locus-tag	class	description
DP51_RS00220	COG3243	poly(R)-hydroxyalkanoic acid synthase
DP51_RS00230	COG0183	Belongs to the thiolase family
DP51_RS00250	COG0183	Belongs to the thiolase family
DP51_RS00390	COG1538	Outer membrane efflux protein
DP51_RS00420	COG0038	chloride channel
DP51_RS00425	COG2855	membrane
DP51_RS01095	COG0165	Argininosuccinate lyase
DP51_RS01225	COG0318	PFAM AMP-dependent synthetase and ligase
DP51_RS01340	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DP51_RS01505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DP51_RS01630	COG3121	Chaperone
DP51_RS01735	COG2766	serine protein kinase
DP51_RS01755	COG0840	transmembrane signaling receptor activity
DP51_RS01790	COG0583	DNA-binding transcription factor activity
DP51_RS02030	COG0318	PFAM AMP-dependent synthetase and ligase
DP51_RS02180	COG1566	PFAM secretion protein HlyD family protein
DP51_RS02430	COG0277	FAD linked oxidase domain protein
DP51_RS02480	COG2223	nitrite transmembrane transporter activity
DP51_RS02575	COG3962	Belongs to the TPP enzyme family
DP51_RS02680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP51_RS02680	COG2205	protein histidine kinase activity
DP51_RS02955	COG0366	Alpha amylase catalytic
DP51_RS03505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP51_RS03520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP51_RS03550	COG2010	Cytochrome c
DP51_RS03550	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DP51_RS03860	COG0028	Belongs to the TPP enzyme family
DP51_RS04005	COG2205	protein histidine kinase activity
DP51_RS04025	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DP51_RS04425	COG0583	DNA-binding transcription factor activity
DP51_RS05000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DP51_RS05365	COG1113	amino acid transport
DP51_RS05555	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DP51_RS06205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DP51_RS06310	COG3852	Histidine kinase
DP51_RS06585	COG0183	Belongs to the thiolase family
DP51_RS07200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DP51_RS07235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DP51_RS07310	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP51_RS07310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DP51_RS07380	COG1960	acyl-CoA dehydrogenase activity
DP51_RS07445	COG0587	DNA-directed DNA polymerase activity
DP51_RS07555	COG0793	Belongs to the peptidase S41A family
DP51_RS07620	COG4191	Histidine kinase
DP51_RS07740	COG0737	Belongs to the 5'-nucleotidase family
DP51_RS07745	COG0737	Belongs to the 5'-nucleotidase family
DP51_RS07835	COG0488	(ABC) transporter
DP51_RS08110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP51_RS08540	COG1157	protein secretion by the type III secretion system
DP51_RS08605	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DP51_RS08775	COG1280	lysine exporter protein (LysE YggA)
DP51_RS09265	COG2814	Major facilitator Superfamily
DP51_RS09480	COG1475	DNA binding
DP51_RS09555	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DP51_RS09555	COG0506	proline dehydrogenase activity
DP51_RS09555	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DP51_RS09600	COG1960	acyl-CoA dehydrogenase activity
DP51_RS09725	COG4302	ethanolamine ammonia-lyase activity
DP51_RS10185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DP51_RS10210	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DP51_RS10315	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DP51_RS10440	COG2151	metal-sulfur cluster biosynthetic enzyme
DP51_RS10555	COG0514	ATP-dependent DNA helicase (RecQ)
DP51_RS10650	COG4232	protein-disulfide reductase activity
DP51_RS11295	COG1024	Enoyl-CoA hydratase
DP51_RS11340	COG0318	PFAM AMP-dependent synthetase and ligase
DP51_RS11380	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DP51_RS11595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DP51_RS11595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DP51_RS11600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DP51_RS11600	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DP51_RS11855	COG1466	dna polymerase III delta subunit
DP51_RS12205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DP51_RS12225	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DP51_RS12285	COG3627	carbon phosphorus lyase activity
DP51_RS12295	COG4107	phosphonate C-P lyase system protein PhnK
DP51_RS12335	COG3228	Belongs to the MtfA family
DP51_RS12340	COG0477	Major facilitator Superfamily
DP51_RS12345	COG0789	Transcriptional regulator
DP51_RS12350	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DP51_RS12380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DP51_RS12425	COG0670	Belongs to the BI1 family
DP51_RS12460	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DP51_RS12475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DP51_RS12480	COG0330	HflC and HflK could
DP51_RS12485	COG0330	HflC and HflK could
DP51_RS12505	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DP51_RS12515	COG2183	response to ionizing radiation
DP51_RS12530	COG1199	ATP-dependent helicase activity
DP51_RS12540	COG0564	pseudouridine synthase activity
DP51_RS12545	COG1496	oxidoreductase activity
DP51_RS12550	COG3243	poly(R)-hydroxyalkanoic acid synthase
DP51_RS12555	COG0183	Belongs to the thiolase family
DP51_RS12560	COG1028	Short-chain dehydrogenase reductase Sdr
DP51_RS12580	COG0183	Belongs to the thiolase family
DP51_RS12590	COG0626	cystathionine gamma-synthase activity
DP51_RS12595	COG0560	Phosphoserine phosphatase
DP51_RS12605	COG0390	transport system, permease component
DP51_RS12610	COG1122	ATPase activity
DP51_RS12615	COG2982	Protein involved in outer membrane biogenesis
DP51_RS12620	COG0488	(ABC) transporter
DP51_RS12635	COG2070	2-Nitropropane dioxygenase
DP51_RS12640	COG3047	cAMP biosynthetic process
DP51_RS12650	COG1914	H( )-stimulated, divalent metal cation uptake system
DP51_RS12655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DP51_RS12660	COG3842	ATPase activity
DP51_RS12665	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP51_RS12670	COG1177	transmembrane transport
DP51_RS12675	COG0730	response to heat
DP51_RS12675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP51_RS12700	COG3655	Transcriptional regulator
DP51_RS12725	COG1538	Outer membrane efflux protein
DP51_RS12730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP51_RS12745	COG0038	chloride channel
DP51_RS12750	COG2855	membrane
DP51_RS12770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DP51_RS12780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DP51_RS12785	COG1609	Transcriptional regulator
DP51_RS12880	COG0598	Magnesium transport protein CorA
DP51_RS12885	COG2350	Protein conserved in bacteria
DP51_RS12915	COG3264	Mechanosensitive ion channel
DP51_RS12915	COG1196	nuclear chromosome segregation
DP51_RS12945	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DP51_RS12960	COG4263	nitrous-oxide reductase activity
DP51_RS12980	COG0840	transmembrane signaling receptor activity
DP51_RS12990	COG2376	Dihydroxyacetone kinase
DP51_RS13010	COG0475	glutathione-regulated potassium exporter activity
DP51_RS13070	COG3121	Chaperone
DP51_RS13075	COG3188	usher protein
DP51_RS13105	COG5295	Hep Hag repeat protein
DP51_RS13120	COG2197	response regulator
DP51_RS13180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DP51_RS13185	COG1012	belongs to the aldehyde dehydrogenase family
DP51_RS13200	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP51_RS13210	COG3842	ATPase activity
DP51_RS13225	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP51_RS13235	COG2916	Histone family protein nucleoid-structuring protein H-NS
DP51_RS13265	COG2274	protein secretion by the type I secretion system
DP51_RS13270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DP51_RS13280	COG0859	PFAM glycosyl transferase family 9
DP51_RS13280	COG0457	Tetratricopeptide repeat
DP51_RS13290	COG0529	Catalyzes the synthesis of activated sulfate
DP51_RS13295	COG0745	RESPONSE REGULATOR receiver
DP51_RS13320	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP51_RS13330	COG2986	histidine ammonia-lyase
DP51_RS13340	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DP51_RS13355	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DP51_RS13375	COG1595	DNA-templated transcription, initiation
DP51_RS13400	COG3220	belongs to the UPF0276 family
DP51_RS13410	COG2801	Transposase and inactivated derivatives
DP51_RS13445	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DP51_RS13485	COG5295	Hep Hag repeat protein
DP51_RS13485	COG5295	Hep Hag repeat protein
DP51_RS13515	COG2192	nodulation
DP51_RS13540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DP51_RS13560	COG0165	Argininosuccinate lyase
DP51_RS13565	COG0137	argininosuccinate synthase activity
DP51_RS13580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DP51_RS13590	COG3251	PFAM MbtH domain protein
DP51_RS13605	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP51_RS13610	COG2207	Transcriptional regulator
DP51_RS13615	COG0697	spore germination
DP51_RS13620	COG0835	chemotaxis
DP51_RS13635	COG0318	PFAM AMP-dependent synthetase and ligase
DP51_RS13640	COG0477	Major facilitator Superfamily
DP51_RS13650	COG1732	Glycine betaine
DP51_RS13655	COG1174	glycine betaine transport
DP51_RS13660	COG1125	glycine betaine transport
DP51_RS13665	COG1174	glycine betaine transport
DP51_RS13685	COG2235	arginine
