locus-tag	class	description
AQ475_RS00010	COG0592	DNA-directed DNA polymerase activity
AQ475_RS00025	COG0753	catalase activity
AQ475_RS00060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AQ475_RS00070	COG1024	Enoyl-CoA hydratase
AQ475_RS00070	COG1250	3-hydroxyacyl-CoA dehydrogenase
AQ475_RS00075	COG0183	Belongs to the thiolase family
AQ475_RS00085	COG1960	acyl-CoA dehydrogenase activity
AQ475_RS00110	COG1695	Transcriptional regulator
AQ475_RS00170	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AQ475_RS00185	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AQ475_RS00200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AQ475_RS00210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AQ475_RS00215	COG2226	methyltransferase
AQ475_RS00220	COG0789	Transcriptional regulator
AQ475_RS00230	COG1987	bacterial-type flagellum assembly
AQ475_RS00235	COG1338	Plays a role in the flagellum-specific transport system
AQ475_RS00245	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AQ475_RS00260	COG1346	cytolysis
AQ475_RS00270	COG0583	DNA-binding transcription factor activity
AQ475_RS00275	COG2814	Major facilitator Superfamily
AQ475_RS00280	COG1846	Transcriptional regulator
AQ475_RS00325	COG2165	general secretion pathway protein
AQ475_RS00360	COG0523	cobalamin synthesis protein
AQ475_RS00390	COG0519	Catalyzes the synthesis of GMP from XMP
AQ475_RS00390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AQ475_RS00395	COG1902	pentaerythritol trinitrate reductase activity
AQ475_RS00410	COG0642	Histidine kinase
AQ475_RS00430	COG3186	Phenylalanine-4-hydroxylase
AQ475_RS00435	COG1522	sequence-specific DNA binding
AQ475_RS00445	COG0583	DNA-binding transcription factor activity
AQ475_RS00455	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AQ475_RS00520	COG1192	Involved in chromosome partitioning
AQ475_RS00525	COG1475	DNA binding
AQ475_RS00530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AQ475_RS00540	COG0356	it plays a direct role in the translocation of protons across the membrane
AQ475_RS00580	COG0318	PFAM AMP-dependent synthetase and ligase
AQ475_RS00595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AQ475_RS00605	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AQ475_RS00605	COG0506	proline dehydrogenase activity
AQ475_RS00605	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AQ475_RS00610	COG0683	leucine binding
AQ475_RS00620	COG1960	acyl-CoA dehydrogenase activity
AQ475_RS00630	COG0436	Aminotransferase
AQ475_RS00650	COG0789	Transcriptional regulator
AQ475_RS00670	COG0668	transmembrane transport
AQ475_RS00680	COG0531	amino acid
AQ475_RS00685	COG4303	Ethanolamine ammonia lyase large subunit
AQ475_RS00690	COG4302	ethanolamine ammonia-lyase activity
AQ475_RS00695	COG0583	DNA-binding transcription factor activity
AQ475_RS00705	COG1012	belongs to the aldehyde dehydrogenase family
AQ475_RS00710	COG2207	Transcriptional regulator
AQ475_RS00725	COG1760	l-serine dehydratase
AQ475_RS00745	COG0509	glycine decarboxylation via glycine cleavage system
AQ475_RS00760	COG0673	inositol 2-dehydrogenase activity
AQ475_RS00775	COG0210	DNA helicase
AQ475_RS00790	COG0582	viral genome integration into host DNA
AQ475_RS00805	COG3397	chitin binding
AQ475_RS00865	COG0596	Alpha beta hydrolase
AQ475_RS00935	COG2818	Glycosylase
AQ475_RS00950	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AQ475_RS00955	COG2916	Histone family protein nucleoid-structuring protein H-NS
AQ475_RS00960	COG0438	transferase activity, transferring glycosyl groups
AQ475_RS01000	COG0835	chemotaxis
AQ475_RS01010	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AQ475_RS01025	COG0745	RESPONSE REGULATOR receiver
AQ475_RS01030	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AQ475_RS01055	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AQ475_RS01060	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AQ475_RS01070	COG2894	cell division
AQ475_RS01085	COG1950	PFAM Membrane protein of
AQ475_RS01090	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AQ475_RS01105	COG2070	2-Nitropropane dioxygenase
AQ475_RS01130	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AQ475_RS01135	COG1522	sequence-specific DNA binding
AQ475_RS01145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AQ475_RS01165	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AQ475_RS01170	COG2823	Periplasmic or secreted lipoprotein
AQ475_RS01175	COG4654	Cytochrome c, class I
AQ475_RS01185	COG1113	amino acid transport
AQ475_RS01215	COG2084	Dehydrogenase
AQ475_RS01220	COG1280	lysine exporter protein (LysE YggA)
AQ475_RS01225	COG2814	Major facilitator Superfamily
AQ475_RS01230	COG0583	DNA-binding transcription factor activity
AQ475_RS01255	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AQ475_RS01265	COG1881	PFAM PEBP family protein
AQ475_RS01270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AQ475_RS01275	COG0281	malic enzyme
AQ475_RS01275	COG0280	phosphate acetyltransferase
AQ475_RS01295	COG1522	sequence-specific DNA binding
AQ475_RS01315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AQ475_RS01320	COG2151	metal-sulfur cluster biosynthetic enzyme
AQ475_RS01325	COG3396	Phenylacetate-CoA oxygenase
AQ475_RS01330	COG3460	Phenylacetate-CoA oxygenase
AQ475_RS01335	COG3396	Phenylacetate-CoA oxygenase
AQ475_RS01375	COG3436	PFAM IS66 Orf2 family protein
AQ475_RS01405	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AQ475_RS01445	COG0514	ATP-dependent DNA helicase (RecQ)
AQ475_RS01575	COG0201	protein transport
AQ475_RS01620	COG4232	protein-disulfide reductase activity
AQ475_RS01640	COG1333	cytochrome c biogenesis protein
AQ475_RS01645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AQ475_RS01650	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AQ475_RS01655	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AQ475_RS01710	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AQ475_RS01725	COG0395	ABC-type sugar transport system, permease component
AQ475_RS01735	COG0584	glycerophosphoryl diester phosphodiesterase
AQ475_RS01750	COG0069	glutamate synthase activity
AQ475_RS01750	COG0070	glutamate synthase
AQ475_RS01750	COG0067	glutamate synthase
AQ475_RS01760	COG1115	amino acid carrier protein
AQ475_RS01775	COG4178	(ABC) transporter
AQ475_RS01800	COG1127	ABC transporter
AQ475_RS01805	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AQ475_RS01810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AQ475_RS01830	COG1131	(ABC) transporter
AQ475_RS01835	COG0842	Transport permease protein
AQ475_RS01860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AQ475_RS01870	COG2095	MarC family integral membrane protein
AQ475_RS01920	COG0805	protein transport
AQ475_RS01925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AQ475_RS01930	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AQ475_RS01935	COG0723	plastoquinol--plastocyanin reductase activity
AQ475_RS01940	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AQ475_RS01945	COG2857	Cytochrome c1
AQ475_RS01950	COG0625	glutathione transferase activity
AQ475_RS01955	COG2969	positive regulation of protein catabolic process
AQ475_RS01965	COG0582	viral genome integration into host DNA
AQ475_RS02025	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AQ475_RS02040	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AQ475_RS02055	COG4372	Transposase
AQ475_RS02060	COG3436	PFAM IS66 Orf2 family protein
AQ475_RS02175	COG0308	aminopeptidase N
AQ475_RS02220	COG0443	Heat shock 70 kDa protein
AQ475_RS02225	COG1278	Cold shock
AQ475_RS02230	COG0531	amino acid
AQ475_RS02235	COG3384	dioxygenase
AQ475_RS02245	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AQ475_RS02250	COG2890	protein-(glutamine-N5) methyltransferase activity
AQ475_RS02270	COG0006	proline dipeptidase activity
AQ475_RS02275	COG1335	isochorismatase
AQ475_RS02285	COG0488	(ABC) transporter
AQ475_RS02305	COG0012	GTP binding
AQ475_RS02320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AQ475_RS02325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AQ475_RS02340	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AQ475_RS02360	COG0512	Glutamine amidotransferase of anthranilate synthase
AQ475_RS02370	COG0546	phosphoglycolate phosphatase activity
AQ475_RS02375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AQ475_RS02380	COG2967	ApaG domain
AQ475_RS02385	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AQ475_RS02395	COG2050	protein possibly involved in aromatic compounds catabolism
AQ475_RS02400	COG1024	Enoyl-CoA hydratase
AQ475_RS02405	COG0183	Belongs to the thiolase family
AQ475_RS02415	COG1024	Enoyl-CoA hydratase
AQ475_RS02445	COG0243	molybdopterin cofactor binding
AQ475_RS02450	COG0318	PFAM AMP-dependent synthetase and ligase
AQ475_RS02455	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AQ475_RS02475	COG3116	cell division
AQ475_RS02485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AQ475_RS02490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AQ475_RS02525	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AQ475_RS02540	COG0678	peroxiredoxin activity
