locus-tag	class	description
WJ02_RS00010	COG0592	DNA-directed DNA polymerase activity
WJ02_RS00030	COG3328	transposase activity
WJ02_RS00055	COG3038	cytochrome b561
WJ02_RS00060	COG0753	catalase activity
WJ02_RS00090	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WJ02_RS00095	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WJ02_RS00100	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
WJ02_RS00130	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WJ02_RS00145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WJ02_RS00165	COG1987	bacterial-type flagellum assembly
WJ02_RS00195	COG1346	cytolysis
WJ02_RS00200	COG1380	Effector of murein hydrolase LrgA
WJ02_RS00205	COG0583	DNA-binding transcription factor activity
WJ02_RS00210	COG2814	Major facilitator Superfamily
WJ02_RS00260	COG2165	general secretion pathway protein
WJ02_RS00275	COG1459	type II secretion system
WJ02_RS00290	COG0741	lytic transglycosylase activity
WJ02_RS00295	COG0523	cobalamin synthesis protein
WJ02_RS00305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WJ02_RS00305	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
WJ02_RS00315	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
WJ02_RS00325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WJ02_RS00325	COG0519	Catalyzes the synthesis of GMP from XMP
WJ02_RS00330	COG1902	pentaerythritol trinitrate reductase activity
WJ02_RS00340	COG0642	Histidine kinase
WJ02_RS00355	COG2154	pterin-4-alpha-carbinolamine dehydratase
WJ02_RS00360	COG3186	Phenylalanine-4-hydroxylase
WJ02_RS00365	COG1522	sequence-specific DNA binding
WJ02_RS00375	COG0583	DNA-binding transcription factor activity
WJ02_RS00430	COG0445	tRNA wobble uridine modification
WJ02_RS00435	COG0357	Ribosomal RNA small subunit methyltransferase G
WJ02_RS00440	COG1192	Involved in chromosome partitioning
WJ02_RS00445	COG1475	DNA binding
WJ02_RS00450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WJ02_RS00460	COG0356	it plays a direct role in the translocation of protons across the membrane
WJ02_RS00475	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WJ02_RS00480	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WJ02_RS00485	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WJ02_RS00490	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WJ02_RS00495	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WJ02_RS00500	COG0318	PFAM AMP-dependent synthetase and ligase
WJ02_RS00510	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WJ02_RS00515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WJ02_RS00520	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WJ02_RS00520	COG0506	proline dehydrogenase activity
WJ02_RS00520	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WJ02_RS00525	COG0683	leucine binding
WJ02_RS00530	COG1960	acyl-CoA dehydrogenase activity
WJ02_RS00540	COG0436	Aminotransferase
WJ02_RS00545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WJ02_RS00550	COG0277	FAD linked oxidase domain protein
WJ02_RS00560	COG0789	Transcriptional regulator
WJ02_RS00575	COG0668	transmembrane transport
WJ02_RS00580	COG0531	amino acid
WJ02_RS00590	COG4302	ethanolamine ammonia-lyase activity
WJ02_RS00595	COG0583	DNA-binding transcription factor activity
WJ02_RS00600	COG0477	Major facilitator Superfamily
WJ02_RS00610	COG1012	belongs to the aldehyde dehydrogenase family
WJ02_RS00635	COG0028	Belongs to the TPP enzyme family
WJ02_RS00650	COG1760	l-serine dehydratase
WJ02_RS00660	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WJ02_RS00660	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WJ02_RS00665	COG0509	glycine decarboxylation via glycine cleavage system
WJ02_RS00670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WJ02_RS00680	COG0673	inositol 2-dehydrogenase activity
WJ02_RS00690	COG0210	DNA helicase
WJ02_RS00695	COG3245	cytochrome
WJ02_RS00715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WJ02_RS00735	COG1012	belongs to the aldehyde dehydrogenase family
WJ02_RS00740	COG0318	PFAM AMP-dependent synthetase and ligase
WJ02_RS00770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WJ02_RS00780	COG0519	Catalyzes the synthesis of GMP from XMP
WJ02_RS00795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WJ02_RS00800	COG2916	Histone family protein nucleoid-structuring protein H-NS
WJ02_RS00805	COG0438	transferase activity, transferring glycosyl groups
WJ02_RS00825	COG1360	Flagellar Motor Protein
WJ02_RS00830	COG0745	RESPONSE REGULATOR receiver
WJ02_RS00840	COG0835	chemotaxis
WJ02_RS00850	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WJ02_RS00855	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
WJ02_RS00865	COG0745	RESPONSE REGULATOR receiver
WJ02_RS00870	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WJ02_RS00890	COG3152	Membrane
WJ02_RS00895	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WJ02_RS00900	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WJ02_RS00925	COG1950	PFAM Membrane protein of
WJ02_RS00930	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
WJ02_RS00970	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WJ02_RS00975	COG1522	sequence-specific DNA binding
WJ02_RS00985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WJ02_RS01000	COG0792	nuclease activity
WJ02_RS01005	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WJ02_RS01010	COG2823	Periplasmic or secreted lipoprotein
WJ02_RS01035	COG2271	Major facilitator Superfamily
WJ02_RS01045	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
WJ02_RS01050	COG0577	efflux transmembrane transporter activity
WJ02_RS01060	COG1136	(ABC) transporter
WJ02_RS01075	COG2084	Dehydrogenase
WJ02_RS01080	COG1280	lysine exporter protein (LysE YggA)
WJ02_RS01085	COG2814	Major facilitator Superfamily
WJ02_RS01090	COG0583	DNA-binding transcription factor activity
WJ02_RS01110	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WJ02_RS01120	COG1881	PFAM PEBP family protein
WJ02_RS01125	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WJ02_RS01130	COG0280	phosphate acetyltransferase
WJ02_RS01130	COG0281	malic enzyme
WJ02_RS01150	COG1522	sequence-specific DNA binding
WJ02_RS01170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WJ02_RS01175	COG2151	metal-sulfur cluster biosynthetic enzyme
WJ02_RS01180	COG3396	Phenylacetate-CoA oxygenase
WJ02_RS01185	COG3460	Phenylacetate-CoA oxygenase
WJ02_RS01190	COG3396	Phenylacetate-CoA oxygenase
WJ02_RS01240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WJ02_RS01250	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WJ02_RS01260	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WJ02_RS01265	COG0081	regulation of translation
WJ02_RS01275	COG0222	ribosome binding
WJ02_RS01280	COG0085	RNA polymerase activity
WJ02_RS01285	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WJ02_RS01290	COG0514	ATP-dependent DNA helicase (RecQ)
WJ02_RS01310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WJ02_RS01320	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WJ02_RS01335	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WJ02_RS01365	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
WJ02_RS01370	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WJ02_RS01380	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WJ02_RS01385	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WJ02_RS01395	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WJ02_RS01415	COG0200	Binds to the 23S rRNA
WJ02_RS01420	COG0201	protein transport
WJ02_RS01435	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WJ02_RS01445	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WJ02_RS01465	COG4232	protein-disulfide reductase activity
WJ02_RS01475	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WJ02_RS01485	COG1333	cytochrome c biogenesis protein
WJ02_RS01490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WJ02_RS01495	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WJ02_RS01500	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
WJ02_RS01510	COG1965	Belongs to the frataxin family
WJ02_RS01545	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WJ02_RS01550	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WJ02_RS01555	COG1653	transport
WJ02_RS01560	COG1175	transmembrane transport
WJ02_RS01565	COG0395	ABC-type sugar transport system, permease component
WJ02_RS01575	COG0584	glycerophosphoryl diester phosphodiesterase
WJ02_RS01590	COG0067	glutamate synthase
WJ02_RS01590	COG0069	glutamate synthase activity
WJ02_RS01590	COG0070	glutamate synthase
WJ02_RS01610	COG4178	(ABC) transporter
WJ02_RS01635	COG1127	ABC transporter
WJ02_RS01640	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WJ02_RS01645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WJ02_RS01665	COG1131	(ABC) transporter
WJ02_RS01670	COG0842	Transport permease protein
WJ02_RS01685	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WJ02_RS01700	COG0131	Imidazoleglycerol-phosphate dehydratase
WJ02_RS01705	COG2095	MarC family integral membrane protein
WJ02_RS01710	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WJ02_RS01715	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
WJ02_RS01720	COG0107	imidazoleglycerol-phosphate synthase activity
WJ02_RS01725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WJ02_RS01730	COG0140	phosphoribosyl-ATP diphosphatase activity
WJ02_RS01745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WJ02_RS01750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WJ02_RS01755	COG0805	protein transport
WJ02_RS01760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WJ02_RS01765	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WJ02_RS01770	COG0723	plastoquinol--plastocyanin reductase activity
WJ02_RS01775	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WJ02_RS01780	COG2857	Cytochrome c1
WJ02_RS01785	COG0625	glutathione transferase activity
WJ02_RS01790	COG2969	positive regulation of protein catabolic process
WJ02_RS01825	COG1401	restriction endodeoxyribonuclease activity
WJ02_RS01835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WJ02_RS01850	COG3328	transposase activity
WJ02_RS01975	COG0308	aminopeptidase N
WJ02_RS02000	COG1309	transcriptional regulator
WJ02_RS02020	COG0443	Heat shock 70 kDa protein
WJ02_RS02025	COG1278	Cold shock
