locus-tag	class	description
WL96_RS00010	COG0592	DNA-directed DNA polymerase activity
WL96_RS00070	COG3038	cytochrome b561
WL96_RS00075	COG0753	catalase activity
WL96_RS00110	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WL96_RS00115	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
WL96_RS00145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WL96_RS00160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WL96_RS00180	COG1987	bacterial-type flagellum assembly
WL96_RS00210	COG1346	cytolysis
WL96_RS00215	COG1380	Effector of murein hydrolase LrgA
WL96_RS00220	COG0583	DNA-binding transcription factor activity
WL96_RS00225	COG2814	Major facilitator Superfamily
WL96_RS00275	COG2165	general secretion pathway protein
WL96_RS00290	COG1459	type II secretion system
WL96_RS00305	COG0741	lytic transglycosylase activity
WL96_RS00310	COG0523	cobalamin synthesis protein
WL96_RS00320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WL96_RS00320	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
WL96_RS00330	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
WL96_RS00340	COG0519	Catalyzes the synthesis of GMP from XMP
WL96_RS00340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WL96_RS00345	COG1902	pentaerythritol trinitrate reductase activity
WL96_RS00355	COG0642	Histidine kinase
WL96_RS00370	COG2154	pterin-4-alpha-carbinolamine dehydratase
WL96_RS00375	COG3186	Phenylalanine-4-hydroxylase
WL96_RS00380	COG1522	sequence-specific DNA binding
WL96_RS00390	COG0583	DNA-binding transcription factor activity
WL96_RS00445	COG0445	tRNA wobble uridine modification
WL96_RS00450	COG0357	Ribosomal RNA small subunit methyltransferase G
WL96_RS00455	COG1192	Involved in chromosome partitioning
WL96_RS00460	COG1475	DNA binding
WL96_RS00465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WL96_RS00475	COG0356	it plays a direct role in the translocation of protons across the membrane
WL96_RS00490	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WL96_RS00495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WL96_RS00500	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WL96_RS00505	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WL96_RS00510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WL96_RS00515	COG0318	PFAM AMP-dependent synthetase and ligase
WL96_RS00525	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WL96_RS00530	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WL96_RS00535	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WL96_RS00535	COG0506	proline dehydrogenase activity
WL96_RS00535	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WL96_RS00540	COG0683	leucine binding
WL96_RS00545	COG1960	acyl-CoA dehydrogenase activity
WL96_RS00555	COG0436	Aminotransferase
WL96_RS00560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WL96_RS00565	COG0277	FAD linked oxidase domain protein
WL96_RS00575	COG0789	Transcriptional regulator
WL96_RS00585	COG0668	transmembrane transport
WL96_RS00590	COG0531	amino acid
WL96_RS00600	COG4302	ethanolamine ammonia-lyase activity
WL96_RS00605	COG0583	DNA-binding transcription factor activity
WL96_RS00610	COG0477	Major facilitator Superfamily
WL96_RS00620	COG1012	belongs to the aldehyde dehydrogenase family
WL96_RS00640	COG0028	Belongs to the TPP enzyme family
WL96_RS00655	COG1760	l-serine dehydratase
WL96_RS00665	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WL96_RS00665	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WL96_RS00670	COG0509	glycine decarboxylation via glycine cleavage system
WL96_RS00675	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WL96_RS00685	COG0673	inositol 2-dehydrogenase activity
WL96_RS00695	COG0210	DNA helicase
WL96_RS00700	COG3245	cytochrome
WL96_RS00735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WL96_RS00740	COG4106	trans-aconitate 2-methyltransferase activity
WL96_RS00800	COG0519	Catalyzes the synthesis of GMP from XMP
WL96_RS00815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WL96_RS00820	COG2916	Histone family protein nucleoid-structuring protein H-NS
WL96_RS00825	COG0438	transferase activity, transferring glycosyl groups
WL96_RS00845	COG1360	Flagellar Motor Protein
WL96_RS00850	COG0745	RESPONSE REGULATOR receiver
WL96_RS00860	COG0835	chemotaxis
WL96_RS00865	COG0840	transmembrane signaling receptor activity
WL96_RS00870	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WL96_RS00875	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
WL96_RS00885	COG0745	RESPONSE REGULATOR receiver
WL96_RS00890	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WL96_RS00910	COG3152	Membrane
WL96_RS00920	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WL96_RS00925	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WL96_RS00950	COG1950	PFAM Membrane protein of
WL96_RS00955	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
WL96_RS00995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WL96_RS01000	COG1522	sequence-specific DNA binding
WL96_RS01010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WL96_RS01025	COG0792	nuclease activity
WL96_RS01030	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WL96_RS01035	COG2823	Periplasmic or secreted lipoprotein
WL96_RS01055	COG2271	Major facilitator Superfamily
WL96_RS01065	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
WL96_RS01070	COG0577	efflux transmembrane transporter activity
WL96_RS01080	COG1136	(ABC) transporter
WL96_RS01095	COG2084	Dehydrogenase
WL96_RS01100	COG1280	lysine exporter protein (LysE YggA)
WL96_RS01105	COG2814	Major facilitator Superfamily
WL96_RS01110	COG0583	DNA-binding transcription factor activity
WL96_RS01130	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WL96_RS01140	COG1881	PFAM PEBP family protein
WL96_RS01145	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WL96_RS01150	COG0281	malic enzyme
WL96_RS01150	COG0280	phosphate acetyltransferase
WL96_RS01170	COG1522	sequence-specific DNA binding
WL96_RS01190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WL96_RS01195	COG2151	metal-sulfur cluster biosynthetic enzyme
WL96_RS01200	COG3396	Phenylacetate-CoA oxygenase
WL96_RS01205	COG3460	Phenylacetate-CoA oxygenase
WL96_RS01210	COG3396	Phenylacetate-CoA oxygenase
WL96_RS01245	COG3547	Transposase (IS116 IS110 IS902 family)
WL96_RS01270	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WL96_RS01280	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WL96_RS01290	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WL96_RS01295	COG0081	regulation of translation
WL96_RS01305	COG0222	ribosome binding
WL96_RS01310	COG0085	RNA polymerase activity
WL96_RS01315	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WL96_RS01320	COG0514	ATP-dependent DNA helicase (RecQ)
WL96_RS01340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WL96_RS01350	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WL96_RS01365	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WL96_RS01395	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
WL96_RS01400	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WL96_RS01410	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WL96_RS01415	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WL96_RS01425	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WL96_RS01445	COG0200	Binds to the 23S rRNA
WL96_RS01450	COG0201	protein transport
WL96_RS01465	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WL96_RS01475	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WL96_RS01495	COG4232	protein-disulfide reductase activity
WL96_RS01505	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WL96_RS01515	COG1333	cytochrome c biogenesis protein
WL96_RS01520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WL96_RS01525	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WL96_RS01530	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
WL96_RS01540	COG1965	Belongs to the frataxin family
WL96_RS01575	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WL96_RS01580	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WL96_RS01585	COG1653	transport
WL96_RS01590	COG1175	transmembrane transport
WL96_RS01595	COG0395	ABC-type sugar transport system, permease component
WL96_RS01605	COG0584	glycerophosphoryl diester phosphodiesterase
WL96_RS01620	COG0070	glutamate synthase
WL96_RS01620	COG0067	glutamate synthase
WL96_RS01620	COG0069	glutamate synthase activity
WL96_RS01640	COG4178	(ABC) transporter
WL96_RS01665	COG1127	ABC transporter
WL96_RS01670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WL96_RS01675	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WL96_RS01695	COG1131	(ABC) transporter
WL96_RS01700	COG0842	Transport permease protein
WL96_RS01715	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WL96_RS01730	COG0131	Imidazoleglycerol-phosphate dehydratase
WL96_RS01735	COG2095	MarC family integral membrane protein
WL96_RS01740	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WL96_RS01745	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
WL96_RS01750	COG0107	imidazoleglycerol-phosphate synthase activity
WL96_RS01755	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WL96_RS01760	COG0140	phosphoribosyl-ATP diphosphatase activity
WL96_RS01775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WL96_RS01780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WL96_RS01785	COG0805	protein transport
WL96_RS01790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WL96_RS01795	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WL96_RS01800	COG0723	plastoquinol--plastocyanin reductase activity
WL96_RS01805	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WL96_RS01810	COG2857	Cytochrome c1
WL96_RS01815	COG0625	glutathione transferase activity
WL96_RS01820	COG2969	positive regulation of protein catabolic process
WL96_RS01850	COG5377	YqaJ viral recombinase family
WL96_RS01875	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WL96_RS01885	COG1401	restriction endodeoxyribonuclease activity
WL96_RS01900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WL96_RS01920	COG3328	transposase activity
WL96_RS01935	COG3328	transposase activity
WL96_RS02040	COG0308	aminopeptidase N
WL96_RS02065	COG1309	transcriptional regulator
WL96_RS02080	COG0443	Heat shock 70 kDa protein
WL96_RS02085	COG1278	Cold shock
WL96_RS02090	COG0531	amino acid
WL96_RS02095	COG3384	dioxygenase