AQ475_RS02575	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AQ475_RS02590	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AQ475_RS02600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AQ475_RS02605	COG4536	flavin adenine dinucleotide binding
AQ475_RS02660	COG3436	PFAM IS66 Orf2 family protein
AQ475_RS02665	COG4372	Transposase
AQ475_RS02680	COG3012	SEC-C Motif Domain Protein
AQ475_RS02725	COG0582	viral genome integration into host DNA
AQ475_RS02735	COG0142	geranyltranstransferase activity
AQ475_RS02780	COG2095	MarC family integral membrane protein
AQ475_RS02785	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AQ475_RS02790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AQ475_RS02810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AQ475_RS02810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AQ475_RS02830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AQ475_RS02835	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AQ475_RS02850	COG0439	Biotin carboxylase
AQ475_RS02855	COG0511	ligase activity, forming carbon-carbon bonds
AQ475_RS02860	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AQ475_RS02865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AQ475_RS02875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AQ475_RS02880	COG3150	esterase
AQ475_RS02885	COG0557	exoribonuclease II activity
AQ475_RS02890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AQ475_RS02910	COG1414	Transcriptional regulator
AQ475_RS02915	COG3734	2-keto-3-deoxy-galactonokinase
AQ475_RS02920	COG0800	Aldolase
AQ475_RS02925	COG1028	Short-chain dehydrogenase reductase Sdr
AQ475_RS02940	COG1172	Belongs to the binding-protein-dependent transport system permease family
AQ475_RS02945	COG1028	Short-chain dehydrogenase reductase Sdr
AQ475_RS02955	COG0284	orotidine-5'-phosphate decarboxylase activity
AQ475_RS02960	COG1546	Belongs to the CinA family
AQ475_RS02965	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AQ475_RS02995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AQ475_RS03005	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AQ475_RS03010	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AQ475_RS03015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AQ475_RS03020	COG2814	Major facilitator Superfamily
AQ475_RS03035	COG0583	DNA-binding transcription factor activity
AQ475_RS03045	COG1301	dicarboxylic acid transport
AQ475_RS03050	COG4266	Belongs to the allantoicase family
AQ475_RS03055	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AQ475_RS03060	COG0735	belongs to the Fur family
AQ475_RS03065	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AQ475_RS03090	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AQ475_RS03095	COG1466	dna polymerase III delta subunit
AQ475_RS03105	COG1981	membrane
AQ475_RS03110	COG1737	Transcriptional regulator
AQ475_RS03110	COG0837	glucose binding
AQ475_RS03120	COG0800	Aldolase
AQ475_RS03140	COG2223	nitrite transmembrane transporter activity
AQ475_RS03145	COG0583	DNA-binding transcription factor activity
AQ475_RS03150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AQ475_RS03155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AQ475_RS03160	COG0765	amino acid transport
AQ475_RS03165	COG0765	amino acid transport
AQ475_RS03170	COG1126	abc transporter atp-binding protein
AQ475_RS03175	COG0121	glutamine amidotransferase
AQ475_RS03180	COG0418	dihydroorotase activity
AQ475_RS03215	COG1917	Cupin 2, conserved barrel domain protein
AQ475_RS03215	COG4977	sequence-specific DNA binding
AQ475_RS03220	COG0625	glutathione transferase activity
AQ475_RS03225	COG0625	glutathione transferase activity
AQ475_RS03245	COG0588	phosphoglycerate mutase activity
AQ475_RS03285	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AQ475_RS03290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AQ475_RS03295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AQ475_RS03300	COG0006	proline dipeptidase activity
AQ475_RS03305	COG0625	glutathione transferase activity
AQ475_RS03315	COG0069	glutamate synthase activity
AQ475_RS03370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AQ475_RS03370	COG3008	intermembrane lipid transfer
AQ475_RS03375	COG2995	paraquat-inducible protein a
AQ475_RS03390	COG3038	cytochrome b561
AQ475_RS03395	COG2353	YceI-like domain
AQ475_RS03400	COG2353	YceI-like domain
AQ475_RS03410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AQ475_RS03415	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AQ475_RS03420	COG1862	Preprotein translocase
AQ475_RS03425	COG0343	queuine tRNA-ribosyltransferase activity
AQ475_RS03435	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AQ475_RS03455	COG0783	Belongs to the Dps family
AQ475_RS03485	COG0247	lactate metabolic process
AQ475_RS03490	COG0277	FAD linked oxidase domain protein
AQ475_RS03495	COG0277	FAD linked oxidase domain protein
AQ475_RS03500	COG0277	FAD linked oxidase domain protein
AQ475_RS03505	COG2096	Adenosyltransferase
AQ475_RS03510	COG1017	nitric oxide dioxygenase activity
AQ475_RS03510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AQ475_RS03515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AQ475_RS03520	COG0312	modulator of DNA gyrase
AQ475_RS03525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AQ475_RS03530	COG3164	Protein of unknown function
AQ475_RS03535	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AQ475_RS03540	COG0497	DNA recombination
AQ475_RS03585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AQ475_RS03595	COG1428	Deoxynucleoside kinase
AQ475_RS03600	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AQ475_RS03605	COG0617	tRNA 3'-terminal CCA addition
AQ475_RS03615	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AQ475_RS03640	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AQ475_RS03645	COG0586	Pfam SNARE associated Golgi protein
AQ475_RS03695	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AQ475_RS03735	COG1028	Short-chain dehydrogenase reductase Sdr
AQ475_RS03740	COG1368	sulfuric ester hydrolase activity
AQ475_RS03745	COG3321	synthase
AQ475_RS03745	COG1028	Short-chain dehydrogenase reductase Sdr
AQ475_RS03745	COG0604	alcohol dehydrogenase
AQ475_RS03750	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AQ475_RS03755	COG0156	8-amino-7-oxononanoate synthase activity
AQ475_RS03805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AQ475_RS03810	COG0489	protein tyrosine kinase activity
AQ475_RS03810	COG3206	protein involved in exopolysaccharide biosynthesis
AQ475_RS03820	COG3562	capsule polysaccharide
AQ475_RS03825	COG1045	serine acetyltransferase
AQ475_RS03840	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AQ475_RS03845	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AQ475_RS03850	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AQ475_RS03850	COG0517	IMP dehydrogenase activity
AQ475_RS03880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AQ475_RS03925	COG0824	Thioesterase
AQ475_RS03930	COG4221	oxidoreductase activity
AQ475_RS03985	COG0450	alkyl hydroperoxide reductase
AQ475_RS03990	COG1960	acyl-CoA dehydrogenase activity
AQ475_RS04025	COG2814	Major facilitator Superfamily
AQ475_RS04045	COG2814	Major facilitator Superfamily
AQ475_RS04050	COG0778	Nitroreductase
AQ475_RS04055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AQ475_RS04060	COG0583	DNA-binding transcription factor activity
AQ475_RS04065	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AQ475_RS04090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AQ475_RS04105	COG4774	siderophore transport
AQ475_RS04110	COG1120	ATPase activity
AQ475_RS04120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AQ475_RS04160	COG0730	response to heat
AQ475_RS04175	COG1280	lysine exporter protein (LysE YggA)
AQ475_RS04225	COG0604	alcohol dehydrogenase
AQ475_RS04230	COG1733	regulation of RNA biosynthetic process
AQ475_RS04240	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AQ475_RS04255	COG1773	rubredoxin
AQ475_RS04275	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AQ475_RS04350	COG1215	transferase activity, transferring glycosyl groups
AQ475_RS04365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AQ475_RS04380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AQ475_RS04405	COG0859	PFAM glycosyl transferase family 9
AQ475_RS04460	COG1129	ABC transporter
AQ475_RS04485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AQ475_RS04495	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AQ475_RS04505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AQ475_RS04545	COG2801	Transposase and inactivated derivatives
AQ475_RS04570	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AQ475_RS04590	COG0762	integral membrane protein
AQ475_RS04630	COG0436	Aminotransferase
AQ475_RS04655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AQ475_RS04655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AQ475_RS04675	COG2814	Major facilitator Superfamily