WJ02_RS02030	COG0531	amino acid
WJ02_RS02035	COG3384	dioxygenase
WJ02_RS02045	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WJ02_RS02050	COG2890	protein-(glutamine-N5) methyltransferase activity
WJ02_RS02055	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WJ02_RS02060	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
WJ02_RS02075	COG0006	proline dipeptidase activity
WJ02_RS02080	COG1335	isochorismatase
WJ02_RS02090	COG0488	(ABC) transporter
WJ02_RS02105	COG0012	GTP binding
WJ02_RS02110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WJ02_RS02115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WJ02_RS02130	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WJ02_RS02140	COG0134	indole-3-glycerol-phosphate synthase activity
WJ02_RS02145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WJ02_RS02150	COG0512	Glutamine amidotransferase of anthranilate synthase
WJ02_RS02165	COG0546	phosphoglycolate phosphatase activity
WJ02_RS02170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WJ02_RS02175	COG2967	ApaG domain
WJ02_RS02180	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WJ02_RS02190	COG2050	protein possibly involved in aromatic compounds catabolism
WJ02_RS02195	COG1024	Enoyl-CoA hydratase
WJ02_RS02210	COG1024	Enoyl-CoA hydratase
WJ02_RS02240	COG0243	molybdopterin cofactor binding
WJ02_RS02245	COG0318	PFAM AMP-dependent synthetase and ligase
WJ02_RS02250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WJ02_RS02255	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
WJ02_RS02260	COG2001	Belongs to the MraZ family
WJ02_RS02265	COG0275	rRNA processing
WJ02_RS02270	COG3116	cell division
WJ02_RS02280	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WJ02_RS02285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WJ02_RS02290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WJ02_RS02295	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WJ02_RS02305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WJ02_RS02310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WJ02_RS02315	COG1181	Belongs to the D-alanine--D-alanine ligase family
WJ02_RS02320	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WJ02_RS02335	COG0678	peroxiredoxin activity
WJ02_RS02340	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WJ02_RS02350	COG0653	protein targeting
WJ02_RS02365	COG0494	nUDIX hydrolase
WJ02_RS02370	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
WJ02_RS02375	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
WJ02_RS02385	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WJ02_RS02400	COG4536	flavin adenine dinucleotide binding
WJ02_RS02415	COG0142	geranyltranstransferase activity
WJ02_RS02430	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WJ02_RS02435	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
WJ02_RS02445	COG0494	nUDIX hydrolase
WJ02_RS02450	COG0442	prolyl-tRNA aminoacylation
WJ02_RS02455	COG2095	MarC family integral membrane protein
WJ02_RS02460	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
WJ02_RS02465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WJ02_RS02505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WJ02_RS02510	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
WJ02_RS02520	COG2264	protein methyltransferase activity
WJ02_RS02525	COG0439	Biotin carboxylase
WJ02_RS02530	COG0511	ligase activity, forming carbon-carbon bonds
WJ02_RS02535	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WJ02_RS02540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WJ02_RS02550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WJ02_RS02555	COG3150	esterase
WJ02_RS02560	COG0557	exoribonuclease II activity
WJ02_RS02565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WJ02_RS02570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WJ02_RS02585	COG1414	Transcriptional regulator
WJ02_RS02590	COG3734	2-keto-3-deoxy-galactonokinase
WJ02_RS02595	COG0800	Aldolase
WJ02_RS02600	COG1028	Short-chain dehydrogenase reductase Sdr
WJ02_RS02610	COG1129	ABC transporter
WJ02_RS02630	COG0284	orotidine-5'-phosphate decarboxylase activity
WJ02_RS02635	COG1546	Belongs to the CinA family
WJ02_RS02640	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WJ02_RS02655	COG4290	ribonuclease
WJ02_RS02665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WJ02_RS02675	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WJ02_RS02680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WJ02_RS02685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WJ02_RS02695	COG1301	dicarboxylic acid transport
WJ02_RS02700	COG4266	Belongs to the allantoicase family
WJ02_RS02705	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
WJ02_RS02710	COG0735	belongs to the Fur family
WJ02_RS02715	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WJ02_RS02720	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WJ02_RS02735	COG0495	leucyl-tRNA aminoacylation
WJ02_RS02740	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
WJ02_RS02745	COG1466	dna polymerase III delta subunit
WJ02_RS02750	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
WJ02_RS02755	COG1981	membrane
WJ02_RS02770	COG0800	Aldolase
WJ02_RS02780	COG3265	gluconokinase activity
WJ02_RS02790	COG0583	DNA-binding transcription factor activity
WJ02_RS02800	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WJ02_RS02810	COG0765	amino acid transport
WJ02_RS02815	COG0765	amino acid transport
WJ02_RS02820	COG1126	abc transporter atp-binding protein
WJ02_RS02830	COG0121	glutamine amidotransferase
WJ02_RS02835	COG0418	dihydroorotase activity
WJ02_RS02860	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WJ02_RS02865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WJ02_RS02870	COG0316	Belongs to the HesB IscA family
WJ02_RS02875	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WJ02_RS02885	COG1490	D-aminoacyl-tRNA deacylase activity
WJ02_RS02890	COG0588	phosphoglycerate mutase activity
WJ02_RS02900	COG2255	four-way junction helicase activity
WJ02_RS02905	COG0632	four-way junction helicase activity
WJ02_RS02910	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
WJ02_RS02915	COG0138	bifunctional purine biosynthesis protein purh
WJ02_RS02920	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
WJ02_RS02930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WJ02_RS02935	COG0006	proline dipeptidase activity
WJ02_RS02940	COG0625	glutathione transferase activity
WJ02_RS02945	COG0069	glutamate synthase activity
WJ02_RS02950	COG0482	sulfurtransferase activity
WJ02_RS03000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WJ02_RS03000	COG3008	intermembrane lipid transfer
WJ02_RS03005	COG2995	paraquat-inducible protein a
WJ02_RS03020	COG2353	YceI-like domain
WJ02_RS03025	COG2353	YceI-like domain
WJ02_RS03035	COG0793	Belongs to the peptidase S41A family
WJ02_RS03040	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WJ02_RS03045	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WJ02_RS03050	COG1862	Preprotein translocase
WJ02_RS03055	COG0343	queuine tRNA-ribosyltransferase activity
WJ02_RS03060	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WJ02_RS03065	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WJ02_RS03080	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
WJ02_RS03085	COG0783	Belongs to the Dps family
WJ02_RS03090	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WJ02_RS03105	COG0247	lactate metabolic process
WJ02_RS03110	COG0277	FAD linked oxidase domain protein
WJ02_RS03115	COG0277	FAD linked oxidase domain protein
WJ02_RS03120	COG0277	FAD linked oxidase domain protein
WJ02_RS03125	COG2096	Adenosyltransferase
WJ02_RS03130	COG1017	nitric oxide dioxygenase activity
WJ02_RS03130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WJ02_RS03135	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WJ02_RS03140	COG0312	modulator of DNA gyrase
WJ02_RS03145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WJ02_RS03155	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WJ02_RS03160	COG0497	DNA recombination
WJ02_RS03165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WJ02_RS03170	COG1420	regulation of RNA biosynthetic process
WJ02_RS03175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WJ02_RS03190	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WJ02_RS03200	COG0443	Heat shock 70 kDa protein
WJ02_RS03205	COG0484	heat shock protein binding
WJ02_RS03215	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WJ02_RS03225	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WJ02_RS03230	COG0617	tRNA 3'-terminal CCA addition
WJ02_RS03240	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WJ02_RS03245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WJ02_RS03255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WJ02_RS03260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WJ02_RS03265	COG0586	Pfam SNARE associated Golgi protein
WJ02_RS03270	COG0529	Catalyzes the synthesis of activated sulfate
WJ02_RS03280	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WJ02_RS03300	COG0823	Involved in the tonB-independent uptake of proteins
WJ02_RS03320	COG0824	Thioesterase
WJ02_RS03325	COG4221	oxidoreductase activity
WJ02_RS03335	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WJ02_RS03380	COG0450	alkyl hydroperoxide reductase
WJ02_RS03385	COG1960	acyl-CoA dehydrogenase activity
WJ02_RS03405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WJ02_RS03415	COG2814	Major facilitator Superfamily
WJ02_RS03420	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
WJ02_RS03435	COG2814	Major facilitator Superfamily
WJ02_RS03440	COG0778	Nitroreductase
WJ02_RS03445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WJ02_RS03450	COG0583	DNA-binding transcription factor activity
WJ02_RS03455	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WJ02_RS03460	COG4977	sequence-specific DNA binding
WJ02_RS03480	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WJ02_RS03530	COG0730	response to heat
WJ02_RS03585	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WJ02_RS03590	COG0459	protein refolding
WJ02_RS03605	COG1773	rubredoxin
WJ02_RS03615	COG1678	Uncharacterized ACR, COG1678
WJ02_RS03620	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WJ02_RS03625	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
