locus-tag	class	description
BK015_RS00010	COG0592	DNA-directed DNA polymerase activity
BK015_RS00035	COG1475	DNA binding
BK015_RS00060	COG0753	catalase activity
BK015_RS00105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BK015_RS00110	COG1024	Enoyl-CoA hydratase
BK015_RS00110	COG1250	3-hydroxyacyl-CoA dehydrogenase
BK015_RS00115	COG0183	Belongs to the thiolase family
BK015_RS00125	COG1960	acyl-CoA dehydrogenase activity
BK015_RS00155	COG1695	Transcriptional regulator
BK015_RS00230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BK015_RS00255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BK015_RS00270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BK015_RS00280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BK015_RS00290	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BK015_RS00290	COG4106	trans-aconitate 2-methyltransferase activity
BK015_RS00295	COG0789	Transcriptional regulator
BK015_RS00305	COG1987	bacterial-type flagellum assembly
BK015_RS00320	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BK015_RS00340	COG1346	cytolysis
BK015_RS00350	COG0583	DNA-binding transcription factor activity
BK015_RS00355	COG2814	Major facilitator Superfamily
BK015_RS00360	COG1846	Transcriptional regulator
BK015_RS00405	COG2165	general secretion pathway protein
BK015_RS00420	COG1459	type II secretion system
BK015_RS00445	COG0523	cobalamin synthesis protein
BK015_RS00490	COG0519	Catalyzes the synthesis of GMP from XMP
BK015_RS00490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BK015_RS00495	COG1902	pentaerythritol trinitrate reductase activity
BK015_RS00515	COG0642	Histidine kinase
BK015_RS00540	COG3186	Phenylalanine-4-hydroxylase
BK015_RS00545	COG1522	sequence-specific DNA binding
BK015_RS00560	COG0583	DNA-binding transcription factor activity
BK015_RS00570	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BK015_RS00600	COG0559	Belongs to the binding-protein-dependent transport system permease family
BK015_RS00645	COG1192	Involved in chromosome partitioning
BK015_RS00650	COG1475	DNA binding
BK015_RS00655	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BK015_RS00665	COG0356	it plays a direct role in the translocation of protons across the membrane
BK015_RS00705	COG0318	PFAM AMP-dependent synthetase and ligase
BK015_RS00720	COG1832	CoA-binding protein
BK015_RS00740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BK015_RS00760	COG0506	proline dehydrogenase activity
BK015_RS00760	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BK015_RS00760	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BK015_RS00780	COG1960	acyl-CoA dehydrogenase activity
BK015_RS00800	COG0436	Aminotransferase
BK015_RS00815	COG0277	FAD linked oxidase domain protein
BK015_RS00825	COG0789	Transcriptional regulator
BK015_RS00850	COG0668	transmembrane transport
BK015_RS00870	COG0531	amino acid
BK015_RS00875	COG4303	Ethanolamine ammonia lyase large subunit
BK015_RS00880	COG4302	ethanolamine ammonia-lyase activity
BK015_RS00890	COG1012	belongs to the aldehyde dehydrogenase family
BK015_RS00915	COG1760	l-serine dehydratase
BK015_RS00935	COG0509	glycine decarboxylation via glycine cleavage system
BK015_RS00950	COG0673	inositol 2-dehydrogenase activity
BK015_RS00970	COG0210	DNA helicase
BK015_RS00975	COG3245	cytochrome
BK015_RS00995	COG0582	viral genome integration into host DNA
BK015_RS01040	COG3397	chitin binding
BK015_RS01065	COG2267	carboxylic ester hydrolase activity
BK015_RS01140	COG1028	Short-chain dehydrogenase reductase Sdr
BK015_RS01155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BK015_RS01200	COG0519	Catalyzes the synthesis of GMP from XMP
BK015_RS01210	COG0561	phosphatase activity
BK015_RS01215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BK015_RS01230	COG0438	transferase activity, transferring glycosyl groups
BK015_RS01250	COG1360	Flagellar Motor Protein
BK015_RS01255	COG2201	protein-glutamate methylesterase activity
BK015_RS01275	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BK015_RS01285	COG2201	protein-glutamate methylesterase activity
BK015_RS01295	COG0745	RESPONSE REGULATOR receiver
BK015_RS01300	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BK015_RS01320	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BK015_RS01325	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BK015_RS01350	COG1950	PFAM Membrane protein of
BK015_RS01355	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BK015_RS01375	COG2070	2-Nitropropane dioxygenase
BK015_RS01410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BK015_RS01415	COG1522	sequence-specific DNA binding
BK015_RS01425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BK015_RS01445	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BK015_RS01450	COG2823	Periplasmic or secreted lipoprotein
BK015_RS01465	COG1113	amino acid transport
BK015_RS01510	COG2084	Dehydrogenase
BK015_RS01515	COG1280	lysine exporter protein (LysE YggA)
BK015_RS01520	COG2814	Major facilitator Superfamily
BK015_RS01525	COG0583	DNA-binding transcription factor activity
BK015_RS01535	COG3047	cAMP biosynthetic process
BK015_RS01555	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BK015_RS01570	COG1881	PFAM PEBP family protein
BK015_RS01575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BK015_RS01585	COG0281	malic enzyme
BK015_RS01585	COG0280	phosphate acetyltransferase
BK015_RS01610	COG1522	sequence-specific DNA binding
BK015_RS01630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BK015_RS01635	COG2151	metal-sulfur cluster biosynthetic enzyme
BK015_RS01640	COG3396	Phenylacetate-CoA oxygenase
BK015_RS01645	COG3460	Phenylacetate-CoA oxygenase
BK015_RS01650	COG3396	Phenylacetate-CoA oxygenase
BK015_RS01700	COG2963	transposase activity
BK015_RS01705	COG2801	Transposase and inactivated derivatives
BK015_RS01745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BK015_RS01785	COG0514	ATP-dependent DNA helicase (RecQ)
BK015_RS01920	COG0201	protein transport
BK015_RS01965	COG4232	protein-disulfide reductase activity
BK015_RS01985	COG1333	cytochrome c biogenesis protein
BK015_RS01990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BK015_RS01995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BK015_RS02000	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BK015_RS02060	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BK015_RS02070	COG1175	transmembrane transport
BK015_RS02075	COG0395	ABC-type sugar transport system, permease component
BK015_RS02080	COG3842	ATPase activity
BK015_RS02085	COG0584	glycerophosphoryl diester phosphodiesterase
BK015_RS02100	COG0067	glutamate synthase
BK015_RS02100	COG0070	glutamate synthase
BK015_RS02100	COG0069	glutamate synthase activity
BK015_RS02110	COG1115	amino acid carrier protein
BK015_RS02120	COG4178	(ABC) transporter
BK015_RS02145	COG1127	ABC transporter
BK015_RS02150	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BK015_RS02155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BK015_RS02180	COG1131	(ABC) transporter
BK015_RS02185	COG0842	Transport permease protein
BK015_RS02210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BK015_RS02220	COG2095	MarC family integral membrane protein
BK015_RS02270	COG0805	protein transport
BK015_RS02275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BK015_RS02280	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BK015_RS02285	COG0723	plastoquinol--plastocyanin reductase activity
BK015_RS02290	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BK015_RS02295	COG2857	Cytochrome c1
BK015_RS02300	COG0625	glutathione transferase activity
BK015_RS02305	COG2969	positive regulation of protein catabolic process
BK015_RS02335	COG0582	viral genome integration into host DNA
BK015_RS02490	COG0308	aminopeptidase N
BK015_RS02560	COG0443	Heat shock 70 kDa protein
BK015_RS02570	COG1278	Cold shock
BK015_RS02575	COG0531	amino acid
BK015_RS02580	COG3384	dioxygenase
BK015_RS02590	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BK015_RS02595	COG2890	protein-(glutamine-N5) methyltransferase activity
BK015_RS02625	COG0006	proline dipeptidase activity
BK015_RS02630	COG1335	isochorismatase
BK015_RS02640	COG0488	(ABC) transporter
BK015_RS02655	COG0584	glycerophosphoryl diester phosphodiesterase
BK015_RS02695	COG0012	GTP binding
BK015_RS02725	COG0012	GTP binding
BK015_RS02750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BK015_RS02755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BK015_RS02770	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BK015_RS02790	COG0512	Glutamine amidotransferase of anthranilate synthase
BK015_RS02805	COG0546	phosphoglycolate phosphatase activity
BK015_RS02810	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BK015_RS02820	COG2967	ApaG domain
BK015_RS02825	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BK015_RS02835	COG2050	protein possibly involved in aromatic compounds catabolism
BK015_RS02840	COG1024	Enoyl-CoA hydratase
BK015_RS02845	COG0183	Belongs to the thiolase family
BK015_RS02855	COG1024	Enoyl-CoA hydratase
BK015_RS02895	COG0243	molybdopterin cofactor binding
BK015_RS02900	COG0318	PFAM AMP-dependent synthetase and ligase
BK015_RS02905	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BK015_RS02925	COG3116	cell division
BK015_RS02935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BK015_RS02940	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BK015_RS02975	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BK015_RS02990	COG0678	peroxiredoxin activity
BK015_RS03020	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BK015_RS03030	COG0494	nUDIX hydrolase
