locus-tag	class	description
DP63_RS00450	COG2814	Major facilitator Superfamily
DP63_RS00605	COG0243	molybdopterin cofactor binding
DP63_RS01460	COG3511	phospholipase C
DP63_RS01535	COG0840	transmembrane signaling receptor activity
DP63_RS01635	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DP63_RS01790	COG1706	bacterial-type flagellum-dependent cell motility
DP63_RS01885	COG4608	Belongs to the ABC transporter superfamily
DP63_RS01910	COG0747	negative chemotaxis
DP63_RS02095	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DP63_RS02135	COG1309	transcriptional regulator
DP63_RS02675	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP63_RS02905	COG0642	Histidine kinase
DP63_RS02935	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DP63_RS03190	COG0668	transmembrane transport
DP63_RS03760	COG0281	malic enzyme
DP63_RS03760	COG0280	phosphate acetyltransferase
DP63_RS03810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DP63_RS04195	COG1127	ABC transporter
DP63_RS04225	COG0842	Transport permease protein
DP63_RS04275	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DP63_RS04605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DP63_RS04780	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DP63_RS05355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DP63_RS05430	COG0069	glutamate synthase activity
DP63_RS06735	COG0395	ABC-type sugar transport system, permease component
DP63_RS06740	COG3842	ATPase activity
DP63_RS06760	COG1674	ftsk spoiiie
DP63_RS07265	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DP63_RS07310	COG0114	fumarate hydratase activity
DP63_RS07395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DP63_RS07420	COG3026	antisigma factor binding
DP63_RS07525	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DP63_RS07585	COG0596	Alpha beta hydrolase
DP63_RS08005	COG1643	Atp-dependent helicase
DP63_RS08095	COG2197	response regulator
DP63_RS08120	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DP63_RS08380	COG2267	carboxylic ester hydrolase activity
DP63_RS08875	COG2895	sulfate adenylyltransferase (ATP) activity
DP63_RS08925	COG0243	molybdopterin cofactor binding
DP63_RS08940	COG4166	transmembrane transport
DP63_RS09195	COG0242	peptide deformylase activity
DP63_RS09780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DP63_RS09780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DP63_RS10210	COG0560	Phosphoserine phosphatase
DP63_RS10430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DP63_RS10535	COG4263	nitrous-oxide reductase activity
DP63_RS10575	COG3188	usher protein
DP63_RS10590	COG5295	Hep Hag repeat protein
DP63_RS10600	COG5295	Hep Hag repeat protein
DP63_RS10835	COG3220	belongs to the UPF0276 family
DP63_RS11100	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DP63_RS11540	COG2766	serine protein kinase
DP63_RS11570	COG1129	ABC transporter
DP63_RS11590	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DP63_RS11675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DP63_RS11955	COG0567	Dehydrogenase, E1 component
DP63_RS12115	COG0583	DNA-binding transcription factor activity
DP63_RS12265	COG0210	DNA helicase
DP63_RS13110	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DP63_RS13125	COG3178	'Phosphotransferase
DP63_RS13130	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DP63_RS13140	COG5265	(ABC) transporter
DP63_RS13155	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DP63_RS13160	COG1024	Enoyl-CoA hydratase
DP63_RS13165	COG0183	Belongs to the thiolase family
DP63_RS13170	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP63_RS13170	COG1024	Enoyl-CoA hydratase
DP63_RS13175	COG1960	acyl-CoA dehydrogenase activity
DP63_RS13190	COG0494	nUDIX hydrolase
DP63_RS13250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DP63_RS13260	COG0251	oxidation-reduction process
DP63_RS13265	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DP63_RS13290	COG0477	Major facilitator Superfamily
DP63_RS13325	COG1596	polysaccharide export
DP63_RS13330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DP63_RS13345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DP63_RS13355	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DP63_RS13375	COG2204	response regulator
DP63_RS13410	COG5001	Diguanylate cyclase
DP63_RS13410	COG5002	protein histidine kinase activity
DP63_RS13415	COG0235	Class ii aldolase
DP63_RS13470	COG0142	geranyltranstransferase activity
DP63_RS13535	COG0629	single-stranded DNA binding
DP63_RS13540	COG2814	Major facilitator Superfamily
DP63_RS13565	COG1280	lysine exporter protein (LysE YggA)
DP63_RS13585	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DP63_RS13600	COG1137	ATPase activity
DP63_RS13605	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DP63_RS13610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DP63_RS13635	COG1194	a g-specific adenine glycosylase
DP63_RS13650	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DP63_RS13665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DP63_RS13685	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DP63_RS13695	COG0742	ribosomal rna small subunit methyltransferase
DP63_RS13705	COG0625	glutathione transferase activity
DP63_RS13715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DP63_RS13725	COG0243	molybdopterin cofactor binding
DP63_RS13730	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DP63_RS13740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DP63_RS13750	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DP63_RS13755	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DP63_RS13770	COG1294	oxidase, subunit
DP63_RS13790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP63_RS13790	COG1263	PTS System
DP63_RS13790	COG2190	(PTS) system
DP63_RS13795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DP63_RS13795	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP63_RS13800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DP63_RS13805	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DP63_RS13810	COG2188	Transcriptional regulator
DP63_RS13815	COG0583	DNA-binding transcription factor activity
DP63_RS13860	COG0318	PFAM AMP-dependent synthetase and ligase
DP63_RS13870	COG1960	acyl-CoA dehydrogenase activity
DP63_RS13880	COG2226	methyltransferase
DP63_RS13890	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
DP63_RS13915	COG2814	Major facilitator Superfamily
DP63_RS13925	COG0587	DNA-directed DNA polymerase activity
DP63_RS13940	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DP63_RS13960	COG0840	transmembrane signaling receptor activity
DP63_RS13970	COG1999	signal sequence binding
DP63_RS13980	COG1612	heme a metabolic process
DP63_RS14010	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DP63_RS14020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DP63_RS14035	COG2226	methyltransferase
DP63_RS14040	COG1040	competence protein
DP63_RS14050	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DP63_RS14070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DP63_RS14080	COG0793	Belongs to the peptidase S41A family
DP63_RS14085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DP63_RS14090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DP63_RS14095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP63_RS14105	COG0189	ligase activity
DP63_RS14115	COG0004	ammonium transporteR
DP63_RS14125	COG2960	long-chain fatty acid transporting porin activity
DP63_RS14155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DP63_RS14165	COG4191	Histidine kinase
DP63_RS14175	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DP63_RS14185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DP63_RS14190	COG1960	acyl-CoA dehydrogenase activity
DP63_RS14195	COG1960	acyl-CoA dehydrogenase activity
DP63_RS14200	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP63_RS14200	COG1024	Enoyl-CoA hydratase
DP63_RS14205	COG0583	DNA-binding transcription factor activity
DP63_RS14245	COG0583	DNA-binding transcription factor activity
DP63_RS14250	COG2921	Belongs to the UPF0250 family
DP63_RS14260	COG1686	Belongs to the peptidase S11 family
DP63_RS14295	COG1127	ABC transporter
DP63_RS14300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DP63_RS14305	COG0737	Belongs to the 5'-nucleotidase family
DP63_RS14320	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DP63_RS14330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DP63_RS14350	COG1024	Enoyl-CoA hydratase
DP63_RS14400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DP63_RS14405	COG4221	oxidoreductase activity
DP63_RS14410	COG1028	Short-chain dehydrogenase reductase Sdr
DP63_RS14425	COG0747	negative chemotaxis
DP63_RS14430	COG0488	(ABC) transporter
DP63_RS14445	COG0288	reversible hydration of carbon dioxide
DP63_RS14450	COG0183	Belongs to the thiolase family
DP63_RS14460	COG3012	SEC-C Motif Domain Protein
DP63_RS14480	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DP63_RS14505	COG1785	Belongs to the alkaline phosphatase family
DP63_RS14515	COG2200	EAL domain
DP63_RS14515	COG2199	diguanylate cyclase activity
DP63_RS14520	COG0025	NhaP-type Na H and K H
DP63_RS14550	COG2204	response regulator
DP63_RS14580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DP63_RS14595	COG1999	signal sequence binding
DP63_RS14630	COG3511	phospholipase C
DP63_RS14650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DP63_RS14680	COG0596	Alpha beta hydrolase
DP63_RS14690	COG0583	DNA-binding transcription factor activity
DP63_RS14695	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP63_RS14710	COG0840	transmembrane signaling receptor activity
DP63_RS14715	COG1609	Transcriptional regulator
DP63_RS14770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DP63_RS14790	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP63_RS14795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DP63_RS14815	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DP63_RS14820	COG1704	LemA family
DP63_RS14910	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP63_RS14920	COG2824	Alkylphosphonate utilization operon protein PhnA
DP63_RS14940	COG0583	DNA-binding transcription factor activity
DP63_RS14945	COG2233	PERMEase
DP63_RS14950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DP63_RS14960	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DP63_RS14970	COG1706	bacterial-type flagellum-dependent cell motility
DP63_RS14975	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DP63_RS14990	COG1749	Flagellar hook protein flgE
DP63_RS14995	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DP63_RS15000	COG1558	bacterial-type flagellum-dependent cell motility
DP63_RS15005	COG1815	bacterial-type flagellum-dependent cell motility
DP63_RS15015	COG2747	anti-sigma28 factor FlgM
DP63_RS15045	COG0741	lytic transglycosylase activity
DP63_RS15050	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DP63_RS15060	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DP63_RS15065	COG1984	allophanate hydrolase subunit 2
DP63_RS15095	COG4608	Belongs to the ABC transporter superfamily
DP63_RS15100	COG0444	Belongs to the ABC transporter superfamily
DP63_RS15105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DP63_RS15110	COG0601	transmembrane transport
DP63_RS15115	COG0747	negative chemotaxis
DP63_RS15130	COG0579	oxidoreductase
DP63_RS15150	COG3568	Endonuclease Exonuclease Phosphatase
DP63_RS15155	COG1280	lysine exporter protein (LysE YggA)
DP63_RS15175	COG0531	amino acid
DP63_RS15190	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DP63_RS15250	COG1960	acyl-CoA dehydrogenase activity
DP63_RS15265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DP63_RS15275	COG2814	Major facilitator Superfamily
DP63_RS15290	COG0667	Aldo Keto reductase
DP63_RS15315	COG1560	Kdo2-lipid A biosynthetic process
DP63_RS15330	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DP63_RS15340	COG0523	cobalamin synthesis protein
DP63_RS15360	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DP63_RS15385	COG1309	transcriptional regulator
DP63_RS15400	COG2814	Major facilitator Superfamily
DP63_RS15410	COG2207	Transcriptional regulator
DP63_RS15415	COG1064	alcohol dehydrogenase
DP63_RS15420	COG0708	Exodeoxyribonuclease III
DP63_RS15425	COG2326	polyphosphate kinase activity
DP63_RS15445	COG1077	Cell shape determining protein MreB Mrl
DP63_RS15460	COG0768	penicillin binding
DP63_RS15465	COG0772	Belongs to the SEDS family
DP63_RS15480	COG0720	synthase
DP63_RS15485	COG0602	queuosine metabolic process
DP63_RS15500	COG2204	response regulator
DP63_RS15505	COG5000	phosphorelay sensor kinase activity
DP63_RS15515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DP63_RS15515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DP63_RS15535	COG0242	peptide deformylase activity
DP63_RS15540	COG0758	DNA mediated transformation
DP63_RS15555	COG0583	DNA-binding transcription factor activity
DP63_RS15560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DP63_RS15625	COG2963	transposase activity
DP63_RS15630	COG2801	Transposase and inactivated derivatives
DP63_RS15645	COG4695	Portal protein
DP63_RS15650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DP63_RS15665	COG0583	DNA-binding transcription factor activity
DP63_RS15685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DP63_RS15700	COG2169	Transcriptional regulator
DP63_RS15700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DP63_RS15720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DP63_RS15750	COG2963	transposase activity
DP63_RS15755	COG2801	Transposase and inactivated derivatives
DP63_RS15810	COG0582	viral genome integration into host DNA
DP63_RS15850	COG0592	DNA-directed DNA polymerase activity
DP63_RS15865	COG0753	catalase activity
DP63_RS15905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DP63_RS15910	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP63_RS15910	COG1024	Enoyl-CoA hydratase
DP63_RS15915	COG0183	Belongs to the thiolase family
DP63_RS15925	COG1960	acyl-CoA dehydrogenase activity
DP63_RS15950	COG1695	Transcriptional regulator
DP63_RS16015	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP63_RS16035	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP63_RS16050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DP63_RS16060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DP63_RS16070	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DP63_RS16070	COG4106	trans-aconitate 2-methyltransferase activity
DP63_RS16075	COG0789	Transcriptional regulator
DP63_RS16085	COG1987	bacterial-type flagellum assembly
DP63_RS16100	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DP63_RS16115	COG1346	cytolysis
DP63_RS16125	COG0583	DNA-binding transcription factor activity
DP63_RS16130	COG2814	Major facilitator Superfamily
DP63_RS16135	COG1846	Transcriptional regulator
DP63_RS16180	COG2165	general secretion pathway protein
DP63_RS16195	COG1459	type II secretion system
DP63_RS16215	COG0523	cobalamin synthesis protein
DP63_RS16245	COG0519	Catalyzes the synthesis of GMP from XMP
DP63_RS16245	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DP63_RS16250	COG1902	pentaerythritol trinitrate reductase activity
DP63_RS16265	COG0642	Histidine kinase
DP63_RS16285	COG3186	Phenylalanine-4-hydroxylase
DP63_RS16290	COG1522	sequence-specific DNA binding
DP63_RS16300	COG0583	DNA-binding transcription factor activity
DP63_RS16310	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DP63_RS16330	COG0559	Belongs to the binding-protein-dependent transport system permease family
DP63_RS16370	COG1192	Involved in chromosome partitioning
DP63_RS16375	COG1475	DNA binding
DP63_RS16380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DP63_RS16390	COG0356	it plays a direct role in the translocation of protons across the membrane
DP63_RS16430	COG0318	PFAM AMP-dependent synthetase and ligase
DP63_RS16435	COG1832	CoA-binding protein
DP63_RS16450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DP63_RS16460	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DP63_RS16460	COG0506	proline dehydrogenase activity
DP63_RS16460	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DP63_RS16475	COG1960	acyl-CoA dehydrogenase activity
DP63_RS16485	COG0436	Aminotransferase
DP63_RS16505	COG0277	FAD linked oxidase domain protein
DP63_RS16515	COG0789	Transcriptional regulator
DP63_RS16535	COG0668	transmembrane transport
DP63_RS16555	COG0531	amino acid
DP63_RS16560	COG4303	Ethanolamine ammonia lyase large subunit
DP63_RS16565	COG4302	ethanolamine ammonia-lyase activity
DP63_RS16575	COG1012	belongs to the aldehyde dehydrogenase family
DP63_RS16600	COG1760	l-serine dehydratase
DP63_RS16615	COG0509	glycine decarboxylation via glycine cleavage system
DP63_RS16630	COG0673	inositol 2-dehydrogenase activity
DP63_RS16645	COG0210	DNA helicase
DP63_RS16650	COG3245	cytochrome
DP63_RS16660	COG0582	viral genome integration into host DNA
DP63_RS16685	COG3397	chitin binding
DP63_RS16705	COG2267	carboxylic ester hydrolase activity
DP63_RS16760	COG1028	Short-chain dehydrogenase reductase Sdr
DP63_RS16775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DP63_RS16810	COG0519	Catalyzes the synthesis of GMP from XMP
DP63_RS16820	COG0561	phosphatase activity
DP63_RS16825	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DP63_RS16835	COG0438	transferase activity, transferring glycosyl groups
DP63_RS16855	COG1360	Flagellar Motor Protein
DP63_RS16860	COG2201	protein-glutamate methylesterase activity
DP63_RS16880	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DP63_RS16890	COG2201	protein-glutamate methylesterase activity
DP63_RS16895	COG0745	RESPONSE REGULATOR receiver
DP63_RS16900	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DP63_RS16920	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DP63_RS16925	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DP63_RS16950	COG1950	PFAM Membrane protein of
DP63_RS16955	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DP63_RS16970	COG2070	2-Nitropropane dioxygenase
DP63_RS16995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DP63_RS17000	COG1522	sequence-specific DNA binding
DP63_RS17010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DP63_RS17020	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DP63_RS17030	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DP63_RS17035	COG2823	Periplasmic or secreted lipoprotein
DP63_RS17050	COG1113	amino acid transport
DP63_RS17080	COG2084	Dehydrogenase
DP63_RS17085	COG1280	lysine exporter protein (LysE YggA)
DP63_RS17090	COG2814	Major facilitator Superfamily
DP63_RS17095	COG0583	DNA-binding transcription factor activity
DP63_RS17100	COG3047	cAMP biosynthetic process
DP63_RS17115	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DP63_RS17125	COG1881	PFAM PEBP family protein
DP63_RS17130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DP63_RS17135	COG0281	malic enzyme
DP63_RS17135	COG0280	phosphate acetyltransferase
DP63_RS17155	COG1522	sequence-specific DNA binding
DP63_RS17175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DP63_RS17180	COG2151	metal-sulfur cluster biosynthetic enzyme
DP63_RS17185	COG3396	Phenylacetate-CoA oxygenase
DP63_RS17190	COG3460	Phenylacetate-CoA oxygenase
DP63_RS17195	COG3396	Phenylacetate-CoA oxygenase
DP63_RS17255	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DP63_RS17300	COG0514	ATP-dependent DNA helicase (RecQ)
DP63_RS17430	COG0201	protein transport
DP63_RS17475	COG4232	protein-disulfide reductase activity
DP63_RS17495	COG1333	cytochrome c biogenesis protein
DP63_RS17500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DP63_RS17505	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DP63_RS17510	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DP63_RS17565	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DP63_RS17575	COG1175	transmembrane transport
DP63_RS17580	COG0395	ABC-type sugar transport system, permease component
DP63_RS17585	COG3842	ATPase activity
DP63_RS17590	COG0584	glycerophosphoryl diester phosphodiesterase
DP63_RS17605	COG0067	glutamate synthase
DP63_RS17605	COG0069	glutamate synthase activity
DP63_RS17605	COG0070	glutamate synthase
DP63_RS17615	COG1115	amino acid carrier protein
DP63_RS17625	COG4178	(ABC) transporter
DP63_RS17650	COG1127	ABC transporter
DP63_RS17655	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DP63_RS17660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DP63_RS17680	COG1131	(ABC) transporter
DP63_RS17685	COG0842	Transport permease protein
DP63_RS17705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DP63_RS17710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DP63_RS17720	COG2095	MarC family integral membrane protein
DP63_RS17770	COG0805	protein transport
DP63_RS17780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP63_RS17785	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DP63_RS17790	COG0723	plastoquinol--plastocyanin reductase activity
DP63_RS17795	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DP63_RS17800	COG2857	Cytochrome c1
DP63_RS17805	COG0625	glutathione transferase activity
DP63_RS17810	COG2969	positive regulation of protein catabolic process
DP63_RS17820	COG0464	growth
DP63_RS17825	COG2963	transposase activity
DP63_RS17830	COG2801	Transposase and inactivated derivatives
DP63_RS17980	COG0308	aminopeptidase N
DP63_RS18025	COG0443	Heat shock 70 kDa protein
DP63_RS18030	COG1278	Cold shock
DP63_RS18035	COG0531	amino acid
DP63_RS18040	COG3384	dioxygenase
DP63_RS18050	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DP63_RS18055	COG2890	protein-(glutamine-N5) methyltransferase activity
DP63_RS18080	COG0006	proline dipeptidase activity
DP63_RS18090	COG1335	isochorismatase
DP63_RS18100	COG0488	(ABC) transporter
DP63_RS18115	COG0584	glycerophosphoryl diester phosphodiesterase
DP63_RS18145	COG0012	GTP binding
DP63_RS18160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DP63_RS18165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DP63_RS18180	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DP63_RS18200	COG0512	Glutamine amidotransferase of anthranilate synthase
DP63_RS18210	COG0546	phosphoglycolate phosphatase activity
DP63_RS18215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DP63_RS18220	COG2967	ApaG domain
DP63_RS18230	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DP63_RS18240	COG2050	protein possibly involved in aromatic compounds catabolism
DP63_RS18245	COG1024	Enoyl-CoA hydratase
DP63_RS18250	COG0183	Belongs to the thiolase family
DP63_RS18260	COG1024	Enoyl-CoA hydratase
DP63_RS18290	COG0243	molybdopterin cofactor binding
DP63_RS18295	COG0318	PFAM AMP-dependent synthetase and ligase
DP63_RS18300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP63_RS18320	COG3116	cell division
DP63_RS18330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DP63_RS18335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DP63_RS18370	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DP63_RS18385	COG0678	peroxiredoxin activity
DP63_RS18415	COG0494	nUDIX hydrolase
DP63_RS18420	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DP63_RS18435	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DP63_RS18445	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DP63_RS18450	COG4536	flavin adenine dinucleotide binding
DP63_RS18545	COG0142	geranyltranstransferase activity
DP63_RS18585	COG2095	MarC family integral membrane protein
DP63_RS18590	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DP63_RS18595	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DP63_RS18640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DP63_RS18645	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DP63_RS18660	COG0439	Biotin carboxylase
DP63_RS18665	COG0511	ligase activity, forming carbon-carbon bonds
DP63_RS18670	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DP63_RS18675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DP63_RS18685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DP63_RS18690	COG3150	esterase
DP63_RS18695	COG0557	exoribonuclease II activity
DP63_RS18700	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DP63_RS18705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DP63_RS18720	COG1414	Transcriptional regulator
DP63_RS18725	COG3734	2-keto-3-deoxy-galactonokinase
DP63_RS18735	COG1028	Short-chain dehydrogenase reductase Sdr
DP63_RS18750	COG1172	Belongs to the binding-protein-dependent transport system permease family
DP63_RS18755	COG1028	Short-chain dehydrogenase reductase Sdr
DP63_RS18765	COG0284	orotidine-5'-phosphate decarboxylase activity
DP63_RS18770	COG1546	Belongs to the CinA family
DP63_RS18775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DP63_RS18805	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DP63_RS18815	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DP63_RS18820	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DP63_RS18825	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DP63_RS18830	COG2814	Major facilitator Superfamily
DP63_RS18845	COG0583	DNA-binding transcription factor activity
DP63_RS18855	COG1301	dicarboxylic acid transport
DP63_RS18860	COG4266	Belongs to the allantoicase family
DP63_RS18865	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DP63_RS18870	COG0735	belongs to the Fur family
DP63_RS18875	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DP63_RS18905	COG1466	dna polymerase III delta subunit
DP63_RS18910	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DP63_RS18915	COG1981	membrane
DP63_RS18920	COG0837	glucose binding
DP63_RS18920	COG1737	Transcriptional regulator
DP63_RS18930	COG0800	Aldolase
DP63_RS18950	COG2223	nitrite transmembrane transporter activity
DP63_RS18955	COG0583	DNA-binding transcription factor activity
DP63_RS18960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DP63_RS18965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP63_RS18970	COG0765	amino acid transport
DP63_RS18975	COG0765	amino acid transport
DP63_RS18980	COG1126	abc transporter atp-binding protein
DP63_RS19015	COG0121	glutamine amidotransferase
DP63_RS19020	COG0418	dihydroorotase activity
DP63_RS19050	COG4977	sequence-specific DNA binding
DP63_RS19050	COG1917	Cupin 2, conserved barrel domain protein
DP63_RS19055	COG0625	glutathione transferase activity
DP63_RS19060	COG0625	glutathione transferase activity
DP63_RS19070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DP63_RS19080	COG0588	phosphoglycerate mutase activity
DP63_RS19115	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DP63_RS19120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DP63_RS19125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DP63_RS19130	COG0006	proline dipeptidase activity
DP63_RS19135	COG0625	glutathione transferase activity
DP63_RS19140	COG0069	glutamate synthase activity
DP63_RS19210	COG3008	intermembrane lipid transfer
DP63_RS19210	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DP63_RS19215	COG2995	paraquat-inducible protein a
DP63_RS19235	COG2353	YceI-like domain
DP63_RS19240	COG2353	YceI-like domain
DP63_RS19250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DP63_RS19255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DP63_RS19260	COG1862	Preprotein translocase
DP63_RS19265	COG0343	queuine tRNA-ribosyltransferase activity
DP63_RS19275	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DP63_RS19295	COG0783	Belongs to the Dps family
DP63_RS19315	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DP63_RS19320	COG2188	Transcriptional regulator
DP63_RS19325	COG3624	Phosphonate C-P lyase system protein PhnG
DP63_RS19335	COG3626	phosphonate metabolism
DP63_RS19340	COG3627	carbon phosphorus lyase activity
DP63_RS19345	COG4107	phosphonate C-P lyase system protein PhnK
DP63_RS19350	COG4778	phosphonate C-P lyase system protein PhnL
DP63_RS19355	COG3454	Phosphonate metabolism
DP63_RS19360	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DP63_RS19365	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DP63_RS19370	COG3639	organic phosphonate transmembrane transporter activity
DP63_RS19390	COG0247	lactate metabolic process
DP63_RS19395	COG0277	FAD linked oxidase domain protein
DP63_RS19400	COG0277	FAD linked oxidase domain protein
DP63_RS19405	COG0277	FAD linked oxidase domain protein
DP63_RS19410	COG2096	Adenosyltransferase
DP63_RS19415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DP63_RS19415	COG1017	nitric oxide dioxygenase activity
DP63_RS19420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DP63_RS19425	COG0312	modulator of DNA gyrase
DP63_RS19430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DP63_RS19435	COG3164	Protein of unknown function
DP63_RS19440	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DP63_RS19445	COG0497	DNA recombination
DP63_RS19450	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DP63_RS19490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DP63_RS19500	COG1428	Deoxynucleoside kinase
DP63_RS19505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DP63_RS19510	COG0617	tRNA 3'-terminal CCA addition
DP63_RS19520	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DP63_RS19545	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DP63_RS19550	COG0586	Pfam SNARE associated Golgi protein
DP63_RS19650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DP63_RS19665	COG1368	sulfuric ester hydrolase activity
DP63_RS19670	COG1028	Short-chain dehydrogenase reductase Sdr
DP63_RS19670	COG0604	alcohol dehydrogenase
DP63_RS19670	COG3321	synthase
DP63_RS19675	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DP63_RS19680	COG0156	8-amino-7-oxononanoate synthase activity
DP63_RS19720	COG1596	polysaccharide export
DP63_RS19725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DP63_RS19730	COG3206	protein involved in exopolysaccharide biosynthesis
DP63_RS19730	COG0489	protein tyrosine kinase activity
DP63_RS19740	COG3562	capsule polysaccharide
DP63_RS19745	COG1045	serine acetyltransferase
DP63_RS19760	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DP63_RS19765	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DP63_RS19770	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DP63_RS19770	COG0517	IMP dehydrogenase activity
DP63_RS19805	COG2885	chlorophyll binding
DP63_RS19830	COG0824	Thioesterase
DP63_RS19835	COG4221	oxidoreductase activity
DP63_RS19890	COG0450	alkyl hydroperoxide reductase
DP63_RS19900	COG1960	acyl-CoA dehydrogenase activity
DP63_RS19925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DP63_RS19935	COG2814	Major facilitator Superfamily
DP63_RS19955	COG2814	Major facilitator Superfamily
DP63_RS19960	COG0778	Nitroreductase
DP63_RS19965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DP63_RS19970	COG0583	DNA-binding transcription factor activity
DP63_RS19980	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DP63_RS20010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DP63_RS20025	COG4774	siderophore transport
DP63_RS20030	COG1120	ATPase activity
DP63_RS20040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DP63_RS20080	COG0730	response to heat
DP63_RS20090	COG0584	glycerophosphoryl diester phosphodiesterase
DP63_RS20100	COG1280	lysine exporter protein (LysE YggA)
DP63_RS20150	COG0604	alcohol dehydrogenase
DP63_RS20155	COG1733	regulation of RNA biosynthetic process
DP63_RS20165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DP63_RS20180	COG1773	rubredoxin
DP63_RS20200	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DP63_RS20275	COG1215	transferase activity, transferring glycosyl groups
DP63_RS20290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DP63_RS20305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DP63_RS20330	COG0859	PFAM glycosyl transferase family 9
DP63_RS20385	COG1129	ABC transporter
DP63_RS20395	COG0559	Belongs to the binding-protein-dependent transport system permease family
DP63_RS20405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DP63_RS20415	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DP63_RS20460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DP63_RS20465	COG2226	methyltransferase
DP63_RS20485	COG0762	integral membrane protein
DP63_RS20520	COG0436	Aminotransferase
DP63_RS20545	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DP63_RS20545	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DP63_RS20565	COG2814	Major facilitator Superfamily
DP63_RS20580	COG1126	abc transporter atp-binding protein
DP63_RS20585	COG0765	amino acid transport
DP63_RS20590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP63_RS20595	COG1737	Transcriptional regulator
DP63_RS20595	COG0837	glucose binding
DP63_RS20600	COG0363	glucosamine-6-phosphate deaminase activity
DP63_RS20605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DP63_RS20615	COG1175	transmembrane transport
DP63_RS20620	COG0395	ABC-type sugar transport system, permease component
DP63_RS20625	COG3842	ATPase activity
DP63_RS20630	COG2860	membrane
DP63_RS20635	COG1193	negative regulation of DNA recombination
DP63_RS20640	COG0492	ferredoxin-NADP+ reductase activity
DP63_RS20645	COG1674	ftsk spoiiie
DP63_RS20650	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DP63_RS20655	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DP63_RS20690	COG2894	cell division
DP63_RS20715	COG0859	PFAM glycosyl transferase family 9
DP63_RS20725	COG0477	Major facilitator Superfamily
DP63_RS20755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DP63_RS20760	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DP63_RS20770	COG1561	YicC-like family, N-terminal region
DP63_RS20785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DP63_RS20810	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP63_RS20820	COG1278	Cold shock
DP63_RS20825	COG2176	DNA-directed DNA polymerase activity
DP63_RS20845	COG4772	TonB-dependent receptor
DP63_RS20895	COG0583	DNA-binding transcription factor activity
DP63_RS20905	COG0308	aminopeptidase N
DP63_RS20915	COG2119	membrane
DP63_RS20920	COG0402	S-adenosylhomocysteine deaminase activity
DP63_RS20925	COG2252	PERMEase
DP63_RS20930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DP63_RS20945	COG0154	amidase activity
DP63_RS20950	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DP63_RS20975	COG3383	formate dehydrogenase (NAD+) activity
DP63_RS20990	COG1910	domain protein
DP63_RS21000	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DP63_RS21005	COG0546	phosphoglycolate phosphatase activity
DP63_RS21030	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DP63_RS21035	COG1605	Chorismate mutase
DP63_RS21035	COG0077	Prephenate dehydratase
DP63_RS21040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DP63_RS21070	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DP63_RS21080	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DP63_RS21105	COG2951	lytic endotransglycosylase activity
DP63_RS21110	COG0123	including yeast histone deacetylase and acetoin utilization protein
DP63_RS21115	COG2267	carboxylic ester hydrolase activity
DP63_RS21125	COG2011	ABC-type metal ion transport system permease component
DP63_RS21130	COG1464	Belongs to the NlpA lipoprotein family
DP63_RS21145	COG1960	acyl-CoA dehydrogenase activity
DP63_RS21205	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DP63_RS21220	COG0501	Belongs to the peptidase M48B family
DP63_RS21230	COG0521	Mo-molybdopterin cofactor biosynthetic process
DP63_RS21235	COG3028	Belongs to the UPF0307 family
DP63_RS21240	COG0312	modulator of DNA gyrase
DP63_RS21245	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DP63_RS21250	COG2204	response regulator
DP63_RS21270	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DP63_RS21285	COG0640	Transcriptional regulator
DP63_RS21300	COG0114	fumarate hydratase activity
DP63_RS21310	COG0534	Mate efflux family protein
DP63_RS21315	COG2501	S4 domain
DP63_RS21330	COG3045	CreA protein
DP63_RS21345	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DP63_RS21350	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DP63_RS21365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DP63_RS21370	COG1322	Protein conserved in bacteria
DP63_RS21385	COG0303	'Molybdopterin
DP63_RS21395	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DP63_RS21400	COG1530	ribonuclease E activity
DP63_RS21410	COG0546	phosphoglycolate phosphatase activity
DP63_RS21435	COG1399	metal-binding, possibly nucleic acid-binding protein
DP63_RS21470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DP63_RS21490	COG3026	antisigma factor binding
DP63_RS21495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP63_RS21510	COG0681	Belongs to the peptidase S26 family
DP63_RS21515	COG0571	ribonuclease III activity
DP63_RS21520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DP63_RS21530	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DP63_RS21545	COG2204	response regulator
DP63_RS21565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DP63_RS21585	COG1956	GAF domain-containing protein
DP63_RS21590	COG0583	DNA-binding transcription factor activity
DP63_RS21600	COG2153	protein acetylation
DP63_RS21615	COG1999	signal sequence binding
DP63_RS21630	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DP63_RS21635	COG1132	(ABC) transporter
DP63_RS21640	COG0438	transferase activity, transferring glycosyl groups
DP63_RS21655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DP63_RS21660	COG0683	leucine binding
DP63_RS21665	COG3511	phospholipase C
DP63_RS21675	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DP63_RS21680	COG0596	Alpha beta hydrolase
DP63_RS21685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DP63_RS21700	COG3394	polysaccharide catabolic process
DP63_RS21735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DP63_RS21770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP63_RS21780	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DP63_RS21810	COG1959	2 iron, 2 sulfur cluster binding
DP63_RS21820	COG2151	metal-sulfur cluster biosynthetic enzyme
DP63_RS21825	COG0822	iron-sulfur transferase activity
DP63_RS21830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DP63_RS21840	COG0396	ATPase activity
DP63_RS21845	COG0719	Fe-S assembly protein
DP63_RS21855	COG0840	transmembrane signaling receptor activity
DP63_RS21860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DP63_RS21865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DP63_RS21880	COG0826	peptidase U32
DP63_RS21885	COG0826	peptidase U32
DP63_RS21890	COG3154	lipid carrier protein
DP63_RS21925	COG2151	metal-sulfur cluster biosynthetic enzyme
DP63_RS21940	COG0415	Belongs to the DNA photolyase family
DP63_RS21945	COG0529	Catalyzes the synthesis of activated sulfate
DP63_RS21980	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DP63_RS21995	COG0402	S-adenosylhomocysteine deaminase activity
DP63_RS22020	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DP63_RS22025	COG0174	glutamine synthetase
DP63_RS22055	COG0583	DNA-binding transcription factor activity
DP63_RS22060	COG1960	acyl-CoA dehydrogenase activity
DP63_RS22070	COG0477	Major facilitator Superfamily
DP63_RS22080	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DP63_RS22080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DP63_RS22085	COG1643	Atp-dependent helicase
DP63_RS22105	COG1058	Belongs to the CinA family
DP63_RS22105	COG1546	Belongs to the CinA family
DP63_RS22115	COG0174	glutamine synthetase
DP63_RS22135	COG2197	response regulator
DP63_RS22140	COG4585	Histidine kinase
DP63_RS22145	COG2181	nitrate reductase activity
DP63_RS22150	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DP63_RS22155	COG1140	nitrate reductase beta subunit
DP63_RS22160	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DP63_RS22165	COG2223	nitrite transmembrane transporter activity
DP63_RS22180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DP63_RS22185	COG0339	signal peptide processing
DP63_RS22195	COG4566	intracellular signal transduction
DP63_RS22205	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DP63_RS22210	COG0508	dehydrogenase complex catalyzes the overall conversion of
DP63_RS22215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DP63_RS22235	COG1414	Transcriptional regulator
DP63_RS22240	COG0247	lactate metabolic process
DP63_RS22265	COG1104	cysteine desulfurase activity
DP63_RS22270	COG0822	iron-sulfur transferase activity
DP63_RS22275	COG0316	Belongs to the HesB IscA family
DP63_RS22295	COG2975	iron-sulfur cluster assembly
DP63_RS22315	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DP63_RS22330	COG1136	(ABC) transporter
DP63_RS22335	COG0084	hydrolase, TatD family'
DP63_RS22340	COG2333	competence protein COMEC
DP63_RS22340	COG0658	competence protein
DP63_RS22345	COG2267	carboxylic ester hydrolase activity
DP63_RS22365	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DP63_RS22375	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DP63_RS22385	COG2833	Protein of unknown function (DUF455)
DP63_RS22390	COG2267	carboxylic ester hydrolase activity
DP63_RS22395	COG0613	PHP domain protein
DP63_RS22400	COG0009	L-threonylcarbamoyladenylate synthase
DP63_RS22405	COG1994	Peptidase M50
DP63_RS22410	COG0180	Tryptophanyl-tRNA synthetase
DP63_RS22420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DP63_RS22425	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DP63_RS22430	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DP63_RS22435	COG2850	peptidyl-arginine hydroxylation
DP63_RS22715	COG3311	Transcriptional regulator
DP63_RS22745	COG0483	inositol monophosphate 1-phosphatase activity
DP63_RS22755	COG1045	serine acetyltransferase
DP63_RS22760	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DP63_RS22770	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DP63_RS22795	COG0037	tRNA processing
DP63_RS22800	COG0527	aspartate kinase activity
DP63_RS22830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP63_RS22840	COG2895	sulfate adenylyltransferase (ATP) activity
DP63_RS22840	COG0529	Catalyzes the synthesis of activated sulfate
DP63_RS22845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DP63_RS22870	COG2175	clavaminate synthase activity
DP63_RS22890	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DP63_RS22895	COG3958	Transketolase
DP63_RS22910	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DP63_RS22930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DP63_RS22945	COG0024	Methionine aminopeptidase
DP63_RS22965	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DP63_RS22975	COG0243	molybdopterin cofactor binding
DP63_RS22995	COG4166	transmembrane transport
DP63_RS23000	COG4174	ABC transporter (Permease)
DP63_RS23005	COG4239	(ABC) transporter, permease
DP63_RS23010	COG4172	Belongs to the ABC transporter superfamily
DP63_RS23015	COG0791	NLP P60 protein
DP63_RS23020	COG1752	Esterase of the alpha-beta hydrolase superfamily
DP63_RS23075	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DP63_RS23085	COG0583	DNA-binding transcription factor activity
DP63_RS23095	COG2224	Isocitrate lyase
DP63_RS23100	COG0513	Belongs to the DEAD box helicase family
DP63_RS23110	COG1214	PFAM Peptidase M22, glycoprotease
DP63_RS23120	COG1573	uracil-dna glycosylase
DP63_RS23135	COG0351	phosphomethylpyrimidine kinase
DP63_RS23140	COG0477	Major facilitator Superfamily
DP63_RS23160	COG0488	(ABC) transporter
DP63_RS23165	COG0386	Belongs to the glutathione peroxidase family
DP63_RS23180	COG2890	protein-(glutamine-N5) methyltransferase activity
DP63_RS23190	COG1393	Belongs to the ArsC family
DP63_RS23230	COG0242	peptide deformylase activity
DP63_RS23235	COG1187	pseudouridine synthase activity
DP63_RS23245	COG0024	Methionine aminopeptidase
DP63_RS23275	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DP63_RS23290	COG0750	zinc metalloprotease
DP63_RS23330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DP63_RS23360	COG0330	HflC and HflK could
DP63_RS23370	COG2867	negative regulation of translational initiation
DP63_RS23380	COG0697	spore germination
DP63_RS23440	COG1196	nuclear chromosome segregation
DP63_RS23450	COG2814	Major facilitator Superfamily
DP63_RS23470	COG1619	proteins homologs of microcin C7 resistance protein MccF
DP63_RS23480	COG1953	Uracil, thiamine, allantoin
DP63_RS23495	COG3195	allantoin biosynthetic process
DP63_RS23495	COG3648	Uricase
DP63_RS23500	COG4266	Belongs to the allantoicase family
DP63_RS23515	COG2351	hydroxyisourate hydrolase activity
DP63_RS23525	COG0583	DNA-binding transcription factor activity
DP63_RS23535	COG3360	Dodecin
DP63_RS23595	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DP63_RS23610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DP63_RS23720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DP63_RS23725	COG1846	Transcriptional regulator
DP63_RS23730	COG1929	Belongs to the glycerate kinase type-1 family
DP63_RS23750	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DP63_RS23805	COG4181	ATPase activity
DP63_RS23825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DP63_RS23835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DP63_RS23835	COG0047	phosphoribosylformylglycinamidine synthase activity
DP63_RS23845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DP63_RS23870	COG0318	PFAM AMP-dependent synthetase and ligase
DP63_RS23875	COG1024	Enoyl-CoA hydratase
DP63_RS23875	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP63_RS23880	COG1335	isochorismatase
DP63_RS23885	COG0183	Belongs to the thiolase family
DP63_RS23905	COG2130	NADP-dependent
DP63_RS23910	COG0657	acetylesterase activity
DP63_RS23925	COG0354	folic acid binding
DP63_RS23930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DP63_RS23945	COG1247	-acetyltransferase
DP63_RS23950	COG0084	hydrolase, TatD family'
DP63_RS23975	COG0438	transferase activity, transferring glycosyl groups
DP63_RS23995	COG0252	asparaginase activity
DP63_RS24005	COG1652	LysM domain
DP63_RS24015	COG2084	Dehydrogenase
DP63_RS24020	COG3622	Belongs to the hyi family
DP63_RS24025	COG3960	tartronate-semialdehyde synthase activity
DP63_RS24030	COG0583	DNA-binding transcription factor activity
DP63_RS24045	COG1595	DNA-templated transcription, initiation
DP63_RS24085	COG0306	phosphate transporter
DP63_RS24090	COG0791	NLP P60 protein
DP63_RS24095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DP63_RS24100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DP63_RS24105	COG0726	polysaccharide deacetylase
DP63_RS24110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DP63_RS24110	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DP63_RS24120	COG0463	Glycosyl transferase, family 2
DP63_RS24125	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DP63_RS24130	COG2076	Multidrug Resistance protein
DP63_RS24135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DP63_RS24145	COG0436	Aminotransferase
DP63_RS24165	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DP63_RS24170	COG0314	molybdopterin synthase activity
DP63_RS24175	COG2346	COG2346, Truncated hemoglobins
DP63_RS24180	COG1959	2 iron, 2 sulfur cluster binding
DP63_RS24185	COG0542	response to heat
DP63_RS24210	COG0534	Mate efflux family protein
DP63_RS24225	COG3228	Belongs to the MtfA family
DP63_RS24230	COG0477	Major facilitator Superfamily
DP63_RS24235	COG0789	Transcriptional regulator
DP63_RS24240	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DP63_RS24255	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DP63_RS24270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DP63_RS24315	COG0670	Belongs to the BI1 family
DP63_RS24350	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DP63_RS24365	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DP63_RS24370	COG0330	HflC and HflK could
DP63_RS24375	COG0330	HflC and HflK could
DP63_RS24395	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DP63_RS24405	COG2183	response to ionizing radiation
DP63_RS24420	COG1199	ATP-dependent helicase activity
DP63_RS24430	COG0564	pseudouridine synthase activity
DP63_RS24440	COG3243	poly(R)-hydroxyalkanoic acid synthase
DP63_RS24445	COG0183	Belongs to the thiolase family
DP63_RS24450	COG1028	Short-chain dehydrogenase reductase Sdr
DP63_RS24470	COG0183	Belongs to the thiolase family
DP63_RS24480	COG0626	cystathionine gamma-synthase activity
DP63_RS24485	COG0560	Phosphoserine phosphatase
DP63_RS24500	COG0390	transport system, permease component
DP63_RS24505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DP63_RS24510	COG2982	Protein involved in outer membrane biogenesis
DP63_RS24520	COG0488	(ABC) transporter
DP63_RS24535	COG2070	2-Nitropropane dioxygenase
DP63_RS24540	COG3047	cAMP biosynthetic process
DP63_RS24550	COG1914	H( )-stimulated, divalent metal cation uptake system
DP63_RS24555	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DP63_RS24560	COG3842	ATPase activity
DP63_RS24565	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP63_RS24570	COG1177	transmembrane transport
DP63_RS24575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP63_RS24575	COG0730	response to heat
DP63_RS24600	COG3655	Transcriptional regulator
DP63_RS24620	COG1538	Outer membrane efflux protein
DP63_RS24625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP63_RS24640	COG0038	chloride channel
DP63_RS24645	COG2855	membrane
DP63_RS24665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DP63_RS24675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DP63_RS24680	COG1609	Transcriptional regulator
DP63_RS24765	COG0598	Magnesium transport protein CorA
DP63_RS24795	COG3264	Mechanosensitive ion channel
DP63_RS24795	COG1196	nuclear chromosome segregation
DP63_RS24825	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DP63_RS24840	COG4263	nitrous-oxide reductase activity
DP63_RS24860	COG0840	transmembrane signaling receptor activity
DP63_RS24870	COG2376	Dihydroxyacetone kinase
DP63_RS24890	COG0475	glutathione-regulated potassium exporter activity
DP63_RS24945	COG3121	Chaperone
DP63_RS24950	COG3188	usher protein
DP63_RS24980	COG5295	Hep Hag repeat protein
DP63_RS24995	COG2197	response regulator
DP63_RS25060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DP63_RS25065	COG1012	belongs to the aldehyde dehydrogenase family
DP63_RS25080	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP63_RS25090	COG3842	ATPase activity
DP63_RS25105	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP63_RS25115	COG2916	Histone family protein nucleoid-structuring protein H-NS
DP63_RS25145	COG2274	protein secretion by the type I secretion system
DP63_RS25150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DP63_RS25160	COG0457	Tetratricopeptide repeat
DP63_RS25160	COG0859	PFAM glycosyl transferase family 9
DP63_RS25170	COG0529	Catalyzes the synthesis of activated sulfate
DP63_RS25175	COG0745	RESPONSE REGULATOR receiver
DP63_RS25180	COG2963	transposase activity
DP63_RS25185	COG2801	Transposase and inactivated derivatives
DP63_RS25215	COG2963	transposase activity
DP63_RS25220	COG2801	Transposase and inactivated derivatives
DP63_RS25225	COG3436	PFAM IS66 Orf2 family protein
DP63_RS25235	COG1595	DNA-templated transcription, initiation
DP63_RS25240	COG4944	Protein of unknown function (DUF1109)
DP63_RS25260	COG3220	belongs to the UPF0276 family
DP63_RS25285	COG2192	nodulation
DP63_RS25310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DP63_RS25330	COG0165	Argininosuccinate lyase
DP63_RS25335	COG0137	argininosuccinate synthase activity
DP63_RS25350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DP63_RS25360	COG3251	PFAM MbtH domain protein
DP63_RS25375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP63_RS25380	COG2207	Transcriptional regulator
DP63_RS25385	COG0697	spore germination
DP63_RS25390	COG0835	chemotaxis
DP63_RS25410	COG0318	PFAM AMP-dependent synthetase and ligase
DP63_RS25415	COG0477	Major facilitator Superfamily
DP63_RS25425	COG1732	Glycine betaine
DP63_RS25430	COG1174	glycine betaine transport
DP63_RS25435	COG1125	glycine betaine transport
DP63_RS25440	COG1174	glycine betaine transport
DP63_RS25455	COG2235	arginine
DP63_RS25460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DP63_RS25485	COG0583	DNA-binding transcription factor activity
DP63_RS25490	COG0625	glutathione transferase activity
DP63_RS25505	COG1846	Transcriptional regulator
DP63_RS25510	COG2807	transmembrane transport
DP63_RS25515	COG1649	PFAM Uncharacterised BCR, COG1649
DP63_RS25535	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DP63_RS25545	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DP63_RS25565	COG3979	chitinase
DP63_RS25580	COG0400	carboxylic ester hydrolase activity
DP63_RS25610	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DP63_RS25635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DP63_RS25640	COG4774	siderophore transport
DP63_RS25645	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DP63_RS25690	COG1120	ATPase activity
DP63_RS25720	COG1028	Short-chain dehydrogenase reductase Sdr
DP63_RS25725	COG1070	Carbohydrate kinase
DP63_RS25730	COG1063	alcohol dehydrogenase
DP63_RS25735	COG1172	Belongs to the binding-protein-dependent transport system permease family
DP63_RS25745	COG1879	ABC-type sugar transport system periplasmic component
DP63_RS25765	COG2375	cellular response to nickel ion
DP63_RS25765	COG1132	(ABC) transporter
DP63_RS25775	COG3121	Chaperone
DP63_RS25785	COG3539	Fimbrial protein
DP63_RS25800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP63_RS25810	COG1309	transcriptional regulator
DP63_RS25815	COG0739	heme binding
DP63_RS25820	COG0765	amino acid transport
DP63_RS25825	COG4597	amino acid ABC transporter
DP63_RS25835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP63_RS25880	COG4964	Belongs to the GSP D family
DP63_RS25900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DP63_RS25905	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DP63_RS25915	COG0477	Major facilitator Superfamily
DP63_RS25920	COG2719	SpoVR family
DP63_RS25925	COG2718	Belongs to the UPF0229 family
DP63_RS25930	COG2766	serine protein kinase
DP63_RS25935	COG0840	transmembrane signaling receptor activity
DP63_RS25940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DP63_RS25945	COG1609	Transcriptional regulator
DP63_RS25950	COG1172	Belongs to the binding-protein-dependent transport system permease family
DP63_RS25955	COG1129	ABC transporter
DP63_RS25960	COG1879	ABC-type sugar transport system periplasmic component
DP63_RS25965	COG0583	DNA-binding transcription factor activity
DP63_RS25970	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DP63_RS25975	COG4208	sulfate ABC transporter
DP63_RS25980	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DP63_RS25985	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DP63_RS26025	COG0701	Predicted permease
DP63_RS26030	COG0667	Aldo Keto reductase
DP63_RS26055	COG1301	dicarboxylic acid transport
DP63_RS26085	COG1116	anion transmembrane transporter activity
DP63_RS26090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DP63_RS26145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP63_RS26150	COG0765	amino acid transport
DP63_RS26155	COG0673	inositol 2-dehydrogenase activity
DP63_RS26160	COG1802	Transcriptional regulator
DP63_RS26170	COG3023	N-Acetylmuramoyl-L-alanine amidase
DP63_RS26180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DP63_RS26185	COG0557	exoribonuclease II activity
DP63_RS26200	COG0840	transmembrane signaling receptor activity
DP63_RS26225	COG0519	Catalyzes the synthesis of GMP from XMP
DP63_RS26230	COG2814	Major facilitator Superfamily
DP63_RS26240	COG0318	PFAM AMP-dependent synthetase and ligase
DP63_RS26305	COG4964	Belongs to the GSP D family
DP63_RS26360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DP63_RS26365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DP63_RS26370	COG0508	dehydrogenase complex catalyzes the overall conversion of
DP63_RS26375	COG0567	Dehydrogenase, E1 component
DP63_RS26380	COG1217	gtp-binding protein TYPA
DP63_RS26385	COG1846	Transcriptional regulator
DP63_RS26395	COG1566	PFAM secretion protein HlyD family protein
DP63_RS26400	COG2814	Major facilitator Superfamily
DP63_RS26405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DP63_RS26420	COG2251	uridine kinase activity
DP63_RS26420	COG0195	Participates in both transcription termination and antitermination
DP63_RS26430	COG1187	pseudouridine synthase activity
DP63_RS26435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DP63_RS26440	COG0583	DNA-binding transcription factor activity
DP63_RS26485	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DP63_RS26505	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DP63_RS26505	COG2755	lipolytic protein G-D-S-L family
DP63_RS26520	COG0776	regulation of translation
DP63_RS26545	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DP63_RS26560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DP63_RS26565	COG0251	oxidation-reduction process
DP63_RS26570	COG2267	carboxylic ester hydrolase activity
DP63_RS26585	COG0583	DNA-binding transcription factor activity
DP63_RS26600	COG1028	Short-chain dehydrogenase reductase Sdr
DP63_RS26635	COG1028	Short-chain dehydrogenase reductase Sdr
DP63_RS26660	COG0477	Major facilitator Superfamily
DP63_RS26675	COG1295	ribonuclease BN
DP63_RS26690	COG0277	FAD linked oxidase domain protein
DP63_RS26705	COG0583	DNA-binding transcription factor activity
DP63_RS26735	COG0840	transmembrane signaling receptor activity
DP63_RS26740	COG2223	nitrite transmembrane transporter activity
DP63_RS26745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DP63_RS26750	COG0210	DNA helicase
DP63_RS26755	COG0525	valine-tRNA ligase activity
DP63_RS26760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DP63_RS26770	COG5002	protein histidine kinase activity
DP63_RS26780	COG0745	RESPONSE REGULATOR receiver
DP63_RS26790	COG0425	Belongs to the sulfur carrier protein TusA family
DP63_RS26795	COG0673	inositol 2-dehydrogenase activity
DP63_RS26800	COG0673	inositol 2-dehydrogenase activity
DP63_RS26815	COG1172	Belongs to the binding-protein-dependent transport system permease family
DP63_RS26830	COG3962	Belongs to the TPP enzyme family
DP63_RS26840	COG3718	enzyme involved in inositol metabolism
DP63_RS26850	COG0411	ABC transporter
DP63_RS26860	COG0824	Thioesterase
DP63_RS26875	COG2816	NAD+ diphosphatase activity
DP63_RS26885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP63_RS26890	COG0477	Major facilitator Superfamily
DP63_RS26905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DP63_RS26915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DP63_RS26920	COG1051	belongs to the nudix hydrolase family
DP63_RS26940	COG1858	cytochrome C peroxidase
DP63_RS26945	COG3511	phospholipase C
DP63_RS26955	COG1566	PFAM secretion protein HlyD family protein
DP63_RS26960	COG2814	Major facilitator Superfamily
DP63_RS26965	COG1538	Outer membrane efflux protein
DP63_RS26970	COG2197	response regulator
DP63_RS27010	COG0583	DNA-binding transcription factor activity
DP63_RS27015	COG2814	Major facilitator Superfamily
DP63_RS27185	COG0457	Tetratricopeptide repeat
DP63_RS27185	COG0859	PFAM glycosyl transferase family 9
DP63_RS27235	COG0745	RESPONSE REGULATOR receiver
DP63_RS27240	COG0583	DNA-binding transcription factor activity
DP63_RS27275	COG0366	Alpha amylase catalytic
DP63_RS27280	COG0366	Alpha amylase catalytic
DP63_RS27360	COG0582	viral genome integration into host DNA
DP63_RS27385	COG4942	peptidase
DP63_RS27390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DP63_RS27400	COG0534	Mate efflux family protein
DP63_RS27575	COG4626	Terminase
DP63_RS27575	COG1802	Transcriptional regulator
DP63_RS27695	COG0583	DNA-binding transcription factor activity
DP63_RS27825	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DP63_RS27835	COG0745	RESPONSE REGULATOR receiver
DP63_RS27850	COG0581	inorganic phosphate transmembrane transporter activity
DP63_RS27855	COG0573	inorganic phosphate transmembrane transporter activity
DP63_RS27860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DP63_RS27870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DP63_RS27875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DP63_RS27885	COG1534	Rna-binding protein
DP63_RS27895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DP63_RS27900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DP63_RS27910	COG0505	Belongs to the CarA family
DP63_RS27930	COG1388	LysM domain
DP63_RS27930	COG0741	lytic transglycosylase activity
DP63_RS27935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DP63_RS27940	COG2226	methyltransferase
DP63_RS27945	COG0328	RNA-DNA hybrid ribonuclease activity
DP63_RS27950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DP63_RS27960	COG0477	Major facilitator Superfamily
DP63_RS27990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DP63_RS28000	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DP63_RS28020	COG3052	prosthetic group binding
DP63_RS28045	COG0583	DNA-binding transcription factor activity
DP63_RS28050	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP63_RS28055	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DP63_RS28090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DP63_RS28125	COG0583	DNA-binding transcription factor activity
DP63_RS28145	COG1522	sequence-specific DNA binding
DP63_RS28190	COG1609	Transcriptional regulator
DP63_RS28200	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DP63_RS28215	COG1177	transmembrane transport
DP63_RS28220	COG3842	ATPase activity
DP63_RS28225	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DP63_RS28245	COG2814	Major facilitator Superfamily
DP63_RS28250	COG0697	spore germination
DP63_RS28260	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DP63_RS28265	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
DP63_RS28305	COG2200	EAL domain
DP63_RS28315	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DP63_RS28320	COG1074	ATP-dependent DNA helicase activity
DP63_RS28325	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DP63_RS28340	COG1289	transmembrane transporter activity
DP63_RS28355	COG1840	ABC-type Fe3 transport system, periplasmic component
DP63_RS28360	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP63_RS28365	COG3842	ATPase activity
DP63_RS28370	COG1522	sequence-specific DNA binding
DP63_RS28385	COG1959	2 iron, 2 sulfur cluster binding
DP63_RS28415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP63_RS28420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP63_RS28455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DP63_RS28470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DP63_RS28470	COG2010	Cytochrome c
DP63_RS28475	COG2863	cytochrome
DP63_RS28495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DP63_RS28505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DP63_RS28520	COG0006	proline dipeptidase activity
DP63_RS28525	COG2801	Transposase and inactivated derivatives
DP63_RS28530	COG2963	transposase activity
DP63_RS28580	COG2866	Carboxypeptidase
DP63_RS28595	COG0436	Aminotransferase
DP63_RS28605	COG1024	Enoyl-CoA hydratase
DP63_RS28610	COG0588	phosphoglycerate mutase activity
DP63_RS28620	COG1960	acyl-CoA dehydrogenase activity
DP63_RS28640	COG1012	belongs to the aldehyde dehydrogenase family
DP63_RS28640	COG2030	dehydratase
DP63_RS28645	COG1960	acyl-CoA dehydrogenase activity
DP63_RS28650	COG1960	acyl-CoA dehydrogenase activity
DP63_RS28670	COG1007	ATP synthesis coupled electron transport
DP63_RS28705	COG1034	ATP synthesis coupled electron transport
DP63_RS28715	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DP63_RS28750	COG0149	triose-phosphate isomerase activity
DP63_RS28755	COG3321	synthase
DP63_RS28755	COG4221	oxidoreductase activity
DP63_RS28755	COG0604	alcohol dehydrogenase
DP63_RS28755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DP63_RS28770	COG0683	leucine binding
DP63_RS28780	COG0288	reversible hydration of carbon dioxide
DP63_RS28785	COG0659	secondary active sulfate transmembrane transporter activity
DP63_RS28795	COG1183	phosphatidylcholine synthase activity
DP63_RS28815	COG0028	Belongs to the TPP enzyme family
DP63_RS28845	COG0438	transferase activity, transferring glycosyl groups
DP63_RS28865	COG1028	Short-chain dehydrogenase reductase Sdr
DP63_RS28870	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DP63_RS28880	COG0154	amidase activity
DP63_RS28890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DP63_RS28920	COG0745	RESPONSE REGULATOR receiver
DP63_RS28925	COG2205	protein histidine kinase activity
DP63_RS28940	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DP63_RS28945	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DP63_RS28965	COG1028	Short-chain dehydrogenase reductase Sdr
DP63_RS28980	COG0151	Belongs to the GarS family
DP63_RS28995	COG0799	negative regulation of ribosome biogenesis
DP63_RS29015	COG2233	PERMEase
DP63_RS29055	COG1595	DNA-templated transcription, initiation
DP63_RS29060	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DP63_RS29090	COG0859	PFAM glycosyl transferase family 9
DP63_RS29095	COG0438	transferase activity, transferring glycosyl groups
DP63_RS29135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DP63_RS29140	COG0513	Belongs to the DEAD box helicase family
DP63_RS29170	COG1674	ftsk spoiiie
DP63_RS29175	COG2706	6-phosphogluconolactonase activity
DP63_RS29180	COG3387	PFAM Glycoside hydrolase 15-related
DP63_RS29190	COG1309	transcriptional regulator
DP63_RS29195	COG2878	Part of a membrane complex involved in electron transport
DP63_RS29200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DP63_RS29235	COG3135	benzoate transporter
DP63_RS29250	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DP63_RS29265	COG4106	trans-aconitate 2-methyltransferase activity
DP63_RS29285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DP63_RS29295	COG0697	spore germination
DP63_RS29300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DP63_RS29340	COG0477	Major facilitator Superfamily
DP63_RS29345	COG0583	DNA-binding transcription factor activity
DP63_RS29355	COG0583	DNA-binding transcription factor activity
DP63_RS29380	COG0488	(ABC) transporter
DP63_RS29390	COG1773	rubredoxin
DP63_RS29435	COG0582	viral genome integration into host DNA
DP63_RS29515	COG4626	Terminase
DP63_RS29515	COG1802	Transcriptional regulator
DP63_RS29590	COG1881	PFAM PEBP family protein
DP63_RS29595	COG2814	Major facilitator Superfamily
DP63_RS29610	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DP63_RS29630	COG1116	anion transmembrane transporter activity
DP63_RS29635	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP63_RS29660	COG1741	Belongs to the pirin family
DP63_RS29675	COG4215	(ABC) transporter
DP63_RS29695	COG0347	Belongs to the P(II) protein family
DP63_RS29710	COG1472	Belongs to the glycosyl hydrolase 3 family
DP63_RS29715	COG2827	Endonuclease containing a URI domain
DP63_RS29720	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DP63_RS29735	COG2271	Major facilitator Superfamily
DP63_RS29765	COG2226	methyltransferase
DP63_RS29800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DP63_RS29825	COG0489	protein tyrosine kinase activity
DP63_RS29830	COG2885	chlorophyll binding
DP63_RS29830	COG3047	cAMP biosynthetic process
DP63_RS29850	COG2911	Protein conserved in bacteria
DP63_RS29855	COG0729	surface antigen
DP63_RS29865	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DP63_RS29880	COG0489	protein tyrosine kinase activity
DP63_RS29885	COG2259	Doxx family
DP63_RS29890	COG1492	cobalamin metabolic process
DP63_RS29900	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DP63_RS29910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DP63_RS29925	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DP63_RS29930	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DP63_RS29935	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DP63_RS29945	COG4206	TonB-dependent receptor
DP63_RS29975	COG0583	DNA-binding transcription factor activity
DP63_RS29985	COG4654	Cytochrome c, class I
DP63_RS30005	COG0795	lipopolysaccharide-transporting ATPase activity
DP63_RS30020	COG1648	precorrin-2 dehydrogenase activity
DP63_RS30020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DP63_RS30025	COG2895	sulfate adenylyltransferase (ATP) activity
DP63_RS30035	COG0175	sulfate reduction
DP63_RS30050	COG0583	DNA-binding transcription factor activity
DP63_RS30060	COG0582	viral genome integration into host DNA
DP63_RS30105	COG4133	protoheme IX ABC transporter activity
DP63_RS30120	COG1396	sequence-specific DNA binding
DP63_RS30130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DP63_RS30135	COG2258	MOSC domain
DP63_RS30140	COG2267	carboxylic ester hydrolase activity
DP63_RS30150	COG0583	DNA-binding transcription factor activity
DP63_RS30160	COG1187	pseudouridine synthase activity
DP63_RS30175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DP63_RS30175	COG0543	2 iron, 2 sulfur cluster binding
DP63_RS30180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DP63_RS30185	COG0456	acetyltransferase
DP63_RS30220	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DP63_RS30225	COG1047	Peptidyl-prolyl cis-trans
DP63_RS30245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DP63_RS30265	COG1511	domain protein
DP63_RS30265	COG3264	Mechanosensitive ion channel
DP63_RS30270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DP63_RS30270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DP63_RS30275	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DP63_RS30280	COG0196	riboflavin kinase activity
DP63_RS30285	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DP63_RS30315	COG1113	amino acid transport
DP63_RS30320	COG0542	response to heat
DP63_RS30330	COG1278	Cold shock
DP63_RS30335	COG2132	Multicopper oxidase
DP63_RS30355	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DP63_RS30375	COG0656	L-ascorbic acid biosynthetic process
DP63_RS30380	COG2188	Transcriptional regulator
DP63_RS30400	COG2814	Major facilitator Superfamily
DP63_RS30415	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DP63_RS30445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DP63_RS30450	COG1570	exodeoxyribonuclease VII activity
DP63_RS30455	COG1663	tetraacyldisaccharide 4'-kinase activity
DP63_RS30485	COG0728	peptidoglycan biosynthetic process
DP63_RS30500	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DP63_RS30520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DP63_RS30525	COG0318	PFAM AMP-dependent synthetase and ligase
DP63_RS30530	COG4974	Belongs to the 'phage' integrase family
DP63_RS30540	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DP63_RS30545	COG0802	atpase or kinase
DP63_RS30550	COG0860	N-Acetylmuramoyl-L-alanine amidase
DP63_RS30560	COG1741	Belongs to the pirin family
DP63_RS30565	COG3118	belongs to the thioredoxin family
DP63_RS30575	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DP63_RS30585	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DP63_RS30600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DP63_RS30610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DP63_RS30615	COG1522	sequence-specific DNA binding
DP63_RS30635	COG2271	Major facilitator Superfamily
DP63_RS30645	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DP63_RS30650	COG1012	belongs to the aldehyde dehydrogenase family
DP63_RS30660	COG0583	DNA-binding transcription factor activity
DP63_RS30665	COG0246	Mannitol dehydrogenase
DP63_RS30670	COG1070	Carbohydrate kinase
DP63_RS30675	COG2390	Transcriptional regulator
DP63_RS30690	COG0583	DNA-binding transcription factor activity
DP63_RS30700	COG3842	ATPase activity
DP63_RS30705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DP63_RS30715	COG1175	transmembrane transport
DP63_RS30730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DP63_RS30740	COG0735	belongs to the Fur family
DP63_RS30750	COG1121	(ABC) transporter
DP63_RS30755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DP63_RS30760	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DP63_RS30775	COG1070	Carbohydrate kinase
DP63_RS30780	COG2233	PERMEase
DP63_RS30790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP63_RS30795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DP63_RS30820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP63_RS30850	COG0009	L-threonylcarbamoyladenylate synthase
DP63_RS30855	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DP63_RS30860	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DP63_RS30865	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DP63_RS30875	COG0469	pyruvate kinase activity
DP63_RS30880	COG0126	phosphoglycerate kinase activity
DP63_RS30905	COG0859	PFAM glycosyl transferase family 9
DP63_RS30915	COG0429	hydrolase of the alpha beta-hydrolase fold
DP63_RS30925	COG4783	chaperone-mediated protein folding
DP63_RS30945	COG3307	-O-antigen
DP63_RS30950	COG4969	Belongs to the N-Me-Phe pilin family
DP63_RS30955	COG0861	Integral membrane protein TerC family
DP63_RS30960	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DP63_RS30975	COG2137	regulation of response to DNA damage stimulus
DP63_RS30980	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DP63_RS31025	COG0784	Response regulator, receiver
DP63_RS31025	COG5002	protein histidine kinase activity
DP63_RS31030	COG0583	DNA-binding transcription factor activity
DP63_RS31070	COG0028	Belongs to the TPP enzyme family
DP63_RS31075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DP63_RS31080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DP63_RS31155	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DP63_RS31180	COG0840	transmembrane signaling receptor activity
DP63_RS31220	COG4948	Mandelate Racemase Muconate Lactonizing
DP63_RS31240	COG0513	Belongs to the DEAD box helicase family
DP63_RS31280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DP63_RS31285	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DP63_RS31295	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DP63_RS31300	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DP63_RS31305	COG0367	asparagine synthase
DP63_RS31320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DP63_RS31330	COG1396	sequence-specific DNA binding
DP63_RS31335	COG2814	Major facilitator Superfamily
DP63_RS31340	COG0583	DNA-binding transcription factor activity
DP63_RS31350	COG1702	phosphate starvation-inducible protein PhoH
DP63_RS31360	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DP63_RS31370	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DP63_RS31375	COG0752	glycyl-tRNA synthetase alpha subunit
DP63_RS31380	COG0751	glycine-tRNA ligase activity
DP63_RS31385	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DP63_RS31390	COG0204	Acyl-transferase
DP63_RS31515	COG4974	Belongs to the 'phage' integrase family