS07715	COG1129	ABC transporter
WT26_RS07725	COG0559	Belongs to the binding-protein-dependent transport system permease family
WT26_RS07735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WT26_RS07745	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WT26_RS07755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WT26_RS07815	COG4948	Mandelate Racemase Muconate Lactonizing
WT26_RS07825	COG0494	nUDIX hydrolase
WT26_RS07835	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
WT26_RS07855	COG0762	integral membrane protein
WT26_RS07890	COG0436	Aminotransferase
WT26_RS07895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WT26_RS07915	COG3706	GGDEF domain
WT26_RS07925	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
WT26_RS07935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WT26_RS07935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WT26_RS07940	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WT26_RS07950	COG2814	Major facilitator Superfamily
WT26_RS07960	COG0363	glucosamine-6-phosphate deaminase activity
WT26_RS07965	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WT26_RS07975	COG1175	transmembrane transport
WT26_RS07980	COG0395	ABC-type sugar transport system, permease component
WT26_RS07985	COG3842	ATPase activity
WT26_RS07990	COG2860	membrane
WT26_RS07995	COG1193	negative regulation of DNA recombination
WT26_RS08000	COG0492	ferredoxin-NADP+ reductase activity
WT26_RS08005	COG1674	ftsk spoiiie
WT26_RS08010	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WT26_RS08015	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WT26_RS08045	COG2826	transposase and inactivated derivatives, IS30 family
WT26_RS08060	COG2755	lipolytic protein G-D-S-L family
WT26_RS08060	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WT26_RS08100	COG5377	YqaJ viral recombinase family
WT26_RS08120	COG0210	DNA helicase
WT26_RS08175	COG0582	viral genome integration into host DNA
WT26_RS08215	COG2894	cell division
WT26_RS08220	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WT26_RS08235	COG0859	PFAM glycosyl transferase family 9
WT26_RS08245	COG0477	Major facilitator Superfamily
WT26_RS08265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WT26_RS08270	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WT26_RS08275	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
WT26_RS08280	COG1561	YicC-like family, N-terminal region
WT26_RS08295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WT26_RS08320	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT26_RS08330	COG1278	Cold shock
WT26_RS08335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WT26_RS08335	COG1199	ATP-dependent helicase activity
WT26_RS08355	COG4772	TonB-dependent receptor
WT26_RS08380	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
WT26_RS08385	COG0583	DNA-binding transcription factor activity
WT26_RS08395	COG0308	aminopeptidase N
WT26_RS08405	COG2119	membrane
WT26_RS08410	COG0402	S-adenosylhomocysteine deaminase activity
WT26_RS08415	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WT26_RS08430	COG0154	amidase activity
WT26_RS08440	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WT26_RS08470	COG3383	formate dehydrogenase (NAD+) activity
WT26_RS08485	COG1910	domain protein
WT26_RS08505	COG0546	phosphoglycolate phosphatase activity
WT26_RS08510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WT26_RS08540	COG0287	Prephenate dehydrogenase
WT26_RS08560	COG0776	regulation of translation
WT26_RS08570	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WT26_RS08595	COG2951	lytic endotransglycosylase activity
WT26_RS08600	COG0123	including yeast histone deacetylase and acetoin utilization protein
WT26_RS08605	COG2267	carboxylic ester hydrolase activity
WT26_RS08615	COG2011	ABC-type metal ion transport system permease component
WT26_RS08620	COG1464	Belongs to the NlpA lipoprotein family
WT26_RS08635	COG1960	acyl-CoA dehydrogenase activity
WT26_RS08685	COG0494	nUDIX hydrolase
WT26_RS08705	COG0501	Belongs to the peptidase M48B family
WT26_RS08715	COG0521	Mo-molybdopterin cofactor biosynthetic process
WT26_RS08720	COG3028	Belongs to the UPF0307 family
WT26_RS08725	COG0312	modulator of DNA gyrase
WT26_RS08730	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
WT26_RS08735	COG2204	response regulator
WT26_RS08750	COG2204	response regulator
WT26_RS08755	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WT26_RS08775	COG0114	fumarate hydratase activity
WT26_RS08785	COG2501	S4 domain
WT26_RS08815	COG3045	CreA protein
WT26_RS08830	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WT26_RS08870	COG0303	'Molybdopterin
WT26_RS08880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WT26_RS08885	COG1530	ribonuclease E activity
WT26_RS08895	COG0546	phosphoglycolate phosphatase activity
WT26_RS08905	COG0616	signal peptide processing
WT26_RS08920	COG1399	metal-binding, possibly nucleic acid-binding protein
WT26_RS08955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WT26_RS08965	COG1595	DNA-templated transcription, initiation
WT26_RS08980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WT26_RS08995	COG0681	Belongs to the peptidase S26 family
WT26_RS09000	COG0571	ribonuclease III activity
WT26_RS09005	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WT26_RS09015	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WT26_RS09025	COG1472	Belongs to the glycosyl hydrolase 3 family
WT26_RS09030	COG2204	response regulator
WT26_RS09075	COG3291	Pkd domain containing protein
WT26_RS09080	COG1956	GAF domain-containing protein
WT26_RS09095	COG2153	protein acetylation
WT26_RS09120	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
WT26_RS09125	COG1132	(ABC) transporter
WT26_RS09130	COG0438	transferase activity, transferring glycosyl groups
WT26_RS09155	COG3511	phospholipase C
WT26_RS09165	COG0596	Alpha beta hydrolase
WT26_RS09170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WT26_RS09180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WT26_RS09185	COG3394	polysaccharide catabolic process
WT26_RS09245	COG2988	succinylglutamate desuccinylase activity
WT26_RS09285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WT26_RS09295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WT26_RS09320	COG3008	intermembrane lipid transfer
WT26_RS09330	COG0004	ammonium transporteR
WT26_RS09345	COG1959	2 iron, 2 sulfur cluster binding
WT26_RS09355	COG0668	transmembrane transport
WT26_RS09360	COG1522	sequence-specific DNA binding
WT26_RS09365	COG3842	ATPase activity
WT26_RS09370	COG1178	ABC-type Fe3 transport system permease component
WT26_RS09375	COG1840	ABC-type Fe3 transport system, periplasmic component
WT26_RS09385	COG1289	transmembrane transporter activity
WT26_RS09390	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WT26_RS09395	COG1074	ATP-dependent DNA helicase activity
WT26_RS09400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WT26_RS09410	COG2200	EAL domain
WT26_RS09440	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
WT26_RS09445	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WT26_RS09450	COG0840	transmembrane signaling receptor activity
WT26_RS09465	COG0697	spore germination
WT26_RS09470	COG2814	Major facilitator Superfamily
