locus-tag	class	description
BRPE64_RS00070	COG0513	Belongs to the DEAD box helicase family
BRPE64_RS00075	COG2814	Major facilitator Superfamily
BRPE64_RS00105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BRPE64_RS00110	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BRPE64_RS00115	COG0583	DNA-binding transcription factor activity
BRPE64_RS00130	COG0758	DNA mediated transformation
BRPE64_RS00135	COG0242	peptide deformylase activity
BRPE64_RS00140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BRPE64_RS00150	COG0501	Belongs to the peptidase M48B family
BRPE64_RS00155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BRPE64_RS00155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BRPE64_RS00165	COG5000	phosphorelay sensor kinase activity
BRPE64_RS00170	COG2204	response regulator
BRPE64_RS00185	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BRPE64_RS00190	COG0602	queuosine metabolic process
BRPE64_RS00210	COG0772	Belongs to the SEDS family
BRPE64_RS00215	COG0768	penicillin binding
BRPE64_RS00225	COG1792	Involved in formation and maintenance of cell shape
BRPE64_RS00230	COG1077	Cell shape determining protein MreB Mrl
BRPE64_RS00235	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BRPE64_RS00240	COG0154	amidase activity
BRPE64_RS00245	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BRPE64_RS00250	COG2326	polyphosphate kinase activity
BRPE64_RS00255	COG0708	Exodeoxyribonuclease III
BRPE64_RS00265	COG2814	Major facilitator Superfamily
BRPE64_RS00285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BRPE64_RS00300	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BRPE64_RS00305	COG0840	transmembrane signaling receptor activity
BRPE64_RS00310	COG2233	PERMEase
BRPE64_RS00320	COG0025	NhaP-type Na H and K H
BRPE64_RS00325	COG2200	EAL domain
BRPE64_RS00325	COG2199	diguanylate cyclase activity
BRPE64_RS00335	COG0625	glutathione transferase activity
BRPE64_RS00400	COG0596	Alpha beta hydrolase
BRPE64_RS00405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRPE64_RS00425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BRPE64_RS00430	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BRPE64_RS00435	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BRPE64_RS00440	COG0156	8-amino-7-oxononanoate synthase activity
BRPE64_RS00455	COG3012	SEC-C Motif Domain Protein
BRPE64_RS00460	COG0625	glutathione transferase activity
BRPE64_RS00465	COG0300	oxidoreductase activity
BRPE64_RS00480	COG0183	Belongs to the thiolase family
BRPE64_RS00485	COG0288	reversible hydration of carbon dioxide
BRPE64_RS00490	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BRPE64_RS00495	COG0789	Transcriptional regulator
BRPE64_RS00505	COG0747	negative chemotaxis
BRPE64_RS00535	COG0667	Aldo Keto reductase
BRPE64_RS00540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BRPE64_RS00555	COG2818	Glycosylase
BRPE64_RS00565	COG0561	phosphatase activity
BRPE64_RS00575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BRPE64_RS00580	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS00605	COG1360	Flagellar Motor Protein
BRPE64_RS00615	COG2198	Histidine kinase
BRPE64_RS00615	COG0643	Histidine kinase
BRPE64_RS00620	COG0835	chemotaxis
BRPE64_RS00625	COG0840	transmembrane signaling receptor activity
BRPE64_RS00635	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BRPE64_RS00640	COG2201	protein-glutamate methylesterase activity
BRPE64_RS00645	COG0745	RESPONSE REGULATOR receiver
BRPE64_RS00650	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BRPE64_RS00665	COG0300	oxidoreductase activity
BRPE64_RS00670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BRPE64_RS00680	COG0018	arginyl-trna synthetase
BRPE64_RS00695	COG1410	methionine synthase
BRPE64_RS00695	COG0646	methionine synthase
BRPE64_RS00710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BRPE64_RS00735	COG1024	Enoyl-CoA hydratase
BRPE64_RS00755	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BRPE64_RS00765	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BRPE64_RS00780	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
BRPE64_RS00785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BRPE64_RS00790	COG1127	ABC transporter
BRPE64_RS00820	COG1686	Belongs to the peptidase S11 family
BRPE64_RS00835	COG0583	DNA-binding transcription factor activity
BRPE64_RS00845	COG0321	lipoyl(octanoyl) transferase activity
BRPE64_RS00855	COG1301	dicarboxylic acid transport
BRPE64_RS00860	COG4191	Histidine kinase
BRPE64_RS00865	COG2204	response regulator
BRPE64_RS00880	COG0606	chelatase, subunit chli
BRPE64_RS00885	COG2960	long-chain fatty acid transporting porin activity
BRPE64_RS00895	COG0004	ammonium transporteR
BRPE64_RS00905	COG0189	ligase activity
BRPE64_RS00915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRPE64_RS00920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BRPE64_RS00925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BRPE64_RS00930	COG0793	Belongs to the peptidase S41A family
BRPE64_RS00935	COG0588	phosphoglycerate mutase activity
BRPE64_RS00940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BRPE64_RS00945	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BRPE64_RS00950	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BRPE64_RS00955	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BRPE64_RS00960	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BRPE64_RS00965	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BRPE64_RS00970	COG1040	competence protein
BRPE64_RS00975	COG2226	methyltransferase
BRPE64_RS00985	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BRPE64_RS00990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BRPE64_RS01000	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BRPE64_RS01030	COG1612	heme a metabolic process
BRPE64_RS01035	COG0109	protoheme IX farnesyltransferase activity
BRPE64_RS01040	COG1999	signal sequence binding
BRPE64_RS01055	COG0456	acetyltransferase
BRPE64_RS01055	COG1846	Transcriptional regulator
BRPE64_RS01060	COG2188	Transcriptional regulator
BRPE64_RS01065	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BRPE64_RS01070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BRPE64_RS01075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BRPE64_RS01075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRPE64_RS01080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRPE64_RS01080	COG2190	(PTS) system
BRPE64_RS01080	COG1263	PTS System
BRPE64_RS01085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BRPE64_RS01100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BRPE64_RS01105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BRPE64_RS01115	COG0625	glutathione transferase activity
BRPE64_RS01130	COG0742	ribosomal rna small subunit methyltransferase
BRPE64_RS01135	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BRPE64_RS01140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BRPE64_RS01145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BRPE64_RS01160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BRPE64_RS01180	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BRPE64_RS01190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BRPE64_RS01195	COG1194	a g-specific adenine glycosylase
BRPE64_RS01205	COG1660	Displays ATPase and GTPase activities
BRPE64_RS01210	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BRPE64_RS01220	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BRPE64_RS01225	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BRPE64_RS01230	COG1137	ATPase activity
BRPE64_RS01245	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BRPE64_RS01260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BRPE64_RS01265	COG1280	lysine exporter protein (LysE YggA)
BRPE64_RS01290	COG2814	Major facilitator Superfamily
BRPE64_RS01295	COG0629	single-stranded DNA binding
BRPE64_RS01300	COG2197	response regulator
BRPE64_RS01305	COG2197	response regulator
BRPE64_RS01310	COG2197	response regulator
BRPE64_RS01320	COG0583	DNA-binding transcription factor activity
BRPE64_RS01345	COG0477	Major facilitator Superfamily
BRPE64_RS01360	COG1737	Transcriptional regulator
BRPE64_RS01365	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BRPE64_RS01380	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BRPE64_RS01380	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BRPE64_RS01390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BRPE64_RS01410	COG2226	methyltransferase
BRPE64_RS01425	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BRPE64_RS01445	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BRPE64_RS01450	COG0494	nUDIX hydrolase
BRPE64_RS01465	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS01470	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRPE64_RS01470	COG1024	Enoyl-CoA hydratase
BRPE64_RS01475	COG0183	Belongs to the thiolase family
BRPE64_RS01480	COG1024	Enoyl-CoA hydratase
BRPE64_RS01485	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BRPE64_RS01505	COG5265	(ABC) transporter
BRPE64_RS01515	COG2223	nitrite transmembrane transporter activity
BRPE64_RS01520	COG0583	DNA-binding transcription factor activity
BRPE64_RS01525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BRPE64_RS01535	COG0765	amino acid transport
BRPE64_RS01540	COG0765	amino acid transport
BRPE64_RS01545	COG1126	abc transporter atp-binding protein
BRPE64_RS01550	COG0121	glutamine amidotransferase
BRPE64_RS01555	COG0418	dihydroorotase activity
BRPE64_RS01570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BRPE64_RS01575	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BRPE64_RS01580	COG0316	Belongs to the HesB IscA family
BRPE64_RS01585	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BRPE64_RS01595	COG1490	D-aminoacyl-tRNA deacylase activity
BRPE64_RS01640	COG2255	four-way junction helicase activity
BRPE64_RS01645	COG0632	four-way junction helicase activity
BRPE64_RS01650	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BRPE64_RS01655	COG0138	bifunctional purine biosynthesis protein purh
BRPE64_RS01660	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BRPE64_RS01665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BRPE64_RS01670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BRPE64_RS01675	COG0006	proline dipeptidase activity
BRPE64_RS01705	COG0482	sulfurtransferase activity
BRPE64_RS01720	COG0625	glutathione transferase activity
BRPE64_RS01725	COG3009	Protein conserved in bacteria
BRPE64_RS01730	COG3008	intermembrane lipid transfer
BRPE64_RS01735	COG2995	paraquat-inducible protein a
BRPE64_RS01745	COG3038	cytochrome b561
BRPE64_RS01755	COG2353	YceI-like domain
BRPE64_RS01760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BRPE64_RS01765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BRPE64_RS01770	COG1862	Preprotein translocase
BRPE64_RS01775	COG0343	queuine tRNA-ribosyltransferase activity
BRPE64_RS01780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BRPE64_RS01785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BRPE64_RS01795	COG0753	catalase activity
BRPE64_RS01800	COG0783	Belongs to the Dps family
BRPE64_RS01805	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BRPE64_RS01825	COG0247	lactate metabolic process
BRPE64_RS01830	COG0277	FAD linked oxidase domain protein
BRPE64_RS01835	COG0277	FAD linked oxidase domain protein
BRPE64_RS01840	COG0277	FAD linked oxidase domain protein
BRPE64_RS01845	COG2096	Adenosyltransferase
BRPE64_RS01855	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BRPE64_RS01860	COG0312	modulator of DNA gyrase
BRPE64_RS01865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BRPE64_RS01875	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BRPE64_RS01880	COG0497	DNA recombination
BRPE64_RS01890	COG1420	regulation of RNA biosynthetic process
BRPE64_RS01895	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BRPE64_RS01905	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BRPE64_RS01915	COG0443	Heat shock 70 kDa protein
BRPE64_RS01925	COG0512	Glutamine amidotransferase of anthranilate synthase
BRPE64_RS01925	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BRPE64_RS01930	COG4948	Mandelate Racemase Muconate Lactonizing
BRPE64_RS01935	COG2186	Transcriptional regulator
BRPE64_RS01950	COG0697	spore germination
BRPE64_RS01955	COG0346	lactoylglutathione lyase activity
BRPE64_RS01965	COG0204	Acyl-transferase
BRPE64_RS01970	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BRPE64_RS01975	COG0751	glycine-tRNA ligase activity
BRPE64_RS01980	COG0752	glycyl-tRNA synthetase alpha subunit
BRPE64_RS01985	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BRPE64_RS01990	COG4535	Mg2 and Co2 transporter CorC
BRPE64_RS01995	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BRPE64_RS02000	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BRPE64_RS02005	COG1702	phosphate starvation-inducible protein PhoH
BRPE64_RS02010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BRPE64_RS02015	COG0583	DNA-binding transcription factor activity
BRPE64_RS02025	COG2814	Major facilitator Superfamily
BRPE64_RS02030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BRPE64_RS02040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BRPE64_RS02075	COG0513	Belongs to the DEAD box helicase family
BRPE64_RS02080	COG1272	protein, Hemolysin III
BRPE64_RS02085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BRPE64_RS02085	COG2010	Cytochrome c
BRPE64_RS02105	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BRPE64_RS02110	COG1428	Deoxynucleoside kinase
BRPE64_RS02115	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BRPE64_RS02130	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BRPE64_RS02135	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BRPE64_RS02140	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BRPE64_RS02145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BRPE64_RS02150	COG0586	Pfam SNARE associated Golgi protein
BRPE64_RS02195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BRPE64_RS02225	COG0642	Histidine kinase
BRPE64_RS02235	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BRPE64_RS02240	COG2137	regulation of response to DNA damage stimulus
BRPE64_RS02250	COG0045	succinate-CoA ligase (ADP-forming) activity
BRPE64_RS02255	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BRPE64_RS02260	COG0861	Integral membrane protein TerC family
BRPE64_RS02265	COG4969	Belongs to the N-Me-Phe pilin family
BRPE64_RS02275	COG0315	cyclic pyranopterin monophosphate synthase activity
BRPE64_RS02290	COG0429	hydrolase of the alpha beta-hydrolase fold
BRPE64_RS02300	COG0859	PFAM glycosyl transferase family 9
BRPE64_RS02325	COG0126	phosphoglycerate kinase activity
BRPE64_RS02330	COG0469	pyruvate kinase activity
BRPE64_RS02340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BRPE64_RS02345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BRPE64_RS02350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BRPE64_RS02355	COG0009	L-threonylcarbamoyladenylate synthase
BRPE64_RS02365	COG2027	D-alanyl-D-alanine carboxypeptidase
BRPE64_RS02375	COG0642	Histidine kinase
BRPE64_RS02405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BRPE64_RS02425	COG1335	isochorismatase
BRPE64_RS02435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRPE64_RS02440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRPE64_RS02450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRPE64_RS02455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRPE64_RS02465	COG2233	PERMEase
BRPE64_RS02470	COG1070	Carbohydrate kinase
BRPE64_RS02495	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BRPE64_RS02505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BRPE64_RS02510	COG1121	(ABC) transporter
BRPE64_RS02520	COG0735	belongs to the Fur family
BRPE64_RS02540	COG1175	transmembrane transport
BRPE64_RS02555	COG3842	ATPase activity
BRPE64_RS02560	COG0633	Ferredoxin
BRPE64_RS02560	COG3217	Mosc domain protein beta barrel domain protein
BRPE64_RS02570	COG1070	Carbohydrate kinase
BRPE64_RS02575	COG0246	Mannitol dehydrogenase
BRPE64_RS02590	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BRPE64_RS02615	COG2814	Major facilitator Superfamily
BRPE64_RS02630	COG1201	RNA secondary structure unwinding
BRPE64_RS02635	COG1793	dna ligase
BRPE64_RS02635	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BRPE64_RS02640	COG1793	dna ligase
BRPE64_RS02640	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BRPE64_RS02650	COG0583	DNA-binding transcription factor activity
BRPE64_RS02655	COG2985	domain, Protein
BRPE64_RS02660	COG2985	domain, Protein
BRPE64_RS02665	COG0656	L-ascorbic acid biosynthetic process
BRPE64_RS02680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRPE64_RS02685	COG0601	transmembrane transport
BRPE64_RS02690	COG4166	transmembrane transport
BRPE64_RS02720	COG1278	Cold shock
BRPE64_RS02725	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BRPE64_RS02730	COG0542	response to heat
BRPE64_RS02740	COG0756	dUTP diphosphatase activity
BRPE64_RS02745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BRPE64_RS02755	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BRPE64_RS02760	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BRPE64_RS02765	COG0196	riboflavin kinase activity
BRPE64_RS02770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BRPE64_RS02775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BRPE64_RS02775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BRPE64_RS02780	COG3264	Mechanosensitive ion channel
BRPE64_RS02780	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BRPE64_RS02790	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BRPE64_RS02800	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BRPE64_RS02805	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BRPE64_RS02820	COG1047	Peptidyl-prolyl cis-trans
BRPE64_RS02825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BRPE64_RS02860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BRPE64_RS02865	COG0543	2 iron, 2 sulfur cluster binding
BRPE64_RS02865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BRPE64_RS02960	COG0582	viral genome integration into host DNA
BRPE64_RS02975	COG0583	DNA-binding transcription factor activity
BRPE64_RS02980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BRPE64_RS02990	COG0175	sulfate reduction
BRPE64_RS03000	COG2895	sulfate adenylyltransferase (ATP) activity
BRPE64_RS03005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BRPE64_RS03005	COG1648	precorrin-2 dehydrogenase activity
BRPE64_RS03025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BRPE64_RS03040	COG4654	Cytochrome c, class I
BRPE64_RS03050	COG0583	DNA-binding transcription factor activity
BRPE64_RS03055	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BRPE64_RS03080	COG4206	TonB-dependent receptor
BRPE64_RS03085	COG4139	cobalamin transport
BRPE64_RS03090	COG1120	ATPase activity
BRPE64_RS03095	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BRPE64_RS03100	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BRPE64_RS03110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BRPE64_RS03130	COG1492	cobalamin metabolic process
BRPE64_RS03150	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BRPE64_RS03155	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BRPE64_RS03190	COG3121	Chaperone
BRPE64_RS03205	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BRPE64_RS03205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BRPE64_RS03210	COG2885	chlorophyll binding
BRPE64_RS03215	COG0489	protein tyrosine kinase activity
BRPE64_RS03225	COG0717	Belongs to the dCTP deaminase family
BRPE64_RS03235	COG0625	glutathione transferase activity
BRPE64_RS03240	COG3781	membrane
BRPE64_RS03245	COG0165	Argininosuccinate lyase
BRPE64_RS03255	COG2226	methyltransferase
BRPE64_RS03260	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BRPE64_RS03270	COG0181	hydroxymethylbilane synthase activity
BRPE64_RS03290	COG1054	Belongs to the UPF0176 family
BRPE64_RS03295	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BRPE64_RS03300	COG2860	membrane
BRPE64_RS03305	COG2840	Smr protein MutS2
BRPE64_RS03310	COG0492	ferredoxin-NADP+ reductase activity
BRPE64_RS03315	COG1674	ftsk spoiiie
BRPE64_RS03320	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BRPE64_RS03330	COG0583	DNA-binding transcription factor activity
BRPE64_RS03345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BRPE64_RS03370	COG0024	Methionine aminopeptidase
