locus-tag	class	description
DP47_RS00515	COG3639	organic phosphonate transmembrane transporter activity
DP47_RS00995	COG1172	Belongs to the binding-protein-dependent transport system permease family
DP47_RS01050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DP47_RS01475	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DP47_RS03050	COG1960	acyl-CoA dehydrogenase activity
DP47_RS03525	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP47_RS03875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DP47_RS04235	COG2814	Major facilitator Superfamily
DP47_RS04650	COG1706	bacterial-type flagellum-dependent cell motility
DP47_RS05050	COG0025	NhaP-type Na H and K H
DP47_RS05060	COG2200	EAL domain
DP47_RS05060	COG2199	diguanylate cyclase activity
DP47_RS05300	COG2226	methyltransferase
DP47_RS05910	COG3829	transcription factor binding
DP47_RS05910	COG3290	protein histidine kinase activity
DP47_RS06175	COG0513	Belongs to the DEAD box helicase family
DP47_RS06680	COG0246	Mannitol dehydrogenase
DP47_RS06770	COG3118	belongs to the thioredoxin family
DP47_RS06775	COG1741	Belongs to the pirin family
DP47_RS06865	COG1570	exodeoxyribonuclease VII activity
DP47_RS07305	COG1492	cobalamin metabolic process
DP47_RS07535	COG1741	Belongs to the pirin family
DP47_RS07855	COG0187	DNA topoisomerase II activity
DP47_RS07880	COG0477	Major facilitator Superfamily
DP47_RS07995	COG3135	benzoate transporter
DP47_RS08180	COG0438	transferase activity, transferring glycosyl groups
DP47_RS08240	COG2233	PERMEase
DP47_RS08415	COG0028	Belongs to the TPP enzyme family
DP47_RS08465	COG0659	secondary active sulfate transmembrane transporter activity
DP47_RS08470	COG0288	reversible hydration of carbon dioxide
DP47_RS08640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP47_RS08955	COG0583	DNA-binding transcription factor activity
DP47_RS09000	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DP47_RS09170	COG0573	inorganic phosphate transmembrane transporter activity
DP47_RS09380	COG0366	Alpha amylase catalytic
DP47_RS09385	COG0366	Alpha amylase catalytic
DP47_RS09470	COG5295	Hep Hag repeat protein
DP47_RS09480	COG0859	PFAM glycosyl transferase family 9
DP47_RS09480	COG0457	Tetratricopeptide repeat
DP47_RS09845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DP47_RS10025	COG0210	DNA helicase
DP47_RS10215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DP47_RS10415	COG0567	Dehydrogenase, E1 component
DP47_RS10420	COG0567	Dehydrogenase, E1 component
DP47_RS10810	COG2719	SpoVR family
DP47_RS10960	COG1063	alcohol dehydrogenase
DP47_RS11005	COG4615	Cyclic peptide transporter
DP47_RS11070	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DP47_RS11165	COG3209	COG3209 Rhs family protein
DP47_RS11305	COG2235	arginine
DP47_RS11505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DP47_RS11530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DP47_RS11990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DP47_RS12075	COG3188	usher protein
DP47_RS12140	COG2376	Dihydroxyacetone kinase
DP47_RS12365	COG3842	ATPase activity
DP47_RS12500	COG3243	poly(R)-hydroxyalkanoic acid synthase
DP47_RS12530	COG1199	ATP-dependent helicase activity
DP47_RS12535	COG1199	ATP-dependent helicase activity
DP47_RS12700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DP47_RS12705	COG0778	Nitroreductase
DP47_RS12710	COG2814	Major facilitator Superfamily
DP47_RS12735	COG2814	Major facilitator Superfamily
DP47_RS12745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DP47_RS12770	COG1960	acyl-CoA dehydrogenase activity
DP47_RS12780	COG0450	alkyl hydroperoxide reductase
DP47_RS12835	COG4221	oxidoreductase activity
DP47_RS12840	COG0824	Thioesterase
DP47_RS12865	COG2885	chlorophyll binding
DP47_RS12900	COG0517	IMP dehydrogenase activity
DP47_RS12900	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DP47_RS12905	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DP47_RS12910	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DP47_RS12925	COG1045	serine acetyltransferase
DP47_RS12930	COG3562	capsule polysaccharide
DP47_RS12940	COG0489	protein tyrosine kinase activity
DP47_RS12940	COG3206	protein involved in exopolysaccharide biosynthesis
DP47_RS12945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DP47_RS12990	COG0156	8-amino-7-oxononanoate synthase activity
DP47_RS12995	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DP47_RS13000	COG3321	synthase
DP47_RS13000	COG1028	Short-chain dehydrogenase reductase Sdr
DP47_RS13000	COG0604	alcohol dehydrogenase
DP47_RS13005	COG1368	sulfuric ester hydrolase activity
DP47_RS13020	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DP47_RS13120	COG0586	Pfam SNARE associated Golgi protein
DP47_RS13125	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DP47_RS13145	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DP47_RS13155	COG0617	tRNA 3'-terminal CCA addition
DP47_RS13160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DP47_RS13165	COG1428	Deoxynucleoside kinase
DP47_RS13175	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DP47_RS13215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DP47_RS13220	COG0497	DNA recombination
DP47_RS13225	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DP47_RS13230	COG3164	Protein of unknown function
DP47_RS13235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DP47_RS13240	COG0312	modulator of DNA gyrase
DP47_RS13245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DP47_RS13255	COG1017	nitric oxide dioxygenase activity
DP47_RS13255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DP47_RS13260	COG2096	Adenosyltransferase
DP47_RS13265	COG0277	FAD linked oxidase domain protein
DP47_RS13270	COG0277	FAD linked oxidase domain protein
DP47_RS13275	COG0277	FAD linked oxidase domain protein
DP47_RS13280	COG0247	lactate metabolic process
DP47_RS13295	COG3639	organic phosphonate transmembrane transporter activity
DP47_RS13300	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DP47_RS13310	COG3454	Phosphonate metabolism
DP47_RS13315	COG4778	phosphonate C-P lyase system protein PhnL
DP47_RS13320	COG4107	phosphonate C-P lyase system protein PhnK
DP47_RS13325	COG3627	carbon phosphorus lyase activity
DP47_RS13330	COG3626	phosphonate metabolism
DP47_RS13340	COG3624	Phosphonate C-P lyase system protein PhnG
DP47_RS13345	COG2188	Transcriptional regulator
DP47_RS13350	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DP47_RS13355	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DP47_RS13375	COG0783	Belongs to the Dps family
DP47_RS13395	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DP47_RS13405	COG0343	queuine tRNA-ribosyltransferase activity
DP47_RS13410	COG1862	Preprotein translocase
DP47_RS13415	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DP47_RS13420	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DP47_RS13430	COG2353	YceI-like domain
DP47_RS13435	COG2353	YceI-like domain
DP47_RS13450	COG2995	paraquat-inducible protein a
DP47_RS13455	COG3008	intermembrane lipid transfer
DP47_RS13455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DP47_RS13525	COG0069	glutamate synthase activity
DP47_RS13530	COG0625	glutathione transferase activity
DP47_RS13535	COG0006	proline dipeptidase activity
DP47_RS13540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DP47_RS13545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DP47_RS13550	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DP47_RS13585	COG0588	phosphoglycerate mutase activity
DP47_RS13605	COG0625	glutathione transferase activity
DP47_RS13610	COG0625	glutathione transferase activity
DP47_RS13615	COG1917	Cupin 2, conserved barrel domain protein
DP47_RS13615	COG4977	sequence-specific DNA binding
DP47_RS13645	COG0418	dihydroorotase activity
DP47_RS13650	COG0121	glutamine amidotransferase
DP47_RS13680	COG1126	abc transporter atp-binding protein
DP47_RS13685	COG0765	amino acid transport
DP47_RS13690	COG0765	amino acid transport
DP47_RS13695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP47_RS13700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DP47_RS13705	COG0583	DNA-binding transcription factor activity
DP47_RS13710	COG2223	nitrite transmembrane transporter activity
DP47_RS13730	COG0800	Aldolase
DP47_RS13740	COG1737	Transcriptional regulator
DP47_RS13740	COG0837	glucose binding
DP47_RS13750	COG1981	membrane
DP47_RS13760	COG1466	dna polymerase III delta subunit
DP47_RS13790	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DP47_RS13795	COG0735	belongs to the Fur family
DP47_RS13800	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DP47_RS13805	COG4266	Belongs to the allantoicase family
DP47_RS13810	COG1301	dicarboxylic acid transport
DP47_RS13820	COG0583	DNA-binding transcription factor activity
DP47_RS13835	COG2814	Major facilitator Superfamily
DP47_RS13840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DP47_RS13845	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DP47_RS13850	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DP47_RS13860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DP47_RS13885	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DP47_RS13890	COG1546	Belongs to the CinA family
DP47_RS13895	COG0284	orotidine-5'-phosphate decarboxylase activity
DP47_RS13905	COG1028	Short-chain dehydrogenase reductase Sdr
DP47_RS13910	COG1172	Belongs to the binding-protein-dependent transport system permease family