WT26_RS09475	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WT26_RS09480	COG3842	ATPase activity
WT26_RS09485	COG1177	transmembrane transport
WT26_RS09495	COG1840	ABC-type Fe3 transport system, periplasmic component
WT26_RS09500	COG1609	Transcriptional regulator
WT26_RS09525	COG0753	catalase activity
WT26_RS09530	COG0840	transmembrane signaling receptor activity
WT26_RS09535	COG0583	DNA-binding transcription factor activity
WT26_RS09550	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WT26_RS09555	COG2814	Major facilitator Superfamily
WT26_RS09560	COG0583	DNA-binding transcription factor activity
WT26_RS09575	COG0583	DNA-binding transcription factor activity
WT26_RS09580	COG1253	flavin adenine dinucleotide binding
WT26_RS09600	COG1250	3-hydroxyacyl-CoA dehydrogenase
WT26_RS09610	COG0583	DNA-binding transcription factor activity
WT26_RS09630	COG3052	prosthetic group binding
WT26_RS09650	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
WT26_RS09695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WT26_RS09705	COG2226	methyltransferase
WT26_RS09710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WT26_RS09715	COG0741	lytic transglycosylase activity
WT26_RS09715	COG1388	LysM domain
WT26_RS09720	COG2223	nitrite transmembrane transporter activity
WT26_RS09725	COG0505	Belongs to the CarA family
WT26_RS09735	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WT26_RS09740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WT26_RS09750	COG1534	Rna-binding protein
WT26_RS09760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WT26_RS09775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WT26_RS09780	COG0573	inorganic phosphate transmembrane transporter activity
WT26_RS09785	COG0581	inorganic phosphate transmembrane transporter activity
WT26_RS09800	COG0745	RESPONSE REGULATOR receiver
WT26_RS09840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WT26_RS09860	COG2986	histidine ammonia-lyase
WT26_RS09880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WT26_RS09890	COG1028	Short-chain dehydrogenase reductase Sdr
WT26_RS09895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WT26_RS09950	COG0534	Mate efflux family protein
WT26_RS09960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WT26_RS09965	COG4942	peptidase
WT26_RS09990	COG5001	Diguanylate cyclase
WT26_RS10005	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
WT26_RS10010	COG2916	Histone family protein nucleoid-structuring protein H-NS
WT26_RS10025	COG1176	ABC-type spermidine putrescine transport system, permease component I
WT26_RS10030	COG1177	transmembrane transport
WT26_RS10040	COG0583	DNA-binding transcription factor activity
WT26_RS10055	COG2916	Histone family protein nucleoid-structuring protein H-NS
WT26_RS10070	COG1695	Transcriptional regulator
WT26_RS10075	COG1902	pentaerythritol trinitrate reductase activity
WT26_RS10075	COG0446	pyridine nucleotide-disulphide oxidoreductase
WT26_RS10090	COG0745	RESPONSE REGULATOR receiver
WT26_RS10115	COG1595	DNA-templated transcription, initiation
WT26_RS10125	COG4774	siderophore transport
WT26_RS10135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WT26_RS10155	COG4589	Belongs to the CDS family
WT26_RS10165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WT26_RS10170	COG2267	carboxylic ester hydrolase activity
WT26_RS10175	COG2453	phosphatase
WT26_RS10175	COG0671	phosphoesterase, PA-phosphatase related
WT26_RS10185	COG5001	Diguanylate cyclase
WT26_RS10190	COG1215	transferase activity, transferring glycosyl groups
WT26_RS10195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
WT26_RS10225	COG2194	sulfuric ester hydrolase activity
WT26_RS10235	COG1741	Belongs to the pirin family
WT26_RS10245	COG0025	NhaP-type Na H and K H
WT26_RS10260	COG0583	DNA-binding transcription factor activity
WT26_RS10270	COG1574	metal-dependent hydrolase with the TIM-barrel fold
WT26_RS10305	COG1858	cytochrome C peroxidase
WT26_RS10315	COG1051	belongs to the nudix hydrolase family
WT26_RS10325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WT26_RS10355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WT26_RS10370	COG0477	Major facilitator Superfamily
WT26_RS10375	COG2816	NAD+ diphosphatase activity
WT26_RS10380	COG0824	Thioesterase
WT26_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
WT26_RS10410	COG3718	enzyme involved in inositol metabolism
WT26_RS10420	COG3962	Belongs to the TPP enzyme family
WT26_RS10425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WT26_RS10430	COG1129	ABC transporter
WT26_RS10435	COG1172	Belongs to the binding-protein-dependent transport system permease family
WT26_RS10450	COG0673	inositol 2-dehydrogenase activity
WT26_RS10455	COG0673	inositol 2-dehydrogenase activity
WT26_RS10460	COG0425	Belongs to the sulfur carrier protein TusA family
WT26_RS10470	COG0745	RESPONSE REGULATOR receiver
WT26_RS10480	COG5002	protein histidine kinase activity
WT26_RS10490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WT26_RS10495	COG0525	valine-tRNA ligase activity
WT26_RS10510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WT26_RS10515	COG2223	nitrite transmembrane transporter activity
WT26_RS10520	COG0840	transmembrane signaling receptor activity
WT26_RS10545	COG0583	DNA-binding transcription factor activity
WT26_RS10555	COG0277	FAD linked oxidase domain protein
WT26_RS10570	COG1295	ribonuclease BN
WT26_RS10585	COG0477	Major facilitator Superfamily
WT26_RS10600	COG1028	Short-chain dehydrogenase reductase Sdr
WT26_RS10640	COG0251	oxidation-reduction process
WT26_RS10645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WT26_RS10660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WT26_RS10675	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WT26_RS10685	COG0776	regulation of translation
WT26_RS10705	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WT26_RS10705	COG2755	lipolytic protein G-D-S-L family
WT26_RS10710	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WT26_RS10715	COG3344	reverse transcriptase
WT26_RS10755	COG0583	DNA-binding transcription factor activity
WT26_RS10760	COG0436	Aminotransferase
WT26_RS10765	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WT26_RS10770	COG1187	pseudouridine synthase activity
WT26_RS10775	COG0779	Required for maturation of 30S ribosomal subunits
WT26_RS10780	COG0195	Participates in both transcription termination and antitermination
WT26_RS10780	COG2251	uridine kinase activity
WT26_RS10785	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WT26_RS10800	COG2814	Major facilitator Superfamily
WT26_RS10815	COG1846	Transcriptional regulator
WT26_RS10820	COG1217	gtp-binding protein TYPA
WT26_RS10825	COG0567	Dehydrogenase, E1 component
WT26_RS10830	COG0508	dehydrogenase complex catalyzes the overall conversion of
WT26_RS10835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WT26_RS10840	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WT26_RS10890	COG4964	Belongs to the GSP D family
WT26_RS10950	COG0318	PFAM AMP-dependent synthetase and ligase
WT26_RS10960	COG2814	Major facilitator Superfamily
WT26_RS10985	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WT26_RS10995	COG1879	ABC-type sugar transport system periplasmic component