AQ475_RS04680	COG1126	abc transporter atp-binding protein
AQ475_RS04685	COG0765	amino acid transport
AQ475_RS04690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AQ475_RS04705	COG0363	glucosamine-6-phosphate deaminase activity
AQ475_RS04710	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AQ475_RS04720	COG1175	transmembrane transport
AQ475_RS04725	COG0395	ABC-type sugar transport system, permease component
AQ475_RS04730	COG3842	ATPase activity
AQ475_RS04735	COG2860	membrane
AQ475_RS04740	COG1193	negative regulation of DNA recombination
AQ475_RS04745	COG0492	ferredoxin-NADP+ reductase activity
AQ475_RS04750	COG1674	ftsk spoiiie
AQ475_RS04755	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AQ475_RS04760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AQ475_RS04795	COG2894	cell division
AQ475_RS04815	COG0859	PFAM glycosyl transferase family 9
AQ475_RS04825	COG0477	Major facilitator Superfamily
AQ475_RS04855	COG3328	transposase activity
AQ475_RS04875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AQ475_RS04880	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AQ475_RS04890	COG1561	YicC-like family, N-terminal region
AQ475_RS04905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AQ475_RS04925	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AQ475_RS04935	COG1278	Cold shock
AQ475_RS04940	COG2176	DNA-directed DNA polymerase activity
AQ475_RS04955	COG4772	TonB-dependent receptor
AQ475_RS04990	COG0583	DNA-binding transcription factor activity
AQ475_RS05005	COG0308	aminopeptidase N
AQ475_RS05015	COG2119	membrane
AQ475_RS05020	COG0402	S-adenosylhomocysteine deaminase activity
AQ475_RS05025	COG2252	PERMEase
AQ475_RS05030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AQ475_RS05055	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AQ475_RS05085	COG3383	formate dehydrogenase (NAD+) activity
AQ475_RS05100	COG1910	domain protein
AQ475_RS05110	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AQ475_RS05180	COG0582	viral genome integration into host DNA
AQ475_RS05190	COG0546	phosphoglycolate phosphatase activity
AQ475_RS05215	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AQ475_RS05220	COG1605	Chorismate mutase
AQ475_RS05220	COG0077	Prephenate dehydratase
AQ475_RS05225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AQ475_RS05250	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AQ475_RS05260	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AQ475_RS05285	COG2951	lytic endotransglycosylase activity
AQ475_RS05290	COG0123	including yeast histone deacetylase and acetoin utilization protein
AQ475_RS05295	COG2267	carboxylic ester hydrolase activity
AQ475_RS05305	COG2011	ABC-type metal ion transport system permease component
AQ475_RS05310	COG1464	Belongs to the NlpA lipoprotein family
AQ475_RS05325	COG1960	acyl-CoA dehydrogenase activity
AQ475_RS05400	COG0501	Belongs to the peptidase M48B family
AQ475_RS05410	COG0521	Mo-molybdopterin cofactor biosynthetic process
AQ475_RS05415	COG3028	Belongs to the UPF0307 family
AQ475_RS05420	COG0312	modulator of DNA gyrase
AQ475_RS05425	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AQ475_RS05455	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AQ475_RS05465	COG0640	Transcriptional regulator
AQ475_RS05485	COG0114	fumarate hydratase activity
AQ475_RS05490	COG0534	Mate efflux family protein
AQ475_RS05495	COG2501	S4 domain
AQ475_RS05515	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AQ475_RS05530	COG3045	CreA protein
AQ475_RS05545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AQ475_RS05550	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AQ475_RS05595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AQ475_RS05600	COG1530	ribonuclease E activity
AQ475_RS05610	COG0546	phosphoglycolate phosphatase activity
AQ475_RS05635	COG1399	metal-binding, possibly nucleic acid-binding protein
AQ475_RS05670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AQ475_RS05690	COG3026	antisigma factor binding
AQ475_RS05695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AQ475_RS05710	COG0681	Belongs to the peptidase S26 family
AQ475_RS05715	COG0571	ribonuclease III activity
AQ475_RS05720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AQ475_RS05730	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AQ475_RS05745	COG2204	response regulator
AQ475_RS05765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AQ475_RS05785	COG1956	GAF domain-containing protein
AQ475_RS05790	COG0583	DNA-binding transcription factor activity
AQ475_RS05800	COG2153	protein acetylation
AQ475_RS05825	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AQ475_RS05830	COG1132	(ABC) transporter
AQ475_RS05835	COG0438	transferase activity, transferring glycosyl groups
AQ475_RS05850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AQ475_RS05855	COG0683	leucine binding
AQ475_RS05860	COG3511	phospholipase C
AQ475_RS05870	COG0596	Alpha beta hydrolase
AQ475_RS05875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AQ475_RS05890	COG3394	polysaccharide catabolic process
AQ475_RS05925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AQ475_RS05955	COG0625	glutathione transferase activity
AQ475_RS05965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AQ475_RS05975	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AQ475_RS06000	COG1959	2 iron, 2 sulfur cluster binding
AQ475_RS06010	COG2151	metal-sulfur cluster biosynthetic enzyme
AQ475_RS06015	COG0822	iron-sulfur transferase activity
AQ475_RS06020	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AQ475_RS06030	COG0396	ATPase activity
AQ475_RS06035	COG0719	Fe-S assembly protein
AQ475_RS06045	COG0840	transmembrane signaling receptor activity
AQ475_RS06050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AQ475_RS06055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AQ475_RS06070	COG0826	peptidase U32
AQ475_RS06075	COG0826	peptidase U32
AQ475_RS06080	COG3154	lipid carrier protein
AQ475_RS06115	COG2151	metal-sulfur cluster biosynthetic enzyme
AQ475_RS06130	COG0415	Belongs to the DNA photolyase family
AQ475_RS06135	COG0529	Catalyzes the synthesis of activated sulfate
AQ475_RS06175	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AQ475_RS06190	COG0402	S-adenosylhomocysteine deaminase activity
AQ475_RS06205	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AQ475_RS06210	COG0174	glutamine synthetase
AQ475_RS06275	COG0582	viral genome integration into host DNA
AQ475_RS06285	COG0583	DNA-binding transcription factor activity
AQ475_RS06290	COG1960	acyl-CoA dehydrogenase activity
AQ475_RS06300	COG0477	Major facilitator Superfamily
AQ475_RS06310	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AQ475_RS06310	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AQ475_RS06315	COG1643	Atp-dependent helicase
AQ475_RS06335	COG1058	Belongs to the CinA family
AQ475_RS06335	COG1546	Belongs to the CinA family
AQ475_RS06345	COG0174	glutamine synthetase
AQ475_RS06380	COG2197	response regulator
AQ475_RS06385	COG4585	Histidine kinase
AQ475_RS06390	COG2181	nitrate reductase activity
AQ475_RS06395	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AQ475_RS06400	COG1140	nitrate reductase beta subunit
AQ475_RS06405	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AQ475_RS06410	COG2223	nitrite transmembrane transporter activity
AQ475_RS06425	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AQ475_RS06430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AQ475_RS06435	COG0339	signal peptide processing
AQ475_RS06445	COG4566	intracellular signal transduction
AQ475_RS06455	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AQ475_RS06460	COG0508	dehydrogenase complex catalyzes the overall conversion of
AQ475_RS06465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AQ475_RS06480	COG1414	Transcriptional regulator
AQ475_RS06485	COG0247	lactate metabolic process
AQ475_RS06500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AQ475_RS06510	COG1104	cysteine desulfurase activity
AQ475_RS06515	COG0822	iron-sulfur transferase activity
AQ475_RS06520	COG0316	Belongs to the HesB IscA family
AQ475_RS06540	COG2975	iron-sulfur cluster assembly
AQ475_RS06570	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AQ475_RS06590	COG0084	hydrolase, TatD family'
AQ475_RS06595	COG2333	competence protein COMEC
AQ475_RS06595	COG0658	competence protein
AQ475_RS06600	COG2267	carboxylic ester hydrolase activity
AQ475_RS06625	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AQ475_RS06635	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AQ475_RS06645	COG2833	Protein of unknown function (DUF455)
AQ475_RS06650	COG0596	Alpha beta hydrolase
AQ475_RS06655	COG0613	PHP domain protein
AQ475_RS06660	COG0009	L-threonylcarbamoyladenylate synthase
AQ475_RS06665	COG1994	Peptidase M50
AQ475_RS06670	COG0180	Tryptophanyl-tRNA synthetase
AQ475_RS06680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AQ475_RS06685	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AQ475_RS06690	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AQ475_RS06695	COG2850	peptidyl-arginine hydroxylation