DP47_RS13925	COG1028	Short-chain dehydrogenase reductase Sdr
DP47_RS13935	COG3734	2-keto-3-deoxy-galactonokinase
DP47_RS13940	COG1414	Transcriptional regulator
DP47_RS13955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DP47_RS13960	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DP47_RS13965	COG0557	exoribonuclease II activity
DP47_RS13970	COG3150	esterase
DP47_RS13975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DP47_RS13985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DP47_RS13990	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DP47_RS13995	COG0511	ligase activity, forming carbon-carbon bonds
DP47_RS14000	COG0439	Biotin carboxylase
DP47_RS14005	COG2264	protein methyltransferase activity
DP47_RS14015	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DP47_RS14020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DP47_RS14060	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DP47_RS14065	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DP47_RS14070	COG2095	MarC family integral membrane protein
DP47_RS14110	COG0142	geranyltranstransferase activity
DP47_RS14120	COG4536	flavin adenine dinucleotide binding
DP47_RS14125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DP47_RS14135	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DP47_RS14150	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DP47_RS14155	COG0494	nUDIX hydrolase
DP47_RS14185	COG0678	peroxiredoxin activity
DP47_RS14200	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DP47_RS14235	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DP47_RS14240	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DP47_RS14250	COG3116	cell division
DP47_RS14270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP47_RS14275	COG0318	PFAM AMP-dependent synthetase and ligase
DP47_RS14280	COG0243	molybdopterin cofactor binding
DP47_RS14310	COG1024	Enoyl-CoA hydratase
DP47_RS14320	COG0183	Belongs to the thiolase family
DP47_RS14325	COG1024	Enoyl-CoA hydratase
DP47_RS14330	COG2050	protein possibly involved in aromatic compounds catabolism
DP47_RS14340	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DP47_RS14350	COG2967	ApaG domain
DP47_RS14355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DP47_RS14360	COG0546	phosphoglycolate phosphatase activity
DP47_RS14370	COG0512	Glutamine amidotransferase of anthranilate synthase
DP47_RS14390	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DP47_RS14405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DP47_RS14410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DP47_RS14425	COG0012	GTP binding
DP47_RS14455	COG0584	glycerophosphoryl diester phosphodiesterase
DP47_RS14470	COG0488	(ABC) transporter
DP47_RS14480	COG1335	isochorismatase
DP47_RS14490	COG0006	proline dipeptidase activity
DP47_RS14520	COG2890	protein-(glutamine-N5) methyltransferase activity
DP47_RS14525	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DP47_RS14535	COG3384	dioxygenase
DP47_RS14540	COG0531	amino acid
DP47_RS14545	COG1278	Cold shock
DP47_RS14550	COG0443	Heat shock 70 kDa protein
DP47_RS14600	COG0308	aminopeptidase N
DP47_RS14745	COG1196	nuclear chromosome segregation
DP47_RS14750	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DP47_RS14765	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DP47_RS14785	COG5377	YqaJ viral recombinase family
DP47_RS14830	COG0582	viral genome integration into host DNA
DP47_RS14840	COG2969	positive regulation of protein catabolic process
DP47_RS14845	COG0625	glutathione transferase activity
DP47_RS14850	COG2857	Cytochrome c1
DP47_RS14855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DP47_RS14860	COG0723	plastoquinol--plastocyanin reductase activity
DP47_RS14865	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DP47_RS14870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP47_RS14880	COG0805	protein transport
DP47_RS14930	COG2095	MarC family integral membrane protein
DP47_RS14940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DP47_RS14945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DP47_RS14965	COG0842	Transport permease protein
DP47_RS14970	COG1131	(ABC) transporter
DP47_RS14990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DP47_RS14995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DP47_RS15000	COG1127	ABC transporter
DP47_RS15025	COG4178	(ABC) transporter
DP47_RS15035	COG1115	amino acid carrier protein
DP47_RS15045	COG0069	glutamate synthase activity
DP47_RS15045	COG0070	glutamate synthase
DP47_RS15045	COG0067	glutamate synthase
DP47_RS15060	COG0584	glycerophosphoryl diester phosphodiesterase
DP47_RS15065	COG3842	ATPase activity
DP47_RS15070	COG0395	ABC-type sugar transport system, permease component
DP47_RS15075	COG1175	transmembrane transport
DP47_RS15085	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DP47_RS15140	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DP47_RS15145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DP47_RS15150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DP47_RS15155	COG1333	cytochrome c biogenesis protein
DP47_RS15175	COG4232	protein-disulfide reductase activity
DP47_RS15220	COG0201	protein transport
DP47_RS15350	COG0514	ATP-dependent DNA helicase (RecQ)
DP47_RS15395	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DP47_RS15430	COG2801	Transposase and inactivated derivatives
DP47_RS15465	COG3396	Phenylacetate-CoA oxygenase
DP47_RS15470	COG3460	Phenylacetate-CoA oxygenase
DP47_RS15475	COG3396	Phenylacetate-CoA oxygenase
DP47_RS15480	COG2151	metal-sulfur cluster biosynthetic enzyme
DP47_RS15485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DP47_RS15505	COG1522	sequence-specific DNA binding
DP47_RS15525	COG0281	malic enzyme
DP47_RS15525	COG0280	phosphate acetyltransferase
DP47_RS15530	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DP47_RS15535	COG1881	PFAM PEBP family protein
DP47_RS15545	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DP47_RS15560	COG3047	cAMP biosynthetic process
DP47_RS15565	COG0583	DNA-binding transcription factor activity
DP47_RS15570	COG2814	Major facilitator Superfamily
DP47_RS15575	COG1280	lysine exporter protein (LysE YggA)
DP47_RS15580	COG2084	Dehydrogenase
DP47_RS15610	COG1113	amino acid transport
DP47_RS15625	COG2823	Periplasmic or secreted lipoprotein
DP47_RS15630	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DP47_RS15650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DP47_RS15660	COG1522	sequence-specific DNA binding
DP47_RS15665	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DP47_RS15690	COG2070	2-Nitropropane dioxygenase
DP47_RS15705	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DP47_RS15710	COG1950	PFAM Membrane protein of
DP47_RS15735	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DP47_RS15740	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DP47_RS15760	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DP47_RS15765	COG0745	RESPONSE REGULATOR receiver
DP47_RS15770	COG2201	protein-glutamate methylesterase activity
DP47_RS15780	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DP47_RS15800	COG2201	protein-glutamate methylesterase activity
DP47_RS15805	COG1360	Flagellar Motor Protein
DP47_RS15825	COG0438	transferase activity, transferring glycosyl groups
DP47_RS15835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DP47_RS15840	COG0561	phosphatase activity
DP47_RS15850	COG0519	Catalyzes the synthesis of GMP from XMP
DP47_RS15885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DP47_RS15900	COG1028	Short-chain dehydrogenase reductase Sdr
DP47_RS15955	COG2267	carboxylic ester hydrolase activity
DP47_RS15975	COG3397	chitin binding
DP47_RS16000	COG0582	viral genome integration into host DNA
DP47_RS16055	COG1205	dead DEAH box helicase
DP47_RS16055	COG1111	helicase
DP47_RS16065	COG5377	YqaJ viral recombinase family
DP47_RS16140	COG3245	cytochrome
DP47_RS16145	COG0210	DNA helicase
DP47_RS16160	COG0673	inositol 2-dehydrogenase activity
DP47_RS16175	COG0509	glycine decarboxylation via glycine cleavage system
DP47_RS16190	COG1760	l-serine dehydratase
DP47_RS16215	COG1012	belongs to the aldehyde dehydrogenase family
DP47_RS16225	COG4302	ethanolamine ammonia-lyase activity
DP47_RS16230	COG4303	Ethanolamine ammonia lyase large subunit
DP47_RS16235	COG0531	amino acid
DP47_RS16250	COG0668	transmembrane transport
DP47_RS16270	COG0789	Transcriptional regulator
DP47_RS16280	COG0277	FAD linked oxidase domain protein
DP47_RS16295	COG0436	Aminotransferase
DP47_RS16305	COG1960	acyl-CoA dehydrogenase activity
DP47_RS16320	COG0506	proline dehydrogenase activity
DP47_RS16320	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DP47_RS16320	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DP47_RS16330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DP47_RS16345	COG1832	CoA-binding protein
DP47_RS16350	COG0318	PFAM AMP-dependent synthetase and ligase
DP47_RS16390	COG0356	it plays a direct role in the translocation of protons across the membrane
DP47_RS16400	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DP47_RS16405	COG1475	DNA binding
DP47_RS16410	COG1192	Involved in chromosome partitioning
DP47_RS16455	COG0559	Belongs to the binding-protein-dependent transport system permease family
DP47_RS16475	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DP47_RS16485	COG0583	DNA-binding transcription factor activity
DP47_RS16495	COG1522	sequence-specific DNA binding
DP47_RS16500	COG3186	Phenylalanine-4-hydroxylase
DP47_RS16520	COG0642	Histidine kinase
DP47_RS16535	COG1902	pentaerythritol trinitrate reductase activity
DP47_RS16540	COG0519	Catalyzes the synthesis of GMP from XMP
DP47_RS16540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DP47_RS16570	COG0523	cobalamin synthesis protein
DP47_RS16590	COG1459	type II secretion system
DP47_RS16605	COG2165	general secretion pathway protein
DP47_RS16650	COG1846	Transcriptional regulator
DP47_RS16655	COG2814	Major facilitator Superfamily
DP47_RS16660	COG0583	DNA-binding transcription factor activity
DP47_RS16670	COG1346	cytolysis
DP47_RS16685	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DP47_RS16700	COG1987	bacterial-type flagellum assembly
DP47_RS16710	COG0789	Transcriptional regulator
DP47_RS16715	COG4106	trans-aconitate 2-methyltransferase activity
DP47_RS16715	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DP47_RS16725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DP47_RS16735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DP47_RS16750	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP47_RS16765	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP47_RS16825	COG1695	Transcriptional regulator
DP47_RS16850	COG1960	acyl-CoA dehydrogenase activity
DP47_RS16860	COG0183	Belongs to the thiolase family
DP47_RS16865	COG1024	Enoyl-CoA hydratase
DP47_RS16865	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP47_RS16870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DP47_RS16910	COG0753	catalase activity
DP47_RS16925	COG2963	transposase activity
DP47_RS16930	COG2801	Transposase and inactivated derivatives
DP47_RS16940	COG0592	DNA-directed DNA polymerase activity
DP47_RS16980	COG0582	viral genome integration into host DNA
DP47_RS17030	COG2801	Transposase and inactivated derivatives
DP47_RS17035	COG2963	transposase activity
DP47_RS17060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DP47_RS17080	COG2169	Transcriptional regulator
DP47_RS17080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DP47_RS17095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DP47_RS17110	COG0583	DNA-binding transcription factor activity
DP47_RS17125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DP47_RS17135	COG4695	Portal protein
DP47_RS17180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DP47_RS17185	COG0583	DNA-binding transcription factor activity
DP47_RS17200	COG0758	DNA mediated transformation
DP47_RS17205	COG0242	peptide deformylase activity
DP47_RS17225	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DP47_RS17225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DP47_RS17235	COG5000	phosphorelay sensor kinase activity
DP47_RS17240	COG2204	response regulator
DP47_RS17470	COG4695	Portal protein
DP47_RS17500	COG0602	queuosine metabolic process
DP47_RS17505	COG0720	synthase
DP47_RS17520	COG0772	Belongs to the SEDS family
DP47_RS17525	COG0768	penicillin binding
DP47_RS17540	COG1077	Cell shape determining protein MreB Mrl
DP47_RS17560	COG2326	polyphosphate kinase activity
DP47_RS17565	COG0708	Exodeoxyribonuclease III
DP47_RS17570	COG1064	alcohol dehydrogenase
DP47_RS17575	COG2207	Transcriptional regulator
DP47_RS17585	COG2814	Major facilitator Superfamily
DP47_RS17600	COG1309	transcriptional regulator
DP47_RS17625	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DP47_RS17645	COG0523	cobalamin synthesis protein
DP47_RS17655	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DP47_RS17670	COG1560	Kdo2-lipid A biosynthetic process
DP47_RS17695	COG0667	Aldo Keto reductase
DP47_RS17710	COG2814	Major facilitator Superfamily
DP47_RS17720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DP47_RS17735	COG1960	acyl-CoA dehydrogenase activity
DP47_RS17795	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DP47_RS17810	COG0531	amino acid
DP47_RS17830	COG1280	lysine exporter protein (LysE YggA)
DP47_RS17835	COG3568	Endonuclease Exonuclease Phosphatase
DP47_RS17855	COG0579	oxidoreductase
DP47_RS17870	COG0747	negative chemotaxis
DP47_RS17875	COG0601	transmembrane transport
DP47_RS17880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DP47_RS17885	COG0444	Belongs to the ABC transporter superfamily
DP47_RS17890	COG4608	Belongs to the ABC transporter superfamily
DP47_RS17920	COG1984	allophanate hydrolase subunit 2
DP47_RS17925	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DP47_RS17935	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DP47_RS17940	COG0741	lytic transglycosylase activity
DP47_RS17975	COG2747	anti-sigma28 factor FlgM
DP47_RS17985	COG1815	bacterial-type flagellum-dependent cell motility
DP47_RS17990	COG1558	bacterial-type flagellum-dependent cell motility
DP47_RS17995	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DP47_RS18000	COG1749	Flagellar hook protein flgE
DP47_RS18015	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DP47_RS18020	COG1706	bacterial-type flagellum-dependent cell motility
DP47_RS18030	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DP47_RS18040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DP47_RS18045	COG2233	PERMEase
DP47_RS18050	COG0583	DNA-binding transcription factor activity
DP47_RS18070	COG2824	Alkylphosphonate utilization operon protein PhnA
DP47_RS18080	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP47_RS18175	COG1704	LemA family
DP47_RS18180	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DP47_RS18200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DP47_RS18205	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP47_RS18225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DP47_RS18230	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DP47_RS18275	COG1609	Transcriptional regulator
DP47_RS18280	COG0840	transmembrane signaling receptor activity
DP47_RS18300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP47_RS18305	COG0583	DNA-binding transcription factor activity
DP47_RS18315	COG0596	Alpha beta hydrolase
DP47_RS18345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DP47_RS18365	COG3511	phospholipase C
DP47_RS18395	COG1999	signal sequence binding
DP47_RS18410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DP47_RS18440	COG2204	response regulator
DP47_RS18470	COG0025	NhaP-type Na H and K H
DP47_RS18475	COG2199	diguanylate cyclase activity
DP47_RS18475	COG2200	EAL domain
DP47_RS18485	COG1785	Belongs to the alkaline phosphatase family
DP47_RS18510	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DP47_RS18530	COG3012	SEC-C Motif Domain Protein
DP47_RS18540	COG0183	Belongs to the thiolase family
DP47_RS18545	COG0288	reversible hydration of carbon dioxide
DP47_RS18560	COG0488	(ABC) transporter
DP47_RS18565	COG0747	negative chemotaxis
DP47_RS18580	COG1028	Short-chain dehydrogenase reductase Sdr
DP47_RS18585	COG4221	oxidoreductase activity
DP47_RS18590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DP47_RS18640	COG1024	Enoyl-CoA hydratase
DP47_RS18660	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DP47_RS18670	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DP47_RS18685	COG0737	Belongs to the 5'-nucleotidase family
DP47_RS18690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DP47_RS18695	COG1127	ABC transporter
DP47_RS18730	COG1686	Belongs to the peptidase S11 family
DP47_RS18740	COG2921	Belongs to the UPF0250 family
DP47_RS18745	COG0583	DNA-binding transcription factor activity
DP47_RS18785	COG0583	DNA-binding transcription factor activity
DP47_RS18790	COG1024	Enoyl-CoA hydratase
DP47_RS18790	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP47_RS18795	COG1960	acyl-CoA dehydrogenase activity
DP47_RS18800	COG1960	acyl-CoA dehydrogenase activity
DP47_RS18805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DP47_RS18815	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DP47_RS18825	COG4191	Histidine kinase
DP47_RS18835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DP47_RS18865	COG2960	long-chain fatty acid transporting porin activity
DP47_RS18875	COG0004	ammonium transporteR
DP47_RS18885	COG0189	ligase activity
DP47_RS18895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP47_RS18900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DP47_RS18905	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DP47_RS18910	COG0793	Belongs to the peptidase S41A family
DP47_RS18920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DP47_RS18940	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DP47_RS18950	COG1040	competence protein
DP47_RS18955	COG2226	methyltransferase
DP47_RS18970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DP47_RS18980	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DP47_RS19010	COG1612	heme a metabolic process
DP47_RS19020	COG1999	signal sequence binding
DP47_RS19030	COG0840	transmembrane signaling receptor activity
DP47_RS19050	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DP47_RS19065	COG0587	DNA-directed DNA polymerase activity
DP47_RS19075	COG2814	Major facilitator Superfamily
DP47_RS19110	COG2226	methyltransferase
DP47_RS19120	COG1960	acyl-CoA dehydrogenase activity
DP47_RS19130	COG0318	PFAM AMP-dependent synthetase and ligase
DP47_RS19175	COG0583	DNA-binding transcription factor activity
DP47_RS19180	COG2188	Transcriptional regulator
DP47_RS19185	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DP47_RS19190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DP47_RS19195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DP47_RS19195	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP47_RS19200	COG1263	PTS System
DP47_RS19200	COG2190	(PTS) system
DP47_RS19200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP47_RS19220	COG1294	oxidase, subunit
DP47_RS19235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DP47_RS19240	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DP47_RS19250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DP47_RS19260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DP47_RS19265	COG0243	molybdopterin cofactor binding
DP47_RS19275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DP47_RS19285	COG0625	glutathione transferase activity
DP47_RS19295	COG0742	ribosomal rna small subunit methyltransferase
DP47_RS19305	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DP47_RS19315	COG0193	aminoacyl-tRNA hydrolase activity
DP47_RS19325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DP47_RS19340	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DP47_RS19355	COG1194	a g-specific adenine glycosylase
DP47_RS19380	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DP47_RS19385	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DP47_RS19390	COG1137	ATPase activity
DP47_RS19405	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DP47_RS19425	COG1280	lysine exporter protein (LysE YggA)
DP47_RS19450	COG2814	Major facilitator Superfamily
DP47_RS19455	COG0629	single-stranded DNA binding
DP47_RS19545	COG0235	Class ii aldolase
DP47_RS19550	COG5001	Diguanylate cyclase
DP47_RS19550	COG5002	protein histidine kinase activity
DP47_RS19585	COG2204	response regulator
DP47_RS19605	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DP47_RS19615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DP47_RS19630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DP47_RS19635	COG1596	polysaccharide export
DP47_RS19670	COG0477	Major facilitator Superfamily
DP47_RS19695	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DP47_RS19700	COG0251	oxidation-reduction process
DP47_RS19710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DP47_RS19775	COG0494	nUDIX hydrolase
DP47_RS19790	COG1960	acyl-CoA dehydrogenase activity
DP47_RS19795	COG1024	Enoyl-CoA hydratase
DP47_RS19795	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP47_RS19800	COG0183	Belongs to the thiolase family
DP47_RS19805	COG1024	Enoyl-CoA hydratase
DP47_RS19810	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DP47_RS19825	COG5265	(ABC) transporter
DP47_RS19835	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DP47_RS19840	COG3178	'Phosphotransferase
DP47_RS19855	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DP47_RS19880	COG0204	Acyl-transferase
DP47_RS19885	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DP47_RS19890	COG0751	glycine-tRNA ligase activity
DP47_RS19895	COG0752	glycyl-tRNA synthetase alpha subunit
DP47_RS19900	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DP47_RS19910	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DP47_RS19920	COG1702	phosphate starvation-inducible protein PhoH
DP47_RS19930	COG0583	DNA-binding transcription factor activity
DP47_RS19935	COG2814	Major facilitator Superfamily
DP47_RS19940	COG1396	sequence-specific DNA binding
DP47_RS19950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DP47_RS19965	COG0367	asparagine synthase
DP47_RS19970	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DP47_RS19975	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DP47_RS19985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DP47_RS19990	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DP47_RS20030	COG0513	Belongs to the DEAD box helicase family
DP47_RS20050	COG4948	Mandelate Racemase Muconate Lactonizing
DP47_RS20090	COG0840	transmembrane signaling receptor activity
DP47_RS20110	COG0583	DNA-binding transcription factor activity
DP47_RS20115	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DP47_RS20180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DP47_RS20185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DP47_RS20190	COG0028	Belongs to the TPP enzyme family
DP47_RS20230	COG0583	DNA-binding transcription factor activity
DP47_RS20235	COG5002	protein histidine kinase activity
DP47_RS20235	COG0784	Response regulator, receiver
DP47_RS20260	COG2801	Transposase and inactivated derivatives
DP47_RS20335	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DP47_RS20340	COG2137	regulation of response to DNA damage stimulus
DP47_RS20355	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DP47_RS20360	COG0861	Integral membrane protein TerC family
DP47_RS20365	COG4969	Belongs to the N-Me-Phe pilin family
DP47_RS20370	COG3307	-O-antigen
DP47_RS20390	COG4783	chaperone-mediated protein folding
DP47_RS20400	COG0429	hydrolase of the alpha beta-hydrolase fold
DP47_RS20410	COG0859	PFAM glycosyl transferase family 9
DP47_RS20435	COG0126	phosphoglycerate kinase activity
DP47_RS20440	COG0469	pyruvate kinase activity
DP47_RS20450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DP47_RS20455	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DP47_RS20460	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DP47_RS20465	COG0009	L-threonylcarbamoyladenylate synthase
DP47_RS20500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP47_RS20525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DP47_RS20530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP47_RS20540	COG2233	PERMEase
DP47_RS20545	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DP47_RS20560	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DP47_RS20565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DP47_RS20570	COG1121	(ABC) transporter
DP47_RS20580	COG0735	belongs to the Fur family
DP47_RS20590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DP47_RS20605	COG1175	transmembrane transport
DP47_RS20615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DP47_RS20620	COG3842	ATPase activity
DP47_RS20630	COG0583	DNA-binding transcription factor activity
DP47_RS20645	COG2390	Transcriptional regulator
DP47_RS20650	COG1070	Carbohydrate kinase
DP47_RS20655	COG0246	Mannitol dehydrogenase
DP47_RS20660	COG0583	DNA-binding transcription factor activity
DP47_RS20670	COG1012	belongs to the aldehyde dehydrogenase family
DP47_RS20675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DP47_RS20685	COG2271	Major facilitator Superfamily
DP47_RS20705	COG1522	sequence-specific DNA binding
DP47_RS20710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DP47_RS20720	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DP47_RS20735	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DP47_RS20745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DP47_RS20750	COG3118	belongs to the thioredoxin family
DP47_RS20755	COG1741	Belongs to the pirin family
DP47_RS20765	COG0860	N-Acetylmuramoyl-L-alanine amidase
DP47_RS20770	COG0802	atpase or kinase
DP47_RS20775	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DP47_RS20785	COG4974	Belongs to the 'phage' integrase family
DP47_RS20790	COG0318	PFAM AMP-dependent synthetase and ligase
DP47_RS20795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DP47_RS20810	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DP47_RS20815	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DP47_RS20830	COG0728	peptidoglycan biosynthetic process
DP47_RS20860	COG1663	tetraacyldisaccharide 4'-kinase activity
DP47_RS20865	COG1570	exodeoxyribonuclease VII activity
DP47_RS20870	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DP47_RS20915	COG2814	Major facilitator Superfamily
DP47_RS20930	COG2188	Transcriptional regulator
DP47_RS20935	COG0656	L-ascorbic acid biosynthetic process
DP47_RS20980	COG1278	Cold shock
DP47_RS20990	COG0542	response to heat
DP47_RS20995	COG1113	amino acid transport
DP47_RS21025	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DP47_RS21030	COG0196	riboflavin kinase activity
DP47_RS21035	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DP47_RS21040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DP47_RS21040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DP47_RS21045	COG1511	domain protein
DP47_RS21045	COG3264	Mechanosensitive ion channel
DP47_RS21070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DP47_RS21090	COG1047	Peptidyl-prolyl cis-trans
DP47_RS21095	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DP47_RS21130	COG0456	acetyltransferase
DP47_RS21135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DP47_RS21140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DP47_RS21140	COG0543	2 iron, 2 sulfur cluster binding
DP47_RS21155	COG1187	pseudouridine synthase activity
DP47_RS21165	COG0583	DNA-binding transcription factor activity
DP47_RS21175	COG2267	carboxylic ester hydrolase activity
DP47_RS21180	COG2258	MOSC domain
DP47_RS21185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DP47_RS21195	COG1396	sequence-specific DNA binding
DP47_RS21210	COG0583	DNA-binding transcription factor activity
DP47_RS21225	COG0175	sulfate reduction
DP47_RS21235	COG2895	sulfate adenylyltransferase (ATP) activity
DP47_RS21240	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DP47_RS21240	COG1648	precorrin-2 dehydrogenase activity
DP47_RS21255	COG0795	lipopolysaccharide-transporting ATPase activity
DP47_RS21275	COG4654	Cytochrome c, class I
DP47_RS21285	COG0583	DNA-binding transcription factor activity
DP47_RS21315	COG4206	TonB-dependent receptor
DP47_RS21325	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DP47_RS21330	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DP47_RS21335	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DP47_RS21350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DP47_RS21360	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DP47_RS21370	COG1492	cobalamin metabolic process
DP47_RS21375	COG2259	Doxx family
DP47_RS21380	COG0489	protein tyrosine kinase activity
DP47_RS21395	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DP47_RS21405	COG0729	surface antigen
DP47_RS21410	COG2911	Protein conserved in bacteria
DP47_RS21430	COG2885	chlorophyll binding
DP47_RS21430	COG3047	cAMP biosynthetic process
DP47_RS21435	COG0489	protein tyrosine kinase activity
DP47_RS21460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DP47_RS21495	COG2226	methyltransferase
DP47_RS21525	COG2271	Major facilitator Superfamily
DP47_RS21540	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DP47_RS21545	COG2827	Endonuclease containing a URI domain
DP47_RS21565	COG0347	Belongs to the P(II) protein family
DP47_RS21585	COG4215	(ABC) transporter
DP47_RS21600	COG1741	Belongs to the pirin family
DP47_RS21625	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP47_RS21630	COG1116	anion transmembrane transporter activity
DP47_RS21650	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DP47_RS21665	COG2814	Major facilitator Superfamily
DP47_RS21670	COG1881	PFAM PEBP family protein
DP47_RS21725	COG2963	transposase activity
DP47_RS21735	COG2801	Transposase and inactivated derivatives
DP47_RS21750	COG2801	Transposase and inactivated derivatives
DP47_RS21825	COG3547	Transposase (IS116 IS110 IS902 family)
DP47_RS21830	COG0582	viral genome integration into host DNA
DP47_RS21935	COG1773	rubredoxin
DP47_RS21945	COG0488	(ABC) transporter
DP47_RS21970	COG0583	DNA-binding transcription factor activity
DP47_RS21980	COG0583	DNA-binding transcription factor activity
DP47_RS21985	COG0477	Major facilitator Superfamily
DP47_RS22020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DP47_RS22025	COG0697	spore germination
DP47_RS22035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DP47_RS22055	COG4106	trans-aconitate 2-methyltransferase activity
DP47_RS22070	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DP47_RS22085	COG3135	benzoate transporter
DP47_RS22120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DP47_RS22125	COG2878	Part of a membrane complex involved in electron transport
DP47_RS22130	COG1309	transcriptional regulator
DP47_RS22140	COG3387	PFAM Glycoside hydrolase 15-related
DP47_RS22145	COG2706	6-phosphogluconolactonase activity
DP47_RS22150	COG1674	ftsk spoiiie
DP47_RS22180	COG0513	Belongs to the DEAD box helicase family
DP47_RS22185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DP47_RS22225	COG0438	transferase activity, transferring glycosyl groups
DP47_RS22230	COG0859	PFAM glycosyl transferase family 9
DP47_RS22260	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DP47_RS22265	COG1595	DNA-templated transcription, initiation
DP47_RS22295	COG2233	PERMEase
DP47_RS22315	COG0799	negative regulation of ribosome biogenesis
DP47_RS22330	COG0151	Belongs to the GarS family
DP47_RS22345	COG1028	Short-chain dehydrogenase reductase Sdr
DP47_RS22365	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DP47_RS22370	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DP47_RS22385	COG2205	protein histidine kinase activity
DP47_RS22390	COG0745	RESPONSE REGULATOR receiver
DP47_RS22420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DP47_RS22430	COG0154	amidase activity
DP47_RS22440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DP47_RS22445	COG1028	Short-chain dehydrogenase reductase Sdr
DP47_RS22465	COG0438	transferase activity, transferring glycosyl groups
DP47_RS22495	COG0028	Belongs to the TPP enzyme family
DP47_RS22515	COG1183	phosphatidylcholine synthase activity
DP47_RS22525	COG0659	secondary active sulfate transmembrane transporter activity
DP47_RS22530	COG0288	reversible hydration of carbon dioxide
DP47_RS22545	COG0683	leucine binding
DP47_RS22560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DP47_RS22560	COG0604	alcohol dehydrogenase
DP47_RS22560	COG4221	oxidoreductase activity
DP47_RS22560	COG3321	synthase
DP47_RS22565	COG0149	triose-phosphate isomerase activity
DP47_RS22600	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DP47_RS22610	COG1034	ATP synthesis coupled electron transport
DP47_RS22645	COG1007	ATP synthesis coupled electron transport
DP47_RS22665	COG1960	acyl-CoA dehydrogenase activity
DP47_RS22670	COG1960	acyl-CoA dehydrogenase activity
DP47_RS22675	COG2030	dehydratase
DP47_RS22675	COG1012	belongs to the aldehyde dehydrogenase family
DP47_RS22695	COG1960	acyl-CoA dehydrogenase activity
DP47_RS22705	COG0588	phosphoglycerate mutase activity
DP47_RS22710	COG1024	Enoyl-CoA hydratase
DP47_RS22720	COG0436	Aminotransferase
DP47_RS22735	COG2866	Carboxypeptidase
DP47_RS22785	COG0006	proline dipeptidase activity
DP47_RS22800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DP47_RS22810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DP47_RS22830	COG2863	cytochrome
DP47_RS22835	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DP47_RS22835	COG2010	Cytochrome c
DP47_RS22850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DP47_RS22885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP47_RS22890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP47_RS22915	COG1959	2 iron, 2 sulfur cluster binding
DP47_RS22930	COG1522	sequence-specific DNA binding
DP47_RS22935	COG3842	ATPase activity
DP47_RS22940	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP47_RS22945	COG1840	ABC-type Fe3 transport system, periplasmic component
DP47_RS22960	COG1289	transmembrane transporter activity
DP47_RS22970	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DP47_RS22975	COG1074	ATP-dependent DNA helicase activity
DP47_RS22980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DP47_RS22990	COG2200	EAL domain
DP47_RS23030	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
DP47_RS23035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DP47_RS23045	COG0697	spore germination
DP47_RS23050	COG2814	Major facilitator Superfamily
DP47_RS23070	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DP47_RS23075	COG3842	ATPase activity
DP47_RS23080	COG1177	transmembrane transport
DP47_RS23095	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DP47_RS23100	COG1840	ABC-type Fe3 transport system, periplasmic component
DP47_RS23105	COG1609	Transcriptional regulator
DP47_RS23150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DP47_RS23160	COG1522	sequence-specific DNA binding
DP47_RS23180	COG0583	DNA-binding transcription factor activity
DP47_RS23215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DP47_RS23250	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DP47_RS23255	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP47_RS23260	COG0583	DNA-binding transcription factor activity
DP47_RS23280	COG3052	prosthetic group binding
DP47_RS23300	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DP47_RS23310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DP47_RS23330	COG0477	Major facilitator Superfamily
DP47_RS23340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DP47_RS23345	COG0328	RNA-DNA hybrid ribonuclease activity
DP47_RS23350	COG2226	methyltransferase
DP47_RS23355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DP47_RS23360	COG0741	lytic transglycosylase activity
DP47_RS23360	COG1388	LysM domain
DP47_RS23385	COG0505	Belongs to the CarA family
DP47_RS23395	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DP47_RS23400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DP47_RS23410	COG1534	Rna-binding protein
DP47_RS23420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DP47_RS23425	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DP47_RS23435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DP47_RS23440	COG0573	inorganic phosphate transmembrane transporter activity
DP47_RS23445	COG0581	inorganic phosphate transmembrane transporter activity
DP47_RS23460	COG0745	RESPONSE REGULATOR receiver
DP47_RS23470	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DP47_RS23535	COG0534	Mate efflux family protein
DP47_RS23545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DP47_RS23550	COG4942	peptidase
DP47_RS23575	COG0582	viral genome integration into host DNA
DP47_RS23585	COG2801	Transposase and inactivated derivatives
DP47_RS23615	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DP47_RS23660	COG0366	Alpha amylase catalytic
DP47_RS23665	COG0366	Alpha amylase catalytic
DP47_RS23705	COG0583	DNA-binding transcription factor activity
DP47_RS23710	COG0745	RESPONSE REGULATOR receiver
DP47_RS23755	COG0859	PFAM glycosyl transferase family 9
DP47_RS23755	COG0457	Tetratricopeptide repeat
DP47_RS23940	COG2814	Major facilitator Superfamily
DP47_RS23945	COG0583	DNA-binding transcription factor activity
DP47_RS23985	COG2197	response regulator
DP47_RS23990	COG1538	Outer membrane efflux protein
DP47_RS23995	COG2814	Major facilitator Superfamily
DP47_RS24005	COG1566	PFAM secretion protein HlyD family protein
DP47_RS24015	COG3511	phospholipase C
DP47_RS24020	COG1858	cytochrome C peroxidase
DP47_RS24040	COG1051	belongs to the nudix hydrolase family
DP47_RS24045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DP47_RS24055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DP47_RS24070	COG0477	Major facilitator Superfamily
DP47_RS24080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP47_RS24090	COG2816	NAD+ diphosphatase activity
DP47_RS24105	COG0824	Thioesterase
DP47_RS24115	COG0411	ABC transporter
DP47_RS24125	COG3718	enzyme involved in inositol metabolism
DP47_RS24135	COG3962	Belongs to the TPP enzyme family
DP47_RS24150	COG1172	Belongs to the binding-protein-dependent transport system permease family
DP47_RS24165	COG0673	inositol 2-dehydrogenase activity
DP47_RS24170	COG0673	inositol 2-dehydrogenase activity
DP47_RS24175	COG0425	Belongs to the sulfur carrier protein TusA family
DP47_RS24185	COG0745	RESPONSE REGULATOR receiver
DP47_RS24195	COG5002	protein histidine kinase activity
DP47_RS24205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DP47_RS24210	COG0525	valine-tRNA ligase activity
DP47_RS24215	COG0210	DNA helicase
DP47_RS24220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DP47_RS24225	COG2223	nitrite transmembrane transporter activity
DP47_RS24230	COG0840	transmembrane signaling receptor activity
DP47_RS24255	COG0583	DNA-binding transcription factor activity
DP47_RS24270	COG0277	FAD linked oxidase domain protein
DP47_RS24285	COG1295	ribonuclease BN
DP47_RS24300	COG0477	Major facilitator Superfamily
DP47_RS24325	COG1028	Short-chain dehydrogenase reductase Sdr
DP47_RS24360	COG1028	Short-chain dehydrogenase reductase Sdr
DP47_RS24375	COG0583	DNA-binding transcription factor activity
DP47_RS24385	COG2267	carboxylic ester hydrolase activity
DP47_RS24390	COG0251	oxidation-reduction process
DP47_RS24395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DP47_RS24410	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DP47_RS24435	COG0776	regulation of translation
DP47_RS24450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DP47_RS24450	COG2755	lipolytic protein G-D-S-L family
DP47_RS24470	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DP47_RS24510	COG0583	DNA-binding transcription factor activity
DP47_RS24515	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DP47_RS24520	COG1187	pseudouridine synthase activity
DP47_RS24530	COG2251	uridine kinase activity
DP47_RS24530	COG0195	Participates in both transcription termination and antitermination
DP47_RS24545	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DP47_RS24550	COG2814	Major facilitator Superfamily
DP47_RS24555	COG1566	PFAM secretion protein HlyD family protein
DP47_RS24565	COG1846	Transcriptional regulator
DP47_RS24570	COG1217	gtp-binding protein TYPA
DP47_RS24580	COG0567	Dehydrogenase, E1 component
DP47_RS24585	COG0508	dehydrogenase complex catalyzes the overall conversion of
DP47_RS24590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DP47_RS24595	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DP47_RS24650	COG4964	Belongs to the GSP D family
DP47_RS24720	COG0318	PFAM AMP-dependent synthetase and ligase
DP47_RS24730	COG2814	Major facilitator Superfamily
DP47_RS24740	COG0519	Catalyzes the synthesis of GMP from XMP
DP47_RS24765	COG0840	transmembrane signaling receptor activity
DP47_RS24780	COG0557	exoribonuclease II activity
DP47_RS24785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DP47_RS24795	COG3023	N-Acetylmuramoyl-L-alanine amidase
DP47_RS24805	COG1802	Transcriptional regulator
DP47_RS24810	COG0673	inositol 2-dehydrogenase activity
DP47_RS24815	COG0765	amino acid transport
DP47_RS24820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP47_RS24875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DP47_RS24880	COG1116	anion transmembrane transporter activity
DP47_RS24910	COG1301	dicarboxylic acid transport
DP47_RS24930	COG0667	Aldo Keto reductase
DP47_RS24935	COG0701	Predicted permease
DP47_RS24975	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DP47_RS24980	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DP47_RS24985	COG4208	sulfate ABC transporter
DP47_RS24990	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DP47_RS24995	COG0583	DNA-binding transcription factor activity
DP47_RS25000	COG1879	ABC-type sugar transport system periplasmic component
DP47_RS25005	COG1129	ABC transporter
DP47_RS25010	COG1172	Belongs to the binding-protein-dependent transport system permease family
DP47_RS25015	COG1609	Transcriptional regulator
DP47_RS25020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DP47_RS25025	COG0840	transmembrane signaling receptor activity
DP47_RS25030	COG2766	serine protein kinase
DP47_RS25035	COG2718	Belongs to the UPF0229 family
DP47_RS25040	COG2719	SpoVR family
DP47_RS25045	COG0477	Major facilitator Superfamily
DP47_RS25060	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DP47_RS25065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DP47_RS25085	COG4964	Belongs to the GSP D family
DP47_RS25130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP47_RS25145	COG4597	amino acid ABC transporter
DP47_RS25150	COG0765	amino acid transport
DP47_RS25155	COG0739	heme binding
DP47_RS25160	COG1309	transcriptional regulator
DP47_RS25165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DP47_RS25170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP47_RS25180	COG3539	Fimbrial protein
DP47_RS25190	COG3121	Chaperone
DP47_RS25200	COG1132	(ABC) transporter
DP47_RS25200	COG2375	cellular response to nickel ion
DP47_RS25220	COG1879	ABC-type sugar transport system periplasmic component
DP47_RS25230	COG1172	Belongs to the binding-protein-dependent transport system permease family
DP47_RS25235	COG1063	alcohol dehydrogenase
DP47_RS25240	COG1070	Carbohydrate kinase
DP47_RS25245	COG1028	Short-chain dehydrogenase reductase Sdr
DP47_RS25275	COG1120	ATPase activity
DP47_RS25320	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DP47_RS25325	COG4774	siderophore transport
DP47_RS25330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DP47_RS25355	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DP47_RS25390	COG3209	COG3209 Rhs family protein
DP47_RS25400	COG4644	lycopene metabolic process
DP47_RS25405	COG0400	carboxylic ester hydrolase activity
DP47_RS25415	COG3979	chitinase
DP47_RS25435	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DP47_RS25445	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DP47_RS25465	COG1649	PFAM Uncharacterised BCR, COG1649
DP47_RS25470	COG2807	transmembrane transport
DP47_RS25475	COG1846	Transcriptional regulator
DP47_RS25490	COG0625	glutathione transferase activity
DP47_RS25500	COG0583	DNA-binding transcription factor activity
DP47_RS25525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DP47_RS25530	COG2235	arginine
DP47_RS25545	COG1174	glycine betaine transport
DP47_RS25550	COG1125	glycine betaine transport
DP47_RS25555	COG1174	glycine betaine transport
DP47_RS25560	COG1732	Glycine betaine
DP47_RS25570	COG0477	Major facilitator Superfamily
DP47_RS25575	COG0318	PFAM AMP-dependent synthetase and ligase
DP47_RS25585	COG0840	transmembrane signaling receptor activity
DP47_RS25590	COG0835	chemotaxis
DP47_RS25595	COG0697	spore germination
DP47_RS25600	COG2207	Transcriptional regulator
DP47_RS25605	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP47_RS25620	COG3251	PFAM MbtH domain protein
DP47_RS25630	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DP47_RS25645	COG0137	argininosuccinate synthase activity
DP47_RS25650	COG0165	Argininosuccinate lyase
DP47_RS25670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DP47_RS25695	COG2192	nodulation
DP47_RS25725	COG5295	Hep Hag repeat protein
DP47_RS25725	COG5295	Hep Hag repeat protein
DP47_RS25775	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DP47_RS25810	COG2801	Transposase and inactivated derivatives
DP47_RS25820	COG3220	belongs to the UPF0276 family
DP47_RS25840	COG4944	Protein of unknown function (DUF1109)
DP47_RS25845	COG1595	DNA-templated transcription, initiation
DP47_RS25860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DP47_RS25875	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DP47_RS25885	COG2986	histidine ammonia-lyase
DP47_RS25895	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP47_RS25920	COG0745	RESPONSE REGULATOR receiver
DP47_RS25925	COG0529	Catalyzes the synthesis of activated sulfate
DP47_RS25935	COG0457	Tetratricopeptide repeat
DP47_RS25935	COG0859	PFAM glycosyl transferase family 9
DP47_RS25945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DP47_RS25950	COG2274	protein secretion by the type I secretion system
DP47_RS25980	COG2916	Histone family protein nucleoid-structuring protein H-NS
DP47_RS25990	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP47_RS26005	COG3842	ATPase activity
DP47_RS26015	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP47_RS26030	COG1012	belongs to the aldehyde dehydrogenase family
DP47_RS26035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DP47_RS26095	COG2197	response regulator
DP47_RS26110	COG5295	Hep Hag repeat protein
DP47_RS26155	COG3121	Chaperone
DP47_RS26210	COG0475	glutathione-regulated potassium exporter activity
DP47_RS26230	COG2376	Dihydroxyacetone kinase
