locus-tag	class	description
BHL98_RS00010	COG0592	DNA-directed DNA polymerase activity
BHL98_RS00020	COG2963	transposase activity
BHL98_RS00025	COG2801	Transposase and inactivated derivatives
BHL98_RS00030	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BHL98_RS00095	COG0235	Class ii aldolase
BHL98_RS00100	COG5001	Diguanylate cyclase
BHL98_RS00100	COG5002	protein histidine kinase activity
BHL98_RS00135	COG2204	response regulator
BHL98_RS00155	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BHL98_RS00165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHL98_RS00180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BHL98_RS00185	COG1596	polysaccharide export
BHL98_RS00240	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BHL98_RS00250	COG1175	transmembrane transport
BHL98_RS00255	COG0395	ABC-type sugar transport system, permease component
BHL98_RS00260	COG3842	ATPase activity
BHL98_RS00265	COG0584	glycerophosphoryl diester phosphodiesterase
BHL98_RS00280	COG0067	glutamate synthase
BHL98_RS00280	COG0069	glutamate synthase activity
BHL98_RS00280	COG0070	glutamate synthase
BHL98_RS00290	COG1115	amino acid carrier protein
BHL98_RS00300	COG4178	(ABC) transporter
BHL98_RS00325	COG1127	ABC transporter
BHL98_RS00330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BHL98_RS00335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BHL98_RS00355	COG1131	(ABC) transporter
BHL98_RS00360	COG0842	Transport permease protein
BHL98_RS00370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BHL98_RS00380	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BHL98_RS00385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BHL98_RS00395	COG2095	MarC family integral membrane protein
BHL98_RS00440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BHL98_RS00445	COG0805	protein transport
BHL98_RS00455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHL98_RS00460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BHL98_RS00465	COG0723	plastoquinol--plastocyanin reductase activity
BHL98_RS00470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BHL98_RS00475	COG2857	Cytochrome c1
BHL98_RS00480	COG0625	glutathione transferase activity
BHL98_RS00485	COG2969	positive regulation of protein catabolic process
BHL98_RS00500	COG4695	Portal protein
BHL98_RS00505	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BHL98_RS00510	COG3657	addiction module killer protein
BHL98_RS00515	COG2963	transposase activity
BHL98_RS00520	COG2801	Transposase and inactivated derivatives
BHL98_RS00530	COG1987	bacterial-type flagellum assembly
BHL98_RS00540	COG0789	Transcriptional regulator
BHL98_RS00545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BHL98_RS00545	COG4106	trans-aconitate 2-methyltransferase activity
BHL98_RS00555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BHL98_RS00565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BHL98_RS00580	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BHL98_RS00595	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BHL98_RS00655	COG1695	Transcriptional regulator
BHL98_RS00680	COG1960	acyl-CoA dehydrogenase activity
BHL98_RS00685	COG0183	Belongs to the thiolase family
BHL98_RS00690	COG1024	Enoyl-CoA hydratase
BHL98_RS00690	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHL98_RS00695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BHL98_RS00720	COG2801	Transposase and inactivated derivatives
BHL98_RS00725	COG2963	transposase activity
BHL98_RS00740	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BHL98_RS00755	COG1346	cytolysis
BHL98_RS00765	COG0583	DNA-binding transcription factor activity
BHL98_RS00770	COG2814	Major facilitator Superfamily
BHL98_RS00775	COG1846	Transcriptional regulator
BHL98_RS00820	COG2165	general secretion pathway protein
BHL98_RS00835	COG1459	type II secretion system
BHL98_RS00855	COG0523	cobalamin synthesis protein
BHL98_RS00865	COG1278	Cold shock
BHL98_RS00870	COG2963	transposase activity
BHL98_RS00875	COG2801	Transposase and inactivated derivatives
BHL98_RS00880	COG1113	amino acid transport
BHL98_RS00895	COG2823	Periplasmic or secreted lipoprotein
BHL98_RS00900	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BHL98_RS00920	COG0443	Heat shock 70 kDa protein
BHL98_RS00965	COG0308	aminopeptidase N
BHL98_RS01050	COG2801	Transposase and inactivated derivatives
BHL98_RS01055	COG2963	transposase activity
BHL98_RS01060	COG4536	flavin adenine dinucleotide binding
BHL98_RS01065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BHL98_RS01075	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BHL98_RS01090	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BHL98_RS01095	COG0494	nUDIX hydrolase
BHL98_RS01105	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BHL98_RS01125	COG0678	peroxiredoxin activity
BHL98_RS01140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BHL98_RS01175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BHL98_RS01180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BHL98_RS01190	COG3116	cell division
BHL98_RS01210	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BHL98_RS01225	COG0189	ligase activity
BHL98_RS01235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHL98_RS01240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BHL98_RS01245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BHL98_RS01250	COG0793	Belongs to the peptidase S41A family
BHL98_RS01260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BHL98_RS01280	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BHL98_RS01290	COG1040	competence protein
BHL98_RS01295	COG2226	methyltransferase
BHL98_RS01310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BHL98_RS01320	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BHL98_RS01350	COG1612	heme a metabolic process
BHL98_RS01360	COG1999	signal sequence binding
BHL98_RS01370	COG0840	transmembrane signaling receptor activity
BHL98_RS01385	COG1064	alcohol dehydrogenase
BHL98_RS01395	COG2207	Transcriptional regulator
BHL98_RS01405	COG2814	Major facilitator Superfamily
BHL98_RS01420	COG1309	transcriptional regulator
BHL98_RS01445	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BHL98_RS01465	COG0523	cobalamin synthesis protein
BHL98_RS01475	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BHL98_RS01490	COG1560	Kdo2-lipid A biosynthetic process
BHL98_RS01515	COG0667	Aldo Keto reductase
BHL98_RS01530	COG2814	Major facilitator Superfamily
BHL98_RS01540	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BHL98_RS01615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BHL98_RS01630	COG0531	amino acid
BHL98_RS01655	COG1280	lysine exporter protein (LysE YggA)
BHL98_RS01660	COG3568	Endonuclease Exonuclease Phosphatase
BHL98_RS01680	COG0579	oxidoreductase
BHL98_RS01695	COG0747	negative chemotaxis
BHL98_RS01700	COG0601	transmembrane transport
BHL98_RS01710	COG0444	Belongs to the ABC transporter superfamily
BHL98_RS01715	COG4608	Belongs to the ABC transporter superfamily
BHL98_RS01750	COG1984	allophanate hydrolase subunit 2
BHL98_RS01755	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BHL98_RS01765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BHL98_RS01770	COG0741	lytic transglycosylase activity
BHL98_RS01800	COG2747	anti-sigma28 factor FlgM
BHL98_RS01815	COG1815	bacterial-type flagellum-dependent cell motility
BHL98_RS01820	COG1558	bacterial-type flagellum-dependent cell motility
BHL98_RS01825	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BHL98_RS01830	COG1749	Flagellar hook protein flgE
BHL98_RS01840	COG2801	Transposase and inactivated derivatives
BHL98_RS01845	COG2963	transposase activity
BHL98_RS01855	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BHL98_RS01860	COG1706	bacterial-type flagellum-dependent cell motility
BHL98_RS01870	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BHL98_RS01880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BHL98_RS01885	COG2233	PERMEase
BHL98_RS01890	COG0583	DNA-binding transcription factor activity
BHL98_RS01910	COG2824	Alkylphosphonate utilization operon protein PhnA
BHL98_RS01920	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BHL98_RS01945	COG2801	Transposase and inactivated derivatives
BHL98_RS01950	COG2963	transposase activity
BHL98_RS02020	COG1704	LemA family
BHL98_RS02025	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BHL98_RS02045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHL98_RS02050	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHL98_RS02065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BHL98_RS02115	COG1609	Transcriptional regulator
BHL98_RS02120	COG0840	transmembrane signaling receptor activity
BHL98_RS02135	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BHL98_RS02140	COG2801	Transposase and inactivated derivatives
BHL98_RS02155	COG1785	Belongs to the alkaline phosphatase family
BHL98_RS02200	COG3012	SEC-C Motif Domain Protein
BHL98_RS02210	COG0183	Belongs to the thiolase family
BHL98_RS02215	COG0288	reversible hydration of carbon dioxide
BHL98_RS02230	COG0488	(ABC) transporter
BHL98_RS02235	COG0747	negative chemotaxis
