locus-tag	class	description
BOC50_RS00030	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS00040	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS00055	COG2721	sulfolactate sulfo-lyase activity
BOC50_RS00065	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOC50_RS00070	COG1129	ABC transporter
BOC50_RS00095	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS00105	COG2814	Major facilitator Superfamily
BOC50_RS00110	COG1022	Amp-dependent synthetase and ligase
BOC50_RS00110	COG3320	Male sterility
BOC50_RS00115	COG1012	belongs to the aldehyde dehydrogenase family
BOC50_RS00120	COG1024	Enoyl-CoA hydratase
BOC50_RS00225	COG3511	phospholipase C
BOC50_RS00230	COG1858	cytochrome C peroxidase
BOC50_RS00240	COG0038	chloride channel
BOC50_RS00275	COG0402	S-adenosylhomocysteine deaminase activity
BOC50_RS00280	COG2508	Transcriptional regulator
BOC50_RS00285	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BOC50_RS00300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS00325	COG0583	DNA-binding transcription factor activity
BOC50_RS00370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS00480	COG1215	transferase activity, transferring glycosyl groups
BOC50_RS00505	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS00545	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS00555	COG0628	permease
BOC50_RS00565	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BOC50_RS00580	COG1902	pentaerythritol trinitrate reductase activity
BOC50_RS00600	COG1309	transcriptional regulator
BOC50_RS00640	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BOC50_RS00645	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BOC50_RS00670	COG1024	Enoyl-CoA hydratase
BOC50_RS00685	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS00705	COG3217	Mosc domain protein beta barrel domain protein
BOC50_RS00705	COG0633	Ferredoxin
BOC50_RS00710	COG0642	Histidine kinase
BOC50_RS00725	COG4208	sulfate ABC transporter
BOC50_RS00730	COG3842	ATPase activity
BOC50_RS00745	COG2207	Transcriptional regulator
BOC50_RS00755	COG3971	2-oxopent-4-enoate hydratase activity
BOC50_RS00765	COG3384	dioxygenase
BOC50_RS00770	COG1012	belongs to the aldehyde dehydrogenase family
BOC50_RS00785	COG1846	Transcriptional regulator
BOC50_RS00800	COG0745	RESPONSE REGULATOR receiver
BOC50_RS00805	COG2205	protein histidine kinase activity
BOC50_RS00855	COG2207	Transcriptional regulator
BOC50_RS00910	COG1845	cytochrome c oxidase, subunit III
BOC50_RS00930	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BOC50_RS00940	COG0477	Major facilitator Superfamily
BOC50_RS00950	COG3214	Protein conserved in bacteria
BOC50_RS00970	COG3291	Pkd domain containing protein
BOC50_RS01115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BOC50_RS01145	COG0642	Histidine kinase
BOC50_RS01230	COG2205	protein histidine kinase activity
BOC50_RS01235	COG0745	RESPONSE REGULATOR receiver
BOC50_RS01245	COG2066	Belongs to the glutaminase family
BOC50_RS01275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOC50_RS01285	COG1538	Outer membrane efflux protein
BOC50_RS01295	COG1024	Enoyl-CoA hydratase
BOC50_RS01300	COG1024	Enoyl-CoA hydratase
BOC50_RS01315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BOC50_RS01320	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS01335	COG0330	HflC and HflK could
BOC50_RS01370	COG0028	Belongs to the TPP enzyme family
BOC50_RS01370	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BOC50_RS01380	COG1012	belongs to the aldehyde dehydrogenase family
BOC50_RS01425	COG2252	PERMEase
BOC50_RS01460	COG3284	Transcriptional regulator
BOC50_RS01500	COG1132	(ABC) transporter
BOC50_RS01505	COG2375	cellular response to nickel ion
BOC50_RS01505	COG1132	(ABC) transporter
BOC50_RS01515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOC50_RS01515	COG3433	isochorismatase activity
BOC50_RS01515	COG2226	methyltransferase
BOC50_RS01520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOC50_RS01520	COG3433	isochorismatase activity
BOC50_RS01520	COG2226	methyltransferase
BOC50_RS01530	COG1021	2,3-dihydroxybenzoate-AMP ligase
BOC50_RS01625	COG0657	acetylesterase activity
BOC50_RS01635	COG1250	3-hydroxyacyl-CoA dehydrogenase
BOC50_RS01640	COG3246	L-lysine catabolic process to acetate
BOC50_RS01680	COG3119	arylsulfatase activity
BOC50_RS01685	COG0583	DNA-binding transcription factor activity
BOC50_RS01700	COG2113	Glycine betaine
BOC50_RS01720	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BOC50_RS01725	COG0247	lactate metabolic process
BOC50_RS01725	COG2181	nitrate reductase activity
BOC50_RS01730	COG0446	pyridine nucleotide-disulphide oxidoreductase
BOC50_RS01730	COG1902	pentaerythritol trinitrate reductase activity
BOC50_RS01775	COG1621	beta-fructofuranosidase activity
BOC50_RS01785	COG1566	PFAM secretion protein HlyD family protein
BOC50_RS01880	COG0477	Major facilitator Superfamily
BOC50_RS01890	COG0784	Response regulator, receiver
BOC50_RS01895	COG4251	negative regulation of phosphorylation
BOC50_RS01910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BOC50_RS01940	COG1278	Cold shock
BOC50_RS01980	COG0446	pyridine nucleotide-disulphide oxidoreductase
BOC50_RS01980	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BOC50_RS01995	COG1760	l-serine dehydratase
BOC50_RS02040	COG1294	oxidase, subunit
BOC50_RS02045	COG1271	oxidase subunit
BOC50_RS02060	COG1285	pathogenesis
BOC50_RS02090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BOC50_RS02100	COG4644	lycopene metabolic process
BOC50_RS02135	COG1450	Type ii and iii secretion system protein
BOC50_RS02140	COG2207	Transcriptional regulator
BOC50_RS02185	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BOC50_RS02190	COG4789	Type iii secretion
BOC50_RS02270	COG2186	Transcriptional regulator
BOC50_RS02275	COG2084	Dehydrogenase
BOC50_RS02280	COG3395	kinase activity
BOC50_RS02285	COG0235	Class ii aldolase
BOC50_RS02290	COG2271	Major facilitator Superfamily
BOC50_RS02295	COG3622	Belongs to the hyi family
BOC50_RS02300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BOC50_RS02350	COG4175	Glycine betaine
BOC50_RS02390	COG0640	Transcriptional regulator
BOC50_RS02405	COG0798	PFAM Bile acid sodium symporter
BOC50_RS02505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BOC50_RS02510	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS02560	COG4638	Rieske (2fe-2S)
BOC50_RS02595	COG2271	Major facilitator Superfamily
BOC50_RS02640	COG1477	protein flavinylation
BOC50_RS02645	COG1012	belongs to the aldehyde dehydrogenase family
BOC50_RS02650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BOC50_RS02665	COG0583	DNA-binding transcription factor activity
BOC50_RS02680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOC50_RS02705	COG1349	DNA-binding transcription factor activity
BOC50_RS02715	COG2271	Major facilitator Superfamily
BOC50_RS02725	COG0246	Mannitol dehydrogenase
BOC50_RS02735	COG4948	Mandelate Racemase Muconate Lactonizing
BOC50_RS02740	COG1063	alcohol dehydrogenase
BOC50_RS02775	COG5441	Belongs to the UPF0261 family
BOC50_RS02780	COG5564	TIM-barrel signal transduction protein
BOC50_RS02815	COG3023	N-Acetylmuramoyl-L-alanine amidase
BOC50_RS02825	COG5295	Hep Hag repeat protein
BOC50_RS02965	COG0302	gtp cyclohydrolase
BOC50_RS03045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BOC50_RS03060	COG2916	Histone family protein nucleoid-structuring protein H-NS
BOC50_RS03095	COG4790	Type iii secretion
BOC50_RS03240	COG0477	Major facilitator Superfamily
BOC50_RS03270	COG1280	lysine exporter protein (LysE YggA)
BOC50_RS03275	COG1522	sequence-specific DNA binding
BOC50_RS03285	COG0306	phosphate transporter
BOC50_RS03310	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS03345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BOC50_RS03355	COG4521	taurine ABC transporter
BOC50_RS03365	COG2175	clavaminate synthase activity
BOC50_RS03375	COG2194	sulfuric ester hydrolase activity
BOC50_RS03380	COG1215	transferase activity, transferring glycosyl groups
BOC50_RS03400	COG0457	Tetratricopeptide repeat
BOC50_RS03405	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BOC50_RS03410	COG1215	transferase activity, transferring glycosyl groups
BOC50_RS03425	COG3550	peptidyl-serine autophosphorylation
BOC50_RS03555	COG1450	Type ii and iii secretion system protein
BOC50_RS03605	COG2207	Transcriptional regulator
BOC50_RS03640	COG4794	Type iii secretion
BOC50_RS03645	COG4790	Type iii secretion
BOC50_RS03660	COG4789	Type iii secretion
BOC50_RS03665	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BOC50_RS03775	COG0028	Belongs to the TPP enzyme family
BOC50_RS03780	COG0427	acetyl-CoA hydrolase
BOC50_RS03785	COG2030	dehydratase
BOC50_RS03795	COG0583	DNA-binding transcription factor activity
BOC50_RS03815	COG2814	Major facilitator Superfamily
BOC50_RS03830	COG4191	Histidine kinase
BOC50_RS03870	COG3621	Patatin-like phospholipase
BOC50_RS03910	COG1472	Belongs to the glycosyl hydrolase 3 family
BOC50_RS03920	COG0154	amidase activity
BOC50_RS03945	COG3276	selenocysteine insertion sequence binding
BOC50_RS03950	COG1921	L-seryl-tRNASec selenium transferase activity
BOC50_RS03960	COG2864	formate dehydrogenase
BOC50_RS03965	COG0437	4 iron, 4 sulfur cluster binding
BOC50_RS03995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOC50_RS04005	COG1126	abc transporter atp-binding protein
BOC50_RS04010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BOC50_RS04015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BOC50_RS04025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOC50_RS04050	COG3608	succinylglutamate desuccinylase aspartoacylase
BOC50_RS04080	COG1295	ribonuclease BN
BOC50_RS04085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS04110	COG2755	lipolytic protein G-D-S-L family
BOC50_RS04110	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BOC50_RS04120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BOC50_RS04135	COG0438	transferase activity, transferring glycosyl groups
BOC50_RS04155	COG2755	lipolytic protein G-D-S-L family
BOC50_RS04155	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BOC50_RS04160	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BOC50_RS04165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BOC50_RS04200	COG0285	dihydrofolate synthase activity
BOC50_RS04205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BOC50_RS04220	COG0133	tryptophan synthase activity
BOC50_RS04225	COG0135	phosphoribosylanthranilate isomerase activity
BOC50_RS04280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BOC50_RS04305	COG1522	sequence-specific DNA binding
BOC50_RS04335	COG0372	Belongs to the citrate synthase family
BOC50_RS04340	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BOC50_RS04345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BOC50_RS04350	COG1053	succinate dehydrogenase
BOC50_RS04360	COG2009	succinate dehydrogenase
BOC50_RS04370	COG2188	Transcriptional regulator
BOC50_RS04395	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BOC50_RS04400	COG3064	Membrane
BOC50_RS04400	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BOC50_RS04400	COG3210	domain, Protein
BOC50_RS04405	COG2831	hemolysin activation secretion protein
BOC50_RS04465	COG1177	transmembrane transport
BOC50_RS04470	COG1176	ABC-type spermidine putrescine transport system, permease component I
BOC50_RS04480	COG3842	ATPase activity
BOC50_RS04500	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BOC50_RS04505	COG4774	siderophore transport
BOC50_RS04515	COG3038	cytochrome b561
BOC50_RS04560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BOC50_RS04565	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BOC50_RS04590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BOC50_RS04615	COG2081	HI0933 family
BOC50_RS04645	COG0142	geranyltranstransferase activity
BOC50_RS04675	COG0412	Dienelactone hydrolase
BOC50_RS04695	COG1252	NADH dehydrogenase
BOC50_RS04705	COG1611	Belongs to the LOG family
BOC50_RS04730	COG1683	Conserved Protein
BOC50_RS04770	COG4695	Portal protein
BOC50_RS04780	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BOC50_RS04805	COG1846	Transcriptional regulator
BOC50_RS04810	COG1764	response to oxidative stress
BOC50_RS04835	COG0725	ABC transporter, periplasmic molybdate-binding protein
BOC50_RS04840	COG4149	molybdate abc transporter
BOC50_RS04875	COG0583	DNA-binding transcription factor activity
BOC50_RS04890	COG1253	flavin adenine dinucleotide binding
BOC50_RS04895	COG0352	thiamine-phosphate diphosphorylase activity
BOC50_RS04900	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BOC50_RS04985	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BOC50_RS05005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOC50_RS05045	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BOC50_RS05050	COG5654	RES domain protein
BOC50_RS05055	COG5642	Protein of unknown function (DUF2384)
BOC50_RS05080	COG0438	transferase activity, transferring glycosyl groups
BOC50_RS05085	COG0438	transferase activity, transferring glycosyl groups
BOC50_RS05105	COG3206	protein involved in exopolysaccharide biosynthesis
BOC50_RS05105	COG0489	protein tyrosine kinase activity
BOC50_RS05125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BOC50_RS05155	COG0247	lactate metabolic process
BOC50_RS05160	COG1592	Rubrerythrin
BOC50_RS05170	COG3023	N-Acetylmuramoyl-L-alanine amidase
BOC50_RS05185	COG4941	Belongs to the sigma-70 factor family
BOC50_RS05195	COG3795	YCII-related domain
BOC50_RS05200	COG3795	YCII-related domain
BOC50_RS05235	COG0628	permease
BOC50_RS05270	COG2130	NADP-dependent
BOC50_RS05300	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS05325	COG0583	DNA-binding transcription factor activity
BOC50_RS05355	COG2837	iron assimilation
BOC50_RS05370	COG5265	(ABC) transporter
BOC50_RS05380	COG4977	sequence-specific DNA binding
BOC50_RS05415	COG0038	chloride channel
BOC50_RS05455	COG0840	transmembrane signaling receptor activity
BOC50_RS05460	COG0642	Histidine kinase
BOC50_RS05475	COG1012	belongs to the aldehyde dehydrogenase family
BOC50_RS05485	COG0025	NhaP-type Na H and K H
BOC50_RS05490	COG2733	membrane
BOC50_RS05505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BOC50_RS05520	COG2146	nitrite reductase [NAD(P)H] activity
BOC50_RS05525	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BOC50_RS05530	COG4638	Rieske (2fe-2S)
BOC50_RS05560	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BOC50_RS05590	COG1902	pentaerythritol trinitrate reductase activity
BOC50_RS05590	COG0446	pyridine nucleotide-disulphide oxidoreductase
BOC50_RS05610	COG0583	DNA-binding transcription factor activity
BOC50_RS05615	COG4638	Rieske (2fe-2S)
BOC50_RS05620	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BOC50_RS05625	COG0543	2 iron, 2 sulfur cluster binding
BOC50_RS05625	COG0633	Ferredoxin
BOC50_RS05630	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS05650	COG1335	isochorismatase
BOC50_RS05675	COG0833	amino acid
BOC50_RS05705	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BOC50_RS05715	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS05725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BOC50_RS05760	COG1611	Belongs to the LOG family
BOC50_RS05800	COG0840	transmembrane signaling receptor activity
BOC50_RS05830	COG1136	(ABC) transporter
BOC50_RS05845	COG0589	response to stress
BOC50_RS05865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOC50_RS05870	COG0842	Transport permease protein
BOC50_RS05870	COG1129	ABC transporter
BOC50_RS05875	COG0842	Transport permease protein
BOC50_RS05880	COG4191	Histidine kinase
BOC50_RS05880	COG0784	Response regulator, receiver
BOC50_RS05895	COG0840	transmembrane signaling receptor activity
BOC50_RS05920	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BOC50_RS05925	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BOC50_RS05930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BOC50_RS05930	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BOC50_RS05940	COG0356	it plays a direct role in the translocation of protons across the membrane
BOC50_RS05955	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BOC50_RS05970	COG3243	poly(R)-hydroxyalkanoic acid synthase
BOC50_RS05975	COG0280	phosphate acetyltransferase
BOC50_RS05980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BOC50_RS06000	COG2823	Periplasmic or secreted lipoprotein
BOC50_RS06010	COG0295	cytidine deaminase activity
BOC50_RS06045	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BOC50_RS06050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BOC50_RS06070	COG0625	glutathione transferase activity
BOC50_RS06105	COG0596	Alpha beta hydrolase
BOC50_RS06260	COG1573	uracil-dna glycosylase
BOC50_RS06265	COG2936	dipeptidyl-peptidase activity
BOC50_RS06275	COG1404	Belongs to the peptidase S8 family
BOC50_RS06345	COG0672	)-iron permease
BOC50_RS06360	COG0504	CTP synthase activity
BOC50_RS06465	COG1215	transferase activity, transferring glycosyl groups
BOC50_RS06495	COG0583	DNA-binding transcription factor activity
BOC50_RS06500	COG1253	flavin adenine dinucleotide binding
BOC50_RS06555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BOC50_RS06575	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS06585	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS06590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BOC50_RS06595	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS06610	COG3246	L-lysine catabolic process to acetate
BOC50_RS06620	COG1022	Amp-dependent synthetase and ligase
BOC50_RS06735	COG3209	COG3209 Rhs family protein
BOC50_RS06880	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS06890	COG3048	D-serine ammonia-lyase activity
BOC50_RS06895	COG0583	DNA-binding transcription factor activity
BOC50_RS06920	COG0477	Major facilitator Superfamily
BOC50_RS06925	COG1104	cysteine desulfurase activity
BOC50_RS06945	COG0477	Major facilitator Superfamily
BOC50_RS06950	COG0583	DNA-binding transcription factor activity
BOC50_RS06960	COG0179	Fumarylacetoacetate (FAA) hydrolase
BOC50_RS07005	COG2916	Histone family protein nucleoid-structuring protein H-NS
BOC50_RS07025	COG2610	gluconate transmembrane transporter activity
BOC50_RS07070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOC50_RS07075	COG0601	transmembrane transport
BOC50_RS07100	COG3104	oligopeptide transport
BOC50_RS07130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOC50_RS07180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BOC50_RS07210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BOC50_RS07230	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BOC50_RS07255	COG2879	small protein
BOC50_RS07260	COG1966	Carbon starvation protein
BOC50_RS07310	COG0463	Glycosyl transferase, family 2
BOC50_RS07360	COG4964	Belongs to the GSP D family
BOC50_RS07435	COG2271	Major facilitator Superfamily
BOC50_RS07510	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BOC50_RS07520	COG3546	catalase activity
BOC50_RS07525	COG3685	Protein conserved in bacteria
BOC50_RS07605	COG0516	GMP reductase activity
BOC50_RS07605	COG0517	IMP dehydrogenase activity
BOC50_RS07625	COG1573	uracil-dna glycosylase
BOC50_RS07630	COG1914	H( )-stimulated, divalent metal cation uptake system
BOC50_RS07650	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS07675	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS07680	COG2823	Periplasmic or secreted lipoprotein
BOC50_RS07700	COG2198	Histidine kinase
BOC50_RS07700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOC50_RS07700	COG0784	Response regulator, receiver
BOC50_RS07700	COG2205	protein histidine kinase activity
BOC50_RS07715	COG2204	response regulator
BOC50_RS07750	COG2192	nodulation
BOC50_RS07755	COG0859	PFAM glycosyl transferase family 9
BOC50_RS07760	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BOC50_RS07765	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS07775	COG5265	(ABC) transporter
BOC50_RS07790	COG0688	phosphatidylethanolamine metabolic process
BOC50_RS07795	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BOC50_RS07810	COG2084	Dehydrogenase
BOC50_RS07815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BOC50_RS07825	COG2091	lysine biosynthetic process via aminoadipic acid
BOC50_RS07845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BOC50_RS07875	COG0022	dehydrogenase e1 component
BOC50_RS07935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BOC50_RS07995	COG2239	Acts as a magnesium transporter
BOC50_RS08010	COG0071	Belongs to the small heat shock protein (HSP20) family
BOC50_RS08035	COG2909	trisaccharide binding
BOC50_RS08050	COG2175	clavaminate synthase activity
BOC50_RS08055	COG3246	L-lysine catabolic process to acetate
BOC50_RS08080	COG0243	molybdopterin cofactor binding
BOC50_RS08085	COG0437	4 iron, 4 sulfur cluster binding
BOC50_RS08090	COG3302	dmso reductase anchor subunit
BOC50_RS08160	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS08170	COG0154	amidase activity
BOC50_RS08195	COG0456	acetyltransferase
BOC50_RS08195	COG0454	-acetyltransferase
BOC50_RS08260	COG3447	MASE1 domain protein
BOC50_RS08260	COG5001	Diguanylate cyclase
BOC50_RS08260	COG5002	protein histidine kinase activity
BOC50_RS08305	COG1136	(ABC) transporter
BOC50_RS08310	COG2072	flavoprotein involved in K transport
BOC50_RS08320	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS08345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BOC50_RS08355	COG1126	abc transporter atp-binding protein
BOC50_RS08360	COG0765	amino acid transport
BOC50_RS08365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOC50_RS08380	COG1657	PFAM Prenyltransferase squalene oxidase
BOC50_RS08390	COG1562	ergosterol biosynthetic process
BOC50_RS08440	COG1595	DNA-templated transcription, initiation
BOC50_RS08450	COG1393	Belongs to the ArsC family
BOC50_RS08460	COG1192	Involved in chromosome partitioning
BOC50_RS08500	COG1396	sequence-specific DNA binding
BOC50_RS08525	COG1309	transcriptional regulator
BOC50_RS08550	COG0473	3-isopropylmalate dehydrogenase activity
BOC50_RS08555	COG0583	DNA-binding transcription factor activity
BOC50_RS08575	COG0625	glutathione transferase activity
BOC50_RS08600	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS08610	COG0671	phosphoesterase, PA-phosphatase related
BOC50_RS08670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BOC50_RS08685	COG0583	DNA-binding transcription factor activity
BOC50_RS08690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BOC50_RS08695	COG0589	response to stress
BOC50_RS08745	COG1045	serine acetyltransferase
BOC50_RS08755	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS08760	COG0302	gtp cyclohydrolase
BOC50_RS08780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BOC50_RS08785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BOC50_RS08790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BOC50_RS08795	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BOC50_RS08890	COG1595	DNA-templated transcription, initiation
BOC50_RS08895	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BOC50_RS08930	COG2916	Histone family protein nucleoid-structuring protein H-NS
BOC50_RS08945	COG0477	Major facilitator Superfamily
BOC50_RS09035	COG1176	ABC-type spermidine putrescine transport system, permease component I
BOC50_RS09040	COG1177	transmembrane transport
BOC50_RS09080	COG0432	Pfam Uncharacterised protein family UPF0047
BOC50_RS09120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BOC50_RS09150	COG5295	Hep Hag repeat protein
BOC50_RS09175	COG3121	Chaperone
BOC50_RS09180	COG3188	usher protein
BOC50_RS09195	COG2885	chlorophyll binding
BOC50_RS09335	COG3188	usher protein
BOC50_RS09370	COG2271	Major facilitator Superfamily
BOC50_RS09375	COG1929	Belongs to the glycerate kinase type-1 family
BOC50_RS09380	COG0469	pyruvate kinase activity
BOC50_RS09385	COG3835	regulator
BOC50_RS09395	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS09395	COG0300	oxidoreductase activity
BOC50_RS09395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOC50_RS09395	COG3321	synthase
BOC50_RS09395	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS09430	COG2203	Gaf domain
BOC50_RS09430	COG3706	GGDEF domain
BOC50_RS09430	COG4251	negative regulation of phosphorylation
BOC50_RS09430	COG5001	Diguanylate cyclase
BOC50_RS09475	COG1879	ABC-type sugar transport system periplasmic component
BOC50_RS09480	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOC50_RS09515	COG0513	Belongs to the DEAD box helicase family
BOC50_RS09530	COG1473	amidohydrolase
BOC50_RS09535	COG0583	DNA-binding transcription factor activity
BOC50_RS09590	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS09620	COG3537	Alpha-1,2-mannosidase
BOC50_RS09645	COG0367	asparagine synthase
BOC50_RS09685	COG2885	chlorophyll binding
BOC50_RS09795	COG0583	DNA-binding transcription factor activity
BOC50_RS09850	COG1984	allophanate hydrolase subunit 2
BOC50_RS09865	COG0511	ligase activity, forming carbon-carbon bonds
BOC50_RS09870	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BOC50_RS09930	COG0840	transmembrane signaling receptor activity
BOC50_RS09995	COG0535	radical SAM domain protein
BOC50_RS10005	COG0840	transmembrane signaling receptor activity
BOC50_RS10030	COG1285	pathogenesis
BOC50_RS10115	COG0346	lactoylglutathione lyase activity
BOC50_RS10125	COG1562	ergosterol biosynthetic process
BOC50_RS10135	COG0583	DNA-binding transcription factor activity
BOC50_RS10155	COG1294	oxidase, subunit
BOC50_RS10160	COG1271	oxidase subunit
BOC50_RS10170	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BOC50_RS10185	COG2860	membrane
BOC50_RS10190	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BOC50_RS10200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BOC50_RS10210	COG4558	Periplasmic binding protein
BOC50_RS10215	COG3720	iron ion transport
BOC50_RS10245	COG3842	ATPase activity
BOC50_RS10250	COG1840	ABC-type Fe3 transport system, periplasmic component
BOC50_RS10275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS10285	COG0698	ribose 5-phosphate isomerase
BOC50_RS10290	COG1129	ABC transporter
BOC50_RS10295	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOC50_RS10300	COG1879	ABC-type sugar transport system periplasmic component
BOC50_RS10305	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS10310	COG1063	alcohol dehydrogenase
BOC50_RS10315	COG2376	Dihydroxyacetone kinase
BOC50_RS10345	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS10365	COG2755	lipolytic protein G-D-S-L family
BOC50_RS10365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BOC50_RS10380	COG0583	DNA-binding transcription factor activity
BOC50_RS10385	COG1473	amidohydrolase
BOC50_RS10405	COG1309	transcriptional regulator
BOC50_RS10410	COG1414	Transcriptional regulator
BOC50_RS10420	COG0183	Belongs to the thiolase family
BOC50_RS10435	COG0840	transmembrane signaling receptor activity
BOC50_RS10480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BOC50_RS10490	COG1288	antiporter activity
BOC50_RS10495	COG1414	Transcriptional regulator
BOC50_RS10520	COG0709	Synthesizes selenophosphate from selenide and ATP
BOC50_RS10565	COG0583	DNA-binding transcription factor activity
BOC50_RS10570	COG0657	acetylesterase activity
BOC50_RS10575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOC50_RS10590	COG1301	dicarboxylic acid transport
BOC50_RS10635	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS10640	COG0019	diaminopimelate decarboxylase activity
BOC50_RS10650	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BOC50_RS10655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOC50_RS10655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BOC50_RS10655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BOC50_RS10655	COG3321	synthase
BOC50_RS10655	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS10665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BOC50_RS10705	COG2197	response regulator
BOC50_RS10725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BOC50_RS10730	COG2011	ABC-type metal ion transport system permease component
BOC50_RS10760	COG2186	Transcriptional regulator
BOC50_RS10765	COG0247	lactate metabolic process
BOC50_RS10770	COG1139	Iron-sulfur cluster binding protein
BOC50_RS10775	COG1556	Lactate utilization protein
BOC50_RS10780	COG1620	l-lactate permease
BOC50_RS10790	COG2259	Doxx family
BOC50_RS10815	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BOC50_RS10825	COG0531	amino acid
BOC50_RS10835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BOC50_RS10850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOC50_RS10875	COG3547	Transposase (IS116 IS110 IS902 family)
BOC50_RS10890	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BOC50_RS10895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BOC50_RS10900	COG2271	Major facilitator Superfamily
BOC50_RS10925	COG1176	ABC-type spermidine putrescine transport system, permease component I
BOC50_RS10940	COG1012	belongs to the aldehyde dehydrogenase family
BOC50_RS10995	COG0789	Transcriptional regulator
BOC50_RS11015	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BOC50_RS11020	COG0667	Aldo Keto reductase
BOC50_RS11025	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS11040	COG0556	nucleotide-excision repair
BOC50_RS11050	COG4633	Protein conserved in bacteria
BOC50_RS11055	COG0672	)-iron permease
BOC50_RS11065	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BOC50_RS11115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BOC50_RS11150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BOC50_RS11235	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BOC50_RS11285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BOC50_RS11335	COG0583	DNA-binding transcription factor activity
BOC50_RS11340	COG1741	Belongs to the pirin family
BOC50_RS11380	COG2814	Major facilitator Superfamily
BOC50_RS11390	COG0583	DNA-binding transcription factor activity
BOC50_RS11395	COG1335	isochorismatase
BOC50_RS11405	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BOC50_RS11430	COG0583	DNA-binding transcription factor activity
BOC50_RS11445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BOC50_RS11455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BOC50_RS11490	COG1796	DNA polymerase
BOC50_RS11490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BOC50_RS11535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOC50_RS11540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOC50_RS11550	COG1177	transmembrane transport
BOC50_RS11555	COG1176	ABC-type spermidine putrescine transport system, permease component I
BOC50_RS11560	COG3842	ATPase activity
BOC50_RS11575	COG0174	glutamine synthetase
BOC50_RS11580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BOC50_RS11595	COG1396	sequence-specific DNA binding
BOC50_RS11595	COG1917	Cupin 2, conserved barrel domain protein
BOC50_RS11600	COG1012	belongs to the aldehyde dehydrogenase family
BOC50_RS11605	COG0010	Belongs to the arginase family
BOC50_RS11615	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BOC50_RS11650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BOC50_RS11670	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS11700	COG3634	alkyl hydroperoxide reductase activity
BOC50_RS11720	COG0778	Nitroreductase
BOC50_RS11730	COG2308	Evidence 4 Homologs of previously reported genes of
BOC50_RS11760	COG1305	Transglutaminase-like
BOC50_RS11765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BOC50_RS11785	COG4977	sequence-specific DNA binding
BOC50_RS11795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BOC50_RS11800	COG0028	Belongs to the TPP enzyme family
BOC50_RS11800	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BOC50_RS11965	COG2814	Major facilitator Superfamily
BOC50_RS12000	COG1566	PFAM secretion protein HlyD family protein
BOC50_RS12010	COG1505	serine-type exopeptidase activity
BOC50_RS12025	COG1045	serine acetyltransferase
BOC50_RS12035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BOC50_RS12040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BOC50_RS12045	COG3038	cytochrome b561
BOC50_RS12055	COG0640	Transcriptional regulator
BOC50_RS12070	COG0456	acetyltransferase
BOC50_RS12095	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BOC50_RS12100	COG1858	cytochrome C peroxidase
BOC50_RS12115	COG2814	Major facilitator Superfamily
BOC50_RS12120	COG2188	Transcriptional regulator
BOC50_RS12175	COG0277	FAD linked oxidase domain protein
BOC50_RS12185	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BOC50_RS12195	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BOC50_RS12240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BOC50_RS12250	COG1446	asparaginase
BOC50_RS12255	COG4172	Belongs to the ABC transporter superfamily
BOC50_RS12265	COG0747	negative chemotaxis
BOC50_RS12270	COG0601	transmembrane transport
BOC50_RS12275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOC50_RS12295	COG3485	protocatechuate 3,4-dioxygenase
BOC50_RS12300	COG3485	protocatechuate 3,4-dioxygenase
BOC50_RS12305	COG0583	DNA-binding transcription factor activity
BOC50_RS12320	COG4251	negative regulation of phosphorylation
BOC50_RS12320	COG3706	GGDEF domain
BOC50_RS12320	COG5001	Diguanylate cyclase
BOC50_RS12320	COG2203	Gaf domain
BOC50_RS12330	COG4122	O-methyltransferase activity
BOC50_RS12335	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BOC50_RS12355	COG0531	amino acid
BOC50_RS12365	COG1201	RNA secondary structure unwinding
BOC50_RS12410	COG2274	protein secretion by the type I secretion system
BOC50_RS12450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BOC50_RS12480	COG1739	Uncharacterized protein family UPF0029
BOC50_RS12500	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS12540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOC50_RS12605	COG1979	alcohol dehydrogenase
BOC50_RS12610	COG2130	NADP-dependent
BOC50_RS12650	COG0583	DNA-binding transcription factor activity
BOC50_RS12665	COG0583	DNA-binding transcription factor activity
BOC50_RS12670	COG0477	Major facilitator Superfamily
BOC50_RS12715	COG0302	gtp cyclohydrolase
BOC50_RS12725	COG1116	anion transmembrane transporter activity
BOC50_RS12725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BOC50_RS12730	COG3707	response regulator
BOC50_RS12755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BOC50_RS12760	COG2146	nitrite reductase [NAD(P)H] activity
BOC50_RS12790	COG1070	Carbohydrate kinase
BOC50_RS12800	COG3842	ATPase activity
BOC50_RS12805	COG1063	alcohol dehydrogenase
BOC50_RS12845	COG2223	nitrite transmembrane transporter activity
BOC50_RS12850	COG1349	DNA-binding transcription factor activity
BOC50_RS12910	COG4651	solute:proton antiporter activity
BOC50_RS12910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BOC50_RS12915	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS12940	COG0840	transmembrane signaling receptor activity
BOC50_RS12955	COG0352	thiamine-phosphate diphosphorylase activity
BOC50_RS12960	COG0477	Major facilitator Superfamily
BOC50_RS13035	COG0540	Belongs to the ATCase OTCase family
BOC50_RS13055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BOC50_RS13115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BOC50_RS13120	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS13185	COG0475	glutathione-regulated potassium exporter activity
BOC50_RS13205	COG0339	signal peptide processing
BOC50_RS13210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOC50_RS13235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BOC50_RS13255	COG2175	clavaminate synthase activity
BOC50_RS13275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BOC50_RS13295	COG3851	Histidine kinase
BOC50_RS13305	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BOC50_RS13310	COG1140	nitrate reductase beta subunit
BOC50_RS13315	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BOC50_RS13320	COG2181	nitrate reductase activity
BOC50_RS13325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BOC50_RS13365	COG0651	ATP synthesis coupled electron transport
BOC50_RS13370	COG0650	Formate hydrogenlyase subunit 4
BOC50_RS13380	COG0651	ATP synthesis coupled electron transport
BOC50_RS13385	COG0649	NAD binding
BOC50_RS13390	COG3260	NADH ubiquinone oxidoreductase 20
BOC50_RS13445	COG1695	Transcriptional regulator
BOC50_RS13450	COG0446	pyridine nucleotide-disulphide oxidoreductase
BOC50_RS13450	COG1902	pentaerythritol trinitrate reductase activity
BOC50_RS13495	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BOC50_RS13495	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BOC50_RS13500	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BOC50_RS13515	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BOC50_RS13530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOC50_RS13535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOC50_RS13595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BOC50_RS13635	COG2264	protein methyltransferase activity
BOC50_RS13685	COG0443	Heat shock 70 kDa protein
BOC50_RS13690	COG0443	Heat shock 70 kDa protein
BOC50_RS13730	COG0686	Belongs to the AlaDH PNT family
BOC50_RS13825	COG2271	Major facilitator Superfamily
BOC50_RS13835	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS13865	COG1129	ABC transporter
BOC50_RS13870	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOC50_RS13875	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOC50_RS13880	COG4774	siderophore transport
BOC50_RS13885	COG3712	iron ion homeostasis
BOC50_RS13890	COG1595	DNA-templated transcription, initiation
BOC50_RS13910	COG2353	YceI-like domain
BOC50_RS13940	COG0179	Fumarylacetoacetate (FAA) hydrolase
BOC50_RS13965	COG0387	Pfam Sodium calcium exchanger
BOC50_RS13975	COG0583	DNA-binding transcription factor activity
BOC50_RS14015	COG4221	oxidoreductase activity
BOC50_RS14015	COG0300	oxidoreductase activity
BOC50_RS14015	COG3321	synthase
BOC50_RS14015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BOC50_RS14020	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS14020	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS14020	COG0300	oxidoreductase activity
BOC50_RS14020	COG3321	synthase
BOC50_RS14020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOC50_RS14025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BOC50_RS14025	COG0300	oxidoreductase activity
BOC50_RS14025	COG4221	oxidoreductase activity
BOC50_RS14025	COG3321	synthase
BOC50_RS14030	COG4221	oxidoreductase activity
BOC50_RS14030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOC50_RS14030	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS14030	COG3321	synthase
BOC50_RS14040	COG0569	domain protein
BOC50_RS14040	COG0475	glutathione-regulated potassium exporter activity
BOC50_RS14045	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BOC50_RS14045	COG2070	2-Nitropropane dioxygenase
BOC50_RS14070	COG3425	synthase
BOC50_RS14075	COG1024	Enoyl-CoA hydratase
BOC50_RS14080	COG1024	Enoyl-CoA hydratase
BOC50_RS14085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BOC50_RS14090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BOC50_RS14110	COG2207	Transcriptional regulator
BOC50_RS14115	COG0500	methyltransferase
BOC50_RS14140	COG3275	phosphorelay sensor kinase activity
BOC50_RS14200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BOC50_RS14205	COG4598	ABC transporter
BOC50_RS14210	COG4160	amino acid transport
BOC50_RS14235	COG2259	Doxx family
BOC50_RS14260	COG1404	Belongs to the peptidase S8 family
BOC50_RS14280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BOC50_RS14285	COG0243	molybdopterin cofactor binding
BOC50_RS14290	COG3781	membrane
BOC50_RS14295	COG4682	membrane
BOC50_RS14305	COG1914	H( )-stimulated, divalent metal cation uptake system
BOC50_RS14310	COG2140	Oxalate decarboxylase
BOC50_RS14355	COG3209	COG3209 Rhs family protein
BOC50_RS14390	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BOC50_RS14400	COG0601	transmembrane transport
BOC50_RS14405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOC50_RS14430	COG0583	DNA-binding transcription factor activity
BOC50_RS14465	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS14510	COG0596	Alpha beta hydrolase
BOC50_RS14515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BOC50_RS14535	COG0840	transmembrane signaling receptor activity
BOC50_RS14560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BOC50_RS14590	COG0596	Alpha beta hydrolase
BOC50_RS14670	COG1522	sequence-specific DNA binding
BOC50_RS14680	COG0154	amidase activity
BOC50_RS14710	COG0477	Major facilitator Superfamily
BOC50_RS14725	COG1012	belongs to the aldehyde dehydrogenase family
BOC50_RS14735	COG0028	Belongs to the TPP enzyme family
BOC50_RS14740	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS14745	COG1414	Transcriptional regulator
BOC50_RS14775	COG2146	nitrite reductase [NAD(P)H] activity
BOC50_RS14785	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS14790	COG1414	Transcriptional regulator
BOC50_RS14805	COG1408	metallophosphoesterase
BOC50_RS14815	COG1285	pathogenesis
BOC50_RS14820	COG2197	response regulator
BOC50_RS14845	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BOC50_RS14850	COG0516	GMP reductase activity
BOC50_RS14850	COG0517	IMP dehydrogenase activity
BOC50_RS14865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BOC50_RS14880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS14895	COG1902	pentaerythritol trinitrate reductase activity
BOC50_RS14915	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS14930	COG0531	amino acid
BOC50_RS14935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BOC50_RS14940	COG1012	belongs to the aldehyde dehydrogenase family
BOC50_RS14975	COG0583	DNA-binding transcription factor activity
BOC50_RS14985	COG0583	DNA-binding transcription factor activity
BOC50_RS15030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BOC50_RS15090	COG2916	Histone family protein nucleoid-structuring protein H-NS
BOC50_RS15105	COG1113	amino acid transport
BOC50_RS15120	COG4221	oxidoreductase activity
BOC50_RS15150	COG1063	alcohol dehydrogenase
BOC50_RS15160	COG0589	response to stress
BOC50_RS15220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BOC50_RS15235	COG3291	Pkd domain containing protein
BOC50_RS15255	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BOC50_RS15260	COG2175	clavaminate synthase activity
BOC50_RS15280	COG0495	leucyl-tRNA aminoacylation
BOC50_RS15310	COG2373	Large extracellular alpha-helical protein
BOC50_RS15315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BOC50_RS15325	COG2201	protein-glutamate methylesterase activity
BOC50_RS15330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOC50_RS15330	COG4191	Histidine kinase
BOC50_RS15385	COG1448	Aminotransferase
BOC50_RS15400	COG1522	sequence-specific DNA binding
BOC50_RS15425	COG1272	protein, Hemolysin III
BOC50_RS15480	COG2916	Histone family protein nucleoid-structuring protein H-NS
BOC50_RS15510	COG1414	Transcriptional regulator
BOC50_RS15535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BOC50_RS15545	COG1104	cysteine desulfurase activity
BOC50_RS15550	COG0822	iron-sulfur transferase activity
BOC50_RS15555	COG0316	Belongs to the HesB IscA family
BOC50_RS15575	COG2975	iron-sulfur cluster assembly
BOC50_RS15605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BOC50_RS15625	COG1136	(ABC) transporter
BOC50_RS15630	COG0084	hydrolase, TatD family'
BOC50_RS15635	COG0658	competence protein
BOC50_RS15635	COG2333	competence protein COMEC
BOC50_RS15640	COG2267	carboxylic ester hydrolase activity
BOC50_RS15665	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BOC50_RS15675	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BOC50_RS15685	COG2833	Protein of unknown function (DUF455)
BOC50_RS15695	COG0596	Alpha beta hydrolase
BOC50_RS15705	COG0613	PHP domain protein
BOC50_RS15710	COG0009	L-threonylcarbamoyladenylate synthase
BOC50_RS15715	COG1994	Peptidase M50
BOC50_RS15720	COG0180	Tryptophanyl-tRNA synthetase
BOC50_RS15730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BOC50_RS15735	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BOC50_RS15740	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BOC50_RS15755	COG2850	peptidyl-arginine hydroxylation
BOC50_RS15800	COG0483	inositol monophosphate 1-phosphatase activity
BOC50_RS15815	COG1045	serine acetyltransferase
BOC50_RS15825	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BOC50_RS15835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BOC50_RS15860	COG0037	tRNA processing
BOC50_RS15870	COG0527	aspartate kinase activity
BOC50_RS15930	COG2895	sulfate adenylyltransferase (ATP) activity
BOC50_RS15930	COG0529	Catalyzes the synthesis of activated sulfate
BOC50_RS15960	COG2175	clavaminate synthase activity
BOC50_RS15980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BOC50_RS15985	COG3958	Transketolase
BOC50_RS16000	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BOC50_RS16020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BOC50_RS16040	COG0024	Methionine aminopeptidase
BOC50_RS16060	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BOC50_RS16075	COG0243	molybdopterin cofactor binding
BOC50_RS16100	COG4166	transmembrane transport
BOC50_RS16105	COG4174	ABC transporter (Permease)
BOC50_RS16110	COG4239	(ABC) transporter, permease
BOC50_RS16115	COG4172	Belongs to the ABC transporter superfamily
BOC50_RS16125	COG0791	NLP P60 protein
BOC50_RS16130	COG1752	Esterase of the alpha-beta hydrolase superfamily
BOC50_RS16195	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BOC50_RS16205	COG0583	DNA-binding transcription factor activity
BOC50_RS16215	COG2224	Isocitrate lyase
BOC50_RS16220	COG0513	Belongs to the DEAD box helicase family
BOC50_RS16230	COG1214	PFAM Peptidase M22, glycoprotease
BOC50_RS16245	COG1573	uracil-dna glycosylase
BOC50_RS16260	COG0351	phosphomethylpyrimidine kinase
BOC50_RS16265	COG0477	Major facilitator Superfamily
BOC50_RS16285	COG0488	(ABC) transporter
BOC50_RS16290	COG0386	Belongs to the glutathione peroxidase family
BOC50_RS16305	COG2890	protein-(glutamine-N5) methyltransferase activity
BOC50_RS16315	COG1393	Belongs to the ArsC family
BOC50_RS16360	COG0242	peptide deformylase activity
BOC50_RS16375	COG0024	Methionine aminopeptidase
BOC50_RS16405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BOC50_RS16420	COG0750	zinc metalloprotease
BOC50_RS16450	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BOC50_RS16460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BOC50_RS16510	COG0330	HflC and HflK could
BOC50_RS16520	COG2867	negative regulation of translational initiation
BOC50_RS16530	COG0697	spore germination
BOC50_RS16625	COG4962	Type ii secretion system protein e
BOC50_RS16645	COG2814	Major facilitator Superfamily
BOC50_RS16685	COG1619	proteins homologs of microcin C7 resistance protein MccF
BOC50_RS16695	COG1953	Uracil, thiamine, allantoin
BOC50_RS16710	COG3648	Uricase
BOC50_RS16710	COG3195	allantoin biosynthetic process
BOC50_RS16715	COG4266	Belongs to the allantoicase family
BOC50_RS16730	COG2351	hydroxyisourate hydrolase activity
BOC50_RS16745	COG0583	DNA-binding transcription factor activity
BOC50_RS16755	COG3360	Dodecin
BOC50_RS16835	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BOC50_RS16850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BOC50_RS16995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BOC50_RS17005	COG1846	Transcriptional regulator
BOC50_RS17010	COG1929	Belongs to the glycerate kinase type-1 family
BOC50_RS17035	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BOC50_RS17115	COG4181	ATPase activity
BOC50_RS17135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOC50_RS17145	COG0047	phosphoribosylformylglycinamidine synthase activity
BOC50_RS17145	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BOC50_RS17155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BOC50_RS17180	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS17190	COG1250	3-hydroxyacyl-CoA dehydrogenase
BOC50_RS17190	COG1024	Enoyl-CoA hydratase
BOC50_RS17195	COG1335	isochorismatase
BOC50_RS17200	COG0183	Belongs to the thiolase family
BOC50_RS17235	COG2130	NADP-dependent
BOC50_RS17240	COG0657	acetylesterase activity
BOC50_RS17255	COG0354	folic acid binding
BOC50_RS17260	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BOC50_RS17275	COG1247	-acetyltransferase
BOC50_RS17280	COG0084	hydrolase, TatD family'
BOC50_RS17310	COG0438	transferase activity, transferring glycosyl groups
BOC50_RS17340	COG0252	asparaginase activity
BOC50_RS17350	COG1652	LysM domain
BOC50_RS17360	COG2084	Dehydrogenase
BOC50_RS17365	COG3622	Belongs to the hyi family
BOC50_RS17370	COG3960	tartronate-semialdehyde synthase activity
BOC50_RS17375	COG0583	DNA-binding transcription factor activity
BOC50_RS17390	COG1595	DNA-templated transcription, initiation
BOC50_RS17435	COG0306	phosphate transporter
BOC50_RS17445	COG0791	NLP P60 protein
BOC50_RS17450	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BOC50_RS17460	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BOC50_RS17465	COG0726	polysaccharide deacetylase
BOC50_RS17470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BOC50_RS17470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BOC50_RS17480	COG0463	Glycosyl transferase, family 2
BOC50_RS17485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BOC50_RS17490	COG2076	Multidrug Resistance protein
BOC50_RS17495	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BOC50_RS17505	COG0436	Aminotransferase
BOC50_RS17535	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BOC50_RS17540	COG0314	molybdopterin synthase activity
BOC50_RS17545	COG2346	COG2346, Truncated hemoglobins
BOC50_RS17550	COG1959	2 iron, 2 sulfur cluster binding
BOC50_RS17555	COG0542	response to heat
BOC50_RS17585	COG0534	Mate efflux family protein
BOC50_RS17605	COG3228	Belongs to the MtfA family
BOC50_RS17610	COG0477	Major facilitator Superfamily
BOC50_RS17615	COG0789	Transcriptional regulator
BOC50_RS17620	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BOC50_RS17640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BOC50_RS17655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOC50_RS17700	COG0670	Belongs to the BI1 family
BOC50_RS17735	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BOC50_RS17750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BOC50_RS17755	COG0330	HflC and HflK could
BOC50_RS17760	COG0330	HflC and HflK could
BOC50_RS17780	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BOC50_RS17805	COG2183	response to ionizing radiation
BOC50_RS17820	COG1199	ATP-dependent helicase activity
BOC50_RS17830	COG0564	pseudouridine synthase activity
BOC50_RS17835	COG1496	oxidoreductase activity
BOC50_RS17840	COG3243	poly(R)-hydroxyalkanoic acid synthase
BOC50_RS17845	COG0183	Belongs to the thiolase family
BOC50_RS17850	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS17875	COG0183	Belongs to the thiolase family
BOC50_RS17885	COG0626	cystathionine gamma-synthase activity
BOC50_RS17890	COG0560	Phosphoserine phosphatase
BOC50_RS17910	COG0390	transport system, permease component
BOC50_RS17915	COG1122	ATPase activity
BOC50_RS17920	COG2982	Protein involved in outer membrane biogenesis
BOC50_RS17930	COG0488	(ABC) transporter
BOC50_RS17950	COG2070	2-Nitropropane dioxygenase
BOC50_RS17955	COG3047	cAMP biosynthetic process
BOC50_RS17970	COG1914	H( )-stimulated, divalent metal cation uptake system
BOC50_RS17975	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BOC50_RS17980	COG3842	ATPase activity
BOC50_RS17985	COG1176	ABC-type spermidine putrescine transport system, permease component I
BOC50_RS17990	COG1177	transmembrane transport
BOC50_RS17995	COG0730	response to heat
BOC50_RS17995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BOC50_RS18020	COG3655	Transcriptional regulator
BOC50_RS18045	COG1538	Outer membrane efflux protein
BOC50_RS18050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOC50_RS18065	COG0038	chloride channel
BOC50_RS18070	COG2855	membrane
BOC50_RS18090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BOC50_RS18110	COG1609	Transcriptional regulator
BOC50_RS18195	COG0598	Magnesium transport protein CorA
BOC50_RS18240	COG1196	nuclear chromosome segregation
BOC50_RS18240	COG3264	Mechanosensitive ion channel
BOC50_RS18270	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BOC50_RS18285	COG4263	nitrous-oxide reductase activity
BOC50_RS18310	COG0840	transmembrane signaling receptor activity
BOC50_RS18320	COG2376	Dihydroxyacetone kinase
BOC50_RS18340	COG0475	glutathione-regulated potassium exporter activity
BOC50_RS18425	COG3121	Chaperone
BOC50_RS18430	COG3188	usher protein
BOC50_RS18485	COG2197	response regulator
BOC50_RS18545	COG2916	Histone family protein nucleoid-structuring protein H-NS
BOC50_RS18575	COG2274	protein secretion by the type I secretion system
BOC50_RS18580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOC50_RS18590	COG0457	Tetratricopeptide repeat
BOC50_RS18590	COG0859	PFAM glycosyl transferase family 9
BOC50_RS18595	COG0529	Catalyzes the synthesis of activated sulfate
BOC50_RS18600	COG0745	RESPONSE REGULATOR receiver
BOC50_RS18630	COG1595	DNA-templated transcription, initiation
BOC50_RS18635	COG4944	Protein of unknown function (DUF1109)
BOC50_RS18655	COG3220	belongs to the UPF0276 family
BOC50_RS18680	COG2192	nodulation
BOC50_RS18705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BOC50_RS18725	COG0165	Argininosuccinate lyase
BOC50_RS18730	COG0137	argininosuccinate synthase activity
BOC50_RS18745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BOC50_RS18755	COG3251	PFAM MbtH domain protein
BOC50_RS18775	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS18790	COG0697	spore germination
BOC50_RS18795	COG0835	chemotaxis
BOC50_RS18820	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS18825	COG0477	Major facilitator Superfamily
BOC50_RS18845	COG1732	Glycine betaine
BOC50_RS18850	COG1174	glycine betaine transport
BOC50_RS18855	COG1125	glycine betaine transport
BOC50_RS18860	COG1174	glycine betaine transport
BOC50_RS18880	COG2235	arginine
BOC50_RS18885	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BOC50_RS18910	COG0583	DNA-binding transcription factor activity
BOC50_RS18915	COG0625	glutathione transferase activity
BOC50_RS18935	COG1846	Transcriptional regulator
BOC50_RS18940	COG2807	transmembrane transport
BOC50_RS18945	COG1649	PFAM Uncharacterised BCR, COG1649
BOC50_RS18965	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BOC50_RS18975	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BOC50_RS18995	COG3979	chitinase
BOC50_RS19015	COG0400	carboxylic ester hydrolase activity
BOC50_RS19050	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BOC50_RS19075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BOC50_RS19080	COG4774	siderophore transport
BOC50_RS19085	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BOC50_RS19135	COG1120	ATPase activity
BOC50_RS19170	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS19175	COG1070	Carbohydrate kinase
BOC50_RS19180	COG1063	alcohol dehydrogenase
BOC50_RS19190	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOC50_RS19200	COG1879	ABC-type sugar transport system periplasmic component
BOC50_RS19230	COG2375	cellular response to nickel ion
BOC50_RS19230	COG1132	(ABC) transporter
BOC50_RS19240	COG3121	Chaperone
BOC50_RS19250	COG3539	Fimbrial protein
BOC50_RS19275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOC50_RS19285	COG1309	transcriptional regulator
BOC50_RS19290	COG0739	heme binding
BOC50_RS19295	COG0765	amino acid transport
BOC50_RS19300	COG4597	amino acid ABC transporter
BOC50_RS19315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOC50_RS19360	COG4964	Belongs to the GSP D family
BOC50_RS19385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BOC50_RS19390	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BOC50_RS19405	COG0477	Major facilitator Superfamily
BOC50_RS19415	COG2719	SpoVR family
BOC50_RS19420	COG2718	Belongs to the UPF0229 family
BOC50_RS19425	COG2766	serine protein kinase
BOC50_RS19435	COG0840	transmembrane signaling receptor activity
BOC50_RS19440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BOC50_RS19445	COG1609	Transcriptional regulator
BOC50_RS19450	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOC50_RS19455	COG1129	ABC transporter
BOC50_RS19460	COG1879	ABC-type sugar transport system periplasmic component
BOC50_RS19465	COG0583	DNA-binding transcription factor activity
BOC50_RS19470	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BOC50_RS19475	COG4208	sulfate ABC transporter
BOC50_RS19480	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BOC50_RS19485	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BOC50_RS19535	COG0701	Predicted permease
BOC50_RS19540	COG0667	Aldo Keto reductase
BOC50_RS19570	COG1301	dicarboxylic acid transport
BOC50_RS19610	COG1116	anion transmembrane transporter activity
BOC50_RS19615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BOC50_RS19680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOC50_RS19685	COG0765	amino acid transport
BOC50_RS19690	COG0673	inositol 2-dehydrogenase activity
BOC50_RS19695	COG1802	Transcriptional regulator
BOC50_RS19705	COG3023	N-Acetylmuramoyl-L-alanine amidase
BOC50_RS19715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BOC50_RS19720	COG0557	exoribonuclease II activity
BOC50_RS19735	COG0840	transmembrane signaling receptor activity
BOC50_RS19765	COG0519	Catalyzes the synthesis of GMP from XMP
BOC50_RS19775	COG2814	Major facilitator Superfamily
BOC50_RS19785	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS19855	COG4964	Belongs to the GSP D family
BOC50_RS19920	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BOC50_RS19925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BOC50_RS19930	COG0508	dehydrogenase complex catalyzes the overall conversion of
BOC50_RS19935	COG0567	Dehydrogenase, E1 component
BOC50_RS19940	COG1217	gtp-binding protein TYPA
BOC50_RS19950	COG1846	Transcriptional regulator
BOC50_RS19960	COG1566	PFAM secretion protein HlyD family protein
BOC50_RS19965	COG2814	Major facilitator Superfamily
BOC50_RS19975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BOC50_RS19990	COG0195	Participates in both transcription termination and antitermination
BOC50_RS19990	COG2251	uridine kinase activity
BOC50_RS20000	COG1187	pseudouridine synthase activity
BOC50_RS20005	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BOC50_RS20010	COG0583	DNA-binding transcription factor activity
BOC50_RS20070	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BOC50_RS20095	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BOC50_RS20095	COG2755	lipolytic protein G-D-S-L family
BOC50_RS20110	COG0776	regulation of translation
BOC50_RS20135	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BOC50_RS20150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BOC50_RS20155	COG0251	oxidation-reduction process
BOC50_RS20160	COG2267	carboxylic ester hydrolase activity
BOC50_RS20170	COG0583	DNA-binding transcription factor activity
BOC50_RS20185	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS20235	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS20265	COG0477	Major facilitator Superfamily
BOC50_RS20290	COG1295	ribonuclease BN
BOC50_RS20295	COG0582	viral genome integration into host DNA
BOC50_RS20325	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BOC50_RS20325	COG2755	lipolytic protein G-D-S-L family
BOC50_RS20340	COG3299	homolog of phage Mu protein gp47
BOC50_RS20380	COG4386	tail sheath protein
BOC50_RS20655	COG0277	FAD linked oxidase domain protein
BOC50_RS20670	COG0583	DNA-binding transcription factor activity
BOC50_RS20700	COG0840	transmembrane signaling receptor activity
BOC50_RS20705	COG2223	nitrite transmembrane transporter activity
BOC50_RS20710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BOC50_RS20715	COG0210	DNA helicase
BOC50_RS20720	COG0525	valine-tRNA ligase activity
BOC50_RS20725	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BOC50_RS20735	COG5002	protein histidine kinase activity
BOC50_RS20745	COG0745	RESPONSE REGULATOR receiver
BOC50_RS20755	COG0425	Belongs to the sulfur carrier protein TusA family
BOC50_RS20765	COG0673	inositol 2-dehydrogenase activity
BOC50_RS20770	COG0673	inositol 2-dehydrogenase activity
BOC50_RS20785	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOC50_RS20800	COG3962	Belongs to the TPP enzyme family
BOC50_RS20810	COG3718	enzyme involved in inositol metabolism
BOC50_RS20820	COG0411	ABC transporter
BOC50_RS20830	COG0824	Thioesterase
BOC50_RS20855	COG2816	NAD+ diphosphatase activity
BOC50_RS20870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BOC50_RS20880	COG0477	Major facilitator Superfamily
BOC50_RS20895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOC50_RS20905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BOC50_RS20915	COG1051	belongs to the nudix hydrolase family
BOC50_RS20945	COG1858	cytochrome C peroxidase
BOC50_RS20950	COG3511	phospholipase C
BOC50_RS20965	COG1566	PFAM secretion protein HlyD family protein
BOC50_RS20975	COG2814	Major facilitator Superfamily
BOC50_RS20980	COG1538	Outer membrane efflux protein
BOC50_RS20990	COG2197	response regulator
BOC50_RS21045	COG0583	DNA-binding transcription factor activity
BOC50_RS21055	COG2814	Major facilitator Superfamily
BOC50_RS21100	COG1914	H( )-stimulated, divalent metal cation uptake system
BOC50_RS21290	COG0859	PFAM glycosyl transferase family 9
BOC50_RS21290	COG0457	Tetratricopeptide repeat
BOC50_RS21340	COG0745	RESPONSE REGULATOR receiver
BOC50_RS21345	COG0583	DNA-binding transcription factor activity
BOC50_RS21400	COG0366	Alpha amylase catalytic
BOC50_RS21405	COG0366	Alpha amylase catalytic
BOC50_RS21410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BOC50_RS21455	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BOC50_RS21525	COG4942	peptidase
BOC50_RS21535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BOC50_RS21550	COG0534	Mate efflux family protein
BOC50_RS21630	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BOC50_RS21645	COG0745	RESPONSE REGULATOR receiver
BOC50_RS21660	COG0581	inorganic phosphate transmembrane transporter activity
BOC50_RS21665	COG0573	inorganic phosphate transmembrane transporter activity
BOC50_RS21670	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BOC50_RS21685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BOC50_RS21690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BOC50_RS21700	COG1534	Rna-binding protein
BOC50_RS21710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BOC50_RS21715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BOC50_RS21725	COG0505	Belongs to the CarA family
BOC50_RS21755	COG1388	LysM domain
BOC50_RS21755	COG0741	lytic transglycosylase activity
BOC50_RS21760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BOC50_RS21765	COG2226	methyltransferase
BOC50_RS21770	COG0328	RNA-DNA hybrid ribonuclease activity
BOC50_RS21775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BOC50_RS21790	COG0477	Major facilitator Superfamily
BOC50_RS21820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BOC50_RS21830	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BOC50_RS21850	COG3052	prosthetic group binding
BOC50_RS21875	COG0583	DNA-binding transcription factor activity
BOC50_RS21885	COG1250	3-hydroxyacyl-CoA dehydrogenase
BOC50_RS21890	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BOC50_RS21940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BOC50_RS21980	COG0583	DNA-binding transcription factor activity
BOC50_RS22010	COG1522	sequence-specific DNA binding
BOC50_RS22080	COG1609	Transcriptional regulator
BOC50_RS22085	COG1840	ABC-type Fe3 transport system, periplasmic component
BOC50_RS22090	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BOC50_RS22105	COG1177	transmembrane transport
BOC50_RS22115	COG3842	ATPase activity
BOC50_RS22125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BOC50_RS22150	COG2814	Major facilitator Superfamily
BOC50_RS22155	COG0697	spore germination
BOC50_RS22170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BOC50_RS22175	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BOC50_RS22220	COG2200	EAL domain
BOC50_RS22230	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BOC50_RS22235	COG1074	ATP-dependent DNA helicase activity
BOC50_RS22240	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BOC50_RS22255	COG1289	transmembrane transporter activity
BOC50_RS22280	COG1840	ABC-type Fe3 transport system, periplasmic component
BOC50_RS22285	COG1176	ABC-type spermidine putrescine transport system, permease component I
BOC50_RS22290	COG3842	ATPase activity
BOC50_RS22295	COG1522	sequence-specific DNA binding
BOC50_RS22315	COG1959	2 iron, 2 sulfur cluster binding
BOC50_RS22350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOC50_RS22355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOC50_RS22395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BOC50_RS22410	COG2010	Cytochrome c
BOC50_RS22410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BOC50_RS22415	COG2863	cytochrome
BOC50_RS22450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BOC50_RS22470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BOC50_RS22490	COG0006	proline dipeptidase activity
BOC50_RS22560	COG2866	Carboxypeptidase
BOC50_RS22575	COG0436	Aminotransferase
BOC50_RS22585	COG1024	Enoyl-CoA hydratase
BOC50_RS22590	COG0588	phosphoglycerate mutase activity
BOC50_RS22600	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS22620	COG1012	belongs to the aldehyde dehydrogenase family
BOC50_RS22620	COG2030	dehydratase
BOC50_RS22625	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS22630	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS22650	COG1007	ATP synthesis coupled electron transport
BOC50_RS22685	COG1034	ATP synthesis coupled electron transport
BOC50_RS22685	COG1034	ATP synthesis coupled electron transport
BOC50_RS22695	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BOC50_RS22730	COG0149	triose-phosphate isomerase activity
BOC50_RS22735	COG3321	synthase
BOC50_RS22735	COG4221	oxidoreductase activity
BOC50_RS22735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOC50_RS22735	COG0604	alcohol dehydrogenase
BOC50_RS22755	COG0683	leucine binding
BOC50_RS22770	COG0288	reversible hydration of carbon dioxide
BOC50_RS22775	COG0659	secondary active sulfate transmembrane transporter activity
BOC50_RS22790	COG1183	phosphatidylcholine synthase activity
BOC50_RS22810	COG0028	Belongs to the TPP enzyme family
BOC50_RS22845	COG0438	transferase activity, transferring glycosyl groups
BOC50_RS22865	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS22875	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BOC50_RS22885	COG0154	amidase activity
BOC50_RS22895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BOC50_RS22930	COG0745	RESPONSE REGULATOR receiver
BOC50_RS22935	COG2205	protein histidine kinase activity
BOC50_RS22950	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BOC50_RS22955	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BOC50_RS22985	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS23005	COG0151	Belongs to the GarS family
BOC50_RS23020	COG0799	negative regulation of ribosome biogenesis
BOC50_RS23045	COG2233	PERMEase
BOC50_RS23100	COG1595	DNA-templated transcription, initiation
BOC50_RS23110	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BOC50_RS23155	COG0859	PFAM glycosyl transferase family 9
BOC50_RS23160	COG0438	transferase activity, transferring glycosyl groups
BOC50_RS23200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BOC50_RS23210	COG0513	Belongs to the DEAD box helicase family
BOC50_RS23245	COG1674	ftsk spoiiie
BOC50_RS23250	COG2706	6-phosphogluconolactonase activity
BOC50_RS23260	COG3387	PFAM Glycoside hydrolase 15-related
BOC50_RS23270	COG1309	transcriptional regulator
BOC50_RS23275	COG2878	Part of a membrane complex involved in electron transport
BOC50_RS23280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BOC50_RS23315	COG3135	benzoate transporter
BOC50_RS23330	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BOC50_RS23345	COG4106	trans-aconitate 2-methyltransferase activity
BOC50_RS23370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BOC50_RS23380	COG0697	spore germination
BOC50_RS23385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BOC50_RS23430	COG0477	Major facilitator Superfamily
BOC50_RS23440	COG0583	DNA-binding transcription factor activity
BOC50_RS23450	COG0583	DNA-binding transcription factor activity
BOC50_RS23480	COG0488	(ABC) transporter
BOC50_RS23490	COG1773	rubredoxin
BOC50_RS23855	COG3436	PFAM IS66 Orf2 family protein
BOC50_RS23860	COG4372	Transposase
BOC50_RS23865	COG3012	SEC-C Motif Domain Protein
BOC50_RS23975	COG1881	PFAM PEBP family protein
BOC50_RS23980	COG2814	Major facilitator Superfamily
BOC50_RS24000	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BOC50_RS24030	COG1116	anion transmembrane transporter activity
BOC50_RS24035	COG1176	ABC-type spermidine putrescine transport system, permease component I
BOC50_RS24070	COG1741	Belongs to the pirin family
BOC50_RS24085	COG4215	(ABC) transporter
BOC50_RS24105	COG0347	Belongs to the P(II) protein family
BOC50_RS24125	COG1472	Belongs to the glycosyl hydrolase 3 family
BOC50_RS24135	COG2827	Endonuclease containing a URI domain
BOC50_RS24140	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BOC50_RS24155	COG2271	Major facilitator Superfamily
BOC50_RS24195	COG2226	methyltransferase
BOC50_RS24235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BOC50_RS24260	COG0489	protein tyrosine kinase activity
BOC50_RS24270	COG3047	cAMP biosynthetic process
BOC50_RS24270	COG2885	chlorophyll binding
BOC50_RS24300	COG2911	Protein conserved in bacteria
BOC50_RS24305	COG0729	surface antigen
BOC50_RS24315	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BOC50_RS24335	COG0489	protein tyrosine kinase activity
BOC50_RS24340	COG2259	Doxx family
BOC50_RS24345	COG1492	cobalamin metabolic process
BOC50_RS24355	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BOC50_RS24365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BOC50_RS24385	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BOC50_RS24390	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BOC50_RS24400	COG4206	TonB-dependent receptor
BOC50_RS24440	COG0583	DNA-binding transcription factor activity
BOC50_RS24460	COG4654	Cytochrome c, class I
BOC50_RS24480	COG0795	lipopolysaccharide-transporting ATPase activity
BOC50_RS24495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BOC50_RS24495	COG1648	precorrin-2 dehydrogenase activity
BOC50_RS24500	COG2895	sulfate adenylyltransferase (ATP) activity
BOC50_RS24510	COG0175	sulfate reduction
BOC50_RS24525	COG0583	DNA-binding transcription factor activity
BOC50_RS24545	COG0582	viral genome integration into host DNA
BOC50_RS24620	COG1396	sequence-specific DNA binding
BOC50_RS24630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BOC50_RS24635	COG2258	MOSC domain
BOC50_RS24640	COG2267	carboxylic ester hydrolase activity
BOC50_RS24650	COG0583	DNA-binding transcription factor activity
BOC50_RS24660	COG1187	pseudouridine synthase activity
BOC50_RS24675	COG0543	2 iron, 2 sulfur cluster binding
BOC50_RS24675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BOC50_RS24680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BOC50_RS24685	COG0456	acetyltransferase
BOC50_RS24725	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BOC50_RS24730	COG1047	Peptidyl-prolyl cis-trans
BOC50_RS24750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BOC50_RS24775	COG1511	domain protein
BOC50_RS24775	COG3264	Mechanosensitive ion channel
BOC50_RS24780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BOC50_RS24780	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BOC50_RS24785	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BOC50_RS24790	COG0196	riboflavin kinase activity
BOC50_RS24795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BOC50_RS24825	COG1113	amino acid transport
BOC50_RS24830	COG0542	response to heat
BOC50_RS24840	COG1278	Cold shock
BOC50_RS24875	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BOC50_RS24915	COG0656	L-ascorbic acid biosynthetic process
BOC50_RS24920	COG2188	Transcriptional regulator
BOC50_RS24940	COG2814	Major facilitator Superfamily
BOC50_RS25000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BOC50_RS25005	COG1570	exodeoxyribonuclease VII activity
BOC50_RS25015	COG1663	tetraacyldisaccharide 4'-kinase activity
BOC50_RS25055	COG0728	peptidoglycan biosynthetic process
BOC50_RS25075	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BOC50_RS25080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BOC50_RS25095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BOC50_RS25100	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS25105	COG4974	Belongs to the 'phage' integrase family
BOC50_RS25115	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BOC50_RS25120	COG0802	atpase or kinase
BOC50_RS25125	COG0860	N-Acetylmuramoyl-L-alanine amidase
BOC50_RS25140	COG1741	Belongs to the pirin family
BOC50_RS25145	COG3118	belongs to the thioredoxin family
BOC50_RS25155	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BOC50_RS25165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BOC50_RS25180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BOC50_RS25190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BOC50_RS25195	COG1522	sequence-specific DNA binding
BOC50_RS25215	COG2271	Major facilitator Superfamily
BOC50_RS25225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BOC50_RS25230	COG1012	belongs to the aldehyde dehydrogenase family
BOC50_RS25240	COG0583	DNA-binding transcription factor activity
BOC50_RS25245	COG0246	Mannitol dehydrogenase
BOC50_RS25250	COG1070	Carbohydrate kinase
BOC50_RS25255	COG2390	Transcriptional regulator
BOC50_RS25270	COG0583	DNA-binding transcription factor activity
BOC50_RS25285	COG3842	ATPase activity
BOC50_RS25290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BOC50_RS25300	COG1175	transmembrane transport
BOC50_RS25315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BOC50_RS25325	COG0735	belongs to the Fur family
BOC50_RS25335	COG1121	(ABC) transporter
BOC50_RS25340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BOC50_RS25345	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BOC50_RS25360	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BOC50_RS25365	COG2233	PERMEase
BOC50_RS25380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOC50_RS25385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOC50_RS25415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BOC50_RS25460	COG0009	L-threonylcarbamoyladenylate synthase
BOC50_RS25465	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BOC50_RS25470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BOC50_RS25475	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BOC50_RS25485	COG0469	pyruvate kinase activity
BOC50_RS25495	COG0126	phosphoglycerate kinase activity
BOC50_RS25520	COG0859	PFAM glycosyl transferase family 9
BOC50_RS25530	COG0429	hydrolase of the alpha beta-hydrolase fold
BOC50_RS25540	COG4783	chaperone-mediated protein folding
BOC50_RS25575	COG3307	-O-antigen
BOC50_RS25580	COG4969	Belongs to the N-Me-Phe pilin family
BOC50_RS25585	COG0861	Integral membrane protein TerC family
BOC50_RS25590	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BOC50_RS25605	COG2137	regulation of response to DNA damage stimulus
BOC50_RS25610	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BOC50_RS25645	COG3620	sequence-specific DNA binding
BOC50_RS25845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BOC50_RS25885	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BOC50_RS25895	COG3586	endonuclease activity
BOC50_RS25935	COG0784	Response regulator, receiver
BOC50_RS25935	COG5002	protein histidine kinase activity
BOC50_RS25980	COG0028	Belongs to the TPP enzyme family
BOC50_RS25985	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BOC50_RS25990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BOC50_RS26075	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BOC50_RS26080	COG0583	DNA-binding transcription factor activity
BOC50_RS26085	COG1301	dicarboxylic acid transport
BOC50_RS26100	COG0840	transmembrane signaling receptor activity
BOC50_RS26145	COG4948	Mandelate Racemase Muconate Lactonizing
BOC50_RS26175	COG0513	Belongs to the DEAD box helicase family
BOC50_RS26220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BOC50_RS26225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BOC50_RS26240	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BOC50_RS26245	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BOC50_RS26250	COG0367	asparagine synthase
BOC50_RS26265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BOC50_RS26275	COG1396	sequence-specific DNA binding
BOC50_RS26280	COG2814	Major facilitator Superfamily
BOC50_RS26285	COG0583	DNA-binding transcription factor activity
BOC50_RS26300	COG1702	phosphate starvation-inducible protein PhoH
BOC50_RS26315	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BOC50_RS26325	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BOC50_RS26330	COG0752	glycyl-tRNA synthetase alpha subunit
BOC50_RS26335	COG0751	glycine-tRNA ligase activity
BOC50_RS26340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BOC50_RS26345	COG0204	Acyl-transferase
BOC50_RS26375	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BOC50_RS26395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BOC50_RS26405	COG5265	(ABC) transporter
BOC50_RS26425	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BOC50_RS26430	COG1024	Enoyl-CoA hydratase
BOC50_RS26435	COG0183	Belongs to the thiolase family
BOC50_RS26440	COG1024	Enoyl-CoA hydratase
BOC50_RS26440	COG1250	3-hydroxyacyl-CoA dehydrogenase
BOC50_RS26445	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS26460	COG0494	nUDIX hydrolase
BOC50_RS26535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BOC50_RS26545	COG0251	oxidation-reduction process
BOC50_RS26555	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BOC50_RS26580	COG0477	Major facilitator Superfamily
BOC50_RS26625	COG1596	polysaccharide export
BOC50_RS26630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BOC50_RS26650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BOC50_RS26660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BOC50_RS26680	COG2204	response regulator
BOC50_RS26725	COG5002	protein histidine kinase activity
BOC50_RS26725	COG5001	Diguanylate cyclase
BOC50_RS26740	COG0235	Class ii aldolase
BOC50_RS26855	COG0629	single-stranded DNA binding
BOC50_RS26860	COG2814	Major facilitator Superfamily
BOC50_RS26895	COG1280	lysine exporter protein (LysE YggA)
BOC50_RS26920	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BOC50_RS26935	COG1137	ATPase activity
BOC50_RS26940	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BOC50_RS26950	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BOC50_RS26975	COG1194	a g-specific adenine glycosylase
BOC50_RS26990	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BOC50_RS27005	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BOC50_RS27025	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BOC50_RS27040	COG0742	ribosomal rna small subunit methyltransferase
BOC50_RS27050	COG0625	glutathione transferase activity
BOC50_RS27060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BOC50_RS27070	COG0243	molybdopterin cofactor binding
BOC50_RS27075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BOC50_RS27090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BOC50_RS27100	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BOC50_RS27110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BOC50_RS27125	COG1294	oxidase, subunit
BOC50_RS27155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BOC50_RS27155	COG2190	(PTS) system
BOC50_RS27155	COG1263	PTS System
BOC50_RS27160	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOC50_RS27160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BOC50_RS27165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BOC50_RS27170	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BOC50_RS27175	COG2188	Transcriptional regulator
BOC50_RS27185	COG0583	DNA-binding transcription factor activity
BOC50_RS27230	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS27240	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS27250	COG2226	methyltransferase
BOC50_RS27260	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BOC50_RS27285	COG2814	Major facilitator Superfamily
BOC50_RS27295	COG0587	DNA-directed DNA polymerase activity
BOC50_RS27310	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BOC50_RS27340	COG0840	transmembrane signaling receptor activity
BOC50_RS27350	COG1999	signal sequence binding
BOC50_RS27360	COG1612	heme a metabolic process
BOC50_RS27390	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BOC50_RS27400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BOC50_RS27415	COG2226	methyltransferase
BOC50_RS27420	COG1040	competence protein
BOC50_RS27435	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BOC50_RS27455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BOC50_RS27465	COG0793	Belongs to the peptidase S41A family
BOC50_RS27470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BOC50_RS27480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BOC50_RS27485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOC50_RS27495	COG0189	ligase activity
BOC50_RS27505	COG0004	ammonium transporteR
BOC50_RS27515	COG2960	long-chain fatty acid transporting porin activity
BOC50_RS27555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BOC50_RS27565	COG4191	Histidine kinase
BOC50_RS27575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BOC50_RS27585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOC50_RS27590	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS27595	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS27600	COG1024	Enoyl-CoA hydratase
BOC50_RS27600	COG1250	3-hydroxyacyl-CoA dehydrogenase
BOC50_RS27605	COG0583	DNA-binding transcription factor activity
BOC50_RS27620	COG0405	Gamma-glutamyltransferase
BOC50_RS27645	COG0583	DNA-binding transcription factor activity
BOC50_RS27650	COG2921	Belongs to the UPF0250 family
BOC50_RS27660	COG1686	Belongs to the peptidase S11 family
BOC50_RS27695	COG1127	ABC transporter
BOC50_RS27700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BOC50_RS27705	COG0737	Belongs to the 5'-nucleotidase family
BOC50_RS27720	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BOC50_RS27730	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BOC50_RS27755	COG1024	Enoyl-CoA hydratase
BOC50_RS27815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BOC50_RS27820	COG4221	oxidoreductase activity
BOC50_RS27825	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS27845	COG0747	negative chemotaxis
BOC50_RS27850	COG0488	(ABC) transporter
BOC50_RS27870	COG0288	reversible hydration of carbon dioxide
BOC50_RS27875	COG0183	Belongs to the thiolase family
BOC50_RS27885	COG3012	SEC-C Motif Domain Protein
BOC50_RS27905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BOC50_RS27935	COG1785	Belongs to the alkaline phosphatase family
BOC50_RS27945	COG2200	EAL domain
BOC50_RS27945	COG2199	diguanylate cyclase activity
BOC50_RS27950	COG0025	NhaP-type Na H and K H
BOC50_RS28025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BOC50_RS28045	COG1999	signal sequence binding
BOC50_RS28080	COG3511	phospholipase C
BOC50_RS28100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BOC50_RS28130	COG0596	Alpha beta hydrolase
BOC50_RS28145	COG0583	DNA-binding transcription factor activity
BOC50_RS28150	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS28180	COG1609	Transcriptional regulator
BOC50_RS28235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BOC50_RS28240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BOC50_RS28255	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOC50_RS28260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOC50_RS28280	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BOC50_RS28285	COG1704	LemA family
BOC50_RS28410	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS28425	COG2824	Alkylphosphonate utilization operon protein PhnA
BOC50_RS28455	COG0583	DNA-binding transcription factor activity
BOC50_RS28460	COG2233	PERMEase
BOC50_RS28470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BOC50_RS28480	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BOC50_RS28490	COG1706	bacterial-type flagellum-dependent cell motility
BOC50_RS28495	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BOC50_RS28510	COG1749	Flagellar hook protein flgE
BOC50_RS28515	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BOC50_RS28520	COG1558	bacterial-type flagellum-dependent cell motility
BOC50_RS28525	COG1815	bacterial-type flagellum-dependent cell motility
BOC50_RS28535	COG2747	anti-sigma28 factor FlgM
BOC50_RS28580	COG0741	lytic transglycosylase activity
BOC50_RS28585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BOC50_RS28595	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BOC50_RS28600	COG1984	allophanate hydrolase subunit 2
BOC50_RS28630	COG4608	Belongs to the ABC transporter superfamily
BOC50_RS28635	COG0444	Belongs to the ABC transporter superfamily
BOC50_RS28640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOC50_RS28645	COG0601	transmembrane transport
BOC50_RS28650	COG0747	negative chemotaxis
BOC50_RS28670	COG0579	oxidoreductase
BOC50_RS28690	COG3568	Endonuclease Exonuclease Phosphatase
BOC50_RS28695	COG1280	lysine exporter protein (LysE YggA)
BOC50_RS28715	COG0531	amino acid
BOC50_RS28730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BOC50_RS28790	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS28805	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BOC50_RS28815	COG2814	Major facilitator Superfamily
BOC50_RS28835	COG0667	Aldo Keto reductase
BOC50_RS28865	COG1560	Kdo2-lipid A biosynthetic process
BOC50_RS28880	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BOC50_RS28890	COG0523	cobalamin synthesis protein
BOC50_RS28920	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BOC50_RS28945	COG1309	transcriptional regulator
BOC50_RS28960	COG2814	Major facilitator Superfamily
BOC50_RS28975	COG2207	Transcriptional regulator
BOC50_RS28980	COG1064	alcohol dehydrogenase
BOC50_RS28990	COG0708	Exodeoxyribonuclease III
BOC50_RS28995	COG2326	polyphosphate kinase activity
BOC50_RS29015	COG1077	Cell shape determining protein MreB Mrl
BOC50_RS29030	COG0768	penicillin binding
BOC50_RS29035	COG0772	Belongs to the SEDS family
BOC50_RS29065	COG0720	synthase
BOC50_RS29070	COG0602	queuosine metabolic process
BOC50_RS29090	COG2204	response regulator
BOC50_RS29095	COG5000	phosphorelay sensor kinase activity
BOC50_RS29130	COG0242	peptide deformylase activity
BOC50_RS29135	COG0758	DNA mediated transformation
BOC50_RS29150	COG0583	DNA-binding transcription factor activity
BOC50_RS29155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BOC50_RS29200	COG3436	PFAM IS66 Orf2 family protein
BOC50_RS29205	COG4372	Transposase
BOC50_RS29210	COG3012	SEC-C Motif Domain Protein
BOC50_RS29275	COG4695	Portal protein
BOC50_RS29295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BOC50_RS29310	COG0583	DNA-binding transcription factor activity
BOC50_RS29340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BOC50_RS29355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BOC50_RS29355	COG2169	Transcriptional regulator
BOC50_RS29385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BOC50_RS29480	COG3645	SOS response
BOC50_RS29485	COG0582	viral genome integration into host DNA
BOC50_RS29525	COG0592	DNA-directed DNA polymerase activity
BOC50_RS29550	COG0753	catalase activity
BOC50_RS29595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOC50_RS29600	COG1250	3-hydroxyacyl-CoA dehydrogenase
BOC50_RS29600	COG1024	Enoyl-CoA hydratase
BOC50_RS29605	COG0183	Belongs to the thiolase family
BOC50_RS29615	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS29650	COG1695	Transcriptional regulator
BOC50_RS29725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS29750	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS29765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BOC50_RS29775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BOC50_RS29785	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BOC50_RS29785	COG4106	trans-aconitate 2-methyltransferase activity
BOC50_RS29790	COG0789	Transcriptional regulator
BOC50_RS29800	COG1987	bacterial-type flagellum assembly
BOC50_RS29815	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BOC50_RS29835	COG1346	cytolysis
BOC50_RS29845	COG0583	DNA-binding transcription factor activity
BOC50_RS29850	COG2814	Major facilitator Superfamily
BOC50_RS29855	COG1846	Transcriptional regulator
BOC50_RS29900	COG2165	general secretion pathway protein
BOC50_RS29945	COG0523	cobalamin synthesis protein
BOC50_RS29990	COG0519	Catalyzes the synthesis of GMP from XMP
BOC50_RS29990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BOC50_RS29995	COG1902	pentaerythritol trinitrate reductase activity
BOC50_RS30015	COG0642	Histidine kinase
BOC50_RS30035	COG3186	Phenylalanine-4-hydroxylase
BOC50_RS30040	COG1522	sequence-specific DNA binding
BOC50_RS30055	COG0583	DNA-binding transcription factor activity
BOC50_RS30065	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BOC50_RS30095	COG0559	Belongs to the binding-protein-dependent transport system permease family
BOC50_RS30140	COG1192	Involved in chromosome partitioning
BOC50_RS30145	COG1475	DNA binding
BOC50_RS30150	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BOC50_RS30165	COG0356	it plays a direct role in the translocation of protons across the membrane
BOC50_RS30205	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS30220	COG1832	CoA-binding protein
BOC50_RS30240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BOC50_RS30260	COG0506	proline dehydrogenase activity
BOC50_RS30260	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BOC50_RS30260	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BOC50_RS30275	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS30295	COG0436	Aminotransferase
BOC50_RS30310	COG0277	FAD linked oxidase domain protein
BOC50_RS30320	COG0789	Transcriptional regulator
BOC50_RS30340	COG0668	transmembrane transport
BOC50_RS30360	COG0531	amino acid
BOC50_RS30365	COG4303	Ethanolamine ammonia lyase large subunit
BOC50_RS30370	COG4302	ethanolamine ammonia-lyase activity
BOC50_RS30380	COG1012	belongs to the aldehyde dehydrogenase family
BOC50_RS30410	COG1760	l-serine dehydratase
BOC50_RS30425	COG0509	glycine decarboxylation via glycine cleavage system
BOC50_RS30440	COG0673	inositol 2-dehydrogenase activity
BOC50_RS30460	COG0210	DNA helicase
BOC50_RS30465	COG3245	cytochrome
BOC50_RS30485	COG0582	viral genome integration into host DNA
BOC50_RS30530	COG3397	chitin binding
BOC50_RS30555	COG2267	carboxylic ester hydrolase activity
BOC50_RS30630	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS30645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BOC50_RS30690	COG0519	Catalyzes the synthesis of GMP from XMP
BOC50_RS30700	COG0561	phosphatase activity
BOC50_RS30705	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BOC50_RS30720	COG0438	transferase activity, transferring glycosyl groups
BOC50_RS30745	COG1360	Flagellar Motor Protein
BOC50_RS30750	COG2201	protein-glutamate methylesterase activity
BOC50_RS30770	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BOC50_RS30780	COG2201	protein-glutamate methylesterase activity
BOC50_RS30790	COG0745	RESPONSE REGULATOR receiver
BOC50_RS30795	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BOC50_RS30815	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BOC50_RS30820	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BOC50_RS30845	COG1950	PFAM Membrane protein of
BOC50_RS30850	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BOC50_RS30865	COG2070	2-Nitropropane dioxygenase
BOC50_RS30900	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BOC50_RS30905	COG1522	sequence-specific DNA binding
BOC50_RS30915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BOC50_RS30940	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BOC50_RS30945	COG2823	Periplasmic or secreted lipoprotein
BOC50_RS31040	COG5377	YqaJ viral recombinase family
BOC50_RS31055	COG1401	restriction endodeoxyribonuclease activity
BOC50_RS31070	COG2856	Zn peptidase
BOC50_RS31090	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BOC50_RS31110	COG0433	COG0433 Predicted ATPase
BOC50_RS31115	COG0582	viral genome integration into host DNA
BOC50_RS31125	COG3436	PFAM IS66 Orf2 family protein
BOC50_RS31130	COG4372	Transposase
BOC50_RS31135	COG3012	SEC-C Motif Domain Protein
BOC50_RS31170	COG1113	amino acid transport
BOC50_RS31215	COG2084	Dehydrogenase
BOC50_RS31220	COG1280	lysine exporter protein (LysE YggA)
BOC50_RS31225	COG2814	Major facilitator Superfamily
BOC50_RS31230	COG0583	DNA-binding transcription factor activity
BOC50_RS31235	COG3047	cAMP biosynthetic process
BOC50_RS31255	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BOC50_RS31270	COG1881	PFAM PEBP family protein
BOC50_RS31275	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BOC50_RS31285	COG0280	phosphate acetyltransferase
BOC50_RS31285	COG0281	malic enzyme
BOC50_RS31315	COG1522	sequence-specific DNA binding
BOC50_RS31335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BOC50_RS31340	COG2151	metal-sulfur cluster biosynthetic enzyme
BOC50_RS31345	COG3396	Phenylacetate-CoA oxygenase
BOC50_RS31350	COG3460	Phenylacetate-CoA oxygenase
BOC50_RS31355	COG3396	Phenylacetate-CoA oxygenase
BOC50_RS31445	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BOC50_RS31485	COG0514	ATP-dependent DNA helicase (RecQ)
BOC50_RS31620	COG0201	protein transport
BOC50_RS31665	COG4232	protein-disulfide reductase activity
BOC50_RS31685	COG1333	cytochrome c biogenesis protein
BOC50_RS31690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BOC50_RS31695	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BOC50_RS31700	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BOC50_RS31760	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BOC50_RS31770	COG1175	transmembrane transport
BOC50_RS31775	COG0395	ABC-type sugar transport system, permease component
BOC50_RS31780	COG3842	ATPase activity
BOC50_RS31785	COG0584	glycerophosphoryl diester phosphodiesterase
BOC50_RS31800	COG0069	glutamate synthase activity
BOC50_RS31800	COG0070	glutamate synthase
BOC50_RS31800	COG0067	glutamate synthase
BOC50_RS31815	COG1115	amino acid carrier protein
BOC50_RS31825	COG4178	(ABC) transporter
BOC50_RS31850	COG1127	ABC transporter
BOC50_RS31855	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BOC50_RS31860	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BOC50_RS31885	COG1131	(ABC) transporter
BOC50_RS31890	COG0842	Transport permease protein
BOC50_RS31915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BOC50_RS31925	COG2095	MarC family integral membrane protein
BOC50_RS31975	COG0805	protein transport
BOC50_RS31980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BOC50_RS31985	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BOC50_RS31990	COG0723	plastoquinol--plastocyanin reductase activity
BOC50_RS31995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BOC50_RS32000	COG2857	Cytochrome c1
BOC50_RS32005	COG0625	glutathione transferase activity
BOC50_RS32010	COG2969	positive regulation of protein catabolic process
BOC50_RS32190	COG0308	aminopeptidase N
BOC50_RS32275	COG0443	Heat shock 70 kDa protein
BOC50_RS32290	COG1278	Cold shock
BOC50_RS32295	COG0531	amino acid
BOC50_RS32305	COG3384	dioxygenase
BOC50_RS32315	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BOC50_RS32320	COG2890	protein-(glutamine-N5) methyltransferase activity
BOC50_RS32350	COG0006	proline dipeptidase activity
BOC50_RS32355	COG1335	isochorismatase
BOC50_RS32365	COG0488	(ABC) transporter
BOC50_RS32380	COG0584	glycerophosphoryl diester phosphodiesterase
BOC50_RS32415	COG0012	GTP binding
BOC50_RS32445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BOC50_RS32450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BOC50_RS32465	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BOC50_RS32485	COG0512	Glutamine amidotransferase of anthranilate synthase
BOC50_RS32500	COG0546	phosphoglycolate phosphatase activity
BOC50_RS32505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BOC50_RS32515	COG2967	ApaG domain
BOC50_RS32525	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BOC50_RS32535	COG2050	protein possibly involved in aromatic compounds catabolism
BOC50_RS32540	COG1024	Enoyl-CoA hydratase
BOC50_RS32545	COG0183	Belongs to the thiolase family
BOC50_RS32555	COG1024	Enoyl-CoA hydratase
BOC50_RS32605	COG0243	molybdopterin cofactor binding
BOC50_RS32610	COG0318	PFAM AMP-dependent synthetase and ligase
BOC50_RS32615	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS32635	COG3116	cell division
BOC50_RS32645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BOC50_RS32650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BOC50_RS32685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BOC50_RS32705	COG0678	peroxiredoxin activity
BOC50_RS32730	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BOC50_RS32740	COG0494	nUDIX hydrolase
BOC50_RS32745	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BOC50_RS32760	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BOC50_RS32770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BOC50_RS32775	COG4536	flavin adenine dinucleotide binding
BOC50_RS32785	COG0142	geranyltranstransferase activity
BOC50_RS32830	COG2095	MarC family integral membrane protein
BOC50_RS32835	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BOC50_RS32840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BOC50_RS32895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BOC50_RS32900	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BOC50_RS32915	COG0439	Biotin carboxylase
BOC50_RS32920	COG0511	ligase activity, forming carbon-carbon bonds
BOC50_RS32925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BOC50_RS32930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BOC50_RS32940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BOC50_RS32945	COG3150	esterase
BOC50_RS32950	COG0557	exoribonuclease II activity
BOC50_RS32955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BOC50_RS32960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BOC50_RS32980	COG1414	Transcriptional regulator
BOC50_RS32985	COG3734	2-keto-3-deoxy-galactonokinase
BOC50_RS32995	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS33010	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOC50_RS33015	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS33025	COG0284	orotidine-5'-phosphate decarboxylase activity
BOC50_RS33030	COG1546	Belongs to the CinA family
BOC50_RS33035	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BOC50_RS33065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BOC50_RS33075	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BOC50_RS33080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BOC50_RS33085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BOC50_RS33095	COG2814	Major facilitator Superfamily
BOC50_RS33110	COG0583	DNA-binding transcription factor activity
BOC50_RS33125	COG1301	dicarboxylic acid transport
BOC50_RS33130	COG4266	Belongs to the allantoicase family
BOC50_RS33135	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BOC50_RS33140	COG0735	belongs to the Fur family
BOC50_RS33145	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BOC50_RS33175	COG1466	dna polymerase III delta subunit
BOC50_RS33180	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BOC50_RS33185	COG1981	membrane
BOC50_RS33195	COG1737	Transcriptional regulator
BOC50_RS33195	COG0837	glucose binding
BOC50_RS33210	COG0800	Aldolase
BOC50_RS33230	COG2223	nitrite transmembrane transporter activity
BOC50_RS33235	COG0583	DNA-binding transcription factor activity
BOC50_RS33245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BOC50_RS33250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOC50_RS33255	COG0765	amino acid transport
BOC50_RS33260	COG0765	amino acid transport
BOC50_RS33265	COG1126	abc transporter atp-binding protein
BOC50_RS33315	COG0121	glutamine amidotransferase
BOC50_RS33325	COG0418	dihydroorotase activity
BOC50_RS33360	COG4977	sequence-specific DNA binding
BOC50_RS33360	COG1917	Cupin 2, conserved barrel domain protein
BOC50_RS33365	COG0625	glutathione transferase activity
BOC50_RS33370	COG0625	glutathione transferase activity
BOC50_RS33385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BOC50_RS33395	COG0588	phosphoglycerate mutase activity
BOC50_RS33435	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BOC50_RS33440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BOC50_RS33445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BOC50_RS33450	COG0006	proline dipeptidase activity
BOC50_RS33460	COG0625	glutathione transferase activity
BOC50_RS33470	COG0069	glutamate synthase activity
BOC50_RS33570	COG3008	intermembrane lipid transfer
BOC50_RS33570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BOC50_RS33575	COG2995	paraquat-inducible protein a
BOC50_RS33595	COG2353	YceI-like domain
BOC50_RS33600	COG2353	YceI-like domain
BOC50_RS33615	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BOC50_RS33620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BOC50_RS33625	COG1862	Preprotein translocase
BOC50_RS33635	COG0343	queuine tRNA-ribosyltransferase activity
BOC50_RS33645	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BOC50_RS33650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BOC50_RS33675	COG0783	Belongs to the Dps family
BOC50_RS33705	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BOC50_RS33710	COG2188	Transcriptional regulator
BOC50_RS33720	COG3624	Phosphonate C-P lyase system protein PhnG
BOC50_RS33730	COG3626	phosphonate metabolism
BOC50_RS33735	COG3627	carbon phosphorus lyase activity
BOC50_RS33740	COG4107	phosphonate C-P lyase system protein PhnK
BOC50_RS33745	COG4778	phosphonate C-P lyase system protein PhnL
BOC50_RS33750	COG3454	Phosphonate metabolism
BOC50_RS33755	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BOC50_RS33760	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BOC50_RS33765	COG3639	organic phosphonate transmembrane transporter activity
BOC50_RS33785	COG0247	lactate metabolic process
BOC50_RS33790	COG0277	FAD linked oxidase domain protein
BOC50_RS33795	COG0277	FAD linked oxidase domain protein
BOC50_RS33800	COG0277	FAD linked oxidase domain protein
BOC50_RS33805	COG2096	Adenosyltransferase
BOC50_RS33810	COG1017	nitric oxide dioxygenase activity
BOC50_RS33810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BOC50_RS33820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BOC50_RS33830	COG0312	modulator of DNA gyrase
BOC50_RS33835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BOC50_RS33840	COG3164	Protein of unknown function
BOC50_RS33845	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BOC50_RS33850	COG0497	DNA recombination
BOC50_RS33855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BOC50_RS33895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BOC50_RS33905	COG1428	Deoxynucleoside kinase
BOC50_RS33910	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BOC50_RS33915	COG0617	tRNA 3'-terminal CCA addition
BOC50_RS33925	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BOC50_RS33950	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BOC50_RS33955	COG0586	Pfam SNARE associated Golgi protein
BOC50_RS34055	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BOC50_RS34070	COG1368	sulfuric ester hydrolase activity
BOC50_RS34075	COG0604	alcohol dehydrogenase
BOC50_RS34075	COG1028	Short-chain dehydrogenase reductase Sdr
BOC50_RS34075	COG3321	synthase
BOC50_RS34080	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BOC50_RS34085	COG0156	8-amino-7-oxononanoate synthase activity
BOC50_RS34135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BOC50_RS34140	COG3206	protein involved in exopolysaccharide biosynthesis
BOC50_RS34140	COG0489	protein tyrosine kinase activity
BOC50_RS34150	COG3562	capsule polysaccharide
BOC50_RS34155	COG1045	serine acetyltransferase
BOC50_RS34170	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BOC50_RS34175	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BOC50_RS34180	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BOC50_RS34180	COG0517	IMP dehydrogenase activity
BOC50_RS34215	COG2885	chlorophyll binding
BOC50_RS34240	COG0824	Thioesterase
BOC50_RS34245	COG4221	oxidoreductase activity
BOC50_RS34305	COG0450	alkyl hydroperoxide reductase
BOC50_RS34315	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS34350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BOC50_RS34360	COG2814	Major facilitator Superfamily
BOC50_RS34390	COG2814	Major facilitator Superfamily
BOC50_RS34395	COG0778	Nitroreductase
BOC50_RS34400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BOC50_RS34405	COG0583	DNA-binding transcription factor activity
BOC50_RS34415	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BOC50_RS34450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BOC50_RS34475	COG4774	siderophore transport
BOC50_RS34480	COG1120	ATPase activity
BOC50_RS34490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BOC50_RS34535	COG0730	response to heat
BOC50_RS34550	COG0584	glycerophosphoryl diester phosphodiesterase
BOC50_RS34555	COG1280	lysine exporter protein (LysE YggA)
BOC50_RS34615	COG0604	alcohol dehydrogenase
BOC50_RS34620	COG1733	regulation of RNA biosynthetic process
BOC50_RS34635	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BOC50_RS34655	COG1773	rubredoxin
BOC50_RS34675	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BOC50_RS34750	COG1215	transferase activity, transferring glycosyl groups
BOC50_RS34765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BOC50_RS34780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BOC50_RS34810	COG0859	PFAM glycosyl transferase family 9
BOC50_RS34865	COG1129	ABC transporter
BOC50_RS34875	COG0559	Belongs to the binding-protein-dependent transport system permease family
BOC50_RS34890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BOC50_RS34900	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BOC50_RS34910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BOC50_RS34950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BOC50_RS34955	COG2226	methyltransferase
BOC50_RS34985	COG0762	integral membrane protein
BOC50_RS35040	COG0436	Aminotransferase
BOC50_RS35070	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BOC50_RS35070	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BOC50_RS35095	COG2814	Major facilitator Superfamily
BOC50_RS35110	COG1126	abc transporter atp-binding protein
BOC50_RS35115	COG0765	amino acid transport
BOC50_RS35120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOC50_RS35135	COG0363	glucosamine-6-phosphate deaminase activity
BOC50_RS35140	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BOC50_RS35150	COG1175	transmembrane transport
BOC50_RS35155	COG0395	ABC-type sugar transport system, permease component
BOC50_RS35160	COG3842	ATPase activity
BOC50_RS35165	COG2860	membrane
BOC50_RS35170	COG1193	negative regulation of DNA recombination
BOC50_RS35175	COG0492	ferredoxin-NADP+ reductase activity
BOC50_RS35180	COG1674	ftsk spoiiie
BOC50_RS35185	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BOC50_RS35195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BOC50_RS35225	COG2801	Transposase and inactivated derivatives
BOC50_RS35235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BOC50_RS35240	COG2192	nodulation
BOC50_RS35245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BOC50_RS35250	COG0477	Major facilitator Superfamily
BOC50_RS35255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BOC50_RS35325	COG5377	YqaJ viral recombinase family
BOC50_RS35390	COG0582	viral genome integration into host DNA
BOC50_RS35420	COG2894	cell division
BOC50_RS35440	COG0859	PFAM glycosyl transferase family 9
BOC50_RS35450	COG0477	Major facilitator Superfamily
BOC50_RS35485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BOC50_RS35490	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BOC50_RS35500	COG1561	YicC-like family, N-terminal region
BOC50_RS35515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BOC50_RS35540	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BOC50_RS35550	COG1278	Cold shock
BOC50_RS35555	COG2176	DNA-directed DNA polymerase activity
BOC50_RS35575	COG4772	TonB-dependent receptor
BOC50_RS35635	COG0583	DNA-binding transcription factor activity
BOC50_RS35645	COG0308	aminopeptidase N
BOC50_RS35660	COG2119	membrane
BOC50_RS35670	COG0402	S-adenosylhomocysteine deaminase activity
BOC50_RS35675	COG2252	PERMEase
BOC50_RS35680	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BOC50_RS35700	COG0154	amidase activity
BOC50_RS35710	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BOC50_RS35750	COG3383	formate dehydrogenase (NAD+) activity
BOC50_RS35765	COG1910	domain protein
BOC50_RS35775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BOC50_RS35785	COG0546	phosphoglycolate phosphatase activity
BOC50_RS35815	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BOC50_RS35820	COG1605	Chorismate mutase
BOC50_RS35820	COG0077	Prephenate dehydratase
BOC50_RS35830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BOC50_RS35855	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BOC50_RS35865	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BOC50_RS35890	COG2951	lytic endotransglycosylase activity
BOC50_RS35895	COG0123	including yeast histone deacetylase and acetoin utilization protein
BOC50_RS35905	COG2267	carboxylic ester hydrolase activity
BOC50_RS35915	COG2011	ABC-type metal ion transport system permease component
BOC50_RS35935	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS36005	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BOC50_RS36020	COG0501	Belongs to the peptidase M48B family
BOC50_RS36030	COG0521	Mo-molybdopterin cofactor biosynthetic process
BOC50_RS36035	COG3028	Belongs to the UPF0307 family
BOC50_RS36045	COG0312	modulator of DNA gyrase
BOC50_RS36055	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BOC50_RS36060	COG2204	response regulator
BOC50_RS36085	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BOC50_RS36095	COG0640	Transcriptional regulator
BOC50_RS36115	COG0114	fumarate hydratase activity
BOC50_RS36130	COG0534	Mate efflux family protein
BOC50_RS36135	COG2501	S4 domain
BOC50_RS36150	COG3045	CreA protein
BOC50_RS36165	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BOC50_RS36175	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BOC50_RS36195	COG1322	Protein conserved in bacteria
BOC50_RS36210	COG0303	'Molybdopterin
BOC50_RS36220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BOC50_RS36225	COG1530	ribonuclease E activity
BOC50_RS36240	COG0546	phosphoglycolate phosphatase activity
BOC50_RS36265	COG1399	metal-binding, possibly nucleic acid-binding protein
BOC50_RS36300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BOC50_RS36320	COG3026	antisigma factor binding
BOC50_RS36325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BOC50_RS36340	COG0681	Belongs to the peptidase S26 family
BOC50_RS36345	COG0571	ribonuclease III activity
BOC50_RS36350	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BOC50_RS36375	COG2204	response regulator
BOC50_RS36395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BOC50_RS36415	COG1956	GAF domain-containing protein
BOC50_RS36420	COG0583	DNA-binding transcription factor activity
BOC50_RS36430	COG2153	protein acetylation
BOC50_RS36445	COG1999	signal sequence binding
BOC50_RS36460	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BOC50_RS36465	COG1132	(ABC) transporter
BOC50_RS36470	COG0438	transferase activity, transferring glycosyl groups
BOC50_RS36485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOC50_RS36490	COG0683	leucine binding
BOC50_RS36495	COG3511	phospholipase C
BOC50_RS36515	COG0596	Alpha beta hydrolase
BOC50_RS36525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BOC50_RS36540	COG3394	polysaccharide catabolic process
BOC50_RS36570	COG4598	ABC transporter
BOC50_RS36595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BOC50_RS36630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOC50_RS36640	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BOC50_RS36670	COG1959	2 iron, 2 sulfur cluster binding
BOC50_RS36685	COG2151	metal-sulfur cluster biosynthetic enzyme
BOC50_RS36690	COG0822	iron-sulfur transferase activity
BOC50_RS36695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BOC50_RS36705	COG0396	ATPase activity
BOC50_RS36710	COG0719	Fe-S assembly protein
BOC50_RS36730	COG0840	transmembrane signaling receptor activity
BOC50_RS36735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BOC50_RS36740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BOC50_RS36760	COG0826	peptidase U32
BOC50_RS36765	COG0826	peptidase U32
BOC50_RS36770	COG3154	lipid carrier protein
BOC50_RS36810	COG2151	metal-sulfur cluster biosynthetic enzyme
BOC50_RS36830	COG0415	Belongs to the DNA photolyase family
BOC50_RS36835	COG0529	Catalyzes the synthesis of activated sulfate
BOC50_RS36885	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BOC50_RS36900	COG0402	S-adenosylhomocysteine deaminase activity
BOC50_RS36940	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BOC50_RS36945	COG0174	glutamine synthetase
BOC50_RS36960	COG3668	Plasmid stabilization system
BOC50_RS36980	COG0583	DNA-binding transcription factor activity
BOC50_RS36985	COG1960	acyl-CoA dehydrogenase activity
BOC50_RS37000	COG0477	Major facilitator Superfamily
BOC50_RS37010	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BOC50_RS37010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BOC50_RS37015	COG1643	Atp-dependent helicase
BOC50_RS37040	COG1546	Belongs to the CinA family
BOC50_RS37040	COG1058	Belongs to the CinA family
BOC50_RS37055	COG0174	glutamine synthetase
BOC50_RS37295	COG2197	response regulator
BOC50_RS37300	COG4585	Histidine kinase
BOC50_RS37305	COG2181	nitrate reductase activity
BOC50_RS37310	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BOC50_RS37315	COG1140	nitrate reductase beta subunit
BOC50_RS37320	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BOC50_RS37325	COG2223	nitrite transmembrane transporter activity
BOC50_RS37350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BOC50_RS37355	COG0339	signal peptide processing
BOC50_RS37380	COG4566	intracellular signal transduction
BOC50_RS37390	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BOC50_RS37395	COG0508	dehydrogenase complex catalyzes the overall conversion of
BOC50_RS37400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BOC50_RS37465	COG5295	Hep Hag repeat protein
BOC50_RS37465	COG5295	Hep Hag repeat protein