locus-tag	class	description
WI24_RS00010	COG0592	DNA-directed DNA polymerase activity
WI24_RS00025	COG0753	catalase activity
WI24_RS00060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WI24_RS00070	COG1024	Enoyl-CoA hydratase
WI24_RS00070	COG1250	3-hydroxyacyl-CoA dehydrogenase
WI24_RS00075	COG0183	Belongs to the thiolase family
WI24_RS00085	COG1960	acyl-CoA dehydrogenase activity
WI24_RS00110	COG1695	Transcriptional regulator
WI24_RS00170	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WI24_RS00185	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WI24_RS00200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WI24_RS00210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WI24_RS00215	COG2226	methyltransferase
WI24_RS00220	COG0789	Transcriptional regulator
WI24_RS00230	COG1987	bacterial-type flagellum assembly
WI24_RS00235	COG1338	Plays a role in the flagellum-specific transport system
WI24_RS00245	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WI24_RS00260	COG1346	cytolysis
WI24_RS00270	COG0583	DNA-binding transcription factor activity
WI24_RS00275	COG2814	Major facilitator Superfamily
WI24_RS00280	COG1846	Transcriptional regulator
WI24_RS00325	COG2165	general secretion pathway protein
WI24_RS00360	COG0523	cobalamin synthesis protein
WI24_RS00390	COG0519	Catalyzes the synthesis of GMP from XMP
WI24_RS00390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WI24_RS00395	COG1902	pentaerythritol trinitrate reductase activity
WI24_RS00410	COG0642	Histidine kinase
WI24_RS00430	COG3186	Phenylalanine-4-hydroxylase
WI24_RS00435	COG1522	sequence-specific DNA binding
WI24_RS00445	COG0583	DNA-binding transcription factor activity
WI24_RS00455	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
WI24_RS00520	COG1192	Involved in chromosome partitioning
WI24_RS00530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WI24_RS00540	COG0356	it plays a direct role in the translocation of protons across the membrane
WI24_RS00580	COG0318	PFAM AMP-dependent synthetase and ligase
WI24_RS00595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WI24_RS00605	COG0506	proline dehydrogenase activity
WI24_RS00605	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WI24_RS00605	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WI24_RS00610	COG0683	leucine binding
WI24_RS00620	COG1960	acyl-CoA dehydrogenase activity
WI24_RS00630	COG0436	Aminotransferase
WI24_RS00650	COG0789	Transcriptional regulator
WI24_RS00670	COG0668	transmembrane transport
WI24_RS00680	COG0531	amino acid
WI24_RS00685	COG4303	Ethanolamine ammonia lyase large subunit
WI24_RS00690	COG4302	ethanolamine ammonia-lyase activity
WI24_RS00695	COG0583	DNA-binding transcription factor activity
WI24_RS00705	COG1012	belongs to the aldehyde dehydrogenase family
WI24_RS00710	COG2207	Transcriptional regulator
WI24_RS00725	COG1760	l-serine dehydratase
WI24_RS00745	COG0509	glycine decarboxylation via glycine cleavage system
WI24_RS00760	COG0673	inositol 2-dehydrogenase activity
WI24_RS00775	COG0210	DNA helicase
WI24_RS00820	COG3397	chitin binding
WI24_RS00880	COG0596	Alpha beta hydrolase
WI24_RS00950	COG2818	Glycosylase
WI24_RS00965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WI24_RS00970	COG2916	Histone family protein nucleoid-structuring protein H-NS
WI24_RS00975	COG0438	transferase activity, transferring glycosyl groups
WI24_RS01015	COG0835	chemotaxis
WI24_RS01025	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WI24_RS01040	COG0745	RESPONSE REGULATOR receiver
WI24_RS01045	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WI24_RS01065	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
WI24_RS01070	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WI24_RS01075	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WI24_RS01085	COG2894	cell division
WI24_RS01100	COG1950	PFAM Membrane protein of
WI24_RS01105	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
WI24_RS01120	COG2070	2-Nitropropane dioxygenase
WI24_RS01145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WI24_RS01150	COG1522	sequence-specific DNA binding
WI24_RS01160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WI24_RS01180	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WI24_RS01185	COG2823	Periplasmic or secreted lipoprotein
WI24_RS01190	COG4654	Cytochrome c, class I
WI24_RS01200	COG1113	amino acid transport
WI24_RS01230	COG2084	Dehydrogenase
WI24_RS01235	COG1280	lysine exporter protein (LysE YggA)
WI24_RS01240	COG2814	Major facilitator Superfamily
WI24_RS01245	COG0583	DNA-binding transcription factor activity
WI24_RS01265	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WI24_RS01275	COG1881	PFAM PEBP family protein
WI24_RS01280	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WI24_RS01285	COG0280	phosphate acetyltransferase
WI24_RS01285	COG0281	malic enzyme
WI24_RS01305	COG1522	sequence-specific DNA binding
WI24_RS01325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WI24_RS01330	COG2151	metal-sulfur cluster biosynthetic enzyme
WI24_RS01335	COG3396	Phenylacetate-CoA oxygenase
WI24_RS01340	COG3460	Phenylacetate-CoA oxygenase
WI24_RS01345	COG3396	Phenylacetate-CoA oxygenase
WI24_RS01380	COG3012	SEC-C Motif Domain Protein
WI24_RS01415	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WI24_RS01455	COG0514	ATP-dependent DNA helicase (RecQ)
WI24_RS01585	COG0201	protein transport
WI24_RS01630	COG4232	protein-disulfide reductase activity
WI24_RS01650	COG1333	cytochrome c biogenesis protein
WI24_RS01655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WI24_RS01660	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WI24_RS01665	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
WI24_RS01720	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WI24_RS01735	COG0395	ABC-type sugar transport system, permease component
WI24_RS01745	COG0584	glycerophosphoryl diester phosphodiesterase
WI24_RS01760	COG0069	glutamate synthase activity
WI24_RS01760	COG0067	glutamate synthase
WI24_RS01760	COG0070	glutamate synthase
WI24_RS01770	COG1115	amino acid carrier protein
WI24_RS01785	COG4178	(ABC) transporter
WI24_RS01810	COG1127	ABC transporter
WI24_RS01815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WI24_RS01820	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WI24_RS01840	COG1131	(ABC) transporter
WI24_RS01845	COG0842	Transport permease protein
WI24_RS01870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WI24_RS01880	COG2095	MarC family integral membrane protein
WI24_RS01930	COG0805	protein transport
WI24_RS01935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WI24_RS01940	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WI24_RS01945	COG0723	plastoquinol--plastocyanin reductase activity
WI24_RS01950	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WI24_RS01955	COG2857	Cytochrome c1
WI24_RS01960	COG0625	glutathione transferase activity
WI24_RS01965	COG2969	positive regulation of protein catabolic process
WI24_RS02060	COG5377	YqaJ viral recombinase family
WI24_RS02085	COG1205	dead DEAH box helicase
WI24_RS02085	COG1111	helicase
WI24_RS02135	COG0582	viral genome integration into host DNA
WI24_RS02250	COG0308	aminopeptidase N
WI24_RS02295	COG0443	Heat shock 70 kDa protein
WI24_RS02300	COG1278	Cold shock
WI24_RS02305	COG0531	amino acid
WI24_RS02310	COG3384	dioxygenase
WI24_RS02320	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WI24_RS02325	COG2890	protein-(glutamine-N5) methyltransferase activity
WI24_RS02345	COG0006	proline dipeptidase activity
WI24_RS02350	COG1335	isochorismatase
WI24_RS02360	COG0488	(ABC) transporter
WI24_RS02390	COG0012	GTP binding
WI24_RS02405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WI24_RS02410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WI24_RS02425	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WI24_RS02445	COG0512	Glutamine amidotransferase of anthranilate synthase
WI24_RS02455	COG0546	phosphoglycolate phosphatase activity
WI24_RS02460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WI24_RS02465	COG2967	ApaG domain
WI24_RS02470	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WI24_RS02480	COG2050	protein possibly involved in aromatic compounds catabolism
WI24_RS02485	COG1024	Enoyl-CoA hydratase
WI24_RS02490	COG0183	Belongs to the thiolase family
WI24_RS02500	COG1024	Enoyl-CoA hydratase
WI24_RS02530	COG0243	molybdopterin cofactor binding
WI24_RS02535	COG0318	PFAM AMP-dependent synthetase and ligase
WI24_RS02540	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WI24_RS02560	COG3116	cell division
WI24_RS02570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WI24_RS02575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WI24_RS02610	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WI24_RS02625	COG0678	peroxiredoxin activity
WI24_RS02665	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