BK015_RS03035	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BK015_RS03050	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BK015_RS03060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BK015_RS03065	COG4536	flavin adenine dinucleotide binding
BK015_RS03075	COG0142	geranyltranstransferase activity
BK015_RS03120	COG2095	MarC family integral membrane protein
BK015_RS03125	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BK015_RS03130	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BK015_RS03185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BK015_RS03190	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BK015_RS03205	COG0439	Biotin carboxylase
BK015_RS03210	COG0511	ligase activity, forming carbon-carbon bonds
BK015_RS03215	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BK015_RS03220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BK015_RS03230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BK015_RS03235	COG3150	esterase
BK015_RS03240	COG0557	exoribonuclease II activity
BK015_RS03245	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BK015_RS03250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BK015_RS03270	COG1414	Transcriptional regulator
BK015_RS03275	COG3734	2-keto-3-deoxy-galactonokinase
BK015_RS03285	COG1028	Short-chain dehydrogenase reductase Sdr
BK015_RS03300	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK015_RS03305	COG1028	Short-chain dehydrogenase reductase Sdr
BK015_RS03315	COG0284	orotidine-5'-phosphate decarboxylase activity
BK015_RS03320	COG1546	Belongs to the CinA family
BK015_RS03325	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BK015_RS03355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BK015_RS03365	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BK015_RS03370	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BK015_RS03375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BK015_RS03385	COG2814	Major facilitator Superfamily
BK015_RS03415	COG1301	dicarboxylic acid transport
BK015_RS03420	COG4266	Belongs to the allantoicase family
BK015_RS03425	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BK015_RS03430	COG0735	belongs to the Fur family
BK015_RS03435	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BK015_RS03465	COG1466	dna polymerase III delta subunit
BK015_RS03470	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BK015_RS03475	COG1981	membrane
BK015_RS03490	COG0837	glucose binding
BK015_RS03490	COG1737	Transcriptional regulator
BK015_RS03505	COG0800	Aldolase
BK015_RS03525	COG2223	nitrite transmembrane transporter activity
BK015_RS03530	COG0583	DNA-binding transcription factor activity
BK015_RS03540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BK015_RS03545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK015_RS03550	COG0765	amino acid transport
BK015_RS03555	COG0765	amino acid transport
BK015_RS03560	COG1126	abc transporter atp-binding protein
BK015_RS03605	COG0121	glutamine amidotransferase
BK015_RS03615	COG0418	dihydroorotase activity
BK015_RS03650	COG4977	sequence-specific DNA binding
BK015_RS03650	COG1917	Cupin 2, conserved barrel domain protein
BK015_RS03655	COG0625	glutathione transferase activity
BK015_RS03660	COG0625	glutathione transferase activity
BK015_RS03675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BK015_RS03685	COG0588	phosphoglycerate mutase activity
BK015_RS03725	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BK015_RS03730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BK015_RS03735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BK015_RS03740	COG0006	proline dipeptidase activity
BK015_RS03750	COG0625	glutathione transferase activity
BK015_RS03755	COG0069	glutamate synthase activity
BK015_RS03840	COG3008	intermembrane lipid transfer
BK015_RS03840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BK015_RS03845	COG2995	paraquat-inducible protein a
BK015_RS03865	COG2353	YceI-like domain
BK015_RS03870	COG2353	YceI-like domain
BK015_RS03885	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BK015_RS03890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BK015_RS03895	COG1862	Preprotein translocase
BK015_RS03905	COG0343	queuine tRNA-ribosyltransferase activity
BK015_RS03915	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BK015_RS03920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BK015_RS03940	COG0783	Belongs to the Dps family
BK015_RS03965	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BK015_RS03970	COG2188	Transcriptional regulator
BK015_RS03980	COG3624	Phosphonate C-P lyase system protein PhnG
BK015_RS03990	COG3626	phosphonate metabolism
BK015_RS03995	COG3627	carbon phosphorus lyase activity
BK015_RS04000	COG4107	phosphonate C-P lyase system protein PhnK
BK015_RS04005	COG4778	phosphonate C-P lyase system protein PhnL
BK015_RS04010	COG3454	Phosphonate metabolism
BK015_RS04015	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BK015_RS04020	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BK015_RS04025	COG3639	organic phosphonate transmembrane transporter activity
BK015_RS04050	COG0247	lactate metabolic process
BK015_RS04055	COG0277	FAD linked oxidase domain protein
BK015_RS04060	COG0277	FAD linked oxidase domain protein
BK015_RS04065	COG0277	FAD linked oxidase domain protein
BK015_RS04070	COG2096	Adenosyltransferase
BK015_RS04075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BK015_RS04075	COG1017	nitric oxide dioxygenase activity
BK015_RS04080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BK015_RS04090	COG0312	modulator of DNA gyrase
BK015_RS04095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BK015_RS04100	COG3164	Protein of unknown function
BK015_RS04105	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BK015_RS04110	COG0497	DNA recombination
BK015_RS04115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BK015_RS04155	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BK015_RS04165	COG1428	Deoxynucleoside kinase
BK015_RS04170	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BK015_RS04175	COG0617	tRNA 3'-terminal CCA addition
BK015_RS04185	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BK015_RS04210	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BK015_RS04215	COG0586	Pfam SNARE associated Golgi protein
BK015_RS04320	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BK015_RS04335	COG1368	sulfuric ester hydrolase activity
BK015_RS04340	COG3321	synthase
BK015_RS04340	COG0604	alcohol dehydrogenase
BK015_RS04340	COG1028	Short-chain dehydrogenase reductase Sdr
BK015_RS04345	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BK015_RS04350	COG0156	8-amino-7-oxononanoate synthase activity
BK015_RS04405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BK015_RS04410	COG0489	protein tyrosine kinase activity
BK015_RS04410	COG3206	protein involved in exopolysaccharide biosynthesis
BK015_RS04420	COG3562	capsule polysaccharide
BK015_RS04425	COG1045	serine acetyltransferase
BK015_RS04440	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BK015_RS04445	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BK015_RS04450	COG0517	IMP dehydrogenase activity
BK015_RS04450	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BK015_RS04480	COG2885	chlorophyll binding
BK015_RS04505	COG0824	Thioesterase
BK015_RS04510	COG4221	oxidoreductase activity
BK015_RS04570	COG0450	alkyl hydroperoxide reductase
BK015_RS04580	COG1960	acyl-CoA dehydrogenase activity
BK015_RS04610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BK015_RS04620	COG2814	Major facilitator Superfamily
BK015_RS04650	COG2814	Major facilitator Superfamily
BK015_RS04655	COG0778	Nitroreductase
BK015_RS04660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BK015_RS04665	COG0583	DNA-binding transcription factor activity
BK015_RS04675	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BK015_RS04710	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BK015_RS04725	COG4774	siderophore transport
BK015_RS04730	COG1120	ATPase activity
BK015_RS04740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK015_RS04780	COG0730	response to heat
BK015_RS04795	COG0584	glycerophosphoryl diester phosphodiesterase
BK015_RS04800	COG1280	lysine exporter protein (LysE YggA)
BK015_RS04860	COG0604	alcohol dehydrogenase
BK015_RS04865	COG1733	regulation of RNA biosynthetic process
BK015_RS04880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BK015_RS04900	COG1773	rubredoxin
BK015_RS04920	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BK015_RS04995	COG1215	transferase activity, transferring glycosyl groups
BK015_RS05025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BK015_RS05055	COG0859	PFAM glycosyl transferase family 9
BK015_RS05110	COG1129	ABC transporter
BK015_RS05120	COG0559	Belongs to the binding-protein-dependent transport system permease family
BK015_RS05135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BK015_RS05145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BK015_RS05155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BK015_RS05195	COG1403	HNH endonuclease
BK015_RS05260	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BK015_RS05265	COG2226	methyltransferase
BK015_RS05290	COG0762	integral membrane protein
BK015_RS05345	COG0436	Aminotransferase
BK015_RS05375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BK015_RS05375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BK015_RS05400	COG2814	Major facilitator Superfamily
BK015_RS05415	COG1126	abc transporter atp-binding protein
BK015_RS05420	COG0765	amino acid transport