AQ475_RS06720	COG0483	inositol monophosphate 1-phosphatase activity
AQ475_RS06730	COG1045	serine acetyltransferase
AQ475_RS06740	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AQ475_RS06750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AQ475_RS06775	COG0037	tRNA processing
AQ475_RS06780	COG0527	aspartate kinase activity
AQ475_RS06805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AQ475_RS06810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AQ475_RS06815	COG0529	Catalyzes the synthesis of activated sulfate
AQ475_RS06815	COG2895	sulfate adenylyltransferase (ATP) activity
AQ475_RS06845	COG2175	clavaminate synthase activity
AQ475_RS06865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AQ475_RS06870	COG3958	Transketolase
AQ475_RS06885	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AQ475_RS06900	COG2895	sulfate adenylyltransferase (ATP) activity
AQ475_RS06905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AQ475_RS06920	COG0024	Methionine aminopeptidase
AQ475_RS06930	COG0243	molybdopterin cofactor binding
AQ475_RS06950	COG4174	ABC transporter (Permease)
AQ475_RS06955	COG4239	(ABC) transporter, permease
AQ475_RS06960	COG4172	Belongs to the ABC transporter superfamily
AQ475_RS06965	COG0791	NLP P60 protein
AQ475_RS06970	COG1752	Esterase of the alpha-beta hydrolase superfamily
AQ475_RS07025	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AQ475_RS07035	COG0583	DNA-binding transcription factor activity
AQ475_RS07045	COG2224	Isocitrate lyase
AQ475_RS07050	COG0513	Belongs to the DEAD box helicase family
AQ475_RS07060	COG1214	PFAM Peptidase M22, glycoprotease
AQ475_RS07070	COG1573	uracil-dna glycosylase
AQ475_RS07080	COG0351	phosphomethylpyrimidine kinase
AQ475_RS07085	COG0477	Major facilitator Superfamily
AQ475_RS07105	COG0488	(ABC) transporter
AQ475_RS07110	COG0386	Belongs to the glutathione peroxidase family
AQ475_RS07120	COG2890	protein-(glutamine-N5) methyltransferase activity
AQ475_RS07130	COG1393	Belongs to the ArsC family
AQ475_RS07170	COG0242	peptide deformylase activity
AQ475_RS07175	COG1187	pseudouridine synthase activity
AQ475_RS07185	COG0024	Methionine aminopeptidase
AQ475_RS07210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AQ475_RS07225	COG0750	zinc metalloprotease
AQ475_RS07265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AQ475_RS07295	COG0330	HflC and HflK could
AQ475_RS07315	COG0697	spore germination
AQ475_RS07370	COG1619	proteins homologs of microcin C7 resistance protein MccF
AQ475_RS07380	COG1953	Uracil, thiamine, allantoin
AQ475_RS07395	COG3648	Uricase
AQ475_RS07395	COG3195	allantoin biosynthetic process
AQ475_RS07400	COG4266	Belongs to the allantoicase family
AQ475_RS07435	COG3360	Dodecin
AQ475_RS07495	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AQ475_RS07510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AQ475_RS07610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AQ475_RS07615	COG1846	Transcriptional regulator
AQ475_RS07640	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AQ475_RS07675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AQ475_RS07685	COG4181	ATPase activity
AQ475_RS07700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AQ475_RS07710	COG0047	phosphoribosylformylglycinamidine synthase activity
AQ475_RS07710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AQ475_RS07720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AQ475_RS07745	COG0318	PFAM AMP-dependent synthetase and ligase
AQ475_RS07750	COG1250	3-hydroxyacyl-CoA dehydrogenase
AQ475_RS07750	COG1024	Enoyl-CoA hydratase
AQ475_RS07755	COG1335	isochorismatase
AQ475_RS07760	COG0183	Belongs to the thiolase family
AQ475_RS07785	COG2130	NADP-dependent
AQ475_RS07790	COG0657	acetylesterase activity
AQ475_RS07795	COG2153	protein acetylation
AQ475_RS07805	COG0354	folic acid binding
AQ475_RS07810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AQ475_RS07825	COG1247	-acetyltransferase
AQ475_RS07830	COG0084	hydrolase, TatD family'
AQ475_RS07855	COG0438	transferase activity, transferring glycosyl groups
AQ475_RS07875	COG0252	asparaginase activity
AQ475_RS07880	COG1652	LysM domain
AQ475_RS07890	COG2084	Dehydrogenase
AQ475_RS07895	COG3622	Belongs to the hyi family
AQ475_RS07900	COG3960	tartronate-semialdehyde synthase activity
AQ475_RS07905	COG0583	DNA-binding transcription factor activity
AQ475_RS07960	COG0306	phosphate transporter
AQ475_RS07965	COG0791	NLP P60 protein
AQ475_RS07970	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AQ475_RS07975	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AQ475_RS07980	COG0726	polysaccharide deacetylase
AQ475_RS07985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AQ475_RS07985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AQ475_RS07995	COG0463	Glycosyl transferase, family 2
AQ475_RS08000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AQ475_RS08005	COG2076	Multidrug Resistance protein
AQ475_RS08010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AQ475_RS08020	COG0436	Aminotransferase
AQ475_RS08040	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AQ475_RS08045	COG0314	molybdopterin synthase activity
AQ475_RS08050	COG2346	COG2346, Truncated hemoglobins
AQ475_RS08055	COG1959	2 iron, 2 sulfur cluster binding
AQ475_RS08060	COG0542	response to heat
AQ475_RS08090	COG0534	Mate efflux family protein
AQ475_RS08105	COG3228	Belongs to the MtfA family
AQ475_RS08115	COG0789	Transcriptional regulator
AQ475_RS08125	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AQ475_RS08145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AQ475_RS08160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AQ475_RS08200	COG0670	Belongs to the BI1 family
AQ475_RS08235	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AQ475_RS08250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AQ475_RS08255	COG0330	HflC and HflK could
AQ475_RS08260	COG0330	HflC and HflK could
AQ475_RS08265	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AQ475_RS08280	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AQ475_RS08290	COG2183	response to ionizing radiation
AQ475_RS08305	COG1199	ATP-dependent helicase activity
AQ475_RS08315	COG0564	pseudouridine synthase activity
AQ475_RS08320	COG1496	oxidoreductase activity
AQ475_RS08325	COG3243	poly(R)-hydroxyalkanoic acid synthase
AQ475_RS08330	COG0183	Belongs to the thiolase family
AQ475_RS08335	COG1028	Short-chain dehydrogenase reductase Sdr
AQ475_RS08355	COG0183	Belongs to the thiolase family
AQ475_RS08365	COG0626	cystathionine gamma-synthase activity
AQ475_RS08370	COG0560	Phosphoserine phosphatase
AQ475_RS08385	COG0390	transport system, permease component
AQ475_RS08390	COG1122	ATPase activity
AQ475_RS08395	COG2982	Protein involved in outer membrane biogenesis
AQ475_RS08400	COG0488	(ABC) transporter
AQ475_RS08415	COG2070	2-Nitropropane dioxygenase
AQ475_RS08420	COG3047	cAMP biosynthetic process
AQ475_RS08430	COG1914	H( )-stimulated, divalent metal cation uptake system
AQ475_RS08435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AQ475_RS08440	COG3842	ATPase activity
AQ475_RS08445	COG1176	ABC-type spermidine putrescine transport system, permease component I
AQ475_RS08450	COG1177	transmembrane transport
AQ475_RS08480	COG3655	Transcriptional regulator
AQ475_RS08490	COG1538	Outer membrane efflux protein
AQ475_RS08495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AQ475_RS08505	COG1309	transcriptional regulator
AQ475_RS08510	COG0038	chloride channel
AQ475_RS08515	COG2855	membrane
AQ475_RS08535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AQ475_RS08545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AQ475_RS08550	COG1609	Transcriptional regulator
AQ475_RS08600	COG0039	L-malate dehydrogenase activity
AQ475_RS08620	COG0598	Magnesium transport protein CorA
AQ475_RS08625	COG2350	Protein conserved in bacteria
AQ475_RS08650	COG3264	Mechanosensitive ion channel
AQ475_RS08650	COG1196	nuclear chromosome segregation
AQ475_RS08680	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AQ475_RS08695	COG4263	nitrous-oxide reductase activity
AQ475_RS08720	COG2376	Dihydroxyacetone kinase
AQ475_RS08735	COG2017	converts alpha-aldose to the beta-anomer
AQ475_RS08740	COG1609	Transcriptional regulator
AQ475_RS08740	COG2207	Transcriptional regulator
AQ475_RS08750	COG4213	ABC transporter substrate-binding protein
AQ475_RS08760	COG4214	carbohydrate transport
AQ475_RS08765	COG1879	ABC-type sugar transport system periplasmic component
AQ475_RS08770	COG1129	ABC transporter
AQ475_RS08775	COG1172	Belongs to the binding-protein-dependent transport system permease family
AQ475_RS08780	COG1172	Belongs to the binding-protein-dependent transport system permease family
AQ475_RS08790	COG2132	Multicopper oxidase
AQ475_RS08805	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AQ475_RS08825	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AQ475_RS08840	COG3040	lipid binding
