locus-tag	class	description
DM78_RS00090	COG1250	3-hydroxyacyl-CoA dehydrogenase
DM78_RS00090	COG1024	Enoyl-CoA hydratase
DM78_RS00215	COG1012	belongs to the aldehyde dehydrogenase family
DM78_RS00445	COG0318	PFAM AMP-dependent synthetase and ligase
DM78_RS00580	COG0531	amino acid
DM78_RS00810	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DM78_RS00990	COG0308	aminopeptidase N
DM78_RS01300	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
DM78_RS01455	COG0009	L-threonylcarbamoyladenylate synthase
DM78_RS01770	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DM78_RS01800	COG1702	phosphate starvation-inducible protein PhoH
DM78_RS01995	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DM78_RS02145	COG0772	Belongs to the SEDS family
DM78_RS03130	COG1172	Belongs to the binding-protein-dependent transport system permease family
DM78_RS03230	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DM78_RS03420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DM78_RS03430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DM78_RS03510	COG0243	molybdopterin cofactor binding
DM78_RS03730	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DM78_RS05005	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DM78_RS05290	COG0719	Fe-S assembly protein
DM78_RS06265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM78_RS06355	COG1070	Carbohydrate kinase
DM78_RS06455	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DM78_RS06455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DM78_RS06605	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DM78_RS06705	COG1174	glycine betaine transport
DM78_RS06750	COG0697	spore germination
DM78_RS06865	COG1609	Transcriptional regulator
DM78_RS06950	COG3264	Mechanosensitive ion channel
DM78_RS06950	COG1511	domain protein
DM78_RS07135	COG3188	usher protein
DM78_RS07140	COG3188	usher protein
DM78_RS07155	COG5295	Hep Hag repeat protein
DM78_RS07215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DM78_RS07480	COG2801	Transposase and inactivated derivatives
DM78_RS07515	COG1914	H( )-stimulated, divalent metal cation uptake system
DM78_RS07635	COG0564	pseudouridine synthase activity
DM78_RS07665	COG2183	response to ionizing radiation
DM78_RS07890	COG0542	response to heat
DM78_RS08110	COG2130	NADP-dependent
DM78_RS08190	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DM78_RS08190	COG0047	phosphoribosylformylglycinamidine synthase activity
DM78_RS08195	COG0047	phosphoribosylformylglycinamidine synthase activity
DM78_RS08195	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DM78_RS08355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DM78_RS08965	COG2895	sulfate adenylyltransferase (ATP) activity
DM78_RS08965	COG0529	Catalyzes the synthesis of activated sulfate
DM78_RS09050	COG1695	Transcriptional regulator
DM78_RS09075	COG1960	acyl-CoA dehydrogenase activity
DM78_RS09080	COG0183	Belongs to the thiolase family
DM78_RS09085	COG1250	3-hydroxyacyl-CoA dehydrogenase
DM78_RS09085	COG1024	Enoyl-CoA hydratase
DM78_RS09090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DM78_RS09110	COG2963	transposase activity
DM78_RS09115	COG2801	Transposase and inactivated derivatives
DM78_RS09120	COG0582	viral genome integration into host DNA
DM78_RS09130	COG3245	cytochrome
DM78_RS09135	COG0210	DNA helicase
DM78_RS09150	COG0673	inositol 2-dehydrogenase activity
DM78_RS09165	COG0509	glycine decarboxylation via glycine cleavage system
DM78_RS09180	COG1760	l-serine dehydratase
DM78_RS09205	COG1012	belongs to the aldehyde dehydrogenase family
DM78_RS09220	COG4303	Ethanolamine ammonia lyase large subunit
DM78_RS09255	COG0519	Catalyzes the synthesis of GMP from XMP
DM78_RS09255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DM78_RS09260	COG1902	pentaerythritol trinitrate reductase activity
DM78_RS09275	COG0642	Histidine kinase
DM78_RS09285	COG2801	Transposase and inactivated derivatives
DM78_RS09290	COG2963	transposase activity
DM78_RS09305	COG3186	Phenylalanine-4-hydroxylase
DM78_RS09310	COG1522	sequence-specific DNA binding
DM78_RS09320	COG0583	DNA-binding transcription factor activity
DM78_RS09330	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DM78_RS09350	COG0559	Belongs to the binding-protein-dependent transport system permease family
DM78_RS09395	COG1192	Involved in chromosome partitioning
DM78_RS09400	COG1475	DNA binding
DM78_RS09405	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DM78_RS09415	COG0356	it plays a direct role in the translocation of protons across the membrane
DM78_RS09455	COG0318	PFAM AMP-dependent synthetase and ligase
DM78_RS09460	COG1832	CoA-binding protein
DM78_RS09475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DM78_RS09485	COG0506	proline dehydrogenase activity
DM78_RS09485	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DM78_RS09485	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DM78_RS09500	COG1960	acyl-CoA dehydrogenase activity
DM78_RS09510	COG0436	Aminotransferase
DM78_RS09530	COG0277	FAD linked oxidase domain protein
DM78_RS09540	COG0789	Transcriptional regulator
DM78_RS09560	COG0668	transmembrane transport
DM78_RS09580	COG0531	amino acid
DM78_RS09625	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DM78_RS09635	COG1175	transmembrane transport
DM78_RS09640	COG0395	ABC-type sugar transport system, permease component
DM78_RS09645	COG3842	ATPase activity
DM78_RS09650	COG0584	glycerophosphoryl diester phosphodiesterase
DM78_RS09665	COG0067	glutamate synthase
DM78_RS09665	COG0070	glutamate synthase
DM78_RS09665	COG0069	glutamate synthase activity
DM78_RS09685	COG4178	(ABC) transporter
DM78_RS09710	COG1127	ABC transporter
DM78_RS09715	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DM78_RS09720	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DM78_RS09740	COG1131	(ABC) transporter
DM78_RS09745	COG0842	Transport permease protein
DM78_RS09755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DM78_RS09765	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DM78_RS09770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DM78_RS09780	COG2095	MarC family integral membrane protein
DM78_RS09825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DM78_RS09830	COG0805	protein transport
DM78_RS09840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DM78_RS09845	COG2963	transposase activity
DM78_RS09850	COG2801	Transposase and inactivated derivatives
DM78_RS09860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DM78_RS09865	COG0723	plastoquinol--plastocyanin reductase activity
DM78_RS09870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DM78_RS09875	COG2857	Cytochrome c1
DM78_RS09880	COG0625	glutathione transferase activity
DM78_RS09885	COG2969	positive regulation of protein catabolic process
DM78_RS09900	COG4695	Portal protein
DM78_RS09905	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DM78_RS09910	COG3657	addiction module killer protein
DM78_RS09915	COG2963	transposase activity
DM78_RS09920	COG2801	Transposase and inactivated derivatives
DM78_RS10005	COG0308	aminopeptidase N
DM78_RS10050	COG0443	Heat shock 70 kDa protein
DM78_RS10060	COG1278	Cold shock
DM78_RS10065	COG2963	transposase activity
DM78_RS10070	COG2801	Transposase and inactivated derivatives
DM78_RS10075	COG1113	amino acid transport
DM78_RS10090	COG2823	Periplasmic or secreted lipoprotein
DM78_RS10095	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DM78_RS10125	COG0728	peptidoglycan biosynthetic process
DM78_RS10140	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DM78_RS10145	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DM78_RS10155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DM78_RS10160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DM78_RS10165	COG0318	PFAM AMP-dependent synthetase and ligase
DM78_RS10170	COG4974	Belongs to the 'phage' integrase family
DM78_RS10180	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DM78_RS10185	COG0802	atpase or kinase
DM78_RS10190	COG0860	N-Acetylmuramoyl-L-alanine amidase
DM78_RS10200	COG1741	Belongs to the pirin family
DM78_RS10205	COG3118	belongs to the thioredoxin family
DM78_RS10215	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DM78_RS10225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DM78_RS10240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DM78_RS10250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DM78_RS10255	COG1522	sequence-specific DNA binding
DM78_RS10275	COG2271	Major facilitator Superfamily
DM78_RS10285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DM78_RS10290	COG1012	belongs to the aldehyde dehydrogenase family
DM78_RS10300	COG0583	DNA-binding transcription factor activity
DM78_RS10305	COG0246	Mannitol dehydrogenase
DM78_RS10310	COG1070	Carbohydrate kinase
DM78_RS10315	COG2390	Transcriptional regulator
DM78_RS10330	COG0583	DNA-binding transcription factor activity
DM78_RS10340	COG3842	ATPase activity
DM78_RS10345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DM78_RS10355	COG1175	transmembrane transport
DM78_RS10370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DM78_RS10380	COG0735	belongs to the Fur family
DM78_RS10390	COG1121	(ABC) transporter
DM78_RS10395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DM78_RS10400	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DM78_RS10415	COG1070	Carbohydrate kinase
DM78_RS10420	COG2233	PERMEase
DM78_RS10425	COG2963	transposase activity
DM78_RS10430	COG2801	Transposase and inactivated derivatives
DM78_RS10445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM78_RS10450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM78_RS10475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DM78_RS10505	COG0009	L-threonylcarbamoyladenylate synthase
DM78_RS10510	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DM78_RS10515	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DM78_RS10520	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DM78_RS10530	COG0469	pyruvate kinase activity
DM78_RS10535	COG0126	phosphoglycerate kinase activity
DM78_RS10560	COG0859	PFAM glycosyl transferase family 9
DM78_RS10570	COG0429	hydrolase of the alpha beta-hydrolase fold
DM78_RS10580	COG4783	chaperone-mediated protein folding
DM78_RS10590	COG2963	transposase activity
DM78_RS10595	COG2801	Transposase and inactivated derivatives
DM78_RS10610	COG3307	-O-antigen
DM78_RS10615	COG4969	Belongs to the N-Me-Phe pilin family
DM78_RS10620	COG0861	Integral membrane protein TerC family
DM78_RS10625	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DM78_RS10640	COG2137	regulation of response to DNA damage stimulus
DM78_RS10645	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DM78_RS10675	COG2801	Transposase and inactivated derivatives
DM78_RS10680	COG2963	transposase activity
DM78_RS10725	COG4948	Mandelate Racemase Muconate Lactonizing
DM78_RS10745	COG0513	Belongs to the DEAD box helicase family
DM78_RS10785	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DM78_RS10790	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DM78_RS10800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DM78_RS10805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DM78_RS10810	COG0367	asparagine synthase
DM78_RS10825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DM78_RS10835	COG1396	sequence-specific DNA binding
DM78_RS10840	COG2814	Major facilitator Superfamily
DM78_RS10845	COG0583	DNA-binding transcription factor activity
DM78_RS10855	COG1702	phosphate starvation-inducible protein PhoH
DM78_RS10865	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DM78_RS10875	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DM78_RS10880	COG0752	glycyl-tRNA synthetase alpha subunit
DM78_RS10885	COG0751	glycine-tRNA ligase activity
DM78_RS10890	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DM78_RS10895	COG0204	Acyl-transferase
DM78_RS10920	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DM78_RS10925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DM78_RS10940	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DM78_RS10950	COG5265	(ABC) transporter
DM78_RS10965	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DM78_RS10970	COG1024	Enoyl-CoA hydratase
DM78_RS10975	COG0183	Belongs to the thiolase family
DM78_RS10980	COG1024	Enoyl-CoA hydratase
DM78_RS10980	COG1250	3-hydroxyacyl-CoA dehydrogenase
DM78_RS10985	COG1960	acyl-CoA dehydrogenase activity
DM78_RS11000	COG0494	nUDIX hydrolase
DM78_RS11065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DM78_RS11075	COG0251	oxidation-reduction process
DM78_RS11080	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DM78_RS11105	COG0477	Major facilitator Superfamily
DM78_RS11130	COG0708	Exodeoxyribonuclease III
DM78_RS11135	COG2326	polyphosphate kinase activity
DM78_RS11155	COG1077	Cell shape determining protein MreB Mrl
DM78_RS11170	COG0768	penicillin binding
DM78_RS11175	COG0772	Belongs to the SEDS family
DM78_RS11195	COG0720	synthase
DM78_RS11200	COG0602	queuosine metabolic process
DM78_RS11215	COG2204	response regulator
DM78_RS11220	COG5000	phosphorelay sensor kinase activity
DM78_RS11230	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DM78_RS11230	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DM78_RS11245	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DM78_RS11250	COG0242	peptide deformylase activity
DM78_RS11255	COG0758	DNA mediated transformation
DM78_RS11270	COG0583	DNA-binding transcription factor activity
DM78_RS11275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DM78_RS11300	COG2801	Transposase and inactivated derivatives
DM78_RS11305	COG2963	transposase activity
DM78_RS11320	COG4695	Portal protein
DM78_RS11330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DM78_RS11345	COG0583	DNA-binding transcription factor activity
DM78_RS11365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DM78_RS11380	COG2169	Transcriptional regulator
DM78_RS11380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DM78_RS11400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DM78_RS11405	COG2801	Transposase and inactivated derivatives
DM78_RS11410	COG2963	transposase activity
DM78_RS11450	COG0592	DNA-directed DNA polymerase activity
DM78_RS11460	COG2963	transposase activity
DM78_RS11465	COG2801	Transposase and inactivated derivatives
DM78_RS11470	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DM78_RS11525	COG0235	Class ii aldolase
DM78_RS11530	COG5002	protein histidine kinase activity
DM78_RS11530	COG5001	Diguanylate cyclase
DM78_RS11565	COG2204	response regulator
DM78_RS11585	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DM78_RS11595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DM78_RS11610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DM78_RS11615	COG1596	polysaccharide export
DM78_RS11655	COG4977	sequence-specific DNA binding
DM78_RS11655	COG1917	Cupin 2, conserved barrel domain protein
DM78_RS11660	COG0625	glutathione transferase activity
DM78_RS11665	COG0625	glutathione transferase activity
DM78_RS11675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DM78_RS11685	COG0588	phosphoglycerate mutase activity
DM78_RS11725	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DM78_RS11730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DM78_RS11735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DM78_RS11740	COG0006	proline dipeptidase activity
DM78_RS11745	COG0625	glutathione transferase activity
DM78_RS11750	COG0069	glutamate synthase activity
DM78_RS11815	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DM78_RS11815	COG3008	intermembrane lipid transfer
DM78_RS11820	COG2995	paraquat-inducible protein a
DM78_RS11835	COG2353	YceI-like domain
DM78_RS11840	COG2353	YceI-like domain
DM78_RS11850	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DM78_RS11855	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DM78_RS11860	COG1862	Preprotein translocase
DM78_RS11870	COG0343	queuine tRNA-ribosyltransferase activity
DM78_RS11880	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DM78_RS11900	COG0783	Belongs to the Dps family
DM78_RS11925	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DM78_RS11930	COG2188	Transcriptional regulator
DM78_RS11935	COG3624	Phosphonate C-P lyase system protein PhnG
DM78_RS11945	COG3626	phosphonate metabolism
DM78_RS11950	COG3627	carbon phosphorus lyase activity
DM78_RS11955	COG4107	phosphonate C-P lyase system protein PhnK
DM78_RS11960	COG4778	phosphonate C-P lyase system protein PhnL
DM78_RS11965	COG3454	Phosphonate metabolism
DM78_RS11970	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DM78_RS11975	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DM78_RS11980	COG3639	organic phosphonate transmembrane transporter activity
DM78_RS11995	COG0247	lactate metabolic process
DM78_RS12000	COG0277	FAD linked oxidase domain protein
DM78_RS12005	COG0277	FAD linked oxidase domain protein
DM78_RS12010	COG0277	FAD linked oxidase domain protein
DM78_RS12015	COG2096	Adenosyltransferase
DM78_RS12020	COG1017	nitric oxide dioxygenase activity
DM78_RS12020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DM78_RS12040	COG0418	dihydroorotase activity
DM78_RS12045	COG0121	glutamine amidotransferase
DM78_RS12075	COG1126	abc transporter atp-binding protein
DM78_RS12080	COG0765	amino acid transport
DM78_RS12085	COG0765	amino acid transport
DM78_RS12090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DM78_RS12095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DM78_RS12100	COG0583	DNA-binding transcription factor activity
DM78_RS12105	COG2223	nitrite transmembrane transporter activity
DM78_RS12125	COG0800	Aldolase
DM78_RS12135	COG1737	Transcriptional regulator
DM78_RS12140	COG1981	membrane
DM78_RS12145	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DM78_RS12150	COG1466	dna polymerase III delta subunit
DM78_RS12180	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DM78_RS12185	COG0735	belongs to the Fur family
DM78_RS12195	COG4266	Belongs to the allantoicase family
DM78_RS12200	COG1301	dicarboxylic acid transport
DM78_RS12210	COG0583	DNA-binding transcription factor activity
DM78_RS12225	COG2814	Major facilitator Superfamily
DM78_RS12230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DM78_RS12235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DM78_RS12240	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DM78_RS12250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DM78_RS12280	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DM78_RS12285	COG1546	Belongs to the CinA family
DM78_RS12290	COG0284	orotidine-5'-phosphate decarboxylase activity
DM78_RS12300	COG1028	Short-chain dehydrogenase reductase Sdr
DM78_RS12305	COG1172	Belongs to the binding-protein-dependent transport system permease family
DM78_RS12320	COG1028	Short-chain dehydrogenase reductase Sdr
DM78_RS12330	COG3734	2-keto-3-deoxy-galactonokinase
DM78_RS12335	COG1414	Transcriptional regulator
DM78_RS12350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DM78_RS12355	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DM78_RS12360	COG0557	exoribonuclease II activity
DM78_RS12365	COG3150	esterase
DM78_RS12370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DM78_RS12380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DM78_RS12385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DM78_RS12390	COG0511	ligase activity, forming carbon-carbon bonds
DM78_RS12395	COG0439	Biotin carboxylase
DM78_RS12410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DM78_RS12415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DM78_RS12455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DM78_RS12460	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DM78_RS12465	COG2095	MarC family integral membrane protein
DM78_RS12510	COG0142	geranyltranstransferase activity
DM78_RS12525	COG2801	Transposase and inactivated derivatives
DM78_RS12530	COG2963	transposase activity
DM78_RS12535	COG4536	flavin adenine dinucleotide binding
DM78_RS12540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DM78_RS12550	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DM78_RS12565	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DM78_RS12570	COG0494	nUDIX hydrolase
DM78_RS12580	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DM78_RS12600	COG0678	peroxiredoxin activity
DM78_RS12615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DM78_RS12650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DM78_RS12655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DM78_RS12665	COG3116	cell division
DM78_RS12685	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DM78_RS12695	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DM78_RS12700	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DM78_RS12710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DM78_RS12720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DM78_RS12725	COG0243	molybdopterin cofactor binding
DM78_RS12735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DM78_RS12745	COG0625	glutathione transferase activity
DM78_RS12755	COG0742	ribosomal rna small subunit methyltransferase
DM78_RS12765	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DM78_RS12770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DM78_RS12785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DM78_RS12800	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DM78_RS12815	COG1194	a g-specific adenine glycosylase
DM78_RS12840	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DM78_RS12845	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DM78_RS12850	COG1137	ATPase activity
DM78_RS12865	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DM78_RS12885	COG1280	lysine exporter protein (LysE YggA)
DM78_RS12910	COG2814	Major facilitator Superfamily
DM78_RS12915	COG0629	single-stranded DNA binding
DM78_RS12920	COG2963	transposase activity
DM78_RS12925	COG2801	Transposase and inactivated derivatives
DM78_RS12935	COG3397	chitin binding
DM78_RS12955	COG2267	carboxylic ester hydrolase activity
DM78_RS12985	COG1280	lysine exporter protein (LysE YggA)
DM78_RS13010	COG1028	Short-chain dehydrogenase reductase Sdr
DM78_RS13025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DM78_RS13060	COG0519	Catalyzes the synthesis of GMP from XMP
DM78_RS13070	COG0561	phosphatase activity
DM78_RS13075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DM78_RS13085	COG0438	transferase activity, transferring glycosyl groups
DM78_RS13105	COG1360	Flagellar Motor Protein
DM78_RS13110	COG2201	protein-glutamate methylesterase activity
DM78_RS13130	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DM78_RS13145	COG0745	RESPONSE REGULATOR receiver
DM78_RS13150	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DM78_RS13170	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DM78_RS13175	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DM78_RS13200	COG1950	PFAM Membrane protein of
DM78_RS13205	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DM78_RS13225	COG2963	transposase activity
DM78_RS13255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DM78_RS13260	COG1522	sequence-specific DNA binding
DM78_RS13270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DM78_RS13300	COG2963	transposase activity
DM78_RS13305	COG2801	Transposase and inactivated derivatives
DM78_RS13325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DM78_RS13330	COG1570	exodeoxyribonuclease VII activity
DM78_RS13335	COG1663	tetraacyldisaccharide 4'-kinase activity
DM78_RS13360	COG1278	Cold shock
DM78_RS13370	COG0542	response to heat
DM78_RS13375	COG1113	amino acid transport
DM78_RS13380	COG2801	Transposase and inactivated derivatives
DM78_RS13385	COG2963	transposase activity
DM78_RS13395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DM78_RS13420	COG0859	PFAM glycosyl transferase family 9
DM78_RS13475	COG1129	ABC transporter
DM78_RS13485	COG0559	Belongs to the binding-protein-dependent transport system permease family
DM78_RS13495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DM78_RS13505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DM78_RS13515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DM78_RS13545	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DM78_RS13550	COG2226	methyltransferase
DM78_RS13570	COG0762	integral membrane protein
DM78_RS13595	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DM78_RS13605	COG0436	Aminotransferase
DM78_RS13630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DM78_RS13630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DM78_RS13650	COG2814	Major facilitator Superfamily
DM78_RS13665	COG1126	abc transporter atp-binding protein
DM78_RS13670	COG0765	amino acid transport
DM78_RS13675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DM78_RS13685	COG0363	glucosamine-6-phosphate deaminase activity
DM78_RS13690	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DM78_RS13700	COG1175	transmembrane transport
DM78_RS13705	COG0395	ABC-type sugar transport system, permease component
DM78_RS13710	COG3842	ATPase activity
DM78_RS13715	COG2860	membrane
DM78_RS13720	COG1193	negative regulation of DNA recombination
DM78_RS13725	COG0492	ferredoxin-NADP+ reductase activity
DM78_RS13730	COG1674	ftsk spoiiie
DM78_RS13735	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DM78_RS13745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DM78_RS13780	COG2894	cell division
DM78_RS13805	COG0859	PFAM glycosyl transferase family 9
DM78_RS13815	COG0477	Major facilitator Superfamily
DM78_RS13845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DM78_RS13850	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DM78_RS13860	COG1561	YicC-like family, N-terminal region
DM78_RS13875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DM78_RS13900	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DM78_RS13910	COG2801	Transposase and inactivated derivatives
DM78_RS13920	COG2801	Transposase and inactivated derivatives
DM78_RS13925	COG1278	Cold shock
DM78_RS13930	COG2176	DNA-directed DNA polymerase activity
DM78_RS13950	COG4772	TonB-dependent receptor
DM78_RS13995	COG0583	DNA-binding transcription factor activity
DM78_RS14005	COG0308	aminopeptidase N
DM78_RS14015	COG2119	membrane
DM78_RS14020	COG0402	S-adenosylhomocysteine deaminase activity
DM78_RS14030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DM78_RS14045	COG0154	amidase activity
DM78_RS14050	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DM78_RS14075	COG3383	formate dehydrogenase (NAD+) activity
DM78_RS14090	COG1910	domain protein
DM78_RS14100	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DM78_RS14110	COG2801	Transposase and inactivated derivatives
DM78_RS14115	COG2963	transposase activity
DM78_RS14125	COG0546	phosphoglycolate phosphatase activity
DM78_RS14150	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DM78_RS14155	COG1605	Chorismate mutase
DM78_RS14155	COG0077	Prephenate dehydratase
DM78_RS14160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DM78_RS14185	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DM78_RS14195	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DM78_RS14220	COG2951	lytic endotransglycosylase activity
DM78_RS14225	COG0123	including yeast histone deacetylase and acetoin utilization protein
DM78_RS14230	COG2267	carboxylic ester hydrolase activity
DM78_RS14240	COG2011	ABC-type metal ion transport system permease component
DM78_RS14320	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DM78_RS14335	COG0501	Belongs to the peptidase M48B family
DM78_RS14345	COG0521	Mo-molybdopterin cofactor biosynthetic process
DM78_RS14350	COG3028	Belongs to the UPF0307 family
DM78_RS14355	COG0312	modulator of DNA gyrase
DM78_RS14365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DM78_RS14370	COG2204	response regulator
DM78_RS14400	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DM78_RS14415	COG0640	Transcriptional regulator
DM78_RS14430	COG0114	fumarate hydratase activity
DM78_RS14440	COG2963	transposase activity
DM78_RS14445	COG2801	Transposase and inactivated derivatives
DM78_RS14450	COG0534	Mate efflux family protein
DM78_RS14455	COG2501	S4 domain
DM78_RS14475	COG3045	CreA protein
DM78_RS14490	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DM78_RS14495	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DM78_RS14515	COG1322	Protein conserved in bacteria
DM78_RS14530	COG0303	'Molybdopterin
DM78_RS14540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DM78_RS14545	COG1530	ribonuclease E activity
DM78_RS14580	COG1399	metal-binding, possibly nucleic acid-binding protein
DM78_RS14615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DM78_RS14635	COG3026	antisigma factor binding
DM78_RS14640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DM78_RS14655	COG0681	Belongs to the peptidase S26 family
DM78_RS14660	COG0571	ribonuclease III activity
DM78_RS14665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DM78_RS14670	COG1381	Involved in DNA repair and RecF pathway recombination
DM78_RS14675	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DM78_RS14690	COG2204	response regulator
DM78_RS14710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DM78_RS14735	COG1956	GAF domain-containing protein
DM78_RS14740	COG0583	DNA-binding transcription factor activity
DM78_RS14750	COG2153	protein acetylation
DM78_RS14765	COG1999	signal sequence binding
DM78_RS14775	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DM78_RS14780	COG1132	(ABC) transporter
DM78_RS14785	COG0438	transferase activity, transferring glycosyl groups
DM78_RS14800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DM78_RS14805	COG0683	leucine binding
DM78_RS14810	COG2963	transposase activity
DM78_RS14815	COG2801	Transposase and inactivated derivatives
DM78_RS14820	COG3511	phospholipase C
DM78_RS14830	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DM78_RS14835	COG0596	Alpha beta hydrolase
DM78_RS14840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DM78_RS14855	COG3394	polysaccharide catabolic process
DM78_RS14865	COG2963	transposase activity
DM78_RS14870	COG2801	Transposase and inactivated derivatives
DM78_RS14890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DM78_RS14915	COG2988	succinylglutamate desuccinylase activity
DM78_RS14925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DM78_RS14935	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DM78_RS14960	COG1959	2 iron, 2 sulfur cluster binding
DM78_RS14970	COG2151	metal-sulfur cluster biosynthetic enzyme
DM78_RS14975	COG0822	iron-sulfur transferase activity
DM78_RS14980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DM78_RS14990	COG0396	ATPase activity
DM78_RS15005	COG0840	transmembrane signaling receptor activity
DM78_RS15010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DM78_RS15015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DM78_RS15030	COG0826	peptidase U32
DM78_RS15035	COG0826	peptidase U32
DM78_RS15040	COG3154	lipid carrier protein
DM78_RS15075	COG2151	metal-sulfur cluster biosynthetic enzyme
DM78_RS15095	COG0415	Belongs to the DNA photolyase family
DM78_RS15100	COG0529	Catalyzes the synthesis of activated sulfate
DM78_RS15135	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DM78_RS15150	COG0402	S-adenosylhomocysteine deaminase activity
DM78_RS15175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DM78_RS15180	COG0174	glutamine synthetase
DM78_RS15190	COG2963	transposase activity
DM78_RS15195	COG2801	Transposase and inactivated derivatives
DM78_RS15210	COG0583	DNA-binding transcription factor activity
DM78_RS15225	COG0175	sulfate reduction
DM78_RS15235	COG2895	sulfate adenylyltransferase (ATP) activity
DM78_RS15240	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DM78_RS15240	COG1648	precorrin-2 dehydrogenase activity
DM78_RS15260	COG0795	lipopolysaccharide-transporting ATPase activity
DM78_RS15280	COG4654	Cytochrome c, class I
DM78_RS15295	COG0583	DNA-binding transcription factor activity
DM78_RS15325	COG4206	TonB-dependent receptor
DM78_RS15335	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DM78_RS15340	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DM78_RS15345	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DM78_RS15360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DM78_RS15380	COG1492	cobalamin metabolic process
DM78_RS15385	COG2259	Doxx family
DM78_RS15390	COG0489	protein tyrosine kinase activity
DM78_RS15405	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DM78_RS15415	COG0729	surface antigen
DM78_RS15420	COG2911	Protein conserved in bacteria
DM78_RS15440	COG2885	chlorophyll binding
DM78_RS15440	COG3047	cAMP biosynthetic process
DM78_RS15445	COG0489	protein tyrosine kinase activity
DM78_RS15470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DM78_RS15490	COG2801	Transposase and inactivated derivatives
DM78_RS15495	COG2963	transposase activity
DM78_RS15515	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DM78_RS15525	COG2801	Transposase and inactivated derivatives
DM78_RS15530	COG2963	transposase activity
DM78_RS15555	COG4964	Belongs to the GSP D family
DM78_RS15620	COG0318	PFAM AMP-dependent synthetase and ligase
DM78_RS15630	COG2814	Major facilitator Superfamily
DM78_RS15640	COG0519	Catalyzes the synthesis of GMP from XMP
DM78_RS15665	COG0840	transmembrane signaling receptor activity
DM78_RS15685	COG0557	exoribonuclease II activity
DM78_RS15690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DM78_RS15700	COG3023	N-Acetylmuramoyl-L-alanine amidase
DM78_RS15715	COG0673	inositol 2-dehydrogenase activity
DM78_RS15720	COG2801	Transposase and inactivated derivatives
DM78_RS15725	COG2963	transposase activity
DM78_RS15730	COG0765	amino acid transport
DM78_RS15735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DM78_RS15790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DM78_RS15795	COG1116	anion transmembrane transporter activity
DM78_RS15820	COG2963	transposase activity
DM78_RS15825	COG2801	Transposase and inactivated derivatives
DM78_RS15840	COG1301	dicarboxylic acid transport
DM78_RS15865	COG0667	Aldo Keto reductase
DM78_RS15870	COG0701	Predicted permease
DM78_RS15910	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DM78_RS15915	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DM78_RS15920	COG4208	sulfate ABC transporter
DM78_RS15925	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DM78_RS15930	COG0583	DNA-binding transcription factor activity
DM78_RS15935	COG2963	transposase activity
DM78_RS15940	COG2801	Transposase and inactivated derivatives
DM78_RS15945	COG2766	serine protein kinase
DM78_RS15950	COG2718	Belongs to the UPF0229 family
DM78_RS15955	COG2719	SpoVR family
DM78_RS15960	COG0477	Major facilitator Superfamily
DM78_RS15975	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DM78_RS15980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DM78_RS16000	COG4964	Belongs to the GSP D family
DM78_RS16045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DM78_RS16060	COG4597	amino acid ABC transporter
DM78_RS16065	COG0765	amino acid transport
DM78_RS16070	COG0739	heme binding
DM78_RS16075	COG1309	transcriptional regulator
DM78_RS16085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM78_RS16100	COG3539	Fimbrial protein
DM78_RS16110	COG3121	Chaperone
DM78_RS16120	COG2375	cellular response to nickel ion
DM78_RS16120	COG1132	(ABC) transporter
DM78_RS16130	COG2963	transposase activity
DM78_RS16135	COG2801	Transposase and inactivated derivatives
DM78_RS16155	COG1879	ABC-type sugar transport system periplasmic component
DM78_RS16165	COG1172	Belongs to the binding-protein-dependent transport system permease family
DM78_RS16170	COG1063	alcohol dehydrogenase
DM78_RS16175	COG1070	Carbohydrate kinase
DM78_RS16180	COG1028	Short-chain dehydrogenase reductase Sdr
DM78_RS16210	COG1120	ATPase activity
DM78_RS16250	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DM78_RS16255	COG4774	siderophore transport
DM78_RS16260	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DM78_RS16285	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DM78_RS16315	COG0400	carboxylic ester hydrolase activity
DM78_RS16325	COG3979	chitinase
DM78_RS16345	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DM78_RS16355	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DM78_RS16375	COG1649	PFAM Uncharacterised BCR, COG1649
DM78_RS16380	COG2807	transmembrane transport
DM78_RS16385	COG1846	Transcriptional regulator
DM78_RS16400	COG0625	glutathione transferase activity
DM78_RS16410	COG0583	DNA-binding transcription factor activity
DM78_RS16430	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DM78_RS16435	COG2235	arginine
DM78_RS16450	COG1174	glycine betaine transport
DM78_RS16455	COG1125	glycine betaine transport
DM78_RS16460	COG1174	glycine betaine transport
DM78_RS16465	COG1732	Glycine betaine
DM78_RS16475	COG0477	Major facilitator Superfamily
DM78_RS16480	COG0318	PFAM AMP-dependent synthetase and ligase
DM78_RS16500	COG0835	chemotaxis
DM78_RS16510	COG2207	Transcriptional regulator
DM78_RS16515	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DM78_RS16535	COG3251	PFAM MbtH domain protein
DM78_RS16550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DM78_RS16555	COG2801	Transposase and inactivated derivatives
DM78_RS16560	COG2963	transposase activity
DM78_RS16575	COG1538	Outer membrane efflux protein
DM78_RS16580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM78_RS16595	COG0038	chloride channel
DM78_RS16600	COG2855	membrane
DM78_RS16620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DM78_RS16635	COG1609	Transcriptional regulator
DM78_RS16725	COG0598	Magnesium transport protein CorA
DM78_RS16750	COG3264	Mechanosensitive ion channel
DM78_RS16750	COG1196	nuclear chromosome segregation
DM78_RS16780	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DM78_RS16795	COG4263	nitrous-oxide reductase activity
DM78_RS16815	COG0840	transmembrane signaling receptor activity
DM78_RS16825	COG2376	Dihydroxyacetone kinase
DM78_RS16845	COG0475	glutathione-regulated potassium exporter activity
DM78_RS16910	COG3121	Chaperone
DM78_RS16945	COG5295	Hep Hag repeat protein
DM78_RS16960	COG2197	response regulator
DM78_RS16970	COG2801	Transposase and inactivated derivatives
DM78_RS16980	COG2192	nodulation
DM78_RS17005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DM78_RS17025	COG0165	Argininosuccinate lyase
DM78_RS17030	COG0137	argininosuccinate synthase activity
DM78_RS17045	COG2963	transposase activity
DM78_RS17050	COG2801	Transposase and inactivated derivatives
DM78_RS17080	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DM78_RS17085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DM78_RS17090	COG0508	dehydrogenase complex catalyzes the overall conversion of
DM78_RS17095	COG0567	Dehydrogenase, E1 component
DM78_RS17100	COG1217	gtp-binding protein TYPA
DM78_RS17105	COG1846	Transcriptional regulator
DM78_RS17115	COG1566	PFAM secretion protein HlyD family protein
DM78_RS17120	COG2814	Major facilitator Superfamily
DM78_RS17125	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DM78_RS17140	COG0195	Participates in both transcription termination and antitermination
DM78_RS17140	COG2251	uridine kinase activity
DM78_RS17150	COG1187	pseudouridine synthase activity
DM78_RS17155	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DM78_RS17160	COG0583	DNA-binding transcription factor activity
DM78_RS17210	COG2963	transposase activity
DM78_RS17220	COG1177	transmembrane transport
DM78_RS17225	COG1176	ABC-type spermidine putrescine transport system, permease component I
DM78_RS17230	COG3842	ATPase activity
DM78_RS17235	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DM78_RS17250	COG3047	cAMP biosynthetic process
DM78_RS17255	COG2070	2-Nitropropane dioxygenase
DM78_RS17270	COG0488	(ABC) transporter
DM78_RS17275	COG2982	Protein involved in outer membrane biogenesis
DM78_RS17280	COG1122	ATPase activity
DM78_RS17285	COG0390	transport system, permease component
DM78_RS17295	COG0560	Phosphoserine phosphatase
DM78_RS17300	COG0626	cystathionine gamma-synthase activity
DM78_RS17310	COG0183	Belongs to the thiolase family
DM78_RS17330	COG1028	Short-chain dehydrogenase reductase Sdr
DM78_RS17335	COG0183	Belongs to the thiolase family
DM78_RS17340	COG3243	poly(R)-hydroxyalkanoic acid synthase
DM78_RS17350	COG0564	pseudouridine synthase activity
DM78_RS17360	COG1199	ATP-dependent helicase activity
DM78_RS17375	COG2183	response to ionizing radiation
DM78_RS17385	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DM78_RS17405	COG0330	HflC and HflK could
DM78_RS17410	COG0330	HflC and HflK could
DM78_RS17415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DM78_RS17430	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DM78_RS17465	COG0670	Belongs to the BI1 family
DM78_RS17510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DM78_RS17525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DM78_RS17540	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DM78_RS17545	COG0789	Transcriptional regulator
DM78_RS17550	COG0477	Major facilitator Superfamily
DM78_RS17555	COG3228	Belongs to the MtfA family
DM78_RS17570	COG0534	Mate efflux family protein
DM78_RS17600	COG0542	response to heat
DM78_RS17605	COG1959	2 iron, 2 sulfur cluster binding
DM78_RS17610	COG2346	COG2346, Truncated hemoglobins
DM78_RS17615	COG0314	molybdopterin synthase activity
DM78_RS17620	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DM78_RS17640	COG0436	Aminotransferase
DM78_RS17650	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DM78_RS17655	COG2076	Multidrug Resistance protein
DM78_RS17660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DM78_RS17665	COG0463	Glycosyl transferase, family 2
DM78_RS17675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DM78_RS17675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DM78_RS17680	COG0726	polysaccharide deacetylase
DM78_RS17685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DM78_RS17690	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DM78_RS17695	COG0791	NLP P60 protein
DM78_RS17700	COG0306	phosphate transporter
DM78_RS17740	COG1595	DNA-templated transcription, initiation
DM78_RS17755	COG2801	Transposase and inactivated derivatives
DM78_RS17760	COG0252	asparaginase activity
DM78_RS17785	COG0438	transferase activity, transferring glycosyl groups
DM78_RS17810	COG0084	hydrolase, TatD family'
DM78_RS17815	COG1247	-acetyltransferase
DM78_RS17830	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DM78_RS17835	COG0354	folic acid binding
DM78_RS17850	COG0657	acetylesterase activity
DM78_RS17855	COG2130	NADP-dependent
DM78_RS17875	COG0183	Belongs to the thiolase family
DM78_RS17880	COG1335	isochorismatase
DM78_RS17885	COG1250	3-hydroxyacyl-CoA dehydrogenase
DM78_RS17885	COG1024	Enoyl-CoA hydratase
DM78_RS17890	COG0318	PFAM AMP-dependent synthetase and ligase
DM78_RS17915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DM78_RS17925	COG0047	phosphoribosylformylglycinamidine synthase activity
DM78_RS17925	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DM78_RS17935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DM78_RS17950	COG4181	ATPase activity
DM78_RS18005	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DM78_RS18025	COG1929	Belongs to the glycerate kinase type-1 family
DM78_RS18030	COG1846	Transcriptional regulator
DM78_RS18035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DM78_RS18070	COG2963	transposase activity
DM78_RS18075	COG2801	Transposase and inactivated derivatives
DM78_RS18120	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DM78_RS18135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DM78_RS18180	COG2801	Transposase and inactivated derivatives
DM78_RS18185	COG2963	transposase activity
DM78_RS18205	COG4266	Belongs to the allantoicase family
DM78_RS18210	COG3195	allantoin biosynthetic process
DM78_RS18210	COG3648	Uricase
DM78_RS18225	COG1953	Uracil, thiamine, allantoin
DM78_RS18240	COG1619	proteins homologs of microcin C7 resistance protein MccF
DM78_RS18295	COG0697	spore germination
DM78_RS18305	COG2867	negative regulation of translational initiation
DM78_RS18315	COG0330	HflC and HflK could
DM78_RS18350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DM78_RS18390	COG0750	zinc metalloprotease
DM78_RS18405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DM78_RS18435	COG0024	Methionine aminopeptidase
DM78_RS18445	COG1187	pseudouridine synthase activity
DM78_RS18450	COG0242	peptide deformylase activity
DM78_RS18490	COG1393	Belongs to the ArsC family
DM78_RS18500	COG2890	protein-(glutamine-N5) methyltransferase activity
DM78_RS18515	COG0386	Belongs to the glutathione peroxidase family
DM78_RS18520	COG0488	(ABC) transporter
DM78_RS18540	COG0477	Major facilitator Superfamily
DM78_RS18545	COG0351	phosphomethylpyrimidine kinase
DM78_RS18570	COG1214	PFAM Peptidase M22, glycoprotease
DM78_RS18580	COG0513	Belongs to the DEAD box helicase family
DM78_RS18590	COG2224	Isocitrate lyase
DM78_RS18600	COG0583	DNA-binding transcription factor activity
DM78_RS18610	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DM78_RS18660	COG1752	Esterase of the alpha-beta hydrolase superfamily
DM78_RS18665	COG0791	NLP P60 protein
DM78_RS18670	COG4172	Belongs to the ABC transporter superfamily
DM78_RS18675	COG4239	(ABC) transporter, permease
DM78_RS18680	COG4174	ABC transporter (Permease)
DM78_RS18685	COG4166	transmembrane transport
DM78_RS18705	COG0243	molybdopterin cofactor binding
DM78_RS18715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DM78_RS18730	COG0024	Methionine aminopeptidase
DM78_RS18745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DM78_RS18765	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DM78_RS18780	COG3958	Transketolase
DM78_RS18785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DM78_RS18805	COG2175	clavaminate synthase activity
DM78_RS18835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DM78_RS18840	COG2895	sulfate adenylyltransferase (ATP) activity
DM78_RS18840	COG0529	Catalyzes the synthesis of activated sulfate
DM78_RS18845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM78_RS18850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM78_RS18880	COG0527	aspartate kinase activity
DM78_RS18885	COG0037	tRNA processing
DM78_RS18910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DM78_RS18920	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DM78_RS18925	COG1045	serine acetyltransferase
DM78_RS18935	COG0483	inositol monophosphate 1-phosphatase activity
DM78_RS18965	COG2850	peptidyl-arginine hydroxylation
DM78_RS18970	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DM78_RS18975	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DM78_RS18980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DM78_RS18990	COG0180	Tryptophanyl-tRNA synthetase
DM78_RS18995	COG1994	Peptidase M50
DM78_RS19000	COG0009	L-threonylcarbamoyladenylate synthase
DM78_RS19005	COG0613	PHP domain protein
DM78_RS19010	COG0596	Alpha beta hydrolase
DM78_RS19015	COG2833	Protein of unknown function (DUF455)
DM78_RS19025	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DM78_RS19035	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DM78_RS19055	COG2267	carboxylic ester hydrolase activity
DM78_RS19065	COG0084	hydrolase, TatD family'
DM78_RS19070	COG1136	(ABC) transporter
DM78_RS19085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DM78_RS19105	COG2975	iron-sulfur cluster assembly
DM78_RS19125	COG0316	Belongs to the HesB IscA family
DM78_RS19130	COG0822	iron-sulfur transferase activity
DM78_RS19135	COG1104	cysteine desulfurase activity
DM78_RS19145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DM78_RS19165	COG1414	Transcriptional regulator
DM78_RS19190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DM78_RS19195	COG0508	dehydrogenase complex catalyzes the overall conversion of
DM78_RS19200	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DM78_RS19210	COG4566	intracellular signal transduction
DM78_RS19220	COG0339	signal peptide processing
DM78_RS19225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DM78_RS19240	COG2223	nitrite transmembrane transporter activity
DM78_RS19245	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DM78_RS19250	COG1140	nitrate reductase beta subunit
DM78_RS19255	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DM78_RS19260	COG2181	nitrate reductase activity
DM78_RS19265	COG4585	Histidine kinase
DM78_RS19270	COG2197	response regulator
DM78_RS19300	COG0174	glutamine synthetase
DM78_RS19310	COG1546	Belongs to the CinA family
DM78_RS19310	COG1058	Belongs to the CinA family
DM78_RS19330	COG1643	Atp-dependent helicase
DM78_RS19335	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DM78_RS19335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DM78_RS19345	COG0477	Major facilitator Superfamily
DM78_RS19355	COG1960	acyl-CoA dehydrogenase activity
DM78_RS19360	COG0583	DNA-binding transcription factor activity
DM78_RS19375	COG2963	transposase activity
DM78_RS19380	COG2801	Transposase and inactivated derivatives
DM78_RS19385	COG1116	anion transmembrane transporter activity
DM78_RS19390	COG1176	ABC-type spermidine putrescine transport system, permease component I
DM78_RS19430	COG4215	(ABC) transporter
DM78_RS19450	COG0347	Belongs to the P(II) protein family
DM78_RS19470	COG2827	Endonuclease containing a URI domain
DM78_RS19475	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DM78_RS19490	COG2271	Major facilitator Superfamily
DM78_RS19525	COG2963	transposase activity
DM78_RS19530	COG2801	Transposase and inactivated derivatives
DM78_RS19545	COG0776	regulation of translation
DM78_RS19550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DM78_RS19550	COG0072	phenylalanine-tRNA ligase activity
DM78_RS19570	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DM78_RS19585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DM78_RS19590	COG0251	oxidation-reduction process
DM78_RS19595	COG2267	carboxylic ester hydrolase activity
DM78_RS19605	COG0583	DNA-binding transcription factor activity
DM78_RS19620	COG1028	Short-chain dehydrogenase reductase Sdr
DM78_RS19655	COG1028	Short-chain dehydrogenase reductase Sdr
DM78_RS19665	COG2801	Transposase and inactivated derivatives
DM78_RS19670	COG2963	transposase activity
DM78_RS19675	COG2801	Transposase and inactivated derivatives
DM78_RS19680	COG2801	Transposase and inactivated derivatives
DM78_RS19705	COG0477	Major facilitator Superfamily
DM78_RS19720	COG1295	ribonuclease BN
DM78_RS19735	COG0277	FAD linked oxidase domain protein
DM78_RS19750	COG0583	DNA-binding transcription factor activity
DM78_RS19780	COG0840	transmembrane signaling receptor activity
DM78_RS19785	COG2223	nitrite transmembrane transporter activity
DM78_RS19790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DM78_RS19795	COG0210	DNA helicase
DM78_RS19800	COG0525	valine-tRNA ligase activity
DM78_RS19805	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DM78_RS19825	COG0745	RESPONSE REGULATOR receiver
DM78_RS19835	COG0425	Belongs to the sulfur carrier protein TusA family
DM78_RS19840	COG0673	inositol 2-dehydrogenase activity
DM78_RS19845	COG0673	inositol 2-dehydrogenase activity
DM78_RS19860	COG1172	Belongs to the binding-protein-dependent transport system permease family
DM78_RS19875	COG3962	Belongs to the TPP enzyme family
DM78_RS19885	COG3718	enzyme involved in inositol metabolism
DM78_RS19895	COG0411	ABC transporter
DM78_RS19905	COG0824	Thioesterase
DM78_RS19920	COG2816	NAD+ diphosphatase activity
DM78_RS19930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DM78_RS19935	COG0477	Major facilitator Superfamily
DM78_RS19940	COG2801	Transposase and inactivated derivatives
DM78_RS19945	COG2963	transposase activity
DM78_RS19965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DM78_RS19975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DM78_RS19980	COG1051	belongs to the nudix hydrolase family
DM78_RS20000	COG1858	cytochrome C peroxidase
DM78_RS20005	COG3511	phospholipase C
DM78_RS20015	COG1566	PFAM secretion protein HlyD family protein
DM78_RS20020	COG2814	Major facilitator Superfamily
DM78_RS20030	COG1538	Outer membrane efflux protein
DM78_RS20035	COG2197	response regulator
DM78_RS20075	COG0583	DNA-binding transcription factor activity
DM78_RS20080	COG2814	Major facilitator Superfamily
DM78_RS20105	COG1914	H( )-stimulated, divalent metal cation uptake system
DM78_RS20115	COG2801	Transposase and inactivated derivatives
DM78_RS20120	COG2963	transposase activity
DM78_RS20130	COG4942	peptidase
DM78_RS20135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DM78_RS20145	COG0534	Mate efflux family protein
DM78_RS20185	COG2963	transposase activity
DM78_RS20190	COG2801	Transposase and inactivated derivatives
DM78_RS20220	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DM78_RS20230	COG0745	RESPONSE REGULATOR receiver
DM78_RS20245	COG0581	inorganic phosphate transmembrane transporter activity
DM78_RS20250	COG0573	inorganic phosphate transmembrane transporter activity
DM78_RS20255	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DM78_RS20265	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DM78_RS20270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DM78_RS20280	COG1534	Rna-binding protein
DM78_RS20290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DM78_RS20295	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DM78_RS20305	COG0505	Belongs to the CarA family
DM78_RS20325	COG0741	lytic transglycosylase activity
DM78_RS20325	COG1388	LysM domain
DM78_RS20330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DM78_RS20335	COG2226	methyltransferase
DM78_RS20340	COG0328	RNA-DNA hybrid ribonuclease activity
DM78_RS20345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DM78_RS20355	COG0477	Major facilitator Superfamily
DM78_RS20370	COG2963	transposase activity
DM78_RS20375	COG2801	Transposase and inactivated derivatives
DM78_RS20395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DM78_RS20405	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DM78_RS20450	COG0583	DNA-binding transcription factor activity
DM78_RS20455	COG1250	3-hydroxyacyl-CoA dehydrogenase
DM78_RS20460	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DM78_RS20495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DM78_RS20525	COG0583	DNA-binding transcription factor activity
DM78_RS20545	COG1522	sequence-specific DNA binding
DM78_RS20590	COG1609	Transcriptional regulator
DM78_RS20595	COG1840	ABC-type Fe3 transport system, periplasmic component
DM78_RS20600	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DM78_RS20615	COG1177	transmembrane transport
DM78_RS20620	COG3842	ATPase activity
DM78_RS20625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DM78_RS20645	COG2814	Major facilitator Superfamily
DM78_RS20650	COG0697	spore germination
DM78_RS20660	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DM78_RS20665	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
DM78_RS20685	COG2801	Transposase and inactivated derivatives
DM78_RS20690	COG2963	transposase activity
DM78_RS20710	COG2200	EAL domain
DM78_RS20720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DM78_RS20725	COG1074	ATP-dependent DNA helicase activity
DM78_RS20730	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DM78_RS20745	COG1289	transmembrane transporter activity
DM78_RS20760	COG1840	ABC-type Fe3 transport system, periplasmic component
DM78_RS20765	COG1176	ABC-type spermidine putrescine transport system, permease component I
DM78_RS20770	COG3842	ATPase activity
DM78_RS20775	COG1522	sequence-specific DNA binding
DM78_RS20790	COG1959	2 iron, 2 sulfur cluster binding
DM78_RS20840	COG2801	Transposase and inactivated derivatives
DM78_RS20845	COG2963	transposase activity
DM78_RS20855	COG2866	Carboxypeptidase
DM78_RS20870	COG0436	Aminotransferase
DM78_RS20880	COG1024	Enoyl-CoA hydratase
DM78_RS20885	COG0588	phosphoglycerate mutase activity
DM78_RS20895	COG1960	acyl-CoA dehydrogenase activity
DM78_RS20915	COG1012	belongs to the aldehyde dehydrogenase family
DM78_RS20915	COG2030	dehydratase
DM78_RS20920	COG1960	acyl-CoA dehydrogenase activity
DM78_RS20925	COG1960	acyl-CoA dehydrogenase activity
DM78_RS20945	COG1007	ATP synthesis coupled electron transport
DM78_RS20980	COG1034	ATP synthesis coupled electron transport
DM78_RS20990	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DM78_RS21025	COG0149	triose-phosphate isomerase activity
DM78_RS21030	COG4221	oxidoreductase activity
DM78_RS21030	COG3321	synthase
DM78_RS21030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DM78_RS21030	COG0604	alcohol dehydrogenase
DM78_RS21045	COG0683	leucine binding
DM78_RS21055	COG0288	reversible hydration of carbon dioxide
DM78_RS21060	COG0659	secondary active sulfate transmembrane transporter activity
DM78_RS21070	COG1183	phosphatidylcholine synthase activity
DM78_RS21090	COG0028	Belongs to the TPP enzyme family
DM78_RS21120	COG0438	transferase activity, transferring glycosyl groups
DM78_RS21140	COG1028	Short-chain dehydrogenase reductase Sdr
DM78_RS21145	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DM78_RS21160	COG0154	amidase activity
DM78_RS21170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DM78_RS21200	COG0745	RESPONSE REGULATOR receiver
DM78_RS21205	COG2205	protein histidine kinase activity
DM78_RS21220	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DM78_RS21225	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DM78_RS21245	COG1028	Short-chain dehydrogenase reductase Sdr
DM78_RS21260	COG0151	Belongs to the GarS family
DM78_RS21275	COG0799	negative regulation of ribosome biogenesis
DM78_RS21295	COG2233	PERMEase
DM78_RS21330	COG1595	DNA-templated transcription, initiation
DM78_RS21335	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DM78_RS21365	COG0859	PFAM glycosyl transferase family 9
DM78_RS21370	COG0438	transferase activity, transferring glycosyl groups
DM78_RS21410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DM78_RS21415	COG0513	Belongs to the DEAD box helicase family
DM78_RS21440	COG1674	ftsk spoiiie
DM78_RS21445	COG2706	6-phosphogluconolactonase activity
DM78_RS21450	COG3387	PFAM Glycoside hydrolase 15-related
DM78_RS21460	COG1309	transcriptional regulator
DM78_RS21465	COG2878	Part of a membrane complex involved in electron transport
DM78_RS21470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DM78_RS21510	COG3135	benzoate transporter
DM78_RS21525	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DM78_RS21570	COG0697	spore germination
DM78_RS21575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DM78_RS21580	COG2963	transposase activity
DM78_RS21585	COG2801	Transposase and inactivated derivatives
DM78_RS21620	COG0477	Major facilitator Superfamily
DM78_RS21625	COG0583	DNA-binding transcription factor activity
DM78_RS21635	COG0583	DNA-binding transcription factor activity
DM78_RS21660	COG0488	(ABC) transporter
DM78_RS21670	COG1773	rubredoxin
DM78_RS21705	COG2801	Transposase and inactivated derivatives
DM78_RS21710	COG2963	transposase activity
DM78_RS21740	COG0456	acetyltransferase
DM78_RS21745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DM78_RS21750	COG0543	2 iron, 2 sulfur cluster binding
DM78_RS21750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DM78_RS21765	COG1187	pseudouridine synthase activity
DM78_RS21775	COG0583	DNA-binding transcription factor activity
DM78_RS21785	COG2267	carboxylic ester hydrolase activity
DM78_RS21790	COG2258	MOSC domain
DM78_RS21795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DM78_RS21805	COG2963	transposase activity
DM78_RS21810	COG2801	Transposase and inactivated derivatives
DM78_RS21820	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DM78_RS21825	COG1047	Peptidyl-prolyl cis-trans
DM78_RS21845	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DM78_RS21865	COG3264	Mechanosensitive ion channel
DM78_RS21865	COG1511	domain protein
DM78_RS21870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DM78_RS21870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DM78_RS21875	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DM78_RS21880	COG0196	riboflavin kinase activity
DM78_RS21885	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DM78_RS21915	COG2963	transposase activity
DM78_RS21920	COG2801	Transposase and inactivated derivatives
DM78_RS21930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DM78_RS21945	COG1215	transferase activity, transferring glycosyl groups
DM78_RS22020	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DM78_RS22040	COG1773	rubredoxin
DM78_RS22055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DM78_RS22065	COG1733	regulation of RNA biosynthetic process
DM78_RS22070	COG0604	alcohol dehydrogenase
DM78_RS22120	COG1280	lysine exporter protein (LysE YggA)
DM78_RS22130	COG0584	glycerophosphoryl diester phosphodiesterase
DM78_RS22140	COG0730	response to heat
DM78_RS22175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DM78_RS22190	COG1120	ATPase activity
DM78_RS22195	COG4774	siderophore transport
DM78_RS22210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DM78_RS22235	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DM78_RS22245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DM78_RS22250	COG0778	Nitroreductase
DM78_RS22255	COG2814	Major facilitator Superfamily
DM78_RS22275	COG2814	Major facilitator Superfamily
DM78_RS22285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DM78_RS22310	COG1960	acyl-CoA dehydrogenase activity
DM78_RS22320	COG0450	alkyl hydroperoxide reductase
DM78_RS22375	COG4221	oxidoreductase activity
DM78_RS22380	COG0824	Thioesterase
DM78_RS22400	COG0823	Involved in the tonB-independent uptake of proteins
DM78_RS22405	COG2885	chlorophyll binding
DM78_RS22420	COG2963	transposase activity
DM78_RS22425	COG2801	Transposase and inactivated derivatives
DM78_RS22445	COG0156	8-amino-7-oxononanoate synthase activity
DM78_RS22450	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DM78_RS22455	COG0604	alcohol dehydrogenase
DM78_RS22455	COG3321	synthase
DM78_RS22455	COG1028	Short-chain dehydrogenase reductase Sdr
DM78_RS22460	COG1368	sulfuric ester hydrolase activity
DM78_RS22475	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DM78_RS22575	COG0586	Pfam SNARE associated Golgi protein
DM78_RS22580	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DM78_RS22600	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DM78_RS22610	COG0617	tRNA 3'-terminal CCA addition
DM78_RS22615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DM78_RS22620	COG1428	Deoxynucleoside kinase
DM78_RS22630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DM78_RS22675	COG0497	DNA recombination
DM78_RS22680	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DM78_RS22685	COG3164	Protein of unknown function
DM78_RS22690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DM78_RS22695	COG0312	modulator of DNA gyrase
DM78_RS22700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DM78_RS22710	COG1064	alcohol dehydrogenase
DM78_RS22720	COG2207	Transcriptional regulator
DM78_RS22730	COG2814	Major facilitator Superfamily
DM78_RS22745	COG1309	transcriptional regulator
DM78_RS22770	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DM78_RS22795	COG0523	cobalamin synthesis protein
DM78_RS22805	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DM78_RS22820	COG1560	Kdo2-lipid A biosynthetic process
DM78_RS22845	COG0667	Aldo Keto reductase
DM78_RS22860	COG2814	Major facilitator Superfamily
DM78_RS22870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DM78_RS22945	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DM78_RS22960	COG0531	amino acid
DM78_RS22985	COG1280	lysine exporter protein (LysE YggA)
DM78_RS22990	COG3568	Endonuclease Exonuclease Phosphatase
DM78_RS23010	COG0579	oxidoreductase
DM78_RS23025	COG0747	negative chemotaxis
DM78_RS23030	COG0601	transmembrane transport
DM78_RS23040	COG0444	Belongs to the ABC transporter superfamily
DM78_RS23045	COG4608	Belongs to the ABC transporter superfamily
DM78_RS23075	COG1984	allophanate hydrolase subunit 2
DM78_RS23080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DM78_RS23090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DM78_RS23095	COG0741	lytic transglycosylase activity
DM78_RS23125	COG2747	anti-sigma28 factor FlgM
DM78_RS23140	COG1815	bacterial-type flagellum-dependent cell motility
DM78_RS23145	COG1558	bacterial-type flagellum-dependent cell motility
DM78_RS23150	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DM78_RS23155	COG1749	Flagellar hook protein flgE
DM78_RS23170	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DM78_RS23175	COG1706	bacterial-type flagellum-dependent cell motility
DM78_RS23185	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DM78_RS23195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DM78_RS23200	COG2233	PERMEase
DM78_RS23205	COG0583	DNA-binding transcription factor activity
DM78_RS23225	COG2824	Alkylphosphonate utilization operon protein PhnA
DM78_RS23235	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DM78_RS23260	COG2801	Transposase and inactivated derivatives
DM78_RS23265	COG2963	transposase activity
DM78_RS23315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DM78_RS23320	COG4221	oxidoreductase activity
DM78_RS23325	COG1028	Short-chain dehydrogenase reductase Sdr
DM78_RS23335	COG0747	negative chemotaxis
DM78_RS23340	COG0488	(ABC) transporter
DM78_RS23355	COG0288	reversible hydration of carbon dioxide
DM78_RS23360	COG0183	Belongs to the thiolase family
DM78_RS23370	COG3012	SEC-C Motif Domain Protein
DM78_RS23415	COG1785	Belongs to the alkaline phosphatase family
DM78_RS23430	COG2801	Transposase and inactivated derivatives
DM78_RS23435	COG2963	transposase activity
DM78_RS23450	COG0840	transmembrane signaling receptor activity
DM78_RS23455	COG1609	Transcriptional regulator
DM78_RS23505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DM78_RS23525	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DM78_RS23530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DM78_RS23550	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DM78_RS23555	COG1704	LemA family
DM78_RS23630	COG1024	Enoyl-CoA hydratase
DM78_RS23655	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DM78_RS23665	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DM78_RS23680	COG0737	Belongs to the 5'-nucleotidase family
DM78_RS23685	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DM78_RS23690	COG1127	ABC transporter
DM78_RS23725	COG1686	Belongs to the peptidase S11 family
DM78_RS23735	COG2921	Belongs to the UPF0250 family
DM78_RS23740	COG0583	DNA-binding transcription factor activity
DM78_RS23770	COG0840	transmembrane signaling receptor activity
DM78_RS23780	COG1999	signal sequence binding
DM78_RS23790	COG1612	heme a metabolic process
DM78_RS23820	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DM78_RS23830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DM78_RS23845	COG2226	methyltransferase
DM78_RS23850	COG1040	competence protein
DM78_RS23860	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DM78_RS23880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DM78_RS23890	COG0793	Belongs to the peptidase S41A family
DM78_RS23895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DM78_RS23900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DM78_RS23905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DM78_RS23915	COG0189	ligase activity
DM78_RS23930	COG0004	ammonium transporteR
DM78_RS23940	COG2960	long-chain fatty acid transporting porin activity
DM78_RS23970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DM78_RS23990	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DM78_RS24000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DM78_RS24005	COG1960	acyl-CoA dehydrogenase activity
DM78_RS24010	COG1960	acyl-CoA dehydrogenase activity
DM78_RS24015	COG1250	3-hydroxyacyl-CoA dehydrogenase
DM78_RS24015	COG1024	Enoyl-CoA hydratase
DM78_RS24020	COG0583	DNA-binding transcription factor activity
DM78_RS24065	COG1294	oxidase, subunit
DM78_RS24085	COG2190	(PTS) system
DM78_RS24085	COG1263	PTS System
DM78_RS24085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DM78_RS24090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DM78_RS24090	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DM78_RS24095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DM78_RS24100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DM78_RS24105	COG2188	Transcriptional regulator
DM78_RS24110	COG0583	DNA-binding transcription factor activity
DM78_RS24165	COG1960	acyl-CoA dehydrogenase activity
DM78_RS24175	COG2226	methyltransferase
DM78_RS24210	COG2814	Major facilitator Superfamily
DM78_RS24220	COG0587	DNA-directed DNA polymerase activity
DM78_RS24235	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DM78_RS24255	COG2801	Transposase and inactivated derivatives
DM78_RS24260	COG2963	transposase activity
DM78_RS24295	COG3396	Phenylacetate-CoA oxygenase
DM78_RS24300	COG3460	Phenylacetate-CoA oxygenase
DM78_RS24305	COG3396	Phenylacetate-CoA oxygenase
DM78_RS24310	COG2151	metal-sulfur cluster biosynthetic enzyme
DM78_RS24315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DM78_RS24335	COG1522	sequence-specific DNA binding
DM78_RS24355	COG0280	phosphate acetyltransferase
DM78_RS24355	COG0281	malic enzyme
DM78_RS24360	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DM78_RS24365	COG1881	PFAM PEBP family protein
DM78_RS24375	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DM78_RS24390	COG3047	cAMP biosynthetic process
DM78_RS24400	COG2801	Transposase and inactivated derivatives
DM78_RS24405	COG2963	transposase activity
DM78_RS24410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DM78_RS24415	COG1333	cytochrome c biogenesis protein
DM78_RS24435	COG4232	protein-disulfide reductase activity
DM78_RS24480	COG0201	protein transport
DM78_RS24610	COG0514	ATP-dependent DNA helicase (RecQ)
DM78_RS24655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DM78_RS24685	COG2963	transposase activity
DM78_RS24690	COG2801	Transposase and inactivated derivatives
DM78_RS24695	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DM78_RS24700	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DM78_RS24725	COG0523	cobalamin synthesis protein
DM78_RS24745	COG1459	type II secretion system
DM78_RS24760	COG2165	general secretion pathway protein
DM78_RS24805	COG1846	Transcriptional regulator
DM78_RS24810	COG2814	Major facilitator Superfamily
DM78_RS24815	COG0583	DNA-binding transcription factor activity
DM78_RS24825	COG1346	cytolysis
DM78_RS24845	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DM78_RS24860	COG2963	transposase activity
DM78_RS24865	COG2801	Transposase and inactivated derivatives
DM78_RS24875	COG1987	bacterial-type flagellum assembly
DM78_RS24885	COG0789	Transcriptional regulator
DM78_RS24890	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DM78_RS24890	COG4106	trans-aconitate 2-methyltransferase activity
DM78_RS24900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DM78_RS24910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DM78_RS24925	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DM78_RS24940	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DM78_RS24985	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DM78_RS24985	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DM78_RS24990	COG1573	uracil-dna glycosylase