WJ02_RS03630	COG0540	Belongs to the ATCase OTCase family
WJ02_RS03635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
WJ02_RS03675	COG0662	Cupin 2, conserved barrel domain protein
WJ02_RS03675	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
WJ02_RS03690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WJ02_RS03700	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
WJ02_RS03730	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WJ02_RS03730	COG0546	phosphoglycolate phosphatase activity
WJ02_RS03740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WJ02_RS03760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WJ02_RS03765	COG0438	transferase activity, transferring glycosyl groups
WJ02_RS03800	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WJ02_RS03805	COG0830	nickel cation binding
WJ02_RS03810	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
WJ02_RS03815	COG0804	urea catabolic process
WJ02_RS03820	COG0832	Belongs to the urease beta subunit family
WJ02_RS03830	COG0829	nickel cation binding
WJ02_RS03840	COG1129	ABC transporter
WJ02_RS03865	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WJ02_RS03875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WJ02_RS03890	COG1968	undecaprenyl-diphosphatase activity
WJ02_RS03895	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WJ02_RS03955	COG0494	nUDIX hydrolase
WJ02_RS03965	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
WJ02_RS03975	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WJ02_RS03985	COG0762	integral membrane protein
WJ02_RS04005	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WJ02_RS04015	COG0436	Aminotransferase
WJ02_RS04020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WJ02_RS04025	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WJ02_RS04045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WJ02_RS04045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WJ02_RS04050	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WJ02_RS04060	COG2814	Major facilitator Superfamily
WJ02_RS04070	COG0363	glucosamine-6-phosphate deaminase activity
WJ02_RS04075	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WJ02_RS04085	COG1175	transmembrane transport
WJ02_RS04090	COG0395	ABC-type sugar transport system, permease component
WJ02_RS04095	COG3842	ATPase activity
WJ02_RS04100	COG2860	membrane
WJ02_RS04105	COG1193	negative regulation of DNA recombination
WJ02_RS04110	COG0492	ferredoxin-NADP+ reductase activity
WJ02_RS04115	COG1674	ftsk spoiiie
WJ02_RS04120	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WJ02_RS04125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WJ02_RS04135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WJ02_RS04160	COG0850	regulation of cytokinetic process
WJ02_RS04165	COG2894	cell division
WJ02_RS04170	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WJ02_RS04185	COG0859	PFAM glycosyl transferase family 9
WJ02_RS04195	COG0477	Major facilitator Superfamily
WJ02_RS04220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WJ02_RS04225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WJ02_RS04230	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
WJ02_RS04235	COG1561	YicC-like family, N-terminal region
WJ02_RS04250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WJ02_RS04275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WJ02_RS04285	COG1278	Cold shock
WJ02_RS04290	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WJ02_RS04290	COG1199	ATP-dependent helicase activity
WJ02_RS04305	COG4772	TonB-dependent receptor
WJ02_RS04330	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
WJ02_RS04335	COG0308	aminopeptidase N
WJ02_RS04345	COG2119	membrane
WJ02_RS04350	COG0402	S-adenosylhomocysteine deaminase activity
WJ02_RS04355	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WJ02_RS04380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WJ02_RS04415	COG3383	formate dehydrogenase (NAD+) activity
WJ02_RS04430	COG1910	domain protein
WJ02_RS04450	COG0546	phosphoglycolate phosphatase activity
WJ02_RS04455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WJ02_RS04475	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WJ02_RS04485	COG0287	Prephenate dehydrogenase
WJ02_RS04490	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WJ02_RS04495	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WJ02_RS04505	COG0776	regulation of translation
WJ02_RS04515	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WJ02_RS04525	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WJ02_RS04530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WJ02_RS04545	COG2951	lytic endotransglycosylase activity
WJ02_RS04550	COG0123	including yeast histone deacetylase and acetoin utilization protein
WJ02_RS04555	COG2267	carboxylic ester hydrolase activity
WJ02_RS04560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WJ02_RS04565	COG2011	ABC-type metal ion transport system permease component
WJ02_RS04585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WJ02_RS04615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WJ02_RS04620	COG0336	Belongs to the RNA methyltransferase TrmD family
WJ02_RS04625	COG0335	large ribosomal subunit rRNA binding
WJ02_RS04650	COG0501	Belongs to the peptidase M48B family
WJ02_RS04655	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
WJ02_RS04660	COG0521	Mo-molybdopterin cofactor biosynthetic process
WJ02_RS04665	COG3028	Belongs to the UPF0307 family
WJ02_RS04670	COG0312	modulator of DNA gyrase
WJ02_RS04675	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
WJ02_RS04685	COG2204	response regulator
WJ02_RS04690	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WJ02_RS04715	COG0114	fumarate hydratase activity
WJ02_RS04725	COG2501	S4 domain
WJ02_RS04745	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
WJ02_RS04755	COG3045	CreA protein
WJ02_RS04770	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WJ02_RS04775	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WJ02_RS04795	COG1322	Protein conserved in bacteria
WJ02_RS04810	COG0303	'Molybdopterin
WJ02_RS04815	COG0746	molybdenum cofactor guanylyltransferase activity
WJ02_RS04820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WJ02_RS04825	COG1530	ribonuclease E activity
WJ02_RS04835	COG0546	phosphoglycolate phosphatase activity
WJ02_RS04845	COG0616	signal peptide processing
WJ02_RS04860	COG1399	metal-binding, possibly nucleic acid-binding protein
WJ02_RS04870	COG0416	fatty acid biosynthetic process
WJ02_RS04875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WJ02_RS04895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WJ02_RS04905	COG1595	DNA-templated transcription, initiation
WJ02_RS04920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WJ02_RS04930	COG0481	GTPase activity
WJ02_RS04935	COG0681	Belongs to the peptidase S26 family
WJ02_RS04940	COG0571	ribonuclease III activity
WJ02_RS04945	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WJ02_RS04955	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WJ02_RS04965	COG1472	Belongs to the glycosyl hydrolase 3 family
WJ02_RS04975	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WJ02_RS04985	COG0322	excinuclease ABC activity
WJ02_RS05030	COG3039	Transposase
WJ02_RS05065	COG0024	Methionine aminopeptidase
WJ02_RS05070	COG1956	GAF domain-containing protein
WJ02_RS05085	COG2153	protein acetylation
WJ02_RS05100	COG1999	signal sequence binding
WJ02_RS05110	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
WJ02_RS05115	COG1132	(ABC) transporter
WJ02_RS05120	COG0438	transferase activity, transferring glycosyl groups
WJ02_RS05150	COG3511	phospholipase C
WJ02_RS05160	COG0596	Alpha beta hydrolase
WJ02_RS05165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WJ02_RS05180	COG3394	polysaccharide catabolic process
WJ02_RS05230	COG1012	belongs to the aldehyde dehydrogenase family
WJ02_RS05235	COG3724	N-succinylarginine dihydrolase activity
WJ02_RS05285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WJ02_RS05295	COG0154	amidase activity
WJ02_RS05305	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WJ02_RS05320	COG0004	ammonium transporteR
WJ02_RS05335	COG1959	2 iron, 2 sulfur cluster binding
WJ02_RS05345	COG1522	sequence-specific DNA binding
WJ02_RS05350	COG1289	transmembrane transporter activity
WJ02_RS05355	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WJ02_RS05360	COG1074	ATP-dependent DNA helicase activity
WJ02_RS05365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WJ02_RS05375	COG2200	EAL domain
WJ02_RS05395	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
WJ02_RS05410	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
WJ02_RS05415	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WJ02_RS05420	COG0697	spore germination
WJ02_RS05425	COG2814	Major facilitator Superfamily
WJ02_RS05430	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WJ02_RS05435	COG3842	ATPase activity
WJ02_RS05440	COG1177	transmembrane transport
WJ02_RS05450	COG1840	ABC-type Fe3 transport system, periplasmic component
WJ02_RS05455	COG1609	Transcriptional regulator
WJ02_RS05490	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WJ02_RS05495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WJ02_RS05505	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WJ02_RS05510	COG0583	DNA-binding transcription factor activity
WJ02_RS05515	COG0477	Major facilitator Superfamily
WJ02_RS05530	COG2814	Major facilitator Superfamily
WJ02_RS05535	COG0583	DNA-binding transcription factor activity
WJ02_RS05550	COG0583	DNA-binding transcription factor activity
WJ02_RS05555	COG1253	flavin adenine dinucleotide binding
WJ02_RS05575	COG0583	DNA-binding transcription factor activity
WJ02_RS05595	COG3052	prosthetic group binding
WJ02_RS05615	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
WJ02_RS05650	COG0477	Major facilitator Superfamily
WJ02_RS05655	COG1742	UPF0060 membrane protein
WJ02_RS05660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WJ02_RS05665	COG0328	RNA-DNA hybrid ribonuclease activity
WJ02_RS05670	COG2226	methyltransferase
WJ02_RS05675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WJ02_RS05680	COG0741	lytic transglycosylase activity
WJ02_RS05680	COG1388	LysM domain
WJ02_RS05685	COG2223	nitrite transmembrane transporter activity
WJ02_RS05690	COG0505	Belongs to the CarA family
WJ02_RS05700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WJ02_RS05705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WJ02_RS05715	COG1534	Rna-binding protein
WJ02_RS05720	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WJ02_RS05725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WJ02_RS05735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WJ02_RS05740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WJ02_RS05745	COG0573	inorganic phosphate transmembrane transporter activity
WJ02_RS05750	COG0581	inorganic phosphate transmembrane transporter activity
WJ02_RS05765	COG0745	RESPONSE REGULATOR receiver
WJ02_RS05775	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WJ02_RS05810	COG0534	Mate efflux family protein
WJ02_RS05820	COG4942	peptidase
WJ02_RS05940	COG4397	Mu-like prophage major head subunit gpT
WJ02_RS05950	COG4388	Caudovirus prohead serine protease
WJ02_RS05965	COG2369	cell adhesion
WJ02_RS05970	COG4383	Mu-like prophage protein gp29
WJ02_RS06085	COG2205	protein histidine kinase activity
WJ02_RS06090	COG0745	RESPONSE REGULATOR receiver
WJ02_RS06110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WJ02_RS06120	COG4589	Belongs to the CDS family
WJ02_RS06130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WJ02_RS06135	COG2267	carboxylic ester hydrolase activity
WJ02_RS06140	COG0671	phosphoesterase, PA-phosphatase related
WJ02_RS06140	COG2453	phosphatase
WJ02_RS06150	COG1215	transferase activity, transferring glycosyl groups
WJ02_RS06155	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
WJ02_RS06185	COG2194	sulfuric ester hydrolase activity
WJ02_RS06195	COG1741	Belongs to the pirin family
WJ02_RS06205	COG0025	NhaP-type Na H and K H
WJ02_RS06230	COG1858	cytochrome C peroxidase
WJ02_RS06245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WJ02_RS06260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WJ02_RS06265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WJ02_RS06275	COG0477	Major facilitator Superfamily
WJ02_RS06280	COG2816	NAD+ diphosphatase activity
WJ02_RS06285	COG0824	Thioesterase
WJ02_RS06310	COG1028	Short-chain dehydrogenase reductase Sdr
WJ02_RS06320	COG3718	enzyme involved in inositol metabolism
WJ02_RS06330	COG3962	Belongs to the TPP enzyme family
WJ02_RS06345	COG1129	ABC transporter
WJ02_RS06350	COG1172	Belongs to the binding-protein-dependent transport system permease family
WJ02_RS06355	COG0673	inositol 2-dehydrogenase activity
WJ02_RS06360	COG0673	inositol 2-dehydrogenase activity
WJ02_RS06365	COG1737	Transcriptional regulator
WJ02_RS06380	COG0425	Belongs to the sulfur carrier protein TusA family
WJ02_RS06390	COG0745	RESPONSE REGULATOR receiver
WJ02_RS06410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WJ02_RS06415	COG0525	valine-tRNA ligase activity
WJ02_RS06420	COG0210	DNA helicase
WJ02_RS06425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WJ02_RS06430	COG2223	nitrite transmembrane transporter activity
WJ02_RS06435	COG0840	transmembrane signaling receptor activity
WJ02_RS06460	COG0583	DNA-binding transcription factor activity
WJ02_RS06470	COG0277	FAD linked oxidase domain protein
WJ02_RS06485	COG1295	ribonuclease BN
WJ02_RS06500	COG0477	Major facilitator Superfamily
WJ02_RS06505	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WJ02_RS06515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WJ02_RS06520	COG2271	Major facilitator Superfamily
WJ02_RS06525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WJ02_RS06535	COG1028	Short-chain dehydrogenase reductase Sdr
WJ02_RS06560	COG1028	Short-chain dehydrogenase reductase Sdr
WJ02_RS06575	COG0583	DNA-binding transcription factor activity
WJ02_RS06585	COG0251	oxidation-reduction process
WJ02_RS06590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WJ02_RS06600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WJ02_RS06605	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WJ02_RS06620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WJ02_RS06630	COG0776	regulation of translation
WJ02_RS06645	COG4106	trans-aconitate 2-methyltransferase activity
WJ02_RS06660	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WJ02_RS06690	COG0583	DNA-binding transcription factor activity
WJ02_RS06695	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WJ02_RS06705	COG0779	Required for maturation of 30S ribosomal subunits
WJ02_RS06710	COG2251	uridine kinase activity
WJ02_RS06710	COG0195	Participates in both transcription termination and antitermination
WJ02_RS06715	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WJ02_RS06720	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WJ02_RS06730	COG2814	Major facilitator Superfamily
WJ02_RS06735	COG1566	PFAM secretion protein HlyD family protein
WJ02_RS06745	COG1846	Transcriptional regulator
WJ02_RS06750	COG1217	gtp-binding protein TYPA
WJ02_RS06755	COG0567	Dehydrogenase, E1 component
WJ02_RS06760	COG0508	dehydrogenase complex catalyzes the overall conversion of
WJ02_RS06765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WJ02_RS06770	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WJ02_RS06820	COG4964	Belongs to the GSP D family
WJ02_RS06885	COG0318	PFAM AMP-dependent synthetase and ligase
WJ02_RS06895	COG2814	Major facilitator Superfamily
WJ02_RS06915	COG1879	ABC-type sugar transport system periplasmic component
WJ02_RS06920	COG1172	Belongs to the binding-protein-dependent transport system permease family
WJ02_RS06930	COG1940	carbohydrate kinase activity
WJ02_RS06950	COG0557	exoribonuclease II activity
WJ02_RS06955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WJ02_RS06960	COG3023	N-Acetylmuramoyl-L-alanine amidase
WJ02_RS06965	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
WJ02_RS06970	COG1802	Transcriptional regulator
WJ02_RS06975	COG0673	inositol 2-dehydrogenase activity
WJ02_RS06980	COG0765	amino acid transport
WJ02_RS06985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WJ02_RS06990	COG0167	dihydroorotate dehydrogenase activity
WJ02_RS06995	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WJ02_RS07000	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WJ02_RS07015	COG4702	Belongs to the UPF0303 family
WJ02_RS07040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WJ02_RS07045	COG1116	anion transmembrane transporter activity
WJ02_RS07065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WJ02_RS07120	COG0667	Aldo Keto reductase
WJ02_RS07130	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
WJ02_RS07135	COG0701	Predicted permease
WJ02_RS07170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WJ02_RS07175	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WJ02_RS07180	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WJ02_RS07185	COG4208	sulfate ABC transporter
WJ02_RS07190	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WJ02_RS07195	COG0583	DNA-binding transcription factor activity
WJ02_RS07200	COG1879	ABC-type sugar transport system periplasmic component
WJ02_RS07205	COG1129	ABC transporter
WJ02_RS07210	COG1172	Belongs to the binding-protein-dependent transport system permease family
WJ02_RS07215	COG1609	Transcriptional regulator
WJ02_RS07220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WJ02_RS07230	COG2766	serine protein kinase
WJ02_RS07235	COG2718	Belongs to the UPF0229 family
WJ02_RS07240	COG2719	SpoVR family
WJ02_RS07245	COG0477	Major facilitator Superfamily
WJ02_RS07255	COG0739	heme binding
WJ02_RS07260	COG1309	transcriptional regulator
WJ02_RS07270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WJ02_RS07295	COG1120	ATPase activity
WJ02_RS07330	COG3486	L-lysine 6-monooxygenase (NADPH) activity
WJ02_RS07335	COG4774	siderophore transport
WJ02_RS07340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WJ02_RS07365	COG1473	amidohydrolase
WJ02_RS07370	COG1797	cobyrinic acid a,c-diamide synthase activity
WJ02_RS07390	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
WJ02_RS07415	COG1671	Belongs to the UPF0178 family
WJ02_RS07450	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
WJ02_RS07455	COG2099	Precorrin-6x reductase
WJ02_RS07465	COG2807	transmembrane transport
WJ02_RS07470	COG1846	Transcriptional regulator
WJ02_RS07475	COG0625	glutathione transferase activity
WJ02_RS07495	COG2070	2-Nitropropane dioxygenase
WJ02_RS07515	COG0531	amino acid
WJ02_RS07545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WJ02_RS07555	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
WJ02_RS07570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WJ02_RS07575	COG2801	Transposase and inactivated derivatives
WJ02_RS07590	COG0598	Magnesium transport protein CorA
WJ02_RS07635	COG1609	Transcriptional regulator
WJ02_RS07650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WJ02_RS07665	COG2855	membrane
WJ02_RS07670	COG0038	chloride channel
WJ02_RS07685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WJ02_RS07720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WJ02_RS07720	COG0730	response to heat
WJ02_RS07725	COG1177	transmembrane transport
WJ02_RS07730	COG1176	ABC-type spermidine putrescine transport system, permease component I
WJ02_RS07735	COG3842	ATPase activity
WJ02_RS07740	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WJ02_RS07750	COG3047	cAMP biosynthetic process
WJ02_RS07755	COG2070	2-Nitropropane dioxygenase
WJ02_RS07770	COG1522	sequence-specific DNA binding
WJ02_RS07780	COG0488	(ABC) transporter
WJ02_RS07785	COG2982	Protein involved in outer membrane biogenesis
WJ02_RS07790	COG3842	ATPase activity
WJ02_RS07795	COG0390	transport system, permease component
WJ02_RS07810	COG0583	DNA-binding transcription factor activity
WJ02_RS07815	COG0560	Phosphoserine phosphatase
WJ02_RS07820	COG0626	cystathionine gamma-synthase activity
WJ02_RS07835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WJ02_RS07855	COG1028	Short-chain dehydrogenase reductase Sdr
WJ02_RS07860	COG0183	Belongs to the thiolase family
WJ02_RS07865	COG3243	poly(R)-hydroxyalkanoic acid synthase
WJ02_RS07875	COG0564	pseudouridine synthase activity
WJ02_RS07885	COG1199	ATP-dependent helicase activity
WJ02_RS07900	COG2183	response to ionizing radiation
WJ02_RS07905	COG3158	transport of potassium into the cell
WJ02_RS07910	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
WJ02_RS07920	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
WJ02_RS07930	COG0330	HflC and HflK could
WJ02_RS07935	COG0330	HflC and HflK could
WJ02_RS07940	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WJ02_RS07950	COG1160	GTP binding
WJ02_RS07955	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WJ02_RS07965	COG0124	histidyl-tRNA synthetase
WJ02_RS07970	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
WJ02_RS07980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WJ02_RS07990	COG0670	Belongs to the BI1 family
WJ02_RS07995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WJ02_RS08020	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WJ02_RS08025	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
WJ02_RS08030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WJ02_RS08035	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WJ02_RS08040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WJ02_RS08045	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WJ02_RS08060	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WJ02_RS08065	COG0789	Transcriptional regulator
WJ02_RS08070	COG0477	Major facilitator Superfamily
WJ02_RS08075	COG3228	Belongs to the MtfA family
WJ02_RS08080	COG0254	rRNA binding
WJ02_RS08090	COG0534	Mate efflux family protein
WJ02_RS08095	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WJ02_RS08105	COG0022	dehydrogenase e1 component
WJ02_RS08110	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WJ02_RS08115	COG1028	Short-chain dehydrogenase reductase Sdr
WJ02_RS08120	COG3199	ATP-NAD kinase
WJ02_RS08125	COG3284	Transcriptional regulator
WJ02_RS08150	COG0542	response to heat
WJ02_RS08155	COG1959	2 iron, 2 sulfur cluster binding
WJ02_RS08160	COG2346	COG2346, Truncated hemoglobins
WJ02_RS08165	COG0314	molybdopterin synthase activity
WJ02_RS08170	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WJ02_RS08190	COG0436	Aminotransferase
WJ02_RS08200	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WJ02_RS08210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WJ02_RS08225	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WJ02_RS08225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WJ02_RS08230	COG0726	polysaccharide deacetylase
WJ02_RS08235	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WJ02_RS08240	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WJ02_RS08245	COG0791	NLP P60 protein
WJ02_RS08250	COG0306	phosphate transporter
WJ02_RS08260	COG0305	Participates in initiation and elongation during chromosome replication
WJ02_RS08265	COG0359	binds to the 23S rRNA
WJ02_RS08270	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WJ02_RS08275	COG2965	DNA replication, synthesis of RNA primer
WJ02_RS08280	COG0360	Binds together with S18 to 16S ribosomal RNA
WJ02_RS08285	COG0583	DNA-binding transcription factor activity
WJ02_RS08290	COG3960	tartronate-semialdehyde synthase activity
WJ02_RS08295	COG3622	Belongs to the hyi family
WJ02_RS08300	COG2084	Dehydrogenase
WJ02_RS08305	COG1652	LysM domain
WJ02_RS08310	COG0252	asparaginase activity
WJ02_RS08330	COG0438	transferase activity, transferring glycosyl groups
WJ02_RS08355	COG0084	hydrolase, TatD family'
WJ02_RS08365	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WJ02_RS08370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WJ02_RS08385	COG2153	protein acetylation
WJ02_RS08420	COG2814	Major facilitator Superfamily
WJ02_RS08445	COG2199	diguanylate cyclase activity
WJ02_RS08450	COG0183	Belongs to the thiolase family
WJ02_RS08455	COG1335	isochorismatase
WJ02_RS08465	COG0318	PFAM AMP-dependent synthetase and ligase
WJ02_RS08470	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WJ02_RS08475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WJ02_RS08480	COG2917	probably involved in intracellular septation
WJ02_RS08490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WJ02_RS08500	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WJ02_RS08500	COG0047	phosphoribosylformylglycinamidine synthase activity
WJ02_RS08510	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WJ02_RS08510	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WJ02_RS08520	COG4181	ATPase activity
WJ02_RS08545	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WJ02_RS08550	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WJ02_RS08555	COG0740	serine-type endopeptidase activity
WJ02_RS08560	COG0544	peptidyl-prolyl cis-trans isomerase activity
WJ02_RS08565	COG1929	Belongs to the glycerate kinase type-1 family
WJ02_RS08575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WJ02_RS08635	COG0582	viral genome integration into host DNA
WJ02_RS08775	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WJ02_RS08780	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
WJ02_RS08785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WJ02_RS08790	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WJ02_RS08820	COG1970	mechanosensitive ion channel activity
WJ02_RS08835	COG3360	Dodecin
WJ02_RS08850	COG2351	hydroxyisourate hydrolase activity
WJ02_RS08870	COG4266	Belongs to the allantoicase family
WJ02_RS08875	COG3195	allantoin biosynthetic process
WJ02_RS08875	COG3648	Uricase
WJ02_RS08890	COG1953	Uracil, thiamine, allantoin
WJ02_RS08895	COG1802	Transcriptional regulator
WJ02_RS08900	COG1619	proteins homologs of microcin C7 resistance protein MccF
WJ02_RS08905	COG0590	tRNA wobble adenosine to inosine editing
WJ02_RS08960	COG0519	Catalyzes the synthesis of GMP from XMP
WJ02_RS08960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WJ02_RS09000	COG0697	spore germination
WJ02_RS09025	COG0330	HflC and HflK could
WJ02_RS09040	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WJ02_RS09045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WJ02_RS09050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WJ02_RS09055	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WJ02_RS09060	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WJ02_RS09070	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WJ02_RS09075	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
WJ02_RS09085	COG0750	zinc metalloprotease
WJ02_RS09090	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WJ02_RS09100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WJ02_RS09105	COG0233	cytoplasmic translational termination
WJ02_RS09110	COG0528	UMP kinase activity
WJ02_RS09115	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WJ02_RS09120	COG0052	Belongs to the universal ribosomal protein uS2 family
WJ02_RS09125	COG0024	Methionine aminopeptidase
WJ02_RS09130	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
WJ02_RS09135	COG1187	pseudouridine synthase activity
WJ02_RS09140	COG0242	peptide deformylase activity
WJ02_RS09145	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WJ02_RS09175	COG1393	Belongs to the ArsC family
WJ02_RS09180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WJ02_RS09185	COG2890	protein-(glutamine-N5) methyltransferase activity
WJ02_RS09195	COG0386	Belongs to the glutathione peroxidase family
WJ02_RS09200	COG0488	(ABC) transporter
WJ02_RS09220	COG0477	Major facilitator Superfamily
WJ02_RS09235	COG1573	uracil-dna glycosylase
WJ02_RS09255	COG0513	Belongs to the DEAD box helicase family
WJ02_RS09260	COG2224	Isocitrate lyase
WJ02_RS09270	COG0583	DNA-binding transcription factor activity
WJ02_RS09280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WJ02_RS09335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WJ02_RS09340	COG1752	Esterase of the alpha-beta hydrolase superfamily
WJ02_RS09345	COG0791	NLP P60 protein
WJ02_RS09350	COG4172	Belongs to the ABC transporter superfamily
WJ02_RS09355	COG4239	(ABC) transporter, permease
WJ02_RS09360	COG4174	ABC transporter (Permease)
WJ02_RS09375	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WJ02_RS09410	COG0527	aspartate kinase activity
WJ02_RS09415	COG0037	tRNA processing
WJ02_RS09420	COG0825	malonyl-CoA metabolic process
WJ02_RS09430	COG0215	cysteine-tRNA ligase activity
WJ02_RS09440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WJ02_RS09450	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WJ02_RS09455	COG1045	serine acetyltransferase
WJ02_RS09465	COG0483	inositol monophosphate 1-phosphatase activity
WJ02_RS09470	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
WJ02_RS09495	COG0625	glutathione transferase activity
WJ02_RS09505	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WJ02_RS09520	COG2850	peptidyl-arginine hydroxylation
WJ02_RS09525	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
WJ02_RS09530	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WJ02_RS09535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WJ02_RS09545	COG0180	Tryptophanyl-tRNA synthetase
WJ02_RS09550	COG1994	Peptidase M50
WJ02_RS09555	COG0009	L-threonylcarbamoyladenylate synthase
WJ02_RS09560	COG0613	PHP domain protein
WJ02_RS09565	COG0596	Alpha beta hydrolase
WJ02_RS09570	COG2833	Protein of unknown function (DUF455)
WJ02_RS09580	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WJ02_RS09590	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WJ02_RS09595	COG0148	phosphopyruvate hydratase activity
WJ02_RS09600	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WJ02_RS09605	COG0504	CTP synthase activity
WJ02_RS09615	COG2333	competence protein COMEC
WJ02_RS09615	COG0658	competence protein
WJ02_RS09620	COG0084	hydrolase, TatD family'
WJ02_RS09640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WJ02_RS09645	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WJ02_RS09665	COG0443	Heat shock 70 kDa protein
WJ02_RS09670	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WJ02_RS09675	COG0316	Belongs to the HesB IscA family
WJ02_RS09680	COG0822	iron-sulfur transferase activity
WJ02_RS09685	COG1104	cysteine desulfurase activity
WJ02_RS09695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WJ02_RS09715	COG1414	Transcriptional regulator
WJ02_RS09730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WJ02_RS09735	COG0508	dehydrogenase complex catalyzes the overall conversion of
WJ02_RS09740	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WJ02_RS09750	COG4566	intracellular signal transduction
WJ02_RS09755	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WJ02_RS09760	COG0339	signal peptide processing
WJ02_RS09765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WJ02_RS09770	COG1794	racemase activity, acting on amino acids and derivatives
WJ02_RS09785	COG1505	serine-type exopeptidase activity
WJ02_RS09800	COG0174	glutamine synthetase
WJ02_RS09810	COG1546	Belongs to the CinA family
WJ02_RS09810	COG1058	Belongs to the CinA family
WJ02_RS09830	COG1643	Atp-dependent helicase
WJ02_RS09835	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WJ02_RS09835	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WJ02_RS09855	COG0174	glutamine synthetase
WJ02_RS09860	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WJ02_RS09885	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
WJ02_RS09895	COG2986	histidine ammonia-lyase
WJ02_RS09915	COG0583	DNA-binding transcription factor activity
WJ02_RS09960	COG2310	stress, protein
WJ02_RS09970	COG2304	oxidoreductase activity
WJ02_RS10005	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WJ02_RS10040	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WJ02_RS10090	COG0672	)-iron permease
WJ02_RS10095	COG4633	Protein conserved in bacteria
WJ02_RS10105	COG0556	nucleotide-excision repair
WJ02_RS10115	COG1028	Short-chain dehydrogenase reductase Sdr
WJ02_RS10120	COG0667	Aldo Keto reductase
WJ02_RS10125	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WJ02_RS10190	COG2866	Carboxypeptidase
WJ02_RS10195	COG3022	response to hydroperoxide
WJ02_RS10205	COG0436	Aminotransferase
WJ02_RS10210	COG0625	glutathione transferase activity
WJ02_RS10215	COG1024	Enoyl-CoA hydratase
WJ02_RS10220	COG0625	glutathione transferase activity
WJ02_RS10235	COG1960	acyl-CoA dehydrogenase activity
WJ02_RS10240	COG1960	acyl-CoA dehydrogenase activity
WJ02_RS10260	COG1007	ATP synthesis coupled electron transport
WJ02_RS10275	COG0713	ATP synthesis coupled electron transport
WJ02_RS10285	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WJ02_RS10290	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WJ02_RS10295	COG1034	ATP synthesis coupled electron transport
WJ02_RS10295	COG1034	ATP synthesis coupled electron transport
WJ02_RS10305	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WJ02_RS10310	COG0649	NAD binding
WJ02_RS10315	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WJ02_RS10325	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WJ02_RS10340	COG0149	triose-phosphate isomerase activity
WJ02_RS10350	COG1185	polyribonucleotide nucleotidyltransferase activity
WJ02_RS10360	COG0683	leucine binding
WJ02_RS10370	COG0288	reversible hydration of carbon dioxide
WJ02_RS10375	COG0659	secondary active sulfate transmembrane transporter activity
WJ02_RS10380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WJ02_RS10385	COG1183	phosphatidylcholine synthase activity
WJ02_RS10390	COG0688	phosphatidylethanolamine metabolic process
WJ02_RS10405	COG0028	Belongs to the TPP enzyme family
WJ02_RS10435	COG0438	transferase activity, transferring glycosyl groups
WJ02_RS10455	COG1028	Short-chain dehydrogenase reductase Sdr
WJ02_RS10460	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WJ02_RS10470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WJ02_RS10480	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
WJ02_RS10490	COG2076	Multidrug Resistance protein
WJ02_RS10500	COG0745	RESPONSE REGULATOR receiver
WJ02_RS10505	COG2205	protein histidine kinase activity
WJ02_RS10510	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
WJ02_RS10515	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
WJ02_RS10520	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
WJ02_RS10540	COG1028	Short-chain dehydrogenase reductase Sdr
WJ02_RS10545	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WJ02_RS10550	COG0217	transcriptional regulatory protein
WJ02_RS10555	COG0151	Belongs to the GarS family
WJ02_RS10570	COG0799	negative regulation of ribosome biogenesis
WJ02_RS10575	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WJ02_RS10605	COG3171	Protein conserved in bacteria
WJ02_RS10640	COG1216	Glycosyl transferase, family 2
WJ02_RS10650	COG0859	PFAM glycosyl transferase family 9
WJ02_RS10670	COG1054	Belongs to the UPF0176 family
WJ02_RS10680	COG0513	Belongs to the DEAD box helicase family
WJ02_RS10685	COG3895	Periplasmic Protein
WJ02_RS10695	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
WJ02_RS10705	COG1674	ftsk spoiiie
WJ02_RS10710	COG2706	6-phosphogluconolactonase activity
WJ02_RS10715	COG3387	PFAM Glycoside hydrolase 15-related
WJ02_RS10725	COG1309	transcriptional regulator
WJ02_RS10730	COG2878	Part of a membrane complex involved in electron transport
WJ02_RS10735	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WJ02_RS10760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WJ02_RS10770	COG3135	benzoate transporter
WJ02_RS10775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WJ02_RS10835	COG0697	spore germination
WJ02_RS10840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WJ02_RS10850	COG0384	phenazine biosynthesis protein PhzF
WJ02_RS10870	COG0583	DNA-binding transcription factor activity
WJ02_RS10890	COG0488	(ABC) transporter
WJ02_RS10910	COG0582	viral genome integration into host DNA
WJ02_RS10915	COG4574	serine-type endopeptidase inhibitor activity
WJ02_RS10935	COG2814	Major facilitator Superfamily
WJ02_RS10965	COG1116	anion transmembrane transporter activity
WJ02_RS10970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WJ02_RS11045	COG2827	Endonuclease containing a URI domain
WJ02_RS11050	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WJ02_RS11065	COG2271	Major facilitator Superfamily
WJ02_RS11080	COG0181	hydroxymethylbilane synthase activity
WJ02_RS11085	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WJ02_RS11090	COG2226	methyltransferase
WJ02_RS11100	COG0165	Argininosuccinate lyase
WJ02_RS11105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WJ02_RS11130	COG0489	protein tyrosine kinase activity
WJ02_RS11135	COG3047	cAMP biosynthetic process
WJ02_RS11135	COG2885	chlorophyll binding
WJ02_RS11140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WJ02_RS11140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WJ02_RS11160	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
WJ02_RS11165	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WJ02_RS11170	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
WJ02_RS11180	COG2259	Doxx family
WJ02_RS11185	COG1492	cobalamin metabolic process
WJ02_RS11195	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
WJ02_RS11205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WJ02_RS11215	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
WJ02_RS11220	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
WJ02_RS11225	COG1120	ATPase activity
WJ02_RS11230	COG4139	cobalamin transport
WJ02_RS11265	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WJ02_RS11285	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WJ02_RS11305	COG1648	precorrin-2 dehydrogenase activity
WJ02_RS11305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WJ02_RS11310	COG2895	sulfate adenylyltransferase (ATP) activity
WJ02_RS11320	COG0175	sulfate reduction
WJ02_RS11335	COG0583	DNA-binding transcription factor activity
WJ02_RS11400	COG1028	Short-chain dehydrogenase reductase Sdr
WJ02_RS11415	COG1187	pseudouridine synthase activity
WJ02_RS11430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WJ02_RS11430	COG0543	2 iron, 2 sulfur cluster binding
WJ02_RS11435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WJ02_RS11440	COG0456	acetyltransferase
WJ02_RS11475	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WJ02_RS11480	COG1047	Peptidyl-prolyl cis-trans
WJ02_RS11485	COG2003	Belongs to the UPF0758 family
WJ02_RS11500	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WJ02_RS11510	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
WJ02_RS11520	COG3264	Mechanosensitive ion channel
WJ02_RS11520	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
WJ02_RS11525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WJ02_RS11525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WJ02_RS11530	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WJ02_RS11535	COG0196	riboflavin kinase activity
WJ02_RS11540	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WJ02_RS11545	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WJ02_RS11550	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WJ02_RS11555	COG0756	dUTP diphosphatase activity
WJ02_RS11565	COG1113	amino acid transport
WJ02_RS11570	COG0542	response to heat
WJ02_RS11580	COG1278	Cold shock
WJ02_RS11620	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
WJ02_RS11625	COG0656	L-ascorbic acid biosynthetic process
WJ02_RS11630	COG2188	Transcriptional regulator
WJ02_RS11635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WJ02_RS11650	COG2814	Major facilitator Superfamily
WJ02_RS11680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WJ02_RS11685	COG1570	exodeoxyribonuclease VII activity
WJ02_RS11690	COG1663	tetraacyldisaccharide 4'-kinase activity
WJ02_RS11695	COG2835	tetraacyldisaccharide 4'-kinase activity
WJ02_RS11700	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WJ02_RS11705	COG0563	adenylate kinase activity
WJ02_RS11715	COG0728	peptidoglycan biosynthetic process
WJ02_RS11735	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WJ02_RS11740	COG1666	GTP binding
WJ02_RS11745	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WJ02_RS11750	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WJ02_RS11755	COG0318	PFAM AMP-dependent synthetase and ligase
WJ02_RS11760	COG4974	Belongs to the 'phage' integrase family
WJ02_RS11770	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WJ02_RS11775	COG0802	atpase or kinase
WJ02_RS11780	COG0860	N-Acetylmuramoyl-L-alanine amidase
WJ02_RS11790	COG1741	Belongs to the pirin family
WJ02_RS11800	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WJ02_RS11805	COG0259	pyridoxamine-phosphate oxidase activity
WJ02_RS11810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WJ02_RS11820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WJ02_RS11825	COG3391	amine dehydrogenase activity
WJ02_RS11835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WJ02_RS11840	COG1522	sequence-specific DNA binding
WJ02_RS11845	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
WJ02_RS11855	COG3483	tryptophan 2,3-dioxygenase activity
WJ02_RS11860	COG0246	Mannitol dehydrogenase
WJ02_RS11865	COG1070	Carbohydrate kinase
WJ02_RS11875	COG3842	ATPase activity
WJ02_RS11880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WJ02_RS11890	COG4209	transmembrane transport
WJ02_RS11900	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
WJ02_RS11905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WJ02_RS11915	COG0735	belongs to the Fur family
WJ02_RS11925	COG1121	(ABC) transporter
WJ02_RS11930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WJ02_RS11935	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
WJ02_RS11940	COG1070	Carbohydrate kinase
WJ02_RS11945	COG2233	PERMEase
WJ02_RS11955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WJ02_RS11975	COG4977	sequence-specific DNA binding
WJ02_RS11980	COG0489	protein tyrosine kinase activity
WJ02_RS11980	COG3206	protein involved in exopolysaccharide biosynthesis
WJ02_RS12000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WJ02_RS12015	COG2027	D-alanyl-D-alanine carboxypeptidase
WJ02_RS12030	COG0009	L-threonylcarbamoyladenylate synthase
WJ02_RS12035	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WJ02_RS12040	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WJ02_RS12045	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WJ02_RS12055	COG0469	pyruvate kinase activity
WJ02_RS12060	COG0126	phosphoglycerate kinase activity
WJ02_RS12095	COG0429	hydrolase of the alpha beta-hydrolase fold
WJ02_RS12105	COG4783	chaperone-mediated protein folding
WJ02_RS12110	COG0315	cyclic pyranopterin monophosphate synthase activity
WJ02_RS12140	COG4969	Belongs to the N-Me-Phe pilin family
WJ02_RS12145	COG0861	Integral membrane protein TerC family
WJ02_RS12150	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WJ02_RS12155	COG0045	succinate-CoA ligase (ADP-forming) activity
WJ02_RS12165	COG2137	regulation of response to DNA damage stimulus
WJ02_RS12170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WJ02_RS12235	COG3328	transposase activity
WJ02_RS12245	COG3846	protein secretion by the type IV secretion system
WJ02_RS12260	COG0583	DNA-binding transcription factor activity
WJ02_RS12265	COG4977	sequence-specific DNA binding
WJ02_RS12295	COG2186	Transcriptional regulator
WJ02_RS12300	COG4948	Mandelate Racemase Muconate Lactonizing
WJ02_RS12310	COG2863	cytochrome
WJ02_RS12320	COG0513	Belongs to the DEAD box helicase family
WJ02_RS12360	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WJ02_RS12365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WJ02_RS12370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WJ02_RS12375	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WJ02_RS12380	COG1396	sequence-specific DNA binding
WJ02_RS12385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WJ02_RS12390	COG1702	phosphate starvation-inducible protein PhoH
WJ02_RS12400	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
WJ02_RS12410	COG0815	Transfers the fatty acyl group on membrane lipoproteins
WJ02_RS12420	COG0752	glycyl-tRNA synthetase alpha subunit
WJ02_RS12425	COG0751	glycine-tRNA ligase activity
WJ02_RS12430	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WJ02_RS12435	COG0204	Acyl-transferase
WJ02_RS12460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WJ02_RS12465	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WJ02_RS12475	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WJ02_RS12490	COG5265	(ABC) transporter
WJ02_RS12505	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WJ02_RS12515	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WJ02_RS12535	COG1024	Enoyl-CoA hydratase
WJ02_RS12540	COG0183	Belongs to the thiolase family
WJ02_RS12545	COG1024	Enoyl-CoA hydratase
WJ02_RS12545	COG1250	3-hydroxyacyl-CoA dehydrogenase
WJ02_RS12550	COG1960	acyl-CoA dehydrogenase activity
WJ02_RS12565	COG0494	nUDIX hydrolase
WJ02_RS12570	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WJ02_RS12585	COG0500	methyltransferase
WJ02_RS12605	COG2226	methyltransferase
WJ02_RS12625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WJ02_RS12630	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WJ02_RS12630	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WJ02_RS12635	COG0251	oxidation-reduction process
WJ02_RS12640	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
WJ02_RS12645	COG1737	Transcriptional regulator
WJ02_RS12645	COG0837	glucose binding
WJ02_RS12665	COG0477	Major facilitator Superfamily
WJ02_RS12680	COG0235	Class ii aldolase
WJ02_RS12685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WJ02_RS12690	COG2186	Transcriptional regulator
WJ02_RS12695	COG0247	lactate metabolic process
WJ02_RS12705	COG1139	Iron-sulfur cluster binding protein
WJ02_RS12710	COG1620	l-lactate permease
WJ02_RS12715	COG0501	Belongs to the peptidase M48B family
WJ02_RS12730	COG1028	Short-chain dehydrogenase reductase Sdr
WJ02_RS12745	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WJ02_RS12770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WJ02_RS12795	COG1028	Short-chain dehydrogenase reductase Sdr
WJ02_RS12800	COG0183	Belongs to the thiolase family
WJ02_RS12815	COG0629	single-stranded DNA binding
WJ02_RS12820	COG2814	Major facilitator Superfamily
WJ02_RS12845	COG1280	lysine exporter protein (LysE YggA)
WJ02_RS12850	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WJ02_RS12865	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WJ02_RS12880	COG1137	ATPase activity
WJ02_RS12885	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WJ02_RS12890	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WJ02_RS12905	COG1660	Displays ATPase and GTPase activities
WJ02_RS12915	COG1194	a g-specific adenine glycosylase
WJ02_RS12920	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WJ02_RS12930	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
WJ02_RS12935	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WJ02_RS12945	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WJ02_RS12950	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
WJ02_RS12965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WJ02_RS12970	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WJ02_RS12975	COG0742	ribosomal rna small subunit methyltransferase
WJ02_RS12985	COG0625	glutathione transferase activity
WJ02_RS12990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WJ02_RS12995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WJ02_RS13010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WJ02_RS13025	COG1294	oxidase, subunit
WJ02_RS13040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WJ02_RS13040	COG1263	PTS System
WJ02_RS13040	COG2190	(PTS) system
WJ02_RS13045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WJ02_RS13045	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WJ02_RS13050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WJ02_RS13055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WJ02_RS13060	COG2188	Transcriptional regulator
WJ02_RS13065	COG0587	DNA-directed DNA polymerase activity
WJ02_RS13085	COG0840	transmembrane signaling receptor activity
WJ02_RS13095	COG1999	signal sequence binding
WJ02_RS13100	COG0109	protoheme IX farnesyltransferase activity
WJ02_RS13140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WJ02_RS13155	COG2226	methyltransferase
WJ02_RS13160	COG1040	competence protein
WJ02_RS13165	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
WJ02_RS13170	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
WJ02_RS13175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WJ02_RS13180	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WJ02_RS13190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WJ02_RS13195	COG0588	phosphoglycerate mutase activity
WJ02_RS13200	COG0793	Belongs to the peptidase S41A family
WJ02_RS13205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WJ02_RS13210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WJ02_RS13215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WJ02_RS13225	COG0189	ligase activity
WJ02_RS13235	COG0004	ammonium transporteR
WJ02_RS13245	COG2960	long-chain fatty acid transporting porin activity
WJ02_RS13270	COG0606	chelatase, subunit chli
WJ02_RS13290	COG4191	Histidine kinase
WJ02_RS13295	COG1301	dicarboxylic acid transport
WJ02_RS13300	COG1960	acyl-CoA dehydrogenase activity
WJ02_RS13305	COG1960	acyl-CoA dehydrogenase activity
WJ02_RS13310	COG1250	3-hydroxyacyl-CoA dehydrogenase
WJ02_RS13310	COG1024	Enoyl-CoA hydratase
WJ02_RS13315	COG0583	DNA-binding transcription factor activity
WJ02_RS13320	COG0405	Gamma-glutamyltransferase
WJ02_RS13325	COG3012	SEC-C Motif Domain Protein
WJ02_RS13325	COG3318	Belongs to the UPF0149 family
WJ02_RS13330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WJ02_RS13340	COG4521	taurine ABC transporter
WJ02_RS13350	COG0321	lipoyl(octanoyl) transferase activity
WJ02_RS13360	COG0583	DNA-binding transcription factor activity
WJ02_RS13365	COG2921	Belongs to the UPF0250 family
WJ02_RS13375	COG1686	Belongs to the peptidase S11 family
WJ02_RS13405	COG1127	ABC transporter
WJ02_RS13410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WJ02_RS13415	COG0737	Belongs to the 5'-nucleotidase family
WJ02_RS13425	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
WJ02_RS13425	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
WJ02_RS13430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
WJ02_RS13440	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WJ02_RS13460	COG1024	Enoyl-CoA hydratase
WJ02_RS13465	COG0179	Fumarylacetoacetate (FAA) hydrolase
WJ02_RS13500	COG0018	arginyl-trna synthetase
WJ02_RS13510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WJ02_RS13515	COG0300	oxidoreductase activity
WJ02_RS13520	COG0747	negative chemotaxis
WJ02_RS13535	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
WJ02_RS13540	COG0288	reversible hydration of carbon dioxide
WJ02_RS13545	COG0300	oxidoreductase activity
WJ02_RS13550	COG3012	SEC-C Motif Domain Protein
WJ02_RS13565	COG0156	8-amino-7-oxononanoate synthase activity
WJ02_RS13570	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WJ02_RS13575	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WJ02_RS13585	COG2200	EAL domain
WJ02_RS13585	COG2199	diguanylate cyclase activity
WJ02_RS13590	COG0025	NhaP-type Na H and K H
WJ02_RS13600	COG0110	maltose O-acetyltransferase activity
WJ02_RS13610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WJ02_RS13620	COG0583	DNA-binding transcription factor activity
WJ02_RS13630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WJ02_RS13635	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WJ02_RS13640	COG2080	2 iron, 2 sulfur cluster binding
WJ02_RS13650	COG3511	phospholipase C
WJ02_RS13665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WJ02_RS13695	COG0596	Alpha beta hydrolase
WJ02_RS13705	COG0583	DNA-binding transcription factor activity
WJ02_RS13730	COG1609	Transcriptional regulator
WJ02_RS13770	COG0037	tRNA processing
WJ02_RS13775	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WJ02_RS13780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WJ02_RS13810	COG1012	belongs to the aldehyde dehydrogenase family
WJ02_RS13815	COG1917	Cupin 2, conserved barrel domain protein
WJ02_RS13820	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WJ02_RS13825	COG0174	glutamine synthetase
WJ02_RS13840	COG3842	ATPase activity
WJ02_RS13845	COG1176	ABC-type spermidine putrescine transport system, permease component I
WJ02_RS13850	COG1177	transmembrane transport
WJ02_RS13860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WJ02_RS13865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WJ02_RS13895	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WJ02_RS13920	COG2233	PERMEase
WJ02_RS13935	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
WJ02_RS13945	COG1706	bacterial-type flagellum-dependent cell motility
WJ02_RS13950	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WJ02_RS13970	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
WJ02_RS13975	COG1558	bacterial-type flagellum-dependent cell motility
WJ02_RS13980	COG1815	bacterial-type flagellum-dependent cell motility
WJ02_RS14000	COG0006	proline dipeptidase activity
WJ02_RS14010	COG0617	tRNA 3'-terminal CCA addition
WJ02_RS14025	COG0741	lytic transglycosylase activity
WJ02_RS14030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WJ02_RS14040	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WJ02_RS14045	COG1984	allophanate hydrolase subunit 2
WJ02_RS14050	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
WJ02_RS14060	COG4608	Belongs to the ABC transporter superfamily
WJ02_RS14065	COG0444	Belongs to the ABC transporter superfamily
WJ02_RS14070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WJ02_RS14075	COG0601	transmembrane transport
WJ02_RS14080	COG0747	negative chemotaxis
WJ02_RS14095	COG0579	oxidoreductase
WJ02_RS14100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WJ02_RS14115	COG3568	Endonuclease Exonuclease Phosphatase
WJ02_RS14130	COG2197	response regulator
WJ02_RS14135	COG0531	amino acid
WJ02_RS14150	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WJ02_RS14165	COG1516	flagellar protein fliS
WJ02_RS14170	COG1677	Flagellar hook-basal body complex protein FliE
WJ02_RS14240	COG0667	Aldo Keto reductase
WJ02_RS14260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
WJ02_RS14265	COG1560	Kdo2-lipid A biosynthetic process
WJ02_RS14270	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WJ02_RS14280	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WJ02_RS14285	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WJ02_RS14290	COG0523	cobalamin synthesis protein
WJ02_RS14300	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WJ02_RS14305	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WJ02_RS14310	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
WJ02_RS14325	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WJ02_RS14335	COG1309	transcriptional regulator
WJ02_RS14345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WJ02_RS14350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WJ02_RS14355	COG2814	Major facilitator Superfamily
WJ02_RS14365	COG2207	Transcriptional regulator
WJ02_RS14370	COG1064	alcohol dehydrogenase
WJ02_RS14375	COG0708	Exodeoxyribonuclease III
WJ02_RS14380	COG2326	polyphosphate kinase activity
WJ02_RS14385	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WJ02_RS14390	COG0154	amidase activity
WJ02_RS14395	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WJ02_RS14400	COG1077	Cell shape determining protein MreB Mrl
WJ02_RS14415	COG0768	penicillin binding
WJ02_RS14420	COG0772	Belongs to the SEDS family
WJ02_RS14435	COG0720	synthase
WJ02_RS14440	COG0602	queuosine metabolic process
WJ02_RS14445	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WJ02_RS14455	COG2204	response regulator
WJ02_RS14460	COG5000	phosphorelay sensor kinase activity
WJ02_RS14475	COG0501	Belongs to the peptidase M48B family
WJ02_RS14485	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WJ02_RS14490	COG0242	peptide deformylase activity
WJ02_RS14495	COG0758	DNA mediated transformation
WJ02_RS14510	COG0583	DNA-binding transcription factor activity
WJ02_RS14515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WJ02_RS14595	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WJ02_RS14615	COG1475	DNA binding
WJ02_RS14655	COG1620	l-lactate permease
WJ02_RS14680	COG2169	Transcriptional regulator
WJ02_RS14680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WJ02_RS14700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WJ02_RS14710	COG5001	Diguanylate cyclase
WJ02_RS14710	COG2203	Gaf domain
WJ02_RS14710	COG3706	GGDEF domain
WJ02_RS14710	COG4251	negative regulation of phosphorylation
WJ02_RS14715	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WJ02_RS14725	COG0706	membrane insertase activity
WJ02_RS14730	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
WJ02_RS15190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WJ02_RS15795	COG0280	phosphate acetyltransferase
WJ02_RS15795	COG0281	malic enzyme
WJ02_RS15945	COG0085	RNA polymerase activity
WJ02_RS15970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WJ02_RS16135	COG0584	glycerophosphoryl diester phosphodiesterase
WJ02_RS16265	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WJ02_RS16515	COG0488	(ABC) transporter
WJ02_RS16765	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WJ02_RS16895	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WJ02_RS16895	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WJ02_RS17000	COG3734	2-keto-3-deoxy-galactonokinase
WJ02_RS17585	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WJ02_RS17610	COG1420	regulation of RNA biosynthetic process
WJ02_RS17825	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WJ02_RS17835	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WJ02_RS18200	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WJ02_RS18490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WJ02_RS18605	COG0402	S-adenosylhomocysteine deaminase activity
WJ02_RS18775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WJ02_RS18935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WJ02_RS19005	COG0416	fatty acid biosynthetic process
WJ02_RS19070	COG0322	excinuclease ABC activity
WJ02_RS19620	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WJ02_RS19770	COG0477	Major facilitator Superfamily
WJ02_RS19820	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WJ02_RS19845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WJ02_RS19860	COG0581	inorganic phosphate transmembrane transporter activity
WJ02_RS19880	COG0248	Ppx GppA phosphatase
WJ02_RS20240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WJ02_RS20370	COG0525	valine-tRNA ligase activity
WJ02_RS20390	COG0210	DNA helicase
WJ02_RS20490	COG2271	Major facilitator Superfamily
WJ02_RS20625	COG2251	uridine kinase activity
WJ02_RS20625	COG0195	Participates in both transcription termination and antitermination
WJ02_RS20645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WJ02_RS20820	COG0318	PFAM AMP-dependent synthetase and ligase
WJ02_RS20910	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WJ02_RS21050	COG2766	serine protein kinase
WJ02_RS21065	COG2719	SpoVR family
WJ02_RS21230	COG4774	siderophore transport
WJ02_RS21810	COG3243	poly(R)-hydroxyalkanoic acid synthase
WJ02_RS21845	COG1160	GTP binding
WJ02_RS21970	COG0534	Mate efflux family protein
WJ02_RS22000	COG0022	dehydrogenase e1 component
WJ02_RS22360	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WJ02_RS22360	COG0047	phosphoribosylformylglycinamidine synthase activity
WJ02_RS22865	COG0519	Catalyzes the synthesis of GMP from XMP
WJ02_RS22865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WJ02_RS23140	COG2224	Isocitrate lyase
WJ02_RS23375	COG2267	carboxylic ester hydrolase activity
WJ02_RS23660	COG0174	glutamine synthetase
WJ02_RS24150	COG0688	phosphatidylethanolamine metabolic process
WJ02_RS24335	COG0463	Glycosyl transferase, family 2
WJ02_RS24440	COG1674	ftsk spoiiie
WJ02_RS24690	COG1116	anion transmembrane transporter activity
WJ02_RS25085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WJ02_RS25085	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
WJ02_RS25310	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WJ02_RS25395	COG0668	transmembrane transport
WJ02_RS25405	COG4302	ethanolamine ammonia-lyase activity
WJ02_RS25570	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WJ02_RS26240	COG0584	glycerophosphoryl diester phosphodiesterase
WJ02_RS26270	COG0069	glutamate synthase activity
WJ02_RS26270	COG0070	glutamate synthase
WJ02_RS26270	COG0067	glutamate synthase
WJ02_RS26280	COG0070	glutamate synthase
WJ02_RS26280	COG0069	glutamate synthase activity
WJ02_RS26280	COG0067	glutamate synthase
WJ02_RS26305	COG4178	(ABC) transporter
WJ02_RS26425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WJ02_RS26825	COG0488	(ABC) transporter
WJ02_RS27745	COG0277	FAD linked oxidase domain protein
WJ02_RS27910	COG0823	Involved in the tonB-independent uptake of proteins
WJ02_RS28390	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
WJ02_RS28595	COG3842	ATPase activity
WJ02_RS28910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WJ02_RS29395	COG3511	phospholipase C