locus-tag	class	description
JE55_RS00005	COG0560	Phosphoserine phosphatase
JE55_RS00010	COG0626	cystathionine gamma-synthase activity
JE55_RS00020	COG0183	Belongs to the thiolase family
JE55_RS00040	COG1028	Short-chain dehydrogenase reductase Sdr
JE55_RS00045	COG0183	Belongs to the thiolase family
JE55_RS00050	COG3243	poly(R)-hydroxyalkanoic acid synthase
JE55_RS00055	COG1496	oxidoreductase activity
JE55_RS00060	COG0564	pseudouridine synthase activity
JE55_RS00070	COG1199	ATP-dependent helicase activity
JE55_RS00085	COG2183	response to ionizing radiation
JE55_RS00095	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JE55_RS00115	COG0330	HflC and HflK could
JE55_RS00120	COG0330	HflC and HflK could
JE55_RS00125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JE55_RS00140	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JE55_RS00175	COG0670	Belongs to the BI1 family
JE55_RS00220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JE55_RS00235	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JE55_RS00250	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JE55_RS00255	COG0789	Transcriptional regulator
JE55_RS00260	COG0477	Major facilitator Superfamily
JE55_RS00265	COG3228	Belongs to the MtfA family
JE55_RS00280	COG0534	Mate efflux family protein
JE55_RS00305	COG0542	response to heat
JE55_RS00310	COG1959	2 iron, 2 sulfur cluster binding
JE55_RS00315	COG2346	COG2346, Truncated hemoglobins
JE55_RS00320	COG0314	molybdopterin synthase activity
JE55_RS00325	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JE55_RS00345	COG0436	Aminotransferase
JE55_RS00355	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JE55_RS00360	COG2076	Multidrug Resistance protein
JE55_RS00365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JE55_RS00370	COG0463	Glycosyl transferase, family 2
JE55_RS00380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JE55_RS00380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JE55_RS00385	COG0726	polysaccharide deacetylase
JE55_RS00390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JE55_RS00395	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JE55_RS00400	COG0791	NLP P60 protein
JE55_RS00405	COG0306	phosphate transporter
JE55_RS00460	COG0583	DNA-binding transcription factor activity
JE55_RS00465	COG3960	tartronate-semialdehyde synthase activity
JE55_RS00470	COG3622	Belongs to the hyi family
JE55_RS00475	COG2084	Dehydrogenase
JE55_RS00480	COG1652	LysM domain
JE55_RS00490	COG0252	asparaginase activity
JE55_RS00515	COG0438	transferase activity, transferring glycosyl groups
JE55_RS00540	COG0084	hydrolase, TatD family'
JE55_RS00545	COG1247	-acetyltransferase
JE55_RS00560	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JE55_RS00565	COG0354	folic acid binding
JE55_RS00580	COG0657	acetylesterase activity
JE55_RS00585	COG2130	NADP-dependent
JE55_RS00605	COG0183	Belongs to the thiolase family
JE55_RS00610	COG1335	isochorismatase
JE55_RS00615	COG1024	Enoyl-CoA hydratase
JE55_RS00615	COG1250	3-hydroxyacyl-CoA dehydrogenase
JE55_RS00620	COG0318	PFAM AMP-dependent synthetase and ligase
JE55_RS00645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JE55_RS00655	COG0047	phosphoribosylformylglycinamidine synthase activity
JE55_RS00655	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JE55_RS00665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JE55_RS00680	COG4181	ATPase activity
JE55_RS00730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JE55_RS00750	COG1929	Belongs to the glycerate kinase type-1 family
JE55_RS00755	COG1846	Transcriptional regulator
JE55_RS00760	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JE55_RS00870	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JE55_RS00885	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JE55_RS00950	COG3360	Dodecin
JE55_RS00955	COG0583	DNA-binding transcription factor activity
JE55_RS00965	COG2351	hydroxyisourate hydrolase activity
JE55_RS00980	COG4266	Belongs to the allantoicase family
JE55_RS00985	COG3648	Uricase
JE55_RS00985	COG3195	allantoin biosynthetic process
JE55_RS01000	COG1953	Uracil, thiamine, allantoin
JE55_RS01010	COG1619	proteins homologs of microcin C7 resistance protein MccF
JE55_RS01030	COG2814	Major facilitator Superfamily
JE55_RS01065	COG0697	spore germination
JE55_RS01075	COG2867	negative regulation of translational initiation
JE55_RS01085	COG0330	HflC and HflK could
JE55_RS01120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JE55_RS01160	COG0750	zinc metalloprotease
JE55_RS01175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JE55_RS01205	COG0024	Methionine aminopeptidase
JE55_RS01215	COG1187	pseudouridine synthase activity
JE55_RS01220	COG0242	peptide deformylase activity
JE55_RS01260	COG1393	Belongs to the ArsC family
JE55_RS01270	COG2890	protein-(glutamine-N5) methyltransferase activity
JE55_RS01285	COG0386	Belongs to the glutathione peroxidase family
JE55_RS01290	COG0488	(ABC) transporter
JE55_RS01310	COG0477	Major facilitator Superfamily
JE55_RS01315	COG0351	phosphomethylpyrimidine kinase
JE55_RS01330	COG1573	uracil-dna glycosylase
JE55_RS01340	COG1214	PFAM Peptidase M22, glycoprotease
JE55_RS01350	COG0513	Belongs to the DEAD box helicase family
JE55_RS01355	COG2224	Isocitrate lyase
JE55_RS01365	COG0583	DNA-binding transcription factor activity
JE55_RS01375	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JE55_RS01435	COG1752	Esterase of the alpha-beta hydrolase superfamily
JE55_RS01440	COG0791	NLP P60 protein
JE55_RS01445	COG4172	Belongs to the ABC transporter superfamily
JE55_RS01450	COG4239	(ABC) transporter, permease
JE55_RS01455	COG4174	ABC transporter (Permease)
JE55_RS01460	COG4166	transmembrane transport
JE55_RS01480	COG0243	molybdopterin cofactor binding
JE55_RS01495	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JE55_RS01510	COG0024	Methionine aminopeptidase
JE55_RS01525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JE55_RS01545	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JE55_RS01560	COG3958	Transketolase
JE55_RS01565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JE55_RS01585	COG2175	clavaminate synthase activity
JE55_RS01610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JE55_RS01615	COG0529	Catalyzes the synthesis of activated sulfate
JE55_RS01615	COG2895	sulfate adenylyltransferase (ATP) activity
JE55_RS01625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JE55_RS01660	COG0527	aspartate kinase activity
JE55_RS01665	COG0037	tRNA processing
JE55_RS01690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JE55_RS01700	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JE55_RS01705	COG1045	serine acetyltransferase
JE55_RS01715	COG0483	inositol monophosphate 1-phosphatase activity
JE55_RS01735	COG3311	Transcriptional regulator
JE55_RS02000	COG2850	peptidyl-arginine hydroxylation
JE55_RS02005	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JE55_RS02010	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
JE55_RS02015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JE55_RS02025	COG0180	Tryptophanyl-tRNA synthetase
JE55_RS02030	COG1994	Peptidase M50
JE55_RS02035	COG0009	L-threonylcarbamoyladenylate synthase
JE55_RS02040	COG0613	PHP domain protein
JE55_RS02045	COG0596	Alpha beta hydrolase
JE55_RS02050	COG2833	Protein of unknown function (DUF455)
JE55_RS02060	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JE55_RS02070	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JE55_RS02090	COG2267	carboxylic ester hydrolase activity
JE55_RS02095	COG0658	competence protein
JE55_RS02095	COG2333	competence protein COMEC
JE55_RS02100	COG0084	hydrolase, TatD family'
JE55_RS02105	COG1136	(ABC) transporter
JE55_RS02120	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JE55_RS02140	COG2975	iron-sulfur cluster assembly
JE55_RS02160	COG0316	Belongs to the HesB IscA family
JE55_RS02165	COG0822	iron-sulfur transferase activity
JE55_RS02170	COG1104	cysteine desulfurase activity
JE55_RS02180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JE55_RS02200	COG1414	Transcriptional regulator
JE55_RS02215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JE55_RS02220	COG0508	dehydrogenase complex catalyzes the overall conversion of
JE55_RS02225	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JE55_RS02235	COG4566	intracellular signal transduction
JE55_RS02245	COG0339	signal peptide processing
JE55_RS02250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JE55_RS02265	COG2223	nitrite transmembrane transporter activity
JE55_RS02270	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JE55_RS02275	COG1140	nitrate reductase beta subunit
JE55_RS02280	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JE55_RS02285	COG2181	nitrate reductase activity
JE55_RS02290	COG4585	Histidine kinase
JE55_RS02295	COG2197	response regulator
JE55_RS02315	COG0174	glutamine synthetase
JE55_RS02325	COG1546	Belongs to the CinA family
JE55_RS02325	COG1058	Belongs to the CinA family
JE55_RS02345	COG1643	Atp-dependent helicase
JE55_RS02350	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JE55_RS02350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JE55_RS02360	COG0477	Major facilitator Superfamily
JE55_RS02370	COG1960	acyl-CoA dehydrogenase activity
JE55_RS02375	COG0583	DNA-binding transcription factor activity
JE55_RS02400	COG0174	glutamine synthetase
JE55_RS02405	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JE55_RS02430	COG0402	S-adenosylhomocysteine deaminase activity
JE55_RS02445	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JE55_RS02480	COG0529	Catalyzes the synthesis of activated sulfate
JE55_RS02485	COG0415	Belongs to the DNA photolyase family
JE55_RS02500	COG2151	metal-sulfur cluster biosynthetic enzyme
JE55_RS02535	COG3154	lipid carrier protein
JE55_RS02540	COG0826	peptidase U32
JE55_RS02545	COG0826	peptidase U32
JE55_RS02560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JE55_RS02565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JE55_RS02570	COG0840	transmembrane signaling receptor activity
JE55_RS02580	COG0719	Fe-S assembly protein
JE55_RS02585	COG0396	ATPase activity
JE55_RS02595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JE55_RS02600	COG0822	iron-sulfur transferase activity
JE55_RS02605	COG2151	metal-sulfur cluster biosynthetic enzyme
JE55_RS02615	COG1959	2 iron, 2 sulfur cluster binding
JE55_RS02645	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JE55_RS02655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JE55_RS02690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JE55_RS02725	COG3394	polysaccharide catabolic process
JE55_RS02740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JE55_RS02745	COG0596	Alpha beta hydrolase
JE55_RS02750	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JE55_RS02760	COG3511	phospholipase C
JE55_RS02765	COG0683	leucine binding
JE55_RS02770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JE55_RS02785	COG0438	transferase activity, transferring glycosyl groups
JE55_RS02790	COG1132	(ABC) transporter
JE55_RS02795	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JE55_RS02805	COG1999	signal sequence binding
JE55_RS02820	COG2153	protein acetylation
JE55_RS02830	COG0583	DNA-binding transcription factor activity
JE55_RS02835	COG1956	GAF domain-containing protein
JE55_RS02985	COG1674	ftsk spoiiie
JE55_RS03070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JE55_RS03090	COG2204	response regulator
JE55_RS03105	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JE55_RS03115	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JE55_RS03120	COG0571	ribonuclease III activity
JE55_RS03125	COG0681	Belongs to the peptidase S26 family
JE55_RS03140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JE55_RS03145	COG3026	antisigma factor binding
JE55_RS03165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JE55_RS03200	COG1399	metal-binding, possibly nucleic acid-binding protein
JE55_RS03225	COG0546	phosphoglycolate phosphatase activity
JE55_RS03235	COG1530	ribonuclease E activity
JE55_RS03240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JE55_RS03250	COG0303	'Molybdopterin
JE55_RS03265	COG1322	Protein conserved in bacteria
JE55_RS03285	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JE55_RS03290	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JE55_RS03305	COG3045	CreA protein
JE55_RS03320	COG2501	S4 domain
JE55_RS03325	COG0534	Mate efflux family protein
JE55_RS03335	COG0114	fumarate hydratase activity
JE55_RS03350	COG0640	Transcriptional regulator
JE55_RS03360	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JE55_RS03395	COG2204	response regulator
JE55_RS03400	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JE55_RS03410	COG0312	modulator of DNA gyrase
JE55_RS03415	COG3028	Belongs to the UPF0307 family
JE55_RS03420	COG0521	Mo-molybdopterin cofactor biosynthetic process
JE55_RS03430	COG0501	Belongs to the peptidase M48B family
JE55_RS03445	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JE55_RS03505	COG1960	acyl-CoA dehydrogenase activity
JE55_RS03525	COG2011	ABC-type metal ion transport system permease component
JE55_RS03535	COG2267	carboxylic ester hydrolase activity
JE55_RS03540	COG0123	including yeast histone deacetylase and acetoin utilization protein
JE55_RS03545	COG2951	lytic endotransglycosylase activity
JE55_RS03570	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JE55_RS03580	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JE55_RS03605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JE55_RS03610	COG1605	Chorismate mutase
JE55_RS03610	COG0077	Prephenate dehydratase
JE55_RS03615	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JE55_RS03640	COG0546	phosphoglycolate phosphatase activity
JE55_RS03645	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JE55_RS03655	COG1910	domain protein
JE55_RS03670	COG3383	formate dehydrogenase (NAD+) activity
JE55_RS03695	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JE55_RS03700	COG0154	amidase activity
JE55_RS03715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JE55_RS03720	COG2252	PERMEase
JE55_RS03725	COG0402	S-adenosylhomocysteine deaminase activity
JE55_RS03735	COG2119	membrane
JE55_RS03745	COG0308	aminopeptidase N
JE55_RS03755	COG0583	DNA-binding transcription factor activity
JE55_RS03805	COG4772	TonB-dependent receptor
JE55_RS03825	COG2176	DNA-directed DNA polymerase activity
JE55_RS03830	COG1278	Cold shock
JE55_RS03840	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JE55_RS03860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JE55_RS03875	COG1561	YicC-like family, N-terminal region
JE55_RS03885	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JE55_RS03890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JE55_RS03920	COG0477	Major facilitator Superfamily
JE55_RS03930	COG0859	PFAM glycosyl transferase family 9
JE55_RS03955	COG2894	cell division
JE55_RS03995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JE55_RS04000	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JE55_RS04005	COG1674	ftsk spoiiie
JE55_RS04010	COG0492	ferredoxin-NADP+ reductase activity
JE55_RS04015	COG1193	negative regulation of DNA recombination
JE55_RS04020	COG2860	membrane
JE55_RS04025	COG3842	ATPase activity
JE55_RS04030	COG0395	ABC-type sugar transport system, permease component
JE55_RS04035	COG1175	transmembrane transport
JE55_RS04045	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JE55_RS04050	COG0363	glucosamine-6-phosphate deaminase activity
JE55_RS04055	COG0837	glucose binding
JE55_RS04055	COG1737	Transcriptional regulator
JE55_RS04060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JE55_RS04065	COG0765	amino acid transport
JE55_RS04070	COG1126	abc transporter atp-binding protein
JE55_RS04085	COG2814	Major facilitator Superfamily
JE55_RS04105	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JE55_RS04105	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JE55_RS04115	COG0653	protein targeting
JE55_RS04135	COG0436	Aminotransferase
JE55_RS04170	COG0762	integral membrane protein
JE55_RS04190	COG2226	methyltransferase
JE55_RS04195	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JE55_RS04230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JE55_RS04240	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JE55_RS04250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JE55_RS04260	COG0559	Belongs to the binding-protein-dependent transport system permease family
JE55_RS04270	COG1129	ABC transporter
JE55_RS04325	COG0859	PFAM glycosyl transferase family 9
JE55_RS04350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JE55_RS04365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JE55_RS04380	COG1215	transferase activity, transferring glycosyl groups
JE55_RS04455	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JE55_RS04475	COG1773	rubredoxin
JE55_RS04490	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JE55_RS04500	COG1733	regulation of RNA biosynthetic process
JE55_RS04505	COG0604	alcohol dehydrogenase
JE55_RS04555	COG1280	lysine exporter protein (LysE YggA)
JE55_RS04565	COG0584	glycerophosphoryl diester phosphodiesterase
JE55_RS04575	COG0730	response to heat
JE55_RS04615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JE55_RS04625	COG1120	ATPase activity
JE55_RS04630	COG4774	siderophore transport
JE55_RS04650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JE55_RS04675	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JE55_RS04680	COG0583	DNA-binding transcription factor activity
JE55_RS04685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JE55_RS04690	COG0778	Nitroreductase
JE55_RS04695	COG2814	Major facilitator Superfamily
JE55_RS04720	COG2814	Major facilitator Superfamily
JE55_RS04730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JE55_RS04760	COG1960	acyl-CoA dehydrogenase activity
JE55_RS04770	COG0450	alkyl hydroperoxide reductase
JE55_RS04825	COG4221	oxidoreductase activity
JE55_RS04830	COG0824	Thioesterase
JE55_RS04855	COG2885	chlorophyll binding
JE55_RS04890	COG0517	IMP dehydrogenase activity
JE55_RS04890	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JE55_RS04895	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JE55_RS04900	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JE55_RS04915	COG1045	serine acetyltransferase
JE55_RS04920	COG3562	capsule polysaccharide
JE55_RS04930	COG0489	protein tyrosine kinase activity
JE55_RS04930	COG3206	protein involved in exopolysaccharide biosynthesis
JE55_RS04935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JE55_RS04980	COG0156	8-amino-7-oxononanoate synthase activity
JE55_RS04985	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JE55_RS04990	COG0604	alcohol dehydrogenase