BRPE64_RS03380	COG0850	regulation of cytokinetic process
BRPE64_RS03390	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BRPE64_RS03415	COG0477	Major facilitator Superfamily
BRPE64_RS03510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BRPE64_RS03535	COG0038	chloride channel
BRPE64_RS03575	COG4584	PFAM Integrase catalytic
BRPE64_RS03580	COG1484	DNA-dependent DNA replication
BRPE64_RS03650	COG0582	viral genome integration into host DNA
BRPE64_RS03660	COG2814	Major facilitator Superfamily
BRPE64_RS03665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BRPE64_RS03670	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BRPE64_RS03675	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BRPE64_RS03680	COG1561	YicC-like family, N-terminal region
BRPE64_RS03685	COG0194	GDP metabolic process
BRPE64_RS03695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BRPE64_RS03720	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BRPE64_RS03730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BRPE64_RS03730	COG1199	ATP-dependent helicase activity
BRPE64_RS03750	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BRPE64_RS03755	COG0308	aminopeptidase N
BRPE64_RS03790	COG0028	Belongs to the TPP enzyme family
BRPE64_RS03790	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BRPE64_RS03795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BRPE64_RS03805	COG0402	S-adenosylhomocysteine deaminase activity
BRPE64_RS03810	COG2252	PERMEase
BRPE64_RS03815	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BRPE64_RS03825	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BRPE64_RS03835	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BRPE64_RS03865	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BRPE64_RS03875	COG0762	integral membrane protein
BRPE64_RS03900	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BRPE64_RS03910	COG0436	Aminotransferase
BRPE64_RS03915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BRPE64_RS03920	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BRPE64_RS03935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BRPE64_RS03935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BRPE64_RS03940	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BRPE64_RS03950	COG2814	Major facilitator Superfamily
BRPE64_RS03955	COG1505	serine-type exopeptidase activity
BRPE64_RS03960	COG3842	ATPase activity
BRPE64_RS03965	COG0395	ABC-type sugar transport system, permease component
BRPE64_RS03970	COG1175	transmembrane transport
BRPE64_RS03980	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BRPE64_RS03990	COG0837	glucose binding
BRPE64_RS03990	COG1737	Transcriptional regulator
BRPE64_RS04025	COG1741	Belongs to the pirin family
BRPE64_RS04060	COG1116	anion transmembrane transporter activity
BRPE64_RS04075	COG2204	response regulator
BRPE64_RS04095	COG2204	response regulator
BRPE64_RS04110	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BRPE64_RS04120	COG1295	ribonuclease BN
BRPE64_RS04125	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BRPE64_RS04130	COG2823	Periplasmic or secreted lipoprotein
BRPE64_RS04165	COG0693	protein deglycase activity
BRPE64_RS04170	COG2814	Major facilitator Superfamily
BRPE64_RS04175	COG1881	PFAM PEBP family protein
BRPE64_RS04195	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BRPE64_RS04220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BRPE64_RS04225	COG1773	rubredoxin
BRPE64_RS04235	COG0488	(ABC) transporter
BRPE64_RS04265	COG0384	phenazine biosynthesis protein PhzF
BRPE64_RS04275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRPE64_RS04280	COG0697	spore germination
BRPE64_RS04290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRPE64_RS04325	COG3161	chorismate lyase activity
BRPE64_RS04350	COG1289	transmembrane transporter activity
BRPE64_RS04355	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BRPE64_RS04360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BRPE64_RS04365	COG3135	benzoate transporter
BRPE64_RS04380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BRPE64_RS04400	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BRPE64_RS04405	COG2878	Part of a membrane complex involved in electron transport
BRPE64_RS04410	COG1309	transcriptional regulator
BRPE64_RS04420	COG3387	PFAM Glycoside hydrolase 15-related
BRPE64_RS04435	COG2706	6-phosphogluconolactonase activity
BRPE64_RS04445	COG1674	ftsk spoiiie
BRPE64_RS04445	COG1674	ftsk spoiiie
BRPE64_RS04455	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BRPE64_RS04465	COG0513	Belongs to the DEAD box helicase family
BRPE64_RS04470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BRPE64_RS04475	COG1054	Belongs to the UPF0176 family
BRPE64_RS04495	COG1215	transferase activity, transferring glycosyl groups
BRPE64_RS04515	COG1530	ribonuclease E activity
BRPE64_RS04525	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BRPE64_RS04530	COG0799	negative regulation of ribosome biogenesis
BRPE64_RS04540	COG0408	coproporphyrinogen oxidase activity
BRPE64_RS04545	COG0151	Belongs to the GarS family
BRPE64_RS04550	COG0217	transcriptional regulatory protein
BRPE64_RS04555	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BRPE64_RS04560	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS04575	COG0745	RESPONSE REGULATOR receiver
BRPE64_RS04615	COG0668	transmembrane transport
BRPE64_RS04625	COG1522	sequence-specific DNA binding
BRPE64_RS04635	COG1289	transmembrane transporter activity
BRPE64_RS04640	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BRPE64_RS04645	COG1074	ATP-dependent DNA helicase activity
BRPE64_RS04650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BRPE64_RS04670	COG1620	l-lactate permease
BRPE64_RS04685	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BRPE64_RS04690	COG0697	spore germination
BRPE64_RS04705	COG4585	Histidine kinase
BRPE64_RS04720	COG0783	Belongs to the Dps family
BRPE64_RS04725	COG2197	response regulator
BRPE64_RS04735	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BRPE64_RS04755	COG3850	Histidine kinase
BRPE64_RS04755	COG5002	protein histidine kinase activity
BRPE64_RS04780	COG0477	Major facilitator Superfamily
BRPE64_RS04785	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BRPE64_RS04790	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BRPE64_RS04790	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BRPE64_RS04800	COG1643	Atp-dependent helicase
BRPE64_RS04820	COG1058	Belongs to the CinA family
BRPE64_RS04820	COG1546	Belongs to the CinA family
BRPE64_RS04835	COG0174	glutamine synthetase
BRPE64_RS04840	COG3852	Histidine kinase
BRPE64_RS04845	COG2204	response regulator
BRPE64_RS04870	COG0583	DNA-binding transcription factor activity
BRPE64_RS04880	COG0402	S-adenosylhomocysteine deaminase activity
BRPE64_RS04885	COG0339	signal peptide processing
BRPE64_RS04900	COG3064	Membrane
BRPE64_RS04905	COG4566	intracellular signal transduction
BRPE64_RS04915	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BRPE64_RS04920	COG0508	dehydrogenase complex catalyzes the overall conversion of
BRPE64_RS04925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BRPE64_RS04935	COG1686	Belongs to the peptidase S11 family
BRPE64_RS04940	COG1414	Transcriptional regulator
BRPE64_RS04950	COG1139	Iron-sulfur cluster binding protein
BRPE64_RS04970	COG0556	nucleotide-excision repair
BRPE64_RS04980	COG4633	Protein conserved in bacteria
BRPE64_RS04985	COG0672	)-iron permease
BRPE64_RS04995	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BRPE64_RS05045	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BRPE64_RS05070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BRPE64_RS05080	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BRPE64_RS05100	COG0306	phosphate transporter
BRPE64_RS05150	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS05160	COG1280	lysine exporter protein (LysE YggA)
BRPE64_RS05180	COG1739	Uncharacterized protein family UPF0029
BRPE64_RS05190	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BRPE64_RS05205	COG4160	amino acid transport
BRPE64_RS05210	COG4598	ABC transporter
BRPE64_RS05240	COG3724	N-succinylarginine dihydrolase activity
BRPE64_RS05250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS05285	COG2135	peptidase activity
BRPE64_RS05295	COG0277	FAD linked oxidase domain protein
BRPE64_RS05310	COG1295	ribonuclease BN
BRPE64_RS05340	COG0477	Major facilitator Superfamily
BRPE64_RS05345	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BRPE64_RS05350	COG0644	oxidoreductase
BRPE64_RS05350	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BRPE64_RS05355	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS05365	COG4566	intracellular signal transduction
BRPE64_RS05390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BRPE64_RS05400	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BRPE64_RS05405	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BRPE64_RS05410	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BRPE64_RS05430	COG0776	regulation of translation
BRPE64_RS05470	COG2259	Doxx family
BRPE64_RS05480	COG1414	Transcriptional regulator
BRPE64_RS05490	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BRPE64_RS05505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BRPE64_RS05510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BRPE64_RS05530	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BRPE64_RS05545	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BRPE64_RS05555	COG0583	DNA-binding transcription factor activity
BRPE64_RS05565	COG2224	Isocitrate lyase
BRPE64_RS05570	COG0513	Belongs to the DEAD box helicase family
BRPE64_RS05590	COG1573	uracil-dna glycosylase
BRPE64_RS05600	COG0351	phosphomethylpyrimidine kinase
BRPE64_RS05605	COG0352	thiamine-phosphate diphosphorylase activity
BRPE64_RS05610	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BRPE64_RS05615	COG0477	Major facilitator Superfamily
BRPE64_RS05620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BRPE64_RS05635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BRPE64_RS05640	COG0488	(ABC) transporter
BRPE64_RS05645	COG0386	Belongs to the glutathione peroxidase family
BRPE64_RS05655	COG2890	protein-(glutamine-N5) methyltransferase activity
BRPE64_RS05660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BRPE64_RS05665	COG1393	Belongs to the ArsC family
BRPE64_RS05670	COG2171	N-acyltransferase activity
BRPE64_RS05695	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BRPE64_RS05700	COG0242	peptide deformylase activity
BRPE64_RS05720	COG0024	Methionine aminopeptidase
BRPE64_RS05725	COG0052	Belongs to the universal ribosomal protein uS2 family
BRPE64_RS05730	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BRPE64_RS05735	COG0528	UMP kinase activity
BRPE64_RS05745	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BRPE64_RS05755	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BRPE64_RS05760	COG0750	zinc metalloprotease
BRPE64_RS05775	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BRPE64_RS05790	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BRPE64_RS05795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BRPE64_RS05800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BRPE64_RS05805	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BRPE64_RS05820	COG0330	HflC and HflK could
BRPE64_RS05835	COG2914	Belongs to the UPF0125 (RnfH) family
BRPE64_RS05840	COG0697	spore germination
BRPE64_RS05855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BRPE64_RS05855	COG0519	Catalyzes the synthesis of GMP from XMP
BRPE64_RS05870	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BRPE64_RS05880	COG0601	transmembrane transport
BRPE64_RS05885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRPE64_RS05890	COG0444	Belongs to the ABC transporter superfamily
BRPE64_RS05895	COG4608	Belongs to the ABC transporter superfamily
BRPE64_RS05905	COG0590	tRNA wobble adenosine to inosine editing
BRPE64_RS05910	COG1619	proteins homologs of microcin C7 resistance protein MccF
BRPE64_RS05920	COG1953	Uracil, thiamine, allantoin
BRPE64_RS05935	COG3195	allantoin biosynthetic process
BRPE64_RS05935	COG3648	Uricase
BRPE64_RS05940	COG4266	Belongs to the allantoicase family
BRPE64_RS05950	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BRPE64_RS05960	COG2351	hydroxyisourate hydrolase activity
BRPE64_RS05975	COG3845	ABC transporter
BRPE64_RS05980	COG4603	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS05985	COG1079	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS05995	COG3360	Dodecin
BRPE64_RS06005	COG1970	mechanosensitive ion channel activity
BRPE64_RS06045	COG2372	response to copper ion
BRPE64_RS06100	COG1024	Enoyl-CoA hydratase
BRPE64_RS06140	COG2345	Transcriptional regulator
BRPE64_RS06145	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS06185	COG2814	Major facilitator Superfamily
BRPE64_RS06190	COG0667	Aldo Keto reductase
BRPE64_RS06200	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BRPE64_RS06230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BRPE64_RS06235	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BRPE64_RS06240	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BRPE64_RS06245	COG4208	sulfate ABC transporter
BRPE64_RS06250	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BRPE64_RS06255	COG0583	DNA-binding transcription factor activity
BRPE64_RS06260	COG0252	asparaginase activity
BRPE64_RS06265	COG1652	LysM domain
BRPE64_RS06270	COG2084	Dehydrogenase
BRPE64_RS06275	COG3622	Belongs to the hyi family
BRPE64_RS06280	COG3960	tartronate-semialdehyde synthase activity
BRPE64_RS06285	COG0583	DNA-binding transcription factor activity
BRPE64_RS06290	COG0360	Binds together with S18 to 16S ribosomal RNA
BRPE64_RS06305	COG0359	binds to the 23S rRNA
BRPE64_RS06320	COG0306	phosphate transporter
BRPE64_RS06325	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS06330	COG0791	NLP P60 protein
BRPE64_RS06335	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BRPE64_RS06340	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BRPE64_RS06355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRPE64_RS06355	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BRPE64_RS06360	COG0463	Glycosyl transferase, family 2
BRPE64_RS06365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BRPE64_RS06370	COG2076	Multidrug Resistance protein
BRPE64_RS06375	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BRPE64_RS06380	COG3737	Protein of unknown function (DUF498/DUF598)
BRPE64_RS06385	COG0436	Aminotransferase
BRPE64_RS06400	COG0488	(ABC) transporter
BRPE64_RS06420	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BRPE64_RS06425	COG3842	ATPase activity
BRPE64_RS06430	COG1176	ABC-type spermidine putrescine transport system, permease component I
BRPE64_RS06435	COG1177	transmembrane transport
BRPE64_RS06450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BRPE64_RS06455	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BRPE64_RS06465	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BRPE64_RS06470	COG0450	alkyl hydroperoxide reductase
BRPE64_RS06520	COG1929	Belongs to the glycerate kinase type-1 family
BRPE64_RS06525	COG0544	peptidyl-prolyl cis-trans isomerase activity
BRPE64_RS06530	COG0740	serine-type endopeptidase activity
BRPE64_RS06535	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BRPE64_RS06540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BRPE64_RS06545	COG0776	regulation of translation
BRPE64_RS06575	COG4181	ATPase activity
BRPE64_RS06580	COG0166	Belongs to the GPI family
BRPE64_RS06585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BRPE64_RS06585	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BRPE64_RS06590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRPE64_RS06595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BRPE64_RS06595	COG0047	phosphoribosylformylglycinamidine synthase activity
BRPE64_RS06605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BRPE64_RS06615	COG2917	probably involved in intracellular septation
BRPE64_RS06620	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BRPE64_RS06625	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BRPE64_RS06635	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRPE64_RS06635	COG1024	Enoyl-CoA hydratase
BRPE64_RS06640	COG1335	isochorismatase
BRPE64_RS06645	COG0183	Belongs to the thiolase family
BRPE64_RS06660	COG2130	NADP-dependent
BRPE64_RS06680	COG0354	folic acid binding
BRPE64_RS06685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BRPE64_RS06690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BRPE64_RS06700	COG1247	-acetyltransferase
BRPE64_RS06705	COG0084	hydrolase, TatD family'
BRPE64_RS06730	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS06755	COG1879	ABC-type sugar transport system periplasmic component
BRPE64_RS06760	COG1129	ABC transporter
BRPE64_RS06765	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS06770	COG1609	Transcriptional regulator
BRPE64_RS06775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRPE64_RS06780	COG0840	transmembrane signaling receptor activity
BRPE64_RS06790	COG2766	serine protein kinase
BRPE64_RS06795	COG2718	Belongs to the UPF0229 family
BRPE64_RS06800	COG2719	SpoVR family
BRPE64_RS06815	COG0667	Aldo Keto reductase
BRPE64_RS06820	COG0477	Major facilitator Superfamily
BRPE64_RS06825	COG0583	DNA-binding transcription factor activity
BRPE64_RS06830	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BRPE64_RS06850	COG3795	YCII-related domain
BRPE64_RS06860	COG4941	Belongs to the sigma-70 factor family
BRPE64_RS06865	COG4797	methyltransferase
BRPE64_RS06865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BRPE64_RS06870	COG0489	protein tyrosine kinase activity
BRPE64_RS06870	COG3206	protein involved in exopolysaccharide biosynthesis
BRPE64_RS06890	COG0517	IMP dehydrogenase activity
BRPE64_RS06890	COG0516	GMP reductase activity
BRPE64_RS06950	COG0583	DNA-binding transcription factor activity
BRPE64_RS06970	COG2066	Belongs to the glutaminase family
BRPE64_RS06970	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BRPE64_RS06985	COG1275	C4-dicarboxylate transporter malic acid transport protein
BRPE64_RS06995	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BRPE64_RS07010	COG1953	Uracil, thiamine, allantoin
BRPE64_RS07015	COG1295	ribonuclease BN
BRPE64_RS07035	COG2974	May be involved in recombination
BRPE64_RS07045	COG1522	sequence-specific DNA binding
BRPE64_RS07080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRPE64_RS07090	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRPE64_RS07095	COG0183	Belongs to the thiolase family
BRPE64_RS07100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BRPE64_RS07105	COG2151	metal-sulfur cluster biosynthetic enzyme
BRPE64_RS07110	COG3396	Phenylacetate-CoA oxygenase
BRPE64_RS07115	COG3460	Phenylacetate-CoA oxygenase
BRPE64_RS07120	COG3396	Phenylacetate-CoA oxygenase
BRPE64_RS07175	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS07180	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BRPE64_RS07200	COG0697	spore germination
BRPE64_RS07225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BRPE64_RS07250	COG0583	DNA-binding transcription factor activity
BRPE64_RS07270	COG4377	Putative membrane peptidase family (DUF2324)
BRPE64_RS07275	COG1609	Transcriptional regulator
BRPE64_RS07290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRPE64_RS07305	COG2855	membrane
BRPE64_RS07310	COG0243	molybdopterin cofactor binding
BRPE64_RS07315	COG0437	4 iron, 4 sulfur cluster binding
BRPE64_RS07320	COG3302	dmso reductase anchor subunit
BRPE64_RS07325	COG0626	cystathionine gamma-synthase activity
BRPE64_RS07335	COG0656	L-ascorbic acid biosynthetic process
BRPE64_RS07345	COG0038	chloride channel
BRPE64_RS07365	COG4774	siderophore transport
BRPE64_RS07370	COG2982	Protein involved in outer membrane biogenesis
BRPE64_RS07375	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BRPE64_RS07380	COG0390	transport system, permease component
BRPE64_RS07395	COG5002	protein histidine kinase activity
BRPE64_RS07400	COG0784	Response regulator, receiver
BRPE64_RS07405	COG4251	negative regulation of phosphorylation
BRPE64_RS07435	COG0604	alcohol dehydrogenase
BRPE64_RS07440	COG0583	DNA-binding transcription factor activity
BRPE64_RS07445	COG0560	Phosphoserine phosphatase
BRPE64_RS07450	COG0626	cystathionine gamma-synthase activity
BRPE64_RS07460	COG0183	Belongs to the thiolase family
BRPE64_RS07465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRPE64_RS07470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BRPE64_RS07480	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS07485	COG0183	Belongs to the thiolase family
BRPE64_RS07490	COG3243	poly(R)-hydroxyalkanoic acid synthase
BRPE64_RS07500	COG0564	pseudouridine synthase activity
BRPE64_RS07510	COG1199	ATP-dependent helicase activity
BRPE64_RS07525	COG2183	response to ionizing radiation
BRPE64_RS07530	COG3158	transport of potassium into the cell
BRPE64_RS07535	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BRPE64_RS07545	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BRPE64_RS07560	COG0330	HflC and HflK could
BRPE64_RS07565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BRPE64_RS07575	COG1160	GTP binding
BRPE64_RS07580	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BRPE64_RS07590	COG0124	histidyl-tRNA synthetase
BRPE64_RS07595	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BRPE64_RS07610	COG0105	UTP biosynthetic process
BRPE64_RS07615	COG0670	Belongs to the BI1 family
BRPE64_RS07640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BRPE64_RS07640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BRPE64_RS07645	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BRPE64_RS07660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BRPE64_RS07675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BRPE64_RS07685	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BRPE64_RS07690	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BRPE64_RS07705	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BRPE64_RS07710	COG3228	Belongs to the MtfA family
BRPE64_RS07715	COG0254	rRNA binding
BRPE64_RS07730	COG2373	Large extracellular alpha-helical protein
BRPE64_RS07735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BRPE64_RS07750	COG0542	response to heat
BRPE64_RS07755	COG1959	2 iron, 2 sulfur cluster binding
BRPE64_RS07765	COG0314	molybdopterin synthase activity
BRPE64_RS07770	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BRPE64_RS07780	COG1051	belongs to the nudix hydrolase family
BRPE64_RS07785	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BRPE64_RS07790	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BRPE64_RS07795	COG0167	dihydroorotate dehydrogenase activity
BRPE64_RS07800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS07805	COG0765	amino acid transport
BRPE64_RS07810	COG0673	inositol 2-dehydrogenase activity
BRPE64_RS07845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BRPE64_RS07850	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BRPE64_RS07875	COG3121	Chaperone
BRPE64_RS07880	COG3023	N-Acetylmuramoyl-L-alanine amidase
BRPE64_RS07885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BRPE64_RS07890	COG0557	exoribonuclease II activity
BRPE64_RS07905	COG0477	Major facilitator Superfamily
BRPE64_RS07915	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS07920	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS07930	COG0183	Belongs to the thiolase family
BRPE64_RS07935	COG0318	PFAM AMP-dependent synthetase and ligase
BRPE64_RS07965	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BRPE64_RS07970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BRPE64_RS07975	COG0508	dehydrogenase complex catalyzes the overall conversion of
BRPE64_RS07980	COG0567	Dehydrogenase, E1 component
BRPE64_RS08000	COG1566	PFAM secretion protein HlyD family protein
BRPE64_RS08005	COG2814	Major facilitator Superfamily
BRPE64_RS08010	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BRPE64_RS08015	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BRPE64_RS08025	COG2251	uridine kinase activity
BRPE64_RS08025	COG0195	Participates in both transcription termination and antitermination
BRPE64_RS08030	COG0779	Required for maturation of 30S ribosomal subunits
BRPE64_RS08040	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BRPE64_RS08045	COG0436	Aminotransferase
BRPE64_RS08050	COG0583	DNA-binding transcription factor activity
BRPE64_RS08120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BRPE64_RS08130	COG1752	Esterase of the alpha-beta hydrolase superfamily
BRPE64_RS08135	COG2010	Cytochrome c
BRPE64_RS08135	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BRPE64_RS08150	COG2975	iron-sulfur cluster assembly
BRPE64_RS08165	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BRPE64_RS08175	COG0822	iron-sulfur transferase activity
BRPE64_RS08180	COG1104	cysteine desulfurase activity
BRPE64_RS08190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BRPE64_RS08200	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS08205	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BRPE64_RS08235	COG0587	DNA-directed DNA polymerase activity
BRPE64_RS08290	COG2866	Carboxypeptidase
BRPE64_RS08295	COG3022	response to hydroperoxide
BRPE64_RS08305	COG0436	Aminotransferase
BRPE64_RS08310	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRPE64_RS08315	COG1024	Enoyl-CoA hydratase
BRPE64_RS08320	COG0588	phosphoglycerate mutase activity
BRPE64_RS08330	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS08355	COG0494	nUDIX hydrolase
BRPE64_RS08365	COG1007	ATP synthesis coupled electron transport
BRPE64_RS08380	COG0713	ATP synthesis coupled electron transport
BRPE64_RS08390	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BRPE64_RS08395	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BRPE64_RS08400	COG1034	ATP synthesis coupled electron transport
BRPE64_RS08405	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BRPE64_RS08410	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BRPE64_RS08415	COG0649	NAD binding
BRPE64_RS08420	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BRPE64_RS08425	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BRPE64_RS08430	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BRPE64_RS08445	COG0149	triose-phosphate isomerase activity
BRPE64_RS08450	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS08450	COG0604	alcohol dehydrogenase
BRPE64_RS08450	COG3321	synthase
BRPE64_RS08455	COG1185	polyribonucleotide nucleotidyltransferase activity
BRPE64_RS08460	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BRPE64_RS08465	COG0683	leucine binding
BRPE64_RS08475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BRPE64_RS08480	COG0791	NLP P60 protein
BRPE64_RS08485	COG4172	Belongs to the ABC transporter superfamily
BRPE64_RS08490	COG4239	(ABC) transporter, permease
BRPE64_RS08495	COG4174	ABC transporter (Permease)
BRPE64_RS08500	COG4166	transmembrane transport
BRPE64_RS08540	COG3052	prosthetic group binding
BRPE64_RS08565	COG0501	Belongs to the peptidase M48B family
BRPE64_RS08580	COG0527	aspartate kinase activity
BRPE64_RS08585	COG0037	tRNA processing
BRPE64_RS08590	COG0825	malonyl-CoA metabolic process
BRPE64_RS08595	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BRPE64_RS08600	COG0215	cysteine-tRNA ligase activity
BRPE64_RS08615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BRPE64_RS08620	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BRPE64_RS08625	COG1045	serine acetyltransferase
BRPE64_RS08635	COG0483	inositol monophosphate 1-phosphatase activity
BRPE64_RS08650	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BRPE64_RS08665	COG2850	peptidyl-arginine hydroxylation
BRPE64_RS08675	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BRPE64_RS08680	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BRPE64_RS08685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BRPE64_RS08695	COG0180	Tryptophanyl-tRNA synthetase
BRPE64_RS08700	COG1994	Peptidase M50
BRPE64_RS08705	COG0009	L-threonylcarbamoyladenylate synthase
BRPE64_RS08710	COG0613	PHP domain protein
BRPE64_RS08715	COG0596	Alpha beta hydrolase
BRPE64_RS08720	COG2833	Protein of unknown function (DUF455)
BRPE64_RS08730	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BRPE64_RS08740	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BRPE64_RS08750	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BRPE64_RS08755	COG0504	CTP synthase activity
BRPE64_RS08770	COG0084	hydrolase, TatD family'
BRPE64_RS08775	COG1136	(ABC) transporter
BRPE64_RS08790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BRPE64_RS08815	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BRPE64_RS08830	COG1183	phosphatidylcholine synthase activity
BRPE64_RS08835	COG0688	phosphatidylethanolamine metabolic process
BRPE64_RS08840	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BRPE64_RS08845	COG0440	acetolactate synthase activity
BRPE64_RS08850	COG0028	Belongs to the TPP enzyme family
BRPE64_RS08880	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS08900	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS08920	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BRPE64_RS08930	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BRPE64_RS08945	COG1271	oxidase subunit
BRPE64_RS08950	COG1294	oxidase, subunit
BRPE64_RS08965	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BRPE64_RS08970	COG5001	Diguanylate cyclase
BRPE64_RS08970	COG3300	MHYT domain
BRPE64_RS08985	COG0840	transmembrane signaling receptor activity
BRPE64_RS08990	COG2223	nitrite transmembrane transporter activity
BRPE64_RS08995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BRPE64_RS09015	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BRPE64_RS09020	COG0210	DNA helicase
BRPE64_RS09025	COG0525	valine-tRNA ligase activity
BRPE64_RS09030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BRPE64_RS09035	COG0425	Belongs to the sulfur carrier protein TusA family
BRPE64_RS09040	COG0673	inositol 2-dehydrogenase activity
BRPE64_RS09045	COG0673	inositol 2-dehydrogenase activity
BRPE64_RS09060	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS09065	COG1129	ABC transporter
BRPE64_RS09075	COG3962	Belongs to the TPP enzyme family
BRPE64_RS09085	COG3718	enzyme involved in inositol metabolism
BRPE64_RS09095	COG1137	ATPase activity
BRPE64_RS09110	COG0824	Thioesterase
BRPE64_RS09125	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BRPE64_RS09135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BRPE64_RS09145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BRPE64_RS09150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS09155	COG0494	nUDIX hydrolase
BRPE64_RS09165	COG1858	cytochrome C peroxidase
BRPE64_RS09185	COG2807	transmembrane transport
BRPE64_RS09205	COG1968	undecaprenyl-diphosphatase activity
BRPE64_RS09215	COG4942	peptidase
BRPE64_RS09260	COG0745	RESPONSE REGULATOR receiver
BRPE64_RS09275	COG0581	inorganic phosphate transmembrane transporter activity
BRPE64_RS09280	COG0573	inorganic phosphate transmembrane transporter activity
BRPE64_RS09285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BRPE64_RS09290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BRPE64_RS09295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BRPE64_RS09300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BRPE64_RS09310	COG1534	Rna-binding protein
BRPE64_RS09320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BRPE64_RS09325	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BRPE64_RS09330	COG0505	Belongs to the CarA family
BRPE64_RS09340	COG1388	LysM domain
BRPE64_RS09340	COG0741	lytic transglycosylase activity
BRPE64_RS09345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRPE64_RS09350	COG2226	methyltransferase
BRPE64_RS09355	COG0328	RNA-DNA hybrid ribonuclease activity
BRPE64_RS09360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BRPE64_RS09380	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS09390	COG1132	(ABC) transporter
BRPE64_RS09395	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BRPE64_RS09405	COG1999	signal sequence binding
BRPE64_RS09415	COG2153	protein acetylation
BRPE64_RS09435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BRPE64_RS09440	COG0322	excinuclease ABC activity
BRPE64_RS09450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BRPE64_RS09460	COG2204	response regulator
BRPE64_RS09465	COG1472	Belongs to the glycosyl hydrolase 3 family
BRPE64_RS09470	COG0736	holo-[acyl-carrier-protein] synthase activity
BRPE64_RS09480	COG1381	Involved in DNA repair and RecF pathway recombination
BRPE64_RS09485	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BRPE64_RS09490	COG0571	ribonuclease III activity
BRPE64_RS09495	COG0681	Belongs to the peptidase S26 family
BRPE64_RS09500	COG0481	GTPase activity
BRPE64_RS09510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BRPE64_RS09525	COG1595	DNA-templated transcription, initiation
BRPE64_RS09535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BRPE64_RS09565	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BRPE64_RS09570	COG1399	metal-binding, possibly nucleic acid-binding protein
BRPE64_RS09575	COG0424	maF-like protein
BRPE64_RS09585	COG0616	signal peptide processing
BRPE64_RS09585	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BRPE64_RS09605	COG1530	ribonuclease E activity
BRPE64_RS09610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BRPE64_RS09620	COG0303	'Molybdopterin
BRPE64_RS09635	COG1322	Protein conserved in bacteria
BRPE64_RS09660	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BRPE64_RS09685	COG1139	Iron-sulfur cluster binding protein
BRPE64_RS09690	COG0247	lactate metabolic process
BRPE64_RS09700	COG3045	CreA protein
BRPE64_RS09710	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BRPE64_RS09745	COG0534	Mate efflux family protein
BRPE64_RS09750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BRPE64_RS09755	COG0114	fumarate hydratase activity
BRPE64_RS09795	COG0312	modulator of DNA gyrase
BRPE64_RS09800	COG3028	Belongs to the UPF0307 family
BRPE64_RS09805	COG0521	Mo-molybdopterin cofactor biosynthetic process
BRPE64_RS09810	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BRPE64_RS09815	COG0501	Belongs to the peptidase M48B family
BRPE64_RS09830	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BRPE64_RS09845	COG0336	Belongs to the RNA methyltransferase TrmD family
BRPE64_RS09850	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BRPE64_RS09880	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS09900	COG2011	ABC-type metal ion transport system permease component
BRPE64_RS09910	COG2267	carboxylic ester hydrolase activity
BRPE64_RS09915	COG0123	including yeast histone deacetylase and acetoin utilization protein
BRPE64_RS09920	COG2951	lytic endotransglycosylase activity
BRPE64_RS09930	COG1555	photosystem II stabilization
BRPE64_RS09930	COG1596	polysaccharide export
BRPE64_RS09935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRPE64_RS09940	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BRPE64_RS09950	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BRPE64_RS09960	COG0776	regulation of translation
BRPE64_RS09980	COG0287	Prephenate dehydrogenase
BRPE64_RS09985	COG1605	Chorismate mutase
BRPE64_RS09985	COG0077	Prephenate dehydratase
BRPE64_RS10010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BRPE64_RS10015	COG0546	phosphoglycolate phosphatase activity
BRPE64_RS10025	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS10035	COG1910	domain protein
BRPE64_RS10050	COG3383	formate dehydrogenase (NAD+) activity
BRPE64_RS10070	COG0640	Transcriptional regulator
BRPE64_RS10080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS10110	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BRPE64_RS10115	COG4651	solute:proton antiporter activity
BRPE64_RS10115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BRPE64_RS10120	COG0347	Belongs to the P(II) protein family
BRPE64_RS10135	COG2827	Endonuclease containing a URI domain
BRPE64_RS10140	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BRPE64_RS10145	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS10155	COG2271	Major facilitator Superfamily
BRPE64_RS10180	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BRPE64_RS10215	COG0765	amino acid transport
BRPE64_RS10220	COG0765	amino acid transport
BRPE64_RS10225	COG1126	abc transporter atp-binding protein
BRPE64_RS10230	COG0831	urea catabolic process
BRPE64_RS10235	COG0832	Belongs to the urease beta subunit family
BRPE64_RS10245	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BRPE64_RS10250	COG0830	nickel cation binding
BRPE64_RS10255	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BRPE64_RS10320	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS10325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BRPE64_RS10330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BRPE64_RS10345	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS10350	COG2244	polysaccharide biosynthetic process
BRPE64_RS10395	COG0297	glycogen (starch) synthase activity
BRPE64_RS10400	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS10405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRPE64_RS10410	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BRPE64_RS10415	COG0489	protein tyrosine kinase activity
BRPE64_RS10415	COG3206	protein involved in exopolysaccharide biosynthesis
BRPE64_RS10430	COG0662	Cupin 2, conserved barrel domain protein
BRPE64_RS10430	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BRPE64_RS10450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BRPE64_RS10480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BRPE64_RS10535	COG1216	Glycosyl transferase, family 2
BRPE64_RS10550	COG1442	glycosyl transferase family 8
BRPE64_RS10550	COG1216	Glycosyl transferase, family 2
BRPE64_RS10565	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS10565	COG1216	Glycosyl transferase, family 2
BRPE64_RS10570	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS10570	COG1216	Glycosyl transferase, family 2
BRPE64_RS10620	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BRPE64_RS10625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BRPE64_RS10630	COG1678	Uncharacterized ACR, COG1678
BRPE64_RS10635	COG0415	Belongs to the DNA photolyase family
BRPE64_RS10645	COG1773	rubredoxin
BRPE64_RS10665	COG0459	protein refolding
BRPE64_RS10670	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BRPE64_RS10715	COG0583	DNA-binding transcription factor activity
BRPE64_RS10720	COG2207	Transcriptional regulator
BRPE64_RS10730	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BRPE64_RS10745	COG2188	Transcriptional regulator
BRPE64_RS10750	COG2814	Major facilitator Superfamily
BRPE64_RS10760	COG0546	phosphoglycolate phosphatase activity
BRPE64_RS10760	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BRPE64_RS10780	COG1570	exodeoxyribonuclease VII activity
BRPE64_RS10790	COG2835	tetraacyldisaccharide 4'-kinase activity
BRPE64_RS10800	COG0563	adenylate kinase activity
BRPE64_RS10815	COG0728	peptidoglycan biosynthetic process
BRPE64_RS10820	COG0268	Binds directly to 16S ribosomal RNA
BRPE64_RS10830	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BRPE64_RS10835	COG0137	argininosuccinate synthase activity
BRPE64_RS10850	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BRPE64_RS10855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BRPE64_RS10860	COG4974	Belongs to the 'phage' integrase family
BRPE64_RS10865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BRPE64_RS10870	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BRPE64_RS10875	COG0802	atpase or kinase
BRPE64_RS10880	COG0860	N-Acetylmuramoyl-L-alanine amidase
BRPE64_RS10895	COG1741	Belongs to the pirin family
BRPE64_RS10905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BRPE64_RS10910	COG0259	pyridoxamine-phosphate oxidase activity
BRPE64_RS10915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BRPE64_RS10925	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BRPE64_RS10930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BRPE64_RS10935	COG1522	sequence-specific DNA binding
BRPE64_RS10940	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BRPE64_RS10950	COG3483	tryptophan 2,3-dioxygenase activity
BRPE64_RS10960	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS11015	COG4221	oxidoreductase activity
BRPE64_RS11020	COG0824	Thioesterase
BRPE64_RS11040	COG0823	Involved in the tonB-independent uptake of proteins
BRPE64_RS11045	COG2885	chlorophyll binding
BRPE64_RS11070	COG0420	3'-5' exonuclease activity
BRPE64_RS11080	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BRPE64_RS11085	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BRPE64_RS11090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BRPE64_RS11095	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BRPE64_RS11100	COG3178	'Phosphotransferase
