locus-tag	class	description
BGI46_RS00005	COG2205	protein histidine kinase activity
BGI46_RS00005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BGI46_RS00055	COG0583	DNA-binding transcription factor activity
BGI46_RS00065	COG2814	Major facilitator Superfamily
BGI46_RS00130	COG3328	transposase activity
BGI46_RS00285	COG0457	Tetratricopeptide repeat
BGI46_RS00285	COG0859	PFAM glycosyl transferase family 9
BGI46_RS00330	COG0745	RESPONSE REGULATOR receiver
BGI46_RS00335	COG0583	DNA-binding transcription factor activity
BGI46_RS00390	COG0366	Alpha amylase catalytic
BGI46_RS00395	COG0366	Alpha amylase catalytic
BGI46_RS00445	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BGI46_RS00485	COG0582	viral genome integration into host DNA
BGI46_RS00510	COG4942	peptidase
BGI46_RS00515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BGI46_RS00530	COG0534	Mate efflux family protein
BGI46_RS00610	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BGI46_RS00625	COG0745	RESPONSE REGULATOR receiver
BGI46_RS00640	COG0581	inorganic phosphate transmembrane transporter activity
BGI46_RS00645	COG0573	inorganic phosphate transmembrane transporter activity
BGI46_RS00650	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BGI46_RS00665	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BGI46_RS00670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BGI46_RS00680	COG1534	Rna-binding protein
BGI46_RS00690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BGI46_RS00695	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BGI46_RS00705	COG0505	Belongs to the CarA family
BGI46_RS00735	COG0741	lytic transglycosylase activity
BGI46_RS00735	COG1388	LysM domain
BGI46_RS00740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BGI46_RS00745	COG2226	methyltransferase
BGI46_RS00750	COG0328	RNA-DNA hybrid ribonuclease activity
BGI46_RS00755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BGI46_RS00770	COG0477	Major facilitator Superfamily
BGI46_RS00800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BGI46_RS00810	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BGI46_RS00830	COG3052	prosthetic group binding
BGI46_RS00855	COG0583	DNA-binding transcription factor activity
BGI46_RS00865	COG1250	3-hydroxyacyl-CoA dehydrogenase
BGI46_RS00870	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BGI46_RS00915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BGI46_RS00950	COG0583	DNA-binding transcription factor activity
BGI46_RS00980	COG1522	sequence-specific DNA binding
BGI46_RS00985	COG2188	Transcriptional regulator
BGI46_RS01050	COG1609	Transcriptional regulator
BGI46_RS01055	COG1840	ABC-type Fe3 transport system, periplasmic component
BGI46_RS01060	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BGI46_RS01075	COG1177	transmembrane transport
BGI46_RS01085	COG3842	ATPase activity
BGI46_RS01095	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BGI46_RS01120	COG2814	Major facilitator Superfamily
BGI46_RS01130	COG0697	spore germination
BGI46_RS01145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BGI46_RS01150	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BGI46_RS01195	COG2200	EAL domain
BGI46_RS01205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BGI46_RS01210	COG1074	ATP-dependent DNA helicase activity
BGI46_RS01215	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BGI46_RS01225	COG1289	transmembrane transporter activity
BGI46_RS01250	COG1840	ABC-type Fe3 transport system, periplasmic component
BGI46_RS01255	COG1176	ABC-type spermidine putrescine transport system, permease component I
BGI46_RS01260	COG3842	ATPase activity
BGI46_RS01270	COG1522	sequence-specific DNA binding
BGI46_RS01290	COG1959	2 iron, 2 sulfur cluster binding
BGI46_RS01325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BGI46_RS01330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BGI46_RS01370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BGI46_RS01385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BGI46_RS01385	COG2010	Cytochrome c
BGI46_RS01390	COG2863	cytochrome
BGI46_RS01425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BGI46_RS01445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BGI46_RS01460	COG0006	proline dipeptidase activity
BGI46_RS01535	COG2866	Carboxypeptidase
BGI46_RS01550	COG0436	Aminotransferase
BGI46_RS01560	COG1024	Enoyl-CoA hydratase
BGI46_RS01565	COG0588	phosphoglycerate mutase activity
BGI46_RS01575	COG1960	acyl-CoA dehydrogenase activity
BGI46_RS01595	COG1012	belongs to the aldehyde dehydrogenase family
BGI46_RS01595	COG2030	dehydratase
BGI46_RS01600	COG1960	acyl-CoA dehydrogenase activity
BGI46_RS01605	COG1960	acyl-CoA dehydrogenase activity
BGI46_RS01625	COG1007	ATP synthesis coupled electron transport
BGI46_RS01660	COG1034	ATP synthesis coupled electron transport
BGI46_RS01670	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BGI46_RS01705	COG0149	triose-phosphate isomerase activity
BGI46_RS01710	COG0604	alcohol dehydrogenase
BGI46_RS01710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BGI46_RS01710	COG3321	synthase
BGI46_RS01710	COG4221	oxidoreductase activity
BGI46_RS01730	COG0683	leucine binding
BGI46_RS01745	COG0288	reversible hydration of carbon dioxide
BGI46_RS01750	COG0659	secondary active sulfate transmembrane transporter activity
BGI46_RS01765	COG1183	phosphatidylcholine synthase activity
BGI46_RS01785	COG0028	Belongs to the TPP enzyme family
BGI46_RS01820	COG0438	transferase activity, transferring glycosyl groups
BGI46_RS01840	COG1028	Short-chain dehydrogenase reductase Sdr
BGI46_RS01850	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BGI46_RS01860	COG0154	amidase activity
BGI46_RS01870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BGI46_RS01900	COG0745	RESPONSE REGULATOR receiver
BGI46_RS01905	COG2205	protein histidine kinase activity
BGI46_RS01920	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BGI46_RS01925	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BGI46_RS01955	COG1028	Short-chain dehydrogenase reductase Sdr
BGI46_RS01975	COG0151	Belongs to the GarS family
BGI46_RS01990	COG0799	negative regulation of ribosome biogenesis
BGI46_RS02125	COG2233	PERMEase
BGI46_RS02175	COG1595	DNA-templated transcription, initiation
BGI46_RS02185	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BGI46_RS02225	COG0859	PFAM glycosyl transferase family 9
BGI46_RS02230	COG0438	transferase activity, transferring glycosyl groups
BGI46_RS02270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BGI46_RS02280	COG0513	Belongs to the DEAD box helicase family
BGI46_RS02315	COG1674	ftsk spoiiie
BGI46_RS02320	COG2706	6-phosphogluconolactonase activity
BGI46_RS02330	COG3387	PFAM Glycoside hydrolase 15-related
BGI46_RS02340	COG1309	transcriptional regulator
BGI46_RS02345	COG2878	Part of a membrane complex involved in electron transport
BGI46_RS02350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BGI46_RS02385	COG3135	benzoate transporter
BGI46_RS02400	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BGI46_RS02415	COG4106	trans-aconitate 2-methyltransferase activity
BGI46_RS02440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BGI46_RS02450	COG0697	spore germination
BGI46_RS02455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BGI46_RS02500	COG0477	Major facilitator Superfamily
BGI46_RS02510	COG0583	DNA-binding transcription factor activity
BGI46_RS02520	COG0583	DNA-binding transcription factor activity
BGI46_RS02550	COG0488	(ABC) transporter
BGI46_RS02560	COG1773	rubredoxin
BGI46_RS02725	COG1881	PFAM PEBP family protein
BGI46_RS02730	COG2814	Major facilitator Superfamily
BGI46_RS02750	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BGI46_RS02780	COG1116	anion transmembrane transporter activity
BGI46_RS02785	COG1176	ABC-type spermidine putrescine transport system, permease component I
BGI46_RS02820	COG1741	Belongs to the pirin family
BGI46_RS02835	COG4215	(ABC) transporter
BGI46_RS02855	COG0347	Belongs to the P(II) protein family
BGI46_RS02875	COG1472	Belongs to the glycosyl hydrolase 3 family
BGI46_RS02880	COG2827	Endonuclease containing a URI domain
BGI46_RS02885	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BGI46_RS02900	COG2271	Major facilitator Superfamily
BGI46_RS02945	COG2226	methyltransferase
BGI46_RS02985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BGI46_RS03010	COG0489	protein tyrosine kinase activity
BGI46_RS03020	COG3047	cAMP biosynthetic process
BGI46_RS03020	COG2885	chlorophyll binding
BGI46_RS03050	COG2911	Protein conserved in bacteria
BGI46_RS03055	COG0729	surface antigen
BGI46_RS03065	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BGI46_RS03085	COG0489	protein tyrosine kinase activity
BGI46_RS03090	COG2259	Doxx family
BGI46_RS03095	COG1492	cobalamin metabolic process
BGI46_RS03105	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BGI46_RS03115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BGI46_RS03135	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BGI46_RS03140	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BGI46_RS03145	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BGI46_RS03155	COG4206	TonB-dependent receptor
BGI46_RS03190	COG0583	DNA-binding transcription factor activity
BGI46_RS03205	COG4654	Cytochrome c, class I
BGI46_RS03225	COG0795	lipopolysaccharide-transporting ATPase activity
BGI46_RS03245	COG1648	precorrin-2 dehydrogenase activity
BGI46_RS03245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BGI46_RS03250	COG2895	sulfate adenylyltransferase (ATP) activity
BGI46_RS03260	COG0175	sulfate reduction
BGI46_RS03275	COG0583	DNA-binding transcription factor activity
BGI46_RS03295	COG1396	sequence-specific DNA binding