AQ475_RS08845	COG3002	Belongs to the UPF0753 family
AQ475_RS08850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AQ475_RS08855	COG0583	DNA-binding transcription factor activity
AQ475_RS08880	COG0492	ferredoxin-NADP+ reductase activity
AQ475_RS08895	COG1960	acyl-CoA dehydrogenase activity
AQ475_RS08935	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AQ475_RS08940	COG2207	Transcriptional regulator
AQ475_RS08940	COG1917	Cupin 2, conserved barrel domain protein
AQ475_RS08950	COG0835	chemotaxis
AQ475_RS08970	COG0318	PFAM AMP-dependent synthetase and ligase
AQ475_RS08975	COG2226	methyltransferase
AQ475_RS08980	COG1732	Glycine betaine
AQ475_RS08985	COG1174	glycine betaine transport
AQ475_RS08990	COG1125	glycine betaine transport
AQ475_RS08995	COG1174	glycine betaine transport
AQ475_RS09000	COG1335	isochorismatase
AQ475_RS09005	COG2814	Major facilitator Superfamily
AQ475_RS09025	COG2235	arginine
AQ475_RS09030	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AQ475_RS09050	COG0583	DNA-binding transcription factor activity
AQ475_RS09055	COG0625	glutathione transferase activity
AQ475_RS09060	COG1846	Transcriptional regulator
AQ475_RS09065	COG2807	transmembrane transport
AQ475_RS09070	COG1649	PFAM Uncharacterised BCR, COG1649
AQ475_RS09085	COG2099	Precorrin-6x reductase
AQ475_RS09100	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AQ475_RS09160	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AQ475_RS09185	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AQ475_RS09190	COG4774	siderophore transport
AQ475_RS09195	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AQ475_RS09235	COG1120	ATPase activity
AQ475_RS09260	COG1028	Short-chain dehydrogenase reductase Sdr
AQ475_RS09265	COG1070	Carbohydrate kinase
AQ475_RS09270	COG1063	alcohol dehydrogenase
AQ475_RS09275	COG1172	Belongs to the binding-protein-dependent transport system permease family
AQ475_RS09285	COG1879	ABC-type sugar transport system periplasmic component
AQ475_RS09310	COG1132	(ABC) transporter
AQ475_RS09310	COG2375	cellular response to nickel ion
AQ475_RS09330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AQ475_RS09340	COG1309	transcriptional regulator
AQ475_RS09345	COG0739	heme binding
AQ475_RS09350	COG0765	amino acid transport
AQ475_RS09355	COG4597	amino acid ABC transporter
AQ475_RS09360	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AQ475_RS09405	COG4964	Belongs to the GSP D family
AQ475_RS09430	COG0477	Major facilitator Superfamily
AQ475_RS09435	COG2719	SpoVR family
AQ475_RS09440	COG2718	Belongs to the UPF0229 family
AQ475_RS09445	COG2766	serine protein kinase
AQ475_RS09450	COG0840	transmembrane signaling receptor activity
AQ475_RS09455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AQ475_RS09460	COG1609	Transcriptional regulator
AQ475_RS09465	COG1172	Belongs to the binding-protein-dependent transport system permease family
AQ475_RS09475	COG1879	ABC-type sugar transport system periplasmic component
AQ475_RS09485	COG0583	DNA-binding transcription factor activity
AQ475_RS09490	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AQ475_RS09495	COG4208	sulfate ABC transporter
AQ475_RS09500	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AQ475_RS09505	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AQ475_RS09545	COG0701	Predicted permease
AQ475_RS09550	COG0667	Aldo Keto reductase
AQ475_RS09570	COG1301	dicarboxylic acid transport
AQ475_RS09605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AQ475_RS09670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AQ475_RS09675	COG0765	amino acid transport
AQ475_RS09680	COG0673	inositol 2-dehydrogenase activity
AQ475_RS09685	COG1802	Transcriptional regulator
AQ475_RS09695	COG3023	N-Acetylmuramoyl-L-alanine amidase
AQ475_RS09700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AQ475_RS09705	COG0557	exoribonuclease II activity
AQ475_RS09720	COG0840	transmembrane signaling receptor activity
AQ475_RS09740	COG0519	Catalyzes the synthesis of GMP from XMP
AQ475_RS09745	COG2814	Major facilitator Superfamily
AQ475_RS09755	COG0318	PFAM AMP-dependent synthetase and ligase
AQ475_RS09820	COG4964	Belongs to the GSP D family
AQ475_RS09875	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AQ475_RS09880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AQ475_RS09885	COG0508	dehydrogenase complex catalyzes the overall conversion of
AQ475_RS09890	COG0567	Dehydrogenase, E1 component
AQ475_RS09895	COG1217	gtp-binding protein TYPA
AQ475_RS09900	COG1846	Transcriptional regulator
AQ475_RS09910	COG1566	PFAM secretion protein HlyD family protein
AQ475_RS09915	COG2814	Major facilitator Superfamily
AQ475_RS09920	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AQ475_RS09935	COG2251	uridine kinase activity
AQ475_RS09935	COG0195	Participates in both transcription termination and antitermination
AQ475_RS09945	COG1187	pseudouridine synthase activity
AQ475_RS09950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AQ475_RS09955	COG0583	DNA-binding transcription factor activity
AQ475_RS09995	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AQ475_RS10030	COG0776	regulation of translation
AQ475_RS10055	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AQ475_RS10070	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AQ475_RS10075	COG0251	oxidation-reduction process
AQ475_RS10095	COG0583	DNA-binding transcription factor activity
AQ475_RS10110	COG1028	Short-chain dehydrogenase reductase Sdr
AQ475_RS10140	COG1028	Short-chain dehydrogenase reductase Sdr
AQ475_RS10155	COG0477	Major facilitator Superfamily
AQ475_RS10170	COG1295	ribonuclease BN
AQ475_RS10185	COG0277	FAD linked oxidase domain protein
AQ475_RS10200	COG0583	DNA-binding transcription factor activity
AQ475_RS10225	COG0840	transmembrane signaling receptor activity
AQ475_RS10230	COG2223	nitrite transmembrane transporter activity
AQ475_RS10235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AQ475_RS10240	COG0210	DNA helicase
AQ475_RS10245	COG0525	valine-tRNA ligase activity
AQ475_RS10250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AQ475_RS10260	COG5002	protein histidine kinase activity
AQ475_RS10270	COG0745	RESPONSE REGULATOR receiver
AQ475_RS10280	COG0425	Belongs to the sulfur carrier protein TusA family
AQ475_RS10285	COG0673	inositol 2-dehydrogenase activity
AQ475_RS10290	COG0673	inositol 2-dehydrogenase activity
AQ475_RS10305	COG1172	Belongs to the binding-protein-dependent transport system permease family
AQ475_RS10320	COG3962	Belongs to the TPP enzyme family
AQ475_RS10330	COG3718	enzyme involved in inositol metabolism
AQ475_RS10350	COG0824	Thioesterase
AQ475_RS10365	COG0494	nUDIX hydrolase
AQ475_RS10370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AQ475_RS10380	COG0477	Major facilitator Superfamily
AQ475_RS10395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AQ475_RS10410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AQ475_RS10415	COG1051	belongs to the nudix hydrolase family
AQ475_RS10440	COG3511	phospholipase C
AQ475_RS10460	COG2197	response regulator
AQ475_RS10505	COG0583	DNA-binding transcription factor activity
AQ475_RS10510	COG2814	Major facilitator Superfamily
AQ475_RS10530	COG2963	transposase activity
AQ475_RS10535	COG2801	Transposase and inactivated derivatives
AQ475_RS10665	COG2916	Histone family protein nucleoid-structuring protein H-NS
AQ475_RS10675	COG0583	DNA-binding transcription factor activity
AQ475_RS10750	COG4942	peptidase
AQ475_RS10755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AQ475_RS10770	COG0534	Mate efflux family protein
AQ475_RS10820	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AQ475_RS10825	COG5002	protein histidine kinase activity
AQ475_RS10830	COG0745	RESPONSE REGULATOR receiver
AQ475_RS10845	COG0581	inorganic phosphate transmembrane transporter activity
AQ475_RS10850	COG0573	inorganic phosphate transmembrane transporter activity
AQ475_RS10855	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AQ475_RS10865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AQ475_RS10870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AQ475_RS10880	COG1534	Rna-binding protein
AQ475_RS10890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AQ475_RS10895	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AQ475_RS10905	COG0505	Belongs to the CarA family
AQ475_RS10925	COG0741	lytic transglycosylase activity
AQ475_RS10925	COG1388	LysM domain
AQ475_RS10930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AQ475_RS10935	COG2226	methyltransferase
AQ475_RS10940	COG0328	RNA-DNA hybrid ribonuclease activity
AQ475_RS10945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AQ475_RS10955	COG0477	Major facilitator Superfamily
AQ475_RS10970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AQ475_RS10980	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AQ475_RS11000	COG3052	prosthetic group binding
AQ475_RS11020	COG0583	DNA-binding transcription factor activity
AQ475_RS11025	COG1250	3-hydroxyacyl-CoA dehydrogenase
AQ475_RS11030	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AQ475_RS11045	COG0071	Belongs to the small heat shock protein (HSP20) family
AQ475_RS11065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AQ475_RS11090	COG0583	DNA-binding transcription factor activity
AQ475_RS11120	COG3706	GGDEF domain
AQ475_RS11145	COG1609	Transcriptional regulator
AQ475_RS11150	COG1840	ABC-type Fe3 transport system, periplasmic component
AQ475_RS11155	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AQ475_RS11170	COG1177	transmembrane transport
AQ475_RS11175	COG3842	ATPase activity
AQ475_RS11180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AQ475_RS11185	COG2814	Major facilitator Superfamily
AQ475_RS11190	COG0697	spore germination
AQ475_RS11200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AQ475_RS11205	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AQ475_RS11235	COG0697	spore germination
AQ475_RS11240	COG2200	EAL domain
AQ475_RS11250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AQ475_RS11255	COG1074	ATP-dependent DNA helicase activity
AQ475_RS11260	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AQ475_RS11280	COG1840	ABC-type Fe3 transport system, periplasmic component
AQ475_RS11290	COG3842	ATPase activity
AQ475_RS11295	COG1522	sequence-specific DNA binding
AQ475_RS11310	COG1959	2 iron, 2 sulfur cluster binding
AQ475_RS11335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AQ475_RS11340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AQ475_RS11365	COG2863	cytochrome
AQ475_RS11370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AQ475_RS11385	COG2010	Cytochrome c
AQ475_RS11385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AQ475_RS11390	COG2863	cytochrome
AQ475_RS11420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AQ475_RS11435	COG0006	proline dipeptidase activity
AQ475_RS11440	COG2963	transposase activity
AQ475_RS11445	COG2801	Transposase and inactivated derivatives
AQ475_RS11450	COG2963	transposase activity
AQ475_RS11505	COG2866	Carboxypeptidase
AQ475_RS11520	COG0436	Aminotransferase
AQ475_RS11525	COG0625	glutathione transferase activity
AQ475_RS11530	COG1024	Enoyl-CoA hydratase
AQ475_RS11535	COG0588	phosphoglycerate mutase activity
AQ475_RS11545	COG1960	acyl-CoA dehydrogenase activity
AQ475_RS11560	COG1012	belongs to the aldehyde dehydrogenase family
AQ475_RS11560	COG2030	dehydratase
AQ475_RS11565	COG1960	acyl-CoA dehydrogenase activity
AQ475_RS11570	COG1960	acyl-CoA dehydrogenase activity
AQ475_RS11580	COG0494	nUDIX hydrolase
AQ475_RS11590	COG1007	ATP synthesis coupled electron transport
AQ475_RS11625	COG1034	ATP synthesis coupled electron transport
AQ475_RS11635	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AQ475_RS11670	COG0149	triose-phosphate isomerase activity
AQ475_RS11675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AQ475_RS11675	COG3321	synthase
AQ475_RS11675	COG0604	alcohol dehydrogenase
AQ475_RS11675	COG4221	oxidoreductase activity
AQ475_RS11690	COG0683	leucine binding
AQ475_RS11705	COG0288	reversible hydration of carbon dioxide
AQ475_RS11710	COG0659	secondary active sulfate transmembrane transporter activity
AQ475_RS11720	COG1183	phosphatidylcholine synthase activity
AQ475_RS11740	COG0028	Belongs to the TPP enzyme family
AQ475_RS11770	COG0438	transferase activity, transferring glycosyl groups
AQ475_RS11790	COG1028	Short-chain dehydrogenase reductase Sdr
AQ475_RS11795	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AQ475_RS11805	COG0154	amidase activity
AQ475_RS11815	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AQ475_RS11835	COG2076	Multidrug Resistance protein
AQ475_RS11845	COG0745	RESPONSE REGULATOR receiver
AQ475_RS11850	COG2205	protein histidine kinase activity
AQ475_RS11865	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AQ475_RS11870	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AQ475_RS11890	COG1028	Short-chain dehydrogenase reductase Sdr
AQ475_RS11905	COG0151	Belongs to the GarS family
AQ475_RS11920	COG0799	negative regulation of ribosome biogenesis
AQ475_RS11940	COG2233	PERMEase
AQ475_RS11985	COG1595	DNA-templated transcription, initiation
AQ475_RS11990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AQ475_RS12020	COG0859	PFAM glycosyl transferase family 9
AQ475_RS12060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AQ475_RS12065	COG0513	Belongs to the DEAD box helicase family
AQ475_RS12095	COG1674	ftsk spoiiie
AQ475_RS12100	COG2706	6-phosphogluconolactonase activity
AQ475_RS12105	COG3387	PFAM Glycoside hydrolase 15-related
AQ475_RS12115	COG1309	transcriptional regulator
AQ475_RS12120	COG2878	Part of a membrane complex involved in electron transport
AQ475_RS12125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AQ475_RS12160	COG3135	benzoate transporter
AQ475_RS12175	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AQ475_RS12220	COG0697	spore germination
AQ475_RS12225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AQ475_RS12265	COG0583	DNA-binding transcription factor activity
AQ475_RS12285	COG0488	(ABC) transporter
AQ475_RS12295	COG1773	rubredoxin
AQ475_RS12310	COG2204	response regulator
AQ475_RS12585	COG0582	viral genome integration into host DNA
AQ475_RS12600	COG0582	viral genome integration into host DNA
AQ475_RS12645	COG3436	PFAM IS66 Orf2 family protein
AQ475_RS12650	COG4372	Transposase
AQ475_RS12665	COG3012	SEC-C Motif Domain Protein
AQ475_RS12685	COG1192	Involved in chromosome partitioning
AQ475_RS12710	COG4574	serine-type endopeptidase inhibitor activity
AQ475_RS12730	COG1881	PFAM PEBP family protein
AQ475_RS12735	COG2814	Major facilitator Superfamily
AQ475_RS12755	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AQ475_RS12775	COG1116	anion transmembrane transporter activity
AQ475_RS12780	COG1176	ABC-type spermidine putrescine transport system, permease component I
AQ475_RS12805	COG1741	Belongs to the pirin family
AQ475_RS12815	COG4215	(ABC) transporter
AQ475_RS12845	COG0347	Belongs to the P(II) protein family
AQ475_RS12865	COG2827	Endonuclease containing a URI domain
AQ475_RS12870	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AQ475_RS12885	COG2271	Major facilitator Superfamily
AQ475_RS12910	COG2226	methyltransferase
AQ475_RS12945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AQ475_RS12970	COG0489	protein tyrosine kinase activity
AQ475_RS12975	COG3047	cAMP biosynthetic process
AQ475_RS12975	COG2885	chlorophyll binding
AQ475_RS13000	COG0729	surface antigen
AQ475_RS13010	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AQ475_RS13030	COG0489	protein tyrosine kinase activity
AQ475_RS13035	COG2259	Doxx family
AQ475_RS13040	COG1492	cobalamin metabolic process
AQ475_RS13050	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AQ475_RS13060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AQ475_RS13070	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AQ475_RS13075	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AQ475_RS13080	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AQ475_RS13090	COG4206	TonB-dependent receptor
AQ475_RS13125	COG0583	DNA-binding transcription factor activity
AQ475_RS13155	COG0795	lipopolysaccharide-transporting ATPase activity
AQ475_RS13170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AQ475_RS13170	COG1648	precorrin-2 dehydrogenase activity
AQ475_RS13175	COG2895	sulfate adenylyltransferase (ATP) activity
AQ475_RS13185	COG0175	sulfate reduction
AQ475_RS13200	COG0583	DNA-binding transcription factor activity
AQ475_RS13255	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AQ475_RS13265	COG3586	endonuclease activity
AQ475_RS13280	COG1396	sequence-specific DNA binding
AQ475_RS13285	COG0235	Class ii aldolase
AQ475_RS13290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AQ475_RS13295	COG2258	MOSC domain
AQ475_RS13300	COG2267	carboxylic ester hydrolase activity
AQ475_RS13310	COG0583	DNA-binding transcription factor activity
AQ475_RS13330	COG1187	pseudouridine synthase activity
AQ475_RS13345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AQ475_RS13345	COG0543	2 iron, 2 sulfur cluster binding
AQ475_RS13350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AQ475_RS13355	COG0456	acetyltransferase
AQ475_RS13390	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AQ475_RS13395	COG1047	Peptidyl-prolyl cis-trans
AQ475_RS13415	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AQ475_RS13435	COG3264	Mechanosensitive ion channel
AQ475_RS13435	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AQ475_RS13440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AQ475_RS13440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AQ475_RS13445	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AQ475_RS13450	COG0196	riboflavin kinase activity
AQ475_RS13485	COG1113	amino acid transport
AQ475_RS13490	COG0542	response to heat
AQ475_RS13500	COG1278	Cold shock
AQ475_RS13530	COG0656	L-ascorbic acid biosynthetic process
AQ475_RS13535	COG2188	Transcriptional regulator
AQ475_RS13550	COG2814	Major facilitator Superfamily
AQ475_RS13605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AQ475_RS13610	COG1570	exodeoxyribonuclease VII activity
AQ475_RS13645	COG0728	peptidoglycan biosynthetic process
AQ475_RS13660	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AQ475_RS13680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AQ475_RS13685	COG0318	PFAM AMP-dependent synthetase and ligase
AQ475_RS13690	COG4974	Belongs to the 'phage' integrase family
AQ475_RS13700	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AQ475_RS13705	COG0802	atpase or kinase
AQ475_RS13710	COG0860	N-Acetylmuramoyl-L-alanine amidase
AQ475_RS13720	COG1741	Belongs to the pirin family
AQ475_RS13725	COG3118	belongs to the thioredoxin family
AQ475_RS13730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AQ475_RS13740	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AQ475_RS13750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AQ475_RS13760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AQ475_RS13765	COG1522	sequence-specific DNA binding
AQ475_RS13805	COG1012	belongs to the aldehyde dehydrogenase family
AQ475_RS13815	COG0583	DNA-binding transcription factor activity
AQ475_RS13820	COG0246	Mannitol dehydrogenase
AQ475_RS13825	COG1070	Carbohydrate kinase
AQ475_RS13830	COG2390	Transcriptional regulator
AQ475_RS13855	COG3842	ATPase activity
AQ475_RS13860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AQ475_RS13870	COG1175	transmembrane transport
AQ475_RS13885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AQ475_RS13895	COG0735	belongs to the Fur family
AQ475_RS13905	COG1121	(ABC) transporter
AQ475_RS13910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AQ475_RS13915	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AQ475_RS13930	COG1070	Carbohydrate kinase
AQ475_RS13935	COG2233	PERMEase
AQ475_RS13945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AQ475_RS13950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AQ475_RS13975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AQ475_RS14005	COG0009	L-threonylcarbamoyladenylate synthase
AQ475_RS14010	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AQ475_RS14015	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AQ475_RS14020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AQ475_RS14030	COG0469	pyruvate kinase activity
AQ475_RS14035	COG0126	phosphoglycerate kinase activity
AQ475_RS14060	COG0859	PFAM glycosyl transferase family 9
AQ475_RS14070	COG0429	hydrolase of the alpha beta-hydrolase fold
AQ475_RS14080	COG4783	chaperone-mediated protein folding
AQ475_RS14100	COG3307	-O-antigen
AQ475_RS14105	COG4969	Belongs to the N-Me-Phe pilin family
AQ475_RS14110	COG0861	Integral membrane protein TerC family
AQ475_RS14115	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AQ475_RS14135	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AQ475_RS14180	COG2205	protein histidine kinase activity
AQ475_RS14180	COG0784	Response regulator, receiver
AQ475_RS14185	COG0583	DNA-binding transcription factor activity
AQ475_RS14250	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AQ475_RS14265	COG0840	transmembrane signaling receptor activity
AQ475_RS14295	COG4948	Mandelate Racemase Muconate Lactonizing
AQ475_RS14320	COG0513	Belongs to the DEAD box helicase family
AQ475_RS14365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AQ475_RS14375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AQ475_RS14380	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AQ475_RS14390	COG2814	Major facilitator Superfamily
AQ475_RS14395	COG0583	DNA-binding transcription factor activity
AQ475_RS14405	COG1702	phosphate starvation-inducible protein PhoH
AQ475_RS14415	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AQ475_RS14425	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AQ475_RS14430	COG0752	glycyl-tRNA synthetase alpha subunit
AQ475_RS14435	COG0751	glycine-tRNA ligase activity
AQ475_RS14440	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AQ475_RS14445	COG0204	Acyl-transferase
AQ475_RS14470	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AQ475_RS14490	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AQ475_RS14495	COG5265	(ABC) transporter
AQ475_RS14510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AQ475_RS14515	COG1024	Enoyl-CoA hydratase
AQ475_RS14520	COG0183	Belongs to the thiolase family
AQ475_RS14525	COG1250	3-hydroxyacyl-CoA dehydrogenase
AQ475_RS14525	COG1024	Enoyl-CoA hydratase
AQ475_RS14530	COG1960	acyl-CoA dehydrogenase activity
AQ475_RS14545	COG0494	nUDIX hydrolase
AQ475_RS14605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AQ475_RS14615	COG0251	oxidation-reduction process
AQ475_RS14620	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AQ475_RS14645	COG0477	Major facilitator Superfamily
AQ475_RS14670	COG1596	polysaccharide export
AQ475_RS14675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AQ475_RS14690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AQ475_RS14700	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AQ475_RS14720	COG2204	response regulator
AQ475_RS14755	COG5002	protein histidine kinase activity
AQ475_RS14755	COG5001	Diguanylate cyclase
AQ475_RS14760	COG0235	Class ii aldolase
AQ475_RS14820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AQ475_RS14855	COG0412	Dienelactone hydrolase
AQ475_RS14865	COG3177	Filamentation induced by cAMP protein fic
AQ475_RS14890	COG3012	SEC-C Motif Domain Protein
AQ475_RS14905	COG4372	Transposase
AQ475_RS14910	COG3436	PFAM IS66 Orf2 family protein
AQ475_RS14935	COG0210	DNA helicase
AQ475_RS14975	COG0629	single-stranded DNA binding
AQ475_RS14980	COG2814	Major facilitator Superfamily
AQ475_RS15005	COG1280	lysine exporter protein (LysE YggA)
AQ475_RS15025	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AQ475_RS15040	COG1137	ATPase activity
AQ475_RS15045	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AQ475_RS15050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AQ475_RS15075	COG1194	a g-specific adenine glycosylase
AQ475_RS15105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AQ475_RS15125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AQ475_RS15135	COG0742	ribosomal rna small subunit methyltransferase
AQ475_RS15150	COG0625	glutathione transferase activity
AQ475_RS15155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AQ475_RS15165	COG0243	molybdopterin cofactor binding
AQ475_RS15170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AQ475_RS15185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AQ475_RS15195	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AQ475_RS15200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AQ475_RS15215	COG1294	oxidase, subunit
AQ475_RS15245	COG2190	(PTS) system
AQ475_RS15245	COG1263	PTS System
AQ475_RS15245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AQ475_RS15255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AQ475_RS15260	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AQ475_RS15265	COG2188	Transcriptional regulator
AQ475_RS15270	COG0587	DNA-directed DNA polymerase activity
AQ475_RS15285	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AQ475_RS15305	COG0840	transmembrane signaling receptor activity
AQ475_RS15315	COG1999	signal sequence binding
AQ475_RS15325	COG1612	heme a metabolic process
AQ475_RS15365	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AQ475_RS15380	COG2226	methyltransferase
AQ475_RS15385	COG1040	competence protein
AQ475_RS15395	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AQ475_RS15415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AQ475_RS15425	COG0793	Belongs to the peptidase S41A family
AQ475_RS15430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AQ475_RS15435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AQ475_RS15440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AQ475_RS15450	COG0189	ligase activity
AQ475_RS15460	COG0004	ammonium transporteR
AQ475_RS15470	COG2960	long-chain fatty acid transporting porin activity
AQ475_RS15495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AQ475_RS15500	COG2204	response regulator
AQ475_RS15505	COG4191	Histidine kinase
AQ475_RS15515	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AQ475_RS15525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AQ475_RS15530	COG1960	acyl-CoA dehydrogenase activity
AQ475_RS15535	COG1960	acyl-CoA dehydrogenase activity
AQ475_RS15540	COG1024	Enoyl-CoA hydratase
AQ475_RS15540	COG1250	3-hydroxyacyl-CoA dehydrogenase
AQ475_RS15545	COG0583	DNA-binding transcription factor activity
AQ475_RS15555	COG0405	Gamma-glutamyltransferase
AQ475_RS15585	COG0583	DNA-binding transcription factor activity
AQ475_RS15590	COG2921	Belongs to the UPF0250 family
AQ475_RS15600	COG1686	Belongs to the peptidase S11 family
AQ475_RS15630	COG1127	ABC transporter
AQ475_RS15635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AQ475_RS15640	COG0737	Belongs to the 5'-nucleotidase family
AQ475_RS15665	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AQ475_RS15685	COG1024	Enoyl-CoA hydratase
AQ475_RS15735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AQ475_RS15740	COG0300	oxidoreductase activity
AQ475_RS15745	COG1028	Short-chain dehydrogenase reductase Sdr
AQ475_RS15760	COG0747	negative chemotaxis
AQ475_RS15765	COG0488	(ABC) transporter
AQ475_RS15780	COG0288	reversible hydration of carbon dioxide
AQ475_RS15785	COG0183	Belongs to the thiolase family
AQ475_RS15795	COG3012	SEC-C Motif Domain Protein
AQ475_RS15825	COG3142	Participates in the control of copper homeostasis
AQ475_RS15840	COG1785	Belongs to the alkaline phosphatase family
AQ475_RS15850	COG2200	EAL domain
AQ475_RS15850	COG2199	diguanylate cyclase activity
AQ475_RS15855	COG0025	NhaP-type Na H and K H
AQ475_RS15885	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AQ475_RS15960	COG0582	viral genome integration into host DNA
AQ475_RS15965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AQ475_RS15970	COG0596	Alpha beta hydrolase
AQ475_RS15995	COG3511	phospholipase C
AQ475_RS16010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AQ475_RS16040	COG0596	Alpha beta hydrolase
AQ475_RS16050	COG0583	DNA-binding transcription factor activity
AQ475_RS16055	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AQ475_RS16075	COG0840	transmembrane signaling receptor activity
AQ475_RS16080	COG1609	Transcriptional regulator
AQ475_RS16130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AQ475_RS16145	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AQ475_RS16150	COG1704	LemA family
AQ475_RS16160	COG2217	Heavy metal translocating P-type atpase
AQ475_RS16210	COG0745	RESPONSE REGULATOR receiver
AQ475_RS16230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AQ475_RS16240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AQ475_RS16245	COG0745	RESPONSE REGULATOR receiver
AQ475_RS16250	COG5002	protein histidine kinase activity
AQ475_RS16255	COG0745	RESPONSE REGULATOR receiver
AQ475_RS16320	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AQ475_RS16330	COG2824	Alkylphosphonate utilization operon protein PhnA
AQ475_RS16350	COG0583	DNA-binding transcription factor activity
AQ475_RS16355	COG2233	PERMEase
AQ475_RS16360	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AQ475_RS16370	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AQ475_RS16380	COG1706	bacterial-type flagellum-dependent cell motility
AQ475_RS16385	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AQ475_RS16405	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AQ475_RS16410	COG1558	bacterial-type flagellum-dependent cell motility
AQ475_RS16415	COG1815	bacterial-type flagellum-dependent cell motility
AQ475_RS16425	COG2747	anti-sigma28 factor FlgM
AQ475_RS16450	COG0741	lytic transglycosylase activity
AQ475_RS16455	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AQ475_RS16465	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AQ475_RS16470	COG1984	allophanate hydrolase subunit 2
AQ475_RS16500	COG4608	Belongs to the ABC transporter superfamily
AQ475_RS16505	COG0444	Belongs to the ABC transporter superfamily
AQ475_RS16510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AQ475_RS16515	COG0601	transmembrane transport
AQ475_RS16520	COG0747	negative chemotaxis
AQ475_RS16535	COG0579	oxidoreductase
AQ475_RS16550	COG3568	Endonuclease Exonuclease Phosphatase
AQ475_RS16555	COG1280	lysine exporter protein (LysE YggA)
AQ475_RS16575	COG0531	amino acid
AQ475_RS16590	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AQ475_RS16650	COG1960	acyl-CoA dehydrogenase activity
AQ475_RS16660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AQ475_RS16665	COG2721	sulfolactate sulfo-lyase activity
AQ475_RS16675	COG4948	Mandelate Racemase Muconate Lactonizing
AQ475_RS16680	COG2271	Major facilitator Superfamily
AQ475_RS16690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AQ475_RS16695	COG0583	DNA-binding transcription factor activity
AQ475_RS16710	COG2814	Major facilitator Superfamily
AQ475_RS16730	COG0667	Aldo Keto reductase
AQ475_RS16755	COG1560	Kdo2-lipid A biosynthetic process
AQ475_RS16770	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AQ475_RS16780	COG0523	cobalamin synthesis protein
AQ475_RS16790	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AQ475_RS16800	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AQ475_RS16825	COG1309	transcriptional regulator
AQ475_RS16840	COG2814	Major facilitator Superfamily
AQ475_RS16850	COG2207	Transcriptional regulator
AQ475_RS16855	COG1064	alcohol dehydrogenase
AQ475_RS16860	COG0708	Exodeoxyribonuclease III
AQ475_RS16865	COG2326	polyphosphate kinase activity
AQ475_RS16885	COG1077	Cell shape determining protein MreB Mrl
AQ475_RS16900	COG0768	penicillin binding
AQ475_RS16905	COG0772	Belongs to the SEDS family
AQ475_RS16920	COG0720	synthase
AQ475_RS16925	COG0602	queuosine metabolic process
AQ475_RS16940	COG2204	response regulator
AQ475_RS16945	COG5000	phosphorelay sensor kinase activity
AQ475_RS16955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AQ475_RS16955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AQ475_RS16975	COG0242	peptide deformylase activity
AQ475_RS16980	COG0758	DNA mediated transformation
AQ475_RS16995	COG0583	DNA-binding transcription factor activity
AQ475_RS17000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AQ475_RS17025	COG2963	transposase activity
AQ475_RS17030	COG2801	Transposase and inactivated derivatives
AQ475_RS17045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AQ475_RS17060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AQ475_RS17060	COG2169	Transcriptional regulator
AQ475_RS17080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AQ475_RS17155	COG0582	viral genome integration into host DNA
AQ475_RS17915	COG0210	DNA helicase
AQ475_RS18310	COG2814	Major facilitator Superfamily
AQ475_RS18715	COG0070	glutamate synthase
AQ475_RS18715	COG0067	glutamate synthase
AQ475_RS18715	COG0069	glutamate synthase activity
AQ475_RS18725	COG0070	glutamate synthase
AQ475_RS18725	COG0069	glutamate synthase activity
AQ475_RS18725	COG0067	glutamate synthase
AQ475_RS18730	COG0067	glutamate synthase
AQ475_RS18730	COG0070	glutamate synthase
AQ475_RS18730	COG0069	glutamate synthase activity
AQ475_RS19255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AQ475_RS19400	COG0318	PFAM AMP-dependent synthetase and ligase
AQ475_RS19560	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AQ475_RS19985	COG1301	dicarboxylic acid transport
AQ475_RS20000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AQ475_RS20135	COG0121	glutamine amidotransferase
AQ475_RS20240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AQ475_RS20255	COG0006	proline dipeptidase activity
AQ475_RS20810	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AQ475_RS20905	COG0438	transferase activity, transferring glycosyl groups
AQ475_RS21695	COG2814	Major facilitator Superfamily
AQ475_RS22475	COG1530	ribonuclease E activity
AQ475_RS22700	COG0683	leucine binding
AQ475_RS23230	COG2223	nitrite transmembrane transporter activity
AQ475_RS23275	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AQ475_RS23515	COG0529	Catalyzes the synthesis of activated sulfate
AQ475_RS23635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AQ475_RS23655	COG0024	Methionine aminopeptidase
AQ475_RS24310	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AQ475_RS24480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AQ475_RS24480	COG0047	phosphoribosylformylglycinamidine synthase activity
AQ475_RS24595	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AQ475_RS24705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AQ475_RS24825	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AQ475_RS24995	COG1199	ATP-dependent helicase activity
AQ475_RS25010	COG0564	pseudouridine synthase activity
AQ475_RS25040	COG0183	Belongs to the thiolase family
AQ475_RS25575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AQ475_RS25665	COG2226	methyltransferase
AQ475_RS25665	COG3433	isochorismatase activity
AQ475_RS25665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AQ475_RS25715	COG0300	oxidoreductase activity
AQ475_RS25715	COG3321	synthase
AQ475_RS25715	COG4221	oxidoreductase activity
AQ475_RS25715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AQ475_RS25860	COG1028	Short-chain dehydrogenase reductase Sdr
AQ475_RS25945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AQ475_RS26075	COG2766	serine protein kinase
AQ475_RS26110	COG1129	ABC transporter
AQ475_RS26210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AQ475_RS26835	COG0525	valine-tRNA ligase activity
AQ475_RS26850	COG5002	protein histidine kinase activity
AQ475_RS27310	COG0534	Mate efflux family protein
AQ475_RS27615	COG3842	ATPase activity
AQ475_RS27685	COG2200	EAL domain
AQ475_RS27720	COG1074	ATP-dependent DNA helicase activity
AQ475_RS28570	COG5001	Diguanylate cyclase
AQ475_RS28570	COG3300	MHYT domain
AQ475_RS28845	COG0587	DNA-directed DNA polymerase activity
AQ475_RS28895	COG4372	Transposase
AQ475_RS29045	COG1741	Belongs to the pirin family