JE55_RS04990	COG1028	Short-chain dehydrogenase reductase Sdr
JE55_RS04990	COG3321	synthase
JE55_RS04995	COG1368	sulfuric ester hydrolase activity
JE55_RS05010	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JE55_RS05110	COG0586	Pfam SNARE associated Golgi protein
JE55_RS05115	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JE55_RS05135	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JE55_RS05145	COG0617	tRNA 3'-terminal CCA addition
JE55_RS05150	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JE55_RS05155	COG1428	Deoxynucleoside kinase
JE55_RS05165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JE55_RS05205	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JE55_RS05210	COG0497	DNA recombination
JE55_RS05215	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JE55_RS05220	COG3164	Protein of unknown function
JE55_RS05225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JE55_RS05230	COG0312	modulator of DNA gyrase
JE55_RS05235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JE55_RS05245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JE55_RS05245	COG1017	nitric oxide dioxygenase activity
JE55_RS05250	COG2096	Adenosyltransferase
JE55_RS05255	COG0277	FAD linked oxidase domain protein
JE55_RS05260	COG0277	FAD linked oxidase domain protein
JE55_RS05265	COG0277	FAD linked oxidase domain protein
JE55_RS05270	COG0247	lactate metabolic process
JE55_RS05285	COG3639	organic phosphonate transmembrane transporter activity
JE55_RS05290	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
JE55_RS05300	COG3454	Phosphonate metabolism
JE55_RS05305	COG4778	phosphonate C-P lyase system protein PhnL
JE55_RS05310	COG4107	phosphonate C-P lyase system protein PhnK
JE55_RS05315	COG3627	carbon phosphorus lyase activity
JE55_RS05320	COG3626	phosphonate metabolism
JE55_RS05330	COG3624	Phosphonate C-P lyase system protein PhnG
JE55_RS05335	COG2188	Transcriptional regulator
JE55_RS05340	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
JE55_RS05345	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
JE55_RS05365	COG0783	Belongs to the Dps family
JE55_RS05385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JE55_RS05395	COG0343	queuine tRNA-ribosyltransferase activity
JE55_RS05400	COG1862	Preprotein translocase
JE55_RS05405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JE55_RS05410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JE55_RS05420	COG2353	YceI-like domain
JE55_RS05425	COG2353	YceI-like domain
JE55_RS05445	COG2995	paraquat-inducible protein a
JE55_RS05450	COG3008	intermembrane lipid transfer
JE55_RS05450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JE55_RS05520	COG0069	glutamate synthase activity
JE55_RS05525	COG0625	glutathione transferase activity
JE55_RS05530	COG0006	proline dipeptidase activity
JE55_RS05535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JE55_RS05540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JE55_RS05545	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JE55_RS05585	COG0588	phosphoglycerate mutase activity
JE55_RS05595	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JE55_RS05605	COG0625	glutathione transferase activity
JE55_RS05610	COG0625	glutathione transferase activity
JE55_RS05615	COG1917	Cupin 2, conserved barrel domain protein
JE55_RS05615	COG4977	sequence-specific DNA binding
JE55_RS05645	COG0418	dihydroorotase activity
JE55_RS05650	COG0121	glutamine amidotransferase
JE55_RS05675	COG0459	protein refolding
JE55_RS05690	COG1126	abc transporter atp-binding protein
JE55_RS05695	COG0765	amino acid transport
JE55_RS05700	COG0765	amino acid transport
JE55_RS05705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JE55_RS05710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JE55_RS05715	COG0583	DNA-binding transcription factor activity
JE55_RS05720	COG2223	nitrite transmembrane transporter activity
JE55_RS05740	COG0800	Aldolase
JE55_RS05750	COG1737	Transcriptional regulator
JE55_RS05750	COG0837	glucose binding
JE55_RS05755	COG1981	membrane
JE55_RS05760	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JE55_RS05765	COG1466	dna polymerase III delta subunit
JE55_RS05795	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JE55_RS05800	COG0735	belongs to the Fur family
JE55_RS05805	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
JE55_RS05810	COG4266	Belongs to the allantoicase family
JE55_RS05815	COG1301	dicarboxylic acid transport
JE55_RS05825	COG0583	DNA-binding transcription factor activity
JE55_RS05840	COG2814	Major facilitator Superfamily
JE55_RS05845	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JE55_RS05850	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JE55_RS05855	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JE55_RS05865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JE55_RS05895	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JE55_RS05900	COG1546	Belongs to the CinA family
JE55_RS05905	COG0284	orotidine-5'-phosphate decarboxylase activity
JE55_RS05915	COG1028	Short-chain dehydrogenase reductase Sdr
JE55_RS05920	COG1172	Belongs to the binding-protein-dependent transport system permease family
JE55_RS05935	COG1028	Short-chain dehydrogenase reductase Sdr
JE55_RS05945	COG3734	2-keto-3-deoxy-galactonokinase
JE55_RS05950	COG1414	Transcriptional regulator
JE55_RS05965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JE55_RS05970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JE55_RS05975	COG0557	exoribonuclease II activity
JE55_RS05980	COG3150	esterase
JE55_RS05985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JE55_RS05995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JE55_RS06000	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JE55_RS06005	COG0511	ligase activity, forming carbon-carbon bonds
JE55_RS06010	COG0439	Biotin carboxylase
JE55_RS06025	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JE55_RS06030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JE55_RS06070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JE55_RS06075	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JE55_RS06080	COG2095	MarC family integral membrane protein
JE55_RS06120	COG0142	geranyltranstransferase activity
JE55_RS06200	COG4536	flavin adenine dinucleotide binding
JE55_RS06205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JE55_RS06215	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JE55_RS06230	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JE55_RS06235	COG0494	nUDIX hydrolase
JE55_RS06270	COG0678	peroxiredoxin activity
JE55_RS06285	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JE55_RS06320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JE55_RS06325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JE55_RS06335	COG3116	cell division
JE55_RS06355	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JE55_RS06360	COG0318	PFAM AMP-dependent synthetase and ligase
JE55_RS06365	COG0243	molybdopterin cofactor binding
JE55_RS06395	COG1024	Enoyl-CoA hydratase
JE55_RS06405	COG0183	Belongs to the thiolase family
JE55_RS06410	COG1024	Enoyl-CoA hydratase
JE55_RS06415	COG2050	protein possibly involved in aromatic compounds catabolism
JE55_RS06425	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
JE55_RS06435	COG2967	ApaG domain
JE55_RS06440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JE55_RS06445	COG0546	phosphoglycolate phosphatase activity
JE55_RS06455	COG0512	Glutamine amidotransferase of anthranilate synthase
JE55_RS06475	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JE55_RS06490	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JE55_RS06495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JE55_RS06510	COG0012	GTP binding
JE55_RS06545	COG0584	glycerophosphoryl diester phosphodiesterase
JE55_RS06560	COG0488	(ABC) transporter
JE55_RS06570	COG1335	isochorismatase
JE55_RS06580	COG0006	proline dipeptidase activity
JE55_RS06610	COG2890	protein-(glutamine-N5) methyltransferase activity
JE55_RS06615	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JE55_RS06625	COG3384	dioxygenase
JE55_RS06630	COG0531	amino acid
JE55_RS06635	COG1278	Cold shock
JE55_RS06640	COG0443	Heat shock 70 kDa protein
JE55_RS06690	COG0308	aminopeptidase N
JE55_RS06900	COG2969	positive regulation of protein catabolic process
JE55_RS06905	COG0625	glutathione transferase activity
JE55_RS06910	COG2857	Cytochrome c1
JE55_RS06915	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JE55_RS06920	COG0723	plastoquinol--plastocyanin reductase activity
JE55_RS06925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JE55_RS06930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JE55_RS06940	COG0805	protein transport
JE55_RS06990	COG2095	MarC family integral membrane protein
JE55_RS07000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JE55_RS07025	COG0842	Transport permease protein
JE55_RS07030	COG1131	(ABC) transporter
JE55_RS07050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JE55_RS07055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JE55_RS07060	COG1127	ABC transporter
JE55_RS07085	COG4178	(ABC) transporter
JE55_RS07100	COG1115	amino acid carrier protein
JE55_RS07110	COG0067	glutamate synthase
JE55_RS07110	COG0069	glutamate synthase activity
JE55_RS07110	COG0070	glutamate synthase
JE55_RS07125	COG0584	glycerophosphoryl diester phosphodiesterase
JE55_RS07130	COG3842	ATPase activity
JE55_RS07135	COG0395	ABC-type sugar transport system, permease component
JE55_RS07140	COG1175	transmembrane transport
JE55_RS07150	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JE55_RS07205	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JE55_RS07210	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JE55_RS07215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JE55_RS07220	COG1333	cytochrome c biogenesis protein
JE55_RS07240	COG4232	protein-disulfide reductase activity
JE55_RS07285	COG0201	protein transport
JE55_RS07415	COG0514	ATP-dependent DNA helicase (RecQ)
JE55_RS07460	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JE55_RS07520	COG3396	Phenylacetate-CoA oxygenase
JE55_RS07525	COG3460	Phenylacetate-CoA oxygenase
JE55_RS07530	COG3396	Phenylacetate-CoA oxygenase
JE55_RS07535	COG2151	metal-sulfur cluster biosynthetic enzyme
JE55_RS07540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JE55_RS07560	COG1522	sequence-specific DNA binding
JE55_RS07580	COG0280	phosphate acetyltransferase
JE55_RS07580	COG0281	malic enzyme
JE55_RS07585	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JE55_RS07590	COG1881	PFAM PEBP family protein
JE55_RS07600	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JE55_RS07620	COG3047	cAMP biosynthetic process
JE55_RS07625	COG0583	DNA-binding transcription factor activity
JE55_RS07630	COG2814	Major facilitator Superfamily
JE55_RS07635	COG1280	lysine exporter protein (LysE YggA)
JE55_RS07640	COG2084	Dehydrogenase
JE55_RS07670	COG1113	amino acid transport
JE55_RS07690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JE55_RS07695	COG1061	Type III restriction enzyme res subunit
JE55_RS07700	COG1002	Type II restriction enzyme, methylase subunits
JE55_RS07730	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JE55_RS07740	COG3311	Transcriptional regulator
JE55_RS07760	COG2963	transposase activity
JE55_RS07765	COG2801	Transposase and inactivated derivatives
JE55_RS07785	COG2823	Periplasmic or secreted lipoprotein
JE55_RS07790	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JE55_RS07810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JE55_RS07820	COG1522	sequence-specific DNA binding
JE55_RS07825	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JE55_RS07850	COG2070	2-Nitropropane dioxygenase
JE55_RS07865	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JE55_RS07870	COG1950	PFAM Membrane protein of
JE55_RS07895	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JE55_RS07900	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JE55_RS07920	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
JE55_RS07925	COG0745	RESPONSE REGULATOR receiver
JE55_RS07930	COG2201	protein-glutamate methylesterase activity
JE55_RS07940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JE55_RS07960	COG2201	protein-glutamate methylesterase activity
JE55_RS07965	COG1360	Flagellar Motor Protein
JE55_RS07985	COG0438	transferase activity, transferring glycosyl groups
JE55_RS07995	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JE55_RS08000	COG0561	phosphatase activity
JE55_RS08010	COG0519	Catalyzes the synthesis of GMP from XMP
JE55_RS08045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JE55_RS08060	COG1028	Short-chain dehydrogenase reductase Sdr
JE55_RS08125	COG2267	carboxylic ester hydrolase activity
JE55_RS08145	COG3397	chitin binding
JE55_RS08180	COG0582	viral genome integration into host DNA
JE55_RS08190	COG3245	cytochrome
JE55_RS08195	COG0210	DNA helicase
JE55_RS08210	COG0673	inositol 2-dehydrogenase activity
JE55_RS08225	COG0509	glycine decarboxylation via glycine cleavage system
JE55_RS08240	COG1760	l-serine dehydratase
JE55_RS08265	COG1012	belongs to the aldehyde dehydrogenase family
JE55_RS08275	COG4302	ethanolamine ammonia-lyase activity
JE55_RS08280	COG4303	Ethanolamine ammonia lyase large subunit
JE55_RS08285	COG0531	amino acid
JE55_RS08305	COG0668	transmembrane transport
JE55_RS08325	COG0789	Transcriptional regulator
JE55_RS08335	COG0277	FAD linked oxidase domain protein
JE55_RS08350	COG0436	Aminotransferase
JE55_RS08360	COG1960	acyl-CoA dehydrogenase activity
JE55_RS08375	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JE55_RS08375	COG0506	proline dehydrogenase activity
JE55_RS08375	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JE55_RS08385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JE55_RS08400	COG1832	CoA-binding protein
JE55_RS08405	COG0318	PFAM AMP-dependent synthetase and ligase
JE55_RS08450	COG0356	it plays a direct role in the translocation of protons across the membrane
JE55_RS08460	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JE55_RS08465	COG1475	DNA binding
JE55_RS08470	COG1192	Involved in chromosome partitioning
JE55_RS08515	COG0559	Belongs to the binding-protein-dependent transport system permease family
JE55_RS08535	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JE55_RS08545	COG0583	DNA-binding transcription factor activity
JE55_RS08555	COG1522	sequence-specific DNA binding
JE55_RS08560	COG3186	Phenylalanine-4-hydroxylase
JE55_RS08580	COG0642	Histidine kinase
JE55_RS08595	COG1902	pentaerythritol trinitrate reductase activity
JE55_RS08600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JE55_RS08600	COG0519	Catalyzes the synthesis of GMP from XMP
JE55_RS08630	COG0523	cobalamin synthesis protein
JE55_RS08650	COG1459	type II secretion system
JE55_RS08665	COG2165	general secretion pathway protein
JE55_RS08710	COG1846	Transcriptional regulator
JE55_RS08715	COG2814	Major facilitator Superfamily
JE55_RS08720	COG0583	DNA-binding transcription factor activity
JE55_RS08730	COG1346	cytolysis
JE55_RS08745	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JE55_RS08760	COG1987	bacterial-type flagellum assembly
JE55_RS08770	COG0789	Transcriptional regulator
JE55_RS08785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JE55_RS08795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JE55_RS08810	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JE55_RS08825	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JE55_RS08885	COG1695	Transcriptional regulator
JE55_RS08910	COG1960	acyl-CoA dehydrogenase activity
JE55_RS08915	COG0183	Belongs to the thiolase family
JE55_RS08920	COG1250	3-hydroxyacyl-CoA dehydrogenase
JE55_RS08920	COG1024	Enoyl-CoA hydratase
JE55_RS08925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JE55_RS08965	COG0753	catalase activity
JE55_RS08980	COG0592	DNA-directed DNA polymerase activity
JE55_RS09020	COG0582	viral genome integration into host DNA
JE55_RS09080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JE55_RS09100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JE55_RS09100	COG2169	Transcriptional regulator
JE55_RS09115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JE55_RS09135	COG0583	DNA-binding transcription factor activity
JE55_RS09150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JE55_RS09155	COG4695	Portal protein
JE55_RS09190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JE55_RS09195	COG0583	DNA-binding transcription factor activity
JE55_RS09210	COG0758	DNA mediated transformation
JE55_RS09215	COG0242	peptide deformylase activity
JE55_RS09240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JE55_RS09240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JE55_RS09250	COG5000	phosphorelay sensor kinase activity
JE55_RS09255	COG2204	response regulator
JE55_RS09270	COG0602	queuosine metabolic process
JE55_RS09275	COG0720	synthase
JE55_RS09290	COG0772	Belongs to the SEDS family
JE55_RS09295	COG0768	penicillin binding
JE55_RS09310	COG1077	Cell shape determining protein MreB Mrl
JE55_RS09330	COG2326	polyphosphate kinase activity
JE55_RS09335	COG0708	Exodeoxyribonuclease III
JE55_RS09345	COG1064	alcohol dehydrogenase
JE55_RS09350	COG2207	Transcriptional regulator
JE55_RS09360	COG2814	Major facilitator Superfamily
JE55_RS09375	COG1309	transcriptional regulator
JE55_RS09400	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JE55_RS09420	COG0523	cobalamin synthesis protein
JE55_RS09430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JE55_RS09445	COG1560	Kdo2-lipid A biosynthetic process
JE55_RS09475	COG0667	Aldo Keto reductase
JE55_RS09500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JE55_RS09515	COG1960	acyl-CoA dehydrogenase activity
JE55_RS09575	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JE55_RS09590	COG0531	amino acid
JE55_RS09610	COG1280	lysine exporter protein (LysE YggA)
JE55_RS09615	COG3568	Endonuclease Exonuclease Phosphatase
JE55_RS09635	COG0579	oxidoreductase
JE55_RS09650	COG0747	negative chemotaxis
JE55_RS09655	COG0601	transmembrane transport
JE55_RS09660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JE55_RS09665	COG0444	Belongs to the ABC transporter superfamily
JE55_RS09670	COG4608	Belongs to the ABC transporter superfamily
JE55_RS09700	COG1984	allophanate hydrolase subunit 2
JE55_RS09705	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JE55_RS09715	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JE55_RS09720	COG0741	lytic transglycosylase activity
JE55_RS09750	COG2747	anti-sigma28 factor FlgM
JE55_RS09760	COG1815	bacterial-type flagellum-dependent cell motility
JE55_RS09765	COG1558	bacterial-type flagellum-dependent cell motility
JE55_RS09770	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JE55_RS09775	COG1749	Flagellar hook protein flgE
JE55_RS09790	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JE55_RS09795	COG1706	bacterial-type flagellum-dependent cell motility
JE55_RS09805	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JE55_RS09815	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JE55_RS09820	COG2233	PERMEase
JE55_RS09825	COG0583	DNA-binding transcription factor activity
JE55_RS09845	COG2824	Alkylphosphonate utilization operon protein PhnA
JE55_RS09855	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JE55_RS09950	COG1704	LemA family
JE55_RS09955	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JE55_RS09975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JE55_RS09980	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JE55_RS10000	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JE55_RS10050	COG1609	Transcriptional regulator
JE55_RS10055	COG0840	transmembrane signaling receptor activity
JE55_RS10075	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JE55_RS10080	COG0583	DNA-binding transcription factor activity
JE55_RS10090	COG0596	Alpha beta hydrolase
JE55_RS10120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JE55_RS10140	COG3511	phospholipase C
JE55_RS10175	COG1999	signal sequence binding
JE55_RS10190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JE55_RS10220	COG2204	response regulator
JE55_RS10250	COG0025	NhaP-type Na H and K H
JE55_RS10255	COG2199	diguanylate cyclase activity
JE55_RS10255	COG2200	EAL domain
JE55_RS10265	COG1785	Belongs to the alkaline phosphatase family
JE55_RS10295	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JE55_RS10315	COG3012	SEC-C Motif Domain Protein
JE55_RS10325	COG0183	Belongs to the thiolase family
JE55_RS10330	COG0288	reversible hydration of carbon dioxide
JE55_RS10345	COG0488	(ABC) transporter
JE55_RS10350	COG0747	negative chemotaxis
JE55_RS10360	COG1028	Short-chain dehydrogenase reductase Sdr
JE55_RS10365	COG4221	oxidoreductase activity
JE55_RS10370	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JE55_RS10420	COG1024	Enoyl-CoA hydratase
JE55_RS10440	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JE55_RS10450	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JE55_RS10465	COG0737	Belongs to the 5'-nucleotidase family
JE55_RS10470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JE55_RS10475	COG1127	ABC transporter
JE55_RS10505	COG1686	Belongs to the peptidase S11 family
JE55_RS10515	COG2921	Belongs to the UPF0250 family
JE55_RS10520	COG0583	DNA-binding transcription factor activity
JE55_RS10560	COG0583	DNA-binding transcription factor activity
JE55_RS10565	COG1024	Enoyl-CoA hydratase
JE55_RS10565	COG1250	3-hydroxyacyl-CoA dehydrogenase
JE55_RS10570	COG1960	acyl-CoA dehydrogenase activity
JE55_RS10575	COG1960	acyl-CoA dehydrogenase activity
JE55_RS10580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JE55_RS10590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JE55_RS10600	COG4191	Histidine kinase
JE55_RS10610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JE55_RS10640	COG2960	long-chain fatty acid transporting porin activity
JE55_RS10650	COG0004	ammonium transporteR
JE55_RS10660	COG0189	ligase activity
JE55_RS10670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JE55_RS10675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JE55_RS10680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JE55_RS10685	COG0793	Belongs to the peptidase S41A family
JE55_RS10695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JE55_RS10715	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JE55_RS10725	COG1040	competence protein
JE55_RS10730	COG2226	methyltransferase
JE55_RS10745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JE55_RS10755	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JE55_RS10785	COG1612	heme a metabolic process
JE55_RS10795	COG1999	signal sequence binding
JE55_RS10805	COG0840	transmembrane signaling receptor activity
JE55_RS10830	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JE55_RS10845	COG0587	DNA-directed DNA polymerase activity
JE55_RS10855	COG2814	Major facilitator Superfamily
JE55_RS10890	COG2226	methyltransferase
JE55_RS10900	COG1960	acyl-CoA dehydrogenase activity
JE55_RS10910	COG0318	PFAM AMP-dependent synthetase and ligase
JE55_RS10955	COG0583	DNA-binding transcription factor activity
JE55_RS10960	COG2188	Transcriptional regulator
JE55_RS10965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JE55_RS10970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JE55_RS10975	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JE55_RS10975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JE55_RS10980	COG2190	(PTS) system
JE55_RS10980	COG1263	PTS System
JE55_RS10980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JE55_RS11000	COG1294	oxidase, subunit
JE55_RS11020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JE55_RS11025	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
JE55_RS11035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JE55_RS11045	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JE55_RS11050	COG0243	molybdopterin cofactor binding
JE55_RS11060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JE55_RS11070	COG0625	glutathione transferase activity
JE55_RS11080	COG0742	ribosomal rna small subunit methyltransferase
JE55_RS11090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JE55_RS11110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JE55_RS11125	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JE55_RS11140	COG1194	a g-specific adenine glycosylase
JE55_RS11165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JE55_RS11170	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JE55_RS11175	COG1137	ATPase activity
JE55_RS11190	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JE55_RS11210	COG1280	lysine exporter protein (LysE YggA)
JE55_RS11235	COG2814	Major facilitator Superfamily
JE55_RS11240	COG0629	single-stranded DNA binding
JE55_RS11315	COG0142	geranyltranstransferase activity
JE55_RS11370	COG0235	Class ii aldolase
JE55_RS11375	COG5001	Diguanylate cyclase
JE55_RS11375	COG5002	protein histidine kinase activity
JE55_RS11410	COG2204	response regulator
JE55_RS11430	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JE55_RS11440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JE55_RS11455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JE55_RS11460	COG1596	polysaccharide export
JE55_RS11495	COG0477	Major facilitator Superfamily
JE55_RS11520	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JE55_RS11525	COG0251	oxidation-reduction process
JE55_RS11535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JE55_RS11600	COG0494	nUDIX hydrolase
JE55_RS11615	COG1960	acyl-CoA dehydrogenase activity
JE55_RS11620	COG1250	3-hydroxyacyl-CoA dehydrogenase
JE55_RS11620	COG1024	Enoyl-CoA hydratase
JE55_RS11625	COG0183	Belongs to the thiolase family
JE55_RS11630	COG1024	Enoyl-CoA hydratase
JE55_RS11635	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JE55_RS11650	COG5265	(ABC) transporter
JE55_RS11660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JE55_RS11665	COG3178	'Phosphotransferase
JE55_RS11680	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JE55_RS11705	COG0204	Acyl-transferase
JE55_RS11710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JE55_RS11715	COG0751	glycine-tRNA ligase activity
JE55_RS11720	COG0752	glycyl-tRNA synthetase alpha subunit
JE55_RS11725	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JE55_RS11740	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
JE55_RS11750	COG1702	phosphate starvation-inducible protein PhoH
JE55_RS11760	COG0583	DNA-binding transcription factor activity
JE55_RS11765	COG2814	Major facilitator Superfamily
JE55_RS11770	COG1396	sequence-specific DNA binding
JE55_RS11780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JE55_RS11795	COG0367	asparagine synthase
JE55_RS11800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JE55_RS11805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JE55_RS11815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JE55_RS11820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JE55_RS11860	COG0513	Belongs to the DEAD box helicase family
JE55_RS11880	COG4948	Mandelate Racemase Muconate Lactonizing
JE55_RS11920	COG0840	transmembrane signaling receptor activity
JE55_RS11940	COG0583	DNA-binding transcription factor activity
JE55_RS11945	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
JE55_RS12020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JE55_RS12025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JE55_RS12030	COG0028	Belongs to the TPP enzyme family
JE55_RS12070	COG0583	DNA-binding transcription factor activity
JE55_RS12075	COG5002	protein histidine kinase activity
JE55_RS12075	COG0784	Response regulator, receiver
JE55_RS12130	COG2801	Transposase and inactivated derivatives
JE55_RS12165	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JE55_RS12170	COG2137	regulation of response to DNA damage stimulus
JE55_RS12185	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JE55_RS12190	COG0861	Integral membrane protein TerC family
JE55_RS12195	COG4969	Belongs to the N-Me-Phe pilin family
JE55_RS12200	COG3307	-O-antigen
JE55_RS12225	COG4783	chaperone-mediated protein folding
JE55_RS12235	COG0429	hydrolase of the alpha beta-hydrolase fold
JE55_RS12245	COG0859	PFAM glycosyl transferase family 9
JE55_RS12270	COG0126	phosphoglycerate kinase activity
JE55_RS12275	COG0469	pyruvate kinase activity
JE55_RS12285	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JE55_RS12290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JE55_RS12295	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JE55_RS12300	COG0009	L-threonylcarbamoyladenylate synthase
JE55_RS12335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JE55_RS12360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JE55_RS12365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JE55_RS12380	COG2233	PERMEase
JE55_RS12385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JE55_RS12400	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JE55_RS12405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JE55_RS12410	COG1121	(ABC) transporter
JE55_RS12420	COG0735	belongs to the Fur family
JE55_RS12430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JE55_RS12445	COG1175	transmembrane transport
JE55_RS12455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JE55_RS12460	COG3842	ATPase activity
JE55_RS12470	COG0583	DNA-binding transcription factor activity
JE55_RS12485	COG2390	Transcriptional regulator
JE55_RS12490	COG1070	Carbohydrate kinase
JE55_RS12495	COG0246	Mannitol dehydrogenase
JE55_RS12500	COG0583	DNA-binding transcription factor activity
JE55_RS12510	COG1012	belongs to the aldehyde dehydrogenase family
JE55_RS12515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JE55_RS12545	COG1522	sequence-specific DNA binding
JE55_RS12550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JE55_RS12560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JE55_RS12575	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JE55_RS12585	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JE55_RS12590	COG3118	belongs to the thioredoxin family
JE55_RS12595	COG1741	Belongs to the pirin family
JE55_RS12605	COG0860	N-Acetylmuramoyl-L-alanine amidase
JE55_RS12610	COG0802	atpase or kinase
JE55_RS12615	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JE55_RS12625	COG4974	Belongs to the 'phage' integrase family
JE55_RS12630	COG0318	PFAM AMP-dependent synthetase and ligase
JE55_RS12635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JE55_RS12650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JE55_RS12655	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JE55_RS12670	COG0728	peptidoglycan biosynthetic process
JE55_RS12700	COG1663	tetraacyldisaccharide 4'-kinase activity
JE55_RS12705	COG1570	exodeoxyribonuclease VII activity
JE55_RS12710	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JE55_RS12755	COG2814	Major facilitator Superfamily
JE55_RS12775	COG2188	Transcriptional regulator
JE55_RS12780	COG0656	L-ascorbic acid biosynthetic process
JE55_RS12800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JE55_RS12825	COG1278	Cold shock
JE55_RS12835	COG0542	response to heat
JE55_RS12840	COG1113	amino acid transport
JE55_RS12870	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JE55_RS12875	COG0196	riboflavin kinase activity
JE55_RS12880	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JE55_RS12885	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JE55_RS12885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JE55_RS12890	COG1511	domain protein
JE55_RS12890	COG3264	Mechanosensitive ion channel
JE55_RS12915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JE55_RS12935	COG1047	Peptidyl-prolyl cis-trans
JE55_RS12940	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JE55_RS12975	COG0456	acetyltransferase
JE55_RS12980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JE55_RS12985	COG0543	2 iron, 2 sulfur cluster binding
JE55_RS12985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JE55_RS13000	COG1187	pseudouridine synthase activity
JE55_RS13010	COG0583	DNA-binding transcription factor activity
JE55_RS13020	COG2267	carboxylic ester hydrolase activity
JE55_RS13025	COG2258	MOSC domain
JE55_RS13030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JE55_RS13040	COG1396	sequence-specific DNA binding
JE55_RS13060	COG0583	DNA-binding transcription factor activity
JE55_RS13075	COG0175	sulfate reduction
JE55_RS13085	COG2895	sulfate adenylyltransferase (ATP) activity
JE55_RS13090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JE55_RS13090	COG1648	precorrin-2 dehydrogenase activity
JE55_RS13110	COG0795	lipopolysaccharide-transporting ATPase activity
JE55_RS13130	COG4654	Cytochrome c, class I
JE55_RS13140	COG0583	DNA-binding transcription factor activity
JE55_RS13170	COG4206	TonB-dependent receptor
JE55_RS13180	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JE55_RS13185	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JE55_RS13190	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JE55_RS13205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JE55_RS13215	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JE55_RS13225	COG1492	cobalamin metabolic process
JE55_RS13230	COG2259	Doxx family
JE55_RS13235	COG0489	protein tyrosine kinase activity
JE55_RS13250	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JE55_RS13260	COG0729	surface antigen
JE55_RS13265	COG2911	Protein conserved in bacteria
JE55_RS13285	COG2885	chlorophyll binding
JE55_RS13285	COG3047	cAMP biosynthetic process
JE55_RS13290	COG0489	protein tyrosine kinase activity
JE55_RS13315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JE55_RS13350	COG2226	methyltransferase
JE55_RS13385	COG2271	Major facilitator Superfamily
JE55_RS13400	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JE55_RS13405	COG2827	Endonuclease containing a URI domain
JE55_RS13410	COG1472	Belongs to the glycosyl hydrolase 3 family
JE55_RS13425	COG0347	Belongs to the P(II) protein family
JE55_RS13445	COG4215	(ABC) transporter
JE55_RS13460	COG1741	Belongs to the pirin family
JE55_RS13485	COG1176	ABC-type spermidine putrescine transport system, permease component I
JE55_RS13490	COG1116	anion transmembrane transporter activity
JE55_RS13510	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JE55_RS13525	COG2814	Major facilitator Superfamily
JE55_RS13530	COG1881	PFAM PEBP family protein
JE55_RS13640	COG1773	rubredoxin
JE55_RS13650	COG0488	(ABC) transporter
JE55_RS13675	COG0583	DNA-binding transcription factor activity
JE55_RS13685	COG0583	DNA-binding transcription factor activity
JE55_RS13690	COG0477	Major facilitator Superfamily
JE55_RS13730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JE55_RS13735	COG0697	spore germination
JE55_RS13745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JE55_RS13765	COG4106	trans-aconitate 2-methyltransferase activity
JE55_RS13780	COG2764	glyoxalase bleomycin resistance protein dioxygenase
JE55_RS13790	COG3135	benzoate transporter
JE55_RS13825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JE55_RS13830	COG2878	Part of a membrane complex involved in electron transport
JE55_RS13835	COG1309	transcriptional regulator
JE55_RS13845	COG3387	PFAM Glycoside hydrolase 15-related
JE55_RS13850	COG2706	6-phosphogluconolactonase activity
JE55_RS13855	COG1674	ftsk spoiiie
JE55_RS13885	COG0513	Belongs to the DEAD box helicase family
JE55_RS13890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JE55_RS13930	COG0438	transferase activity, transferring glycosyl groups
JE55_RS13935	COG0859	PFAM glycosyl transferase family 9
JE55_RS13965	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JE55_RS13970	COG1595	DNA-templated transcription, initiation
JE55_RS14010	COG2233	PERMEase
JE55_RS14130	COG0799	negative regulation of ribosome biogenesis
JE55_RS14145	COG0151	Belongs to the GarS family
JE55_RS14160	COG1028	Short-chain dehydrogenase reductase Sdr
JE55_RS14180	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JE55_RS14185	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JE55_RS14200	COG2205	protein histidine kinase activity
JE55_RS14205	COG0745	RESPONSE REGULATOR receiver
JE55_RS14235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JE55_RS14245	COG0154	amidase activity
JE55_RS14255	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JE55_RS14260	COG1028	Short-chain dehydrogenase reductase Sdr
JE55_RS14280	COG0438	transferase activity, transferring glycosyl groups
JE55_RS14310	COG0028	Belongs to the TPP enzyme family
JE55_RS14330	COG1183	phosphatidylcholine synthase activity
JE55_RS14340	COG0659	secondary active sulfate transmembrane transporter activity
JE55_RS14345	COG0288	reversible hydration of carbon dioxide
JE55_RS14360	COG0683	leucine binding
JE55_RS14375	COG4221	oxidoreductase activity
JE55_RS14375	COG0604	alcohol dehydrogenase
JE55_RS14375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JE55_RS14375	COG3321	synthase
JE55_RS14380	COG0149	triose-phosphate isomerase activity
JE55_RS14415	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
JE55_RS14425	COG1034	ATP synthesis coupled electron transport
JE55_RS14460	COG1007	ATP synthesis coupled electron transport
JE55_RS14480	COG1960	acyl-CoA dehydrogenase activity
JE55_RS14485	COG1960	acyl-CoA dehydrogenase activity
JE55_RS14490	COG1012	belongs to the aldehyde dehydrogenase family
JE55_RS14490	COG2030	dehydratase
JE55_RS14510	COG1960	acyl-CoA dehydrogenase activity
JE55_RS14520	COG0588	phosphoglycerate mutase activity
JE55_RS14525	COG1024	Enoyl-CoA hydratase
JE55_RS14535	COG0436	Aminotransferase
JE55_RS14550	COG2866	Carboxypeptidase
JE55_RS14600	COG0006	proline dipeptidase activity
JE55_RS14615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JE55_RS14625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JE55_RS14645	COG2863	cytochrome
JE55_RS14650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JE55_RS14650	COG2010	Cytochrome c
JE55_RS14665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JE55_RS14700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JE55_RS14705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JE55_RS14730	COG1959	2 iron, 2 sulfur cluster binding
JE55_RS14745	COG1522	sequence-specific DNA binding
JE55_RS14750	COG3842	ATPase activity
JE55_RS14755	COG1176	ABC-type spermidine putrescine transport system, permease component I
JE55_RS14760	COG1840	ABC-type Fe3 transport system, periplasmic component
JE55_RS14775	COG1289	transmembrane transporter activity
JE55_RS14785	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JE55_RS14790	COG1074	ATP-dependent DNA helicase activity
JE55_RS14795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JE55_RS14805	COG2200	EAL domain
JE55_RS14850	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
JE55_RS14855	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JE55_RS14865	COG0697	spore germination
JE55_RS14870	COG2814	Major facilitator Superfamily
JE55_RS14890	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JE55_RS14895	COG3842	ATPase activity
JE55_RS14900	COG1177	transmembrane transport
JE55_RS14915	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JE55_RS14920	COG1840	ABC-type Fe3 transport system, periplasmic component
JE55_RS14925	COG1609	Transcriptional regulator
JE55_RS14965	COG2188	Transcriptional regulator
JE55_RS14970	COG1522	sequence-specific DNA binding
JE55_RS14990	COG0583	DNA-binding transcription factor activity
JE55_RS15020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JE55_RS15055	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JE55_RS15060	COG1250	3-hydroxyacyl-CoA dehydrogenase
JE55_RS15065	COG0583	DNA-binding transcription factor activity
JE55_RS15090	COG3052	prosthetic group binding
JE55_RS15110	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
JE55_RS15120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JE55_RS15145	COG0477	Major facilitator Superfamily
JE55_RS15155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JE55_RS15160	COG0328	RNA-DNA hybrid ribonuclease activity
JE55_RS15165	COG2226	methyltransferase
JE55_RS15170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JE55_RS15175	COG0741	lytic transglycosylase activity
JE55_RS15175	COG1388	LysM domain
JE55_RS15195	COG0505	Belongs to the CarA family
JE55_RS15205	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JE55_RS15210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JE55_RS15220	COG1534	Rna-binding protein
JE55_RS15230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JE55_RS15235	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JE55_RS15245	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JE55_RS15250	COG0573	inorganic phosphate transmembrane transporter activity
JE55_RS15255	COG0581	inorganic phosphate transmembrane transporter activity
JE55_RS15270	COG0745	RESPONSE REGULATOR receiver
JE55_RS15280	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JE55_RS15350	COG0534	Mate efflux family protein
JE55_RS15360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JE55_RS15365	COG4942	peptidase
JE55_RS15390	COG0582	viral genome integration into host DNA
JE55_RS15420	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JE55_RS15465	COG0366	Alpha amylase catalytic
JE55_RS15470	COG0366	Alpha amylase catalytic
JE55_RS15505	COG0583	DNA-binding transcription factor activity
JE55_RS15510	COG0745	RESPONSE REGULATOR receiver
JE55_RS15555	COG0457	Tetratricopeptide repeat
JE55_RS15555	COG0859	PFAM glycosyl transferase family 9
JE55_RS15720	COG2814	Major facilitator Superfamily
JE55_RS15725	COG0583	DNA-binding transcription factor activity
JE55_RS15765	COG2197	response regulator
JE55_RS15770	COG1538	Outer membrane efflux protein
JE55_RS15775	COG2814	Major facilitator Superfamily
JE55_RS15780	COG1566	PFAM secretion protein HlyD family protein
JE55_RS15795	COG3511	phospholipase C
JE55_RS15800	COG1858	cytochrome C peroxidase
JE55_RS15820	COG1051	belongs to the nudix hydrolase family
JE55_RS15825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JE55_RS15835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JE55_RS15850	COG0477	Major facilitator Superfamily
JE55_RS15855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JE55_RS15865	COG2816	NAD+ diphosphatase activity
JE55_RS15880	COG0824	Thioesterase
JE55_RS15890	COG0411	ABC transporter
JE55_RS15900	COG3718	enzyme involved in inositol metabolism
JE55_RS15910	COG3962	Belongs to the TPP enzyme family
JE55_RS15925	COG1172	Belongs to the binding-protein-dependent transport system permease family
JE55_RS15940	COG0673	inositol 2-dehydrogenase activity
JE55_RS15945	COG0673	inositol 2-dehydrogenase activity
JE55_RS15950	COG0425	Belongs to the sulfur carrier protein TusA family
JE55_RS15960	COG0745	RESPONSE REGULATOR receiver
JE55_RS15970	COG5002	protein histidine kinase activity
JE55_RS15980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JE55_RS15985	COG0525	valine-tRNA ligase activity
JE55_RS15990	COG0210	DNA helicase
JE55_RS15995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JE55_RS16000	COG2223	nitrite transmembrane transporter activity
JE55_RS16005	COG0840	transmembrane signaling receptor activity
JE55_RS16035	COG0583	DNA-binding transcription factor activity
JE55_RS16050	COG0277	FAD linked oxidase domain protein
JE55_RS16065	COG1295	ribonuclease BN
JE55_RS16080	COG0477	Major facilitator Superfamily
JE55_RS16105	COG1028	Short-chain dehydrogenase reductase Sdr
JE55_RS16140	COG1028	Short-chain dehydrogenase reductase Sdr
JE55_RS16155	COG0583	DNA-binding transcription factor activity
JE55_RS16165	COG2267	carboxylic ester hydrolase activity
JE55_RS16170	COG0251	oxidation-reduction process
JE55_RS16175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JE55_RS16190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JE55_RS16215	COG0776	regulation of translation
JE55_RS16230	COG2755	lipolytic protein G-D-S-L family
JE55_RS16230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JE55_RS16250	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
JE55_RS16290	COG0583	DNA-binding transcription factor activity
JE55_RS16295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JE55_RS16300	COG1187	pseudouridine synthase activity
JE55_RS16310	COG2251	uridine kinase activity
JE55_RS16310	COG0195	Participates in both transcription termination and antitermination
JE55_RS16325	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JE55_RS16330	COG2814	Major facilitator Superfamily
JE55_RS16335	COG1566	PFAM secretion protein HlyD family protein
JE55_RS16345	COG1846	Transcriptional regulator
JE55_RS16350	COG1217	gtp-binding protein TYPA
JE55_RS16365	COG0567	Dehydrogenase, E1 component
JE55_RS16370	COG0508	dehydrogenase complex catalyzes the overall conversion of
JE55_RS16375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JE55_RS16380	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JE55_RS16435	COG4964	Belongs to the GSP D family
JE55_RS16500	COG0318	PFAM AMP-dependent synthetase and ligase
JE55_RS16510	COG2814	Major facilitator Superfamily
JE55_RS16515	COG0519	Catalyzes the synthesis of GMP from XMP
JE55_RS16540	COG0840	transmembrane signaling receptor activity
JE55_RS16555	COG0557	exoribonuclease II activity
JE55_RS16560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JE55_RS16570	COG3023	N-Acetylmuramoyl-L-alanine amidase
JE55_RS16580	COG1802	Transcriptional regulator
JE55_RS16585	COG0673	inositol 2-dehydrogenase activity
JE55_RS16590	COG0765	amino acid transport
JE55_RS16595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JE55_RS16650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JE55_RS16690	COG1301	dicarboxylic acid transport
JE55_RS16710	COG0667	Aldo Keto reductase
JE55_RS16715	COG0701	Predicted permease
JE55_RS16755	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JE55_RS16760	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JE55_RS16765	COG4208	sulfate ABC transporter
JE55_RS16770	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JE55_RS16775	COG0583	DNA-binding transcription factor activity
JE55_RS16780	COG1879	ABC-type sugar transport system periplasmic component
JE55_RS16785	COG1129	ABC transporter
JE55_RS16790	COG1172	Belongs to the binding-protein-dependent transport system permease family
JE55_RS16795	COG1609	Transcriptional regulator
JE55_RS16800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JE55_RS16805	COG0840	transmembrane signaling receptor activity
JE55_RS16810	COG2766	serine protein kinase
JE55_RS16815	COG2718	Belongs to the UPF0229 family
JE55_RS16820	COG2719	SpoVR family
JE55_RS16825	COG0477	Major facilitator Superfamily
JE55_RS16840	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JE55_RS16845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JE55_RS16865	COG4964	Belongs to the GSP D family
JE55_RS16910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JE55_RS16920	COG4597	amino acid ABC transporter
JE55_RS16925	COG0765	amino acid transport
JE55_RS16930	COG0739	heme binding
JE55_RS16935	COG1309	transcriptional regulator
JE55_RS16945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JE55_RS16960	COG3539	Fimbrial protein
JE55_RS16970	COG3121	Chaperone
JE55_RS16980	COG1132	(ABC) transporter
JE55_RS16980	COG2375	cellular response to nickel ion
JE55_RS17000	COG1879	ABC-type sugar transport system periplasmic component
JE55_RS17010	COG1172	Belongs to the binding-protein-dependent transport system permease family
JE55_RS17015	COG1063	alcohol dehydrogenase
JE55_RS17020	COG1070	Carbohydrate kinase
JE55_RS17025	COG1028	Short-chain dehydrogenase reductase Sdr
JE55_RS17050	COG1120	ATPase activity
JE55_RS17095	COG3486	L-lysine 6-monooxygenase (NADPH) activity
JE55_RS17100	COG4774	siderophore transport
JE55_RS17105	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JE55_RS17135	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JE55_RS17165	COG0400	carboxylic ester hydrolase activity
JE55_RS17175	COG3979	chitinase
JE55_RS17195	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JE55_RS17205	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
JE55_RS17225	COG1649	PFAM Uncharacterised BCR, COG1649
JE55_RS17230	COG2807	transmembrane transport
JE55_RS17235	COG1846	Transcriptional regulator
JE55_RS17250	COG0625	glutathione transferase activity
JE55_RS17255	COG0583	DNA-binding transcription factor activity
JE55_RS17275	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JE55_RS17280	COG2235	arginine
JE55_RS17295	COG1174	glycine betaine transport
JE55_RS17300	COG1125	glycine betaine transport
JE55_RS17305	COG1174	glycine betaine transport
JE55_RS17310	COG1732	Glycine betaine
JE55_RS17320	COG0477	Major facilitator Superfamily
JE55_RS17325	COG0318	PFAM AMP-dependent synthetase and ligase
JE55_RS17345	COG0835	chemotaxis
JE55_RS17350	COG0697	spore germination
JE55_RS17355	COG2207	Transcriptional regulator
JE55_RS17360	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JE55_RS17375	COG3251	PFAM MbtH domain protein
JE55_RS17385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JE55_RS17400	COG0137	argininosuccinate synthase activity
JE55_RS17405	COG0165	Argininosuccinate lyase
JE55_RS17425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JE55_RS17450	COG2192	nodulation
JE55_RS17475	COG3220	belongs to the UPF0276 family
JE55_RS17495	COG4944	Protein of unknown function (DUF1109)
JE55_RS17500	COG1595	DNA-templated transcription, initiation
JE55_RS17515	COG3436	PFAM IS66 Orf2 family protein
JE55_RS17520	COG2801	Transposase and inactivated derivatives
JE55_RS17525	COG2963	transposase activity
JE55_RS17555	COG0745	RESPONSE REGULATOR receiver
JE55_RS17560	COG0529	Catalyzes the synthesis of activated sulfate
JE55_RS17570	COG0859	PFAM glycosyl transferase family 9
JE55_RS17570	COG0457	Tetratricopeptide repeat
JE55_RS17580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JE55_RS17585	COG2274	protein secretion by the type I secretion system
JE55_RS17615	COG2916	Histone family protein nucleoid-structuring protein H-NS
JE55_RS17625	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JE55_RS17640	COG3842	ATPase activity
JE55_RS17650	COG1176	ABC-type spermidine putrescine transport system, permease component I
JE55_RS17665	COG1012	belongs to the aldehyde dehydrogenase family
JE55_RS17670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JE55_RS17715	COG3328	transposase activity
JE55_RS17745	COG2197	response regulator
JE55_RS17760	COG5295	Hep Hag repeat protein
JE55_RS17795	COG3121	Chaperone
JE55_RS17855	COG0475	glutathione-regulated potassium exporter activity
JE55_RS17875	COG2376	Dihydroxyacetone kinase
JE55_RS17885	COG0840	transmembrane signaling receptor activity
JE55_RS17910	COG4263	nitrous-oxide reductase activity
JE55_RS17925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JE55_RS17955	COG3264	Mechanosensitive ion channel
JE55_RS17955	COG1196	nuclear chromosome segregation
JE55_RS17985	COG0598	Magnesium transport protein CorA
JE55_RS18065	COG1609	Transcriptional regulator
JE55_RS18070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JE55_RS18080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JE55_RS18100	COG2855	membrane
JE55_RS18105	COG0038	chloride channel
JE55_RS18120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JE55_RS18125	COG1538	Outer membrane efflux protein
JE55_RS18145	COG3655	Transcriptional regulator
JE55_RS18170	COG0730	response to heat
JE55_RS18170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JE55_RS18175	COG1177	transmembrane transport
JE55_RS18180	COG1176	ABC-type spermidine putrescine transport system, permease component I
JE55_RS18185	COG3842	ATPase activity
JE55_RS18190	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JE55_RS18195	COG1914	H( )-stimulated, divalent metal cation uptake system
JE55_RS18205	COG3047	cAMP biosynthetic process
JE55_RS18210	COG2070	2-Nitropropane dioxygenase
JE55_RS18225	COG0488	(ABC) transporter
JE55_RS18235	COG2982	Protein involved in outer membrane biogenesis
JE55_RS18240	COG1122	ATPase activity
JE55_RS18245	COG0390	transport system, permease component
JE55_RS18555	COG0542	response to heat
JE55_RS18795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JE55_RS18795	COG0047	phosphoribosylformylglycinamidine synthase activity
JE55_RS18810	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JE55_RS18810	COG0047	phosphoribosylformylglycinamidine synthase activity
JE55_RS19485	COG0477	Major facilitator Superfamily
JE55_RS19525	COG2224	Isocitrate lyase
JE55_RS19700	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JE55_RS19760	COG4221	oxidoreductase activity
JE55_RS19760	COG3321	synthase
JE55_RS19760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JE55_RS19760	COG1028	Short-chain dehydrogenase reductase Sdr
JE55_RS19825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JE55_RS19880	COG0037	tRNA processing
JE55_RS20240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JE55_RS20375	COG0339	signal peptide processing
JE55_RS20395	COG2223	nitrite transmembrane transporter activity
JE55_RS20460	COG2204	response regulator
JE55_RS20540	COG1960	acyl-CoA dehydrogenase activity
JE55_RS20700	COG0826	peptidase U32
JE55_RS20895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JE55_RS21405	COG0114	fumarate hydratase activity
JE55_RS21750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JE55_RS21875	COG0322	excinuclease ABC activity
JE55_RS21935	COG0477	Major facilitator Superfamily
JE55_RS22050	COG1737	Transcriptional regulator
JE55_RS22050	COG0837	glucose binding
JE55_RS22845	COG0156	8-amino-7-oxononanoate synthase activity
JE55_RS22855	COG1028	Short-chain dehydrogenase reductase Sdr
JE55_RS22855	COG0604	alcohol dehydrogenase
JE55_RS22855	COG3321	synthase
JE55_RS23120	COG0497	DNA recombination
JE55_RS23125	COG0497	DNA recombination
JE55_RS23175	COG0312	modulator of DNA gyrase
JE55_RS23265	COG3626	phosphonate metabolism
JE55_RS23310	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JE55_RS23795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JE55_RS23870	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JE55_RS23870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JE55_RS24665	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JE55_RS25290	COG1002	Type II restriction enzyme, methylase subunits
JE55_RS26355	COG1250	3-hydroxyacyl-CoA dehydrogenase
JE55_RS26355	COG1024	Enoyl-CoA hydratase
JE55_RS26490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JE55_RS26535	COG0583	DNA-binding transcription factor activity
JE55_RS27020	COG4608	Belongs to the ABC transporter superfamily
JE55_RS27050	COG1984	allophanate hydrolase subunit 2
JE55_RS27130	COG1706	bacterial-type flagellum-dependent cell motility
JE55_RS27170	COG2233	PERMEase
JE55_RS27595	COG0025	NhaP-type Na H and K H
JE55_RS27750	COG1410	methionine synthase
JE55_RS27750	COG0646	methionine synthase
JE55_RS28080	COG1999	signal sequence binding
JE55_RS28130	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JE55_RS28155	COG0587	DNA-directed DNA polymerase activity
JE55_RS28515	COG3447	MASE1 domain protein
JE55_RS28515	COG5001	Diguanylate cyclase
JE55_RS28515	COG5002	protein histidine kinase activity
JE55_RS29010	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JE55_RS29075	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
JE55_RS29335	COG0126	phosphoglycerate kinase activity
JE55_RS29355	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JE55_RS29500	COG1175	transmembrane transport
JE55_RS29925	COG1136	(ABC) transporter
JE55_RS30140	COG0489	protein tyrosine kinase activity
JE55_RS30160	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JE55_RS30445	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JE55_RS30760	COG2706	6-phosphogluconolactonase activity
JE55_RS31205	COG0028	Belongs to the TPP enzyme family
JE55_RS31410	COG2866	Carboxypeptidase
JE55_RS31565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JE55_RS31580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JE55_RS31720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JE55_RS31870	COG0477	Major facilitator Superfamily
JE55_RS32250	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JE55_RS32250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source