BK015_RS05425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK015_RS05440	COG0363	glucosamine-6-phosphate deaminase activity
BK015_RS05445	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BK015_RS05455	COG1175	transmembrane transport
BK015_RS05460	COG0395	ABC-type sugar transport system, permease component
BK015_RS05465	COG3842	ATPase activity
BK015_RS05470	COG2860	membrane
BK015_RS05475	COG1193	negative regulation of DNA recombination
BK015_RS05480	COG0492	ferredoxin-NADP+ reductase activity
BK015_RS05490	COG1674	ftsk spoiiie
BK015_RS05495	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BK015_RS05505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BK015_RS05585	COG3436	PFAM IS66 Orf2 family protein
BK015_RS05590	COG4372	Transposase
BK015_RS05595	COG3012	SEC-C Motif Domain Protein
BK015_RS05610	COG0582	viral genome integration into host DNA
BK015_RS05635	COG2894	cell division
BK015_RS05655	COG0859	PFAM glycosyl transferase family 9
BK015_RS05665	COG0477	Major facilitator Superfamily
BK015_RS05700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BK015_RS05705	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BK015_RS05715	COG1561	YicC-like family, N-terminal region
BK015_RS05730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BK015_RS05755	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BK015_RS05765	COG1278	Cold shock
BK015_RS05770	COG2176	DNA-directed DNA polymerase activity
BK015_RS05790	COG4772	TonB-dependent receptor
BK015_RS05850	COG0583	DNA-binding transcription factor activity
BK015_RS05860	COG0308	aminopeptidase N
BK015_RS05875	COG2119	membrane
BK015_RS05885	COG0402	S-adenosylhomocysteine deaminase activity
BK015_RS05890	COG2252	PERMEase
BK015_RS05895	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BK015_RS05920	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BK015_RS05955	COG3383	formate dehydrogenase (NAD+) activity
BK015_RS05970	COG1910	domain protein
BK015_RS05980	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BK015_RS05990	COG0546	phosphoglycolate phosphatase activity
BK015_RS06020	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BK015_RS06025	COG0077	Prephenate dehydratase
BK015_RS06025	COG1605	Chorismate mutase
BK015_RS06030	COG0287	Prephenate dehydrogenase
BK015_RS06035	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BK015_RS06060	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BK015_RS06070	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BK015_RS06095	COG2951	lytic endotransglycosylase activity
BK015_RS06100	COG0123	including yeast histone deacetylase and acetoin utilization protein
BK015_RS06110	COG2267	carboxylic ester hydrolase activity
BK015_RS06120	COG2011	ABC-type metal ion transport system permease component
BK015_RS06140	COG1960	acyl-CoA dehydrogenase activity
BK015_RS06210	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BK015_RS06225	COG0501	Belongs to the peptidase M48B family
BK015_RS06235	COG0521	Mo-molybdopterin cofactor biosynthetic process
BK015_RS06240	COG3028	Belongs to the UPF0307 family
BK015_RS06250	COG0312	modulator of DNA gyrase
BK015_RS06260	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BK015_RS06265	COG2204	response regulator
BK015_RS06295	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BK015_RS06305	COG0640	Transcriptional regulator
BK015_RS06325	COG0114	fumarate hydratase activity
BK015_RS06340	COG0534	Mate efflux family protein
BK015_RS06345	COG2501	S4 domain
BK015_RS06370	COG3045	CreA protein
BK015_RS06385	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BK015_RS06395	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BK015_RS06415	COG1322	Protein conserved in bacteria
BK015_RS06430	COG0303	'Molybdopterin
BK015_RS06440	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BK015_RS06445	COG1530	ribonuclease E activity
BK015_RS06460	COG0546	phosphoglycolate phosphatase activity
BK015_RS06485	COG1399	metal-binding, possibly nucleic acid-binding protein
BK015_RS06520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BK015_RS06540	COG3026	antisigma factor binding
BK015_RS06545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BK015_RS06560	COG0681	Belongs to the peptidase S26 family
BK015_RS06565	COG0571	ribonuclease III activity
BK015_RS06570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BK015_RS06595	COG2204	response regulator
BK015_RS06615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BK015_RS06640	COG1956	GAF domain-containing protein
BK015_RS06645	COG0583	DNA-binding transcription factor activity
BK015_RS06655	COG2153	protein acetylation
BK015_RS06670	COG1999	signal sequence binding
BK015_RS06685	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BK015_RS06690	COG1132	(ABC) transporter
BK015_RS06695	COG0438	transferase activity, transferring glycosyl groups
BK015_RS06710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BK015_RS06715	COG0683	leucine binding
BK015_RS06720	COG3511	phospholipase C
BK015_RS06745	COG0596	Alpha beta hydrolase
BK015_RS06755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BK015_RS06770	COG3394	polysaccharide catabolic process
BK015_RS06815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BK015_RS06855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK015_RS06865	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BK015_RS06895	COG1959	2 iron, 2 sulfur cluster binding
BK015_RS06910	COG2151	metal-sulfur cluster biosynthetic enzyme
BK015_RS06915	COG0822	iron-sulfur transferase activity
BK015_RS06920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BK015_RS06930	COG0396	ATPase activity
BK015_RS06935	COG0719	Fe-S assembly protein
BK015_RS06955	COG0840	transmembrane signaling receptor activity
BK015_RS06960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BK015_RS06965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BK015_RS06980	COG0826	peptidase U32
BK015_RS06985	COG0826	peptidase U32
BK015_RS06990	COG3154	lipid carrier protein
BK015_RS07030	COG2151	metal-sulfur cluster biosynthetic enzyme
BK015_RS07050	COG0415	Belongs to the DNA photolyase family
BK015_RS07055	COG0529	Catalyzes the synthesis of activated sulfate
BK015_RS07100	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BK015_RS07115	COG0402	S-adenosylhomocysteine deaminase activity
BK015_RS07150	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BK015_RS07155	COG0174	glutamine synthetase
BK015_RS07180	COG2801	Transposase and inactivated derivatives
BK015_RS07205	COG0583	DNA-binding transcription factor activity
BK015_RS07210	COG1960	acyl-CoA dehydrogenase activity
BK015_RS07225	COG2801	Transposase and inactivated derivatives
BK015_RS07240	COG0477	Major facilitator Superfamily
BK015_RS07250	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BK015_RS07250	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BK015_RS07255	COG1643	Atp-dependent helicase
BK015_RS07280	COG1058	Belongs to the CinA family
BK015_RS07280	COG1546	Belongs to the CinA family
BK015_RS07295	COG0174	glutamine synthetase
BK015_RS07315	COG2197	response regulator
BK015_RS07320	COG4585	Histidine kinase
BK015_RS07325	COG2181	nitrate reductase activity
BK015_RS07330	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BK015_RS07335	COG1140	nitrate reductase beta subunit
BK015_RS07340	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BK015_RS07345	COG2223	nitrite transmembrane transporter activity
BK015_RS07365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BK015_RS07370	COG0339	signal peptide processing
BK015_RS07385	COG4566	intracellular signal transduction
BK015_RS07400	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BK015_RS07405	COG0508	dehydrogenase complex catalyzes the overall conversion of
BK015_RS07410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BK015_RS07440	COG1414	Transcriptional regulator
BK015_RS07465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BK015_RS07475	COG1104	cysteine desulfurase activity
BK015_RS07480	COG0822	iron-sulfur transferase activity
BK015_RS07485	COG0316	Belongs to the HesB IscA family
BK015_RS07505	COG2975	iron-sulfur cluster assembly
BK015_RS07540	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BK015_RS07560	COG1136	(ABC) transporter
BK015_RS07565	COG0084	hydrolase, TatD family'
BK015_RS07570	COG0658	competence protein
BK015_RS07570	COG2333	competence protein COMEC
BK015_RS07575	COG2267	carboxylic ester hydrolase activity
BK015_RS07600	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BK015_RS07610	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BK015_RS07620	COG2833	Protein of unknown function (DUF455)
BK015_RS07630	COG0596	Alpha beta hydrolase
BK015_RS07640	COG0613	PHP domain protein
BK015_RS07645	COG0009	L-threonylcarbamoyladenylate synthase
BK015_RS07650	COG1994	Peptidase M50
BK015_RS07655	COG0180	Tryptophanyl-tRNA synthetase
BK015_RS07665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BK015_RS07670	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BK015_RS07675	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BK015_RS07685	COG2850	peptidyl-arginine hydroxylation
BK015_RS07725	COG0483	inositol monophosphate 1-phosphatase activity
BK015_RS07740	COG1045	serine acetyltransferase
BK015_RS07750	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BK015_RS07760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BK015_RS07785	COG0037	tRNA processing
BK015_RS07795	COG0527	aspartate kinase activity
BK015_RS07850	COG0529	Catalyzes the synthesis of activated sulfate
BK015_RS07850	COG2895	sulfate adenylyltransferase (ATP) activity