WI24_RS02680	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WI24_RS02690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WI24_RS02695	COG4536	flavin adenine dinucleotide binding
WI24_RS02705	COG0142	geranyltranstransferase activity
WI24_RS02750	COG2095	MarC family integral membrane protein
WI24_RS02755	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
WI24_RS02760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WI24_RS02780	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WI24_RS02780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WI24_RS02800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WI24_RS02805	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
WI24_RS02820	COG0439	Biotin carboxylase
WI24_RS02825	COG0511	ligase activity, forming carbon-carbon bonds
WI24_RS02830	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WI24_RS02835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WI24_RS02845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WI24_RS02850	COG3150	esterase
WI24_RS02855	COG0557	exoribonuclease II activity
WI24_RS02860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WI24_RS02880	COG1414	Transcriptional regulator
WI24_RS02885	COG3734	2-keto-3-deoxy-galactonokinase
WI24_RS02890	COG0800	Aldolase
WI24_RS02895	COG1028	Short-chain dehydrogenase reductase Sdr
WI24_RS02910	COG1172	Belongs to the binding-protein-dependent transport system permease family
WI24_RS02915	COG1028	Short-chain dehydrogenase reductase Sdr
WI24_RS02925	COG0284	orotidine-5'-phosphate decarboxylase activity
WI24_RS02930	COG1546	Belongs to the CinA family
WI24_RS02935	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WI24_RS02950	COG2801	Transposase and inactivated derivatives
WI24_RS02955	COG2963	transposase activity
WI24_RS02975	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WI24_RS02985	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WI24_RS02990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WI24_RS02995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WI24_RS03000	COG2814	Major facilitator Superfamily
WI24_RS03015	COG0583	DNA-binding transcription factor activity
WI24_RS03025	COG1301	dicarboxylic acid transport
WI24_RS03030	COG4266	Belongs to the allantoicase family
WI24_RS03035	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
WI24_RS03040	COG0735	belongs to the Fur family
WI24_RS03045	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WI24_RS03070	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
WI24_RS03075	COG1466	dna polymerase III delta subunit
WI24_RS03085	COG1981	membrane
WI24_RS03090	COG1737	Transcriptional regulator
WI24_RS03090	COG0837	glucose binding
WI24_RS03100	COG0800	Aldolase
WI24_RS03120	COG2223	nitrite transmembrane transporter activity
WI24_RS03125	COG0583	DNA-binding transcription factor activity
WI24_RS03130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WI24_RS03135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WI24_RS03140	COG0765	amino acid transport
WI24_RS03145	COG0765	amino acid transport
WI24_RS03150	COG1126	abc transporter atp-binding protein
WI24_RS03155	COG0121	glutamine amidotransferase
WI24_RS03160	COG0418	dihydroorotase activity
WI24_RS03195	COG1917	Cupin 2, conserved barrel domain protein
WI24_RS03195	COG4977	sequence-specific DNA binding
WI24_RS03200	COG0625	glutathione transferase activity
WI24_RS03205	COG0625	glutathione transferase activity
WI24_RS03225	COG0588	phosphoglycerate mutase activity
WI24_RS03265	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
WI24_RS03270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WI24_RS03275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WI24_RS03280	COG0006	proline dipeptidase activity
WI24_RS03285	COG0625	glutathione transferase activity
WI24_RS03295	COG0069	glutamate synthase activity
WI24_RS03355	COG3008	intermembrane lipid transfer
WI24_RS03355	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WI24_RS03360	COG2995	paraquat-inducible protein a
WI24_RS03375	COG3038	cytochrome b561
WI24_RS03380	COG2353	YceI-like domain
WI24_RS03385	COG2353	YceI-like domain
WI24_RS03395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WI24_RS03400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WI24_RS03405	COG1862	Preprotein translocase
WI24_RS03410	COG0343	queuine tRNA-ribosyltransferase activity
WI24_RS03420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WI24_RS03440	COG0783	Belongs to the Dps family
WI24_RS03470	COG0247	lactate metabolic process
WI24_RS03475	COG0277	FAD linked oxidase domain protein
WI24_RS03480	COG0277	FAD linked oxidase domain protein
WI24_RS03485	COG0277	FAD linked oxidase domain protein
WI24_RS03490	COG2096	Adenosyltransferase
WI24_RS03495	COG1017	nitric oxide dioxygenase activity
WI24_RS03495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WI24_RS03500	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WI24_RS03505	COG0312	modulator of DNA gyrase
WI24_RS03510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WI24_RS03515	COG3164	Protein of unknown function
WI24_RS03520	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WI24_RS03525	COG0497	DNA recombination
WI24_RS03570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WI24_RS03585	COG1428	Deoxynucleoside kinase
WI24_RS03590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WI24_RS03595	COG0617	tRNA 3'-terminal CCA addition
WI24_RS03605	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WI24_RS03630	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WI24_RS03635	COG0586	Pfam SNARE associated Golgi protein
WI24_RS03735	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WI24_RS03750	COG1368	sulfuric ester hydrolase activity
WI24_RS03755	COG1028	Short-chain dehydrogenase reductase Sdr
WI24_RS03755	COG0604	alcohol dehydrogenase
WI24_RS03755	COG3321	synthase
WI24_RS03760	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WI24_RS03765	COG0156	8-amino-7-oxononanoate synthase activity
WI24_RS03775	COG2963	transposase activity
WI24_RS03780	COG2801	Transposase and inactivated derivatives
WI24_RS03815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WI24_RS03820	COG0489	protein tyrosine kinase activity
WI24_RS03820	COG3206	protein involved in exopolysaccharide biosynthesis
WI24_RS03830	COG3562	capsule polysaccharide
WI24_RS03835	COG1045	serine acetyltransferase
WI24_RS03850	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WI24_RS03855	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WI24_RS03860	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
WI24_RS03860	COG0517	IMP dehydrogenase activity
WI24_RS03890	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WI24_RS03935	COG0824	Thioesterase
WI24_RS03940	COG4221	oxidoreductase activity
WI24_RS03995	COG0450	alkyl hydroperoxide reductase
WI24_RS04000	COG1960	acyl-CoA dehydrogenase activity
WI24_RS04035	COG2814	Major facilitator Superfamily
WI24_RS04055	COG2814	Major facilitator Superfamily
WI24_RS04060	COG0778	Nitroreductase
WI24_RS04065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WI24_RS04070	COG0583	DNA-binding transcription factor activity
WI24_RS04075	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WI24_RS04100	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WI24_RS04115	COG4774	siderophore transport
WI24_RS04120	COG1120	ATPase activity
WI24_RS04130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WI24_RS04170	COG0730	response to heat
WI24_RS04185	COG1280	lysine exporter protein (LysE YggA)
WI24_RS04235	COG0604	alcohol dehydrogenase
WI24_RS04240	COG1733	regulation of RNA biosynthetic process
WI24_RS04250	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WI24_RS04265	COG1773	rubredoxin
WI24_RS04285	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
WI24_RS04360	COG1215	transferase activity, transferring glycosyl groups
WI24_RS04375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WI24_RS04390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WI24_RS04415	COG0859	PFAM glycosyl transferase family 9
WI24_RS04470	COG1129	ABC transporter
WI24_RS04495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WI24_RS04505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WI24_RS04515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WI24_RS04585	COG2963	transposase activity
WI24_RS04590	COG2801	Transposase and inactivated derivatives
WI24_RS04600	COG4372	Transposase
WI24_RS04605	COG3436	PFAM IS66 Orf2 family protein
WI24_RS04645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
WI24_RS04665	COG0762	integral membrane protein
WI24_RS04705	COG0436	Aminotransferase
WI24_RS04730	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WI24_RS04730	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WI24_RS04750	COG2814	Major facilitator Superfamily
WI24_RS04755	COG1126	abc transporter atp-binding protein
WI24_RS04760	COG0765	amino acid transport