BRPE64_RS11105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BRPE64_RS11115	COG3265	gluconokinase activity
BRPE64_RS11125	COG0800	Aldolase
BRPE64_RS11140	COG1981	membrane
BRPE64_RS11145	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BRPE64_RS11155	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BRPE64_RS11175	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BRPE64_RS11180	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BRPE64_RS11185	COG0735	belongs to the Fur family
BRPE64_RS11190	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BRPE64_RS11195	COG4266	Belongs to the allantoicase family
BRPE64_RS11200	COG1301	dicarboxylic acid transport
BRPE64_RS11215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BRPE64_RS11220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BRPE64_RS11230	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BRPE64_RS11275	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BRPE64_RS11280	COG1546	Belongs to the CinA family
BRPE64_RS11285	COG0284	orotidine-5'-phosphate decarboxylase activity
BRPE64_RS11305	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS11310	COG1129	ABC transporter
BRPE64_RS11320	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS11325	COG0800	Aldolase
BRPE64_RS11330	COG3734	2-keto-3-deoxy-galactonokinase
BRPE64_RS11335	COG1414	Transcriptional regulator
BRPE64_RS11340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BRPE64_RS11345	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BRPE64_RS11350	COG0557	exoribonuclease II activity
BRPE64_RS11355	COG3150	esterase
BRPE64_RS11360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BRPE64_RS11370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRPE64_RS11375	COG0511	ligase activity, forming carbon-carbon bonds
BRPE64_RS11380	COG0439	Biotin carboxylase
BRPE64_RS11395	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BRPE64_RS11400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRPE64_RS11430	COG0477	Major facilitator Superfamily
BRPE64_RS11435	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BRPE64_RS11435	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BRPE64_RS11450	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BRPE64_RS11455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BRPE64_RS11460	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BRPE64_RS11465	COG2095	MarC family integral membrane protein
BRPE64_RS11470	COG0442	prolyl-tRNA aminoacylation
BRPE64_RS11475	COG0494	nUDIX hydrolase
BRPE64_RS11485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BRPE64_RS11500	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BRPE64_RS11505	COG0142	geranyltranstransferase activity
BRPE64_RS11515	COG4536	flavin adenine dinucleotide binding
BRPE64_RS11520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BRPE64_RS11540	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BRPE64_RS11545	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BRPE64_RS11550	COG0494	nUDIX hydrolase
BRPE64_RS11565	COG0653	protein targeting
BRPE64_RS11575	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BRPE64_RS11580	COG0678	peroxiredoxin activity
BRPE64_RS11595	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BRPE64_RS11600	COG1181	Belongs to the D-alanine--D-alanine ligase family
BRPE64_RS11605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BRPE64_RS11610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BRPE64_RS11630	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BRPE64_RS11635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BRPE64_RS11645	COG3116	cell division
BRPE64_RS11650	COG0275	rRNA processing
BRPE64_RS11660	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BRPE64_RS11665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BRPE64_RS11670	COG0318	PFAM AMP-dependent synthetase and ligase
BRPE64_RS11675	COG0243	molybdopterin cofactor binding
BRPE64_RS11680	COG1473	amidohydrolase
BRPE64_RS11705	COG1024	Enoyl-CoA hydratase
BRPE64_RS11715	COG1024	Enoyl-CoA hydratase
BRPE64_RS11720	COG2050	protein possibly involved in aromatic compounds catabolism
BRPE64_RS11730	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BRPE64_RS11740	COG2967	ApaG domain
BRPE64_RS11745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BRPE64_RS11750	COG0546	phosphoglycolate phosphatase activity
BRPE64_RS11770	COG0134	indole-3-glycerol-phosphate synthase activity
BRPE64_RS11775	COG3025	triphosphatase activity
BRPE64_RS11780	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BRPE64_RS11795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BRPE64_RS11800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BRPE64_RS11805	COG0012	GTP binding
BRPE64_RS11815	COG0488	(ABC) transporter
BRPE64_RS11835	COG0006	proline dipeptidase activity
BRPE64_RS11845	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BRPE64_RS11850	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BRPE64_RS11855	COG2890	protein-(glutamine-N5) methyltransferase activity
BRPE64_RS11860	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BRPE64_RS11870	COG3384	dioxygenase
BRPE64_RS11875	COG0531	amino acid
BRPE64_RS11880	COG1278	Cold shock
BRPE64_RS11885	COG0443	Heat shock 70 kDa protein
BRPE64_RS11890	COG0477	Major facilitator Superfamily
BRPE64_RS11895	COG0778	Nitroreductase
BRPE64_RS11925	COG2186	Transcriptional regulator
BRPE64_RS11930	COG0246	Mannitol dehydrogenase
BRPE64_RS11935	COG2271	Major facilitator Superfamily
BRPE64_RS11940	COG2721	sulfolactate sulfo-lyase activity
BRPE64_RS11945	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BRPE64_RS11975	COG2969	positive regulation of protein catabolic process
BRPE64_RS11980	COG0625	glutathione transferase activity
BRPE64_RS11985	COG2857	Cytochrome c1
BRPE64_RS11990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BRPE64_RS11995	COG0723	plastoquinol--plastocyanin reductase activity
BRPE64_RS12000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BRPE64_RS12010	COG0805	protein transport
BRPE64_RS12015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BRPE64_RS12020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BRPE64_RS12035	COG0140	phosphoribosyl-ATP diphosphatase activity
BRPE64_RS12040	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BRPE64_RS12045	COG0107	imidazoleglycerol-phosphate synthase activity
BRPE64_RS12050	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BRPE64_RS12060	COG2095	MarC family integral membrane protein
BRPE64_RS12085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BRPE64_RS12090	COG0271	Belongs to the BolA IbaG family
BRPE64_RS12095	COG0842	Transport permease protein
BRPE64_RS12100	COG1131	(ABC) transporter
BRPE64_RS12115	COG2853	Lipoprotein
BRPE64_RS12120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BRPE64_RS12125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BRPE64_RS12130	COG1127	ABC transporter
BRPE64_RS12155	COG4178	(ABC) transporter
BRPE64_RS12165	COG0067	glutamate synthase
BRPE64_RS12165	COG0070	glutamate synthase
BRPE64_RS12165	COG0069	glutamate synthase activity
BRPE64_RS12185	COG0584	glycerophosphoryl diester phosphodiesterase
BRPE64_RS12190	COG3842	ATPase activity
BRPE64_RS12200	COG0395	ABC-type sugar transport system, permease component
BRPE64_RS12210	COG1653	transport
BRPE64_RS12215	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BRPE64_RS12255	COG1965	Belongs to the frataxin family
BRPE64_RS12265	COG0019	diaminopimelate decarboxylase activity
BRPE64_RS12270	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BRPE64_RS12275	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BRPE64_RS12280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BRPE64_RS12285	COG1333	cytochrome c biogenesis protein
BRPE64_RS12295	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BRPE64_RS12305	COG4232	protein-disulfide reductase activity
BRPE64_RS12320	COG0202	RNA polymerase activity
BRPE64_RS12330	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BRPE64_RS12335	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BRPE64_RS12350	COG0201	protein transport
BRPE64_RS12355	COG0200	Binds to the 23S rRNA
BRPE64_RS12365	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BRPE64_RS12375	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BRPE64_RS12380	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BRPE64_RS12390	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BRPE64_RS12400	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BRPE64_RS12405	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BRPE64_RS12410	COG0255	Belongs to the universal ribosomal protein uL29 family
BRPE64_RS12420	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BRPE64_RS12425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BRPE64_RS12435	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BRPE64_RS12440	COG0089	rRNA binding
BRPE64_RS12445	COG0088	Forms part of the polypeptide exit tunnel
BRPE64_RS12450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BRPE64_RS12455	COG0051	transcription antitermination factor activity, RNA binding
BRPE64_RS12465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BRPE64_RS12470	COG0049	tRNA binding
BRPE64_RS12475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BRPE64_RS12480	COG0514	ATP-dependent DNA helicase (RecQ)
BRPE64_RS12485	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BRPE64_RS12490	COG0085	RNA polymerase activity
BRPE64_RS12495	COG0222	ribosome binding
BRPE64_RS12500	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BRPE64_RS12505	COG0081	regulation of translation
BRPE64_RS12510	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BRPE64_RS12520	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BRPE64_RS12575	COG2813	Specifically methylates the guanine in position
BRPE64_RS12585	COG2271	Major facilitator Superfamily
BRPE64_RS12590	COG3396	Phenylacetate-CoA oxygenase
BRPE64_RS12595	COG3460	Phenylacetate-CoA oxygenase
BRPE64_RS12600	COG3396	Phenylacetate-CoA oxygenase
BRPE64_RS12605	COG2151	metal-sulfur cluster biosynthetic enzyme
BRPE64_RS12610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BRPE64_RS12630	COG1522	sequence-specific DNA binding
BRPE64_RS12655	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BRPE64_RS12660	COG2197	response regulator
BRPE64_RS12665	COG1881	PFAM PEBP family protein
BRPE64_RS12675	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BRPE64_RS12690	COG1280	lysine exporter protein (LysE YggA)
BRPE64_RS12695	COG2084	Dehydrogenase
BRPE64_RS12725	COG0579	oxidoreductase
BRPE64_RS12730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BRPE64_RS12740	COG3568	Endonuclease Exonuclease Phosphatase
BRPE64_RS12745	COG0745	RESPONSE REGULATOR receiver
BRPE64_RS12755	COG0251	oxidation-reduction process
BRPE64_RS12760	COG1285	pathogenesis
BRPE64_RS12800	COG2084	Dehydrogenase
BRPE64_RS12815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BRPE64_RS12820	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BRPE64_RS12825	COG0037	tRNA processing
BRPE64_RS12835	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS12855	COG0617	tRNA 3'-terminal CCA addition
BRPE64_RS12870	COG0741	lytic transglycosylase activity
BRPE64_RS12875	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BRPE64_RS12885	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BRPE64_RS12890	COG1984	allophanate hydrolase subunit 2
BRPE64_RS12895	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BRPE64_RS12910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BRPE64_RS12960	COG4608	Belongs to the ABC transporter superfamily
BRPE64_RS12965	COG0444	Belongs to the ABC transporter superfamily
BRPE64_RS12970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRPE64_RS12975	COG0601	transmembrane transport
BRPE64_RS12980	COG0747	negative chemotaxis
BRPE64_RS12985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BRPE64_RS12990	COG1950	PFAM Membrane protein of
BRPE64_RS12995	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BRPE64_RS13000	COG1215	transferase activity, transferring glycosyl groups
BRPE64_RS13010	COG1380	Effector of murein hydrolase LrgA
BRPE64_RS13015	COG0583	DNA-binding transcription factor activity
BRPE64_RS13020	COG2885	chlorophyll binding
BRPE64_RS13020	COG3047	cAMP biosynthetic process
BRPE64_RS13025	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS13030	COG2257	FlhB HrpN YscU SpaS Family
BRPE64_RS13045	COG1516	flagellar protein fliS
BRPE64_RS13085	COG1580	Controls the rotational direction of flagella during chemotaxis
BRPE64_RS13095	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BRPE64_RS13105	COG1338	Plays a role in the flagellum-specific transport system
BRPE64_RS13110	COG1987	bacterial-type flagellum assembly
BRPE64_RS13120	COG0457	Tetratricopeptide repeat
BRPE64_RS13120	COG0859	PFAM glycosyl transferase family 9
BRPE64_RS13135	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BRPE64_RS13145	COG1706	bacterial-type flagellum-dependent cell motility
BRPE64_RS13160	COG4787	bacterial-type flagellum-dependent cell motility
BRPE64_RS13170	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BRPE64_RS13175	COG1558	bacterial-type flagellum-dependent cell motility
BRPE64_RS13205	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BRPE64_RS13210	COG1760	l-serine dehydratase
BRPE64_RS13225	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BRPE64_RS13225	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BRPE64_RS13230	COG0509	glycine decarboxylation via glycine cleavage system
BRPE64_RS13245	COG0673	inositol 2-dehydrogenase activity
BRPE64_RS13250	COG0210	DNA helicase
BRPE64_RS13255	COG3245	cytochrome
BRPE64_RS13275	COG1191	sigma factor activity
BRPE64_RS13290	COG0028	Belongs to the TPP enzyme family
BRPE64_RS13305	COG0683	leucine binding
BRPE64_RS13310	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BRPE64_RS13310	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BRPE64_RS13310	COG0506	proline dehydrogenase activity
BRPE64_RS13315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BRPE64_RS13325	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BRPE64_RS13335	COG0657	acetylesterase activity
BRPE64_RS13340	COG0318	PFAM AMP-dependent synthetase and ligase
BRPE64_RS13345	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BRPE64_RS13350	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BRPE64_RS13355	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BRPE64_RS13365	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BRPE64_RS13370	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BRPE64_RS13380	COG0356	it plays a direct role in the translocation of protons across the membrane
BRPE64_RS13390	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BRPE64_RS13395	COG1475	DNA binding
BRPE64_RS13400	COG1192	Involved in chromosome partitioning
BRPE64_RS13405	COG0357	Ribosomal RNA small subunit methyltransferase G
BRPE64_RS13410	COG0445	tRNA wobble uridine modification
BRPE64_RS13470	COG0583	DNA-binding transcription factor activity
BRPE64_RS13480	COG1522	sequence-specific DNA binding
BRPE64_RS13495	COG0642	Histidine kinase
BRPE64_RS13505	COG1902	pentaerythritol trinitrate reductase activity
BRPE64_RS13510	COG0519	Catalyzes the synthesis of GMP from XMP
BRPE64_RS13510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BRPE64_RS13520	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BRPE64_RS13530	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BRPE64_RS13530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRPE64_RS13550	COG0741	lytic transglycosylase activity
BRPE64_RS13625	COG1846	Transcriptional regulator
BRPE64_RS13630	COG2814	Major facilitator Superfamily
BRPE64_RS13640	COG2918	glutathione biosynthetic process
BRPE64_RS13645	COG2169	Transcriptional regulator
BRPE64_RS13645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BRPE64_RS13650	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BRPE64_RS13655	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BRPE64_RS13665	COG0523	cobalamin synthesis protein
BRPE64_RS13670	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BRPE64_RS13675	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BRPE64_RS13685	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BRPE64_RS13690	COG1560	Kdo2-lipid A biosynthetic process
BRPE64_RS13695	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BRPE64_RS13700	COG1902	pentaerythritol trinitrate reductase activity
BRPE64_RS13720	COG0668	transmembrane transport
BRPE64_RS13725	COG0667	Aldo Keto reductase
BRPE64_RS13735	COG4585	Histidine kinase
BRPE64_RS13745	COG0531	amino acid
BRPE64_RS13780	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BRPE64_RS13790	COG3645	SOS response
BRPE64_RS13810	COG2814	Major facilitator Superfamily
BRPE64_RS13840	COG2916	Histone family protein nucleoid-structuring protein H-NS
BRPE64_RS13850	COG1522	sequence-specific DNA binding
BRPE64_RS13860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRPE64_RS13865	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BRPE64_RS13875	COG0792	nuclease activity
BRPE64_RS13880	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BRPE64_RS13915	COG1280	lysine exporter protein (LysE YggA)
BRPE64_RS14005	COG0582	viral genome integration into host DNA
BRPE64_RS14010	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BRPE64_RS14020	COG0706	membrane insertase activity
BRPE64_RS14025	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BRPE64_RS14030	COG0594	ribonuclease P activity
BRPE64_RS14050	COG1192	Involved in chromosome partitioning
BRPE64_RS14090	COG1396	sequence-specific DNA binding
BRPE64_RS14100	COG1063	alcohol dehydrogenase
BRPE64_RS14105	COG2353	YceI-like domain
BRPE64_RS14115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRPE64_RS14145	COG1473	amidohydrolase
BRPE64_RS14180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BRPE64_RS14200	COG0642	Histidine kinase
BRPE64_RS14220	COG0583	DNA-binding transcription factor activity
BRPE64_RS14230	COG0477	Major facilitator Superfamily
BRPE64_RS14235	COG1414	Transcriptional regulator
BRPE64_RS14295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BRPE64_RS14305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BRPE64_RS14305	COG1017	nitric oxide dioxygenase activity
BRPE64_RS14310	COG0625	glutathione transferase activity
BRPE64_RS14325	COG0628	permease
BRPE64_RS14335	COG0840	transmembrane signaling receptor activity
BRPE64_RS14340	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS14345	COG2610	gluconate transmembrane transporter activity
BRPE64_RS14350	COG3604	Transcriptional regulator
BRPE64_RS14360	COG3040	lipid binding
BRPE64_RS14365	COG0679	Auxin Efflux Carrier
BRPE64_RS14385	COG0784	Response regulator, receiver
BRPE64_RS14385	COG4191	Histidine kinase
BRPE64_RS14395	COG2201	protein-glutamate methylesterase activity
BRPE64_RS14410	COG1562	ergosterol biosynthetic process
BRPE64_RS14415	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BRPE64_RS14420	COG1657	PFAM Prenyltransferase squalene oxidase
BRPE64_RS14435	COG2853	Lipoprotein
BRPE64_RS14460	COG1966	Carbon starvation protein
BRPE64_RS14465	COG2879	small protein
BRPE64_RS14480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BRPE64_RS14490	COG1215	transferase activity, transferring glycosyl groups
BRPE64_RS14505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRPE64_RS14510	COG4999	Histidine kinase
BRPE64_RS14510	COG3850	Histidine kinase
BRPE64_RS14510	COG3437	response regulator, receiver
BRPE64_RS14510	COG2205	protein histidine kinase activity
BRPE64_RS14515	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BRPE64_RS14530	COG1254	Belongs to the acylphosphatase family
BRPE64_RS14535	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BRPE64_RS14570	COG0477	Major facilitator Superfamily
BRPE64_RS14585	COG0484	heat shock protein binding
BRPE64_RS14630	COG3851	Histidine kinase
BRPE64_RS14640	COG0535	radical SAM domain protein
BRPE64_RS14650	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BRPE64_RS14655	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BRPE64_RS14660	COG3038	cytochrome b561
BRPE64_RS14665	COG2218	PFAM glutamate synthase alpha subunit domain protein
BRPE64_RS14670	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
BRPE64_RS14675	COG1229	Formylmethanofuran dehydrogenase subunit A
BRPE64_RS14685	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BRPE64_RS14730	COG1850	ribulose-bisphosphate carboxylase activity