DP47_RS26240	COG0840	transmembrane signaling receptor activity
DP47_RS26260	COG4263	nitrous-oxide reductase activity
DP47_RS26275	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DP47_RS26335	COG2350	Protein conserved in bacteria
DP47_RS26340	COG0598	Magnesium transport protein CorA
DP47_RS26415	COG1609	Transcriptional regulator
DP47_RS26420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DP47_RS26430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DP47_RS26450	COG2855	membrane
DP47_RS26455	COG0038	chloride channel
DP47_RS26470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP47_RS26475	COG1538	Outer membrane efflux protein
DP47_RS26495	COG3655	Transcriptional regulator
DP47_RS26520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP47_RS26520	COG0730	response to heat
DP47_RS26525	COG1177	transmembrane transport
DP47_RS26530	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP47_RS26535	COG3842	ATPase activity
DP47_RS26540	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DP47_RS26545	COG1914	H( )-stimulated, divalent metal cation uptake system
DP47_RS26555	COG3047	cAMP biosynthetic process
DP47_RS26560	COG2070	2-Nitropropane dioxygenase
DP47_RS26575	COG0488	(ABC) transporter
DP47_RS26580	COG2982	Protein involved in outer membrane biogenesis
DP47_RS26585	COG1122	ATPase activity
DP47_RS26590	COG0390	transport system, permease component
DP47_RS26600	COG0560	Phosphoserine phosphatase
DP47_RS26605	COG0626	cystathionine gamma-synthase activity
DP47_RS26615	COG0183	Belongs to the thiolase family
DP47_RS26635	COG1028	Short-chain dehydrogenase reductase Sdr
DP47_RS26640	COG0183	Belongs to the thiolase family
DP47_RS26645	COG3243	poly(R)-hydroxyalkanoic acid synthase
DP47_RS26650	COG1496	oxidoreductase activity
DP47_RS26655	COG0564	pseudouridine synthase activity
DP47_RS26665	COG1199	ATP-dependent helicase activity
DP47_RS26680	COG2183	response to ionizing radiation
DP47_RS26695	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DP47_RS26715	COG0330	HflC and HflK could
DP47_RS26720	COG0330	HflC and HflK could
DP47_RS26725	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DP47_RS26740	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DP47_RS26775	COG0670	Belongs to the BI1 family
DP47_RS26820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DP47_RS26835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DP47_RS26850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DP47_RS26855	COG0789	Transcriptional regulator
DP47_RS26860	COG0477	Major facilitator Superfamily
DP47_RS26865	COG3228	Belongs to the MtfA family
DP47_RS26880	COG0534	Mate efflux family protein
DP47_RS26905	COG0542	response to heat
DP47_RS26910	COG1959	2 iron, 2 sulfur cluster binding
DP47_RS26915	COG2346	COG2346, Truncated hemoglobins
DP47_RS26920	COG0314	molybdopterin synthase activity
DP47_RS26925	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DP47_RS26945	COG0436	Aminotransferase
DP47_RS26955	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DP47_RS26960	COG2076	Multidrug Resistance protein
DP47_RS26965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DP47_RS26970	COG0463	Glycosyl transferase, family 2
DP47_RS26980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DP47_RS26980	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DP47_RS26985	COG0726	polysaccharide deacetylase
DP47_RS26990	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DP47_RS26995	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DP47_RS27000	COG0791	NLP P60 protein
DP47_RS27005	COG0306	phosphate transporter
DP47_RS27060	COG0583	DNA-binding transcription factor activity
DP47_RS27065	COG3960	tartronate-semialdehyde synthase activity
DP47_RS27070	COG3622	Belongs to the hyi family
DP47_RS27075	COG2084	Dehydrogenase
DP47_RS27085	COG1652	LysM domain
DP47_RS27095	COG0252	asparaginase activity
DP47_RS27120	COG0438	transferase activity, transferring glycosyl groups
DP47_RS27145	COG0084	hydrolase, TatD family'
DP47_RS27150	COG1247	-acetyltransferase
DP47_RS27165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DP47_RS27170	COG0354	folic acid binding
DP47_RS27185	COG0657	acetylesterase activity
DP47_RS27190	COG2130	NADP-dependent
DP47_RS27210	COG0183	Belongs to the thiolase family
DP47_RS27215	COG1335	isochorismatase
DP47_RS27220	COG1024	Enoyl-CoA hydratase
DP47_RS27220	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP47_RS27225	COG0318	PFAM AMP-dependent synthetase and ligase
DP47_RS27250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DP47_RS27260	COG0047	phosphoribosylformylglycinamidine synthase activity
DP47_RS27260	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DP47_RS27270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DP47_RS27290	COG4181	ATPase activity
DP47_RS27340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DP47_RS27360	COG1929	Belongs to the glycerate kinase type-1 family
DP47_RS27365	COG1846	Transcriptional regulator
DP47_RS27370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DP47_RS27495	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DP47_RS27510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DP47_RS27565	COG3360	Dodecin
DP47_RS27570	COG0583	DNA-binding transcription factor activity
DP47_RS27580	COG2351	hydroxyisourate hydrolase activity
DP47_RS27595	COG4266	Belongs to the allantoicase family
DP47_RS27600	COG3195	allantoin biosynthetic process
DP47_RS27600	COG3648	Uricase
DP47_RS27615	COG1953	Uracil, thiamine, allantoin
DP47_RS27625	COG1619	proteins homologs of microcin C7 resistance protein MccF
DP47_RS27645	COG2814	Major facilitator Superfamily
DP47_RS27655	COG1196	nuclear chromosome segregation
DP47_RS27715	COG0697	spore germination
DP47_RS27725	COG2867	negative regulation of translational initiation
DP47_RS27735	COG0330	HflC and HflK could
DP47_RS27770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DP47_RS27810	COG0750	zinc metalloprotease
DP47_RS27825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DP47_RS27855	COG0024	Methionine aminopeptidase
DP47_RS27865	COG1187	pseudouridine synthase activity
DP47_RS27870	COG0242	peptide deformylase activity
DP47_RS27910	COG1393	Belongs to the ArsC family
DP47_RS27920	COG2890	protein-(glutamine-N5) methyltransferase activity
DP47_RS27935	COG0386	Belongs to the glutathione peroxidase family
DP47_RS27940	COG0488	(ABC) transporter
DP47_RS27960	COG0477	Major facilitator Superfamily
DP47_RS27965	COG0351	phosphomethylpyrimidine kinase
DP47_RS27980	COG1573	uracil-dna glycosylase
DP47_RS27990	COG1214	PFAM Peptidase M22, glycoprotease
DP47_RS28000	COG0513	Belongs to the DEAD box helicase family
DP47_RS28005	COG2224	Isocitrate lyase
DP47_RS28015	COG0583	DNA-binding transcription factor activity
DP47_RS28025	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DP47_RS28085	COG1752	Esterase of the alpha-beta hydrolase superfamily
DP47_RS28090	COG0791	NLP P60 protein
DP47_RS28095	COG4172	Belongs to the ABC transporter superfamily
DP47_RS28100	COG4239	(ABC) transporter, permease
DP47_RS28105	COG4174	ABC transporter (Permease)
DP47_RS28110	COG4166	transmembrane transport
DP47_RS28130	COG0243	molybdopterin cofactor binding
DP47_RS28140	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DP47_RS28160	COG0024	Methionine aminopeptidase
DP47_RS28175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DP47_RS28195	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DP47_RS28210	COG3958	Transketolase
DP47_RS28215	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DP47_RS28235	COG2175	clavaminate synthase activity
DP47_RS28260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DP47_RS28265	COG0529	Catalyzes the synthesis of activated sulfate
DP47_RS28265	COG2895	sulfate adenylyltransferase (ATP) activity
DP47_RS28275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DP47_RS28310	COG0527	aspartate kinase activity
DP47_RS28315	COG0037	tRNA processing
DP47_RS28340	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DP47_RS28350	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DP47_RS28355	COG1045	serine acetyltransferase
DP47_RS28365	COG0483	inositol monophosphate 1-phosphatase activity
DP47_RS28395	COG2850	peptidyl-arginine hydroxylation
DP47_RS28400	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DP47_RS28405	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DP47_RS28410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DP47_RS28420	COG0180	Tryptophanyl-tRNA synthetase
DP47_RS28425	COG1994	Peptidase M50
DP47_RS28430	COG0009	L-threonylcarbamoyladenylate synthase
DP47_RS28435	COG0613	PHP domain protein
DP47_RS28440	COG0596	Alpha beta hydrolase
DP47_RS28445	COG2833	Protein of unknown function (DUF455)
DP47_RS28455	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DP47_RS28465	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DP47_RS28485	COG2267	carboxylic ester hydrolase activity
DP47_RS28490	COG2333	competence protein COMEC
DP47_RS28490	COG0658	competence protein
DP47_RS28495	COG0084	hydrolase, TatD family'
DP47_RS28500	COG1136	(ABC) transporter
DP47_RS28515	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DP47_RS28540	COG2975	iron-sulfur cluster assembly
DP47_RS28560	COG0316	Belongs to the HesB IscA family
DP47_RS28565	COG0822	iron-sulfur transferase activity
DP47_RS28570	COG1104	cysteine desulfurase activity
DP47_RS28580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DP47_RS28600	COG1414	Transcriptional regulator
DP47_RS28620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DP47_RS28625	COG0508	dehydrogenase complex catalyzes the overall conversion of
DP47_RS28630	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DP47_RS28640	COG4566	intracellular signal transduction
DP47_RS28650	COG0339	signal peptide processing
DP47_RS28655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DP47_RS28670	COG2223	nitrite transmembrane transporter activity
DP47_RS28675	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DP47_RS28680	COG1140	nitrate reductase beta subunit
DP47_RS28685	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DP47_RS28690	COG2181	nitrate reductase activity
DP47_RS28695	COG4585	Histidine kinase
DP47_RS28700	COG2197	response regulator
DP47_RS28720	COG0174	glutamine synthetase
DP47_RS28730	COG1058	Belongs to the CinA family
DP47_RS28730	COG1546	Belongs to the CinA family
DP47_RS28750	COG1643	Atp-dependent helicase
DP47_RS28755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DP47_RS28755	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DP47_RS28765	COG0477	Major facilitator Superfamily
DP47_RS28775	COG1960	acyl-CoA dehydrogenase activity
DP47_RS28780	COG0583	DNA-binding transcription factor activity
DP47_RS28815	COG0174	glutamine synthetase
DP47_RS28820	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DP47_RS28845	COG0402	S-adenosylhomocysteine deaminase activity
DP47_RS28860	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DP47_RS28895	COG0529	Catalyzes the synthesis of activated sulfate
DP47_RS28900	COG0415	Belongs to the DNA photolyase family
DP47_RS28915	COG2151	metal-sulfur cluster biosynthetic enzyme
DP47_RS28950	COG3154	lipid carrier protein
DP47_RS28955	COG0826	peptidase U32
DP47_RS28960	COG0826	peptidase U32
DP47_RS28975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DP47_RS28980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DP47_RS28985	COG0840	transmembrane signaling receptor activity
DP47_RS28995	COG0719	Fe-S assembly protein
DP47_RS29000	COG0396	ATPase activity
DP47_RS29010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DP47_RS29015	COG0822	iron-sulfur transferase activity
DP47_RS29020	COG2151	metal-sulfur cluster biosynthetic enzyme
DP47_RS29030	COG1959	2 iron, 2 sulfur cluster binding
DP47_RS29055	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DP47_RS29065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP47_RS29100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DP47_RS29135	COG3394	polysaccharide catabolic process
DP47_RS29150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DP47_RS29160	COG0596	Alpha beta hydrolase
DP47_RS29165	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DP47_RS29175	COG3511	phospholipase C
DP47_RS29180	COG0683	leucine binding
DP47_RS29185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DP47_RS29200	COG0438	transferase activity, transferring glycosyl groups
DP47_RS29205	COG1132	(ABC) transporter
DP47_RS29210	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DP47_RS29225	COG1999	signal sequence binding
DP47_RS29240	COG2153	protein acetylation
DP47_RS29250	COG0583	DNA-binding transcription factor activity
DP47_RS29255	COG1956	GAF domain-containing protein
DP47_RS29275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DP47_RS29295	COG2204	response regulator
DP47_RS29320	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DP47_RS29325	COG0571	ribonuclease III activity
DP47_RS29330	COG0681	Belongs to the peptidase S26 family
DP47_RS29345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP47_RS29350	COG3026	antisigma factor binding
DP47_RS29370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DP47_RS29405	COG1399	metal-binding, possibly nucleic acid-binding protein
DP47_RS29430	COG0546	phosphoglycolate phosphatase activity
DP47_RS29440	COG1530	ribonuclease E activity
DP47_RS29445	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DP47_RS29455	COG0303	'Molybdopterin
DP47_RS29470	COG1322	Protein conserved in bacteria
DP47_RS29490	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DP47_RS29495	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DP47_RS29510	COG3045	CreA protein
DP47_RS29525	COG2501	S4 domain
DP47_RS29530	COG0534	Mate efflux family protein
DP47_RS29540	COG0114	fumarate hydratase activity
DP47_RS29560	COG0640	Transcriptional regulator
DP47_RS29570	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DP47_RS29605	COG2204	response regulator
DP47_RS29610	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DP47_RS29620	COG0312	modulator of DNA gyrase
DP47_RS29625	COG3028	Belongs to the UPF0307 family
DP47_RS29630	COG0521	Mo-molybdopterin cofactor biosynthetic process
DP47_RS29645	COG0501	Belongs to the peptidase M48B family
DP47_RS29660	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DP47_RS29720	COG1960	acyl-CoA dehydrogenase activity
DP47_RS29740	COG2011	ABC-type metal ion transport system permease component
DP47_RS29750	COG2267	carboxylic ester hydrolase activity
DP47_RS29755	COG0123	including yeast histone deacetylase and acetoin utilization protein
DP47_RS29760	COG2951	lytic endotransglycosylase activity
DP47_RS29785	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DP47_RS29795	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DP47_RS29820	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DP47_RS29825	COG0077	Prephenate dehydratase
DP47_RS29825	COG1605	Chorismate mutase
DP47_RS29830	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DP47_RS29855	COG0546	phosphoglycolate phosphatase activity
DP47_RS30060	COG5410	chromosome segregation
DP47_RS30265	COG1690	Belongs to the RtcB family
DP47_RS30315	COG0582	viral genome integration into host DNA
DP47_RS30320	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DP47_RS30330	COG1910	domain protein
DP47_RS30345	COG3383	formate dehydrogenase (NAD+) activity
DP47_RS30370	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DP47_RS30375	COG0154	amidase activity
DP47_RS30395	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DP47_RS30400	COG2252	PERMEase
DP47_RS30405	COG0402	S-adenosylhomocysteine deaminase activity
DP47_RS30410	COG2119	membrane
DP47_RS30420	COG0308	aminopeptidase N
DP47_RS30430	COG0583	DNA-binding transcription factor activity
DP47_RS30475	COG4772	TonB-dependent receptor
DP47_RS30495	COG2176	DNA-directed DNA polymerase activity
DP47_RS30500	COG1278	Cold shock
DP47_RS30510	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DP47_RS30530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DP47_RS30545	COG1561	YicC-like family, N-terminal region
DP47_RS30555	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DP47_RS30560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DP47_RS30590	COG0477	Major facilitator Superfamily
DP47_RS30600	COG0859	PFAM glycosyl transferase family 9
DP47_RS30625	COG2894	cell division
DP47_RS30660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DP47_RS30665	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DP47_RS30670	COG1674	ftsk spoiiie
DP47_RS30675	COG0492	ferredoxin-NADP+ reductase activity
DP47_RS30680	COG1193	negative regulation of DNA recombination
DP47_RS30685	COG2860	membrane
DP47_RS30690	COG3842	ATPase activity
DP47_RS30695	COG0395	ABC-type sugar transport system, permease component
DP47_RS30700	COG1175	transmembrane transport
DP47_RS30710	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DP47_RS30715	COG0363	glucosamine-6-phosphate deaminase activity
DP47_RS30725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP47_RS30730	COG0765	amino acid transport
DP47_RS30735	COG1126	abc transporter atp-binding protein
DP47_RS30750	COG2814	Major facilitator Superfamily
DP47_RS30770	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DP47_RS30770	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DP47_RS30795	COG0436	Aminotransferase
DP47_RS30830	COG0762	integral membrane protein
DP47_RS30850	COG2226	methyltransferase
DP47_RS30855	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DP47_RS30885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DP47_RS30895	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DP47_RS30905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DP47_RS30915	COG0559	Belongs to the binding-protein-dependent transport system permease family
DP47_RS30925	COG1129	ABC transporter
DP47_RS30980	COG0859	PFAM glycosyl transferase family 9
DP47_RS31005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DP47_RS31020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DP47_RS31035	COG1215	transferase activity, transferring glycosyl groups
DP47_RS31110	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DP47_RS31130	COG1773	rubredoxin
DP47_RS31145	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DP47_RS31155	COG1733	regulation of RNA biosynthetic process
DP47_RS31160	COG0604	alcohol dehydrogenase
DP47_RS31210	COG1280	lysine exporter protein (LysE YggA)
DP47_RS31215	COG0584	glycerophosphoryl diester phosphodiesterase
DP47_RS31225	COG0730	response to heat
DP47_RS31265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DP47_RS31275	COG1120	ATPase activity
DP47_RS31280	COG4774	siderophore transport
DP47_RS31295	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DP47_RS31320	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity