locus-tag	class	description
BM45_RS00005	COG0067	glutamate synthase
BM45_RS00005	COG0070	glutamate synthase
BM45_RS00005	COG0069	glutamate synthase activity
BM45_RS00015	COG1115	amino acid carrier protein
BM45_RS00025	COG4178	(ABC) transporter
BM45_RS00050	COG1127	ABC transporter
BM45_RS00055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BM45_RS00060	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BM45_RS00080	COG1131	(ABC) transporter
BM45_RS00085	COG0842	Transport permease protein
BM45_RS00095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BM45_RS00105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BM45_RS00110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BM45_RS00120	COG2095	MarC family integral membrane protein
BM45_RS00165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BM45_RS00170	COG0805	protein transport
BM45_RS00180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BM45_RS00185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BM45_RS00190	COG0723	plastoquinol--plastocyanin reductase activity
BM45_RS00195	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BM45_RS00200	COG2857	Cytochrome c1
BM45_RS00205	COG0625	glutathione transferase activity
BM45_RS00210	COG2969	positive regulation of protein catabolic process
BM45_RS00225	COG4695	Portal protein
BM45_RS00230	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BM45_RS00235	COG3657	addiction module killer protein
BM45_RS00265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BM45_RS00270	COG1024	Enoyl-CoA hydratase
BM45_RS00270	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM45_RS00275	COG0183	Belongs to the thiolase family
BM45_RS00280	COG1960	acyl-CoA dehydrogenase activity
BM45_RS00305	COG1695	Transcriptional regulator
BM45_RS00365	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS00385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS00400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BM45_RS00410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BM45_RS00420	COG4106	trans-aconitate 2-methyltransferase activity
BM45_RS00420	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BM45_RS00425	COG0789	Transcriptional regulator
BM45_RS00435	COG1987	bacterial-type flagellum assembly
BM45_RS00445	COG2801	Transposase and inactivated derivatives
BM45_RS00465	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BM45_RS00485	COG1346	cytolysis
BM45_RS00495	COG0583	DNA-binding transcription factor activity
BM45_RS00505	COG1846	Transcriptional regulator
BM45_RS00550	COG2165	general secretion pathway protein
BM45_RS00565	COG1459	type II secretion system
BM45_RS00585	COG0523	cobalamin synthesis protein
BM45_RS00610	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BM45_RS00615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BM45_RS00620	COG2801	Transposase and inactivated derivatives
BM45_RS00625	COG2963	transposase activity
BM45_RS00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BM45_RS00700	COG0514	ATP-dependent DNA helicase (RecQ)
BM45_RS00830	COG0201	protein transport
BM45_RS00875	COG4232	protein-disulfide reductase activity
BM45_RS00895	COG1333	cytochrome c biogenesis protein
BM45_RS00900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BM45_RS00905	COG2963	transposase activity
BM45_RS00910	COG2801	Transposase and inactivated derivatives
BM45_RS00920	COG3047	cAMP biosynthetic process
BM45_RS00935	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BM45_RS00945	COG1881	PFAM PEBP family protein
BM45_RS00950	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BM45_RS00955	COG0281	malic enzyme
BM45_RS00955	COG0280	phosphate acetyltransferase
BM45_RS00980	COG1522	sequence-specific DNA binding
BM45_RS01000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BM45_RS01005	COG2151	metal-sulfur cluster biosynthetic enzyme
BM45_RS01010	COG3396	Phenylacetate-CoA oxygenase
BM45_RS01015	COG3460	Phenylacetate-CoA oxygenase
BM45_RS01055	COG2963	transposase activity
BM45_RS01060	COG2801	Transposase and inactivated derivatives
BM45_RS01085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BM45_RS01090	COG4221	oxidoreductase activity
BM45_RS01095	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS01105	COG0747	negative chemotaxis
BM45_RS01110	COG0488	(ABC) transporter
BM45_RS01125	COG0288	reversible hydration of carbon dioxide
BM45_RS01130	COG0183	Belongs to the thiolase family
BM45_RS01140	COG3012	SEC-C Motif Domain Protein
BM45_RS01185	COG1785	Belongs to the alkaline phosphatase family
BM45_RS01200	COG2801	Transposase and inactivated derivatives
BM45_RS01205	COG2963	transposase activity
BM45_RS01210	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS01225	COG0840	transmembrane signaling receptor activity
BM45_RS01230	COG1609	Transcriptional regulator
BM45_RS01280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BM45_RS01295	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM45_RS01300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM45_RS01320	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BM45_RS01325	COG1704	LemA family
BM45_RS01400	COG2801	Transposase and inactivated derivatives
BM45_RS01425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS01435	COG2824	Alkylphosphonate utilization operon protein PhnA
BM45_RS01455	COG0583	DNA-binding transcription factor activity
BM45_RS01460	COG2233	PERMEase
BM45_RS01465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BM45_RS01475	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BM45_RS01485	COG1706	bacterial-type flagellum-dependent cell motility
BM45_RS01490	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BM45_RS01505	COG1749	Flagellar hook protein flgE
BM45_RS01510	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BM45_RS01515	COG1558	bacterial-type flagellum-dependent cell motility
BM45_RS01520	COG1815	bacterial-type flagellum-dependent cell motility
BM45_RS01535	COG2747	anti-sigma28 factor FlgM
BM45_RS01565	COG0741	lytic transglycosylase activity
BM45_RS01570	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BM45_RS01585	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BM45_RS01590	COG1984	allophanate hydrolase subunit 2
BM45_RS01620	COG4608	Belongs to the ABC transporter superfamily
BM45_RS01625	COG0444	Belongs to the ABC transporter superfamily
BM45_RS01635	COG0601	transmembrane transport
BM45_RS01640	COG0747	negative chemotaxis
BM45_RS01655	COG0579	oxidoreductase
BM45_RS01675	COG3568	Endonuclease Exonuclease Phosphatase
BM45_RS01680	COG1280	lysine exporter protein (LysE YggA)
BM45_RS01705	COG0531	amino acid
BM45_RS01720	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BM45_RS01795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BM45_RS01805	COG2814	Major facilitator Superfamily
BM45_RS01820	COG0667	Aldo Keto reductase
BM45_RS01845	COG1560	Kdo2-lipid A biosynthetic process
BM45_RS01860	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BM45_RS01870	COG0523	cobalamin synthesis protein
BM45_RS01890	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BM45_RS01915	COG1309	transcriptional regulator
BM45_RS01930	COG2814	Major facilitator Superfamily
BM45_RS01940	COG2207	Transcriptional regulator
BM45_RS01950	COG1064	alcohol dehydrogenase
BM45_RS01970	COG1596	polysaccharide export
BM45_RS01975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BM45_RS01990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BM45_RS02000	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BM45_RS02020	COG2204	response regulator
BM45_RS02055	COG5002	protein histidine kinase activity
BM45_RS02055	COG5001	Diguanylate cyclase
BM45_RS02060	COG0235	Class ii aldolase
BM45_RS02115	COG2801	Transposase and inactivated derivatives
BM45_RS02135	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BM45_RS02140	COG2801	Transposase and inactivated derivatives
BM45_RS02145	COG2963	transposase activity
BM45_RS02155	COG0592	DNA-directed DNA polymerase activity
BM45_RS02195	COG2801	Transposase and inactivated derivatives
BM45_RS02200	COG2963	transposase activity
BM45_RS02215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BM45_RS02215	COG2169	Transcriptional regulator
BM45_RS02230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BM45_RS02250	COG0583	DNA-binding transcription factor activity
BM45_RS02265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BM45_RS02275	COG4695	Portal protein
BM45_RS02295	COG2963	transposase activity
BM45_RS02325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BM45_RS02330	COG0583	DNA-binding transcription factor activity
BM45_RS02345	COG0758	DNA mediated transformation
BM45_RS02350	COG0242	peptide deformylase activity
BM45_RS02355	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BM45_RS02370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BM45_RS02370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BM45_RS02380	COG5000	phosphorelay sensor kinase activity
BM45_RS02385	COG2204	response regulator
BM45_RS02400	COG0602	queuosine metabolic process
BM45_RS02405	COG0720	synthase
BM45_RS02420	COG0772	Belongs to the SEDS family
BM45_RS02425	COG0768	penicillin binding
BM45_RS02440	COG1077	Cell shape determining protein MreB Mrl
BM45_RS02460	COG2326	polyphosphate kinase activity
BM45_RS02465	COG0708	Exodeoxyribonuclease III
BM45_RS02490	COG0477	Major facilitator Superfamily
BM45_RS02515	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BM45_RS02525	COG0251	oxidation-reduction process
BM45_RS02535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BM45_RS02600	COG0494	nUDIX hydrolase
BM45_RS02615	COG1960	acyl-CoA dehydrogenase activity
BM45_RS02620	COG1024	Enoyl-CoA hydratase
BM45_RS02620	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM45_RS02625	COG0183	Belongs to the thiolase family
BM45_RS02630	COG1024	Enoyl-CoA hydratase
BM45_RS02635	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BM45_RS02650	COG5265	(ABC) transporter
BM45_RS02660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BM45_RS02675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BM45_RS02680	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BM45_RS02705	COG0204	Acyl-transferase
BM45_RS02710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BM45_RS02715	COG0751	glycine-tRNA ligase activity
BM45_RS02720	COG0752	glycyl-tRNA synthetase alpha subunit
BM45_RS02725	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BM45_RS02735	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BM45_RS02745	COG1702	phosphate starvation-inducible protein PhoH
BM45_RS02755	COG0583	DNA-binding transcription factor activity
BM45_RS02760	COG2814	Major facilitator Superfamily
BM45_RS02765	COG1396	sequence-specific DNA binding
BM45_RS02775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM45_RS02790	COG0367	asparagine synthase
BM45_RS02795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BM45_RS02800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BM45_RS02810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BM45_RS02815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BM45_RS02855	COG0513	Belongs to the DEAD box helicase family
BM45_RS02875	COG4948	Mandelate Racemase Muconate Lactonizing
BM45_RS02915	COG0840	transmembrane signaling receptor activity
BM45_RS02920	COG2963	transposase activity
BM45_RS02925	COG2801	Transposase and inactivated derivatives
BM45_RS02940	COG3307	-O-antigen
BM45_RS02945	COG4969	Belongs to the N-Me-Phe pilin family
BM45_RS02950	COG0861	Integral membrane protein TerC family
BM45_RS02955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BM45_RS02970	COG2137	regulation of response to DNA damage stimulus
BM45_RS02975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BM45_RS03005	COG2801	Transposase and inactivated derivatives
BM45_RS03010	COG2801	Transposase and inactivated derivatives
BM45_RS03025	COG4783	chaperone-mediated protein folding
BM45_RS03035	COG0429	hydrolase of the alpha beta-hydrolase fold
BM45_RS03045	COG0859	PFAM glycosyl transferase family 9
BM45_RS03070	COG0126	phosphoglycerate kinase activity
BM45_RS03075	COG0469	pyruvate kinase activity
BM45_RS03085	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BM45_RS03090	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BM45_RS03095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BM45_RS03100	COG0009	L-threonylcarbamoyladenylate synthase
BM45_RS03130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BM45_RS03155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM45_RS03160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM45_RS03175	COG2233	PERMEase
BM45_RS03180	COG2963	transposase activity
BM45_RS03190	COG2233	PERMEase
BM45_RS03195	COG1070	Carbohydrate kinase
BM45_RS03210	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BM45_RS03215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BM45_RS03220	COG1121	(ABC) transporter
BM45_RS03230	COG0735	belongs to the Fur family