WI24_RS04765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WI24_RS04780	COG0363	glucosamine-6-phosphate deaminase activity
WI24_RS04785	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WI24_RS04795	COG1175	transmembrane transport
WI24_RS04800	COG0395	ABC-type sugar transport system, permease component
WI24_RS04805	COG3842	ATPase activity
WI24_RS04810	COG2860	membrane
WI24_RS04815	COG1193	negative regulation of DNA recombination
WI24_RS04820	COG0492	ferredoxin-NADP+ reductase activity
WI24_RS04825	COG1674	ftsk spoiiie
WI24_RS04830	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WI24_RS04835	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WI24_RS04870	COG2894	cell division
WI24_RS04890	COG0859	PFAM glycosyl transferase family 9
WI24_RS04900	COG0477	Major facilitator Superfamily
WI24_RS04925	COG3328	transposase activity
WI24_RS05010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WI24_RS05015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WI24_RS05025	COG1561	YicC-like family, N-terminal region
WI24_RS05040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WI24_RS05060	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WI24_RS05070	COG1278	Cold shock
WI24_RS05075	COG2176	DNA-directed DNA polymerase activity
WI24_RS05090	COG4772	TonB-dependent receptor
WI24_RS05125	COG0583	DNA-binding transcription factor activity
WI24_RS05140	COG0308	aminopeptidase N
WI24_RS05150	COG2119	membrane
WI24_RS05155	COG0402	S-adenosylhomocysteine deaminase activity
WI24_RS05160	COG2252	PERMEase
WI24_RS05165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WI24_RS05190	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WI24_RS05215	COG3383	formate dehydrogenase (NAD+) activity
WI24_RS05230	COG1910	domain protein
WI24_RS05240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WI24_RS05250	COG0546	phosphoglycolate phosphatase activity
WI24_RS05275	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WI24_RS05280	COG1605	Chorismate mutase
WI24_RS05280	COG0077	Prephenate dehydratase
WI24_RS05285	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WI24_RS05310	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WI24_RS05320	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WI24_RS05345	COG2951	lytic endotransglycosylase activity
WI24_RS05350	COG0123	including yeast histone deacetylase and acetoin utilization protein
WI24_RS05355	COG2267	carboxylic ester hydrolase activity
WI24_RS05365	COG2011	ABC-type metal ion transport system permease component
WI24_RS05370	COG1464	Belongs to the NlpA lipoprotein family
WI24_RS05385	COG1960	acyl-CoA dehydrogenase activity
WI24_RS05460	COG0501	Belongs to the peptidase M48B family
WI24_RS05470	COG0521	Mo-molybdopterin cofactor biosynthetic process
WI24_RS05475	COG3028	Belongs to the UPF0307 family
WI24_RS05480	COG0312	modulator of DNA gyrase
WI24_RS05485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
WI24_RS05515	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WI24_RS05525	COG0640	Transcriptional regulator
WI24_RS05545	COG0114	fumarate hydratase activity
WI24_RS05550	COG0534	Mate efflux family protein
WI24_RS05555	COG2501	S4 domain
WI24_RS05575	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
WI24_RS05585	COG3045	CreA protein
WI24_RS05600	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WI24_RS05605	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WI24_RS05650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WI24_RS05655	COG1530	ribonuclease E activity
WI24_RS05665	COG0546	phosphoglycolate phosphatase activity
WI24_RS05690	COG1399	metal-binding, possibly nucleic acid-binding protein
WI24_RS05725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WI24_RS05745	COG3026	antisigma factor binding
WI24_RS05750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WI24_RS05765	COG0681	Belongs to the peptidase S26 family
WI24_RS05770	COG0571	ribonuclease III activity
WI24_RS05775	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WI24_RS05785	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WI24_RS05800	COG2204	response regulator
WI24_RS05820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WI24_RS05845	COG1956	GAF domain-containing protein
WI24_RS05850	COG0583	DNA-binding transcription factor activity
WI24_RS05860	COG2153	protein acetylation
WI24_RS05885	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
WI24_RS05890	COG1132	(ABC) transporter
WI24_RS05895	COG0438	transferase activity, transferring glycosyl groups
WI24_RS05910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WI24_RS05915	COG0683	leucine binding
WI24_RS05920	COG3511	phospholipase C
WI24_RS05930	COG0596	Alpha beta hydrolase
WI24_RS05935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WI24_RS05950	COG3394	polysaccharide catabolic process
WI24_RS05985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WI24_RS06015	COG0625	glutathione transferase activity
WI24_RS06025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WI24_RS06035	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WI24_RS06060	COG1959	2 iron, 2 sulfur cluster binding
WI24_RS06070	COG2151	metal-sulfur cluster biosynthetic enzyme
WI24_RS06075	COG0822	iron-sulfur transferase activity
WI24_RS06080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WI24_RS06090	COG0396	ATPase activity
WI24_RS06095	COG0719	Fe-S assembly protein
WI24_RS06105	COG0840	transmembrane signaling receptor activity
WI24_RS06110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WI24_RS06115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WI24_RS06130	COG0826	peptidase U32
WI24_RS06135	COG0826	peptidase U32
WI24_RS06140	COG3154	lipid carrier protein
WI24_RS06175	COG2151	metal-sulfur cluster biosynthetic enzyme
WI24_RS06190	COG0415	Belongs to the DNA photolyase family
WI24_RS06195	COG0529	Catalyzes the synthesis of activated sulfate
WI24_RS06235	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
WI24_RS06250	COG0402	S-adenosylhomocysteine deaminase activity
WI24_RS06265	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WI24_RS06270	COG0174	glutamine synthetase
WI24_RS06345	COG0582	viral genome integration into host DNA
WI24_RS06355	COG3668	Plasmid stabilization system
WI24_RS06370	COG0583	DNA-binding transcription factor activity
WI24_RS06375	COG1960	acyl-CoA dehydrogenase activity
WI24_RS06385	COG0477	Major facilitator Superfamily
WI24_RS06395	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WI24_RS06395	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WI24_RS06400	COG1643	Atp-dependent helicase
WI24_RS06420	COG1546	Belongs to the CinA family
WI24_RS06420	COG1058	Belongs to the CinA family
WI24_RS06430	COG0174	glutamine synthetase
WI24_RS06465	COG2197	response regulator
WI24_RS06470	COG4585	Histidine kinase
WI24_RS06475	COG2181	nitrate reductase activity
WI24_RS06480	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
WI24_RS06485	COG1140	nitrate reductase beta subunit
WI24_RS06490	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
WI24_RS06495	COG2223	nitrite transmembrane transporter activity
WI24_RS06510	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WI24_RS06515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WI24_RS06520	COG0339	signal peptide processing
WI24_RS06530	COG4566	intracellular signal transduction
WI24_RS06540	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WI24_RS06545	COG0508	dehydrogenase complex catalyzes the overall conversion of
WI24_RS06550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WI24_RS06565	COG1414	Transcriptional regulator
WI24_RS06570	COG0247	lactate metabolic process
WI24_RS06585	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WI24_RS06595	COG1104	cysteine desulfurase activity
WI24_RS06600	COG0822	iron-sulfur transferase activity
WI24_RS06605	COG0316	Belongs to the HesB IscA family
WI24_RS06625	COG2975	iron-sulfur cluster assembly
WI24_RS06655	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WI24_RS06675	COG0084	hydrolase, TatD family'
WI24_RS06680	COG0658	competence protein
WI24_RS06680	COG2333	competence protein COMEC
WI24_RS06685	COG2267	carboxylic ester hydrolase activity
WI24_RS06710	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WI24_RS06720	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WI24_RS06730	COG2833	Protein of unknown function (DUF455)
WI24_RS06735	COG0596	Alpha beta hydrolase
WI24_RS06740	COG0613	PHP domain protein
WI24_RS06745	COG0009	L-threonylcarbamoyladenylate synthase
WI24_RS06750	COG1994	Peptidase M50
WI24_RS06755	COG0180	Tryptophanyl-tRNA synthetase
WI24_RS06765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WI24_RS06770	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WI24_RS06775	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
WI24_RS06780	COG2850	peptidyl-arginine hydroxylation
WI24_RS06805	COG0483	inositol monophosphate 1-phosphatase activity
WI24_RS06815	COG1045	serine acetyltransferase
WI24_RS06825	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WI24_RS06835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WI24_RS06860	COG0037	tRNA processing
WI24_RS06865	COG0527	aspartate kinase activity
WI24_RS06890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WI24_RS06895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WI24_RS06900	COG0529	Catalyzes the synthesis of activated sulfate
WI24_RS06900	COG2895	sulfate adenylyltransferase (ATP) activity
WI24_RS06930	COG2175	clavaminate synthase activity
WI24_RS06950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WI24_RS06955	COG3958	Transketolase
WI24_RS06970	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WI24_RS06985	COG2895	sulfate adenylyltransferase (ATP) activity
WI24_RS06990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WI24_RS07005	COG0024	Methionine aminopeptidase
WI24_RS07015	COG0243	molybdopterin cofactor binding
WI24_RS07030	COG4166	transmembrane transport
WI24_RS07035	COG4174	ABC transporter (Permease)
WI24_RS07040	COG4239	(ABC) transporter, permease
WI24_RS07045	COG4172	Belongs to the ABC transporter superfamily
WI24_RS07050	COG0791	NLP P60 protein
WI24_RS07055	COG1752	Esterase of the alpha-beta hydrolase superfamily
WI24_RS07110	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WI24_RS07120	COG0583	DNA-binding transcription factor activity
WI24_RS07130	COG2224	Isocitrate lyase
WI24_RS07135	COG0513	Belongs to the DEAD box helicase family
WI24_RS07145	COG1214	PFAM Peptidase M22, glycoprotease
WI24_RS07155	COG1573	uracil-dna glycosylase
WI24_RS07165	COG0351	phosphomethylpyrimidine kinase
WI24_RS07170	COG0477	Major facilitator Superfamily
WI24_RS07190	COG0488	(ABC) transporter
WI24_RS07195	COG0386	Belongs to the glutathione peroxidase family
WI24_RS07205	COG2890	protein-(glutamine-N5) methyltransferase activity
WI24_RS07215	COG1393	Belongs to the ArsC family
WI24_RS07255	COG0242	peptide deformylase activity
WI24_RS07260	COG1187	pseudouridine synthase activity
WI24_RS07270	COG0024	Methionine aminopeptidase
WI24_RS07295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WI24_RS07310	COG0750	zinc metalloprotease
WI24_RS07350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WI24_RS07380	COG0330	HflC and HflK could
WI24_RS07400	COG0697	spore germination
WI24_RS07455	COG1619	proteins homologs of microcin C7 resistance protein MccF
WI24_RS07465	COG1953	Uracil, thiamine, allantoin
WI24_RS07480	COG3195	allantoin biosynthetic process
WI24_RS07480	COG3648	Uricase
WI24_RS07485	COG4266	Belongs to the allantoicase family
WI24_RS07520	COG3360	Dodecin
WI24_RS07570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WI24_RS07585	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WI24_RS07600	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WI24_RS07705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WI24_RS07715	COG1846	Transcriptional regulator
WI24_RS07720	COG1929	Belongs to the glycerate kinase type-1 family
WI24_RS07740	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WI24_RS07775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WI24_RS07785	COG4181	ATPase activity
WI24_RS07800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WI24_RS07810	COG0047	phosphoribosylformylglycinamidine synthase activity
WI24_RS07810	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WI24_RS07815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WI24_RS07840	COG0318	PFAM AMP-dependent synthetase and ligase
WI24_RS07845	COG1024	Enoyl-CoA hydratase
WI24_RS07845	COG1250	3-hydroxyacyl-CoA dehydrogenase
WI24_RS07850	COG1335	isochorismatase
WI24_RS07855	COG0183	Belongs to the thiolase family
WI24_RS07880	COG2130	NADP-dependent
WI24_RS07885	COG0657	acetylesterase activity
WI24_RS07890	COG2153	protein acetylation
WI24_RS07900	COG0354	folic acid binding
WI24_RS07905	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WI24_RS07920	COG1247	-acetyltransferase
WI24_RS07925	COG0084	hydrolase, TatD family'
WI24_RS07950	COG0438	transferase activity, transferring glycosyl groups
WI24_RS07970	COG0252	asparaginase activity
WI24_RS07975	COG1652	LysM domain
WI24_RS07985	COG2084	Dehydrogenase
WI24_RS07990	COG3622	Belongs to the hyi family
WI24_RS07995	COG3960	tartronate-semialdehyde synthase activity
WI24_RS08000	COG0583	DNA-binding transcription factor activity
WI24_RS08055	COG0306	phosphate transporter
WI24_RS08060	COG0791	NLP P60 protein
WI24_RS08065	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WI24_RS08070	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WI24_RS08075	COG0726	polysaccharide deacetylase
WI24_RS08080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WI24_RS08080	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WI24_RS08090	COG0463	Glycosyl transferase, family 2
WI24_RS08095	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WI24_RS08100	COG2076	Multidrug Resistance protein
WI24_RS08105	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WI24_RS08115	COG0436	Aminotransferase
WI24_RS08135	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WI24_RS08140	COG0314	molybdopterin synthase activity
WI24_RS08145	COG2346	COG2346, Truncated hemoglobins
WI24_RS08150	COG1959	2 iron, 2 sulfur cluster binding
WI24_RS08155	COG0542	response to heat
WI24_RS08185	COG0534	Mate efflux family protein
WI24_RS08200	COG3228	Belongs to the MtfA family
WI24_RS08210	COG0789	Transcriptional regulator
WI24_RS08220	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WI24_RS08240	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WI24_RS08255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WI24_RS08295	COG0670	Belongs to the BI1 family
WI24_RS08330	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WI24_RS08345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WI24_RS08350	COG0330	HflC and HflK could
WI24_RS08355	COG0330	HflC and HflK could
WI24_RS08360	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
WI24_RS08375	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
WI24_RS08385	COG2183	response to ionizing radiation
WI24_RS08400	COG1199	ATP-dependent helicase activity
WI24_RS08410	COG0564	pseudouridine synthase activity
WI24_RS08415	COG1496	oxidoreductase activity
WI24_RS08420	COG3243	poly(R)-hydroxyalkanoic acid synthase
WI24_RS08425	COG0183	Belongs to the thiolase family
WI24_RS08430	COG1028	Short-chain dehydrogenase reductase Sdr
WI24_RS08450	COG0183	Belongs to the thiolase family
WI24_RS08460	COG0626	cystathionine gamma-synthase activity
WI24_RS08465	COG0560	Phosphoserine phosphatase
WI24_RS08480	COG0390	transport system, permease component
WI24_RS08485	COG1122	ATPase activity
WI24_RS08490	COG2982	Protein involved in outer membrane biogenesis
WI24_RS08495	COG0488	(ABC) transporter
WI24_RS08510	COG2070	2-Nitropropane dioxygenase
WI24_RS08515	COG3047	cAMP biosynthetic process
WI24_RS08525	COG1914	H( )-stimulated, divalent metal cation uptake system
WI24_RS08530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WI24_RS08535	COG3842	ATPase activity
WI24_RS08540	COG1176	ABC-type spermidine putrescine transport system, permease component I
WI24_RS08545	COG1177	transmembrane transport
WI24_RS08575	COG3655	Transcriptional regulator
WI24_RS08585	COG1538	Outer membrane efflux protein
WI24_RS08590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WI24_RS08600	COG1309	transcriptional regulator
WI24_RS08605	COG0038	chloride channel
WI24_RS08610	COG2855	membrane
WI24_RS08630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WI24_RS08640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WI24_RS08645	COG1609	Transcriptional regulator
WI24_RS08695	COG0039	L-malate dehydrogenase activity
WI24_RS08715	COG0598	Magnesium transport protein CorA
WI24_RS08720	COG2350	Protein conserved in bacteria
WI24_RS08745	COG1196	nuclear chromosome segregation
WI24_RS08745	COG3264	Mechanosensitive ion channel
WI24_RS08775	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
WI24_RS08790	COG4263	nitrous-oxide reductase activity
WI24_RS08815	COG2376	Dihydroxyacetone kinase
WI24_RS08830	COG2017	converts alpha-aldose to the beta-anomer
WI24_RS08835	COG1609	Transcriptional regulator
WI24_RS08835	COG2207	Transcriptional regulator
WI24_RS08845	COG4213	ABC transporter substrate-binding protein
WI24_RS08855	COG4214	carbohydrate transport
WI24_RS08860	COG1879	ABC-type sugar transport system periplasmic component
WI24_RS08865	COG1129	ABC transporter
WI24_RS08870	COG1172	Belongs to the binding-protein-dependent transport system permease family
WI24_RS08875	COG1172	Belongs to the binding-protein-dependent transport system permease family
WI24_RS08885	COG2132	Multicopper oxidase
WI24_RS08900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WI24_RS08920	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WI24_RS08935	COG3040	lipid binding
WI24_RS08940	COG3002	Belongs to the UPF0753 family