WT26_RS11000	COG1172	Belongs to the binding-protein-dependent transport system permease family
WT26_RS11020	COG1120	ATPase activity
WT26_RS11025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WT26_RS11030	COG2819	hydrolase of the alpha beta superfamily
WT26_RS11045	COG4771	TonB-dependent receptor
WT26_RS11055	COG1021	2,3-dihydroxybenzoate-AMP ligase
WT26_RS11060	COG3433	isochorismatase activity
WT26_RS11060	COG1535	isochorismatase
WT26_RS11070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WT26_RS11070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WT26_RS11075	COG1028	Short-chain dehydrogenase reductase Sdr
WT26_RS11080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WT26_RS11105	COG0557	exoribonuclease II activity
WT26_RS11110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WT26_RS11115	COG0318	PFAM AMP-dependent synthetase and ligase
WT26_RS11120	COG3023	N-Acetylmuramoyl-L-alanine amidase
WT26_RS11130	COG1802	Transcriptional regulator
WT26_RS11140	COG0765	amino acid transport
WT26_RS11145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WT26_RS11150	COG0167	dihydroorotate dehydrogenase activity
WT26_RS11200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WT26_RS11225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WT26_RS11250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WT26_RS11250	COG2755	lipolytic protein G-D-S-L family
WT26_RS11310	COG0667	Aldo Keto reductase
WT26_RS11330	COG0583	DNA-binding transcription factor activity
WT26_RS11335	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
WT26_RS11340	COG0701	Predicted permease
WT26_RS11380	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WT26_RS11385	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WT26_RS11390	COG4208	sulfate ABC transporter
WT26_RS11395	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WT26_RS11400	COG0583	DNA-binding transcription factor activity
WT26_RS11405	COG1879	ABC-type sugar transport system periplasmic component
WT26_RS11410	COG1129	ABC transporter
WT26_RS11415	COG1172	Belongs to the binding-protein-dependent transport system permease family
WT26_RS11420	COG1609	Transcriptional regulator
WT26_RS11425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WT26_RS11430	COG0840	transmembrane signaling receptor activity
WT26_RS11435	COG2766	serine protein kinase
WT26_RS11440	COG2718	Belongs to the UPF0229 family
WT26_RS11445	COG2719	SpoVR family
WT26_RS11450	COG0477	Major facilitator Superfamily
WT26_RS11460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WT26_RS11470	COG0765	amino acid transport
WT26_RS11475	COG0739	heme binding
WT26_RS11480	COG1309	transcriptional regulator
WT26_RS11485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WT26_RS11490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WT26_RS11515	COG3121	Chaperone
WT26_RS11540	COG2175	clavaminate synthase activity
WT26_RS11585	COG3486	L-lysine 6-monooxygenase (NADPH) activity
WT26_RS11590	COG4774	siderophore transport
WT26_RS11615	COG1473	amidohydrolase
WT26_RS11640	COG2814	Major facilitator Superfamily
WT26_RS11650	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
WT26_RS11685	COG0596	Alpha beta hydrolase
WT26_RS11735	COG3979	chitinase
WT26_RS11780	COG2807	transmembrane transport
WT26_RS11785	COG1846	Transcriptional regulator
WT26_RS11790	COG0625	glutathione transferase activity
WT26_RS11815	COG2175	clavaminate synthase activity
WT26_RS11820	COG3246	L-lysine catabolic process to acetate
WT26_RS11825	COG2271	Major facilitator Superfamily
WT26_RS11840	COG3842	ATPase activity
WT26_RS11845	COG1176	ABC-type spermidine putrescine transport system, permease component I
WT26_RS11870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WT26_RS11875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WT26_RS11880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WT26_RS11915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WT26_RS11920	COG2271	Major facilitator Superfamily
WT26_RS11925	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WT26_RS11930	COG1690	Belongs to the RtcB family
WT26_RS11935	COG1902	pentaerythritol trinitrate reductase activity
WT26_RS11940	COG0656	L-ascorbic acid biosynthetic process
WT26_RS11950	COG2814	Major facilitator Superfamily
WT26_RS11970	COG3268	Saccharopine dehydrogenase
WT26_RS11980	COG1846	Transcriptional regulator
WT26_RS11990	COG1764	response to oxidative stress
WT26_RS11995	COG0583	DNA-binding transcription factor activity
WT26_RS12000	COG2010	Cytochrome c
WT26_RS12000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WT26_RS12005	COG2080	2 iron, 2 sulfur cluster binding
WT26_RS12010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WT26_RS12010	COG2010	Cytochrome c
WT26_RS12015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WT26_RS12020	COG0625	glutathione transferase activity
WT26_RS12025	COG0625	glutathione transferase activity
WT26_RS12055	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WT26_RS12060	COG2801	Transposase and inactivated derivatives
WT26_RS12070	COG2837	iron assimilation
WT26_RS12080	COG0243	molybdopterin cofactor binding
WT26_RS12085	COG3781	membrane
WT26_RS12090	COG1294	oxidase, subunit
WT26_RS12095	COG1271	oxidase subunit
WT26_RS12100	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WT26_RS12105	COG0303	'Molybdopterin
WT26_RS12110	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WT26_RS12150	COG0598	Magnesium transport protein CorA
WT26_RS12175	COG2826	transposase and inactivated derivatives, IS30 family
WT26_RS12180	COG1404	Belongs to the peptidase S8 family
WT26_RS12220	COG1609	Transcriptional regulator
WT26_RS12235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WT26_RS12250	COG2855	membrane
WT26_RS12255	COG0038	chloride channel
WT26_RS12295	COG3655	Transcriptional regulator
WT26_RS12320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WT26_RS12320	COG0730	response to heat
WT26_RS12330	COG1177	transmembrane transport
WT26_RS12335	COG1176	ABC-type spermidine putrescine transport system, permease component I
WT26_RS12340	COG3842	ATPase activity
WT26_RS12345	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WT26_RS12355	COG3047	cAMP biosynthetic process
WT26_RS12360	COG2070	2-Nitropropane dioxygenase
WT26_RS12385	COG2205	protein histidine kinase activity
WT26_RS12385	COG2202	Pas domain
WT26_RS12425	COG0488	(ABC) transporter
WT26_RS12505	COG2204	response regulator
WT26_RS12530	COG2801	Transposase and inactivated derivatives
WT26_RS12540	COG0488	(ABC) transporter
WT26_RS12545	COG2982	Protein involved in outer membrane biogenesis
WT26_RS12550	COG1122	ATPase activity
WT26_RS12555	COG0390	transport system, permease component
WT26_RS12575	COG0583	DNA-binding transcription factor activity
WT26_RS12580	COG0560	Phosphoserine phosphatase
WT26_RS12585	COG0626	cystathionine gamma-synthase activity
WT26_RS12605	COG2376	Dihydroxyacetone kinase
WT26_RS12610	COG0612	Peptidase, M16
WT26_RS12630	COG1028	Short-chain dehydrogenase reductase Sdr
WT26_RS12635	COG0183	Belongs to the thiolase family
WT26_RS12640	COG3243	poly(R)-hydroxyalkanoic acid synthase
WT26_RS12650	COG0564	pseudouridine synthase activity
WT26_RS12660	COG1199	ATP-dependent helicase activity
WT26_RS12675	COG2183	response to ionizing radiation
WT26_RS12685	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
WT26_RS12705	COG0330	HflC and HflK could
WT26_RS12710	COG0330	HflC and HflK could
WT26_RS12715	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WT26_RS12730	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WT26_RS12745	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
WT26_RS12755	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WT26_RS12765	COG0670	Belongs to the BI1 family
WT26_RS12805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WT26_RS12820	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WT26_RS12835	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WT26_RS12845	COG0477	Major facilitator Superfamily
WT26_RS12855	COG0254	rRNA binding
WT26_RS12865	COG0534	Mate efflux family protein
WT26_RS12890	COG0542	response to heat
WT26_RS12895	COG1959	2 iron, 2 sulfur cluster binding
WT26_RS12900	COG2346	COG2346, Truncated hemoglobins
WT26_RS12905	COG0314	molybdopterin synthase activity
WT26_RS12910	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WT26_RS12930	COG0436	Aminotransferase
WT26_RS12940	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WT26_RS12945	COG2076	Multidrug Resistance protein
WT26_RS12950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WT26_RS12955	COG0463	Glycosyl transferase, family 2
WT26_RS12965	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WT26_RS12965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WT26_RS12970	COG0726	polysaccharide deacetylase
WT26_RS12975	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WT26_RS12980	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WT26_RS12985	COG0791	NLP P60 protein
WT26_RS12990	COG3344	reverse transcriptase
WT26_RS12995	COG0306	phosphate transporter
WT26_RS13005	COG0305	Participates in initiation and elongation during chromosome replication
WT26_RS13020	COG2965	DNA replication, synthesis of RNA primer
WT26_RS13025	COG0360	Binds together with S18 to 16S ribosomal RNA
WT26_RS13040	COG0583	DNA-binding transcription factor activity
WT26_RS13045	COG3960	tartronate-semialdehyde synthase activity
WT26_RS13050	COG3622	Belongs to the hyi family
WT26_RS13055	COG2084	Dehydrogenase
WT26_RS13060	COG1652	LysM domain
WT26_RS13065	COG0252	asparaginase activity
WT26_RS13085	COG0438	transferase activity, transferring glycosyl groups
WT26_RS13110	COG0084	hydrolase, TatD family'
WT26_RS13125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WT26_RS13140	COG2153	protein acetylation
WT26_RS13145	COG0657	acetylesterase activity
WT26_RS13150	COG2130	NADP-dependent
WT26_RS13175	COG0183	Belongs to the thiolase family
WT26_RS13180	COG1335	isochorismatase
WT26_RS13190	COG0318	PFAM AMP-dependent synthetase and ligase
WT26_RS13200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WT26_RS13215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WT26_RS13225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WT26_RS13225	COG0047	phosphoribosylformylglycinamidine synthase activity
WT26_RS13230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WT26_RS13245	COG4181	ATPase activity
WT26_RS13275	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WT26_RS13290	COG0544	peptidyl-prolyl cis-trans isomerase activity
WT26_RS13305	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WT26_RS13365	COG3385	transposase activity
WT26_RS13385	COG0582	viral genome integration into host DNA
WT26_RS13430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WT26_RS13440	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WT26_RS13445	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WT26_RS13450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WT26_RS13480	COG1970	mechanosensitive ion channel activity
WT26_RS13495	COG3360	Dodecin
WT26_RS13510	COG2351	hydroxyisourate hydrolase activity
WT26_RS13525	COG0583	DNA-binding transcription factor activity
WT26_RS13545	COG4266	Belongs to the allantoicase family
WT26_RS13565	COG1953	Uracil, thiamine, allantoin
WT26_RS13575	COG1619	proteins homologs of microcin C7 resistance protein MccF
WT26_RS13580	COG0590	tRNA wobble adenosine to inosine editing
WT26_RS13605	COG4221	oxidoreductase activity
WT26_RS13630	COG4942	peptidase
WT26_RS13705	COG0697	spore germination
WT26_RS13725	COG0330	HflC and HflK could
WT26_RS13745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WT26_RS13775	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
WT26_RS13785	COG0750	zinc metalloprotease
WT26_RS13800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WT26_RS13815	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WT26_RS13820	COG0052	Belongs to the universal ribosomal protein uS2 family
WT26_RS13825	COG0024	Methionine aminopeptidase
WT26_RS13835	COG1187	pseudouridine synthase activity
WT26_RS13840	COG0242	peptide deformylase activity
WT26_RS13875	COG1393	Belongs to the ArsC family
WT26_RS13885	COG2890	protein-(glutamine-N5) methyltransferase activity
WT26_RS13895	COG0386	Belongs to the glutathione peroxidase family
WT26_RS13900	COG0488	(ABC) transporter
WT26_RS13925	COG0351	phosphomethylpyrimidine kinase
WT26_RS13935	COG1573	uracil-dna glycosylase
WT26_RS13945	COG1214	PFAM Peptidase M22, glycoprotease
WT26_RS13955	COG0513	Belongs to the DEAD box helicase family
WT26_RS13960	COG2224	Isocitrate lyase
WT26_RS13970	COG0583	DNA-binding transcription factor activity
WT26_RS13980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WT26_RS13990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WT26_RS14045	COG1752	Esterase of the alpha-beta hydrolase superfamily
WT26_RS14050	COG0791	NLP P60 protein
WT26_RS14055	COG4172	Belongs to the ABC transporter superfamily
WT26_RS14060	COG4239	(ABC) transporter, permease
WT26_RS14065	COG4174	ABC transporter (Permease)
WT26_RS14105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WT26_RS14110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WT26_RS14115	COG1120	ATPase activity
WT26_RS14120	COG4774	siderophore transport
WT26_RS14125	COG0582	viral genome integration into host DNA
WT26_RS14195	COG0629	single-stranded DNA binding
WT26_RS14315	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
WT26_RS14375	COG2003	Belongs to the UPF0758 family
WT26_RS14400	COG1858	cytochrome C peroxidase
WT26_RS14420	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT26_RS14425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WT26_RS14440	COG1177	transmembrane transport
WT26_RS14450	COG3842	ATPase activity
WT26_RS14540	COG1196	nuclear chromosome segregation
WT26_RS14555	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WT26_RS14565	COG0527	aspartate kinase activity
WT26_RS14570	COG0037	tRNA processing
WT26_RS14595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WT26_RS14605	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WT26_RS14610	COG1045	serine acetyltransferase
WT26_RS14615	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
WT26_RS14620	COG0483	inositol monophosphate 1-phosphatase activity
WT26_RS14630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WT26_RS14635	COG2211	Major facilitator Superfamily
WT26_RS14645	COG2826	transposase and inactivated derivatives, IS30 family
WT26_RS14665	COG2850	peptidyl-arginine hydroxylation
WT26_RS14670	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
WT26_RS14675	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WT26_RS14680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WT26_RS14690	COG0180	Tryptophanyl-tRNA synthetase
WT26_RS14695	COG1994	Peptidase M50
WT26_RS14700	COG0009	L-threonylcarbamoyladenylate synthase
WT26_RS14705	COG0613	PHP domain protein
WT26_RS14710	COG0596	Alpha beta hydrolase
WT26_RS14715	COG2833	Protein of unknown function (DUF455)
WT26_RS14725	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WT26_RS14735	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WT26_RS14745	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WT26_RS14760	COG0658	competence protein
WT26_RS14760	COG2333	competence protein COMEC
WT26_RS14765	COG0084	hydrolase, TatD family'
WT26_RS14785	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WT26_RS14790	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WT26_RS14795	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WT26_RS14800	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WT26_RS14825	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WT26_RS14830	COG0316	Belongs to the HesB IscA family
WT26_RS14835	COG0822	iron-sulfur transferase activity
WT26_RS14840	COG1104	cysteine desulfurase activity
WT26_RS14850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WT26_RS14870	COG1414	Transcriptional regulator
WT26_RS14885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WT26_RS14890	COG0508	dehydrogenase complex catalyzes the overall conversion of
WT26_RS14895	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WT26_RS14905	COG4566	intracellular signal transduction
WT26_RS14910	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WT26_RS14920	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WT26_RS14925	COG1794	racemase activity, acting on amino acids and derivatives
WT26_RS14940	COG1505	serine-type exopeptidase activity
WT26_RS14955	COG0174	glutamine synthetase
WT26_RS14965	COG1546	Belongs to the CinA family
WT26_RS14965	COG1058	Belongs to the CinA family
WT26_RS14985	COG1643	Atp-dependent helicase
WT26_RS14990	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WT26_RS14990	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WT26_RS15000	COG0477	Major facilitator Superfamily
WT26_RS15010	COG1960	acyl-CoA dehydrogenase activity
WT26_RS15015	COG0583	DNA-binding transcription factor activity
WT26_RS15045	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WT26_RS15055	COG0174	glutamine synthetase
WT26_RS15060	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WT26_RS15090	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
WT26_RS15100	COG2986	histidine ammonia-lyase
WT26_RS15180	COG0438	transferase activity, transferring glycosyl groups
WT26_RS15200	COG2165	general secretion pathway protein
WT26_RS15240	COG1459	type II secretion system
WT26_RS15250	COG2197	response regulator
WT26_RS15270	COG1196	nuclear chromosome segregation
WT26_RS15270	COG0741	lytic transglycosylase activity
WT26_RS15270	COG0739	heme binding
WT26_RS15280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WT26_RS15335	COG2310	stress, protein
WT26_RS15345	COG2304	oxidoreductase activity
WT26_RS15375	COG2826	transposase and inactivated derivatives, IS30 family
WT26_RS15400	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WT26_RS15435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WT26_RS15485	COG0672	)-iron permease
WT26_RS15490	COG4633	Protein conserved in bacteria
WT26_RS15500	COG0556	nucleotide-excision repair
WT26_RS15510	COG1028	Short-chain dehydrogenase reductase Sdr
WT26_RS15515	COG0667	Aldo Keto reductase
WT26_RS15520	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WT26_RS15530	COG0789	Transcriptional regulator
WT26_RS15580	COG2866	Carboxypeptidase
WT26_RS15595	COG0436	Aminotransferase
WT26_RS15600	COG0625	glutathione transferase activity
WT26_RS15605	COG1024	Enoyl-CoA hydratase
WT26_RS15610	COG0625	glutathione transferase activity
WT26_RS15625	COG1960	acyl-CoA dehydrogenase activity
WT26_RS15630	COG1960	acyl-CoA dehydrogenase activity
WT26_RS15640	COG0494	nUDIX hydrolase
WT26_RS15650	COG1007	ATP synthesis coupled electron transport
WT26_RS15680	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WT26_RS15685	COG1034	ATP synthesis coupled electron transport
WT26_RS15685	COG1034	ATP synthesis coupled electron transport
WT26_RS15695	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WT26_RS15730	COG0149	triose-phosphate isomerase activity
WT26_RS15735	COG0604	alcohol dehydrogenase
WT26_RS15735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WT26_RS15735	COG3321	synthase
WT26_RS15735	COG4221	oxidoreductase activity
WT26_RS15750	COG0683	leucine binding
WT26_RS15760	COG0288	reversible hydration of carbon dioxide
WT26_RS15765	COG0659	secondary active sulfate transmembrane transporter activity
WT26_RS15775	COG1183	phosphatidylcholine synthase activity
WT26_RS15785	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
WT26_RS15795	COG0028	Belongs to the TPP enzyme family
WT26_RS15825	COG0438	transferase activity, transferring glycosyl groups
WT26_RS15845	COG1028	Short-chain dehydrogenase reductase Sdr
WT26_RS15850	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WT26_RS15860	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WT26_RS15890	COG0745	RESPONSE REGULATOR receiver
WT26_RS15895	COG2205	protein histidine kinase activity
WT26_RS15905	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
WT26_RS15910	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
WT26_RS15930	COG1028	Short-chain dehydrogenase reductase Sdr
WT26_RS15935	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WT26_RS15945	COG0151	Belongs to the GarS family
WT26_RS15960	COG0799	negative regulation of ribosome biogenesis
WT26_RS15965	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WT26_RS15975	COG1530	ribonuclease E activity
WT26_RS15985	COG3171	Protein conserved in bacteria
WT26_RS16025	COG0463	Glycosyl transferase, family 2
WT26_RS16040	COG0859	PFAM glycosyl transferase family 9
WT26_RS16060	COG0513	Belongs to the DEAD box helicase family
WT26_RS16065	COG3895	Periplasmic Protein
WT26_RS16080	COG1674	ftsk spoiiie
WT26_RS16085	COG2706	6-phosphogluconolactonase activity
WT26_RS16090	COG3387	PFAM Glycoside hydrolase 15-related
WT26_RS16100	COG1309	transcriptional regulator
WT26_RS16105	COG2878	Part of a membrane complex involved in electron transport
WT26_RS16110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WT26_RS16145	COG3135	benzoate transporter
WT26_RS16185	COG4804	nuclease activity
WT26_RS16225	COG0697	spore germination
WT26_RS16230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WT26_RS16240	COG0384	phenazine biosynthesis protein PhzF
WT26_RS16260	COG0583	DNA-binding transcription factor activity
WT26_RS16280	COG0488	(ABC) transporter
WT26_RS16290	COG1773	rubredoxin
WT26_RS16345	COG4574	serine-type endopeptidase inhibitor activity
WT26_RS16365	COG2814	Major facilitator Superfamily
WT26_RS16395	COG1116	anion transmembrane transporter activity
WT26_RS16400	COG1176	ABC-type spermidine putrescine transport system, permease component I
WT26_RS16425	COG1741	Belongs to the pirin family
WT26_RS16480	COG2827	Endonuclease containing a URI domain
WT26_RS16485	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WT26_RS16500	COG2271	Major facilitator Superfamily
WT26_RS16520	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WT26_RS16525	COG2226	methyltransferase
WT26_RS16550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WT26_RS16575	COG0489	protein tyrosine kinase activity
WT26_RS16625	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
WT26_RS16645	COG2259	Doxx family
WT26_RS16650	COG1492	cobalamin metabolic process
WT26_RS16660	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
WT26_RS16670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WT26_RS16680	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
WT26_RS16685	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
WT26_RS16690	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
WT26_RS16695	COG4139	cobalamin transport
WT26_RS16700	COG4206	TonB-dependent receptor
WT26_RS16735	COG0583	DNA-binding transcription factor activity
WT26_RS16745	COG4654	Cytochrome c, class I
WT26_RS16780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WT26_RS16780	COG1648	precorrin-2 dehydrogenase activity
WT26_RS16785	COG2895	sulfate adenylyltransferase (ATP) activity
WT26_RS16810	COG0583	DNA-binding transcription factor activity
WT26_RS16820	COG0583	DNA-binding transcription factor activity
WT26_RS16825	COG4221	oxidoreductase activity
WT26_RS16840	COG1187	pseudouridine synthase activity
WT26_RS16850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WT26_RS16860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WT26_RS16865	COG0456	acetyltransferase
WT26_RS16900	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WT26_RS16905	COG1047	Peptidyl-prolyl cis-trans
WT26_RS16925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WT26_RS16945	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
WT26_RS16945	COG3264	Mechanosensitive ion channel
WT26_RS16950	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WT26_RS16950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WT26_RS16955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WT26_RS16960	COG0196	riboflavin kinase activity
WT26_RS16970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WT26_RS16975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WT26_RS16990	COG1113	amino acid transport
WT26_RS16995	COG0542	response to heat
WT26_RS17005	COG1278	Cold shock
WT26_RS17010	COG5295	Hep Hag repeat protein
WT26_RS17040	COG1187	pseudouridine synthase activity
WT26_RS17055	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
WT26_RS17065	COG0656	L-ascorbic acid biosynthetic process
WT26_RS17070	COG2188	Transcriptional regulator
WT26_RS17075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WT26_RS17090	COG2814	Major facilitator Superfamily
WT26_RS17120	COG2271	Major facilitator Superfamily
WT26_RS17125	COG2271	Major facilitator Superfamily
WT26_RS17130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WT26_RS17135	COG1570	exodeoxyribonuclease VII activity
WT26_RS17150	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WT26_RS17170	COG0728	peptidoglycan biosynthetic process
WT26_RS17205	COG1666	GTP binding
WT26_RS17220	COG0318	PFAM AMP-dependent synthetase and ligase
WT26_RS17225	COG4974	Belongs to the 'phage' integrase family
WT26_RS17235	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WT26_RS17240	COG0802	atpase or kinase
WT26_RS17245	COG0860	N-Acetylmuramoyl-L-alanine amidase
WT26_RS17255	COG1741	Belongs to the pirin family
WT26_RS17265	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WT26_RS17275	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WT26_RS17295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WT26_RS17310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WT26_RS17315	COG1522	sequence-specific DNA binding
WT26_RS17340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WT26_RS17345	COG1012	belongs to the aldehyde dehydrogenase family
WT26_RS17360	COG0246	Mannitol dehydrogenase
WT26_RS17365	COG1070	Carbohydrate kinase
WT26_RS17385	COG0583	DNA-binding transcription factor activity
WT26_RS17390	COG3842	ATPase activity
WT26_RS17395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WT26_RS17405	COG4209	transmembrane transport
WT26_RS17420	COG0735	belongs to the Fur family
WT26_RS17430	COG1121	(ABC) transporter
WT26_RS17435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WT26_RS17440	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
WT26_RS17450	COG1070	Carbohydrate kinase
WT26_RS17455	COG2233	PERMEase
WT26_RS17465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WT26_RS17470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WT26_RS17485	COG4977	sequence-specific DNA binding
WT26_RS17505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WT26_RS17520	COG2027	D-alanyl-D-alanine carboxypeptidase
WT26_RS17535	COG0009	L-threonylcarbamoyladenylate synthase
WT26_RS17540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WT26_RS17545	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WT26_RS17550	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WT26_RS17560	COG0469	pyruvate kinase activity
WT26_RS17565	COG0126	phosphoglycerate kinase activity
WT26_RS17600	COG0429	hydrolase of the alpha beta-hydrolase fold
WT26_RS17610	COG4783	chaperone-mediated protein folding
WT26_RS17615	COG0315	cyclic pyranopterin monophosphate synthase activity
WT26_RS17640	COG4969	Belongs to the N-Me-Phe pilin family
WT26_RS17645	COG0861	Integral membrane protein TerC family
WT26_RS17650	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WT26_RS17665	COG2137	regulation of response to DNA damage stimulus
WT26_RS17670	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WT26_RS17695	COG0583	DNA-binding transcription factor activity
WT26_RS17700	COG4977	sequence-specific DNA binding
WT26_RS17730	COG1301	dicarboxylic acid transport
WT26_RS17750	COG4948	Mandelate Racemase Muconate Lactonizing
WT26_RS17760	COG2863	cytochrome
WT26_RS17770	COG0513	Belongs to the DEAD box helicase family
WT26_RS17810	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WT26_RS17815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WT26_RS17820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WT26_RS17830	COG1396	sequence-specific DNA binding
WT26_RS17835	COG2814	Major facilitator Superfamily
WT26_RS17850	COG1702	phosphate starvation-inducible protein PhoH
WT26_RS17860	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
WT26_RS17870	COG0815	Transfers the fatty acyl group on membrane lipoproteins
WT26_RS17880	COG0752	glycyl-tRNA synthetase alpha subunit
WT26_RS17885	COG0751	glycine-tRNA ligase activity
WT26_RS17890	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WT26_RS17895	COG0204	Acyl-transferase
WT26_RS17920	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WT26_RS17945	COG5265	(ABC) transporter
WT26_RS17960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WT26_RS17970	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WT26_RS18010	COG0534	Mate efflux family protein
WT26_RS18025	COG1024	Enoyl-CoA hydratase
WT26_RS18030	COG0183	Belongs to the thiolase family
WT26_RS18035	COG1024	Enoyl-CoA hydratase