BM45_RS03240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM45_RS03255	COG1175	transmembrane transport
BM45_RS03265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM45_RS03270	COG3842	ATPase activity
BM45_RS03280	COG0583	DNA-binding transcription factor activity
BM45_RS03295	COG2390	Transcriptional regulator
BM45_RS03300	COG1070	Carbohydrate kinase
BM45_RS03305	COG0246	Mannitol dehydrogenase
BM45_RS03310	COG0583	DNA-binding transcription factor activity
BM45_RS03320	COG1012	belongs to the aldehyde dehydrogenase family
BM45_RS03325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BM45_RS03335	COG2271	Major facilitator Superfamily
BM45_RS03355	COG1522	sequence-specific DNA binding
BM45_RS03360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BM45_RS03370	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BM45_RS03385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BM45_RS03395	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BM45_RS03410	COG1741	Belongs to the pirin family
BM45_RS03420	COG0860	N-Acetylmuramoyl-L-alanine amidase
BM45_RS03425	COG0802	atpase or kinase
BM45_RS03430	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BM45_RS03440	COG4974	Belongs to the 'phage' integrase family
BM45_RS03445	COG0318	PFAM AMP-dependent synthetase and ligase
BM45_RS03450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BM45_RS03455	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BM45_RS03465	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BM45_RS03470	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BM45_RS03485	COG0728	peptidoglycan biosynthetic process
BM45_RS03510	COG2963	transposase activity
BM45_RS03515	COG2801	Transposase and inactivated derivatives
BM45_RS03550	COG1773	rubredoxin
BM45_RS03560	COG0488	(ABC) transporter
BM45_RS03585	COG0583	DNA-binding transcription factor activity
BM45_RS03595	COG0583	DNA-binding transcription factor activity
BM45_RS03600	COG0477	Major facilitator Superfamily
BM45_RS03640	COG2801	Transposase and inactivated derivatives
BM45_RS03645	COG2963	transposase activity
BM45_RS03655	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BM45_RS03680	COG0859	PFAM glycosyl transferase family 9
BM45_RS03735	COG1129	ABC transporter
BM45_RS03745	COG0559	Belongs to the binding-protein-dependent transport system permease family
BM45_RS03755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BM45_RS03765	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BM45_RS03775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BM45_RS03795	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BM45_RS03805	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BM45_RS03810	COG2226	methyltransferase
BM45_RS03835	COG0762	integral membrane protein
BM45_RS03860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BM45_RS03870	COG0436	Aminotransferase
BM45_RS03895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BM45_RS03895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BM45_RS03915	COG2814	Major facilitator Superfamily
BM45_RS03930	COG1126	abc transporter atp-binding protein
BM45_RS03935	COG0765	amino acid transport
BM45_RS03940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM45_RS03950	COG0363	glucosamine-6-phosphate deaminase activity
BM45_RS03955	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BM45_RS03965	COG1175	transmembrane transport
BM45_RS03970	COG0395	ABC-type sugar transport system, permease component
BM45_RS03975	COG3842	ATPase activity
BM45_RS03980	COG2860	membrane
BM45_RS03985	COG1193	negative regulation of DNA recombination
BM45_RS03990	COG0492	ferredoxin-NADP+ reductase activity
BM45_RS03995	COG1674	ftsk spoiiie
BM45_RS04000	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BM45_RS04010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BM45_RS04045	COG2894	cell division
BM45_RS04070	COG0859	PFAM glycosyl transferase family 9
BM45_RS04080	COG0477	Major facilitator Superfamily
BM45_RS04110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BM45_RS04115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BM45_RS04125	COG1561	YicC-like family, N-terminal region
BM45_RS04140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BM45_RS04175	COG2963	transposase activity
BM45_RS04190	COG2885	chlorophyll binding
BM45_RS04195	COG0823	Involved in the tonB-independent uptake of proteins
BM45_RS04215	COG0824	Thioesterase
BM45_RS04220	COG4221	oxidoreductase activity
BM45_RS04275	COG0450	alkyl hydroperoxide reductase
BM45_RS04285	COG1960	acyl-CoA dehydrogenase activity
BM45_RS04310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM45_RS04320	COG2814	Major facilitator Superfamily
BM45_RS04340	COG2814	Major facilitator Superfamily
BM45_RS04345	COG0778	Nitroreductase
BM45_RS04350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BM45_RS04355	COG0583	DNA-binding transcription factor activity
BM45_RS04360	COG2963	transposase activity
BM45_RS04365	COG2801	Transposase and inactivated derivatives
BM45_RS04370	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BM45_RS04395	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BM45_RS04410	COG4774	siderophore transport
BM45_RS04415	COG1120	ATPase activity
BM45_RS04430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BM45_RS04465	COG0730	response to heat
BM45_RS04475	COG0584	glycerophosphoryl diester phosphodiesterase
BM45_RS04485	COG1280	lysine exporter protein (LysE YggA)
BM45_RS04535	COG0604	alcohol dehydrogenase
BM45_RS04540	COG1733	regulation of RNA biosynthetic process
BM45_RS04550	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BM45_RS04565	COG1773	rubredoxin
BM45_RS04585	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BM45_RS04660	COG1215	transferase activity, transferring glycosyl groups
BM45_RS04675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BM45_RS04685	COG2801	Transposase and inactivated derivatives
BM45_RS04690	COG2963	transposase activity
BM45_RS04695	COG0534	Mate efflux family protein
BM45_RS04700	COG2501	S4 domain
BM45_RS04715	COG3045	CreA protein
BM45_RS04730	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BM45_RS04735	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BM45_RS04755	COG1322	Protein conserved in bacteria
BM45_RS04770	COG0303	'Molybdopterin
BM45_RS04780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BM45_RS04785	COG1530	ribonuclease E activity
BM45_RS04820	COG1399	metal-binding, possibly nucleic acid-binding protein
BM45_RS04855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BM45_RS04875	COG3026	antisigma factor binding
BM45_RS04880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BM45_RS04895	COG0681	Belongs to the peptidase S26 family
BM45_RS04900	COG0571	ribonuclease III activity
BM45_RS04905	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BM45_RS04910	COG1381	Involved in DNA repair and RecF pathway recombination
BM45_RS04915	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BM45_RS04930	COG2204	response regulator
BM45_RS04950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BM45_RS04975	COG1956	GAF domain-containing protein
BM45_RS04980	COG0583	DNA-binding transcription factor activity
BM45_RS04995	COG2153	protein acetylation
BM45_RS05010	COG1999	signal sequence binding
BM45_RS05020	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BM45_RS05025	COG1132	(ABC) transporter
BM45_RS05030	COG0438	transferase activity, transferring glycosyl groups
BM45_RS05045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BM45_RS05050	COG0683	leucine binding
BM45_RS05065	COG2963	transposase activity
BM45_RS05075	COG3394	polysaccharide catabolic process
BM45_RS05090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM45_RS05095	COG0596	Alpha beta hydrolase
BM45_RS05100	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BM45_RS05110	COG3511	phospholipase C
BM45_RS05115	COG2963	transposase activity
BM45_RS05140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BM45_RS05165	COG2988	succinylglutamate desuccinylase activity
BM45_RS05175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM45_RS05185	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BM45_RS05210	COG1959	2 iron, 2 sulfur cluster binding
BM45_RS05220	COG2151	metal-sulfur cluster biosynthetic enzyme
BM45_RS05225	COG0822	iron-sulfur transferase activity
BM45_RS05230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BM45_RS05240	COG0396	ATPase activity
BM45_RS05255	COG0840	transmembrane signaling receptor activity
BM45_RS05260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BM45_RS05265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BM45_RS05280	COG0826	peptidase U32
BM45_RS05285	COG0826	peptidase U32
BM45_RS05290	COG3154	lipid carrier protein
BM45_RS05325	COG2151	metal-sulfur cluster biosynthetic enzyme
BM45_RS05345	COG0415	Belongs to the DNA photolyase family
BM45_RS05350	COG0529	Catalyzes the synthesis of activated sulfate
BM45_RS05385	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BM45_RS05400	COG0402	S-adenosylhomocysteine deaminase activity
BM45_RS05425	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BM45_RS05430	COG0174	glutamine synthetase
BM45_RS05440	COG2963	transposase activity
BM45_RS05445	COG2801	Transposase and inactivated derivatives
BM45_RS05455	COG0583	DNA-binding transcription factor activity
BM45_RS05470	COG0175	sulfate reduction
BM45_RS05480	COG2895	sulfate adenylyltransferase (ATP) activity
BM45_RS05485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BM45_RS05485	COG1648	precorrin-2 dehydrogenase activity
BM45_RS05500	COG0795	lipopolysaccharide-transporting ATPase activity
BM45_RS05520	COG4654	Cytochrome c, class I
BM45_RS05535	COG0583	DNA-binding transcription factor activity
BM45_RS05565	COG4206	TonB-dependent receptor
BM45_RS05575	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BM45_RS05580	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BM45_RS05585	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BM45_RS05600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BM45_RS05620	COG1492	cobalamin metabolic process
BM45_RS05625	COG2259	Doxx family
BM45_RS05630	COG0489	protein tyrosine kinase activity
BM45_RS05645	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BM45_RS05655	COG0729	surface antigen
BM45_RS05660	COG2911	Protein conserved in bacteria
BM45_RS05680	COG3047	cAMP biosynthetic process
BM45_RS05680	COG2885	chlorophyll binding
BM45_RS05685	COG0489	protein tyrosine kinase activity
BM45_RS05710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM45_RS05745	COG2226	methyltransferase
BM45_RS05780	COG2271	Major facilitator Superfamily
BM45_RS05795	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BM45_RS05825	COG0347	Belongs to the P(II) protein family
BM45_RS05845	COG4215	(ABC) transporter
BM45_RS05885	COG1176	ABC-type spermidine putrescine transport system, permease component I
BM45_RS05890	COG1116	anion transmembrane transporter activity
BM45_RS05895	COG2801	Transposase and inactivated derivatives
BM45_RS05905	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BM45_RS05920	COG2814	Major facilitator Superfamily
BM45_RS05925	COG1881	PFAM PEBP family protein
BM45_RS05970	COG2801	Transposase and inactivated derivatives
BM45_RS05990	COG0583	DNA-binding transcription factor activity
BM45_RS05995	COG1960	acyl-CoA dehydrogenase activity
BM45_RS06005	COG0477	Major facilitator Superfamily
BM45_RS06015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BM45_RS06015	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BM45_RS06020	COG1643	Atp-dependent helicase
BM45_RS06040	COG1546	Belongs to the CinA family
BM45_RS06040	COG1058	Belongs to the CinA family
BM45_RS06050	COG0174	glutamine synthetase
BM45_RS06075	COG2197	response regulator
BM45_RS06080	COG4585	Histidine kinase
BM45_RS06085	COG2181	nitrate reductase activity
BM45_RS06090	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BM45_RS06095	COG1140	nitrate reductase beta subunit
BM45_RS06100	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BM45_RS06105	COG2223	nitrite transmembrane transporter activity
BM45_RS06120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BM45_RS06125	COG0339	signal peptide processing
BM45_RS06135	COG4566	intracellular signal transduction
BM45_RS06145	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BM45_RS06150	COG0508	dehydrogenase complex catalyzes the overall conversion of
BM45_RS06155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM45_RS06180	COG1414	Transcriptional regulator
BM45_RS06200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BM45_RS06210	COG1104	cysteine desulfurase activity
BM45_RS06215	COG0822	iron-sulfur transferase activity
BM45_RS06220	COG0316	Belongs to the HesB IscA family
BM45_RS06240	COG2975	iron-sulfur cluster assembly
BM45_RS06260	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BM45_RS06275	COG1136	(ABC) transporter
BM45_RS06280	COG0084	hydrolase, TatD family'