DP51_RS13690	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DP51_RS13710	COG0583	DNA-binding transcription factor activity
DP51_RS13720	COG0625	glutathione transferase activity
DP51_RS13735	COG1846	Transcriptional regulator
DP51_RS13740	COG2807	transmembrane transport
DP51_RS13745	COG1649	PFAM Uncharacterised BCR, COG1649
DP51_RS13765	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DP51_RS13775	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DP51_RS13795	COG3979	chitinase
DP51_RS13805	COG0400	carboxylic ester hydrolase activity
DP51_RS13835	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DP51_RS13860	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DP51_RS13865	COG4774	siderophore transport
DP51_RS13870	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DP51_RS13910	COG1120	ATPase activity
DP51_RS13930	COG1028	Short-chain dehydrogenase reductase Sdr
DP51_RS13935	COG1070	Carbohydrate kinase
DP51_RS13940	COG1063	alcohol dehydrogenase
DP51_RS13945	COG1172	Belongs to the binding-protein-dependent transport system permease family
DP51_RS13955	COG1879	ABC-type sugar transport system periplasmic component
DP51_RS13975	COG2375	cellular response to nickel ion
DP51_RS13975	COG1132	(ABC) transporter
DP51_RS13985	COG3121	Chaperone
DP51_RS13995	COG3539	Fimbrial protein
DP51_RS14010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP51_RS14020	COG1309	transcriptional regulator
DP51_RS14025	COG0765	amino acid transport
DP51_RS14030	COG4597	amino acid ABC transporter
DP51_RS14045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP51_RS14090	COG4964	Belongs to the GSP D family
DP51_RS14110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DP51_RS14115	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DP51_RS14130	COG0477	Major facilitator Superfamily
DP51_RS14135	COG2719	SpoVR family
DP51_RS14140	COG2718	Belongs to the UPF0229 family
DP51_RS14145	COG2766	serine protein kinase
DP51_RS14150	COG0840	transmembrane signaling receptor activity
DP51_RS14155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DP51_RS14160	COG1609	Transcriptional regulator
DP51_RS14165	COG1172	Belongs to the binding-protein-dependent transport system permease family
DP51_RS14170	COG1129	ABC transporter
DP51_RS14175	COG1879	ABC-type sugar transport system periplasmic component
DP51_RS14180	COG0583	DNA-binding transcription factor activity
DP51_RS14185	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DP51_RS14190	COG4208	sulfate ABC transporter
DP51_RS14195	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DP51_RS14200	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DP51_RS14240	COG0701	Predicted permease
DP51_RS14245	COG0667	Aldo Keto reductase
DP51_RS14270	COG1301	dicarboxylic acid transport
DP51_RS14300	COG1116	anion transmembrane transporter activity
DP51_RS14305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DP51_RS14350	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DP51_RS14360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP51_RS14365	COG0765	amino acid transport
DP51_RS14370	COG0673	inositol 2-dehydrogenase activity
DP51_RS14375	COG1802	Transcriptional regulator
DP51_RS14385	COG3023	N-Acetylmuramoyl-L-alanine amidase
DP51_RS14395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DP51_RS14400	COG0557	exoribonuclease II activity
DP51_RS14415	COG0840	transmembrane signaling receptor activity
DP51_RS14440	COG0519	Catalyzes the synthesis of GMP from XMP
DP51_RS14450	COG2814	Major facilitator Superfamily
DP51_RS14460	COG0318	PFAM AMP-dependent synthetase and ligase
DP51_RS14525	COG4964	Belongs to the GSP D family
DP51_RS14580	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DP51_RS14585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DP51_RS14590	COG0508	dehydrogenase complex catalyzes the overall conversion of
DP51_RS14595	COG0567	Dehydrogenase, E1 component
DP51_RS14600	COG1217	gtp-binding protein TYPA
DP51_RS14605	COG1846	Transcriptional regulator
DP51_RS14615	COG1566	PFAM secretion protein HlyD family protein
DP51_RS14620	COG2814	Major facilitator Superfamily
DP51_RS14625	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DP51_RS14640	COG2251	uridine kinase activity
DP51_RS14640	COG0195	Participates in both transcription termination and antitermination
DP51_RS14650	COG1187	pseudouridine synthase activity
DP51_RS14655	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DP51_RS14660	COG0583	DNA-binding transcription factor activity
DP51_RS14700	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DP51_RS14735	COG0776	regulation of translation
DP51_RS14740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DP51_RS14740	COG0072	phenylalanine-tRNA ligase activity
DP51_RS14760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DP51_RS14775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DP51_RS14780	COG0251	oxidation-reduction process
DP51_RS14785	COG2267	carboxylic ester hydrolase activity
DP51_RS14795	COG0583	DNA-binding transcription factor activity
DP51_RS14810	COG1028	Short-chain dehydrogenase reductase Sdr
DP51_RS14845	COG1028	Short-chain dehydrogenase reductase Sdr
DP51_RS14860	COG0477	Major facilitator Superfamily
DP51_RS14875	COG1295	ribonuclease BN
DP51_RS14890	COG0277	FAD linked oxidase domain protein
DP51_RS14905	COG0583	DNA-binding transcription factor activity
DP51_RS14935	COG0840	transmembrane signaling receptor activity
DP51_RS14940	COG2223	nitrite transmembrane transporter activity
DP51_RS14945	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DP51_RS14950	COG0210	DNA helicase
DP51_RS14955	COG0525	valine-tRNA ligase activity
DP51_RS14960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DP51_RS14970	COG5002	protein histidine kinase activity
DP51_RS14980	COG0745	RESPONSE REGULATOR receiver
DP51_RS14990	COG0425	Belongs to the sulfur carrier protein TusA family
DP51_RS14995	COG0673	inositol 2-dehydrogenase activity
DP51_RS15000	COG0673	inositol 2-dehydrogenase activity
DP51_RS15015	COG1172	Belongs to the binding-protein-dependent transport system permease family
DP51_RS15030	COG3962	Belongs to the TPP enzyme family
DP51_RS15040	COG3718	enzyme involved in inositol metabolism
DP51_RS15050	COG0411	ABC transporter
DP51_RS15060	COG0824	Thioesterase
DP51_RS15075	COG2816	NAD+ diphosphatase activity
DP51_RS15085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP51_RS15090	COG0477	Major facilitator Superfamily
DP51_RS15105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DP51_RS15115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DP51_RS15120	COG1051	belongs to the nudix hydrolase family
DP51_RS15140	COG1858	cytochrome C peroxidase
DP51_RS15145	COG3511	phospholipase C
DP51_RS15155	COG1566	PFAM secretion protein HlyD family protein
DP51_RS15160	COG2814	Major facilitator Superfamily
DP51_RS15165	COG1538	Outer membrane efflux protein
DP51_RS15170	COG2197	response regulator
DP51_RS15210	COG0583	DNA-binding transcription factor activity
DP51_RS15215	COG2814	Major facilitator Superfamily
DP51_RS15240	COG1914	H( )-stimulated, divalent metal cation uptake system
DP51_RS15395	COG0457	Tetratricopeptide repeat
DP51_RS15395	COG0859	PFAM glycosyl transferase family 9
DP51_RS15445	COG0745	RESPONSE REGULATOR receiver
DP51_RS15450	COG0583	DNA-binding transcription factor activity
DP51_RS15485	COG0366	Alpha amylase catalytic
DP51_RS15490	COG0366	Alpha amylase catalytic
DP51_RS15510	COG1640	4-alpha-glucanotransferase
DP51_RS15570	COG0582	viral genome integration into host DNA
DP51_RS15595	COG4942	peptidase
DP51_RS15600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DP51_RS15610	COG0534	Mate efflux family protein
DP51_RS15675	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DP51_RS15685	COG0745	RESPONSE REGULATOR receiver
DP51_RS15700	COG0581	inorganic phosphate transmembrane transporter activity
DP51_RS15705	COG0573	inorganic phosphate transmembrane transporter activity
DP51_RS15710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DP51_RS15720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DP51_RS15725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DP51_RS15735	COG1534	Rna-binding protein
DP51_RS15745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DP51_RS15750	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DP51_RS15760	COG0505	Belongs to the CarA family
DP51_RS15785	COG1388	LysM domain
DP51_RS15785	COG0741	lytic transglycosylase activity
DP51_RS15790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DP51_RS15795	COG2226	methyltransferase
DP51_RS15800	COG0328	RNA-DNA hybrid ribonuclease activity
DP51_RS15805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DP51_RS15815	COG0477	Major facilitator Superfamily
DP51_RS15840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DP51_RS15850	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DP51_RS15870	COG3052	prosthetic group binding
DP51_RS15890	COG0583	DNA-binding transcription factor activity
DP51_RS15895	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP51_RS15900	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DP51_RS15930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DP51_RS15960	COG0583	DNA-binding transcription factor activity
DP51_RS15980	COG1522	sequence-specific DNA binding
DP51_RS16025	COG1609	Transcriptional regulator
DP51_RS16030	COG1840	ABC-type Fe3 transport system, periplasmic component
DP51_RS16035	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DP51_RS16050	COG1177	transmembrane transport
DP51_RS16055	COG3842	ATPase activity
DP51_RS16060	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DP51_RS16080	COG2814	Major facilitator Superfamily
DP51_RS16085	COG0697	spore germination
DP51_RS16095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DP51_RS16100	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
DP51_RS16140	COG2200	EAL domain
DP51_RS16150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DP51_RS16155	COG1074	ATP-dependent DNA helicase activity
DP51_RS16160	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DP51_RS16170	COG1289	transmembrane transporter activity
DP51_RS16185	COG1840	ABC-type Fe3 transport system, periplasmic component
DP51_RS16190	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP51_RS16195	COG3842	ATPase activity
DP51_RS16200	COG1522	sequence-specific DNA binding
DP51_RS16215	COG1959	2 iron, 2 sulfur cluster binding
DP51_RS16240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP51_RS16245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP51_RS16280	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DP51_RS16295	COG2010	Cytochrome c
DP51_RS16295	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DP51_RS16300	COG2863	cytochrome
DP51_RS16320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DP51_RS16330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DP51_RS16345	COG0006	proline dipeptidase activity
DP51_RS16395	COG2866	Carboxypeptidase
DP51_RS16410	COG0436	Aminotransferase
DP51_RS16420	COG1024	Enoyl-CoA hydratase
DP51_RS16425	COG0588	phosphoglycerate mutase activity
DP51_RS16435	COG1960	acyl-CoA dehydrogenase activity
DP51_RS16455	COG1012	belongs to the aldehyde dehydrogenase family
DP51_RS16455	COG2030	dehydratase
DP51_RS16460	COG1960	acyl-CoA dehydrogenase activity
DP51_RS16465	COG1960	acyl-CoA dehydrogenase activity
DP51_RS16485	COG1007	ATP synthesis coupled electron transport
DP51_RS16520	COG1034	ATP synthesis coupled electron transport
DP51_RS16530	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DP51_RS16565	COG0149	triose-phosphate isomerase activity
DP51_RS16570	COG4221	oxidoreductase activity
DP51_RS16570	COG0604	alcohol dehydrogenase
DP51_RS16570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DP51_RS16570	COG3321	synthase
DP51_RS16585	COG0683	leucine binding
DP51_RS16600	COG0288	reversible hydration of carbon dioxide
DP51_RS16605	COG0659	secondary active sulfate transmembrane transporter activity
DP51_RS16615	COG1183	phosphatidylcholine synthase activity
DP51_RS16635	COG0028	Belongs to the TPP enzyme family
DP51_RS16665	COG0438	transferase activity, transferring glycosyl groups
DP51_RS16685	COG1028	Short-chain dehydrogenase reductase Sdr
DP51_RS16690	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DP51_RS16700	COG0154	amidase activity
DP51_RS16710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DP51_RS16740	COG0745	RESPONSE REGULATOR receiver
DP51_RS16745	COG2205	protein histidine kinase activity
DP51_RS16760	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DP51_RS16765	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DP51_RS16785	COG1028	Short-chain dehydrogenase reductase Sdr
DP51_RS16800	COG0151	Belongs to the GarS family
DP51_RS16815	COG0799	negative regulation of ribosome biogenesis
DP51_RS16835	COG2233	PERMEase
DP51_RS16870	COG1595	DNA-templated transcription, initiation
DP51_RS16875	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DP51_RS16905	COG0859	PFAM glycosyl transferase family 9
DP51_RS16910	COG0438	transferase activity, transferring glycosyl groups
DP51_RS16950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DP51_RS16955	COG0513	Belongs to the DEAD box helicase family
DP51_RS16990	COG1674	ftsk spoiiie
DP51_RS16995	COG2706	6-phosphogluconolactonase activity
DP51_RS17000	COG3387	PFAM Glycoside hydrolase 15-related
DP51_RS17010	COG1309	transcriptional regulator
DP51_RS17015	COG2878	Part of a membrane complex involved in electron transport
DP51_RS17020	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DP51_RS17055	COG3135	benzoate transporter
DP51_RS17070	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DP51_RS17085	COG4106	trans-aconitate 2-methyltransferase activity
DP51_RS17105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DP51_RS17115	COG0697	spore germination
DP51_RS17120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DP51_RS17155	COG0477	Major facilitator Superfamily
DP51_RS17160	COG0583	DNA-binding transcription factor activity
DP51_RS17170	COG0583	DNA-binding transcription factor activity
DP51_RS17195	COG0488	(ABC) transporter
DP51_RS17205	COG1773	rubredoxin
DP51_RS17250	COG0582	viral genome integration into host DNA
DP51_RS17315	COG2801	Transposase and inactivated derivatives
DP51_RS17330	COG2963	transposase activity
DP51_RS17385	COG1881	PFAM PEBP family protein
DP51_RS17390	COG2814	Major facilitator Superfamily
DP51_RS17410	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DP51_RS17430	COG1116	anion transmembrane transporter activity
DP51_RS17435	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP51_RS17460	COG1741	Belongs to the pirin family
DP51_RS17475	COG4215	(ABC) transporter
DP51_RS17495	COG0347	Belongs to the P(II) protein family
DP51_RS17510	COG1472	Belongs to the glycosyl hydrolase 3 family
DP51_RS17515	COG2827	Endonuclease containing a URI domain
DP51_RS17520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DP51_RS17535	COG2271	Major facilitator Superfamily
DP51_RS17565	COG2226	methyltransferase
DP51_RS17600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DP51_RS17625	COG0489	protein tyrosine kinase activity
DP51_RS17630	COG3047	cAMP biosynthetic process
DP51_RS17630	COG2885	chlorophyll binding
DP51_RS17650	COG2911	Protein conserved in bacteria
DP51_RS17655	COG0729	surface antigen
DP51_RS17665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DP51_RS17680	COG0489	protein tyrosine kinase activity
DP51_RS17685	COG2259	Doxx family
DP51_RS17690	COG1492	cobalamin metabolic process
DP51_RS17700	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DP51_RS17710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DP51_RS17725	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DP51_RS17730	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DP51_RS17735	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DP51_RS17745	COG4206	TonB-dependent receptor
DP51_RS17775	COG0583	DNA-binding transcription factor activity
DP51_RS17785	COG4654	Cytochrome c, class I
DP51_RS17805	COG0795	lipopolysaccharide-transporting ATPase activity
DP51_RS17820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DP51_RS17820	COG1648	precorrin-2 dehydrogenase activity
DP51_RS17825	COG2895	sulfate adenylyltransferase (ATP) activity
DP51_RS17835	COG0175	sulfate reduction
DP51_RS17850	COG0583	DNA-binding transcription factor activity
DP51_RS17860	COG0582	viral genome integration into host DNA
DP51_RS17920	COG1396	sequence-specific DNA binding
DP51_RS17925	COG0235	Class ii aldolase
DP51_RS17930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DP51_RS17935	COG2258	MOSC domain
DP51_RS17940	COG2267	carboxylic ester hydrolase activity
DP51_RS17950	COG0583	DNA-binding transcription factor activity
DP51_RS17960	COG1187	pseudouridine synthase activity
DP51_RS17975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DP51_RS17975	COG0543	2 iron, 2 sulfur cluster binding
DP51_RS17980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DP51_RS17985	COG0456	acetyltransferase
DP51_RS18020	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DP51_RS18025	COG1047	Peptidyl-prolyl cis-trans
DP51_RS18045	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DP51_RS18070	COG3264	Mechanosensitive ion channel
DP51_RS18070	COG1511	domain protein
DP51_RS18075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DP51_RS18075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DP51_RS18080	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DP51_RS18085	COG0196	riboflavin kinase activity
DP51_RS18090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DP51_RS18120	COG1113	amino acid transport
DP51_RS18125	COG0542	response to heat
DP51_RS18135	COG1278	Cold shock
DP51_RS18160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DP51_RS18170	COG0656	L-ascorbic acid biosynthetic process
DP51_RS18175	COG2188	Transcriptional regulator
DP51_RS18190	COG2814	Major facilitator Superfamily
DP51_RS18235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DP51_RS18240	COG1570	exodeoxyribonuclease VII activity
DP51_RS18245	COG1663	tetraacyldisaccharide 4'-kinase activity
DP51_RS18275	COG0728	peptidoglycan biosynthetic process
DP51_RS18290	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DP51_RS18295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DP51_RS18305	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DP51_RS18310	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DP51_RS18315	COG0318	PFAM AMP-dependent synthetase and ligase
DP51_RS18320	COG4974	Belongs to the 'phage' integrase family
DP51_RS18330	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DP51_RS18335	COG0802	atpase or kinase
DP51_RS18340	COG0860	N-Acetylmuramoyl-L-alanine amidase
DP51_RS18350	COG1741	Belongs to the pirin family
DP51_RS18355	COG3118	belongs to the thioredoxin family
DP51_RS18360	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DP51_RS18370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DP51_RS18385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DP51_RS18395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DP51_RS18400	COG1522	sequence-specific DNA binding