WT26_RS18035	COG1250	3-hydroxyacyl-CoA dehydrogenase
WT26_RS18040	COG1960	acyl-CoA dehydrogenase activity
WT26_RS18055	COG0494	nUDIX hydrolase
WT26_RS18075	COG0500	methyltransferase
WT26_RS18115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WT26_RS18120	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WT26_RS18120	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WT26_RS18145	COG0251	oxidation-reduction process
WT26_RS18150	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
WT26_RS18155	COG1737	Transcriptional regulator
WT26_RS18155	COG0837	glucose binding
WT26_RS18165	COG3344	reverse transcriptase
WT26_RS18180	COG0477	Major facilitator Superfamily
WT26_RS18195	COG0235	Class ii aldolase
WT26_RS18200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WT26_RS18205	COG2186	Transcriptional regulator
WT26_RS18210	COG0247	lactate metabolic process
WT26_RS18220	COG1139	Iron-sulfur cluster binding protein
WT26_RS18225	COG1620	l-lactate permease
WT26_RS18230	COG0501	Belongs to the peptidase M48B family
WT26_RS18260	COG1028	Short-chain dehydrogenase reductase Sdr
WT26_RS18300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WT26_RS18325	COG1028	Short-chain dehydrogenase reductase Sdr
WT26_RS18330	COG0183	Belongs to the thiolase family
WT26_RS18380	COG0629	single-stranded DNA binding
WT26_RS18385	COG2814	Major facilitator Superfamily
WT26_RS18410	COG1280	lysine exporter protein (LysE YggA)
WT26_RS18430	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WT26_RS18445	COG1137	ATPase activity
WT26_RS18450	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WT26_RS18455	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WT26_RS18480	COG1194	a g-specific adenine glycosylase
WT26_RS18495	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
WT26_RS18500	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WT26_RS18510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WT26_RS18530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WT26_RS18540	COG0742	ribosomal rna small subunit methyltransferase
WT26_RS18550	COG0625	glutathione transferase activity
WT26_RS18555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WT26_RS18560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WT26_RS18570	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WT26_RS18575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WT26_RS18590	COG1294	oxidase, subunit
WT26_RS18605	COG2190	(PTS) system
WT26_RS18605	COG1263	PTS System
WT26_RS18605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WT26_RS18610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WT26_RS18610	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WT26_RS18615	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WT26_RS18620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WT26_RS18625	COG2188	Transcriptional regulator
WT26_RS18630	COG0587	DNA-directed DNA polymerase activity
WT26_RS18645	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WT26_RS18675	COG0840	transmembrane signaling receptor activity
WT26_RS18685	COG1999	signal sequence binding
WT26_RS18695	COG1612	heme a metabolic process
WT26_RS18735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WT26_RS18755	COG1040	competence protein
WT26_RS18765	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
WT26_RS18785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WT26_RS18795	COG0793	Belongs to the peptidase S41A family
WT26_RS18800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WT26_RS18805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WT26_RS18810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WT26_RS18820	COG0189	ligase activity
WT26_RS18830	COG0004	ammonium transporteR
WT26_RS18840	COG2960	long-chain fatty acid transporting porin activity
WT26_RS18845	COG0606	chelatase, subunit chli
WT26_RS18865	COG4191	Histidine kinase
WT26_RS18870	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WT26_RS18880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WT26_RS18885	COG1960	acyl-CoA dehydrogenase activity
WT26_RS18890	COG1960	acyl-CoA dehydrogenase activity
WT26_RS18900	COG0583	DNA-binding transcription factor activity
WT26_RS18905	COG0405	Gamma-glutamyltransferase
WT26_RS18910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WT26_RS18920	COG4521	taurine ABC transporter
WT26_RS18945	COG0583	DNA-binding transcription factor activity
WT26_RS18950	COG2921	Belongs to the UPF0250 family
WT26_RS18960	COG1686	Belongs to the peptidase S11 family
WT26_RS18990	COG1127	ABC transporter
WT26_RS18995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WT26_RS19000	COG0737	Belongs to the 5'-nucleotidase family
WT26_RS19025	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
WT26_RS19025	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
WT26_RS19040	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WT26_RS19060	COG1024	Enoyl-CoA hydratase
WT26_RS19110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WT26_RS19115	COG0300	oxidoreductase activity
WT26_RS19120	COG0747	negative chemotaxis
WT26_RS19145	COG0288	reversible hydration of carbon dioxide
WT26_RS19150	COG0183	Belongs to the thiolase family
WT26_RS19155	COG0300	oxidoreductase activity
WT26_RS19160	COG3012	SEC-C Motif Domain Protein
WT26_RS19185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WT26_RS19195	COG2199	diguanylate cyclase activity
WT26_RS19195	COG2200	EAL domain
WT26_RS19200	COG0025	NhaP-type Na H and K H
WT26_RS19215	COG0477	Major facilitator Superfamily
WT26_RS19220	COG0625	glutathione transferase activity
WT26_RS19245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WT26_RS19260	COG0583	DNA-binding transcription factor activity
WT26_RS19270	COG0625	glutathione transferase activity
WT26_RS19275	COG0583	DNA-binding transcription factor activity
WT26_RS19285	COG3511	phospholipase C
WT26_RS19295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WT26_RS19320	COG1522	sequence-specific DNA binding
WT26_RS19325	COG0596	Alpha beta hydrolase
WT26_RS19335	COG0583	DNA-binding transcription factor activity
WT26_RS19360	COG1609	Transcriptional regulator
WT26_RS19415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WT26_RS19455	COG1012	belongs to the aldehyde dehydrogenase family
WT26_RS19470	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WT26_RS19475	COG0174	glutamine synthetase
WT26_RS19490	COG3842	ATPase activity
WT26_RS19495	COG1176	ABC-type spermidine putrescine transport system, permease component I
WT26_RS19500	COG1177	transmembrane transport
WT26_RS19510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WT26_RS19515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WT26_RS19545	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WT26_RS19555	COG2824	Alkylphosphonate utilization operon protein PhnA
WT26_RS19570	COG0583	DNA-binding transcription factor activity
WT26_RS19575	COG2233	PERMEase
WT26_RS19580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WT26_RS19590	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
WT26_RS19600	COG1706	bacterial-type flagellum-dependent cell motility
WT26_RS19625	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
WT26_RS19630	COG1558	bacterial-type flagellum-dependent cell motility
WT26_RS19635	COG1815	bacterial-type flagellum-dependent cell motility
WT26_RS19655	COG3240	lipase activity
WT26_RS19660	COG0006	proline dipeptidase activity
WT26_RS19665	COG1396	sequence-specific DNA binding
WT26_RS19685	COG0741	lytic transglycosylase activity
WT26_RS19690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WT26_RS19700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WT26_RS19705	COG1984	allophanate hydrolase subunit 2
WT26_RS19720	COG4608	Belongs to the ABC transporter superfamily
WT26_RS19725	COG0444	Belongs to the ABC transporter superfamily
WT26_RS19730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WT26_RS19735	COG0601	transmembrane transport
WT26_RS19755	COG0579	oxidoreductase
WT26_RS19760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WT26_RS19770	COG3568	Endonuclease Exonuclease Phosphatase
WT26_RS19785	COG2197	response regulator
WT26_RS19790	COG0531	amino acid
WT26_RS19810	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WT26_RS19820	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WT26_RS19850	COG1157	protein secretion by the type III secretion system
WT26_RS19900	COG0667	Aldo Keto reductase
WT26_RS19930	COG1560	Kdo2-lipid A biosynthetic process
WT26_RS19935	COG3093	addiction module antidote protein HigA
WT26_RS19945	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WT26_RS19955	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WT26_RS19965	COG0523	cobalamin synthesis protein
WT26_RS19995	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
WT26_RS20020	COG1309	transcriptional regulator
WT26_RS20095	COG2885	chlorophyll binding
WT26_RS20095	COG3047	cAMP biosynthetic process
WT26_RS20140	COG3188	usher protein
WT26_RS20145	COG3121	Chaperone
WT26_RS20160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WT26_RS20160	COG2813	Specifically methylates the guanine in position
WT26_RS20165	COG2814	Major facilitator Superfamily
WT26_RS20175	COG2207	Transcriptional regulator
WT26_RS20180	COG1064	alcohol dehydrogenase
WT26_RS20185	COG0708	Exodeoxyribonuclease III
WT26_RS20190	COG2326	polyphosphate kinase activity
WT26_RS20195	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WT26_RS20205	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WT26_RS20210	COG1077	Cell shape determining protein MreB Mrl
WT26_RS20225	COG0768	penicillin binding
WT26_RS20230	COG0772	Belongs to the SEDS family
WT26_RS20245	COG0720	synthase
WT26_RS20250	COG0602	queuosine metabolic process
WT26_RS20265	COG2204	response regulator
WT26_RS20285	COG0501	Belongs to the peptidase M48B family
WT26_RS20300	COG0242	peptide deformylase activity
WT26_RS20305	COG0758	DNA mediated transformation
WT26_RS20320	COG0583	DNA-binding transcription factor activity
WT26_RS20325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WT26_RS20370	COG1126	abc transporter atp-binding protein
WT26_RS20375	COG0765	amino acid transport
WT26_RS20380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WT26_RS20390	COG1012	belongs to the aldehyde dehydrogenase family
WT26_RS20400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WT26_RS20420	COG3511	phospholipase C
WT26_RS20425	COG0583	DNA-binding transcription factor activity
WT26_RS20430	COG1620	l-lactate permease
WT26_RS20440	COG2918	glutathione biosynthetic process
WT26_RS20450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WT26_RS20450	COG2169	Transcriptional regulator
WT26_RS20470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WT26_RS20480	COG2203	Gaf domain
WT26_RS20480	COG4251	negative regulation of phosphorylation
WT26_RS20480	COG5001	Diguanylate cyclase
WT26_RS20480	COG3706	GGDEF domain
WT26_RS20710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WT26_RS20780	COG1346	cytolysis
WT26_RS21300	COG0210	DNA helicase
WT26_RS22750	COG0443	Heat shock 70 kDa protein
WT26_RS22945	COG0243	molybdopterin cofactor binding
WT26_RS22985	COG3116	cell division
WT26_RS23005	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WT26_RS23380	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WT26_RS23420	COG1063	alcohol dehydrogenase
WT26_RS23430	COG2814	Major facilitator Superfamily
WT26_RS23535	COG1126	abc transporter atp-binding protein
WT26_RS23910	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WT26_RS24180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WT26_RS24470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WT26_RS24570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WT26_RS24780	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WT26_RS25615	COG0546	phosphoglycolate phosphatase activity
WT26_RS25850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WT26_RS26000	COG0668	transmembrane transport
WT26_RS26055	COG1074	ATP-dependent DNA helicase activity
WT26_RS26185	COG0753	catalase activity
WT26_RS26340	COG1388	LysM domain
WT26_RS26340	COG0741	lytic transglycosylase activity
WT26_RS26365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WT26_RS26385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WT26_RS26755	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
WT26_RS26980	COG1172	Belongs to the binding-protein-dependent transport system permease family
WT26_RS27030	COG0525	valine-tRNA ligase activity
WT26_RS27285	COG0195	Participates in both transcription termination and antitermination
WT26_RS27300	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WT26_RS27335	COG1217	gtp-binding protein TYPA
WT26_RS27525	COG4771	TonB-dependent receptor
WT26_RS27825	COG2766	serine protein kinase
WT26_RS27990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WT26_RS27990	COG1028	Short-chain dehydrogenase reductase Sdr
WT26_RS27990	COG3321	synthase
WT26_RS27990	COG4221	oxidoreductase activity
WT26_RS28045	COG3486	L-lysine 6-monooxygenase (NADPH) activity
WT26_RS28520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WT26_RS28640	COG0038	chloride channel
WT26_RS28975	COG3243	poly(R)-hydroxyalkanoic acid synthase
WT26_RS29065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WT26_RS29160	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WT26_RS29220	COG0542	response to heat
WT26_RS29460	COG1024	Enoyl-CoA hydratase
WT26_RS29460	COG1250	3-hydroxyacyl-CoA dehydrogenase
WT26_RS30250	COG4239	(ABC) transporter, permease
WT26_RS30640	COG3842	ATPase activity
WT26_RS30880	COG2850	peptidyl-arginine hydroxylation
WT26_RS30925	COG2333	competence protein COMEC
WT26_RS30925	COG0658	competence protein
WT26_RS31445	COG1459	type II secretion system
WT26_RS32305	COG3135	benzoate transporter
WT26_RS32680	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WT26_RS32705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WT26_RS32825	COG1492	cobalamin metabolic process
WT26_RS33080	COG0542	response to heat
WT26_RS33175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WT26_RS33340	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WT26_RS33475	COG3842	ATPase activity
WT26_RS33825	COG4948	Mandelate Racemase Muconate Lactonizing
WT26_RS34550	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WT26_RS34600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WT26_RS34615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WT26_RS34680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)