BHL98_RS02245	COG1028	Short-chain dehydrogenase reductase Sdr
BHL98_RS02250	COG4221	oxidoreductase activity
BHL98_RS02255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BHL98_RS02310	COG1024	Enoyl-CoA hydratase
BHL98_RS02330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BHL98_RS02340	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BHL98_RS02355	COG0737	Belongs to the 5'-nucleotidase family
BHL98_RS02360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BHL98_RS02365	COG1127	ABC transporter
BHL98_RS02395	COG1686	Belongs to the peptidase S11 family
BHL98_RS02405	COG2921	Belongs to the UPF0250 family
BHL98_RS02410	COG0583	DNA-binding transcription factor activity
BHL98_RS02450	COG0583	DNA-binding transcription factor activity
BHL98_RS02455	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHL98_RS02455	COG1024	Enoyl-CoA hydratase
BHL98_RS02460	COG1960	acyl-CoA dehydrogenase activity
BHL98_RS02465	COG1960	acyl-CoA dehydrogenase activity
BHL98_RS02470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BHL98_RS02480	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHL98_RS02500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHL98_RS02530	COG2960	long-chain fatty acid transporting porin activity
BHL98_RS02540	COG0004	ammonium transporteR
BHL98_RS02575	COG0519	Catalyzes the synthesis of GMP from XMP
BHL98_RS02575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BHL98_RS02580	COG1902	pentaerythritol trinitrate reductase activity
BHL98_RS02595	COG0642	Histidine kinase
BHL98_RS02615	COG3186	Phenylalanine-4-hydroxylase
BHL98_RS02620	COG1522	sequence-specific DNA binding
BHL98_RS02630	COG0583	DNA-binding transcription factor activity
BHL98_RS02640	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BHL98_RS02660	COG0559	Belongs to the binding-protein-dependent transport system permease family
BHL98_RS02705	COG1192	Involved in chromosome partitioning
BHL98_RS02710	COG1475	DNA binding
BHL98_RS02715	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BHL98_RS02725	COG0356	it plays a direct role in the translocation of protons across the membrane
BHL98_RS02770	COG0318	PFAM AMP-dependent synthetase and ligase
BHL98_RS02775	COG1832	CoA-binding protein
BHL98_RS02790	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BHL98_RS02800	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BHL98_RS02800	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BHL98_RS02800	COG0506	proline dehydrogenase activity
BHL98_RS02815	COG1960	acyl-CoA dehydrogenase activity
BHL98_RS02825	COG0436	Aminotransferase
BHL98_RS02845	COG0277	FAD linked oxidase domain protein
BHL98_RS02855	COG0789	Transcriptional regulator
BHL98_RS02875	COG0668	transmembrane transport
BHL98_RS02895	COG0531	amino acid
BHL98_RS02905	COG4303	Ethanolamine ammonia lyase large subunit
BHL98_RS02910	COG4302	ethanolamine ammonia-lyase activity
BHL98_RS02920	COG1012	belongs to the aldehyde dehydrogenase family
BHL98_RS02945	COG1760	l-serine dehydratase
BHL98_RS02960	COG0509	glycine decarboxylation via glycine cleavage system
BHL98_RS02975	COG0673	inositol 2-dehydrogenase activity
BHL98_RS02990	COG0210	DNA helicase
BHL98_RS02995	COG3245	cytochrome
BHL98_RS03005	COG0582	viral genome integration into host DNA
BHL98_RS03010	COG2801	Transposase and inactivated derivatives
BHL98_RS03015	COG2963	transposase activity
BHL98_RS03020	COG0629	single-stranded DNA binding
BHL98_RS03025	COG2814	Major facilitator Superfamily
BHL98_RS03050	COG1280	lysine exporter protein (LysE YggA)
BHL98_RS03070	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BHL98_RS03085	COG1137	ATPase activity
BHL98_RS03090	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BHL98_RS03095	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BHL98_RS03120	COG1194	a g-specific adenine glycosylase
BHL98_RS03135	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BHL98_RS03150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BHL98_RS03165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BHL98_RS03170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BHL98_RS03180	COG0742	ribosomal rna small subunit methyltransferase
BHL98_RS03190	COG0625	glutathione transferase activity
BHL98_RS03200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BHL98_RS03210	COG0243	molybdopterin cofactor binding
BHL98_RS03215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BHL98_RS03225	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BHL98_RS03235	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BHL98_RS03240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHL98_RS03260	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BHL98_RS03275	COG0587	DNA-directed DNA polymerase activity
BHL98_RS03285	COG2814	Major facilitator Superfamily
BHL98_RS03320	COG2226	methyltransferase
BHL98_RS03330	COG1960	acyl-CoA dehydrogenase activity
BHL98_RS03385	COG0583	DNA-binding transcription factor activity
BHL98_RS03390	COG2188	Transcriptional regulator
BHL98_RS03395	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BHL98_RS03400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BHL98_RS03405	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHL98_RS03405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BHL98_RS03410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHL98_RS03410	COG2190	(PTS) system
BHL98_RS03410	COG1263	PTS System
BHL98_RS03430	COG1294	oxidase, subunit
BHL98_RS03470	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BHL98_RS03475	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BHL98_RS03480	COG2801	Transposase and inactivated derivatives
BHL98_RS03485	COG2963	transposase activity
BHL98_RS03515	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BHL98_RS03560	COG0514	ATP-dependent DNA helicase (RecQ)
BHL98_RS03690	COG0201	protein transport
BHL98_RS03735	COG4232	protein-disulfide reductase activity
BHL98_RS03755	COG1333	cytochrome c biogenesis protein
BHL98_RS03760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BHL98_RS03765	COG2963	transposase activity
BHL98_RS03770	COG2801	Transposase and inactivated derivatives
BHL98_RS03780	COG3047	cAMP biosynthetic process
BHL98_RS03795	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BHL98_RS03805	COG1881	PFAM PEBP family protein
BHL98_RS03810	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BHL98_RS03815	COG0280	phosphate acetyltransferase
BHL98_RS03815	COG0281	malic enzyme
BHL98_RS03835	COG1522	sequence-specific DNA binding
BHL98_RS03855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BHL98_RS03860	COG2151	metal-sulfur cluster biosynthetic enzyme
BHL98_RS03865	COG3396	Phenylacetate-CoA oxygenase
BHL98_RS03870	COG3460	Phenylacetate-CoA oxygenase
BHL98_RS03875	COG3396	Phenylacetate-CoA oxygenase
BHL98_RS03910	COG2963	transposase activity
BHL98_RS03915	COG2801	Transposase and inactivated derivatives
BHL98_RS03930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHL98_RS03940	COG1522	sequence-specific DNA binding
BHL98_RS03945	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BHL98_RS03970	COG2801	Transposase and inactivated derivatives
BHL98_RS03975	COG2963	transposase activity
BHL98_RS03985	COG3397	chitin binding
BHL98_RS04005	COG2267	carboxylic ester hydrolase activity
BHL98_RS04035	COG1280	lysine exporter protein (LysE YggA)
BHL98_RS04060	COG1028	Short-chain dehydrogenase reductase Sdr
BHL98_RS04075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BHL98_RS04110	COG0519	Catalyzes the synthesis of GMP from XMP
BHL98_RS04120	COG0561	phosphatase activity
BHL98_RS04125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BHL98_RS04135	COG0438	transferase activity, transferring glycosyl groups
BHL98_RS04155	COG1360	Flagellar Motor Protein
BHL98_RS04160	COG2201	protein-glutamate methylesterase activity
BHL98_RS04180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BHL98_RS04190	COG2201	protein-glutamate methylesterase activity
BHL98_RS04195	COG0745	RESPONSE REGULATOR receiver
BHL98_RS04200	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BHL98_RS04220	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BHL98_RS04225	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BHL98_RS04250	COG1950	PFAM Membrane protein of
BHL98_RS04255	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BHL98_RS04275	COG2963	transposase activity
BHL98_RS04280	COG2801	Transposase and inactivated derivatives
BHL98_RS04290	COG0142	geranyltranstransferase activity
BHL98_RS04330	COG2095	MarC family integral membrane protein
BHL98_RS04335	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BHL98_RS04340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BHL98_RS04380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHL98_RS04385	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BHL98_RS04400	COG0439	Biotin carboxylase
BHL98_RS04405	COG0511	ligase activity, forming carbon-carbon bonds
BHL98_RS04410	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BHL98_RS04415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHL98_RS04425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BHL98_RS04430	COG3150	esterase
BHL98_RS04435	COG0557	exoribonuclease II activity
BHL98_RS04440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BHL98_RS04445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BHL98_RS04460	COG1414	Transcriptional regulator
BHL98_RS04465	COG3734	2-keto-3-deoxy-galactonokinase
BHL98_RS04475	COG1028	Short-chain dehydrogenase reductase Sdr
BHL98_RS04485	COG1129	ABC transporter
BHL98_RS04490	COG1172	Belongs to the binding-protein-dependent transport system permease family
BHL98_RS04495	COG1028	Short-chain dehydrogenase reductase Sdr
BHL98_RS04505	COG0284	orotidine-5'-phosphate decarboxylase activity
BHL98_RS04510	COG1546	Belongs to the CinA family
BHL98_RS04515	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BHL98_RS04545	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BHL98_RS04555	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BHL98_RS04560	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BHL98_RS04565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BHL98_RS04570	COG2814	Major facilitator Superfamily
BHL98_RS04585	COG0583	DNA-binding transcription factor activity
BHL98_RS04595	COG1301	dicarboxylic acid transport
BHL98_RS04600	COG4266	Belongs to the allantoicase family
BHL98_RS04610	COG0735	belongs to the Fur family
BHL98_RS04615	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BHL98_RS04645	COG1466	dna polymerase III delta subunit
BHL98_RS04650	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BHL98_RS04655	COG1981	membrane
BHL98_RS04660	COG1737	Transcriptional regulator
BHL98_RS04670	COG0800	Aldolase
BHL98_RS04690	COG2223	nitrite transmembrane transporter activity
BHL98_RS04695	COG0583	DNA-binding transcription factor activity
BHL98_RS04700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BHL98_RS04710	COG0765	amino acid transport
BHL98_RS04715	COG0765	amino acid transport
BHL98_RS04720	COG1126	abc transporter atp-binding protein
BHL98_RS04750	COG0121	glutamine amidotransferase
BHL98_RS04755	COG0418	dihydroorotase activity
BHL98_RS04780	COG1017	nitric oxide dioxygenase activity
BHL98_RS04780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BHL98_RS04785	COG2096	Adenosyltransferase
BHL98_RS04790	COG0277	FAD linked oxidase domain protein
BHL98_RS04795	COG0277	FAD linked oxidase domain protein
BHL98_RS04800	COG0277	FAD linked oxidase domain protein
BHL98_RS04805	COG0247	lactate metabolic process
BHL98_RS04820	COG3639	organic phosphonate transmembrane transporter activity
BHL98_RS04830	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BHL98_RS04835	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BHL98_RS04840	COG3454	Phosphonate metabolism
BHL98_RS04845	COG4778	phosphonate C-P lyase system protein PhnL
BHL98_RS04850	COG4107	phosphonate C-P lyase system protein PhnK
BHL98_RS04855	COG3627	carbon phosphorus lyase activity
BHL98_RS04860	COG3626	phosphonate metabolism
BHL98_RS04870	COG3624	Phosphonate C-P lyase system protein PhnG
BHL98_RS04875	COG2188	Transcriptional regulator
BHL98_RS04880	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BHL98_RS04905	COG0783	Belongs to the Dps family
BHL98_RS04925	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BHL98_RS04935	COG0343	queuine tRNA-ribosyltransferase activity
BHL98_RS04940	COG1862	Preprotein translocase
BHL98_RS04945	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BHL98_RS04950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BHL98_RS04960	COG2353	YceI-like domain
BHL98_RS04965	COG2353	YceI-like domain
BHL98_RS04980	COG2995	paraquat-inducible protein a
BHL98_RS04985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BHL98_RS04985	COG3008	intermembrane lipid transfer
BHL98_RS05055	COG0069	glutamate synthase activity
BHL98_RS05060	COG0625	glutathione transferase activity
BHL98_RS05065	COG0006	proline dipeptidase activity
BHL98_RS05070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BHL98_RS05075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BHL98_RS05080	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BHL98_RS05120	COG0588	phosphoglycerate mutase activity
BHL98_RS05130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BHL98_RS05140	COG0625	glutathione transferase activity
BHL98_RS05145	COG0625	glutathione transferase activity
BHL98_RS05150	COG1917	Cupin 2, conserved barrel domain protein
BHL98_RS05150	COG4977	sequence-specific DNA binding
BHL98_RS05175	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BHL98_RS05180	COG0312	modulator of DNA gyrase
BHL98_RS05185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BHL98_RS05190	COG3164	Protein of unknown function
BHL98_RS05195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BHL98_RS05200	COG0497	DNA recombination
BHL98_RS05245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BHL98_RS05255	COG1428	Deoxynucleoside kinase
BHL98_RS05260	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BHL98_RS05265	COG0617	tRNA 3'-terminal CCA addition
BHL98_RS05275	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BHL98_RS05300	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BHL98_RS05305	COG0586	Pfam SNARE associated Golgi protein
BHL98_RS05405	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BHL98_RS05420	COG1368	sulfuric ester hydrolase activity
BHL98_RS05425	COG3321	synthase
BHL98_RS05425	COG1028	Short-chain dehydrogenase reductase Sdr
BHL98_RS05425	COG0604	alcohol dehydrogenase
BHL98_RS05430	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BHL98_RS05435	COG0156	8-amino-7-oxononanoate synthase activity
BHL98_RS05450	COG2963	transposase activity
BHL98_RS05455	COG2801	Transposase and inactivated derivatives
BHL98_RS05460	COG1113	amino acid transport
BHL98_RS05465	COG0542	response to heat
BHL98_RS05475	COG1278	Cold shock
BHL98_RS05500	COG1663	tetraacyldisaccharide 4'-kinase activity
BHL98_RS05505	COG1570	exodeoxyribonuclease VII activity
BHL98_RS05510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BHL98_RS05520	COG2963	transposase activity
BHL98_RS05525	COG2801	Transposase and inactivated derivatives
BHL98_RS05560	COG2814	Major facilitator Superfamily
BHL98_RS05580	COG2188	Transcriptional regulator
BHL98_RS05585	COG0656	L-ascorbic acid biosynthetic process
BHL98_RS05595	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BHL98_RS05605	COG2801	Transposase and inactivated derivatives
BHL98_RS05610	COG2963	transposase activity
BHL98_RS05640	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BHL98_RS05645	COG0196	riboflavin kinase activity
BHL98_RS05650	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BHL98_RS05655	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BHL98_RS05655	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BHL98_RS05660	COG1511	domain protein
BHL98_RS05660	COG3264	Mechanosensitive ion channel
BHL98_RS05685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BHL98_RS05705	COG1047	Peptidyl-prolyl cis-trans
BHL98_RS05710	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BHL98_RS05725	COG2801	Transposase and inactivated derivatives
BHL98_RS05760	COG1773	rubredoxin
BHL98_RS05770	COG0488	(ABC) transporter
BHL98_RS05795	COG0583	DNA-binding transcription factor activity
BHL98_RS05805	COG0583	DNA-binding transcription factor activity
BHL98_RS05810	COG0477	Major facilitator Superfamily
BHL98_RS05850	COG2801	Transposase and inactivated derivatives
BHL98_RS05855	COG2963	transposase activity
BHL98_RS05865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BHL98_RS05890	COG0859	PFAM glycosyl transferase family 9
BHL98_RS05945	COG1129	ABC transporter
BHL98_RS05955	COG0559	Belongs to the binding-protein-dependent transport system permease family
BHL98_RS05965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BHL98_RS05975	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BHL98_RS05985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BHL98_RS06005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BHL98_RS06015	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BHL98_RS06020	COG2226	methyltransferase
BHL98_RS06040	COG0762	integral membrane protein
BHL98_RS06065	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BHL98_RS06075	COG0436	Aminotransferase
BHL98_RS06100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BHL98_RS06100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BHL98_RS06120	COG2814	Major facilitator Superfamily
BHL98_RS06135	COG1126	abc transporter atp-binding protein
BHL98_RS06140	COG0765	amino acid transport
BHL98_RS06145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHL98_RS06155	COG0363	glucosamine-6-phosphate deaminase activity
BHL98_RS06160	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BHL98_RS06170	COG1175	transmembrane transport
BHL98_RS06175	COG0395	ABC-type sugar transport system, permease component
BHL98_RS06180	COG3842	ATPase activity
BHL98_RS06185	COG2860	membrane
BHL98_RS06190	COG1193	negative regulation of DNA recombination
BHL98_RS06195	COG0492	ferredoxin-NADP+ reductase activity
BHL98_RS06200	COG1674	ftsk spoiiie
BHL98_RS06205	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BHL98_RS06210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BHL98_RS06245	COG2894	cell division
BHL98_RS06265	COG0859	PFAM glycosyl transferase family 9
BHL98_RS06275	COG0477	Major facilitator Superfamily
BHL98_RS06300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BHL98_RS06305	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BHL98_RS06315	COG1561	YicC-like family, N-terminal region
BHL98_RS06330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BHL98_RS06355	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BHL98_RS06370	COG2801	Transposase and inactivated derivatives
BHL98_RS06375	COG2963	transposase activity
BHL98_RS06390	COG2885	chlorophyll binding
BHL98_RS06395	COG0823	Involved in the tonB-independent uptake of proteins
BHL98_RS06420	COG4221	oxidoreductase activity
BHL98_RS06475	COG0450	alkyl hydroperoxide reductase
BHL98_RS06485	COG1960	acyl-CoA dehydrogenase activity
BHL98_RS06510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BHL98_RS06520	COG2814	Major facilitator Superfamily
BHL98_RS06540	COG2814	Major facilitator Superfamily
BHL98_RS06545	COG0778	Nitroreductase
BHL98_RS06550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BHL98_RS06555	COG0583	DNA-binding transcription factor activity
BHL98_RS06560	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BHL98_RS06585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BHL98_RS06600	COG4774	siderophore transport
BHL98_RS06605	COG1120	ATPase activity
BHL98_RS06620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHL98_RS06655	COG0730	response to heat
BHL98_RS06665	COG0584	glycerophosphoryl diester phosphodiesterase
BHL98_RS06670	COG1280	lysine exporter protein (LysE YggA)
BHL98_RS06720	COG0604	alcohol dehydrogenase
BHL98_RS06725	COG1733	regulation of RNA biosynthetic process
BHL98_RS06735	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BHL98_RS06750	COG1773	rubredoxin
BHL98_RS06770	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BHL98_RS06845	COG1215	transferase activity, transferring glycosyl groups
BHL98_RS06860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BHL98_RS06870	COG2963	transposase activity
BHL98_RS06875	COG2801	Transposase and inactivated derivatives
BHL98_RS06905	COG0456	acetyltransferase
BHL98_RS06910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BHL98_RS06915	COG0543	2 iron, 2 sulfur cluster binding
BHL98_RS06915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BHL98_RS06930	COG1187	pseudouridine synthase activity
BHL98_RS06940	COG0583	DNA-binding transcription factor activity
BHL98_RS06950	COG2267	carboxylic ester hydrolase activity
BHL98_RS06955	COG2258	MOSC domain
BHL98_RS06960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BHL98_RS06970	COG1396	sequence-specific DNA binding
BHL98_RS06980	COG2801	Transposase and inactivated derivatives
BHL98_RS06985	COG2963	transposase activity
BHL98_RS06990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHL98_RS06995	COG0697	spore germination
BHL98_RS07005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHL98_RS07025	COG4106	trans-aconitate 2-methyltransferase activity
BHL98_RS07040	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BHL98_RS07050	COG3135	benzoate transporter
BHL98_RS07090	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BHL98_RS07095	COG2878	Part of a membrane complex involved in electron transport
BHL98_RS07100	COG1309	transcriptional regulator
BHL98_RS07110	COG3387	PFAM Glycoside hydrolase 15-related
BHL98_RS07115	COG2706	6-phosphogluconolactonase activity
BHL98_RS07120	COG1674	ftsk spoiiie
BHL98_RS07150	COG0513	Belongs to the DEAD box helicase family
BHL98_RS07155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BHL98_RS07195	COG0438	transferase activity, transferring glycosyl groups
BHL98_RS07200	COG0859	PFAM glycosyl transferase family 9
BHL98_RS07235	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BHL98_RS07240	COG1595	DNA-templated transcription, initiation
BHL98_RS07275	COG2233	PERMEase
BHL98_RS07295	COG0799	negative regulation of ribosome biogenesis
BHL98_RS07310	COG0151	Belongs to the GarS family
BHL98_RS07325	COG1028	Short-chain dehydrogenase reductase Sdr
BHL98_RS07345	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BHL98_RS07350	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BHL98_RS07365	COG2205	protein histidine kinase activity
BHL98_RS07370	COG0745	RESPONSE REGULATOR receiver
BHL98_RS07400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BHL98_RS07410	COG0154	amidase activity
BHL98_RS07425	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BHL98_RS07430	COG1028	Short-chain dehydrogenase reductase Sdr
BHL98_RS07450	COG0438	transferase activity, transferring glycosyl groups
BHL98_RS07480	COG0028	Belongs to the TPP enzyme family
BHL98_RS07500	COG1183	phosphatidylcholine synthase activity
BHL98_RS07510	COG0659	secondary active sulfate transmembrane transporter activity
BHL98_RS07515	COG0288	reversible hydration of carbon dioxide
BHL98_RS07525	COG0683	leucine binding
BHL98_RS07540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHL98_RS07540	COG3321	synthase
BHL98_RS07540	COG0604	alcohol dehydrogenase
BHL98_RS07540	COG4221	oxidoreductase activity
BHL98_RS07545	COG0149	triose-phosphate isomerase activity
BHL98_RS07580	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BHL98_RS07590	COG1034	ATP synthesis coupled electron transport
BHL98_RS07625	COG1007	ATP synthesis coupled electron transport
BHL98_RS07645	COG1960	acyl-CoA dehydrogenase activity
BHL98_RS07650	COG1960	acyl-CoA dehydrogenase activity
BHL98_RS07655	COG2030	dehydratase
BHL98_RS07655	COG1012	belongs to the aldehyde dehydrogenase family
BHL98_RS07675	COG1960	acyl-CoA dehydrogenase activity
BHL98_RS07685	COG0588	phosphoglycerate mutase activity
BHL98_RS07690	COG1024	Enoyl-CoA hydratase
BHL98_RS07700	COG0436	Aminotransferase
BHL98_RS07715	COG2866	Carboxypeptidase
BHL98_RS07770	COG1959	2 iron, 2 sulfur cluster binding
BHL98_RS07785	COG1522	sequence-specific DNA binding
BHL98_RS07790	COG3842	ATPase activity
BHL98_RS07795	COG1176	ABC-type spermidine putrescine transport system, permease component I
BHL98_RS07800	COG1840	ABC-type Fe3 transport system, periplasmic component
BHL98_RS07815	COG1289	transmembrane transporter activity
BHL98_RS07825	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BHL98_RS07830	COG1074	ATP-dependent DNA helicase activity
BHL98_RS07835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BHL98_RS07845	COG2200	EAL domain
BHL98_RS07865	COG2963	transposase activity
BHL98_RS07870	COG2801	Transposase and inactivated derivatives
BHL98_RS07895	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BHL98_RS07900	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BHL98_RS07910	COG0697	spore germination
BHL98_RS07915	COG2814	Major facilitator Superfamily
BHL98_RS07935	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BHL98_RS07940	COG3842	ATPase activity
BHL98_RS07945	COG1177	transmembrane transport
BHL98_RS07960	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BHL98_RS07965	COG1840	ABC-type Fe3 transport system, periplasmic component
BHL98_RS07970	COG1609	Transcriptional regulator
BHL98_RS08015	COG1522	sequence-specific DNA binding
BHL98_RS08035	COG0583	DNA-binding transcription factor activity
BHL98_RS08065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHL98_RS08095	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BHL98_RS08100	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHL98_RS08105	COG0583	DNA-binding transcription factor activity
BHL98_RS08125	COG3052	prosthetic group binding
BHL98_RS08145	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BHL98_RS08155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BHL98_RS08175	COG2801	Transposase and inactivated derivatives
BHL98_RS08180	COG2963	transposase activity
BHL98_RS08185	COG2963	transposase activity
BHL98_RS08190	COG2801	Transposase and inactivated derivatives
BHL98_RS08205	COG0477	Major facilitator Superfamily
BHL98_RS08215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BHL98_RS08220	COG0328	RNA-DNA hybrid ribonuclease activity
BHL98_RS08225	COG2226	methyltransferase
BHL98_RS08230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHL98_RS08235	COG0741	lytic transglycosylase activity
BHL98_RS08235	COG1388	LysM domain
BHL98_RS08255	COG0505	Belongs to the CarA family
BHL98_RS08265	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BHL98_RS08270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BHL98_RS08280	COG1534	Rna-binding protein
BHL98_RS08290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BHL98_RS08295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BHL98_RS08305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BHL98_RS08310	COG0573	inorganic phosphate transmembrane transporter activity
BHL98_RS08315	COG0581	inorganic phosphate transmembrane transporter activity
BHL98_RS08330	COG0745	RESPONSE REGULATOR receiver
BHL98_RS08340	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BHL98_RS08405	COG0534	Mate efflux family protein
BHL98_RS08415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BHL98_RS08420	COG4942	peptidase
BHL98_RS08430	COG2963	transposase activity
BHL98_RS08435	COG2801	Transposase and inactivated derivatives
BHL98_RS08460	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BHL98_RS08505	COG0366	Alpha amylase catalytic
BHL98_RS08510	COG0366	Alpha amylase catalytic
BHL98_RS08545	COG0583	DNA-binding transcription factor activity
BHL98_RS08550	COG0745	RESPONSE REGULATOR receiver
BHL98_RS08595	COG0859	PFAM glycosyl transferase family 9
BHL98_RS08595	COG0457	Tetratricopeptide repeat
BHL98_RS08665	COG2801	Transposase and inactivated derivatives
BHL98_RS08670	COG2963	transposase activity
BHL98_RS08685	COG1595	DNA-templated transcription, initiation
BHL98_RS08725	COG0306	phosphate transporter
BHL98_RS08730	COG0791	NLP P60 protein
BHL98_RS08735	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BHL98_RS08740	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BHL98_RS08745	COG0726	polysaccharide deacetylase
BHL98_RS08750	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BHL98_RS08750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BHL98_RS08760	COG0463	Glycosyl transferase, family 2
BHL98_RS08765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BHL98_RS08770	COG2076	Multidrug Resistance protein
BHL98_RS08775	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BHL98_RS08785	COG0436	Aminotransferase
BHL98_RS08805	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BHL98_RS08810	COG0314	molybdopterin synthase activity
BHL98_RS08815	COG2346	COG2346, Truncated hemoglobins
BHL98_RS08820	COG1959	2 iron, 2 sulfur cluster binding
BHL98_RS08825	COG0542	response to heat
BHL98_RS08850	COG0534	Mate efflux family protein
BHL98_RS08865	COG3228	Belongs to the MtfA family
BHL98_RS08870	COG0477	Major facilitator Superfamily
BHL98_RS08875	COG0789	Transcriptional regulator
BHL98_RS08880	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BHL98_RS08900	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BHL98_RS08915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BHL98_RS08960	COG0670	Belongs to the BI1 family
BHL98_RS08995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BHL98_RS09010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BHL98_RS09015	COG0330	HflC and HflK could
BHL98_RS09020	COG0330	HflC and HflK could
BHL98_RS09040	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BHL98_RS09050	COG2183	response to ionizing radiation
BHL98_RS09065	COG1199	ATP-dependent helicase activity
BHL98_RS09075	COG0564	pseudouridine synthase activity
BHL98_RS09085	COG3243	poly(R)-hydroxyalkanoic acid synthase
BHL98_RS09090	COG0183	Belongs to the thiolase family
BHL98_RS09095	COG1028	Short-chain dehydrogenase reductase Sdr
BHL98_RS09115	COG0183	Belongs to the thiolase family
BHL98_RS09125	COG0626	cystathionine gamma-synthase activity
BHL98_RS09130	COG0560	Phosphoserine phosphatase
BHL98_RS09140	COG0390	transport system, permease component
BHL98_RS09145	COG1122	ATPase activity
BHL98_RS09150	COG2982	Protein involved in outer membrane biogenesis
BHL98_RS09155	COG0488	(ABC) transporter
BHL98_RS09170	COG2070	2-Nitropropane dioxygenase
BHL98_RS09175	COG3047	cAMP biosynthetic process
BHL98_RS09185	COG1914	H( )-stimulated, divalent metal cation uptake system
BHL98_RS09190	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BHL98_RS09195	COG3842	ATPase activity
BHL98_RS09200	COG1176	ABC-type spermidine putrescine transport system, permease component I
BHL98_RS09205	COG1177	transmembrane transport
BHL98_RS09215	COG2801	Transposase and inactivated derivatives
BHL98_RS09220	COG2963	transposase activity
BHL98_RS09245	COG4964	Belongs to the GSP D family
BHL98_RS09310	COG0318	PFAM AMP-dependent synthetase and ligase
BHL98_RS09320	COG2814	Major facilitator Superfamily
BHL98_RS09330	COG0519	Catalyzes the synthesis of GMP from XMP
BHL98_RS09355	COG0840	transmembrane signaling receptor activity
BHL98_RS09375	COG0557	exoribonuclease II activity
BHL98_RS09380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BHL98_RS09390	COG3023	N-Acetylmuramoyl-L-alanine amidase
BHL98_RS09400	COG1802	Transcriptional regulator
BHL98_RS09405	COG0673	inositol 2-dehydrogenase activity
BHL98_RS09410	COG2963	transposase activity
BHL98_RS09415	COG2801	Transposase and inactivated derivatives
BHL98_RS09420	COG0477	Major facilitator Superfamily
BHL98_RS09425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHL98_RS09435	COG2816	NAD+ diphosphatase activity
BHL98_RS09450	COG0824	Thioesterase
BHL98_RS09460	COG0411	ABC transporter
BHL98_RS09470	COG3718	enzyme involved in inositol metabolism
BHL98_RS09480	COG3962	Belongs to the TPP enzyme family
BHL98_RS09495	COG1172	Belongs to the binding-protein-dependent transport system permease family
BHL98_RS09510	COG0673	inositol 2-dehydrogenase activity
BHL98_RS09515	COG0673	inositol 2-dehydrogenase activity
BHL98_RS09520	COG0425	Belongs to the sulfur carrier protein TusA family
BHL98_RS09530	COG0745	RESPONSE REGULATOR receiver
BHL98_RS09540	COG5002	protein histidine kinase activity
BHL98_RS09550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BHL98_RS09555	COG0525	valine-tRNA ligase activity
BHL98_RS09560	COG0210	DNA helicase
BHL98_RS09565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BHL98_RS09570	COG2223	nitrite transmembrane transporter activity
BHL98_RS09575	COG0840	transmembrane signaling receptor activity
BHL98_RS09600	COG0583	DNA-binding transcription factor activity
BHL98_RS09615	COG0277	FAD linked oxidase domain protein
BHL98_RS09630	COG1295	ribonuclease BN
BHL98_RS09645	COG0477	Major facilitator Superfamily
BHL98_RS09665	COG2801	Transposase and inactivated derivatives
BHL98_RS09670	COG2801	Transposase and inactivated derivatives
BHL98_RS09675	COG2963	transposase activity
BHL98_RS09690	COG1538	Outer membrane efflux protein
BHL98_RS09695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHL98_RS09710	COG0038	chloride channel
BHL98_RS09715	COG2855	membrane
BHL98_RS09735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHL98_RS09750	COG1609	Transcriptional regulator
BHL98_RS09840	COG0598	Magnesium transport protein CorA
BHL98_RS09865	COG3264	Mechanosensitive ion channel
BHL98_RS09865	COG1196	nuclear chromosome segregation
BHL98_RS09895	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BHL98_RS09910	COG4263	nitrous-oxide reductase activity
BHL98_RS09930	COG0840	transmembrane signaling receptor activity
BHL98_RS09940	COG2376	Dihydroxyacetone kinase
BHL98_RS09955	COG0475	glutathione-regulated potassium exporter activity
BHL98_RS10020	COG3121	Chaperone
BHL98_RS10030	COG2192	nodulation
BHL98_RS10035	COG2963	transposase activity
BHL98_RS10040	COG2801	Transposase and inactivated derivatives
BHL98_RS10070	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BHL98_RS10075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BHL98_RS10080	COG0508	dehydrogenase complex catalyzes the overall conversion of
BHL98_RS10085	COG0567	Dehydrogenase, E1 component
BHL98_RS10090	COG1217	gtp-binding protein TYPA
BHL98_RS10095	COG1846	Transcriptional regulator
BHL98_RS10105	COG1566	PFAM secretion protein HlyD family protein
BHL98_RS10110	COG2814	Major facilitator Superfamily
BHL98_RS10120	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BHL98_RS10135	COG2251	uridine kinase activity
BHL98_RS10135	COG0195	Participates in both transcription termination and antitermination
BHL98_RS10145	COG1187	pseudouridine synthase activity
BHL98_RS10150	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BHL98_RS10155	COG0583	DNA-binding transcription factor activity
BHL98_RS10200	COG2963	transposase activity
BHL98_RS10205	COG2801	Transposase and inactivated derivatives
BHL98_RS10215	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BHL98_RS10245	COG0776	regulation of translation
BHL98_RS10250	COG0072	phenylalanine-tRNA ligase activity
BHL98_RS10250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHL98_RS10270	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BHL98_RS10285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BHL98_RS10290	COG0251	oxidation-reduction process
BHL98_RS10295	COG2267	carboxylic ester hydrolase activity
BHL98_RS10305	COG0583	DNA-binding transcription factor activity
BHL98_RS10320	COG1028	Short-chain dehydrogenase reductase Sdr
BHL98_RS10355	COG1028	Short-chain dehydrogenase reductase Sdr
BHL98_RS10365	COG2801	Transposase and inactivated derivatives
BHL98_RS10370	COG2963	transposase activity
BHL98_RS10375	COG2801	Transposase and inactivated derivatives
BHL98_RS10380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BHL98_RS10395	COG3251	PFAM MbtH domain protein
BHL98_RS10415	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BHL98_RS10420	COG2207	Transcriptional regulator
BHL98_RS10430	COG0835	chemotaxis
BHL98_RS10450	COG0318	PFAM AMP-dependent synthetase and ligase
BHL98_RS10455	COG0477	Major facilitator Superfamily
BHL98_RS10465	COG1732	Glycine betaine
BHL98_RS10470	COG1174	glycine betaine transport
BHL98_RS10475	COG1125	glycine betaine transport
BHL98_RS10480	COG1174	glycine betaine transport
BHL98_RS10495	COG2235	arginine
BHL98_RS10500	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BHL98_RS10520	COG0583	DNA-binding transcription factor activity
BHL98_RS10525	COG0625	glutathione transferase activity
BHL98_RS10540	COG1846	Transcriptional regulator
BHL98_RS10545	COG2807	transmembrane transport
BHL98_RS10550	COG1649	PFAM Uncharacterised BCR, COG1649
BHL98_RS10570	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BHL98_RS10580	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BHL98_RS10600	COG3979	chitinase
BHL98_RS10610	COG0400	carboxylic ester hydrolase activity
BHL98_RS10640	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BHL98_RS10665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BHL98_RS10670	COG4774	siderophore transport
BHL98_RS10675	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BHL98_RS10715	COG1120	ATPase activity
BHL98_RS10740	COG1028	Short-chain dehydrogenase reductase Sdr
BHL98_RS10745	COG1070	Carbohydrate kinase
BHL98_RS10750	COG1063	alcohol dehydrogenase
BHL98_RS10755	COG1172	Belongs to the binding-protein-dependent transport system permease family
BHL98_RS10765	COG1879	ABC-type sugar transport system periplasmic component
BHL98_RS10785	COG2801	Transposase and inactivated derivatives
BHL98_RS10790	COG2963	transposase activity
BHL98_RS10800	COG1132	(ABC) transporter
BHL98_RS10800	COG2375	cellular response to nickel ion
BHL98_RS10810	COG3121	Chaperone
BHL98_RS10820	COG3539	Fimbrial protein
BHL98_RS10830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHL98_RS10840	COG1309	transcriptional regulator
BHL98_RS10845	COG0739	heme binding
BHL98_RS10850	COG0765	amino acid transport
BHL98_RS10855	COG4597	amino acid ABC transporter
BHL98_RS10870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHL98_RS10915	COG4964	Belongs to the GSP D family
BHL98_RS10935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BHL98_RS10940	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BHL98_RS10955	COG0477	Major facilitator Superfamily
BHL98_RS10960	COG2719	SpoVR family
BHL98_RS10965	COG2718	Belongs to the UPF0229 family
BHL98_RS10970	COG2766	serine protein kinase
BHL98_RS10975	COG2801	Transposase and inactivated derivatives
BHL98_RS10980	COG2963	transposase activity
BHL98_RS10985	COG0583	DNA-binding transcription factor activity
BHL98_RS10990	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BHL98_RS10995	COG4208	sulfate ABC transporter
BHL98_RS11000	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BHL98_RS11005	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BHL98_RS11045	COG0701	Predicted permease
BHL98_RS11050	COG0667	Aldo Keto reductase
BHL98_RS11075	COG1301	dicarboxylic acid transport
BHL98_RS11110	COG1116	anion transmembrane transporter activity
BHL98_RS11115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BHL98_RS11170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHL98_RS11175	COG0765	amino acid transport
BHL98_RS11180	COG2801	Transposase and inactivated derivatives
BHL98_RS11185	COG2963	transposase activity
BHL98_RS11205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BHL98_RS11215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BHL98_RS11220	COG1051	belongs to the nudix hydrolase family
BHL98_RS11240	COG1858	cytochrome C peroxidase
BHL98_RS11245	COG3511	phospholipase C
BHL98_RS11255	COG1566	PFAM secretion protein HlyD family protein
BHL98_RS11260	COG2814	Major facilitator Superfamily
BHL98_RS11270	COG1538	Outer membrane efflux protein
BHL98_RS11275	COG2197	response regulator
BHL98_RS11315	COG0583	DNA-binding transcription factor activity
BHL98_RS11320	COG2814	Major facilitator Superfamily
BHL98_RS11345	COG1914	H( )-stimulated, divalent metal cation uptake system
BHL98_RS11355	COG2963	transposase activity
BHL98_RS11360	COG2801	Transposase and inactivated derivatives
BHL98_RS11365	COG0252	asparaginase activity
BHL98_RS11390	COG0438	transferase activity, transferring glycosyl groups
BHL98_RS11415	COG0084	hydrolase, TatD family'
BHL98_RS11420	COG1247	-acetyltransferase
BHL98_RS11435	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BHL98_RS11440	COG0354	folic acid binding
BHL98_RS11455	COG0657	acetylesterase activity
BHL98_RS11460	COG2130	NADP-dependent
BHL98_RS11480	COG0183	Belongs to the thiolase family
BHL98_RS11485	COG1335	isochorismatase
BHL98_RS11490	COG1024	Enoyl-CoA hydratase
BHL98_RS11490	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHL98_RS11495	COG0318	PFAM AMP-dependent synthetase and ligase
BHL98_RS11520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BHL98_RS11530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BHL98_RS11530	COG0047	phosphoribosylformylglycinamidine synthase activity
BHL98_RS11540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHL98_RS11555	COG4181	ATPase activity
BHL98_RS11605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BHL98_RS11630	COG1929	Belongs to the glycerate kinase type-1 family
BHL98_RS11635	COG1846	Transcriptional regulator
BHL98_RS11640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BHL98_RS11675	COG2801	Transposase and inactivated derivatives
BHL98_RS11680	COG2963	transposase activity
BHL98_RS11725	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BHL98_RS11740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BHL98_RS11800	COG4266	Belongs to the allantoicase family
BHL98_RS11805	COG3195	allantoin biosynthetic process
BHL98_RS11805	COG3648	Uricase
BHL98_RS11820	COG1953	Uracil, thiamine, allantoin
BHL98_RS11835	COG1619	proteins homologs of microcin C7 resistance protein MccF
BHL98_RS11890	COG0697	spore germination
BHL98_RS11900	COG2867	negative regulation of translational initiation
BHL98_RS11910	COG0330	HflC and HflK could
BHL98_RS11945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BHL98_RS11985	COG0750	zinc metalloprotease
BHL98_RS12000	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BHL98_RS12025	COG0024	Methionine aminopeptidase
BHL98_RS12035	COG1187	pseudouridine synthase activity
BHL98_RS12040	COG0242	peptide deformylase activity
BHL98_RS12080	COG1393	Belongs to the ArsC family
BHL98_RS12090	COG2890	protein-(glutamine-N5) methyltransferase activity
BHL98_RS12105	COG0386	Belongs to the glutathione peroxidase family
BHL98_RS12110	COG0488	(ABC) transporter
BHL98_RS12130	COG0477	Major facilitator Superfamily
BHL98_RS12135	COG0351	phosphomethylpyrimidine kinase
BHL98_RS12150	COG1573	uracil-dna glycosylase
BHL98_RS12160	COG1214	PFAM Peptidase M22, glycoprotease
BHL98_RS12170	COG0513	Belongs to the DEAD box helicase family
BHL98_RS12180	COG2224	Isocitrate lyase
BHL98_RS12190	COG0583	DNA-binding transcription factor activity
BHL98_RS12200	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BHL98_RS12250	COG1752	Esterase of the alpha-beta hydrolase superfamily
BHL98_RS12255	COG0791	NLP P60 protein
BHL98_RS12260	COG4172	Belongs to the ABC transporter superfamily
BHL98_RS12265	COG4239	(ABC) transporter, permease
BHL98_RS12270	COG4174	ABC transporter (Permease)
BHL98_RS12275	COG4166	transmembrane transport
BHL98_RS12295	COG0243	molybdopterin cofactor binding
BHL98_RS12320	COG0024	Methionine aminopeptidase
BHL98_RS12335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BHL98_RS12355	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BHL98_RS12370	COG3958	Transketolase
BHL98_RS12375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BHL98_RS12395	COG2175	clavaminate synthase activity
BHL98_RS12425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHL98_RS12430	COG2895	sulfate adenylyltransferase (ATP) activity
BHL98_RS12430	COG0529	Catalyzes the synthesis of activated sulfate
BHL98_RS12435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHL98_RS12440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHL98_RS12470	COG0527	aspartate kinase activity
BHL98_RS12475	COG0037	tRNA processing
BHL98_RS12500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BHL98_RS12510	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BHL98_RS12515	COG1045	serine acetyltransferase
BHL98_RS12525	COG0483	inositol monophosphate 1-phosphatase activity
BHL98_RS12555	COG2850	peptidyl-arginine hydroxylation
BHL98_RS12560	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BHL98_RS12565	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BHL98_RS12570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BHL98_RS12580	COG0180	Tryptophanyl-tRNA synthetase
BHL98_RS12585	COG1994	Peptidase M50
BHL98_RS12590	COG0009	L-threonylcarbamoyladenylate synthase
BHL98_RS12595	COG0613	PHP domain protein
BHL98_RS12600	COG0596	Alpha beta hydrolase
BHL98_RS12605	COG2833	Protein of unknown function (DUF455)
BHL98_RS12615	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BHL98_RS12625	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BHL98_RS12650	COG0658	competence protein
BHL98_RS12650	COG2333	competence protein COMEC
BHL98_RS12655	COG0084	hydrolase, TatD family'
BHL98_RS12660	COG1136	(ABC) transporter
BHL98_RS12675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BHL98_RS12695	COG2975	iron-sulfur cluster assembly
BHL98_RS12720	COG0822	iron-sulfur transferase activity
BHL98_RS12725	COG1104	cysteine desulfurase activity
BHL98_RS12735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BHL98_RS12755	COG1414	Transcriptional regulator
BHL98_RS12780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BHL98_RS12785	COG0508	dehydrogenase complex catalyzes the overall conversion of
BHL98_RS12790	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BHL98_RS12800	COG4566	intracellular signal transduction
BHL98_RS12810	COG0339	signal peptide processing
BHL98_RS12815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BHL98_RS12830	COG2223	nitrite transmembrane transporter activity
BHL98_RS12835	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BHL98_RS12840	COG1140	nitrate reductase beta subunit
BHL98_RS12845	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BHL98_RS12850	COG2181	nitrate reductase activity
BHL98_RS12855	COG4585	Histidine kinase
BHL98_RS12860	COG2197	response regulator
BHL98_RS12885	COG0174	glutamine synthetase
BHL98_RS12895	COG1058	Belongs to the CinA family
BHL98_RS12895	COG1546	Belongs to the CinA family
BHL98_RS12915	COG1643	Atp-dependent helicase
BHL98_RS12920	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BHL98_RS12920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BHL98_RS12930	COG0477	Major facilitator Superfamily
BHL98_RS12940	COG1960	acyl-CoA dehydrogenase activity
BHL98_RS12945	COG0583	DNA-binding transcription factor activity
BHL98_RS12960	COG2801	Transposase and inactivated derivatives
BHL98_RS12965	COG2963	transposase activity
BHL98_RS13005	COG1881	PFAM PEBP family protein
BHL98_RS13010	COG2814	Major facilitator Superfamily
BHL98_RS13025	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BHL98_RS13040	COG2801	Transposase and inactivated derivatives
BHL98_RS13045	COG1116	anion transmembrane transporter activity
BHL98_RS13050	COG1176	ABC-type spermidine putrescine transport system, permease component I
BHL98_RS13090	COG4215	(ABC) transporter
BHL98_RS13115	COG0347	Belongs to the P(II) protein family
BHL98_RS13135	COG2827	Endonuclease containing a URI domain
BHL98_RS13140	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BHL98_RS13155	COG2271	Major facilitator Superfamily
BHL98_RS13190	COG2226	methyltransferase
BHL98_RS13225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHL98_RS13250	COG0489	protein tyrosine kinase activity
BHL98_RS13255	COG3047	cAMP biosynthetic process
BHL98_RS13255	COG2885	chlorophyll binding
BHL98_RS13280	COG2911	Protein conserved in bacteria
BHL98_RS13285	COG0729	surface antigen
BHL98_RS13295	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BHL98_RS13310	COG0489	protein tyrosine kinase activity
BHL98_RS13315	COG2259	Doxx family
BHL98_RS13320	COG1492	cobalamin metabolic process
BHL98_RS13340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BHL98_RS13355	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BHL98_RS13360	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BHL98_RS13365	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BHL98_RS13375	COG4206	TonB-dependent receptor
BHL98_RS13410	COG0583	DNA-binding transcription factor activity
BHL98_RS13425	COG4654	Cytochrome c, class I
BHL98_RS13445	COG0795	lipopolysaccharide-transporting ATPase activity
BHL98_RS13460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BHL98_RS13460	COG1648	precorrin-2 dehydrogenase activity
BHL98_RS13465	COG2895	sulfate adenylyltransferase (ATP) activity
BHL98_RS13475	COG0175	sulfate reduction
BHL98_RS13490	COG0583	DNA-binding transcription factor activity
BHL98_RS13510	COG2801	Transposase and inactivated derivatives
BHL98_RS13520	COG0174	glutamine synthetase
BHL98_RS13525	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BHL98_RS13550	COG0402	S-adenosylhomocysteine deaminase activity
BHL98_RS13565	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BHL98_RS13600	COG0529	Catalyzes the synthesis of activated sulfate
BHL98_RS13605	COG0415	Belongs to the DNA photolyase family
BHL98_RS13620	COG2151	metal-sulfur cluster biosynthetic enzyme
BHL98_RS13655	COG3154	lipid carrier protein
BHL98_RS13660	COG0826	peptidase U32
BHL98_RS13665	COG0826	peptidase U32
BHL98_RS13680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BHL98_RS13685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BHL98_RS13690	COG0840	transmembrane signaling receptor activity
BHL98_RS13705	COG0396	ATPase activity
BHL98_RS13715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BHL98_RS13720	COG0822	iron-sulfur transferase activity
BHL98_RS13725	COG2151	metal-sulfur cluster biosynthetic enzyme
BHL98_RS13735	COG1959	2 iron, 2 sulfur cluster binding
BHL98_RS13760	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BHL98_RS13770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHL98_RS13780	COG2988	succinylglutamate desuccinylase activity
BHL98_RS13805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BHL98_RS13825	COG2801	Transposase and inactivated derivatives
BHL98_RS13830	COG2963	transposase activity
BHL98_RS13835	COG3511	phospholipase C
BHL98_RS13845	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BHL98_RS13850	COG0596	Alpha beta hydrolase
BHL98_RS13855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHL98_RS13870	COG3394	polysaccharide catabolic process
BHL98_RS13880	COG2963	transposase activity
BHL98_RS13885	COG2801	Transposase and inactivated derivatives
BHL98_RS13895	COG0683	leucine binding
BHL98_RS13900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHL98_RS13915	COG0438	transferase activity, transferring glycosyl groups
BHL98_RS13920	COG1132	(ABC) transporter
BHL98_RS13925	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BHL98_RS13935	COG1999	signal sequence binding
BHL98_RS13950	COG2153	protein acetylation
BHL98_RS13965	COG0583	DNA-binding transcription factor activity
BHL98_RS13970	COG1956	GAF domain-containing protein
BHL98_RS13990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BHL98_RS14010	COG2204	response regulator
BHL98_RS14025	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BHL98_RS14030	COG1381	Involved in DNA repair and RecF pathway recombination
BHL98_RS14035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BHL98_RS14040	COG0571	ribonuclease III activity
BHL98_RS14045	COG0681	Belongs to the peptidase S26 family
BHL98_RS14060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHL98_RS14065	COG3026	antisigma factor binding
BHL98_RS14085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BHL98_RS14120	COG1399	metal-binding, possibly nucleic acid-binding protein
BHL98_RS14160	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BHL98_RS14170	COG0303	'Molybdopterin
BHL98_RS14185	COG1322	Protein conserved in bacteria
BHL98_RS14205	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BHL98_RS14210	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BHL98_RS14225	COG3045	CreA protein
BHL98_RS14250	COG2501	S4 domain
BHL98_RS14255	COG0534	Mate efflux family protein
BHL98_RS14260	COG2963	transposase activity
BHL98_RS14265	COG2801	Transposase and inactivated derivatives
BHL98_RS14275	COG0114	fumarate hydratase activity
BHL98_RS14290	COG0640	Transcriptional regulator
BHL98_RS14305	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BHL98_RS14335	COG2204	response regulator
BHL98_RS14340	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BHL98_RS14350	COG0312	modulator of DNA gyrase
BHL98_RS14355	COG3028	Belongs to the UPF0307 family
BHL98_RS14360	COG0521	Mo-molybdopterin cofactor biosynthetic process
BHL98_RS14370	COG0501	Belongs to the peptidase M48B family
BHL98_RS14385	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BHL98_RS14465	COG2011	ABC-type metal ion transport system permease component
BHL98_RS14475	COG2267	carboxylic ester hydrolase activity
BHL98_RS14480	COG0123	including yeast histone deacetylase and acetoin utilization protein
BHL98_RS14485	COG2951	lytic endotransglycosylase activity
BHL98_RS14510	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BHL98_RS14520	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BHL98_RS14550	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BHL98_RS14555	COG0077	Prephenate dehydratase
BHL98_RS14555	COG1605	Chorismate mutase
BHL98_RS14560	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BHL98_RS14585	COG0546	phosphoglycolate phosphatase activity
BHL98_RS14595	COG2963	transposase activity
BHL98_RS14600	COG2801	Transposase and inactivated derivatives
BHL98_RS14605	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BHL98_RS14615	COG1910	domain protein
BHL98_RS14630	COG3383	formate dehydrogenase (NAD+) activity
BHL98_RS14655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BHL98_RS14660	COG0154	amidase activity
BHL98_RS14675	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BHL98_RS14680	COG2252	PERMEase
BHL98_RS14685	COG0402	S-adenosylhomocysteine deaminase activity
BHL98_RS14690	COG2119	membrane
BHL98_RS14700	COG0308	aminopeptidase N
BHL98_RS14710	COG0583	DNA-binding transcription factor activity
BHL98_RS14760	COG4772	TonB-dependent receptor
BHL98_RS14780	COG2963	transposase activity
BHL98_RS14785	COG2801	Transposase and inactivated derivatives
BHL98_RS14795	COG2801	Transposase and inactivated derivatives
BHL98_RS14800	COG2963	transposase activity
BHL98_RS14835	COG0728	peptidoglycan biosynthetic process
BHL98_RS14850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BHL98_RS14855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BHL98_RS14865	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BHL98_RS14870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BHL98_RS14875	COG0318	PFAM AMP-dependent synthetase and ligase
BHL98_RS14880	COG4974	Belongs to the 'phage' integrase family
BHL98_RS14890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BHL98_RS14895	COG0802	atpase or kinase
BHL98_RS14900	COG0860	N-Acetylmuramoyl-L-alanine amidase
BHL98_RS14910	COG1741	Belongs to the pirin family
BHL98_RS14915	COG3118	belongs to the thioredoxin family
BHL98_RS14925	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BHL98_RS14935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BHL98_RS14950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BHL98_RS14960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BHL98_RS14965	COG1522	sequence-specific DNA binding
BHL98_RS14985	COG2271	Major facilitator Superfamily
BHL98_RS14995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BHL98_RS15000	COG1012	belongs to the aldehyde dehydrogenase family
BHL98_RS15010	COG0583	DNA-binding transcription factor activity
BHL98_RS15015	COG0246	Mannitol dehydrogenase
BHL98_RS15020	COG1070	Carbohydrate kinase
BHL98_RS15025	COG2390	Transcriptional regulator
BHL98_RS15040	COG0583	DNA-binding transcription factor activity
BHL98_RS15050	COG3842	ATPase activity
BHL98_RS15055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHL98_RS15065	COG1175	transmembrane transport
BHL98_RS15080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHL98_RS15090	COG0735	belongs to the Fur family
BHL98_RS15100	COG1121	(ABC) transporter
BHL98_RS15105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BHL98_RS15110	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BHL98_RS15125	COG1070	Carbohydrate kinase
BHL98_RS15130	COG2233	PERMEase
BHL98_RS15135	COG2963	transposase activity
BHL98_RS15140	COG2801	Transposase and inactivated derivatives
BHL98_RS15170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BHL98_RS15175	COG2137	regulation of response to DNA damage stimulus
BHL98_RS15190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BHL98_RS15195	COG0861	Integral membrane protein TerC family
BHL98_RS15200	COG4969	Belongs to the N-Me-Phe pilin family
BHL98_RS15230	COG2801	Transposase and inactivated derivatives
BHL98_RS15235	COG2963	transposase activity
BHL98_RS15245	COG4783	chaperone-mediated protein folding
BHL98_RS15255	COG0429	hydrolase of the alpha beta-hydrolase fold
BHL98_RS15265	COG0859	PFAM glycosyl transferase family 9
BHL98_RS15290	COG0126	phosphoglycerate kinase activity
BHL98_RS15295	COG0469	pyruvate kinase activity
BHL98_RS15305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BHL98_RS15310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BHL98_RS15315	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BHL98_RS15320	COG0009	L-threonylcarbamoyladenylate synthase
BHL98_RS15350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHL98_RS15375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHL98_RS15380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHL98_RS15395	COG2233	PERMEase
BHL98_RS15400	COG2801	Transposase and inactivated derivatives
BHL98_RS15405	COG2963	transposase activity
BHL98_RS15410	COG0840	transmembrane signaling receptor activity
BHL98_RS15450	COG4948	Mandelate Racemase Muconate Lactonizing
BHL98_RS15470	COG0513	Belongs to the DEAD box helicase family
BHL98_RS15510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BHL98_RS15515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BHL98_RS15525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BHL98_RS15530	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BHL98_RS15535	COG0367	asparagine synthase
BHL98_RS15550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHL98_RS15560	COG1396	sequence-specific DNA binding
BHL98_RS15565	COG2814	Major facilitator Superfamily
BHL98_RS15570	COG0583	DNA-binding transcription factor activity
BHL98_RS15580	COG1702	phosphate starvation-inducible protein PhoH
BHL98_RS15590	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BHL98_RS15600	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BHL98_RS15605	COG0752	glycyl-tRNA synthetase alpha subunit
BHL98_RS15610	COG0751	glycine-tRNA ligase activity
BHL98_RS15615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BHL98_RS15620	COG0204	Acyl-transferase
BHL98_RS15645	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BHL98_RS15650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BHL98_RS15665	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BHL98_RS15675	COG5265	(ABC) transporter
BHL98_RS15690	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BHL98_RS15695	COG1024	Enoyl-CoA hydratase
BHL98_RS15700	COG0183	Belongs to the thiolase family
BHL98_RS15705	COG1024	Enoyl-CoA hydratase
BHL98_RS15705	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHL98_RS15710	COG1960	acyl-CoA dehydrogenase activity
BHL98_RS15725	COG0494	nUDIX hydrolase
BHL98_RS15790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BHL98_RS15800	COG0251	oxidation-reduction process
BHL98_RS15805	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BHL98_RS15830	COG0477	Major facilitator Superfamily
BHL98_RS15855	COG0708	Exodeoxyribonuclease III
BHL98_RS15860	COG2326	polyphosphate kinase activity
BHL98_RS15880	COG1077	Cell shape determining protein MreB Mrl
BHL98_RS15895	COG0768	penicillin binding
BHL98_RS15900	COG0772	Belongs to the SEDS family
BHL98_RS15915	COG0720	synthase
BHL98_RS15920	COG0602	queuosine metabolic process
BHL98_RS15935	COG2204	response regulator
BHL98_RS15940	COG5000	phosphorelay sensor kinase activity
BHL98_RS15950	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BHL98_RS15950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BHL98_RS15965	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BHL98_RS15970	COG0242	peptide deformylase activity
BHL98_RS15975	COG0758	DNA mediated transformation
BHL98_RS15990	COG0583	DNA-binding transcription factor activity
BHL98_RS15995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BHL98_RS16020	COG2963	transposase activity
BHL98_RS16025	COG2801	Transposase and inactivated derivatives
BHL98_RS16040	COG4695	Portal protein
BHL98_RS16050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BHL98_RS16065	COG0583	DNA-binding transcription factor activity
BHL98_RS16085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHL98_RS16100	COG2169	Transcriptional regulator
BHL98_RS16100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BHL98_RS16115	COG2963	transposase activity
BHL98_RS16120	COG2801	Transposase and inactivated derivatives
BHL98_RS16860	COG1024	Enoyl-CoA hydratase
BHL98_RS16860	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHL98_RS16865	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHL98_RS16865	COG1024	Enoyl-CoA hydratase
BHL98_RS17620	COG0523	cobalamin synthesis protein
BHL98_RS17645	COG1560	Kdo2-lipid A biosynthetic process
BHL98_RS17930	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BHL98_RS18270	COG0183	Belongs to the thiolase family
BHL98_RS18345	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BHL98_RS18380	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BHL98_RS18500	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHL98_RS18935	COG4303	Ethanolamine ammonia lyase large subunit
BHL98_RS19145	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BHL98_RS20250	COG1414	Transcriptional regulator
BHL98_RS20325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BHL98_RS20710	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BHL98_RS20820	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BHL98_RS21905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BHL98_RS22015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BHL98_RS22490	COG2706	6-phosphogluconolactonase activity
BHL98_RS23200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BHL98_RS23550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BHL98_RS23710	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BHL98_RS23755	COG1640	4-alpha-glucanotransferase
BHL98_RS23820	COG0366	Alpha amylase catalytic
BHL98_RS23905	COG0859	PFAM glycosyl transferase family 9
BHL98_RS23905	COG0457	Tetratricopeptide repeat
BHL98_RS24165	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BHL98_RS24300	COG1199	ATP-dependent helicase activity
BHL98_RS24545	COG2814	Major facilitator Superfamily
BHL98_RS24695	COG3962	Belongs to the TPP enzyme family
BHL98_RS24755	COG0525	valine-tRNA ligase activity
BHL98_RS24930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BHL98_RS25240	COG0567	Dehydrogenase, E1 component
BHL98_RS25310	COG0195	Participates in both transcription termination and antitermination
BHL98_RS25310	COG2251	uridine kinase activity