BGI46_RS03305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BGI46_RS03310	COG2258	MOSC domain
BGI46_RS03315	COG2267	carboxylic ester hydrolase activity
BGI46_RS03325	COG0583	DNA-binding transcription factor activity
BGI46_RS03335	COG1187	pseudouridine synthase activity
BGI46_RS03350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BGI46_RS03350	COG0543	2 iron, 2 sulfur cluster binding
BGI46_RS03355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BGI46_RS03360	COG0456	acetyltransferase
BGI46_RS03400	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BGI46_RS03405	COG1047	Peptidyl-prolyl cis-trans
BGI46_RS03425	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BGI46_RS03450	COG1511	domain protein
BGI46_RS03450	COG3264	Mechanosensitive ion channel
BGI46_RS03455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BGI46_RS03455	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BGI46_RS03460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BGI46_RS03465	COG0196	riboflavin kinase activity
BGI46_RS03470	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BGI46_RS03500	COG1113	amino acid transport
BGI46_RS03505	COG0542	response to heat
BGI46_RS03515	COG1278	Cold shock
BGI46_RS03555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BGI46_RS03590	COG0656	L-ascorbic acid biosynthetic process
BGI46_RS03595	COG2188	Transcriptional regulator
BGI46_RS03615	COG2814	Major facilitator Superfamily
BGI46_RS03675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BGI46_RS03680	COG1570	exodeoxyribonuclease VII activity
BGI46_RS03690	COG1663	tetraacyldisaccharide 4'-kinase activity
BGI46_RS03730	COG0728	peptidoglycan biosynthetic process
BGI46_RS03750	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BGI46_RS03755	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BGI46_RS03770	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BGI46_RS03775	COG0318	PFAM AMP-dependent synthetase and ligase
BGI46_RS03780	COG4974	Belongs to the 'phage' integrase family
BGI46_RS03790	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BGI46_RS03795	COG0802	atpase or kinase
BGI46_RS03800	COG0860	N-Acetylmuramoyl-L-alanine amidase
BGI46_RS03815	COG1741	Belongs to the pirin family
BGI46_RS03820	COG3118	belongs to the thioredoxin family
BGI46_RS03830	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BGI46_RS03840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BGI46_RS03855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BGI46_RS03865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BGI46_RS03870	COG1522	sequence-specific DNA binding
BGI46_RS03900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BGI46_RS03905	COG1012	belongs to the aldehyde dehydrogenase family
BGI46_RS03915	COG0583	DNA-binding transcription factor activity
BGI46_RS03920	COG0246	Mannitol dehydrogenase
BGI46_RS03925	COG1070	Carbohydrate kinase
BGI46_RS03930	COG2390	Transcriptional regulator
BGI46_RS03945	COG0583	DNA-binding transcription factor activity
BGI46_RS03960	COG3842	ATPase activity
BGI46_RS03965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BGI46_RS03975	COG1175	transmembrane transport
BGI46_RS03990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BGI46_RS04000	COG0735	belongs to the Fur family
BGI46_RS04010	COG1121	(ABC) transporter
BGI46_RS04015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BGI46_RS04020	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BGI46_RS04035	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BGI46_RS04040	COG2233	PERMEase
BGI46_RS04055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BGI46_RS04060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BGI46_RS04090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BGI46_RS04135	COG0009	L-threonylcarbamoyladenylate synthase
BGI46_RS04140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BGI46_RS04145	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BGI46_RS04150	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BGI46_RS04160	COG0469	pyruvate kinase activity
BGI46_RS04170	COG0126	phosphoglycerate kinase activity
BGI46_RS04195	COG0859	PFAM glycosyl transferase family 9
BGI46_RS04205	COG0429	hydrolase of the alpha beta-hydrolase fold
BGI46_RS04215	COG4783	chaperone-mediated protein folding
BGI46_RS04245	COG3307	-O-antigen
BGI46_RS04250	COG4969	Belongs to the N-Me-Phe pilin family
BGI46_RS04255	COG0861	Integral membrane protein TerC family
BGI46_RS04260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BGI46_RS04275	COG2137	regulation of response to DNA damage stimulus
BGI46_RS04280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BGI46_RS04315	COG2801	Transposase and inactivated derivatives
BGI46_RS04380	COG5002	protein histidine kinase activity
BGI46_RS04380	COG0784	Response regulator, receiver
BGI46_RS04385	COG0583	DNA-binding transcription factor activity
BGI46_RS04425	COG0028	Belongs to the TPP enzyme family
BGI46_RS04430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BGI46_RS04435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BGI46_RS04520	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BGI46_RS04525	COG0583	DNA-binding transcription factor activity
BGI46_RS04545	COG0840	transmembrane signaling receptor activity
BGI46_RS04590	COG4948	Mandelate Racemase Muconate Lactonizing
BGI46_RS04620	COG0513	Belongs to the DEAD box helicase family
BGI46_RS04665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BGI46_RS04670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BGI46_RS04685	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BGI46_RS04690	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BGI46_RS04695	COG0367	asparagine synthase
BGI46_RS04710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BGI46_RS04720	COG1396	sequence-specific DNA binding
BGI46_RS04725	COG2814	Major facilitator Superfamily
BGI46_RS04730	COG0583	DNA-binding transcription factor activity
BGI46_RS04745	COG1702	phosphate starvation-inducible protein PhoH
BGI46_RS04760	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BGI46_RS04770	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BGI46_RS04775	COG0752	glycyl-tRNA synthetase alpha subunit
BGI46_RS04780	COG0751	glycine-tRNA ligase activity
BGI46_RS04785	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BGI46_RS04790	COG0204	Acyl-transferase
BGI46_RS04820	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BGI46_RS04835	COG3178	'Phosphotransferase
BGI46_RS04840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BGI46_RS04850	COG5265	(ABC) transporter
BGI46_RS04870	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BGI46_RS04875	COG1024	Enoyl-CoA hydratase
BGI46_RS04880	COG0183	Belongs to the thiolase family
BGI46_RS04885	COG1024	Enoyl-CoA hydratase
BGI46_RS04885	COG1250	3-hydroxyacyl-CoA dehydrogenase
BGI46_RS04890	COG1960	acyl-CoA dehydrogenase activity
BGI46_RS04905	COG0494	nUDIX hydrolase
BGI46_RS04980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BGI46_RS04990	COG0251	oxidation-reduction process
BGI46_RS05000	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BGI46_RS05025	COG0477	Major facilitator Superfamily
BGI46_RS05070	COG1596	polysaccharide export
BGI46_RS05075	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BGI46_RS05095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BGI46_RS05105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BGI46_RS05125	COG2204	response regulator
BGI46_RS05170	COG5001	Diguanylate cyclase
BGI46_RS05170	COG5002	protein histidine kinase activity
BGI46_RS05185	COG0235	Class ii aldolase
BGI46_RS05245	COG0142	geranyltranstransferase activity
BGI46_RS05345	COG0629	single-stranded DNA binding
BGI46_RS05350	COG2814	Major facilitator Superfamily
BGI46_RS05380	COG1280	lysine exporter protein (LysE YggA)
BGI46_RS05405	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BGI46_RS05420	COG1137	ATPase activity
BGI46_RS05425	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BGI46_RS05435	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BGI46_RS05460	COG1194	a g-specific adenine glycosylase
BGI46_RS05475	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BGI46_RS05490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BGI46_RS05510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BGI46_RS05525	COG0742	ribosomal rna small subunit methyltransferase
BGI46_RS05535	COG0625	glutathione transferase activity
BGI46_RS05545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BGI46_RS05555	COG0243	molybdopterin cofactor binding
BGI46_RS05560	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BGI46_RS05575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BGI46_RS05585	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BGI46_RS05595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BGI46_RS05615	COG1294	oxidase, subunit
BGI46_RS05640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BGI46_RS05640	COG1263	PTS System
BGI46_RS05640	COG2190	(PTS) system
BGI46_RS05645	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BGI46_RS05645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BGI46_RS05650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BGI46_RS05655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BGI46_RS05660	COG2188	Transcriptional regulator
BGI46_RS05670	COG0583	DNA-binding transcription factor activity
BGI46_RS05715	COG0318	PFAM AMP-dependent synthetase and ligase
BGI46_RS05725	COG1960	acyl-CoA dehydrogenase activity
BGI46_RS05735	COG2226	methyltransferase
BGI46_RS05770	COG2814	Major facilitator Superfamily
BGI46_RS05780	COG0587	DNA-directed DNA polymerase activity
BGI46_RS05795	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BGI46_RS05830	COG0840	transmembrane signaling receptor activity
BGI46_RS05840	COG1999	signal sequence binding
BGI46_RS05850	COG1612	heme a metabolic process
BGI46_RS05880	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BGI46_RS05890	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BGI46_RS05905	COG2226	methyltransferase
BGI46_RS05910	COG1040	competence protein
BGI46_RS05925	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BGI46_RS05945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BGI46_RS05955	COG0793	Belongs to the peptidase S41A family
BGI46_RS05960	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BGI46_RS05970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BGI46_RS05975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BGI46_RS05985	COG0189	ligase activity
BGI46_RS05995	COG0004	ammonium transporteR
BGI46_RS06005	COG2960	long-chain fatty acid transporting porin activity
BGI46_RS06045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BGI46_RS06055	COG4191	Histidine kinase
BGI46_RS06065	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BGI46_RS06075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BGI46_RS06080	COG1960	acyl-CoA dehydrogenase activity
BGI46_RS06085	COG1960	acyl-CoA dehydrogenase activity
BGI46_RS06090	COG1250	3-hydroxyacyl-CoA dehydrogenase
BGI46_RS06090	COG1024	Enoyl-CoA hydratase
BGI46_RS06095	COG0583	DNA-binding transcription factor activity
BGI46_RS06130	COG0583	DNA-binding transcription factor activity
BGI46_RS06135	COG2921	Belongs to the UPF0250 family
BGI46_RS06145	COG1686	Belongs to the peptidase S11 family
BGI46_RS06180	COG1127	ABC transporter
BGI46_RS06185	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BGI46_RS06190	COG0737	Belongs to the 5'-nucleotidase family
BGI46_RS06205	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BGI46_RS06215	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BGI46_RS06240	COG1024	Enoyl-CoA hydratase
BGI46_RS06295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BGI46_RS06300	COG4221	oxidoreductase activity
BGI46_RS06305	COG1028	Short-chain dehydrogenase reductase Sdr
BGI46_RS06325	COG0747	negative chemotaxis
BGI46_RS06330	COG0488	(ABC) transporter
BGI46_RS06350	COG0288	reversible hydration of carbon dioxide
BGI46_RS06355	COG0183	Belongs to the thiolase family
BGI46_RS06365	COG3012	SEC-C Motif Domain Protein
BGI46_RS06390	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BGI46_RS06420	COG1785	Belongs to the alkaline phosphatase family
BGI46_RS06430	COG2199	diguanylate cyclase activity
BGI46_RS06430	COG2200	EAL domain
BGI46_RS06435	COG0025	NhaP-type Na H and K H
BGI46_RS06480	COG4650	regulator
BGI46_RS06510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BGI46_RS06530	COG1999	signal sequence binding
BGI46_RS06565	COG3511	phospholipase C
BGI46_RS06585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BGI46_RS06615	COG0596	Alpha beta hydrolase
BGI46_RS06630	COG0583	DNA-binding transcription factor activity
BGI46_RS06635	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BGI46_RS06665	COG0840	transmembrane signaling receptor activity
BGI46_RS06670	COG1609	Transcriptional regulator
BGI46_RS06730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BGI46_RS06745	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BGI46_RS06750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BGI46_RS06770	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BGI46_RS06775	COG1704	LemA family
BGI46_RS06900	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BGI46_RS06915	COG2824	Alkylphosphonate utilization operon protein PhnA
BGI46_RS06945	COG0583	DNA-binding transcription factor activity
BGI46_RS06955	COG2233	PERMEase
BGI46_RS06965	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BGI46_RS06975	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BGI46_RS06985	COG1706	bacterial-type flagellum-dependent cell motility
BGI46_RS06990	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BGI46_RS07005	COG1749	Flagellar hook protein flgE
BGI46_RS07010	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BGI46_RS07015	COG1558	bacterial-type flagellum-dependent cell motility
BGI46_RS07020	COG1815	bacterial-type flagellum-dependent cell motility
BGI46_RS07030	COG2747	anti-sigma28 factor FlgM
BGI46_RS07075	COG0741	lytic transglycosylase activity
BGI46_RS07080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BGI46_RS07090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BGI46_RS07095	COG1984	allophanate hydrolase subunit 2
BGI46_RS07125	COG4608	Belongs to the ABC transporter superfamily
BGI46_RS07130	COG0444	Belongs to the ABC transporter superfamily
BGI46_RS07135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BGI46_RS07140	COG0601	transmembrane transport
BGI46_RS07145	COG0747	negative chemotaxis
BGI46_RS07165	COG0579	oxidoreductase
BGI46_RS07185	COG3568	Endonuclease Exonuclease Phosphatase
BGI46_RS07190	COG1280	lysine exporter protein (LysE YggA)
BGI46_RS07210	COG0531	amino acid
BGI46_RS07225	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BGI46_RS07285	COG1960	acyl-CoA dehydrogenase activity
BGI46_RS07300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BGI46_RS07330	COG0667	Aldo Keto reductase
BGI46_RS07365	COG1560	Kdo2-lipid A biosynthetic process
BGI46_RS07380	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BGI46_RS07390	COG0523	cobalamin synthesis protein
BGI46_RS07420	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BGI46_RS07445	COG1309	transcriptional regulator
BGI46_RS07460	COG2814	Major facilitator Superfamily
BGI46_RS07470	COG2207	Transcriptional regulator
BGI46_RS07475	COG1064	alcohol dehydrogenase
BGI46_RS07490	COG0708	Exodeoxyribonuclease III
BGI46_RS07495	COG2326	polyphosphate kinase activity
BGI46_RS07515	COG1077	Cell shape determining protein MreB Mrl
BGI46_RS07530	COG0768	penicillin binding
BGI46_RS07535	COG0772	Belongs to the SEDS family
BGI46_RS07560	COG0720	synthase
BGI46_RS07565	COG0602	queuosine metabolic process
BGI46_RS07585	COG2204	response regulator
BGI46_RS07590	COG5000	phosphorelay sensor kinase activity
BGI46_RS07600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BGI46_RS07600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BGI46_RS07625	COG0242	peptide deformylase activity
BGI46_RS07630	COG0758	DNA mediated transformation
BGI46_RS07645	COG0583	DNA-binding transcription factor activity
BGI46_RS07650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BGI46_RS07690	COG4695	Portal protein
BGI46_RS07700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BGI46_RS07715	COG0583	DNA-binding transcription factor activity
BGI46_RS07745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BGI46_RS07760	COG2169	Transcriptional regulator
BGI46_RS07760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BGI46_RS07790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BGI46_RS07845	COG0582	viral genome integration into host DNA
BGI46_RS07885	COG0592	DNA-directed DNA polymerase activity
BGI46_RS07910	COG0753	catalase activity
BGI46_RS07955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BGI46_RS07960	COG1024	Enoyl-CoA hydratase
BGI46_RS07960	COG1250	3-hydroxyacyl-CoA dehydrogenase
BGI46_RS07965	COG0183	Belongs to the thiolase family
BGI46_RS07970	COG1960	acyl-CoA dehydrogenase activity
BGI46_RS08005	COG1695	Transcriptional regulator
BGI46_RS08080	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BGI46_RS08105	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BGI46_RS08120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BGI46_RS08130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BGI46_RS08150	COG0789	Transcriptional regulator
BGI46_RS08160	COG1987	bacterial-type flagellum assembly
BGI46_RS08175	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BGI46_RS08195	COG1346	cytolysis
BGI46_RS08205	COG0583	DNA-binding transcription factor activity
BGI46_RS08210	COG2814	Major facilitator Superfamily
BGI46_RS08215	COG1846	Transcriptional regulator
BGI46_RS08260	COG2165	general secretion pathway protein
BGI46_RS08280	COG1459	type II secretion system
BGI46_RS08305	COG0523	cobalamin synthesis protein
BGI46_RS08350	COG0519	Catalyzes the synthesis of GMP from XMP
BGI46_RS08350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BGI46_RS08355	COG1902	pentaerythritol trinitrate reductase activity
BGI46_RS08375	COG0642	Histidine kinase
BGI46_RS08395	COG3186	Phenylalanine-4-hydroxylase
BGI46_RS08400	COG1522	sequence-specific DNA binding
BGI46_RS08415	COG0583	DNA-binding transcription factor activity
BGI46_RS08425	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BGI46_RS08455	COG0559	Belongs to the binding-protein-dependent transport system permease family
BGI46_RS08500	COG1192	Involved in chromosome partitioning
BGI46_RS08505	COG1475	DNA binding
BGI46_RS08510	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BGI46_RS08520	COG0356	it plays a direct role in the translocation of protons across the membrane
BGI46_RS08565	COG0318	PFAM AMP-dependent synthetase and ligase
BGI46_RS08580	COG1832	CoA-binding protein
BGI46_RS08600	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BGI46_RS08620	COG0506	proline dehydrogenase activity
BGI46_RS08620	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BGI46_RS08620	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BGI46_RS08635	COG1960	acyl-CoA dehydrogenase activity
BGI46_RS08655	COG0436	Aminotransferase
BGI46_RS08675	COG0277	FAD linked oxidase domain protein
BGI46_RS08685	COG0789	Transcriptional regulator
BGI46_RS08705	COG0668	transmembrane transport
BGI46_RS08725	COG0531	amino acid
BGI46_RS08730	COG4303	Ethanolamine ammonia lyase large subunit
BGI46_RS08735	COG4302	ethanolamine ammonia-lyase activity
BGI46_RS08745	COG1012	belongs to the aldehyde dehydrogenase family
BGI46_RS08770	COG1760	l-serine dehydratase
BGI46_RS08790	COG0509	glycine decarboxylation via glycine cleavage system
BGI46_RS08805	COG0673	inositol 2-dehydrogenase activity
BGI46_RS08825	COG0210	DNA helicase
BGI46_RS08830	COG3245	cytochrome
BGI46_RS08850	COG0582	viral genome integration into host DNA
BGI46_RS08895	COG3397	chitin binding
BGI46_RS08920	COG2267	carboxylic ester hydrolase activity
BGI46_RS08995	COG1028	Short-chain dehydrogenase reductase Sdr
BGI46_RS09010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BGI46_RS09055	COG0519	Catalyzes the synthesis of GMP from XMP
BGI46_RS09065	COG0561	phosphatase activity
BGI46_RS09070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BGI46_RS09085	COG0438	transferase activity, transferring glycosyl groups
BGI46_RS09110	COG1360	Flagellar Motor Protein
BGI46_RS09115	COG2201	protein-glutamate methylesterase activity
BGI46_RS09135	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BGI46_RS09145	COG2201	protein-glutamate methylesterase activity
BGI46_RS09155	COG0745	RESPONSE REGULATOR receiver
BGI46_RS09160	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BGI46_RS09180	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BGI46_RS09185	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BGI46_RS09210	COG1950	PFAM Membrane protein of
BGI46_RS09215	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BGI46_RS09235	COG2070	2-Nitropropane dioxygenase
BGI46_RS09270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BGI46_RS09275	COG1522	sequence-specific DNA binding
BGI46_RS09285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BGI46_RS09310	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BGI46_RS09315	COG2823	Periplasmic or secreted lipoprotein
BGI46_RS09340	COG2801	Transposase and inactivated derivatives
BGI46_RS09345	COG2963	transposase activity
BGI46_RS09370	COG3311	Transcriptional regulator
BGI46_RS09380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BGI46_RS09410	COG1002	Type II restriction enzyme, methylase subunits
BGI46_RS09415	COG1061	Type III restriction enzyme res subunit
BGI46_RS09420	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BGI46_RS09435	COG1113	amino acid transport
BGI46_RS09485	COG2084	Dehydrogenase
BGI46_RS09490	COG1280	lysine exporter protein (LysE YggA)
BGI46_RS09495	COG2814	Major facilitator Superfamily
BGI46_RS09500	COG0583	DNA-binding transcription factor activity
BGI46_RS09505	COG3047	cAMP biosynthetic process
BGI46_RS09525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BGI46_RS09540	COG1881	PFAM PEBP family protein
BGI46_RS09545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BGI46_RS09555	COG0280	phosphate acetyltransferase
BGI46_RS09555	COG0281	malic enzyme
BGI46_RS09585	COG1522	sequence-specific DNA binding
BGI46_RS09605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BGI46_RS09610	COG2151	metal-sulfur cluster biosynthetic enzyme
BGI46_RS09615	COG3396	Phenylacetate-CoA oxygenase
BGI46_RS09620	COG3460	Phenylacetate-CoA oxygenase
BGI46_RS09625	COG3396	Phenylacetate-CoA oxygenase
BGI46_RS09705	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BGI46_RS09755	COG0514	ATP-dependent DNA helicase (RecQ)
BGI46_RS09885	COG0201	protein transport
BGI46_RS09930	COG4232	protein-disulfide reductase activity
BGI46_RS09950	COG1333	cytochrome c biogenesis protein
BGI46_RS09955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BGI46_RS09960	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BGI46_RS09965	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BGI46_RS10025	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BGI46_RS10035	COG1175	transmembrane transport
BGI46_RS10040	COG0395	ABC-type sugar transport system, permease component
BGI46_RS10045	COG3842	ATPase activity
BGI46_RS10050	COG0584	glycerophosphoryl diester phosphodiesterase
BGI46_RS10065	COG0070	glutamate synthase
BGI46_RS10065	COG0069	glutamate synthase activity
BGI46_RS10065	COG0067	glutamate synthase
BGI46_RS10080	COG1115	amino acid carrier protein
BGI46_RS10095	COG4178	(ABC) transporter
BGI46_RS10120	COG1127	ABC transporter
BGI46_RS10125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BGI46_RS10130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BGI46_RS10155	COG1131	(ABC) transporter
BGI46_RS10160	COG0842	Transport permease protein
BGI46_RS10185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BGI46_RS10195	COG2095	MarC family integral membrane protein
BGI46_RS10245	COG0805	protein transport
BGI46_RS10255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BGI46_RS10260	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BGI46_RS10265	COG0723	plastoquinol--plastocyanin reductase activity
BGI46_RS10270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BGI46_RS10275	COG2857	Cytochrome c1
BGI46_RS10280	COG0625	glutathione transferase activity
BGI46_RS10285	COG2969	positive regulation of protein catabolic process
BGI46_RS10560	COG0308	aminopeptidase N
BGI46_RS10640	COG0443	Heat shock 70 kDa protein
BGI46_RS10650	COG1278	Cold shock
BGI46_RS10655	COG0531	amino acid
BGI46_RS10660	COG3384	dioxygenase
BGI46_RS10670	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BGI46_RS10675	COG2890	protein-(glutamine-N5) methyltransferase activity
BGI46_RS10705	COG0006	proline dipeptidase activity
BGI46_RS10710	COG1335	isochorismatase
BGI46_RS10720	COG0488	(ABC) transporter
BGI46_RS10735	COG0584	glycerophosphoryl diester phosphodiesterase
BGI46_RS10775	COG0012	GTP binding
BGI46_RS10805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BGI46_RS10810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BGI46_RS10825	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BGI46_RS10845	COG0512	Glutamine amidotransferase of anthranilate synthase
BGI46_RS10860	COG0546	phosphoglycolate phosphatase activity
BGI46_RS10865	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BGI46_RS10875	COG2967	ApaG domain
BGI46_RS10885	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BGI46_RS10895	COG2050	protein possibly involved in aromatic compounds catabolism
BGI46_RS10900	COG1024	Enoyl-CoA hydratase
BGI46_RS10905	COG0183	Belongs to the thiolase family
BGI46_RS10915	COG1024	Enoyl-CoA hydratase
BGI46_RS10965	COG0243	molybdopterin cofactor binding
BGI46_RS10970	COG0318	PFAM AMP-dependent synthetase and ligase
BGI46_RS10975	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BGI46_RS10995	COG3116	cell division
BGI46_RS11005	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BGI46_RS11010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BGI46_RS11045	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BGI46_RS11065	COG0678	peroxiredoxin activity
BGI46_RS11100	COG0494	nUDIX hydrolase
BGI46_RS11105	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BGI46_RS11120	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BGI46_RS11130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BGI46_RS11135	COG4536	flavin adenine dinucleotide binding
BGI46_RS11225	COG0142	geranyltranstransferase activity
BGI46_RS11275	COG2095	MarC family integral membrane protein
BGI46_RS11280	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BGI46_RS11285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BGI46_RS11340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BGI46_RS11345	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BGI46_RS11360	COG0439	Biotin carboxylase
BGI46_RS11365	COG0511	ligase activity, forming carbon-carbon bonds
BGI46_RS11370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BGI46_RS11375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BGI46_RS11385	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BGI46_RS11390	COG3150	esterase
BGI46_RS11395	COG0557	exoribonuclease II activity
BGI46_RS11400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BGI46_RS11405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BGI46_RS11425	COG1414	Transcriptional regulator
BGI46_RS11430	COG3734	2-keto-3-deoxy-galactonokinase
BGI46_RS11440	COG1028	Short-chain dehydrogenase reductase Sdr
BGI46_RS11455	COG1172	Belongs to the binding-protein-dependent transport system permease family
BGI46_RS11460	COG1028	Short-chain dehydrogenase reductase Sdr
BGI46_RS11470	COG0284	orotidine-5'-phosphate decarboxylase activity
BGI46_RS11475	COG1546	Belongs to the CinA family
BGI46_RS11480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BGI46_RS11510	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BGI46_RS11520	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BGI46_RS11525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BGI46_RS11530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BGI46_RS11540	COG2814	Major facilitator Superfamily
BGI46_RS11555	COG0583	DNA-binding transcription factor activity
BGI46_RS11570	COG1301	dicarboxylic acid transport
BGI46_RS11575	COG4266	Belongs to the allantoicase family
BGI46_RS11580	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BGI46_RS11585	COG0735	belongs to the Fur family
BGI46_RS11590	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BGI46_RS11620	COG1466	dna polymerase III delta subunit
BGI46_RS11625	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BGI46_RS11630	COG1981	membrane
BGI46_RS11645	COG1737	Transcriptional regulator
BGI46_RS11645	COG0837	glucose binding
BGI46_RS11660	COG0800	Aldolase
BGI46_RS11680	COG2223	nitrite transmembrane transporter activity
BGI46_RS11685	COG0583	DNA-binding transcription factor activity
BGI46_RS11695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BGI46_RS11700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BGI46_RS11705	COG0765	amino acid transport
BGI46_RS11710	COG0765	amino acid transport
BGI46_RS11715	COG1126	abc transporter atp-binding protein
BGI46_RS11735	COG0459	protein refolding
BGI46_RS11775	COG0121	glutamine amidotransferase
BGI46_RS11785	COG0418	dihydroorotase activity
BGI46_RS11820	COG4977	sequence-specific DNA binding
BGI46_RS11820	COG1917	Cupin 2, conserved barrel domain protein
BGI46_RS11825	COG0625	glutathione transferase activity
BGI46_RS11830	COG0625	glutathione transferase activity
BGI46_RS11845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BGI46_RS11855	COG0588	phosphoglycerate mutase activity
BGI46_RS11895	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BGI46_RS11900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BGI46_RS11905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BGI46_RS11910	COG0006	proline dipeptidase activity
BGI46_RS11920	COG0625	glutathione transferase activity
BGI46_RS11930	COG0069	glutamate synthase activity
BGI46_RS12010	COG3008	intermembrane lipid transfer
BGI46_RS12010	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BGI46_RS12015	COG2995	paraquat-inducible protein a
BGI46_RS12035	COG2353	YceI-like domain
BGI46_RS12040	COG2353	YceI-like domain
BGI46_RS12055	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BGI46_RS12060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BGI46_RS12065	COG1862	Preprotein translocase
BGI46_RS12070	COG0343	queuine tRNA-ribosyltransferase activity
BGI46_RS12085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BGI46_RS12110	COG0783	Belongs to the Dps family
BGI46_RS12135	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BGI46_RS12140	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BGI46_RS12145	COG2188	Transcriptional regulator
BGI46_RS12155	COG3624	Phosphonate C-P lyase system protein PhnG
BGI46_RS12165	COG3626	phosphonate metabolism
BGI46_RS12170	COG3627	carbon phosphorus lyase activity
BGI46_RS12175	COG4107	phosphonate C-P lyase system protein PhnK
BGI46_RS12180	COG4778	phosphonate C-P lyase system protein PhnL
BGI46_RS12185	COG3454	Phosphonate metabolism
BGI46_RS12195	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BGI46_RS12200	COG3639	organic phosphonate transmembrane transporter activity
BGI46_RS12220	COG0247	lactate metabolic process
BGI46_RS12225	COG0277	FAD linked oxidase domain protein
BGI46_RS12230	COG0277	FAD linked oxidase domain protein
BGI46_RS12235	COG0277	FAD linked oxidase domain protein
BGI46_RS12240	COG2096	Adenosyltransferase
BGI46_RS12245	COG1017	nitric oxide dioxygenase activity
BGI46_RS12245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BGI46_RS12260	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BGI46_RS12270	COG0312	modulator of DNA gyrase
BGI46_RS12275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BGI46_RS12280	COG3164	Protein of unknown function
BGI46_RS12285	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BGI46_RS12290	COG0497	DNA recombination
BGI46_RS12295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BGI46_RS12335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BGI46_RS12345	COG1428	Deoxynucleoside kinase
BGI46_RS12350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BGI46_RS12355	COG0617	tRNA 3'-terminal CCA addition
BGI46_RS12365	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BGI46_RS12395	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BGI46_RS12400	COG0586	Pfam SNARE associated Golgi protein
BGI46_RS12500	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BGI46_RS12515	COG1368	sulfuric ester hydrolase activity
BGI46_RS12520	COG0604	alcohol dehydrogenase
BGI46_RS12520	COG3321	synthase
BGI46_RS12520	COG1028	Short-chain dehydrogenase reductase Sdr
BGI46_RS12525	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BGI46_RS12530	COG0156	8-amino-7-oxononanoate synthase activity
BGI46_RS12580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BGI46_RS12585	COG0489	protein tyrosine kinase activity
BGI46_RS12585	COG3206	protein involved in exopolysaccharide biosynthesis
BGI46_RS12595	COG3562	capsule polysaccharide
BGI46_RS12600	COG1045	serine acetyltransferase
BGI46_RS12615	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BGI46_RS12620	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BGI46_RS12625	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BGI46_RS12625	COG0517	IMP dehydrogenase activity
BGI46_RS12660	COG2885	chlorophyll binding
BGI46_RS12685	COG0824	Thioesterase
BGI46_RS12690	COG4221	oxidoreductase activity
BGI46_RS12750	COG0450	alkyl hydroperoxide reductase
BGI46_RS12760	COG1960	acyl-CoA dehydrogenase activity
BGI46_RS12795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BGI46_RS12805	COG2814	Major facilitator Superfamily
BGI46_RS12835	COG2814	Major facilitator Superfamily
BGI46_RS12840	COG0778	Nitroreductase
BGI46_RS12845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BGI46_RS12850	COG0583	DNA-binding transcription factor activity
BGI46_RS12860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BGI46_RS12895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BGI46_RS12920	COG4774	siderophore transport
BGI46_RS12925	COG1120	ATPase activity
BGI46_RS12935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BGI46_RS12980	COG0730	response to heat
BGI46_RS12995	COG0584	glycerophosphoryl diester phosphodiesterase
BGI46_RS13005	COG1280	lysine exporter protein (LysE YggA)
BGI46_RS13065	COG0604	alcohol dehydrogenase
BGI46_RS13070	COG1733	regulation of RNA biosynthetic process
BGI46_RS13090	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BGI46_RS13110	COG1773	rubredoxin
BGI46_RS13130	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BGI46_RS13205	COG1215	transferase activity, transferring glycosyl groups
BGI46_RS13220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BGI46_RS13235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BGI46_RS13265	COG0859	PFAM glycosyl transferase family 9
BGI46_RS13320	COG1129	ABC transporter
BGI46_RS13330	COG0559	Belongs to the binding-protein-dependent transport system permease family
BGI46_RS13345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BGI46_RS13355	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BGI46_RS13365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BGI46_RS13405	COG2226	methyltransferase
BGI46_RS13435	COG0762	integral membrane protein
BGI46_RS13495	COG0436	Aminotransferase
BGI46_RS13520	COG0653	protein targeting
BGI46_RS13530	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BGI46_RS13530	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BGI46_RS13555	COG2814	Major facilitator Superfamily
BGI46_RS13570	COG1126	abc transporter atp-binding protein
BGI46_RS13575	COG0765	amino acid transport
BGI46_RS13580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BGI46_RS13590	COG0837	glucose binding
BGI46_RS13590	COG1737	Transcriptional regulator
BGI46_RS13595	COG0363	glucosamine-6-phosphate deaminase activity
BGI46_RS13600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BGI46_RS13610	COG1175	transmembrane transport
BGI46_RS13615	COG0395	ABC-type sugar transport system, permease component
BGI46_RS13620	COG3842	ATPase activity
BGI46_RS13625	COG2860	membrane
BGI46_RS13630	COG1193	negative regulation of DNA recombination
BGI46_RS13635	COG0492	ferredoxin-NADP+ reductase activity
BGI46_RS13640	COG1674	ftsk spoiiie
BGI46_RS13645	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BGI46_RS13655	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BGI46_RS13700	COG2894	cell division
BGI46_RS13720	COG0859	PFAM glycosyl transferase family 9
BGI46_RS13730	COG0477	Major facilitator Superfamily
BGI46_RS13765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BGI46_RS13770	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BGI46_RS13780	COG1561	YicC-like family, N-terminal region
BGI46_RS13795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BGI46_RS13815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BGI46_RS13825	COG1278	Cold shock
BGI46_RS13830	COG2176	DNA-directed DNA polymerase activity
BGI46_RS13850	COG4772	TonB-dependent receptor
BGI46_RS13910	COG0583	DNA-binding transcription factor activity
BGI46_RS13920	COG0308	aminopeptidase N
BGI46_RS13935	COG2119	membrane
BGI46_RS13945	COG0402	S-adenosylhomocysteine deaminase activity
BGI46_RS13950	COG2252	PERMEase
BGI46_RS13955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BGI46_RS13975	COG0154	amidase activity
BGI46_RS13985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BGI46_RS14030	COG3383	formate dehydrogenase (NAD+) activity
BGI46_RS14045	COG1910	domain protein
BGI46_RS14055	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BGI46_RS14070	COG0546	phosphoglycolate phosphatase activity
BGI46_RS14100	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BGI46_RS14105	COG0077	Prephenate dehydratase
BGI46_RS14105	COG1605	Chorismate mutase
BGI46_RS14115	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BGI46_RS14140	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BGI46_RS14150	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BGI46_RS14175	COG2951	lytic endotransglycosylase activity
BGI46_RS14180	COG0123	including yeast histone deacetylase and acetoin utilization protein
BGI46_RS14190	COG2267	carboxylic ester hydrolase activity
BGI46_RS14200	COG2011	ABC-type metal ion transport system permease component
BGI46_RS14220	COG1960	acyl-CoA dehydrogenase activity
BGI46_RS14290	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BGI46_RS14305	COG0501	Belongs to the peptidase M48B family
BGI46_RS14315	COG0521	Mo-molybdopterin cofactor biosynthetic process
BGI46_RS14320	COG3028	Belongs to the UPF0307 family
BGI46_RS14330	COG0312	modulator of DNA gyrase
BGI46_RS14340	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BGI46_RS14345	COG2204	response regulator
BGI46_RS14375	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BGI46_RS14385	COG0640	Transcriptional regulator
BGI46_RS14405	COG0114	fumarate hydratase activity
BGI46_RS14420	COG0534	Mate efflux family protein
BGI46_RS14425	COG2501	S4 domain
BGI46_RS14445	COG3045	CreA protein
BGI46_RS14460	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BGI46_RS14470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BGI46_RS14490	COG1322	Protein conserved in bacteria
BGI46_RS14505	COG0303	'Molybdopterin
BGI46_RS14515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BGI46_RS14520	COG1530	ribonuclease E activity
BGI46_RS14535	COG0546	phosphoglycolate phosphatase activity
BGI46_RS14560	COG1399	metal-binding, possibly nucleic acid-binding protein
BGI46_RS14595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BGI46_RS14615	COG3026	antisigma factor binding
BGI46_RS14620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BGI46_RS14640	COG0681	Belongs to the peptidase S26 family
BGI46_RS14645	COG0571	ribonuclease III activity
BGI46_RS14650	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BGI46_RS14660	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BGI46_RS14675	COG2204	response regulator
BGI46_RS14695	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BGI46_RS14720	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BGI46_RS14790	COG1674	ftsk spoiiie
BGI46_RS14950	COG1956	GAF domain-containing protein
BGI46_RS14955	COG0583	DNA-binding transcription factor activity
BGI46_RS14970	COG2153	protein acetylation
BGI46_RS14985	COG1999	signal sequence binding
BGI46_RS15000	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BGI46_RS15005	COG1132	(ABC) transporter
BGI46_RS15010	COG0438	transferase activity, transferring glycosyl groups
BGI46_RS15025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BGI46_RS15030	COG0683	leucine binding
BGI46_RS15040	COG3511	phospholipase C
BGI46_RS15050	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BGI46_RS15060	COG0596	Alpha beta hydrolase
BGI46_RS15070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BGI46_RS15085	COG3394	polysaccharide catabolic process
BGI46_RS15135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BGI46_RS15170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BGI46_RS15180	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BGI46_RS15210	COG1959	2 iron, 2 sulfur cluster binding
BGI46_RS15225	COG2151	metal-sulfur cluster biosynthetic enzyme
BGI46_RS15230	COG0822	iron-sulfur transferase activity
BGI46_RS15235	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BGI46_RS15245	COG0396	ATPase activity
BGI46_RS15250	COG0719	Fe-S assembly protein
BGI46_RS15270	COG0840	transmembrane signaling receptor activity
BGI46_RS15275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BGI46_RS15280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BGI46_RS15300	COG0826	peptidase U32
BGI46_RS15305	COG0826	peptidase U32
BGI46_RS15310	COG3154	lipid carrier protein
BGI46_RS15350	COG2151	metal-sulfur cluster biosynthetic enzyme
BGI46_RS15370	COG0415	Belongs to the DNA photolyase family
BGI46_RS15375	COG0529	Catalyzes the synthesis of activated sulfate
BGI46_RS15425	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BGI46_RS15440	COG0402	S-adenosylhomocysteine deaminase activity
BGI46_RS15475	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BGI46_RS15480	COG0174	glutamine synthetase
BGI46_RS15510	COG0583	DNA-binding transcription factor activity
BGI46_RS15515	COG1960	acyl-CoA dehydrogenase activity
BGI46_RS15530	COG0477	Major facilitator Superfamily
BGI46_RS15540	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BGI46_RS15540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BGI46_RS15545	COG1643	Atp-dependent helicase
BGI46_RS15570	COG1058	Belongs to the CinA family
BGI46_RS15570	COG1546	Belongs to the CinA family
BGI46_RS15585	COG0174	glutamine synthetase
BGI46_RS15605	COG2197	response regulator
BGI46_RS15610	COG4585	Histidine kinase
BGI46_RS15615	COG2181	nitrate reductase activity
BGI46_RS15620	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BGI46_RS15625	COG1140	nitrate reductase beta subunit
BGI46_RS15630	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BGI46_RS15635	COG2223	nitrite transmembrane transporter activity
BGI46_RS15655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BGI46_RS15660	COG0339	signal peptide processing
BGI46_RS15680	COG4566	intracellular signal transduction
BGI46_RS15690	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BGI46_RS15695	COG0508	dehydrogenase complex catalyzes the overall conversion of
BGI46_RS15700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BGI46_RS15720	COG1414	Transcriptional regulator
BGI46_RS15745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BGI46_RS15755	COG1104	cysteine desulfurase activity
BGI46_RS15760	COG0822	iron-sulfur transferase activity
BGI46_RS15765	COG0316	Belongs to the HesB IscA family
BGI46_RS15785	COG2975	iron-sulfur cluster assembly
BGI46_RS15815	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BGI46_RS15835	COG1136	(ABC) transporter
BGI46_RS15840	COG0084	hydrolase, TatD family'
BGI46_RS15845	COG2333	competence protein COMEC
BGI46_RS15845	COG0658	competence protein
BGI46_RS15850	COG2267	carboxylic ester hydrolase activity
BGI46_RS15875	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BGI46_RS15885	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BGI46_RS15895	COG2833	Protein of unknown function (DUF455)
BGI46_RS15905	COG0596	Alpha beta hydrolase
BGI46_RS15915	COG0613	PHP domain protein
BGI46_RS15920	COG0009	L-threonylcarbamoyladenylate synthase
BGI46_RS15925	COG1994	Peptidase M50
BGI46_RS15930	COG0180	Tryptophanyl-tRNA synthetase
BGI46_RS15940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BGI46_RS15945	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BGI46_RS15950	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BGI46_RS15965	COG2850	peptidyl-arginine hydroxylation
BGI46_RS16260	COG3311	Transcriptional regulator
BGI46_RS16305	COG0483	inositol monophosphate 1-phosphatase activity
BGI46_RS16320	COG1045	serine acetyltransferase
BGI46_RS16330	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BGI46_RS16340	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BGI46_RS16365	COG0037	tRNA processing
BGI46_RS16375	COG0527	aspartate kinase activity
BGI46_RS16415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BGI46_RS16435	COG2895	sulfate adenylyltransferase (ATP) activity
BGI46_RS16435	COG0529	Catalyzes the synthesis of activated sulfate
BGI46_RS16440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BGI46_RS16465	COG2175	clavaminate synthase activity
BGI46_RS16485	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BGI46_RS16490	COG3958	Transketolase
BGI46_RS16505	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BGI46_RS16525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BGI46_RS16545	COG0024	Methionine aminopeptidase
BGI46_RS16565	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BGI46_RS16575	COG0243	molybdopterin cofactor binding
BGI46_RS16600	COG4166	transmembrane transport
BGI46_RS16605	COG4174	ABC transporter (Permease)
BGI46_RS16610	COG4239	(ABC) transporter, permease
BGI46_RS16615	COG4172	Belongs to the ABC transporter superfamily
BGI46_RS16625	COG0791	NLP P60 protein
BGI46_RS16630	COG1752	Esterase of the alpha-beta hydrolase superfamily
BGI46_RS16695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BGI46_RS16705	COG0583	DNA-binding transcription factor activity
BGI46_RS16715	COG2224	Isocitrate lyase
BGI46_RS16720	COG0513	Belongs to the DEAD box helicase family
BGI46_RS16730	COG1214	PFAM Peptidase M22, glycoprotease
BGI46_RS16740	COG1573	uracil-dna glycosylase
BGI46_RS16755	COG0351	phosphomethylpyrimidine kinase
BGI46_RS16760	COG0477	Major facilitator Superfamily
BGI46_RS16780	COG0488	(ABC) transporter
BGI46_RS16785	COG0386	Belongs to the glutathione peroxidase family
BGI46_RS16800	COG2890	protein-(glutamine-N5) methyltransferase activity
BGI46_RS16810	COG1393	Belongs to the ArsC family
BGI46_RS16855	COG0242	peptide deformylase activity
BGI46_RS16860	COG1187	pseudouridine synthase activity
BGI46_RS16870	COG0024	Methionine aminopeptidase
BGI46_RS16900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BGI46_RS16915	COG0750	zinc metalloprotease
BGI46_RS16955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BGI46_RS17010	COG0330	HflC and HflK could
BGI46_RS17020	COG2867	negative regulation of translational initiation
BGI46_RS17030	COG0697	spore germination
BGI46_RS17085	COG2814	Major facilitator Superfamily
BGI46_RS17125	COG1619	proteins homologs of microcin C7 resistance protein MccF
BGI46_RS17135	COG1953	Uracil, thiamine, allantoin
BGI46_RS17150	COG3648	Uricase
BGI46_RS17150	COG3195	allantoin biosynthetic process
BGI46_RS17155	COG4266	Belongs to the allantoicase family
BGI46_RS17170	COG2351	hydroxyisourate hydrolase activity
BGI46_RS17185	COG0583	DNA-binding transcription factor activity
BGI46_RS17195	COG3360	Dodecin
BGI46_RS17275	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BGI46_RS17295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BGI46_RS17440	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BGI46_RS17450	COG1846	Transcriptional regulator
BGI46_RS17455	COG1929	Belongs to the glycerate kinase type-1 family
BGI46_RS17480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BGI46_RS17560	COG4181	ATPase activity
BGI46_RS17575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BGI46_RS17585	COG0047	phosphoribosylformylglycinamidine synthase activity
BGI46_RS17585	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BGI46_RS17595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BGI46_RS17620	COG0318	PFAM AMP-dependent synthetase and ligase
BGI46_RS17630	COG1250	3-hydroxyacyl-CoA dehydrogenase
BGI46_RS17630	COG1024	Enoyl-CoA hydratase
BGI46_RS17635	COG1335	isochorismatase
BGI46_RS17640	COG0183	Belongs to the thiolase family
BGI46_RS17665	COG2130	NADP-dependent
BGI46_RS17670	COG0657	acetylesterase activity
BGI46_RS17690	COG0354	folic acid binding
BGI46_RS17695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BGI46_RS17710	COG1247	-acetyltransferase
BGI46_RS17715	COG0084	hydrolase, TatD family'
BGI46_RS17745	COG0438	transferase activity, transferring glycosyl groups
BGI46_RS17775	COG0252	asparaginase activity
BGI46_RS17785	COG1652	LysM domain
BGI46_RS17795	COG2084	Dehydrogenase
BGI46_RS17800	COG3622	Belongs to the hyi family
BGI46_RS17805	COG3960	tartronate-semialdehyde synthase activity
BGI46_RS17810	COG0583	DNA-binding transcription factor activity
BGI46_RS17870	COG0306	phosphate transporter
BGI46_RS17880	COG0791	NLP P60 protein
BGI46_RS17885	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BGI46_RS17895	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BGI46_RS17900	COG0726	polysaccharide deacetylase
BGI46_RS17905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BGI46_RS17905	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BGI46_RS17915	COG0463	Glycosyl transferase, family 2
BGI46_RS17920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BGI46_RS17925	COG2076	Multidrug Resistance protein
BGI46_RS17930	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BGI46_RS17940	COG0436	Aminotransferase
BGI46_RS17970	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BGI46_RS17975	COG0314	molybdopterin synthase activity
BGI46_RS17980	COG2346	COG2346, Truncated hemoglobins
BGI46_RS17985	COG1959	2 iron, 2 sulfur cluster binding
BGI46_RS17990	COG0542	response to heat
BGI46_RS18020	COG0534	Mate efflux family protein
BGI46_RS18040	COG3228	Belongs to the MtfA family
BGI46_RS18045	COG0477	Major facilitator Superfamily
BGI46_RS18050	COG0789	Transcriptional regulator
BGI46_RS18055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BGI46_RS18075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BGI46_RS18090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BGI46_RS18135	COG0670	Belongs to the BI1 family
BGI46_RS18170	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BGI46_RS18185	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BGI46_RS18190	COG0330	HflC and HflK could
BGI46_RS18195	COG0330	HflC and HflK could
BGI46_RS18215	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BGI46_RS18230	COG2183	response to ionizing radiation
BGI46_RS18245	COG1199	ATP-dependent helicase activity
BGI46_RS18255	COG0564	pseudouridine synthase activity
BGI46_RS18260	COG1496	oxidoreductase activity
BGI46_RS18265	COG3243	poly(R)-hydroxyalkanoic acid synthase
BGI46_RS18270	COG0183	Belongs to the thiolase family
BGI46_RS18275	COG1028	Short-chain dehydrogenase reductase Sdr
BGI46_RS18300	COG0183	Belongs to the thiolase family
BGI46_RS18310	COG0626	cystathionine gamma-synthase activity
BGI46_RS18315	COG0560	Phosphoserine phosphatase
BGI46_RS18335	COG0390	transport system, permease component
BGI46_RS18340	COG1122	ATPase activity
BGI46_RS18345	COG2982	Protein involved in outer membrane biogenesis
BGI46_RS18355	COG0488	(ABC) transporter
BGI46_RS18375	COG2070	2-Nitropropane dioxygenase
BGI46_RS18380	COG3047	cAMP biosynthetic process
BGI46_RS18395	COG1914	H( )-stimulated, divalent metal cation uptake system
BGI46_RS18400	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BGI46_RS18405	COG3842	ATPase activity
BGI46_RS18410	COG1176	ABC-type spermidine putrescine transport system, permease component I
BGI46_RS18415	COG1177	transmembrane transport
BGI46_RS18420	COG0730	response to heat
BGI46_RS18420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BGI46_RS18445	COG3655	Transcriptional regulator
BGI46_RS18470	COG1538	Outer membrane efflux protein
BGI46_RS18475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BGI46_RS18490	COG0038	chloride channel
BGI46_RS18495	COG2855	membrane
BGI46_RS18515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BGI46_RS18525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BGI46_RS18535	COG1609	Transcriptional regulator
BGI46_RS18625	COG0598	Magnesium transport protein CorA
BGI46_RS18665	COG3264	Mechanosensitive ion channel
BGI46_RS18665	COG1196	nuclear chromosome segregation
BGI46_RS18700	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BGI46_RS18715	COG4263	nitrous-oxide reductase activity
BGI46_RS18740	COG0840	transmembrane signaling receptor activity
BGI46_RS18750	COG2376	Dihydroxyacetone kinase
BGI46_RS18770	COG0475	glutathione-regulated potassium exporter activity
BGI46_RS18855	COG3121	Chaperone
BGI46_RS18880	COG5295	Hep Hag repeat protein
BGI46_RS18915	COG2197	response regulator
BGI46_RS18995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BGI46_RS19000	COG1012	belongs to the aldehyde dehydrogenase family
BGI46_RS19015	COG1176	ABC-type spermidine putrescine transport system, permease component I
BGI46_RS19025	COG3842	ATPase activity
BGI46_RS19040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BGI46_RS19060	COG2916	Histone family protein nucleoid-structuring protein H-NS
BGI46_RS19090	COG2274	protein secretion by the type I secretion system
BGI46_RS19095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BGI46_RS19105	COG0457	Tetratricopeptide repeat
BGI46_RS19105	COG0859	PFAM glycosyl transferase family 9
BGI46_RS19110	COG0529	Catalyzes the synthesis of activated sulfate
BGI46_RS19115	COG0745	RESPONSE REGULATOR receiver
BGI46_RS19150	COG2963	transposase activity
BGI46_RS19155	COG2801	Transposase and inactivated derivatives
BGI46_RS19165	COG3436	PFAM IS66 Orf2 family protein
BGI46_RS19180	COG1595	DNA-templated transcription, initiation
BGI46_RS19185	COG4944	Protein of unknown function (DUF1109)
BGI46_RS19205	COG3220	belongs to the UPF0276 family
BGI46_RS19235	COG2192	nodulation
BGI46_RS19260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BGI46_RS19280	COG0165	Argininosuccinate lyase
BGI46_RS19285	COG0137	argininosuccinate synthase activity
BGI46_RS19300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BGI46_RS19310	COG3251	PFAM MbtH domain protein
BGI46_RS19330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BGI46_RS19340	COG2207	Transcriptional regulator
BGI46_RS19345	COG0697	spore germination
BGI46_RS19350	COG0835	chemotaxis
BGI46_RS19375	COG0318	PFAM AMP-dependent synthetase and ligase
BGI46_RS19380	COG0477	Major facilitator Superfamily
BGI46_RS19395	COG1732	Glycine betaine
BGI46_RS19400	COG1174	glycine betaine transport
BGI46_RS19405	COG1125	glycine betaine transport
BGI46_RS19410	COG1174	glycine betaine transport
BGI46_RS19430	COG2235	arginine
BGI46_RS19435	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BGI46_RS19460	COG0583	DNA-binding transcription factor activity
BGI46_RS19465	COG0625	glutathione transferase activity
BGI46_RS19485	COG1846	Transcriptional regulator
BGI46_RS19490	COG2807	transmembrane transport
BGI46_RS19495	COG1649	PFAM Uncharacterised BCR, COG1649
BGI46_RS19515	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BGI46_RS19525	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BGI46_RS19545	COG3979	chitinase
BGI46_RS19565	COG0400	carboxylic ester hydrolase activity
BGI46_RS19600	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BGI46_RS19630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BGI46_RS19635	COG4774	siderophore transport
BGI46_RS19640	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BGI46_RS19690	COG1120	ATPase activity
BGI46_RS19720	COG1028	Short-chain dehydrogenase reductase Sdr
BGI46_RS19725	COG1070	Carbohydrate kinase
BGI46_RS19730	COG1063	alcohol dehydrogenase
BGI46_RS19740	COG1172	Belongs to the binding-protein-dependent transport system permease family
BGI46_RS19745	COG1129	ABC transporter
BGI46_RS19750	COG1879	ABC-type sugar transport system periplasmic component
BGI46_RS19775	COG1132	(ABC) transporter
BGI46_RS19775	COG2375	cellular response to nickel ion
BGI46_RS19785	COG3121	Chaperone
BGI46_RS19795	COG3539	Fimbrial protein
BGI46_RS19820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BGI46_RS19830	COG1309	transcriptional regulator
BGI46_RS19840	COG0739	heme binding
BGI46_RS19845	COG0765	amino acid transport
BGI46_RS19850	COG4597	amino acid ABC transporter
BGI46_RS19865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BGI46_RS19910	COG4964	Belongs to the GSP D family
BGI46_RS19935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BGI46_RS19940	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BGI46_RS19955	COG0477	Major facilitator Superfamily
BGI46_RS19965	COG2719	SpoVR family
BGI46_RS19970	COG2718	Belongs to the UPF0229 family
BGI46_RS19975	COG2766	serine protein kinase
BGI46_RS19985	COG0840	transmembrane signaling receptor activity
BGI46_RS19990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BGI46_RS19995	COG1609	Transcriptional regulator
BGI46_RS20000	COG1172	Belongs to the binding-protein-dependent transport system permease family
BGI46_RS20005	COG1129	ABC transporter
BGI46_RS20010	COG1879	ABC-type sugar transport system periplasmic component
BGI46_RS20015	COG0583	DNA-binding transcription factor activity
BGI46_RS20020	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BGI46_RS20025	COG4208	sulfate ABC transporter