BM45_RS06285	COG2333	competence protein COMEC
BM45_RS06285	COG0658	competence protein
BM45_RS06310	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BM45_RS06320	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BM45_RS06330	COG2833	Protein of unknown function (DUF455)
BM45_RS06335	COG0596	Alpha beta hydrolase
BM45_RS06340	COG0613	PHP domain protein
BM45_RS06345	COG0009	L-threonylcarbamoyladenylate synthase
BM45_RS06350	COG1994	Peptidase M50
BM45_RS06355	COG0180	Tryptophanyl-tRNA synthetase
BM45_RS06365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BM45_RS06370	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BM45_RS06375	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BM45_RS06385	COG2850	peptidyl-arginine hydroxylation
BM45_RS06415	COG0483	inositol monophosphate 1-phosphatase activity
BM45_RS06425	COG1045	serine acetyltransferase
BM45_RS06430	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BM45_RS06440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BM45_RS06465	COG0037	tRNA processing
BM45_RS06470	COG0527	aspartate kinase activity
BM45_RS06500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM45_RS06505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM45_RS06510	COG0529	Catalyzes the synthesis of activated sulfate
BM45_RS06510	COG2895	sulfate adenylyltransferase (ATP) activity
BM45_RS06515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BM45_RS06545	COG2175	clavaminate synthase activity
BM45_RS06565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BM45_RS06570	COG3958	Transketolase
BM45_RS06585	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BM45_RS06605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BM45_RS06620	COG0024	Methionine aminopeptidase
BM45_RS06645	COG0243	molybdopterin cofactor binding
BM45_RS06665	COG4166	transmembrane transport
BM45_RS06670	COG4174	ABC transporter (Permease)
BM45_RS06675	COG4239	(ABC) transporter, permease
BM45_RS06680	COG4172	Belongs to the ABC transporter superfamily
BM45_RS06685	COG0791	NLP P60 protein
BM45_RS06690	COG1752	Esterase of the alpha-beta hydrolase superfamily
BM45_RS06740	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BM45_RS06750	COG0583	DNA-binding transcription factor activity
BM45_RS06760	COG2224	Isocitrate lyase
BM45_RS06770	COG0513	Belongs to the DEAD box helicase family
BM45_RS06780	COG1214	PFAM Peptidase M22, glycoprotease
BM45_RS06790	COG1573	uracil-dna glycosylase
BM45_RS06800	COG0351	phosphomethylpyrimidine kinase
BM45_RS06805	COG0477	Major facilitator Superfamily
BM45_RS06825	COG0488	(ABC) transporter
BM45_RS06830	COG0386	Belongs to the glutathione peroxidase family
BM45_RS06845	COG2890	protein-(glutamine-N5) methyltransferase activity
BM45_RS06855	COG1393	Belongs to the ArsC family
BM45_RS06895	COG0242	peptide deformylase activity
BM45_RS06900	COG1187	pseudouridine synthase activity
BM45_RS06910	COG0024	Methionine aminopeptidase
BM45_RS06940	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BM45_RS06955	COG0750	zinc metalloprotease
BM45_RS06995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BM45_RS07030	COG0330	HflC and HflK could
BM45_RS07040	COG2867	negative regulation of translational initiation
BM45_RS07050	COG0697	spore germination
BM45_RS07105	COG1619	proteins homologs of microcin C7 resistance protein MccF
BM45_RS07120	COG1953	Uracil, thiamine, allantoin
BM45_RS07135	COG3195	allantoin biosynthetic process
BM45_RS07135	COG3648	Uricase
BM45_RS07140	COG4266	Belongs to the allantoicase family
BM45_RS07205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BM45_RS07220	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BM45_RS07265	COG2963	transposase activity
BM45_RS07270	COG2801	Transposase and inactivated derivatives
BM45_RS07305	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BM45_RS07310	COG1846	Transcriptional regulator
BM45_RS07315	COG1929	Belongs to the glycerate kinase type-1 family
BM45_RS07335	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BM45_RS07385	COG4181	ATPase activity
BM45_RS07400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BM45_RS07410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BM45_RS07410	COG0047	phosphoribosylformylglycinamidine synthase activity
BM45_RS07420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BM45_RS07445	COG0318	PFAM AMP-dependent synthetase and ligase
BM45_RS07450	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM45_RS07450	COG1024	Enoyl-CoA hydratase
BM45_RS07455	COG1335	isochorismatase
BM45_RS07460	COG0183	Belongs to the thiolase family
BM45_RS07480	COG2130	NADP-dependent
BM45_RS07485	COG0657	acetylesterase activity
BM45_RS07500	COG0354	folic acid binding
BM45_RS07505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BM45_RS07520	COG1247	-acetyltransferase
BM45_RS07525	COG0084	hydrolase, TatD family'
BM45_RS07550	COG0438	transferase activity, transferring glycosyl groups
BM45_RS07570	COG0252	asparaginase activity
BM45_RS07585	COG2801	Transposase and inactivated derivatives
BM45_RS07590	COG2963	transposase activity
BM45_RS07595	COG2801	Transposase and inactivated derivatives
BM45_RS07610	COG1595	DNA-templated transcription, initiation
BM45_RS07650	COG0306	phosphate transporter
BM45_RS07655	COG0791	NLP P60 protein
BM45_RS07660	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BM45_RS07665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BM45_RS07670	COG0726	polysaccharide deacetylase
BM45_RS07675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BM45_RS07675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BM45_RS07685	COG0463	Glycosyl transferase, family 2
BM45_RS07690	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BM45_RS07695	COG2076	Multidrug Resistance protein
BM45_RS07700	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BM45_RS07710	COG0436	Aminotransferase
BM45_RS07730	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BM45_RS07735	COG0314	molybdopterin synthase activity
BM45_RS07740	COG2346	COG2346, Truncated hemoglobins
BM45_RS07745	COG1959	2 iron, 2 sulfur cluster binding
BM45_RS07750	COG0542	response to heat
BM45_RS07775	COG0534	Mate efflux family protein
BM45_RS07790	COG3228	Belongs to the MtfA family
BM45_RS07795	COG0477	Major facilitator Superfamily
BM45_RS07800	COG0789	Transcriptional regulator
BM45_RS07805	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BM45_RS07820	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BM45_RS07835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BM45_RS07880	COG0670	Belongs to the BI1 family
BM45_RS07915	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM45_RS07930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BM45_RS07935	COG0330	HflC and HflK could
BM45_RS07940	COG0330	HflC and HflK could
BM45_RS07960	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BM45_RS07970	COG2183	response to ionizing radiation
BM45_RS07985	COG1199	ATP-dependent helicase activity
BM45_RS07995	COG0564	pseudouridine synthase activity
BM45_RS08005	COG3243	poly(R)-hydroxyalkanoic acid synthase
BM45_RS08010	COG0183	Belongs to the thiolase family
BM45_RS08015	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS08035	COG0183	Belongs to the thiolase family
BM45_RS08045	COG0626	cystathionine gamma-synthase activity
BM45_RS08050	COG0560	Phosphoserine phosphatase
BM45_RS08060	COG0390	transport system, permease component
BM45_RS08065	COG1122	ATPase activity
BM45_RS08070	COG2982	Protein involved in outer membrane biogenesis
BM45_RS08075	COG0488	(ABC) transporter
BM45_RS08090	COG2070	2-Nitropropane dioxygenase
BM45_RS08095	COG3047	cAMP biosynthetic process
BM45_RS08105	COG1914	H( )-stimulated, divalent metal cation uptake system
BM45_RS08110	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BM45_RS08115	COG3842	ATPase activity
BM45_RS08120	COG1176	ABC-type spermidine putrescine transport system, permease component I
BM45_RS08125	COG1177	transmembrane transport
BM45_RS08135	COG2963	transposase activity
BM45_RS08140	COG2801	Transposase and inactivated derivatives
BM45_RS08165	COG4964	Belongs to the GSP D family
BM45_RS08230	COG0318	PFAM AMP-dependent synthetase and ligase
BM45_RS08240	COG2814	Major facilitator Superfamily
BM45_RS08250	COG0519	Catalyzes the synthesis of GMP from XMP
BM45_RS08275	COG0840	transmembrane signaling receptor activity
BM45_RS08295	COG0557	exoribonuclease II activity
BM45_RS08300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BM45_RS08310	COG3023	N-Acetylmuramoyl-L-alanine amidase
BM45_RS08320	COG1802	Transcriptional regulator
BM45_RS08325	COG0673	inositol 2-dehydrogenase activity
BM45_RS08330	COG2801	Transposase and inactivated derivatives
BM45_RS08340	COG2192	nodulation
BM45_RS08345	COG2963	transposase activity
BM45_RS08350	COG2801	Transposase and inactivated derivatives
BM45_RS08380	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BM45_RS08385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM45_RS08390	COG0508	dehydrogenase complex catalyzes the overall conversion of
BM45_RS08395	COG0567	Dehydrogenase, E1 component
BM45_RS08400	COG1217	gtp-binding protein TYPA
BM45_RS08405	COG1846	Transcriptional regulator
BM45_RS08415	COG1566	PFAM secretion protein HlyD family protein
BM45_RS08420	COG2814	Major facilitator Superfamily
BM45_RS08425	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BM45_RS08440	COG0195	Participates in both transcription termination and antitermination
BM45_RS08440	COG2251	uridine kinase activity
BM45_RS08450	COG1187	pseudouridine synthase activity
BM45_RS08455	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BM45_RS08460	COG0583	DNA-binding transcription factor activity
BM45_RS08500	COG2963	transposase activity
BM45_RS08515	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BM45_RS08545	COG0776	regulation of translation
BM45_RS08550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BM45_RS08550	COG0072	phenylalanine-tRNA ligase activity
BM45_RS08570	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BM45_RS08585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BM45_RS08590	COG0251	oxidation-reduction process
BM45_RS08595	COG2267	carboxylic ester hydrolase activity
BM45_RS08605	COG0583	DNA-binding transcription factor activity
BM45_RS08620	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS08655	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS08665	COG2801	Transposase and inactivated derivatives
BM45_RS08670	COG2963	transposase activity
BM45_RS08680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BM45_RS08695	COG3251	PFAM MbtH domain protein
BM45_RS08715	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS08720	COG2207	Transcriptional regulator
BM45_RS08730	COG0835	chemotaxis
BM45_RS08750	COG0318	PFAM AMP-dependent synthetase and ligase
BM45_RS08755	COG0477	Major facilitator Superfamily
BM45_RS08765	COG1732	Glycine betaine
BM45_RS08770	COG1174	glycine betaine transport
BM45_RS08775	COG1125	glycine betaine transport
BM45_RS08780	COG1174	glycine betaine transport
BM45_RS08795	COG2235	arginine
BM45_RS08800	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BM45_RS08820	COG0583	DNA-binding transcription factor activity
BM45_RS08830	COG0625	glutathione transferase activity
BM45_RS08845	COG1846	Transcriptional regulator
BM45_RS08855	COG1649	PFAM Uncharacterised BCR, COG1649
BM45_RS08875	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BM45_RS08885	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BM45_RS08905	COG3979	chitinase
BM45_RS08915	COG0400	carboxylic ester hydrolase activity
BM45_RS08945	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BM45_RS08970	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BM45_RS08975	COG4774	siderophore transport
BM45_RS08980	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BM45_RS09020	COG1120	ATPase activity
BM45_RS09045	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS09050	COG1070	Carbohydrate kinase
BM45_RS09055	COG1063	alcohol dehydrogenase
BM45_RS09060	COG1172	Belongs to the binding-protein-dependent transport system permease family
BM45_RS09070	COG1879	ABC-type sugar transport system periplasmic component
BM45_RS09095	COG2963	transposase activity
BM45_RS09105	COG2375	cellular response to nickel ion
BM45_RS09105	COG1132	(ABC) transporter
BM45_RS09115	COG3121	Chaperone
BM45_RS09120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM45_RS09130	COG1309	transcriptional regulator
BM45_RS09135	COG0739	heme binding
BM45_RS09140	COG0765	amino acid transport
BM45_RS09145	COG4597	amino acid ABC transporter
BM45_RS09160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM45_RS09205	COG4964	Belongs to the GSP D family
BM45_RS09225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BM45_RS09230	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BM45_RS09245	COG0477	Major facilitator Superfamily
BM45_RS09250	COG2719	SpoVR family
BM45_RS09255	COG2718	Belongs to the UPF0229 family
BM45_RS09260	COG2766	serine protein kinase
BM45_RS09265	COG2801	Transposase and inactivated derivatives
BM45_RS09275	COG0583	DNA-binding transcription factor activity
BM45_RS09280	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BM45_RS09285	COG4208	sulfate ABC transporter
BM45_RS09290	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BM45_RS09295	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BM45_RS09335	COG0701	Predicted permease
BM45_RS09340	COG0667	Aldo Keto reductase
BM45_RS09365	COG1301	dicarboxylic acid transport
BM45_RS09390	COG2801	Transposase and inactivated derivatives
BM45_RS09420	COG1116	anion transmembrane transporter activity
BM45_RS09425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BM45_RS09480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM45_RS09485	COG0765	amino acid transport
BM45_RS09490	COG2963	transposase activity
BM45_RS09495	COG2801	Transposase and inactivated derivatives
BM45_RS09500	COG2801	Transposase and inactivated derivatives
BM45_RS09525	COG0477	Major facilitator Superfamily
BM45_RS09540	COG1295	ribonuclease BN
BM45_RS09555	COG0277	FAD linked oxidase domain protein
BM45_RS09570	COG0583	DNA-binding transcription factor activity
BM45_RS09600	COG0840	transmembrane signaling receptor activity
BM45_RS09605	COG2223	nitrite transmembrane transporter activity
BM45_RS09610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BM45_RS09615	COG0210	DNA helicase
BM45_RS09620	COG0525	valine-tRNA ligase activity
BM45_RS09625	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BM45_RS09635	COG5002	protein histidine kinase activity
BM45_RS09645	COG0745	RESPONSE REGULATOR receiver
BM45_RS09655	COG0425	Belongs to the sulfur carrier protein TusA family
BM45_RS09660	COG0673	inositol 2-dehydrogenase activity
BM45_RS09665	COG0673	inositol 2-dehydrogenase activity
BM45_RS09680	COG1172	Belongs to the binding-protein-dependent transport system permease family
BM45_RS09695	COG3962	Belongs to the TPP enzyme family
BM45_RS09705	COG3718	enzyme involved in inositol metabolism
BM45_RS09715	COG0411	ABC transporter
BM45_RS09725	COG0824	Thioesterase
BM45_RS09740	COG2816	NAD+ diphosphatase activity
BM45_RS09750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BM45_RS09755	COG0477	Major facilitator Superfamily
BM45_RS09760	COG2801	Transposase and inactivated derivatives
BM45_RS09765	COG2963	transposase activity
BM45_RS09790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BM45_RS09800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BM45_RS09805	COG1051	belongs to the nudix hydrolase family
BM45_RS09825	COG1858	cytochrome C peroxidase
BM45_RS09830	COG3511	phospholipase C
BM45_RS09840	COG1566	PFAM secretion protein HlyD family protein
BM45_RS09845	COG2814	Major facilitator Superfamily
BM45_RS09855	COG1538	Outer membrane efflux protein
BM45_RS09860	COG2197	response regulator
BM45_RS09900	COG0583	DNA-binding transcription factor activity
BM45_RS09905	COG2814	Major facilitator Superfamily
BM45_RS09930	COG1914	H( )-stimulated, divalent metal cation uptake system
BM45_RS09940	COG2963	transposase activity
BM45_RS09945	COG2801	Transposase and inactivated derivatives
BM45_RS10015	COG0457	Tetratricopeptide repeat
BM45_RS10015	COG0859	PFAM glycosyl transferase family 9
BM45_RS10065	COG0745	RESPONSE REGULATOR receiver
BM45_RS10070	COG0583	DNA-binding transcription factor activity
BM45_RS10105	COG0366	Alpha amylase catalytic
BM45_RS10110	COG0366	Alpha amylase catalytic
BM45_RS10155	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BM45_RS10185	COG2963	transposase activity
BM45_RS10195	COG4942	peptidase
BM45_RS10200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BM45_RS10210	COG0534	Mate efflux family protein
BM45_RS10275	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BM45_RS10285	COG0745	RESPONSE REGULATOR receiver
BM45_RS10300	COG0581	inorganic phosphate transmembrane transporter activity
BM45_RS10305	COG0573	inorganic phosphate transmembrane transporter activity
BM45_RS10310	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BM45_RS10320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BM45_RS10325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BM45_RS10335	COG1534	Rna-binding protein
BM45_RS10345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BM45_RS10350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BM45_RS10360	COG0505	Belongs to the CarA family
BM45_RS10380	COG0741	lytic transglycosylase activity
BM45_RS10380	COG1388	LysM domain
BM45_RS10385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BM45_RS10390	COG2226	methyltransferase
BM45_RS10395	COG0328	RNA-DNA hybrid ribonuclease activity
BM45_RS10400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BM45_RS10410	COG0477	Major facilitator Superfamily
BM45_RS10430	COG2801	Transposase and inactivated derivatives
BM45_RS10450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BM45_RS10460	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BM45_RS10480	COG3052	prosthetic group binding
BM45_RS10505	COG0583	DNA-binding transcription factor activity
BM45_RS10510	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM45_RS10515	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BM45_RS10545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BM45_RS10575	COG0583	DNA-binding transcription factor activity
BM45_RS10595	COG1522	sequence-specific DNA binding
BM45_RS10640	COG1609	Transcriptional regulator
BM45_RS10645	COG1840	ABC-type Fe3 transport system, periplasmic component
BM45_RS10650	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BM45_RS10665	COG1177	transmembrane transport
BM45_RS10670	COG3842	ATPase activity
BM45_RS10675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BM45_RS10695	COG2814	Major facilitator Superfamily
BM45_RS10700	COG0697	spore germination
BM45_RS10710	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BM45_RS10715	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BM45_RS10740	COG2963	transposase activity
BM45_RS10760	COG2200	EAL domain
BM45_RS10770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BM45_RS10775	COG1074	ATP-dependent DNA helicase activity
BM45_RS10780	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BM45_RS10795	COG1289	transmembrane transporter activity
BM45_RS10810	COG1840	ABC-type Fe3 transport system, periplasmic component
BM45_RS10815	COG1176	ABC-type spermidine putrescine transport system, permease component I
BM45_RS10820	COG3842	ATPase activity
BM45_RS10825	COG1522	sequence-specific DNA binding
BM45_RS10840	COG1959	2 iron, 2 sulfur cluster binding
BM45_RS10895	COG2866	Carboxypeptidase
BM45_RS10910	COG0436	Aminotransferase
BM45_RS10920	COG1024	Enoyl-CoA hydratase
BM45_RS10925	COG0588	phosphoglycerate mutase activity
BM45_RS10935	COG1960	acyl-CoA dehydrogenase activity
BM45_RS10955	COG2030	dehydratase
BM45_RS10955	COG1012	belongs to the aldehyde dehydrogenase family
BM45_RS10960	COG1960	acyl-CoA dehydrogenase activity
BM45_RS10965	COG1960	acyl-CoA dehydrogenase activity
BM45_RS10985	COG1007	ATP synthesis coupled electron transport
BM45_RS11020	COG1034	ATP synthesis coupled electron transport
BM45_RS11030	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BM45_RS11065	COG0149	triose-phosphate isomerase activity
BM45_RS11070	COG3321	synthase
BM45_RS11070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BM45_RS11070	COG0604	alcohol dehydrogenase
BM45_RS11070	COG4221	oxidoreductase activity
BM45_RS11085	COG0683	leucine binding
BM45_RS11095	COG0288	reversible hydration of carbon dioxide
BM45_RS11100	COG0659	secondary active sulfate transmembrane transporter activity
BM45_RS11110	COG1183	phosphatidylcholine synthase activity
BM45_RS11130	COG0028	Belongs to the TPP enzyme family
BM45_RS11160	COG0438	transferase activity, transferring glycosyl groups
BM45_RS11180	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS11185	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BM45_RS11200	COG0154	amidase activity
BM45_RS11210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BM45_RS11240	COG0745	RESPONSE REGULATOR receiver
BM45_RS11245	COG2205	protein histidine kinase activity
BM45_RS11260	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BM45_RS11265	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BM45_RS11285	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS11300	COG0151	Belongs to the GarS family
BM45_RS11315	COG0799	negative regulation of ribosome biogenesis
BM45_RS11335	COG2233	PERMEase
BM45_RS11370	COG1595	DNA-templated transcription, initiation
BM45_RS11375	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BM45_RS11405	COG0859	PFAM glycosyl transferase family 9
BM45_RS11410	COG0438	transferase activity, transferring glycosyl groups
BM45_RS11450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BM45_RS11455	COG0513	Belongs to the DEAD box helicase family
BM45_RS11485	COG1674	ftsk spoiiie
BM45_RS11495	COG2706	6-phosphogluconolactonase activity
BM45_RS11500	COG3387	PFAM Glycoside hydrolase 15-related
BM45_RS11510	COG1309	transcriptional regulator
BM45_RS11515	COG2878	Part of a membrane complex involved in electron transport
BM45_RS11520	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BM45_RS11560	COG3135	benzoate transporter
BM45_RS11575	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BM45_RS11590	COG4106	trans-aconitate 2-methyltransferase activity
BM45_RS11610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BM45_RS11620	COG0697	spore germination
BM45_RS11625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BM45_RS11630	COG2963	transposase activity
BM45_RS11635	COG2801	Transposase and inactivated derivatives
BM45_RS11645	COG1396	sequence-specific DNA binding
BM45_RS11655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BM45_RS11660	COG2258	MOSC domain
BM45_RS11665	COG2267	carboxylic ester hydrolase activity
BM45_RS11675	COG0583	DNA-binding transcription factor activity
BM45_RS11685	COG1187	pseudouridine synthase activity
BM45_RS11700	COG0543	2 iron, 2 sulfur cluster binding
BM45_RS11700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BM45_RS11705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BM45_RS11710	COG0456	acetyltransferase
BM45_RS11735	COG0559	Belongs to the binding-protein-dependent transport system permease family
BM45_RS11740	COG2963	transposase activity
BM45_RS11745	COG2801	Transposase and inactivated derivatives
BM45_RS11755	COG0114	fumarate hydratase activity
BM45_RS11770	COG0640	Transcriptional regulator
BM45_RS11785	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BM45_RS11820	COG2204	response regulator
BM45_RS11825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BM45_RS11835	COG0312	modulator of DNA gyrase
BM45_RS11840	COG3028	Belongs to the UPF0307 family
BM45_RS11845	COG0521	Mo-molybdopterin cofactor biosynthetic process
BM45_RS11855	COG0501	Belongs to the peptidase M48B family
BM45_RS11870	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BM45_RS11925	COG2801	Transposase and inactivated derivatives
BM45_RS11930	COG2963	transposase activity
BM45_RS11960	COG2011	ABC-type metal ion transport system permease component
BM45_RS11970	COG2267	carboxylic ester hydrolase activity
BM45_RS11975	COG0123	including yeast histone deacetylase and acetoin utilization protein
BM45_RS11980	COG2951	lytic endotransglycosylase activity
BM45_RS12005	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BM45_RS12015	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BM45_RS12045	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BM45_RS12050	COG1605	Chorismate mutase
BM45_RS12050	COG0077	Prephenate dehydratase
BM45_RS12055	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BM45_RS12080	COG0546	phosphoglycolate phosphatase activity
BM45_RS12085	COG2963	transposase activity
BM45_RS12090	COG2801	Transposase and inactivated derivatives
BM45_RS12095	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BM45_RS12105	COG1910	domain protein
BM45_RS12120	COG3383	formate dehydrogenase (NAD+) activity
BM45_RS12145	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BM45_RS12150	COG0154	amidase activity
BM45_RS12165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BM45_RS12170	COG2252	PERMEase
BM45_RS12175	COG0402	S-adenosylhomocysteine deaminase activity
BM45_RS12180	COG2119	membrane
BM45_RS12190	COG0308	aminopeptidase N
BM45_RS12200	COG0583	DNA-binding transcription factor activity
BM45_RS12250	COG4772	TonB-dependent receptor
BM45_RS12275	COG2963	transposase activity
BM45_RS12290	COG0582	viral genome integration into host DNA
BM45_RS12295	COG2963	transposase activity
BM45_RS12300	COG2801	Transposase and inactivated derivatives
BM45_RS12325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BM45_RS12330	COG1047	Peptidyl-prolyl cis-trans
BM45_RS12350	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BM45_RS12370	COG3264	Mechanosensitive ion channel
BM45_RS12370	COG1511	domain protein
BM45_RS12375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BM45_RS12375	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BM45_RS12380	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BM45_RS12385	COG0196	riboflavin kinase activity
BM45_RS12390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BM45_RS12420	COG2801	Transposase and inactivated derivatives
BM45_RS12435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BM45_RS12440	COG1570	exodeoxyribonuclease VII activity
BM45_RS12445	COG1663	tetraacyldisaccharide 4'-kinase activity
BM45_RS12470	COG1278	Cold shock
BM45_RS12480	COG0542	response to heat
BM45_RS12485	COG1113	amino acid transport
BM45_RS12490	COG2801	Transposase and inactivated derivatives
BM45_RS12515	COG0156	8-amino-7-oxononanoate synthase activity
BM45_RS12520	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BM45_RS12525	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS12525	COG0604	alcohol dehydrogenase
BM45_RS12525	COG3321	synthase
BM45_RS12530	COG1368	sulfuric ester hydrolase activity
BM45_RS12545	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BM45_RS12645	COG0586	Pfam SNARE associated Golgi protein
BM45_RS12650	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BM45_RS12670	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BM45_RS12680	COG0617	tRNA 3'-terminal CCA addition
BM45_RS12685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BM45_RS12690	COG1428	Deoxynucleoside kinase
BM45_RS12700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BM45_RS12745	COG0497	DNA recombination
BM45_RS12750	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BM45_RS12755	COG3164	Protein of unknown function
BM45_RS12760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BM45_RS12765	COG0312	modulator of DNA gyrase
BM45_RS12770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BM45_RS12800	COG4977	sequence-specific DNA binding
BM45_RS12800	COG1917	Cupin 2, conserved barrel domain protein
BM45_RS12805	COG0625	glutathione transferase activity
BM45_RS12810	COG0625	glutathione transferase activity
BM45_RS12820	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BM45_RS12830	COG0588	phosphoglycerate mutase activity
BM45_RS12870	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BM45_RS12875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BM45_RS12880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM45_RS12885	COG0006	proline dipeptidase activity
BM45_RS12890	COG0625	glutathione transferase activity
BM45_RS12900	COG0069	glutamate synthase activity
BM45_RS12970	COG3008	intermembrane lipid transfer
BM45_RS12970	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BM45_RS12975	COG2995	paraquat-inducible protein a
BM45_RS12990	COG2353	YceI-like domain
BM45_RS12995	COG2353	YceI-like domain
BM45_RS13005	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BM45_RS13010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BM45_RS13015	COG1862	Preprotein translocase
BM45_RS13020	COG0343	queuine tRNA-ribosyltransferase activity
BM45_RS13030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BM45_RS13050	COG0783	Belongs to the Dps family
BM45_RS13075	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BM45_RS13080	COG2188	Transcriptional regulator
BM45_RS13085	COG3624	Phosphonate C-P lyase system protein PhnG
BM45_RS13095	COG3626	phosphonate metabolism
BM45_RS13100	COG3627	carbon phosphorus lyase activity
BM45_RS13105	COG4107	phosphonate C-P lyase system protein PhnK
BM45_RS13110	COG4778	phosphonate C-P lyase system protein PhnL
BM45_RS13115	COG3454	Phosphonate metabolism
BM45_RS13120	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BM45_RS13125	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BM45_RS13135	COG3639	organic phosphonate transmembrane transporter activity
BM45_RS13150	COG0247	lactate metabolic process
BM45_RS13155	COG0277	FAD linked oxidase domain protein
BM45_RS13160	COG0277	FAD linked oxidase domain protein
BM45_RS13165	COG0277	FAD linked oxidase domain protein
BM45_RS13170	COG2096	Adenosyltransferase
BM45_RS13175	COG1017	nitric oxide dioxygenase activity
BM45_RS13175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BM45_RS13195	COG0418	dihydroorotase activity
BM45_RS13200	COG0121	glutamine amidotransferase
BM45_RS13230	COG1126	abc transporter atp-binding protein
BM45_RS13235	COG0765	amino acid transport
BM45_RS13240	COG0765	amino acid transport
BM45_RS13245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM45_RS13250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BM45_RS13255	COG0583	DNA-binding transcription factor activity
BM45_RS13260	COG2223	nitrite transmembrane transporter activity
BM45_RS13280	COG0800	Aldolase
BM45_RS13290	COG1737	Transcriptional regulator
BM45_RS13295	COG1981	membrane
BM45_RS13300	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BM45_RS13305	COG1466	dna polymerase III delta subunit
BM45_RS13335	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM45_RS13340	COG0735	belongs to the Fur family
BM45_RS13350	COG4266	Belongs to the allantoicase family
BM45_RS13355	COG1301	dicarboxylic acid transport
BM45_RS13360	COG2801	Transposase and inactivated derivatives
BM45_RS13365	COG2963	transposase activity
BM45_RS13370	COG1301	dicarboxylic acid transport
BM45_RS13380	COG0583	DNA-binding transcription factor activity
BM45_RS13395	COG2814	Major facilitator Superfamily
BM45_RS13400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BM45_RS13405	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BM45_RS13410	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BM45_RS13420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BM45_RS13450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BM45_RS13455	COG1546	Belongs to the CinA family
BM45_RS13460	COG0284	orotidine-5'-phosphate decarboxylase activity
BM45_RS13470	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS13475	COG1172	Belongs to the binding-protein-dependent transport system permease family
BM45_RS13480	COG1129	ABC transporter
BM45_RS13490	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS13500	COG3734	2-keto-3-deoxy-galactonokinase
BM45_RS13505	COG1414	Transcriptional regulator
BM45_RS13520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BM45_RS13525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BM45_RS13530	COG0557	exoribonuclease II activity
BM45_RS13535	COG3150	esterase
BM45_RS13540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BM45_RS13550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BM45_RS13555	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BM45_RS13560	COG0511	ligase activity, forming carbon-carbon bonds
BM45_RS13565	COG0439	Biotin carboxylase
BM45_RS13580	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BM45_RS13585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM45_RS13625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BM45_RS13630	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BM45_RS13635	COG2095	MarC family integral membrane protein
BM45_RS13680	COG0142	geranyltranstransferase activity
BM45_RS13695	COG2801	Transposase and inactivated derivatives
BM45_RS13700	COG2963	transposase activity
BM45_RS13705	COG4536	flavin adenine dinucleotide binding
BM45_RS13710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BM45_RS13720	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BM45_RS13735	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BM45_RS13740	COG0494	nUDIX hydrolase
BM45_RS13750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BM45_RS13775	COG0678	peroxiredoxin activity
BM45_RS13790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BM45_RS13825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BM45_RS13830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BM45_RS13840	COG3116	cell division
BM45_RS13860	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS13900	COG1024	Enoyl-CoA hydratase
BM45_RS13925	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BM45_RS13935	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BM45_RS13950	COG0737	Belongs to the 5'-nucleotidase family
BM45_RS13955	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BM45_RS13960	COG1127	ABC transporter
BM45_RS13990	COG1686	Belongs to the peptidase S11 family
BM45_RS14000	COG2921	Belongs to the UPF0250 family
BM45_RS14005	COG0583	DNA-binding transcription factor activity
BM45_RS14050	COG0583	DNA-binding transcription factor activity
BM45_RS14055	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM45_RS14055	COG1024	Enoyl-CoA hydratase
BM45_RS14060	COG1960	acyl-CoA dehydrogenase activity
BM45_RS14065	COG1960	acyl-CoA dehydrogenase activity
BM45_RS14070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BM45_RS14080	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM45_RS14100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BM45_RS14130	COG2960	long-chain fatty acid transporting porin activity
BM45_RS14140	COG0004	ammonium transporteR
BM45_RS14155	COG0189	ligase activity
BM45_RS14165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BM45_RS14170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BM45_RS14175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BM45_RS14180	COG0793	Belongs to the peptidase S41A family
BM45_RS14190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM45_RS14210	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BM45_RS14220	COG1040	competence protein
BM45_RS14225	COG2226	methyltransferase
BM45_RS14240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BM45_RS14250	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BM45_RS14280	COG1612	heme a metabolic process
BM45_RS14290	COG1999	signal sequence binding
BM45_RS14300	COG0840	transmembrane signaling receptor activity
BM45_RS14330	COG1294	oxidase, subunit
BM45_RS14350	COG1263	PTS System
BM45_RS14350	COG2190	(PTS) system
BM45_RS14350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BM45_RS14355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BM45_RS14355	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BM45_RS14360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BM45_RS14365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BM45_RS14370	COG2188	Transcriptional regulator
BM45_RS14375	COG0583	DNA-binding transcription factor activity
BM45_RS14430	COG1960	acyl-CoA dehydrogenase activity
BM45_RS14440	COG2226	methyltransferase
BM45_RS14475	COG2814	Major facilitator Superfamily
BM45_RS14485	COG0587	DNA-directed DNA polymerase activity
BM45_RS14500	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BM45_RS14520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BM45_RS14525	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BM45_RS14535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BM45_RS14545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BM45_RS14550	COG0243	molybdopterin cofactor binding
BM45_RS14560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BM45_RS14570	COG0625	glutathione transferase activity
BM45_RS14580	COG0742	ribosomal rna small subunit methyltransferase
BM45_RS14590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BM45_RS14595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BM45_RS14610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BM45_RS14625	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BM45_RS14640	COG1194	a g-specific adenine glycosylase
BM45_RS14665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BM45_RS14670	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BM45_RS14675	COG1137	ATPase activity
BM45_RS14690	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BM45_RS14710	COG1280	lysine exporter protein (LysE YggA)
BM45_RS14735	COG2814	Major facilitator Superfamily
BM45_RS14740	COG0629	single-stranded DNA binding
BM45_RS14745	COG2963	transposase activity
BM45_RS14750	COG2801	Transposase and inactivated derivatives
BM45_RS14755	COG0582	viral genome integration into host DNA
BM45_RS14765	COG3245	cytochrome
BM45_RS14770	COG0210	DNA helicase
BM45_RS14785	COG0673	inositol 2-dehydrogenase activity
BM45_RS14800	COG0509	glycine decarboxylation via glycine cleavage system
BM45_RS14815	COG1760	l-serine dehydratase
BM45_RS14840	COG1012	belongs to the aldehyde dehydrogenase family
BM45_RS14850	COG4302	ethanolamine ammonia-lyase activity
BM45_RS14855	COG4303	Ethanolamine ammonia lyase large subunit
BM45_RS14865	COG0531	amino acid
BM45_RS14885	COG0668	transmembrane transport
BM45_RS14905	COG0789	Transcriptional regulator
BM45_RS14915	COG0277	FAD linked oxidase domain protein
BM45_RS14935	COG0436	Aminotransferase
BM45_RS14945	COG1960	acyl-CoA dehydrogenase activity
BM45_RS14960	COG0506	proline dehydrogenase activity
BM45_RS14960	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BM45_RS14960	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BM45_RS14970	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BM45_RS14985	COG1832	CoA-binding protein