BRPE64_RS14745	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BRPE64_RS14750	COG3954	Phosphoribulokinase
BRPE64_RS14755	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BRPE64_RS14760	COG0191	fructose-bisphosphate aldolase activity
BRPE64_RS14790	COG3284	Transcriptional regulator
BRPE64_RS14795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BRPE64_RS14805	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
BRPE64_RS14820	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
BRPE64_RS14830	COG0702	epimerase
BRPE64_RS14840	COG2154	pterin-4-alpha-carbinolamine dehydratase
BRPE64_RS14850	COG2010	Cytochrome c
BRPE64_RS14865	COG0583	DNA-binding transcription factor activity
BRPE64_RS14915	COG0457	Tetratricopeptide repeat
BRPE64_RS14920	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS14925	COG1596	polysaccharide export
BRPE64_RS14945	COG4783	chaperone-mediated protein folding
BRPE64_RS14945	COG1560	Kdo2-lipid A biosynthetic process
BRPE64_RS14965	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BRPE64_RS14970	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BRPE64_RS14975	COG3639	organic phosphonate transmembrane transporter activity
BRPE64_RS14990	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BRPE64_RS14995	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BRPE64_RS15000	COG2188	Transcriptional regulator
BRPE64_RS15005	COG3624	Phosphonate C-P lyase system protein PhnG
BRPE64_RS15015	COG3626	phosphonate metabolism
BRPE64_RS15020	COG3627	carbon phosphorus lyase activity
BRPE64_RS15025	COG4107	phosphonate C-P lyase system protein PhnK
BRPE64_RS15030	COG4778	phosphonate C-P lyase system protein PhnL
BRPE64_RS15035	COG3454	Phosphonate metabolism
BRPE64_RS15045	COG0840	transmembrane signaling receptor activity
BRPE64_RS15065	COG0583	DNA-binding transcription factor activity
BRPE64_RS15090	COG2205	protein histidine kinase activity
BRPE64_RS15105	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BRPE64_RS15110	COG0477	Major facilitator Superfamily
BRPE64_RS15115	COG0642	Histidine kinase
BRPE64_RS15120	COG0745	RESPONSE REGULATOR receiver
BRPE64_RS15135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BRPE64_RS15140	COG2175	clavaminate synthase activity
BRPE64_RS15155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BRPE64_RS15160	COG0583	DNA-binding transcription factor activity
BRPE64_RS15165	COG0667	Aldo Keto reductase
BRPE64_RS15170	COG2814	Major facilitator Superfamily
BRPE64_RS15190	COG2824	Alkylphosphonate utilization operon protein PhnA
BRPE64_RS15195	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS15220	COG0583	DNA-binding transcription factor activity
BRPE64_RS15225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BRPE64_RS15235	COG1802	Transcriptional regulator
BRPE64_RS15245	COG0045	succinate-CoA ligase (ADP-forming) activity
BRPE64_RS15250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BRPE64_RS15255	COG0179	Fumarylacetoacetate (FAA) hydrolase
BRPE64_RS15275	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BRPE64_RS15290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BRPE64_RS15305	COG0596	Alpha beta hydrolase
BRPE64_RS15310	COG0534	Mate efflux family protein
BRPE64_RS15315	COG1742	UPF0060 membrane protein
BRPE64_RS15325	COG0477	Major facilitator Superfamily
BRPE64_RS15340	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS15345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BRPE64_RS15350	COG1024	Enoyl-CoA hydratase
BRPE64_RS15355	COG1024	Enoyl-CoA hydratase
BRPE64_RS15370	COG0628	permease
BRPE64_RS15375	COG2010	Cytochrome c
BRPE64_RS15375	COG4993	Dehydrogenase
BRPE64_RS15410	COG1595	DNA-templated transcription, initiation
BRPE64_RS15420	COG0583	DNA-binding transcription factor activity
BRPE64_RS15440	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRPE64_RS15450	COG1131	(ABC) transporter
BRPE64_RS15455	COG0842	Transport permease protein
BRPE64_RS15465	COG1335	isochorismatase
BRPE64_RS15490	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BRPE64_RS15505	COG1473	amidohydrolase
BRPE64_RS15510	COG0840	transmembrane signaling receptor activity
BRPE64_RS15510	COG0840	transmembrane signaling receptor activity
BRPE64_RS15525	COG1573	uracil-dna glycosylase
BRPE64_RS15540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BRPE64_RS15545	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BRPE64_RS15550	COG2080	2 iron, 2 sulfur cluster binding
BRPE64_RS15590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS15590	COG2205	protein histidine kinase activity
BRPE64_RS15635	COG3842	ATPase activity
BRPE64_RS15650	COG0058	SHG alpha-glucan phosphorylase activity
BRPE64_RS15675	COG0640	Transcriptional regulator
BRPE64_RS15680	COG1902	pentaerythritol trinitrate reductase activity
BRPE64_RS15685	COG2985	domain, Protein
BRPE64_RS15695	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BRPE64_RS15720	COG1309	transcriptional regulator
BRPE64_RS15725	COG2271	Major facilitator Superfamily
BRPE64_RS15735	COG1309	transcriptional regulator
BRPE64_RS15740	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS15745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BRPE64_RS15750	COG4770	biotin carboxylase activity
BRPE64_RS15755	COG2885	chlorophyll binding
BRPE64_RS15775	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BRPE64_RS15790	COG3485	protocatechuate 3,4-dioxygenase
BRPE64_RS15795	COG3485	protocatechuate 3,4-dioxygenase
BRPE64_RS15800	COG0583	DNA-binding transcription factor activity
BRPE64_RS15805	COG0745	RESPONSE REGULATOR receiver
BRPE64_RS15820	COG2200	EAL domain
BRPE64_RS15820	COG2199	diguanylate cyclase activity
BRPE64_RS15835	COG5001	Diguanylate cyclase
BRPE64_RS15845	COG1940	carbohydrate kinase activity
BRPE64_RS15865	COG1228	amidohydrolase
BRPE64_RS15870	COG2261	transglycosylase associated protein
BRPE64_RS15880	COG2885	chlorophyll binding
BRPE64_RS15880	COG3047	cAMP biosynthetic process
BRPE64_RS15895	COG0583	DNA-binding transcription factor activity
BRPE64_RS15900	COG0668	transmembrane transport
BRPE64_RS15910	COG1446	asparaginase
BRPE64_RS15915	COG4172	Belongs to the ABC transporter superfamily
BRPE64_RS15920	COG0747	negative chemotaxis
BRPE64_RS15925	COG0601	transmembrane transport
BRPE64_RS15930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRPE64_RS15950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BRPE64_RS15960	COG2986	histidine ammonia-lyase
BRPE64_RS15995	COG1309	transcriptional regulator
BRPE64_RS16005	COG0493	'glutamate synthase
BRPE64_RS16015	COG1953	Uracil, thiamine, allantoin
BRPE64_RS16040	COG0540	Belongs to the ATCase OTCase family
BRPE64_RS16045	COG0432	Pfam Uncharacterised protein family UPF0047
BRPE64_RS16060	COG0330	HflC and HflK could
BRPE64_RS16070	COG0583	DNA-binding transcription factor activity
BRPE64_RS16075	COG1566	PFAM secretion protein HlyD family protein
BRPE64_RS16095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BRPE64_RS16100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRPE64_RS16115	COG1032	radical SAM domain protein
BRPE64_RS16160	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BRPE64_RS16190	COG2267	carboxylic ester hydrolase activity
BRPE64_RS16225	COG1942	4-Oxalocrotonate Tautomerase
BRPE64_RS16230	COG2091	lysine biosynthetic process via aminoadipic acid
BRPE64_RS16235	COG1451	nucleotide metabolic process
BRPE64_RS16255	COG2902	Dehydrogenase
BRPE64_RS16290	COG3128	pkhd-type hydroxylase
BRPE64_RS16295	COG4774	siderophore transport
BRPE64_RS16300	COG0583	DNA-binding transcription factor activity
BRPE64_RS16305	COG0457	Tetratricopeptide repeat
BRPE64_RS16310	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BRPE64_RS16315	COG1215	transferase activity, transferring glycosyl groups
BRPE64_RS16320	COG1215	transferase activity, transferring glycosyl groups
BRPE64_RS16325	COG0489	protein tyrosine kinase activity
BRPE64_RS16345	COG2910	NAD(P)H-binding
BRPE64_RS16355	COG1177	transmembrane transport
BRPE64_RS16360	COG1176	ABC-type spermidine putrescine transport system, permease component I
BRPE64_RS16370	COG3842	ATPase activity
BRPE64_RS16385	COG3121	Chaperone
BRPE64_RS16400	COG2274	protein secretion by the type I secretion system
BRPE64_RS16405	COG1538	Outer membrane efflux protein
BRPE64_RS16430	COG0745	RESPONSE REGULATOR receiver
BRPE64_RS16440	COG0835	chemotaxis
BRPE64_RS16440	COG0784	Response regulator, receiver
BRPE64_RS16445	COG0517	IMP dehydrogenase activity
BRPE64_RS16455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BRPE64_RS16460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BRPE64_RS16470	COG0400	carboxylic ester hydrolase activity
BRPE64_RS16485	COG0443	Heat shock 70 kDa protein
BRPE64_RS16490	COG0443	Heat shock 70 kDa protein
BRPE64_RS16505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BRPE64_RS16505	COG1116	anion transmembrane transporter activity
BRPE64_RS16510	COG3707	response regulator
BRPE64_RS16525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BRPE64_RS16530	COG2146	nitrite reductase [NAD(P)H] activity
BRPE64_RS16535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BRPE64_RS16540	COG0243	molybdopterin cofactor binding
BRPE64_RS16575	COG1538	Outer membrane efflux protein
BRPE64_RS16580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRPE64_RS16600	COG1914	H( )-stimulated, divalent metal cation uptake system
BRPE64_RS16630	COG1360	Flagellar Motor Protein
BRPE64_RS16660	COG0745	RESPONSE REGULATOR receiver
BRPE64_RS16665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BRPE64_RS16710	COG2205	protein histidine kinase activity
BRPE64_RS16710	COG0784	Response regulator, receiver
BRPE64_RS16735	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS16740	COG2271	Major facilitator Superfamily
BRPE64_RS16745	COG4948	Mandelate Racemase Muconate Lactonizing
BRPE64_RS16750	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS16760	COG3254	rhamnose metabolic process
BRPE64_RS16765	COG3618	amidohydrolase
BRPE64_RS16770	COG1129	ABC transporter
BRPE64_RS16785	COG1879	ABC-type sugar transport system periplasmic component
BRPE64_RS16810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BRPE64_RS16825	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BRPE64_RS16830	COG2116	formate transmembrane transporter activity
BRPE64_RS16865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BRPE64_RS16870	COG1940	carbohydrate kinase activity
BRPE64_RS16880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BRPE64_RS16885	COG0598	Magnesium transport protein CorA
BRPE64_RS16900	COG0739	heme binding
BRPE64_RS16930	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS16940	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BRPE64_RS16945	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BRPE64_RS16965	COG2271	Major facilitator Superfamily
BRPE64_RS16980	COG1216	Glycosyl transferase, family 2
BRPE64_RS16990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BRPE64_RS17000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRPE64_RS17010	COG1053	succinate dehydrogenase
BRPE64_RS17050	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS17070	COG0583	DNA-binding transcription factor activity
BRPE64_RS17075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BRPE64_RS17080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BRPE64_RS17090	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BRPE64_RS17095	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BRPE64_RS17100	COG1201	RNA secondary structure unwinding
BRPE64_RS17110	COG0515	serine threonine protein kinase
BRPE64_RS17110	COG2815	serine threonine protein kinase
BRPE64_RS17135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BRPE64_RS17180	COG3246	L-lysine catabolic process to acetate
BRPE64_RS17185	COG2186	Transcriptional regulator
BRPE64_RS17195	COG3842	ATPase activity
BRPE64_RS17235	COG0392	lysyltransferase activity
BRPE64_RS17235	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BRPE64_RS17260	COG2366	antibiotic biosynthetic process
BRPE64_RS17270	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BRPE64_RS17280	COG0251	oxidation-reduction process
BRPE64_RS17290	COG0730	response to heat
BRPE64_RS17305	COG0667	Aldo Keto reductase
BRPE64_RS17310	COG2207	Transcriptional regulator
BRPE64_RS17340	COG1959	2 iron, 2 sulfur cluster binding
BRPE64_RS17355	COG0709	Synthesizes selenophosphate from selenide and ATP
BRPE64_RS17365	COG0668	transmembrane transport
BRPE64_RS17385	COG0417	DNA replication proofreading
BRPE64_RS17400	COG2271	Major facilitator Superfamily
BRPE64_RS17410	COG2814	Major facilitator Superfamily
BRPE64_RS17425	COG1253	flavin adenine dinucleotide binding
BRPE64_RS17435	COG0025	NhaP-type Na H and K H
BRPE64_RS17445	COG3387	PFAM Glycoside hydrolase 15-related
BRPE64_RS17450	COG1461	Dihydroxyacetone kinase
BRPE64_RS17455	COG2376	Dihydroxyacetone kinase
BRPE64_RS17470	COG0583	DNA-binding transcription factor activity
BRPE64_RS17490	COG0477	Major facilitator Superfamily
BRPE64_RS17510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BRPE64_RS17525	COG4977	sequence-specific DNA binding
BRPE64_RS17565	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS17570	COG2084	Dehydrogenase
BRPE64_RS17575	COG0583	DNA-binding transcription factor activity
BRPE64_RS17595	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS17615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRPE64_RS17630	COG2207	Transcriptional regulator
BRPE64_RS17655	COG2271	Major facilitator Superfamily
BRPE64_RS17665	COG2351	hydroxyisourate hydrolase activity
BRPE64_RS17680	COG1764	response to oxidative stress
BRPE64_RS17695	COG5002	protein histidine kinase activity
BRPE64_RS17705	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BRPE64_RS17715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BRPE64_RS17720	COG0436	Aminotransferase
BRPE64_RS17740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BRPE64_RS17760	COG0450	alkyl hydroperoxide reductase
BRPE64_RS17765	COG0531	amino acid
BRPE64_RS17775	COG2192	nodulation
BRPE64_RS17795	COG3158	transport of potassium into the cell
BRPE64_RS17800	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BRPE64_RS17830	COG1595	DNA-templated transcription, initiation
BRPE64_RS17880	COG3604	Transcriptional regulator
BRPE64_RS17890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BRPE64_RS17895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRPE64_RS17900	COG1716	ATPase activity
BRPE64_RS17905	COG1538	Outer membrane efflux protein
BRPE64_RS17925	COG0515	serine threonine protein kinase
BRPE64_RS17925	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BRPE64_RS17970	COG0604	alcohol dehydrogenase
BRPE64_RS17975	COG0840	transmembrane signaling receptor activity
BRPE64_RS17985	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BRPE64_RS17990	COG1063	alcohol dehydrogenase
BRPE64_RS18005	COG3047	cAMP biosynthetic process
BRPE64_RS18035	COG0492	ferredoxin-NADP+ reductase activity
BRPE64_RS18045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BRPE64_RS18065	COG2863	cytochrome
BRPE64_RS18070	COG3604	Transcriptional regulator
BRPE64_RS18080	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BRPE64_RS18110	COG4608	Belongs to the ABC transporter superfamily
BRPE64_RS18120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRPE64_RS18125	COG0601	transmembrane transport
BRPE64_RS18145	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS18155	COG2252	PERMEase
BRPE64_RS18165	COG0640	Transcriptional regulator
BRPE64_RS18180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS18185	COG0387	Pfam Sodium calcium exchanger
BRPE64_RS18190	COG5001	Diguanylate cyclase
BRPE64_RS18190	COG3447	MASE1 domain protein
BRPE64_RS18190	COG5002	protein histidine kinase activity
BRPE64_RS18195	COG2271	Major facilitator Superfamily
BRPE64_RS18200	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS18215	COG1764	response to oxidative stress
BRPE64_RS18220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRPE64_RS18235	COG0859	PFAM glycosyl transferase family 9
BRPE64_RS18240	COG2321	neutral zinc metallopeptidase
BRPE64_RS18245	COG1271	oxidase subunit
BRPE64_RS18250	COG1294	oxidase, subunit
BRPE64_RS18255	COG0701	Predicted permease
BRPE64_RS18260	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BRPE64_RS18265	COG4303	Ethanolamine ammonia lyase large subunit
BRPE64_RS18270	COG4302	ethanolamine ammonia-lyase activity
BRPE64_RS18275	COG3284	Transcriptional regulator
BRPE64_RS18290	COG1253	flavin adenine dinucleotide binding
BRPE64_RS18370	COG1797	cobyrinic acid a,c-diamide synthase activity
BRPE64_RS18425	COG1538	Outer membrane efflux protein
BRPE64_RS18435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRPE64_RS18440	COG0657	acetylesterase activity
BRPE64_RS18445	COG0583	DNA-binding transcription factor activity
BRPE64_RS18460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BRPE64_RS18465	COG1763	Mo-molybdopterin cofactor biosynthetic process
BRPE64_RS18475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BRPE64_RS18480	COG1414	Transcriptional regulator
BRPE64_RS18505	COG4977	sequence-specific DNA binding
BRPE64_RS18520	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BRPE64_RS18525	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS18530	COG1522	sequence-specific DNA binding
BRPE64_RS18535	COG3608	succinylglutamate desuccinylase aspartoacylase
BRPE64_RS18540	COG0006	proline dipeptidase activity
BRPE64_RS18545	COG2423	ornithine cyclodeaminase activity
BRPE64_RS18550	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BRPE64_RS18555	COG1725	Transcriptional regulator
BRPE64_RS18560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS18565	COG0765	amino acid transport
BRPE64_RS18570	COG0765	amino acid transport
BRPE64_RS18575	COG1126	abc transporter atp-binding protein
BRPE64_RS18605	COG0784	Response regulator, receiver
BRPE64_RS18605	COG4191	Histidine kinase
BRPE64_RS18610	COG0004	ammonium transporteR
BRPE64_RS18625	COG1522	sequence-specific DNA binding
BRPE64_RS18640	COG0583	DNA-binding transcription factor activity
BRPE64_RS18650	COG1192	Involved in chromosome partitioning
BRPE64_RS18660	COG3842	ATPase activity
BRPE64_RS18665	COG0395	ABC-type sugar transport system, permease component
BRPE64_RS18670	COG1175	transmembrane transport
BRPE64_RS18675	COG1653	transport
BRPE64_RS18685	COG4948	Mandelate Racemase Muconate Lactonizing
BRPE64_RS18695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BRPE64_RS18720	COG0697	spore germination
BRPE64_RS18750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRPE64_RS18765	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BRPE64_RS18785	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BRPE64_RS18790	COG2085	NADP oxidoreductase coenzyme F420-dependent
BRPE64_RS18800	COG3634	alkyl hydroperoxide reductase activity
BRPE64_RS18805	COG2205	protein histidine kinase activity
BRPE64_RS18810	COG0583	DNA-binding transcription factor activity
BRPE64_RS18815	COG4106	trans-aconitate 2-methyltransferase activity
BRPE64_RS18850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRPE64_RS18855	COG0243	molybdopterin cofactor binding
BRPE64_RS18880	COG2733	membrane
BRPE64_RS18890	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BRPE64_RS18895	COG0596	Alpha beta hydrolase
BRPE64_RS18900	COG0473	3-isopropylmalate dehydrogenase activity
BRPE64_RS18915	COG0583	DNA-binding transcription factor activity
BRPE64_RS18940	COG4964	Belongs to the GSP D family
BRPE64_RS18995	COG2094	Belongs to the DNA glycosylase MPG family
BRPE64_RS19025	COG0174	glutamine synthetase
BRPE64_RS19035	COG0583	DNA-binding transcription factor activity
BRPE64_RS19040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BRPE64_RS19045	COG2814	Major facilitator Superfamily
BRPE64_RS19075	COG1045	serine acetyltransferase
BRPE64_RS19095	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BRPE64_RS19115	COG0477	Major facilitator Superfamily
BRPE64_RS19125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BRPE64_RS19130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BRPE64_RS19190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRPE64_RS19195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRPE64_RS19215	COG0346	lactoylglutathione lyase activity
BRPE64_RS19220	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BRPE64_RS19230	COG2188	Transcriptional regulator
BRPE64_RS19235	COG2081	HI0933 family
BRPE64_RS19250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BRPE64_RS19270	COG0129	dihydroxy-acid dehydratase activity
BRPE64_RS19275	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BRPE64_RS19300	COG0586	Pfam SNARE associated Golgi protein
BRPE64_RS19305	COG3276	selenocysteine insertion sequence binding
BRPE64_RS19320	COG2864	formate dehydrogenase
BRPE64_RS19325	COG0437	4 iron, 4 sulfur cluster binding
BRPE64_RS19340	COG1295	ribonuclease BN
BRPE64_RS19370	COG2308	Evidence 4 Homologs of previously reported genes of
BRPE64_RS19380	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS19385	COG0583	DNA-binding transcription factor activity
BRPE64_RS19405	COG0038	chloride channel
BRPE64_RS19410	COG0667	Aldo Keto reductase
BRPE64_RS19425	COG2203	Gaf domain
BRPE64_RS19425	COG5001	Diguanylate cyclase
BRPE64_RS19425	COG4251	negative regulation of phosphorylation
BRPE64_RS19425	COG3706	GGDEF domain
BRPE64_RS19445	COG0457	Tetratricopeptide repeat
BRPE64_RS19445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BRPE64_RS19455	COG0840	transmembrane signaling receptor activity
BRPE64_RS19475	COG0129	dihydroxy-acid dehydratase activity
BRPE64_RS19480	COG1609	Transcriptional regulator
BRPE64_RS19530	COG3511	phospholipase C
BRPE64_RS19540	COG1131	(ABC) transporter
BRPE64_RS19545	COG0842	Transport permease protein
BRPE64_RS19555	COG0318	PFAM AMP-dependent synthetase and ligase
BRPE64_RS19560	COG3386	PFAM SMP-30 Gluconolaconase
BRPE64_RS19565	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRPE64_RS19570	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS19575	COG1129	ABC transporter
BRPE64_RS19590	COG3246	L-lysine catabolic process to acetate
BRPE64_RS19595	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS19605	COG5002	protein histidine kinase activity
BRPE64_RS19610	COG2205	protein histidine kinase activity
BRPE64_RS19615	COG2172	sigma factor antagonist activity
BRPE64_RS19625	COG1366	Belongs to the anti-sigma-factor antagonist family
BRPE64_RS19630	COG1366	Belongs to the anti-sigma-factor antagonist family
BRPE64_RS19640	COG2233	PERMEase
BRPE64_RS19645	COG0739	heme binding
BRPE64_RS19700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BRPE64_RS19715	COG2081	HI0933 family
BRPE64_RS19720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BRPE64_RS19735	COG0583	DNA-binding transcription factor activity
BRPE64_RS19740	COG1469	GTP cyclohydrolase I activity
BRPE64_RS19745	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BRPE64_RS19750	COG0142	geranyltranstransferase activity
BRPE64_RS19770	COG0412	Dienelactone hydrolase
BRPE64_RS19775	COG1252	NADH dehydrogenase
BRPE64_RS19785	COG1611	Belongs to the LOG family
BRPE64_RS19795	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BRPE64_RS19805	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BRPE64_RS19815	COG1846	Transcriptional regulator
BRPE64_RS19820	COG1764	response to oxidative stress
BRPE64_RS19825	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BRPE64_RS19845	COG0306	phosphate transporter
BRPE64_RS19870	COG5642	Protein of unknown function (DUF2384)
BRPE64_RS19875	COG5654	RES domain protein
BRPE64_RS19885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BRPE64_RS19905	COG0297	glycogen (starch) synthase activity
BRPE64_RS19910	COG0366	Alpha amylase catalytic
BRPE64_RS19915	COG0366	Alpha amylase catalytic
BRPE64_RS19920	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BRPE64_RS19930	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BRPE64_RS19935	COG1640	4-alpha-glucanotransferase
BRPE64_RS19945	COG1253	flavin adenine dinucleotide binding
BRPE64_RS19955	COG1215	transferase activity, transferring glycosyl groups
BRPE64_RS19985	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS20035	COG0285	dihydrofolate synthase activity
BRPE64_RS20040	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BRPE64_RS20045	COG0159	tryptophan synthase activity
BRPE64_RS20055	COG0133	tryptophan synthase activity
BRPE64_RS20060	COG0135	phosphoribosylanthranilate isomerase activity
BRPE64_RS20065	COG0101	tRNA pseudouridine synthase activity
BRPE64_RS20080	COG0473	3-isopropylmalate dehydrogenase activity
BRPE64_RS20090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BRPE64_RS20105	COG0372	Belongs to the citrate synthase family
BRPE64_RS20110	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BRPE64_RS20115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BRPE64_RS20120	COG1053	succinate dehydrogenase
BRPE64_RS20125	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BRPE64_RS20130	COG2009	succinate dehydrogenase
BRPE64_RS20135	COG2188	Transcriptional regulator
BRPE64_RS20145	COG0039	L-malate dehydrogenase activity
BRPE64_RS20170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BRPE64_RS20180	COG0436	Aminotransferase
BRPE64_RS20210	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BRPE64_RS20215	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BRPE64_RS20230	COG0492	ferredoxin-NADP+ reductase activity
BRPE64_RS20240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRPE64_RS20245	COG3622	Belongs to the hyi family
BRPE64_RS20250	COG0235	Class ii aldolase
BRPE64_RS20255	COG3395	kinase activity
BRPE64_RS20260	COG2084	Dehydrogenase
BRPE64_RS20265	COG2186	Transcriptional regulator
BRPE64_RS20290	COG2059	Chromate
BRPE64_RS20295	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BRPE64_RS20305	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BRPE64_RS20320	COG0673	inositol 2-dehydrogenase activity
BRPE64_RS20330	COG1879	ABC-type sugar transport system periplasmic component
BRPE64_RS20335	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS20340	COG1129	ABC transporter
BRPE64_RS20345	COG1609	Transcriptional regulator
BRPE64_RS20350	COG3795	YCII-related domain
BRPE64_RS20355	COG0183	Belongs to the thiolase family
BRPE64_RS20375	COG0583	DNA-binding transcription factor activity
BRPE64_RS20380	COG0436	Aminotransferase
BRPE64_RS20385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS20430	COG0824	Thioesterase
BRPE64_RS20430	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRPE64_RS20435	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRPE64_RS20440	COG3246	L-lysine catabolic process to acetate
BRPE64_RS20455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BRPE64_RS20475	COG3119	arylsulfatase activity
BRPE64_RS20480	COG0583	DNA-binding transcription factor activity
BRPE64_RS20500	COG2113	Glycine betaine
BRPE64_RS20520	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BRPE64_RS20525	COG2181	nitrate reductase activity
BRPE64_RS20525	COG0247	lactate metabolic process
BRPE64_RS20530	COG0446	pyridine nucleotide-disulphide oxidoreductase
BRPE64_RS20530	COG1902	pentaerythritol trinitrate reductase activity
BRPE64_RS20565	COG1309	transcriptional regulator
BRPE64_RS20570	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS20575	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BRPE64_RS20580	COG0477	Major facilitator Superfamily
BRPE64_RS20600	COG0446	pyridine nucleotide-disulphide oxidoreductase
BRPE64_RS20600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BRPE64_RS20615	COG1760	l-serine dehydratase
BRPE64_RS20650	COG4175	Glycine betaine
BRPE64_RS20660	COG1285	pathogenesis
BRPE64_RS20670	COG0840	transmembrane signaling receptor activity
BRPE64_RS20680	COG0179	Fumarylacetoacetate (FAA) hydrolase
BRPE64_RS20685	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS20700	COG2721	sulfolactate sulfo-lyase activity
BRPE64_RS20710	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS20715	COG1129	ABC transporter
BRPE64_RS20745	COG1192	Involved in chromosome partitioning
BRPE64_RS20750	COG1475	DNA binding
BRPE64_RS20755	COG4206	TonB-dependent receptor
BRPE64_RS20785	COG0583	DNA-binding transcription factor activity
BRPE64_RS20820	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS20850	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS20875	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BRPE64_RS20890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BRPE64_RS20895	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BRPE64_RS20925	COG2271	Major facilitator Superfamily
BRPE64_RS20960	COG3842	ATPase activity
BRPE64_RS20975	COG4770	biotin carboxylase activity
BRPE64_RS20985	COG0475	glutathione-regulated potassium exporter activity
BRPE64_RS21005	COG3038	cytochrome b561
BRPE64_RS21010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRPE64_RS21025	COG1414	Transcriptional regulator
BRPE64_RS21040	COG1414	Transcriptional regulator
BRPE64_RS21045	COG1414	Transcriptional regulator
BRPE64_RS21065	COG1228	amidohydrolase
BRPE64_RS21070	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BRPE64_RS21090	COG1113	amino acid transport
BRPE64_RS21095	COG1414	Transcriptional regulator
BRPE64_RS21100	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS21105	COG0318	PFAM AMP-dependent synthetase and ligase
BRPE64_RS21110	COG2271	Major facilitator Superfamily
BRPE64_RS21145	COG0477	Major facilitator Superfamily
BRPE64_RS21160	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS21170	COG0028	Belongs to the TPP enzyme family
BRPE64_RS21175	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS21180	COG1414	Transcriptional regulator
BRPE64_RS21185	COG2226	methyltransferase
BRPE64_RS21185	COG1073	alpha beta
BRPE64_RS21220	COG1414	Transcriptional regulator
BRPE64_RS21245	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS21250	COG1280	lysine exporter protein (LysE YggA)
BRPE64_RS21275	COG0625	glutathione transferase activity
BRPE64_RS21285	COG2814	Major facilitator Superfamily
BRPE64_RS21295	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BRPE64_RS21305	COG1309	transcriptional regulator
BRPE64_RS21320	COG0300	oxidoreductase activity
BRPE64_RS21325	COG0583	DNA-binding transcription factor activity
BRPE64_RS21335	COG2814	Major facilitator Superfamily
BRPE64_RS21340	COG3608	succinylglutamate desuccinylase aspartoacylase
BRPE64_RS21345	COG0583	DNA-binding transcription factor activity
BRPE64_RS21350	COG0625	glutathione transferase activity
BRPE64_RS21385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BRPE64_RS21395	COG0542	response to heat
BRPE64_RS21405	COG2837	iron assimilation
BRPE64_RS21425	COG1278	Cold shock
BRPE64_RS21445	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BRPE64_RS21465	COG2226	methyltransferase
BRPE64_RS21470	COG4774	siderophore transport
BRPE64_RS21480	COG2175	clavaminate synthase activity
BRPE64_RS21485	COG1115	amino acid carrier protein
BRPE64_RS21500	COG2009	succinate dehydrogenase
BRPE64_RS21505	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BRPE64_RS21510	COG1053	succinate dehydrogenase
BRPE64_RS21515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BRPE64_RS21550	COG4608	Belongs to the ABC transporter superfamily
BRPE64_RS21560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRPE64_RS21565	COG0601	transmembrane transport
BRPE64_RS21570	COG0747	negative chemotaxis
BRPE64_RS21575	COG1335	isochorismatase
BRPE64_RS21585	COG0154	amidase activity
BRPE64_RS21590	COG0824	Thioesterase
BRPE64_RS21590	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRPE64_RS21595	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS21600	COG2271	Major facilitator Superfamily
BRPE64_RS21610	COG2271	Major facilitator Superfamily
BRPE64_RS21620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BRPE64_RS21630	COG0583	DNA-binding transcription factor activity
BRPE64_RS21645	COG0477	Major facilitator Superfamily
BRPE64_RS21650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRPE64_RS21660	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BRPE64_RS21665	COG1454	alcohol dehydrogenase
BRPE64_RS21670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BRPE64_RS21675	COG0583	DNA-binding transcription factor activity
BRPE64_RS21685	COG0477	Major facilitator Superfamily
BRPE64_RS21710	COG3618	amidohydrolase
BRPE64_RS21715	COG2271	Major facilitator Superfamily
BRPE64_RS21725	COG0545	Peptidyl-prolyl cis-trans isomerase
BRPE64_RS21735	COG0288	reversible hydration of carbon dioxide
BRPE64_RS21745	COG0583	DNA-binding transcription factor activity
BRPE64_RS21755	COG0038	chloride channel
BRPE64_RS21760	COG0281	malic enzyme
BRPE64_RS21775	COG2814	Major facilitator Superfamily
BRPE64_RS21780	COG0583	DNA-binding transcription factor activity
BRPE64_RS21825	COG0714	Associated with various cellular activities
BRPE64_RS21830	COG2916	Histone family protein nucleoid-structuring protein H-NS
BRPE64_RS21855	COG1137	ATPase activity
BRPE64_RS21880	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS21890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRPE64_RS21900	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS21910	COG1129	ABC transporter
BRPE64_RS21920	COG1051	belongs to the nudix hydrolase family
BRPE64_RS21935	COG1017	nitric oxide dioxygenase activity
BRPE64_RS21935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BRPE64_RS21945	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BRPE64_RS21955	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS21960	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS21970	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS21985	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS21990	COG0583	DNA-binding transcription factor activity
BRPE64_RS22005	COG1902	pentaerythritol trinitrate reductase activity
BRPE64_RS22010	COG1959	2 iron, 2 sulfur cluster binding
BRPE64_RS22015	COG0546	phosphoglycolate phosphatase activity
BRPE64_RS22025	COG3257	ureidoglycine aminohydrolase activity
BRPE64_RS22035	COG0596	Alpha beta hydrolase
BRPE64_RS22090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BRPE64_RS22095	COG0066	3-isopropylmalate dehydratase activity
BRPE64_RS22100	COG0473	3-isopropylmalate dehydrogenase activity
BRPE64_RS22105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BRPE64_RS22115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BRPE64_RS22120	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS22125	COG0179	Fumarylacetoacetate (FAA) hydrolase
BRPE64_RS22130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BRPE64_RS22150	COG1024	Enoyl-CoA hydratase
BRPE64_RS22160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BRPE64_RS22185	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS22190	COG2249	NAD(P)H dehydrogenase (quinone) activity
BRPE64_RS22195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BRPE64_RS22200	COG2814	Major facilitator Superfamily
BRPE64_RS22210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BRPE64_RS22220	COG0183	Belongs to the thiolase family
BRPE64_RS22235	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS22245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BRPE64_RS22250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BRPE64_RS22260	COG2814	Major facilitator Superfamily
BRPE64_RS22275	COG1879	ABC-type sugar transport system periplasmic component
BRPE64_RS22285	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS22290	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS22295	COG3386	PFAM SMP-30 Gluconolaconase
BRPE64_RS22300	COG1879	ABC-type sugar transport system periplasmic component
BRPE64_RS22320	COG0243	molybdopterin cofactor binding
BRPE64_RS22325	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS22330	COG0028	Belongs to the TPP enzyme family
BRPE64_RS22340	COG5002	protein histidine kinase activity
BRPE64_RS22350	COG0673	inositol 2-dehydrogenase activity
BRPE64_RS22355	COG0154	amidase activity
BRPE64_RS22375	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BRPE64_RS22390	COG1132	(ABC) transporter
BRPE64_RS22400	COG2259	Doxx family
BRPE64_RS22420	COG1069	ribulokinase activity
BRPE64_RS22430	COG4214	carbohydrate transport
BRPE64_RS22455	COG0583	DNA-binding transcription factor activity
BRPE64_RS22460	COG1301	dicarboxylic acid transport
BRPE64_RS22485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS22490	COG0765	amino acid transport
BRPE64_RS22495	COG0765	amino acid transport
BRPE64_RS22500	COG1126	abc transporter atp-binding protein
BRPE64_RS22515	COG2186	Transcriptional regulator
BRPE64_RS22520	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS22525	COG2271	Major facilitator Superfamily
BRPE64_RS22540	COG2721	sulfolactate sulfo-lyase activity
BRPE64_RS22545	COG2271	Major facilitator Superfamily
BRPE64_RS22550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRPE64_RS22560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BRPE64_RS22565	COG2271	Major facilitator Superfamily
BRPE64_RS22570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BRPE64_RS22575	COG0129	dihydroxy-acid dehydratase activity
BRPE64_RS22585	COG4948	Mandelate Racemase Muconate Lactonizing
BRPE64_RS22600	COG2828	Protein conserved in bacteria
BRPE64_RS22610	COG0745	RESPONSE REGULATOR receiver
BRPE64_RS22640	COG1216	Glycosyl transferase, family 2
BRPE64_RS22670	COG0656	L-ascorbic acid biosynthetic process
BRPE64_RS22680	COG0667	Aldo Keto reductase
BRPE64_RS22690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRPE64_RS22695	COG0477	Major facilitator Superfamily
BRPE64_RS22705	COG1309	transcriptional regulator
BRPE64_RS22740	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BRPE64_RS22745	COG0596	Alpha beta hydrolase
BRPE64_RS22750	COG0513	Belongs to the DEAD box helicase family
BRPE64_RS22760	COG3755	Protein conserved in bacteria
BRPE64_RS22770	COG0405	Gamma-glutamyltransferase
BRPE64_RS22775	COG0477	Major facilitator Superfamily
BRPE64_RS22785	COG2814	Major facilitator Superfamily
BRPE64_RS22795	COG3158	transport of potassium into the cell
BRPE64_RS22800	COG0583	DNA-binding transcription factor activity
BRPE64_RS22805	COG3959	Transketolase, thiamine diphosphate binding domain
BRPE64_RS22810	COG3958	Transketolase
BRPE64_RS22815	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS22820	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BRPE64_RS22835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BRPE64_RS22840	COG2084	Dehydrogenase
BRPE64_RS22955	COG1366	Belongs to the anti-sigma-factor antagonist family
BRPE64_RS22965	COG1366	Belongs to the anti-sigma-factor antagonist family
BRPE64_RS22975	COG2208	phosphoserine phosphatase activity
BRPE64_RS22975	COG2770	Histidine kinase
BRPE64_RS23015	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BRPE64_RS23025	COG2175	clavaminate synthase activity
BRPE64_RS23045	COG3246	L-lysine catabolic process to acetate
BRPE64_RS23080	COG0058	SHG alpha-glucan phosphorylase activity
BRPE64_RS23085	COG0517	IMP dehydrogenase activity
BRPE64_RS23090	COG0668	transmembrane transport
BRPE64_RS23110	COG1881	PFAM PEBP family protein
BRPE64_RS23120	COG1484	DNA-dependent DNA replication
BRPE64_RS23125	COG4584	PFAM Integrase catalytic
BRPE64_RS23145	COG0745	RESPONSE REGULATOR receiver
BRPE64_RS23170	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BRPE64_RS23175	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BRPE64_RS23180	COG4191	Histidine kinase
BRPE64_RS23190	COG0028	Belongs to the TPP enzyme family
BRPE64_RS23215	COG0745	RESPONSE REGULATOR receiver
BRPE64_RS23220	COG2205	protein histidine kinase activity
BRPE64_RS23225	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BRPE64_RS23230	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BRPE64_RS23235	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BRPE64_RS23245	COG1129	ABC transporter
BRPE64_RS23250	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS23275	COG2271	Major facilitator Superfamily
BRPE64_RS23280	COG4948	Mandelate Racemase Muconate Lactonizing
BRPE64_RS23290	COG2271	Major facilitator Superfamily
BRPE64_RS23310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRPE64_RS23335	COG0583	DNA-binding transcription factor activity
BRPE64_RS23340	COG1252	NADH dehydrogenase
BRPE64_RS23350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS23355	COG0765	amino acid transport
BRPE64_RS23360	COG1126	abc transporter atp-binding protein
BRPE64_RS23400	COG3842	ATPase activity
BRPE64_RS23430	COG0556	nucleotide-excision repair
BRPE64_RS23435	COG0741	lytic transglycosylase activity
BRPE64_RS23435	COG1196	nuclear chromosome segregation
BRPE64_RS23435	COG0739	heme binding
BRPE64_RS23440	COG0641	radical SAM
BRPE64_RS23445	COG3119	arylsulfatase activity
BRPE64_RS23475	COG2188	Transcriptional regulator
BRPE64_RS23480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BRPE64_RS23490	COG0114	fumarate hydratase activity
BRPE64_RS23510	COG1309	transcriptional regulator
BRPE64_RS23545	COG0583	DNA-binding transcription factor activity
BRPE64_RS23550	COG1335	isochorismatase
BRPE64_RS23555	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BRPE64_RS23585	COG4608	Belongs to the ABC transporter superfamily
BRPE64_RS23595	COG0747	negative chemotaxis
BRPE64_RS23600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRPE64_RS23605	COG0601	transmembrane transport
BRPE64_RS23620	COG1024	Enoyl-CoA hydratase
BRPE64_RS23630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BRPE64_RS23640	COG1522	sequence-specific DNA binding
BRPE64_RS23645	COG0473	3-isopropylmalate dehydrogenase activity
BRPE64_RS23650	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS23685	COG4172	Belongs to the ABC transporter superfamily
BRPE64_RS23690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRPE64_RS23695	COG0601	transmembrane transport
BRPE64_RS23705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRPE64_RS23715	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS23730	COG0446	pyridine nucleotide-disulphide oxidoreductase
BRPE64_RS23730	COG1902	pentaerythritol trinitrate reductase activity
BRPE64_RS23740	COG0583	DNA-binding transcription factor activity
BRPE64_RS23760	COG1177	transmembrane transport
BRPE64_RS23785	COG0251	oxidation-reduction process
BRPE64_RS23800	COG2271	Major facilitator Superfamily
BRPE64_RS23805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BRPE64_RS23825	COG0318	PFAM AMP-dependent synthetase and ligase
BRPE64_RS23830	COG1176	ABC-type spermidine putrescine transport system, permease component I
BRPE64_RS23835	COG3842	ATPase activity
BRPE64_RS23845	COG1024	Enoyl-CoA hydratase
BRPE64_RS23855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BRPE64_RS23875	COG2271	Major facilitator Superfamily
BRPE64_RS23885	COG3842	ATPase activity
BRPE64_RS23910	COG1283	sodium-dependent phosphate transmembrane transporter activity
BRPE64_RS23915	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BRPE64_RS23920	COG4191	Histidine kinase
BRPE64_RS23920	COG0784	Response regulator, receiver
BRPE64_RS23955	COG2814	Major facilitator Superfamily
BRPE64_RS23960	COG1566	PFAM secretion protein HlyD family protein
BRPE64_RS23970	COG1846	Transcriptional regulator
BRPE64_RS24015	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BRPE64_RS24020	COG0163	prenyltransferase activity
BRPE64_RS24025	COG0523	cobalamin synthesis protein
BRPE64_RS24030	COG2233	PERMEase
BRPE64_RS24050	COG0625	glutathione transferase activity
BRPE64_RS24065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BRPE64_RS24070	COG2203	Gaf domain
BRPE64_RS24070	COG3706	GGDEF domain
BRPE64_RS24070	COG4251	negative regulation of phosphorylation
BRPE64_RS24070	COG5001	Diguanylate cyclase
BRPE64_RS24085	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS24090	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS24095	COG1024	Enoyl-CoA hydratase
BRPE64_RS24095	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRPE64_RS24100	COG0583	DNA-binding transcription factor activity
BRPE64_RS24105	COG0697	spore germination
BRPE64_RS24110	COG0583	DNA-binding transcription factor activity
BRPE64_RS24125	COG4191	Histidine kinase
BRPE64_RS24125	COG0784	Response regulator, receiver
BRPE64_RS24130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BRPE64_RS24135	COG1802	Transcriptional regulator
BRPE64_RS24145	COG3842	ATPase activity
BRPE64_RS24155	COG1176	ABC-type spermidine putrescine transport system, permease component I
BRPE64_RS24160	COG3833	ABC-type maltose transport systems, permease component
BRPE64_RS24170	COG1079	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS24175	COG4603	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS24180	COG3845	ABC transporter
BRPE64_RS24195	COG0154	amidase activity
BRPE64_RS24220	COG0583	DNA-binding transcription factor activity
BRPE64_RS24240	COG1879	ABC-type sugar transport system periplasmic component
BRPE64_RS24250	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS24255	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS24260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRPE64_RS24270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BRPE64_RS24275	COG0596	Alpha beta hydrolase
BRPE64_RS24280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BRPE64_RS24285	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS24290	COG2271	Major facilitator Superfamily
BRPE64_RS24300	COG0583	DNA-binding transcription factor activity
BRPE64_RS24325	COG2814	Major facilitator Superfamily
BRPE64_RS24360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BRPE64_RS24395	COG1522	sequence-specific DNA binding
BRPE64_RS24440	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS24445	COG0596	Alpha beta hydrolase
BRPE64_RS24450	COG0583	DNA-binding transcription factor activity
BRPE64_RS24465	COG0596	Alpha beta hydrolase
BRPE64_RS24495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BRPE64_RS24515	COG2072	flavoprotein involved in K transport
BRPE64_RS24525	COG4638	Rieske (2fe-2S)
BRPE64_RS24530	COG3842	ATPase activity
BRPE64_RS24540	COG1176	ABC-type spermidine putrescine transport system, permease component I
BRPE64_RS24560	COG3123	guanosine phosphorylase activity
BRPE64_RS24575	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BRPE64_RS24580	COG1522	sequence-specific DNA binding
BRPE64_RS24585	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BRPE64_RS24600	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BRPE64_RS24600	COG0546	phosphoglycolate phosphatase activity
BRPE64_RS24635	COG0297	glycogen (starch) synthase activity
BRPE64_RS24635	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS24650	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS24655	COG0489	protein tyrosine kinase activity
BRPE64_RS24655	COG3206	protein involved in exopolysaccharide biosynthesis
BRPE64_RS24660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BRPE64_RS24665	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS24685	COG3511	phospholipase C
BRPE64_RS24690	COG1192	Involved in chromosome partitioning
BRPE64_RS24695	COG1475	DNA binding
BRPE64_RS24720	COG0840	transmembrane signaling receptor activity
BRPE64_RS24725	COG0625	glutathione transferase activity
BRPE64_RS24735	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS24745	COG3284	Transcriptional regulator
BRPE64_RS24750	COG3199	ATP-NAD kinase
BRPE64_RS24755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BRPE64_RS24760	COG0022	dehydrogenase e1 component
BRPE64_RS24765	COG0508	dehydrogenase complex catalyzes the overall conversion of
BRPE64_RS24765	COG0596	Alpha beta hydrolase
BRPE64_RS24770	COG0095	Lipoate-protein ligase
BRPE64_RS24795	COG0494	nUDIX hydrolase
BRPE64_RS24815	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BRPE64_RS24825	COG4804	nuclease activity
BRPE64_RS24865	COG0583	DNA-binding transcription factor activity
BRPE64_RS24870	COG0477	Major facilitator Superfamily
BRPE64_RS24875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BRPE64_RS24880	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BRPE64_RS24880	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BRPE64_RS24885	COG1609	Transcriptional regulator
BRPE64_RS24890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BRPE64_RS24900	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS24905	COG3706	GGDEF domain
BRPE64_RS24905	COG4251	negative regulation of phosphorylation
BRPE64_RS24905	COG2203	Gaf domain
BRPE64_RS24905	COG5001	Diguanylate cyclase
BRPE64_RS24910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BRPE64_RS24920	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BRPE64_RS24930	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BRPE64_RS24945	COG1595	DNA-templated transcription, initiation
BRPE64_RS24965	COG0277	FAD linked oxidase domain protein
BRPE64_RS24990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BRPE64_RS24995	COG0477	Major facilitator Superfamily
BRPE64_RS25000	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BRPE64_RS25025	COG4251	negative regulation of phosphorylation
BRPE64_RS25045	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BRPE64_RS25050	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS25055	COG2271	Major facilitator Superfamily
BRPE64_RS25060	COG4948	Mandelate Racemase Muconate Lactonizing
BRPE64_RS25080	COG0477	Major facilitator Superfamily
BRPE64_RS25090	COG0667	Aldo Keto reductase
BRPE64_RS25095	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
BRPE64_RS25105	COG0671	phosphoesterase, PA-phosphatase related
BRPE64_RS25115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BRPE64_RS25125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BRPE64_RS25135	COG0642	Histidine kinase
BRPE64_RS25145	COG1263	PTS System
BRPE64_RS25145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRPE64_RS25175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRPE64_RS25185	COG3938	Belongs to the proline racemase family
BRPE64_RS25190	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BRPE64_RS25195	COG1802	Transcriptional regulator
BRPE64_RS25220	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BRPE64_RS25245	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BRPE64_RS25250	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BRPE64_RS25265	COG2814	Major facilitator Superfamily
BRPE64_RS25285	COG0477	Major facilitator Superfamily
BRPE64_RS25290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BRPE64_RS25295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BRPE64_RS25305	COG0789	Transcriptional regulator
BRPE64_RS25310	COG1183	phosphatidylcholine synthase activity
BRPE64_RS25315	COG0583	DNA-binding transcription factor activity
BRPE64_RS25320	COG2814	Major facilitator Superfamily
BRPE64_RS25330	COG4566	intracellular signal transduction
BRPE64_RS25335	COG4191	Histidine kinase
BRPE64_RS25340	COG4566	intracellular signal transduction
BRPE64_RS25350	COG5001	Diguanylate cyclase
BRPE64_RS25355	COG0477	Major facilitator Superfamily
BRPE64_RS25365	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BRPE64_RS25420	COG1971	Probably functions as a manganese efflux pump
BRPE64_RS25430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BRPE64_RS25440	COG3546	catalase activity
BRPE64_RS25445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BRPE64_RS25450	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BRPE64_RS25455	COG3395	kinase activity
BRPE64_RS25465	COG1349	DNA-binding transcription factor activity
BRPE64_RS25470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS25470	COG0784	Response regulator, receiver
BRPE64_RS25470	COG2205	protein histidine kinase activity
BRPE64_RS25470	COG2198	Histidine kinase
BRPE64_RS25480	COG0583	DNA-binding transcription factor activity
BRPE64_RS25485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRPE64_RS25495	COG2188	Transcriptional regulator
BRPE64_RS25500	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BRPE64_RS25505	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BRPE64_RS25510	COG0235	Class ii aldolase
BRPE64_RS25515	COG1879	ABC-type sugar transport system periplasmic component
BRPE64_RS25520	COG1129	ABC transporter
BRPE64_RS25525	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS25530	COG2376	Dihydroxyacetone kinase
BRPE64_RS25535	COG1461	Dihydroxyacetone kinase
BRPE64_RS25550	COG3246	L-lysine catabolic process to acetate
BRPE64_RS25560	COG0747	negative chemotaxis
BRPE64_RS25580	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS25585	COG1024	Enoyl-CoA hydratase
BRPE64_RS25595	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS25610	COG0492	ferredoxin-NADP+ reductase activity
BRPE64_RS25645	COG3246	L-lysine catabolic process to acetate
BRPE64_RS25650	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS25690	COG2175	clavaminate synthase activity
BRPE64_RS25695	COG1120	ATPase activity
BRPE64_RS25730	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BRPE64_RS25735	COG4774	siderophore transport
BRPE64_RS25740	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BRPE64_RS25765	COG0235	Class ii aldolase
BRPE64_RS25770	COG1942	4-Oxalocrotonate Tautomerase
BRPE64_RS25775	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BRPE64_RS25785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BRPE64_RS25790	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BRPE64_RS25795	COG2080	2 iron, 2 sulfur cluster binding
BRPE64_RS25805	COG0583	DNA-binding transcription factor activity
BRPE64_RS25810	COG1473	amidohydrolase
BRPE64_RS25840	COG2223	nitrite transmembrane transporter activity
BRPE64_RS25845	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS25855	COG1024	Enoyl-CoA hydratase
BRPE64_RS25860	COG0318	PFAM AMP-dependent synthetase and ligase
BRPE64_RS25870	COG0625	glutathione transferase activity
BRPE64_RS25880	COG2249	NAD(P)H dehydrogenase (quinone) activity
BRPE64_RS25905	COG1129	ABC transporter
BRPE64_RS25925	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BRPE64_RS25930	COG2017	converts alpha-aldose to the beta-anomer
BRPE64_RS25940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BRPE64_RS25945	COG0784	Response regulator, receiver
BRPE64_RS25945	COG4191	Histidine kinase
BRPE64_RS25955	COG0477	Major facilitator Superfamily
BRPE64_RS25970	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS25975	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS25980	COG1129	ABC transporter
BRPE64_RS25985	COG1879	ABC-type sugar transport system periplasmic component
BRPE64_RS25990	COG1609	Transcriptional regulator
BRPE64_RS26025	COG1573	uracil-dna glycosylase
BRPE64_RS26030	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS26040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BRPE64_RS26050	COG0457	Tetratricopeptide repeat
BRPE64_RS26050	COG0859	PFAM glycosyl transferase family 9
BRPE64_RS26055	COG2814	Major facilitator Superfamily
BRPE64_RS26100	COG4964	Belongs to the GSP D family
BRPE64_RS26175	COG3842	ATPase activity
BRPE64_RS26180	COG1653	transport
BRPE64_RS26185	COG1175	transmembrane transport
BRPE64_RS26195	COG2390	Transcriptional regulator
BRPE64_RS26200	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS26205	COG1063	alcohol dehydrogenase
BRPE64_RS26235	COG0667	Aldo Keto reductase
BRPE64_RS26240	COG4638	Rieske (2fe-2S)
BRPE64_RS26255	COG2814	Major facilitator Superfamily
BRPE64_RS26275	COG2146	nitrite reductase [NAD(P)H] activity
BRPE64_RS26280	COG0523	cobalamin synthesis protein
BRPE64_RS26290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BRPE64_RS26305	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BRPE64_RS26310	COG1414	Transcriptional regulator
BRPE64_RS26315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BRPE64_RS26315	COG0543	2 iron, 2 sulfur cluster binding
BRPE64_RS26345	COG4638	Rieske (2fe-2S)
BRPE64_RS26360	COG0235	Class ii aldolase
BRPE64_RS26415	COG2916	Histone family protein nucleoid-structuring protein H-NS
BRPE64_RS26425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BRPE64_RS26440	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BRPE64_RS26440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRPE64_RS26450	COG2308	Evidence 4 Homologs of previously reported genes of
BRPE64_RS26480	COG0667	Aldo Keto reductase
BRPE64_RS26485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BRPE64_RS26500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BRPE64_RS26545	COG1802	Transcriptional regulator
BRPE64_RS26560	COG0247	lactate metabolic process
BRPE64_RS26560	COG0277	FAD linked oxidase domain protein
BRPE64_RS26565	COG2271	Major facilitator Superfamily
BRPE64_RS26570	COG1024	Enoyl-CoA hydratase
BRPE64_RS26575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BRPE64_RS26610	COG3284	Transcriptional regulator
BRPE64_RS26620	COG5001	Diguanylate cyclase
BRPE64_RS26620	COG4251	negative regulation of phosphorylation
BRPE64_RS26620	COG3706	GGDEF domain
BRPE64_RS26620	COG2203	Gaf domain
BRPE64_RS26635	COG0246	Mannitol dehydrogenase
BRPE64_RS26640	COG4948	Mandelate Racemase Muconate Lactonizing
BRPE64_RS26650	COG1063	alcohol dehydrogenase
BRPE64_RS26655	COG2271	Major facilitator Superfamily
BRPE64_RS26660	COG1802	Transcriptional regulator
BRPE64_RS26670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRPE64_RS26675	COG1136	(ABC) transporter
BRPE64_RS26685	COG1136	(ABC) transporter
BRPE64_RS26685	COG0577	efflux transmembrane transporter activity
BRPE64_RS26690	COG1942	4-Oxalocrotonate Tautomerase
BRPE64_RS26725	COG3119	arylsulfatase activity
BRPE64_RS26735	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BRPE64_RS26740	COG0714	Associated with various cellular activities
BRPE64_RS26760	COG2304	oxidoreductase activity
BRPE64_RS26785	COG2885	chlorophyll binding
BRPE64_RS26795	COG3958	Transketolase
BRPE64_RS26800	COG3959	Transketolase, thiamine diphosphate binding domain
BRPE64_RS26805	COG2271	Major facilitator Superfamily
BRPE64_RS26810	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS26815	COG0583	DNA-binding transcription factor activity
BRPE64_RS26825	COG2205	protein histidine kinase activity
BRPE64_RS26825	COG0784	Response regulator, receiver
BRPE64_RS26850	COG1595	DNA-templated transcription, initiation
BRPE64_RS26855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BRPE64_RS26865	COG0583	DNA-binding transcription factor activity
BRPE64_RS26870	COG1764	response to oxidative stress
BRPE64_RS26880	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS26890	COG1053	succinate dehydrogenase
BRPE64_RS26895	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS26905	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BRPE64_RS26915	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BRPE64_RS26920	COG1942	4-Oxalocrotonate Tautomerase
BRPE64_RS26925	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS26950	COG3618	amidohydrolase
BRPE64_RS26955	COG2814	Major facilitator Superfamily
BRPE64_RS26965	COG2267	carboxylic ester hydrolase activity
BRPE64_RS26985	COG2204	response regulator
BRPE64_RS26995	COG5001	Diguanylate cyclase
BRPE64_RS26995	COG2203	Gaf domain
BRPE64_RS26995	COG3706	GGDEF domain
BRPE64_RS26995	COG4251	negative regulation of phosphorylation
BRPE64_RS27000	COG2205	protein histidine kinase activity
BRPE64_RS27000	COG0784	Response regulator, receiver
BRPE64_RS27000	COG5002	protein histidine kinase activity
BRPE64_RS27005	COG0596	Alpha beta hydrolase
BRPE64_RS27025	COG0730	response to heat
BRPE64_RS27035	COG1278	Cold shock
BRPE64_RS27040	COG0235	Class ii aldolase
BRPE64_RS27045	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS27050	COG1129	ABC transporter
BRPE64_RS27055	COG1879	ABC-type sugar transport system periplasmic component
BRPE64_RS27080	COG0702	epimerase
BRPE64_RS27090	COG1215	transferase activity, transferring glycosyl groups
BRPE64_RS27110	COG0840	transmembrane signaling receptor activity
BRPE64_RS27120	COG2271	Major facilitator Superfamily
BRPE64_RS27125	COG1609	Transcriptional regulator
BRPE64_RS27130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRPE64_RS27145	COG2186	Transcriptional regulator
BRPE64_RS27150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRPE64_RS27155	COG0765	amino acid transport
BRPE64_RS27160	COG0765	amino acid transport
BRPE64_RS27170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS27175	COG0028	Belongs to the TPP enzyme family
BRPE64_RS27185	COG0640	Transcriptional regulator
BRPE64_RS27225	COG0785	Cytochrome C biogenesis protein
BRPE64_RS27225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRPE64_RS27240	COG4948	Mandelate Racemase Muconate Lactonizing
BRPE64_RS27260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BRPE64_RS27265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BRPE64_RS27270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BRPE64_RS27275	COG1116	anion transmembrane transporter activity
BRPE64_RS27305	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BRPE64_RS27310	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS27320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRPE64_RS27325	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS27335	COG1129	ABC transporter
BRPE64_RS27345	COG1349	DNA-binding transcription factor activity
BRPE64_RS27395	COG0697	spore germination
BRPE64_RS27405	COG0446	pyridine nucleotide-disulphide oxidoreductase
BRPE64_RS27440	COG3473	Maleate cis-trans isomerase
BRPE64_RS27445	COG0596	Alpha beta hydrolase
BRPE64_RS27450	COG2309	aminopeptidase activity
BRPE64_RS27455	COG1335	isochorismatase
BRPE64_RS27460	COG0477	Major facilitator Superfamily
BRPE64_RS27475	COG3135	benzoate transporter
BRPE64_RS27505	COG0583	DNA-binding transcription factor activity
BRPE64_RS27510	COG0477	Major facilitator Superfamily
BRPE64_RS27525	COG1560	Kdo2-lipid A biosynthetic process
BRPE64_RS27545	COG4191	Histidine kinase
BRPE64_RS27550	COG4566	intracellular signal transduction
BRPE64_RS27555	COG4566	intracellular signal transduction
BRPE64_RS27560	COG2801	Transposase and inactivated derivatives
BRPE64_RS27595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BRPE64_RS27600	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS27610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BRPE64_RS27630	COG2986	histidine ammonia-lyase
BRPE64_RS27650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BRPE64_RS27695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRPE64_RS27735	COG2205	protein histidine kinase activity
BRPE64_RS27745	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BRPE64_RS27745	COG1672	PFAM Archaeal ATPase
BRPE64_RS27770	COG2175	clavaminate synthase activity
BRPE64_RS27785	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BRPE64_RS27805	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS27810	COG0183	Belongs to the thiolase family
BRPE64_RS27815	COG2030	dehydratase
BRPE64_RS27825	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS27835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BRPE64_RS27845	COG0318	PFAM AMP-dependent synthetase and ligase
BRPE64_RS27850	COG1024	Enoyl-CoA hydratase
BRPE64_RS27860	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS27865	COG0318	PFAM AMP-dependent synthetase and ligase
BRPE64_RS27870	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS27875	COG0183	Belongs to the thiolase family
BRPE64_RS27880	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS27890	COG3038	cytochrome b561
BRPE64_RS27900	COG2249	NAD(P)H dehydrogenase (quinone) activity
BRPE64_RS27905	COG1024	Enoyl-CoA hydratase
BRPE64_RS27925	COG2271	Major facilitator Superfamily
BRPE64_RS27930	COG0235	Class ii aldolase
BRPE64_RS27960	COG3842	ATPase activity
BRPE64_RS27965	COG1176	ABC-type spermidine putrescine transport system, permease component I
BRPE64_RS27985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRPE64_RS28050	COG0583	DNA-binding transcription factor activity
BRPE64_RS28060	COG1686	Belongs to the peptidase S11 family
BRPE64_RS28080	COG1764	response to oxidative stress
BRPE64_RS28095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRPE64_RS28120	COG0204	Acyl-transferase
BRPE64_RS28120	COG0318	PFAM AMP-dependent synthetase and ligase
BRPE64_RS28135	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS28180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BRPE64_RS28195	COG2226	methyltransferase
BRPE64_RS28205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BRPE64_RS28210	COG1695	Transcriptional regulator
BRPE64_RS28215	COG2375	cellular response to nickel ion
BRPE64_RS28225	COG0066	3-isopropylmalate dehydratase activity
BRPE64_RS28230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BRPE64_RS28245	COG1116	anion transmembrane transporter activity
BRPE64_RS28270	COG0583	DNA-binding transcription factor activity
BRPE64_RS28275	COG4122	O-methyltransferase activity
BRPE64_RS28295	COG0659	secondary active sulfate transmembrane transporter activity
BRPE64_RS28300	COG0288	reversible hydration of carbon dioxide
BRPE64_RS28315	COG0726	polysaccharide deacetylase
BRPE64_RS28345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BRPE64_RS28355	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BRPE64_RS28400	COG0583	DNA-binding transcription factor activity
BRPE64_RS28410	COG0583	DNA-binding transcription factor activity
BRPE64_RS28450	COG3618	amidohydrolase
BRPE64_RS28455	COG3618	amidohydrolase
BRPE64_RS28470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BRPE64_RS28475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BRPE64_RS28480	COG1024	Enoyl-CoA hydratase
BRPE64_RS28485	COG1454	alcohol dehydrogenase
BRPE64_RS28500	COG0583	DNA-binding transcription factor activity
BRPE64_RS28510	COG0477	Major facilitator Superfamily
BRPE64_RS28520	COG1301	dicarboxylic acid transport
BRPE64_RS28550	COG0583	DNA-binding transcription factor activity
BRPE64_RS28555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BRPE64_RS28595	COG1566	PFAM secretion protein HlyD family protein
BRPE64_RS28605	COG2186	Transcriptional regulator
BRPE64_RS28610	COG0277	FAD linked oxidase domain protein
BRPE64_RS28615	COG0277	FAD linked oxidase domain protein
BRPE64_RS28620	COG0247	lactate metabolic process
BRPE64_RS28630	COG1566	PFAM secretion protein HlyD family protein
BRPE64_RS28655	COG2814	Major facilitator Superfamily
BRPE64_RS28660	COG4829	muconolactone delta-isomerase
BRPE64_RS28665	COG4948	Mandelate Racemase Muconate Lactonizing
BRPE64_RS28670	COG0583	DNA-binding transcription factor activity
BRPE64_RS28695	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS28705	COG0583	DNA-binding transcription factor activity
BRPE64_RS28710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BRPE64_RS28730	COG3920	Histidine kinase
BRPE64_RS28745	COG3706	GGDEF domain
BRPE64_RS28785	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BRPE64_RS28805	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS28820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BRPE64_RS28825	COG0243	molybdopterin cofactor binding
BRPE64_RS28830	COG1271	oxidase subunit
BRPE64_RS28835	COG1294	oxidase, subunit
BRPE64_RS28855	COG0656	L-ascorbic acid biosynthetic process
BRPE64_RS28860	COG0596	Alpha beta hydrolase
BRPE64_RS28870	COG4191	Histidine kinase
BRPE64_RS28885	COG4566	intracellular signal transduction
BRPE64_RS28905	COG0028	Belongs to the TPP enzyme family
BRPE64_RS28920	COG0583	DNA-binding transcription factor activity
BRPE64_RS28960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRPE64_RS28990	COG0662	Cupin 2, conserved barrel domain protein
BRPE64_RS29030	COG1850	ribulose-bisphosphate carboxylase activity
BRPE64_RS29070	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS29075	COG4689	acetoacetate decarboxylase
BRPE64_RS29090	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS29125	COG1960	acyl-CoA dehydrogenase activity
BRPE64_RS29130	COG0318	PFAM AMP-dependent synthetase and ligase
BRPE64_RS29135	COG1024	Enoyl-CoA hydratase
BRPE64_RS29155	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BRPE64_RS29160	COG1309	transcriptional regulator
BRPE64_RS29185	COG0604	alcohol dehydrogenase
BRPE64_RS29185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BRPE64_RS29185	COG3321	synthase
BRPE64_RS29185	COG4221	oxidoreductase activity
BRPE64_RS29200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BRPE64_RS29205	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BRPE64_RS29210	COG1595	DNA-templated transcription, initiation
BRPE64_RS29215	COG4944	Protein of unknown function (DUF1109)
BRPE64_RS29225	COG0625	glutathione transferase activity
BRPE64_RS29230	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BRPE64_RS29240	COG2721	sulfolactate sulfo-lyase activity
BRPE64_RS29245	COG2721	sulfolactate sulfo-lyase activity
BRPE64_RS29250	COG2188	Transcriptional regulator
BRPE64_RS29285	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS29290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BRPE64_RS29295	COG3162	membrane
BRPE64_RS29310	COG1538	Outer membrane efflux protein
BRPE64_RS29315	COG2995	paraquat-inducible protein a
BRPE64_RS29320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BRPE64_RS29320	COG3008	intermembrane lipid transfer
BRPE64_RS29330	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BRPE64_RS29365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BRPE64_RS29390	COG4221	oxidoreductase activity
BRPE64_RS29395	COG0477	Major facilitator Superfamily
BRPE64_RS29405	COG0668	transmembrane transport
BRPE64_RS29410	COG0469	pyruvate kinase activity
BRPE64_RS29415	COG0583	DNA-binding transcription factor activity
BRPE64_RS29420	COG0583	DNA-binding transcription factor activity
BRPE64_RS29445	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS29455	COG0583	DNA-binding transcription factor activity
BRPE64_RS29460	COG2721	sulfolactate sulfo-lyase activity
BRPE64_RS29470	COG2271	Major facilitator Superfamily
BRPE64_RS29490	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BRPE64_RS29510	COG5434	Belongs to the glycosyl hydrolase 28 family
BRPE64_RS29525	COG0596	Alpha beta hydrolase
BRPE64_RS29535	COG2271	Major facilitator Superfamily
BRPE64_RS29570	COG5001	Diguanylate cyclase
BRPE64_RS29570	COG3300	MHYT domain
BRPE64_RS29595	COG0583	DNA-binding transcription factor activity
BRPE64_RS29600	COG1902	pentaerythritol trinitrate reductase activity
BRPE64_RS29620	COG2159	amidohydrolase
BRPE64_RS29630	COG3384	dioxygenase
BRPE64_RS29645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BRPE64_RS29650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BRPE64_RS29665	COG2070	2-Nitropropane dioxygenase
BRPE64_RS29680	COG0583	DNA-binding transcription factor activity
BRPE64_RS29695	COG3588	fructose-bisphosphate aldolase
BRPE64_RS29715	COG0583	DNA-binding transcription factor activity
BRPE64_RS29720	COG1562	ergosterol biosynthetic process
BRPE64_RS29730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BRPE64_RS29735	COG2755	lipolytic protein G-D-S-L family
BRPE64_RS29735	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BRPE64_RS29755	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BRPE64_RS29760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRPE64_RS29765	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS29770	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS29790	COG3206	protein involved in exopolysaccharide biosynthesis
BRPE64_RS29790	COG0489	protein tyrosine kinase activity
BRPE64_RS29810	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BRPE64_RS29825	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BRPE64_RS29825	COG2755	lipolytic protein G-D-S-L family
BRPE64_RS29835	COG1846	Transcriptional regulator
BRPE64_RS29840	COG1846	Transcriptional regulator
BRPE64_RS29845	COG2010	Cytochrome c
BRPE64_RS29845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BRPE64_RS29850	COG2080	2 iron, 2 sulfur cluster binding
BRPE64_RS29855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BRPE64_RS29860	COG3473	Maleate cis-trans isomerase
BRPE64_RS29865	COG0596	Alpha beta hydrolase
BRPE64_RS29870	COG2309	aminopeptidase activity
BRPE64_RS29875	COG1335	isochorismatase
BRPE64_RS29880	COG2271	Major facilitator Superfamily
BRPE64_RS29885	COG2010	Cytochrome c
BRPE64_RS29885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BRPE64_RS29910	COG2816	NAD+ diphosphatase activity
BRPE64_RS29920	COG1609	Transcriptional regulator
BRPE64_RS29925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BRPE64_RS29945	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BRPE64_RS29955	COG2197	response regulator
BRPE64_RS29960	COG1309	transcriptional regulator
BRPE64_RS29965	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BRPE64_RS29965	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BRPE64_RS29985	COG0438	transferase activity, transferring glycosyl groups
BRPE64_RS29990	COG2144	transferase activity, transferring acyl groups
BRPE64_RS30020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRPE64_RS30035	COG1215	transferase activity, transferring glycosyl groups
BRPE64_RS30045	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BRPE64_RS30055	COG0431	NADPH-dependent FMN reductase
BRPE64_RS30070	COG0798	PFAM Bile acid sodium symporter
BRPE64_RS30090	COG2814	Major facilitator Superfamily
BRPE64_RS30125	COG2851	Citrate transporter
BRPE64_RS30130	COG0583	DNA-binding transcription factor activity
BRPE64_RS30135	COG1064	alcohol dehydrogenase
BRPE64_RS30145	COG1403	HNH endonuclease
BRPE64_RS30170	COG0243	molybdopterin cofactor binding
BRPE64_RS30175	COG3043	anaerobic respiration
BRPE64_RS30180	COG3005	denitrification pathway
BRPE64_RS30185	COG4133	protoheme IX ABC transporter activity
BRPE64_RS30200	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BRPE64_RS30210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRPE64_RS30215	COG3088	subunit of a heme lyase
BRPE64_RS30230	COG2070	2-Nitropropane dioxygenase
BRPE64_RS30235	COG2197	response regulator
BRPE64_RS30240	COG4585	Histidine kinase
BRPE64_RS30245	COG3842	ATPase activity
BRPE64_RS30280	COG1414	Transcriptional regulator
BRPE64_RS30300	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BRPE64_RS30315	COG2271	Major facilitator Superfamily
BRPE64_RS30320	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS30325	COG1414	Transcriptional regulator
BRPE64_RS30360	COG1414	Transcriptional regulator
BRPE64_RS30370	COG1879	ABC-type sugar transport system periplasmic component
BRPE64_RS30380	COG1956	GAF domain-containing protein
BRPE64_RS30385	COG1940	carbohydrate kinase activity
BRPE64_RS30395	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRPE64_RS30400	COG1879	ABC-type sugar transport system periplasmic component
BRPE64_RS30430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BRPE64_RS30435	COG0784	Response regulator, receiver
BRPE64_RS30435	COG2205	protein histidine kinase activity
BRPE64_RS30455	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS30460	COG0183	Belongs to the thiolase family
BRPE64_RS30475	COG1914	H( )-stimulated, divalent metal cation uptake system
BRPE64_RS30490	COG1192	Involved in chromosome partitioning
BRPE64_RS30495	COG1475	DNA binding
BRPE64_RS30525	COG0410	ABC transporter
BRPE64_RS30530	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS30535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BRPE64_RS30545	COG0508	dehydrogenase complex catalyzes the overall conversion of
BRPE64_RS30550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BRPE64_RS30560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BRPE64_RS30565	COG2814	Major facilitator Superfamily
BRPE64_RS30585	COG4977	sequence-specific DNA binding
BRPE64_RS30610	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BRPE64_RS30625	COG0583	DNA-binding transcription factor activity
BRPE64_RS30650	COG4191	Histidine kinase
BRPE64_RS30655	COG4566	intracellular signal transduction
BRPE64_RS30660	COG4566	intracellular signal transduction
BRPE64_RS30680	COG0667	Aldo Keto reductase
BRPE64_RS30705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRPE64_RS30720	COG0183	Belongs to the thiolase family
BRPE64_RS30725	COG0492	ferredoxin-NADP+ reductase activity
BRPE64_RS30735	COG1309	transcriptional regulator
BRPE64_RS30745	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS30775	COG2223	nitrite transmembrane transporter activity
BRPE64_RS30780	COG0604	alcohol dehydrogenase
BRPE64_RS30805	COG0154	amidase activity
BRPE64_RS30825	COG2271	Major facilitator Superfamily
BRPE64_RS30850	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS30855	COG1902	pentaerythritol trinitrate reductase activity
BRPE64_RS30860	COG0583	DNA-binding transcription factor activity
BRPE64_RS30865	COG1126	abc transporter atp-binding protein
BRPE64_RS30870	COG0765	amino acid transport
BRPE64_RS30875	COG0765	amino acid transport
BRPE64_RS30880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS30885	COG3842	ATPase activity
BRPE64_RS30895	COG1176	ABC-type spermidine putrescine transport system, permease component I
BRPE64_RS30905	COG1012	belongs to the aldehyde dehydrogenase family
BRPE64_RS30915	COG1335	isochorismatase
BRPE64_RS30920	COG0477	Major facilitator Superfamily
BRPE64_RS30925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BRPE64_RS30940	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS30945	COG0583	DNA-binding transcription factor activity
BRPE64_RS30955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS30960	COG0765	amino acid transport
BRPE64_RS30980	COG0488	(ABC) transporter
BRPE64_RS31005	COG2124	cytochrome p450
BRPE64_RS31035	COG0657	acetylesterase activity
BRPE64_RS31040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRPE64_RS31065	COG0583	DNA-binding transcription factor activity
BRPE64_RS31085	COG0583	DNA-binding transcription factor activity
BRPE64_RS31095	COG0519	Catalyzes the synthesis of GMP from XMP
BRPE64_RS31095	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BRPE64_RS31100	COG0523	cobalamin synthesis protein
BRPE64_RS31135	COG0662	Cupin 2, conserved barrel domain protein
BRPE64_RS31135	COG2207	Transcriptional regulator
BRPE64_RS31140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS31150	COG4160	amino acid transport
BRPE64_RS31155	COG4215	(ABC) transporter
BRPE64_RS31165	COG1414	Transcriptional regulator
BRPE64_RS31170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BRPE64_RS31175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS31205	COG1215	transferase activity, transferring glycosyl groups
BRPE64_RS31240	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BRPE64_RS31245	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BRPE64_RS31275	COG0156	8-amino-7-oxononanoate synthase activity
BRPE64_RS31280	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BRPE64_RS31285	COG3321	synthase
BRPE64_RS31285	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS31285	COG0604	alcohol dehydrogenase
BRPE64_RS31290	COG1368	sulfuric ester hydrolase activity
BRPE64_RS31340	COG2916	Histone family protein nucleoid-structuring protein H-NS
BRPE64_RS31345	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS31350	COG0583	DNA-binding transcription factor activity
BRPE64_RS31405	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BRPE64_RS31415	COG2814	Major facilitator Superfamily
BRPE64_RS31420	COG0583	DNA-binding transcription factor activity
BRPE64_RS31425	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BRPE64_RS31460	COG0596	Alpha beta hydrolase
BRPE64_RS31470	COG0583	DNA-binding transcription factor activity
BRPE64_RS31475	COG0583	DNA-binding transcription factor activity
BRPE64_RS31480	COG1028	Short-chain dehydrogenase reductase Sdr
BRPE64_RS31495	COG0765	amino acid transport
BRPE64_RS31500	COG0765	amino acid transport
BRPE64_RS31505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRPE64_RS31510	COG1126	abc transporter atp-binding protein
BRPE64_RS31520	COG0583	DNA-binding transcription factor activity
BRPE64_RS31525	COG0477	Major facilitator Superfamily
BRPE64_RS31525	COG2814	Major facilitator Superfamily
BRPE64_RS31535	COG3618	amidohydrolase
BRPE64_RS31540	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BRPE64_RS31545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BRPE64_RS31570	COG0583	DNA-binding transcription factor activity
BRPE64_RS31575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BRPE64_RS31610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BRPE64_RS31615	COG0235	Class ii aldolase
BRPE64_RS31630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRPE64_RS31640	COG0625	glutathione transferase activity
BRPE64_RS31645	COG1309	transcriptional regulator
BRPE64_RS31650	COG4221	oxidoreductase activity
BRPE64_RS31655	COG0778	Nitroreductase
BRPE64_RS31675	COG2814	Major facilitator Superfamily
BRPE64_RS31705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BRPE64_RS31710	COG0183	Belongs to the thiolase family
BRPE64_RS31755	COG2031	fatty acid transporter
BRPE64_RS31770	COG0417	DNA replication proofreading
BRPE64_RS31775	COG0583	DNA-binding transcription factor activity
BRPE64_RS31780	COG0519	Catalyzes the synthesis of GMP from XMP
BRPE64_RS31840	COG1045	serine acetyltransferase
BRPE64_RS31980	COG1923	regulation of RNA biosynthetic process
BRPE64_RS32040	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BRPE64_RS32060	COG1649	PFAM Uncharacterised BCR, COG1649
BRPE64_RS32060	COG0726	polysaccharide deacetylase
BRPE64_RS32100	COG1187	pseudouridine synthase activity
BRPE64_RS32130	COG5487	UPF0391 membrane protein
BRPE64_RS32165	COG0154	amidase activity
BRPE64_RS32175	COG2921	Belongs to the UPF0250 family
BRPE64_RS32180	COG2226	methyltransferase
BRPE64_RS32320	COG0352	thiamine-phosphate diphosphorylase activity
BRPE64_RS32325	COG0489	protein tyrosine kinase activity
BRPE64_RS32325	COG3206	protein involved in exopolysaccharide biosynthesis
BRPE64_RS32330	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BRPE64_RS32410	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BRPE64_RS32435	COG0789	Transcriptional regulator
BRPE64_RS32595	COG3813	Protein conserved in bacteria
BRPE64_RS32630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)