WL96_RS02105	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WL96_RS02110	COG2890	protein-(glutamine-N5) methyltransferase activity
WL96_RS02115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WL96_RS02120	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
WL96_RS02135	COG0006	proline dipeptidase activity
WL96_RS02140	COG1335	isochorismatase
WL96_RS02150	COG0488	(ABC) transporter
WL96_RS02165	COG0012	GTP binding
WL96_RS02170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WL96_RS02175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WL96_RS02190	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WL96_RS02200	COG0134	indole-3-glycerol-phosphate synthase activity
WL96_RS02205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WL96_RS02210	COG0512	Glutamine amidotransferase of anthranilate synthase
WL96_RS02220	COG0546	phosphoglycolate phosphatase activity
WL96_RS02225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WL96_RS02230	COG2967	ApaG domain
WL96_RS02235	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WL96_RS02245	COG2050	protein possibly involved in aromatic compounds catabolism
WL96_RS02250	COG1024	Enoyl-CoA hydratase
WL96_RS02265	COG1024	Enoyl-CoA hydratase
WL96_RS02300	COG0318	PFAM AMP-dependent synthetase and ligase
WL96_RS02305	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WL96_RS02310	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
WL96_RS02315	COG2001	Belongs to the MraZ family
WL96_RS02320	COG0275	rRNA processing
WL96_RS02325	COG3116	cell division
WL96_RS02335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WL96_RS02340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WL96_RS02345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WL96_RS02350	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WL96_RS02360	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WL96_RS02365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WL96_RS02370	COG1181	Belongs to the D-alanine--D-alanine ligase family
WL96_RS02375	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WL96_RS02390	COG0678	peroxiredoxin activity
WL96_RS02395	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WL96_RS02405	COG0653	protein targeting
WL96_RS02420	COG0494	nUDIX hydrolase
WL96_RS02425	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
WL96_RS02430	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
WL96_RS02440	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WL96_RS02455	COG4536	flavin adenine dinucleotide binding
WL96_RS02470	COG0142	geranyltranstransferase activity
WL96_RS02485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WL96_RS02490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
WL96_RS02500	COG0494	nUDIX hydrolase
WL96_RS02505	COG0442	prolyl-tRNA aminoacylation
WL96_RS02510	COG2095	MarC family integral membrane protein
WL96_RS02515	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
WL96_RS02520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WL96_RS02560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WL96_RS02565	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
WL96_RS02575	COG2264	protein methyltransferase activity
WL96_RS02580	COG0439	Biotin carboxylase
WL96_RS02585	COG0511	ligase activity, forming carbon-carbon bonds
WL96_RS02590	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WL96_RS02595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WL96_RS02605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WL96_RS02610	COG3150	esterase
WL96_RS02615	COG0557	exoribonuclease II activity
WL96_RS02620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WL96_RS02625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WL96_RS02640	COG1414	Transcriptional regulator
WL96_RS02645	COG3734	2-keto-3-deoxy-galactonokinase
WL96_RS02650	COG0800	Aldolase
WL96_RS02655	COG1028	Short-chain dehydrogenase reductase Sdr
WL96_RS02665	COG1129	ABC transporter
WL96_RS02685	COG0284	orotidine-5'-phosphate decarboxylase activity
WL96_RS02690	COG1546	Belongs to the CinA family
WL96_RS02695	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WL96_RS02710	COG4290	ribonuclease
WL96_RS02720	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WL96_RS02730	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WL96_RS02735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WL96_RS02740	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WL96_RS02750	COG1301	dicarboxylic acid transport
WL96_RS02755	COG4266	Belongs to the allantoicase family
WL96_RS02760	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
WL96_RS02765	COG0735	belongs to the Fur family
WL96_RS02770	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WL96_RS02775	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WL96_RS02790	COG0495	leucyl-tRNA aminoacylation
WL96_RS02795	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
WL96_RS02800	COG1466	dna polymerase III delta subunit
WL96_RS02805	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
WL96_RS02810	COG1981	membrane
WL96_RS02825	COG0800	Aldolase
WL96_RS02835	COG3265	gluconokinase activity
WL96_RS02845	COG0583	DNA-binding transcription factor activity
WL96_RS02850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WL96_RS02860	COG0765	amino acid transport
WL96_RS02865	COG0765	amino acid transport
WL96_RS02870	COG1126	abc transporter atp-binding protein
WL96_RS02880	COG0121	glutamine amidotransferase
WL96_RS02885	COG0418	dihydroorotase activity
WL96_RS02910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WL96_RS02915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WL96_RS02920	COG0316	Belongs to the HesB IscA family
WL96_RS02925	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WL96_RS02935	COG1490	D-aminoacyl-tRNA deacylase activity
WL96_RS02940	COG0588	phosphoglycerate mutase activity
WL96_RS02950	COG2255	four-way junction helicase activity
WL96_RS02955	COG0632	four-way junction helicase activity
WL96_RS02960	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
WL96_RS02965	COG0138	bifunctional purine biosynthesis protein purh
WL96_RS02970	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
WL96_RS02980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WL96_RS02985	COG0006	proline dipeptidase activity
WL96_RS02990	COG0625	glutathione transferase activity
WL96_RS02995	COG0069	glutamate synthase activity
WL96_RS03000	COG0482	sulfurtransferase activity
WL96_RS03050	COG3008	intermembrane lipid transfer
WL96_RS03050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WL96_RS03055	COG2995	paraquat-inducible protein a
WL96_RS03070	COG2353	YceI-like domain
WL96_RS03075	COG2353	YceI-like domain
WL96_RS03085	COG0793	Belongs to the peptidase S41A family
WL96_RS03090	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WL96_RS03095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WL96_RS03100	COG1862	Preprotein translocase
WL96_RS03105	COG0343	queuine tRNA-ribosyltransferase activity
WL96_RS03110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WL96_RS03115	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WL96_RS03130	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
WL96_RS03135	COG0783	Belongs to the Dps family
WL96_RS03140	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WL96_RS03155	COG0247	lactate metabolic process
WL96_RS03160	COG0277	FAD linked oxidase domain protein
WL96_RS03165	COG0277	FAD linked oxidase domain protein
WL96_RS03170	COG0277	FAD linked oxidase domain protein
WL96_RS03175	COG2096	Adenosyltransferase
WL96_RS03180	COG1017	nitric oxide dioxygenase activity
WL96_RS03180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WL96_RS03185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WL96_RS03190	COG0312	modulator of DNA gyrase
WL96_RS03195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WL96_RS03205	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WL96_RS03210	COG0497	DNA recombination
WL96_RS03215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WL96_RS03220	COG1420	regulation of RNA biosynthetic process
WL96_RS03225	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WL96_RS03240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WL96_RS03250	COG0443	Heat shock 70 kDa protein
WL96_RS03255	COG0484	heat shock protein binding
WL96_RS03260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WL96_RS03260	COG0512	Glutamine amidotransferase of anthranilate synthase
WL96_RS03265	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WL96_RS03275	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WL96_RS03280	COG0617	tRNA 3'-terminal CCA addition
WL96_RS03290	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WL96_RS03295	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WL96_RS03305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WL96_RS03310	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WL96_RS03315	COG0586	Pfam SNARE associated Golgi protein
WL96_RS03320	COG0529	Catalyzes the synthesis of activated sulfate
WL96_RS03325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WL96_RS03330	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WL96_RS03350	COG0823	Involved in the tonB-independent uptake of proteins
WL96_RS03370	COG0824	Thioesterase
WL96_RS03375	COG4221	oxidoreductase activity
WL96_RS03385	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WL96_RS03430	COG0450	alkyl hydroperoxide reductase
WL96_RS03435	COG1960	acyl-CoA dehydrogenase activity
WL96_RS03455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WL96_RS03470	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
WL96_RS03485	COG2814	Major facilitator Superfamily
WL96_RS03490	COG0778	Nitroreductase
WL96_RS03495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WL96_RS03500	COG0583	DNA-binding transcription factor activity
WL96_RS03505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WL96_RS03510	COG4977	sequence-specific DNA binding
WL96_RS03530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WL96_RS03575	COG0730	response to heat
WL96_RS03635	COG0459	protein refolding
WL96_RS03645	COG1773	rubredoxin
WL96_RS03655	COG1678	Uncharacterized ACR, COG1678
WL96_RS03660	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WL96_RS03665	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
WL96_RS03670	COG0540	Belongs to the ATCase OTCase family
WL96_RS03675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
WL96_RS03720	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WL96_RS03740	COG1086	Polysaccharide biosynthesis protein
WL96_RS03755	COG0297	glycogen (starch) synthase activity
WL96_RS03785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WL96_RS03795	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WL96_RS03800	COG0438	transferase activity, transferring glycosyl groups
WL96_RS03835	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WL96_RS03840	COG0830	nickel cation binding
WL96_RS03845	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
WL96_RS03850	COG0804	urea catabolic process
WL96_RS03855	COG0832	Belongs to the urease beta subunit family
WL96_RS03865	COG0829	nickel cation binding
WL96_RS03875	COG1129	ABC transporter
WL96_RS03900	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WL96_RS03910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WL96_RS03925	COG1968	undecaprenyl-diphosphatase activity
WL96_RS03930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WL96_RS04070	COG0494	nUDIX hydrolase
WL96_RS04080	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
WL96_RS04090	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WL96_RS04100	COG0762	integral membrane protein
WL96_RS04120	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WL96_RS04130	COG0436	Aminotransferase
WL96_RS04135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WL96_RS04140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WL96_RS04160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WL96_RS04160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WL96_RS04165	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WL96_RS04175	COG2814	Major facilitator Superfamily
WL96_RS04185	COG0363	glucosamine-6-phosphate deaminase activity
WL96_RS04190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WL96_RS04200	COG1175	transmembrane transport
WL96_RS04205	COG0395	ABC-type sugar transport system, permease component
WL96_RS04210	COG3842	ATPase activity
WL96_RS04215	COG2860	membrane
WL96_RS04220	COG1193	negative regulation of DNA recombination
WL96_RS04225	COG0492	ferredoxin-NADP+ reductase activity
WL96_RS04230	COG1674	ftsk spoiiie
WL96_RS04235	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WL96_RS04240	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WL96_RS04250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WL96_RS04275	COG0850	regulation of cytokinetic process
WL96_RS04280	COG2894	cell division
WL96_RS04285	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WL96_RS04300	COG0859	PFAM glycosyl transferase family 9
WL96_RS04310	COG0477	Major facilitator Superfamily
WL96_RS04335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WL96_RS04340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WL96_RS04345	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
WL96_RS04350	COG1561	YicC-like family, N-terminal region
WL96_RS04365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WL96_RS04390	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WL96_RS04405	COG1278	Cold shock
WL96_RS04410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WL96_RS04410	COG1199	ATP-dependent helicase activity
WL96_RS04425	COG4772	TonB-dependent receptor
WL96_RS04450	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
WL96_RS04455	COG0308	aminopeptidase N
WL96_RS04465	COG2119	membrane
WL96_RS04470	COG0402	S-adenosylhomocysteine deaminase activity
WL96_RS04475	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WL96_RS04500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WL96_RS04535	COG3383	formate dehydrogenase (NAD+) activity
WL96_RS04550	COG1910	domain protein
WL96_RS04570	COG0546	phosphoglycolate phosphatase activity
WL96_RS04575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WL96_RS04595	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WL96_RS04605	COG0287	Prephenate dehydrogenase
WL96_RS04610	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WL96_RS04615	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WL96_RS04625	COG0776	regulation of translation
WL96_RS04635	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WL96_RS04645	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WL96_RS04650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WL96_RS04665	COG2951	lytic endotransglycosylase activity
WL96_RS04670	COG0123	including yeast histone deacetylase and acetoin utilization protein
WL96_RS04675	COG2267	carboxylic ester hydrolase activity
WL96_RS04680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WL96_RS04685	COG2011	ABC-type metal ion transport system permease component
WL96_RS04705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WL96_RS04735	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WL96_RS04740	COG0336	Belongs to the RNA methyltransferase TrmD family
WL96_RS04745	COG0335	large ribosomal subunit rRNA binding
WL96_RS04750	COG0494	nUDIX hydrolase
WL96_RS04770	COG0501	Belongs to the peptidase M48B family
WL96_RS04775	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
WL96_RS04780	COG0521	Mo-molybdopterin cofactor biosynthetic process
WL96_RS04785	COG3028	Belongs to the UPF0307 family
WL96_RS04790	COG0312	modulator of DNA gyrase
WL96_RS04805	COG2204	response regulator
WL96_RS04810	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WL96_RS04835	COG0114	fumarate hydratase activity
WL96_RS04865	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
WL96_RS04875	COG3045	CreA protein
WL96_RS04890	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WL96_RS04895	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WL96_RS04915	COG1322	Protein conserved in bacteria
WL96_RS04930	COG0303	'Molybdopterin
WL96_RS04935	COG0746	molybdenum cofactor guanylyltransferase activity
WL96_RS04940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WL96_RS04945	COG1530	ribonuclease E activity
WL96_RS04955	COG0546	phosphoglycolate phosphatase activity
WL96_RS04965	COG0616	signal peptide processing
WL96_RS04980	COG1399	metal-binding, possibly nucleic acid-binding protein
WL96_RS04990	COG0416	fatty acid biosynthetic process
WL96_RS04995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WL96_RS05015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WL96_RS05025	COG1595	DNA-templated transcription, initiation
WL96_RS05040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WL96_RS05050	COG0481	GTPase activity
WL96_RS05055	COG0681	Belongs to the peptidase S26 family
WL96_RS05060	COG0571	ribonuclease III activity
WL96_RS05065	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WL96_RS05075	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WL96_RS05080	COG0736	holo-[acyl-carrier-protein] synthase activity
WL96_RS05085	COG1472	Belongs to the glycosyl hydrolase 3 family
WL96_RS05095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WL96_RS05105	COG0322	excinuclease ABC activity
WL96_RS05150	COG0024	Methionine aminopeptidase
WL96_RS05155	COG1956	GAF domain-containing protein
WL96_RS05170	COG2153	protein acetylation
WL96_RS05185	COG1999	signal sequence binding
WL96_RS05195	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
WL96_RS05200	COG1132	(ABC) transporter
WL96_RS05205	COG0438	transferase activity, transferring glycosyl groups
WL96_RS05235	COG3511	phospholipase C
WL96_RS05245	COG0596	Alpha beta hydrolase
WL96_RS05250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WL96_RS05265	COG3394	polysaccharide catabolic process
WL96_RS05300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WL96_RS05315	COG1012	belongs to the aldehyde dehydrogenase family
WL96_RS05320	COG3724	N-succinylarginine dihydrolase activity
WL96_RS05330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WL96_RS05370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WL96_RS05385	COG0004	ammonium transporteR
WL96_RS05400	COG1959	2 iron, 2 sulfur cluster binding
WL96_RS05410	COG1522	sequence-specific DNA binding
WL96_RS05415	COG1289	transmembrane transporter activity
WL96_RS05420	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WL96_RS05425	COG1074	ATP-dependent DNA helicase activity
WL96_RS05430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WL96_RS05440	COG2200	EAL domain
WL96_RS05460	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
WL96_RS05470	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
WL96_RS05475	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WL96_RS05480	COG0697	spore germination
WL96_RS05485	COG2814	Major facilitator Superfamily
WL96_RS05490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WL96_RS05495	COG3842	ATPase activity
WL96_RS05500	COG1177	transmembrane transport
WL96_RS05510	COG1840	ABC-type Fe3 transport system, periplasmic component
WL96_RS05515	COG1609	Transcriptional regulator
WL96_RS05545	COG3328	transposase activity
WL96_RS05565	COG3328	transposase activity
WL96_RS05570	COG3547	Transposase (IS116 IS110 IS902 family)
WL96_RS05575	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WL96_RS05580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WL96_RS05590	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WL96_RS05595	COG0583	DNA-binding transcription factor activity
WL96_RS05600	COG0477	Major facilitator Superfamily
WL96_RS05615	COG2814	Major facilitator Superfamily
WL96_RS05620	COG0583	DNA-binding transcription factor activity
WL96_RS05635	COG0583	DNA-binding transcription factor activity
WL96_RS05640	COG1253	flavin adenine dinucleotide binding
WL96_RS05660	COG0583	DNA-binding transcription factor activity
WL96_RS05680	COG3052	prosthetic group binding
WL96_RS05700	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
WL96_RS05735	COG0477	Major facilitator Superfamily
WL96_RS05740	COG1742	UPF0060 membrane protein
WL96_RS05745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WL96_RS05750	COG0328	RNA-DNA hybrid ribonuclease activity
WL96_RS05755	COG2226	methyltransferase
WL96_RS05760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WL96_RS05765	COG1388	LysM domain
WL96_RS05765	COG0741	lytic transglycosylase activity
WL96_RS05770	COG2223	nitrite transmembrane transporter activity
WL96_RS05775	COG0505	Belongs to the CarA family
WL96_RS05785	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WL96_RS05790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WL96_RS05800	COG1534	Rna-binding protein
WL96_RS05805	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WL96_RS05810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WL96_RS05820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WL96_RS05825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WL96_RS05830	COG0573	inorganic phosphate transmembrane transporter activity
WL96_RS05835	COG0581	inorganic phosphate transmembrane transporter activity
WL96_RS05850	COG0745	RESPONSE REGULATOR receiver
WL96_RS05860	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WL96_RS05895	COG0534	Mate efflux family protein
WL96_RS05905	COG4942	peptidase
WL96_RS05955	COG1733	regulation of RNA biosynthetic process
WL96_RS05960	COG0702	epimerase
WL96_RS05995	COG5377	YqaJ viral recombinase family
WL96_RS06065	COG2801	Transposase and inactivated derivatives
WL96_RS06085	COG2205	protein histidine kinase activity
WL96_RS06090	COG0745	RESPONSE REGULATOR receiver
WL96_RS06110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WL96_RS06120	COG4589	Belongs to the CDS family
WL96_RS06130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WL96_RS06135	COG2267	carboxylic ester hydrolase activity
WL96_RS06140	COG2453	phosphatase
WL96_RS06140	COG0671	phosphoesterase, PA-phosphatase related
WL96_RS06150	COG1215	transferase activity, transferring glycosyl groups
WL96_RS06155	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
WL96_RS06185	COG2194	sulfuric ester hydrolase activity
WL96_RS06195	COG1741	Belongs to the pirin family
WL96_RS06205	COG0025	NhaP-type Na H and K H
WL96_RS06235	COG1858	cytochrome C peroxidase
WL96_RS06250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WL96_RS06265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WL96_RS06270	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WL96_RS06280	COG0477	Major facilitator Superfamily
WL96_RS06285	COG2816	NAD+ diphosphatase activity
WL96_RS06290	COG0824	Thioesterase
WL96_RS06305	COG1129	ABC transporter
WL96_RS06315	COG1028	Short-chain dehydrogenase reductase Sdr
WL96_RS06325	COG3718	enzyme involved in inositol metabolism
WL96_RS06335	COG3962	Belongs to the TPP enzyme family
WL96_RS06350	COG1129	ABC transporter
WL96_RS06355	COG1172	Belongs to the binding-protein-dependent transport system permease family
WL96_RS06360	COG0673	inositol 2-dehydrogenase activity
WL96_RS06365	COG0673	inositol 2-dehydrogenase activity
WL96_RS06370	COG1737	Transcriptional regulator
WL96_RS06385	COG0425	Belongs to the sulfur carrier protein TusA family
WL96_RS06395	COG0745	RESPONSE REGULATOR receiver
WL96_RS06415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WL96_RS06420	COG0525	valine-tRNA ligase activity
WL96_RS06425	COG0210	DNA helicase
WL96_RS06430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WL96_RS06435	COG2223	nitrite transmembrane transporter activity
WL96_RS06440	COG0840	transmembrane signaling receptor activity
WL96_RS06465	COG0583	DNA-binding transcription factor activity
WL96_RS06475	COG0277	FAD linked oxidase domain protein
WL96_RS06490	COG1295	ribonuclease BN
WL96_RS06505	COG0477	Major facilitator Superfamily
WL96_RS06510	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WL96_RS06520	COG2271	Major facilitator Superfamily
WL96_RS06525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WL96_RS06535	COG1028	Short-chain dehydrogenase reductase Sdr
WL96_RS06560	COG1028	Short-chain dehydrogenase reductase Sdr
WL96_RS06575	COG0583	DNA-binding transcription factor activity
WL96_RS06585	COG0251	oxidation-reduction process
WL96_RS06590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WL96_RS06600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WL96_RS06605	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WL96_RS06620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WL96_RS06630	COG0776	regulation of translation
WL96_RS06645	COG0500	methyltransferase
WL96_RS06655	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WL96_RS06685	COG0583	DNA-binding transcription factor activity
WL96_RS06690	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WL96_RS06700	COG0779	Required for maturation of 30S ribosomal subunits
WL96_RS06705	COG0195	Participates in both transcription termination and antitermination
WL96_RS06705	COG2251	uridine kinase activity
WL96_RS06710	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WL96_RS06715	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WL96_RS06725	COG2814	Major facilitator Superfamily
WL96_RS06730	COG1566	PFAM secretion protein HlyD family protein
WL96_RS06740	COG1846	Transcriptional regulator
WL96_RS06745	COG1217	gtp-binding protein TYPA
WL96_RS06750	COG0567	Dehydrogenase, E1 component
WL96_RS06755	COG0508	dehydrogenase complex catalyzes the overall conversion of
WL96_RS06760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WL96_RS06765	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WL96_RS06815	COG4964	Belongs to the GSP D family
WL96_RS06880	COG0318	PFAM AMP-dependent synthetase and ligase
WL96_RS06890	COG2814	Major facilitator Superfamily
WL96_RS06910	COG1879	ABC-type sugar transport system periplasmic component
WL96_RS06915	COG1172	Belongs to the binding-protein-dependent transport system permease family
WL96_RS06925	COG1940	carbohydrate kinase activity
WL96_RS06945	COG0557	exoribonuclease II activity
WL96_RS06950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WL96_RS06955	COG3023	N-Acetylmuramoyl-L-alanine amidase
WL96_RS06960	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
WL96_RS06965	COG1802	Transcriptional regulator
WL96_RS06970	COG0673	inositol 2-dehydrogenase activity
WL96_RS06975	COG0765	amino acid transport
WL96_RS06980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WL96_RS06985	COG0167	dihydroorotate dehydrogenase activity
WL96_RS06990	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WL96_RS06995	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WL96_RS07010	COG4702	Belongs to the UPF0303 family
WL96_RS07035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WL96_RS07040	COG1116	anion transmembrane transporter activity
WL96_RS07105	COG0305	Participates in initiation and elongation during chromosome replication
WL96_RS07130	COG1802	Transcriptional regulator
WL96_RS07130	COG4626	Terminase
WL96_RS07175	COG4386	tail sheath protein
WL96_RS07210	COG4381	Mu-like prophage protein gp46
WL96_RS07270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WL96_RS07330	COG0419	ATPase involved in DNA repair
WL96_RS07335	COG1674	ftsk spoiiie
WL96_RS07450	COG5410	chromosome segregation
WL96_RS07520	COG1705	Flagellar rod assembly protein muramidase FlgJ
WL96_RS07520	COG1388	LysM domain
WL96_RS07570	COG2755	lipolytic protein G-D-S-L family
WL96_RS07570	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WL96_RS07655	COG0667	Aldo Keto reductase
WL96_RS07665	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
WL96_RS07670	COG0701	Predicted permease
WL96_RS07705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WL96_RS07710	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WL96_RS07715	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WL96_RS07720	COG4208	sulfate ABC transporter
WL96_RS07725	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WL96_RS07730	COG0583	DNA-binding transcription factor activity
WL96_RS07735	COG1879	ABC-type sugar transport system periplasmic component
WL96_RS07740	COG1129	ABC transporter
WL96_RS07745	COG1172	Belongs to the binding-protein-dependent transport system permease family
WL96_RS07750	COG1609	Transcriptional regulator
WL96_RS07755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WL96_RS07765	COG2766	serine protein kinase
WL96_RS07770	COG2718	Belongs to the UPF0229 family
WL96_RS07775	COG2719	SpoVR family
WL96_RS07780	COG0477	Major facilitator Superfamily
WL96_RS07790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WL96_RS07795	COG0765	amino acid transport
WL96_RS07800	COG0765	amino acid transport
WL96_RS07805	COG0739	heme binding
WL96_RS07810	COG1309	transcriptional regulator
WL96_RS07820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WL96_RS07845	COG1120	ATPase activity
WL96_RS07880	COG3486	L-lysine 6-monooxygenase (NADPH) activity
WL96_RS07885	COG4774	siderophore transport
WL96_RS07890	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WL96_RS07905	COG1473	amidohydrolase
WL96_RS07910	COG1797	cobyrinic acid a,c-diamide synthase activity
WL96_RS07930	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
WL96_RS07955	COG1671	Belongs to the UPF0178 family
WL96_RS07990	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
WL96_RS07995	COG2099	Precorrin-6x reductase
WL96_RS08010	COG2807	transmembrane transport
WL96_RS08015	COG1846	Transcriptional regulator
WL96_RS08020	COG0625	glutathione transferase activity
WL96_RS08045	COG2070	2-Nitropropane dioxygenase
WL96_RS08065	COG0531	amino acid
WL96_RS08095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WL96_RS08105	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
WL96_RS08120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WL96_RS08135	COG0598	Magnesium transport protein CorA
WL96_RS08180	COG1609	Transcriptional regulator
WL96_RS08185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WL96_RS08195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WL96_RS08210	COG2855	membrane
WL96_RS08215	COG0038	chloride channel
WL96_RS08230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WL96_RS08260	COG0730	response to heat
WL96_RS08260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WL96_RS08265	COG1177	transmembrane transport
WL96_RS08270	COG1176	ABC-type spermidine putrescine transport system, permease component I
WL96_RS08275	COG3842	ATPase activity
WL96_RS08280	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WL96_RS08290	COG3047	cAMP biosynthetic process
WL96_RS08295	COG2070	2-Nitropropane dioxygenase
WL96_RS08310	COG1522	sequence-specific DNA binding
WL96_RS08325	COG2801	Transposase and inactivated derivatives
WL96_RS08375	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WL96_RS08375	COG0546	phosphoglycolate phosphatase activity
WL96_RS08400	COG0488	(ABC) transporter
WL96_RS08405	COG2982	Protein involved in outer membrane biogenesis
WL96_RS08415	COG0390	transport system, permease component
WL96_RS08430	COG0583	DNA-binding transcription factor activity
WL96_RS08435	COG0560	Phosphoserine phosphatase
WL96_RS08440	COG0626	cystathionine gamma-synthase activity
WL96_RS08455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WL96_RS08470	COG1028	Short-chain dehydrogenase reductase Sdr
WL96_RS08475	COG0183	Belongs to the thiolase family
WL96_RS08480	COG3243	poly(R)-hydroxyalkanoic acid synthase
WL96_RS08490	COG0564	pseudouridine synthase activity
WL96_RS08500	COG1199	ATP-dependent helicase activity
WL96_RS08515	COG2183	response to ionizing radiation
WL96_RS08520	COG3158	transport of potassium into the cell
WL96_RS08525	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
WL96_RS08535	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
WL96_RS08545	COG0330	HflC and HflK could
WL96_RS08550	COG0330	HflC and HflK could
WL96_RS08555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WL96_RS08565	COG1160	GTP binding
WL96_RS08570	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WL96_RS08580	COG0124	histidyl-tRNA synthetase
WL96_RS08585	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
WL96_RS08595	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WL96_RS08605	COG0670	Belongs to the BI1 family
WL96_RS08610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WL96_RS08635	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WL96_RS08640	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
WL96_RS08650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WL96_RS08655	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WL96_RS08660	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WL96_RS08665	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WL96_RS08680	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WL96_RS08685	COG0789	Transcriptional regulator
WL96_RS08690	COG0477	Major facilitator Superfamily
WL96_RS08695	COG3228	Belongs to the MtfA family
WL96_RS08700	COG0254	rRNA binding
WL96_RS08710	COG0534	Mate efflux family protein
WL96_RS08715	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WL96_RS08725	COG0022	dehydrogenase e1 component
WL96_RS08730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WL96_RS08735	COG1028	Short-chain dehydrogenase reductase Sdr
WL96_RS08740	COG3199	ATP-NAD kinase
WL96_RS08745	COG3284	Transcriptional regulator
WL96_RS08770	COG0542	response to heat
WL96_RS08775	COG1959	2 iron, 2 sulfur cluster binding
WL96_RS08780	COG2346	COG2346, Truncated hemoglobins
WL96_RS08785	COG0314	molybdopterin synthase activity
WL96_RS08790	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WL96_RS08810	COG0436	Aminotransferase
WL96_RS08820	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WL96_RS08825	COG2076	Multidrug Resistance protein
WL96_RS08830	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WL96_RS08845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WL96_RS08845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WL96_RS08850	COG0726	polysaccharide deacetylase
WL96_RS08855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WL96_RS08860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WL96_RS08865	COG0791	NLP P60 protein
WL96_RS08870	COG0306	phosphate transporter
WL96_RS08880	COG0305	Participates in initiation and elongation during chromosome replication
WL96_RS08885	COG0359	binds to the 23S rRNA
WL96_RS08890	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WL96_RS08895	COG2965	DNA replication, synthesis of RNA primer
WL96_RS08900	COG0360	Binds together with S18 to 16S ribosomal RNA
WL96_RS08905	COG0583	DNA-binding transcription factor activity
WL96_RS08910	COG3960	tartronate-semialdehyde synthase activity
WL96_RS08915	COG3622	Belongs to the hyi family
WL96_RS08920	COG2084	Dehydrogenase
WL96_RS08925	COG1652	LysM domain
WL96_RS08930	COG0252	asparaginase activity
WL96_RS08950	COG0438	transferase activity, transferring glycosyl groups
WL96_RS08975	COG0084	hydrolase, TatD family'
WL96_RS08985	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WL96_RS08990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WL96_RS09005	COG2153	protein acetylation
WL96_RS09040	COG2814	Major facilitator Superfamily
WL96_RS09065	COG2199	diguanylate cyclase activity
WL96_RS09070	COG0183	Belongs to the thiolase family
WL96_RS09075	COG1335	isochorismatase
WL96_RS09085	COG0318	PFAM AMP-dependent synthetase and ligase
WL96_RS09090	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WL96_RS09095	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WL96_RS09100	COG2917	probably involved in intracellular septation
WL96_RS09110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WL96_RS09120	COG0047	phosphoribosylformylglycinamidine synthase activity
WL96_RS09120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WL96_RS09130	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WL96_RS09130	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WL96_RS09140	COG4181	ATPase activity
WL96_RS09165	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WL96_RS09170	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WL96_RS09175	COG0740	serine-type endopeptidase activity
WL96_RS09180	COG0544	peptidyl-prolyl cis-trans isomerase activity
WL96_RS09185	COG1929	Belongs to the glycerate kinase type-1 family
WL96_RS09195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WL96_RS09245	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WL96_RS09250	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
WL96_RS09255	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WL96_RS09260	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WL96_RS09290	COG1970	mechanosensitive ion channel activity
WL96_RS09305	COG3360	Dodecin
WL96_RS09320	COG2351	hydroxyisourate hydrolase activity
WL96_RS09340	COG4266	Belongs to the allantoicase family
WL96_RS09345	COG3648	Uricase
WL96_RS09345	COG3195	allantoin biosynthetic process
WL96_RS09360	COG1953	Uracil, thiamine, allantoin
WL96_RS09365	COG1802	Transcriptional regulator
WL96_RS09370	COG1619	proteins homologs of microcin C7 resistance protein MccF
WL96_RS09375	COG0590	tRNA wobble adenosine to inosine editing
WL96_RS09385	COG0519	Catalyzes the synthesis of GMP from XMP
WL96_RS09385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WL96_RS09425	COG0697	spore germination
WL96_RS09450	COG0330	HflC and HflK could
WL96_RS09465	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WL96_RS09470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WL96_RS09475	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WL96_RS09480	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WL96_RS09485	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WL96_RS09495	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WL96_RS09500	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
WL96_RS09510	COG0750	zinc metalloprotease
WL96_RS09515	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WL96_RS09525	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WL96_RS09530	COG0233	cytoplasmic translational termination
WL96_RS09535	COG0528	UMP kinase activity
WL96_RS09540	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WL96_RS09545	COG0052	Belongs to the universal ribosomal protein uS2 family
WL96_RS09550	COG0024	Methionine aminopeptidase
WL96_RS09555	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
WL96_RS09560	COG1187	pseudouridine synthase activity
WL96_RS09565	COG0242	peptide deformylase activity
WL96_RS09570	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WL96_RS09600	COG1393	Belongs to the ArsC family
WL96_RS09605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WL96_RS09610	COG2890	protein-(glutamine-N5) methyltransferase activity
WL96_RS09620	COG0386	Belongs to the glutathione peroxidase family
WL96_RS09625	COG0488	(ABC) transporter
WL96_RS09645	COG0477	Major facilitator Superfamily
WL96_RS09660	COG1573	uracil-dna glycosylase
WL96_RS09680	COG0513	Belongs to the DEAD box helicase family
WL96_RS09685	COG2224	Isocitrate lyase
WL96_RS09695	COG0583	DNA-binding transcription factor activity
WL96_RS09705	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WL96_RS09760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WL96_RS09765	COG1752	Esterase of the alpha-beta hydrolase superfamily
WL96_RS09770	COG0791	NLP P60 protein
WL96_RS09775	COG4172	Belongs to the ABC transporter superfamily
WL96_RS09780	COG4239	(ABC) transporter, permease
WL96_RS09785	COG4174	ABC transporter (Permease)
WL96_RS09800	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WL96_RS09830	COG3328	transposase activity
WL96_RS09845	COG3328	transposase activity
WL96_RS09875	COG0527	aspartate kinase activity
WL96_RS09880	COG0037	tRNA processing
WL96_RS09885	COG0825	malonyl-CoA metabolic process
WL96_RS09895	COG0215	cysteine-tRNA ligase activity
WL96_RS09905	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WL96_RS09915	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WL96_RS09920	COG1045	serine acetyltransferase
WL96_RS09930	COG0483	inositol monophosphate 1-phosphatase activity
WL96_RS09935	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
WL96_RS09955	COG0625	glutathione transferase activity
WL96_RS09965	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WL96_RS09980	COG2850	peptidyl-arginine hydroxylation
WL96_RS09985	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
WL96_RS09990	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WL96_RS09995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WL96_RS10005	COG0180	Tryptophanyl-tRNA synthetase
WL96_RS10010	COG1994	Peptidase M50
WL96_RS10015	COG0009	L-threonylcarbamoyladenylate synthase
WL96_RS10020	COG0613	PHP domain protein
WL96_RS10025	COG0596	Alpha beta hydrolase
WL96_RS10030	COG2833	Protein of unknown function (DUF455)
WL96_RS10040	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WL96_RS10050	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WL96_RS10055	COG0148	phosphopyruvate hydratase activity
WL96_RS10060	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WL96_RS10065	COG0504	CTP synthase activity
WL96_RS10075	COG0658	competence protein
WL96_RS10075	COG2333	competence protein COMEC
WL96_RS10080	COG0084	hydrolase, TatD family'
WL96_RS10100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WL96_RS10105	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WL96_RS10125	COG0443	Heat shock 70 kDa protein
WL96_RS10130	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WL96_RS10135	COG0316	Belongs to the HesB IscA family
WL96_RS10140	COG0822	iron-sulfur transferase activity
WL96_RS10145	COG1104	cysteine desulfurase activity
WL96_RS10155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WL96_RS10175	COG1414	Transcriptional regulator
WL96_RS10190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WL96_RS10195	COG0508	dehydrogenase complex catalyzes the overall conversion of
WL96_RS10200	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WL96_RS10210	COG4566	intracellular signal transduction
WL96_RS10215	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WL96_RS10220	COG0339	signal peptide processing
WL96_RS10225	COG3547	Transposase (IS116 IS110 IS902 family)
WL96_RS10230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WL96_RS10235	COG1794	racemase activity, acting on amino acids and derivatives
WL96_RS10250	COG1505	serine-type exopeptidase activity
WL96_RS10265	COG0174	glutamine synthetase
WL96_RS10275	COG1058	Belongs to the CinA family
WL96_RS10275	COG1546	Belongs to the CinA family
WL96_RS10295	COG1643	Atp-dependent helicase
WL96_RS10300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WL96_RS10300	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WL96_RS10320	COG0174	glutamine synthetase
WL96_RS10325	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WL96_RS10350	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
WL96_RS10360	COG2986	histidine ammonia-lyase
WL96_RS10380	COG0583	DNA-binding transcription factor activity
WL96_RS10420	COG2310	stress, protein
WL96_RS10430	COG2304	oxidoreductase activity
WL96_RS10465	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WL96_RS10500	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WL96_RS10550	COG0672	)-iron permease
WL96_RS10555	COG4633	Protein conserved in bacteria
WL96_RS10565	COG0556	nucleotide-excision repair
WL96_RS10575	COG1028	Short-chain dehydrogenase reductase Sdr
WL96_RS10580	COG0667	Aldo Keto reductase
WL96_RS10585	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WL96_RS10645	COG2866	Carboxypeptidase
WL96_RS10650	COG3022	response to hydroperoxide
WL96_RS10660	COG0436	Aminotransferase
WL96_RS10665	COG0625	glutathione transferase activity
WL96_RS10670	COG1024	Enoyl-CoA hydratase
WL96_RS10675	COG0625	glutathione transferase activity
WL96_RS10690	COG1960	acyl-CoA dehydrogenase activity
WL96_RS10695	COG1960	acyl-CoA dehydrogenase activity
WL96_RS10715	COG1007	ATP synthesis coupled electron transport
WL96_RS10730	COG0713	ATP synthesis coupled electron transport
WL96_RS10740	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WL96_RS10745	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WL96_RS10750	COG1034	ATP synthesis coupled electron transport
WL96_RS10750	COG1034	ATP synthesis coupled electron transport
WL96_RS10760	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WL96_RS10765	COG0649	NAD binding
WL96_RS10770	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WL96_RS10780	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WL96_RS10795	COG0149	triose-phosphate isomerase activity
WL96_RS10805	COG1185	polyribonucleotide nucleotidyltransferase activity
WL96_RS10815	COG0683	leucine binding
WL96_RS10825	COG0288	reversible hydration of carbon dioxide
WL96_RS10830	COG0659	secondary active sulfate transmembrane transporter activity
WL96_RS10835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WL96_RS10840	COG1183	phosphatidylcholine synthase activity
WL96_RS10845	COG0688	phosphatidylethanolamine metabolic process
WL96_RS10860	COG0028	Belongs to the TPP enzyme family
WL96_RS10890	COG0438	transferase activity, transferring glycosyl groups
WL96_RS10910	COG1028	Short-chain dehydrogenase reductase Sdr
WL96_RS10915	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WL96_RS10925	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WL96_RS10945	COG2076	Multidrug Resistance protein
WL96_RS10955	COG0745	RESPONSE REGULATOR receiver
WL96_RS10960	COG2205	protein histidine kinase activity
WL96_RS10965	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
WL96_RS10970	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
WL96_RS10975	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
WL96_RS10990	COG1803	Methylglyoxal synthase
WL96_RS10995	COG1028	Short-chain dehydrogenase reductase Sdr
WL96_RS11000	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WL96_RS11005	COG0217	transcriptional regulatory protein
WL96_RS11010	COG0151	Belongs to the GarS family
WL96_RS11025	COG0799	negative regulation of ribosome biogenesis
WL96_RS11030	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WL96_RS11050	COG3171	Protein conserved in bacteria
WL96_RS11085	COG1216	Glycosyl transferase, family 2
WL96_RS11095	COG0859	PFAM glycosyl transferase family 9
WL96_RS11110	COG1054	Belongs to the UPF0176 family
WL96_RS11120	COG0513	Belongs to the DEAD box helicase family
WL96_RS11125	COG3895	Periplasmic Protein
WL96_RS11135	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
WL96_RS11145	COG1674	ftsk spoiiie
WL96_RS11150	COG2706	6-phosphogluconolactonase activity
WL96_RS11155	COG3387	PFAM Glycoside hydrolase 15-related
WL96_RS11165	COG1309	transcriptional regulator
WL96_RS11170	COG2878	Part of a membrane complex involved in electron transport
WL96_RS11175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WL96_RS11205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WL96_RS11215	COG3135	benzoate transporter
WL96_RS11220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WL96_RS11280	COG0697	spore germination
WL96_RS11285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WL96_RS11295	COG0384	phenazine biosynthesis protein PhzF
WL96_RS11335	COG0488	(ABC) transporter
WL96_RS11385	COG2814	Major facilitator Superfamily
WL96_RS11415	COG1116	anion transmembrane transporter activity
WL96_RS11420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WL96_RS11495	COG2827	Endonuclease containing a URI domain
WL96_RS11500	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WL96_RS11515	COG2271	Major facilitator Superfamily
WL96_RS11530	COG0181	hydroxymethylbilane synthase activity
WL96_RS11535	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WL96_RS11540	COG2226	methyltransferase
WL96_RS11550	COG0165	Argininosuccinate lyase
WL96_RS11555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WL96_RS11580	COG0489	protein tyrosine kinase activity
WL96_RS11585	COG2885	chlorophyll binding
WL96_RS11585	COG3047	cAMP biosynthetic process
WL96_RS11590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WL96_RS11590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WL96_RS11610	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
WL96_RS11615	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WL96_RS11620	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
WL96_RS11630	COG2259	Doxx family
WL96_RS11635	COG1492	cobalamin metabolic process
WL96_RS11645	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
WL96_RS11655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WL96_RS11665	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
WL96_RS11670	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
WL96_RS11675	COG1120	ATPase activity
WL96_RS11680	COG4139	cobalamin transport
WL96_RS11710	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WL96_RS11735	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WL96_RS11755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WL96_RS11755	COG1648	precorrin-2 dehydrogenase activity
WL96_RS11760	COG2895	sulfate adenylyltransferase (ATP) activity
WL96_RS11770	COG0175	sulfate reduction
WL96_RS11785	COG0583	DNA-binding transcription factor activity
WL96_RS11800	COG0582	viral genome integration into host DNA
WL96_RS11845	COG4133	protoheme IX ABC transporter activity
WL96_RS11860	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WL96_RS11875	COG1028	Short-chain dehydrogenase reductase Sdr
WL96_RS11885	COG1187	pseudouridine synthase activity
WL96_RS11900	COG0543	2 iron, 2 sulfur cluster binding
WL96_RS11900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WL96_RS11905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WL96_RS11910	COG0456	acetyltransferase
WL96_RS11945	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WL96_RS11950	COG1047	Peptidyl-prolyl cis-trans
WL96_RS11955	COG2003	Belongs to the UPF0758 family
WL96_RS11970	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WL96_RS11980	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
WL96_RS11990	COG3264	Mechanosensitive ion channel
WL96_RS11990	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
WL96_RS11995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WL96_RS11995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WL96_RS12000	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WL96_RS12005	COG0196	riboflavin kinase activity
WL96_RS12010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WL96_RS12015	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WL96_RS12020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WL96_RS12025	COG0756	dUTP diphosphatase activity
WL96_RS12035	COG1113	amino acid transport
WL96_RS12040	COG0542	response to heat
WL96_RS12050	COG1278	Cold shock
WL96_RS12090	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
WL96_RS12095	COG0656	L-ascorbic acid biosynthetic process
WL96_RS12100	COG2188	Transcriptional regulator
WL96_RS12105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WL96_RS12120	COG2814	Major facilitator Superfamily
WL96_RS12170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WL96_RS12175	COG1570	exodeoxyribonuclease VII activity
WL96_RS12180	COG1663	tetraacyldisaccharide 4'-kinase activity
WL96_RS12185	COG2835	tetraacyldisaccharide 4'-kinase activity
WL96_RS12190	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WL96_RS12195	COG0563	adenylate kinase activity
WL96_RS12205	COG0728	peptidoglycan biosynthetic process
WL96_RS12225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WL96_RS12230	COG1666	GTP binding
WL96_RS12235	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WL96_RS12240	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WL96_RS12245	COG0318	PFAM AMP-dependent synthetase and ligase
WL96_RS12250	COG4974	Belongs to the 'phage' integrase family
WL96_RS12260	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WL96_RS12265	COG0802	atpase or kinase
WL96_RS12270	COG0860	N-Acetylmuramoyl-L-alanine amidase
WL96_RS12280	COG1741	Belongs to the pirin family
WL96_RS12290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WL96_RS12295	COG0259	pyridoxamine-phosphate oxidase activity
WL96_RS12300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WL96_RS12310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WL96_RS12315	COG3391	amine dehydrogenase activity
WL96_RS12325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WL96_RS12330	COG1522	sequence-specific DNA binding
WL96_RS12335	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
WL96_RS12345	COG3483	tryptophan 2,3-dioxygenase activity
WL96_RS12350	COG0246	Mannitol dehydrogenase
WL96_RS12355	COG1070	Carbohydrate kinase
WL96_RS12365	COG3842	ATPase activity
WL96_RS12370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WL96_RS12380	COG4209	transmembrane transport
WL96_RS12390	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
WL96_RS12395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WL96_RS12405	COG0735	belongs to the Fur family
WL96_RS12415	COG1121	(ABC) transporter
WL96_RS12420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WL96_RS12425	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
WL96_RS12430	COG1070	Carbohydrate kinase
WL96_RS12435	COG2233	PERMEase
WL96_RS12445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WL96_RS12465	COG4977	sequence-specific DNA binding
WL96_RS12470	COG0489	protein tyrosine kinase activity
WL96_RS12470	COG3206	protein involved in exopolysaccharide biosynthesis
WL96_RS12490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WL96_RS12505	COG2027	D-alanyl-D-alanine carboxypeptidase
WL96_RS12520	COG0009	L-threonylcarbamoyladenylate synthase
WL96_RS12525	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WL96_RS12530	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WL96_RS12535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WL96_RS12545	COG0469	pyruvate kinase activity
WL96_RS12550	COG0126	phosphoglycerate kinase activity
WL96_RS12585	COG0429	hydrolase of the alpha beta-hydrolase fold
WL96_RS12595	COG4783	chaperone-mediated protein folding
WL96_RS12600	COG0315	cyclic pyranopterin monophosphate synthase activity
WL96_RS12630	COG4969	Belongs to the N-Me-Phe pilin family
WL96_RS12635	COG0861	Integral membrane protein TerC family
WL96_RS12640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WL96_RS12645	COG0045	succinate-CoA ligase (ADP-forming) activity
WL96_RS12655	COG2137	regulation of response to DNA damage stimulus
WL96_RS12660	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WL96_RS12735	COG0583	DNA-binding transcription factor activity
WL96_RS12740	COG4977	sequence-specific DNA binding
WL96_RS12770	COG2186	Transcriptional regulator
WL96_RS12775	COG4948	Mandelate Racemase Muconate Lactonizing
WL96_RS12785	COG2863	cytochrome
WL96_RS12795	COG0513	Belongs to the DEAD box helicase family
WL96_RS12835	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WL96_RS12840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WL96_RS12845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WL96_RS12850	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WL96_RS12855	COG1396	sequence-specific DNA binding
WL96_RS12860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WL96_RS12865	COG1702	phosphate starvation-inducible protein PhoH
WL96_RS12875	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
WL96_RS12885	COG0815	Transfers the fatty acyl group on membrane lipoproteins
WL96_RS12895	COG0752	glycyl-tRNA synthetase alpha subunit
WL96_RS12900	COG0751	glycine-tRNA ligase activity
WL96_RS12905	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WL96_RS12910	COG0204	Acyl-transferase
WL96_RS12930	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WL96_RS12935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WL96_RS12945	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WL96_RS12960	COG5265	(ABC) transporter
WL96_RS12975	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WL96_RS12985	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WL96_RS13005	COG1024	Enoyl-CoA hydratase
WL96_RS13010	COG0183	Belongs to the thiolase family
WL96_RS13015	COG1024	Enoyl-CoA hydratase
WL96_RS13015	COG1250	3-hydroxyacyl-CoA dehydrogenase
WL96_RS13020	COG1960	acyl-CoA dehydrogenase activity
WL96_RS13035	COG0494	nUDIX hydrolase
WL96_RS13040	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WL96_RS13055	COG0500	methyltransferase
WL96_RS13075	COG2226	methyltransferase
WL96_RS13095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WL96_RS13100	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WL96_RS13100	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WL96_RS13105	COG0251	oxidation-reduction process
WL96_RS13110	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
WL96_RS13115	COG1737	Transcriptional regulator
WL96_RS13115	COG0837	glucose binding
WL96_RS13135	COG0477	Major facilitator Superfamily
WL96_RS13155	COG0235	Class ii aldolase
WL96_RS13160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WL96_RS13165	COG2186	Transcriptional regulator
WL96_RS13170	COG0247	lactate metabolic process
WL96_RS13180	COG1139	Iron-sulfur cluster binding protein
WL96_RS13185	COG1620	l-lactate permease
WL96_RS13190	COG0501	Belongs to the peptidase M48B family
WL96_RS13205	COG1028	Short-chain dehydrogenase reductase Sdr
WL96_RS13220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WL96_RS13245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WL96_RS13270	COG1028	Short-chain dehydrogenase reductase Sdr
WL96_RS13275	COG0183	Belongs to the thiolase family
WL96_RS13290	COG0629	single-stranded DNA binding
WL96_RS13295	COG2814	Major facilitator Superfamily
WL96_RS13320	COG1280	lysine exporter protein (LysE YggA)
WL96_RS13325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WL96_RS13340	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WL96_RS13355	COG1137	ATPase activity
WL96_RS13360	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WL96_RS13365	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WL96_RS13380	COG1660	Displays ATPase and GTPase activities
WL96_RS13390	COG1194	a g-specific adenine glycosylase
WL96_RS13395	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WL96_RS13405	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
WL96_RS13410	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WL96_RS13420	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WL96_RS13425	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
WL96_RS13440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WL96_RS13445	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WL96_RS13450	COG0742	ribosomal rna small subunit methyltransferase
WL96_RS13460	COG0625	glutathione transferase activity
WL96_RS13465	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WL96_RS13470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WL96_RS13485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WL96_RS13500	COG1294	oxidase, subunit
WL96_RS13515	COG2190	(PTS) system
WL96_RS13515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WL96_RS13515	COG1263	PTS System
WL96_RS13520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WL96_RS13520	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WL96_RS13525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WL96_RS13530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WL96_RS13535	COG2188	Transcriptional regulator
WL96_RS13540	COG0587	DNA-directed DNA polymerase activity
WL96_RS13560	COG0840	transmembrane signaling receptor activity
WL96_RS13570	COG1999	signal sequence binding
WL96_RS13575	COG0109	protoheme IX farnesyltransferase activity
WL96_RS13580	COG1612	heme a metabolic process
WL96_RS13615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WL96_RS13630	COG2226	methyltransferase
WL96_RS13635	COG1040	competence protein
WL96_RS13640	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
WL96_RS13645	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
WL96_RS13650	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WL96_RS13655	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WL96_RS13665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WL96_RS13670	COG0588	phosphoglycerate mutase activity
WL96_RS13675	COG0793	Belongs to the peptidase S41A family
WL96_RS13680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WL96_RS13685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WL96_RS13690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WL96_RS13700	COG0189	ligase activity
WL96_RS13710	COG0004	ammonium transporteR
WL96_RS13720	COG2960	long-chain fatty acid transporting porin activity
WL96_RS13730	COG2801	Transposase and inactivated derivatives
WL96_RS13735	COG2963	transposase activity
WL96_RS13795	COG0606	chelatase, subunit chli
WL96_RS13815	COG4191	Histidine kinase
WL96_RS13820	COG1301	dicarboxylic acid transport
WL96_RS13825	COG1960	acyl-CoA dehydrogenase activity
WL96_RS13830	COG1960	acyl-CoA dehydrogenase activity
WL96_RS13840	COG0583	DNA-binding transcription factor activity
WL96_RS13845	COG0405	Gamma-glutamyltransferase
WL96_RS13850	COG3318	Belongs to the UPF0149 family
WL96_RS13850	COG3012	SEC-C Motif Domain Protein
WL96_RS13855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WL96_RS13865	COG4521	taurine ABC transporter
WL96_RS13875	COG0321	lipoyl(octanoyl) transferase activity
WL96_RS13885	COG0583	DNA-binding transcription factor activity
WL96_RS13890	COG2921	Belongs to the UPF0250 family
WL96_RS13900	COG1686	Belongs to the peptidase S11 family
WL96_RS13930	COG1127	ABC transporter
WL96_RS13935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WL96_RS13940	COG0737	Belongs to the 5'-nucleotidase family
WL96_RS13950	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
WL96_RS13950	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
WL96_RS13955	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
WL96_RS13965	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WL96_RS13985	COG1024	Enoyl-CoA hydratase
WL96_RS14025	COG0018	arginyl-trna synthetase
WL96_RS14035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WL96_RS14040	COG0300	oxidoreductase activity
WL96_RS14045	COG0747	negative chemotaxis
WL96_RS14055	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
WL96_RS14060	COG0288	reversible hydration of carbon dioxide
WL96_RS14065	COG0300	oxidoreductase activity
WL96_RS14070	COG3012	SEC-C Motif Domain Protein
WL96_RS14085	COG0156	8-amino-7-oxononanoate synthase activity
WL96_RS14090	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WL96_RS14095	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WL96_RS14105	COG2199	diguanylate cyclase activity
WL96_RS14105	COG2200	EAL domain
WL96_RS14110	COG0025	NhaP-type Na H and K H
WL96_RS14120	COG0110	maltose O-acetyltransferase activity
WL96_RS14130	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WL96_RS14135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WL96_RS14140	COG0583	DNA-binding transcription factor activity
WL96_RS14150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WL96_RS14155	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WL96_RS14160	COG2080	2 iron, 2 sulfur cluster binding
WL96_RS14170	COG3511	phospholipase C
WL96_RS14185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WL96_RS14215	COG0596	Alpha beta hydrolase
WL96_RS14225	COG0583	DNA-binding transcription factor activity
WL96_RS14250	COG1609	Transcriptional regulator
WL96_RS14290	COG0037	tRNA processing
WL96_RS14295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WL96_RS14300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WL96_RS14330	COG1012	belongs to the aldehyde dehydrogenase family
WL96_RS14335	COG1917	Cupin 2, conserved barrel domain protein
WL96_RS14340	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WL96_RS14345	COG0174	glutamine synthetase
WL96_RS14360	COG3842	ATPase activity
WL96_RS14365	COG1176	ABC-type spermidine putrescine transport system, permease component I
WL96_RS14370	COG1177	transmembrane transport
WL96_RS14380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WL96_RS14385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WL96_RS14415	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WL96_RS14440	COG2233	PERMEase
WL96_RS14455	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
WL96_RS14465	COG1706	bacterial-type flagellum-dependent cell motility
WL96_RS14470	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WL96_RS14490	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
WL96_RS14495	COG1558	bacterial-type flagellum-dependent cell motility
WL96_RS14500	COG1815	bacterial-type flagellum-dependent cell motility
WL96_RS14510	COG2747	anti-sigma28 factor FlgM
WL96_RS14520	COG0006	proline dipeptidase activity
WL96_RS14530	COG0617	tRNA 3'-terminal CCA addition
WL96_RS14545	COG0741	lytic transglycosylase activity
WL96_RS14550	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WL96_RS14560	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WL96_RS14565	COG1984	allophanate hydrolase subunit 2
WL96_RS14570	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
WL96_RS14580	COG4608	Belongs to the ABC transporter superfamily
WL96_RS14585	COG0444	Belongs to the ABC transporter superfamily
WL96_RS14590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WL96_RS14595	COG0601	transmembrane transport
WL96_RS14600	COG0747	negative chemotaxis
WL96_RS14615	COG0579	oxidoreductase
WL96_RS14620	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WL96_RS14635	COG3568	Endonuclease Exonuclease Phosphatase
WL96_RS14650	COG2197	response regulator
WL96_RS14655	COG0531	amino acid
WL96_RS14675	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WL96_RS14695	COG1677	Flagellar hook-basal body complex protein FliE
WL96_RS14765	COG0667	Aldo Keto reductase
WL96_RS14785	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
WL96_RS14790	COG1560	Kdo2-lipid A biosynthetic process
WL96_RS14795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WL96_RS14805	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WL96_RS14810	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WL96_RS14815	COG0523	cobalamin synthesis protein
WL96_RS14825	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WL96_RS14830	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WL96_RS14835	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
WL96_RS14850	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WL96_RS14860	COG1309	transcriptional regulator
WL96_RS14870	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WL96_RS14875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WL96_RS14880	COG2814	Major facilitator Superfamily
WL96_RS14890	COG2207	Transcriptional regulator
WL96_RS14895	COG1064	alcohol dehydrogenase
WL96_RS14900	COG0708	Exodeoxyribonuclease III
WL96_RS14905	COG2326	polyphosphate kinase activity
WL96_RS14910	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WL96_RS14915	COG0154	amidase activity
WL96_RS14920	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WL96_RS14925	COG1077	Cell shape determining protein MreB Mrl
WL96_RS14940	COG0768	penicillin binding
WL96_RS14945	COG0772	Belongs to the SEDS family
WL96_RS14960	COG0720	synthase
WL96_RS14965	COG0602	queuosine metabolic process
WL96_RS14970	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WL96_RS14980	COG2204	response regulator
WL96_RS14985	COG5000	phosphorelay sensor kinase activity
WL96_RS15000	COG0501	Belongs to the peptidase M48B family
WL96_RS15010	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WL96_RS15015	COG0242	peptide deformylase activity
WL96_RS15020	COG0758	DNA mediated transformation
WL96_RS15035	COG0583	DNA-binding transcription factor activity
WL96_RS15040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WL96_RS15075	COG1620	l-lactate permease
WL96_RS15100	COG2169	Transcriptional regulator
WL96_RS15100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WL96_RS15120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WL96_RS15130	COG2203	Gaf domain
WL96_RS15130	COG4251	negative regulation of phosphorylation
WL96_RS15130	COG3706	GGDEF domain
WL96_RS15130	COG5001	Diguanylate cyclase
WL96_RS15135	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WL96_RS15145	COG0706	membrane insertase activity
WL96_RS15150	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
WL96_RS15165	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WL96_RS15510	COG0523	cobalamin synthesis protein
WL96_RS16170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WL96_RS16225	COG0318	PFAM AMP-dependent synthetase and ligase
WL96_RS16470	COG0210	DNA helicase
WL96_RS16725	COG0154	amidase activity
WL96_RS17045	COG0514	ATP-dependent DNA helicase (RecQ)
WL96_RS17235	COG0070	glutamate synthase
WL96_RS17235	COG0067	glutamate synthase
WL96_RS17235	COG0069	glutamate synthase activity
WL96_RS17240	COG0069	glutamate synthase activity
WL96_RS17240	COG0070	glutamate synthase
WL96_RS17240	COG0067	glutamate synthase
WL96_RS17280	COG0352	thiamine-phosphate diphosphorylase activity
WL96_RS17420	COG1401	restriction endodeoxyribonuclease activity
WL96_RS17750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WL96_RS18285	COG1301	dicarboxylic acid transport
WL96_RS18730	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WL96_RS19615	COG1674	ftsk spoiiie
WL96_RS19705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WL96_RS19870	COG3383	formate dehydrogenase (NAD+) activity
WL96_RS20085	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WL96_RS20150	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WL96_RS20355	COG0322	excinuclease ABC activity
WL96_RS20455	COG3511	phospholipase C
WL96_RS20660	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WL96_RS20675	COG1074	ATP-dependent DNA helicase activity
WL96_RS20945	COG0477	Major facilitator Superfamily
WL96_RS21065	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WL96_RS21365	COG0457	Tetratricopeptide repeat
WL96_RS21545	COG3962	Belongs to the TPP enzyme family
WL96_RS21760	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
WL96_RS21760	COG0644	oxidoreductase
WL96_RS21920	COG1566	PFAM secretion protein HlyD family protein
WL96_RS21980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WL96_RS22410	COG0419	ATPase involved in DNA repair
WL96_RS22715	COG2719	SpoVR family
WL96_RS22730	COG0477	Major facilitator Superfamily
WL96_RS22905	COG4774	siderophore transport
WL96_RS23445	COG0488	(ABC) transporter
WL96_RS23560	COG1199	ATP-dependent helicase activity
WL96_RS23580	COG3158	transport of potassium into the cell
WL96_RS23880	COG3960	tartronate-semialdehyde synthase activity
WL96_RS24070	COG0047	phosphoribosylformylglycinamidine synthase activity
WL96_RS24070	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WL96_RS24195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WL96_RS24380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WL96_RS24655	COG0444	Belongs to the ABC transporter superfamily
WL96_RS24760	COG0037	tRNA processing
WL96_RS25090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WL96_RS25675	COG0683	leucine binding
WL96_RS25725	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WL96_RS25725	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WL96_RS25800	COG0745	RESPONSE REGULATOR receiver
WL96_RS25815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WL96_RS26090	COG0281	malic enzyme
WL96_RS26090	COG0280	phosphate acetyltransferase
WL96_RS26965	COG3384	dioxygenase
WL96_RS26990	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WL96_RS27460	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WL96_RS27460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WL96_RS27515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WL96_RS27535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WL96_RS27865	COG0482	sulfurtransferase activity
WL96_RS27970	COG0793	Belongs to the peptidase S41A family
WL96_RS28185	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WL96_RS28190	COG0586	Pfam SNARE associated Golgi protein
WL96_RS28600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WL96_RS28660	COG1129	ABC transporter
WL96_RS28855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WL96_RS28855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WL96_RS28925	COG1674	ftsk spoiiie
WL96_RS29020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WL96_RS29440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WL96_RS29445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WL96_RS29545	COG0481	GTPase activity
WL96_RS29830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WL96_RS29905	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WL96_RS29920	COG1074	ATP-dependent DNA helicase activity