locus-tag	class	description
DM55_RS00020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DM55_RS00035	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DM55_RS00040	COG0789	Transcriptional regulator
DM55_RS00045	COG0477	Major facilitator Superfamily
DM55_RS00050	COG3228	Belongs to the MtfA family
DM55_RS00065	COG0534	Mate efflux family protein
DM55_RS00090	COG0542	response to heat
DM55_RS00095	COG1959	2 iron, 2 sulfur cluster binding
DM55_RS00100	COG2346	COG2346, Truncated hemoglobins
DM55_RS00105	COG0314	molybdopterin synthase activity
DM55_RS00110	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DM55_RS00130	COG0436	Aminotransferase
DM55_RS00140	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DM55_RS00145	COG2076	Multidrug Resistance protein
DM55_RS00150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DM55_RS00155	COG0463	Glycosyl transferase, family 2
DM55_RS00165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DM55_RS00165	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DM55_RS00170	COG0726	polysaccharide deacetylase
DM55_RS00175	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DM55_RS00180	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DM55_RS00185	COG0791	NLP P60 protein
DM55_RS00190	COG0306	phosphate transporter
DM55_RS00230	COG1595	DNA-templated transcription, initiation
DM55_RS00245	COG2963	transposase activity
DM55_RS00250	COG2801	Transposase and inactivated derivatives
DM55_RS00255	COG2801	Transposase and inactivated derivatives
DM55_RS00260	COG2963	transposase activity
DM55_RS00265	COG0252	asparaginase activity
DM55_RS00290	COG0438	transferase activity, transferring glycosyl groups
DM55_RS00315	COG0084	hydrolase, TatD family'
DM55_RS00320	COG1247	-acetyltransferase
DM55_RS00335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DM55_RS00340	COG0354	folic acid binding
DM55_RS00355	COG0657	acetylesterase activity
DM55_RS00360	COG2130	NADP-dependent
DM55_RS00380	COG0183	Belongs to the thiolase family
DM55_RS00385	COG1335	isochorismatase
DM55_RS00390	COG1024	Enoyl-CoA hydratase
DM55_RS00390	COG1250	3-hydroxyacyl-CoA dehydrogenase
DM55_RS00395	COG0318	PFAM AMP-dependent synthetase and ligase
DM55_RS00420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DM55_RS00430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DM55_RS00430	COG0047	phosphoribosylformylglycinamidine synthase activity
DM55_RS00440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DM55_RS00455	COG4181	ATPase activity
DM55_RS00510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DM55_RS00535	COG1929	Belongs to the glycerate kinase type-1 family
DM55_RS00540	COG1846	Transcriptional regulator
DM55_RS00545	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DM55_RS00585	COG2963	transposase activity
DM55_RS00590	COG0583	DNA-binding transcription factor activity
DM55_RS00595	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DM55_RS00600	COG4208	sulfate ABC transporter
DM55_RS00605	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DM55_RS00610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DM55_RS00650	COG0701	Predicted permease
DM55_RS00655	COG0667	Aldo Keto reductase
DM55_RS00680	COG1301	dicarboxylic acid transport
DM55_RS00705	COG2963	transposase activity
DM55_RS00750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DM55_RS00765	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DM55_RS00825	COG4266	Belongs to the allantoicase family
DM55_RS00830	COG3195	allantoin biosynthetic process
DM55_RS00830	COG3648	Uricase
DM55_RS00845	COG1953	Uracil, thiamine, allantoin
DM55_RS00860	COG1619	proteins homologs of microcin C7 resistance protein MccF
DM55_RS00915	COG0697	spore germination
DM55_RS00925	COG2867	negative regulation of translational initiation
DM55_RS00935	COG0330	HflC and HflK could
DM55_RS00975	COG2963	transposase activity
DM55_RS00980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DM55_RS01020	COG0750	zinc metalloprotease
DM55_RS01035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DM55_RS01065	COG0024	Methionine aminopeptidase
DM55_RS01075	COG1187	pseudouridine synthase activity
DM55_RS01080	COG0242	peptide deformylase activity
DM55_RS01120	COG1393	Belongs to the ArsC family
DM55_RS01130	COG2890	protein-(glutamine-N5) methyltransferase activity
DM55_RS01145	COG0386	Belongs to the glutathione peroxidase family
DM55_RS01150	COG0488	(ABC) transporter
DM55_RS01170	COG0477	Major facilitator Superfamily
DM55_RS01175	COG0351	phosphomethylpyrimidine kinase
DM55_RS01185	COG1573	uracil-dna glycosylase
DM55_RS01195	COG1214	PFAM Peptidase M22, glycoprotease
DM55_RS01205	COG0513	Belongs to the DEAD box helicase family
DM55_RS01215	COG2963	transposase activity
DM55_RS01230	COG2224	Isocitrate lyase
DM55_RS01240	COG0583	DNA-binding transcription factor activity
DM55_RS01250	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DM55_RS01300	COG1752	Esterase of the alpha-beta hydrolase superfamily
DM55_RS01305	COG0791	NLP P60 protein
DM55_RS01310	COG4172	Belongs to the ABC transporter superfamily
DM55_RS01315	COG4239	(ABC) transporter, permease
DM55_RS01320	COG4174	ABC transporter (Permease)
DM55_RS01325	COG4166	transmembrane transport
DM55_RS01345	COG0243	molybdopterin cofactor binding
DM55_RS01370	COG0024	Methionine aminopeptidase
DM55_RS01385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DM55_RS01405	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DM55_RS01420	COG3958	Transketolase
DM55_RS01425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DM55_RS01445	COG2175	clavaminate synthase activity
DM55_RS01475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DM55_RS01480	COG2895	sulfate adenylyltransferase (ATP) activity
DM55_RS01480	COG0529	Catalyzes the synthesis of activated sulfate
DM55_RS01485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM55_RS01490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM55_RS01525	COG0527	aspartate kinase activity
DM55_RS01530	COG0037	tRNA processing
DM55_RS01555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DM55_RS01565	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DM55_RS01570	COG1045	serine acetyltransferase
DM55_RS01580	COG0483	inositol monophosphate 1-phosphatase activity
DM55_RS01610	COG2850	peptidyl-arginine hydroxylation
DM55_RS01620	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DM55_RS01625	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DM55_RS01630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DM55_RS01640	COG0180	Tryptophanyl-tRNA synthetase
DM55_RS01645	COG1994	Peptidase M50
DM55_RS01650	COG0009	L-threonylcarbamoyladenylate synthase
DM55_RS01655	COG0613	PHP domain protein
DM55_RS01660	COG0596	Alpha beta hydrolase
DM55_RS01665	COG2833	Protein of unknown function (DUF455)
DM55_RS01675	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DM55_RS01685	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DM55_RS01710	COG0658	competence protein
DM55_RS01710	COG2333	competence protein COMEC
DM55_RS01715	COG0084	hydrolase, TatD family'
DM55_RS01720	COG1136	(ABC) transporter
DM55_RS01735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DM55_RS01755	COG2975	iron-sulfur cluster assembly
DM55_RS01775	COG0316	Belongs to the HesB IscA family
DM55_RS01780	COG0822	iron-sulfur transferase activity
DM55_RS01785	COG1104	cysteine desulfurase activity
DM55_RS01795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DM55_RS01815	COG1414	Transcriptional regulator
DM55_RS01825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DM55_RS01830	COG1047	Peptidyl-prolyl cis-trans
DM55_RS01850	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DM55_RS01870	COG3264	Mechanosensitive ion channel
DM55_RS01870	COG1511	domain protein
DM55_RS01875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DM55_RS01875	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DM55_RS01880	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DM55_RS01885	COG0196	riboflavin kinase activity
DM55_RS01890	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DM55_RS01920	COG2963	transposase activity
DM55_RS01925	COG2801	Transposase and inactivated derivatives
DM55_RS01930	COG1113	amino acid transport
DM55_RS01935	COG0542	response to heat
DM55_RS01945	COG2801	Transposase and inactivated derivatives
DM55_RS01950	COG2963	transposase activity
DM55_RS01955	COG1278	Cold shock
DM55_RS01980	COG1663	tetraacyldisaccharide 4'-kinase activity
DM55_RS01985	COG1570	exodeoxyribonuclease VII activity
DM55_RS01990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DM55_RS02000	COG2963	transposase activity
DM55_RS02005	COG2801	Transposase and inactivated derivatives
DM55_RS02045	COG0592	DNA-directed DNA polymerase activity
DM55_RS02055	COG2963	transposase activity
DM55_RS02060	COG2801	Transposase and inactivated derivatives
DM55_RS02065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DM55_RS02130	COG0235	Class ii aldolase