BGI46_RS20030	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BGI46_RS20035	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BGI46_RS20085	COG0701	Predicted permease
BGI46_RS20090	COG0667	Aldo Keto reductase
BGI46_RS20115	COG1301	dicarboxylic acid transport
BGI46_RS20165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BGI46_RS20230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BGI46_RS20235	COG0765	amino acid transport
BGI46_RS20240	COG0673	inositol 2-dehydrogenase activity
BGI46_RS20245	COG1802	Transcriptional regulator
BGI46_RS20255	COG3023	N-Acetylmuramoyl-L-alanine amidase
BGI46_RS20265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BGI46_RS20270	COG0557	exoribonuclease II activity
BGI46_RS20285	COG0840	transmembrane signaling receptor activity
BGI46_RS20320	COG0519	Catalyzes the synthesis of GMP from XMP
BGI46_RS20330	COG2814	Major facilitator Superfamily
BGI46_RS20340	COG0318	PFAM AMP-dependent synthetase and ligase
BGI46_RS20410	COG4964	Belongs to the GSP D family
BGI46_RS20470	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BGI46_RS20475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BGI46_RS20480	COG0508	dehydrogenase complex catalyzes the overall conversion of
BGI46_RS20485	COG0567	Dehydrogenase, E1 component
BGI46_RS20500	COG1217	gtp-binding protein TYPA
BGI46_RS20510	COG1846	Transcriptional regulator
BGI46_RS20520	COG1566	PFAM secretion protein HlyD family protein
BGI46_RS20525	COG2814	Major facilitator Superfamily
BGI46_RS20535	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BGI46_RS20550	COG2251	uridine kinase activity
BGI46_RS20550	COG0195	Participates in both transcription termination and antitermination
BGI46_RS20560	COG1187	pseudouridine synthase activity
BGI46_RS20565	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BGI46_RS20570	COG0583	DNA-binding transcription factor activity
BGI46_RS20625	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BGI46_RS20650	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BGI46_RS20650	COG2755	lipolytic protein G-D-S-L family
BGI46_RS20665	COG0776	regulation of translation
BGI46_RS20690	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BGI46_RS20705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BGI46_RS20710	COG0251	oxidation-reduction process
BGI46_RS20715	COG2267	carboxylic ester hydrolase activity
BGI46_RS20725	COG0583	DNA-binding transcription factor activity
BGI46_RS20740	COG1028	Short-chain dehydrogenase reductase Sdr
BGI46_RS20790	COG1028	Short-chain dehydrogenase reductase Sdr
BGI46_RS20815	COG0477	Major facilitator Superfamily
BGI46_RS20840	COG1295	ribonuclease BN
BGI46_RS20855	COG0277	FAD linked oxidase domain protein
BGI46_RS20870	COG0583	DNA-binding transcription factor activity
BGI46_RS20905	COG0840	transmembrane signaling receptor activity
BGI46_RS20910	COG2223	nitrite transmembrane transporter activity
BGI46_RS20915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BGI46_RS20920	COG0210	DNA helicase
BGI46_RS20925	COG0525	valine-tRNA ligase activity
BGI46_RS20930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BGI46_RS20940	COG5002	protein histidine kinase activity
BGI46_RS20950	COG0745	RESPONSE REGULATOR receiver
BGI46_RS20960	COG0425	Belongs to the sulfur carrier protein TusA family
BGI46_RS20970	COG0673	inositol 2-dehydrogenase activity
BGI46_RS20975	COG0673	inositol 2-dehydrogenase activity
BGI46_RS20990	COG1172	Belongs to the binding-protein-dependent transport system permease family
BGI46_RS21005	COG3962	Belongs to the TPP enzyme family
BGI46_RS21015	COG3718	enzyme involved in inositol metabolism
BGI46_RS21025	COG0411	ABC transporter
BGI46_RS21035	COG0824	Thioesterase
BGI46_RS21060	COG2816	NAD+ diphosphatase activity
BGI46_RS21070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BGI46_RS21080	COG0477	Major facilitator Superfamily
BGI46_RS21095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BGI46_RS21105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BGI46_RS21115	COG1051	belongs to the nudix hydrolase family
BGI46_RS21145	COG1858	cytochrome C peroxidase
BGI46_RS21150	COG3511	phospholipase C
BGI46_RS21165	COG1566	PFAM secretion protein HlyD family protein
BGI46_RS21175	COG2814	Major facilitator Superfamily
BGI46_RS21180	COG1538	Outer membrane efflux protein
BGI46_RS21190	COG2197	response regulator
BGI46_RS21680	COG1640	4-alpha-glucanotransferase
BGI46_RS22275	COG1074	ATP-dependent DNA helicase activity
BGI46_RS22325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BGI46_RS22345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BGI46_RS22355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BGI46_RS22625	COG1007	ATP synthesis coupled electron transport
BGI46_RS22865	COG0745	RESPONSE REGULATOR receiver
BGI46_RS22870	COG2205	protein histidine kinase activity
BGI46_RS22890	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BGI46_RS23255	COG3387	PFAM Glycoside hydrolase 15-related
BGI46_RS23495	COG0488	(ABC) transporter
BGI46_RS23745	COG1741	Belongs to the pirin family
BGI46_RS23800	COG2827	Endonuclease containing a URI domain
BGI46_RS23965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BGI46_RS24100	COG1492	cobalamin metabolic process
BGI46_RS24105	COG1492	cobalamin metabolic process
BGI46_RS24150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BGI46_RS24625	COG1570	exodeoxyribonuclease VII activity
BGI46_RS24845	COG1012	belongs to the aldehyde dehydrogenase family
BGI46_RS25080	COG2027	D-alanyl-D-alanine carboxypeptidase
BGI46_RS25125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BGI46_RS25190	COG4783	chaperone-mediated protein folding
BGI46_RS25230	COG0642	Histidine kinase
BGI46_RS25745	COG1960	acyl-CoA dehydrogenase activity
BGI46_RS25855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BGI46_RS25870	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BGI46_RS26065	COG5002	protein histidine kinase activity
BGI46_RS26065	COG5001	Diguanylate cyclase
BGI46_RS26395	COG1194	a g-specific adenine glycosylase
BGI46_RS26475	COG0625	glutathione transferase activity
BGI46_RS26710	COG0587	DNA-directed DNA polymerase activity
BGI46_RS26960	COG0004	ammonium transporteR
BGI46_RS27365	COG0488	(ABC) transporter
BGI46_RS27610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BGI46_RS27715	COG1609	Transcriptional regulator
BGI46_RS27810	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BGI46_RS28060	COG1706	bacterial-type flagellum-dependent cell motility
BGI46_RS28200	COG0601	transmembrane transport
BGI46_RS28900	COG0706	membrane insertase activity
BGI46_RS28940	COG0187	DNA topoisomerase II activity
BGI46_RS29000	COG1024	Enoyl-CoA hydratase
BGI46_RS29000	COG1250	3-hydroxyacyl-CoA dehydrogenase
BGI46_RS29215	COG2814	Major facilitator Superfamily
BGI46_RS29410	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BGI46_RS29470	COG3845	ABC transporter
BGI46_RS29610	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BGI46_RS29610	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BGI46_RS29610	COG0506	proline dehydrogenase activity
BGI46_RS29745	COG0531	amino acid
BGI46_RS29765	COG1012	belongs to the aldehyde dehydrogenase family
BGI46_RS29880	COG0210	DNA helicase
BGI46_RS29900	COG0582	viral genome integration into host DNA
BGI46_RS30090	COG0438	transferase activity, transferring glycosyl groups
BGI46_RS30220	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BGI46_RS30355	COG2801	Transposase and inactivated derivatives
BGI46_RS30620	COG2151	metal-sulfur cluster biosynthetic enzyme
BGI46_RS31090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BGI46_RS31755	COG0546	phosphoglycolate phosphatase activity
BGI46_RS31825	COG0318	PFAM AMP-dependent synthetase and ligase
BGI46_RS31870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BGI46_RS32550	COG2223	nitrite transmembrane transporter activity
BGI46_RS32555	COG2223	nitrite transmembrane transporter activity
BGI46_RS32600	COG0765	amino acid transport
BGI46_RS32765	COG0069	glutamate synthase activity
BGI46_RS32860	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BGI46_RS32870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BGI46_RS33095	COG0312	modulator of DNA gyrase
BGI46_RS33125	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BGI46_RS33130	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BGI46_RS33465	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BGI46_RS34050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BGI46_RS34065	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BGI46_RS34405	COG0395	ABC-type sugar transport system, permease component
BGI46_RS34440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BGI46_RS34750	COG0077	Prephenate dehydratase
BGI46_RS34750	COG1605	Chorismate mutase
BGI46_RS34770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BGI46_RS35115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BGI46_RS35530	COG1132	(ABC) transporter
BGI46_RS36300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BGI46_RS36305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BGI46_RS36360	COG0508	dehydrogenase complex catalyzes the overall conversion of
BGI46_RS36460	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BGI46_RS36990	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BGI46_RS37010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BGI46_RS37225	COG3959	Transketolase, thiamine diphosphate binding domain
BGI46_RS37385	COG4166	transmembrane transport
BGI46_RS37500	COG1573	uracil-dna glycosylase
BGI46_RS37990	COG0583	DNA-binding transcription factor activity
BGI46_RS38385	COG1024	Enoyl-CoA hydratase
BGI46_RS38385	COG1250	3-hydroxyacyl-CoA dehydrogenase