BK015_RS07855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BK015_RS07880	COG2175	clavaminate synthase activity
BK015_RS07900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BK015_RS07905	COG3958	Transketolase
BK015_RS07920	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BK015_RS07940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BK015_RS07960	COG0024	Methionine aminopeptidase
BK015_RS07980	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BK015_RS07995	COG0243	molybdopterin cofactor binding
BK015_RS08020	COG4166	transmembrane transport
BK015_RS08025	COG4174	ABC transporter (Permease)
BK015_RS08030	COG4239	(ABC) transporter, permease
BK015_RS08035	COG4172	Belongs to the ABC transporter superfamily
BK015_RS08040	COG0791	NLP P60 protein
BK015_RS08045	COG1752	Esterase of the alpha-beta hydrolase superfamily
BK015_RS08105	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BK015_RS08115	COG0583	DNA-binding transcription factor activity
BK015_RS08125	COG2224	Isocitrate lyase
BK015_RS08130	COG0513	Belongs to the DEAD box helicase family
BK015_RS08140	COG1214	PFAM Peptidase M22, glycoprotease
BK015_RS08150	COG1573	uracil-dna glycosylase
BK015_RS08170	COG0351	phosphomethylpyrimidine kinase
BK015_RS08175	COG0477	Major facilitator Superfamily
BK015_RS08195	COG0488	(ABC) transporter
BK015_RS08200	COG0386	Belongs to the glutathione peroxidase family
BK015_RS08215	COG2890	protein-(glutamine-N5) methyltransferase activity
BK015_RS08225	COG1393	Belongs to the ArsC family
BK015_RS08270	COG0242	peptide deformylase activity
BK015_RS08275	COG1187	pseudouridine synthase activity
BK015_RS08285	COG0024	Methionine aminopeptidase
BK015_RS08310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BK015_RS08325	COG0750	zinc metalloprotease
BK015_RS08365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BK015_RS08415	COG0330	HflC and HflK could
BK015_RS08425	COG2867	negative regulation of translational initiation
BK015_RS08435	COG0697	spore germination
BK015_RS08515	COG2814	Major facilitator Superfamily
BK015_RS08555	COG1619	proteins homologs of microcin C7 resistance protein MccF
BK015_RS08565	COG1953	Uracil, thiamine, allantoin
BK015_RS08580	COG3195	allantoin biosynthetic process
BK015_RS08580	COG3648	Uricase
BK015_RS08585	COG4266	Belongs to the allantoicase family
BK015_RS08600	COG2351	hydroxyisourate hydrolase activity
BK015_RS08615	COG0583	DNA-binding transcription factor activity
BK015_RS08625	COG3360	Dodecin
BK015_RS08705	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BK015_RS08720	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BK015_RS08865	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BK015_RS08875	COG1846	Transcriptional regulator
BK015_RS08880	COG1929	Belongs to the glycerate kinase type-1 family
BK015_RS08900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BK015_RS08975	COG4181	ATPase activity
BK015_RS08995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BK015_RS09005	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BK015_RS09005	COG0047	phosphoribosylformylglycinamidine synthase activity
BK015_RS09015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BK015_RS09040	COG0318	PFAM AMP-dependent synthetase and ligase
BK015_RS09050	COG1024	Enoyl-CoA hydratase
BK015_RS09050	COG1250	3-hydroxyacyl-CoA dehydrogenase
BK015_RS09055	COG1335	isochorismatase
BK015_RS09060	COG0183	Belongs to the thiolase family
BK015_RS09090	COG2130	NADP-dependent
BK015_RS09095	COG0657	acetylesterase activity
BK015_RS09110	COG0354	folic acid binding
BK015_RS09115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BK015_RS09130	COG1247	-acetyltransferase
BK015_RS09135	COG0084	hydrolase, TatD family'
BK015_RS09165	COG0438	transferase activity, transferring glycosyl groups
BK015_RS09195	COG0252	asparaginase activity
BK015_RS09205	COG1652	LysM domain
BK015_RS09215	COG2084	Dehydrogenase
BK015_RS09220	COG3622	Belongs to the hyi family
BK015_RS09225	COG3960	tartronate-semialdehyde synthase activity
BK015_RS09230	COG0583	DNA-binding transcription factor activity
BK015_RS09250	COG1595	DNA-templated transcription, initiation
BK015_RS09295	COG0306	phosphate transporter
BK015_RS09305	COG0791	NLP P60 protein
BK015_RS09310	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BK015_RS09320	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BK015_RS09325	COG0726	polysaccharide deacetylase
BK015_RS09330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BK015_RS09330	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BK015_RS09340	COG0463	Glycosyl transferase, family 2
BK015_RS09345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BK015_RS09350	COG2076	Multidrug Resistance protein
BK015_RS09355	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BK015_RS09365	COG0436	Aminotransferase
BK015_RS09395	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BK015_RS09400	COG0314	molybdopterin synthase activity
BK015_RS09405	COG2346	COG2346, Truncated hemoglobins
BK015_RS09410	COG1959	2 iron, 2 sulfur cluster binding
BK015_RS09415	COG0542	response to heat
BK015_RS09440	COG0534	Mate efflux family protein
BK015_RS09460	COG3228	Belongs to the MtfA family
BK015_RS09465	COG0477	Major facilitator Superfamily
BK015_RS09470	COG0789	Transcriptional regulator
BK015_RS09475	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BK015_RS09495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BK015_RS09510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BK015_RS09555	COG0670	Belongs to the BI1 family
BK015_RS09590	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BK015_RS09605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BK015_RS09610	COG0330	HflC and HflK could
BK015_RS09615	COG0330	HflC and HflK could
BK015_RS09635	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BK015_RS09660	COG2183	response to ionizing radiation
BK015_RS09675	COG1199	ATP-dependent helicase activity
BK015_RS09685	COG0564	pseudouridine synthase activity
BK015_RS09690	COG1496	oxidoreductase activity
BK015_RS09695	COG3243	poly(R)-hydroxyalkanoic acid synthase
BK015_RS09700	COG0183	Belongs to the thiolase family
BK015_RS09705	COG1028	Short-chain dehydrogenase reductase Sdr
BK015_RS09730	COG0183	Belongs to the thiolase family
BK015_RS09740	COG0626	cystathionine gamma-synthase activity
BK015_RS09745	COG0560	Phosphoserine phosphatase
BK015_RS09770	COG0390	transport system, permease component
BK015_RS09775	COG1122	ATPase activity
BK015_RS09780	COG2982	Protein involved in outer membrane biogenesis
BK015_RS09790	COG0488	(ABC) transporter
BK015_RS09810	COG2070	2-Nitropropane dioxygenase
BK015_RS09815	COG3047	cAMP biosynthetic process
BK015_RS09830	COG1914	H( )-stimulated, divalent metal cation uptake system
BK015_RS09835	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BK015_RS09840	COG3842	ATPase activity
BK015_RS09845	COG1176	ABC-type spermidine putrescine transport system, permease component I
BK015_RS09850	COG1177	transmembrane transport
BK015_RS09855	COG0730	response to heat
BK015_RS09855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BK015_RS09880	COG3655	Transcriptional regulator
BK015_RS09910	COG1538	Outer membrane efflux protein
BK015_RS09915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BK015_RS09930	COG0038	chloride channel
BK015_RS09935	COG2855	membrane
BK015_RS09955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BK015_RS09975	COG1609	Transcriptional regulator
BK015_RS10060	COG0598	Magnesium transport protein CorA
BK015_RS10095	COG1196	nuclear chromosome segregation
BK015_RS10095	COG3264	Mechanosensitive ion channel
BK015_RS10125	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BK015_RS10140	COG4263	nitrous-oxide reductase activity
BK015_RS10165	COG0840	transmembrane signaling receptor activity
BK015_RS10175	COG2376	Dihydroxyacetone kinase
BK015_RS10195	COG0475	glutathione-regulated potassium exporter activity
BK015_RS10275	COG3121	Chaperone
BK015_RS10280	COG3188	usher protein
BK015_RS10335	COG2197	response regulator
BK015_RS10395	COG2916	Histone family protein nucleoid-structuring protein H-NS
BK015_RS10425	COG2274	protein secretion by the type I secretion system
BK015_RS10430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK015_RS10440	COG0457	Tetratricopeptide repeat
BK015_RS10440	COG0859	PFAM glycosyl transferase family 9
BK015_RS10445	COG0529	Catalyzes the synthesis of activated sulfate
BK015_RS10450	COG0745	RESPONSE REGULATOR receiver
BK015_RS10485	COG1595	DNA-templated transcription, initiation
BK015_RS10490	COG4944	Protein of unknown function (DUF1109)
BK015_RS10510	COG3220	belongs to the UPF0276 family
BK015_RS10530	COG2192	nodulation
BK015_RS10545	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BK015_RS10555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BK015_RS10575	COG0165	Argininosuccinate lyase
BK015_RS10580	COG0137	argininosuccinate synthase activity
BK015_RS10595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BK015_RS10605	COG3251	PFAM MbtH domain protein
BK015_RS10625	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BK015_RS10635	COG2207	Transcriptional regulator
BK015_RS10640	COG0697	spore germination
BK015_RS10645	COG0835	chemotaxis
BK015_RS10665	COG0318	PFAM AMP-dependent synthetase and ligase
BK015_RS10670	COG0477	Major facilitator Superfamily
BK015_RS10680	COG1732	Glycine betaine
BK015_RS10685	COG1174	glycine betaine transport
BK015_RS10690	COG1125	glycine betaine transport
BK015_RS10695	COG1174	glycine betaine transport
BK015_RS10715	COG2235	arginine
BK015_RS10720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BK015_RS10745	COG0583	DNA-binding transcription factor activity
BK015_RS10750	COG0625	glutathione transferase activity
BK015_RS10770	COG1846	Transcriptional regulator
BK015_RS10775	COG2807	transmembrane transport
BK015_RS10780	COG1649	PFAM Uncharacterised BCR, COG1649
BK015_RS10800	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BK015_RS10810	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BK015_RS10830	COG3979	chitinase
BK015_RS10850	COG0400	carboxylic ester hydrolase activity
BK015_RS10885	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BK015_RS10910	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BK015_RS10915	COG4774	siderophore transport
BK015_RS10920	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BK015_RS10970	COG1120	ATPase activity
BK015_RS11000	COG1028	Short-chain dehydrogenase reductase Sdr
BK015_RS11005	COG1070	Carbohydrate kinase
BK015_RS11010	COG1063	alcohol dehydrogenase
BK015_RS11020	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK015_RS11030	COG1879	ABC-type sugar transport system periplasmic component
BK015_RS11055	COG1132	(ABC) transporter
BK015_RS11055	COG2375	cellular response to nickel ion
BK015_RS11065	COG3121	Chaperone
BK015_RS11075	COG3539	Fimbrial protein
BK015_RS11105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BK015_RS11115	COG1309	transcriptional regulator
BK015_RS11120	COG0739	heme binding
BK015_RS11125	COG0765	amino acid transport
BK015_RS11130	COG4597	amino acid ABC transporter
BK015_RS11145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK015_RS11190	COG4964	Belongs to the GSP D family
BK015_RS11210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BK015_RS11215	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BK015_RS11230	COG0477	Major facilitator Superfamily
BK015_RS11240	COG2719	SpoVR family
BK015_RS11245	COG2718	Belongs to the UPF0229 family
BK015_RS11250	COG2766	serine protein kinase
BK015_RS11265	COG0840	transmembrane signaling receptor activity
BK015_RS11270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BK015_RS11275	COG1609	Transcriptional regulator
BK015_RS11280	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK015_RS11285	COG1129	ABC transporter
BK015_RS11290	COG1879	ABC-type sugar transport system periplasmic component
BK015_RS11295	COG0583	DNA-binding transcription factor activity
BK015_RS11300	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BK015_RS11305	COG4208	sulfate ABC transporter
BK015_RS11310	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BK015_RS11315	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BK015_RS11370	COG0701	Predicted permease
BK015_RS11375	COG0667	Aldo Keto reductase
BK015_RS11405	COG1301	dicarboxylic acid transport
BK015_RS11440	COG1116	anion transmembrane transporter activity
BK015_RS11445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BK015_RS11505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK015_RS11510	COG0765	amino acid transport
BK015_RS11515	COG0673	inositol 2-dehydrogenase activity
BK015_RS11520	COG1802	Transcriptional regulator
BK015_RS11530	COG3023	N-Acetylmuramoyl-L-alanine amidase
BK015_RS11540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BK015_RS11545	COG0557	exoribonuclease II activity
BK015_RS11560	COG0840	transmembrane signaling receptor activity
BK015_RS11590	COG0519	Catalyzes the synthesis of GMP from XMP
BK015_RS11595	COG2814	Major facilitator Superfamily
BK015_RS11605	COG0318	PFAM AMP-dependent synthetase and ligase
BK015_RS11670	COG4964	Belongs to the GSP D family
BK015_RS11735	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BK015_RS11740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BK015_RS11745	COG0508	dehydrogenase complex catalyzes the overall conversion of
BK015_RS11750	COG0567	Dehydrogenase, E1 component
BK015_RS11755	COG1217	gtp-binding protein TYPA
BK015_RS11765	COG1846	Transcriptional regulator
BK015_RS11775	COG1566	PFAM secretion protein HlyD family protein
BK015_RS11780	COG2814	Major facilitator Superfamily
BK015_RS11790	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BK015_RS11805	COG0195	Participates in both transcription termination and antitermination
BK015_RS11805	COG2251	uridine kinase activity
BK015_RS11815	COG1187	pseudouridine synthase activity
BK015_RS11820	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BK015_RS11825	COG0583	DNA-binding transcription factor activity
BK015_RS11870	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BK015_RS11890	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BK015_RS11890	COG2755	lipolytic protein G-D-S-L family
BK015_RS11900	COG2801	Transposase and inactivated derivatives
BK015_RS11915	COG0776	regulation of translation
BK015_RS11940	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BK015_RS11955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BK015_RS11960	COG0251	oxidation-reduction process
BK015_RS11965	COG2267	carboxylic ester hydrolase activity
BK015_RS11975	COG0583	DNA-binding transcription factor activity
BK015_RS11990	COG1028	Short-chain dehydrogenase reductase Sdr
BK015_RS12045	COG1028	Short-chain dehydrogenase reductase Sdr
BK015_RS12070	COG0477	Major facilitator Superfamily
BK015_RS12095	COG1295	ribonuclease BN
BK015_RS12110	COG0277	FAD linked oxidase domain protein
BK015_RS12125	COG0583	DNA-binding transcription factor activity
BK015_RS12155	COG0840	transmembrane signaling receptor activity
BK015_RS12160	COG2223	nitrite transmembrane transporter activity
BK015_RS12165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BK015_RS12170	COG0210	DNA helicase
BK015_RS12180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BK015_RS12190	COG5002	protein histidine kinase activity
BK015_RS12200	COG0745	RESPONSE REGULATOR receiver
BK015_RS12210	COG0425	Belongs to the sulfur carrier protein TusA family
BK015_RS12220	COG0673	inositol 2-dehydrogenase activity
BK015_RS12225	COG0673	inositol 2-dehydrogenase activity
BK015_RS12240	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK015_RS12255	COG3962	Belongs to the TPP enzyme family
BK015_RS12265	COG3718	enzyme involved in inositol metabolism
BK015_RS12275	COG0411	ABC transporter
BK015_RS12285	COG0824	Thioesterase
BK015_RS12310	COG2816	NAD+ diphosphatase activity
BK015_RS12320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BK015_RS12330	COG0477	Major facilitator Superfamily
BK015_RS12345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BK015_RS12355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BK015_RS12365	COG1051	belongs to the nudix hydrolase family
BK015_RS12395	COG1858	cytochrome C peroxidase
BK015_RS12400	COG3511	phospholipase C
BK015_RS12415	COG1566	PFAM secretion protein HlyD family protein
BK015_RS12425	COG2814	Major facilitator Superfamily
BK015_RS12430	COG1538	Outer membrane efflux protein
BK015_RS12440	COG2197	response regulator
BK015_RS12495	COG0583	DNA-binding transcription factor activity
BK015_RS12500	COG2814	Major facilitator Superfamily
BK015_RS12535	COG1914	H( )-stimulated, divalent metal cation uptake system
BK015_RS12550	COG2801	Transposase and inactivated derivatives
BK015_RS12570	COG3436	PFAM IS66 Orf2 family protein
BK015_RS12575	COG4372	Transposase
BK015_RS12580	COG3012	SEC-C Motif Domain Protein
BK015_RS12780	COG0457	Tetratricopeptide repeat
BK015_RS12780	COG0859	PFAM glycosyl transferase family 9
BK015_RS12825	COG0745	RESPONSE REGULATOR receiver
BK015_RS12830	COG0583	DNA-binding transcription factor activity
BK015_RS12880	COG0366	Alpha amylase catalytic
BK015_RS12885	COG0366	Alpha amylase catalytic
BK015_RS12890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BK015_RS12935	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BK015_RS12975	COG0582	viral genome integration into host DNA
BK015_RS13035	COG0484	heat shock protein binding
BK015_RS13065	COG4942	peptidase
BK015_RS13075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BK015_RS13090	COG0534	Mate efflux family protein
BK015_RS13170	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BK015_RS13185	COG0745	RESPONSE REGULATOR receiver
BK015_RS13200	COG0581	inorganic phosphate transmembrane transporter activity
BK015_RS13205	COG0573	inorganic phosphate transmembrane transporter activity
BK015_RS13210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BK015_RS13225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BK015_RS13230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BK015_RS13240	COG1534	Rna-binding protein
BK015_RS13250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BK015_RS13255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BK015_RS13265	COG0505	Belongs to the CarA family
BK015_RS13295	COG0741	lytic transglycosylase activity
BK015_RS13295	COG1388	LysM domain
BK015_RS13300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BK015_RS13305	COG2226	methyltransferase
BK015_RS13310	COG0328	RNA-DNA hybrid ribonuclease activity
BK015_RS13315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BK015_RS13335	COG0477	Major facilitator Superfamily
BK015_RS13370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BK015_RS13380	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BK015_RS13400	COG3052	prosthetic group binding
BK015_RS13425	COG0583	DNA-binding transcription factor activity
BK015_RS13435	COG1250	3-hydroxyacyl-CoA dehydrogenase
BK015_RS13440	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BK015_RS13480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BK015_RS13515	COG0583	DNA-binding transcription factor activity
BK015_RS13545	COG1522	sequence-specific DNA binding
BK015_RS13615	COG1609	Transcriptional regulator
BK015_RS13620	COG1840	ABC-type Fe3 transport system, periplasmic component
BK015_RS13625	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BK015_RS13640	COG1177	transmembrane transport
BK015_RS13650	COG3842	ATPase activity
BK015_RS13660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BK015_RS13680	COG2814	Major facilitator Superfamily
BK015_RS13690	COG0697	spore germination
BK015_RS13705	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BK015_RS13710	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BK015_RS13760	COG2200	EAL domain
BK015_RS13770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BK015_RS13775	COG1074	ATP-dependent DNA helicase activity
BK015_RS13780	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BK015_RS13795	COG1289	transmembrane transporter activity
BK015_RS13820	COG1840	ABC-type Fe3 transport system, periplasmic component
BK015_RS13825	COG1176	ABC-type spermidine putrescine transport system, permease component I
BK015_RS13830	COG3842	ATPase activity
BK015_RS13835	COG1522	sequence-specific DNA binding
BK015_RS13855	COG1959	2 iron, 2 sulfur cluster binding
BK015_RS13890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BK015_RS13895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BK015_RS13935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BK015_RS13950	COG2010	Cytochrome c
BK015_RS13950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BK015_RS13955	COG2863	cytochrome
BK015_RS13985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BK015_RS14005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BK015_RS14025	COG0006	proline dipeptidase activity
BK015_RS14085	COG2866	Carboxypeptidase
BK015_RS14100	COG0436	Aminotransferase
BK015_RS14110	COG1024	Enoyl-CoA hydratase
BK015_RS14115	COG0588	phosphoglycerate mutase activity
BK015_RS14125	COG1960	acyl-CoA dehydrogenase activity
BK015_RS14145	COG2030	dehydratase
BK015_RS14145	COG1012	belongs to the aldehyde dehydrogenase family
BK015_RS14150	COG1960	acyl-CoA dehydrogenase activity
BK015_RS14155	COG1960	acyl-CoA dehydrogenase activity
BK015_RS14175	COG1007	ATP synthesis coupled electron transport
BK015_RS14210	COG1034	ATP synthesis coupled electron transport
BK015_RS14220	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BK015_RS14255	COG0149	triose-phosphate isomerase activity
BK015_RS14260	COG4221	oxidoreductase activity
BK015_RS14260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BK015_RS14260	COG0604	alcohol dehydrogenase
BK015_RS14260	COG3321	synthase
BK015_RS14280	COG0683	leucine binding
BK015_RS14295	COG0288	reversible hydration of carbon dioxide
BK015_RS14300	COG0659	secondary active sulfate transmembrane transporter activity
BK015_RS14315	COG1183	phosphatidylcholine synthase activity
BK015_RS14335	COG0028	Belongs to the TPP enzyme family
BK015_RS14365	COG0438	transferase activity, transferring glycosyl groups
BK015_RS14385	COG1028	Short-chain dehydrogenase reductase Sdr
BK015_RS14395	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BK015_RS14405	COG0154	amidase activity
BK015_RS14415	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BK015_RS14445	COG0745	RESPONSE REGULATOR receiver
BK015_RS14450	COG2205	protein histidine kinase activity
BK015_RS14465	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BK015_RS14470	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BK015_RS14500	COG1028	Short-chain dehydrogenase reductase Sdr
BK015_RS14520	COG0151	Belongs to the GarS family
BK015_RS14535	COG0799	negative regulation of ribosome biogenesis
BK015_RS14560	COG2233	PERMEase
BK015_RS14615	COG1595	DNA-templated transcription, initiation
BK015_RS14625	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BK015_RS14670	COG0859	PFAM glycosyl transferase family 9
BK015_RS14675	COG0438	transferase activity, transferring glycosyl groups
BK015_RS14715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BK015_RS14720	COG0513	Belongs to the DEAD box helicase family
BK015_RS14755	COG1674	ftsk spoiiie
BK015_RS14760	COG2706	6-phosphogluconolactonase activity
BK015_RS14770	COG3387	PFAM Glycoside hydrolase 15-related
BK015_RS14780	COG1309	transcriptional regulator
BK015_RS14785	COG2878	Part of a membrane complex involved in electron transport
BK015_RS14790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BK015_RS14825	COG3135	benzoate transporter
BK015_RS14840	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BK015_RS14855	COG4106	trans-aconitate 2-methyltransferase activity
BK015_RS14875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BK015_RS14885	COG0697	spore germination
BK015_RS14890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BK015_RS14935	COG0477	Major facilitator Superfamily
BK015_RS14945	COG0583	DNA-binding transcription factor activity
BK015_RS14955	COG0583	DNA-binding transcription factor activity
BK015_RS14990	COG0488	(ABC) transporter
BK015_RS15000	COG1773	rubredoxin
BK015_RS15385	COG1881	PFAM PEBP family protein
BK015_RS15390	COG2814	Major facilitator Superfamily
BK015_RS15400	COG3012	SEC-C Motif Domain Protein
BK015_RS15405	COG4372	Transposase
BK015_RS15410	COG3436	PFAM IS66 Orf2 family protein
BK015_RS15430	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BK015_RS15480	COG2801	Transposase and inactivated derivatives
BK015_RS15490	COG0443	Heat shock 70 kDa protein
BK015_RS15505	COG0582	viral genome integration into host DNA
BK015_RS15510	COG1116	anion transmembrane transporter activity
BK015_RS15515	COG1176	ABC-type spermidine putrescine transport system, permease component I
BK015_RS15545	COG1741	Belongs to the pirin family
BK015_RS15560	COG4215	(ABC) transporter
BK015_RS15580	COG0347	Belongs to the P(II) protein family
BK015_RS15600	COG1472	Belongs to the glycosyl hydrolase 3 family
BK015_RS15610	COG2827	Endonuclease containing a URI domain
BK015_RS15615	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BK015_RS15630	COG2271	Major facilitator Superfamily
BK015_RS15670	COG2226	methyltransferase
BK015_RS15710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BK015_RS15735	COG0489	protein tyrosine kinase activity
BK015_RS15740	COG3047	cAMP biosynthetic process
BK015_RS15740	COG2885	chlorophyll binding
BK015_RS15765	COG2911	Protein conserved in bacteria
BK015_RS15770	COG0729	surface antigen
BK015_RS15780	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BK015_RS15805	COG0489	protein tyrosine kinase activity
BK015_RS15810	COG2259	Doxx family
BK015_RS15815	COG1492	cobalamin metabolic process
BK015_RS15825	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BK015_RS15835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BK015_RS15850	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BK015_RS15855	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BK015_RS15860	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BK015_RS15870	COG4206	TonB-dependent receptor
BK015_RS15905	COG0583	DNA-binding transcription factor activity
BK015_RS15920	COG4654	Cytochrome c, class I
BK015_RS15940	COG0795	lipopolysaccharide-transporting ATPase activity
BK015_RS15955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BK015_RS15955	COG1648	precorrin-2 dehydrogenase activity
BK015_RS15960	COG2895	sulfate adenylyltransferase (ATP) activity
BK015_RS15970	COG0175	sulfate reduction
BK015_RS15985	COG0583	DNA-binding transcription factor activity
BK015_RS16000	COG0582	viral genome integration into host DNA
BK015_RS16075	COG1396	sequence-specific DNA binding
BK015_RS16085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BK015_RS16090	COG2258	MOSC domain
BK015_RS16095	COG2267	carboxylic ester hydrolase activity
BK015_RS16105	COG0583	DNA-binding transcription factor activity
BK015_RS16115	COG1187	pseudouridine synthase activity
BK015_RS16130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BK015_RS16130	COG0543	2 iron, 2 sulfur cluster binding
BK015_RS16135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BK015_RS16140	COG0456	acetyltransferase
BK015_RS16180	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BK015_RS16185	COG1047	Peptidyl-prolyl cis-trans
BK015_RS16205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BK015_RS16230	COG1511	domain protein
BK015_RS16230	COG3264	Mechanosensitive ion channel
BK015_RS16235	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BK015_RS16235	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BK015_RS16240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BK015_RS16245	COG0196	riboflavin kinase activity
BK015_RS16250	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BK015_RS16280	COG1113	amino acid transport
BK015_RS16285	COG0542	response to heat
BK015_RS16295	COG1278	Cold shock
BK015_RS16330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BK015_RS16365	COG0656	L-ascorbic acid biosynthetic process
BK015_RS16370	COG2188	Transcriptional regulator
BK015_RS16390	COG2814	Major facilitator Superfamily
BK015_RS16455	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BK015_RS16460	COG1570	exodeoxyribonuclease VII activity
BK015_RS16470	COG1663	tetraacyldisaccharide 4'-kinase activity
BK015_RS16510	COG0728	peptidoglycan biosynthetic process
BK015_RS16530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BK015_RS16535	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BK015_RS16550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BK015_RS16555	COG0318	PFAM AMP-dependent synthetase and ligase
BK015_RS16560	COG4974	Belongs to the 'phage' integrase family
BK015_RS16570	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BK015_RS16575	COG0802	atpase or kinase
