locus-tag	class	description
NW98_RS00010	COG0592	DNA-directed DNA polymerase activity
NW98_RS00030	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NW98_RS00115	COG0235	Class ii aldolase
NW98_RS00130	COG5002	protein histidine kinase activity
NW98_RS00130	COG5001	Diguanylate cyclase
NW98_RS00175	COG2204	response regulator
NW98_RS00195	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NW98_RS00205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NW98_RS00225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NW98_RS00230	COG1596	polysaccharide export
NW98_RS00270	COG1917	Cupin 2, conserved barrel domain protein
NW98_RS00270	COG4977	sequence-specific DNA binding
NW98_RS00275	COG0625	glutathione transferase activity
NW98_RS00280	COG0625	glutathione transferase activity
NW98_RS00295	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NW98_RS00305	COG0588	phosphoglycerate mutase activity
NW98_RS00345	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NW98_RS00350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NW98_RS00355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NW98_RS00360	COG0006	proline dipeptidase activity
NW98_RS00370	COG0625	glutathione transferase activity
NW98_RS00380	COG0069	glutamate synthase activity
NW98_RS00465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NW98_RS00465	COG3008	intermembrane lipid transfer
NW98_RS00470	COG2995	paraquat-inducible protein a
NW98_RS00490	COG2353	YceI-like domain
NW98_RS00495	COG2353	YceI-like domain
NW98_RS00510	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NW98_RS00515	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NW98_RS00520	COG1862	Preprotein translocase
NW98_RS00525	COG0343	queuine tRNA-ribosyltransferase activity
NW98_RS00540	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NW98_RS00565	COG0783	Belongs to the Dps family
NW98_RS00590	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
NW98_RS00595	COG2188	Transcriptional regulator
NW98_RS00605	COG3624	Phosphonate C-P lyase system protein PhnG
NW98_RS00615	COG3626	phosphonate metabolism
NW98_RS00620	COG3627	carbon phosphorus lyase activity
NW98_RS00625	COG4107	phosphonate C-P lyase system protein PhnK
NW98_RS00630	COG4778	phosphonate C-P lyase system protein PhnL
NW98_RS00635	COG3454	Phosphonate metabolism
NW98_RS00640	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NW98_RS00650	COG3639	organic phosphonate transmembrane transporter activity
NW98_RS00675	COG0247	lactate metabolic process
NW98_RS00680	COG0277	FAD linked oxidase domain protein
NW98_RS00685	COG0277	FAD linked oxidase domain protein
NW98_RS00690	COG0277	FAD linked oxidase domain protein
NW98_RS00695	COG2096	Adenosyltransferase
NW98_RS00700	COG1017	nitric oxide dioxygenase activity
NW98_RS00700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NW98_RS00725	COG0418	dihydroorotase activity
NW98_RS00735	COG0121	glutamine amidotransferase
NW98_RS00785	COG1126	abc transporter atp-binding protein
NW98_RS00790	COG0765	amino acid transport
NW98_RS00795	COG0765	amino acid transport
NW98_RS00800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NW98_RS00805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NW98_RS00815	COG0583	DNA-binding transcription factor activity
NW98_RS00820	COG2223	nitrite transmembrane transporter activity
NW98_RS00845	COG0800	Aldolase
NW98_RS00860	COG1737	Transcriptional regulator
NW98_RS00870	COG1981	membrane
NW98_RS00875	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NW98_RS00880	COG1466	dna polymerase III delta subunit
NW98_RS00910	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NW98_RS00915	COG0735	belongs to the Fur family
NW98_RS00925	COG4266	Belongs to the allantoicase family
NW98_RS00940	COG0629	single-stranded DNA binding
NW98_RS00945	COG2814	Major facilitator Superfamily
NW98_RS00980	COG1280	lysine exporter protein (LysE YggA)
NW98_RS01005	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NW98_RS01020	COG1137	ATPase activity
NW98_RS01025	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NW98_RS01035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NW98_RS01060	COG1194	a g-specific adenine glycosylase
NW98_RS01075	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NW98_RS01090	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NW98_RS01105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NW98_RS01110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NW98_RS01125	COG0742	ribosomal rna small subunit methyltransferase
NW98_RS01135	COG0625	glutathione transferase activity
NW98_RS01145	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NW98_RS01155	COG0243	molybdopterin cofactor binding
NW98_RS01160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NW98_RS01175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NW98_RS01185	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NW98_RS01195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NW98_RS01220	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NW98_RS01235	COG0587	DNA-directed DNA polymerase activity
NW98_RS01245	COG2814	Major facilitator Superfamily
NW98_RS01280	COG2226	methyltransferase
NW98_RS01290	COG1960	acyl-CoA dehydrogenase activity
NW98_RS01345	COG0583	DNA-binding transcription factor activity
NW98_RS01355	COG2188	Transcriptional regulator
NW98_RS01360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NW98_RS01365	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NW98_RS01370	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NW98_RS01370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NW98_RS01375	COG1263	PTS System
NW98_RS01375	COG2190	(PTS) system
NW98_RS01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NW98_RS01400	COG1294	oxidase, subunit
NW98_RS01430	COG0531	amino acid
NW98_RS01450	COG0668	transmembrane transport
NW98_RS01470	COG0789	Transcriptional regulator
NW98_RS01480	COG0277	FAD linked oxidase domain protein
NW98_RS01500	COG0436	Aminotransferase
NW98_RS01520	COG1960	acyl-CoA dehydrogenase activity
NW98_RS01535	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NW98_RS01535	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NW98_RS01535	COG0506	proline dehydrogenase activity
NW98_RS01555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NW98_RS01575	COG1832	CoA-binding protein
NW98_RS01595	COG0318	PFAM AMP-dependent synthetase and ligase
NW98_RS01635	COG0356	it plays a direct role in the translocation of protons across the membrane
NW98_RS01650	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NW98_RS01655	COG1475	DNA binding
NW98_RS01660	COG1192	Involved in chromosome partitioning
NW98_RS01705	COG0559	Belongs to the binding-protein-dependent transport system permease family
NW98_RS01735	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NW98_RS01745	COG0583	DNA-binding transcription factor activity
NW98_RS01760	COG1522	sequence-specific DNA binding
NW98_RS01765	COG3186	Phenylalanine-4-hydroxylase
NW98_RS01785	COG0642	Histidine kinase
NW98_RS01805	COG1902	pentaerythritol trinitrate reductase activity
NW98_RS01810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NW98_RS01810	COG0519	Catalyzes the synthesis of GMP from XMP
NW98_RS01870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NW98_RS01880	COG1522	sequence-specific DNA binding
NW98_RS01885	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NW98_RS01935	COG3397	chitin binding
NW98_RS01960	COG2267	carboxylic ester hydrolase activity
NW98_RS02005	COG1280	lysine exporter protein (LysE YggA)
NW98_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS02050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NW98_RS02095	COG0519	Catalyzes the synthesis of GMP from XMP
NW98_RS02105	COG0561	phosphatase activity
NW98_RS02110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NW98_RS02130	COG0438	transferase activity, transferring glycosyl groups
NW98_RS02160	COG2201	protein-glutamate methylesterase activity
NW98_RS02180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NW98_RS02190	COG2201	protein-glutamate methylesterase activity
NW98_RS02200	COG0745	RESPONSE REGULATOR receiver
NW98_RS02205	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NW98_RS02225	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NW98_RS02230	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NW98_RS02260	COG1950	PFAM Membrane protein of
NW98_RS02265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NW98_RS02395	COG0308	aminopeptidase N
NW98_RS02475	COG0443	Heat shock 70 kDa protein
NW98_RS02500	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NW98_RS02505	COG2823	Periplasmic or secreted lipoprotein
NW98_RS02520	COG1113	amino acid transport
NW98_RS02540	COG1278	Cold shock
NW98_RS02585	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NW98_RS02595	COG1175	transmembrane transport
NW98_RS02600	COG0395	ABC-type sugar transport system, permease component
NW98_RS02605	COG3842	ATPase activity
NW98_RS02610	COG0584	glycerophosphoryl diester phosphodiesterase
NW98_RS02625	COG0070	glutamate synthase
NW98_RS02625	COG0069	glutamate synthase activity
NW98_RS02625	COG0067	glutamate synthase
NW98_RS02640	COG1115	amino acid carrier protein
NW98_RS02650	COG4178	(ABC) transporter
NW98_RS02675	COG1127	ABC transporter
NW98_RS02680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NW98_RS02685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NW98_RS02710	COG1131	(ABC) transporter
NW98_RS02715	COG0842	Transport permease protein
NW98_RS02725	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NW98_RS02735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NW98_RS02740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NW98_RS02750	COG2095	MarC family integral membrane protein
NW98_RS02795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NW98_RS02800	COG0805	protein transport
NW98_RS02810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NW98_RS02815	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NW98_RS02820	COG0723	plastoquinol--plastocyanin reductase activity
NW98_RS02825	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NW98_RS02830	COG2857	Cytochrome c1
NW98_RS02835	COG0625	glutathione transferase activity
NW98_RS02840	COG2969	positive regulation of protein catabolic process
NW98_RS02855	COG4695	Portal protein
NW98_RS02860	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NW98_RS02865	COG3657	addiction module killer protein
NW98_RS02880	COG1987	bacterial-type flagellum assembly
NW98_RS02890	COG0789	Transcriptional regulator
NW98_RS02895	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NW98_RS02895	COG4106	trans-aconitate 2-methyltransferase activity
NW98_RS02905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NW98_RS02915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NW98_RS02930	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS02955	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS03030	COG1695	Transcriptional regulator
NW98_RS03070	COG1960	acyl-CoA dehydrogenase activity
NW98_RS03080	COG0183	Belongs to the thiolase family
NW98_RS03085	COG1024	Enoyl-CoA hydratase
NW98_RS03085	COG1250	3-hydroxyacyl-CoA dehydrogenase
NW98_RS03095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NW98_RS03135	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NW98_RS03155	COG1346	cytolysis
NW98_RS03165	COG0583	DNA-binding transcription factor activity
NW98_RS03175	COG1846	Transcriptional regulator
NW98_RS03220	COG2165	general secretion pathway protein
NW98_RS03240	COG1459	type II secretion system
NW98_RS03265	COG0523	cobalamin synthesis protein
NW98_RS03300	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NW98_RS03305	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NW98_RS03340	COG0583	DNA-binding transcription factor activity
NW98_RS03355	COG2814	Major facilitator Superfamily
NW98_RS03365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NW98_RS03370	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NW98_RS03375	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NW98_RS03385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NW98_RS03415	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NW98_RS03420	COG1546	Belongs to the CinA family
NW98_RS03425	COG0284	orotidine-5'-phosphate decarboxylase activity
NW98_RS03435	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS03440	COG1172	Belongs to the binding-protein-dependent transport system permease family
NW98_RS03445	COG1129	ABC transporter
NW98_RS03455	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS03465	COG3734	2-keto-3-deoxy-galactonokinase
NW98_RS03470	COG1414	Transcriptional regulator
NW98_RS03490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NW98_RS03495	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NW98_RS03500	COG0557	exoribonuclease II activity
NW98_RS03505	COG3150	esterase
NW98_RS03510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NW98_RS03520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NW98_RS03525	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NW98_RS03530	COG0511	ligase activity, forming carbon-carbon bonds
NW98_RS03535	COG0439	Biotin carboxylase
NW98_RS03550	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NW98_RS03555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NW98_RS03610	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NW98_RS03615	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NW98_RS03620	COG2095	MarC family integral membrane protein
NW98_RS03670	COG0142	geranyltranstransferase activity
NW98_RS03695	COG4536	flavin adenine dinucleotide binding
NW98_RS03700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NW98_RS03710	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NW98_RS03725	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NW98_RS03730	COG0494	nUDIX hydrolase
NW98_RS03740	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NW98_RS03765	COG0678	peroxiredoxin activity
NW98_RS03785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NW98_RS03820	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NW98_RS03825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NW98_RS03835	COG3116	cell division
NW98_RS03855	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS03905	COG1024	Enoyl-CoA hydratase
NW98_RS03930	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NW98_RS03940	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NW98_RS03955	COG0737	Belongs to the 5'-nucleotidase family
NW98_RS03960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NW98_RS03965	COG1127	ABC transporter
NW98_RS04000	COG1686	Belongs to the peptidase S11 family
NW98_RS04010	COG2921	Belongs to the UPF0250 family
NW98_RS04015	COG0583	DNA-binding transcription factor activity
NW98_RS04060	COG1250	3-hydroxyacyl-CoA dehydrogenase
NW98_RS04060	COG1024	Enoyl-CoA hydratase
NW98_RS04065	COG1960	acyl-CoA dehydrogenase activity
NW98_RS04070	COG1960	acyl-CoA dehydrogenase activity
NW98_RS04075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NW98_RS04085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NW98_RS04105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NW98_RS04145	COG2960	long-chain fatty acid transporting porin activity
NW98_RS04155	COG0004	ammonium transporteR
NW98_RS04240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS04260	COG2824	Alkylphosphonate utilization operon protein PhnA
NW98_RS04295	COG2233	PERMEase
NW98_RS04305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NW98_RS04315	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NW98_RS04325	COG1706	bacterial-type flagellum-dependent cell motility
NW98_RS04330	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NW98_RS04345	COG1749	Flagellar hook protein flgE
NW98_RS04350	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NW98_RS04355	COG1558	bacterial-type flagellum-dependent cell motility
NW98_RS04360	COG1815	bacterial-type flagellum-dependent cell motility
NW98_RS04375	COG2747	anti-sigma28 factor FlgM
NW98_RS04420	COG0741	lytic transglycosylase activity
NW98_RS04425	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NW98_RS04435	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NW98_RS04440	COG1984	allophanate hydrolase subunit 2
NW98_RS04470	COG4608	Belongs to the ABC transporter superfamily
NW98_RS04475	COG0444	Belongs to the ABC transporter superfamily
NW98_RS04485	COG0601	transmembrane transport
NW98_RS04490	COG0747	negative chemotaxis
NW98_RS04510	COG0579	oxidoreductase
NW98_RS04530	COG3568	Endonuclease Exonuclease Phosphatase
NW98_RS04535	COG1280	lysine exporter protein (LysE YggA)
NW98_RS04555	COG0531	amino acid
NW98_RS04570	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NW98_RS04645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NW98_RS04655	COG2814	Major facilitator Superfamily
NW98_RS04675	COG0667	Aldo Keto reductase
NW98_RS04705	COG1560	Kdo2-lipid A biosynthetic process
NW98_RS04720	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NW98_RS04730	COG0523	cobalamin synthesis protein
NW98_RS04760	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NW98_RS04785	COG1309	transcriptional regulator
NW98_RS04800	COG2814	Major facilitator Superfamily
NW98_RS04810	COG2207	Transcriptional regulator
NW98_RS04825	COG1064	alcohol dehydrogenase
NW98_RS04845	COG0189	ligase activity
NW98_RS04855	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NW98_RS04860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NW98_RS04870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NW98_RS04875	COG0793	Belongs to the peptidase S41A family
NW98_RS04885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NW98_RS04905	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NW98_RS04920	COG1040	competence protein
NW98_RS04925	COG2226	methyltransferase
NW98_RS04940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NW98_RS04950	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NW98_RS04980	COG1612	heme a metabolic process
NW98_RS04990	COG1999	signal sequence binding
NW98_RS05000	COG0840	transmembrane signaling receptor activity
NW98_RS05020	COG4303	Ethanolamine ammonia lyase large subunit
NW98_RS05025	COG4302	ethanolamine ammonia-lyase activity
NW98_RS05035	COG1012	belongs to the aldehyde dehydrogenase family
NW98_RS05065	COG1760	l-serine dehydratase
NW98_RS05085	COG0509	glycine decarboxylation via glycine cleavage system
NW98_RS05100	COG0673	inositol 2-dehydrogenase activity
NW98_RS05120	COG0210	DNA helicase
NW98_RS05125	COG3245	cytochrome
NW98_RS05135	COG0582	viral genome integration into host DNA
NW98_RS05170	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NW98_RS05220	COG0514	ATP-dependent DNA helicase (RecQ)
NW98_RS05350	COG0201	protein transport
NW98_RS05395	COG4232	protein-disulfide reductase activity
NW98_RS05415	COG1333	cytochrome c biogenesis protein
NW98_RS05420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NW98_RS05445	COG3047	cAMP biosynthetic process
NW98_RS05465	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NW98_RS05480	COG1881	PFAM PEBP family protein
NW98_RS05485	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NW98_RS05495	COG0280	phosphate acetyltransferase
NW98_RS05495	COG0281	malic enzyme
NW98_RS05530	COG1522	sequence-specific DNA binding
NW98_RS05550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NW98_RS05560	COG3396	Phenylacetate-CoA oxygenase
NW98_RS05565	COG3460	Phenylacetate-CoA oxygenase
NW98_RS05570	COG3396	Phenylacetate-CoA oxygenase
NW98_RS05635	COG1959	2 iron, 2 sulfur cluster binding
NW98_RS05660	COG1522	sequence-specific DNA binding
NW98_RS05665	COG3842	ATPase activity
NW98_RS05670	COG1176	ABC-type spermidine putrescine transport system, permease component I
NW98_RS05675	COG1840	ABC-type Fe3 transport system, periplasmic component
NW98_RS05700	COG1289	transmembrane transporter activity
NW98_RS05710	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NW98_RS05715	COG1074	ATP-dependent DNA helicase activity
NW98_RS05720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NW98_RS05780	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
NW98_RS05785	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NW98_RS05800	COG0697	spore germination
NW98_RS05810	COG2814	Major facilitator Superfamily
NW98_RS05840	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NW98_RS05850	COG3842	ATPase activity
NW98_RS05855	COG1177	transmembrane transport
NW98_RS05870	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NW98_RS05875	COG1840	ABC-type Fe3 transport system, periplasmic component
NW98_RS05880	COG1609	Transcriptional regulator
NW98_RS05945	COG1522	sequence-specific DNA binding
NW98_RS05970	COG0583	DNA-binding transcription factor activity
NW98_RS06005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NW98_RS06050	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NW98_RS06055	COG1250	3-hydroxyacyl-CoA dehydrogenase
NW98_RS06065	COG0583	DNA-binding transcription factor activity
NW98_RS06090	COG3052	prosthetic group binding
NW98_RS06110	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
NW98_RS06120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NW98_RS06160	COG0477	Major facilitator Superfamily
NW98_RS06175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NW98_RS06180	COG0328	RNA-DNA hybrid ribonuclease activity
NW98_RS06185	COG2226	methyltransferase
NW98_RS06190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NW98_RS06195	COG1388	LysM domain
NW98_RS06195	COG0741	lytic transglycosylase activity
NW98_RS06225	COG0505	Belongs to the CarA family
NW98_RS06235	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NW98_RS06240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NW98_RS06250	COG1534	Rna-binding protein
NW98_RS06260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NW98_RS06265	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NW98_RS06280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NW98_RS06285	COG0573	inorganic phosphate transmembrane transporter activity
NW98_RS06290	COG0581	inorganic phosphate transmembrane transporter activity
NW98_RS06305	COG0745	RESPONSE REGULATOR receiver
NW98_RS06320	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NW98_RS06400	COG0534	Mate efflux family protein
NW98_RS06410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NW98_RS06415	COG4942	peptidase
NW98_RS06455	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NW98_RS06505	COG0366	Alpha amylase catalytic
NW98_RS06510	COG0366	Alpha amylase catalytic
NW98_RS06560	COG0583	DNA-binding transcription factor activity
NW98_RS06565	COG0745	RESPONSE REGULATOR receiver
NW98_RS06610	COG0859	PFAM glycosyl transferase family 9
NW98_RS06610	COG0457	Tetratricopeptide repeat
NW98_RS06710	COG1914	H( )-stimulated, divalent metal cation uptake system
NW98_RS06750	COG2814	Major facilitator Superfamily
NW98_RS06760	COG0583	DNA-binding transcription factor activity
NW98_RS06815	COG2197	response regulator
NW98_RS06830	COG2814	Major facilitator Superfamily
NW98_RS06840	COG1566	PFAM secretion protein HlyD family protein
NW98_RS06855	COG3511	phospholipase C
NW98_RS06860	COG1858	cytochrome C peroxidase
NW98_RS06890	COG1051	belongs to the nudix hydrolase family
NW98_RS06900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NW98_RS06910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NW98_RS06965	COG2816	NAD+ diphosphatase activity
NW98_RS06990	COG0824	Thioesterase
NW98_RS07000	COG0411	ABC transporter
NW98_RS07010	COG3718	enzyme involved in inositol metabolism
NW98_RS07020	COG3962	Belongs to the TPP enzyme family
NW98_RS07035	COG1172	Belongs to the binding-protein-dependent transport system permease family
NW98_RS07050	COG0673	inositol 2-dehydrogenase activity
NW98_RS07055	COG0673	inositol 2-dehydrogenase activity
NW98_RS07065	COG0425	Belongs to the sulfur carrier protein TusA family
NW98_RS07075	COG0745	RESPONSE REGULATOR receiver
NW98_RS07085	COG5002	protein histidine kinase activity
NW98_RS07095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NW98_RS07100	COG0525	valine-tRNA ligase activity
NW98_RS07105	COG0210	DNA helicase
NW98_RS07110	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NW98_RS07115	COG2223	nitrite transmembrane transporter activity
NW98_RS07120	COG0840	transmembrane signaling receptor activity
NW98_RS07155	COG0583	DNA-binding transcription factor activity
NW98_RS07170	COG0277	FAD linked oxidase domain protein
NW98_RS07185	COG1295	ribonuclease BN
NW98_RS07235	COG2801	Transposase and inactivated derivatives
NW98_RS07250	COG1914	H( )-stimulated, divalent metal cation uptake system
NW98_RS07290	COG2814	Major facilitator Superfamily
NW98_RS07300	COG0583	DNA-binding transcription factor activity
NW98_RS07355	COG2197	response regulator
NW98_RS07370	COG2814	Major facilitator Superfamily
NW98_RS07380	COG1566	PFAM secretion protein HlyD family protein
NW98_RS07395	COG3511	phospholipase C
NW98_RS07400	COG1858	cytochrome C peroxidase
NW98_RS07430	COG1051	belongs to the nudix hydrolase family
NW98_RS07440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NW98_RS07450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NW98_RS07505	COG2816	NAD+ diphosphatase activity
NW98_RS07530	COG0824	Thioesterase
NW98_RS07540	COG0411	ABC transporter
NW98_RS07550	COG3718	enzyme involved in inositol metabolism
NW98_RS07560	COG3962	Belongs to the TPP enzyme family
NW98_RS07575	COG1172	Belongs to the binding-protein-dependent transport system permease family
NW98_RS07590	COG0673	inositol 2-dehydrogenase activity
NW98_RS07595	COG0673	inositol 2-dehydrogenase activity
NW98_RS07605	COG0425	Belongs to the sulfur carrier protein TusA family
NW98_RS07615	COG0745	RESPONSE REGULATOR receiver
NW98_RS07625	COG5002	protein histidine kinase activity
NW98_RS07635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NW98_RS07640	COG0525	valine-tRNA ligase activity
NW98_RS07645	COG0210	DNA helicase
NW98_RS07650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NW98_RS07655	COG2223	nitrite transmembrane transporter activity
NW98_RS07660	COG0840	transmembrane signaling receptor activity
NW98_RS07695	COG0583	DNA-binding transcription factor activity
NW98_RS07710	COG0277	FAD linked oxidase domain protein
NW98_RS07725	COG1295	ribonuclease BN
NW98_RS07775	COG2801	Transposase and inactivated derivatives
NW98_RS07790	COG1914	H( )-stimulated, divalent metal cation uptake system
NW98_RS07830	COG2814	Major facilitator Superfamily
NW98_RS07840	COG0583	DNA-binding transcription factor activity
NW98_RS07895	COG2197	response regulator
NW98_RS07910	COG2814	Major facilitator Superfamily
NW98_RS07920	COG1566	PFAM secretion protein HlyD family protein
NW98_RS07935	COG3511	phospholipase C
NW98_RS07940	COG1858	cytochrome C peroxidase
NW98_RS07970	COG1051	belongs to the nudix hydrolase family
NW98_RS07980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NW98_RS07990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NW98_RS08045	COG2816	NAD+ diphosphatase activity
NW98_RS08070	COG0824	Thioesterase
NW98_RS08080	COG0411	ABC transporter
NW98_RS08090	COG3718	enzyme involved in inositol metabolism
NW98_RS08100	COG3962	Belongs to the TPP enzyme family
NW98_RS08115	COG1172	Belongs to the binding-protein-dependent transport system permease family
NW98_RS08130	COG0673	inositol 2-dehydrogenase activity
NW98_RS08135	COG0673	inositol 2-dehydrogenase activity
NW98_RS08145	COG0425	Belongs to the sulfur carrier protein TusA family
NW98_RS08155	COG0745	RESPONSE REGULATOR receiver
NW98_RS08165	COG5002	protein histidine kinase activity
NW98_RS08175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NW98_RS08180	COG0525	valine-tRNA ligase activity
NW98_RS08185	COG0210	DNA helicase
NW98_RS08190	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NW98_RS08195	COG2223	nitrite transmembrane transporter activity
NW98_RS08200	COG0840	transmembrane signaling receptor activity
NW98_RS08235	COG0583	DNA-binding transcription factor activity
NW98_RS08315	COG2801	Transposase and inactivated derivatives
NW98_RS08330	COG2192	nodulation
NW98_RS08345	COG2801	Transposase and inactivated derivatives
NW98_RS08385	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NW98_RS08390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NW98_RS08395	COG0508	dehydrogenase complex catalyzes the overall conversion of
NW98_RS08400	COG0567	Dehydrogenase, E1 component
NW98_RS08405	COG1217	gtp-binding protein TYPA
NW98_RS08415	COG1846	Transcriptional regulator
NW98_RS08425	COG1566	PFAM secretion protein HlyD family protein
NW98_RS08430	COG2814	Major facilitator Superfamily
NW98_RS08440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NW98_RS08455	COG0195	Participates in both transcription termination and antitermination
NW98_RS08455	COG2251	uridine kinase activity
NW98_RS08465	COG1187	pseudouridine synthase activity
NW98_RS08470	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NW98_RS08475	COG0583	DNA-binding transcription factor activity
NW98_RS08540	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
NW98_RS08575	COG0776	regulation of translation
NW98_RS08580	COG0072	phenylalanine-tRNA ligase activity
NW98_RS08580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NW98_RS08600	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NW98_RS08615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NW98_RS08620	COG0251	oxidation-reduction process
NW98_RS08625	COG2267	carboxylic ester hydrolase activity
NW98_RS08635	COG0583	DNA-binding transcription factor activity
NW98_RS08650	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS08705	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS08740	COG3251	PFAM MbtH domain protein
NW98_RS08765	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS08775	COG2207	Transcriptional regulator
NW98_RS08785	COG0835	chemotaxis
NW98_RS08810	COG0318	PFAM AMP-dependent synthetase and ligase
NW98_RS08815	COG0477	Major facilitator Superfamily
NW98_RS08835	COG1732	Glycine betaine
NW98_RS08840	COG1174	glycine betaine transport
NW98_RS08845	COG1125	glycine betaine transport
NW98_RS08850	COG1174	glycine betaine transport
NW98_RS08870	COG2235	arginine
NW98_RS08875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NW98_RS08900	COG0583	DNA-binding transcription factor activity
NW98_RS08910	COG0625	glutathione transferase activity
NW98_RS08925	COG1846	Transcriptional regulator
NW98_RS08935	COG1649	PFAM Uncharacterised BCR, COG1649
NW98_RS08965	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NW98_RS08985	COG3979	chitinase
NW98_RS09005	COG0400	carboxylic ester hydrolase activity
NW98_RS09065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NW98_RS09070	COG4774	siderophore transport
NW98_RS09075	COG3486	L-lysine 6-monooxygenase (NADPH) activity
NW98_RS09130	COG1120	ATPase activity
NW98_RS09155	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS09160	COG1070	Carbohydrate kinase
NW98_RS09165	COG1063	alcohol dehydrogenase
NW98_RS09175	COG1172	Belongs to the binding-protein-dependent transport system permease family
NW98_RS09180	COG1129	ABC transporter
NW98_RS09185	COG1879	ABC-type sugar transport system periplasmic component
NW98_RS09225	COG2375	cellular response to nickel ion
NW98_RS09225	COG1132	(ABC) transporter
NW98_RS09235	COG3121	Chaperone
NW98_RS09240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NW98_RS09250	COG1309	transcriptional regulator
NW98_RS09260	COG0765	amino acid transport
NW98_RS09265	COG4597	amino acid ABC transporter
NW98_RS09280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NW98_RS09325	COG4964	Belongs to the GSP D family
NW98_RS09350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NW98_RS09355	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NW98_RS09370	COG0477	Major facilitator Superfamily
NW98_RS09380	COG2719	SpoVR family
NW98_RS09385	COG2718	Belongs to the UPF0229 family
NW98_RS09390	COG2766	serine protein kinase
NW98_RS09405	COG0583	DNA-binding transcription factor activity
NW98_RS09410	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NW98_RS09415	COG4208	sulfate ABC transporter
NW98_RS09420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NW98_RS09425	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NW98_RS09475	COG0701	Predicted permease
NW98_RS09480	COG0667	Aldo Keto reductase
NW98_RS09510	COG1301	dicarboxylic acid transport
NW98_RS09570	COG1116	anion transmembrane transporter activity
NW98_RS09575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NW98_RS09640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NW98_RS09645	COG0765	amino acid transport
NW98_RS09655	COG0673	inositol 2-dehydrogenase activity
NW98_RS09660	COG1802	Transcriptional regulator
NW98_RS09670	COG3023	N-Acetylmuramoyl-L-alanine amidase
NW98_RS09680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NW98_RS09685	COG0557	exoribonuclease II activity
NW98_RS09705	COG0840	transmembrane signaling receptor activity
NW98_RS09735	COG0519	Catalyzes the synthesis of GMP from XMP
NW98_RS09745	COG2814	Major facilitator Superfamily
NW98_RS09755	COG0318	PFAM AMP-dependent synthetase and ligase
NW98_RS09825	COG4964	Belongs to the GSP D family
NW98_RS09865	COG1177	transmembrane transport
NW98_RS09870	COG1176	ABC-type spermidine putrescine transport system, permease component I
NW98_RS09875	COG3842	ATPase activity
NW98_RS09880	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NW98_RS09885	COG1914	H( )-stimulated, divalent metal cation uptake system
NW98_RS09900	COG3047	cAMP biosynthetic process
NW98_RS09905	COG2070	2-Nitropropane dioxygenase
NW98_RS09925	COG0488	(ABC) transporter
NW98_RS09935	COG2982	Protein involved in outer membrane biogenesis
NW98_RS09940	COG1122	ATPase activity
NW98_RS09945	COG0390	transport system, permease component
NW98_RS09965	COG0560	Phosphoserine phosphatase
NW98_RS09970	COG0626	cystathionine gamma-synthase activity
NW98_RS09980	COG0183	Belongs to the thiolase family
NW98_RS10005	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS10010	COG0183	Belongs to the thiolase family
NW98_RS10015	COG3243	poly(R)-hydroxyalkanoic acid synthase
NW98_RS10025	COG0564	pseudouridine synthase activity
NW98_RS10035	COG1199	ATP-dependent helicase activity
NW98_RS10050	COG2183	response to ionizing radiation
NW98_RS10070	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NW98_RS10090	COG0330	HflC and HflK could
NW98_RS10095	COG0330	HflC and HflK could
NW98_RS10100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NW98_RS10115	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NW98_RS10150	COG0670	Belongs to the BI1 family
NW98_RS10195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NW98_RS10210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NW98_RS10230	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NW98_RS10235	COG0789	Transcriptional regulator
NW98_RS10240	COG0477	Major facilitator Superfamily
NW98_RS10245	COG3228	Belongs to the MtfA family
NW98_RS10265	COG0534	Mate efflux family protein
NW98_RS10295	COG0542	response to heat
NW98_RS10300	COG1959	2 iron, 2 sulfur cluster binding
NW98_RS10305	COG2346	COG2346, Truncated hemoglobins
NW98_RS10310	COG0314	molybdopterin synthase activity
NW98_RS10315	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NW98_RS10350	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NW98_RS10355	COG2076	Multidrug Resistance protein
NW98_RS10360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NW98_RS10365	COG0463	Glycosyl transferase, family 2
NW98_RS10375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NW98_RS10375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NW98_RS10380	COG0726	polysaccharide deacetylase
NW98_RS10385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NW98_RS10395	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NW98_RS10400	COG0791	NLP P60 protein
NW98_RS10410	COG0306	phosphate transporter
NW98_RS10455	COG1595	DNA-templated transcription, initiation
NW98_RS10485	COG0252	asparaginase activity
NW98_RS10515	COG0438	transferase activity, transferring glycosyl groups
NW98_RS10545	COG0084	hydrolase, TatD family'
NW98_RS10550	COG1247	-acetyltransferase
NW98_RS10565	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NW98_RS10570	COG0354	folic acid binding
NW98_RS10585	COG0657	acetylesterase activity
NW98_RS10590	COG2130	NADP-dependent
NW98_RS10625	COG0183	Belongs to the thiolase family
NW98_RS10630	COG1335	isochorismatase
NW98_RS10635	COG1250	3-hydroxyacyl-CoA dehydrogenase
NW98_RS10635	COG1024	Enoyl-CoA hydratase
NW98_RS10645	COG0318	PFAM AMP-dependent synthetase and ligase
NW98_RS10670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NW98_RS10680	COG0047	phosphoribosylformylglycinamidine synthase activity
NW98_RS10680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NW98_RS10690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NW98_RS10710	COG4181	ATPase activity
NW98_RS10785	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NW98_RS10815	COG1929	Belongs to the glycerate kinase type-1 family
NW98_RS10820	COG1846	Transcriptional regulator
NW98_RS10830	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NW98_RS10925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NW98_RS10940	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NW98_RS11030	COG4266	Belongs to the allantoicase family
NW98_RS11035	COG3648	Uricase
NW98_RS11035	COG3195	allantoin biosynthetic process
NW98_RS11050	COG1953	Uracil, thiamine, allantoin
NW98_RS11070	COG1619	proteins homologs of microcin C7 resistance protein MccF
NW98_RS11165	COG0697	spore germination
NW98_RS11175	COG2867	negative regulation of translational initiation
NW98_RS11185	COG0330	HflC and HflK could
NW98_RS11235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NW98_RS11275	COG0750	zinc metalloprotease
NW98_RS11290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NW98_RS11320	COG0024	Methionine aminopeptidase
NW98_RS11330	COG1187	pseudouridine synthase activity
NW98_RS11335	COG0242	peptide deformylase activity
NW98_RS11380	COG1393	Belongs to the ArsC family
NW98_RS11390	COG2890	protein-(glutamine-N5) methyltransferase activity
NW98_RS11405	COG0386	Belongs to the glutathione peroxidase family
NW98_RS11410	COG0488	(ABC) transporter
NW98_RS11430	COG0477	Major facilitator Superfamily
NW98_RS11435	COG0351	phosphomethylpyrimidine kinase
NW98_RS11450	COG1573	uracil-dna glycosylase
NW98_RS11460	COG1214	PFAM Peptidase M22, glycoprotease
NW98_RS11470	COG0513	Belongs to the DEAD box helicase family
NW98_RS11480	COG2224	Isocitrate lyase
NW98_RS11490	COG0583	DNA-binding transcription factor activity
NW98_RS11500	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NW98_RS11555	COG1752	Esterase of the alpha-beta hydrolase superfamily
NW98_RS11560	COG0791	NLP P60 protein
NW98_RS11570	COG4172	Belongs to the ABC transporter superfamily
NW98_RS11575	COG4239	(ABC) transporter, permease
NW98_RS11580	COG4174	ABC transporter (Permease)
NW98_RS11585	COG4166	transmembrane transport
NW98_RS11610	COG0243	molybdopterin cofactor binding
NW98_RS11640	COG0024	Methionine aminopeptidase
NW98_RS11660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NW98_RS11680	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NW98_RS11695	COG3958	Transketolase
NW98_RS11700	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NW98_RS11720	COG2175	clavaminate synthase activity
NW98_RS11750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NW98_RS11755	COG0529	Catalyzes the synthesis of activated sulfate
NW98_RS11755	COG2895	sulfate adenylyltransferase (ATP) activity
NW98_RS11775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NW98_RS11780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NW98_RS11820	COG0527	aspartate kinase activity
NW98_RS11830	COG0037	tRNA processing
NW98_RS11855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NW98_RS11865	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NW98_RS11875	COG1045	serine acetyltransferase
NW98_RS11890	COG0483	inositol monophosphate 1-phosphatase activity
NW98_RS11930	COG2850	peptidyl-arginine hydroxylation
NW98_RS11945	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NW98_RS11950	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
NW98_RS11955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NW98_RS11965	COG0180	Tryptophanyl-tRNA synthetase
NW98_RS11970	COG1994	Peptidase M50
NW98_RS11975	COG0009	L-threonylcarbamoyladenylate synthase
NW98_RS11980	COG0613	PHP domain protein
NW98_RS11990	COG0596	Alpha beta hydrolase
NW98_RS12000	COG2833	Protein of unknown function (DUF455)
NW98_RS12010	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NW98_RS12020	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NW98_RS12050	COG0658	competence protein
NW98_RS12050	COG2333	competence protein COMEC
NW98_RS12055	COG0084	hydrolase, TatD family'
NW98_RS12060	COG1136	(ABC) transporter
NW98_RS12080	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NW98_RS12105	COG2975	iron-sulfur cluster assembly
NW98_RS12125	COG0316	Belongs to the HesB IscA family
NW98_RS12130	COG0822	iron-sulfur transferase activity
NW98_RS12135	COG1104	cysteine desulfurase activity
NW98_RS12145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NW98_RS12170	COG1414	Transcriptional regulator
NW98_RS12200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NW98_RS12210	COG0508	dehydrogenase complex catalyzes the overall conversion of
NW98_RS12215	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NW98_RS12225	COG4566	intracellular signal transduction
NW98_RS12245	COG0339	signal peptide processing
NW98_RS12250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NW98_RS12270	COG2223	nitrite transmembrane transporter activity
NW98_RS12275	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NW98_RS12280	COG1140	nitrate reductase beta subunit
NW98_RS12285	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NW98_RS12290	COG2181	nitrate reductase activity
NW98_RS12295	COG4585	Histidine kinase
NW98_RS12300	COG2197	response regulator
NW98_RS12325	COG0174	glutamine synthetase
NW98_RS12340	COG1058	Belongs to the CinA family
NW98_RS12340	COG1546	Belongs to the CinA family
NW98_RS12365	COG1643	Atp-dependent helicase
NW98_RS12370	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NW98_RS12370	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NW98_RS12380	COG0477	Major facilitator Superfamily
NW98_RS12395	COG1960	acyl-CoA dehydrogenase activity
NW98_RS12400	COG0583	DNA-binding transcription factor activity
NW98_RS12480	COG1881	PFAM PEBP family protein
NW98_RS12485	COG2814	Major facilitator Superfamily
NW98_RS12505	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NW98_RS12535	COG1116	anion transmembrane transporter activity
NW98_RS12540	COG1176	ABC-type spermidine putrescine transport system, permease component I
NW98_RS12590	COG4215	(ABC) transporter
NW98_RS12610	COG0347	Belongs to the P(II) protein family
NW98_RS12640	COG2827	Endonuclease containing a URI domain
NW98_RS12645	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NW98_RS12660	COG2271	Major facilitator Superfamily
NW98_RS12700	COG2226	methyltransferase
NW98_RS12740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NW98_RS12765	COG0489	protein tyrosine kinase activity
NW98_RS12775	COG3047	cAMP biosynthetic process
NW98_RS12775	COG2885	chlorophyll binding
NW98_RS12805	COG2911	Protein conserved in bacteria
NW98_RS12810	COG0729	surface antigen
NW98_RS12820	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NW98_RS12840	COG0489	protein tyrosine kinase activity
NW98_RS12845	COG2259	Doxx family
NW98_RS12850	COG1492	cobalamin metabolic process
NW98_RS12870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NW98_RS12890	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NW98_RS12895	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NW98_RS12900	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NW98_RS12910	COG4206	TonB-dependent receptor
NW98_RS12965	COG4654	Cytochrome c, class I
NW98_RS12985	COG0795	lipopolysaccharide-transporting ATPase activity
NW98_RS13000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NW98_RS13000	COG1648	precorrin-2 dehydrogenase activity
NW98_RS13005	COG2895	sulfate adenylyltransferase (ATP) activity
NW98_RS13015	COG0175	sulfate reduction
NW98_RS13030	COG0583	DNA-binding transcription factor activity
NW98_RS13060	COG0174	glutamine synthetase
NW98_RS13065	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NW98_RS13100	COG0402	S-adenosylhomocysteine deaminase activity
NW98_RS13115	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NW98_RS13165	COG0529	Catalyzes the synthesis of activated sulfate
NW98_RS13170	COG0415	Belongs to the DNA photolyase family
NW98_RS13190	COG2151	metal-sulfur cluster biosynthetic enzyme
NW98_RS13230	COG3154	lipid carrier protein
NW98_RS13235	COG0826	peptidase U32
NW98_RS13240	COG0826	peptidase U32
NW98_RS13260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NW98_RS13265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NW98_RS13270	COG0840	transmembrane signaling receptor activity
NW98_RS13295	COG0396	ATPase activity
NW98_RS13305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NW98_RS13310	COG0822	iron-sulfur transferase activity
NW98_RS13315	COG2151	metal-sulfur cluster biosynthetic enzyme
NW98_RS13330	COG1959	2 iron, 2 sulfur cluster binding
NW98_RS13360	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NW98_RS13370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NW98_RS13380	COG2988	succinylglutamate desuccinylase activity
NW98_RS13405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NW98_RS13445	COG3511	phospholipase C
NW98_RS13455	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NW98_RS13465	COG0596	Alpha beta hydrolase
NW98_RS13475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NW98_RS13490	COG3394	polysaccharide catabolic process
NW98_RS13520	COG0683	leucine binding
NW98_RS13525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NW98_RS13540	COG0438	transferase activity, transferring glycosyl groups
NW98_RS13545	COG1132	(ABC) transporter
NW98_RS13550	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NW98_RS13565	COG1999	signal sequence binding
NW98_RS13580	COG2153	protein acetylation
NW98_RS13595	COG0583	DNA-binding transcription factor activity
NW98_RS13600	COG1956	GAF domain-containing protein
NW98_RS13620	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NW98_RS13640	COG2204	response regulator
NW98_RS13655	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NW98_RS13660	COG1381	Involved in DNA repair and RecF pathway recombination
NW98_RS13665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NW98_RS13670	COG0571	ribonuclease III activity
NW98_RS13675	COG0681	Belongs to the peptidase S26 family
NW98_RS13690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NW98_RS13695	COG3026	antisigma factor binding
NW98_RS13715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NW98_RS13750	COG1399	metal-binding, possibly nucleic acid-binding protein
NW98_RS13790	COG1530	ribonuclease E activity
NW98_RS13795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NW98_RS13805	COG0303	'Molybdopterin
NW98_RS13820	COG1322	Protein conserved in bacteria
NW98_RS13840	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NW98_RS13850	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NW98_RS13865	COG3045	CreA protein
NW98_RS13885	COG2501	S4 domain
NW98_RS13890	COG0534	Mate efflux family protein
NW98_RS13910	COG0114	fumarate hydratase activity
NW98_RS13930	COG0640	Transcriptional regulator
NW98_RS14000	COG4772	TonB-dependent receptor
NW98_RS14070	COG0583	DNA-binding transcription factor activity
NW98_RS14080	COG0308	aminopeptidase N
NW98_RS14095	COG2119	membrane
NW98_RS14105	COG0402	S-adenosylhomocysteine deaminase activity
NW98_RS14110	COG2252	PERMEase
NW98_RS14115	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NW98_RS14135	COG0154	amidase activity
NW98_RS14145	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NW98_RS14190	COG3383	formate dehydrogenase (NAD+) activity
NW98_RS14205	COG1910	domain protein
NW98_RS14215	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NW98_RS14240	COG0546	phosphoglycolate phosphatase activity
NW98_RS14270	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NW98_RS14275	COG0077	Prephenate dehydratase
NW98_RS14275	COG1605	Chorismate mutase
NW98_RS14280	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NW98_RS14310	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NW98_RS14320	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NW98_RS14345	COG2951	lytic endotransglycosylase activity
NW98_RS14350	COG0123	including yeast histone deacetylase and acetoin utilization protein
NW98_RS14360	COG2267	carboxylic ester hydrolase activity
NW98_RS14370	COG2011	ABC-type metal ion transport system permease component
NW98_RS14470	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NW98_RS14485	COG0501	Belongs to the peptidase M48B family
NW98_RS14495	COG0521	Mo-molybdopterin cofactor biosynthetic process
NW98_RS14500	COG3028	Belongs to the UPF0307 family
NW98_RS14510	COG0312	modulator of DNA gyrase
NW98_RS14520	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NW98_RS14525	COG2204	response regulator
NW98_RS14550	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NW98_RS14575	COG0728	peptidoglycan biosynthetic process
NW98_RS14595	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NW98_RS14600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NW98_RS14610	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NW98_RS14615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NW98_RS14620	COG0318	PFAM AMP-dependent synthetase and ligase
NW98_RS14625	COG4974	Belongs to the 'phage' integrase family
NW98_RS14635	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NW98_RS14640	COG0802	atpase or kinase
NW98_RS14645	COG0860	N-Acetylmuramoyl-L-alanine amidase
NW98_RS14660	COG1741	Belongs to the pirin family
NW98_RS14675	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NW98_RS14685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NW98_RS14700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NW98_RS14710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NW98_RS14715	COG1522	sequence-specific DNA binding
NW98_RS14735	COG2271	Major facilitator Superfamily
NW98_RS14745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NW98_RS14750	COG1012	belongs to the aldehyde dehydrogenase family
NW98_RS14760	COG0583	DNA-binding transcription factor activity
NW98_RS14765	COG0246	Mannitol dehydrogenase
NW98_RS14770	COG1070	Carbohydrate kinase
NW98_RS14775	COG2390	Transcriptional regulator
NW98_RS14790	COG0583	DNA-binding transcription factor activity
NW98_RS14805	COG3842	ATPase activity
NW98_RS14810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NW98_RS14820	COG1175	transmembrane transport
NW98_RS14835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NW98_RS14845	COG0735	belongs to the Fur family
NW98_RS14855	COG1121	(ABC) transporter
NW98_RS14860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NW98_RS14865	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NW98_RS14885	COG2233	PERMEase
NW98_RS14915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NW98_RS14920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NW98_RS14950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NW98_RS14995	COG0009	L-threonylcarbamoyladenylate synthase
NW98_RS15000	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NW98_RS15005	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NW98_RS15010	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NW98_RS15020	COG0469	pyruvate kinase activity
NW98_RS15030	COG0126	phosphoglycerate kinase activity
NW98_RS15055	COG0859	PFAM glycosyl transferase family 9
NW98_RS15065	COG0429	hydrolase of the alpha beta-hydrolase fold
NW98_RS15075	COG4783	chaperone-mediated protein folding
NW98_RS15115	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NW98_RS15120	COG2137	regulation of response to DNA damage stimulus
NW98_RS15135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NW98_RS15140	COG0861	Integral membrane protein TerC family
NW98_RS15145	COG4969	Belongs to the N-Me-Phe pilin family
NW98_RS15150	COG3307	-O-antigen
NW98_RS15190	COG0840	transmembrane signaling receptor activity
NW98_RS15235	COG4948	Mandelate Racemase Muconate Lactonizing
NW98_RS15265	COG0513	Belongs to the DEAD box helicase family
NW98_RS15310	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NW98_RS15315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NW98_RS15330	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NW98_RS15335	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NW98_RS15340	COG0367	asparagine synthase
NW98_RS15355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NW98_RS15365	COG1396	sequence-specific DNA binding
NW98_RS15370	COG2814	Major facilitator Superfamily
NW98_RS15375	COG0583	DNA-binding transcription factor activity
NW98_RS15390	COG1702	phosphate starvation-inducible protein PhoH
NW98_RS15405	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
NW98_RS15415	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NW98_RS15420	COG0752	glycyl-tRNA synthetase alpha subunit
NW98_RS15425	COG0751	glycine-tRNA ligase activity
NW98_RS15430	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NW98_RS15435	COG0204	Acyl-transferase
NW98_RS15465	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NW98_RS15470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NW98_RS15485	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NW98_RS15495	COG5265	(ABC) transporter
NW98_RS15515	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NW98_RS15520	COG1024	Enoyl-CoA hydratase
NW98_RS15525	COG0183	Belongs to the thiolase family
NW98_RS15530	COG1250	3-hydroxyacyl-CoA dehydrogenase
NW98_RS15530	COG1024	Enoyl-CoA hydratase
NW98_RS15535	COG1960	acyl-CoA dehydrogenase activity
NW98_RS15550	COG0494	nUDIX hydrolase
NW98_RS15620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NW98_RS15630	COG0251	oxidation-reduction process
NW98_RS15640	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NW98_RS15665	COG0477	Major facilitator Superfamily
NW98_RS15695	COG0708	Exodeoxyribonuclease III
NW98_RS15700	COG2326	polyphosphate kinase activity
NW98_RS15720	COG1077	Cell shape determining protein MreB Mrl
NW98_RS15735	COG0768	penicillin binding
NW98_RS15740	COG0772	Belongs to the SEDS family
NW98_RS15765	COG0720	synthase
NW98_RS15770	COG0602	queuosine metabolic process
NW98_RS15790	COG2204	response regulator
NW98_RS15795	COG5000	phosphorelay sensor kinase activity
NW98_RS15805	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NW98_RS15805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NW98_RS15825	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NW98_RS15830	COG0242	peptide deformylase activity
NW98_RS15835	COG0758	DNA mediated transformation
NW98_RS15850	COG0583	DNA-binding transcription factor activity
NW98_RS15855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NW98_RS15910	COG4695	Portal protein
NW98_RS15920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NW98_RS15935	COG0583	DNA-binding transcription factor activity
NW98_RS15965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NW98_RS15980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NW98_RS15980	COG2169	Transcriptional regulator
NW98_RS16080	COG1396	sequence-specific DNA binding
NW98_RS16105	COG1309	transcriptional regulator
NW98_RS16130	COG0473	3-isopropylmalate dehydrogenase activity
NW98_RS16135	COG0583	DNA-binding transcription factor activity
NW98_RS16155	COG0625	glutathione transferase activity
NW98_RS16180	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS16190	COG0671	phosphoesterase, PA-phosphatase related
NW98_RS16250	COG1032	radical SAM domain protein
NW98_RS16265	COG0583	DNA-binding transcription factor activity
NW98_RS16270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NW98_RS16275	COG0589	response to stress
NW98_RS16315	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NW98_RS16345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NW98_RS16370	COG4774	siderophore transport
NW98_RS16375	COG1120	ATPase activity
NW98_RS16385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NW98_RS16430	COG0730	response to heat
NW98_RS16445	COG0584	glycerophosphoryl diester phosphodiesterase
NW98_RS16450	COG1280	lysine exporter protein (LysE YggA)
NW98_RS16510	COG0604	alcohol dehydrogenase
NW98_RS16515	COG1733	regulation of RNA biosynthetic process
NW98_RS16530	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NW98_RS16545	COG1773	rubredoxin
NW98_RS16565	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NW98_RS16640	COG1215	transferase activity, transferring glycosyl groups
NW98_RS16655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NW98_RS16700	COG0456	acetyltransferase
NW98_RS16705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NW98_RS16710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NW98_RS16710	COG0543	2 iron, 2 sulfur cluster binding
NW98_RS16725	COG1187	pseudouridine synthase activity
NW98_RS16735	COG0583	DNA-binding transcription factor activity
NW98_RS16745	COG2267	carboxylic ester hydrolase activity
NW98_RS16750	COG2258	MOSC domain
NW98_RS16755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NW98_RS16765	COG1396	sequence-specific DNA binding
NW98_RS16780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NW98_RS16785	COG0697	spore germination
NW98_RS16795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NW98_RS16820	COG4106	trans-aconitate 2-methyltransferase activity
NW98_RS16835	COG2764	glyoxalase bleomycin resistance protein dioxygenase
NW98_RS16850	COG3135	benzoate transporter
NW98_RS16900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NW98_RS16905	COG2878	Part of a membrane complex involved in electron transport
NW98_RS16910	COG1309	transcriptional regulator
NW98_RS16920	COG3387	PFAM Glycoside hydrolase 15-related
NW98_RS16930	COG2706	6-phosphogluconolactonase activity
NW98_RS16940	COG1674	ftsk spoiiie
NW98_RS16975	COG0513	Belongs to the DEAD box helicase family
NW98_RS16985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NW98_RS17025	COG0438	transferase activity, transferring glycosyl groups
NW98_RS17030	COG0859	PFAM glycosyl transferase family 9
NW98_RS17070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NW98_RS17080	COG1595	DNA-templated transcription, initiation
NW98_RS17135	COG2233	PERMEase
NW98_RS17160	COG0799	negative regulation of ribosome biogenesis
NW98_RS17175	COG0151	Belongs to the GarS family
NW98_RS17195	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS17225	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NW98_RS17230	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NW98_RS17250	COG0745	RESPONSE REGULATOR receiver
NW98_RS17285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NW98_RS17295	COG0154	amidase activity
NW98_RS17325	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS17345	COG0438	transferase activity, transferring glycosyl groups
NW98_RS17380	COG0028	Belongs to the TPP enzyme family
NW98_RS17400	COG1183	phosphatidylcholine synthase activity
NW98_RS17410	COG0659	secondary active sulfate transmembrane transporter activity
NW98_RS17415	COG0288	reversible hydration of carbon dioxide
NW98_RS17430	COG0683	leucine binding
NW98_RS17450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NW98_RS17450	COG3321	synthase
NW98_RS17450	COG0604	alcohol dehydrogenase
NW98_RS17450	COG4221	oxidoreductase activity
NW98_RS17455	COG0149	triose-phosphate isomerase activity
NW98_RS17490	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NW98_RS17500	COG1034	ATP synthesis coupled electron transport
NW98_RS17535	COG1007	ATP synthesis coupled electron transport
NW98_RS17555	COG1960	acyl-CoA dehydrogenase activity
NW98_RS17560	COG1960	acyl-CoA dehydrogenase activity
NW98_RS17565	COG1012	belongs to the aldehyde dehydrogenase family
NW98_RS17565	COG2030	dehydratase
NW98_RS17585	COG1960	acyl-CoA dehydrogenase activity
NW98_RS17595	COG0588	phosphoglycerate mutase activity
NW98_RS17600	COG1024	Enoyl-CoA hydratase
NW98_RS17610	COG0436	Aminotransferase
NW98_RS17625	COG2866	Carboxypeptidase
NW98_RS17720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NW98_RS17725	COG4221	oxidoreductase activity
NW98_RS17730	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS17750	COG0747	negative chemotaxis
NW98_RS17755	COG0488	(ABC) transporter
NW98_RS17775	COG0288	reversible hydration of carbon dioxide
NW98_RS17780	COG0183	Belongs to the thiolase family
NW98_RS17790	COG3012	SEC-C Motif Domain Protein
NW98_RS17840	COG1785	Belongs to the alkaline phosphatase family
NW98_RS17860	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS17885	COG0840	transmembrane signaling receptor activity
NW98_RS17890	COG1609	Transcriptional regulator
NW98_RS17950	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NW98_RS17965	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NW98_RS17970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NW98_RS17990	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NW98_RS17995	COG1704	LemA family
NW98_RS18055	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NW98_RS18065	COG0312	modulator of DNA gyrase
NW98_RS18070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NW98_RS18075	COG3164	Protein of unknown function
NW98_RS18080	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NW98_RS18085	COG0497	DNA recombination
NW98_RS18130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NW98_RS18140	COG1428	Deoxynucleoside kinase
NW98_RS18145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NW98_RS18150	COG0617	tRNA 3'-terminal CCA addition
NW98_RS18160	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NW98_RS18190	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NW98_RS18195	COG0586	Pfam SNARE associated Golgi protein
NW98_RS18295	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NW98_RS18310	COG1368	sulfuric ester hydrolase activity
NW98_RS18315	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS18315	COG0604	alcohol dehydrogenase
NW98_RS18315	COG3321	synthase
NW98_RS18320	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NW98_RS18325	COG0156	8-amino-7-oxononanoate synthase activity
NW98_RS18365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NW98_RS18405	COG0656	L-ascorbic acid biosynthetic process
NW98_RS18410	COG2188	Transcriptional regulator
NW98_RS18430	COG2814	Major facilitator Superfamily
NW98_RS18485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NW98_RS18490	COG1570	exodeoxyribonuclease VII activity
NW98_RS18500	COG1663	tetraacyldisaccharide 4'-kinase activity
NW98_RS18530	COG1278	Cold shock
NW98_RS18540	COG0542	response to heat
NW98_RS18580	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NW98_RS18585	COG0196	riboflavin kinase activity
NW98_RS18590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NW98_RS18595	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NW98_RS18595	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NW98_RS18600	COG3264	Mechanosensitive ion channel
NW98_RS18600	COG1511	domain protein
NW98_RS18625	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NW98_RS18645	COG1047	Peptidyl-prolyl cis-trans
NW98_RS18650	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NW98_RS18705	COG1773	rubredoxin
NW98_RS18720	COG0488	(ABC) transporter
NW98_RS18750	COG0583	DNA-binding transcription factor activity
NW98_RS18760	COG0583	DNA-binding transcription factor activity
NW98_RS18770	COG0477	Major facilitator Superfamily
NW98_RS18825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NW98_RS18855	COG0859	PFAM glycosyl transferase family 9
NW98_RS18910	COG1129	ABC transporter
NW98_RS18920	COG0559	Belongs to the binding-protein-dependent transport system permease family
NW98_RS18935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NW98_RS18945	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NW98_RS18955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NW98_RS18980	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NW98_RS18990	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NW98_RS18995	COG2226	methyltransferase
NW98_RS19030	COG0762	integral membrane protein
NW98_RS19065	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NW98_RS19085	COG0436	Aminotransferase
NW98_RS19115	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NW98_RS19115	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NW98_RS19140	COG2814	Major facilitator Superfamily
NW98_RS19155	COG1126	abc transporter atp-binding protein
NW98_RS19160	COG0765	amino acid transport
NW98_RS19165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NW98_RS19180	COG0363	glucosamine-6-phosphate deaminase activity
NW98_RS19185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NW98_RS19195	COG1175	transmembrane transport
NW98_RS19200	COG0395	ABC-type sugar transport system, permease component
NW98_RS19205	COG3842	ATPase activity
NW98_RS19210	COG2860	membrane
NW98_RS19215	COG1193	negative regulation of DNA recombination
NW98_RS19220	COG0492	ferredoxin-NADP+ reductase activity
NW98_RS19225	COG1674	ftsk spoiiie
NW98_RS19230	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NW98_RS19240	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NW98_RS19285	COG2894	cell division
NW98_RS19305	COG0859	PFAM glycosyl transferase family 9
NW98_RS19315	COG0477	Major facilitator Superfamily
NW98_RS19350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NW98_RS19355	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NW98_RS19365	COG1561	YicC-like family, N-terminal region
NW98_RS19380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NW98_RS19435	COG2885	chlorophyll binding
NW98_RS19440	COG0823	Involved in the tonB-independent uptake of proteins
NW98_RS19460	COG0824	Thioesterase
NW98_RS19465	COG4221	oxidoreductase activity
NW98_RS19525	COG0450	alkyl hydroperoxide reductase
NW98_RS19535	COG1960	acyl-CoA dehydrogenase activity
NW98_RS19570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NW98_RS19580	COG2814	Major facilitator Superfamily
NW98_RS19605	COG2814	Major facilitator Superfamily
NW98_RS19610	COG0778	Nitroreductase
NW98_RS19615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NW98_RS19620	COG0583	DNA-binding transcription factor activity
NW98_RS19655	COG1045	serine acetyltransferase
NW98_RS19660	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS19665	COG0302	gtp cyclohydrolase
NW98_RS19685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NW98_RS19690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NW98_RS19695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NW98_RS19700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NW98_RS19775	COG1595	DNA-templated transcription, initiation
NW98_RS19780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NW98_RS19815	COG2916	Histone family protein nucleoid-structuring protein H-NS
NW98_RS19830	COG0477	Major facilitator Superfamily
NW98_RS20000	COG0596	Alpha beta hydrolase
NW98_RS20040	COG0625	glutathione transferase activity
NW98_RS20060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NW98_RS20065	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NW98_RS20095	COG0295	cytidine deaminase activity
NW98_RS20105	COG2823	Periplasmic or secreted lipoprotein
NW98_RS20130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NW98_RS20135	COG0280	phosphate acetyltransferase
NW98_RS20140	COG3243	poly(R)-hydroxyalkanoic acid synthase
NW98_RS20155	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NW98_RS20170	COG0356	it plays a direct role in the translocation of protons across the membrane
NW98_RS20180	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NW98_RS20180	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NW98_RS20215	COG0840	transmembrane signaling receptor activity
NW98_RS20225	COG4191	Histidine kinase
NW98_RS20225	COG0784	Response regulator, receiver
NW98_RS20230	COG0842	Transport permease protein
NW98_RS20235	COG1129	ABC transporter
NW98_RS20235	COG0842	Transport permease protein
NW98_RS20260	COG0589	response to stress
NW98_RS20275	COG1136	(ABC) transporter
NW98_RS20300	COG0840	transmembrane signaling receptor activity
NW98_RS20340	COG1611	Belongs to the LOG family
NW98_RS20375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NW98_RS20385	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS20395	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NW98_RS20440	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS20470	COG3537	Alpha-1,2-mannosidase
NW98_RS20505	COG0367	asparagine synthase
NW98_RS20555	COG2885	chlorophyll binding
NW98_RS20675	COG0583	DNA-binding transcription factor activity
NW98_RS20730	COG1984	allophanate hydrolase subunit 2
NW98_RS20745	COG0511	ligase activity, forming carbon-carbon bonds
NW98_RS20750	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NW98_RS20815	COG0840	transmembrane signaling receptor activity
NW98_RS20875	COG0535	radical SAM domain protein
NW98_RS20885	COG0840	transmembrane signaling receptor activity
NW98_RS20910	COG1285	pathogenesis
NW98_RS20995	COG0346	lactoylglutathione lyase activity
NW98_RS21005	COG1562	ergosterol biosynthetic process
NW98_RS21030	COG1294	oxidase, subunit
NW98_RS21035	COG1271	oxidase subunit
NW98_RS21045	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
NW98_RS21060	COG2860	membrane
NW98_RS21065	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NW98_RS21075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NW98_RS21085	COG4558	Periplasmic binding protein
NW98_RS21090	COG3720	iron ion transport
NW98_RS21120	COG3842	ATPase activity
NW98_RS21125	COG1840	ABC-type Fe3 transport system, periplasmic component
NW98_RS21140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS21150	COG0698	ribose 5-phosphate isomerase
NW98_RS21155	COG1129	ABC transporter
NW98_RS21160	COG1172	Belongs to the binding-protein-dependent transport system permease family
NW98_RS21165	COG1879	ABC-type sugar transport system periplasmic component
NW98_RS21170	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS21175	COG1063	alcohol dehydrogenase
NW98_RS21180	COG2376	Dihydroxyacetone kinase
NW98_RS21235	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NW98_RS21270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NW98_RS21290	COG3634	alkyl hydroperoxide reductase activity
NW98_RS21310	COG0778	Nitroreductase
NW98_RS21320	COG2308	Evidence 4 Homologs of previously reported genes of
NW98_RS21350	COG1305	Transglutaminase-like
NW98_RS21355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NW98_RS21375	COG4977	sequence-specific DNA binding
NW98_RS21385	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NW98_RS21440	COG0531	amino acid
NW98_RS21445	COG3384	dioxygenase
NW98_RS21455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NW98_RS21460	COG2890	protein-(glutamine-N5) methyltransferase activity
NW98_RS21490	COG0006	proline dipeptidase activity
NW98_RS21495	COG1335	isochorismatase
NW98_RS21505	COG0488	(ABC) transporter
NW98_RS21520	COG0584	glycerophosphoryl diester phosphodiesterase
NW98_RS21555	COG0012	GTP binding
NW98_RS21585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NW98_RS21590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NW98_RS21605	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NW98_RS21625	COG0512	Glutamine amidotransferase of anthranilate synthase
NW98_RS21640	COG0546	phosphoglycolate phosphatase activity
NW98_RS21645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NW98_RS21655	COG2967	ApaG domain
NW98_RS21665	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NW98_RS21680	COG1024	Enoyl-CoA hydratase
NW98_RS21685	COG0183	Belongs to the thiolase family
NW98_RS21695	COG1024	Enoyl-CoA hydratase
NW98_RS21795	COG0798	PFAM Bile acid sodium symporter
NW98_RS21810	COG0640	Transcriptional regulator
NW98_RS21850	COG4175	Glycine betaine
NW98_RS21900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NW98_RS21905	COG3622	Belongs to the hyi family
NW98_RS21910	COG2271	Major facilitator Superfamily
NW98_RS21915	COG0235	Class ii aldolase
NW98_RS21920	COG3395	kinase activity
NW98_RS21925	COG2084	Dehydrogenase
NW98_RS21930	COG2186	Transcriptional regulator
NW98_RS21970	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS22015	COG0583	DNA-binding transcription factor activity
NW98_RS22040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS22055	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NW98_RS22060	COG2508	Transcriptional regulator
NW98_RS22100	COG0038	chloride channel
NW98_RS22115	COG1858	cytochrome C peroxidase
NW98_RS22120	COG3511	phospholipase C
NW98_RS22145	COG2197	response regulator
NW98_RS22225	COG1024	Enoyl-CoA hydratase
NW98_RS22230	COG1012	belongs to the aldehyde dehydrogenase family
NW98_RS22240	COG2814	Major facilitator Superfamily
NW98_RS22255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS22280	COG1129	ABC transporter
NW98_RS22285	COG1172	Belongs to the binding-protein-dependent transport system permease family
NW98_RS22295	COG2721	sulfolactate sulfo-lyase activity
NW98_RS22310	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS22320	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS22380	COG5295	Hep Hag repeat protein
NW98_RS22380	COG5295	Hep Hag repeat protein
NW98_RS22390	COG2916	Histone family protein nucleoid-structuring protein H-NS
NW98_RS22445	COG1272	protein, Hemolysin III
NW98_RS22465	COG1522	sequence-specific DNA binding
NW98_RS22480	COG1448	Aminotransferase
NW98_RS22535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NW98_RS22535	COG4191	Histidine kinase
NW98_RS22540	COG2201	protein-glutamate methylesterase activity
NW98_RS22555	COG2373	Large extracellular alpha-helical protein
NW98_RS22590	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NW98_RS22605	COG2175	clavaminate synthase activity
NW98_RS22610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NW98_RS22630	COG3291	Pkd domain containing protein
NW98_RS22645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NW98_RS22710	COG0589	response to stress
NW98_RS22745	COG4221	oxidoreductase activity
NW98_RS22760	COG1113	amino acid transport
NW98_RS22775	COG2916	Histone family protein nucleoid-structuring protein H-NS
NW98_RS22830	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NW98_RS22835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NW98_RS22840	COG2271	Major facilitator Superfamily
NW98_RS22865	COG1176	ABC-type spermidine putrescine transport system, permease component I
NW98_RS22880	COG1012	belongs to the aldehyde dehydrogenase family
NW98_RS22955	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NW98_RS22960	COG0667	Aldo Keto reductase
NW98_RS22965	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS22980	COG0556	nucleotide-excision repair
NW98_RS22990	COG4633	Protein conserved in bacteria
NW98_RS22995	COG0672	)-iron permease
NW98_RS23005	COG3193	protein, possibly involved in utilization of glycolate and propanediol
NW98_RS23055	COG0583	DNA-binding transcription factor activity
NW98_RS23100	COG1012	belongs to the aldehyde dehydrogenase family
NW98_RS23105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NW98_RS23110	COG0531	amino acid
NW98_RS23125	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS23145	COG1902	pentaerythritol trinitrate reductase activity
NW98_RS23160	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS23165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NW98_RS23180	COG0516	GMP reductase activity
NW98_RS23180	COG0517	IMP dehydrogenase activity
NW98_RS23185	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NW98_RS23210	COG2197	response regulator
NW98_RS23215	COG1285	pathogenesis
NW98_RS23225	COG1408	metallophosphoesterase
NW98_RS23240	COG1414	Transcriptional regulator
NW98_RS23245	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS23255	COG2146	nitrite reductase [NAD(P)H] activity
NW98_RS23285	COG1414	Transcriptional regulator
NW98_RS23290	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS23295	COG0028	Belongs to the TPP enzyme family
NW98_RS23305	COG1012	belongs to the aldehyde dehydrogenase family
NW98_RS23320	COG0477	Major facilitator Superfamily
NW98_RS23350	COG0154	amidase activity
NW98_RS23360	COG1522	sequence-specific DNA binding
NW98_RS23410	COG0492	ferredoxin-NADP+ reductase activity
NW98_RS23435	COG0596	Alpha beta hydrolase
NW98_RS23465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NW98_RS23490	COG0840	transmembrane signaling receptor activity
NW98_RS23495	COG0840	transmembrane signaling receptor activity
NW98_RS23525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NW98_RS23530	COG0596	Alpha beta hydrolase
NW98_RS23575	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS23615	COG0583	DNA-binding transcription factor activity
NW98_RS23640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NW98_RS23645	COG0601	transmembrane transport
NW98_RS23655	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NW98_RS23690	COG3209	COG3209 Rhs family protein
NW98_RS23735	COG2140	Oxalate decarboxylase
NW98_RS23740	COG1914	H( )-stimulated, divalent metal cation uptake system
NW98_RS23750	COG4682	membrane
NW98_RS23755	COG3781	membrane
NW98_RS23760	COG0243	molybdopterin cofactor binding
NW98_RS23765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NW98_RS23790	COG1404	Belongs to the peptidase S8 family
NW98_RS23815	COG2259	Doxx family
NW98_RS23840	COG4160	amino acid transport
NW98_RS23845	COG4598	ABC transporter
NW98_RS23850	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NW98_RS23915	COG3275	phosphorelay sensor kinase activity
NW98_RS23925	COG3279	Response regulator of the LytR AlgR family
NW98_RS23950	COG0500	methyltransferase
NW98_RS23955	COG2207	Transcriptional regulator
NW98_RS23975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NW98_RS23980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NW98_RS23985	COG1024	Enoyl-CoA hydratase
NW98_RS23990	COG1024	Enoyl-CoA hydratase
NW98_RS24010	COG3425	synthase
NW98_RS24035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NW98_RS24035	COG2070	2-Nitropropane dioxygenase
NW98_RS24040	COG0475	glutathione-regulated potassium exporter activity
NW98_RS24040	COG0569	domain protein
NW98_RS24065	COG4221	oxidoreductase activity
NW98_RS24065	COG3321	synthase
NW98_RS24065	COG0300	oxidoreductase activity
NW98_RS24065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NW98_RS24100	COG0583	DNA-binding transcription factor activity
NW98_RS24110	COG0387	Pfam Sodium calcium exchanger
NW98_RS24135	COG0179	Fumarylacetoacetate (FAA) hydrolase
NW98_RS24165	COG2353	YceI-like domain
NW98_RS24185	COG1595	DNA-templated transcription, initiation
NW98_RS24195	COG4774	siderophore transport
NW98_RS24200	COG1172	Belongs to the binding-protein-dependent transport system permease family
NW98_RS24205	COG1172	Belongs to the binding-protein-dependent transport system permease family
NW98_RS24210	COG1129	ABC transporter
NW98_RS24245	COG1960	acyl-CoA dehydrogenase activity
NW98_RS24255	COG2271	Major facilitator Superfamily
NW98_RS24385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NW98_RS24390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NW98_RS24405	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NW98_RS24420	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NW98_RS24450	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS24455	COG4651	solute:proton antiporter activity
NW98_RS24455	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NW98_RS24510	COG1349	DNA-binding transcription factor activity
NW98_RS24515	COG2223	nitrite transmembrane transporter activity
NW98_RS24560	COG1063	alcohol dehydrogenase
NW98_RS24565	COG3842	ATPase activity
NW98_RS24575	COG1070	Carbohydrate kinase
NW98_RS24600	COG0243	molybdopterin cofactor binding
NW98_RS24605	COG2146	nitrite reductase [NAD(P)H] activity
NW98_RS24610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NW98_RS24635	COG3707	response regulator
NW98_RS24640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NW98_RS24640	COG1116	anion transmembrane transporter activity
NW98_RS24650	COG0302	gtp cyclohydrolase
NW98_RS24690	COG0477	Major facilitator Superfamily
NW98_RS24745	COG2130	NADP-dependent
NW98_RS24750	COG1979	alcohol dehydrogenase
NW98_RS24815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NW98_RS24830	COG3321	synthase
NW98_RS24830	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NW98_RS24830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NW98_RS24830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NW98_RS24855	COG0531	amino acid
NW98_RS24875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NW98_RS24880	COG4122	O-methyltransferase activity
NW98_RS24890	COG3706	GGDEF domain
NW98_RS24890	COG4251	negative regulation of phosphorylation
NW98_RS24890	COG2203	Gaf domain
NW98_RS24890	COG5001	Diguanylate cyclase
NW98_RS24905	COG0583	DNA-binding transcription factor activity
NW98_RS24910	COG3485	protocatechuate 3,4-dioxygenase
NW98_RS24915	COG3485	protocatechuate 3,4-dioxygenase
NW98_RS24935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NW98_RS24940	COG0601	transmembrane transport
NW98_RS24945	COG0747	negative chemotaxis
NW98_RS24955	COG4172	Belongs to the ABC transporter superfamily
NW98_RS24960	COG1446	asparaginase
NW98_RS24970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NW98_RS25015	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NW98_RS25025	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NW98_RS25035	COG0277	FAD linked oxidase domain protein
NW98_RS25090	COG2188	Transcriptional regulator
NW98_RS25095	COG2814	Major facilitator Superfamily
NW98_RS25110	COG1858	cytochrome C peroxidase
NW98_RS25115	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NW98_RS25140	COG0456	acetyltransferase
NW98_RS25150	COG2391	methyltransferase activity
NW98_RS25155	COG0640	Transcriptional regulator
NW98_RS25165	COG3038	cytochrome b561
NW98_RS25175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NW98_RS25180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NW98_RS25190	COG1045	serine acetyltransferase
NW98_RS25205	COG1505	serine-type exopeptidase activity
NW98_RS25225	COG1566	PFAM secretion protein HlyD family protein
NW98_RS25250	COG2814	Major facilitator Superfamily
NW98_RS25285	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NW98_RS25310	COG0477	Major facilitator Superfamily
NW98_RS25320	COG0784	Response regulator, receiver
NW98_RS25325	COG4251	negative regulation of phosphorylation
NW98_RS25340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NW98_RS25370	COG1278	Cold shock
NW98_RS25410	COG0446	pyridine nucleotide-disulphide oxidoreductase
NW98_RS25410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NW98_RS25510	COG1215	transferase activity, transferring glycosyl groups
NW98_RS25530	COG0318	PFAM AMP-dependent synthetase and ligase
NW98_RS25570	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS25580	COG0628	permease
NW98_RS25590	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NW98_RS25605	COG1902	pentaerythritol trinitrate reductase activity
NW98_RS25625	COG1309	transcriptional regulator
NW98_RS25655	COG0642	Histidine kinase
NW98_RS25675	COG3842	ATPase activity
NW98_RS25690	COG2207	Transcriptional regulator
NW98_RS25700	COG3971	2-oxopent-4-enoate hydratase activity
NW98_RS25710	COG3384	dioxygenase
NW98_RS25715	COG1012	belongs to the aldehyde dehydrogenase family
NW98_RS25730	COG1846	Transcriptional regulator
NW98_RS25745	COG0745	RESPONSE REGULATOR receiver
NW98_RS25750	COG2205	protein histidine kinase activity
NW98_RS25805	COG2207	Transcriptional regulator
NW98_RS25865	COG1845	cytochrome c oxidase, subunit III
NW98_RS25885	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
NW98_RS25895	COG0477	Major facilitator Superfamily
NW98_RS25905	COG3214	Protein conserved in bacteria
NW98_RS26000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NW98_RS26030	COG0642	Histidine kinase
NW98_RS26110	COG2205	protein histidine kinase activity
NW98_RS26115	COG0745	RESPONSE REGULATOR receiver
NW98_RS26125	COG2066	Belongs to the glutaminase family
NW98_RS26145	COG5295	Hep Hag repeat protein
NW98_RS26185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NW98_RS26190	COG1960	acyl-CoA dehydrogenase activity
NW98_RS26235	COG4638	Rieske (2fe-2S)
NW98_RS26315	COG1477	protein flavinylation
NW98_RS26320	COG1012	belongs to the aldehyde dehydrogenase family
NW98_RS26325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NW98_RS26340	COG0583	DNA-binding transcription factor activity
NW98_RS26355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NW98_RS26380	COG1349	DNA-binding transcription factor activity
NW98_RS26390	COG2271	Major facilitator Superfamily
NW98_RS26400	COG0246	Mannitol dehydrogenase
NW98_RS26410	COG4948	Mandelate Racemase Muconate Lactonizing
NW98_RS26415	COG1063	alcohol dehydrogenase
NW98_RS26450	COG5441	Belongs to the UPF0261 family
NW98_RS26455	COG5564	TIM-barrel signal transduction protein
NW98_RS26490	COG3023	N-Acetylmuramoyl-L-alanine amidase
NW98_RS26500	COG5295	Hep Hag repeat protein
NW98_RS26635	COG0302	gtp cyclohydrolase
NW98_RS26755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NW98_RS26770	COG2916	Histone family protein nucleoid-structuring protein H-NS
NW98_RS26805	COG4790	Type iii secretion
NW98_RS26950	COG0477	Major facilitator Superfamily
NW98_RS26980	COG1280	lysine exporter protein (LysE YggA)
NW98_RS26985	COG1522	sequence-specific DNA binding
NW98_RS27000	COG0306	phosphate transporter
NW98_RS27025	COG0318	PFAM AMP-dependent synthetase and ligase
NW98_RS27065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NW98_RS27075	COG4521	taurine ABC transporter
NW98_RS27080	COG2175	clavaminate synthase activity
NW98_RS27090	COG2194	sulfuric ester hydrolase activity
NW98_RS27095	COG1215	transferase activity, transferring glycosyl groups
NW98_RS27115	COG0457	Tetratricopeptide repeat
NW98_RS27120	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NW98_RS27125	COG1215	transferase activity, transferring glycosyl groups
NW98_RS27140	COG3550	peptidyl-serine autophosphorylation
NW98_RS27270	COG1450	Type ii and iii secretion system protein
NW98_RS27315	COG2207	Transcriptional regulator
NW98_RS27350	COG4794	Type iii secretion
NW98_RS27365	COG4789	Type iii secretion
NW98_RS27370	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NW98_RS27480	COG0028	Belongs to the TPP enzyme family
NW98_RS27485	COG0427	acetyl-CoA hydrolase
NW98_RS27490	COG2030	dehydratase
NW98_RS27500	COG0583	DNA-binding transcription factor activity
NW98_RS27520	COG2814	Major facilitator Superfamily
NW98_RS27530	COG4191	Histidine kinase
NW98_RS27570	COG3621	Patatin-like phospholipase
NW98_RS27610	COG1472	Belongs to the glycosyl hydrolase 3 family
NW98_RS27615	COG1472	Belongs to the glycosyl hydrolase 3 family
NW98_RS27625	COG0154	amidase activity
NW98_RS27645	COG3276	selenocysteine insertion sequence binding
NW98_RS27650	COG1921	L-seryl-tRNASec selenium transferase activity
NW98_RS27660	COG2864	formate dehydrogenase
NW98_RS27665	COG0437	4 iron, 4 sulfur cluster binding
NW98_RS27690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NW98_RS27700	COG1126	abc transporter atp-binding protein
NW98_RS27705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NW98_RS27710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NW98_RS27720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NW98_RS27740	COG3608	succinylglutamate desuccinylase aspartoacylase
NW98_RS27760	COG1295	ribonuclease BN
NW98_RS27765	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS27785	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NW98_RS27785	COG2755	lipolytic protein G-D-S-L family
NW98_RS27795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NW98_RS27810	COG0438	transferase activity, transferring glycosyl groups
NW98_RS27830	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NW98_RS27830	COG2755	lipolytic protein G-D-S-L family
NW98_RS27835	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NW98_RS27880	COG0285	dihydrofolate synthase activity
NW98_RS27885	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NW98_RS27900	COG0133	tryptophan synthase activity
NW98_RS27905	COG0135	phosphoribosylanthranilate isomerase activity
NW98_RS27960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NW98_RS27985	COG1522	sequence-specific DNA binding
NW98_RS28030	COG0372	Belongs to the citrate synthase family
NW98_RS28035	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NW98_RS28040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NW98_RS28045	COG1053	succinate dehydrogenase
NW98_RS28055	COG2009	succinate dehydrogenase
NW98_RS28065	COG2188	Transcriptional regulator
NW98_RS28090	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NW98_RS28095	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
NW98_RS28095	COG3210	domain, Protein
NW98_RS28095	COG3064	Membrane
NW98_RS28100	COG2831	hemolysin activation secretion protein
NW98_RS28125	COG1176	ABC-type spermidine putrescine transport system, permease component I
NW98_RS28135	COG3842	ATPase activity
NW98_RS28155	COG4771	TonB-dependent receptor
NW98_RS28165	COG3038	cytochrome b561
NW98_RS28210	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NW98_RS28215	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NW98_RS28390	COG0583	DNA-binding transcription factor activity
NW98_RS28415	COG0477	Major facilitator Superfamily
NW98_RS28420	COG1104	cysteine desulfurase activity
NW98_RS28435	COG0477	Major facilitator Superfamily
NW98_RS28445	COG0583	DNA-binding transcription factor activity
NW98_RS28455	COG0179	Fumarylacetoacetate (FAA) hydrolase
NW98_RS28500	COG2916	Histone family protein nucleoid-structuring protein H-NS
NW98_RS28520	COG2610	gluconate transmembrane transporter activity
NW98_RS28565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NW98_RS28570	COG0601	transmembrane transport
NW98_RS28595	COG3104	oligopeptide transport
NW98_RS28640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NW98_RS28665	COG2081	HI0933 family
NW98_RS28670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NW98_RS28690	COG0142	geranyltranstransferase activity
NW98_RS28715	COG0412	Dienelactone hydrolase
NW98_RS28735	COG1252	NADH dehydrogenase
NW98_RS28745	COG1611	Belongs to the LOG family
NW98_RS28765	COG1683	Conserved Protein
NW98_RS28805	COG4695	Portal protein
NW98_RS28815	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NW98_RS28840	COG1846	Transcriptional regulator
NW98_RS28845	COG1764	response to oxidative stress
NW98_RS28865	COG0725	ABC transporter, periplasmic molybdate-binding protein
NW98_RS28870	COG4149	molybdate abc transporter
NW98_RS28905	COG0583	DNA-binding transcription factor activity
NW98_RS28920	COG1253	flavin adenine dinucleotide binding
NW98_RS28925	COG0352	thiamine-phosphate diphosphorylase activity
NW98_RS28930	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NW98_RS28950	COG1304	FMN binding
NW98_RS29020	COG0247	lactate metabolic process
NW98_RS29025	COG1592	Rubrerythrin
NW98_RS29035	COG3023	N-Acetylmuramoyl-L-alanine amidase
NW98_RS29050	COG4941	Belongs to the sigma-70 factor family
NW98_RS29060	COG3795	YCII-related domain
NW98_RS29065	COG3795	YCII-related domain
NW98_RS29100	COG0628	permease
NW98_RS29135	COG2130	NADP-dependent
NW98_RS29160	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS29190	COG0583	DNA-binding transcription factor activity
NW98_RS29220	COG2837	iron assimilation
NW98_RS29230	COG5265	(ABC) transporter
NW98_RS29240	COG4977	sequence-specific DNA binding
NW98_RS29275	COG0038	chloride channel
NW98_RS29315	COG0840	transmembrane signaling receptor activity
NW98_RS29320	COG0642	Histidine kinase
NW98_RS29335	COG1012	belongs to the aldehyde dehydrogenase family
NW98_RS29345	COG0025	NhaP-type Na H and K H
NW98_RS29365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NW98_RS29380	COG2146	nitrite reductase [NAD(P)H] activity
NW98_RS29385	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NW98_RS29390	COG4638	Rieske (2fe-2S)
NW98_RS29420	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NW98_RS29445	COG0446	pyridine nucleotide-disulphide oxidoreductase
NW98_RS29445	COG1902	pentaerythritol trinitrate reductase activity
NW98_RS29465	COG0583	DNA-binding transcription factor activity
NW98_RS29470	COG4638	Rieske (2fe-2S)
NW98_RS29475	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NW98_RS29480	COG0543	2 iron, 2 sulfur cluster binding
NW98_RS29480	COG0633	Ferredoxin
NW98_RS29485	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS29505	COG1335	isochorismatase
NW98_RS29610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NW98_RS29640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NW98_RS29660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NW98_RS29690	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS29715	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS29725	COG0438	transferase activity, transferring glycosyl groups
NW98_RS29735	COG2205	protein histidine kinase activity
NW98_RS29735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NW98_RS29735	COG2198	Histidine kinase
NW98_RS29735	COG0784	Response regulator, receiver
NW98_RS29750	COG2204	response regulator
NW98_RS29785	COG2192	nodulation
NW98_RS29790	COG0859	PFAM glycosyl transferase family 9
NW98_RS29795	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NW98_RS29800	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS29810	COG5265	(ABC) transporter
NW98_RS29825	COG0688	phosphatidylethanolamine metabolic process
NW98_RS29830	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NW98_RS29845	COG2084	Dehydrogenase
NW98_RS29850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NW98_RS29860	COG2091	lysine biosynthetic process via aminoadipic acid
NW98_RS29880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NW98_RS29910	COG0022	dehydrogenase e1 component
NW98_RS29970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NW98_RS30030	COG2239	Acts as a magnesium transporter
NW98_RS30045	COG0071	Belongs to the small heat shock protein (HSP20) family
NW98_RS30085	COG2175	clavaminate synthase activity
NW98_RS30090	COG3246	L-lysine catabolic process to acetate
NW98_RS30105	COG0243	molybdopterin cofactor binding
NW98_RS30110	COG0437	4 iron, 4 sulfur cluster binding
NW98_RS30115	COG3302	dmso reductase anchor subunit
NW98_RS30185	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NW98_RS30195	COG0154	amidase activity
NW98_RS30215	COG0454	-acetyltransferase
NW98_RS30215	COG0456	acetyltransferase
NW98_RS30235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NW98_RS30300	COG5001	Diguanylate cyclase
NW98_RS30300	COG3447	MASE1 domain protein
NW98_RS30300	COG5002	protein histidine kinase activity
NW98_RS30345	COG1136	(ABC) transporter
NW98_RS30350	COG2072	flavoprotein involved in K transport
NW98_RS30360	COG1028	Short-chain dehydrogenase reductase Sdr
NW98_RS30385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NW98_RS30395	COG1126	abc transporter atp-binding protein
NW98_RS30400	COG0765	amino acid transport
NW98_RS30405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NW98_RS30420	COG1657	PFAM Prenyltransferase squalene oxidase
NW98_RS30430	COG1562	ergosterol biosynthetic process
NW98_RS30475	COG1595	DNA-templated transcription, initiation
NW98_RS30485	COG1393	Belongs to the ArsC family
NW98_RS30490	COG1192	Involved in chromosome partitioning