WI24_RS08945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WI24_RS08950	COG0583	DNA-binding transcription factor activity
WI24_RS09020	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WI24_RS09025	COG2207	Transcriptional regulator
WI24_RS09025	COG1917	Cupin 2, conserved barrel domain protein
WI24_RS09035	COG0835	chemotaxis
WI24_RS09055	COG0318	PFAM AMP-dependent synthetase and ligase
WI24_RS09060	COG2226	methyltransferase
WI24_RS09065	COG1732	Glycine betaine
WI24_RS09070	COG1174	glycine betaine transport
WI24_RS09075	COG1125	glycine betaine transport
WI24_RS09080	COG1174	glycine betaine transport
WI24_RS09085	COG1335	isochorismatase
WI24_RS09090	COG2814	Major facilitator Superfamily
WI24_RS09110	COG2235	arginine
WI24_RS09115	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WI24_RS09135	COG0583	DNA-binding transcription factor activity
WI24_RS09140	COG0625	glutathione transferase activity
WI24_RS09145	COG1846	Transcriptional regulator
WI24_RS09150	COG2807	transmembrane transport
WI24_RS09155	COG1649	PFAM Uncharacterised BCR, COG1649
WI24_RS09170	COG2099	Precorrin-6x reductase
WI24_RS09185	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WI24_RS09215	COG0400	carboxylic ester hydrolase activity
WI24_RS09245	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
WI24_RS09270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WI24_RS09275	COG4774	siderophore transport
WI24_RS09280	COG3486	L-lysine 6-monooxygenase (NADPH) activity
WI24_RS09320	COG1120	ATPase activity
WI24_RS09345	COG1028	Short-chain dehydrogenase reductase Sdr
WI24_RS09350	COG1070	Carbohydrate kinase
WI24_RS09355	COG1063	alcohol dehydrogenase
WI24_RS09360	COG1172	Belongs to the binding-protein-dependent transport system permease family
WI24_RS09370	COG1879	ABC-type sugar transport system periplasmic component
WI24_RS09395	COG2375	cellular response to nickel ion
WI24_RS09395	COG1132	(ABC) transporter
WI24_RS09415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WI24_RS09425	COG1309	transcriptional regulator
WI24_RS09430	COG0739	heme binding
WI24_RS09435	COG0765	amino acid transport
WI24_RS09440	COG4597	amino acid ABC transporter
WI24_RS09445	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
WI24_RS09490	COG4964	Belongs to the GSP D family
WI24_RS09515	COG0477	Major facilitator Superfamily
WI24_RS09520	COG2719	SpoVR family
WI24_RS09525	COG2718	Belongs to the UPF0229 family
WI24_RS09530	COG2766	serine protein kinase
WI24_RS09535	COG0840	transmembrane signaling receptor activity
WI24_RS09540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WI24_RS09545	COG1609	Transcriptional regulator
WI24_RS09550	COG1172	Belongs to the binding-protein-dependent transport system permease family
WI24_RS09560	COG1879	ABC-type sugar transport system periplasmic component
WI24_RS09570	COG0583	DNA-binding transcription factor activity
WI24_RS09575	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WI24_RS09580	COG4208	sulfate ABC transporter
WI24_RS09585	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WI24_RS09590	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WI24_RS09630	COG0701	Predicted permease
WI24_RS09635	COG0667	Aldo Keto reductase
WI24_RS09655	COG1301	dicarboxylic acid transport
WI24_RS09690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WI24_RS09755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WI24_RS09760	COG0765	amino acid transport
WI24_RS09765	COG0673	inositol 2-dehydrogenase activity
WI24_RS09770	COG1802	Transcriptional regulator
WI24_RS09780	COG3023	N-Acetylmuramoyl-L-alanine amidase
WI24_RS09790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WI24_RS09795	COG0557	exoribonuclease II activity
WI24_RS09810	COG0840	transmembrane signaling receptor activity
WI24_RS09830	COG0519	Catalyzes the synthesis of GMP from XMP
WI24_RS09835	COG2814	Major facilitator Superfamily
WI24_RS09845	COG0318	PFAM AMP-dependent synthetase and ligase
WI24_RS09910	COG4964	Belongs to the GSP D family
WI24_RS09965	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WI24_RS09970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WI24_RS09975	COG0508	dehydrogenase complex catalyzes the overall conversion of
WI24_RS09980	COG0567	Dehydrogenase, E1 component
WI24_RS09985	COG1217	gtp-binding protein TYPA
WI24_RS09990	COG1846	Transcriptional regulator
WI24_RS10000	COG1566	PFAM secretion protein HlyD family protein
WI24_RS10005	COG2814	Major facilitator Superfamily
WI24_RS10010	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WI24_RS10025	COG0195	Participates in both transcription termination and antitermination
WI24_RS10025	COG2251	uridine kinase activity
WI24_RS10035	COG1187	pseudouridine synthase activity
WI24_RS10040	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WI24_RS10045	COG0583	DNA-binding transcription factor activity
WI24_RS10085	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WI24_RS10130	COG0776	regulation of translation
WI24_RS10155	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WI24_RS10170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WI24_RS10175	COG0251	oxidation-reduction process
WI24_RS10195	COG0583	DNA-binding transcription factor activity
WI24_RS10210	COG1028	Short-chain dehydrogenase reductase Sdr
WI24_RS10245	COG1028	Short-chain dehydrogenase reductase Sdr
WI24_RS10260	COG0477	Major facilitator Superfamily
WI24_RS10275	COG1295	ribonuclease BN
WI24_RS10290	COG0277	FAD linked oxidase domain protein
WI24_RS10305	COG0583	DNA-binding transcription factor activity
WI24_RS10335	COG0840	transmembrane signaling receptor activity
WI24_RS10340	COG2223	nitrite transmembrane transporter activity
WI24_RS10345	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WI24_RS10350	COG0210	DNA helicase
WI24_RS10355	COG0525	valine-tRNA ligase activity
WI24_RS10360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WI24_RS10370	COG5002	protein histidine kinase activity
WI24_RS10380	COG0745	RESPONSE REGULATOR receiver
WI24_RS10390	COG0425	Belongs to the sulfur carrier protein TusA family
WI24_RS10395	COG0673	inositol 2-dehydrogenase activity
WI24_RS10400	COG0673	inositol 2-dehydrogenase activity
WI24_RS10415	COG1172	Belongs to the binding-protein-dependent transport system permease family
WI24_RS10430	COG3962	Belongs to the TPP enzyme family
WI24_RS10440	COG3718	enzyme involved in inositol metabolism
WI24_RS10460	COG0824	Thioesterase
WI24_RS10475	COG0494	nUDIX hydrolase
WI24_RS10480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WI24_RS10490	COG0477	Major facilitator Superfamily
WI24_RS10505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WI24_RS10520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WI24_RS10525	COG1051	belongs to the nudix hydrolase family
WI24_RS10550	COG3511	phospholipase C
WI24_RS10570	COG2197	response regulator
WI24_RS10615	COG0583	DNA-binding transcription factor activity
WI24_RS10620	COG2814	Major facilitator Superfamily
WI24_RS10640	COG2801	Transposase and inactivated derivatives
WI24_RS10645	COG2963	transposase activity
WI24_RS10670	COG2801	Transposase and inactivated derivatives
WI24_RS10675	COG2963	transposase activity
WI24_RS10680	COG3328	transposase activity
WI24_RS10820	COG2916	Histone family protein nucleoid-structuring protein H-NS
WI24_RS10830	COG0583	DNA-binding transcription factor activity
WI24_RS10840	COG2135	peptidase activity
WI24_RS10875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WI24_RS10875	COG2755	lipolytic protein G-D-S-L family
WI24_RS10925	COG0582	viral genome integration into host DNA
WI24_RS10950	COG4942	peptidase
WI24_RS10955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WI24_RS10970	COG0534	Mate efflux family protein
WI24_RS11020	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WI24_RS11025	COG5002	protein histidine kinase activity
WI24_RS11030	COG0745	RESPONSE REGULATOR receiver
WI24_RS11045	COG0581	inorganic phosphate transmembrane transporter activity
WI24_RS11050	COG0573	inorganic phosphate transmembrane transporter activity
WI24_RS11055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WI24_RS11065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
WI24_RS11070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WI24_RS11080	COG1534	Rna-binding protein
WI24_RS11090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WI24_RS11095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WI24_RS11105	COG0505	Belongs to the CarA family
WI24_RS11125	COG0741	lytic transglycosylase activity
WI24_RS11125	COG1388	LysM domain
WI24_RS11130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WI24_RS11135	COG2226	methyltransferase
WI24_RS11140	COG0328	RNA-DNA hybrid ribonuclease activity
WI24_RS11145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WI24_RS11155	COG0477	Major facilitator Superfamily
WI24_RS11170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WI24_RS11180	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
WI24_RS11200	COG3052	prosthetic group binding
WI24_RS11220	COG0583	DNA-binding transcription factor activity
WI24_RS11225	COG1250	3-hydroxyacyl-CoA dehydrogenase
WI24_RS11230	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
WI24_RS11240	COG0071	Belongs to the small heat shock protein (HSP20) family
WI24_RS11260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WI24_RS11285	COG0583	DNA-binding transcription factor activity
WI24_RS11315	COG3706	GGDEF domain
WI24_RS11345	COG1609	Transcriptional regulator
WI24_RS11350	COG1840	ABC-type Fe3 transport system, periplasmic component
WI24_RS11355	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WI24_RS11370	COG1177	transmembrane transport
WI24_RS11375	COG3842	ATPase activity
WI24_RS11380	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WI24_RS11385	COG2814	Major facilitator Superfamily
WI24_RS11390	COG0697	spore germination
WI24_RS11400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WI24_RS11405	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
WI24_RS11435	COG0697	spore germination
WI24_RS11440	COG2200	EAL domain
WI24_RS11450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WI24_RS11455	COG1074	ATP-dependent DNA helicase activity
WI24_RS11460	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WI24_RS11480	COG1840	ABC-type Fe3 transport system, periplasmic component
WI24_RS11490	COG3842	ATPase activity
WI24_RS11495	COG1522	sequence-specific DNA binding
WI24_RS11510	COG1959	2 iron, 2 sulfur cluster binding
WI24_RS11535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WI24_RS11540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WI24_RS11565	COG2863	cytochrome
WI24_RS11570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WI24_RS11585	COG2010	Cytochrome c
WI24_RS11585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WI24_RS11590	COG2863	cytochrome
WI24_RS11620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WI24_RS11635	COG0006	proline dipeptidase activity
WI24_RS11640	COG2801	Transposase and inactivated derivatives
WI24_RS11645	COG2963	transposase activity
WI24_RS11650	COG2801	Transposase and inactivated derivatives
WI24_RS11660	COG2801	Transposase and inactivated derivatives
WI24_RS11710	COG2866	Carboxypeptidase
WI24_RS11725	COG0436	Aminotransferase
WI24_RS11730	COG0625	glutathione transferase activity
WI24_RS11735	COG1024	Enoyl-CoA hydratase
WI24_RS11740	COG0588	phosphoglycerate mutase activity
WI24_RS11750	COG1960	acyl-CoA dehydrogenase activity
WI24_RS11765	COG2030	dehydratase
WI24_RS11765	COG1012	belongs to the aldehyde dehydrogenase family
WI24_RS11770	COG1960	acyl-CoA dehydrogenase activity
WI24_RS11775	COG1960	acyl-CoA dehydrogenase activity
WI24_RS11785	COG0494	nUDIX hydrolase
WI24_RS11795	COG1007	ATP synthesis coupled electron transport
WI24_RS11830	COG1034	ATP synthesis coupled electron transport
WI24_RS11840	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WI24_RS11875	COG0149	triose-phosphate isomerase activity
WI24_RS11880	COG3321	synthase
WI24_RS11880	COG4221	oxidoreductase activity
WI24_RS11880	COG0604	alcohol dehydrogenase
WI24_RS11880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WI24_RS11895	COG0683	leucine binding
WI24_RS11905	COG0288	reversible hydration of carbon dioxide
WI24_RS11910	COG0659	secondary active sulfate transmembrane transporter activity
WI24_RS11920	COG1183	phosphatidylcholine synthase activity
WI24_RS11940	COG0028	Belongs to the TPP enzyme family
WI24_RS11970	COG0438	transferase activity, transferring glycosyl groups
WI24_RS11990	COG1028	Short-chain dehydrogenase reductase Sdr
WI24_RS11995	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WI24_RS12005	COG0154	amidase activity
WI24_RS12015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WI24_RS12035	COG2076	Multidrug Resistance protein
WI24_RS12045	COG0745	RESPONSE REGULATOR receiver
WI24_RS12050	COG2205	protein histidine kinase activity
WI24_RS12065	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
WI24_RS12070	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
WI24_RS12090	COG1028	Short-chain dehydrogenase reductase Sdr
WI24_RS12105	COG0151	Belongs to the GarS family
WI24_RS12120	COG0799	negative regulation of ribosome biogenesis
WI24_RS12215	COG4626	Terminase
WI24_RS12215	COG1802	Transcriptional regulator
WI24_RS12265	COG2233	PERMEase
WI24_RS12310	COG1595	DNA-templated transcription, initiation
WI24_RS12315	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WI24_RS12345	COG0859	PFAM glycosyl transferase family 9
WI24_RS12385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WI24_RS12390	COG0513	Belongs to the DEAD box helicase family
WI24_RS12415	COG1674	ftsk spoiiie
WI24_RS12420	COG2706	6-phosphogluconolactonase activity
WI24_RS12425	COG3387	PFAM Glycoside hydrolase 15-related
WI24_RS12435	COG1309	transcriptional regulator
WI24_RS12440	COG2878	Part of a membrane complex involved in electron transport
WI24_RS12445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WI24_RS12480	COG3135	benzoate transporter
WI24_RS12495	COG2764	glyoxalase bleomycin resistance protein dioxygenase
WI24_RS12540	COG0697	spore germination
WI24_RS12545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WI24_RS12585	COG0583	DNA-binding transcription factor activity
WI24_RS12605	COG0488	(ABC) transporter
WI24_RS12615	COG1773	rubredoxin
WI24_RS12635	COG0582	viral genome integration into host DNA
WI24_RS12705	COG4626	Terminase
WI24_RS12705	COG1802	Transcriptional regulator
WI24_RS12745	COG2801	Transposase and inactivated derivatives
WI24_RS12750	COG2963	transposase activity
WI24_RS12785	COG4574	serine-type endopeptidase inhibitor activity
WI24_RS12805	COG1881	PFAM PEBP family protein
WI24_RS12810	COG2814	Major facilitator Superfamily
WI24_RS12830	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
WI24_RS12850	COG1116	anion transmembrane transporter activity
WI24_RS12855	COG1176	ABC-type spermidine putrescine transport system, permease component I
WI24_RS12880	COG1741	Belongs to the pirin family
WI24_RS12890	COG4215	(ABC) transporter
WI24_RS12920	COG0347	Belongs to the P(II) protein family
WI24_RS12940	COG2827	Endonuclease containing a URI domain
WI24_RS12945	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WI24_RS12960	COG2271	Major facilitator Superfamily
WI24_RS12985	COG2226	methyltransferase
WI24_RS13020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WI24_RS13045	COG0489	protein tyrosine kinase activity
WI24_RS13050	COG3047	cAMP biosynthetic process
WI24_RS13050	COG2885	chlorophyll binding
WI24_RS13075	COG0729	surface antigen
WI24_RS13085	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
WI24_RS13105	COG0489	protein tyrosine kinase activity
WI24_RS13110	COG2259	Doxx family
WI24_RS13115	COG1492	cobalamin metabolic process
WI24_RS13125	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
WI24_RS13135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WI24_RS13145	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
WI24_RS13150	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
WI24_RS13155	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
WI24_RS13165	COG4206	TonB-dependent receptor
WI24_RS13200	COG0583	DNA-binding transcription factor activity
WI24_RS13230	COG0795	lipopolysaccharide-transporting ATPase activity
WI24_RS13245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WI24_RS13245	COG1648	precorrin-2 dehydrogenase activity
WI24_RS13250	COG2895	sulfate adenylyltransferase (ATP) activity
WI24_RS13260	COG0175	sulfate reduction
WI24_RS13275	COG0583	DNA-binding transcription factor activity
WI24_RS13285	COG0582	viral genome integration into host DNA
WI24_RS13360	COG2197	response regulator
WI24_RS13390	COG2205	protein histidine kinase activity
WI24_RS13390	COG0784	Response regulator, receiver
WI24_RS13395	COG1396	sequence-specific DNA binding
WI24_RS13400	COG0235	Class ii aldolase
WI24_RS13405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WI24_RS13410	COG2258	MOSC domain
WI24_RS13415	COG2267	carboxylic ester hydrolase activity
WI24_RS13425	COG0583	DNA-binding transcription factor activity
WI24_RS13445	COG1187	pseudouridine synthase activity
WI24_RS13460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WI24_RS13460	COG0543	2 iron, 2 sulfur cluster binding
WI24_RS13465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WI24_RS13470	COG0456	acetyltransferase
WI24_RS13505	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WI24_RS13510	COG1047	Peptidyl-prolyl cis-trans
WI24_RS13530	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WI24_RS13550	COG3264	Mechanosensitive ion channel
WI24_RS13550	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
WI24_RS13555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WI24_RS13555	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WI24_RS13560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WI24_RS13565	COG0196	riboflavin kinase activity
WI24_RS13600	COG1113	amino acid transport
WI24_RS13605	COG0542	response to heat
WI24_RS13615	COG1278	Cold shock
WI24_RS13645	COG0656	L-ascorbic acid biosynthetic process
WI24_RS13650	COG2188	Transcriptional regulator
WI24_RS13665	COG2814	Major facilitator Superfamily
WI24_RS13685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WI24_RS13710	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WI24_RS13715	COG1570	exodeoxyribonuclease VII activity
WI24_RS13750	COG0728	peptidoglycan biosynthetic process
WI24_RS13765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WI24_RS13785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WI24_RS13790	COG0318	PFAM AMP-dependent synthetase and ligase
WI24_RS13795	COG4974	Belongs to the 'phage' integrase family
WI24_RS13805	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WI24_RS13810	COG0802	atpase or kinase
WI24_RS13815	COG0860	N-Acetylmuramoyl-L-alanine amidase
WI24_RS13825	COG1741	Belongs to the pirin family
WI24_RS13830	COG3118	belongs to the thioredoxin family
WI24_RS13835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WI24_RS13845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WI24_RS13855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WI24_RS13865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WI24_RS13870	COG1522	sequence-specific DNA binding
WI24_RS13910	COG1012	belongs to the aldehyde dehydrogenase family
WI24_RS13920	COG0583	DNA-binding transcription factor activity
WI24_RS13925	COG0246	Mannitol dehydrogenase
WI24_RS13930	COG1070	Carbohydrate kinase
WI24_RS13935	COG2390	Transcriptional regulator
WI24_RS13950	COG0583	DNA-binding transcription factor activity
WI24_RS13960	COG3842	ATPase activity
WI24_RS13965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WI24_RS13975	COG1175	transmembrane transport
WI24_RS13990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WI24_RS14000	COG0735	belongs to the Fur family
WI24_RS14010	COG1121	(ABC) transporter
WI24_RS14015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WI24_RS14020	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
WI24_RS14035	COG1070	Carbohydrate kinase
WI24_RS14040	COG2233	PERMEase
WI24_RS14050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WI24_RS14055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WI24_RS14080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WI24_RS14110	COG0009	L-threonylcarbamoyladenylate synthase
WI24_RS14115	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WI24_RS14120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WI24_RS14125	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WI24_RS14135	COG0469	pyruvate kinase activity
WI24_RS14140	COG0126	phosphoglycerate kinase activity
WI24_RS14165	COG0859	PFAM glycosyl transferase family 9
WI24_RS14175	COG0429	hydrolase of the alpha beta-hydrolase fold
WI24_RS14185	COG4783	chaperone-mediated protein folding
WI24_RS14205	COG3307	-O-antigen
WI24_RS14210	COG4969	Belongs to the N-Me-Phe pilin family
WI24_RS14215	COG0861	Integral membrane protein TerC family
WI24_RS14220	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WI24_RS14235	COG2137	regulation of response to DNA damage stimulus
WI24_RS14240	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WI24_RS14290	COG0784	Response regulator, receiver
WI24_RS14290	COG2205	protein histidine kinase activity
WI24_RS14295	COG0583	DNA-binding transcription factor activity
WI24_RS14360	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
WI24_RS14375	COG0840	transmembrane signaling receptor activity
WI24_RS14405	COG4948	Mandelate Racemase Muconate Lactonizing
WI24_RS14430	COG0513	Belongs to the DEAD box helicase family
WI24_RS14475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WI24_RS14485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WI24_RS14490	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WI24_RS14500	COG2814	Major facilitator Superfamily
WI24_RS14505	COG0583	DNA-binding transcription factor activity
WI24_RS14515	COG1702	phosphate starvation-inducible protein PhoH
WI24_RS14525	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
WI24_RS14540	COG0815	Transfers the fatty acyl group on membrane lipoproteins
WI24_RS14545	COG0752	glycyl-tRNA synthetase alpha subunit
WI24_RS14550	COG0751	glycine-tRNA ligase activity
WI24_RS14555	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WI24_RS14560	COG0204	Acyl-transferase
WI24_RS14585	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WI24_RS14605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WI24_RS14610	COG5265	(ABC) transporter
WI24_RS14625	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WI24_RS14630	COG1024	Enoyl-CoA hydratase
WI24_RS14635	COG0183	Belongs to the thiolase family
WI24_RS14640	COG1024	Enoyl-CoA hydratase
WI24_RS14640	COG1250	3-hydroxyacyl-CoA dehydrogenase
WI24_RS14645	COG1960	acyl-CoA dehydrogenase activity
WI24_RS14660	COG0494	nUDIX hydrolase
WI24_RS14720	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WI24_RS14735	COG0251	oxidation-reduction process
WI24_RS14740	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
WI24_RS14765	COG0477	Major facilitator Superfamily
WI24_RS14790	COG1596	polysaccharide export
WI24_RS14795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WI24_RS14810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WI24_RS14820	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WI24_RS14840	COG2204	response regulator
WI24_RS14875	COG5001	Diguanylate cyclase
WI24_RS14875	COG5002	protein histidine kinase activity
WI24_RS14880	COG0235	Class ii aldolase
WI24_RS14940	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WI24_RS14965	COG2801	Transposase and inactivated derivatives
WI24_RS14970	COG2963	transposase activity
WI24_RS14995	COG0412	Dienelactone hydrolase
WI24_RS15000	COG0629	single-stranded DNA binding
WI24_RS15005	COG2814	Major facilitator Superfamily
WI24_RS15030	COG1280	lysine exporter protein (LysE YggA)
WI24_RS15050	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WI24_RS15065	COG1137	ATPase activity
WI24_RS15070	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WI24_RS15075	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WI24_RS15100	COG1194	a g-specific adenine glycosylase
WI24_RS15130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WI24_RS15150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WI24_RS15160	COG0742	ribosomal rna small subunit methyltransferase
WI24_RS15175	COG0625	glutathione transferase activity
WI24_RS15180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WI24_RS15190	COG0243	molybdopterin cofactor binding
WI24_RS15195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WI24_RS15205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WI24_RS15215	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WI24_RS15220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WI24_RS15235	COG1294	oxidase, subunit
WI24_RS15265	COG1263	PTS System
WI24_RS15265	COG2190	(PTS) system
WI24_RS15265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WI24_RS15270	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WI24_RS15270	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WI24_RS15275	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WI24_RS15280	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WI24_RS15285	COG2188	Transcriptional regulator
WI24_RS15290	COG0587	DNA-directed DNA polymerase activity
WI24_RS15305	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WI24_RS15325	COG0840	transmembrane signaling receptor activity
WI24_RS15335	COG1999	signal sequence binding
WI24_RS15345	COG1612	heme a metabolic process
WI24_RS15385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WI24_RS15400	COG2226	methyltransferase
WI24_RS15415	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
WI24_RS15435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WI24_RS15445	COG0793	Belongs to the peptidase S41A family
WI24_RS15450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WI24_RS15455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WI24_RS15460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WI24_RS15470	COG0189	ligase activity
WI24_RS15480	COG0004	ammonium transporteR
WI24_RS15490	COG2960	long-chain fatty acid transporting porin activity
WI24_RS15515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WI24_RS15520	COG2204	response regulator
WI24_RS15525	COG4191	Histidine kinase
WI24_RS15535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WI24_RS15545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WI24_RS15550	COG1960	acyl-CoA dehydrogenase activity
WI24_RS15555	COG1960	acyl-CoA dehydrogenase activity
WI24_RS15560	COG1024	Enoyl-CoA hydratase
WI24_RS15560	COG1250	3-hydroxyacyl-CoA dehydrogenase
WI24_RS15565	COG0583	DNA-binding transcription factor activity
WI24_RS15575	COG0405	Gamma-glutamyltransferase
WI24_RS15605	COG0583	DNA-binding transcription factor activity
WI24_RS15610	COG2921	Belongs to the UPF0250 family
WI24_RS15620	COG1686	Belongs to the peptidase S11 family
WI24_RS15650	COG1127	ABC transporter
WI24_RS15655	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WI24_RS15660	COG0737	Belongs to the 5'-nucleotidase family
WI24_RS15685	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WI24_RS15705	COG1024	Enoyl-CoA hydratase
WI24_RS15755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WI24_RS15760	COG0300	oxidoreductase activity
WI24_RS15765	COG1028	Short-chain dehydrogenase reductase Sdr
WI24_RS15780	COG0747	negative chemotaxis
WI24_RS15785	COG0488	(ABC) transporter
WI24_RS15800	COG0288	reversible hydration of carbon dioxide
WI24_RS15805	COG0183	Belongs to the thiolase family
WI24_RS15815	COG3012	SEC-C Motif Domain Protein
WI24_RS15845	COG3142	Participates in the control of copper homeostasis
WI24_RS15860	COG1785	Belongs to the alkaline phosphatase family
WI24_RS15875	COG2199	diguanylate cyclase activity
WI24_RS15875	COG2200	EAL domain
WI24_RS15880	COG0025	NhaP-type Na H and K H
WI24_RS15910	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WI24_RS15920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WI24_RS15925	COG0596	Alpha beta hydrolase
WI24_RS15950	COG3511	phospholipase C
WI24_RS15965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WI24_RS15995	COG0596	Alpha beta hydrolase
WI24_RS16005	COG0583	DNA-binding transcription factor activity
WI24_RS16010	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WI24_RS16030	COG0840	transmembrane signaling receptor activity
WI24_RS16035	COG1609	Transcriptional regulator
WI24_RS16085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WI24_RS16100	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WI24_RS16105	COG1704	LemA family
WI24_RS16115	COG2217	Heavy metal translocating P-type atpase
WI24_RS16160	COG0745	RESPONSE REGULATOR receiver
WI24_RS16180	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WI24_RS16190	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WI24_RS16195	COG0745	RESPONSE REGULATOR receiver
WI24_RS16200	COG5002	protein histidine kinase activity
WI24_RS16205	COG0745	RESPONSE REGULATOR receiver
WI24_RS16270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WI24_RS16280	COG2824	Alkylphosphonate utilization operon protein PhnA
WI24_RS16300	COG0583	DNA-binding transcription factor activity
WI24_RS16305	COG2233	PERMEase
WI24_RS16310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WI24_RS16320	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
WI24_RS16330	COG1706	bacterial-type flagellum-dependent cell motility
WI24_RS16335	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WI24_RS16355	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
WI24_RS16360	COG1558	bacterial-type flagellum-dependent cell motility
WI24_RS16365	COG1815	bacterial-type flagellum-dependent cell motility
WI24_RS16375	COG2747	anti-sigma28 factor FlgM
WI24_RS16400	COG0741	lytic transglycosylase activity
WI24_RS16405	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WI24_RS16415	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WI24_RS16420	COG1984	allophanate hydrolase subunit 2
WI24_RS16445	COG4608	Belongs to the ABC transporter superfamily
WI24_RS16450	COG0444	Belongs to the ABC transporter superfamily
WI24_RS16455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WI24_RS16460	COG0601	transmembrane transport
WI24_RS16465	COG0747	negative chemotaxis
WI24_RS16480	COG0579	oxidoreductase
WI24_RS16495	COG3568	Endonuclease Exonuclease Phosphatase
WI24_RS16500	COG1280	lysine exporter protein (LysE YggA)
WI24_RS16520	COG0531	amino acid
WI24_RS16535	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WI24_RS16595	COG1960	acyl-CoA dehydrogenase activity
WI24_RS16605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WI24_RS16610	COG2721	sulfolactate sulfo-lyase activity
WI24_RS16620	COG4948	Mandelate Racemase Muconate Lactonizing
WI24_RS16625	COG2271	Major facilitator Superfamily
WI24_RS16635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WI24_RS16640	COG0583	DNA-binding transcription factor activity
WI24_RS16655	COG2814	Major facilitator Superfamily
WI24_RS16675	COG0667	Aldo Keto reductase
WI24_RS16700	COG1560	Kdo2-lipid A biosynthetic process
WI24_RS16715	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WI24_RS16725	COG0523	cobalamin synthesis protein
WI24_RS16735	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WI24_RS16745	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
WI24_RS16770	COG1309	transcriptional regulator
WI24_RS16785	COG2814	Major facilitator Superfamily
WI24_RS16795	COG2207	Transcriptional regulator
WI24_RS16800	COG1064	alcohol dehydrogenase
WI24_RS16805	COG0708	Exodeoxyribonuclease III
WI24_RS16810	COG2326	polyphosphate kinase activity
WI24_RS16830	COG1077	Cell shape determining protein MreB Mrl
WI24_RS16845	COG0768	penicillin binding
WI24_RS16850	COG0772	Belongs to the SEDS family
WI24_RS16865	COG0720	synthase
WI24_RS16870	COG0602	queuosine metabolic process
WI24_RS16885	COG2204	response regulator
WI24_RS16890	COG5000	phosphorelay sensor kinase activity
WI24_RS16900	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WI24_RS16900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WI24_RS16920	COG0242	peptide deformylase activity
WI24_RS16925	COG0758	DNA mediated transformation
WI24_RS16940	COG0583	DNA-binding transcription factor activity
WI24_RS16945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WI24_RS16970	COG2801	Transposase and inactivated derivatives
WI24_RS16975	COG2963	transposase activity
WI24_RS17020	COG4695	Portal protein
WI24_RS17035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WI24_RS17050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WI24_RS17050	COG2169	Transcriptional regulator
WI24_RS17070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WI24_RS17175	COG3645	SOS response
WI24_RS17180	COG0582	viral genome integration into host DNA
WI24_RS17365	COG1012	belongs to the aldehyde dehydrogenase family
WI24_RS17920	COG4302	ethanolamine ammonia-lyase activity
WI24_RS18235	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WI24_RS18240	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WI24_RS18680	COG1333	cytochrome c biogenesis protein
WI24_RS18810	COG4178	(ABC) transporter
WI24_RS18880	COG2095	MarC family integral membrane protein
WI24_RS19575	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WI24_RS19580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WI24_RS19775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WI24_RS20120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WI24_RS20350	COG2353	YceI-like domain
WI24_RS20520	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WI24_RS20675	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WI24_RS20855	COG0156	8-amino-7-oxononanoate synthase activity
WI24_RS21115	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WI24_RS21365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
WI24_RS21625	COG2801	Transposase and inactivated derivatives
WI24_RS21660	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
WI24_RS21750	COG1126	abc transporter atp-binding protein
WI24_RS22260	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WI24_RS22380	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
WI24_RS22460	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WI24_RS22585	COG1530	ribonuclease E activity
WI24_RS22775	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
WI24_RS22935	COG0822	iron-sulfur transferase activity
WI24_RS22960	COG0719	Fe-S assembly protein
WI24_RS23925	COG2224	Isocitrate lyase
WI24_RS24350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WI24_RS24540	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WI24_RS24540	COG0047	phosphoribosylformylglycinamidine synthase activity
WI24_RS24720	COG3960	tartronate-semialdehyde synthase activity
WI24_RS25025	COG2183	response to ionizing radiation
WI24_RS25085	COG3243	poly(R)-hydroxyalkanoic acid synthase
WI24_RS25290	COG0038	chloride channel
WI24_RS25885	COG0739	heme binding
WI24_RS25990	COG2718	Belongs to the UPF0229 family
WI24_RS26055	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WI24_RS26100	COG0701	Predicted permease
WI24_RS26115	COG1301	dicarboxylic acid transport
WI24_RS26545	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WI24_RS26580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WI24_RS26740	COG0210	DNA helicase
WI24_RS26745	COG0210	DNA helicase
WI24_RS26995	COG2814	Major facilitator Superfamily
WI24_RS27155	COG0477	Major facilitator Superfamily
WI24_RS27850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WI24_RS27860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WI24_RS29560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WI24_RS29560	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons