locus-tag	class	description
DR55_RS00025	COG1595	DNA-templated transcription, initiation
DR55_RS00030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DR55_RS00060	COG0859	PFAM glycosyl transferase family 9
DR55_RS00065	COG0438	transferase activity, transferring glycosyl groups
DR55_RS00105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DR55_RS00110	COG0513	Belongs to the DEAD box helicase family
DR55_RS00140	COG1674	ftsk spoiiie
DR55_RS00145	COG2706	6-phosphogluconolactonase activity
DR55_RS00150	COG3387	PFAM Glycoside hydrolase 15-related
DR55_RS00160	COG1309	transcriptional regulator
DR55_RS00165	COG2878	Part of a membrane complex involved in electron transport
DR55_RS00170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DR55_RS00205	COG3135	benzoate transporter
DR55_RS00220	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DR55_RS00235	COG4106	trans-aconitate 2-methyltransferase activity
DR55_RS00255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DR55_RS00265	COG0697	spore germination
DR55_RS00270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DR55_RS00305	COG0477	Major facilitator Superfamily
DR55_RS00310	COG0583	DNA-binding transcription factor activity
DR55_RS00320	COG0583	DNA-binding transcription factor activity
DR55_RS00340	COG0488	(ABC) transporter
DR55_RS00350	COG1773	rubredoxin
DR55_RS00440	COG1881	PFAM PEBP family protein
DR55_RS00445	COG2814	Major facilitator Superfamily
DR55_RS00465	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DR55_RS00485	COG1116	anion transmembrane transporter activity
DR55_RS00490	COG1176	ABC-type spermidine putrescine transport system, permease component I
DR55_RS00515	COG1741	Belongs to the pirin family
DR55_RS00530	COG4215	(ABC) transporter
DR55_RS00550	COG0347	Belongs to the P(II) protein family
DR55_RS00570	COG2827	Endonuclease containing a URI domain
DR55_RS00575	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DR55_RS00590	COG2271	Major facilitator Superfamily
DR55_RS00620	COG2226	methyltransferase
DR55_RS00655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DR55_RS00680	COG0489	protein tyrosine kinase activity
DR55_RS00685	COG2885	chlorophyll binding
DR55_RS00685	COG3047	cAMP biosynthetic process
DR55_RS00705	COG2911	Protein conserved in bacteria
DR55_RS00710	COG0729	surface antigen
DR55_RS00720	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DR55_RS00735	COG0489	protein tyrosine kinase activity
DR55_RS00740	COG2259	Doxx family
DR55_RS00745	COG1492	cobalamin metabolic process
DR55_RS00755	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DR55_RS00765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DR55_RS00780	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DR55_RS00785	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DR55_RS00790	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DR55_RS00800	COG4206	TonB-dependent receptor
DR55_RS00830	COG0583	DNA-binding transcription factor activity
DR55_RS00840	COG4654	Cytochrome c, class I
DR55_RS00860	COG0795	lipopolysaccharide-transporting ATPase activity
DR55_RS00875	COG1648	precorrin-2 dehydrogenase activity
DR55_RS00875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DR55_RS00880	COG2895	sulfate adenylyltransferase (ATP) activity
DR55_RS00890	COG0175	sulfate reduction
DR55_RS00905	COG0583	DNA-binding transcription factor activity
DR55_RS00920	COG1396	sequence-specific DNA binding
DR55_RS00930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DR55_RS00935	COG2258	MOSC domain
DR55_RS00940	COG2267	carboxylic ester hydrolase activity
DR55_RS00950	COG0583	DNA-binding transcription factor activity
DR55_RS00960	COG1187	pseudouridine synthase activity
DR55_RS00975	COG0543	2 iron, 2 sulfur cluster binding
DR55_RS00975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DR55_RS00980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DR55_RS00985	COG0456	acetyltransferase
DR55_RS01020	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DR55_RS01025	COG1047	Peptidyl-prolyl cis-trans
DR55_RS01045	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DR55_RS01065	COG1511	domain protein
DR55_RS01065	COG3264	Mechanosensitive ion channel
DR55_RS01070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DR55_RS01070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DR55_RS01075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DR55_RS01080	COG0196	riboflavin kinase activity
DR55_RS01085	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DR55_RS01115	COG1113	amino acid transport
DR55_RS01120	COG0542	response to heat
DR55_RS01130	COG1278	Cold shock
DR55_RS01135	COG2132	Multicopper oxidase
DR55_RS01155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DR55_RS01175	COG0656	L-ascorbic acid biosynthetic process
DR55_RS01180	COG2188	Transcriptional regulator
DR55_RS01195	COG2814	Major facilitator Superfamily
DR55_RS01240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DR55_RS01245	COG1570	exodeoxyribonuclease VII activity
DR55_RS01250	COG1663	tetraacyldisaccharide 4'-kinase activity
DR55_RS01280	COG0728	peptidoglycan biosynthetic process
DR55_RS01295	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DR55_RS01300	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DR55_RS01315	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DR55_RS01320	COG0318	PFAM AMP-dependent synthetase and ligase
DR55_RS01325	COG4974	Belongs to the 'phage' integrase family
DR55_RS01335	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DR55_RS01340	COG0802	atpase or kinase
DR55_RS01345	COG0860	N-Acetylmuramoyl-L-alanine amidase
DR55_RS01355	COG1741	Belongs to the pirin family
DR55_RS01360	COG3118	belongs to the thioredoxin family
DR55_RS01365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DR55_RS01375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DR55_RS01390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DR55_RS01400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DR55_RS01405	COG1522	sequence-specific DNA binding
DR55_RS01425	COG2271	Major facilitator Superfamily
DR55_RS01435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DR55_RS01440	COG1012	belongs to the aldehyde dehydrogenase family
DR55_RS01450	COG0583	DNA-binding transcription factor activity
DR55_RS01455	COG0246	Mannitol dehydrogenase
DR55_RS01460	COG1070	Carbohydrate kinase
DR55_RS01465	COG2390	Transcriptional regulator
DR55_RS01480	COG0583	DNA-binding transcription factor activity
DR55_RS01490	COG3842	ATPase activity
DR55_RS01495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DR55_RS01505	COG1175	transmembrane transport
DR55_RS01520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DR55_RS01530	COG0735	belongs to the Fur family
DR55_RS01540	COG1121	(ABC) transporter
DR55_RS01545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DR55_RS01550	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DR55_RS01565	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DR55_RS01570	COG2233	PERMEase
DR55_RS01580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DR55_RS01585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DR55_RS01610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DR55_RS01645	COG0009	L-threonylcarbamoyladenylate synthase
DR55_RS01650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DR55_RS01655	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DR55_RS01660	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DR55_RS01670	COG0469	pyruvate kinase activity
DR55_RS01675	COG0126	phosphoglycerate kinase activity
DR55_RS01700	COG0859	PFAM glycosyl transferase family 9
DR55_RS01710	COG0429	hydrolase of the alpha beta-hydrolase fold
DR55_RS01720	COG4783	chaperone-mediated protein folding
DR55_RS01740	COG3307	-O-antigen
DR55_RS01745	COG4969	Belongs to the N-Me-Phe pilin family
DR55_RS01750	COG0861	Integral membrane protein TerC family
DR55_RS01755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DR55_RS01770	COG2137	regulation of response to DNA damage stimulus
DR55_RS01775	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DR55_RS01810	COG2801	Transposase and inactivated derivatives
DR55_RS01860	COG0784	Response regulator, receiver
DR55_RS01860	COG5002	protein histidine kinase activity
DR55_RS01865	COG0583	DNA-binding transcription factor activity
DR55_RS01900	COG0028	Belongs to the TPP enzyme family
DR55_RS01905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DR55_RS01910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DR55_RS01980	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DR55_RS01985	COG0583	DNA-binding transcription factor activity
DR55_RS02005	COG0840	transmembrane signaling receptor activity
DR55_RS02045	COG4948	Mandelate Racemase Muconate Lactonizing
DR55_RS02065	COG0513	Belongs to the DEAD box helicase family
DR55_RS02105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DR55_RS02110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DR55_RS02120	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DR55_RS02125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DR55_RS02130	COG0367	asparagine synthase
DR55_RS02145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DR55_RS02155	COG1396	sequence-specific DNA binding
DR55_RS02160	COG2814	Major facilitator Superfamily
DR55_RS02165	COG0583	DNA-binding transcription factor activity
DR55_RS02175	COG1702	phosphate starvation-inducible protein PhoH
DR55_RS02185	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DR55_RS02195	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DR55_RS02200	COG0752	glycyl-tRNA synthetase alpha subunit
DR55_RS02205	COG0751	glycine-tRNA ligase activity
DR55_RS02210	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DR55_RS02215	COG0204	Acyl-transferase
DR55_RS02240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DR55_RS02255	COG3178	'Phosphotransferase
DR55_RS02260	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DR55_RS02270	COG5265	(ABC) transporter
DR55_RS02285	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DR55_RS02290	COG1024	Enoyl-CoA hydratase
DR55_RS02295	COG0183	Belongs to the thiolase family
DR55_RS02300	COG1250	3-hydroxyacyl-CoA dehydrogenase
DR55_RS02300	COG1024	Enoyl-CoA hydratase
DR55_RS02305	COG1960	acyl-CoA dehydrogenase activity
DR55_RS02320	COG0494	nUDIX hydrolase
DR55_RS02385	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DR55_RS02395	COG0251	oxidation-reduction process
DR55_RS02405	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DR55_RS02430	COG0477	Major facilitator Superfamily
DR55_RS02460	COG1596	polysaccharide export
DR55_RS02465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DR55_RS02480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DR55_RS02490	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DR55_RS02510	COG2204	response regulator
DR55_RS02545	COG5002	protein histidine kinase activity
DR55_RS02545	COG5001	Diguanylate cyclase
DR55_RS02550	COG0235	Class ii aldolase
DR55_RS02645	COG1396	sequence-specific DNA binding
DR55_RS02725	COG0629	single-stranded DNA binding
DR55_RS02730	COG2814	Major facilitator Superfamily
DR55_RS02755	COG1280	lysine exporter protein (LysE YggA)
DR55_RS02775	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DR55_RS02790	COG1137	ATPase activity
DR55_RS02795	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DR55_RS02800	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DR55_RS02825	COG1194	a g-specific adenine glycosylase
DR55_RS02840	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DR55_RS02855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DR55_RS02875	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DR55_RS02885	COG0742	ribosomal rna small subunit methyltransferase
DR55_RS02895	COG0625	glutathione transferase activity
DR55_RS02905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DR55_RS02915	COG0243	molybdopterin cofactor binding
DR55_RS02920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DR55_RS02930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DR55_RS02940	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DR55_RS02945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DR55_RS02960	COG1294	oxidase, subunit
DR55_RS02980	COG2190	(PTS) system
DR55_RS02980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DR55_RS02980	COG1263	PTS System
DR55_RS02985	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DR55_RS02985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DR55_RS02990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DR55_RS02995	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DR55_RS03000	COG2188	Transcriptional regulator
DR55_RS03005	COG0583	DNA-binding transcription factor activity
DR55_RS03050	COG0318	PFAM AMP-dependent synthetase and ligase
DR55_RS03060	COG1960	acyl-CoA dehydrogenase activity
DR55_RS03070	COG2226	methyltransferase
DR55_RS03105	COG2814	Major facilitator Superfamily
DR55_RS03115	COG0587	DNA-directed DNA polymerase activity
DR55_RS03130	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DR55_RS03150	COG0840	transmembrane signaling receptor activity
DR55_RS03160	COG1999	signal sequence binding
DR55_RS03170	COG1612	heme a metabolic process
DR55_RS03200	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DR55_RS03210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DR55_RS03225	COG2226	methyltransferase
DR55_RS03230	COG1040	competence protein
DR55_RS03240	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DR55_RS03260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DR55_RS03270	COG0793	Belongs to the peptidase S41A family
DR55_RS03275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DR55_RS03280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DR55_RS03285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DR55_RS03295	COG0189	ligase activity
DR55_RS03305	COG0004	ammonium transporteR
DR55_RS03315	COG2960	long-chain fatty acid transporting porin activity
DR55_RS03350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DR55_RS03360	COG4191	Histidine kinase
DR55_RS03370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DR55_RS03380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DR55_RS03385	COG1960	acyl-CoA dehydrogenase activity
DR55_RS03390	COG1960	acyl-CoA dehydrogenase activity
DR55_RS03395	COG1250	3-hydroxyacyl-CoA dehydrogenase
DR55_RS03395	COG1024	Enoyl-CoA hydratase
DR55_RS03400	COG0583	DNA-binding transcription factor activity
DR55_RS03445	COG0583	DNA-binding transcription factor activity
DR55_RS03450	COG2921	Belongs to the UPF0250 family
DR55_RS03460	COG1686	Belongs to the peptidase S11 family
DR55_RS03495	COG1127	ABC transporter
DR55_RS03500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DR55_RS03505	COG0737	Belongs to the 5'-nucleotidase family
DR55_RS03520	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DR55_RS03530	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DR55_RS03550	COG1024	Enoyl-CoA hydratase
DR55_RS03600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DR55_RS03605	COG4221	oxidoreductase activity
DR55_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
DR55_RS03625	COG0747	negative chemotaxis
DR55_RS03630	COG0488	(ABC) transporter
DR55_RS03645	COG0288	reversible hydration of carbon dioxide
DR55_RS03650	COG0183	Belongs to the thiolase family
DR55_RS03660	COG3012	SEC-C Motif Domain Protein
DR55_RS03705	COG1785	Belongs to the alkaline phosphatase family
DR55_RS03715	COG2199	diguanylate cyclase activity
DR55_RS03715	COG2200	EAL domain
DR55_RS03720	COG0025	NhaP-type Na H and K H
DR55_RS03755	COG4650	regulator
DR55_RS03780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DR55_RS03790	COG1999	signal sequence binding
DR55_RS03820	COG3511	phospholipase C
DR55_RS03840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DR55_RS03870	COG0596	Alpha beta hydrolase
DR55_RS03880	COG0583	DNA-binding transcription factor activity
DR55_RS03885	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR55_RS03900	COG0840	transmembrane signaling receptor activity
DR55_RS03905	COG1609	Transcriptional regulator
DR55_RS03955	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DR55_RS03960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DR55_RS03980	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DR55_RS03985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DR55_RS04005	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DR55_RS04010	COG1704	LemA family
DR55_RS04100	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR55_RS04110	COG2824	Alkylphosphonate utilization operon protein PhnA
DR55_RS04130	COG0583	DNA-binding transcription factor activity
DR55_RS04135	COG2233	PERMEase
DR55_RS04140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DR55_RS04150	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DR55_RS04160	COG1706	bacterial-type flagellum-dependent cell motility
DR55_RS04165	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DR55_RS04180	COG1749	Flagellar hook protein flgE
DR55_RS04185	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DR55_RS04190	COG1558	bacterial-type flagellum-dependent cell motility
DR55_RS04195	COG1815	bacterial-type flagellum-dependent cell motility
DR55_RS04205	COG2747	anti-sigma28 factor FlgM
DR55_RS04240	COG0741	lytic transglycosylase activity
DR55_RS04245	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DR55_RS04255	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DR55_RS04260	COG1984	allophanate hydrolase subunit 2
DR55_RS04290	COG4608	Belongs to the ABC transporter superfamily
DR55_RS04295	COG0444	Belongs to the ABC transporter superfamily
DR55_RS04300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DR55_RS04305	COG0601	transmembrane transport
DR55_RS04310	COG0747	negative chemotaxis
DR55_RS04325	COG0579	oxidoreductase
DR55_RS04345	COG3568	Endonuclease Exonuclease Phosphatase
DR55_RS04350	COG1280	lysine exporter protein (LysE YggA)
DR55_RS04370	COG0531	amino acid
DR55_RS04385	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DR55_RS04445	COG1960	acyl-CoA dehydrogenase activity
DR55_RS04460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DR55_RS04470	COG2814	Major facilitator Superfamily
DR55_RS04485	COG0667	Aldo Keto reductase
DR55_RS04510	COG1560	Kdo2-lipid A biosynthetic process
DR55_RS04525	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DR55_RS04535	COG0523	cobalamin synthesis protein
DR55_RS04555	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DR55_RS04580	COG1309	transcriptional regulator
DR55_RS04595	COG2814	Major facilitator Superfamily
DR55_RS04605	COG2207	Transcriptional regulator
DR55_RS04610	COG1064	alcohol dehydrogenase
DR55_RS04620	COG0708	Exodeoxyribonuclease III
DR55_RS04625	COG2326	polyphosphate kinase activity
DR55_RS04645	COG1077	Cell shape determining protein MreB Mrl
DR55_RS04660	COG0768	penicillin binding
DR55_RS04665	COG0772	Belongs to the SEDS family
DR55_RS04680	COG0720	synthase
DR55_RS04685	COG0602	queuosine metabolic process
DR55_RS04700	COG2204	response regulator
DR55_RS04705	COG5000	phosphorelay sensor kinase activity
DR55_RS04715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DR55_RS04715	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DR55_RS04735	COG0242	peptide deformylase activity
DR55_RS04740	COG0758	DNA mediated transformation
DR55_RS04755	COG0583	DNA-binding transcription factor activity
DR55_RS04760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DR55_RS04805	COG4695	Portal protein
DR55_RS04820	COG1176	ABC-type spermidine putrescine transport system, permease component I
DR55_RS04825	COG1177	transmembrane transport
DR55_RS04835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DR55_RS04850	COG0583	DNA-binding transcription factor activity
DR55_RS04870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DR55_RS04885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DR55_RS04885	COG2169	Transcriptional regulator
DR55_RS04905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DR55_RS04960	COG0582	viral genome integration into host DNA
DR55_RS05000	COG0592	DNA-directed DNA polymerase activity
DR55_RS05010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DR55_RS05020	COG1205	dead DEAH box helicase
DR55_RS05020	COG1111	helicase
DR55_RS05085	COG0753	catalase activity
DR55_RS05125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DR55_RS05130	COG1250	3-hydroxyacyl-CoA dehydrogenase
DR55_RS05130	COG1024	Enoyl-CoA hydratase
DR55_RS05135	COG0183	Belongs to the thiolase family
DR55_RS05145	COG1960	acyl-CoA dehydrogenase activity
DR55_RS05170	COG1695	Transcriptional regulator
DR55_RS05230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR55_RS05255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR55_RS05270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DR55_RS05280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DR55_RS05290	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DR55_RS05290	COG4106	trans-aconitate 2-methyltransferase activity
DR55_RS05295	COG0789	Transcriptional regulator
DR55_RS05305	COG1987	bacterial-type flagellum assembly
DR55_RS05320	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DR55_RS05340	COG1346	cytolysis
DR55_RS05350	COG0583	DNA-binding transcription factor activity
DR55_RS05355	COG2814	Major facilitator Superfamily
DR55_RS05360	COG1846	Transcriptional regulator
DR55_RS05405	COG2165	general secretion pathway protein
DR55_RS05420	COG1459	type II secretion system
DR55_RS05440	COG0523	cobalamin synthesis protein
DR55_RS05470	COG0519	Catalyzes the synthesis of GMP from XMP
DR55_RS05470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DR55_RS05475	COG1902	pentaerythritol trinitrate reductase activity
DR55_RS05490	COG0642	Histidine kinase
DR55_RS05510	COG3186	Phenylalanine-4-hydroxylase
DR55_RS05515	COG1522	sequence-specific DNA binding
DR55_RS05525	COG0583	DNA-binding transcription factor activity
DR55_RS05535	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DR55_RS05555	COG0559	Belongs to the binding-protein-dependent transport system permease family
DR55_RS05600	COG1192	Involved in chromosome partitioning
DR55_RS05605	COG1475	DNA binding
DR55_RS05610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DR55_RS05620	COG0356	it plays a direct role in the translocation of protons across the membrane
DR55_RS05660	COG0318	PFAM AMP-dependent synthetase and ligase
DR55_RS05665	COG1832	CoA-binding protein
DR55_RS05680	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DR55_RS05690	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DR55_RS05690	COG0506	proline dehydrogenase activity
DR55_RS05690	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DR55_RS05705	COG1960	acyl-CoA dehydrogenase activity
DR55_RS05720	COG0436	Aminotransferase
DR55_RS05735	COG0277	FAD linked oxidase domain protein
DR55_RS05745	COG0789	Transcriptional regulator
DR55_RS05765	COG0668	transmembrane transport
DR55_RS05785	COG0531	amino acid
DR55_RS05790	COG4303	Ethanolamine ammonia lyase large subunit
DR55_RS05795	COG4302	ethanolamine ammonia-lyase activity
DR55_RS05805	COG1012	belongs to the aldehyde dehydrogenase family
DR55_RS05830	COG1760	l-serine dehydratase
DR55_RS05845	COG0509	glycine decarboxylation via glycine cleavage system
DR55_RS05860	COG0673	inositol 2-dehydrogenase activity
DR55_RS05875	COG0210	DNA helicase
DR55_RS05880	COG3245	cytochrome
DR55_RS05890	COG0582	viral genome integration into host DNA
DR55_RS05915	COG3397	chitin binding
DR55_RS05935	COG2267	carboxylic ester hydrolase activity
DR55_RS05990	COG1028	Short-chain dehydrogenase reductase Sdr
DR55_RS06005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DR55_RS06040	COG0519	Catalyzes the synthesis of GMP from XMP
DR55_RS06050	COG0561	phosphatase activity
DR55_RS06055	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DR55_RS06065	COG0438	transferase activity, transferring glycosyl groups
DR55_RS06085	COG1360	Flagellar Motor Protein
DR55_RS06090	COG2201	protein-glutamate methylesterase activity
DR55_RS06110	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DR55_RS06120	COG2201	protein-glutamate methylesterase activity
DR55_RS06125	COG0745	RESPONSE REGULATOR receiver
DR55_RS06130	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DR55_RS06150	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DR55_RS06155	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DR55_RS06180	COG1950	PFAM Membrane protein of
DR55_RS06185	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DR55_RS06200	COG2070	2-Nitropropane dioxygenase
DR55_RS06225	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DR55_RS06230	COG1522	sequence-specific DNA binding
DR55_RS06240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DR55_RS06260	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DR55_RS06265	COG2823	Periplasmic or secreted lipoprotein
DR55_RS06280	COG1113	amino acid transport
DR55_RS06310	COG2084	Dehydrogenase
DR55_RS06315	COG1280	lysine exporter protein (LysE YggA)
DR55_RS06320	COG2814	Major facilitator Superfamily
DR55_RS06325	COG0583	DNA-binding transcription factor activity
DR55_RS06330	COG3047	cAMP biosynthetic process
DR55_RS06345	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DR55_RS06355	COG1881	PFAM PEBP family protein
DR55_RS06360	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DR55_RS06365	COG0280	phosphate acetyltransferase
DR55_RS06365	COG0281	malic enzyme
DR55_RS06385	COG1522	sequence-specific DNA binding
DR55_RS06405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DR55_RS06410	COG2151	metal-sulfur cluster biosynthetic enzyme
DR55_RS06415	COG3396	Phenylacetate-CoA oxygenase
DR55_RS06420	COG3460	Phenylacetate-CoA oxygenase
DR55_RS06425	COG3396	Phenylacetate-CoA oxygenase
DR55_RS06485	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DR55_RS06525	COG0514	ATP-dependent DNA helicase (RecQ)
DR55_RS06655	COG0201	protein transport
DR55_RS06700	COG4232	protein-disulfide reductase activity
DR55_RS06720	COG1333	cytochrome c biogenesis protein
DR55_RS06725	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DR55_RS06730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DR55_RS06735	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DR55_RS06790	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DR55_RS06800	COG1175	transmembrane transport
DR55_RS06805	COG0395	ABC-type sugar transport system, permease component
DR55_RS06815	COG0584	glycerophosphoryl diester phosphodiesterase
DR55_RS06830	COG0070	glutamate synthase
DR55_RS06830	COG0067	glutamate synthase
DR55_RS06830	COG0069	glutamate synthase activity
DR55_RS06840	COG1115	amino acid carrier protein
DR55_RS06850	COG4178	(ABC) transporter
DR55_RS06875	COG1127	ABC transporter
DR55_RS06880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DR55_RS06885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DR55_RS06905	COG1131	(ABC) transporter
DR55_RS06910	COG0842	Transport permease protein
DR55_RS06945	COG2095	MarC family integral membrane protein
DR55_RS06995	COG0805	protein transport
DR55_RS07005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DR55_RS07010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DR55_RS07015	COG0723	plastoquinol--plastocyanin reductase activity
DR55_RS07020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DR55_RS07025	COG2857	Cytochrome c1
DR55_RS07030	COG0625	glutathione transferase activity
DR55_RS07035	COG2969	positive regulation of protein catabolic process
DR55_RS07050	COG2963	transposase activity
DR55_RS07055	COG2801	Transposase and inactivated derivatives
DR55_RS07070	COG0582	viral genome integration into host DNA
DR55_RS07190	COG0308	aminopeptidase N
DR55_RS07235	COG0443	Heat shock 70 kDa protein
DR55_RS07240	COG1278	Cold shock
DR55_RS07245	COG0531	amino acid
DR55_RS07250	COG3384	dioxygenase
DR55_RS07260	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DR55_RS07265	COG2890	protein-(glutamine-N5) methyltransferase activity
DR55_RS07295	COG0006	proline dipeptidase activity
DR55_RS07305	COG1335	isochorismatase
DR55_RS07315	COG0488	(ABC) transporter
DR55_RS07330	COG0584	glycerophosphoryl diester phosphodiesterase
DR55_RS07360	COG0012	GTP binding
DR55_RS07375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DR55_RS07380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DR55_RS07395	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DR55_RS07415	COG0512	Glutamine amidotransferase of anthranilate synthase
DR55_RS07425	COG0546	phosphoglycolate phosphatase activity
DR55_RS07430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DR55_RS07435	COG2967	ApaG domain
DR55_RS07445	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DR55_RS07455	COG2050	protein possibly involved in aromatic compounds catabolism
DR55_RS07460	COG1024	Enoyl-CoA hydratase
DR55_RS07465	COG0183	Belongs to the thiolase family
DR55_RS07475	COG1024	Enoyl-CoA hydratase
DR55_RS07505	COG0243	molybdopterin cofactor binding
DR55_RS07510	COG0318	PFAM AMP-dependent synthetase and ligase
DR55_RS07515	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR55_RS07530	COG0275	rRNA processing
DR55_RS07535	COG3116	cell division
DR55_RS07545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DR55_RS07550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DR55_RS07585	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DR55_RS07600	COG0678	peroxiredoxin activity
DR55_RS07630	COG0494	nUDIX hydrolase
DR55_RS07635	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DR55_RS07650	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DR55_RS07660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DR55_RS07665	COG4536	flavin adenine dinucleotide binding
DR55_RS07675	COG0142	geranyltranstransferase activity
DR55_RS07715	COG2095	MarC family integral membrane protein
DR55_RS07720	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DR55_RS07725	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DR55_RS07765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DR55_RS07770	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DR55_RS07785	COG0439	Biotin carboxylase
DR55_RS07790	COG0511	ligase activity, forming carbon-carbon bonds
DR55_RS07795	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DR55_RS07800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DR55_RS07810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DR55_RS07815	COG3150	esterase
DR55_RS07820	COG0557	exoribonuclease II activity
DR55_RS07825	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DR55_RS07830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DR55_RS07845	COG1414	Transcriptional regulator
DR55_RS07850	COG3734	2-keto-3-deoxy-galactonokinase
DR55_RS07860	COG1028	Short-chain dehydrogenase reductase Sdr
DR55_RS07875	COG1172	Belongs to the binding-protein-dependent transport system permease family
DR55_RS07880	COG1028	Short-chain dehydrogenase reductase Sdr
DR55_RS07890	COG0284	orotidine-5'-phosphate decarboxylase activity
DR55_RS07895	COG1546	Belongs to the CinA family
DR55_RS07900	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DR55_RS07925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DR55_RS07935	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DR55_RS07940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DR55_RS07945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DR55_RS07950	COG2814	Major facilitator Superfamily
DR55_RS07965	COG0583	DNA-binding transcription factor activity
DR55_RS07975	COG1301	dicarboxylic acid transport
DR55_RS07980	COG4266	Belongs to the allantoicase family
DR55_RS07985	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DR55_RS07990	COG0735	belongs to the Fur family
DR55_RS07995	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DR55_RS08025	COG1466	dna polymerase III delta subunit
DR55_RS08030	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DR55_RS08035	COG1981	membrane
DR55_RS08040	COG0837	glucose binding
DR55_RS08040	COG1737	Transcriptional regulator
DR55_RS08050	COG0800	Aldolase
DR55_RS08070	COG2223	nitrite transmembrane transporter activity
DR55_RS08075	COG0583	DNA-binding transcription factor activity
DR55_RS08080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DR55_RS08085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DR55_RS08090	COG0765	amino acid transport
DR55_RS08095	COG0765	amino acid transport
DR55_RS08100	COG1126	abc transporter atp-binding protein
DR55_RS08130	COG0121	glutamine amidotransferase
DR55_RS08135	COG0418	dihydroorotase activity
DR55_RS08165	COG4977	sequence-specific DNA binding
DR55_RS08165	COG1917	Cupin 2, conserved barrel domain protein
DR55_RS08170	COG0625	glutathione transferase activity
DR55_RS08175	COG0625	glutathione transferase activity
DR55_RS08185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DR55_RS08195	COG0588	phosphoglycerate mutase activity
DR55_RS08230	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DR55_RS08235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DR55_RS08240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DR55_RS08245	COG0006	proline dipeptidase activity
DR55_RS08250	COG0625	glutathione transferase activity
DR55_RS08255	COG0069	glutamate synthase activity
DR55_RS08325	COG3008	intermembrane lipid transfer
DR55_RS08325	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DR55_RS08330	COG2995	paraquat-inducible protein a
DR55_RS08345	COG2353	YceI-like domain
DR55_RS08350	COG2353	YceI-like domain
DR55_RS08360	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DR55_RS08365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DR55_RS08370	COG1862	Preprotein translocase
DR55_RS08375	COG0343	queuine tRNA-ribosyltransferase activity
DR55_RS08385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DR55_RS08405	COG0783	Belongs to the Dps family
DR55_RS08420	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DR55_RS08425	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DR55_RS08430	COG2188	Transcriptional regulator
DR55_RS08435	COG3624	Phosphonate C-P lyase system protein PhnG
DR55_RS08445	COG3626	phosphonate metabolism
DR55_RS08450	COG3627	carbon phosphorus lyase activity
DR55_RS08455	COG4107	phosphonate C-P lyase system protein PhnK
DR55_RS08460	COG4778	phosphonate C-P lyase system protein PhnL
DR55_RS08465	COG3454	Phosphonate metabolism
DR55_RS08475	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DR55_RS08480	COG3639	organic phosphonate transmembrane transporter activity
DR55_RS08495	COG0247	lactate metabolic process
DR55_RS08500	COG0277	FAD linked oxidase domain protein
DR55_RS08505	COG0277	FAD linked oxidase domain protein
DR55_RS08510	COG0277	FAD linked oxidase domain protein
DR55_RS08515	COG2096	Adenosyltransferase
DR55_RS08520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DR55_RS08520	COG1017	nitric oxide dioxygenase activity
DR55_RS08530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DR55_RS08535	COG0312	modulator of DNA gyrase
DR55_RS08540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DR55_RS08545	COG3164	Protein of unknown function
DR55_RS08550	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DR55_RS08555	COG0497	DNA recombination
DR55_RS08560	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DR55_RS08600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DR55_RS08610	COG1428	Deoxynucleoside kinase
DR55_RS08615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DR55_RS08620	COG0617	tRNA 3'-terminal CCA addition
DR55_RS08630	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DR55_RS08650	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DR55_RS08655	COG0586	Pfam SNARE associated Golgi protein
DR55_RS08755	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DR55_RS08770	COG1368	sulfuric ester hydrolase activity
DR55_RS08775	COG1028	Short-chain dehydrogenase reductase Sdr
DR55_RS08775	COG0604	alcohol dehydrogenase
DR55_RS08775	COG3321	synthase
DR55_RS08780	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DR55_RS08785	COG0156	8-amino-7-oxononanoate synthase activity
DR55_RS08825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DR55_RS08830	COG3206	protein involved in exopolysaccharide biosynthesis
DR55_RS08830	COG0489	protein tyrosine kinase activity
DR55_RS08840	COG3562	capsule polysaccharide
DR55_RS08845	COG1045	serine acetyltransferase
DR55_RS08860	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DR55_RS08865	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DR55_RS08870	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DR55_RS08870	COG0517	IMP dehydrogenase activity
DR55_RS08895	COG2885	chlorophyll binding
DR55_RS08920	COG0824	Thioesterase
DR55_RS08925	COG4221	oxidoreductase activity
DR55_RS08980	COG0450	alkyl hydroperoxide reductase
DR55_RS08990	COG1960	acyl-CoA dehydrogenase activity
DR55_RS09015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DR55_RS09025	COG2814	Major facilitator Superfamily
DR55_RS09045	COG2814	Major facilitator Superfamily
DR55_RS09050	COG0778	Nitroreductase
DR55_RS09055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DR55_RS09060	COG0583	DNA-binding transcription factor activity
DR55_RS09065	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DR55_RS09090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DR55_RS09105	COG4774	siderophore transport
DR55_RS09110	COG1120	ATPase activity
DR55_RS09120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DR55_RS09160	COG0730	response to heat
DR55_RS09170	COG0584	glycerophosphoryl diester phosphodiesterase
DR55_RS09175	COG1280	lysine exporter protein (LysE YggA)
DR55_RS09225	COG0604	alcohol dehydrogenase
DR55_RS09230	COG1733	regulation of RNA biosynthetic process
DR55_RS09240	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DR55_RS09255	COG1773	rubredoxin
DR55_RS09275	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DR55_RS09350	COG1215	transferase activity, transferring glycosyl groups
DR55_RS09365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DR55_RS09380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DR55_RS09405	COG0859	PFAM glycosyl transferase family 9
DR55_RS09460	COG1129	ABC transporter
DR55_RS09470	COG0559	Belongs to the binding-protein-dependent transport system permease family
DR55_RS09480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DR55_RS09490	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DR55_RS09500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DR55_RS09520	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DR55_RS09530	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DR55_RS09535	COG2226	methyltransferase
DR55_RS09555	COG0762	integral membrane protein
DR55_RS09590	COG0436	Aminotransferase
DR55_RS09615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DR55_RS09615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DR55_RS09635	COG2814	Major facilitator Superfamily
DR55_RS09650	COG1126	abc transporter atp-binding protein
DR55_RS09655	COG0765	amino acid transport
DR55_RS09660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DR55_RS09670	COG0363	glucosamine-6-phosphate deaminase activity
DR55_RS09675	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DR55_RS09685	COG1175	transmembrane transport
DR55_RS09690	COG0395	ABC-type sugar transport system, permease component
DR55_RS09695	COG3842	ATPase activity
DR55_RS09700	COG2860	membrane
DR55_RS09705	COG1193	negative regulation of DNA recombination
DR55_RS09710	COG0492	ferredoxin-NADP+ reductase activity
DR55_RS09715	COG1674	ftsk spoiiie
DR55_RS09720	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DR55_RS09725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DR55_RS09760	COG2894	cell division
DR55_RS09785	COG0859	PFAM glycosyl transferase family 9
DR55_RS09795	COG0477	Major facilitator Superfamily
DR55_RS09825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DR55_RS09830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DR55_RS09840	COG1561	YicC-like family, N-terminal region
DR55_RS09855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DR55_RS09875	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR55_RS09885	COG1278	Cold shock
DR55_RS09890	COG2176	DNA-directed DNA polymerase activity
DR55_RS09910	COG4772	TonB-dependent receptor
DR55_RS09960	COG0583	DNA-binding transcription factor activity
DR55_RS09970	COG0308	aminopeptidase N
DR55_RS09980	COG2119	membrane
DR55_RS09985	COG0402	S-adenosylhomocysteine deaminase activity
DR55_RS09990	COG2252	PERMEase
DR55_RS09995	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DR55_RS10015	COG0154	amidase activity
DR55_RS10020	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DR55_RS10045	COG3383	formate dehydrogenase (NAD+) activity
DR55_RS10060	COG1910	domain protein
DR55_RS10070	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DR55_RS10075	COG0546	phosphoglycolate phosphatase activity
DR55_RS10100	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DR55_RS10105	COG0077	Prephenate dehydratase
DR55_RS10105	COG1605	Chorismate mutase
DR55_RS10110	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DR55_RS10135	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DR55_RS10145	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DR55_RS10170	COG2951	lytic endotransglycosylase activity
DR55_RS10175	COG0123	including yeast histone deacetylase and acetoin utilization protein
DR55_RS10180	COG2267	carboxylic ester hydrolase activity
DR55_RS10190	COG2011	ABC-type metal ion transport system permease component
DR55_RS10210	COG1960	acyl-CoA dehydrogenase activity
DR55_RS10270	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DR55_RS10290	COG0501	Belongs to the peptidase M48B family
DR55_RS10300	COG0521	Mo-molybdopterin cofactor biosynthetic process
DR55_RS10305	COG3028	Belongs to the UPF0307 family
DR55_RS10310	COG0312	modulator of DNA gyrase
DR55_RS10320	COG2204	response regulator
DR55_RS10355	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DR55_RS10365	COG0640	Transcriptional regulator
DR55_RS10385	COG0114	fumarate hydratase activity
DR55_RS10395	COG0534	Mate efflux family protein
DR55_RS10400	COG2501	S4 domain
DR55_RS10420	COG3045	CreA protein
DR55_RS10435	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DR55_RS10440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DR55_RS10460	COG1322	Protein conserved in bacteria
DR55_RS10475	COG0303	'Molybdopterin
DR55_RS10485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DR55_RS10490	COG1530	ribonuclease E activity
DR55_RS10500	COG0546	phosphoglycolate phosphatase activity
DR55_RS10525	COG1399	metal-binding, possibly nucleic acid-binding protein
DR55_RS10560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DR55_RS10580	COG3026	antisigma factor binding
DR55_RS10585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DR55_RS10600	COG0681	Belongs to the peptidase S26 family
DR55_RS10605	COG0571	ribonuclease III activity
DR55_RS10610	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DR55_RS10635	COG2204	response regulator
DR55_RS10650	COG0322	excinuclease ABC activity
DR55_RS10655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DR55_RS10675	COG1956	GAF domain-containing protein
DR55_RS10680	COG0583	DNA-binding transcription factor activity
DR55_RS10690	COG2153	protein acetylation
DR55_RS10705	COG1999	signal sequence binding
DR55_RS10715	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DR55_RS10720	COG1132	(ABC) transporter
DR55_RS10725	COG0438	transferase activity, transferring glycosyl groups
DR55_RS10740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DR55_RS10745	COG0683	leucine binding
DR55_RS10755	COG3511	phospholipase C
DR55_RS10765	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DR55_RS10770	COG0596	Alpha beta hydrolase
DR55_RS10775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DR55_RS10790	COG3394	polysaccharide catabolic process
DR55_RS10825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DR55_RS10860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DR55_RS10870	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DR55_RS10895	COG1959	2 iron, 2 sulfur cluster binding
DR55_RS10905	COG2151	metal-sulfur cluster biosynthetic enzyme
DR55_RS10910	COG0822	iron-sulfur transferase activity
DR55_RS10915	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DR55_RS10925	COG0396	ATPase activity
DR55_RS10930	COG0719	Fe-S assembly protein
DR55_RS10940	COG0840	transmembrane signaling receptor activity
DR55_RS10945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DR55_RS10950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DR55_RS10965	COG0826	peptidase U32
DR55_RS10970	COG0826	peptidase U32
DR55_RS10975	COG3154	lipid carrier protein
DR55_RS11010	COG2151	metal-sulfur cluster biosynthetic enzyme
DR55_RS11025	COG0415	Belongs to the DNA photolyase family
DR55_RS11030	COG0529	Catalyzes the synthesis of activated sulfate
DR55_RS11065	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DR55_RS11080	COG0402	S-adenosylhomocysteine deaminase activity
DR55_RS11105	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DR55_RS11110	COG0174	glutamine synthetase
DR55_RS11140	COG0583	DNA-binding transcription factor activity
DR55_RS11145	COG1960	acyl-CoA dehydrogenase activity
DR55_RS11155	COG0477	Major facilitator Superfamily
DR55_RS11165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DR55_RS11165	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DR55_RS11170	COG1643	Atp-dependent helicase
DR55_RS11190	COG1058	Belongs to the CinA family
DR55_RS11190	COG1546	Belongs to the CinA family
DR55_RS11200	COG0174	glutamine synthetase
DR55_RS11220	COG2197	response regulator
DR55_RS11225	COG4585	Histidine kinase
DR55_RS11230	COG2181	nitrate reductase activity
DR55_RS11235	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DR55_RS11240	COG1140	nitrate reductase beta subunit
DR55_RS11245	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DR55_RS11250	COG2223	nitrite transmembrane transporter activity
DR55_RS11265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DR55_RS11270	COG0339	signal peptide processing
DR55_RS11280	COG4566	intracellular signal transduction
DR55_RS11290	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DR55_RS11295	COG0508	dehydrogenase complex catalyzes the overall conversion of
DR55_RS11300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DR55_RS11320	COG1414	Transcriptional regulator
DR55_RS11340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DR55_RS11350	COG1104	cysteine desulfurase activity
DR55_RS11355	COG0822	iron-sulfur transferase activity
DR55_RS11360	COG0316	Belongs to the HesB IscA family
DR55_RS11380	COG2975	iron-sulfur cluster assembly
DR55_RS11405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DR55_RS11420	COG1136	(ABC) transporter
DR55_RS11425	COG0084	hydrolase, TatD family'
DR55_RS11430	COG2333	competence protein COMEC
DR55_RS11430	COG0658	competence protein
DR55_RS11435	COG2267	carboxylic ester hydrolase activity
DR55_RS11455	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DR55_RS11465	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DR55_RS11475	COG2833	Protein of unknown function (DUF455)
DR55_RS11480	COG0596	Alpha beta hydrolase
DR55_RS11485	COG0613	PHP domain protein
DR55_RS11490	COG0009	L-threonylcarbamoyladenylate synthase
DR55_RS11495	COG1994	Peptidase M50
DR55_RS11500	COG0180	Tryptophanyl-tRNA synthetase
DR55_RS11510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DR55_RS11515	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DR55_RS11520	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DR55_RS11525	COG2850	peptidyl-arginine hydroxylation
DR55_RS11830	COG0483	inositol monophosphate 1-phosphatase activity
DR55_RS11840	COG1045	serine acetyltransferase
DR55_RS11845	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DR55_RS11855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DR55_RS11880	COG0037	tRNA processing
DR55_RS11885	COG0527	aspartate kinase activity
DR55_RS11925	COG0529	Catalyzes the synthesis of activated sulfate
DR55_RS11925	COG2895	sulfate adenylyltransferase (ATP) activity
DR55_RS11930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DR55_RS11955	COG2175	clavaminate synthase activity
DR55_RS11975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DR55_RS11980	COG3958	Transketolase
DR55_RS11995	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DR55_RS12015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DR55_RS12030	COG0024	Methionine aminopeptidase
DR55_RS12060	COG0243	molybdopterin cofactor binding
DR55_RS12080	COG4166	transmembrane transport
DR55_RS12085	COG4174	ABC transporter (Permease)
DR55_RS12090	COG4239	(ABC) transporter, permease
DR55_RS12095	COG4172	Belongs to the ABC transporter superfamily
DR55_RS12100	COG0791	NLP P60 protein
DR55_RS12105	COG1752	Esterase of the alpha-beta hydrolase superfamily
DR55_RS12165	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DR55_RS12175	COG0583	DNA-binding transcription factor activity
DR55_RS12185	COG2224	Isocitrate lyase
DR55_RS12190	COG0513	Belongs to the DEAD box helicase family
DR55_RS12200	COG1214	PFAM Peptidase M22, glycoprotease
DR55_RS12210	COG1573	uracil-dna glycosylase
DR55_RS12225	COG0351	phosphomethylpyrimidine kinase
DR55_RS12230	COG0477	Major facilitator Superfamily
DR55_RS12250	COG0488	(ABC) transporter
DR55_RS12255	COG0386	Belongs to the glutathione peroxidase family
DR55_RS12270	COG2890	protein-(glutamine-N5) methyltransferase activity
DR55_RS12280	COG1393	Belongs to the ArsC family
DR55_RS12320	COG0242	peptide deformylase activity
DR55_RS12325	COG1187	pseudouridine synthase activity
DR55_RS12335	COG0024	Methionine aminopeptidase
DR55_RS12365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DR55_RS12380	COG0750	zinc metalloprotease
DR55_RS12410	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DR55_RS12420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DR55_RS12455	COG0330	HflC and HflK could
DR55_RS12465	COG2867	negative regulation of translational initiation
DR55_RS12475	COG0697	spore germination
DR55_RS12510	COG2814	Major facilitator Superfamily
DR55_RS12530	COG1619	proteins homologs of microcin C7 resistance protein MccF
DR55_RS12540	COG1953	Uracil, thiamine, allantoin
DR55_RS12555	COG3195	allantoin biosynthetic process
DR55_RS12555	COG3648	Uricase
DR55_RS12560	COG4266	Belongs to the allantoicase family
DR55_RS12575	COG2351	hydroxyisourate hydrolase activity
DR55_RS12585	COG0583	DNA-binding transcription factor activity
DR55_RS12595	COG3360	Dodecin
DR55_RS12650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DR55_RS12665	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DR55_RS12775	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DR55_RS12780	COG1846	Transcriptional regulator
DR55_RS12785	COG1929	Belongs to the glycerate kinase type-1 family
DR55_RS12805	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DR55_RS12835	COG3547	Transposase (IS116 IS110 IS902 family)
DR55_RS12860	COG4181	ATPase activity
DR55_RS12875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DR55_RS12885	COG0047	phosphoribosylformylglycinamidine synthase activity
DR55_RS12885	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DR55_RS12895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DR55_RS12920	COG0318	PFAM AMP-dependent synthetase and ligase
DR55_RS12925	COG1024	Enoyl-CoA hydratase
DR55_RS12925	COG1250	3-hydroxyacyl-CoA dehydrogenase
DR55_RS12930	COG1335	isochorismatase
DR55_RS12935	COG0183	Belongs to the thiolase family
DR55_RS12955	COG2130	NADP-dependent
DR55_RS12960	COG0657	acetylesterase activity
DR55_RS12975	COG0354	folic acid binding
DR55_RS12980	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DR55_RS12995	COG1247	-acetyltransferase
DR55_RS13000	COG0084	hydrolase, TatD family'
DR55_RS13025	COG0438	transferase activity, transferring glycosyl groups
DR55_RS13045	COG0252	asparaginase activity
DR55_RS13050	COG1652	LysM domain
DR55_RS13060	COG2084	Dehydrogenase
DR55_RS13065	COG3622	Belongs to the hyi family
DR55_RS13070	COG3960	tartronate-semialdehyde synthase activity
DR55_RS13075	COG0583	DNA-binding transcription factor activity
DR55_RS13130	COG0306	phosphate transporter
DR55_RS13135	COG0791	NLP P60 protein
DR55_RS13140	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DR55_RS13145	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DR55_RS13150	COG0726	polysaccharide deacetylase
DR55_RS13155	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DR55_RS13155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DR55_RS13165	COG0463	Glycosyl transferase, family 2
DR55_RS13170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DR55_RS13175	COG2076	Multidrug Resistance protein
DR55_RS13180	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DR55_RS13190	COG0436	Aminotransferase
DR55_RS13210	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DR55_RS13215	COG0314	molybdopterin synthase activity
DR55_RS13220	COG2346	COG2346, Truncated hemoglobins
DR55_RS13225	COG1959	2 iron, 2 sulfur cluster binding
DR55_RS13230	COG0542	response to heat
DR55_RS13255	COG0534	Mate efflux family protein
DR55_RS13270	COG3228	Belongs to the MtfA family
DR55_RS13275	COG0477	Major facilitator Superfamily
DR55_RS13280	COG0789	Transcriptional regulator
DR55_RS13285	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DR55_RS13300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DR55_RS13315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DR55_RS13360	COG0670	Belongs to the BI1 family
DR55_RS13395	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DR55_RS13410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DR55_RS13415	COG0330	HflC and HflK could
DR55_RS13420	COG0330	HflC and HflK could
DR55_RS13440	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DR55_RS13450	COG2183	response to ionizing radiation
DR55_RS13465	COG1199	ATP-dependent helicase activity
DR55_RS13475	COG0564	pseudouridine synthase activity
DR55_RS13480	COG1496	oxidoreductase activity
DR55_RS13485	COG3243	poly(R)-hydroxyalkanoic acid synthase
DR55_RS13490	COG0183	Belongs to the thiolase family
DR55_RS13495	COG1028	Short-chain dehydrogenase reductase Sdr
DR55_RS13515	COG0183	Belongs to the thiolase family
DR55_RS13525	COG0626	cystathionine gamma-synthase activity
DR55_RS13530	COG0560	Phosphoserine phosphatase
DR55_RS13540	COG0390	transport system, permease component
DR55_RS13545	COG1122	ATPase activity
DR55_RS13550	COG2982	Protein involved in outer membrane biogenesis
DR55_RS13555	COG0488	(ABC) transporter
DR55_RS13570	COG2070	2-Nitropropane dioxygenase
DR55_RS13575	COG3047	cAMP biosynthetic process
DR55_RS13585	COG1914	H( )-stimulated, divalent metal cation uptake system
DR55_RS13590	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DR55_RS13595	COG3842	ATPase activity
DR55_RS13600	COG1176	ABC-type spermidine putrescine transport system, permease component I
DR55_RS13605	COG1177	transmembrane transport
DR55_RS13610	COG0730	response to heat
DR55_RS13610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DR55_RS13635	COG3655	Transcriptional regulator
DR55_RS13655	COG1538	Outer membrane efflux protein
DR55_RS13660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DR55_RS13675	COG0038	chloride channel
DR55_RS13680	COG2855	membrane
DR55_RS13700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DR55_RS13710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DR55_RS13715	COG1609	Transcriptional regulator
DR55_RS13800	COG0598	Magnesium transport protein CorA
DR55_RS13805	COG2350	Protein conserved in bacteria
DR55_RS13830	COG1196	nuclear chromosome segregation
DR55_RS13830	COG3264	Mechanosensitive ion channel
DR55_RS13860	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DR55_RS13875	COG4263	nitrous-oxide reductase activity
DR55_RS13895	COG0840	transmembrane signaling receptor activity
DR55_RS13905	COG2376	Dihydroxyacetone kinase
DR55_RS13925	COG0475	glutathione-regulated potassium exporter activity
DR55_RS13985	COG3121	Chaperone
DR55_RS13990	COG3188	usher protein
DR55_RS14020	COG5295	Hep Hag repeat protein
DR55_RS14035	COG2197	response regulator
DR55_RS14065	COG3328	transposase activity
DR55_RS14100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DR55_RS14105	COG1012	belongs to the aldehyde dehydrogenase family
DR55_RS14120	COG1176	ABC-type spermidine putrescine transport system, permease component I
DR55_RS14130	COG3842	ATPase activity
DR55_RS14145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR55_RS14155	COG2916	Histone family protein nucleoid-structuring protein H-NS
DR55_RS14185	COG2274	protein secretion by the type I secretion system
DR55_RS14190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DR55_RS14200	COG0457	Tetratricopeptide repeat
DR55_RS14200	COG0859	PFAM glycosyl transferase family 9
DR55_RS14210	COG0529	Catalyzes the synthesis of activated sulfate
DR55_RS14215	COG0745	RESPONSE REGULATOR receiver
DR55_RS14240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR55_RS14250	COG2986	histidine ammonia-lyase
DR55_RS14260	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DR55_RS14275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DR55_RS14290	COG1595	DNA-templated transcription, initiation
DR55_RS14295	COG4944	Protein of unknown function (DUF1109)
DR55_RS14315	COG3220	belongs to the UPF0276 family
DR55_RS14335	COG2192	nodulation
DR55_RS14360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DR55_RS14380	COG0165	Argininosuccinate lyase
DR55_RS14385	COG0137	argininosuccinate synthase activity
DR55_RS14400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DR55_RS14410	COG3251	PFAM MbtH domain protein
DR55_RS14425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR55_RS14430	COG2207	Transcriptional regulator
DR55_RS14435	COG0697	spore germination
DR55_RS14440	COG0835	chemotaxis
DR55_RS14460	COG0318	PFAM AMP-dependent synthetase and ligase
DR55_RS14465	COG0477	Major facilitator Superfamily
DR55_RS14475	COG1732	Glycine betaine
DR55_RS14480	COG1174	glycine betaine transport
DR55_RS14485	COG1125	glycine betaine transport
DR55_RS14490	COG1174	glycine betaine transport
DR55_RS14505	COG2235	arginine
DR55_RS14510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DR55_RS14535	COG0583	DNA-binding transcription factor activity
DR55_RS14540	COG0625	glutathione transferase activity
DR55_RS14555	COG1846	Transcriptional regulator
DR55_RS14560	COG2807	transmembrane transport
DR55_RS14565	COG1649	PFAM Uncharacterised BCR, COG1649
DR55_RS14580	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DR55_RS14590	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DR55_RS14610	COG3979	chitinase
DR55_RS14620	COG0400	carboxylic ester hydrolase activity
DR55_RS14625	COG4644	lycopene metabolic process
DR55_RS14640	COG4974	Belongs to the 'phage' integrase family
DR55_RS14670	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DR55_RS14695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DR55_RS14700	COG4774	siderophore transport
DR55_RS14705	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DR55_RS14750	COG1120	ATPase activity
DR55_RS14780	COG1028	Short-chain dehydrogenase reductase Sdr
DR55_RS14785	COG1070	Carbohydrate kinase
DR55_RS14790	COG1063	alcohol dehydrogenase
DR55_RS14795	COG1172	Belongs to the binding-protein-dependent transport system permease family
DR55_RS14805	COG1879	ABC-type sugar transport system periplasmic component
DR55_RS14825	COG1132	(ABC) transporter
DR55_RS14825	COG2375	cellular response to nickel ion
DR55_RS14835	COG3121	Chaperone
DR55_RS14845	COG3539	Fimbrial protein
DR55_RS14855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DR55_RS14865	COG1309	transcriptional regulator
DR55_RS14870	COG0739	heme binding
DR55_RS14875	COG0765	amino acid transport
DR55_RS14880	COG4597	amino acid ABC transporter
DR55_RS14895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DR55_RS14940	COG4964	Belongs to the GSP D family
DR55_RS14960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DR55_RS14965	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DR55_RS14980	COG0477	Major facilitator Superfamily
DR55_RS14985	COG2719	SpoVR family
DR55_RS14990	COG2718	Belongs to the UPF0229 family
DR55_RS14995	COG2766	serine protein kinase
DR55_RS15000	COG0840	transmembrane signaling receptor activity
DR55_RS15005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DR55_RS15010	COG1609	Transcriptional regulator
DR55_RS15015	COG1172	Belongs to the binding-protein-dependent transport system permease family
DR55_RS15020	COG1129	ABC transporter
DR55_RS15025	COG1879	ABC-type sugar transport system periplasmic component
DR55_RS15030	COG0583	DNA-binding transcription factor activity
DR55_RS15035	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DR55_RS15040	COG4208	sulfate ABC transporter
DR55_RS15045	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DR55_RS15050	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DR55_RS15075	COG1131	(ABC) transporter
DR55_RS15090	COG0701	Predicted permease
DR55_RS15095	COG0667	Aldo Keto reductase
DR55_RS15120	COG1301	dicarboxylic acid transport
DR55_RS15155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DR55_RS15200	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DR55_RS15210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DR55_RS15215	COG0765	amino acid transport
DR55_RS15220	COG0673	inositol 2-dehydrogenase activity
DR55_RS15225	COG1802	Transcriptional regulator
DR55_RS15235	COG3023	N-Acetylmuramoyl-L-alanine amidase
DR55_RS15245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DR55_RS15250	COG0557	exoribonuclease II activity
DR55_RS15265	COG0840	transmembrane signaling receptor activity
DR55_RS15290	COG0519	Catalyzes the synthesis of GMP from XMP
DR55_RS15295	COG2814	Major facilitator Superfamily
DR55_RS15305	COG0318	PFAM AMP-dependent synthetase and ligase
DR55_RS15375	COG4964	Belongs to the GSP D family
DR55_RS15430	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DR55_RS15435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DR55_RS15440	COG0508	dehydrogenase complex catalyzes the overall conversion of
DR55_RS15445	COG0567	Dehydrogenase, E1 component
DR55_RS15455	COG1217	gtp-binding protein TYPA
DR55_RS15460	COG1846	Transcriptional regulator
DR55_RS15470	COG1566	PFAM secretion protein HlyD family protein
DR55_RS15475	COG2814	Major facilitator Superfamily
DR55_RS15485	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DR55_RS15500	COG0195	Participates in both transcription termination and antitermination
DR55_RS15500	COG2251	uridine kinase activity
DR55_RS15510	COG1187	pseudouridine synthase activity
DR55_RS15515	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DR55_RS15520	COG0583	DNA-binding transcription factor activity
DR55_RS15565	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DR55_RS15585	COG2755	lipolytic protein G-D-S-L family
DR55_RS15585	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DR55_RS15600	COG0776	regulation of translation
DR55_RS15625	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DR55_RS15640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DR55_RS15645	COG0251	oxidation-reduction process
DR55_RS15650	COG2267	carboxylic ester hydrolase activity
DR55_RS15660	COG0583	DNA-binding transcription factor activity
DR55_RS15675	COG1028	Short-chain dehydrogenase reductase Sdr
DR55_RS15710	COG1028	Short-chain dehydrogenase reductase Sdr
DR55_RS15735	COG0477	Major facilitator Superfamily
DR55_RS15750	COG1295	ribonuclease BN
DR55_RS15765	COG0277	FAD linked oxidase domain protein
DR55_RS15780	COG0583	DNA-binding transcription factor activity
DR55_RS15805	COG0840	transmembrane signaling receptor activity
DR55_RS15810	COG2223	nitrite transmembrane transporter activity
DR55_RS15815	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DR55_RS15820	COG0210	DNA helicase
DR55_RS15825	COG0525	valine-tRNA ligase activity
DR55_RS15830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DR55_RS15840	COG5002	protein histidine kinase activity
DR55_RS15850	COG0745	RESPONSE REGULATOR receiver
DR55_RS15860	COG0425	Belongs to the sulfur carrier protein TusA family
DR55_RS15865	COG0673	inositol 2-dehydrogenase activity
DR55_RS15870	COG0673	inositol 2-dehydrogenase activity
DR55_RS15885	COG1172	Belongs to the binding-protein-dependent transport system permease family
DR55_RS15900	COG3962	Belongs to the TPP enzyme family
DR55_RS15910	COG3718	enzyme involved in inositol metabolism
DR55_RS15920	COG0411	ABC transporter
DR55_RS15930	COG0824	Thioesterase
DR55_RS15945	COG2816	NAD+ diphosphatase activity
DR55_RS15955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DR55_RS15960	COG0477	Major facilitator Superfamily
DR55_RS15975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DR55_RS15985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DR55_RS15990	COG0494	nUDIX hydrolase
DR55_RS16010	COG1858	cytochrome C peroxidase
DR55_RS16015	COG3511	phospholipase C
DR55_RS16025	COG1566	PFAM secretion protein HlyD family protein
DR55_RS16030	COG2814	Major facilitator Superfamily
DR55_RS16035	COG1538	Outer membrane efflux protein
DR55_RS16040	COG2197	response regulator
DR55_RS16080	COG0583	DNA-binding transcription factor activity
DR55_RS16085	COG2814	Major facilitator Superfamily
DR55_RS16110	COG1914	H( )-stimulated, divalent metal cation uptake system
DR55_RS16275	COG0859	PFAM glycosyl transferase family 9
DR55_RS16275	COG0457	Tetratricopeptide repeat
DR55_RS16320	COG0745	RESPONSE REGULATOR receiver
DR55_RS16325	COG0583	DNA-binding transcription factor activity
DR55_RS16365	COG0366	Alpha amylase catalytic
DR55_RS16370	COG0366	Alpha amylase catalytic
DR55_RS16375	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DR55_RS16390	COG1640	4-alpha-glucanotransferase
DR55_RS16420	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DR55_RS16475	COG4942	peptidase
DR55_RS16480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DR55_RS16490	COG0534	Mate efflux family protein
DR55_RS16550	COG0248	Ppx GppA phosphatase
DR55_RS16555	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DR55_RS16565	COG0745	RESPONSE REGULATOR receiver
DR55_RS16580	COG0581	inorganic phosphate transmembrane transporter activity
DR55_RS16585	COG0573	inorganic phosphate transmembrane transporter activity
DR55_RS16590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DR55_RS16600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DR55_RS16605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DR55_RS16615	COG1534	Rna-binding protein
DR55_RS16625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DR55_RS16630	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DR55_RS16640	COG0505	Belongs to the CarA family
DR55_RS16665	COG0741	lytic transglycosylase activity
DR55_RS16665	COG1388	LysM domain
DR55_RS16670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DR55_RS16675	COG2226	methyltransferase
DR55_RS16680	COG0328	RNA-DNA hybrid ribonuclease activity
DR55_RS16685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DR55_RS16695	COG0477	Major facilitator Superfamily
DR55_RS16715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DR55_RS16725	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DR55_RS16745	COG3052	prosthetic group binding
DR55_RS16770	COG0583	DNA-binding transcription factor activity
DR55_RS16775	COG1250	3-hydroxyacyl-CoA dehydrogenase
DR55_RS16780	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DR55_RS16815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DR55_RS16845	COG0583	DNA-binding transcription factor activity
DR55_RS16865	COG1522	sequence-specific DNA binding
DR55_RS16870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DR55_RS16910	COG1609	Transcriptional regulator
DR55_RS16915	COG1840	ABC-type Fe3 transport system, periplasmic component
DR55_RS16920	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DR55_RS16935	COG1177	transmembrane transport
DR55_RS16940	COG3842	ATPase activity
DR55_RS16945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DR55_RS16965	COG2814	Major facilitator Superfamily
DR55_RS16970	COG0697	spore germination
DR55_RS16980	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DR55_RS16985	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
DR55_RS17025	COG2200	EAL domain
DR55_RS17035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DR55_RS17040	COG1074	ATP-dependent DNA helicase activity
DR55_RS17045	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DR55_RS17055	COG1289	transmembrane transporter activity
DR55_RS17070	COG1840	ABC-type Fe3 transport system, periplasmic component
DR55_RS17075	COG1176	ABC-type spermidine putrescine transport system, permease component I
DR55_RS17080	COG3842	ATPase activity
DR55_RS17085	COG1522	sequence-specific DNA binding
DR55_RS17100	COG1959	2 iron, 2 sulfur cluster binding
DR55_RS17130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DR55_RS17135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DR55_RS17170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DR55_RS17185	COG2010	Cytochrome c
DR55_RS17185	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DR55_RS17190	COG2863	cytochrome
DR55_RS17210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DR55_RS17220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DR55_RS17240	COG0006	proline dipeptidase activity
DR55_RS17290	COG2866	Carboxypeptidase
DR55_RS17305	COG0436	Aminotransferase
DR55_RS17315	COG1024	Enoyl-CoA hydratase
DR55_RS17320	COG0588	phosphoglycerate mutase activity
DR55_RS17330	COG1960	acyl-CoA dehydrogenase activity
DR55_RS17345	COG2030	dehydratase
DR55_RS17345	COG1012	belongs to the aldehyde dehydrogenase family
DR55_RS17350	COG1960	acyl-CoA dehydrogenase activity
DR55_RS17355	COG1960	acyl-CoA dehydrogenase activity
DR55_RS17375	COG1007	ATP synthesis coupled electron transport
DR55_RS17410	COG1034	ATP synthesis coupled electron transport
DR55_RS17420	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DR55_RS17455	COG0149	triose-phosphate isomerase activity
DR55_RS17460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DR55_RS17460	COG0604	alcohol dehydrogenase
DR55_RS17460	COG3321	synthase
DR55_RS17460	COG4221	oxidoreductase activity
DR55_RS17475	COG0683	leucine binding
DR55_RS17490	COG0288	reversible hydration of carbon dioxide
DR55_RS17495	COG0659	secondary active sulfate transmembrane transporter activity
DR55_RS17505	COG1183	phosphatidylcholine synthase activity
DR55_RS17525	COG0028	Belongs to the TPP enzyme family
DR55_RS17555	COG0438	transferase activity, transferring glycosyl groups
DR55_RS17575	COG1028	Short-chain dehydrogenase reductase Sdr
DR55_RS17580	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DR55_RS17590	COG0154	amidase activity
DR55_RS17600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DR55_RS17630	COG0745	RESPONSE REGULATOR receiver
DR55_RS17635	COG2205	protein histidine kinase activity
DR55_RS17650	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DR55_RS17655	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DR55_RS17675	COG1028	Short-chain dehydrogenase reductase Sdr
DR55_RS17690	COG0151	Belongs to the GarS family
DR55_RS17705	COG0799	negative regulation of ribosome biogenesis
DR55_RS17725	COG2233	PERMEase
DR55_RS17880	COG0513	Belongs to the DEAD box helicase family
DR55_RS17930	COG3387	PFAM Glycoside hydrolase 15-related
DR55_RS18350	COG2827	Endonuclease containing a URI domain
DR55_RS18375	COG2271	Major facilitator Superfamily
DR55_RS19155	COG1070	Carbohydrate kinase
DR55_RS19620	COG1301	dicarboxylic acid transport
DR55_RS19745	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DR55_RS19945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DR55_RS20540	COG0742	ribosomal rna small subunit methyltransferase
DR55_RS20830	COG0793	Belongs to the peptidase S41A family
DR55_RS20910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DR55_RS21005	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DR55_RS21070	COG0646	methionine synthase
DR55_RS21070	COG1410	methionine synthase
DR55_RS21215	COG3511	phospholipase C
DR55_RS21235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DR55_RS21495	COG0444	Belongs to the ABC transporter superfamily
DR55_RS21640	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DR55_RS21870	COG5000	phosphorelay sensor kinase activity
DR55_RS22680	COG1475	DNA binding
DR55_RS22740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DR55_RS22750	COG0506	proline dehydrogenase activity
DR55_RS22750	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DR55_RS22750	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DR55_RS22775	COG1960	acyl-CoA dehydrogenase activity
DR55_RS23215	COG0840	transmembrane signaling receptor activity
DR55_RS23445	COG0280	phosphate acetyltransferase
DR55_RS23445	COG0281	malic enzyme
DR55_RS23610	COG0514	ATP-dependent DNA helicase (RecQ)
DR55_RS23705	COG4232	protein-disulfide reductase activity
DR55_RS23850	COG0070	glutamate synthase
DR55_RS23850	COG0069	glutamate synthase activity
DR55_RS23850	COG0067	glutamate synthase
DR55_RS23855	COG0070	glutamate synthase
DR55_RS23855	COG0067	glutamate synthase
DR55_RS23855	COG0069	glutamate synthase activity
DR55_RS23940	COG1131	(ABC) transporter
DR55_RS24350	COG0012	GTP binding
DR55_RS24515	COG0768	penicillin binding
DR55_RS24760	COG0557	exoribonuclease II activity
DR55_RS24785	COG3734	2-keto-3-deoxy-galactonokinase
DR55_RS25175	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DR55_RS25310	COG0277	FAD linked oxidase domain protein
DR55_RS25350	COG0312	modulator of DNA gyrase
DR55_RS25500	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DR55_RS25720	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DR55_RS26135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DR55_RS26615	COG4772	TonB-dependent receptor
DR55_RS26700	COG0154	amidase activity
DR55_RS26755	COG3383	formate dehydrogenase (NAD+) activity
DR55_RS26955	COG0312	modulator of DNA gyrase
DR55_RS27090	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DR55_RS27260	COG0683	leucine binding
DR55_RS27300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DR55_RS27340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DR55_RS28475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DR55_RS28530	COG3383	formate dehydrogenase (NAD+) activity
DR55_RS28630	COG0513	Belongs to the DEAD box helicase family
DR55_RS28690	COG0488	(ABC) transporter
DR55_RS28720	COG1393	Belongs to the ArsC family
DR55_RS29530	COG0542	response to heat
DR55_RS29790	COG0183	Belongs to the thiolase family
DR55_RS29895	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DR55_RS29950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DR55_RS30020	COG1609	Transcriptional regulator
DR55_RS30170	COG4555	ABC transporter
DR55_RS30180	COG0840	transmembrane signaling receptor activity
DR55_RS30185	COG0840	transmembrane signaling receptor activity
DR55_RS30295	COG5295	Hep Hag repeat protein
DR55_RS30420	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DR55_RS30575	COG2986	histidine ammonia-lyase