BK015_RS16580	COG0860	N-Acetylmuramoyl-L-alanine amidase
BK015_RS16590	COG1741	Belongs to the pirin family
BK015_RS16595	COG3118	belongs to the thioredoxin family
BK015_RS16605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BK015_RS16615	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BK015_RS16630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BK015_RS16640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BK015_RS16645	COG1522	sequence-specific DNA binding
BK015_RS16665	COG2271	Major facilitator Superfamily
BK015_RS16675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BK015_RS16680	COG1012	belongs to the aldehyde dehydrogenase family
BK015_RS16690	COG0583	DNA-binding transcription factor activity
BK015_RS16695	COG0246	Mannitol dehydrogenase
BK015_RS16700	COG1070	Carbohydrate kinase
BK015_RS16705	COG2390	Transcriptional regulator
BK015_RS16720	COG0583	DNA-binding transcription factor activity
BK015_RS16735	COG3842	ATPase activity
BK015_RS16740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BK015_RS16750	COG1175	transmembrane transport
BK015_RS16765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BK015_RS16775	COG0735	belongs to the Fur family
BK015_RS16785	COG1121	(ABC) transporter
BK015_RS16790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BK015_RS16795	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BK015_RS16810	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BK015_RS16815	COG2233	PERMEase
BK015_RS16830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BK015_RS16835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK015_RS16865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BK015_RS16915	COG0009	L-threonylcarbamoyladenylate synthase
BK015_RS16920	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BK015_RS16925	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BK015_RS16930	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BK015_RS16940	COG0469	pyruvate kinase activity
BK015_RS16950	COG0126	phosphoglycerate kinase activity
BK015_RS16985	COG0429	hydrolase of the alpha beta-hydrolase fold
BK015_RS16995	COG4783	chaperone-mediated protein folding
BK015_RS17025	COG3307	-O-antigen
BK015_RS17030	COG4969	Belongs to the N-Me-Phe pilin family
BK015_RS17035	COG0861	Integral membrane protein TerC family
BK015_RS17040	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BK015_RS17055	COG2137	regulation of response to DNA damage stimulus
BK015_RS17060	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BK015_RS17095	COG2801	Transposase and inactivated derivatives
BK015_RS17130	COG5002	protein histidine kinase activity
BK015_RS17130	COG0784	Response regulator, receiver
BK015_RS17135	COG0583	DNA-binding transcription factor activity
BK015_RS17180	COG0028	Belongs to the TPP enzyme family
BK015_RS17185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BK015_RS17190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BK015_RS17275	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BK015_RS17280	COG0583	DNA-binding transcription factor activity
BK015_RS17285	COG1301	dicarboxylic acid transport
BK015_RS17300	COG0840	transmembrane signaling receptor activity
BK015_RS17345	COG4948	Mandelate Racemase Muconate Lactonizing
BK015_RS17375	COG0513	Belongs to the DEAD box helicase family
BK015_RS17420	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BK015_RS17425	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BK015_RS17440	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BK015_RS17445	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BK015_RS17450	COG0367	asparagine synthase
BK015_RS17465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BK015_RS17475	COG1396	sequence-specific DNA binding
BK015_RS17480	COG2814	Major facilitator Superfamily
BK015_RS17485	COG0583	DNA-binding transcription factor activity
BK015_RS17500	COG1702	phosphate starvation-inducible protein PhoH
BK015_RS17515	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BK015_RS17525	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BK015_RS17530	COG0752	glycyl-tRNA synthetase alpha subunit
BK015_RS17535	COG0751	glycine-tRNA ligase activity
BK015_RS17540	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BK015_RS17545	COG0204	Acyl-transferase
BK015_RS17570	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BK015_RS17585	COG3178	'Phosphotransferase
BK015_RS17590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BK015_RS17600	COG5265	(ABC) transporter
BK015_RS17620	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BK015_RS17625	COG1024	Enoyl-CoA hydratase
BK015_RS17630	COG0183	Belongs to the thiolase family
BK015_RS17635	COG1250	3-hydroxyacyl-CoA dehydrogenase
BK015_RS17635	COG1024	Enoyl-CoA hydratase
BK015_RS17640	COG1960	acyl-CoA dehydrogenase activity
BK015_RS17655	COG0494	nUDIX hydrolase
BK015_RS17730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BK015_RS17740	COG0251	oxidation-reduction process
BK015_RS17750	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BK015_RS17775	COG0477	Major facilitator Superfamily
BK015_RS17815	COG1596	polysaccharide export
BK015_RS17820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BK015_RS17840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BK015_RS17850	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BK015_RS17870	COG2204	response regulator
BK015_RS17910	COG5001	Diguanylate cyclase
BK015_RS17910	COG5002	protein histidine kinase activity
BK015_RS17920	COG0235	Class ii aldolase
BK015_RS17980	COG0142	geranyltranstransferase activity
BK015_RS18065	COG0629	single-stranded DNA binding
BK015_RS18070	COG2814	Major facilitator Superfamily
BK015_RS18100	COG1280	lysine exporter protein (LysE YggA)
BK015_RS18125	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BK015_RS18140	COG1137	ATPase activity
BK015_RS18145	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BK015_RS18155	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BK015_RS18180	COG1194	a g-specific adenine glycosylase
BK015_RS18195	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BK015_RS18210	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BK015_RS18230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BK015_RS18245	COG0742	ribosomal rna small subunit methyltransferase
BK015_RS18255	COG0625	glutathione transferase activity
BK015_RS18265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BK015_RS18275	COG0243	molybdopterin cofactor binding
BK015_RS18280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BK015_RS18295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BK015_RS18305	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BK015_RS18310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BK015_RS18325	COG1294	oxidase, subunit
BK015_RS18350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BK015_RS18350	COG2190	(PTS) system
BK015_RS18350	COG1263	PTS System
BK015_RS18355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BK015_RS18355	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK015_RS18360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BK015_RS18365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BK015_RS18370	COG2188	Transcriptional regulator
BK015_RS18380	COG0583	DNA-binding transcription factor activity
BK015_RS18425	COG0318	PFAM AMP-dependent synthetase and ligase
BK015_RS18435	COG1960	acyl-CoA dehydrogenase activity
BK015_RS18445	COG2226	methyltransferase
BK015_RS18455	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BK015_RS18480	COG2814	Major facilitator Superfamily
BK015_RS18490	COG0587	DNA-directed DNA polymerase activity
BK015_RS18505	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BK015_RS18535	COG0840	transmembrane signaling receptor activity
BK015_RS18545	COG1999	signal sequence binding
BK015_RS18555	COG1612	heme a metabolic process
BK015_RS18585	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BK015_RS18595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BK015_RS18610	COG2226	methyltransferase
BK015_RS18615	COG1040	competence protein
BK015_RS18625	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BK015_RS18645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BK015_RS18655	COG0793	Belongs to the peptidase S41A family
BK015_RS18660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BK015_RS18670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BK015_RS18675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK015_RS18685	COG0189	ligase activity
BK015_RS18695	COG0004	ammonium transporteR
BK015_RS18705	COG2960	long-chain fatty acid transporting porin activity
BK015_RS18770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BK015_RS18780	COG4191	Histidine kinase
BK015_RS18790	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BK015_RS18800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BK015_RS18805	COG1960	acyl-CoA dehydrogenase activity
BK015_RS18810	COG1960	acyl-CoA dehydrogenase activity
BK015_RS18815	COG1250	3-hydroxyacyl-CoA dehydrogenase
BK015_RS18815	COG1024	Enoyl-CoA hydratase
BK015_RS18820	COG0583	DNA-binding transcription factor activity
BK015_RS18830	COG0405	Gamma-glutamyltransferase
BK015_RS18855	COG0583	DNA-binding transcription factor activity
BK015_RS18860	COG2921	Belongs to the UPF0250 family
BK015_RS18870	COG1686	Belongs to the peptidase S11 family
BK015_RS18905	COG1127	ABC transporter
BK015_RS18910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BK015_RS18915	COG0737	Belongs to the 5'-nucleotidase family
BK015_RS18930	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BK015_RS18995	COG0582	viral genome integration into host DNA
BK015_RS19000	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BK015_RS19025	COG1024	Enoyl-CoA hydratase
BK015_RS19080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BK015_RS19085	COG0300	oxidoreductase activity
BK015_RS19090	COG1028	Short-chain dehydrogenase reductase Sdr
BK015_RS19110	COG0747	negative chemotaxis
BK015_RS19115	COG0488	(ABC) transporter
BK015_RS19135	COG0288	reversible hydration of carbon dioxide
BK015_RS19140	COG0183	Belongs to the thiolase family
BK015_RS19150	COG3012	SEC-C Motif Domain Protein
BK015_RS19170	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BK015_RS19200	COG1785	Belongs to the alkaline phosphatase family
BK015_RS19210	COG2200	EAL domain
BK015_RS19210	COG2199	diguanylate cyclase activity
BK015_RS19215	COG0025	NhaP-type Na H and K H
BK015_RS19260	COG4650	regulator
BK015_RS19290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BK015_RS19310	COG1999	signal sequence binding
BK015_RS19345	COG3511	phospholipase C
BK015_RS19365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BK015_RS19395	COG0596	Alpha beta hydrolase
BK015_RS19410	COG0583	DNA-binding transcription factor activity
BK015_RS19415	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BK015_RS19435	COG0840	transmembrane signaling receptor activity
BK015_RS19440	COG1609	Transcriptional regulator
BK015_RS19495	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BK015_RS19500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BK015_RS19515	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BK015_RS19520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK015_RS19540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BK015_RS19545	COG1704	LemA family
BK015_RS19665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BK015_RS19680	COG2824	Alkylphosphonate utilization operon protein PhnA
BK015_RS19705	COG0583	DNA-binding transcription factor activity
BK015_RS19715	COG2233	PERMEase
BK015_RS19725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BK015_RS19735	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BK015_RS19745	COG1706	bacterial-type flagellum-dependent cell motility
BK015_RS19750	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BK015_RS19765	COG1749	Flagellar hook protein flgE
BK015_RS19770	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BK015_RS19775	COG1558	bacterial-type flagellum-dependent cell motility
BK015_RS19790	COG2747	anti-sigma28 factor FlgM
BK015_RS19830	COG0741	lytic transglycosylase activity
BK015_RS19835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BK015_RS19845	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BK015_RS19850	COG1984	allophanate hydrolase subunit 2
BK015_RS19885	COG4608	Belongs to the ABC transporter superfamily
BK015_RS19890	COG0444	Belongs to the ABC transporter superfamily
BK015_RS19895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BK015_RS19900	COG0601	transmembrane transport
BK015_RS19905	COG0747	negative chemotaxis
BK015_RS19925	COG0579	oxidoreductase
BK015_RS19945	COG3568	Endonuclease Exonuclease Phosphatase
BK015_RS19950	COG1280	lysine exporter protein (LysE YggA)
BK015_RS19970	COG0531	amino acid
BK015_RS19985	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BK015_RS20045	COG1960	acyl-CoA dehydrogenase activity
BK015_RS20060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BK015_RS20070	COG2814	Major facilitator Superfamily
BK015_RS20090	COG0667	Aldo Keto reductase
BK015_RS20120	COG1560	Kdo2-lipid A biosynthetic process
BK015_RS20135	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BK015_RS20145	COG0523	cobalamin synthesis protein
BK015_RS20175	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BK015_RS20200	COG1309	transcriptional regulator
BK015_RS20215	COG2814	Major facilitator Superfamily
BK015_RS20225	COG2207	Transcriptional regulator
BK015_RS20230	COG1064	alcohol dehydrogenase
BK015_RS20240	COG0708	Exodeoxyribonuclease III
BK015_RS20245	COG2326	polyphosphate kinase activity
BK015_RS20265	COG1077	Cell shape determining protein MreB Mrl
BK015_RS20280	COG0768	penicillin binding
BK015_RS20285	COG0772	Belongs to the SEDS family
BK015_RS20315	COG0720	synthase
BK015_RS20320	COG0602	queuosine metabolic process
BK015_RS20350	COG4695	Portal protein
BK015_RS20585	COG0582	viral genome integration into host DNA
BK015_RS20595	COG2204	response regulator
BK015_RS20600	COG5000	phosphorelay sensor kinase activity
BK015_RS20635	COG0242	peptide deformylase activity
BK015_RS20640	COG0758	DNA mediated transformation
BK015_RS20655	COG0583	DNA-binding transcription factor activity
BK015_RS20660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BK015_RS20690	COG4974	Belongs to the 'phage' integrase family
BK015_RS20715	COG3436	PFAM IS66 Orf2 family protein
BK015_RS20720	COG4372	Transposase
BK015_RS20725	COG3012	SEC-C Motif Domain Protein
BK015_RS20745	COG4695	Portal protein
BK015_RS20750	COG3012	SEC-C Motif Domain Protein
BK015_RS20755	COG4372	Transposase
BK015_RS20760	COG3436	PFAM IS66 Orf2 family protein
BK015_RS20780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BK015_RS20795	COG0583	DNA-binding transcription factor activity
BK015_RS20825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BK015_RS20840	COG2169	Transcriptional regulator
BK015_RS20840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BK015_RS20870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BK015_RS20955	COG0582	viral genome integration into host DNA
BK015_RS21175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BK015_RS21525	COG0356	it plays a direct role in the translocation of protons across the membrane
BK015_RS21755	COG0531	amino acid
BK015_RS21775	COG1012	belongs to the aldehyde dehydrogenase family
BK015_RS21980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BK015_RS22090	COG1360	Flagellar Motor Protein
BK015_RS22350	COG0281	malic enzyme
BK015_RS22350	COG0280	phosphate acetyltransferase
BK015_RS22970	COG0842	Transport permease protein
BK015_RS23545	COG0318	PFAM AMP-dependent synthetase and ligase
BK015_RS23580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BK015_RS23595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BK015_RS23865	COG0439	Biotin carboxylase
BK015_RS23955	COG1028	Short-chain dehydrogenase reductase Sdr
BK015_RS24380	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BK015_RS24390	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BK015_RS24570	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BK015_RS24580	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BK015_RS24660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BK015_RS25355	COG1086	Polysaccharide biosynthesis protein
BK015_RS26115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BK015_RS26155	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BK015_RS26845	COG0303	'Molybdopterin
BK015_RS27115	COG0683	leucine binding
BK015_RS27360	COG0822	iron-sulfur transferase activity
BK015_RS27885	COG2223	nitrite transmembrane transporter activity
BK015_RS27960	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BK015_RS27985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BK015_RS28110	COG0084	hydrolase, TatD family'
BK015_RS28330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BK015_RS28625	COG0351	phosphomethylpyrimidine kinase
BK015_RS28780	COG0750	zinc metalloprotease
BK015_RS29305	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BK015_RS29305	COG0047	phosphoribosylformylglycinamidine synthase activity
BK015_RS29375	COG1335	isochorismatase
BK015_RS29385	COG0183	Belongs to the thiolase family
BK015_RS29390	COG0183	Belongs to the thiolase family
BK015_RS29785	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BK015_RS30020	COG2070	2-Nitropropane dioxygenase
BK015_RS30250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BK015_RS31015	COG2235	arginine
BK015_RS31090	COG1649	PFAM Uncharacterised BCR, COG1649
BK015_RS31260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BK015_RS31270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BK015_RS31595	COG2718	Belongs to the UPF0229 family
BK015_RS32070	COG4964	Belongs to the GSP D family
BK015_RS32490	COG1538	Outer membrane efflux protein
BK015_RS32540	COG0210	DNA helicase
BK015_RS32550	COG0525	valine-tRNA ligase activity
BK015_RS32645	COG3962	Belongs to the TPP enzyme family
BK015_RS32655	COG3718	enzyme involved in inositol metabolism
BK015_RS32735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BK015_RS32975	COG1914	H( )-stimulated, divalent metal cation uptake system
BK015_RS33285	COG0366	Alpha amylase catalytic
BK015_RS33435	COG0582	viral genome integration into host DNA
BK015_RS33600	COG0248	Ppx GppA phosphatase
BK015_RS34085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BK015_RS34115	COG1074	ATP-dependent DNA helicase activity
BK015_RS34125	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BK015_RS34360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BK015_RS34555	COG1007	ATP synthesis coupled electron transport
BK015_RS35175	COG1674	ftsk spoiiie
BK015_RS35195	COG3387	PFAM Glycoside hydrolase 15-related
BK015_RS35225	COG2878	Part of a membrane complex involved in electron transport
BK015_RS36170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BK015_RS36575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BK015_RS36585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BK015_RS36635	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BK015_RS36835	COG2814	Major facilitator Superfamily