DM55_RS02135	COG5001	Diguanylate cyclase
DM55_RS02135	COG5002	protein histidine kinase activity
DM55_RS02170	COG2204	response regulator
DM55_RS02190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DM55_RS02200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DM55_RS02215	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DM55_RS02220	COG1596	polysaccharide export
DM55_RS02240	COG1064	alcohol dehydrogenase
DM55_RS02250	COG2207	Transcriptional regulator
DM55_RS02260	COG2814	Major facilitator Superfamily
DM55_RS02275	COG1309	transcriptional regulator
DM55_RS02300	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DM55_RS02320	COG0523	cobalamin synthesis protein
DM55_RS02330	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DM55_RS02345	COG1560	Kdo2-lipid A biosynthetic process
DM55_RS02370	COG0667	Aldo Keto reductase
DM55_RS02385	COG2814	Major facilitator Superfamily
DM55_RS02395	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DM55_RS02470	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DM55_RS02485	COG0531	amino acid
DM55_RS02510	COG1280	lysine exporter protein (LysE YggA)
DM55_RS02515	COG3568	Endonuclease Exonuclease Phosphatase
DM55_RS02535	COG0579	oxidoreductase
DM55_RS02550	COG0747	negative chemotaxis
DM55_RS02555	COG0601	transmembrane transport
DM55_RS02565	COG0444	Belongs to the ABC transporter superfamily
DM55_RS02570	COG4608	Belongs to the ABC transporter superfamily
DM55_RS02600	COG1984	allophanate hydrolase subunit 2
DM55_RS02605	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DM55_RS02615	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DM55_RS02620	COG0741	lytic transglycosylase activity
DM55_RS02650	COG2747	anti-sigma28 factor FlgM
DM55_RS02665	COG1815	bacterial-type flagellum-dependent cell motility
DM55_RS02670	COG1558	bacterial-type flagellum-dependent cell motility
DM55_RS02675	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DM55_RS02680	COG1749	Flagellar hook protein flgE
DM55_RS02695	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DM55_RS02700	COG1706	bacterial-type flagellum-dependent cell motility
DM55_RS02710	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DM55_RS02720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DM55_RS02725	COG2233	PERMEase
DM55_RS02730	COG0583	DNA-binding transcription factor activity
DM55_RS02750	COG2824	Alkylphosphonate utilization operon protein PhnA
DM55_RS02760	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DM55_RS02785	COG2801	Transposase and inactivated derivatives
DM55_RS02790	COG2963	transposase activity
DM55_RS02860	COG1704	LemA family
DM55_RS02865	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DM55_RS02885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM55_RS02890	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM55_RS02910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DM55_RS02960	COG1609	Transcriptional regulator
DM55_RS02965	COG0840	transmembrane signaling receptor activity
DM55_RS02980	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DM55_RS02985	COG2963	transposase activity
DM55_RS02990	COG2801	Transposase and inactivated derivatives
DM55_RS03005	COG1785	Belongs to the alkaline phosphatase family
DM55_RS03050	COG3012	SEC-C Motif Domain Protein
DM55_RS03060	COG0183	Belongs to the thiolase family
DM55_RS03065	COG0288	reversible hydration of carbon dioxide
DM55_RS03080	COG0488	(ABC) transporter
DM55_RS03085	COG0747	negative chemotaxis
DM55_RS03095	COG1028	Short-chain dehydrogenase reductase Sdr
DM55_RS03100	COG4221	oxidoreductase activity
DM55_RS03105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DM55_RS03140	COG0418	dihydroorotase activity
DM55_RS03145	COG0121	glutamine amidotransferase
DM55_RS03175	COG1126	abc transporter atp-binding protein
DM55_RS03180	COG0765	amino acid transport
DM55_RS03185	COG0765	amino acid transport
DM55_RS03190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DM55_RS03195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DM55_RS03200	COG0583	DNA-binding transcription factor activity
DM55_RS03205	COG2223	nitrite transmembrane transporter activity
DM55_RS03225	COG0800	Aldolase
DM55_RS03235	COG1737	Transcriptional regulator
DM55_RS03240	COG1981	membrane
DM55_RS03245	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DM55_RS03250	COG1466	dna polymerase III delta subunit
DM55_RS03280	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DM55_RS03285	COG0735	belongs to the Fur family
DM55_RS03295	COG4266	Belongs to the allantoicase family
DM55_RS03300	COG1301	dicarboxylic acid transport
DM55_RS03310	COG0583	DNA-binding transcription factor activity
DM55_RS03325	COG2814	Major facilitator Superfamily
DM55_RS03330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DM55_RS03335	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DM55_RS03340	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DM55_RS03350	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DM55_RS03380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DM55_RS03385	COG1546	Belongs to the CinA family
DM55_RS03390	COG0284	orotidine-5'-phosphate decarboxylase activity
DM55_RS03400	COG1028	Short-chain dehydrogenase reductase Sdr
DM55_RS03405	COG1172	Belongs to the binding-protein-dependent transport system permease family
DM55_RS03410	COG1129	ABC transporter
DM55_RS03420	COG1028	Short-chain dehydrogenase reductase Sdr
DM55_RS03430	COG3734	2-keto-3-deoxy-galactonokinase
DM55_RS03435	COG1414	Transcriptional regulator
DM55_RS03450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DM55_RS03455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DM55_RS03460	COG0557	exoribonuclease II activity
DM55_RS03465	COG3150	esterase
DM55_RS03470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DM55_RS03480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DM55_RS03485	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DM55_RS03490	COG0511	ligase activity, forming carbon-carbon bonds
DM55_RS03495	COG0439	Biotin carboxylase
DM55_RS03510	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DM55_RS03515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DM55_RS03555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DM55_RS03560	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DM55_RS03565	COG2095	MarC family integral membrane protein
DM55_RS03605	COG0142	geranyltranstransferase activity
DM55_RS03620	COG2801	Transposase and inactivated derivatives
DM55_RS03625	COG2963	transposase activity
DM55_RS03630	COG4536	flavin adenine dinucleotide binding
DM55_RS03635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DM55_RS03645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DM55_RS03660	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DM55_RS03665	COG0494	nUDIX hydrolase
DM55_RS03675	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DM55_RS03700	COG0678	peroxiredoxin activity
DM55_RS03715	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DM55_RS03750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DM55_RS03755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DM55_RS03765	COG3116	cell division
DM55_RS03785	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DM55_RS03825	COG1024	Enoyl-CoA hydratase
DM55_RS03850	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DM55_RS03860	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DM55_RS03875	COG0737	Belongs to the 5'-nucleotidase family
DM55_RS03880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DM55_RS03885	COG1127	ABC transporter
DM55_RS03915	COG1686	Belongs to the peptidase S11 family
DM55_RS03925	COG2921	Belongs to the UPF0250 family
DM55_RS03930	COG0583	DNA-binding transcription factor activity
DM55_RS03960	COG2963	transposase activity
DM55_RS03990	COG0583	DNA-binding transcription factor activity
DM55_RS03995	COG1024	Enoyl-CoA hydratase
DM55_RS03995	COG1250	3-hydroxyacyl-CoA dehydrogenase
DM55_RS04000	COG1960	acyl-CoA dehydrogenase activity
DM55_RS04005	COG1960	acyl-CoA dehydrogenase activity
DM55_RS04010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DM55_RS04020	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DM55_RS04040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DM55_RS04070	COG2960	long-chain fatty acid transporting porin activity
DM55_RS04080	COG0004	ammonium transporteR
DM55_RS04095	COG0189	ligase activity
DM55_RS04105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DM55_RS04110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DM55_RS04115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DM55_RS04120	COG0793	Belongs to the peptidase S41A family
DM55_RS04130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DM55_RS04150	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DM55_RS04160	COG1040	competence protein
DM55_RS04165	COG2226	methyltransferase
DM55_RS04180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DM55_RS04190	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DM55_RS04220	COG1612	heme a metabolic process
DM55_RS04230	COG1999	signal sequence binding
DM55_RS04240	COG0840	transmembrane signaling receptor activity
DM55_RS04255	COG0443	Heat shock 70 kDa protein
DM55_RS04300	COG0308	aminopeptidase N
DM55_RS04385	COG2801	Transposase and inactivated derivatives
DM55_RS04390	COG2963	transposase activity
DM55_RS04410	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DM55_RS04415	COG1950	PFAM Membrane protein of
DM55_RS04440	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DM55_RS04445	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DM55_RS04465	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DM55_RS04470	COG0745	RESPONSE REGULATOR receiver
DM55_RS04475	COG2201	protein-glutamate methylesterase activity
DM55_RS04485	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DM55_RS04505	COG2201	protein-glutamate methylesterase activity
DM55_RS04510	COG1360	Flagellar Motor Protein
DM55_RS04530	COG0438	transferase activity, transferring glycosyl groups
DM55_RS04540	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DM55_RS04545	COG0561	phosphatase activity
DM55_RS04555	COG0519	Catalyzes the synthesis of GMP from XMP
DM55_RS04590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DM55_RS04605	COG1028	Short-chain dehydrogenase reductase Sdr
DM55_RS04630	COG1280	lysine exporter protein (LysE YggA)
DM55_RS04660	COG2267	carboxylic ester hydrolase activity
DM55_RS04680	COG3397	chitin binding
DM55_RS04690	COG2963	transposase activity
DM55_RS04695	COG2801	Transposase and inactivated derivatives
DM55_RS04725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DM55_RS04730	COG1522	sequence-specific DNA binding
DM55_RS04740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DM55_RS04780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DM55_RS04780	COG0519	Catalyzes the synthesis of GMP from XMP
DM55_RS04785	COG1902	pentaerythritol trinitrate reductase activity
DM55_RS04800	COG0642	Histidine kinase
DM55_RS04820	COG3186	Phenylalanine-4-hydroxylase
DM55_RS04825	COG1522	sequence-specific DNA binding
DM55_RS04835	COG0583	DNA-binding transcription factor activity
DM55_RS04845	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DM55_RS04865	COG0559	Belongs to the binding-protein-dependent transport system permease family
DM55_RS04910	COG1192	Involved in chromosome partitioning
DM55_RS04915	COG1475	DNA binding
DM55_RS04920	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DM55_RS04930	COG0356	it plays a direct role in the translocation of protons across the membrane
DM55_RS04970	COG0318	PFAM AMP-dependent synthetase and ligase
DM55_RS04975	COG1832	CoA-binding protein
DM55_RS04990	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DM55_RS05000	COG0506	proline dehydrogenase activity
DM55_RS05000	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DM55_RS05000	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DM55_RS05015	COG1960	acyl-CoA dehydrogenase activity
DM55_RS05025	COG0436	Aminotransferase
DM55_RS05045	COG0277	FAD linked oxidase domain protein
DM55_RS05055	COG0789	Transcriptional regulator
DM55_RS05075	COG0668	transmembrane transport
DM55_RS05095	COG0531	amino acid
DM55_RS05120	COG1294	oxidase, subunit
DM55_RS05140	COG1263	PTS System
DM55_RS05140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DM55_RS05140	COG2190	(PTS) system
DM55_RS05145	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DM55_RS05145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DM55_RS05150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DM55_RS05155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DM55_RS05160	COG2188	Transcriptional regulator
DM55_RS05165	COG0583	DNA-binding transcription factor activity
DM55_RS05220	COG1960	acyl-CoA dehydrogenase activity
DM55_RS05230	COG2226	methyltransferase
DM55_RS05265	COG2814	Major facilitator Superfamily
DM55_RS05275	COG0587	DNA-directed DNA polymerase activity
DM55_RS05290	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DM55_RS05310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DM55_RS05315	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DM55_RS05325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DM55_RS05335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DM55_RS05340	COG0243	molybdopterin cofactor binding
DM55_RS05350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DM55_RS05360	COG0625	glutathione transferase activity
DM55_RS05370	COG0742	ribosomal rna small subunit methyltransferase
DM55_RS05380	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DM55_RS05385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DM55_RS05400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DM55_RS05415	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DM55_RS05430	COG1194	a g-specific adenine glycosylase
DM55_RS05455	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DM55_RS05460	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DM55_RS05465	COG1137	ATPase activity
DM55_RS05480	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DM55_RS05500	COG1280	lysine exporter protein (LysE YggA)
DM55_RS05525	COG2814	Major facilitator Superfamily
DM55_RS05530	COG0629	single-stranded DNA binding
DM55_RS05535	COG2963	transposase activity
DM55_RS05540	COG2801	Transposase and inactivated derivatives
DM55_RS05545	COG1113	amino acid transport
DM55_RS05560	COG2823	Periplasmic or secreted lipoprotein
DM55_RS05565	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DM55_RS05590	COG4303	Ethanolamine ammonia lyase large subunit
DM55_RS05595	COG4302	ethanolamine ammonia-lyase activity
DM55_RS05605	COG1012	belongs to the aldehyde dehydrogenase family
DM55_RS05630	COG1760	l-serine dehydratase
DM55_RS05645	COG0509	glycine decarboxylation via glycine cleavage system
DM55_RS05660	COG0673	inositol 2-dehydrogenase activity
DM55_RS05675	COG0210	DNA helicase
DM55_RS05680	COG3245	cytochrome
DM55_RS05690	COG0582	viral genome integration into host DNA
DM55_RS05700	COG2963	transposase activity
DM55_RS05705	COG1278	Cold shock
DM55_RS05715	COG0523	cobalamin synthesis protein
DM55_RS05735	COG1459	type II secretion system
DM55_RS05750	COG2165	general secretion pathway protein
DM55_RS05795	COG1846	Transcriptional regulator
DM55_RS05805	COG0583	DNA-binding transcription factor activity
DM55_RS05815	COG1346	cytolysis
DM55_RS05835	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DM55_RS05850	COG2963	transposase activity
DM55_RS05855	COG2801	Transposase and inactivated derivatives
DM55_RS05875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DM55_RS05880	COG1250	3-hydroxyacyl-CoA dehydrogenase
DM55_RS05880	COG1024	Enoyl-CoA hydratase
DM55_RS05885	COG0183	Belongs to the thiolase family
DM55_RS05890	COG1960	acyl-CoA dehydrogenase activity
DM55_RS05915	COG1695	Transcriptional regulator
DM55_RS05975	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DM55_RS05995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DM55_RS06010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DM55_RS06020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DM55_RS06030	COG4106	trans-aconitate 2-methyltransferase activity
DM55_RS06030	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DM55_RS06035	COG0789	Transcriptional regulator
DM55_RS06045	COG1987	bacterial-type flagellum assembly
DM55_RS06055	COG2801	Transposase and inactivated derivatives
DM55_RS06060	COG2963	transposase activity
DM55_RS06075	COG2969	positive regulation of protein catabolic process
DM55_RS06080	COG0625	glutathione transferase activity
DM55_RS06085	COG2857	Cytochrome c1
DM55_RS06090	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DM55_RS06095	COG0723	plastoquinol--plastocyanin reductase activity
DM55_RS06100	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DM55_RS06105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DM55_RS06115	COG0805	protein transport
DM55_RS06120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DM55_RS06165	COG2095	MarC family integral membrane protein
DM55_RS06175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DM55_RS06180	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DM55_RS06190	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DM55_RS06200	COG0842	Transport permease protein
DM55_RS06205	COG1131	(ABC) transporter
DM55_RS06225	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DM55_RS06230	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DM55_RS06235	COG1127	ABC transporter
DM55_RS06260	COG4178	(ABC) transporter
DM55_RS06270	COG1115	amino acid carrier protein
DM55_RS06280	COG0067	glutamate synthase
DM55_RS06280	COG0069	glutamate synthase activity
DM55_RS06280	COG0070	glutamate synthase
DM55_RS06295	COG0584	glycerophosphoryl diester phosphodiesterase
DM55_RS06300	COG3842	ATPase activity
DM55_RS06305	COG0395	ABC-type sugar transport system, permease component
DM55_RS06310	COG1175	transmembrane transport
DM55_RS06320	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DM55_RS06380	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DM55_RS06385	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DM55_RS06390	COG2801	Transposase and inactivated derivatives
DM55_RS06395	COG2963	transposase activity
DM55_RS06425	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DM55_RS06470	COG0514	ATP-dependent DNA helicase (RecQ)
DM55_RS06600	COG0201	protein transport
DM55_RS06645	COG4232	protein-disulfide reductase activity
DM55_RS06665	COG1333	cytochrome c biogenesis protein
DM55_RS06670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DM55_RS06675	COG2963	transposase activity
DM55_RS06680	COG2801	Transposase and inactivated derivatives
DM55_RS06690	COG3047	cAMP biosynthetic process
DM55_RS06705	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DM55_RS06715	COG1881	PFAM PEBP family protein
DM55_RS06720	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DM55_RS06725	COG0280	phosphate acetyltransferase
DM55_RS06725	COG0281	malic enzyme
DM55_RS06750	COG2963	transposase activity
DM55_RS06785	COG3396	Phenylacetate-CoA oxygenase
DM55_RS06790	COG3460	Phenylacetate-CoA oxygenase
DM55_RS06795	COG3396	Phenylacetate-CoA oxygenase
DM55_RS06800	COG2151	metal-sulfur cluster biosynthetic enzyme
DM55_RS06805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DM55_RS06825	COG1522	sequence-specific DNA binding
DM55_RS06840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DM55_RS06840	COG1017	nitric oxide dioxygenase activity
DM55_RS06845	COG2096	Adenosyltransferase
DM55_RS06850	COG0277	FAD linked oxidase domain protein
DM55_RS06855	COG0277	FAD linked oxidase domain protein
DM55_RS06860	COG0277	FAD linked oxidase domain protein
DM55_RS06865	COG0247	lactate metabolic process
DM55_RS06880	COG3639	organic phosphonate transmembrane transporter activity
DM55_RS06890	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DM55_RS06895	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DM55_RS06900	COG3454	Phosphonate metabolism
DM55_RS06905	COG4778	phosphonate C-P lyase system protein PhnL
DM55_RS06910	COG4107	phosphonate C-P lyase system protein PhnK
DM55_RS06915	COG3627	carbon phosphorus lyase activity
DM55_RS06920	COG3626	phosphonate metabolism
DM55_RS06930	COG3624	Phosphonate C-P lyase system protein PhnG
DM55_RS06935	COG2188	Transcriptional regulator
DM55_RS06940	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DM55_RS06965	COG0783	Belongs to the Dps family
DM55_RS06985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DM55_RS06995	COG0343	queuine tRNA-ribosyltransferase activity
DM55_RS07000	COG1862	Preprotein translocase
DM55_RS07005	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DM55_RS07010	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DM55_RS07020	COG2353	YceI-like domain
DM55_RS07025	COG2353	YceI-like domain
DM55_RS07040	COG2995	paraquat-inducible protein a
DM55_RS07045	COG3008	intermembrane lipid transfer
DM55_RS07045	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DM55_RS07115	COG0069	glutamate synthase activity
DM55_RS07120	COG0625	glutathione transferase activity
DM55_RS07125	COG0006	proline dipeptidase activity
DM55_RS07130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DM55_RS07135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DM55_RS07140	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DM55_RS07180	COG0588	phosphoglycerate mutase activity
DM55_RS07190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DM55_RS07200	COG0625	glutathione transferase activity
DM55_RS07205	COG0625	glutathione transferase activity
DM55_RS07210	COG1917	Cupin 2, conserved barrel domain protein
DM55_RS07210	COG4977	sequence-specific DNA binding
DM55_RS07235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DM55_RS07240	COG0312	modulator of DNA gyrase
DM55_RS07245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DM55_RS07250	COG3164	Protein of unknown function
DM55_RS07255	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DM55_RS07260	COG0497	DNA recombination
DM55_RS07305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DM55_RS07315	COG1428	Deoxynucleoside kinase
DM55_RS07320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DM55_RS07325	COG0617	tRNA 3'-terminal CCA addition
DM55_RS07335	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DM55_RS07355	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DM55_RS07360	COG0586	Pfam SNARE associated Golgi protein
DM55_RS07460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DM55_RS07475	COG1368	sulfuric ester hydrolase activity
DM55_RS07480	COG1028	Short-chain dehydrogenase reductase Sdr
DM55_RS07480	COG3321	synthase
DM55_RS07480	COG0604	alcohol dehydrogenase
DM55_RS07485	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DM55_RS07490	COG0156	8-amino-7-oxononanoate synthase activity
DM55_RS07505	COG2963	transposase activity
DM55_RS07510	COG2801	Transposase and inactivated derivatives
DM55_RS07520	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DM55_RS07530	COG0656	L-ascorbic acid biosynthetic process
DM55_RS07535	COG2188	Transcriptional regulator
DM55_RS07555	COG2814	Major facilitator Superfamily
DM55_RS07595	COG2963	transposase activity
DM55_RS07610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DM55_RS07610	COG2169	Transcriptional regulator
DM55_RS07625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DM55_RS07645	COG0583	DNA-binding transcription factor activity
DM55_RS07660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DM55_RS07670	COG4695	Portal protein
DM55_RS07685	COG2801	Transposase and inactivated derivatives
DM55_RS07690	COG2963	transposase activity
DM55_RS07720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DM55_RS07725	COG0583	DNA-binding transcription factor activity
DM55_RS07740	COG0758	DNA mediated transformation
DM55_RS07745	COG2801	Transposase and inactivated derivatives
DM55_RS07750	COG0758	DNA mediated transformation
DM55_RS07755	COG0242	peptide deformylase activity
DM55_RS07760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DM55_RS07775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DM55_RS07775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DM55_RS07785	COG5000	phosphorelay sensor kinase activity
DM55_RS07790	COG2204	response regulator
DM55_RS07805	COG0602	queuosine metabolic process
DM55_RS07810	COG0720	synthase
DM55_RS07825	COG0772	Belongs to the SEDS family
DM55_RS07830	COG0768	penicillin binding
DM55_RS07845	COG1077	Cell shape determining protein MreB Mrl
DM55_RS07865	COG2326	polyphosphate kinase activity
DM55_RS07870	COG0708	Exodeoxyribonuclease III
DM55_RS07895	COG0477	Major facilitator Superfamily
DM55_RS07920	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DM55_RS07930	COG0251	oxidation-reduction process
DM55_RS07940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DM55_RS08005	COG0494	nUDIX hydrolase
DM55_RS08020	COG1960	acyl-CoA dehydrogenase activity
DM55_RS08025	COG1250	3-hydroxyacyl-CoA dehydrogenase
DM55_RS08025	COG1024	Enoyl-CoA hydratase
DM55_RS08030	COG0183	Belongs to the thiolase family
DM55_RS08035	COG1024	Enoyl-CoA hydratase
DM55_RS08040	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DM55_RS08055	COG5265	(ABC) transporter
DM55_RS08065	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DM55_RS08080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DM55_RS08085	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DM55_RS08110	COG0204	Acyl-transferase
DM55_RS08115	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DM55_RS08120	COG0751	glycine-tRNA ligase activity
DM55_RS08125	COG0752	glycyl-tRNA synthetase alpha subunit
DM55_RS08130	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DM55_RS08140	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DM55_RS08150	COG1702	phosphate starvation-inducible protein PhoH
DM55_RS08160	COG0583	DNA-binding transcription factor activity
DM55_RS08165	COG2814	Major facilitator Superfamily
DM55_RS08170	COG1396	sequence-specific DNA binding
DM55_RS08180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DM55_RS08195	COG0367	asparagine synthase
DM55_RS08200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DM55_RS08205	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DM55_RS08215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DM55_RS08220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DM55_RS08260	COG0513	Belongs to the DEAD box helicase family
DM55_RS08280	COG4948	Mandelate Racemase Muconate Lactonizing
DM55_RS08320	COG0840	transmembrane signaling receptor activity
DM55_RS08345	COG3307	-O-antigen
DM55_RS08350	COG4969	Belongs to the N-Me-Phe pilin family
DM55_RS08355	COG0861	Integral membrane protein TerC family
DM55_RS08360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DM55_RS08375	COG2137	regulation of response to DNA damage stimulus
DM55_RS08380	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DM55_RS08410	COG2801	Transposase and inactivated derivatives
DM55_RS08415	COG2963	transposase activity
DM55_RS08425	COG4783	chaperone-mediated protein folding
DM55_RS08435	COG0429	hydrolase of the alpha beta-hydrolase fold
DM55_RS08445	COG0859	PFAM glycosyl transferase family 9
DM55_RS08470	COG0126	phosphoglycerate kinase activity
DM55_RS08475	COG0469	pyruvate kinase activity
DM55_RS08485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DM55_RS08490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DM55_RS08495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DM55_RS08500	COG0009	L-threonylcarbamoyladenylate synthase
DM55_RS08530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DM55_RS08555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM55_RS08560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM55_RS08580	COG2801	Transposase and inactivated derivatives
DM55_RS08585	COG2963	transposase activity
DM55_RS08590	COG2233	PERMEase
DM55_RS08595	COG1070	Carbohydrate kinase
DM55_RS08610	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DM55_RS08615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DM55_RS08620	COG1121	(ABC) transporter
DM55_RS08630	COG0735	belongs to the Fur family
DM55_RS08640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DM55_RS08655	COG1175	transmembrane transport
DM55_RS08665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DM55_RS08670	COG3842	ATPase activity
DM55_RS08680	COG0583	DNA-binding transcription factor activity
DM55_RS08695	COG2390	Transcriptional regulator
DM55_RS08700	COG1070	Carbohydrate kinase
DM55_RS08705	COG0246	Mannitol dehydrogenase
DM55_RS08710	COG0583	DNA-binding transcription factor activity
DM55_RS08720	COG1012	belongs to the aldehyde dehydrogenase family
DM55_RS08725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DM55_RS08735	COG2271	Major facilitator Superfamily
DM55_RS08755	COG1522	sequence-specific DNA binding
DM55_RS08760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DM55_RS08770	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DM55_RS08785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DM55_RS08795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DM55_RS08810	COG1741	Belongs to the pirin family
DM55_RS08820	COG0860	N-Acetylmuramoyl-L-alanine amidase
DM55_RS08825	COG0802	atpase or kinase
DM55_RS08830	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DM55_RS08840	COG4974	Belongs to the 'phage' integrase family
DM55_RS08845	COG0318	PFAM AMP-dependent synthetase and ligase
DM55_RS08850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DM55_RS08855	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DM55_RS08865	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DM55_RS08870	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DM55_RS08885	COG0728	peptidoglycan biosynthetic process
DM55_RS08920	COG2801	Transposase and inactivated derivatives
DM55_RS08930	COG0582	viral genome integration into host DNA
DM55_RS08935	COG2801	Transposase and inactivated derivatives
DM55_RS08940	COG2801	Transposase and inactivated derivatives
DM55_RS08950	COG2963	transposase activity
DM55_RS08975	COG4772	TonB-dependent receptor
DM55_RS09025	COG0583	DNA-binding transcription factor activity
DM55_RS09035	COG0308	aminopeptidase N
DM55_RS09045	COG2119	membrane
DM55_RS09050	COG0402	S-adenosylhomocysteine deaminase activity
DM55_RS09055	COG2252	PERMEase
DM55_RS09060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DM55_RS09075	COG0154	amidase activity
DM55_RS09080	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DM55_RS09105	COG3383	formate dehydrogenase (NAD+) activity
DM55_RS09120	COG1910	domain protein
DM55_RS09130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DM55_RS09135	COG2801	Transposase and inactivated derivatives
DM55_RS09140	COG2963	transposase activity
DM55_RS09145	COG0546	phosphoglycolate phosphatase activity
DM55_RS09170	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DM55_RS09175	COG0077	Prephenate dehydratase
DM55_RS09175	COG1605	Chorismate mutase
DM55_RS09180	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DM55_RS09210	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DM55_RS09220	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DM55_RS09245	COG2951	lytic endotransglycosylase activity
DM55_RS09250	COG0123	including yeast histone deacetylase and acetoin utilization protein
DM55_RS09255	COG2267	carboxylic ester hydrolase activity
DM55_RS09265	COG2011	ABC-type metal ion transport system permease component
DM55_RS09345	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DM55_RS09360	COG0501	Belongs to the peptidase M48B family
DM55_RS09370	COG0521	Mo-molybdopterin cofactor biosynthetic process
DM55_RS09375	COG3028	Belongs to the UPF0307 family
DM55_RS09380	COG0312	modulator of DNA gyrase
DM55_RS09390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DM55_RS09395	COG2204	response regulator
DM55_RS09425	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DM55_RS09440	COG0640	Transcriptional regulator
DM55_RS09455	COG0114	fumarate hydratase activity
DM55_RS09465	COG2801	Transposase and inactivated derivatives
DM55_RS09470	COG2963	transposase activity
DM55_RS09475	COG0534	Mate efflux family protein
DM55_RS09480	COG2501	S4 domain
DM55_RS09495	COG3045	CreA protein
DM55_RS09510	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DM55_RS09515	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DM55_RS09535	COG1322	Protein conserved in bacteria
DM55_RS09550	COG0303	'Molybdopterin
DM55_RS09560	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DM55_RS09565	COG1530	ribonuclease E activity
DM55_RS09600	COG1399	metal-binding, possibly nucleic acid-binding protein
DM55_RS09635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DM55_RS09655	COG3026	antisigma factor binding
DM55_RS09660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DM55_RS09675	COG0681	Belongs to the peptidase S26 family
DM55_RS09680	COG0571	ribonuclease III activity
DM55_RS09685	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DM55_RS09690	COG1381	Involved in DNA repair and RecF pathway recombination
DM55_RS09695	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DM55_RS09710	COG2204	response regulator
DM55_RS09730	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DM55_RS09755	COG1956	GAF domain-containing protein
DM55_RS09760	COG0583	DNA-binding transcription factor activity
DM55_RS09770	COG2153	protein acetylation
DM55_RS09785	COG1999	signal sequence binding
DM55_RS09795	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DM55_RS09800	COG1132	(ABC) transporter
DM55_RS09805	COG0438	transferase activity, transferring glycosyl groups
DM55_RS09820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DM55_RS09825	COG0683	leucine binding
DM55_RS09845	COG2801	Transposase and inactivated derivatives
DM55_RS09865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DM55_RS09890	COG2988	succinylglutamate desuccinylase activity
DM55_RS09900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DM55_RS09910	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DM55_RS09935	COG1959	2 iron, 2 sulfur cluster binding
DM55_RS09945	COG2151	metal-sulfur cluster biosynthetic enzyme
DM55_RS09950	COG0822	iron-sulfur transferase activity
DM55_RS09955	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DM55_RS09965	COG0396	ATPase activity
DM55_RS09980	COG0840	transmembrane signaling receptor activity
DM55_RS09985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DM55_RS09990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DM55_RS10005	COG0826	peptidase U32
DM55_RS10010	COG0826	peptidase U32
DM55_RS10015	COG3154	lipid carrier protein
DM55_RS10050	COG2151	metal-sulfur cluster biosynthetic enzyme
DM55_RS10070	COG0415	Belongs to the DNA photolyase family
DM55_RS10075	COG0529	Catalyzes the synthesis of activated sulfate
DM55_RS10110	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DM55_RS10125	COG0402	S-adenosylhomocysteine deaminase activity
DM55_RS10150	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DM55_RS10155	COG0174	glutamine synthetase
DM55_RS10165	COG2963	transposase activity
DM55_RS10170	COG2801	Transposase and inactivated derivatives
DM55_RS10185	COG0583	DNA-binding transcription factor activity
DM55_RS10200	COG0175	sulfate reduction
DM55_RS10210	COG2895	sulfate adenylyltransferase (ATP) activity
DM55_RS10215	COG1648	precorrin-2 dehydrogenase activity
DM55_RS10215	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DM55_RS10230	COG0795	lipopolysaccharide-transporting ATPase activity
DM55_RS10250	COG4654	Cytochrome c, class I
DM55_RS10265	COG0583	DNA-binding transcription factor activity
DM55_RS10295	COG4206	TonB-dependent receptor
DM55_RS10305	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DM55_RS10310	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DM55_RS10315	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DM55_RS10330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DM55_RS10350	COG1492	cobalamin metabolic process
DM55_RS10355	COG2259	Doxx family
DM55_RS10360	COG0489	protein tyrosine kinase activity
DM55_RS10375	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DM55_RS10385	COG0729	surface antigen
DM55_RS10390	COG2911	Protein conserved in bacteria
DM55_RS10410	COG3047	cAMP biosynthetic process
DM55_RS10410	COG2885	chlorophyll binding
DM55_RS10415	COG0489	protein tyrosine kinase activity
DM55_RS10440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DM55_RS10465	COG2801	Transposase and inactivated derivatives
DM55_RS10470	COG2963	transposase activity
DM55_RS10480	COG1914	H( )-stimulated, divalent metal cation uptake system
DM55_RS10505	COG2814	Major facilitator Superfamily
DM55_RS10510	COG0583	DNA-binding transcription factor activity
DM55_RS10550	COG2197	response regulator
DM55_RS10555	COG1538	Outer membrane efflux protein
DM55_RS10565	COG2814	Major facilitator Superfamily
DM55_RS10570	COG1566	PFAM secretion protein HlyD family protein
DM55_RS10580	COG3511	phospholipase C
DM55_RS10585	COG1858	cytochrome C peroxidase
DM55_RS10605	COG1051	belongs to the nudix hydrolase family
DM55_RS10610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DM55_RS10620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DM55_RS10645	COG2963	transposase activity
DM55_RS10650	COG2801	Transposase and inactivated derivatives
DM55_RS10655	COG0477	Major facilitator Superfamily
DM55_RS10660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DM55_RS10670	COG2816	NAD+ diphosphatase activity
DM55_RS10685	COG0824	Thioesterase
DM55_RS10695	COG0411	ABC transporter
DM55_RS10705	COG3718	enzyme involved in inositol metabolism
DM55_RS10715	COG3962	Belongs to the TPP enzyme family
DM55_RS10730	COG1172	Belongs to the binding-protein-dependent transport system permease family
DM55_RS10745	COG0673	inositol 2-dehydrogenase activity
DM55_RS10750	COG0673	inositol 2-dehydrogenase activity
DM55_RS10755	COG0425	Belongs to the sulfur carrier protein TusA family
DM55_RS10765	COG0745	RESPONSE REGULATOR receiver
DM55_RS10775	COG5002	protein histidine kinase activity
DM55_RS10785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DM55_RS10790	COG0525	valine-tRNA ligase activity
DM55_RS10795	COG0210	DNA helicase
DM55_RS10800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DM55_RS10805	COG2223	nitrite transmembrane transporter activity
DM55_RS10810	COG0840	transmembrane signaling receptor activity
DM55_RS10840	COG0583	DNA-binding transcription factor activity
DM55_RS10855	COG0277	FAD linked oxidase domain protein
DM55_RS10870	COG1295	ribonuclease BN
DM55_RS10885	COG0477	Major facilitator Superfamily
DM55_RS10910	COG2801	Transposase and inactivated derivatives
DM55_RS10915	COG2801	Transposase and inactivated derivatives
DM55_RS10920	COG2963	transposase activity
DM55_RS10935	COG2226	methyltransferase
DM55_RS10970	COG2271	Major facilitator Superfamily
DM55_RS10985	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DM55_RS10990	COG2827	Endonuclease containing a URI domain
DM55_RS11010	COG0347	Belongs to the P(II) protein family
DM55_RS11030	COG4215	(ABC) transporter
DM55_RS11070	COG1176	ABC-type spermidine putrescine transport system, permease component I
DM55_RS11075	COG1116	anion transmembrane transporter activity
DM55_RS11080	COG2801	Transposase and inactivated derivatives
DM55_RS11085	COG2963	transposase activity
DM55_RS11105	COG0583	DNA-binding transcription factor activity
DM55_RS11110	COG1960	acyl-CoA dehydrogenase activity
DM55_RS11120	COG0477	Major facilitator Superfamily
DM55_RS11130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DM55_RS11130	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DM55_RS11135	COG1643	Atp-dependent helicase
DM55_RS11155	COG1058	Belongs to the CinA family
DM55_RS11155	COG1546	Belongs to the CinA family
DM55_RS11165	COG0174	glutamine synthetase
DM55_RS11190	COG2197	response regulator
DM55_RS11195	COG4585	Histidine kinase
DM55_RS11200	COG2181	nitrate reductase activity
DM55_RS11205	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DM55_RS11210	COG1140	nitrate reductase beta subunit
DM55_RS11215	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DM55_RS11220	COG2223	nitrite transmembrane transporter activity
DM55_RS11235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DM55_RS11240	COG0339	signal peptide processing
DM55_RS11250	COG4566	intracellular signal transduction
DM55_RS11260	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DM55_RS11265	COG0508	dehydrogenase complex catalyzes the overall conversion of
DM55_RS11270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DM55_RS11300	COG2963	transposase activity
DM55_RS11305	COG2801	Transposase and inactivated derivatives
DM55_RS11340	COG1773	rubredoxin
DM55_RS11350	COG0488	(ABC) transporter
DM55_RS11375	COG0583	DNA-binding transcription factor activity
DM55_RS11385	COG0583	DNA-binding transcription factor activity
DM55_RS11390	COG0477	Major facilitator Superfamily
DM55_RS11425	COG2801	Transposase and inactivated derivatives
DM55_RS11435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DM55_RS11460	COG0859	PFAM glycosyl transferase family 9
DM55_RS11515	COG1129	ABC transporter
DM55_RS11525	COG0559	Belongs to the binding-protein-dependent transport system permease family
DM55_RS11535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DM55_RS11545	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DM55_RS11555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DM55_RS11575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DM55_RS11590	COG2226	methyltransferase
DM55_RS11610	COG0762	integral membrane protein
DM55_RS11635	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DM55_RS11645	COG0436	Aminotransferase
DM55_RS11670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DM55_RS11670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DM55_RS11690	COG2814	Major facilitator Superfamily
DM55_RS11705	COG1126	abc transporter atp-binding protein
DM55_RS11710	COG0765	amino acid transport
DM55_RS11715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DM55_RS11725	COG0363	glucosamine-6-phosphate deaminase activity
DM55_RS11730	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DM55_RS11740	COG1175	transmembrane transport
DM55_RS11745	COG0395	ABC-type sugar transport system, permease component
DM55_RS11750	COG3842	ATPase activity
DM55_RS11755	COG2860	membrane
DM55_RS11760	COG1193	negative regulation of DNA recombination
DM55_RS11765	COG0492	ferredoxin-NADP+ reductase activity
DM55_RS11770	COG1674	ftsk spoiiie
DM55_RS11775	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DM55_RS11785	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DM55_RS11820	COG2894	cell division
DM55_RS11845	COG0859	PFAM glycosyl transferase family 9
DM55_RS11855	COG0477	Major facilitator Superfamily
DM55_RS11885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DM55_RS11890	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DM55_RS11900	COG1561	YicC-like family, N-terminal region
DM55_RS11915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DM55_RS11945	COG2801	Transposase and inactivated derivatives
DM55_RS11950	COG2963	transposase activity
DM55_RS11965	COG2885	chlorophyll binding
DM55_RS11970	COG0823	Involved in the tonB-independent uptake of proteins
DM55_RS11990	COG0824	Thioesterase
DM55_RS11995	COG4221	oxidoreductase activity
DM55_RS12050	COG0450	alkyl hydroperoxide reductase
DM55_RS12060	COG1960	acyl-CoA dehydrogenase activity
DM55_RS12085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DM55_RS12095	COG2814	Major facilitator Superfamily
DM55_RS12115	COG2814	Major facilitator Superfamily
DM55_RS12120	COG0778	Nitroreductase
DM55_RS12125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DM55_RS12130	COG0583	DNA-binding transcription factor activity
DM55_RS12135	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DM55_RS12160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DM55_RS12175	COG4774	siderophore transport
DM55_RS12180	COG1120	ATPase activity
DM55_RS12195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DM55_RS12230	COG0730	response to heat
DM55_RS12240	COG0584	glycerophosphoryl diester phosphodiesterase
DM55_RS12250	COG1280	lysine exporter protein (LysE YggA)
DM55_RS12300	COG0604	alcohol dehydrogenase
DM55_RS12305	COG1733	regulation of RNA biosynthetic process
DM55_RS12315	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DM55_RS12330	COG1773	rubredoxin
DM55_RS12350	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DM55_RS12425	COG1215	transferase activity, transferring glycosyl groups
DM55_RS12440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DM55_RS12450	COG2801	Transposase and inactivated derivatives
DM55_RS12485	COG0456	acetyltransferase
DM55_RS12490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DM55_RS12495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DM55_RS12495	COG0543	2 iron, 2 sulfur cluster binding
DM55_RS12510	COG1187	pseudouridine synthase activity
DM55_RS12520	COG0583	DNA-binding transcription factor activity
DM55_RS12530	COG2267	carboxylic ester hydrolase activity
DM55_RS12535	COG2258	MOSC domain
DM55_RS12540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DM55_RS12550	COG1396	sequence-specific DNA binding
DM55_RS12560	COG2801	Transposase and inactivated derivatives
DM55_RS12565	COG2963	transposase activity
DM55_RS12570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DM55_RS12575	COG0697	spore germination
DM55_RS12585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DM55_RS12605	COG4106	trans-aconitate 2-methyltransferase activity
DM55_RS12620	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DM55_RS12630	COG3135	benzoate transporter
DM55_RS12670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DM55_RS12675	COG2878	Part of a membrane complex involved in electron transport
DM55_RS12680	COG1309	transcriptional regulator
DM55_RS12690	COG3387	PFAM Glycoside hydrolase 15-related
DM55_RS12695	COG2706	6-phosphogluconolactonase activity
DM55_RS12705	COG1674	ftsk spoiiie
DM55_RS12735	COG0513	Belongs to the DEAD box helicase family
DM55_RS12740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DM55_RS12780	COG0438	transferase activity, transferring glycosyl groups
DM55_RS12785	COG0859	PFAM glycosyl transferase family 9
DM55_RS12815	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DM55_RS12820	COG1595	DNA-templated transcription, initiation
DM55_RS12855	COG2233	PERMEase
DM55_RS12875	COG0799	negative regulation of ribosome biogenesis
DM55_RS12890	COG0151	Belongs to the GarS family
DM55_RS12905	COG1028	Short-chain dehydrogenase reductase Sdr
DM55_RS12925	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DM55_RS12930	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DM55_RS12945	COG2205	protein histidine kinase activity
DM55_RS12950	COG0745	RESPONSE REGULATOR receiver
DM55_RS12980	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DM55_RS12990	COG0154	amidase activity
DM55_RS13005	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DM55_RS13010	COG1028	Short-chain dehydrogenase reductase Sdr
DM55_RS13030	COG0438	transferase activity, transferring glycosyl groups
DM55_RS13060	COG0028	Belongs to the TPP enzyme family
DM55_RS13080	COG1183	phosphatidylcholine synthase activity
DM55_RS13085	COG2963	transposase activity
DM55_RS13090	COG2801	Transposase and inactivated derivatives
DM55_RS13100	COG0659	secondary active sulfate transmembrane transporter activity
DM55_RS13105	COG0288	reversible hydration of carbon dioxide
DM55_RS13115	COG0683	leucine binding
DM55_RS13130	COG0604	alcohol dehydrogenase
DM55_RS13130	COG3321	synthase
DM55_RS13130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DM55_RS13130	COG4221	oxidoreductase activity
DM55_RS13135	COG0149	triose-phosphate isomerase activity
DM55_RS13170	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DM55_RS13180	COG1034	ATP synthesis coupled electron transport
DM55_RS13215	COG1007	ATP synthesis coupled electron transport
DM55_RS13235	COG1960	acyl-CoA dehydrogenase activity
DM55_RS13240	COG1960	acyl-CoA dehydrogenase activity
DM55_RS13245	COG1012	belongs to the aldehyde dehydrogenase family
DM55_RS13245	COG2030	dehydratase
DM55_RS13265	COG1960	acyl-CoA dehydrogenase activity
DM55_RS13275	COG0588	phosphoglycerate mutase activity
DM55_RS13280	COG1024	Enoyl-CoA hydratase
DM55_RS13290	COG0436	Aminotransferase
DM55_RS13305	COG2866	Carboxypeptidase
DM55_RS13360	COG1959	2 iron, 2 sulfur cluster binding
DM55_RS13375	COG1522	sequence-specific DNA binding
DM55_RS13380	COG3842	ATPase activity
DM55_RS13385	COG1176	ABC-type spermidine putrescine transport system, permease component I
DM55_RS13390	COG1840	ABC-type Fe3 transport system, periplasmic component
DM55_RS13405	COG1289	transmembrane transporter activity
DM55_RS13420	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DM55_RS13425	COG1074	ATP-dependent DNA helicase activity
DM55_RS13430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DM55_RS13440	COG2200	EAL domain
DM55_RS13460	COG2963	transposase activity
DM55_RS13465	COG2801	Transposase and inactivated derivatives
DM55_RS13485	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
DM55_RS13490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DM55_RS13500	COG0697	spore germination
DM55_RS13505	COG2814	Major facilitator Superfamily
DM55_RS13525	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DM55_RS13530	COG3842	ATPase activity
DM55_RS13535	COG1177	transmembrane transport
DM55_RS13550	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DM55_RS13555	COG1840	ABC-type Fe3 transport system, periplasmic component
DM55_RS13560	COG1609	Transcriptional regulator
DM55_RS13590	COG2963	transposase activity
DM55_RS13620	COG1522	sequence-specific DNA binding
DM55_RS13640	COG0583	DNA-binding transcription factor activity
DM55_RS13670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DM55_RS13705	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DM55_RS13710	COG1250	3-hydroxyacyl-CoA dehydrogenase
DM55_RS13715	COG0583	DNA-binding transcription factor activity
DM55_RS13740	COG3052	prosthetic group binding
DM55_RS13760	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DM55_RS13770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DM55_RS13795	COG2963	transposase activity
DM55_RS13810	COG0477	Major facilitator Superfamily
DM55_RS13820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DM55_RS13825	COG0328	RNA-DNA hybrid ribonuclease activity
DM55_RS13830	COG2226	methyltransferase
DM55_RS13835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DM55_RS13840	COG1388	LysM domain
DM55_RS13840	COG0741	lytic transglycosylase activity
DM55_RS13860	COG0505	Belongs to the CarA family
DM55_RS13870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DM55_RS13875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DM55_RS13885	COG1534	Rna-binding protein
DM55_RS13895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DM55_RS13900	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DM55_RS13910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DM55_RS13915	COG0573	inorganic phosphate transmembrane transporter activity
DM55_RS13920	COG0581	inorganic phosphate transmembrane transporter activity
DM55_RS13935	COG0745	RESPONSE REGULATOR receiver
DM55_RS13945	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DM55_RS14010	COG0534	Mate efflux family protein
DM55_RS14020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DM55_RS14025	COG4942	peptidase
DM55_RS14035	COG2801	Transposase and inactivated derivatives
DM55_RS14060	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DM55_RS14105	COG0366	Alpha amylase catalytic
DM55_RS14110	COG0366	Alpha amylase catalytic
DM55_RS14150	COG0583	DNA-binding transcription factor activity
DM55_RS14155	COG0745	RESPONSE REGULATOR receiver
DM55_RS14200	COG0859	PFAM glycosyl transferase family 9
DM55_RS14200	COG0457	Tetratricopeptide repeat
DM55_RS14270	COG2801	Transposase and inactivated derivatives
DM55_RS14290	COG1538	Outer membrane efflux protein
DM55_RS14295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM55_RS14310	COG0038	chloride channel
DM55_RS14315	COG2855	membrane
DM55_RS14335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DM55_RS14350	COG1609	Transcriptional regulator
DM55_RS14440	COG0598	Magnesium transport protein CorA
DM55_RS14465	COG1196	nuclear chromosome segregation
DM55_RS14465	COG3264	Mechanosensitive ion channel
DM55_RS14495	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DM55_RS14510	COG4263	nitrous-oxide reductase activity
DM55_RS14530	COG0840	transmembrane signaling receptor activity
DM55_RS14540	COG2376	Dihydroxyacetone kinase
DM55_RS14555	COG0475	glutathione-regulated potassium exporter activity
DM55_RS14620	COG3121	Chaperone
DM55_RS14655	COG5295	Hep Hag repeat protein
DM55_RS14670	COG2197	response regulator
DM55_RS14680	COG2963	transposase activity
DM55_RS14685	COG0765	amino acid transport
DM55_RS14690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DM55_RS14745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DM55_RS14750	COG1116	anion transmembrane transporter activity
DM55_RS14780	COG2801	Transposase and inactivated derivatives
DM55_RS14785	COG2766	serine protein kinase
DM55_RS14790	COG2718	Belongs to the UPF0229 family
DM55_RS14795	COG2719	SpoVR family
DM55_RS14800	COG0477	Major facilitator Superfamily
DM55_RS14815	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DM55_RS14820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DM55_RS14840	COG4964	Belongs to the GSP D family
DM55_RS14885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DM55_RS14900	COG4597	amino acid ABC transporter
DM55_RS14905	COG0765	amino acid transport
DM55_RS14910	COG0739	heme binding
DM55_RS14915	COG1309	transcriptional regulator
DM55_RS14925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM55_RS14930	COG3121	Chaperone
DM55_RS14940	COG2375	cellular response to nickel ion
DM55_RS14940	COG1132	(ABC) transporter
DM55_RS14950	COG2963	transposase activity
DM55_RS14975	COG1879	ABC-type sugar transport system periplasmic component
DM55_RS14985	COG1172	Belongs to the binding-protein-dependent transport system permease family
DM55_RS14990	COG1063	alcohol dehydrogenase
DM55_RS14995	COG1070	Carbohydrate kinase
DM55_RS15000	COG1028	Short-chain dehydrogenase reductase Sdr
DM55_RS15025	COG1120	ATPase activity
DM55_RS15065	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DM55_RS15070	COG4774	siderophore transport
DM55_RS15075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DM55_RS15100	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DM55_RS15130	COG0400	carboxylic ester hydrolase activity
DM55_RS15140	COG3979	chitinase
DM55_RS15160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DM55_RS15170	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DM55_RS15190	COG1649	PFAM Uncharacterised BCR, COG1649
DM55_RS15195	COG2807	transmembrane transport
DM55_RS15200	COG1846	Transcriptional regulator
DM55_RS15215	COG0625	glutathione transferase activity
DM55_RS15225	COG0583	DNA-binding transcription factor activity
DM55_RS15245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DM55_RS15250	COG2235	arginine
DM55_RS15265	COG1174	glycine betaine transport
DM55_RS15270	COG1125	glycine betaine transport
DM55_RS15275	COG1174	glycine betaine transport
DM55_RS15280	COG1732	Glycine betaine
DM55_RS15290	COG0477	Major facilitator Superfamily
DM55_RS15295	COG0318	PFAM AMP-dependent synthetase and ligase
DM55_RS15315	COG0835	chemotaxis
DM55_RS15325	COG2207	Transcriptional regulator
DM55_RS15330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DM55_RS15350	COG3251	PFAM MbtH domain protein
DM55_RS15365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DM55_RS15370	COG2801	Transposase and inactivated derivatives
DM55_RS15375	COG2801	Transposase and inactivated derivatives
DM55_RS15385	COG1028	Short-chain dehydrogenase reductase Sdr
DM55_RS15420	COG1028	Short-chain dehydrogenase reductase Sdr
DM55_RS15435	COG0583	DNA-binding transcription factor activity
DM55_RS15445	COG2267	carboxylic ester hydrolase activity
DM55_RS15450	COG0251	oxidation-reduction process
DM55_RS15455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DM55_RS15470	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DM55_RS15490	COG0072	phenylalanine-tRNA ligase activity
DM55_RS15490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DM55_RS15495	COG0776	regulation of translation
DM55_RS15525	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DM55_RS15585	COG0583	DNA-binding transcription factor activity
DM55_RS15590	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DM55_RS15595	COG1187	pseudouridine synthase activity
DM55_RS15605	COG2251	uridine kinase activity
DM55_RS15605	COG0195	Participates in both transcription termination and antitermination
DM55_RS15620	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DM55_RS15625	COG2814	Major facilitator Superfamily
DM55_RS15630	COG1566	PFAM secretion protein HlyD family protein
DM55_RS15640	COG1846	Transcriptional regulator
DM55_RS15645	COG1217	gtp-binding protein TYPA
DM55_RS15650	COG0567	Dehydrogenase, E1 component
DM55_RS15655	COG0508	dehydrogenase complex catalyzes the overall conversion of
DM55_RS15660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DM55_RS15665	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DM55_RS15695	COG2801	Transposase and inactivated derivatives
DM55_RS15700	COG2963	transposase activity
DM55_RS15705	COG2192	nodulation
DM55_RS15720	COG0673	inositol 2-dehydrogenase activity
DM55_RS15725	COG1802	Transcriptional regulator
DM55_RS15730	COG2801	Transposase and inactivated derivatives
DM55_RS15735	COG2963	transposase activity
DM55_RS15745	COG3023	N-Acetylmuramoyl-L-alanine amidase
DM55_RS15755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DM55_RS15760	COG0557	exoribonuclease II activity
DM55_RS15780	COG0840	transmembrane signaling receptor activity
DM55_RS15805	COG0519	Catalyzes the synthesis of GMP from XMP
DM55_RS15815	COG2814	Major facilitator Superfamily
DM55_RS15825	COG0318	PFAM AMP-dependent synthetase and ligase
DM55_RS15890	COG4964	Belongs to the GSP D family
DM55_RS15915	COG2801	Transposase and inactivated derivatives
DM55_RS15920	COG2963	transposase activity
DM55_RS15930	COG1177	transmembrane transport
DM55_RS15935	COG1176	ABC-type spermidine putrescine transport system, permease component I
DM55_RS15940	COG3842	ATPase activity
DM55_RS15945	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DM55_RS15950	COG1914	H( )-stimulated, divalent metal cation uptake system
DM55_RS15960	COG3047	cAMP biosynthetic process
DM55_RS15965	COG2070	2-Nitropropane dioxygenase
DM55_RS15980	COG0488	(ABC) transporter
DM55_RS15985	COG2982	Protein involved in outer membrane biogenesis
DM55_RS15990	COG1122	ATPase activity
DM55_RS15995	COG0390	transport system, permease component
DM55_RS16005	COG0560	Phosphoserine phosphatase
DM55_RS16010	COG0626	cystathionine gamma-synthase activity
DM55_RS16020	COG0183	Belongs to the thiolase family
DM55_RS16040	COG1028	Short-chain dehydrogenase reductase Sdr
DM55_RS16045	COG0183	Belongs to the thiolase family
DM55_RS16050	COG3243	poly(R)-hydroxyalkanoic acid synthase
DM55_RS16060	COG0564	pseudouridine synthase activity
DM55_RS16070	COG1199	ATP-dependent helicase activity
DM55_RS16085	COG2183	response to ionizing radiation
DM55_RS16095	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DM55_RS16115	COG0330	HflC and HflK could
DM55_RS16120	COG0330	HflC and HflK could
DM55_RS16125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DM55_RS16140	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DM55_RS16175	COG0670	Belongs to the BI1 family
DM55_RS16245	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DM55_RS16300	COG0534	Mate efflux family protein
DM55_RS16520	COG1024	Enoyl-CoA hydratase
DM55_RS16520	COG1250	3-hydroxyacyl-CoA dehydrogenase
DM55_RS16550	COG0047	phosphoribosylformylglycinamidine synthase activity
DM55_RS16550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DM55_RS16715	COG4208	sulfate ABC transporter
DM55_RS16720	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DM55_RS16865	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DM55_RS17190	COG2171	N-acyltransferase activity
DM55_RS17420	COG0024	Methionine aminopeptidase
DM55_RS17730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DM55_RS17980	COG0196	riboflavin kinase activity
DM55_RS18215	COG0515	serine threonine protein kinase
DM55_RS18555	COG1960	acyl-CoA dehydrogenase activity
DM55_RS18700	COG0747	negative chemotaxis
DM55_RS18805	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DM55_RS18865	COG2233	PERMEase
DM55_RS19185	COG0418	dihydroorotase activity
DM55_RS19580	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DM55_RS19680	COG0678	peroxiredoxin activity
DM55_RS19920	COG0583	DNA-binding transcription factor activity
DM55_RS20165	COG0443	Heat shock 70 kDa protein
DM55_RS20225	COG0308	aminopeptidase N
DM55_RS20500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DM55_RS20675	COG3186	Phenylalanine-4-hydroxylase
DM55_RS21300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DM55_RS21345	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DM55_RS21380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DM55_RS21415	COG1194	a g-specific adenine glycosylase
DM55_RS21820	COG0183	Belongs to the thiolase family
DM55_RS22080	COG2801	Transposase and inactivated derivatives
DM55_RS22170	COG0514	ATP-dependent DNA helicase (RecQ)
DM55_RS22275	COG4232	protein-disulfide reductase activity
DM55_RS22455	COG2151	metal-sulfur cluster biosynthetic enzyme
DM55_RS22655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DM55_RS22860	COG0312	modulator of DNA gyrase
DM55_RS23120	COG0604	alcohol dehydrogenase
DM55_RS23120	COG3321	synthase
DM55_RS23170	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DM55_RS23255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DM55_RS23385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DM55_RS23385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DM55_RS23490	COG0477	Major facilitator Superfamily
DM55_RS23725	COG1702	phosphate starvation-inducible protein PhoH
DM55_RS24010	COG0126	phosphoglycerate kinase activity
DM55_RS24550	COG0308	aminopeptidase N
DM55_RS24670	COG3383	formate dehydrogenase (NAD+) activity
DM55_RS25050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DM55_RS25090	COG1530	ribonuclease E activity