DP51_RS18420	COG2271	Major facilitator Superfamily
DP51_RS18435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DP51_RS18440	COG1012	belongs to the aldehyde dehydrogenase family
DP51_RS18450	COG0583	DNA-binding transcription factor activity
DP51_RS18455	COG0246	Mannitol dehydrogenase
DP51_RS18460	COG1070	Carbohydrate kinase
DP51_RS18465	COG2390	Transcriptional regulator
DP51_RS18480	COG0583	DNA-binding transcription factor activity
DP51_RS18490	COG3842	ATPase activity
DP51_RS18495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DP51_RS18505	COG1175	transmembrane transport
DP51_RS18520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DP51_RS18530	COG0735	belongs to the Fur family
DP51_RS18540	COG1121	(ABC) transporter
DP51_RS18545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DP51_RS18550	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DP51_RS18565	COG1070	Carbohydrate kinase
DP51_RS18570	COG2233	PERMEase
DP51_RS18585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP51_RS18590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DP51_RS18615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP51_RS18645	COG0009	L-threonylcarbamoyladenylate synthase
DP51_RS18650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DP51_RS18655	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DP51_RS18660	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DP51_RS18670	COG0469	pyruvate kinase activity
DP51_RS18675	COG0126	phosphoglycerate kinase activity
DP51_RS18700	COG0859	PFAM glycosyl transferase family 9
DP51_RS18710	COG0429	hydrolase of the alpha beta-hydrolase fold
DP51_RS18720	COG4783	chaperone-mediated protein folding
DP51_RS18740	COG3307	-O-antigen
DP51_RS18745	COG4969	Belongs to the N-Me-Phe pilin family
DP51_RS18750	COG0861	Integral membrane protein TerC family
DP51_RS18755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DP51_RS18770	COG2137	regulation of response to DNA damage stimulus
DP51_RS18775	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DP51_RS18860	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DP51_RS18915	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DP51_RS18945	COG0583	DNA-binding transcription factor activity
DP51_RS18990	COG0784	Response regulator, receiver
DP51_RS18990	COG5002	protein histidine kinase activity
DP51_RS18995	COG0583	DNA-binding transcription factor activity
DP51_RS19035	COG0028	Belongs to the TPP enzyme family
DP51_RS19040	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DP51_RS19045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DP51_RS19115	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DP51_RS19120	COG0583	DNA-binding transcription factor activity
DP51_RS19140	COG0840	transmembrane signaling receptor activity
DP51_RS19180	COG4948	Mandelate Racemase Muconate Lactonizing
DP51_RS19200	COG0513	Belongs to the DEAD box helicase family
DP51_RS19240	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DP51_RS19245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DP51_RS19255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DP51_RS19260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DP51_RS19265	COG0367	asparagine synthase
DP51_RS19280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DP51_RS19290	COG1396	sequence-specific DNA binding
DP51_RS19295	COG2814	Major facilitator Superfamily
DP51_RS19300	COG0583	DNA-binding transcription factor activity
DP51_RS19310	COG1702	phosphate starvation-inducible protein PhoH
DP51_RS19320	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DP51_RS19330	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DP51_RS19335	COG0752	glycyl-tRNA synthetase alpha subunit
DP51_RS19340	COG0751	glycine-tRNA ligase activity
DP51_RS19345	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DP51_RS19350	COG0204	Acyl-transferase
DP51_RS19375	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DP51_RS19395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DP51_RS19405	COG5265	(ABC) transporter
DP51_RS19420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DP51_RS19425	COG1024	Enoyl-CoA hydratase
DP51_RS19430	COG0183	Belongs to the thiolase family
DP51_RS19435	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP51_RS19435	COG1024	Enoyl-CoA hydratase
DP51_RS19440	COG1960	acyl-CoA dehydrogenase activity
DP51_RS19455	COG0494	nUDIX hydrolase
DP51_RS19520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DP51_RS19530	COG0251	oxidation-reduction process
DP51_RS19535	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DP51_RS19560	COG0477	Major facilitator Superfamily
DP51_RS19595	COG1596	polysaccharide export
DP51_RS19600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DP51_RS19615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DP51_RS19625	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DP51_RS19645	COG2204	response regulator
DP51_RS19680	COG5002	protein histidine kinase activity
DP51_RS19680	COG5001	Diguanylate cyclase
DP51_RS19685	COG0235	Class ii aldolase
DP51_RS19740	COG0142	geranyltranstransferase activity
DP51_RS19810	COG0629	single-stranded DNA binding
DP51_RS19815	COG2814	Major facilitator Superfamily
DP51_RS19840	COG1280	lysine exporter protein (LysE YggA)
DP51_RS19860	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DP51_RS19875	COG1137	ATPase activity
DP51_RS19880	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DP51_RS19885	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DP51_RS19910	COG1194	a g-specific adenine glycosylase
DP51_RS19925	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DP51_RS19940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DP51_RS19960	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DP51_RS19970	COG0742	ribosomal rna small subunit methyltransferase
DP51_RS19980	COG0625	glutathione transferase activity
DP51_RS19990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DP51_RS20000	COG0243	molybdopterin cofactor binding
DP51_RS20005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DP51_RS20015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DP51_RS20025	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DP51_RS20030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DP51_RS20045	COG1294	oxidase, subunit
DP51_RS20065	COG2190	(PTS) system
DP51_RS20065	COG1263	PTS System
DP51_RS20065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP51_RS20070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP51_RS20070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DP51_RS20075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DP51_RS20080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DP51_RS20085	COG2188	Transcriptional regulator
DP51_RS20090	COG0583	DNA-binding transcription factor activity
DP51_RS20135	COG0318	PFAM AMP-dependent synthetase and ligase
DP51_RS20145	COG1960	acyl-CoA dehydrogenase activity
DP51_RS20155	COG2226	methyltransferase
DP51_RS20190	COG2814	Major facilitator Superfamily
DP51_RS20200	COG0587	DNA-directed DNA polymerase activity
DP51_RS20215	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DP51_RS20235	COG0840	transmembrane signaling receptor activity
DP51_RS20245	COG1999	signal sequence binding
DP51_RS20255	COG1612	heme a metabolic process
DP51_RS20285	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DP51_RS20295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DP51_RS20310	COG2226	methyltransferase
DP51_RS20315	COG1040	competence protein
DP51_RS20325	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DP51_RS20345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DP51_RS20355	COG0793	Belongs to the peptidase S41A family
DP51_RS20360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DP51_RS20365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DP51_RS20370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP51_RS20380	COG0189	ligase activity
DP51_RS20390	COG0004	ammonium transporteR
DP51_RS20400	COG2960	long-chain fatty acid transporting porin activity
DP51_RS20430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DP51_RS20440	COG4191	Histidine kinase
DP51_RS20450	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DP51_RS20460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DP51_RS20465	COG1960	acyl-CoA dehydrogenase activity
DP51_RS20470	COG1960	acyl-CoA dehydrogenase activity
DP51_RS20475	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP51_RS20475	COG1024	Enoyl-CoA hydratase
DP51_RS20480	COG0583	DNA-binding transcription factor activity
DP51_RS20520	COG0583	DNA-binding transcription factor activity
DP51_RS20525	COG2921	Belongs to the UPF0250 family
DP51_RS20535	COG1686	Belongs to the peptidase S11 family
DP51_RS20565	COG1127	ABC transporter
DP51_RS20570	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DP51_RS20575	COG0737	Belongs to the 5'-nucleotidase family
DP51_RS20590	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DP51_RS20600	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DP51_RS20620	COG1024	Enoyl-CoA hydratase
DP51_RS20670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DP51_RS20675	COG4221	oxidoreductase activity
DP51_RS20680	COG1028	Short-chain dehydrogenase reductase Sdr
DP51_RS20695	COG0747	negative chemotaxis
DP51_RS20700	COG0488	(ABC) transporter
DP51_RS20715	COG0288	reversible hydration of carbon dioxide
DP51_RS20720	COG0183	Belongs to the thiolase family
DP51_RS20730	COG3012	SEC-C Motif Domain Protein
DP51_RS20750	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DP51_RS20775	COG1785	Belongs to the alkaline phosphatase family
DP51_RS20785	COG2200	EAL domain
DP51_RS20785	COG2199	diguanylate cyclase activity
DP51_RS20790	COG0025	NhaP-type Na H and K H
DP51_RS20820	COG2204	response regulator
DP51_RS20850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DP51_RS20865	COG1999	signal sequence binding
DP51_RS20900	COG3511	phospholipase C
DP51_RS20920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DP51_RS20950	COG0596	Alpha beta hydrolase
DP51_RS20960	COG0583	DNA-binding transcription factor activity
DP51_RS20965	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP51_RS20980	COG0840	transmembrane signaling receptor activity
DP51_RS20985	COG1609	Transcriptional regulator
DP51_RS21035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DP51_RS21055	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP51_RS21060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DP51_RS21080	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DP51_RS21085	COG1704	LemA family
DP51_RS21175	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP51_RS21185	COG2824	Alkylphosphonate utilization operon protein PhnA
DP51_RS21205	COG0583	DNA-binding transcription factor activity
DP51_RS21210	COG2233	PERMEase
DP51_RS21215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DP51_RS21225	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DP51_RS21235	COG1706	bacterial-type flagellum-dependent cell motility
DP51_RS21240	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DP51_RS21255	COG1749	Flagellar hook protein flgE
DP51_RS21260	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DP51_RS21265	COG1558	bacterial-type flagellum-dependent cell motility
DP51_RS21270	COG1815	bacterial-type flagellum-dependent cell motility
DP51_RS21280	COG2747	anti-sigma28 factor FlgM
DP51_RS21310	COG0741	lytic transglycosylase activity
DP51_RS21315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DP51_RS21325	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DP51_RS21330	COG1984	allophanate hydrolase subunit 2
DP51_RS21360	COG4608	Belongs to the ABC transporter superfamily
DP51_RS21365	COG0444	Belongs to the ABC transporter superfamily
DP51_RS21370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DP51_RS21375	COG0601	transmembrane transport
DP51_RS21380	COG0747	negative chemotaxis
DP51_RS21395	COG0579	oxidoreductase
DP51_RS21410	COG3568	Endonuclease Exonuclease Phosphatase
DP51_RS21415	COG1280	lysine exporter protein (LysE YggA)
DP51_RS21435	COG0531	amino acid
DP51_RS21450	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DP51_RS21510	COG1960	acyl-CoA dehydrogenase activity
DP51_RS21525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DP51_RS21535	COG2814	Major facilitator Superfamily
DP51_RS21550	COG0667	Aldo Keto reductase
DP51_RS21575	COG1560	Kdo2-lipid A biosynthetic process
DP51_RS21590	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DP51_RS21600	COG0523	cobalamin synthesis protein
DP51_RS21620	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DP51_RS21645	COG1309	transcriptional regulator
DP51_RS21660	COG2814	Major facilitator Superfamily
DP51_RS21670	COG2207	Transcriptional regulator
DP51_RS21675	COG1064	alcohol dehydrogenase
DP51_RS21680	COG0708	Exodeoxyribonuclease III
DP51_RS21685	COG2326	polyphosphate kinase activity
DP51_RS21705	COG1077	Cell shape determining protein MreB Mrl
DP51_RS21720	COG0768	penicillin binding
DP51_RS21725	COG0772	Belongs to the SEDS family
DP51_RS21740	COG0720	synthase
DP51_RS21745	COG0602	queuosine metabolic process
DP51_RS21760	COG2204	response regulator
DP51_RS21765	COG5000	phosphorelay sensor kinase activity
DP51_RS21775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DP51_RS21775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DP51_RS21795	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DP51_RS21800	COG0242	peptide deformylase activity
DP51_RS21805	COG0758	DNA mediated transformation
DP51_RS21820	COG0583	DNA-binding transcription factor activity
DP51_RS21825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DP51_RS21860	COG4695	Portal protein
DP51_RS21865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DP51_RS21880	COG0583	DNA-binding transcription factor activity
DP51_RS21900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DP51_RS21915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DP51_RS21915	COG2169	Transcriptional regulator
DP51_RS21935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DP51_RS22010	COG0582	viral genome integration into host DNA
DP51_RS22050	COG0592	DNA-directed DNA polymerase activity
DP51_RS22065	COG0753	catalase activity
DP51_RS22105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DP51_RS22110	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP51_RS22110	COG1024	Enoyl-CoA hydratase
DP51_RS22115	COG0183	Belongs to the thiolase family
DP51_RS22120	COG1960	acyl-CoA dehydrogenase activity
DP51_RS22145	COG1695	Transcriptional regulator
DP51_RS22205	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP51_RS22225	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP51_RS22240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DP51_RS22250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DP51_RS22265	COG0789	Transcriptional regulator
DP51_RS22275	COG1987	bacterial-type flagellum assembly
DP51_RS22290	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DP51_RS22305	COG1346	cytolysis
DP51_RS22315	COG0583	DNA-binding transcription factor activity
DP51_RS22320	COG2814	Major facilitator Superfamily
DP51_RS22325	COG1846	Transcriptional regulator
DP51_RS22370	COG2165	general secretion pathway protein
DP51_RS22385	COG1459	type II secretion system
DP51_RS22405	COG0523	cobalamin synthesis protein
DP51_RS22435	COG0519	Catalyzes the synthesis of GMP from XMP
DP51_RS22435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DP51_RS22440	COG1902	pentaerythritol trinitrate reductase activity
DP51_RS22455	COG0642	Histidine kinase
DP51_RS22475	COG3186	Phenylalanine-4-hydroxylase
DP51_RS22480	COG1522	sequence-specific DNA binding
DP51_RS22490	COG0583	DNA-binding transcription factor activity
DP51_RS22500	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DP51_RS22520	COG0559	Belongs to the binding-protein-dependent transport system permease family
DP51_RS22570	COG1192	Involved in chromosome partitioning
DP51_RS22575	COG1475	DNA binding
DP51_RS22580	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DP51_RS22590	COG0356	it plays a direct role in the translocation of protons across the membrane
DP51_RS22630	COG0318	PFAM AMP-dependent synthetase and ligase
DP51_RS22635	COG1832	CoA-binding protein
DP51_RS22650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DP51_RS22660	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DP51_RS22660	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DP51_RS22660	COG0506	proline dehydrogenase activity
DP51_RS22675	COG1960	acyl-CoA dehydrogenase activity
DP51_RS22685	COG0436	Aminotransferase
DP51_RS22705	COG0277	FAD linked oxidase domain protein
DP51_RS22715	COG0789	Transcriptional regulator
DP51_RS22730	COG0668	transmembrane transport
DP51_RS22750	COG0531	amino acid
DP51_RS22755	COG4303	Ethanolamine ammonia lyase large subunit
DP51_RS22760	COG4302	ethanolamine ammonia-lyase activity
DP51_RS22770	COG1012	belongs to the aldehyde dehydrogenase family
DP51_RS22795	COG1760	l-serine dehydratase
DP51_RS22810	COG0509	glycine decarboxylation via glycine cleavage system
DP51_RS22825	COG0673	inositol 2-dehydrogenase activity
DP51_RS22840	COG0210	DNA helicase
DP51_RS22845	COG3245	cytochrome
DP51_RS22855	COG0582	viral genome integration into host DNA
DP51_RS23080	COG4695	Portal protein
DP51_RS23110	COG3397	chitin binding
DP51_RS23130	COG2267	carboxylic ester hydrolase activity
DP51_RS23185	COG1028	Short-chain dehydrogenase reductase Sdr
DP51_RS23200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DP51_RS23235	COG0519	Catalyzes the synthesis of GMP from XMP
DP51_RS23245	COG0561	phosphatase activity
DP51_RS23250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DP51_RS23260	COG0438	transferase activity, transferring glycosyl groups
DP51_RS23280	COG1360	Flagellar Motor Protein
DP51_RS23285	COG2201	protein-glutamate methylesterase activity
DP51_RS23305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DP51_RS23315	COG2201	protein-glutamate methylesterase activity
DP51_RS23320	COG0745	RESPONSE REGULATOR receiver
DP51_RS23325	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DP51_RS23345	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DP51_RS23350	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DP51_RS23375	COG1950	PFAM Membrane protein of
DP51_RS23380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DP51_RS23395	COG2070	2-Nitropropane dioxygenase
DP51_RS23420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DP51_RS23425	COG1522	sequence-specific DNA binding
DP51_RS23435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DP51_RS23455	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DP51_RS23460	COG2823	Periplasmic or secreted lipoprotein
DP51_RS23475	COG1113	amino acid transport
DP51_RS23505	COG2084	Dehydrogenase
DP51_RS23510	COG1280	lysine exporter protein (LysE YggA)
DP51_RS23515	COG2814	Major facilitator Superfamily
DP51_RS23520	COG0583	DNA-binding transcription factor activity
DP51_RS23525	COG3047	cAMP biosynthetic process
DP51_RS23540	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DP51_RS23550	COG1881	PFAM PEBP family protein
DP51_RS23555	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DP51_RS23560	COG0281	malic enzyme
DP51_RS23560	COG0280	phosphate acetyltransferase
DP51_RS23580	COG1522	sequence-specific DNA binding
DP51_RS23600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DP51_RS23605	COG2151	metal-sulfur cluster biosynthetic enzyme
DP51_RS23610	COG3396	Phenylacetate-CoA oxygenase
DP51_RS23615	COG3460	Phenylacetate-CoA oxygenase
DP51_RS23620	COG3396	Phenylacetate-CoA oxygenase
DP51_RS23680	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DP51_RS23720	COG0514	ATP-dependent DNA helicase (RecQ)
DP51_RS23850	COG0201	protein transport
DP51_RS23895	COG4232	protein-disulfide reductase activity
DP51_RS23915	COG1333	cytochrome c biogenesis protein
DP51_RS23920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DP51_RS23925	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DP51_RS23930	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DP51_RS23990	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DP51_RS24000	COG1175	transmembrane transport
DP51_RS24005	COG0395	ABC-type sugar transport system, permease component
DP51_RS24015	COG0584	glycerophosphoryl diester phosphodiesterase
DP51_RS24030	COG0067	glutamate synthase
DP51_RS24030	COG0069	glutamate synthase activity
DP51_RS24030	COG0070	glutamate synthase
DP51_RS24040	COG1115	amino acid carrier protein
DP51_RS24050	COG4178	(ABC) transporter
DP51_RS24075	COG1127	ABC transporter
DP51_RS24080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DP51_RS24085	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DP51_RS24105	COG1131	(ABC) transporter
DP51_RS24110	COG0842	Transport permease protein
DP51_RS24130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DP51_RS24135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DP51_RS24145	COG2095	MarC family integral membrane protein
DP51_RS24195	COG0805	protein transport
DP51_RS24205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP51_RS24210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DP51_RS24215	COG0723	plastoquinol--plastocyanin reductase activity
DP51_RS24220	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DP51_RS24225	COG2857	Cytochrome c1
DP51_RS24230	COG0625	glutathione transferase activity
DP51_RS24235	COG2969	positive regulation of protein catabolic process
DP51_RS24250	COG4695	Portal protein
DP51_RS24255	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DP51_RS24260	COG3657	addiction module killer protein
DP51_RS24400	COG0308	aminopeptidase N
DP51_RS24445	COG0443	Heat shock 70 kDa protein
DP51_RS24450	COG1278	Cold shock
DP51_RS24455	COG0531	amino acid
DP51_RS24460	COG3384	dioxygenase
DP51_RS24470	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DP51_RS24475	COG2890	protein-(glutamine-N5) methyltransferase activity
DP51_RS24505	COG0006	proline dipeptidase activity
DP51_RS24515	COG1335	isochorismatase
DP51_RS24525	COG0488	(ABC) transporter
DP51_RS24540	COG0584	glycerophosphoryl diester phosphodiesterase
DP51_RS24570	COG0012	GTP binding
DP51_RS24585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DP51_RS24590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DP51_RS24605	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DP51_RS24625	COG0512	Glutamine amidotransferase of anthranilate synthase
DP51_RS24635	COG0546	phosphoglycolate phosphatase activity
DP51_RS24640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DP51_RS24645	COG2967	ApaG domain
DP51_RS24655	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DP51_RS24665	COG2050	protein possibly involved in aromatic compounds catabolism
DP51_RS24670	COG1024	Enoyl-CoA hydratase
DP51_RS24675	COG0183	Belongs to the thiolase family
DP51_RS24685	COG1024	Enoyl-CoA hydratase
DP51_RS24715	COG0243	molybdopterin cofactor binding
DP51_RS24720	COG0318	PFAM AMP-dependent synthetase and ligase
DP51_RS24725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP51_RS24745	COG3116	cell division
DP51_RS24755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DP51_RS24760	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DP51_RS24795	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DP51_RS24810	COG0678	peroxiredoxin activity
DP51_RS24835	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DP51_RS24845	COG0494	nUDIX hydrolase
DP51_RS24850	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DP51_RS24865	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DP51_RS24875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DP51_RS24880	COG4536	flavin adenine dinucleotide binding
DP51_RS24890	COG0142	geranyltranstransferase activity
DP51_RS24935	COG2095	MarC family integral membrane protein
DP51_RS24940	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DP51_RS24945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DP51_RS24985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DP51_RS24990	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DP51_RS25005	COG0439	Biotin carboxylase
DP51_RS25010	COG0511	ligase activity, forming carbon-carbon bonds
DP51_RS25015	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DP51_RS25020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DP51_RS25030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DP51_RS25035	COG3150	esterase
DP51_RS25040	COG0557	exoribonuclease II activity
DP51_RS25045	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DP51_RS25050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DP51_RS25065	COG1414	Transcriptional regulator
DP51_RS25070	COG3734	2-keto-3-deoxy-galactonokinase
DP51_RS25080	COG1028	Short-chain dehydrogenase reductase Sdr
DP51_RS25095	COG1172	Belongs to the binding-protein-dependent transport system permease family
DP51_RS25100	COG1028	Short-chain dehydrogenase reductase Sdr
DP51_RS25110	COG0284	orotidine-5'-phosphate decarboxylase activity
DP51_RS25120	COG1546	Belongs to the CinA family
DP51_RS25125	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DP51_RS25155	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DP51_RS25165	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DP51_RS25170	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DP51_RS25175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DP51_RS25180	COG2814	Major facilitator Superfamily
DP51_RS25195	COG0583	DNA-binding transcription factor activity
DP51_RS25205	COG1301	dicarboxylic acid transport
DP51_RS25210	COG4266	Belongs to the allantoicase family
DP51_RS25215	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DP51_RS25220	COG0735	belongs to the Fur family
DP51_RS25225	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DP51_RS25255	COG1466	dna polymerase III delta subunit
DP51_RS25260	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DP51_RS25265	COG1981	membrane
DP51_RS25270	COG0837	glucose binding
DP51_RS25270	COG1737	Transcriptional regulator
DP51_RS25280	COG0800	Aldolase
DP51_RS25300	COG2223	nitrite transmembrane transporter activity
DP51_RS25305	COG0583	DNA-binding transcription factor activity
DP51_RS25310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DP51_RS25315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP51_RS25320	COG0765	amino acid transport
DP51_RS25325	COG0765	amino acid transport
DP51_RS25330	COG1126	abc transporter atp-binding protein
DP51_RS25360	COG0121	glutamine amidotransferase
DP51_RS25365	COG0418	dihydroorotase activity
DP51_RS25395	COG1917	Cupin 2, conserved barrel domain protein
DP51_RS25395	COG4977	sequence-specific DNA binding
DP51_RS25400	COG0625	glutathione transferase activity
DP51_RS25405	COG0625	glutathione transferase activity
DP51_RS25415	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DP51_RS25425	COG0588	phosphoglycerate mutase activity
DP51_RS25465	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DP51_RS25470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DP51_RS25475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DP51_RS25480	COG0006	proline dipeptidase activity
DP51_RS25485	COG0625	glutathione transferase activity
DP51_RS25490	COG0069	glutamate synthase activity
DP51_RS25560	COG3008	intermembrane lipid transfer
DP51_RS25560	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DP51_RS25565	COG2995	paraquat-inducible protein a
DP51_RS25585	COG2353	YceI-like domain
DP51_RS25590	COG2353	YceI-like domain
DP51_RS25600	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DP51_RS25605	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DP51_RS25610	COG1862	Preprotein translocase
DP51_RS25615	COG0343	queuine tRNA-ribosyltransferase activity
DP51_RS25625	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DP51_RS25645	COG0783	Belongs to the Dps family
DP51_RS25665	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DP51_RS25670	COG2188	Transcriptional regulator
DP51_RS25675	COG3624	Phosphonate C-P lyase system protein PhnG
DP51_RS25685	COG3626	phosphonate metabolism
DP51_RS25690	COG3627	carbon phosphorus lyase activity
DP51_RS25695	COG4107	phosphonate C-P lyase system protein PhnK
DP51_RS25700	COG4778	phosphonate C-P lyase system protein PhnL
DP51_RS25705	COG3454	Phosphonate metabolism
DP51_RS25710	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DP51_RS25715	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DP51_RS25720	COG3639	organic phosphonate transmembrane transporter activity
DP51_RS25740	COG0247	lactate metabolic process
DP51_RS25745	COG0277	FAD linked oxidase domain protein
DP51_RS25750	COG0277	FAD linked oxidase domain protein
DP51_RS25755	COG0277	FAD linked oxidase domain protein
DP51_RS25760	COG2096	Adenosyltransferase
DP51_RS25765	COG1017	nitric oxide dioxygenase activity
DP51_RS25765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DP51_RS25770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DP51_RS25775	COG0312	modulator of DNA gyrase
DP51_RS25780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DP51_RS25785	COG3164	Protein of unknown function
DP51_RS25790	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DP51_RS25795	COG0497	DNA recombination
DP51_RS25800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DP51_RS25840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DP51_RS25850	COG1428	Deoxynucleoside kinase
DP51_RS25855	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DP51_RS25860	COG0617	tRNA 3'-terminal CCA addition
DP51_RS25870	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DP51_RS25890	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DP51_RS25895	COG0586	Pfam SNARE associated Golgi protein
DP51_RS25995	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DP51_RS26010	COG1368	sulfuric ester hydrolase activity
DP51_RS26020	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DP51_RS26025	COG0156	8-amino-7-oxononanoate synthase activity
DP51_RS26065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DP51_RS26070	COG3206	protein involved in exopolysaccharide biosynthesis
DP51_RS26070	COG0489	protein tyrosine kinase activity
DP51_RS26080	COG3562	capsule polysaccharide
DP51_RS26085	COG1045	serine acetyltransferase
DP51_RS26100	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DP51_RS26105	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DP51_RS26110	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DP51_RS26110	COG0517	IMP dehydrogenase activity
DP51_RS26135	COG2885	chlorophyll binding
DP51_RS26160	COG0824	Thioesterase
DP51_RS26165	COG4221	oxidoreductase activity
DP51_RS26220	COG0450	alkyl hydroperoxide reductase
DP51_RS26225	COG1960	acyl-CoA dehydrogenase activity
DP51_RS26250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DP51_RS26260	COG2814	Major facilitator Superfamily
DP51_RS26280	COG2814	Major facilitator Superfamily
DP51_RS26285	COG0778	Nitroreductase
DP51_RS26290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DP51_RS26295	COG0583	DNA-binding transcription factor activity
DP51_RS26300	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DP51_RS26325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DP51_RS26340	COG4774	siderophore transport
DP51_RS26345	COG1120	ATPase activity
DP51_RS26355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DP51_RS26395	COG0730	response to heat
DP51_RS26405	COG0584	glycerophosphoryl diester phosphodiesterase
DP51_RS26410	COG1280	lysine exporter protein (LysE YggA)
DP51_RS26465	COG0604	alcohol dehydrogenase
DP51_RS26470	COG1733	regulation of RNA biosynthetic process
DP51_RS26480	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DP51_RS26500	COG1773	rubredoxin
DP51_RS26520	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DP51_RS26595	COG1215	transferase activity, transferring glycosyl groups
DP51_RS26610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DP51_RS26625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DP51_RS26650	COG0859	PFAM glycosyl transferase family 9
DP51_RS26705	COG1129	ABC transporter
DP51_RS26715	COG0559	Belongs to the binding-protein-dependent transport system permease family
DP51_RS26725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DP51_RS26735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DP51_RS26745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DP51_RS26765	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DP51_RS26785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DP51_RS26790	COG2226	methyltransferase
DP51_RS26810	COG0762	integral membrane protein
DP51_RS26835	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DP51_RS26845	COG0436	Aminotransferase
DP51_RS26870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DP51_RS26870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DP51_RS26890	COG2814	Major facilitator Superfamily
DP51_RS26905	COG1126	abc transporter atp-binding protein
DP51_RS26910	COG0765	amino acid transport
DP51_RS26915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP51_RS26920	COG0837	glucose binding
DP51_RS26920	COG1737	Transcriptional regulator
DP51_RS26925	COG0363	glucosamine-6-phosphate deaminase activity
DP51_RS26930	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DP51_RS26940	COG1175	transmembrane transport
DP51_RS26945	COG0395	ABC-type sugar transport system, permease component
DP51_RS26950	COG3842	ATPase activity
DP51_RS26955	COG2860	membrane
DP51_RS26960	COG1193	negative regulation of DNA recombination
DP51_RS26965	COG0492	ferredoxin-NADP+ reductase activity
DP51_RS26970	COG1674	ftsk spoiiie
DP51_RS26975	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DP51_RS26985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DP51_RS27025	COG2894	cell division
DP51_RS27050	COG0859	PFAM glycosyl transferase family 9
DP51_RS27060	COG0477	Major facilitator Superfamily
DP51_RS27095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DP51_RS27100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DP51_RS27110	COG1561	YicC-like family, N-terminal region
DP51_RS27125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DP51_RS27145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP51_RS27155	COG1278	Cold shock
DP51_RS27160	COG2176	DNA-directed DNA polymerase activity
DP51_RS27180	COG4772	TonB-dependent receptor
DP51_RS27230	COG0583	DNA-binding transcription factor activity
DP51_RS27240	COG0308	aminopeptidase N
DP51_RS27250	COG2119	membrane
DP51_RS27260	COG0402	S-adenosylhomocysteine deaminase activity
DP51_RS27265	COG2252	PERMEase
DP51_RS27270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DP51_RS27290	COG0154	amidase activity
DP51_RS27295	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DP51_RS27320	COG3383	formate dehydrogenase (NAD+) activity
DP51_RS27335	COG1910	domain protein
DP51_RS27345	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DP51_RS27350	COG0546	phosphoglycolate phosphatase activity
DP51_RS27375	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DP51_RS27380	COG0077	Prephenate dehydratase
DP51_RS27380	COG1605	Chorismate mutase
DP51_RS27385	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DP51_RS27410	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DP51_RS27420	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DP51_RS27445	COG2951	lytic endotransglycosylase activity
DP51_RS27450	COG0123	including yeast histone deacetylase and acetoin utilization protein
DP51_RS27455	COG2267	carboxylic ester hydrolase activity
DP51_RS27465	COG2011	ABC-type metal ion transport system permease component
DP51_RS27485	COG1960	acyl-CoA dehydrogenase activity
DP51_RS27545	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DP51_RS27560	COG0501	Belongs to the peptidase M48B family
DP51_RS27570	COG0521	Mo-molybdopterin cofactor biosynthetic process
DP51_RS27575	COG3028	Belongs to the UPF0307 family
DP51_RS27580	COG0312	modulator of DNA gyrase
DP51_RS27590	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DP51_RS27595	COG2204	response regulator
DP51_RS27615	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DP51_RS27625	COG0640	Transcriptional regulator
DP51_RS27640	COG0114	fumarate hydratase activity
DP51_RS27650	COG0534	Mate efflux family protein
DP51_RS27655	COG2501	S4 domain
DP51_RS27680	COG3045	CreA protein
DP51_RS27695	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DP51_RS27700	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DP51_RS27720	COG1322	Protein conserved in bacteria
DP51_RS27735	COG0303	'Molybdopterin
DP51_RS27745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DP51_RS27750	COG1530	ribonuclease E activity
DP51_RS27760	COG0546	phosphoglycolate phosphatase activity
DP51_RS27785	COG1399	metal-binding, possibly nucleic acid-binding protein
DP51_RS27820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DP51_RS27840	COG3026	antisigma factor binding
DP51_RS27845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP51_RS27860	COG0681	Belongs to the peptidase S26 family
DP51_RS27865	COG0571	ribonuclease III activity
DP51_RS27870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DP51_RS27895	COG2204	response regulator
DP51_RS27910	COG0322	excinuclease ABC activity
DP51_RS27915	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DP51_RS27935	COG1956	GAF domain-containing protein
DP51_RS27940	COG0583	DNA-binding transcription factor activity
DP51_RS27950	COG2153	protein acetylation
DP51_RS27965	COG1999	signal sequence binding
DP51_RS27975	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DP51_RS27980	COG1132	(ABC) transporter
DP51_RS27985	COG0438	transferase activity, transferring glycosyl groups
DP51_RS28000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DP51_RS28005	COG0683	leucine binding
DP51_RS28010	COG3511	phospholipase C
DP51_RS28020	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DP51_RS28025	COG0596	Alpha beta hydrolase
DP51_RS28030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DP51_RS28045	COG3394	polysaccharide catabolic process
DP51_RS28070	COG4598	ABC transporter
DP51_RS28080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DP51_RS28115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP51_RS28125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DP51_RS28155	COG1959	2 iron, 2 sulfur cluster binding
DP51_RS28165	COG2151	metal-sulfur cluster biosynthetic enzyme
DP51_RS28170	COG0822	iron-sulfur transferase activity
DP51_RS28175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DP51_RS28185	COG0396	ATPase activity
DP51_RS28190	COG0719	Fe-S assembly protein
DP51_RS28200	COG0840	transmembrane signaling receptor activity
DP51_RS28205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DP51_RS28210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DP51_RS28225	COG0826	peptidase U32
DP51_RS28230	COG0826	peptidase U32
DP51_RS28235	COG3154	lipid carrier protein
DP51_RS28270	COG2151	metal-sulfur cluster biosynthetic enzyme
DP51_RS28285	COG0415	Belongs to the DNA photolyase family
DP51_RS28290	COG0529	Catalyzes the synthesis of activated sulfate
DP51_RS28320	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DP51_RS28335	COG0402	S-adenosylhomocysteine deaminase activity
DP51_RS28360	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DP51_RS28365	COG0174	glutamine synthetase
DP51_RS28380	COG3668	Plasmid stabilization system
DP51_RS28395	COG0583	DNA-binding transcription factor activity
DP51_RS28400	COG1960	acyl-CoA dehydrogenase activity
DP51_RS28410	COG0477	Major facilitator Superfamily
DP51_RS28420	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DP51_RS28420	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DP51_RS28425	COG1643	Atp-dependent helicase
DP51_RS28445	COG1546	Belongs to the CinA family
DP51_RS28445	COG1058	Belongs to the CinA family
DP51_RS28455	COG0174	glutamine synthetase
DP51_RS28475	COG2197	response regulator
DP51_RS28480	COG4585	Histidine kinase
DP51_RS28485	COG2181	nitrate reductase activity
DP51_RS28490	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DP51_RS28495	COG1140	nitrate reductase beta subunit
DP51_RS28500	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DP51_RS28505	COG2223	nitrite transmembrane transporter activity
DP51_RS28520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DP51_RS28525	COG0339	signal peptide processing
DP51_RS28535	COG4566	intracellular signal transduction
DP51_RS28545	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DP51_RS28550	COG0508	dehydrogenase complex catalyzes the overall conversion of
DP51_RS28555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DP51_RS28570	COG1414	Transcriptional regulator
DP51_RS28590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DP51_RS28600	COG1104	cysteine desulfurase activity
DP51_RS28605	COG0822	iron-sulfur transferase activity
DP51_RS28610	COG0316	Belongs to the HesB IscA family
DP51_RS28630	COG2975	iron-sulfur cluster assembly
DP51_RS28650	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DP51_RS28665	COG1136	(ABC) transporter
DP51_RS28670	COG0084	hydrolase, TatD family'
DP51_RS28675	COG2333	competence protein COMEC
DP51_RS28675	COG0658	competence protein
DP51_RS28680	COG2267	carboxylic ester hydrolase activity
DP51_RS28700	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DP51_RS28710	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DP51_RS28720	COG2833	Protein of unknown function (DUF455)
DP51_RS28725	COG0596	Alpha beta hydrolase
DP51_RS28730	COG0613	PHP domain protein
DP51_RS28735	COG0009	L-threonylcarbamoyladenylate synthase
DP51_RS28740	COG1994	Peptidase M50
DP51_RS28745	COG0180	Tryptophanyl-tRNA synthetase
DP51_RS28755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DP51_RS28760	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DP51_RS28765	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DP51_RS28770	COG2850	peptidyl-arginine hydroxylation
DP51_RS28800	COG0483	inositol monophosphate 1-phosphatase activity
DP51_RS28810	COG1045	serine acetyltransferase
DP51_RS28815	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DP51_RS28825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DP51_RS28850	COG0037	tRNA processing
DP51_RS28855	COG0527	aspartate kinase activity
DP51_RS28895	COG0529	Catalyzes the synthesis of activated sulfate
DP51_RS28895	COG2895	sulfate adenylyltransferase (ATP) activity
DP51_RS28900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DP51_RS28925	COG2175	clavaminate synthase activity
DP51_RS28945	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DP51_RS28950	COG3958	Transketolase
DP51_RS28965	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DP51_RS28985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DP51_RS29000	COG0024	Methionine aminopeptidase
DP51_RS29035	COG0243	molybdopterin cofactor binding
DP51_RS29055	COG4166	transmembrane transport
DP51_RS29060	COG4174	ABC transporter (Permease)
DP51_RS29065	COG4239	(ABC) transporter, permease
DP51_RS29070	COG4172	Belongs to the ABC transporter superfamily
DP51_RS29075	COG0791	NLP P60 protein
DP51_RS29080	COG1752	Esterase of the alpha-beta hydrolase superfamily
DP51_RS29135	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DP51_RS29145	COG0583	DNA-binding transcription factor activity
DP51_RS29155	COG2224	Isocitrate lyase
DP51_RS29160	COG0513	Belongs to the DEAD box helicase family
DP51_RS29170	COG1214	PFAM Peptidase M22, glycoprotease
DP51_RS29180	COG1573	uracil-dna glycosylase
DP51_RS29195	COG0351	phosphomethylpyrimidine kinase
DP51_RS29200	COG0477	Major facilitator Superfamily
DP51_RS29220	COG0488	(ABC) transporter
DP51_RS29225	COG0386	Belongs to the glutathione peroxidase family
DP51_RS29240	COG2890	protein-(glutamine-N5) methyltransferase activity
DP51_RS29250	COG1393	Belongs to the ArsC family
DP51_RS29290	COG0242	peptide deformylase activity
DP51_RS29295	COG1187	pseudouridine synthase activity
DP51_RS29305	COG0024	Methionine aminopeptidase
DP51_RS29335	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DP51_RS29350	COG0750	zinc metalloprotease
DP51_RS29390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DP51_RS29425	COG0330	HflC and HflK could
DP51_RS29435	COG2867	negative regulation of translational initiation
DP51_RS29445	COG0697	spore germination
DP51_RS29505	COG1196	nuclear chromosome segregation
DP51_RS29515	COG2814	Major facilitator Superfamily
DP51_RS29535	COG1619	proteins homologs of microcin C7 resistance protein MccF
DP51_RS29545	COG1953	Uracil, thiamine, allantoin
DP51_RS29560	COG3648	Uricase
DP51_RS29560	COG3195	allantoin biosynthetic process
DP51_RS29565	COG4266	Belongs to the allantoicase family
DP51_RS29580	COG2351	hydroxyisourate hydrolase activity
DP51_RS29590	COG0583	DNA-binding transcription factor activity
DP51_RS29595	COG3360	Dodecin
DP51_RS29620	COG2801	Transposase and inactivated derivatives
DP51_RS29665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DP51_RS29680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DP51_RS29805	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DP51_RS29810	COG1846	Transcriptional regulator
DP51_RS29815	COG1929	Belongs to the glycerate kinase type-1 family
DP51_RS29835	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DP51_RS29890	COG4181	ATPase activity
DP51_RS29905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DP51_RS29915	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DP51_RS29915	COG0047	phosphoribosylformylglycinamidine synthase activity
DP51_RS29925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DP51_RS29950	COG0318	PFAM AMP-dependent synthetase and ligase
DP51_RS29955	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP51_RS29955	COG1024	Enoyl-CoA hydratase
DP51_RS29960	COG1335	isochorismatase
DP51_RS29965	COG0183	Belongs to the thiolase family
DP51_RS29990	COG2130	NADP-dependent
DP51_RS29995	COG0657	acetylesterase activity
DP51_RS30010	COG0354	folic acid binding
DP51_RS30015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DP51_RS30030	COG1247	-acetyltransferase
DP51_RS30035	COG0084	hydrolase, TatD family'
DP51_RS30060	COG0438	transferase activity, transferring glycosyl groups
DP51_RS30080	COG0252	asparaginase activity
DP51_RS30090	COG1652	LysM domain
DP51_RS30100	COG2084	Dehydrogenase
DP51_RS30105	COG3622	Belongs to the hyi family
DP51_RS30110	COG3960	tartronate-semialdehyde synthase activity
DP51_RS30115	COG0583	DNA-binding transcription factor activity
DP51_RS30130	COG1595	DNA-templated transcription, initiation
DP51_RS30170	COG0306	phosphate transporter
DP51_RS30175	COG0791	NLP P60 protein
DP51_RS30180	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DP51_RS30185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DP51_RS30190	COG0726	polysaccharide deacetylase
DP51_RS30195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DP51_RS30195	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DP51_RS30205	COG0463	Glycosyl transferase, family 2
DP51_RS30210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DP51_RS30215	COG2076	Multidrug Resistance protein
DP51_RS30220	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DP51_RS30230	COG0436	Aminotransferase
DP51_RS30250	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DP51_RS30255	COG0314	molybdopterin synthase activity
DP51_RS30260	COG2346	COG2346, Truncated hemoglobins
DP51_RS30265	COG1959	2 iron, 2 sulfur cluster binding
DP51_RS30270	COG0542	response to heat