BM45_RS14990	COG0318	PFAM AMP-dependent synthetase and ligase
BM45_RS15035	COG0356	it plays a direct role in the translocation of protons across the membrane
BM45_RS15045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BM45_RS15050	COG1475	DNA binding
BM45_RS15055	COG1192	Involved in chromosome partitioning
BM45_RS15100	COG0559	Belongs to the binding-protein-dependent transport system permease family
BM45_RS15120	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BM45_RS15130	COG0583	DNA-binding transcription factor activity
BM45_RS15140	COG1522	sequence-specific DNA binding
BM45_RS15145	COG3186	Phenylalanine-4-hydroxylase
BM45_RS15165	COG0642	Histidine kinase
BM45_RS15180	COG1902	pentaerythritol trinitrate reductase activity
BM45_RS15185	COG0519	Catalyzes the synthesis of GMP from XMP
BM45_RS15185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BM45_RS15225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BM45_RS15235	COG1522	sequence-specific DNA binding
BM45_RS15240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BM45_RS15270	COG2963	transposase activity
BM45_RS15280	COG3397	chitin binding
BM45_RS15300	COG2267	carboxylic ester hydrolase activity
BM45_RS15330	COG1280	lysine exporter protein (LysE YggA)
BM45_RS15355	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS15370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BM45_RS15405	COG0519	Catalyzes the synthesis of GMP from XMP
BM45_RS15415	COG0561	phosphatase activity
BM45_RS15420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BM45_RS15430	COG0438	transferase activity, transferring glycosyl groups
BM45_RS15450	COG1360	Flagellar Motor Protein
BM45_RS15455	COG2201	protein-glutamate methylesterase activity
BM45_RS15475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BM45_RS15485	COG2201	protein-glutamate methylesterase activity
BM45_RS15490	COG0745	RESPONSE REGULATOR receiver
BM45_RS15495	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BM45_RS15515	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BM45_RS15520	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BM45_RS15545	COG1950	PFAM Membrane protein of
BM45_RS15550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BM45_RS15575	COG2801	Transposase and inactivated derivatives
BM45_RS15660	COG0308	aminopeptidase N
BM45_RS15705	COG0443	Heat shock 70 kDa protein
BM45_RS15725	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BM45_RS15730	COG2823	Periplasmic or secreted lipoprotein
BM45_RS15745	COG1113	amino acid transport
BM45_RS15760	COG1278	Cold shock
BM45_RS15805	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BM45_RS15815	COG1175	transmembrane transport
BM45_RS15820	COG0395	ABC-type sugar transport system, permease component
BM45_RS15825	COG3842	ATPase activity
BM45_RS15830	COG0584	glycerophosphoryl diester phosphodiesterase
BM45_RS15850	COG3291	Pkd domain containing protein
BM45_RS15860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM45_RS15910	COG0589	response to stress
BM45_RS15935	COG4221	oxidoreductase activity
BM45_RS15950	COG1113	amino acid transport
BM45_RS15960	COG2916	Histone family protein nucleoid-structuring protein H-NS
BM45_RS15980	COG2801	Transposase and inactivated derivatives
BM45_RS15985	COG2963	transposase activity
BM45_RS15990	COG0302	gtp cyclohydrolase
BM45_RS16105	COG5295	Hep Hag repeat protein
BM45_RS16120	COG3023	N-Acetylmuramoyl-L-alanine amidase
BM45_RS16145	COG5564	TIM-barrel signal transduction protein
BM45_RS16150	COG5441	Belongs to the UPF0261 family
BM45_RS16175	COG1063	alcohol dehydrogenase
BM45_RS16180	COG4948	Mandelate Racemase Muconate Lactonizing
BM45_RS16190	COG0246	Mannitol dehydrogenase
BM45_RS16195	COG2271	Major facilitator Superfamily
BM45_RS16200	COG1349	DNA-binding transcription factor activity
BM45_RS16215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BM45_RS16225	COG0583	DNA-binding transcription factor activity
BM45_RS16235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BM45_RS16240	COG1012	belongs to the aldehyde dehydrogenase family
BM45_RS16245	COG1477	protein flavinylation
BM45_RS16280	COG2814	Major facilitator Superfamily
BM45_RS16310	COG4638	Rieske (2fe-2S)
BM45_RS16335	COG1960	acyl-CoA dehydrogenase activity
BM45_RS16340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BM45_RS16385	COG5295	Hep Hag repeat protein
BM45_RS16395	COG2801	Transposase and inactivated derivatives
BM45_RS16400	COG2963	transposase activity
BM45_RS16430	COG0583	DNA-binding transcription factor activity
BM45_RS16440	COG0583	DNA-binding transcription factor activity
BM45_RS16465	COG1012	belongs to the aldehyde dehydrogenase family
BM45_RS16470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BM45_RS16475	COG0531	amino acid
BM45_RS16490	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS16510	COG1902	pentaerythritol trinitrate reductase activity
BM45_RS16525	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS16530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BM45_RS16540	COG0517	IMP dehydrogenase activity
BM45_RS16540	COG0516	GMP reductase activity
BM45_RS16545	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BM45_RS16565	COG2197	response regulator
BM45_RS16570	COG1285	pathogenesis
BM45_RS16575	COG1408	metallophosphoesterase
BM45_RS16590	COG1414	Transcriptional regulator
BM45_RS16595	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS16600	COG2146	nitrite reductase [NAD(P)H] activity
BM45_RS16630	COG1414	Transcriptional regulator
BM45_RS16635	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS16640	COG0028	Belongs to the TPP enzyme family
BM45_RS16650	COG1012	belongs to the aldehyde dehydrogenase family
BM45_RS16665	COG0477	Major facilitator Superfamily
BM45_RS16690	COG0154	amidase activity
BM45_RS16695	COG1522	sequence-specific DNA binding
BM45_RS16730	COG0492	ferredoxin-NADP+ reductase activity
BM45_RS16735	COG2801	Transposase and inactivated derivatives
BM45_RS16755	COG0596	Alpha beta hydrolase
BM45_RS16780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BM45_RS16805	COG0840	transmembrane signaling receptor activity
BM45_RS16810	COG0840	transmembrane signaling receptor activity
BM45_RS16835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BM45_RS16840	COG0596	Alpha beta hydrolase
BM45_RS16865	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS16890	COG0583	DNA-binding transcription factor activity
BM45_RS16910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BM45_RS16915	COG0601	transmembrane transport
BM45_RS16925	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BM45_RS16960	COG3209	COG3209 Rhs family protein
BM45_RS16990	COG2140	Oxalate decarboxylase
BM45_RS16995	COG1914	H( )-stimulated, divalent metal cation uptake system
BM45_RS17000	COG4682	membrane
BM45_RS17005	COG3781	membrane
BM45_RS17010	COG0243	molybdopterin cofactor binding
BM45_RS17015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BM45_RS17035	COG1404	Belongs to the peptidase S8 family
BM45_RS17060	COG2259	Doxx family
BM45_RS17085	COG4160	amino acid transport
BM45_RS17090	COG4598	ABC transporter
BM45_RS17095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BM45_RS17130	COG3275	phosphorelay sensor kinase activity
BM45_RS17135	COG2801	Transposase and inactivated derivatives
BM45_RS17140	COG2963	transposase activity
BM45_RS17145	COG3279	Response regulator of the LytR AlgR family
BM45_RS17160	COG0500	methyltransferase
BM45_RS17165	COG2207	Transcriptional regulator
BM45_RS17180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BM45_RS17185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BM45_RS17190	COG1024	Enoyl-CoA hydratase
BM45_RS17195	COG1024	Enoyl-CoA hydratase
BM45_RS17210	COG3425	synthase
BM45_RS17230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BM45_RS17230	COG2070	2-Nitropropane dioxygenase
BM45_RS17235	COG0475	glutathione-regulated potassium exporter activity
BM45_RS17235	COG0569	domain protein
BM45_RS17245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BM45_RS17245	COG0300	oxidoreductase activity
BM45_RS17245	COG3321	synthase
BM45_RS17245	COG4221	oxidoreductase activity
BM45_RS17250	COG0300	oxidoreductase activity
BM45_RS17250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BM45_RS17250	COG0300	oxidoreductase activity
BM45_RS17250	COG3321	synthase
BM45_RS17250	COG4221	oxidoreductase activity
BM45_RS17250	COG3321	synthase
BM45_RS17250	COG4221	oxidoreductase activity
BM45_RS17250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BM45_RS17260	COG4221	oxidoreductase activity
BM45_RS17260	COG3321	synthase
BM45_RS17260	COG0300	oxidoreductase activity
BM45_RS17260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BM45_RS17290	COG0583	DNA-binding transcription factor activity
BM45_RS17300	COG0387	Pfam Sodium calcium exchanger
BM45_RS17315	COG0179	Fumarylacetoacetate (FAA) hydrolase
BM45_RS17340	COG2353	YceI-like domain
BM45_RS17355	COG1595	DNA-templated transcription, initiation
BM45_RS17360	COG3712	iron ion homeostasis
BM45_RS17365	COG4774	siderophore transport
BM45_RS17370	COG1172	Belongs to the binding-protein-dependent transport system permease family
BM45_RS17375	COG1172	Belongs to the binding-protein-dependent transport system permease family
BM45_RS17380	COG1129	ABC transporter
BM45_RS17395	COG1960	acyl-CoA dehydrogenase activity
BM45_RS17400	COG2271	Major facilitator Superfamily
BM45_RS17410	COG2801	Transposase and inactivated derivatives
BM45_RS17415	COG2963	transposase activity
BM45_RS17505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM45_RS17510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM45_RS17520	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BM45_RS17535	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BM45_RS17565	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS17570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BM45_RS17570	COG4651	solute:proton antiporter activity
BM45_RS17610	COG1349	DNA-binding transcription factor activity
BM45_RS17615	COG2223	nitrite transmembrane transporter activity
BM45_RS17640	COG1063	alcohol dehydrogenase
BM45_RS17645	COG3842	ATPase activity
BM45_RS17655	COG1070	Carbohydrate kinase
BM45_RS17680	COG0243	molybdopterin cofactor binding
BM45_RS17685	COG2146	nitrite reductase [NAD(P)H] activity
BM45_RS17690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BM45_RS17710	COG3707	response regulator
BM45_RS17715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BM45_RS17715	COG1116	anion transmembrane transporter activity
BM45_RS17720	COG0302	gtp cyclohydrolase
BM45_RS17740	COG0477	Major facilitator Superfamily
BM45_RS17755	COG1794	racemase activity, acting on amino acids and derivatives
BM45_RS17760	COG0583	DNA-binding transcription factor activity
BM45_RS17780	COG2130	NADP-dependent
BM45_RS17785	COG1979	alcohol dehydrogenase
BM45_RS17820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BM45_RS17845	COG2801	Transposase and inactivated derivatives
BM45_RS17850	COG2963	transposase activity
BM45_RS17880	COG0318	PFAM AMP-dependent synthetase and ligase
BM45_RS17890	COG1739	Uncharacterized protein family UPF0029
BM45_RS17915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BM45_RS17925	COG2963	transposase activity
BM45_RS17930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BM45_RS17960	COG2274	protein secretion by the type I secretion system
BM45_RS17995	COG1201	RNA secondary structure unwinding
BM45_RS18000	COG2801	Transposase and inactivated derivatives
BM45_RS18010	COG0531	amino acid
BM45_RS18030	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BM45_RS18035	COG4122	O-methyltransferase activity
BM45_RS18040	COG2203	Gaf domain
BM45_RS18040	COG3706	GGDEF domain
BM45_RS18040	COG4251	negative regulation of phosphorylation
BM45_RS18040	COG5001	Diguanylate cyclase
BM45_RS18060	COG0583	DNA-binding transcription factor activity
BM45_RS18065	COG3485	protocatechuate 3,4-dioxygenase
BM45_RS18070	COG3485	protocatechuate 3,4-dioxygenase
BM45_RS18085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BM45_RS18090	COG0601	transmembrane transport
BM45_RS18095	COG0747	negative chemotaxis
BM45_RS18100	COG4172	Belongs to the ABC transporter superfamily
BM45_RS18105	COG1446	asparaginase
BM45_RS18115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BM45_RS18145	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BM45_RS18155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BM45_RS18160	COG0277	FAD linked oxidase domain protein
BM45_RS18210	COG2188	Transcriptional regulator
BM45_RS18215	COG2814	Major facilitator Superfamily
BM45_RS18230	COG1858	cytochrome C peroxidase
BM45_RS18235	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BM45_RS18250	COG0456	acetyltransferase
BM45_RS18260	COG2391	methyltransferase activity
BM45_RS18265	COG0640	Transcriptional regulator
BM45_RS18275	COG3038	cytochrome b561
BM45_RS18280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BM45_RS18285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BM45_RS18295	COG1045	serine acetyltransferase
BM45_RS18305	COG1505	serine-type exopeptidase activity
BM45_RS18310	COG1566	PFAM secretion protein HlyD family protein
BM45_RS18325	COG2814	Major facilitator Superfamily
BM45_RS18340	COG2801	Transposase and inactivated derivatives
BM45_RS18345	COG2963	transposase activity
BM45_RS18360	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BM45_RS18375	COG0477	Major facilitator Superfamily
BM45_RS18385	COG0784	Response regulator, receiver
BM45_RS18390	COG4251	negative regulation of phosphorylation
BM45_RS18405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BM45_RS18425	COG1278	Cold shock
BM45_RS18445	COG0446	pyridine nucleotide-disulphide oxidoreductase
BM45_RS18445	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BM45_RS18450	COG2963	transposase activity
BM45_RS18455	COG2801	Transposase and inactivated derivatives
BM45_RS18520	COG1215	transferase activity, transferring glycosyl groups
BM45_RS18530	COG0840	transmembrane signaling receptor activity
BM45_RS18540	COG0318	PFAM AMP-dependent synthetase and ligase
BM45_RS18570	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS18580	COG0628	permease
BM45_RS18590	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BM45_RS18600	COG1902	pentaerythritol trinitrate reductase activity
BM45_RS18615	COG1309	transcriptional regulator
BM45_RS18635	COG2801	Transposase and inactivated derivatives
BM45_RS18640	COG3217	Mosc domain protein beta barrel domain protein
BM45_RS18640	COG0633	Ferredoxin
BM45_RS18645	COG0642	Histidine kinase
BM45_RS18665	COG3842	ATPase activity
BM45_RS18680	COG2207	Transcriptional regulator
BM45_RS18690	COG3971	2-oxopent-4-enoate hydratase activity
BM45_RS18700	COG3384	dioxygenase
BM45_RS18705	COG1012	belongs to the aldehyde dehydrogenase family
BM45_RS18720	COG1846	Transcriptional regulator
BM45_RS18735	COG0745	RESPONSE REGULATOR receiver
BM45_RS18740	COG2205	protein histidine kinase activity
BM45_RS18770	COG2207	Transcriptional regulator
BM45_RS18810	COG1845	cytochrome c oxidase, subunit III
BM45_RS18820	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BM45_RS18830	COG0477	Major facilitator Superfamily
BM45_RS18835	COG3214	Protein conserved in bacteria
BM45_RS18850	COG2801	Transposase and inactivated derivatives
BM45_RS18855	COG2963	transposase activity
BM45_RS18910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM45_RS18935	COG0642	Histidine kinase
BM45_RS18995	COG2205	protein histidine kinase activity
BM45_RS19000	COG0745	RESPONSE REGULATOR receiver
BM45_RS19010	COG2066	Belongs to the glutaminase family
BM45_RS19020	COG2963	transposase activity
BM45_RS19025	COG2801	Transposase and inactivated derivatives
BM45_RS19040	COG2801	Transposase and inactivated derivatives
BM45_RS19045	COG2963	transposase activity
BM45_RS19055	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BM45_RS19060	COG0667	Aldo Keto reductase
BM45_RS19065	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS19080	COG0556	nucleotide-excision repair
BM45_RS19090	COG4633	Protein conserved in bacteria
BM45_RS19095	COG0672	)-iron permease
BM45_RS19105	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BM45_RS19110	COG2963	transposase activity
BM45_RS19150	COG1012	belongs to the aldehyde dehydrogenase family
BM45_RS19165	COG1176	ABC-type spermidine putrescine transport system, permease component I
BM45_RS19185	COG2271	Major facilitator Superfamily
BM45_RS19190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BM45_RS19195	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BM45_RS19205	COG3547	Transposase (IS116 IS110 IS902 family)
BM45_RS19210	COG2963	transposase activity
BM45_RS19220	COG3547	Transposase (IS116 IS110 IS902 family)
BM45_RS19245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BM45_RS19255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BM45_RS19265	COG0531	amino acid
BM45_RS19275	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BM45_RS19290	COG2259	Doxx family
BM45_RS19295	COG1620	l-lactate permease
BM45_RS19300	COG1556	Lactate utilization protein
BM45_RS19305	COG1139	Iron-sulfur cluster binding protein
BM45_RS19310	COG0247	lactate metabolic process
BM45_RS19315	COG2186	Transcriptional regulator
BM45_RS19340	COG2011	ABC-type metal ion transport system permease component
BM45_RS19345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BM45_RS19360	COG2197	response regulator
BM45_RS19395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BM45_RS19395	COG3321	synthase
BM45_RS19395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BM45_RS19395	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS19395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BM45_RS19410	COG0019	diaminopimelate decarboxylase activity
BM45_RS19415	COG0318	PFAM AMP-dependent synthetase and ligase
BM45_RS19450	COG1301	dicarboxylic acid transport
BM45_RS19465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM45_RS19470	COG0657	acetylesterase activity
BM45_RS19475	COG0583	DNA-binding transcription factor activity
BM45_RS19505	COG0709	Synthesizes selenophosphate from selenide and ATP
BM45_RS19530	COG1414	Transcriptional regulator
BM45_RS19535	COG1288	antiporter activity
BM45_RS19545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BM45_RS19575	COG0840	transmembrane signaling receptor activity
BM45_RS19585	COG0183	Belongs to the thiolase family
BM45_RS19590	COG1414	Transcriptional regulator
BM45_RS19595	COG1309	transcriptional regulator
BM45_RS19605	COG1473	amidohydrolase
BM45_RS19610	COG0583	DNA-binding transcription factor activity
BM45_RS19625	COG2755	lipolytic protein G-D-S-L family
BM45_RS19625	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BM45_RS19645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS19680	COG2963	transposase activity
BM45_RS19685	COG2801	Transposase and inactivated derivatives
BM45_RS19750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BM45_RS19765	COG2916	Histone family protein nucleoid-structuring protein H-NS
BM45_RS19800	COG4790	Type iii secretion
BM45_RS19910	COG0477	Major facilitator Superfamily
BM45_RS19940	COG1280	lysine exporter protein (LysE YggA)
BM45_RS19945	COG1522	sequence-specific DNA binding
BM45_RS19955	COG0306	phosphate transporter
BM45_RS19965	COG0318	PFAM AMP-dependent synthetase and ligase
BM45_RS19990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BM45_RS20000	COG4521	taurine ABC transporter
BM45_RS20005	COG2175	clavaminate synthase activity
BM45_RS20015	COG2194	sulfuric ester hydrolase activity
BM45_RS20020	COG1215	transferase activity, transferring glycosyl groups
BM45_RS20040	COG0457	Tetratricopeptide repeat
BM45_RS20045	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BM45_RS20050	COG1215	transferase activity, transferring glycosyl groups
BM45_RS20065	COG3550	peptidyl-serine autophosphorylation
BM45_RS20170	COG1450	Type ii and iii secretion system protein
BM45_RS20205	COG2207	Transcriptional regulator
BM45_RS20235	COG4794	Type iii secretion
BM45_RS20255	COG4789	Type iii secretion
BM45_RS20260	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BM45_RS20325	COG2801	Transposase and inactivated derivatives
BM45_RS20330	COG2963	transposase activity
BM45_RS20350	COG0028	Belongs to the TPP enzyme family
BM45_RS20355	COG0427	acetyl-CoA hydrolase
BM45_RS20360	COG2030	dehydratase
BM45_RS20370	COG0583	DNA-binding transcription factor activity
BM45_RS20390	COG2814	Major facilitator Superfamily
BM45_RS20400	COG4191	Histidine kinase
BM45_RS20430	COG3621	Patatin-like phospholipase
BM45_RS20470	COG0154	amidase activity
BM45_RS20490	COG3276	selenocysteine insertion sequence binding
BM45_RS20495	COG1921	L-seryl-tRNASec selenium transferase activity
BM45_RS20505	COG2864	formate dehydrogenase
BM45_RS20510	COG0437	4 iron, 4 sulfur cluster binding
BM45_RS20520	COG3383	formate dehydrogenase (NAD+) activity
BM45_RS20520	COG0243	molybdopterin cofactor binding
BM45_RS20530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM45_RS20535	COG1126	abc transporter atp-binding protein
BM45_RS20540	COG0765	amino acid transport
BM45_RS20545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM45_RS20550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM45_RS20560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM45_RS20570	COG3608	succinylglutamate desuccinylase aspartoacylase
BM45_RS20580	COG1295	ribonuclease BN
BM45_RS20585	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS20595	COG2755	lipolytic protein G-D-S-L family
BM45_RS20595	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BM45_RS20605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BM45_RS20620	COG0438	transferase activity, transferring glycosyl groups
BM45_RS20635	COG2755	lipolytic protein G-D-S-L family
BM45_RS20635	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BM45_RS20640	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BM45_RS20645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BM45_RS20680	COG0285	dihydrofolate synthase activity
BM45_RS20685	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BM45_RS20700	COG0133	tryptophan synthase activity
BM45_RS20705	COG0135	phosphoribosylanthranilate isomerase activity
BM45_RS20750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM45_RS20760	COG1522	sequence-specific DNA binding
BM45_RS20790	COG2801	Transposase and inactivated derivatives
BM45_RS20805	COG0372	Belongs to the citrate synthase family
BM45_RS20810	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BM45_RS20815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BM45_RS20820	COG1053	succinate dehydrogenase
BM45_RS20830	COG2009	succinate dehydrogenase
BM45_RS20835	COG2188	Transcriptional regulator
BM45_RS20860	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BM45_RS20865	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BM45_RS20865	COG3210	domain, Protein
BM45_RS20865	COG3064	Membrane
BM45_RS20870	COG2831	hemolysin activation secretion protein
BM45_RS20875	COG2963	transposase activity
BM45_RS20880	COG2801	Transposase and inactivated derivatives
BM45_RS20895	COG1176	ABC-type spermidine putrescine transport system, permease component I
BM45_RS20905	COG3842	ATPase activity
BM45_RS20920	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BM45_RS20925	COG4771	TonB-dependent receptor
BM45_RS20935	COG3038	cytochrome b561
BM45_RS20970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BM45_RS20975	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BM45_RS20990	COG2963	transposase activity
BM45_RS20995	COG2801	Transposase and inactivated derivatives
BM45_RS21135	COG0583	DNA-binding transcription factor activity
BM45_RS21155	COG0477	Major facilitator Superfamily
BM45_RS21160	COG1104	cysteine desulfurase activity
BM45_RS21175	COG0477	Major facilitator Superfamily
BM45_RS21180	COG0583	DNA-binding transcription factor activity
BM45_RS21190	COG0179	Fumarylacetoacetate (FAA) hydrolase
BM45_RS21215	COG2916	Histone family protein nucleoid-structuring protein H-NS
BM45_RS21240	COG2610	gluconate transmembrane transporter activity
BM45_RS21270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BM45_RS21275	COG0601	transmembrane transport
BM45_RS21290	COG3104	oligopeptide transport
BM45_RS21330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BM45_RS21355	COG2081	HI0933 family
BM45_RS21360	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BM45_RS21375	COG0142	geranyltranstransferase activity
BM45_RS21400	COG0412	Dienelactone hydrolase
BM45_RS21415	COG1252	NADH dehydrogenase
BM45_RS21425	COG1611	Belongs to the LOG family
BM45_RS21435	COG1683	Conserved Protein
BM45_RS21460	COG4695	Portal protein
BM45_RS21465	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BM45_RS21490	COG1846	Transcriptional regulator
BM45_RS21495	COG1764	response to oxidative stress
BM45_RS21515	COG0725	ABC transporter, periplasmic molybdate-binding protein
BM45_RS21520	COG4149	molybdate abc transporter
BM45_RS21545	COG0583	DNA-binding transcription factor activity
BM45_RS21560	COG1253	flavin adenine dinucleotide binding
BM45_RS21565	COG0352	thiamine-phosphate diphosphorylase activity
BM45_RS21570	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BM45_RS21615	COG2963	transposase activity
BM45_RS21640	COG0247	lactate metabolic process
BM45_RS21645	COG1592	Rubrerythrin
BM45_RS21650	COG3023	N-Acetylmuramoyl-L-alanine amidase
BM45_RS21655	COG4941	Belongs to the sigma-70 factor family
BM45_RS21665	COG3795	YCII-related domain
BM45_RS21670	COG3795	YCII-related domain
BM45_RS21690	COG0628	permease
BM45_RS21710	COG2130	NADP-dependent
BM45_RS21725	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS21745	COG0583	DNA-binding transcription factor activity
BM45_RS21770	COG2837	iron assimilation
BM45_RS21775	COG5265	(ABC) transporter
BM45_RS21785	COG4977	sequence-specific DNA binding
BM45_RS21810	COG0038	chloride channel
BM45_RS21845	COG0840	transmembrane signaling receptor activity
BM45_RS21850	COG0642	Histidine kinase
BM45_RS21865	COG1012	belongs to the aldehyde dehydrogenase family
BM45_RS21875	COG0025	NhaP-type Na H and K H
BM45_RS21880	COG2733	membrane
BM45_RS21895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BM45_RS21910	COG2146	nitrite reductase [NAD(P)H] activity
BM45_RS21915	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BM45_RS21920	COG4638	Rieske (2fe-2S)
BM45_RS21950	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BM45_RS21975	COG0446	pyridine nucleotide-disulphide oxidoreductase
BM45_RS21975	COG1902	pentaerythritol trinitrate reductase activity
BM45_RS21995	COG0583	DNA-binding transcription factor activity
BM45_RS22000	COG4638	Rieske (2fe-2S)
BM45_RS22005	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BM45_RS22010	COG0543	2 iron, 2 sulfur cluster binding
BM45_RS22010	COG0633	Ferredoxin
BM45_RS22015	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS22030	COG1335	isochorismatase
BM45_RS22060	COG2801	Transposase and inactivated derivatives
BM45_RS22085	COG0596	Alpha beta hydrolase
BM45_RS22150	COG2801	Transposase and inactivated derivatives
BM45_RS22155	COG2801	Transposase and inactivated derivatives
BM45_RS22205	COG0477	Major facilitator Superfamily
BM45_RS22210	COG2916	Histone family protein nucleoid-structuring protein H-NS
BM45_RS22240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BM45_RS22245	COG1595	DNA-templated transcription, initiation
BM45_RS22300	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BM45_RS22305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BM45_RS22310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BM45_RS22315	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BM45_RS22335	COG0302	gtp cyclohydrolase
BM45_RS22340	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS22345	COG1045	serine acetyltransferase
BM45_RS22370	COG2963	transposase activity
BM45_RS22375	COG2801	Transposase and inactivated derivatives
BM45_RS22395	COG0589	response to stress
BM45_RS22400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BM45_RS22405	COG0583	DNA-binding transcription factor activity
BM45_RS22420	COG1032	radical SAM domain protein
BM45_RS22460	COG0671	phosphoesterase, PA-phosphatase related
BM45_RS22470	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS22490	COG0625	glutathione transferase activity
BM45_RS22500	COG0583	DNA-binding transcription factor activity
BM45_RS22505	COG0473	3-isopropylmalate dehydrogenase activity
BM45_RS22520	COG1309	transcriptional regulator
BM45_RS22540	COG1396	sequence-specific DNA binding
BM45_RS22580	COG1192	Involved in chromosome partitioning
BM45_RS22585	COG1393	Belongs to the ArsC family
BM45_RS22595	COG1595	DNA-templated transcription, initiation
BM45_RS22630	COG1562	ergosterol biosynthetic process
BM45_RS22640	COG1657	PFAM Prenyltransferase squalene oxidase
BM45_RS22650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM45_RS22655	COG0765	amino acid transport
BM45_RS22660	COG1126	abc transporter atp-binding protein
BM45_RS22670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BM45_RS22695	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS22705	COG2072	flavoprotein involved in K transport
BM45_RS22710	COG1136	(ABC) transporter
BM45_RS22745	COG3447	MASE1 domain protein
BM45_RS22745	COG5001	Diguanylate cyclase
BM45_RS22745	COG5002	protein histidine kinase activity
BM45_RS22780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BM45_RS22800	COG0456	acetyltransferase
BM45_RS22800	COG0454	-acetyltransferase
BM45_RS22810	COG0154	amidase activity
BM45_RS22815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS22865	COG3302	dmso reductase anchor subunit
BM45_RS22870	COG0437	4 iron, 4 sulfur cluster binding
BM45_RS22875	COG0243	molybdopterin cofactor binding
BM45_RS22890	COG3246	L-lysine catabolic process to acetate
BM45_RS22895	COG2175	clavaminate synthase activity
BM45_RS22925	COG0071	Belongs to the small heat shock protein (HSP20) family
BM45_RS22935	COG2239	Acts as a magnesium transporter
BM45_RS22985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BM45_RS23020	COG0022	dehydrogenase e1 component
BM45_RS23045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BM45_RS23060	COG2091	lysine biosynthetic process via aminoadipic acid
BM45_RS23065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM45_RS23070	COG2084	Dehydrogenase
BM45_RS23080	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BM45_RS23085	COG0688	phosphatidylethanolamine metabolic process
BM45_RS23095	COG5265	(ABC) transporter
BM45_RS23105	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS23110	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BM45_RS23115	COG0859	PFAM glycosyl transferase family 9
BM45_RS23120	COG2192	nodulation
BM45_RS23145	COG2204	response regulator
BM45_RS23160	COG0784	Response regulator, receiver
BM45_RS23160	COG2198	Histidine kinase
BM45_RS23160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM45_RS23160	COG2205	protein histidine kinase activity
BM45_RS23170	COG0438	transferase activity, transferring glycosyl groups
BM45_RS23180	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS23195	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS23215	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BM45_RS23230	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BM45_RS23250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BM45_RS23310	COG2963	transposase activity
BM45_RS23315	COG0513	Belongs to the DEAD box helicase family
BM45_RS23330	COG1473	amidohydrolase
BM45_RS23335	COG0583	DNA-binding transcription factor activity
BM45_RS23375	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS23395	COG3537	Alpha-1,2-mannosidase
BM45_RS23420	COG0367	asparagine synthase
BM45_RS23450	COG2885	chlorophyll binding
BM45_RS23550	COG0583	DNA-binding transcription factor activity
BM45_RS23595	COG1984	allophanate hydrolase subunit 2
BM45_RS23610	COG0511	ligase activity, forming carbon-carbon bonds
BM45_RS23615	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BM45_RS23645	COG0840	transmembrane signaling receptor activity
BM45_RS23700	COG0535	radical SAM domain protein
BM45_RS23705	COG0840	transmembrane signaling receptor activity
BM45_RS23730	COG1285	pathogenesis
BM45_RS23755	COG2217	Heavy metal translocating P-type atpase
BM45_RS23790	COG0346	lactoylglutathione lyase activity
BM45_RS23800	COG1562	ergosterol biosynthetic process
BM45_RS23810	COG0583	DNA-binding transcription factor activity
BM45_RS23820	COG1294	oxidase, subunit
BM45_RS23825	COG1271	oxidase subunit
BM45_RS23830	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BM45_RS23845	COG2860	membrane
BM45_RS23850	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BM45_RS23860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BM45_RS23865	COG4558	Periplasmic binding protein
BM45_RS23870	COG3720	iron ion transport
BM45_RS23895	COG3842	ATPase activity
BM45_RS23900	COG1840	ABC-type Fe3 transport system, periplasmic component
BM45_RS23915	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS23925	COG0698	ribose 5-phosphate isomerase
BM45_RS23930	COG1129	ABC transporter
BM45_RS23935	COG1172	Belongs to the binding-protein-dependent transport system permease family
BM45_RS23940	COG1879	ABC-type sugar transport system periplasmic component
BM45_RS23945	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS23950	COG1063	alcohol dehydrogenase
BM45_RS23955	COG2376	Dihydroxyacetone kinase
BM45_RS24005	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BM45_RS24040	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM45_RS24050	COG2801	Transposase and inactivated derivatives
BM45_RS24060	COG2963	transposase activity
BM45_RS24065	COG3634	alkyl hydroperoxide reductase activity
BM45_RS24085	COG0778	Nitroreductase
BM45_RS24095	COG2308	Evidence 4 Homologs of previously reported genes of
BM45_RS24120	COG1305	Transglutaminase-like
BM45_RS24125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BM45_RS24140	COG4977	sequence-specific DNA binding
BM45_RS24150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BM45_RS24155	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BM45_RS24155	COG0028	Belongs to the TPP enzyme family
BM45_RS24310	COG2814	Major facilitator Superfamily
BM45_RS24330	COG1566	PFAM secretion protein HlyD family protein
BM45_RS24335	COG1621	beta-fructofuranosidase activity
BM45_RS24360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BM45_RS24375	COG1902	pentaerythritol trinitrate reductase activity
BM45_RS24375	COG0446	pyridine nucleotide-disulphide oxidoreductase
BM45_RS24380	COG2181	nitrate reductase activity
BM45_RS24380	COG0247	lactate metabolic process
BM45_RS24385	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BM45_RS24405	COG2113	Glycine betaine
BM45_RS24425	COG3119	arylsulfatase activity
BM45_RS24460	COG3246	L-lysine catabolic process to acetate
BM45_RS24465	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM45_RS24475	COG0657	acetylesterase activity
BM45_RS24490	COG2801	Transposase and inactivated derivatives
BM45_RS24495	COG0531	amino acid
BM45_RS24500	COG3384	dioxygenase
BM45_RS24510	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BM45_RS24515	COG2890	protein-(glutamine-N5) methyltransferase activity
BM45_RS24545	COG0006	proline dipeptidase activity
BM45_RS24555	COG1335	isochorismatase
BM45_RS24565	COG0488	(ABC) transporter
BM45_RS24580	COG0584	glycerophosphoryl diester phosphodiesterase
BM45_RS24610	COG0012	GTP binding
BM45_RS24625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM45_RS24630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BM45_RS24645	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BM45_RS24665	COG0512	Glutamine amidotransferase of anthranilate synthase
BM45_RS24675	COG0546	phosphoglycolate phosphatase activity
BM45_RS24680	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BM45_RS24685	COG2967	ApaG domain
BM45_RS24695	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BM45_RS24710	COG1024	Enoyl-CoA hydratase
BM45_RS24715	COG0183	Belongs to the thiolase family
BM45_RS24725	COG1024	Enoyl-CoA hydratase
BM45_RS24760	COG2801	Transposase and inactivated derivatives
BM45_RS24800	COG2801	Transposase and inactivated derivatives
BM45_RS24810	COG0798	PFAM Bile acid sodium symporter
BM45_RS24825	COG0640	Transcriptional regulator
BM45_RS24845	COG4175	Glycine betaine
BM45_RS24880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BM45_RS24885	COG3622	Belongs to the hyi family
BM45_RS24890	COG2271	Major facilitator Superfamily
BM45_RS24895	COG0235	Class ii aldolase
BM45_RS24900	COG3395	kinase activity
BM45_RS24905	COG2084	Dehydrogenase
BM45_RS24910	COG2186	Transcriptional regulator
BM45_RS24930	COG2963	transposase activity
BM45_RS24935	COG2801	Transposase and inactivated derivatives
BM45_RS24945	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS24985	COG0583	DNA-binding transcription factor activity
BM45_RS25000	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS25010	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BM45_RS25015	COG2508	Transcriptional regulator
BM45_RS25020	COG0402	S-adenosylhomocysteine deaminase activity
BM45_RS25050	COG0038	chloride channel
BM45_RS25060	COG1858	cytochrome C peroxidase
BM45_RS25065	COG3511	phospholipase C
BM45_RS25080	COG2197	response regulator
BM45_RS25135	COG1024	Enoyl-CoA hydratase
BM45_RS25140	COG1012	belongs to the aldehyde dehydrogenase family
BM45_RS25150	COG2814	Major facilitator Superfamily
BM45_RS25155	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BM45_RS25175	COG1129	ABC transporter
BM45_RS25180	COG1172	Belongs to the binding-protein-dependent transport system permease family
BM45_RS25190	COG2721	sulfolactate sulfo-lyase activity
BM45_RS25200	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS25210	COG1028	Short-chain dehydrogenase reductase Sdr
BM45_RS25220	COG2801	Transposase and inactivated derivatives
BM45_RS25225	COG2963	transposase activity
BM45_RS25250	COG5295	Hep Hag repeat protein
BM45_RS25250	COG5295	Hep Hag repeat protein
BM45_RS25255	COG2916	Histone family protein nucleoid-structuring protein H-NS
BM45_RS25290	COG1272	protein, Hemolysin III
BM45_RS25305	COG1522	sequence-specific DNA binding
BM45_RS25315	COG1448	Aminotransferase
BM45_RS25350	COG4191	Histidine kinase
BM45_RS25350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM45_RS25355	COG2201	protein-glutamate methylesterase activity
BM45_RS25365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BM45_RS25370	COG2373	Large extracellular alpha-helical protein
BM45_RS25395	COG0495	leucyl-tRNA aminoacylation
BM45_RS25400	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BM45_RS25415	COG2175	clavaminate synthase activity
BM45_RS25420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity