A4V04_RS07195 c271dad1146f275a0d461cc0ccb45e54 450 Pfam PF01523 Putative modulator of DNA gyrase 35 323 4.7E-53 T 26-04-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A4V04_RS07195 c271dad1146f275a0d461cc0ccb45e54 450 SUPERFAMILY SSF111283 12 450 1.7E-118 T 26-04-2017 A4V04_RS03690 6c7932228d17ec08735704e2c7927f79 590 Gene3D G3DSA:3.40.190.10 112 237 4.0E-5 T 26-04-2017 A4V04_RS03690 6c7932228d17ec08735704e2c7927f79 590 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 44 289 4.6E-21 T 26-04-2017 A4V04_RS03690 6c7932228d17ec08735704e2c7927f79 590 SUPERFAMILY SSF53850 67 274 3.41E-12 T 26-04-2017 A4V04_RS03690 6c7932228d17ec08735704e2c7927f79 590 SUPERFAMILY SSF47384 356 432 2.75E-7 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS03690 6c7932228d17ec08735704e2c7927f79 590 SUPERFAMILY SSF55874 430 584 1.31E-22 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS03690 6c7932228d17ec08735704e2c7927f79 590 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 478 579 3.4E-11 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS03690 6c7932228d17ec08735704e2c7927f79 590 Gene3D G3DSA:3.30.565.10 408 585 1.8E-24 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS03690 6c7932228d17ec08735704e2c7927f79 590 SMART SM00387 473 582 8.6E-16 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS03690 6c7932228d17ec08735704e2c7927f79 590 SMART SM00388 363 433 7.0E-4 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS09090 0e69beeeb73b54130fdea37db1403682 447 Gene3D G3DSA:3.80.30.20 64 274 1.2E-20 T 26-04-2017 IPR023404 Radical SAM, alpha/beta horseshoe A4V04_RS09090 0e69beeeb73b54130fdea37db1403682 447 Pfam PF04055 Radical SAM superfamily 69 225 6.4E-14 T 26-04-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 A4V04_RS09090 0e69beeeb73b54130fdea37db1403682 447 SMART SM00729 63 274 1.4E-23 T 26-04-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4V04_RS09090 0e69beeeb73b54130fdea37db1403682 447 SUPERFAMILY SSF102114 51 428 9.94E-64 T 26-04-2017 A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 Hamap MF_00006 Argininosuccinate lyase [argH]. 7 470 29.613 T 26-04-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 Gene3D G3DSA:1.10.40.30 383 446 2.9E-14 T 26-04-2017 A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 Pfam PF14698 Argininosuccinate lyase C-terminal 371 446 5.7E-15 T 26-04-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 PRINTS PR00149 Fumarate lyase superfamily signature 154 172 4.3E-17 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 PRINTS PR00149 Fumarate lyase superfamily signature 109 127 4.3E-17 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 PRINTS PR00149 Fumarate lyase superfamily signature 282 298 4.3E-17 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 PRINTS PR00149 Fumarate lyase superfamily signature 238 265 4.3E-17 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 PRINTS PR00145 Argininosuccinate lyase family signature 282 298 1.3E-27 T 26-04-2017 A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 PRINTS PR00145 Argininosuccinate lyase family signature 149 169 1.3E-27 T 26-04-2017 A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 PRINTS PR00145 Argininosuccinate lyase family signature 200 216 1.3E-27 T 26-04-2017 A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 PRINTS PR00145 Argininosuccinate lyase family signature 238 262 1.3E-27 T 26-04-2017 A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 PRINTS PR00145 Argininosuccinate lyase family signature 108 130 1.3E-27 T 26-04-2017 A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 Gene3D G3DSA:1.10.275.10 43 113 4.8E-11 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 Pfam PF00206 Lyase 52 304 7.1E-43 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 TIGRFAM TIGR00838 argH: argininosuccinate lyase 42 471 2.6E-112 T 26-04-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 Gene3D G3DSA:1.20.200.10 114 382 2.5E-63 T 26-04-2017 A4V04_RS01650 72fba80a7d166ea98f8e983b253cbb84 503 SUPERFAMILY SSF48557 37 472 8.01E-97 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS02485 8f40bb882ba352f5bd9fb90f48ddf497 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 3.1E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS02485 8f40bb882ba352f5bd9fb90f48ddf497 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 3.1E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS02485 8f40bb882ba352f5bd9fb90f48ddf497 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 3.1E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS02485 8f40bb882ba352f5bd9fb90f48ddf497 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 67 1.7E-19 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS02485 8f40bb882ba352f5bd9fb90f48ddf497 322 SUPERFAMILY SSF46785 9 105 1.82E-21 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02485 8f40bb882ba352f5bd9fb90f48ddf497 322 Gene3D G3DSA:3.40.190.10 202 266 5.0E-9 T 26-04-2017 A4V04_RS02485 8f40bb882ba352f5bd9fb90f48ddf497 322 Pfam PF03466 LysR substrate binding domain 97 288 2.8E-16 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS02485 8f40bb882ba352f5bd9fb90f48ddf497 322 Gene3D G3DSA:3.40.190.10 124 201 2.6E-4 T 26-04-2017 A4V04_RS02485 8f40bb882ba352f5bd9fb90f48ddf497 322 Gene3D G3DSA:1.10.10.10 11 88 1.7E-24 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02485 8f40bb882ba352f5bd9fb90f48ddf497 322 SUPERFAMILY SSF53850 124 296 3.26E-15 T 26-04-2017 A4V04_RS00975 f3a53a4baa994cb683637aef160e8c6f 163 SUPERFAMILY SSF52540 35 135 3.24E-18 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00975 f3a53a4baa994cb683637aef160e8c6f 163 Gene3D G3DSA:3.40.50.300 8 162 1.2E-41 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00975 f3a53a4baa994cb683637aef160e8c6f 163 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 149 7.2E-34 T 26-04-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A4V04_RS00975 f3a53a4baa994cb683637aef160e8c6f 163 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 10 139 6.3E-34 T 26-04-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A4V04_RS11865 2c04cd4537cf06ff362916887fa8efed 167 TIGRFAM TIGR04108 HutX: putative heme utilization carrier protein HutX 11 162 2.6E-41 T 26-04-2017 IPR010413 Heme utilization carrier protein HutX-like A4V04_RS11865 2c04cd4537cf06ff362916887fa8efed 167 SUPERFAMILY SSF144064 6 163 1.83E-28 T 26-04-2017 A4V04_RS11865 2c04cd4537cf06ff362916887fa8efed 167 Gene3D G3DSA:3.40.1570.10 3 166 1.9E-50 T 26-04-2017 A4V04_RS11865 2c04cd4537cf06ff362916887fa8efed 167 Pfam PF06228 Haem utilisation ChuX/HutX 26 162 1.6E-24 T 26-04-2017 IPR010413 Heme utilization carrier protein HutX-like A4V04_RS09360 178ac48f3d29cf61ee16c61b468fcee0 422 Pfam PF03606 C4-dicarboxylate anaerobic carrier 59 421 1.9E-19 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS09360 178ac48f3d29cf61ee16c61b468fcee0 422 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 58 413 1.1E-59 T 26-04-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 2.7E-11 T 26-04-2017 IPR004176 Clp, N-terminal GO:0019538 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 96 145 8.3E-7 T 26-04-2017 IPR004176 Clp, N-terminal GO:0019538 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 635 653 - T 26-04-2017 IPR028299 ClpA/B, conserved site 2 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 SMART SM01086 769 858 3.3E-33 T 26-04-2017 IPR019489 Clp ATPase, C-terminal A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 Gene3D G3DSA:1.10.8.60 343 428 7.0E-38 T 26-04-2017 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 SUPERFAMILY SSF52540 159 548 5.43E-99 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 Gene3D G3DSA:1.10.8.60 781 859 2.7E-27 T 26-04-2017 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 337 3.7E-14 T 26-04-2017 IPR003959 ATPase, AAA-type, core GO:0005524 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 Gene3D G3DSA:3.40.50.300 554 780 6.0E-57 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 Gene3D G3DSA:3.40.50.300 159 342 2.7E-52 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 SUPERFAMILY SSF81923 4 156 2.22E-37 T 26-04-2017 IPR004176 Clp, N-terminal GO:0019538 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 Gene3D G3DSA:1.10.1780.10 1 148 4.0E-39 T 26-04-2017 IPR004176 Clp, N-terminal GO:0019538 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 Pfam PF07724 AAA domain (Cdc48 subfamily) 600 763 8.7E-57 T 26-04-2017 IPR003959 ATPase, AAA-type, core GO:0005524 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 SUPERFAMILY SSF52540 550 858 1.11E-80 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 605 623 3.8E-42 T 26-04-2017 IPR001270 ClpA/B family GO:0005524 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 679 697 3.8E-42 T 26-04-2017 IPR001270 ClpA/B family GO:0005524 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 668 3.8E-42 T 26-04-2017 IPR001270 ClpA/B family GO:0005524 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 712 726 3.8E-42 T 26-04-2017 IPR001270 ClpA/B family GO:0005524 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 769 849 2.4E-23 T 26-04-2017 IPR019489 Clp ATPase, C-terminal A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 858 0.0 T 26-04-2017 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 SMART SM00382 601 770 7.1E-10 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 SMART SM00382 198 343 1.4E-11 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS00345 ab4699413d240bb2817aa5af8d3dc21b 863 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 26-04-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 A4V04_RS03575 b04eefe74b323fda252545e8ffd19c65 273 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 7 247 2.5E-60 T 26-04-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 A4V04_RS03575 b04eefe74b323fda252545e8ffd19c65 273 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 7 23 2.8E-16 T 26-04-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 A4V04_RS03575 b04eefe74b323fda252545e8ffd19c65 273 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 29 43 2.8E-16 T 26-04-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 A4V04_RS03575 b04eefe74b323fda252545e8ffd19c65 273 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 179 191 2.8E-16 T 26-04-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 A4V04_RS03575 b04eefe74b323fda252545e8ffd19c65 273 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 48 61 2.8E-16 T 26-04-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 A4V04_RS03575 b04eefe74b323fda252545e8ffd19c65 273 SUPERFAMILY SSF53335 1 272 1.55E-71 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS03575 b04eefe74b323fda252545e8ffd19c65 273 TIGRFAM TIGR00571 dam: DNA adenine methylase 1 269 8.0E-83 T 26-04-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 A4V04_RS03575 b04eefe74b323fda252545e8ffd19c65 273 PIRSF PIRSF000398 1 273 2.3E-67 T 26-04-2017 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 A4V04_RS03575 b04eefe74b323fda252545e8ffd19c65 273 Gene3D G3DSA:1.10.1020.10 58 157 1.7E-27 T 26-04-2017 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 A4V04_RS03575 b04eefe74b323fda252545e8ffd19c65 273 Gene3D G3DSA:3.40.50.150 1 57 1.1E-54 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS03575 b04eefe74b323fda252545e8ffd19c65 273 Gene3D G3DSA:3.40.50.150 164 273 1.1E-54 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS00085 fd568ece751e4e4a956954dec13353b3 457 Gene3D G3DSA:3.20.70.20 1 457 8.8E-189 T 26-04-2017 A4V04_RS00085 fd568ece751e4e4a956954dec13353b3 457 SUPERFAMILY SSF51998 4 452 1.1E-158 T 26-04-2017 A4V04_RS00085 fd568ece751e4e4a956954dec13353b3 457 Pfam PF05167 Uncharacterised ACR (DUF711) 13 421 1.9E-164 T 26-04-2017 IPR007841 Uncharacterised protein family UPF0210 A4V04_RS11670 00997da71bc2131572c38ec9e4deae1c 86 Gene3D G3DSA:2.40.50.100 20 84 7.0E-28 T 26-04-2017 A4V04_RS11670 00997da71bc2131572c38ec9e4deae1c 86 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 29 74 1.0E-12 T 26-04-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11670 00997da71bc2131572c38ec9e4deae1c 86 PRINTS PR00063 Ribosomal protein L27 signature 54 78 5.4E-35 T 26-04-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11670 00997da71bc2131572c38ec9e4deae1c 86 PRINTS PR00063 Ribosomal protein L27 signature 4 28 5.4E-35 T 26-04-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11670 00997da71bc2131572c38ec9e4deae1c 86 PRINTS PR00063 Ribosomal protein L27 signature 29 53 5.4E-35 T 26-04-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11670 00997da71bc2131572c38ec9e4deae1c 86 Pfam PF01016 Ribosomal L27 protein 2 82 4.1E-36 T 26-04-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11670 00997da71bc2131572c38ec9e4deae1c 86 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 26-04-2017 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11670 00997da71bc2131572c38ec9e4deae1c 86 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 27.543 T 26-04-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11670 00997da71bc2131572c38ec9e4deae1c 86 SUPERFAMILY SSF110324 2 82 1.4E-31 T 26-04-2017 A4V04_RS11670 00997da71bc2131572c38ec9e4deae1c 86 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 2.2E-38 T 26-04-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS10600 eac5622aa3d510c25027876e42d35ba3 362 SUPERFAMILY SSF52540 7 247 9.64E-85 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10600 eac5622aa3d510c25027876e42d35ba3 362 Gene3D G3DSA:3.40.50.300 3 239 1.7E-76 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10600 eac5622aa3d510c25027876e42d35ba3 362 Pfam PF00005 ABC transporter 25 166 9.2E-33 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS10600 eac5622aa3d510c25027876e42d35ba3 362 SUPERFAMILY SSF50331 242 324 2.55E-7 T 26-04-2017 IPR008995 Molybdate/tungstate binding, C-terminal A4V04_RS10600 eac5622aa3d510c25027876e42d35ba3 362 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS10600 eac5622aa3d510c25027876e42d35ba3 362 SMART SM00382 33 216 1.4E-17 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS00895 78d3b41368750f8e43d3cd9a6b788a51 192 SUPERFAMILY SSF52218 93 146 4.33E-16 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS00895 78d3b41368750f8e43d3cd9a6b788a51 192 SUPERFAMILY SSF52218 22 59 4.33E-16 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS00895 78d3b41368750f8e43d3cd9a6b788a51 192 Pfam PF12682 Flavodoxin 22 185 1.2E-16 T 26-04-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A4V04_RS00895 78d3b41368750f8e43d3cd9a6b788a51 192 Gene3D G3DSA:3.40.50.360 89 145 1.2E-16 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS00895 78d3b41368750f8e43d3cd9a6b788a51 192 Gene3D G3DSA:3.40.50.360 21 54 1.2E-16 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS07630 5b64b0bcf28fe9df0626bdaf8c154a7a 278 Gene3D G3DSA:1.10.530.10 123 235 1.4E-19 T 26-04-2017 A4V04_RS07630 5b64b0bcf28fe9df0626bdaf8c154a7a 278 Pfam PF01464 Transglycosylase SLT domain 122 216 1.5E-13 T 26-04-2017 IPR008258 Transglycosylase SLT domain 1 A4V04_RS07630 5b64b0bcf28fe9df0626bdaf8c154a7a 278 SUPERFAMILY SSF53955 123 236 9.7E-19 T 26-04-2017 IPR023346 Lysozyme-like domain A4V04_RS02870 a5abc532943d6b29054c4e61f15fffff 62 Pfam PF01783 Ribosomal L32p protein family 2 55 1.7E-15 T 26-04-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS02870 a5abc532943d6b29054c4e61f15fffff 62 SUPERFAMILY SSF57829 2 54 4.15E-15 T 26-04-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 A4V04_RS02870 a5abc532943d6b29054c4e61f15fffff 62 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 2.5E-17 T 26-04-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS02870 a5abc532943d6b29054c4e61f15fffff 62 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 15.389 T 26-04-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS05215 a3674ea76f24b46277bde685493a09cf 96 Gene3D G3DSA:3.30.70.240 4 69 2.1E-16 T 26-04-2017 IPR000640 Translation elongation factor EFG, V domain A4V04_RS05215 a3674ea76f24b46277bde685493a09cf 96 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 5 62 4.4E-9 T 26-04-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 A4V04_RS05215 a3674ea76f24b46277bde685493a09cf 96 Pfam PF09827 CRISPR associated protein Cas2 5 68 1.3E-11 T 26-04-2017 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 A4V04_RS05215 a3674ea76f24b46277bde685493a09cf 96 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 3 88 12.012 T 26-04-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 A4V04_RS05215 a3674ea76f24b46277bde685493a09cf 96 SUPERFAMILY SSF143430 4 70 9.55E-15 T 26-04-2017 A4V04_RS06865 421467c03f69a4a080c506bc0ae32234 349 PIRSF PIRSF005644 14 349 6.3E-128 T 26-04-2017 IPR011854 Hydrogenase expression/formation protein HypE A4V04_RS06865 421467c03f69a4a080c506bc0ae32234 349 SUPERFAMILY SSF55326 23 167 4.01E-34 T 26-04-2017 A4V04_RS06865 421467c03f69a4a080c506bc0ae32234 349 SUPERFAMILY SSF56042 170 345 3.74E-44 T 26-04-2017 IPR010918 AIR synthase-related protein, C-terminal domain A4V04_RS06865 421467c03f69a4a080c506bc0ae32234 349 Pfam PF00586 AIR synthase related protein, N-terminal domain 51 163 4.8E-17 T 26-04-2017 IPR016188 PurM-like, N-terminal domain A4V04_RS06865 421467c03f69a4a080c506bc0ae32234 349 Pfam PF02769 AIR synthase related protein, C-terminal domain 175 325 1.5E-26 T 26-04-2017 IPR010918 AIR synthase-related protein, C-terminal domain A4V04_RS06865 421467c03f69a4a080c506bc0ae32234 349 Gene3D G3DSA:3.30.1330.10 35 165 2.1E-25 T 26-04-2017 IPR016188 PurM-like, N-terminal domain A4V04_RS06865 421467c03f69a4a080c506bc0ae32234 349 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 18 349 1.3E-142 T 26-04-2017 IPR011854 Hydrogenase expression/formation protein HypE A4V04_RS06865 421467c03f69a4a080c506bc0ae32234 349 Gene3D G3DSA:3.90.650.10 173 327 5.3E-28 T 26-04-2017 IPR010918 AIR synthase-related protein, C-terminal domain A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 Gene3D G3DSA:3.40.50.970 239 328 7.7E-74 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 Gene3D G3DSA:3.40.50.970 19 197 7.7E-74 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 ProSitePatterns PS00802 Transketolase signature 2. 420 436 - T 26-04-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 SUPERFAMILY SSF52518 291 476 6.73E-63 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 Gene3D G3DSA:3.40.50.920 491 619 3.6E-33 T 26-04-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 7 619 1.2E-253 T 26-04-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 5 279 3.5E-114 T 26-04-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 4 620 45.112 T 26-04-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 ProSitePatterns PS00801 Transketolase signature 1. 30 49 - T 26-04-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 Pfam PF02779 Transketolase, pyrimidine binding domain 315 474 7.7E-42 T 26-04-2017 IPR005475 Transketolase-like, pyrimidine-binding domain A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 Gene3D G3DSA:3.40.50.970 329 490 5.7E-42 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 SUPERFAMILY SSF52922 486 619 3.53E-30 T 26-04-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 SMART SM00861 314 478 2.6E-73 T 26-04-2017 IPR005475 Transketolase-like, pyrimidine-binding domain A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 SUPERFAMILY SSF52518 2 344 1.61E-75 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS05340 1ee6991d1760178c3e134bc52553798f 621 Pfam PF02780 Transketolase, C-terminal domain 502 611 1.7E-24 T 26-04-2017 IPR033248 Transketolase, C-terminal domain A4V04_RS00045 720f62ee4132ab16c64f810ae3e4cdec 255 Gene3D G3DSA:3.40.50.720 5 237 9.9E-46 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS00045 720f62ee4132ab16c64f810ae3e4cdec 255 Pfam PF00106 short chain dehydrogenase 5 199 8.8E-35 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS00045 720f62ee4132ab16c64f810ae3e4cdec 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.8E-12 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS00045 720f62ee4132ab16c64f810ae3e4cdec 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.8E-12 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS00045 720f62ee4132ab16c64f810ae3e4cdec 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.8E-12 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS00045 720f62ee4132ab16c64f810ae3e4cdec 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.8E-12 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS00045 720f62ee4132ab16c64f810ae3e4cdec 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 26-04-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4V04_RS00045 720f62ee4132ab16c64f810ae3e4cdec 255 SUPERFAMILY SSF51735 6 239 3.38E-39 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS12190 eeb73708eeb308e488efc86d43fea324 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-6 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS12190 eeb73708eeb308e488efc86d43fea324 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-6 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS12190 eeb73708eeb308e488efc86d43fea324 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-6 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS12190 eeb73708eeb308e488efc86d43fea324 320 Gene3D G3DSA:3.40.190.10 87 228 4.5E-15 T 26-04-2017 A4V04_RS12190 eeb73708eeb308e488efc86d43fea324 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 7.7E-15 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS12190 eeb73708eeb308e488efc86d43fea324 320 SUPERFAMILY SSF53850 87 296 1.71E-23 T 26-04-2017 A4V04_RS12190 eeb73708eeb308e488efc86d43fea324 320 Pfam PF03466 LysR substrate binding domain 87 293 1.6E-19 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS12190 eeb73708eeb308e488efc86d43fea324 320 Gene3D G3DSA:1.10.10.10 1 79 1.4E-20 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS12190 eeb73708eeb308e488efc86d43fea324 320 SUPERFAMILY SSF46785 1 78 1.58E-18 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS00955 5f934446a0a369402c03bbdc7fc6dded 287 Pfam PF07885 Ion channel 147 222 2.4E-7 T 26-04-2017 IPR013099 Potassium channel domain A4V04_RS00955 5f934446a0a369402c03bbdc7fc6dded 287 SUPERFAMILY SSF81324 20 223 1.03E-22 T 26-04-2017 A4V04_RS00955 5f934446a0a369402c03bbdc7fc6dded 287 Gene3D G3DSA:1.10.287.70 18 223 4.7E-23 T 26-04-2017 A4V04_RS09805 501366933ad49bb780a976f96734ec65 348 Gene3D G3DSA:3.30.420.40 10 165 7.5E-43 T 26-04-2017 A4V04_RS09805 501366933ad49bb780a976f96734ec65 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 3.5E-60 T 26-04-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4V04_RS09805 501366933ad49bb780a976f96734ec65 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 53 71 3.5E-60 T 26-04-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4V04_RS09805 501366933ad49bb780a976f96734ec65 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 192 212 3.5E-60 T 26-04-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4V04_RS09805 501366933ad49bb780a976f96734ec65 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 137 156 3.5E-60 T 26-04-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4V04_RS09805 501366933ad49bb780a976f96734ec65 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 73 96 3.5E-60 T 26-04-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4V04_RS09805 501366933ad49bb780a976f96734ec65 348 Gene3D G3DSA:3.30.420.40 268 322 8.7E-32 T 26-04-2017 A4V04_RS09805 501366933ad49bb780a976f96734ec65 348 Gene3D G3DSA:3.30.420.40 166 191 8.7E-32 T 26-04-2017 A4V04_RS09805 501366933ad49bb780a976f96734ec65 348 SUPERFAMILY SSF53067 155 334 1.03E-46 T 26-04-2017 A4V04_RS09805 501366933ad49bb780a976f96734ec65 348 SUPERFAMILY SSF53067 9 153 2.78E-36 T 26-04-2017 A4V04_RS09805 501366933ad49bb780a976f96734ec65 348 Gene3D G3DSA:3.90.640.10 192 264 1.3E-28 T 26-04-2017 A4V04_RS09805 501366933ad49bb780a976f96734ec65 348 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 340 3.5E-151 T 26-04-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4V04_RS09805 501366933ad49bb780a976f96734ec65 348 Pfam PF06723 MreB/Mbl protein 10 340 2.0E-143 T 26-04-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4V04_RS02700 d49841fb76733619aa7d52d85e350b59 257 SMART SM00479 2 175 2.0E-48 T 26-04-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III A4V04_RS02700 d49841fb76733619aa7d52d85e350b59 257 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 219 2.0E-72 T 26-04-2017 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS02700 d49841fb76733619aa7d52d85e350b59 257 Gene3D G3DSA:3.30.420.10 2 178 7.3E-62 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS02700 d49841fb76733619aa7d52d85e350b59 257 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 2 208 4.8E-51 T 26-04-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS02700 d49841fb76733619aa7d52d85e350b59 257 Pfam PF00929 Exonuclease 4 166 2.0E-36 T 26-04-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III A4V04_RS02700 d49841fb76733619aa7d52d85e350b59 257 SUPERFAMILY SSF53098 3 176 1.69E-52 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS01770 63810e66a62c3429ea6b6567402df190 787 Pfam PF06986 Type-1V conjugative transfer system mating pair stabilisation 379 539 1.5E-24 T 26-04-2017 IPR014121 Type-F conjugative transfer system mating-pair stabilisation protein TraN A4V04_RS01770 63810e66a62c3429ea6b6567402df190 787 Pfam PF06986 Type-1V conjugative transfer system mating pair stabilisation 265 349 2.5E-13 T 26-04-2017 IPR014121 Type-F conjugative transfer system mating-pair stabilisation protein TraN A4V04_RS01770 63810e66a62c3429ea6b6567402df190 787 Pfam PF06986 Type-1V conjugative transfer system mating pair stabilisation 38 126 8.9E-13 T 26-04-2017 IPR014121 Type-F conjugative transfer system mating-pair stabilisation protein TraN A4V04_RS01770 63810e66a62c3429ea6b6567402df190 787 Pfam PF06986 Type-1V conjugative transfer system mating pair stabilisation 152 232 5.8E-16 T 26-04-2017 IPR014121 Type-F conjugative transfer system mating-pair stabilisation protein TraN A4V04_RS01770 63810e66a62c3429ea6b6567402df190 787 Pfam PF06986 Type-1V conjugative transfer system mating pair stabilisation 629 710 8.3E-28 T 26-04-2017 IPR014121 Type-F conjugative transfer system mating-pair stabilisation protein TraN A4V04_RS11040 d13d67aef969f69502f545d43540b07e 532 Gene3D G3DSA:3.30.70.20 452 480 2.9E-68 T 26-04-2017 A4V04_RS11040 d13d67aef969f69502f545d43540b07e 532 Gene3D G3DSA:3.30.70.20 235 357 2.9E-68 T 26-04-2017 A4V04_RS11040 d13d67aef969f69502f545d43540b07e 532 Gene3D G3DSA:3.30.70.20 156 194 6.3E-11 T 26-04-2017 A4V04_RS11040 d13d67aef969f69502f545d43540b07e 532 SUPERFAMILY SSF54862 1 488 7.64E-149 T 26-04-2017 A4V04_RS11040 d13d67aef969f69502f545d43540b07e 532 Gene3D G3DSA:1.10.3650.10 358 418 3.2E-21 T 26-04-2017 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 A4V04_RS11040 d13d67aef969f69502f545d43540b07e 532 Gene3D G3DSA:3.30.70.20 195 234 6.9E-24 T 26-04-2017 A4V04_RS11040 d13d67aef969f69502f545d43540b07e 532 Gene3D G3DSA:3.30.70.20 5 58 2.1E-11 T 26-04-2017 A4V04_RS11040 d13d67aef969f69502f545d43540b07e 532 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 357 418 2.1E-18 T 26-04-2017 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 A4V04_RS11040 d13d67aef969f69502f545d43540b07e 532 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 499 2.3E-236 T 26-04-2017 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 A4V04_RS11040 d13d67aef969f69502f545d43540b07e 532 Pfam PF13247 4Fe-4S dicluster domain 175 270 8.3E-38 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS10050 c97efee8f7d63aad3b75dc0fcfbaa26c 187 SUPERFAMILY SSF52833 1 186 3.33E-58 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS10050 c97efee8f7d63aad3b75dc0fcfbaa26c 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 178 5.2E-6 T 26-04-2017 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4V04_RS10050 c97efee8f7d63aad3b75dc0fcfbaa26c 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 5.2E-99 T 26-04-2017 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4V04_RS10050 c97efee8f7d63aad3b75dc0fcfbaa26c 187 Gene3D G3DSA:3.40.30.10 4 183 7.7E-63 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS10050 c97efee8f7d63aad3b75dc0fcfbaa26c 187 Pfam PF00578 AhpC/TSA family 4 132 5.8E-35 T 26-04-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4V04_RS10050 c97efee8f7d63aad3b75dc0fcfbaa26c 187 PIRSF PIRSF000239 1 187 2.4E-56 T 26-04-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 125 408 4.2E-35 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 SUPERFAMILY SSF46548 406 540 5.75E-18 T 26-04-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 Pfam PF00037 4Fe-4S binding domain 513 535 2.4E-5 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 127 146 5.4E-18 T 26-04-2017 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 346 362 5.4E-18 T 26-04-2017 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 373 395 5.4E-18 T 26-04-2017 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 273 5.4E-18 T 26-04-2017 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 Gene3D G3DSA:3.50.50.60 346 428 3.1E-13 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 Gene3D G3DSA:3.50.50.60 191 211 3.1E-13 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 Gene3D G3DSA:3.50.50.60 212 345 3.3E-35 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 520 531 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 Gene3D G3DSA:1.10.1060.10 34 127 3.2E-24 T 26-04-2017 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 Gene3D G3DSA:1.10.1060.10 438 539 2.7E-19 T 26-04-2017 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 34 113 1.4E-16 T 26-04-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 488 499 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 148 5.8E-12 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 251 275 5.8E-12 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 383 401 5.8E-12 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 SUPERFAMILY SSF51971 124 355 4.47E-53 T 26-04-2017 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 SUPERFAMILY SSF46548 33 135 5.75E-21 T 26-04-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 A4V04_RS03705 00c6866acd3f7fe94fe860dc499754ae 542 Gene3D G3DSA:3.50.50.60 128 190 5.7E-17 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12595 88dbd5f9d2f0f46eafe2dea8318c6b00 251 SUPERFAMILY SSF51366 1 241 1.01E-72 T 26-04-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A4V04_RS12595 88dbd5f9d2f0f46eafe2dea8318c6b00 251 Pfam PF00977 Histidine biosynthesis protein 3 233 4.7E-74 T 26-04-2017 IPR006062 Histidine biosynthesis GO:0000105 A4V04_RS12595 88dbd5f9d2f0f46eafe2dea8318c6b00 251 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 241 35.569 T 26-04-2017 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A4V04_RS12595 88dbd5f9d2f0f46eafe2dea8318c6b00 251 Gene3D G3DSA:3.20.20.70 1 242 2.1E-82 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS12595 88dbd5f9d2f0f46eafe2dea8318c6b00 251 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 238 3.1E-76 T 26-04-2017 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A4V04_RS11315 6852b7aaba64895bfaa53e18ff5a7361 59 Pfam PF00327 Ribosomal protein L30p/L7e 6 56 1.3E-18 T 26-04-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A4V04_RS11315 6852b7aaba64895bfaa53e18ff5a7361 59 PIRSF PIRSF002211 1 59 2.6E-26 T 26-04-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 A4V04_RS11315 6852b7aaba64895bfaa53e18ff5a7361 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 6 57 7.3E-26 T 26-04-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 A4V04_RS11315 6852b7aaba64895bfaa53e18ff5a7361 59 Gene3D G3DSA:3.30.1390.20 3 59 2.1E-29 T 26-04-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A4V04_RS11315 6852b7aaba64895bfaa53e18ff5a7361 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 3 59 17.6 T 26-04-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 A4V04_RS11315 6852b7aaba64895bfaa53e18ff5a7361 59 ProSitePatterns PS00634 Ribosomal protein L30 signature. 24 56 - T 26-04-2017 IPR018038 Ribosomal protein L30, conserved site A4V04_RS11315 6852b7aaba64895bfaa53e18ff5a7361 59 SUPERFAMILY SSF55129 4 58 9.68E-20 T 26-04-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A4V04_RS10740 cb1386fa2246e7eae57e309172569fc4 311 Gene3D G3DSA:3.40.190.10 94 175 3.2E-4 T 26-04-2017 A4V04_RS10740 cb1386fa2246e7eae57e309172569fc4 311 SUPERFAMILY SSF46785 10 107 1.41E-15 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10740 cb1386fa2246e7eae57e309172569fc4 311 Gene3D G3DSA:1.10.10.10 9 83 5.2E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10740 cb1386fa2246e7eae57e309172569fc4 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 4.0E-15 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10740 cb1386fa2246e7eae57e309172569fc4 311 Gene3D G3DSA:3.40.190.10 176 257 2.5E-12 T 26-04-2017 A4V04_RS10740 cb1386fa2246e7eae57e309172569fc4 311 SUPERFAMILY SSF53850 92 292 8.87E-20 T 26-04-2017 A4V04_RS10740 cb1386fa2246e7eae57e309172569fc4 311 Pfam PF03466 LysR substrate binding domain 90 289 1.3E-15 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 Gene3D G3DSA:3.30.250.10 284 342 5.7E-24 T 26-04-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 SUPERFAMILY SSF52540 22 283 5.85E-63 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 SMART SM00382 73 244 3.9E-10 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 20 339 6.4E-162 T 26-04-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 Pfam PF00154 recA bacterial DNA recombination protein 22 284 6.9E-136 T 26-04-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 ProSitePatterns PS00321 recA signature. 229 237 - T 26-04-2017 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 Hamap MF_00268 Protein RecA [recA]. 20 345 49.193 T 26-04-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 SUPERFAMILY SSF54752 284 341 8.63E-18 T 26-04-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 Gene3D G3DSA:3.40.50.300 49 283 1.1E-79 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 PRINTS PR00142 RecA protein signature 143 172 1.1E-80 T 26-04-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 PRINTS PR00142 RecA protein signature 226 254 1.1E-80 T 26-04-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 PRINTS PR00142 RecA protein signature 313 330 1.1E-80 T 26-04-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 PRINTS PR00142 RecA protein signature 259 288 1.1E-80 T 26-04-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 PRINTS PR00142 RecA protein signature 109 138 1.1E-80 T 26-04-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4V04_RS12420 bb3ed7ef94ce8daea34143e48f7afc4b 368 PRINTS PR00142 RecA protein signature 181 210 1.1E-80 T 26-04-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4V04_RS12755 b3b1de60415d9110d0e5110a8a03846e 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 5.1E-15 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS12755 b3b1de60415d9110d0e5110a8a03846e 298 Gene3D G3DSA:1.10.10.10 9 93 6.0E-20 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS12755 b3b1de60415d9110d0e5110a8a03846e 298 Gene3D G3DSA:3.40.190.10 183 275 7.9E-19 T 26-04-2017 A4V04_RS12755 b3b1de60415d9110d0e5110a8a03846e 298 Pfam PF03466 LysR substrate binding domain 96 284 1.5E-24 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS12755 b3b1de60415d9110d0e5110a8a03846e 298 SUPERFAMILY SSF53850 90 295 5.25E-23 T 26-04-2017 A4V04_RS12755 b3b1de60415d9110d0e5110a8a03846e 298 Gene3D G3DSA:3.40.190.10 98 182 2.7E-12 T 26-04-2017 A4V04_RS12755 b3b1de60415d9110d0e5110a8a03846e 298 SUPERFAMILY SSF46785 9 115 5.45E-18 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS00230 dac67cad29b73c42e12728f55a539180 484 SUPERFAMILY SSF50249 9 66 1.83E-10 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS00230 dac67cad29b73c42e12728f55a539180 484 Gene3D G3DSA:2.40.50.140 4 78 1.5E-22 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS00230 dac67cad29b73c42e12728f55a539180 484 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 378 410 - T 26-04-2017 IPR030390 RNA methyltransferase TrmA, active site A4V04_RS00230 dac67cad29b73c42e12728f55a539180 484 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 432 442 - T 26-04-2017 IPR030391 RNA methyltransferase TrmA, conserved site A4V04_RS00230 dac67cad29b73c42e12728f55a539180 484 Gene3D G3DSA:3.40.50.150 258 448 6.9E-46 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS00230 dac67cad29b73c42e12728f55a539180 484 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 11 450 59.88 T 26-04-2017 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 A4V04_RS00230 dac67cad29b73c42e12728f55a539180 484 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 17 442 8.5E-86 T 26-04-2017 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 A4V04_RS00230 dac67cad29b73c42e12728f55a539180 484 SUPERFAMILY SSF53335 69 448 9.36E-70 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS00230 dac67cad29b73c42e12728f55a539180 484 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 126 448 1.2E-20 T 26-04-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A4V04_RS07710 3ebf8932fbc8b2905d3d88c6755e120d 453 Gene3D G3DSA:3.40.1190.10 92 310 2.6E-80 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS07710 3ebf8932fbc8b2905d3d88c6755e120d 453 Gene3D G3DSA:3.90.190.20 311 447 7.5E-34 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS07710 3ebf8932fbc8b2905d3d88c6755e120d 453 Pfam PF01225 Mur ligase family, catalytic domain 2 98 1.2E-15 T 26-04-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4V04_RS07710 3ebf8932fbc8b2905d3d88c6755e120d 453 Pfam PF08245 Mur ligase middle domain 108 289 1.4E-25 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS07710 3ebf8932fbc8b2905d3d88c6755e120d 453 SUPERFAMILY SSF51984 2 90 2.75E-20 T 26-04-2017 A4V04_RS07710 3ebf8932fbc8b2905d3d88c6755e120d 453 SUPERFAMILY SSF53244 308 446 1.83E-36 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS07710 3ebf8932fbc8b2905d3d88c6755e120d 453 Pfam PF02875 Mur ligase family, glutamate ligase domain 309 357 4.5E-11 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS07710 3ebf8932fbc8b2905d3d88c6755e120d 453 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 447 4.6E-189 T 26-04-2017 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 A4V04_RS07710 3ebf8932fbc8b2905d3d88c6755e120d 453 SUPERFAMILY SSF53623 99 306 2.09E-49 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS07710 3ebf8932fbc8b2905d3d88c6755e120d 453 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 447 53.089 T 26-04-2017 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 A4V04_RS07710 3ebf8932fbc8b2905d3d88c6755e120d 453 Gene3D G3DSA:3.40.50.720 2 90 1.1E-36 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS13050 0e651d2e3528addf5b3d44af32c0714b 597 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 483 588 5.1E-14 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS13050 0e651d2e3528addf5b3d44af32c0714b 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 570 1.1E-5 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS13050 0e651d2e3528addf5b3d44af32c0714b 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 534 1.1E-5 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS13050 0e651d2e3528addf5b3d44af32c0714b 597 Gene3D G3DSA:1.10.287.130 362 426 2.1E-5 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS13050 0e651d2e3528addf5b3d44af32c0714b 597 SUPERFAMILY SSF47384 359 429 1.88E-5 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS13050 0e651d2e3528addf5b3d44af32c0714b 597 SMART SM00387 481 592 3.0E-14 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS13050 0e651d2e3528addf5b3d44af32c0714b 597 SUPERFAMILY SSF53850 60 243 5.78E-15 T 26-04-2017 A4V04_RS13050 0e651d2e3528addf5b3d44af32c0714b 597 Gene3D G3DSA:3.30.565.10 427 590 8.6E-23 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS13050 0e651d2e3528addf5b3d44af32c0714b 597 SUPERFAMILY SSF55874 434 590 1.83E-23 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS13050 0e651d2e3528addf5b3d44af32c0714b 597 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 60 262 2.8E-17 T 26-04-2017 A4V04_RS13050 0e651d2e3528addf5b3d44af32c0714b 597 Gene3D G3DSA:3.40.190.10 113 205 4.1E-8 T 26-04-2017 A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 SUPERFAMILY SSF54862 208 307 2.51E-15 T 26-04-2017 A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 SUPERFAMILY SSF54862 353 418 2.51E-15 T 26-04-2017 A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 335 436 8.5E-21 T 26-04-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 Gene3D G3DSA:3.50.50.60 633 736 7.3E-15 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 Pfam PF00037 4Fe-4S binding domain 278 296 3.8E-5 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 SUPERFAMILY SSF46548 339 463 1.31E-23 T 26-04-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 355 366 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 Gene3D G3DSA:3.30.70.20 215 305 1.5E-10 T 26-04-2017 A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 SUPERFAMILY SSF51971 454 675 5.18E-45 T 26-04-2017 A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 Gene3D G3DSA:1.10.1060.10 332 454 2.6E-27 T 26-04-2017 A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 Pfam PF12801 4Fe-4S binding domain 59 94 1.2E-8 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 Pfam PF12801 4Fe-4S binding domain 202 236 0.0025 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 Pfam PF12801 4Fe-4S binding domain 43 49 450.0 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 Pfam PF12801 4Fe-4S binding domain 154 184 640.0 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 PRINTS PR00419 Adrenodoxin reductase family signature 585 599 3.1E-20 T 26-04-2017 A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 PRINTS PR00419 Adrenodoxin reductase family signature 477 490 3.1E-20 T 26-04-2017 A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 PRINTS PR00419 Adrenodoxin reductase family signature 454 476 3.1E-20 T 26-04-2017 A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 454 722 1.9E-27 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 Gene3D G3DSA:3.50.50.60 455 632 3.4E-42 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11430 3f11420a65bfcc90515ca95dc3162a17 766 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 280 291 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS09130 d0ec9b471d1d0730abdfce98396ba560 623 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 91 297 1.8E-19 T 26-04-2017 A4V04_RS09130 d0ec9b471d1d0730abdfce98396ba560 623 Gene3D G3DSA:3.30.565.10 453 614 5.3E-26 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS09130 d0ec9b471d1d0730abdfce98396ba560 623 Gene3D G3DSA:3.40.190.10 159 234 1.0E-6 T 26-04-2017 A4V04_RS09130 d0ec9b471d1d0730abdfce98396ba560 623 SUPERFAMILY SSF47384 386 464 8.04E-8 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS09130 d0ec9b471d1d0730abdfce98396ba560 623 SMART SM00387 507 616 2.7E-18 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS09130 d0ec9b471d1d0730abdfce98396ba560 623 SUPERFAMILY SSF53850 96 297 4.5E-10 T 26-04-2017 A4V04_RS09130 d0ec9b471d1d0730abdfce98396ba560 623 SUPERFAMILY SSF55874 457 612 2.1E-25 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS09130 d0ec9b471d1d0730abdfce98396ba560 623 Gene3D G3DSA:1.10.287.130 397 452 7.9E-5 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS09130 d0ec9b471d1d0730abdfce98396ba560 623 PRINTS PR00344 Bacterial sensor protein C-terminal signature 547 561 1.1E-6 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS09130 d0ec9b471d1d0730abdfce98396ba560 623 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 594 1.1E-6 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS09130 d0ec9b471d1d0730abdfce98396ba560 623 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 507 605 4.5E-13 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07725 037ef7e3924a603af6e9273cd894199e 153 SUPERFAMILY SSF51230 78 153 2.09E-25 T 26-04-2017 IPR011053 Single hybrid motif A4V04_RS07725 037ef7e3924a603af6e9273cd894199e 153 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 153 6.9E-54 T 26-04-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A4V04_RS07725 037ef7e3924a603af6e9273cd894199e 153 Gene3D G3DSA:2.40.50.100 76 153 4.7E-32 T 26-04-2017 A4V04_RS07725 037ef7e3924a603af6e9273cd894199e 153 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 109 126 - T 26-04-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4V04_RS07725 037ef7e3924a603af6e9273cd894199e 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 99 113 1.7E-19 T 26-04-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A4V04_RS07725 037ef7e3924a603af6e9273cd894199e 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 82 95 1.7E-19 T 26-04-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A4V04_RS07725 037ef7e3924a603af6e9273cd894199e 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 114 127 1.7E-19 T 26-04-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A4V04_RS07725 037ef7e3924a603af6e9273cd894199e 153 Pfam PF00364 Biotin-requiring enzyme 79 152 9.6E-24 T 26-04-2017 IPR000089 Biotin/lipoyl attachment A4V04_RS05495 5cd5e43ffb76a40db97edb27d50e377c 258 Pfam PF14393 Domain of unknown function (DUF4422) 4 222 7.1E-87 T 26-04-2017 IPR025536 Domain of unknown function DUF4422 A4V04_RS04520 9189149081cebece58bce3b9e93e905f 389 SMART SM00863 182 224 3.0E-13 T 26-04-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A4V04_RS04520 9189149081cebece58bce3b9e93e905f 389 SUPERFAMILY SSF50447 6 87 1.13E-15 T 26-04-2017 IPR009000 Translation protein, beta-barrel domain A4V04_RS04520 9189149081cebece58bce3b9e93e905f 389 Pfam PF01411 tRNA synthetases class II (A) 29 91 1.4E-9 T 26-04-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A4V04_RS04520 9189149081cebece58bce3b9e93e905f 389 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 182 215 6.2E-11 T 26-04-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A4V04_RS04520 9189149081cebece58bce3b9e93e905f 389 SUPERFAMILY SSF55186 88 228 1.57E-31 T 26-04-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 A4V04_RS12100 36068baf1ac1aca7965a8d3671c9c874 202 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 201 36.644 T 26-04-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A4V04_RS12100 36068baf1ac1aca7965a8d3671c9c874 202 Pfam PF00694 Aconitase C-terminal domain 1 122 9.3E-27 T 26-04-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS12100 36068baf1ac1aca7965a8d3671c9c874 202 Gene3D G3DSA:3.20.19.10 2 193 2.8E-39 T 26-04-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A4V04_RS12100 36068baf1ac1aca7965a8d3671c9c874 202 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 187 4.8E-57 T 26-04-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A4V04_RS12100 36068baf1ac1aca7965a8d3671c9c874 202 SUPERFAMILY SSF52016 1 191 8.83E-49 T 26-04-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 Pfam PF00308 Bacterial dnaA protein 120 339 3.4E-74 T 26-04-2017 IPR013317 Chromosomal replication initiator protein DnaA A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 Pfam PF11638 DnaA N-terminal domain 3 67 1.4E-10 T 26-04-2017 IPR024633 DnaA N-terminal domain A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 5 454 4.4E-140 T 26-04-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 Gene3D G3DSA:1.10.8.60 290 358 1.0E-25 T 26-04-2017 A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 SUPERFAMILY SSF48295 363 457 6.54E-32 T 26-04-2017 IPR010921 Trp repressor/replication initiator GO:0043565 A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 SMART SM00382 151 290 8.6E-7 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 367 434 1.4E-28 T 26-04-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 255 282 1.1E-39 T 26-04-2017 IPR020591 Chromosomal replication control, initiator DnaA-like A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 221 235 1.1E-39 T 26-04-2017 IPR020591 Chromosomal replication control, initiator DnaA-like A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 415 434 1.1E-39 T 26-04-2017 IPR020591 Chromosomal replication control, initiator DnaA-like A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 152 172 1.1E-39 T 26-04-2017 IPR020591 Chromosomal replication control, initiator DnaA-like A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 184 198 1.1E-39 T 26-04-2017 IPR020591 Chromosomal replication control, initiator DnaA-like A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 Gene3D G3DSA:1.10.1750.10 363 457 1.3E-35 T 26-04-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 SMART SM00760 365 434 1.0E-37 T 26-04-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 SUPERFAMILY SSF52540 119 335 7.16E-32 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 Gene3D G3DSA:3.40.50.300 110 288 1.5E-44 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 2 456 27.892 T 26-04-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A4V04_RS10480 b931867b829258d3f5f249f79897a2ef 459 ProSitePatterns PS01008 DnaA protein signature. 415 434 - T 26-04-2017 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A4V04_RS06645 4e0198216678068171bbb003584bafcb 222 SUPERFAMILY SSF161098 15 203 2.35E-51 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS06645 4e0198216678068171bbb003584bafcb 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 217 9.6E-24 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS06645 4e0198216678068171bbb003584bafcb 222 Gene3D G3DSA:1.10.3720.10 12 218 2.1E-54 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS06645 4e0198216678068171bbb003584bafcb 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 112 2.2E-33 T 26-04-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A4V04_RS02920 b8a3d265f5737051a37f51fb8422b112 232 SUPERFAMILY SSF57863 94 151 2.28E-8 T 26-04-2017 A4V04_RS02920 b8a3d265f5737051a37f51fb8422b112 232 Gene3D G3DSA:2.40.50.140 10 83 9.5E-12 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS02920 b8a3d265f5737051a37f51fb8422b112 232 Hamap MF_00201 DNA repair protein RecO [recO]. 10 229 19.947 T 26-04-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A4V04_RS02920 b8a3d265f5737051a37f51fb8422b112 232 TIGRFAM TIGR00613 reco: DNA repair protein RecO 15 153 1.3E-26 T 26-04-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A4V04_RS02920 b8a3d265f5737051a37f51fb8422b112 232 SUPERFAMILY SSF50249 12 84 4.11E-15 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS02920 b8a3d265f5737051a37f51fb8422b112 232 Pfam PF02565 Recombination protein O C terminal 94 153 3.7E-14 T 26-04-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A4V04_RS02920 b8a3d265f5737051a37f51fb8422b112 232 Pfam PF11967 Recombination protein O N terminal 13 84 3.5E-21 T 26-04-2017 IPR022572 DNA replication/recombination mediator RecO, N-terminal A4V04_RS08730 e2b354a5b02bf1b30313e08bb654b33a 439 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 35 216 7.5E-60 T 26-04-2017 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 A4V04_RS08730 e2b354a5b02bf1b30313e08bb654b33a 439 Gene3D G3DSA:3.40.50.2000 285 409 3.7E-5 T 26-04-2017 A4V04_RS08730 e2b354a5b02bf1b30313e08bb654b33a 439 SUPERFAMILY SSF53756 55 431 1.26E-17 T 26-04-2017 A4V04_RS08730 e2b354a5b02bf1b30313e08bb654b33a 439 Pfam PF00534 Glycosyl transferases group 1 313 409 4.3E-7 T 26-04-2017 IPR001296 Glycosyl transferase, family 1 A4V04_RS10940 f713946885a14e87eb256aa705d82dac 303 Pfam PF03466 LysR substrate binding domain 89 286 2.1E-15 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS10940 f713946885a14e87eb256aa705d82dac 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.0E-7 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10940 f713946885a14e87eb256aa705d82dac 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.0E-7 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10940 f713946885a14e87eb256aa705d82dac 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.0E-7 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10940 f713946885a14e87eb256aa705d82dac 303 Gene3D G3DSA:1.10.10.10 1 83 5.0E-27 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10940 f713946885a14e87eb256aa705d82dac 303 SUPERFAMILY SSF53850 89 291 1.39E-18 T 26-04-2017 A4V04_RS10940 f713946885a14e87eb256aa705d82dac 303 SUPERFAMILY SSF46785 1 83 1.02E-21 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10940 f713946885a14e87eb256aa705d82dac 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.2E-20 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10940 f713946885a14e87eb256aa705d82dac 303 Gene3D G3DSA:3.40.190.10 89 193 8.0E-14 T 26-04-2017 A4V04_RS10405 d171d4c8a38a2c89f4a1619dd0c7a9d1 100 Pfam PF04359 Protein of unknown function (DUF493) 18 100 9.5E-26 T 26-04-2017 IPR007454 Uncharacterised protein family UPF0250 A4V04_RS10405 d171d4c8a38a2c89f4a1619dd0c7a9d1 100 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 15 100 21.086 T 26-04-2017 IPR007454 Uncharacterised protein family UPF0250 A4V04_RS10405 d171d4c8a38a2c89f4a1619dd0c7a9d1 100 Gene3D G3DSA:3.30.70.1460 17 100 3.2E-25 T 26-04-2017 IPR027471 YbeD-like domain A4V04_RS10405 d171d4c8a38a2c89f4a1619dd0c7a9d1 100 SUPERFAMILY SSF117991 15 100 1.83E-23 T 26-04-2017 IPR027471 YbeD-like domain A4V04_RS10765 3852ad1a0fff1277c80afad397d75972 451 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 448 38.878 T 26-04-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 A4V04_RS10765 3852ad1a0fff1277c80afad397d75972 451 Gene3D G3DSA:3.90.550.10 1 246 4.4E-67 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS10765 3852ad1a0fff1277c80afad397d75972 451 Pfam PF12804 MobA-like NTP transferase domain 3 121 2.7E-23 T 26-04-2017 IPR025877 MobA-like NTP transferase A4V04_RS10765 3852ad1a0fff1277c80afad397d75972 451 SUPERFAMILY SSF51161 252 433 3.3E-51 T 26-04-2017 IPR011004 Trimeric LpxA-like A4V04_RS10765 3852ad1a0fff1277c80afad397d75972 451 Gene3D G3DSA:2.160.10.10 257 433 4.7E-49 T 26-04-2017 A4V04_RS10765 3852ad1a0fff1277c80afad397d75972 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 314 348 3.2E-4 T 26-04-2017 IPR001451 Hexapeptide repeat A4V04_RS10765 3852ad1a0fff1277c80afad397d75972 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 391 425 3.4E-7 T 26-04-2017 IPR001451 Hexapeptide repeat A4V04_RS10765 3852ad1a0fff1277c80afad397d75972 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 262 295 7.1E-7 T 26-04-2017 IPR001451 Hexapeptide repeat A4V04_RS10765 3852ad1a0fff1277c80afad397d75972 451 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 451 1.6E-181 T 26-04-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 A4V04_RS10765 3852ad1a0fff1277c80afad397d75972 451 SUPERFAMILY SSF53448 1 248 1.22E-57 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS11135 46bbac63394bc18830426fa1c26b1a17 230 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 1.9E-102 T 26-04-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A4V04_RS11135 46bbac63394bc18830426fa1c26b1a17 230 SUPERFAMILY SSF56808 6 226 6.15E-79 T 26-04-2017 IPR023674 Ribosomal protein L1-like A4V04_RS11135 46bbac63394bc18830426fa1c26b1a17 230 Gene3D G3DSA:3.30.190.20 17 68 1.1E-47 T 26-04-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 A4V04_RS11135 46bbac63394bc18830426fa1c26b1a17 230 Gene3D G3DSA:3.30.190.20 161 227 1.1E-47 T 26-04-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 A4V04_RS11135 46bbac63394bc18830426fa1c26b1a17 230 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.189 T 26-04-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A4V04_RS11135 46bbac63394bc18830426fa1c26b1a17 230 Gene3D G3DSA:3.40.50.790 69 159 9.3E-40 T 26-04-2017 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich A4V04_RS11135 46bbac63394bc18830426fa1c26b1a17 230 PIRSF PIRSF002155 1 227 1.6E-77 T 26-04-2017 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11135 46bbac63394bc18830426fa1c26b1a17 230 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 26-04-2017 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11135 46bbac63394bc18830426fa1c26b1a17 230 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 4.6E-51 T 26-04-2017 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein A4V04_RS06905 4dbf00867ee06b87ff506469b0a394c6 353 Gene3D G3DSA:3.40.1780.10 183 347 2.8E-96 T 26-04-2017 A4V04_RS06905 4dbf00867ee06b87ff506469b0a394c6 353 Gene3D G3DSA:3.40.1780.10 7 65 2.8E-96 T 26-04-2017 A4V04_RS06905 4dbf00867ee06b87ff506469b0a394c6 353 SUPERFAMILY SSF111337 7 347 1.29E-126 T 26-04-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A4V04_RS06905 4dbf00867ee06b87ff506469b0a394c6 353 Pfam PF02547 Queuosine biosynthesis protein 7 347 1.5E-130 T 26-04-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A4V04_RS06905 4dbf00867ee06b87ff506469b0a394c6 353 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 6 347 2.3E-131 T 26-04-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A4V04_RS06905 4dbf00867ee06b87ff506469b0a394c6 353 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 348 44.095 T 26-04-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A4V04_RS06905 4dbf00867ee06b87ff506469b0a394c6 353 Gene3D G3DSA:2.40.10.240 67 145 1.9E-12 T 26-04-2017 A4V04_RS12330 c4707e5646ac98427bf3ad1b2e3b8d5d 352 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 142 1.5E-37 T 26-04-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4V04_RS12330 c4707e5646ac98427bf3ad1b2e3b8d5d 352 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 4 346 40.553 T 26-04-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4V04_RS12330 c4707e5646ac98427bf3ad1b2e3b8d5d 352 Gene3D G3DSA:3.40.50.720 1 157 3.5E-61 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS12330 c4707e5646ac98427bf3ad1b2e3b8d5d 352 SUPERFAMILY SSF51735 2 168 4.41E-53 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS12330 c4707e5646ac98427bf3ad1b2e3b8d5d 352 SMART SM00859 5 143 5.5E-56 T 26-04-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4V04_RS12330 c4707e5646ac98427bf3ad1b2e3b8d5d 352 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 4 352 3.8E-123 T 26-04-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4V04_RS12330 c4707e5646ac98427bf3ad1b2e3b8d5d 352 Gene3D G3DSA:3.30.360.10 158 320 3.7E-53 T 26-04-2017 A4V04_RS12330 c4707e5646ac98427bf3ad1b2e3b8d5d 352 SUPERFAMILY SSF55347 151 320 3.16E-46 T 26-04-2017 A4V04_RS12330 c4707e5646ac98427bf3ad1b2e3b8d5d 352 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 178 323 1.4E-17 T 26-04-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4V04_RS12330 c4707e5646ac98427bf3ad1b2e3b8d5d 352 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 146 162 - T 26-04-2017 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4V04_RS05630 c3e1fd3ff4e0b006d5c568f62afd729b 221 Gene3D G3DSA:3.40.50.2300 17 158 6.3E-36 T 26-04-2017 A4V04_RS05630 c3e1fd3ff4e0b006d5c568f62afd729b 221 Pfam PF00072 Response regulator receiver domain 17 126 1.6E-27 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS05630 c3e1fd3ff4e0b006d5c568f62afd729b 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 196 1.3E-15 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS05630 c3e1fd3ff4e0b006d5c568f62afd729b 221 SUPERFAMILY SSF46894 139 210 2.35E-17 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS05630 c3e1fd3ff4e0b006d5c568f62afd729b 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 3.2E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS05630 c3e1fd3ff4e0b006d5c568f62afd729b 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 3.2E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS05630 c3e1fd3ff4e0b006d5c568f62afd729b 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 3.2E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS05630 c3e1fd3ff4e0b006d5c568f62afd729b 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS05630 c3e1fd3ff4e0b006d5c568f62afd729b 221 SMART SM00421 150 207 2.3E-15 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS05630 c3e1fd3ff4e0b006d5c568f62afd729b 221 SUPERFAMILY SSF52172 17 142 3.42E-34 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS05630 c3e1fd3ff4e0b006d5c568f62afd729b 221 SMART SM00448 15 126 2.8E-29 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS05630 c3e1fd3ff4e0b006d5c568f62afd729b 221 Gene3D G3DSA:1.10.10.10 159 210 4.7E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07405 116f3c60f17a165dccaa028ea9e91df9 246 Gene3D G3DSA:3.40.1280.10 95 245 6.2E-52 T 26-04-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4V04_RS07405 116f3c60f17a165dccaa028ea9e91df9 246 SMART SM00967 7 83 6.2E-17 T 26-04-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 A4V04_RS07405 116f3c60f17a165dccaa028ea9e91df9 246 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 5 245 40.101 T 26-04-2017 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB A4V04_RS07405 116f3c60f17a165dccaa028ea9e91df9 246 Gene3D G3DSA:3.30.1330.30 3 79 9.4E-20 T 26-04-2017 IPR029064 50S ribosomal protein L30e-like A4V04_RS07405 116f3c60f17a165dccaa028ea9e91df9 246 Pfam PF00588 SpoU rRNA Methylase family 98 238 3.4E-38 T 26-04-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4V04_RS07405 116f3c60f17a165dccaa028ea9e91df9 246 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 7 244 5.8E-68 T 26-04-2017 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 A4V04_RS07405 116f3c60f17a165dccaa028ea9e91df9 246 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 8 81 5.5E-18 T 26-04-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 A4V04_RS07405 116f3c60f17a165dccaa028ea9e91df9 246 SUPERFAMILY SSF75217 89 245 1.5E-45 T 26-04-2017 IPR029028 Alpha/beta knot methyltransferases A4V04_RS07405 116f3c60f17a165dccaa028ea9e91df9 246 SUPERFAMILY SSF55315 2 79 2.59E-17 T 26-04-2017 IPR029064 50S ribosomal protein L30e-like A4V04_RS12805 dba1a9bab57bc0aa4c4dec862e26f822 441 SUPERFAMILY SSF103473 58 432 1.44E-32 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS12805 dba1a9bab57bc0aa4c4dec862e26f822 441 Gene3D G3DSA:1.20.1250.20 258 432 6.0E-15 T 26-04-2017 A4V04_RS12805 dba1a9bab57bc0aa4c4dec862e26f822 441 Gene3D G3DSA:1.20.1250.20 61 242 8.4E-14 T 26-04-2017 A4V04_RS12805 dba1a9bab57bc0aa4c4dec862e26f822 441 Pfam PF07690 Major Facilitator Superfamily 67 386 1.2E-19 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS11545 daa71549ce8127e5fb17851e9e3f5d7a 488 SUPERFAMILY SSF56425 278 425 3.35E-23 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11545 daa71549ce8127e5fb17851e9e3f5d7a 488 Pfam PF00890 FAD binding domain 30 464 7.5E-63 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11545 daa71549ce8127e5fb17851e9e3f5d7a 488 Gene3D G3DSA:3.90.700.10 281 416 1.5E-24 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11545 daa71549ce8127e5fb17851e9e3f5d7a 488 Gene3D G3DSA:3.50.50.60 421 482 5.0E-70 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11545 daa71549ce8127e5fb17851e9e3f5d7a 488 Gene3D G3DSA:3.50.50.60 26 255 5.0E-70 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11545 daa71549ce8127e5fb17851e9e3f5d7a 488 SUPERFAMILY SSF51905 424 485 3.46E-44 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11545 daa71549ce8127e5fb17851e9e3f5d7a 488 SUPERFAMILY SSF51905 25 261 3.46E-44 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS13140 dd844f24669846b6a57507378cb81b32 200 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 8 157 1.0E-39 T 26-04-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4V04_RS13140 dd844f24669846b6a57507378cb81b32 200 SUPERFAMILY SSF53098 7 158 1.44E-43 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS13140 dd844f24669846b6a57507378cb81b32 200 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 65 81 6.2E-30 T 26-04-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4V04_RS13140 dd844f24669846b6a57507378cb81b32 200 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 9 22 6.2E-30 T 26-04-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4V04_RS13140 dd844f24669846b6a57507378cb81b32 200 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 111 130 6.2E-30 T 26-04-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4V04_RS13140 dd844f24669846b6a57507378cb81b32 200 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 143 155 6.2E-30 T 26-04-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4V04_RS13140 dd844f24669846b6a57507378cb81b32 200 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 87 103 6.2E-30 T 26-04-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4V04_RS13140 dd844f24669846b6a57507378cb81b32 200 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 117 152 - T 26-04-2017 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 A4V04_RS13140 dd844f24669846b6a57507378cb81b32 200 Gene3D G3DSA:3.30.420.10 7 159 9.7E-54 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS13140 dd844f24669846b6a57507378cb81b32 200 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 6 158 40.089 T 26-04-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4V04_RS13140 dd844f24669846b6a57507378cb81b32 200 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 8 154 4.7E-42 T 26-04-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4V04_RS11955 69a9bc274345cf4e392482290b77e9c7 293 SUPERFAMILY SSF52540 55 264 6.2E-24 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11955 69a9bc274345cf4e392482290b77e9c7 293 Gene3D G3DSA:3.40.50.300 61 195 6.6E-15 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11955 69a9bc274345cf4e392482290b77e9c7 293 Pfam PF05673 Protein of unknown function (DUF815) 34 286 1.2E-98 T 26-04-2017 IPR008533 Domain of unknown function DUF815 A4V04_RS02790 ec225003c98e4df1e273b374618eed83 529 Pfam PF08011 PD-(D/E)XK nuclease superfamily 429 525 7.1E-13 T 26-04-2017 IPR012547 PD-(D/E)XK nuclease superfamily 9 A4V04_RS02790 ec225003c98e4df1e273b374618eed83 529 Pfam PF09820 Predicted AAA-ATPase 10 285 5.8E-75 T 26-04-2017 IPR018631 AAA-ATPase-like domain A4V04_RS00185 455f45cbedb452a1ff4eab28f61a9ddd 65 SUPERFAMILY SSF143034 2 64 3.14E-22 T 26-04-2017 A4V04_RS00185 455f45cbedb452a1ff4eab28f61a9ddd 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.6E-17 T 26-04-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4V04_RS00185 455f45cbedb452a1ff4eab28f61a9ddd 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.6E-17 T 26-04-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4V04_RS00185 455f45cbedb452a1ff4eab28f61a9ddd 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.6E-17 T 26-04-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4V04_RS00185 455f45cbedb452a1ff4eab28f61a9ddd 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 26-04-2017 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS00185 455f45cbedb452a1ff4eab28f61a9ddd 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.807 T 26-04-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4V04_RS00185 455f45cbedb452a1ff4eab28f61a9ddd 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 6.5E-24 T 26-04-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4V04_RS00185 455f45cbedb452a1ff4eab28f61a9ddd 65 Pfam PF01632 Ribosomal protein L35 2 62 1.9E-22 T 26-04-2017 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS01565 9218b6334b3f9f0394ae1db84090a700 565 Pfam PF04205 FMN-binding domain 37 108 1.3E-13 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS01565 9218b6334b3f9f0394ae1db84090a700 565 Gene3D G3DSA:3.90.700.10 371 501 3.5E-36 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS01565 9218b6334b3f9f0394ae1db84090a700 565 SUPERFAMILY SSF56425 372 510 6.58E-35 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS01565 9218b6334b3f9f0394ae1db84090a700 565 SMART SM00900 37 111 2.0E-14 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS01565 9218b6334b3f9f0394ae1db84090a700 565 Pfam PF00890 FAD binding domain 137 539 3.2E-61 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS01565 9218b6334b3f9f0394ae1db84090a700 565 Gene3D G3DSA:3.50.50.60 125 357 5.3E-66 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS01565 9218b6334b3f9f0394ae1db84090a700 565 Gene3D G3DSA:3.50.50.60 506 560 5.3E-66 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS01565 9218b6334b3f9f0394ae1db84090a700 565 SUPERFAMILY SSF51905 509 563 1.15E-50 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS01565 9218b6334b3f9f0394ae1db84090a700 565 SUPERFAMILY SSF51905 125 362 1.15E-50 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS01565 9218b6334b3f9f0394ae1db84090a700 565 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 157 4.5E-5 T 26-04-2017 A4V04_RS01565 9218b6334b3f9f0394ae1db84090a700 565 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 304 322 4.5E-5 T 26-04-2017 A4V04_RS00295 ea4545ed4931fc7196e651b1587fa0f4 385 SUPERFAMILY SSF52540 203 376 1.33E-41 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00295 ea4545ed4931fc7196e651b1587fa0f4 385 Gene3D G3DSA:3.40.50.300 202 366 1.3E-37 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00295 ea4545ed4931fc7196e651b1587fa0f4 385 Pfam PF01926 50S ribosome-binding GTPase 205 323 1.8E-20 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS00295 ea4545ed4931fc7196e651b1587fa0f4 385 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 226 244 4.3E-9 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS00295 ea4545ed4931fc7196e651b1587fa0f4 385 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 272 290 4.3E-9 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS00295 ea4545ed4931fc7196e651b1587fa0f4 385 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 205 225 4.3E-9 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS00295 ea4545ed4931fc7196e651b1587fa0f4 385 Pfam PF13167 GTP-binding GTPase N-terminal 30 115 1.4E-26 T 26-04-2017 IPR025121 GTPase HflX, N-terminal A4V04_RS00295 ea4545ed4931fc7196e651b1587fa0f4 385 Pfam PF16360 GTP-binding GTPase Middle Region 118 197 9.2E-28 T 26-04-2017 IPR032305 GTP-binding protein, middle domain A4V04_RS00295 ea4545ed4931fc7196e651b1587fa0f4 385 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 15 363 5.5E-142 T 26-04-2017 IPR016496 GTPase HflX GO:0005525 A4V04_RS00295 ea4545ed4931fc7196e651b1587fa0f4 385 Hamap MF_00900 GTPase HflX [hflX]. 31 380 43.708 T 26-04-2017 IPR016496 GTPase HflX GO:0005525 A4V04_RS00295 ea4545ed4931fc7196e651b1587fa0f4 385 PIRSF PIRSF006809 6 382 7.3E-139 T 26-04-2017 IPR016496 GTPase HflX GO:0005525 A4V04_RS05405 7eed43a1529e7c6fbc7a0a5ffcb74d7b 254 SUPERFAMILY SSF52172 12 137 2.99E-41 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS05405 7eed43a1529e7c6fbc7a0a5ffcb74d7b 254 SUPERFAMILY SSF46894 144 246 5.95E-28 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS05405 7eed43a1529e7c6fbc7a0a5ffcb74d7b 254 Pfam PF00486 Transcriptional regulatory protein, C terminal 169 244 2.4E-22 T 26-04-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4V04_RS05405 7eed43a1529e7c6fbc7a0a5ffcb74d7b 254 SMART SM00862 168 244 5.5E-24 T 26-04-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4V04_RS05405 7eed43a1529e7c6fbc7a0a5ffcb74d7b 254 SMART SM00448 16 127 2.8E-41 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS05405 7eed43a1529e7c6fbc7a0a5ffcb74d7b 254 Pfam PF00072 Response regulator receiver domain 18 127 5.6E-29 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS05405 7eed43a1529e7c6fbc7a0a5ffcb74d7b 254 Gene3D G3DSA:1.10.10.10 146 246 2.1E-32 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS05405 7eed43a1529e7c6fbc7a0a5ffcb74d7b 254 Gene3D G3DSA:3.40.50.2300 13 136 5.2E-41 T 26-04-2017 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 TIGRFAM TIGR00492 alr: alanine racemase 5 360 6.7E-95 T 26-04-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 SUPERFAMILY SSF51419 9 237 5.79E-49 T 26-04-2017 IPR029066 PLP-binding barrel A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 Pfam PF00842 Alanine racemase, C-terminal domain 236 358 4.8E-37 T 26-04-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 Pfam PF01168 Alanine racemase, N-terminal domain 9 222 1.4E-48 T 26-04-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 Hamap MF_01201 Alanine racemase. 2 360 29.946 T 26-04-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 PRINTS PR00992 Alanine racemase signature 27 43 2.4E-60 T 26-04-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 PRINTS PR00992 Alanine racemase signature 121 133 2.4E-60 T 26-04-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 PRINTS PR00992 Alanine racemase signature 269 284 2.4E-60 T 26-04-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 PRINTS PR00992 Alanine racemase signature 342 355 2.4E-60 T 26-04-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 PRINTS PR00992 Alanine racemase signature 155 166 2.4E-60 T 26-04-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 PRINTS PR00992 Alanine racemase signature 61 79 2.4E-60 T 26-04-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 PRINTS PR00992 Alanine racemase signature 290 307 2.4E-60 T 26-04-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 PRINTS PR00992 Alanine racemase signature 195 222 2.4E-60 T 26-04-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 PRINTS PR00992 Alanine racemase signature 252 267 2.4E-60 T 26-04-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 32 42 - T 26-04-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 SMART SM01005 236 360 4.7E-61 T 26-04-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 Gene3D G3DSA:3.20.20.10 12 215 3.0E-51 T 26-04-2017 IPR029066 PLP-binding barrel A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 Gene3D G3DSA:2.40.37.10 216 360 1.7E-53 T 26-04-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4V04_RS03210 3962c97fad7a25182e9ed4f07ce35e8d 361 SUPERFAMILY SSF50621 229 360 4.19E-45 T 26-04-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4V04_RS05870 8ac5dd05561787bce58e18b09e6ca137 453 Pfam PF13180 PDZ domain 217 290 8.3E-9 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS05870 8ac5dd05561787bce58e18b09e6ca137 453 Gene3D G3DSA:2.30.42.10 100 190 7.5E-17 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS05870 8ac5dd05561787bce58e18b09e6ca137 453 Pfam PF02163 Peptidase family M50 9 438 2.6E-78 T 26-04-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 A4V04_RS05870 8ac5dd05561787bce58e18b09e6ca137 453 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 452 4.4E-106 T 26-04-2017 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 A4V04_RS05870 8ac5dd05561787bce58e18b09e6ca137 453 SUPERFAMILY SSF50156 93 190 1.45E-14 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS05870 8ac5dd05561787bce58e18b09e6ca137 453 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 135 187 5.5E-8 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS05870 8ac5dd05561787bce58e18b09e6ca137 453 SMART SM00228 120 190 1.2E-5 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS05870 8ac5dd05561787bce58e18b09e6ca137 453 SMART SM00228 216 283 7.8E-7 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS05870 8ac5dd05561787bce58e18b09e6ca137 453 SUPERFAMILY SSF50156 218 293 1.16E-13 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS05870 8ac5dd05561787bce58e18b09e6ca137 453 Gene3D G3DSA:2.30.42.10 214 300 3.0E-16 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS10090 fcf139b005b4edb153c0e0cea5473f32 458 SUPERFAMILY SSF53098 142 299 1.12E-13 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS10090 fcf139b005b4edb153c0e0cea5473f32 458 Gene3D G3DSA:3.30.420.10 142 299 2.4E-16 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS04610 fcf139b005b4edb153c0e0cea5473f32 458 SUPERFAMILY SSF53098 142 299 1.12E-13 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS04610 fcf139b005b4edb153c0e0cea5473f32 458 Gene3D G3DSA:3.30.420.10 142 299 2.4E-16 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS03855 fcf139b005b4edb153c0e0cea5473f32 458 SUPERFAMILY SSF53098 142 299 1.12E-13 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS03855 fcf139b005b4edb153c0e0cea5473f32 458 Gene3D G3DSA:3.30.420.10 142 299 2.4E-16 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS03860 fcf139b005b4edb153c0e0cea5473f32 458 SUPERFAMILY SSF53098 142 299 1.12E-13 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS03860 fcf139b005b4edb153c0e0cea5473f32 458 Gene3D G3DSA:3.30.420.10 142 299 2.4E-16 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS04070 fcf139b005b4edb153c0e0cea5473f32 458 SUPERFAMILY SSF53098 142 299 1.12E-13 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS04070 fcf139b005b4edb153c0e0cea5473f32 458 Gene3D G3DSA:3.30.420.10 142 299 2.4E-16 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS10085 fcf139b005b4edb153c0e0cea5473f32 458 SUPERFAMILY SSF53098 142 299 1.12E-13 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS10085 fcf139b005b4edb153c0e0cea5473f32 458 Gene3D G3DSA:3.30.420.10 142 299 2.4E-16 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS10080 fcf139b005b4edb153c0e0cea5473f32 458 SUPERFAMILY SSF53098 142 299 1.12E-13 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS10080 fcf139b005b4edb153c0e0cea5473f32 458 Gene3D G3DSA:3.30.420.10 142 299 2.4E-16 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS09050 4658563a442d1283bfe099b43c0b6f41 273 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 273 40.137 T 26-04-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A4V04_RS09050 4658563a442d1283bfe099b43c0b6f41 273 Gene3D G3DSA:3.20.190.10 2 130 4.9E-30 T 26-04-2017 A4V04_RS09050 4658563a442d1283bfe099b43c0b6f41 273 ProSitePatterns PS01242 Zinc finger FPG-type signature. 248 272 - T 26-04-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 A4V04_RS09050 4658563a442d1283bfe099b43c0b6f41 273 SUPERFAMILY SSF57716 221 272 3.71E-17 T 26-04-2017 A4V04_RS09050 4658563a442d1283bfe099b43c0b6f41 273 SUPERFAMILY SSF46946 134 225 7.33E-26 T 26-04-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4V04_RS09050 4658563a442d1283bfe099b43c0b6f41 273 SUPERFAMILY SSF81624 2 142 3.01E-33 T 26-04-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4V04_RS09050 4658563a442d1283bfe099b43c0b6f41 273 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 272 1.1E-84 T 26-04-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A4V04_RS09050 4658563a442d1283bfe099b43c0b6f41 273 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 6.4E-26 T 26-04-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4V04_RS09050 4658563a442d1283bfe099b43c0b6f41 273 Pfam PF06827 Zinc finger found in FPG and IleRS 245 273 7.1E-12 T 26-04-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A4V04_RS09050 4658563a442d1283bfe099b43c0b6f41 273 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 133 222 9.2E-24 T 26-04-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4V04_RS09050 4658563a442d1283bfe099b43c0b6f41 273 Gene3D G3DSA:1.10.8.50 133 273 1.6E-46 T 26-04-2017 A4V04_RS09050 4658563a442d1283bfe099b43c0b6f41 273 SMART SM01232 133 225 3.2E-35 T 26-04-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4V04_RS09050 4658563a442d1283bfe099b43c0b6f41 273 SMART SM00898 2 116 3.5E-39 T 26-04-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4V04_RS10270 0834108720d2d8baa4734f6560ace274 311 SUPERFAMILY SSF53850 100 308 4.24E-38 T 26-04-2017 A4V04_RS10270 0834108720d2d8baa4734f6560ace274 311 Gene3D G3DSA:1.10.10.10 10 89 3.1E-26 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10270 0834108720d2d8baa4734f6560ace274 311 SUPERFAMILY SSF46785 10 121 1.56E-24 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10270 0834108720d2d8baa4734f6560ace274 311 Pfam PF03466 LysR substrate binding domain 97 306 1.5E-41 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS10270 0834108720d2d8baa4734f6560ace274 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 3.5E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10270 0834108720d2d8baa4734f6560ace274 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 3.5E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10270 0834108720d2d8baa4734f6560ace274 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 3.5E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10270 0834108720d2d8baa4734f6560ace274 311 Gene3D G3DSA:3.40.190.10 182 272 1.7E-12 T 26-04-2017 A4V04_RS10270 0834108720d2d8baa4734f6560ace274 311 Gene3D G3DSA:3.40.190.10 100 181 2.2E-17 T 26-04-2017 A4V04_RS10270 0834108720d2d8baa4734f6560ace274 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 71 3.0E-21 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS11145 11acea82e4b07c1470c044c34994f65e 125 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 59 125 3.6E-30 T 26-04-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11145 11acea82e4b07c1470c044c34994f65e 125 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 125 26.303 T 26-04-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11145 11acea82e4b07c1470c044c34994f65e 125 Gene3D G3DSA:1.20.5.710 2 51 1.8E-22 T 26-04-2017 A4V04_RS11145 11acea82e4b07c1470c044c34994f65e 125 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 125 1.4E-47 T 26-04-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11145 11acea82e4b07c1470c044c34994f65e 125 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 2.6E-19 T 26-04-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11145 11acea82e4b07c1470c044c34994f65e 125 Gene3D G3DSA:3.30.1390.10 54 125 2.0E-33 T 26-04-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4V04_RS11145 11acea82e4b07c1470c044c34994f65e 125 SUPERFAMILY SSF48300 4 61 1.44E-17 T 26-04-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11145 11acea82e4b07c1470c044c34994f65e 125 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 99 1.0E-10 T 26-04-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11145 11acea82e4b07c1470c044c34994f65e 125 SUPERFAMILY SSF54736 54 125 1.15E-24 T 26-04-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4V04_RS04585 08b235e55a71ddf2742203742d0115aa 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS04585 08b235e55a71ddf2742203742d0115aa 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS04585 08b235e55a71ddf2742203742d0115aa 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS04585 08b235e55a71ddf2742203742d0115aa 318 Gene3D G3DSA:3.40.190.10 88 177 2.6E-21 T 26-04-2017 A4V04_RS04585 08b235e55a71ddf2742203742d0115aa 318 Gene3D G3DSA:1.10.10.10 2 80 4.0E-24 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04585 08b235e55a71ddf2742203742d0115aa 318 SUPERFAMILY SSF46785 2 81 8.61E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04585 08b235e55a71ddf2742203742d0115aa 318 Pfam PF03466 LysR substrate binding domain 87 295 1.9E-36 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS04585 08b235e55a71ddf2742203742d0115aa 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.3E-17 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS04585 08b235e55a71ddf2742203742d0115aa 318 SUPERFAMILY SSF53850 87 295 2.58E-31 T 26-04-2017 A4V04_RS04585 08b235e55a71ddf2742203742d0115aa 318 Gene3D G3DSA:3.40.190.10 178 272 6.1E-24 T 26-04-2017 A4V04_RS11445 cbf4017ace407b1c9a4db7ffebcbb702 317 Gene3D G3DSA:1.10.10.10 10 90 1.6E-13 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS11445 cbf4017ace407b1c9a4db7ffebcbb702 317 SUPERFAMILY SSF53850 96 300 1.18E-18 T 26-04-2017 A4V04_RS11445 cbf4017ace407b1c9a4db7ffebcbb702 317 Pfam PF03466 LysR substrate binding domain 96 296 2.9E-13 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS11445 cbf4017ace407b1c9a4db7ffebcbb702 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 6.8E-10 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS11445 cbf4017ace407b1c9a4db7ffebcbb702 317 SUPERFAMILY SSF46785 10 88 1.43E-10 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS11445 cbf4017ace407b1c9a4db7ffebcbb702 317 Gene3D G3DSA:3.40.190.10 182 266 4.0E-11 T 26-04-2017 A4V04_RS11445 cbf4017ace407b1c9a4db7ffebcbb702 317 Gene3D G3DSA:3.40.190.10 96 181 3.5E-8 T 26-04-2017 A4V04_RS07440 81b745beb39c4c23ee29094177fef9eb 248 Pfam PF00899 ThiF family 8 240 1.4E-60 T 26-04-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A4V04_RS07440 81b745beb39c4c23ee29094177fef9eb 248 Gene3D G3DSA:3.40.50.720 3 244 3.9E-73 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS07440 81b745beb39c4c23ee29094177fef9eb 248 SUPERFAMILY SSF69572 5 245 7.59E-80 T 26-04-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A4V04_RS01485 d59d0f6b49a761d7f50a029a747607e9 378 SUPERFAMILY SSF48600 11 97 1.79E-19 T 26-04-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4V04_RS01485 d59d0f6b49a761d7f50a029a747607e9 378 SUPERFAMILY SSF55021 266 364 5.36E-24 T 26-04-2017 A4V04_RS01485 d59d0f6b49a761d7f50a029a747607e9 378 Pfam PF01817 Chorismate mutase type II 16 93 2.9E-21 T 26-04-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4V04_RS01485 d59d0f6b49a761d7f50a029a747607e9 378 Pfam PF00800 Prephenate dehydratase 97 272 3.6E-62 T 26-04-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A4V04_RS01485 d59d0f6b49a761d7f50a029a747607e9 378 Gene3D G3DSA:3.40.190.10 182 259 2.4E-24 T 26-04-2017 A4V04_RS01485 d59d0f6b49a761d7f50a029a747607e9 378 PIRSF PIRSF001500 5 366 9.6E-132 T 26-04-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A4V04_RS01485 d59d0f6b49a761d7f50a029a747607e9 378 SMART SM00830 16 95 1.7E-25 T 26-04-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4V04_RS01485 d59d0f6b49a761d7f50a029a747607e9 378 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 312 319 - T 26-04-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A4V04_RS01485 d59d0f6b49a761d7f50a029a747607e9 378 Gene3D G3DSA:3.40.190.10 93 181 5.0E-32 T 26-04-2017 A4V04_RS01485 d59d0f6b49a761d7f50a029a747607e9 378 Gene3D G3DSA:1.20.59.10 3 92 3.0E-22 T 26-04-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4V04_RS01485 d59d0f6b49a761d7f50a029a747607e9 378 SUPERFAMILY SSF53850 96 277 4.67E-56 T 26-04-2017 A4V04_RS01485 d59d0f6b49a761d7f50a029a747607e9 378 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 247 269 - T 26-04-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A4V04_RS01485 d59d0f6b49a761d7f50a029a747607e9 378 Gene3D G3DSA:3.30.70.260 280 364 4.6E-28 T 26-04-2017 A4V04_RS09815 c9b96d8708480a1333aab378d5b01b32 485 Pfam PF01425 Amidase 25 465 2.1E-142 T 26-04-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4V04_RS09815 c9b96d8708480a1333aab378d5b01b32 485 SUPERFAMILY SSF75304 1 482 9.81E-152 T 26-04-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4V04_RS09815 c9b96d8708480a1333aab378d5b01b32 485 Gene3D G3DSA:3.90.1300.10 1 482 1.3E-170 T 26-04-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4V04_RS09815 c9b96d8708480a1333aab378d5b01b32 485 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 14 476 2.5E-167 T 26-04-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4V04_RS09815 c9b96d8708480a1333aab378d5b01b32 485 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 476 84.341 T 26-04-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4V04_RS09815 c9b96d8708480a1333aab378d5b01b32 485 ProSitePatterns PS00571 Amidases signature. 151 182 - T 26-04-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 A4V04_RS07190 cd34f5adee2d1aecdba51af128dddf10 344 Gene3D G3DSA:3.30.470.10 2 162 5.7E-68 T 26-04-2017 A4V04_RS07190 cd34f5adee2d1aecdba51af128dddf10 344 SUPERFAMILY SSF56752 3 337 1.1E-99 T 26-04-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A4V04_RS07190 cd34f5adee2d1aecdba51af128dddf10 344 Gene3D G3DSA:3.20.10.10 163 326 1.7E-52 T 26-04-2017 A4V04_RS07190 cd34f5adee2d1aecdba51af128dddf10 344 Pfam PF01063 Amino-transferase class IV 57 292 1.1E-30 T 26-04-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A4V04_RS07190 cd34f5adee2d1aecdba51af128dddf10 344 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 31 339 8.7E-108 T 26-04-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 A4V04_RS07190 cd34f5adee2d1aecdba51af128dddf10 344 PIRSF PIRSF006468 1 342 2.2E-117 T 26-04-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 Gene3D G3DSA:3.40.50.300 135 309 2.8E-59 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 SUPERFAMILY SSF52540 136 380 5.55E-75 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 Pfam PF02954 Bacterial regulatory protein, Fis family 439 478 1.9E-10 T 26-04-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 4 477 2.6E-205 T 26-04-2017 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 223 238 - T 26-04-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 SMART SM00382 157 304 1.8E-13 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 Gene3D G3DSA:1.10.8.60 310 387 3.5E-24 T 26-04-2017 A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 Pfam PF00072 Response regulator receiver domain 4 114 1.4E-24 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 Gene3D G3DSA:3.40.50.2300 1 126 3.2E-30 T 26-04-2017 A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 444 461 9.9E-8 T 26-04-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 461 481 9.9E-8 T 26-04-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 Gene3D G3DSA:1.10.10.60 414 481 2.5E-15 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 161 174 - T 26-04-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 350 359 - T 26-04-2017 IPR025944 Sigma-54 interaction domain, conserved site A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 Pfam PF00158 Sigma-54 interaction domain 137 303 1.8E-68 T 26-04-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 SUPERFAMILY SSF52172 1 182 1.41E-37 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 SUPERFAMILY SSF46689 410 481 9.41E-15 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS05655 583961d1ef06cd3ac60573a237affa75 481 SMART SM00448 2 114 4.7E-29 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS10435 cd8c5d161d9a128d89ac4d45e0ec5e3c 245 Pfam PF00005 ABC transporter 25 162 1.4E-30 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS10435 cd8c5d161d9a128d89ac4d45e0ec5e3c 245 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS10435 cd8c5d161d9a128d89ac4d45e0ec5e3c 245 SUPERFAMILY SSF52540 5 226 5.09E-62 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10435 cd8c5d161d9a128d89ac4d45e0ec5e3c 245 SMART SM00382 33 212 1.6E-11 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS10435 cd8c5d161d9a128d89ac4d45e0ec5e3c 245 Gene3D G3DSA:3.40.50.300 5 217 7.0E-59 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06770 bec28939b4039dc2497692e82912d440 244 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 43 224 6.2E-66 T 26-04-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06770 bec28939b4039dc2497692e82912d440 244 Pfam PF01578 Cytochrome C assembly protein 26 182 2.3E-28 T 26-04-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A4V04_RS06770 bec28939b4039dc2497692e82912d440 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 43 60 1.4E-43 T 26-04-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06770 bec28939b4039dc2497692e82912d440 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 98 118 1.4E-43 T 26-04-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06770 bec28939b4039dc2497692e82912d440 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 154 180 1.4E-43 T 26-04-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06770 bec28939b4039dc2497692e82912d440 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 60 80 1.4E-43 T 26-04-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06770 bec28939b4039dc2497692e82912d440 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 119 139 1.4E-43 T 26-04-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06770 bec28939b4039dc2497692e82912d440 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 201 225 1.4E-43 T 26-04-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS05110 5ee7e58182898c995c81e47cbd2db68b 142 Pfam PF03061 Thioesterase superfamily 45 124 1.2E-11 T 26-04-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 A4V04_RS05110 5ee7e58182898c995c81e47cbd2db68b 142 Gene3D G3DSA:3.10.129.10 12 137 1.3E-38 T 26-04-2017 IPR029069 HotDog domain A4V04_RS05110 5ee7e58182898c995c81e47cbd2db68b 142 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 15 130 1.3E-20 T 26-04-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 A4V04_RS05110 5ee7e58182898c995c81e47cbd2db68b 142 SUPERFAMILY SSF54637 14 137 3.85E-25 T 26-04-2017 IPR029069 HotDog domain A4V04_RS06950 ffedc49009246075a8c09370b89adda5 197 SUPERFAMILY SSF53697 6 188 7.97E-47 T 26-04-2017 A4V04_RS06950 ffedc49009246075a8c09370b89adda5 197 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 3 192 33.279 T 26-04-2017 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 A4V04_RS06950 ffedc49009246075a8c09370b89adda5 197 Pfam PF13580 SIS domain 25 148 2.7E-27 T 26-04-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4V04_RS06950 ffedc49009246075a8c09370b89adda5 197 Gene3D G3DSA:3.40.50.10490 7 189 1.2E-55 T 26-04-2017 A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 SMART SM00388 524 596 7.6E-11 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 SMART SM00304 335 387 2.1E-6 T 26-04-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 Gene3D G3DSA:1.10.287.130 519 592 5.0E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 SUPERFAMILY SSF158472 336 384 9.42E-8 T 26-04-2017 A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 SUPERFAMILY SSF47384 518 597 3.34E-12 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 Pfam PF00512 His Kinase A (phospho-acceptor) domain 527 595 2.2E-10 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 SMART SM00387 634 754 1.3E-28 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 PIRSF PIRSF037532 1 755 6.2E-186 T 26-04-2017 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 Pfam PF00672 HAMP domain 317 383 1.7E-10 T 26-04-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 SUPERFAMILY SSF55785 391 514 1.21E-9 T 26-04-2017 IPR000014 PAS domain A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 Gene3D G3DSA:3.30.450.20 392 514 6.0E-11 T 26-04-2017 A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 PRINTS PR00344 Bacterial sensor protein C-terminal signature 709 727 1.4E-9 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 PRINTS PR00344 Bacterial sensor protein C-terminal signature 698 708 1.4E-9 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 PRINTS PR00344 Bacterial sensor protein C-terminal signature 680 694 1.4E-9 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 SUPERFAMILY SSF55874 582 748 3.14E-31 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 635 748 1.9E-16 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS09965 005917e08e6d07f2f620b4b51d8f7b76 755 Gene3D G3DSA:3.30.565.10 597 735 1.2E-32 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 PRINTS PR00149 Fumarate lyase superfamily signature 186 204 7.7E-34 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 PRINTS PR00149 Fumarate lyase superfamily signature 323 339 7.7E-34 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 PRINTS PR00149 Fumarate lyase superfamily signature 277 304 7.7E-34 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 PRINTS PR00149 Fumarate lyase superfamily signature 140 158 7.7E-34 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 4 466 5.2E-219 T 26-04-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 Gene3D G3DSA:1.20.200.10 145 409 7.0E-101 T 26-04-2017 A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 Pfam PF00206 Lyase 12 348 6.6E-110 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 Pfam PF10415 Fumarase C C-terminus 414 466 5.6E-19 T 26-04-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 ProSitePatterns PS00163 Fumarate lyases signature. 323 332 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 SUPERFAMILY SSF48557 3 466 4.08E-147 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 Hamap MF_00743 Fumarate hydratase class II [fumC]. 4 468 83.268 T 26-04-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 PRINTS PR00145 Argininosuccinate lyase family signature 181 201 8.3E-7 T 26-04-2017 A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 PRINTS PR00145 Argininosuccinate lyase family signature 139 161 8.3E-7 T 26-04-2017 A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 PRINTS PR00145 Argininosuccinate lyase family signature 323 339 8.3E-7 T 26-04-2017 A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 Gene3D G3DSA:1.10.40.30 411 469 5.6E-24 T 26-04-2017 A4V04_RS11820 2a2bf399246f651af1a20c960a25f1f2 470 Gene3D G3DSA:1.10.275.10 3 144 2.4E-56 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 PRINTS PR00987 Glutamyl-tRNA synthetase signature 72 83 8.6E-10 T 26-04-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 PRINTS PR00987 Glutamyl-tRNA synthetase signature 87 100 8.6E-10 T 26-04-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 PRINTS PR00987 Glutamyl-tRNA synthetase signature 241 251 8.6E-10 T 26-04-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 PRINTS PR00987 Glutamyl-tRNA synthetase signature 58 70 8.6E-10 T 26-04-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 Gene3D G3DSA:2.40.240.10 603 689 6.5E-29 T 26-04-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 385 470 8.4E-15 T 26-04-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 54 276 8.9E-82 T 26-04-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 SUPERFAMILY SSF52374 374 470 3.73E-17 T 26-04-2017 A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 Gene3D G3DSA:2.40.240.10 481 602 1.0E-41 T 26-04-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 Gene3D G3DSA:3.40.50.620 243 276 2.6E-37 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 Gene3D G3DSA:3.40.50.620 54 123 2.6E-37 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 Gene3D G3DSA:1.10.1160.10 393 471 2.6E-33 T 26-04-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 SUPERFAMILY SSF52374 54 276 3.0E-72 T 26-04-2017 A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 SUPERFAMILY SSF50715 473 690 2.46E-63 T 26-04-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 Gene3D G3DSA:3.90.800.10 132 240 1.4E-44 T 26-04-2017 A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 473 670 1.0E-51 T 26-04-2017 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4V04_RS00715 ff4375b984e8ce44a2069786b192cbda 694 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 61 72 - T 26-04-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS12280 6733a300f89677a1e360e1994a79ce8b 201 Pfam PF00677 Lumazine binding domain 98 186 1.1E-18 T 26-04-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS12280 6733a300f89677a1e360e1994a79ce8b 201 Pfam PF00677 Lumazine binding domain 3 84 7.9E-15 T 26-04-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS12280 6733a300f89677a1e360e1994a79ce8b 201 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 196 5.3E-56 T 26-04-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS12280 6733a300f89677a1e360e1994a79ce8b 201 Gene3D G3DSA:2.40.30.20 5 102 2.3E-26 T 26-04-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 A4V04_RS12280 6733a300f89677a1e360e1994a79ce8b 201 Gene3D G3DSA:2.40.30.20 103 196 1.6E-28 T 26-04-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 A4V04_RS12280 6733a300f89677a1e360e1994a79ce8b 201 SUPERFAMILY SSF63380 91 197 3.57E-28 T 26-04-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A4V04_RS12280 6733a300f89677a1e360e1994a79ce8b 201 SUPERFAMILY SSF63380 1 91 3.32E-21 T 26-04-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A4V04_RS12280 6733a300f89677a1e360e1994a79ce8b 201 PIRSF PIRSF000498 1 200 1.6E-67 T 26-04-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS04810 529390cac758eeec64e42857d6894c76 368 SUPERFAMILY SSF102114 30 315 4.05E-76 T 26-04-2017 A4V04_RS04810 529390cac758eeec64e42857d6894c76 368 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 29 368 40.808 T 26-04-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS04810 529390cac758eeec64e42857d6894c76 368 Pfam PF13353 4Fe-4S single cluster domain 45 155 6.4E-9 T 26-04-2017 A4V04_RS04810 529390cac758eeec64e42857d6894c76 368 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 44 55 - T 26-04-2017 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS04810 529390cac758eeec64e42857d6894c76 368 SMART SM00729 38 251 4.9E-10 T 26-04-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4V04_RS04810 529390cac758eeec64e42857d6894c76 368 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 30 368 7.7E-117 T 26-04-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS04810 529390cac758eeec64e42857d6894c76 368 Pfam PF06463 Molybdenum Cofactor Synthesis C 219 345 1.6E-37 T 26-04-2017 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS04810 529390cac758eeec64e42857d6894c76 368 Gene3D G3DSA:3.20.20.70 29 333 5.0E-81 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS04810 529390cac758eeec64e42857d6894c76 368 Pfam PF04055 Radical SAM superfamily 42 212 6.0E-30 T 26-04-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 A4V04_RS11535 cf5d2dc3ba6ee08eb31f0454bd36c315 208 Gene3D G3DSA:1.10.10.10 146 191 7.5E-20 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS11535 cf5d2dc3ba6ee08eb31f0454bd36c315 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 9.0E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS11535 cf5d2dc3ba6ee08eb31f0454bd36c315 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 9.0E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS11535 cf5d2dc3ba6ee08eb31f0454bd36c315 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 9.0E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS11535 cf5d2dc3ba6ee08eb31f0454bd36c315 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 155 182 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS11535 cf5d2dc3ba6ee08eb31f0454bd36c315 208 SMART SM00421 138 195 1.9E-14 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS11535 cf5d2dc3ba6ee08eb31f0454bd36c315 208 Pfam PF00072 Response regulator receiver domain 6 114 1.2E-23 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS11535 cf5d2dc3ba6ee08eb31f0454bd36c315 208 SUPERFAMILY SSF46894 130 192 7.48E-18 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS11535 cf5d2dc3ba6ee08eb31f0454bd36c315 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 191 4.0E-16 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS11535 cf5d2dc3ba6ee08eb31f0454bd36c315 208 SUPERFAMILY SSF52172 3 144 4.13E-33 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS11535 cf5d2dc3ba6ee08eb31f0454bd36c315 208 Gene3D G3DSA:3.40.50.2300 2 145 4.3E-29 T 26-04-2017 A4V04_RS11535 cf5d2dc3ba6ee08eb31f0454bd36c315 208 SMART SM00448 3 114 2.7E-27 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS05650 6ab0167417110ec7440176e3222aea93 332 Gene3D G3DSA:3.20.20.70 94 307 1.1E-11 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS05650 6ab0167417110ec7440176e3222aea93 332 PIRSF PIRSF006004 1 332 5.7E-80 T 26-04-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS05650 6ab0167417110ec7440176e3222aea93 332 SUPERFAMILY SSF102114 91 299 2.88E-13 T 26-04-2017 A4V04_RS05650 6ab0167417110ec7440176e3222aea93 332 Pfam PF04055 Radical SAM superfamily 96 255 5.3E-12 T 26-04-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 A4V04_RS04375 b408e56c55f4f40d8bfbb0707caf8bd6 172 Gene3D G3DSA:3.90.1720.10 51 171 2.5E-37 T 26-04-2017 IPR000064 Endopeptidase, NLPC/P60 domain A4V04_RS04375 b408e56c55f4f40d8bfbb0707caf8bd6 172 SUPERFAMILY SSF54001 49 171 1.03E-34 T 26-04-2017 A4V04_RS04375 b408e56c55f4f40d8bfbb0707caf8bd6 172 Pfam PF00877 NlpC/P60 family 65 169 6.4E-23 T 26-04-2017 IPR000064 Endopeptidase, NLPC/P60 domain A4V04_RS02975 7cbe9d286a607515cf5a5b4cb4b7339f 469 Gene3D G3DSA:3.50.50.60 417 466 9.2E-47 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02975 7cbe9d286a607515cf5a5b4cb4b7339f 469 Gene3D G3DSA:3.50.50.60 22 267 9.2E-47 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02975 7cbe9d286a607515cf5a5b4cb4b7339f 469 SUPERFAMILY SSF56425 287 421 1.24E-35 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02975 7cbe9d286a607515cf5a5b4cb4b7339f 469 Gene3D G3DSA:3.90.700.10 286 412 9.2E-36 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02975 7cbe9d286a607515cf5a5b4cb4b7339f 469 SUPERFAMILY SSF51905 22 277 2.44E-34 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02975 7cbe9d286a607515cf5a5b4cb4b7339f 469 SUPERFAMILY SSF51905 420 468 2.44E-34 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02975 7cbe9d286a607515cf5a5b4cb4b7339f 469 Pfam PF00890 FAD binding domain 30 450 2.3E-50 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04730 5322d0e84a785f1733cd96edaf88158c 447 Gene3D G3DSA:3.90.1260.10 176 372 2.4E-66 T 26-04-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS04730 5322d0e84a785f1733cd96edaf88158c 447 Gene3D G3DSA:1.10.287.400 377 433 6.7E-30 T 26-04-2017 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4V04_RS04730 5322d0e84a785f1733cd96edaf88158c 447 Pfam PF00764 Arginosuccinate synthase 16 406 1.1E-62 T 26-04-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS04730 5322d0e84a785f1733cd96edaf88158c 447 Gene3D G3DSA:3.40.50.620 4 175 4.8E-42 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS04730 5322d0e84a785f1733cd96edaf88158c 447 SUPERFAMILY SSF52402 5 187 1.53E-31 T 26-04-2017 A4V04_RS04730 5322d0e84a785f1733cd96edaf88158c 447 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 419 3.1E-159 T 26-04-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS04730 5322d0e84a785f1733cd96edaf88158c 447 SUPERFAMILY SSF69864 190 436 1.83E-79 T 26-04-2017 A4V04_RS04730 5322d0e84a785f1733cd96edaf88158c 447 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 26-04-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS04730 5322d0e84a785f1733cd96edaf88158c 447 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 447 68.77 T 26-04-2017 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4V04_RS04730 5322d0e84a785f1733cd96edaf88158c 447 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 26-04-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 Gene3D G3DSA:3.30.300.10 266 391 2.7E-69 T 26-04-2017 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 391 54.638 T 26-04-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 Pfam PF02772 S-adenosylmethionine synthetase, central domain 119 239 4.0E-42 T 26-04-2017 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 SUPERFAMILY SSF55973 241 392 5.3E-68 T 26-04-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 390 4.2E-173 T 26-04-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 PIRSF PIRSF000497 1 392 1.1E-166 T 26-04-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 120 130 - T 26-04-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 Gene3D G3DSA:3.30.300.10 140 239 3.9E-36 T 26-04-2017 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 SUPERFAMILY SSF55973 115 240 1.26E-43 T 26-04-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 267 275 - T 26-04-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 SUPERFAMILY SSF55973 5 111 3.06E-45 T 26-04-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 1.5E-40 T 26-04-2017 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 Gene3D G3DSA:3.30.300.10 240 265 4.7E-22 T 26-04-2017 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 Gene3D G3DSA:3.30.300.10 13 139 4.2E-46 T 26-04-2017 A4V04_RS09295 62c0c4e73cc05e81e9ea555ca65dc5bd 395 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 241 380 7.2E-69 T 26-04-2017 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4V04_RS04575 8db91e9a9c620c7ac223e16f5ccff991 240 SUPERFAMILY SSF64288 56 234 5.42E-18 T 26-04-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4V04_RS04575 8db91e9a9c620c7ac223e16f5ccff991 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 8.2E-8 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS04575 8db91e9a9c620c7ac223e16f5ccff991 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 8.2E-8 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS04575 8db91e9a9c620c7ac223e16f5ccff991 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 68 1.2E-14 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS04575 8db91e9a9c620c7ac223e16f5ccff991 240 SMART SM00866 86 231 2.6E-11 T 26-04-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4V04_RS04575 8db91e9a9c620c7ac223e16f5ccff991 240 SUPERFAMILY SSF46785 6 72 1.02E-15 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04575 8db91e9a9c620c7ac223e16f5ccff991 240 Pfam PF07702 UTRA domain 104 230 7.9E-12 T 26-04-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4V04_RS04575 8db91e9a9c620c7ac223e16f5ccff991 240 Gene3D G3DSA:3.40.1410.10 93 233 1.9E-19 T 26-04-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4V04_RS04575 8db91e9a9c620c7ac223e16f5ccff991 240 SMART SM00345 9 68 5.1E-13 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS04575 8db91e9a9c620c7ac223e16f5ccff991 240 Gene3D G3DSA:1.10.10.10 5 70 7.3E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS11905 985ef87cffd2323d213b659986382922 320 Gene3D G3DSA:1.10.10.10 14 91 1.1E-13 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS11905 985ef87cffd2323d213b659986382922 320 SUPERFAMILY SSF46785 10 119 5.16E-13 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS11905 985ef87cffd2323d213b659986382922 320 SUPERFAMILY SSF53850 95 299 3.08E-27 T 26-04-2017 A4V04_RS11905 985ef87cffd2323d213b659986382922 320 Pfam PF03466 LysR substrate binding domain 99 296 3.5E-21 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS11905 985ef87cffd2323d213b659986382922 320 Gene3D G3DSA:3.40.190.10 183 268 3.7E-14 T 26-04-2017 A4V04_RS11905 985ef87cffd2323d213b659986382922 320 Gene3D G3DSA:3.40.190.10 100 182 9.1E-16 T 26-04-2017 A4V04_RS11905 985ef87cffd2323d213b659986382922 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 69 8.5E-12 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS01340 6441c6f02fa9ae1b4b0bcee3b59137db 317 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 160 212 4.9E-10 T 26-04-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A4V04_RS01340 6441c6f02fa9ae1b4b0bcee3b59137db 317 SUPERFAMILY SSF51735 12 185 7.88E-22 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01340 6441c6f02fa9ae1b4b0bcee3b59137db 317 Gene3D G3DSA:3.40.50.720 8 210 9.1E-28 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01340 6441c6f02fa9ae1b4b0bcee3b59137db 317 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 131 1.8E-13 T 26-04-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4V04_RS11055 896b8a626c493cfdef215e44113e4b51 257 Gene3D G3DSA:3.40.50.720 4 243 1.9E-57 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS11055 896b8a626c493cfdef215e44113e4b51 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 9.9E-24 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS11055 896b8a626c493cfdef215e44113e4b51 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 9.9E-24 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS11055 896b8a626c493cfdef215e44113e4b51 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 9.9E-24 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS11055 896b8a626c493cfdef215e44113e4b51 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 9.9E-24 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS11055 896b8a626c493cfdef215e44113e4b51 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 9.9E-24 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS11055 896b8a626c493cfdef215e44113e4b51 257 SUPERFAMILY SSF51735 3 244 2.03E-59 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS11055 896b8a626c493cfdef215e44113e4b51 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.2E-6 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS11055 896b8a626c493cfdef215e44113e4b51 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.2E-6 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS11055 896b8a626c493cfdef215e44113e4b51 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.2E-6 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS11055 896b8a626c493cfdef215e44113e4b51 257 Pfam PF00106 short chain dehydrogenase 3 190 1.8E-45 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS11055 896b8a626c493cfdef215e44113e4b51 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 26-04-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4V04_RS11615 a59237ddc5fbc621271ce4c4884fed1e 139 Pfam PF02472 Biopolymer transport protein ExbD/TolR 8 133 4.2E-26 T 26-04-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 A4V04_RS04745 f99e11e4f77cc130e95f8b183bf99345 187 Gene3D G3DSA:3.40.50.2300 3 130 8.2E-30 T 26-04-2017 A4V04_RS04745 f99e11e4f77cc130e95f8b183bf99345 187 SUPERFAMILY SSF52172 3 131 5.12E-30 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS04745 f99e11e4f77cc130e95f8b183bf99345 187 SUPERFAMILY SSF46894 117 182 1.09E-14 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS04745 f99e11e4f77cc130e95f8b183bf99345 187 Pfam PF00072 Response regulator receiver domain 2 101 3.3E-22 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS04745 f99e11e4f77cc130e95f8b183bf99345 187 SMART SM00421 125 182 2.4E-13 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS04745 f99e11e4f77cc130e95f8b183bf99345 187 SMART SM00448 1 101 2.0E-14 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS04745 f99e11e4f77cc130e95f8b183bf99345 187 Pfam PF00196 Bacterial regulatory proteins, luxR family 126 178 7.3E-15 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS04745 f99e11e4f77cc130e95f8b183bf99345 187 Gene3D G3DSA:1.10.10.10 131 180 2.3E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04745 f99e11e4f77cc130e95f8b183bf99345 187 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 158 4.0E-10 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS04745 f99e11e4f77cc130e95f8b183bf99345 187 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 128 142 4.0E-10 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS04745 f99e11e4f77cc130e95f8b183bf99345 187 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 170 4.0E-10 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS12565 09aa224729e3cd1d0ff1295af94fae23 268 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 160 15.29 T 26-04-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 A4V04_RS12565 09aa224729e3cd1d0ff1295af94fae23 268 Pfam PF02416 mttA/Hcf106 family 5 40 1.9E-7 T 26-04-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A4V04_RS12565 09aa224729e3cd1d0ff1295af94fae23 268 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 7.7E-11 T 26-04-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A4V04_RS12565 09aa224729e3cd1d0ff1295af94fae23 268 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 7.7E-11 T 26-04-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A4V04_RS12565 09aa224729e3cd1d0ff1295af94fae23 268 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 7.7E-11 T 26-04-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A4V04_RS09750 5033c264c43df6a420dc415d021947b2 357 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS09750 5033c264c43df6a420dc415d021947b2 357 SUPERFAMILY SSF48557 18 356 1.88E-37 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS09750 5033c264c43df6a420dc415d021947b2 357 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 2.2E-6 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09750 5033c264c43df6a420dc415d021947b2 357 PRINTS PR00149 Fumarate lyase superfamily signature 231 258 2.2E-6 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09750 5033c264c43df6a420dc415d021947b2 357 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 2.2E-6 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09750 5033c264c43df6a420dc415d021947b2 357 Gene3D G3DSA:1.20.200.10 103 356 2.8E-38 T 26-04-2017 A4V04_RS09750 5033c264c43df6a420dc415d021947b2 357 Pfam PF00206 Lyase 23 300 3.3E-26 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS03165 13d2c21747a6386e99efe045e5e0ee94 398 SUPERFAMILY SSF51690 118 389 2.35E-83 T 26-04-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A4V04_RS03165 13d2c21747a6386e99efe045e5e0ee94 398 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 166 390 1.6E-70 T 26-04-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A4V04_RS03165 13d2c21747a6386e99efe045e5e0ee94 398 SUPERFAMILY SSF54675 1 134 4.94E-39 T 26-04-2017 A4V04_RS03165 13d2c21747a6386e99efe045e5e0ee94 398 PIRSF PIRSF000484 1 396 1.4E-69 T 26-04-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A4V04_RS03165 13d2c21747a6386e99efe045e5e0ee94 398 Gene3D G3DSA:3.20.140.10 2 390 3.2E-138 T 26-04-2017 A4V04_RS03165 13d2c21747a6386e99efe045e5e0ee94 398 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 1 392 44.637 T 26-04-2017 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A4V04_RS03165 13d2c21747a6386e99efe045e5e0ee94 398 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 2 390 1.1E-136 T 26-04-2017 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A4V04_RS12470 2b54f79931ffeaf7cc6ed94f26b2a383 593 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 31 270 8.1E-23 T 26-04-2017 A4V04_RS12470 2b54f79931ffeaf7cc6ed94f26b2a383 593 SUPERFAMILY SSF53850 92 251 2.29E-14 T 26-04-2017 A4V04_RS12470 2b54f79931ffeaf7cc6ed94f26b2a383 593 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 479 582 3.9E-12 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS12470 2b54f79931ffeaf7cc6ed94f26b2a383 593 Gene3D G3DSA:1.10.287.130 361 433 2.3E-5 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS12470 2b54f79931ffeaf7cc6ed94f26b2a383 593 Gene3D G3DSA:3.30.565.10 440 581 2.7E-26 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS12470 2b54f79931ffeaf7cc6ed94f26b2a383 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 564 1.1E-6 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS12470 2b54f79931ffeaf7cc6ed94f26b2a383 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 531 1.1E-6 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS12470 2b54f79931ffeaf7cc6ed94f26b2a383 593 SMART SM00388 367 437 0.0024 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS12470 2b54f79931ffeaf7cc6ed94f26b2a383 593 SUPERFAMILY SSF47384 356 434 1.2E-7 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS12470 2b54f79931ffeaf7cc6ed94f26b2a383 593 Gene3D G3DSA:3.40.190.10 120 240 2.1E-5 T 26-04-2017 A4V04_RS12470 2b54f79931ffeaf7cc6ed94f26b2a383 593 SUPERFAMILY SSF55874 423 582 8.25E-26 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS12470 2b54f79931ffeaf7cc6ed94f26b2a383 593 SMART SM00387 478 586 2.5E-16 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 Gene3D G3DSA:1.10.3370.10 10 431 5.4E-169 T 26-04-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 PIRSF PIRSF004557 3 434 1.9E-129 T 26-04-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 18 423 1.7E-133 T 26-04-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 Pfam PF00344 SecY translocase 73 411 1.0E-120 T 26-04-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 Hamap MF_01465 Protein translocase subunit SecY [secY]. 7 427 30.107 T 26-04-2017 IPR026593 Protein translocase subunit SecY A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 266 285 7.0E-94 T 26-04-2017 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 364 382 7.0E-94 T 26-04-2017 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 174 197 7.0E-94 T 26-04-2017 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 7.0E-94 T 26-04-2017 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 7.0E-94 T 26-04-2017 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 396 414 7.0E-94 T 26-04-2017 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 20 38 7.0E-94 T 26-04-2017 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 148 173 7.0E-94 T 26-04-2017 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 309 331 7.0E-94 T 26-04-2017 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 ProSitePatterns PS00756 Protein secY signature 2. 167 184 - T 26-04-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 SUPERFAMILY SSF103491 11 418 3.92E-134 T 26-04-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4V04_RS11325 a8b08fc1915df17bea1a554a2af854d2 442 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 26-04-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4V04_RS07465 084b3b9371c5d5f36fc6e92449cfbb1e 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 453 468 1.7E-8 T 26-04-2017 A4V04_RS07465 084b3b9371c5d5f36fc6e92449cfbb1e 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 28 50 1.7E-8 T 26-04-2017 A4V04_RS07465 084b3b9371c5d5f36fc6e92449cfbb1e 503 Gene3D G3DSA:3.50.50.60 433 499 4.1E-66 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07465 084b3b9371c5d5f36fc6e92449cfbb1e 503 Gene3D G3DSA:3.50.50.60 21 252 4.1E-66 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07465 084b3b9371c5d5f36fc6e92449cfbb1e 503 SUPERFAMILY SSF51905 436 497 1.12E-42 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07465 084b3b9371c5d5f36fc6e92449cfbb1e 503 SUPERFAMILY SSF51905 17 258 1.12E-42 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07465 084b3b9371c5d5f36fc6e92449cfbb1e 503 SUPERFAMILY SSF56425 279 425 1.5E-18 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS07465 084b3b9371c5d5f36fc6e92449cfbb1e 503 Gene3D G3DSA:3.90.700.10 281 425 3.5E-23 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS07465 084b3b9371c5d5f36fc6e92449cfbb1e 503 Pfam PF00890 FAD binding domain 28 470 2.0E-50 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS06350 ab6f9f86673c8270e6408324f28915ed 232 SUPERFAMILY SSF53955 47 85 2.06E-15 T 26-04-2017 IPR023346 Lysozyme-like domain A4V04_RS06350 ab6f9f86673c8270e6408324f28915ed 232 SUPERFAMILY SSF53955 112 192 2.06E-15 T 26-04-2017 IPR023346 Lysozyme-like domain A4V04_RS06350 ab6f9f86673c8270e6408324f28915ed 232 Pfam PF01464 Transglycosylase SLT domain 54 190 1.2E-15 T 26-04-2017 IPR008258 Transglycosylase SLT domain 1 A4V04_RS06350 ab6f9f86673c8270e6408324f28915ed 232 Gene3D G3DSA:1.10.530.10 63 176 1.5E-9 T 26-04-2017 A4V04_RS05750 daf57aa5a07e6fc5c0cceb59f35ed909 580 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 14 574 3.4E-246 T 26-04-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A4V04_RS05750 daf57aa5a07e6fc5c0cceb59f35ed909 580 SUPERFAMILY SSF52467 196 369 7.48E-60 T 26-04-2017 IPR029035 DHS-like NAD/FAD-binding domain A4V04_RS05750 daf57aa5a07e6fc5c0cceb59f35ed909 580 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 203 337 6.8E-44 T 26-04-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4V04_RS05750 daf57aa5a07e6fc5c0cceb59f35ed909 580 Gene3D G3DSA:3.40.50.970 13 189 1.3E-73 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS05750 daf57aa5a07e6fc5c0cceb59f35ed909 580 Gene3D G3DSA:3.40.50.1220 200 361 6.3E-61 T 26-04-2017 IPR029035 DHS-like NAD/FAD-binding domain A4V04_RS05750 daf57aa5a07e6fc5c0cceb59f35ed909 580 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 402 551 5.6E-50 T 26-04-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4V04_RS05750 daf57aa5a07e6fc5c0cceb59f35ed909 580 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 14 180 9.4E-60 T 26-04-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4V04_RS05750 daf57aa5a07e6fc5c0cceb59f35ed909 580 SUPERFAMILY SSF52518 12 192 4.12E-63 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS05750 daf57aa5a07e6fc5c0cceb59f35ed909 580 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 439 458 - T 26-04-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A4V04_RS05750 daf57aa5a07e6fc5c0cceb59f35ed909 580 SUPERFAMILY SSF52518 380 576 2.5E-71 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS05750 daf57aa5a07e6fc5c0cceb59f35ed909 580 Gene3D G3DSA:3.40.50.970 362 568 1.0E-79 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS09045 45015870937010b1292326c0b85cb575 340 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 196 212 - T 26-04-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4V04_RS09045 45015870937010b1292326c0b85cb575 340 SMART SM00478 43 194 3.5E-40 T 26-04-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4V04_RS09045 45015870937010b1292326c0b85cb575 340 SUPERFAMILY SSF48150 13 229 4.4E-70 T 26-04-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4V04_RS09045 45015870937010b1292326c0b85cb575 340 SMART SM00525 195 215 5.9E-4 T 26-04-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A4V04_RS09045 45015870937010b1292326c0b85cb575 340 Gene3D G3DSA:1.10.1670.10 127 229 1.7E-35 T 26-04-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A4V04_RS09045 45015870937010b1292326c0b85cb575 340 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 40 158 1.8E-19 T 26-04-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4V04_RS09045 45015870937010b1292326c0b85cb575 340 Gene3D G3DSA:3.90.79.10 233 329 8.4E-12 T 26-04-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4V04_RS09045 45015870937010b1292326c0b85cb575 340 SUPERFAMILY SSF55811 224 329 6.24E-18 T 26-04-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4V04_RS09045 45015870937010b1292326c0b85cb575 340 Pfam PF14815 NUDIX domain 239 329 1.9E-17 T 26-04-2017 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4V04_RS09045 45015870937010b1292326c0b85cb575 340 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 13 269 1.1E-99 T 26-04-2017 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 A4V04_RS09045 45015870937010b1292326c0b85cb575 340 Gene3D G3DSA:1.10.340.30 26 126 4.7E-43 T 26-04-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4V04_RS09045 45015870937010b1292326c0b85cb575 340 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 196 212 4.6E-4 T 26-04-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 3.6E-35 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 3.6E-35 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 3.6E-35 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 3.6E-35 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 Gene3D G3DSA:3.40.50.300 156 340 6.2E-53 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 26-04-2017 IPR006074 GTP1/OBG, conserved site GO:0005525 A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 SUPERFAMILY SSF82051 2 158 1.7E-57 T 26-04-2017 IPR006169 GTP1/OBG domain GO:0005525 A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 Hamap MF_01454 GTPase Obg [obg]. 2 334 48.577 T 26-04-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 161 329 9.2E-14 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 Gene3D G3DSA:2.70.210.12 2 155 1.2E-60 T 26-04-2017 IPR006169 GTP1/OBG domain GO:0005525 A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 333 1.6E-145 T 26-04-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 PIRSF PIRSF002401 1 366 9.1E-140 T 26-04-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 Pfam PF01926 50S ribosome-binding GTPase 161 285 3.8E-23 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 SUPERFAMILY SSF52540 151 338 2.68E-53 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11665 38c3f23ae169633d4ad83e81263da275 367 Pfam PF01018 GTP1/OBG 3 158 1.1E-62 T 26-04-2017 IPR006169 GTP1/OBG domain GO:0005525 A4V04_RS05800 69eae3683f2265d8eacd27695765aef2 388 Gene3D G3DSA:3.40.50.1970 1 185 1.2E-52 T 26-04-2017 A4V04_RS05800 69eae3683f2265d8eacd27695765aef2 388 SUPERFAMILY SSF56796 1 385 2.88E-97 T 26-04-2017 A4V04_RS05800 69eae3683f2265d8eacd27695765aef2 388 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 380 3.4E-90 T 26-04-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A4V04_RS05800 69eae3683f2265d8eacd27695765aef2 388 Gene3D G3DSA:1.20.1090.10 186 385 1.5E-52 T 26-04-2017 A4V04_RS09800 41f3f9e76f5534ddc76f655b67b6774b 305 Pfam PF04085 rod shape-determining protein MreC 135 275 5.1E-31 T 26-04-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 A4V04_RS09800 41f3f9e76f5534ddc76f655b67b6774b 305 PIRSF PIRSF038471 8 290 1.6E-59 T 26-04-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 A4V04_RS09800 41f3f9e76f5534ddc76f655b67b6774b 305 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 25 277 6.0E-34 T 26-04-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 A4V04_RS10680 4452b35e5a3116d938358960943e1826 467 Gene3D G3DSA:1.10.1140.10 352 466 5.9E-55 T 26-04-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4V04_RS10680 4452b35e5a3116d938358960943e1826 467 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 26-04-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4V04_RS10680 4452b35e5a3116d938358960943e1826 467 Gene3D G3DSA:2.40.10.170 2 80 1.6E-28 T 26-04-2017 A4V04_RS10680 4452b35e5a3116d938358960943e1826 467 SUPERFAMILY SSF52540 83 353 1.04E-89 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10680 4452b35e5a3116d938358960943e1826 467 SUPERFAMILY SSF47917 351 466 6.54E-54 T 26-04-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4V04_RS10680 4452b35e5a3116d938358960943e1826 467 Gene3D G3DSA:3.40.50.300 83 349 2.3E-107 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10680 4452b35e5a3116d938358960943e1826 467 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 136 348 1.6E-63 T 26-04-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4V04_RS10680 4452b35e5a3116d938358960943e1826 467 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 79 3.1E-19 T 26-04-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4V04_RS10680 4452b35e5a3116d938358960943e1826 467 SUPERFAMILY SSF50615 2 79 3.14E-23 T 26-04-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4V04_RS10680 4452b35e5a3116d938358960943e1826 467 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 466 55.995 T 26-04-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 A4V04_RS10680 4452b35e5a3116d938358960943e1826 467 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 466 2.4E-248 T 26-04-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 A4V04_RS10680 4452b35e5a3116d938358960943e1826 467 SMART SM00382 148 333 3.6E-4 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS02565 3a8322216f69eef47fab7932b8ae60a1 248 Pfam PF00872 Transposase, Mutator family 36 207 2.5E-41 T 26-04-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4V04_RS13145 5ff23dab34369b2542bba17ada92a2c3 460 Gene3D G3DSA:1.20.120.140 2 88 6.0E-32 T 26-04-2017 A4V04_RS13145 5ff23dab34369b2542bba17ada92a2c3 460 Gene3D G3DSA:3.40.50.300 98 301 8.4E-73 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13145 5ff23dab34369b2542bba17ada92a2c3 460 SUPERFAMILY SSF52540 42 361 1.21E-48 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13145 5ff23dab34369b2542bba17ada92a2c3 460 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 273 286 - T 26-04-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4V04_RS13145 5ff23dab34369b2542bba17ada92a2c3 460 SMART SM00963 1 86 4.8E-31 T 26-04-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4V04_RS13145 5ff23dab34369b2542bba17ada92a2c3 460 SMART SM00382 103 251 7.7E-10 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS13145 5ff23dab34369b2542bba17ada92a2c3 460 Pfam PF00448 SRP54-type protein, GTPase domain 104 300 9.7E-70 T 26-04-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4V04_RS13145 5ff23dab34369b2542bba17ada92a2c3 460 Pfam PF02978 Signal peptide binding domain 333 432 1.4E-31 T 26-04-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A4V04_RS13145 5ff23dab34369b2542bba17ada92a2c3 460 Gene3D G3DSA:1.10.260.30 333 437 6.0E-36 T 26-04-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A4V04_RS13145 5ff23dab34369b2542bba17ada92a2c3 460 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 444 33.069 T 26-04-2017 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 A4V04_RS13145 5ff23dab34369b2542bba17ada92a2c3 460 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.1E-19 T 26-04-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4V04_RS13145 5ff23dab34369b2542bba17ada92a2c3 460 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 434 1.2E-168 T 26-04-2017 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 A4V04_RS13145 5ff23dab34369b2542bba17ada92a2c3 460 SMART SM00962 104 300 1.1E-107 T 26-04-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4V04_RS13145 5ff23dab34369b2542bba17ada92a2c3 460 SUPERFAMILY SSF47446 333 436 2.45E-32 T 26-04-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A4V04_RS03000 adf6126c3878ee3bc9c69fbd4e640128 673 SMART SM00491 496 630 7.9E-37 T 26-04-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A4V04_RS03000 adf6126c3878ee3bc9c69fbd4e640128 673 SUPERFAMILY SSF52540 396 569 9.27E-12 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03000 adf6126c3878ee3bc9c69fbd4e640128 673 SUPERFAMILY SSF52540 600 622 9.27E-12 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03000 adf6126c3878ee3bc9c69fbd4e640128 673 SUPERFAMILY SSF52540 196 236 9.27E-12 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03000 adf6126c3878ee3bc9c69fbd4e640128 673 Pfam PF04851 Type III restriction enzyme, res subunit 27 241 5.0E-6 T 26-04-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4V04_RS03000 adf6126c3878ee3bc9c69fbd4e640128 673 Gene3D G3DSA:3.40.50.300 412 425 8.0E-21 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03000 adf6126c3878ee3bc9c69fbd4e640128 673 Gene3D G3DSA:3.40.50.300 26 125 8.0E-21 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03000 adf6126c3878ee3bc9c69fbd4e640128 673 Gene3D G3DSA:3.40.50.300 196 261 8.0E-21 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03000 adf6126c3878ee3bc9c69fbd4e640128 673 Pfam PF13307 Helicase C-terminal domain 481 642 1.7E-36 T 26-04-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A4V04_RS03000 adf6126c3878ee3bc9c69fbd4e640128 673 SUPERFAMILY SSF52540 24 240 6.12E-23 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03000 adf6126c3878ee3bc9c69fbd4e640128 673 SMART SM00487 24 280 3.0E-4 T 26-04-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4V04_RS03000 adf6126c3878ee3bc9c69fbd4e640128 673 Gene3D G3DSA:3.40.50.300 482 623 1.1E-5 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 Pfam PF00873 AcrB/AcrD/AcrF family 3 1020 0.0 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 SUPERFAMILY SSF82866 801 1026 1.96E-45 T 26-04-2017 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 SUPERFAMILY SSF82714 185 273 1.7E-19 T 26-04-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 SUPERFAMILY SSF82866 298 499 1.19E-48 T 26-04-2017 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 SUPERFAMILY SSF82693 39 133 4.45E-22 T 26-04-2017 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 Gene3D G3DSA:3.30.2090.10 717 803 4.2E-23 T 26-04-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 SUPERFAMILY SSF82693 563 666 1.67E-17 T 26-04-2017 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 Gene3D G3DSA:3.30.70.1430 565 666 1.9E-16 T 26-04-2017 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 SUPERFAMILY SSF82693 138 183 9.77E-25 T 26-04-2017 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 SUPERFAMILY SSF82693 276 332 9.77E-25 T 26-04-2017 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 2 1021 0.0 T 26-04-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 Gene3D G3DSA:1.10.3850.10 281 501 1.1E-59 T 26-04-2017 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 Gene3D G3DSA:1.10.3850.10 809 1023 4.2E-58 T 26-04-2017 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 SUPERFAMILY SSF82714 717 803 3.53E-20 T 26-04-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 Gene3D G3DSA:3.30.70.1430 39 141 3.2E-27 T 26-04-2017 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 Gene3D G3DSA:3.30.2090.10 183 276 7.1E-24 T 26-04-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 PRINTS PR00702 Acriflavin resistance protein family signature 550 567 8.5E-91 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 8.5E-91 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 8.5E-91 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 PRINTS PR00702 Acriflavin resistance protein family signature 619 633 8.5E-91 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 8.5E-91 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 8.5E-91 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 8.5E-91 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 8.5E-91 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08085 cea65f274ff099eafd7259f6a5677312 1031 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 8.5E-91 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS02410 f29b875b5f2be13db5fa6e5bc5ad583a 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 434 456 1.8E-6 T 26-04-2017 A4V04_RS02410 f29b875b5f2be13db5fa6e5bc5ad583a 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 34 53 1.8E-6 T 26-04-2017 A4V04_RS02410 f29b875b5f2be13db5fa6e5bc5ad583a 490 Gene3D G3DSA:3.90.700.10 303 421 2.6E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02410 f29b875b5f2be13db5fa6e5bc5ad583a 490 SUPERFAMILY SSF56425 303 422 3.14E-24 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02410 f29b875b5f2be13db5fa6e5bc5ad583a 490 SUPERFAMILY SSF51905 26 278 1.2E-44 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02410 f29b875b5f2be13db5fa6e5bc5ad583a 490 SUPERFAMILY SSF51905 429 489 1.2E-44 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02410 f29b875b5f2be13db5fa6e5bc5ad583a 490 Pfam PF00890 FAD binding domain 34 462 1.3E-59 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02410 f29b875b5f2be13db5fa6e5bc5ad583a 490 Gene3D G3DSA:3.50.50.60 426 489 3.1E-71 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02410 f29b875b5f2be13db5fa6e5bc5ad583a 490 Gene3D G3DSA:3.50.50.60 29 275 3.1E-71 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04035 06d3a2d4745cbea640217b6366c93817 366 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 5 345 3.0E-123 T 26-04-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4V04_RS04035 06d3a2d4745cbea640217b6366c93817 366 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 82 101 - T 26-04-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A4V04_RS04035 06d3a2d4745cbea640217b6366c93817 366 Pfam PF01180 Dihydroorotate dehydrogenase 50 344 2.5E-87 T 26-04-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A4V04_RS04035 06d3a2d4745cbea640217b6366c93817 366 Gene3D G3DSA:3.20.20.70 2 351 1.0E-120 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS04035 06d3a2d4745cbea640217b6366c93817 366 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 299 319 - T 26-04-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A4V04_RS04035 06d3a2d4745cbea640217b6366c93817 366 SUPERFAMILY SSF51395 5 350 2.0E-93 T 26-04-2017 A4V04_RS04035 06d3a2d4745cbea640217b6366c93817 366 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 4 343 46.318 T 26-04-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4V04_RS09235 20c0ede8e2a6ff7aef27a589c6af15e8 605 Gene3D G3DSA:3.40.190.10 118 206 7.4E-10 T 26-04-2017 A4V04_RS09235 20c0ede8e2a6ff7aef27a589c6af15e8 605 SUPERFAMILY SSF55874 420 589 1.11E-24 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS09235 20c0ede8e2a6ff7aef27a589c6af15e8 605 SUPERFAMILY SSF47384 358 430 1.73E-7 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS09235 20c0ede8e2a6ff7aef27a589c6af15e8 605 SUPERFAMILY SSF53850 35 289 2.62E-13 T 26-04-2017 A4V04_RS09235 20c0ede8e2a6ff7aef27a589c6af15e8 605 SMART SM00387 476 587 4.5E-14 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS09235 20c0ede8e2a6ff7aef27a589c6af15e8 605 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 482 585 4.0E-12 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS09235 20c0ede8e2a6ff7aef27a589c6af15e8 605 Gene3D G3DSA:3.30.565.10 433 585 1.7E-25 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS09235 20c0ede8e2a6ff7aef27a589c6af15e8 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 531 6.1E-10 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS09235 20c0ede8e2a6ff7aef27a589c6af15e8 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 564 6.1E-10 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS09235 20c0ede8e2a6ff7aef27a589c6af15e8 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 571 584 6.1E-10 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS09235 20c0ede8e2a6ff7aef27a589c6af15e8 605 Pfam PF00512 His Kinase A (phospho-acceptor) domain 368 431 8.7E-7 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS09235 20c0ede8e2a6ff7aef27a589c6af15e8 605 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 42 261 2.0E-25 T 26-04-2017 A4V04_RS09235 20c0ede8e2a6ff7aef27a589c6af15e8 605 Gene3D G3DSA:1.10.287.130 364 430 5.2E-4 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS09235 20c0ede8e2a6ff7aef27a589c6af15e8 605 SMART SM00388 364 434 1.5E-4 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS12930 de5af650002a19096fb452bde3be77de 135 SUPERFAMILY SSF47598 1 45 3.45E-9 T 26-04-2017 IPR010985 Ribbon-helix-helix GO:0006355 A4V04_RS12930 de5af650002a19096fb452bde3be77de 135 Gene3D G3DSA:3.30.70.1150 50 131 8.2E-25 T 26-04-2017 A4V04_RS12930 de5af650002a19096fb452bde3be77de 135 Pfam PF08753 NikR C terminal nickel binding domain 53 127 8.0E-23 T 26-04-2017 IPR014864 Transcription factor, NikR, nickel binding C-terminal A4V04_RS12930 de5af650002a19096fb452bde3be77de 135 Gene3D G3DSA:1.10.1220.10 1 44 1.9E-17 T 26-04-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A4V04_RS12930 de5af650002a19096fb452bde3be77de 135 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 42 9.6E-10 T 26-04-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A4V04_RS12930 de5af650002a19096fb452bde3be77de 135 SUPERFAMILY SSF55021 51 131 1.14E-17 T 26-04-2017 A4V04_RS12930 de5af650002a19096fb452bde3be77de 135 Hamap MF_00476 Putative nickel-responsive regulator [nikR]. 1 131 23.003 T 26-04-2017 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 SMART SM00957 5 396 0.0 T 26-04-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 SMART SM00958 227 352 4.8E-76 T 26-04-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 Pfam PF01043 SecA preprotein cross-linking domain 232 352 1.1E-37 T 26-04-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 Gene3D G3DSA:3.40.50.300 412 620 4.5E-90 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 Pfam PF07516 SecA Wing and Scaffold domain 618 831 1.8E-60 T 26-04-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 Gene3D G3DSA:3.90.1440.10 230 362 1.5E-45 T 26-04-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 SUPERFAMILY SSF81767 226 362 5.23E-43 T 26-04-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 Gene3D G3DSA:3.40.50.300 2 227 3.7E-127 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 Gene3D G3DSA:3.40.50.300 363 410 3.7E-127 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 Gene3D G3DSA:1.10.3060.10 649 832 8.5E-51 T 26-04-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 Pfam PF07517 SecA DEAD-like domain 6 396 4.6E-133 T 26-04-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 ProSitePatterns PS01312 SecA family signature. 494 509 - T 26-04-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 SUPERFAMILY SSF81886 876 888 2.88E-76 T 26-04-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 SUPERFAMILY SSF81886 623 841 2.88E-76 T 26-04-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 SUPERFAMILY SSF52540 362 409 7.36E-85 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 SUPERFAMILY SSF52540 4 227 7.36E-85 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 Pfam PF02810 SEC-C motif 880 898 3.0E-10 T 26-04-2017 IPR004027 SEC-C motif A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 PRINTS PR00906 SecA protein signature 169 189 6.9E-70 T 26-04-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 PRINTS PR00906 SecA protein signature 407 420 6.9E-70 T 26-04-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 PRINTS PR00906 SecA protein signature 333 355 6.9E-70 T 26-04-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 PRINTS PR00906 SecA protein signature 116 126 6.9E-70 T 26-04-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 PRINTS PR00906 SecA protein signature 100 114 6.9E-70 T 26-04-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 PRINTS PR00906 SecA protein signature 62 86 6.9E-70 T 26-04-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 PRINTS PR00906 SecA protein signature 370 387 6.9E-70 T 26-04-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 818 0.0 T 26-04-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 SUPERFAMILY SSF52540 411 619 6.84E-56 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11965 c11957a3aef42aad3db2be6f136c0174 900 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 833 19.826 T 26-04-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4V04_RS12475 352e33308ec0685e4518b261b7efcd00 207 SMART SM00421 141 198 1.5E-16 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS12475 352e33308ec0685e4518b261b7efcd00 207 SUPERFAMILY SSF52172 10 145 1.71E-30 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS12475 352e33308ec0685e4518b261b7efcd00 207 Gene3D G3DSA:1.10.10.10 144 198 5.9E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS12475 352e33308ec0685e4518b261b7efcd00 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 143 196 8.3E-16 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS12475 352e33308ec0685e4518b261b7efcd00 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 9.9E-10 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS12475 352e33308ec0685e4518b261b7efcd00 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 9.9E-10 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS12475 352e33308ec0685e4518b261b7efcd00 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 9.9E-10 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS12475 352e33308ec0685e4518b261b7efcd00 207 SMART SM00448 6 117 6.0E-20 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS12475 352e33308ec0685e4518b261b7efcd00 207 SUPERFAMILY SSF46894 134 200 5.44E-16 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS12475 352e33308ec0685e4518b261b7efcd00 207 Gene3D G3DSA:3.40.50.2300 8 143 4.9E-29 T 26-04-2017 A4V04_RS12475 352e33308ec0685e4518b261b7efcd00 207 Pfam PF00072 Response regulator receiver domain 8 117 3.7E-22 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS07400 2ea1f328b506aa65aef41a203f24d974 140 Gene3D G3DSA:3.30.70.60 1 104 3.6E-42 T 26-04-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A4V04_RS07400 2ea1f328b506aa65aef41a203f24d974 140 Pfam PF01250 Ribosomal protein S6 3 91 2.2E-28 T 26-04-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07400 2ea1f328b506aa65aef41a203f24d974 140 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.734 T 26-04-2017 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4V04_RS07400 2ea1f328b506aa65aef41a203f24d974 140 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 1.2E-32 T 26-04-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07400 2ea1f328b506aa65aef41a203f24d974 140 SUPERFAMILY SSF54995 1 104 2.49E-38 T 26-04-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS05820 6715e92c62a7aa0999ee57c8a7944ccd 792 PIRSF PIRSF000854 1 792 0.0 T 26-04-2017 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 A4V04_RS05820 6715e92c62a7aa0999ee57c8a7944ccd 792 Gene3D G3DSA:3.30.1490.20 5 194 5.3E-69 T 26-04-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4V04_RS05820 6715e92c62a7aa0999ee57c8a7944ccd 792 Gene3D G3DSA:3.20.20.60 483 791 5.0E-107 T 26-04-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4V04_RS05820 6715e92c62a7aa0999ee57c8a7944ccd 792 Gene3D G3DSA:3.30.470.20 196 349 2.1E-59 T 26-04-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4V04_RS05820 6715e92c62a7aa0999ee57c8a7944ccd 792 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 416 427 - T 26-04-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A4V04_RS05820 6715e92c62a7aa0999ee57c8a7944ccd 792 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 484 789 2.2E-62 T 26-04-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A4V04_RS05820 6715e92c62a7aa0999ee57c8a7944ccd 792 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 792 0.0 T 26-04-2017 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 A4V04_RS05820 6715e92c62a7aa0999ee57c8a7944ccd 792 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 696 714 - T 26-04-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A4V04_RS05820 6715e92c62a7aa0999ee57c8a7944ccd 792 SUPERFAMILY SSF52009 355 469 3.4E-33 T 26-04-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4V04_RS05820 6715e92c62a7aa0999ee57c8a7944ccd 792 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 349 9.3E-122 T 26-04-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A4V04_RS05820 6715e92c62a7aa0999ee57c8a7944ccd 792 Gene3D G3DSA:3.50.30.10 377 476 2.1E-35 T 26-04-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4V04_RS05820 6715e92c62a7aa0999ee57c8a7944ccd 792 SUPERFAMILY SSF51621 467 790 1.33E-96 T 26-04-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4V04_RS05820 6715e92c62a7aa0999ee57c8a7944ccd 792 Pfam PF00391 PEP-utilising enzyme, mobile domain 386 457 1.6E-25 T 26-04-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4V04_RS05820 6715e92c62a7aa0999ee57c8a7944ccd 792 SUPERFAMILY SSF56059 5 386 5.18E-108 T 26-04-2017 A4V04_RS03735 339b77e477cfba90542ecf737d1a1b19 611 Pfam PF11893 Domain of unknown function (DUF3413) 10 245 2.2E-30 T 26-04-2017 IPR024588 Inner membrane protein YejM, N-terminal A4V04_RS03735 339b77e477cfba90542ecf737d1a1b19 611 Pfam PF00884 Sulfatase 253 528 2.6E-27 T 26-04-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 A4V04_RS03735 339b77e477cfba90542ecf737d1a1b19 611 Gene3D G3DSA:3.40.720.10 253 547 4.2E-39 T 26-04-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A4V04_RS03735 339b77e477cfba90542ecf737d1a1b19 611 PIRSF PIRSF004950 5 611 1.4E-150 T 26-04-2017 IPR012159 Inner membrane protein YejM A4V04_RS03735 339b77e477cfba90542ecf737d1a1b19 611 SUPERFAMILY SSF53649 253 565 5.82E-52 T 26-04-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A4V04_RS07450 b42f3742a5d0122d7c8e90444c8900f5 250 Gene3D G3DSA:1.10.3720.10 12 243 1.6E-50 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS07450 b42f3742a5d0122d7c8e90444c8900f5 250 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 93 4.9E-12 T 26-04-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A4V04_RS07450 b42f3742a5d0122d7c8e90444c8900f5 250 SUPERFAMILY SSF161098 13 230 7.72E-44 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS07450 b42f3742a5d0122d7c8e90444c8900f5 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 62 233 1.0E-19 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS06840 d7935f466688da8cbafb3eea0c10cf9f 116 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 114 7.7E-28 T 26-04-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 A4V04_RS06840 d7935f466688da8cbafb3eea0c10cf9f 116 PIRSF PIRSF004761 1 116 1.4E-30 T 26-04-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 A4V04_RS06840 d7935f466688da8cbafb3eea0c10cf9f 116 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 26-04-2017 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site A4V04_RS06840 d7935f466688da8cbafb3eea0c10cf9f 116 Hamap MF_00213 Probable hydrogenase nickel incorporation protein HypA [hypA]. 1 113 21.164 T 26-04-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 A4V04_RS06840 d7935f466688da8cbafb3eea0c10cf9f 116 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 111 2.8E-28 T 26-04-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 A4V04_RS02945 4d708238c7d8d96632b24fecebfdf169 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 159 320 3.2E-32 T 26-04-2017 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 A4V04_RS02945 4d708238c7d8d96632b24fecebfdf169 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 154 8.5E-32 T 26-04-2017 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 A4V04_RS02945 4d708238c7d8d96632b24fecebfdf169 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 2 321 1.3E-131 T 26-04-2017 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A4V04_RS02945 4d708238c7d8d96632b24fecebfdf169 329 SUPERFAMILY SSF56327 159 325 3.58E-57 T 26-04-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4V04_RS02945 4d708238c7d8d96632b24fecebfdf169 329 Gene3D G3DSA:3.90.110.10 157 326 8.4E-67 T 26-04-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4V04_RS02945 4d708238c7d8d96632b24fecebfdf169 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 1 326 49.713 T 26-04-2017 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A4V04_RS02945 4d708238c7d8d96632b24fecebfdf169 329 PIRSF PIRSF000102 1 328 2.0E-68 T 26-04-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A4V04_RS02945 4d708238c7d8d96632b24fecebfdf169 329 SUPERFAMILY SSF51735 3 157 3.27E-43 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS02945 4d708238c7d8d96632b24fecebfdf169 329 Gene3D G3DSA:3.40.50.720 2 155 2.1E-51 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS09315 8b0b3662b5805ef8e6e60bbd085694d8 411 SUPERFAMILY SSF88697 6 76 1.38E-17 T 26-04-2017 IPR015947 PUA-like domain A4V04_RS09315 8b0b3662b5805ef8e6e60bbd085694d8 411 Gene3D G3DSA:2.30.130.10 6 74 9.9E-25 T 26-04-2017 IPR015947 PUA-like domain A4V04_RS09315 8b0b3662b5805ef8e6e60bbd085694d8 411 SMART SM00359 6 91 2.4E-14 T 26-04-2017 IPR002478 PUA domain GO:0003723 A4V04_RS09315 8b0b3662b5805ef8e6e60bbd085694d8 411 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 171 358 1.1E-24 T 26-04-2017 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 A4V04_RS09315 8b0b3662b5805ef8e6e60bbd085694d8 411 Gene3D G3DSA:3.40.50.150 184 400 4.2E-55 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS09315 8b0b3662b5805ef8e6e60bbd085694d8 411 SUPERFAMILY SSF53335 97 400 3.23E-63 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS09315 8b0b3662b5805ef8e6e60bbd085694d8 411 Gene3D G3DSA:3.30.750.80 77 181 1.3E-31 T 26-04-2017 A4V04_RS03770 f814692844de968b15c2440d85dbc475 326 SUPERFAMILY SSF48179 175 316 1.22E-38 T 26-04-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4V04_RS03770 f814692844de968b15c2440d85dbc475 326 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 194 218 1.2E-28 T 26-04-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4V04_RS03770 f814692844de968b15c2440d85dbc475 326 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 169 193 1.2E-28 T 26-04-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4V04_RS03770 f814692844de968b15c2440d85dbc475 326 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 129 149 1.2E-28 T 26-04-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4V04_RS03770 f814692844de968b15c2440d85dbc475 326 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 1.2E-28 T 26-04-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4V04_RS03770 f814692844de968b15c2440d85dbc475 326 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 234 251 1.2E-28 T 26-04-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4V04_RS03770 f814692844de968b15c2440d85dbc475 326 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 54 81 1.2E-28 T 26-04-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4V04_RS03770 f814692844de968b15c2440d85dbc475 326 Gene3D G3DSA:3.40.50.720 1 179 2.1E-43 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03770 f814692844de968b15c2440d85dbc475 326 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 318 28.485 T 26-04-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4V04_RS03770 f814692844de968b15c2440d85dbc475 326 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 176 315 1.2E-38 T 26-04-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4V04_RS03770 f814692844de968b15c2440d85dbc475 326 PIRSF PIRSF000114 1 322 9.0E-82 T 26-04-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4V04_RS03770 f814692844de968b15c2440d85dbc475 326 Gene3D G3DSA:1.10.1040.10 180 315 5.9E-40 T 26-04-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4V04_RS03770 f814692844de968b15c2440d85dbc475 326 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 153 6.7E-35 T 26-04-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4V04_RS03770 f814692844de968b15c2440d85dbc475 326 SUPERFAMILY SSF51735 2 165 2.06E-34 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS12215 f1d05fe7a1be9cd2a17973de9e24f90b 535 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 133 152 1.8E-22 T 26-04-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4V04_RS12215 f1d05fe7a1be9cd2a17973de9e24f90b 535 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 432 446 1.8E-22 T 26-04-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4V04_RS12215 f1d05fe7a1be9cd2a17973de9e24f90b 535 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 359 381 1.8E-22 T 26-04-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4V04_RS12215 f1d05fe7a1be9cd2a17973de9e24f90b 535 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 491 504 1.8E-22 T 26-04-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4V04_RS12215 f1d05fe7a1be9cd2a17973de9e24f90b 535 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 417 431 1.8E-22 T 26-04-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4V04_RS12215 f1d05fe7a1be9cd2a17973de9e24f90b 535 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 128 514 1.8E-57 T 26-04-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4V04_RS12215 f1d05fe7a1be9cd2a17973de9e24f90b 535 Gene3D G3DSA:3.40.710.10 305 533 1.6E-64 T 26-04-2017 IPR012338 Beta-lactamase/transpeptidase-like A4V04_RS12215 f1d05fe7a1be9cd2a17973de9e24f90b 535 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 100 530 3.5E-74 T 26-04-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4V04_RS12215 f1d05fe7a1be9cd2a17973de9e24f90b 535 SUPERFAMILY SSF56601 91 533 5.17E-88 T 26-04-2017 IPR012338 Beta-lactamase/transpeptidase-like A4V04_RS11200 cb0c2b5bccc7cdfd1ccd64061a002fdd 307 SUPERFAMILY SSF103481 50 146 8.37E-6 T 26-04-2017 A4V04_RS11200 cb0c2b5bccc7cdfd1ccd64061a002fdd 307 SUPERFAMILY SSF103481 202 293 1.31E-10 T 26-04-2017 A4V04_RS11200 cb0c2b5bccc7cdfd1ccd64061a002fdd 307 Pfam PF00892 EamA-like transporter family 6 144 2.3E-12 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS11200 cb0c2b5bccc7cdfd1ccd64061a002fdd 307 Pfam PF00892 EamA-like transporter family 159 288 1.2E-17 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS07915 e73348c5fcda8001b0850b224c527148 252 Gene3D G3DSA:3.30.70.20 57 130 1.9E-12 T 26-04-2017 A4V04_RS07915 e73348c5fcda8001b0850b224c527148 252 Gene3D G3DSA:3.30.70.20 176 229 5.8E-18 T 26-04-2017 A4V04_RS07915 e73348c5fcda8001b0850b224c527148 252 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 156 167 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS07915 e73348c5fcda8001b0850b224c527148 252 SUPERFAMILY SSF54862 57 246 3.87E-57 T 26-04-2017 A4V04_RS07915 e73348c5fcda8001b0850b224c527148 252 Pfam PF00037 4Fe-4S binding domain 60 76 1.5E-4 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07915 e73348c5fcda8001b0850b224c527148 252 Pfam PF13247 4Fe-4S dicluster domain 117 212 4.4E-22 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07915 e73348c5fcda8001b0850b224c527148 252 Gene3D G3DSA:3.30.70.20 131 175 1.9E-21 T 26-04-2017 A4V04_RS10995 e429f739b3e00e83c2ee6dd9cdea3fcd 308 Gene3D G3DSA:3.40.50.720 1 146 8.5E-36 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS10995 e429f739b3e00e83c2ee6dd9cdea3fcd 308 PIRSF PIRSF000102 1 307 9.7E-83 T 26-04-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A4V04_RS10995 e429f739b3e00e83c2ee6dd9cdea3fcd 308 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 146 304 2.0E-13 T 26-04-2017 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 A4V04_RS10995 e429f739b3e00e83c2ee6dd9cdea3fcd 308 SUPERFAMILY SSF51735 1 145 4.24E-35 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS10995 e429f739b3e00e83c2ee6dd9cdea3fcd 308 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 3 143 2.3E-19 T 26-04-2017 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 A4V04_RS10995 e429f739b3e00e83c2ee6dd9cdea3fcd 308 PRINTS PR00086 L-lactate dehydrogenase signature 117 137 5.4E-26 T 26-04-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A4V04_RS10995 e429f739b3e00e83c2ee6dd9cdea3fcd 308 PRINTS PR00086 L-lactate dehydrogenase signature 141 159 5.4E-26 T 26-04-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A4V04_RS10995 e429f739b3e00e83c2ee6dd9cdea3fcd 308 PRINTS PR00086 L-lactate dehydrogenase signature 171 184 5.4E-26 T 26-04-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A4V04_RS10995 e429f739b3e00e83c2ee6dd9cdea3fcd 308 PRINTS PR00086 L-lactate dehydrogenase signature 3 27 5.4E-26 T 26-04-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A4V04_RS10995 e429f739b3e00e83c2ee6dd9cdea3fcd 308 PRINTS PR00086 L-lactate dehydrogenase signature 28 52 5.4E-26 T 26-04-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A4V04_RS10995 e429f739b3e00e83c2ee6dd9cdea3fcd 308 SUPERFAMILY SSF56327 144 302 8.36E-41 T 26-04-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4V04_RS10995 e429f739b3e00e83c2ee6dd9cdea3fcd 308 Gene3D G3DSA:3.90.110.10 147 301 1.5E-44 T 26-04-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4V04_RS05530 b19dc8054563f2350bba8ca59b8565ac 116 Gene3D G3DSA:2.40.160.50 23 95 2.0E-10 T 26-04-2017 A4V04_RS07695 ebc22fa321d9ecbc91e41ebbcdf7a2dd 273 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 7 270 3.4E-75 T 26-04-2017 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A4V04_RS07695 ebc22fa321d9ecbc91e41ebbcdf7a2dd 273 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 9 91 1.0E-22 T 26-04-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A4V04_RS07695 ebc22fa321d9ecbc91e41ebbcdf7a2dd 273 SUPERFAMILY SSF53223 5 103 2.71E-27 T 26-04-2017 A4V04_RS07695 ebc22fa321d9ecbc91e41ebbcdf7a2dd 273 Gene3D G3DSA:3.40.192.10 3 107 9.6E-35 T 26-04-2017 A4V04_RS07695 ebc22fa321d9ecbc91e41ebbcdf7a2dd 273 Gene3D G3DSA:3.40.50.720 108 269 1.7E-41 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS07695 ebc22fa321d9ecbc91e41ebbcdf7a2dd 273 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 119 191 8.1E-10 T 26-04-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A4V04_RS07695 ebc22fa321d9ecbc91e41ebbcdf7a2dd 273 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 4 272 30.724 T 26-04-2017 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A4V04_RS07695 ebc22fa321d9ecbc91e41ebbcdf7a2dd 273 SUPERFAMILY SSF51735 104 269 5.36E-37 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS02230 41eb6ce68e91d413211cfa28c73346e1 431 Gene3D G3DSA:3.50.50.60 1 221 1.0E-71 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02230 41eb6ce68e91d413211cfa28c73346e1 431 Gene3D G3DSA:3.50.50.60 368 429 1.0E-71 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02230 41eb6ce68e91d413211cfa28c73346e1 431 SUPERFAMILY SSF51905 371 428 7.79E-45 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02230 41eb6ce68e91d413211cfa28c73346e1 431 SUPERFAMILY SSF51905 2 229 7.79E-45 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02230 41eb6ce68e91d413211cfa28c73346e1 431 Gene3D G3DSA:3.90.700.10 227 363 6.0E-30 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02230 41eb6ce68e91d413211cfa28c73346e1 431 Pfam PF00890 FAD binding domain 1 412 1.9E-68 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02230 41eb6ce68e91d413211cfa28c73346e1 431 SUPERFAMILY SSF56425 227 372 3.89E-30 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02230 41eb6ce68e91d413211cfa28c73346e1 431 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 2 424 6.5E-113 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS07830 9401ca84b4412acb9419ee6117694099 301 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 264 275 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS07830 9401ca84b4412acb9419ee6117694099 301 Pfam PF13237 4Fe-4S dicluster domain 224 275 4.2E-11 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07830 9401ca84b4412acb9419ee6117694099 301 Gene3D G3DSA:3.30.70.20 110 115 2.4E-17 T 26-04-2017 A4V04_RS07830 9401ca84b4412acb9419ee6117694099 301 Gene3D G3DSA:3.30.70.20 198 292 2.4E-17 T 26-04-2017 A4V04_RS07830 9401ca84b4412acb9419ee6117694099 301 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 232 243 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS07830 9401ca84b4412acb9419ee6117694099 301 TIGRFAM TIGR02163 napH_: ferredoxin-type protein, NapH/MauN family 24 282 4.6E-85 T 26-04-2017 IPR011886 Ferredoxin-type protein, NapH/MauN family GO:0005506 A4V04_RS07830 9401ca84b4412acb9419ee6117694099 301 SUPERFAMILY SSF54862 198 283 2.55E-21 T 26-04-2017 A4V04_RS07830 9401ca84b4412acb9419ee6117694099 301 SUPERFAMILY SSF54862 99 148 2.55E-21 T 26-04-2017 A4V04_RS07830 9401ca84b4412acb9419ee6117694099 301 Pfam PF12801 4Fe-4S binding domain 88 133 1.7E-12 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS03520 afa4be1c10773532ebe0acfb2ecf3e5d 433 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 48 280 3.1E-16 T 26-04-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A4V04_RS03520 afa4be1c10773532ebe0acfb2ecf3e5d 433 SUPERFAMILY SSF111369 42 285 2.09E-58 T 26-04-2017 A4V04_RS03520 afa4be1c10773532ebe0acfb2ecf3e5d 433 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 27 361 1.0E-75 T 26-04-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 A4V04_RS03520 afa4be1c10773532ebe0acfb2ecf3e5d 433 Gene3D G3DSA:2.40.50.100 52 85 4.2E-17 T 26-04-2017 A4V04_RS03520 afa4be1c10773532ebe0acfb2ecf3e5d 433 Gene3D G3DSA:2.40.50.100 160 192 4.2E-17 T 26-04-2017 A4V04_RS02360 f524604e9bcb3d525c12c1c41b5be916 210 Pfam PF00072 Response regulator receiver domain 12 121 7.3E-24 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS02360 f524604e9bcb3d525c12c1c41b5be916 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 200 1.1E-15 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02360 f524604e9bcb3d525c12c1c41b5be916 210 SMART SM00421 144 201 3.0E-15 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02360 f524604e9bcb3d525c12c1c41b5be916 210 Gene3D G3DSA:3.40.50.2300 12 136 4.8E-30 T 26-04-2017 A4V04_RS02360 f524604e9bcb3d525c12c1c41b5be916 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 5.9E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02360 f524604e9bcb3d525c12c1c41b5be916 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 5.9E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02360 f524604e9bcb3d525c12c1c41b5be916 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 5.9E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02360 f524604e9bcb3d525c12c1c41b5be916 210 SUPERFAMILY SSF46894 138 205 7.82E-16 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS02360 f524604e9bcb3d525c12c1c41b5be916 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 161 188 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02360 f524604e9bcb3d525c12c1c41b5be916 210 Gene3D G3DSA:1.10.10.10 145 204 2.5E-18 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02360 f524604e9bcb3d525c12c1c41b5be916 210 SUPERFAMILY SSF52172 13 156 1.1E-32 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS02360 f524604e9bcb3d525c12c1c41b5be916 210 SMART SM00448 9 120 4.7E-25 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS05345 0d594e78b32e861011e7c5b07f9aa920 302 SUPERFAMILY SSF48576 9 276 3.29E-80 T 26-04-2017 IPR008949 Isoprenoid synthase domain A4V04_RS05345 0d594e78b32e861011e7c5b07f9aa920 302 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 216 228 - T 26-04-2017 IPR000092 Polyprenyl synthetase GO:0008299 A4V04_RS05345 0d594e78b32e861011e7c5b07f9aa920 302 Pfam PF00348 Polyprenyl synthetase 32 281 3.8E-53 T 26-04-2017 IPR000092 Polyprenyl synthetase GO:0008299 A4V04_RS05345 0d594e78b32e861011e7c5b07f9aa920 302 Gene3D G3DSA:1.10.600.10 4 276 5.6E-86 T 26-04-2017 IPR008949 Isoprenoid synthase domain A4V04_RS02250 3fa489d657a65c313225a53b1a734e0a 316 Gene3D G3DSA:1.10.10.10 10 86 4.8E-8 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02250 3fa489d657a65c313225a53b1a734e0a 316 Pfam PF03466 LysR substrate binding domain 97 305 2.0E-14 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS02250 3fa489d657a65c313225a53b1a734e0a 316 SUPERFAMILY SSF46785 7 116 1.63E-7 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02250 3fa489d657a65c313225a53b1a734e0a 316 Gene3D G3DSA:3.40.190.10 90 172 1.9E-16 T 26-04-2017 A4V04_RS02250 3fa489d657a65c313225a53b1a734e0a 316 Gene3D G3DSA:3.40.190.10 281 307 1.9E-16 T 26-04-2017 A4V04_RS02250 3fa489d657a65c313225a53b1a734e0a 316 SUPERFAMILY SSF53850 90 304 1.09E-21 T 26-04-2017 A4V04_RS02250 3fa489d657a65c313225a53b1a734e0a 316 Gene3D G3DSA:3.40.190.10 173 271 4.6E-4 T 26-04-2017 A4V04_RS09600 0d6d44c2217f819ad973b506f22d8750 1303 Pfam PF12447 Protein of unknown function (DUF3683) 13 131 1.1E-44 T 26-04-2017 IPR022153 Protein of unknown function DUF3683 A4V04_RS09600 0d6d44c2217f819ad973b506f22d8750 1303 SUPERFAMILY SSF56176 144 413 6.18E-56 T 26-04-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4V04_RS09600 0d6d44c2217f819ad973b506f22d8750 1303 Gene3D G3DSA:3.30.43.10 143 297 2.3E-34 T 26-04-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A4V04_RS09600 0d6d44c2217f819ad973b506f22d8750 1303 Pfam PF11880 Domain of unknown function (DUF3400) 1259 1303 6.1E-13 T 26-04-2017 IPR021817 Protein of unknown function DUF3400 A4V04_RS09600 0d6d44c2217f819ad973b506f22d8750 1303 Pfam PF02913 FAD linked oxidases, C-terminal domain 695 797 4.3E-13 T 26-04-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4V04_RS09600 0d6d44c2217f819ad973b506f22d8750 1303 Pfam PF02913 FAD linked oxidases, C-terminal domain 447 557 3.3E-6 T 26-04-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4V04_RS09600 0d6d44c2217f819ad973b506f22d8750 1303 SUPERFAMILY SSF46548 820 927 3.87E-13 T 26-04-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 A4V04_RS09600 0d6d44c2217f819ad973b506f22d8750 1303 SUPERFAMILY SSF55103 430 545 6.54E-33 T 26-04-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4V04_RS09600 0d6d44c2217f819ad973b506f22d8750 1303 SUPERFAMILY SSF55103 675 799 6.54E-33 T 26-04-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4V04_RS09600 0d6d44c2217f819ad973b506f22d8750 1303 Gene3D G3DSA:1.10.1060.10 821 927 6.0E-15 T 26-04-2017 A4V04_RS09600 0d6d44c2217f819ad973b506f22d8750 1303 Pfam PF13183 4Fe-4S dicluster domain 833 912 4.9E-8 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS09600 0d6d44c2217f819ad973b506f22d8750 1303 Pfam PF02754 Cysteine-rich domain 1167 1256 1.9E-4 T 26-04-2017 IPR004017 Cysteine-rich domain A4V04_RS09600 0d6d44c2217f819ad973b506f22d8750 1303 Pfam PF02754 Cysteine-rich domain 1041 1131 5.8E-7 T 26-04-2017 IPR004017 Cysteine-rich domain A4V04_RS09600 0d6d44c2217f819ad973b506f22d8750 1303 Pfam PF01565 FAD binding domain 181 326 3.7E-24 T 26-04-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4V04_RS08880 ffe8500463c864622b8b2f74404a2aef 112 SUPERFAMILY SSF48695 28 106 4.19E-14 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS08880 ffe8500463c864622b8b2f74404a2aef 112 Gene3D G3DSA:3.90.10.10 22 104 2.2E-13 T 26-04-2017 A4V04_RS08880 ffe8500463c864622b8b2f74404a2aef 112 Pfam PF14537 Cytochrome c3 27 104 8.4E-18 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 Gene3D G3DSA:3.30.70.100 2 71 1.2E-23 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 168 748 1.5E-184 T 26-04-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 SUPERFAMILY SSF56784 536 746 4.27E-58 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 SUPERFAMILY SSF56784 443 462 4.27E-58 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 SUPERFAMILY SSF55008 787 856 7.33E-18 T 26-04-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 795 855 2.9E-11 T 26-04-2017 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 2 66 2.4E-16 T 26-04-2017 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 890 951 1.9E-10 T 26-04-2017 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 Gene3D G3DSA:3.40.50.1000 567 707 2.2E-56 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 Gene3D G3DSA:3.40.50.1000 415 457 2.2E-56 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 216 719 3.3E-96 T 26-04-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 26-04-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 SUPERFAMILY SSF81653 247 344 1.19E-29 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 Gene3D G3DSA:3.40.1110.10 458 566 1.9E-19 T 26-04-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 SUPERFAMILY SSF55008 2 71 1.7E-19 T 26-04-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 ProSitePatterns PS01047 Heavy-metal-associated domain. 893 922 - T 26-04-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 SUPERFAMILY SSF81665 345 438 1.57E-13 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 SUPERFAMILY SSF81665 688 710 1.57E-13 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 SUPERFAMILY SSF81665 210 248 1.57E-13 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 152 749 2.8E-174 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 Gene3D G3DSA:2.70.150.10 184 345 1.0E-35 T 26-04-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 Pfam PF00403 Heavy-metal-associated domain 794 853 2.2E-16 T 26-04-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 Pfam PF00403 Heavy-metal-associated domain 5 64 4.5E-17 T 26-04-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 Pfam PF00403 Heavy-metal-associated domain 893 949 2.1E-14 T 26-04-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 ProSitePatterns PS01047 Heavy-metal-associated domain. 796 825 - T 26-04-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 446 452 - T 26-04-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 Gene3D G3DSA:3.30.70.100 889 951 5.9E-19 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 Gene3D G3DSA:3.30.70.100 792 854 9.9E-21 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 SUPERFAMILY SSF55008 888 953 4.58E-16 T 26-04-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 639 658 1.7E-31 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 662 674 1.7E-31 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 294 308 1.7E-31 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 586 596 1.7E-31 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 444 458 1.7E-31 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 564 575 1.7E-31 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 PRINTS PR00943 Copper-transporting ATPase signature 427 442 1.7E-8 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 PRINTS PR00943 Copper-transporting ATPase signature 367 381 1.7E-8 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 PRINTS PR00943 Copper-transporting ATPase signature 616 633 1.7E-8 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 PRINTS PR00943 Copper-transporting ATPase signature 46 66 1.7E-8 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 Pfam PF00702 haloacid dehalogenase-like hydrolase 440 653 4.2E-44 T 26-04-2017 A4V04_RS03680 ca18be610015bdcebdc47b56a5feae8c 956 Pfam PF00122 E1-E2 ATPase 215 435 1.8E-71 T 26-04-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4V04_RS02940 e0d988293140a73ae3919b903639dfd6 140 Pfam PF13470 PIN domain 3 110 1.3E-11 T 26-04-2017 IPR002716 PIN domain A4V04_RS02940 e0d988293140a73ae3919b903639dfd6 140 SMART SM00670 1 114 0.0036 T 26-04-2017 IPR002716 PIN domain A4V04_RS02940 e0d988293140a73ae3919b903639dfd6 140 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 3 115 8.8E-9 T 26-04-2017 IPR002850 PIN family, putative toxin-antitoxin system toxin component A4V04_RS02940 e0d988293140a73ae3919b903639dfd6 140 SUPERFAMILY SSF88723 1 118 1.28E-7 T 26-04-2017 IPR029060 PIN domain-like A4V04_RS07135 e6f29896b892ad72d834094dd6ee6fcc 427 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 73 86 3.1E-5 T 26-04-2017 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A4V04_RS07135 e6f29896b892ad72d834094dd6ee6fcc 427 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 141 159 3.1E-5 T 26-04-2017 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A4V04_RS07135 e6f29896b892ad72d834094dd6ee6fcc 427 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 199 212 3.1E-5 T 26-04-2017 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A4V04_RS07135 e6f29896b892ad72d834094dd6ee6fcc 427 Pfam PF08388 Group II intron, maturase-specific domain 300 373 4.1E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS07135 e6f29896b892ad72d834094dd6ee6fcc 427 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 78 285 1.0E-43 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS07135 e6f29896b892ad72d834094dd6ee6fcc 427 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 24 363 7.9E-113 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS07135 e6f29896b892ad72d834094dd6ee6fcc 427 SUPERFAMILY SSF56672 25 362 5.78E-59 T 26-04-2017 A4V04_RS06565 2d76ea5d3d55b8b70adf828ebbe1fd54 101 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 5 82 1.9E-22 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS06565 2d76ea5d3d55b8b70adf828ebbe1fd54 101 Pfam PF04221 RelB antitoxin 6 68 9.9E-19 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS06380 30e1b4a63534ff7148a35dd48524eec4 1128 Pfam PF03797 Autotransporter beta-domain 847 1110 5.4E-21 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS06380 30e1b4a63534ff7148a35dd48524eec4 1128 SMART SM00869 844 1117 1.3E-15 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS06380 30e1b4a63534ff7148a35dd48524eec4 1128 Gene3D G3DSA:2.40.128.130 843 1128 2.9E-24 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS06380 30e1b4a63534ff7148a35dd48524eec4 1128 SUPERFAMILY SSF103515 817 1128 2.75E-23 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS11560 92c9ee82e16c613219c6493799838b1c 151 SMART SM00900 33 106 5.2E-11 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS11560 92c9ee82e16c613219c6493799838b1c 151 Pfam PF04205 FMN-binding domain 33 104 2.9E-9 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS11560 92c9ee82e16c613219c6493799838b1c 151 Gene3D G3DSA:3.50.50.60 115 146 3.3E-5 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS00320 656a09fafa1d62594cc1215f6fd6fa98 431 Gene3D G3DSA:3.90.170.10 267 425 1.5E-64 T 26-04-2017 A4V04_RS00320 656a09fafa1d62594cc1215f6fd6fa98 431 Gene3D G3DSA:3.40.440.10 3 94 1.7E-67 T 26-04-2017 A4V04_RS00320 656a09fafa1d62594cc1215f6fd6fa98 431 Gene3D G3DSA:3.40.440.10 196 266 1.7E-67 T 26-04-2017 A4V04_RS00320 656a09fafa1d62594cc1215f6fd6fa98 431 SUPERFAMILY SSF52540 3 429 2.02E-171 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00320 656a09fafa1d62594cc1215f6fd6fa98 431 Gene3D G3DSA:1.10.300.10 103 195 5.8E-33 T 26-04-2017 A4V04_RS00320 656a09fafa1d62594cc1215f6fd6fa98 431 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 429 1.1E-176 T 26-04-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4V04_RS00320 656a09fafa1d62594cc1215f6fd6fa98 431 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 431 201.924 T 26-04-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4V04_RS00320 656a09fafa1d62594cc1215f6fd6fa98 431 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 26-04-2017 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4V04_RS00320 656a09fafa1d62594cc1215f6fd6fa98 431 SMART SM00788 4 424 3.2E-278 T 26-04-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4V04_RS00320 656a09fafa1d62594cc1215f6fd6fa98 431 Pfam PF00709 Adenylosuccinate synthetase 5 423 7.9E-170 T 26-04-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4V04_RS00320 656a09fafa1d62594cc1215f6fd6fa98 431 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 26-04-2017 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4V04_RS02980 db406a0c79c29d9fe86d9f9654e8dbd4 949 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 11 939 0.0 T 26-04-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4V04_RS02980 db406a0c79c29d9fe86d9f9654e8dbd4 949 Pfam PF00676 Dehydrogenase E1 component 216 519 5.0E-53 T 26-04-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 A4V04_RS02980 db406a0c79c29d9fe86d9f9654e8dbd4 949 SUPERFAMILY SSF52518 122 520 5.89E-84 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS02980 db406a0c79c29d9fe86d9f9654e8dbd4 949 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 798 939 1.9E-48 T 26-04-2017 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4V04_RS02980 db406a0c79c29d9fe86d9f9654e8dbd4 949 PIRSF PIRSF000157 2 941 0.0 T 26-04-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4V04_RS02980 db406a0c79c29d9fe86d9f9654e8dbd4 949 SUPERFAMILY SSF52518 579 799 5.4E-46 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS02980 db406a0c79c29d9fe86d9f9654e8dbd4 949 Gene3D G3DSA:3.40.50.970 598 802 8.6E-21 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS02980 db406a0c79c29d9fe86d9f9654e8dbd4 949 SMART SM00861 596 793 4.2E-54 T 26-04-2017 IPR005475 Transketolase-like, pyrimidine-binding domain A4V04_RS02980 db406a0c79c29d9fe86d9f9654e8dbd4 949 Gene3D G3DSA:3.40.50.970 163 520 1.4E-70 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS02980 db406a0c79c29d9fe86d9f9654e8dbd4 949 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 8 47 9.2E-19 T 26-04-2017 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4V04_RS02980 db406a0c79c29d9fe86d9f9654e8dbd4 949 Pfam PF02779 Transketolase, pyrimidine binding domain 596 793 2.3E-61 T 26-04-2017 IPR005475 Transketolase-like, pyrimidine-binding domain A4V04_RS08190 48f8c1531807c874840faab9d49be424 130 PRINTS PR00502 NUDIX hydrolase family signature 31 45 3.1E-7 T 26-04-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4V04_RS08190 48f8c1531807c874840faab9d49be424 130 PRINTS PR00502 NUDIX hydrolase family signature 45 60 3.1E-7 T 26-04-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4V04_RS08190 48f8c1531807c874840faab9d49be424 130 Gene3D G3DSA:3.90.79.10 3 123 8.6E-34 T 26-04-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4V04_RS08190 48f8c1531807c874840faab9d49be424 130 SUPERFAMILY SSF55811 2 124 2.57E-32 T 26-04-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4V04_RS08190 48f8c1531807c874840faab9d49be424 130 Pfam PF00293 NUDIX domain 6 108 1.7E-18 T 26-04-2017 IPR000086 NUDIX hydrolase domain GO:0016787 A4V04_RS10735 f6eb6c3fb6251deefae2c37ca2c9d2cc 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 65 1.3E-13 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10735 f6eb6c3fb6251deefae2c37ca2c9d2cc 305 SUPERFAMILY SSF53850 93 300 1.59E-26 T 26-04-2017 A4V04_RS10735 f6eb6c3fb6251deefae2c37ca2c9d2cc 305 Gene3D G3DSA:3.40.190.10 95 178 5.1E-13 T 26-04-2017 A4V04_RS10735 f6eb6c3fb6251deefae2c37ca2c9d2cc 305 SUPERFAMILY SSF46785 8 85 2.45E-14 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10735 f6eb6c3fb6251deefae2c37ca2c9d2cc 305 Gene3D G3DSA:1.10.10.10 10 88 1.3E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10735 f6eb6c3fb6251deefae2c37ca2c9d2cc 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 3.6E-5 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10735 f6eb6c3fb6251deefae2c37ca2c9d2cc 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 3.6E-5 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10735 f6eb6c3fb6251deefae2c37ca2c9d2cc 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 3.6E-5 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10735 f6eb6c3fb6251deefae2c37ca2c9d2cc 305 Pfam PF03466 LysR substrate binding domain 91 296 5.1E-20 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS10735 f6eb6c3fb6251deefae2c37ca2c9d2cc 305 Gene3D G3DSA:3.40.190.10 179 264 3.7E-10 T 26-04-2017 A4V04_RS04155 6dd34783abe66f8c4050682fd79f35e1 128 SMART SM00671 84 119 2.4E-5 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04155 6dd34783abe66f8c4050682fd79f35e1 128 SMART SM00671 52 83 5.5 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04155 6dd34783abe66f8c4050682fd79f35e1 128 SUPERFAMILY SSF81901 33 125 1.83E-20 T 26-04-2017 A4V04_RS04155 6dd34783abe66f8c4050682fd79f35e1 128 Gene3D G3DSA:1.25.40.10 33 126 1.1E-19 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS11500 c7f6e7fd3d6ccb3fe6b8197332cf644d 346 SUPERFAMILY SSF51412 6 337 7.85E-95 T 26-04-2017 A4V04_RS11500 c7f6e7fd3d6ccb3fe6b8197332cf644d 346 Hamap MF_00596 GMP reductase [guaC]. 1 344 52.087 T 26-04-2017 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 A4V04_RS11500 c7f6e7fd3d6ccb3fe6b8197332cf644d 346 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 9 338 3.2E-77 T 26-04-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A4V04_RS11500 c7f6e7fd3d6ccb3fe6b8197332cf644d 346 SMART SM01240 7 346 1.4E-122 T 26-04-2017 A4V04_RS11500 c7f6e7fd3d6ccb3fe6b8197332cf644d 346 PIRSF PIRSF000235 1 346 7.3E-175 T 26-04-2017 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 A4V04_RS11500 c7f6e7fd3d6ccb3fe6b8197332cf644d 346 Gene3D G3DSA:3.20.20.70 3 342 4.0E-107 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS11500 c7f6e7fd3d6ccb3fe6b8197332cf644d 346 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 175 187 - T 26-04-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A4V04_RS11500 c7f6e7fd3d6ccb3fe6b8197332cf644d 346 TIGRFAM TIGR01305 GMP_reduct_1: guanosine monophosphate reductase 3 343 5.5E-165 T 26-04-2017 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 A4V04_RS04875 a6e8f659d4e13c0d1811807dc23bebeb 308 Gene3D G3DSA:3.40.1090.10 7 170 1.7E-9 T 26-04-2017 A4V04_RS04875 a6e8f659d4e13c0d1811807dc23bebeb 308 Pfam PF01734 Patatin-like phospholipase 110 165 4.7E-6 T 26-04-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 A4V04_RS04875 a6e8f659d4e13c0d1811807dc23bebeb 308 Pfam PF01734 Patatin-like phospholipase 6 68 8.8E-12 T 26-04-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 A4V04_RS04875 a6e8f659d4e13c0d1811807dc23bebeb 308 SUPERFAMILY SSF52151 1 283 2.12E-45 T 26-04-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A4V04_RS12530 523d13667e2a57e2d60fddeffd2231a5 239 SUPERFAMILY SSF53335 13 238 2.69E-34 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS12530 523d13667e2a57e2d60fddeffd2231a5 239 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 22 239 28.445 T 26-04-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A4V04_RS12530 523d13667e2a57e2d60fddeffd2231a5 239 Gene3D G3DSA:3.40.50.150 59 217 2.2E-16 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS12530 523d13667e2a57e2d60fddeffd2231a5 239 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 54 238 1.7E-51 T 26-04-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A4V04_RS12530 523d13667e2a57e2d60fddeffd2231a5 239 Pfam PF02390 Putative methyltransferase 62 234 3.8E-51 T 26-04-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A4V04_RS06915 624327e673a8dd98e48e16a2acca5ea0 679 SMART SM00382 191 330 5.4E-26 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS06915 624327e673a8dd98e48e16a2acca5ea0 679 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 195 327 3.5E-45 T 26-04-2017 IPR003959 ATPase, AAA-type, core GO:0005524 A4V04_RS06915 624327e673a8dd98e48e16a2acca5ea0 679 SUPERFAMILY SSF52540 153 398 1.52E-72 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06915 624327e673a8dd98e48e16a2acca5ea0 679 Gene3D G3DSA:3.40.50.300 155 338 5.8E-64 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06915 624327e673a8dd98e48e16a2acca5ea0 679 Pfam PF06480 FtsH Extracellular 12 83 2.4E-7 T 26-04-2017 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 A4V04_RS06915 624327e673a8dd98e48e16a2acca5ea0 679 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 619 37.411 T 26-04-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 A4V04_RS06915 624327e673a8dd98e48e16a2acca5ea0 679 SUPERFAMILY SSF140990 410 607 6.67E-76 T 26-04-2017 A4V04_RS06915 624327e673a8dd98e48e16a2acca5ea0 679 Pfam PF01434 Peptidase family M41 389 597 2.2E-81 T 26-04-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 A4V04_RS06915 624327e673a8dd98e48e16a2acca5ea0 679 ProSitePatterns PS00674 AAA-protein family signature. 298 316 - T 26-04-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A4V04_RS06915 624327e673a8dd98e48e16a2acca5ea0 679 Gene3D G3DSA:1.10.8.60 339 412 4.7E-29 T 26-04-2017 A4V04_RS06915 624327e673a8dd98e48e16a2acca5ea0 679 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 107 598 1.1E-239 T 26-04-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 A4V04_RS10275 77cc04e8b4875a142ed46ca8d09b90ce 157 PIRSF PIRSF016487 1 157 9.7E-55 T 26-04-2017 IPR012042 Inorganic triphosphatase NeuTTM/CthTTM-like A4V04_RS10275 77cc04e8b4875a142ed46ca8d09b90ce 157 SMART SM01118 2 152 2.4E-21 T 26-04-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 A4V04_RS10275 77cc04e8b4875a142ed46ca8d09b90ce 157 SUPERFAMILY SSF55154 4 148 1.8E-42 T 26-04-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 A4V04_RS10275 77cc04e8b4875a142ed46ca8d09b90ce 157 Gene3D G3DSA:2.40.320.10 3 152 5.1E-52 T 26-04-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 A4V04_RS10275 77cc04e8b4875a142ed46ca8d09b90ce 157 Pfam PF01928 CYTH domain 3 142 7.0E-13 T 26-04-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 Gene3D G3DSA:3.40.50.1370 4 144 4.9E-54 T 26-04-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 SUPERFAMILY SSF53671 5 332 2.36E-94 T 26-04-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 331 3.4E-48 T 26-04-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 4.8E-44 T 26-04-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 9.4E-25 T 26-04-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 9.4E-25 T 26-04-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 9.4E-25 T 26-04-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 298 321 9.4E-25 T 26-04-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 1.6E-27 T 26-04-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 1.6E-27 T 26-04-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 312 323 1.6E-27 T 26-04-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 1.6E-27 T 26-04-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 1.6E-27 T 26-04-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 333 5.2E-124 T 26-04-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 334 77.573 T 26-04-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 Gene3D G3DSA:3.40.50.1370 145 320 6.6E-67 T 26-04-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4V04_RS06940 76e753f79b34ebfb9d11985925968e02 334 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 26-04-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 PRINTS PR00987 Glutamyl-tRNA synthetase signature 186 196 1.2E-22 T 26-04-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 1.2E-22 T 26-04-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 1.2E-22 T 26-04-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 PRINTS PR00987 Glutamyl-tRNA synthetase signature 202 210 1.2E-22 T 26-04-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 1.2E-22 T 26-04-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 SUPERFAMILY SSF48163 306 466 4.32E-33 T 26-04-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 Gene3D G3DSA:1.10.10.350 384 466 2.3E-17 T 26-04-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 Gene3D G3DSA:1.10.1160.10 240 321 1.5E-32 T 26-04-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 Gene3D G3DSA:3.90.800.10 70 187 5.2E-33 T 26-04-2017 A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 SUPERFAMILY SSF52374 4 304 3.58E-104 T 26-04-2017 A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 312 2.2E-99 T 26-04-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 26-04-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 Gene3D G3DSA:3.40.50.620 4 69 6.0E-47 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 Gene3D G3DSA:3.40.50.620 188 237 6.0E-47 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 466 3.2E-169 T 26-04-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4V04_RS01240 19d81e74a7ee6886c3b39195212dc236 476 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 5 468 32.17 T 26-04-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4V04_RS09480 eaf2dc4aad5f9163de97f1071438dd05 379 Pfam PF13635 Domain of unknown function (DUF4143) 186 344 1.7E-21 T 26-04-2017 IPR025420 Domain of unknown function DUF4143 A4V04_RS09480 eaf2dc4aad5f9163de97f1071438dd05 379 Gene3D G3DSA:3.40.50.300 7 111 5.4E-8 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09480 eaf2dc4aad5f9163de97f1071438dd05 379 Gene3D G3DSA:1.10.10.10 205 246 9.1E-4 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09480 eaf2dc4aad5f9163de97f1071438dd05 379 Pfam PF13173 AAA domain 18 139 1.3E-20 T 26-04-2017 A4V04_RS09480 eaf2dc4aad5f9163de97f1071438dd05 379 SUPERFAMILY SSF52540 8 146 2.0E-16 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08135 99335764c638f99f27ba17408524ff9e 558 SUPERFAMILY SSF53649 251 542 4.14E-14 T 26-04-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A4V04_RS08135 99335764c638f99f27ba17408524ff9e 558 Pfam PF00884 Sulfatase 251 539 8.4E-43 T 26-04-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 A4V04_RS08135 99335764c638f99f27ba17408524ff9e 558 Gene3D G3DSA:3.40.720.10 397 544 9.5E-8 T 26-04-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A4V04_RS08135 99335764c638f99f27ba17408524ff9e 558 Pfam PF08019 Domain of unknown function (DUF1705) 75 220 1.2E-28 T 26-04-2017 IPR012549 Domain of unknown function DUF1705 GO:0016021 A4V04_RS04370 25294f6b87ece1b166ea2f77c7a016b6 552 SUPERFAMILY SSF143975 1 371 3.27E-141 T 26-04-2017 A4V04_RS04370 25294f6b87ece1b166ea2f77c7a016b6 552 Pfam PF00920 Dehydratase family 31 549 3.4E-226 T 26-04-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4V04_RS04370 25294f6b87ece1b166ea2f77c7a016b6 552 SUPERFAMILY SSF52016 372 551 1.33E-63 T 26-04-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A4V04_RS04370 25294f6b87ece1b166ea2f77c7a016b6 552 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 552 47.15 T 26-04-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4V04_RS04370 25294f6b87ece1b166ea2f77c7a016b6 552 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 26-04-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4V04_RS04370 25294f6b87ece1b166ea2f77c7a016b6 552 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 460 471 - T 26-04-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4V04_RS04370 25294f6b87ece1b166ea2f77c7a016b6 552 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 551 4.5E-239 T 26-04-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 Gene3D G3DSA:2.30.42.10 396 484 1.2E-21 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 Gene3D G3DSA:2.30.42.10 289 383 6.2E-28 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 Gene3D G3DSA:2.40.10.10 39 67 4.6E-36 T 26-04-2017 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 Gene3D G3DSA:2.40.10.10 102 178 4.6E-36 T 26-04-2017 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 SUPERFAMILY SSF50156 396 481 4.47E-18 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 Pfam PF13180 PDZ domain 396 480 3.2E-14 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 Pfam PF13180 PDZ domain 295 378 1.3E-14 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 47 476 1.6E-148 T 26-04-2017 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 Gene3D G3DSA:2.40.10.10 179 288 5.3E-45 T 26-04-2017 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 PRINTS PR00834 HtrA/DegQ protease family signature 219 236 6.5E-50 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 PRINTS PR00834 HtrA/DegQ protease family signature 145 165 6.5E-50 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 PRINTS PR00834 HtrA/DegQ protease family signature 327 339 6.5E-50 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 PRINTS PR00834 HtrA/DegQ protease family signature 241 258 6.5E-50 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 PRINTS PR00834 HtrA/DegQ protease family signature 185 209 6.5E-50 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 PRINTS PR00834 HtrA/DegQ protease family signature 124 136 6.5E-50 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 SMART SM00228 395 471 1.7E-12 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 SMART SM00228 287 369 2.4E-10 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 SUPERFAMILY SSF50156 245 370 3.02E-23 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 SUPERFAMILY SSF50494 45 278 8.66E-66 T 26-04-2017 IPR009003 Peptidase S1, PA clan A4V04_RS06165 d46acae0dc8e46dffc6b5d066b84e46e 489 Pfam PF13365 Trypsin-like peptidase domain 115 248 1.8E-37 T 26-04-2017 A4V04_RS03485 1eea8d79274dfebf832087c5d016ea2e 376 SUPERFAMILY SSF51735 2 146 2.31E-47 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03485 1eea8d79274dfebf832087c5d016ea2e 376 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 265 279 - T 26-04-2017 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4V04_RS03485 1eea8d79274dfebf832087c5d016ea2e 376 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 143 357 3.4E-53 T 26-04-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4V04_RS03485 1eea8d79274dfebf832087c5d016ea2e 376 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 120 3.3E-22 T 26-04-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4V04_RS03485 1eea8d79274dfebf832087c5d016ea2e 376 SMART SM00859 2 121 3.4E-20 T 26-04-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4V04_RS03485 1eea8d79274dfebf832087c5d016ea2e 376 Gene3D G3DSA:3.30.360.10 142 354 1.1E-70 T 26-04-2017 A4V04_RS03485 1eea8d79274dfebf832087c5d016ea2e 376 Gene3D G3DSA:3.40.50.720 2 141 2.6E-56 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03485 1eea8d79274dfebf832087c5d016ea2e 376 PIRSF PIRSF000148 1 374 2.6E-60 T 26-04-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4V04_RS03485 1eea8d79274dfebf832087c5d016ea2e 376 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 2 371 1.0E-182 T 26-04-2017 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4V04_RS03485 1eea8d79274dfebf832087c5d016ea2e 376 SUPERFAMILY SSF55347 133 358 2.07E-73 T 26-04-2017 A4V04_RS06015 8275d02ee168c42e0ace8a34c19b4fab 496 SUPERFAMILY SSF51905 20 286 1.71E-57 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS06015 8275d02ee168c42e0ace8a34c19b4fab 496 SUPERFAMILY SSF51905 434 492 1.71E-57 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS06015 8275d02ee168c42e0ace8a34c19b4fab 496 Gene3D G3DSA:3.50.50.60 431 495 1.4E-86 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS06015 8275d02ee168c42e0ace8a34c19b4fab 496 Gene3D G3DSA:3.50.50.60 23 269 1.4E-86 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS06015 8275d02ee168c42e0ace8a34c19b4fab 496 SUPERFAMILY SSF56425 299 435 4.81E-25 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS06015 8275d02ee168c42e0ace8a34c19b4fab 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 440 462 1.3E-5 T 26-04-2017 A4V04_RS06015 8275d02ee168c42e0ace8a34c19b4fab 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 31 50 1.3E-5 T 26-04-2017 A4V04_RS06015 8275d02ee168c42e0ace8a34c19b4fab 496 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 30 488 3.5E-122 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS06015 8275d02ee168c42e0ace8a34c19b4fab 496 Pfam PF00890 FAD binding domain 30 476 3.3E-77 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS06015 8275d02ee168c42e0ace8a34c19b4fab 496 Gene3D G3DSA:3.90.700.10 300 426 8.1E-22 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS09665 c4a381323e306b0d00dc3b9cd80927a2 388 Gene3D G3DSA:1.20.1090.10 188 387 8.1E-44 T 26-04-2017 A4V04_RS09665 c4a381323e306b0d00dc3b9cd80927a2 388 SUPERFAMILY SSF56796 2 387 2.09E-97 T 26-04-2017 A4V04_RS09665 c4a381323e306b0d00dc3b9cd80927a2 388 Gene3D G3DSA:3.40.50.1970 1 187 1.2E-58 T 26-04-2017 A4V04_RS09665 c4a381323e306b0d00dc3b9cd80927a2 388 Pfam PF00465 Iron-containing alcohol dehydrogenase 7 378 1.5E-99 T 26-04-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A4V04_RS06935 cdf058bd2d1129fc2f7dbfb2c2163691 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 156 3.7E-27 T 26-04-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A4V04_RS06935 cdf058bd2d1129fc2f7dbfb2c2163691 157 Hamap MF_00105 Transcription elongation factor GreA [greA]. 1 155 31.075 T 26-04-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 A4V04_RS06935 cdf058bd2d1129fc2f7dbfb2c2163691 157 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 120 136 - T 26-04-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A4V04_RS06935 cdf058bd2d1129fc2f7dbfb2c2163691 157 Pfam PF03449 Transcription elongation factor, N-terminal 3 73 5.8E-29 T 26-04-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A4V04_RS06935 cdf058bd2d1129fc2f7dbfb2c2163691 157 Gene3D G3DSA:3.10.50.30 81 156 8.6E-30 T 26-04-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A4V04_RS06935 cdf058bd2d1129fc2f7dbfb2c2163691 157 PIRSF PIRSF006092 1 157 1.1E-48 T 26-04-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 A4V04_RS06935 cdf058bd2d1129fc2f7dbfb2c2163691 157 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 16 47 - T 26-04-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A4V04_RS06935 cdf058bd2d1129fc2f7dbfb2c2163691 157 SUPERFAMILY SSF46557 3 76 1.96E-25 T 26-04-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A4V04_RS06935 cdf058bd2d1129fc2f7dbfb2c2163691 157 SUPERFAMILY SSF54534 82 156 7.98E-22 T 26-04-2017 A4V04_RS06935 cdf058bd2d1129fc2f7dbfb2c2163691 157 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 4 155 3.6E-53 T 26-04-2017 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 A4V04_RS06935 cdf058bd2d1129fc2f7dbfb2c2163691 157 Gene3D G3DSA:1.10.287.180 3 74 2.5E-31 T 26-04-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A4V04_RS10855 f39364668a1f6fee8dd723216f272fbf 456 Gene3D G3DSA:3.30.565.10 270 441 4.9E-41 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10855 f39364668a1f6fee8dd723216f272fbf 456 SUPERFAMILY SSF47384 201 283 1.79E-16 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10855 f39364668a1f6fee8dd723216f272fbf 456 Pfam PF08521 Two-component sensor kinase N-terminal 20 138 1.6E-4 T 26-04-2017 IPR013727 Two-component sensor kinase, N-terminal A4V04_RS10855 f39364668a1f6fee8dd723216f272fbf 456 SMART SM00388 218 283 4.8E-15 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10855 f39364668a1f6fee8dd723216f272fbf 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 219 281 8.3E-13 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10855 f39364668a1f6fee8dd723216f272fbf 456 Gene3D G3DSA:1.10.287.130 210 269 7.7E-14 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10855 f39364668a1f6fee8dd723216f272fbf 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 329 438 2.8E-22 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10855 f39364668a1f6fee8dd723216f272fbf 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 393 1.1E-16 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS10855 f39364668a1f6fee8dd723216f272fbf 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 416 1.1E-16 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS10855 f39364668a1f6fee8dd723216f272fbf 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 379 1.1E-16 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS10855 f39364668a1f6fee8dd723216f272fbf 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 436 1.1E-16 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS10855 f39364668a1f6fee8dd723216f272fbf 456 SMART SM00387 328 439 9.5E-37 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10855 f39364668a1f6fee8dd723216f272fbf 456 SUPERFAMILY SSF55874 273 439 3.27E-40 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS09660 f25aba13da52e963ae29cbf86ad10922 296 SUPERFAMILY SSF55116 3 179 1.24E-62 T 26-04-2017 IPR022384 Formiminotransferase subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 A4V04_RS09660 f25aba13da52e963ae29cbf86ad10922 296 SUPERFAMILY SSF55116 181 288 4.97E-32 T 26-04-2017 IPR022384 Formiminotransferase subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 A4V04_RS09660 f25aba13da52e963ae29cbf86ad10922 296 TIGRFAM TIGR02024 FtcD: glutamate formiminotransferase 1 295 1.8E-109 T 26-04-2017 IPR004227 Formiminotransferase catalytic domain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4V04_RS09660 f25aba13da52e963ae29cbf86ad10922 296 Gene3D G3DSA:3.30.70.670 182 292 1.9E-36 T 26-04-2017 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4V04_RS09660 f25aba13da52e963ae29cbf86ad10922 296 Pfam PF07837 Formiminotransferase domain, N-terminal subdomain 4 179 2.2E-65 T 26-04-2017 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 A4V04_RS09660 f25aba13da52e963ae29cbf86ad10922 296 Gene3D G3DSA:3.30.990.10 3 179 6.3E-68 T 26-04-2017 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 A4V04_RS09660 f25aba13da52e963ae29cbf86ad10922 296 SMART SM01222 3 180 3.4E-86 T 26-04-2017 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 A4V04_RS09660 f25aba13da52e963ae29cbf86ad10922 296 Pfam PF02971 Formiminotransferase domain 182 283 1.1E-19 T 26-04-2017 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4V04_RS09660 f25aba13da52e963ae29cbf86ad10922 296 SMART SM01221 181 295 2.9E-46 T 26-04-2017 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4V04_RS02820 98e5ad4d4079f1f7933d7d8230785fb9 198 PIRSF PIRSF006305 1 194 1.3E-43 T 26-04-2017 IPR003697 Maf-like protein GO:0005737 A4V04_RS02820 98e5ad4d4079f1f7933d7d8230785fb9 198 TIGRFAM TIGR00172 maf: septum formation protein Maf 4 186 2.3E-43 T 26-04-2017 IPR003697 Maf-like protein GO:0005737 A4V04_RS02820 98e5ad4d4079f1f7933d7d8230785fb9 198 Gene3D G3DSA:3.90.950.10 5 192 3.7E-52 T 26-04-2017 IPR029001 Inosine triphosphate pyrophosphatase-like A4V04_RS02820 98e5ad4d4079f1f7933d7d8230785fb9 198 Pfam PF02545 Maf-like protein 7 188 1.1E-39 T 26-04-2017 IPR003697 Maf-like protein GO:0005737 A4V04_RS02820 98e5ad4d4079f1f7933d7d8230785fb9 198 Hamap MF_00528 Septum formation protein Maf [maf]. 6 193 26.036 T 26-04-2017 IPR003697 Maf-like protein GO:0005737 A4V04_RS02820 98e5ad4d4079f1f7933d7d8230785fb9 198 SUPERFAMILY SSF52972 5 188 2.03E-49 T 26-04-2017 IPR029001 Inosine triphosphate pyrophosphatase-like A4V04_RS11345 82cfecf44f638c72a6e10ba5471f450f 207 SMART SM00363 97 161 3.5E-17 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS11345 82cfecf44f638c72a6e10ba5471f450f 207 Gene3D G3DSA:3.10.290.10 103 191 1.3E-32 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS11345 82cfecf44f638c72a6e10ba5471f450f 207 Gene3D G3DSA:1.10.1050.10 1 102 2.8E-38 T 26-04-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A4V04_RS11345 82cfecf44f638c72a6e10ba5471f450f 207 ProSitePatterns PS00632 Ribosomal protein S4 signature. 95 119 - T 26-04-2017 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11345 82cfecf44f638c72a6e10ba5471f450f 207 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 207 34.863 T 26-04-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4V04_RS11345 82cfecf44f638c72a6e10ba5471f450f 207 SMART SM01390 3 96 1.6E-40 T 26-04-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A4V04_RS11345 82cfecf44f638c72a6e10ba5471f450f 207 Pfam PF01479 S4 domain 98 144 6.3E-20 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS11345 82cfecf44f638c72a6e10ba5471f450f 207 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 207 1.7E-78 T 26-04-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4V04_RS11345 82cfecf44f638c72a6e10ba5471f450f 207 SUPERFAMILY SSF55174 3 207 6.93E-66 T 26-04-2017 A4V04_RS11345 82cfecf44f638c72a6e10ba5471f450f 207 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 96 2.8E-28 T 26-04-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A4V04_RS09930 a92be4765df8c80a36ed54c69130590f 89 Gene3D G3DSA:3.30.1340.10 1 87 7.6E-30 T 26-04-2017 IPR000032 Phosphocarrier protein HPr-like A4V04_RS09930 a92be4765df8c80a36ed54c69130590f 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 8.8E-26 T 26-04-2017 IPR000032 Phosphocarrier protein HPr-like A4V04_RS09930 a92be4765df8c80a36ed54c69130590f 89 SUPERFAMILY SSF55594 4 87 1.96E-25 T 26-04-2017 IPR000032 Phosphocarrier protein HPr-like A4V04_RS09930 a92be4765df8c80a36ed54c69130590f 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 26-04-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site A4V04_RS09930 a92be4765df8c80a36ed54c69130590f 89 Pfam PF00381 PTS HPr component phosphorylation site 3 82 2.5E-25 T 26-04-2017 IPR000032 Phosphocarrier protein HPr-like A4V04_RS09930 a92be4765df8c80a36ed54c69130590f 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.2E-16 T 26-04-2017 IPR000032 Phosphocarrier protein HPr-like A4V04_RS09930 a92be4765df8c80a36ed54c69130590f 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.2E-16 T 26-04-2017 IPR000032 Phosphocarrier protein HPr-like A4V04_RS09930 a92be4765df8c80a36ed54c69130590f 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.2E-16 T 26-04-2017 IPR000032 Phosphocarrier protein HPr-like A4V04_RS08910 15b2436de778264e2980a2151ea4962c 469 Pfam PF02321 Outer membrane efflux protein 64 243 2.8E-29 T 26-04-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A4V04_RS08910 15b2436de778264e2980a2151ea4962c 469 Pfam PF02321 Outer membrane efflux protein 274 452 9.3E-24 T 26-04-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A4V04_RS08910 15b2436de778264e2980a2151ea4962c 469 Gene3D G3DSA:1.20.1600.10 54 457 2.9E-100 T 26-04-2017 A4V04_RS08910 15b2436de778264e2980a2151ea4962c 469 SUPERFAMILY SSF56954 2 455 5.36E-100 T 26-04-2017 A4V04_RS08910 15b2436de778264e2980a2151ea4962c 469 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 454 2.8E-89 T 26-04-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 Hamap MF_02004 Valine--tRNA ligase [valS]. 9 948 15.51 T 26-04-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 624 4.3E-192 T 26-04-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 SUPERFAMILY SSF46589 883 947 3.5E-17 T 26-04-2017 IPR010978 tRNA-binding arm GO:0000166 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 Gene3D G3DSA:3.40.50.620 348 564 2.3E-129 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 Gene3D G3DSA:3.40.50.620 11 200 2.3E-129 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 Gene3D G3DSA:3.40.50.620 602 623 2.3E-129 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 50 61 - T 26-04-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 TIGRFAM TIGR00422 valS: valine--tRNA ligase 10 929 0.0 T 26-04-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 Pfam PF08264 Anticodon-binding domain of tRNA 667 822 4.7E-44 T 26-04-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 883 947 1.4E-21 T 26-04-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 Gene3D G3DSA:1.10.287.380 880 947 2.9E-9 T 26-04-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 PRINTS PR00986 Valyl-tRNA synthetase signature 499 517 9.2E-33 T 26-04-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 PRINTS PR00986 Valyl-tRNA synthetase signature 237 254 9.2E-33 T 26-04-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 PRINTS PR00986 Valyl-tRNA synthetase signature 43 54 9.2E-33 T 26-04-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 PRINTS PR00986 Valyl-tRNA synthetase signature 463 484 9.2E-33 T 26-04-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 PRINTS PR00986 Valyl-tRNA synthetase signature 353 366 9.2E-33 T 26-04-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 SUPERFAMILY SSF52374 602 634 2.07E-125 T 26-04-2017 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 SUPERFAMILY SSF52374 9 199 2.07E-125 T 26-04-2017 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 SUPERFAMILY SSF52374 348 564 2.07E-125 T 26-04-2017 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 SUPERFAMILY SSF50677 198 349 2.49E-62 T 26-04-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 Gene3D G3DSA:3.90.740.10 201 344 2.2E-50 T 26-04-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 Gene3D G3DSA:1.10.730.10 624 813 3.9E-61 T 26-04-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS04740 2d594089506e4be16f3e146a7951fe07 948 SUPERFAMILY SSF47323 635 898 5.23E-66 T 26-04-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 159 316 5.4E-67 T 26-04-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 152 159 - T 26-04-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 Gene3D G3DSA:3.40.50.720 1 162 6.0E-67 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 231 248 4.8E-37 T 26-04-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 4.8E-37 T 26-04-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 4.8E-37 T 26-04-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 148 166 4.8E-37 T 26-04-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 175 191 4.8E-37 T 26-04-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 PIRSF PIRSF000149 1 337 3.0E-135 T 26-04-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 SUPERFAMILY SSF51735 1 176 1.96E-58 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 SUPERFAMILY SSF55347 154 317 1.46E-69 T 26-04-2017 A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 Gene3D G3DSA:3.30.360.10 163 318 5.1E-75 T 26-04-2017 A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 328 1.0E-129 T 26-04-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 154 3.3E-54 T 26-04-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07615 c4c121ac6e5cb4eb243e0a04e839365b 337 SMART SM00846 3 154 2.2E-83 T 26-04-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS13075 afc1d33e3536066e74312501d5626d67 299 Gene3D G3DSA:3.90.1150.10 155 293 1.3E-35 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS13075 afc1d33e3536066e74312501d5626d67 299 Pfam PF00155 Aminotransferase class I and II 3 288 3.8E-33 T 26-04-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4V04_RS13075 afc1d33e3536066e74312501d5626d67 299 Gene3D G3DSA:3.40.640.10 2 154 1.1E-40 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS13075 afc1d33e3536066e74312501d5626d67 299 SUPERFAMILY SSF53383 2 293 2.1E-74 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 Gene3D G3DSA:3.40.1160.10 9 268 1.5E-56 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 Hamap MF_00456 Glutamate 5-kinase [proB]. 12 265 34.64 T 26-04-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 ProSitePatterns PS00902 Glutamate 5-kinase signature. 214 231 - T 26-04-2017 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 SUPERFAMILY SSF53633 12 263 2.09E-67 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 PIRSF PIRSF000729 7 375 2.0E-127 T 26-04-2017 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 SUPERFAMILY SSF88697 284 373 2.93E-22 T 26-04-2017 IPR015947 PUA-like domain A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 Pfam PF00696 Amino acid kinase family 12 241 3.0E-42 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 PRINTS PR00474 Glutamate 5-kinase family signature 155 182 2.5E-48 T 26-04-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 PRINTS PR00474 Glutamate 5-kinase family signature 123 144 2.5E-48 T 26-04-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 PRINTS PR00474 Glutamate 5-kinase family signature 49 63 2.5E-48 T 26-04-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 PRINTS PR00474 Glutamate 5-kinase family signature 83 111 2.5E-48 T 26-04-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 PRINTS PR00474 Glutamate 5-kinase family signature 216 236 2.5E-48 T 26-04-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 Pfam PF01472 PUA domain 284 355 1.1E-21 T 26-04-2017 IPR002478 PUA domain GO:0003723 A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 Gene3D G3DSA:2.30.130.10 281 372 6.1E-25 T 26-04-2017 IPR015947 PUA-like domain A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 SMART SM00359 284 366 8.2E-17 T 26-04-2017 IPR002478 PUA domain GO:0003723 A4V04_RS11660 262be31d154c25708f709dad60eb1e9f 378 TIGRFAM TIGR01027 proB: glutamate 5-kinase 12 373 2.8E-127 T 26-04-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4V04_RS03990 d4ab1a20e00d520309002fb84dd1aecb 616 Gene3D G3DSA:3.40.50.720 423 554 1.2E-32 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03990 d4ab1a20e00d520309002fb84dd1aecb 616 SUPERFAMILY SSF51735 427 554 5.09E-26 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03990 d4ab1a20e00d520309002fb84dd1aecb 616 Pfam PF00999 Sodium/hydrogen exchanger family 15 386 7.9E-66 T 26-04-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4V04_RS03990 d4ab1a20e00d520309002fb84dd1aecb 616 Pfam PF02254 TrkA-N domain 428 537 9.4E-23 T 26-04-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4V04_RS12995 db690cd4b8262233fa146ec16487fd6a 391 SUPERFAMILY SSF52540 5 143 1.23E-12 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12995 db690cd4b8262233fa146ec16487fd6a 391 Pfam PF13635 Domain of unknown function (DUF4143) 194 348 7.3E-17 T 26-04-2017 IPR025420 Domain of unknown function DUF4143 A4V04_RS12995 db690cd4b8262233fa146ec16487fd6a 391 Pfam PF13173 AAA domain 17 140 7.8E-17 T 26-04-2017 A4V04_RS12995 db690cd4b8262233fa146ec16487fd6a 391 Gene3D G3DSA:3.40.50.300 6 84 1.3E-5 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12995 db690cd4b8262233fa146ec16487fd6a 391 SMART SM00382 15 138 0.0051 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS08665 f39c18b012d019a8a0bb197f931d951c 413 Pfam PF01425 Amidase 44 347 3.1E-43 T 26-04-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4V04_RS08665 f39c18b012d019a8a0bb197f931d951c 413 Gene3D G3DSA:3.90.1300.10 43 408 1.5E-64 T 26-04-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4V04_RS08665 f39c18b012d019a8a0bb197f931d951c 413 SUPERFAMILY SSF75304 17 408 3.92E-55 T 26-04-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4V04_RS01120 758b92c89c2326d1b234756b07329efa 279 Gene3D G3DSA:3.90.226.10 10 221 9.9E-34 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS01120 758b92c89c2326d1b234756b07329efa 279 TIGRFAM TIGR03133 malonate_beta: biotin-independent malonate decarboxylase, beta subunit 5 273 8.3E-109 T 26-04-2017 IPR017556 Biotin-independent malonate decarboxylase, beta subunit GO:0016831|GO:0044262 MetaCyc: PWY-6060 A4V04_RS01120 758b92c89c2326d1b234756b07329efa 279 SUPERFAMILY SSF52096 8 222 5.68E-36 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS01120 758b92c89c2326d1b234756b07329efa 279 Pfam PF01039 Carboxyl transferase domain 12 229 1.3E-16 T 26-04-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4V04_RS08775 d793ce4156dfc3058667ead6896db729 277 Pfam PF01553 Acyltransferase 76 186 8.9E-17 T 26-04-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4V04_RS08775 d793ce4156dfc3058667ead6896db729 277 SUPERFAMILY SSF69593 76 249 2.09E-23 T 26-04-2017 A4V04_RS08775 d793ce4156dfc3058667ead6896db729 277 SMART SM00563 77 189 4.1E-28 T 26-04-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4V04_RS08775 d793ce4156dfc3058667ead6896db729 277 Gene3D G3DSA:3.40.1130.10 78 195 1.3E-5 T 26-04-2017 A4V04_RS11265 a0c8091d2ef45d9549105a749f981102 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 62 16.838 T 26-04-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11265 a0c8091d2ef45d9549105a749f981102 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 7 62 3.4E-18 T 26-04-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11265 a0c8091d2ef45d9549105a749f981102 66 Pfam PF00831 Ribosomal L29 protein 6 62 3.7E-19 T 26-04-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11265 a0c8091d2ef45d9549105a749f981102 66 Gene3D G3DSA:1.10.287.310 5 63 1.4E-20 T 26-04-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11265 a0c8091d2ef45d9549105a749f981102 66 SUPERFAMILY SSF46561 4 63 2.22E-17 T 26-04-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11265 a0c8091d2ef45d9549105a749f981102 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 41 55 - T 26-04-2017 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 239 350 1.1E-21 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 SMART SM00387 239 351 6.2E-36 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 Gene3D G3DSA:1.10.287.130 121 180 1.8E-22 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 SMART SM00388 130 195 1.3E-24 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 Pfam PF00512 His Kinase A (phospho-acceptor) domain 131 193 1.3E-20 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 24 346 3.6E-108 T 26-04-2017 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 348 6.3E-16 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 329 6.3E-16 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 276 290 6.3E-16 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 294 304 6.3E-16 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 Gene3D G3DSA:3.30.450.20 23 89 6.2E-8 T 26-04-2017 A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 SUPERFAMILY SSF47384 117 195 1.57E-22 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 SUPERFAMILY SSF55874 184 349 9.95E-44 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 Gene3D G3DSA:3.30.565.10 181 351 1.2E-45 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS12950 30a8e1fcfe714e9976a264fad9f65777 356 SUPERFAMILY SSF55785 18 88 3.95E-6 T 26-04-2017 IPR000014 PAS domain A4V04_RS10670 30d91d015860879712a4234763121300 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 26-04-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4V04_RS10670 30d91d015860879712a4234763121300 513 Gene3D G3DSA:2.40.30.20 1 93 1.7E-35 T 26-04-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 A4V04_RS10670 30d91d015860879712a4234763121300 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 5.5E-75 T 26-04-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4V04_RS10670 30d91d015860879712a4234763121300 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 2.1E-42 T 26-04-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4V04_RS10670 30d91d015860879712a4234763121300 513 SUPERFAMILY SSF52540 96 381 7.97E-95 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10670 30d91d015860879712a4234763121300 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.649 T 26-04-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 A4V04_RS10670 30d91d015860879712a4234763121300 513 Gene3D G3DSA:3.40.50.300 94 382 1.6E-115 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10670 30d91d015860879712a4234763121300 513 PIRSF PIRSF039088 1 513 1.9E-236 T 26-04-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 A4V04_RS10670 30d91d015860879712a4234763121300 513 SUPERFAMILY SSF50615 10 94 1.69E-29 T 26-04-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4V04_RS10670 30d91d015860879712a4234763121300 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 92 2.0E-16 T 26-04-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4V04_RS10670 30d91d015860879712a4234763121300 513 Gene3D G3DSA:1.20.150.20 383 510 3.4E-45 T 26-04-2017 A4V04_RS10670 30d91d015860879712a4234763121300 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 510 1.1E-247 T 26-04-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 A4V04_RS10670 30d91d015860879712a4234763121300 513 SUPERFAMILY SSF47917 383 510 4.19E-42 T 26-04-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4V04_RS03145 8e8d4e6ff5d72ceae8777229a410aa66 225 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 2.3E-4 T 26-04-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A4V04_RS03145 8e8d4e6ff5d72ceae8777229a410aa66 225 SMART SM00525 186 206 9.0E-5 T 26-04-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A4V04_RS03145 8e8d4e6ff5d72ceae8777229a410aa66 225 Hamap MF_00942 Endonuclease III [nth]. 1 209 35.526 T 26-04-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 A4V04_RS03145 8e8d4e6ff5d72ceae8777229a410aa66 225 PIRSF PIRSF001435 1 212 8.5E-47 T 26-04-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 A4V04_RS03145 8e8d4e6ff5d72ceae8777229a410aa66 225 SUPERFAMILY SSF48150 2 208 2.04E-65 T 26-04-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4V04_RS03145 8e8d4e6ff5d72ceae8777229a410aa66 225 Gene3D G3DSA:1.10.340.30 23 122 1.6E-31 T 26-04-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4V04_RS03145 8e8d4e6ff5d72ceae8777229a410aa66 225 Gene3D G3DSA:1.10.1670.10 123 208 6.1E-34 T 26-04-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A4V04_RS03145 8e8d4e6ff5d72ceae8777229a410aa66 225 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 166 1.4E-17 T 26-04-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4V04_RS03145 8e8d4e6ff5d72ceae8777229a410aa66 225 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 26-04-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A4V04_RS03145 8e8d4e6ff5d72ceae8777229a410aa66 225 SMART SM00478 38 185 9.1E-44 T 26-04-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4V04_RS03145 8e8d4e6ff5d72ceae8777229a410aa66 225 TIGRFAM TIGR01083 nth: endonuclease III 4 194 4.2E-74 T 26-04-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 A4V04_RS09655 374303943e8ebcfbd9565ec11292d7db 205 Pfam PF04961 Formiminotransferase-cyclodeaminase 4 181 6.2E-45 T 26-04-2017 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 A4V04_RS09655 374303943e8ebcfbd9565ec11292d7db 205 SUPERFAMILY SSF101262 4 201 1.19E-38 T 26-04-2017 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 A4V04_RS05685 fdca37422be2de87e219514b48868323 305 Pfam PF03755 YicC-like family, N-terminal region 5 160 4.8E-31 T 26-04-2017 IPR013527 YicC-like, N-terminal A4V04_RS05685 fdca37422be2de87e219514b48868323 305 Pfam PF08340 Domain of unknown function (DUF1732) 222 304 3.2E-32 T 26-04-2017 IPR013551 Domain of unknown function DUF1732 A4V04_RS05685 fdca37422be2de87e219514b48868323 305 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 5 304 5.2E-61 T 26-04-2017 IPR005229 Conserved hypothetical protein CHP00255 A4V04_RS11305 4e6715a199bec7101a5e357b9b5b0c2e 121 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 121 7.9E-35 T 26-04-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11305 4e6715a199bec7101a5e357b9b5b0c2e 121 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 2 121 7.3E-35 T 26-04-2017 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11305 4e6715a199bec7101a5e357b9b5b0c2e 121 Gene3D G3DSA:3.30.420.100 24 121 8.2E-35 T 26-04-2017 A4V04_RS11305 4e6715a199bec7101a5e357b9b5b0c2e 121 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 121 24.966 T 26-04-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11305 4e6715a199bec7101a5e357b9b5b0c2e 121 SUPERFAMILY SSF53137 3 119 1.64E-45 T 26-04-2017 A4V04_RS04495 728f5f9f37a31c61e8104545d49d0928 316 Gene3D G3DSA:3.40.50.620 135 296 1.2E-24 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS04495 728f5f9f37a31c61e8104545d49d0928 316 Gene3D G3DSA:3.40.50.620 2 134 2.9E-29 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS04495 728f5f9f37a31c61e8104545d49d0928 316 SUPERFAMILY SSF52402 1 142 9.21E-26 T 26-04-2017 A4V04_RS04495 728f5f9f37a31c61e8104545d49d0928 316 SUPERFAMILY SSF52402 150 297 1.17E-23 T 26-04-2017 A4V04_RS04495 728f5f9f37a31c61e8104545d49d0928 316 PRINTS PR01438 Universal stress protein signature 257 269 2.6E-7 T 26-04-2017 IPR006015 Universal stress protein A A4V04_RS04495 728f5f9f37a31c61e8104545d49d0928 316 PRINTS PR01438 Universal stress protein signature 275 297 2.6E-7 T 26-04-2017 IPR006015 Universal stress protein A A4V04_RS04495 728f5f9f37a31c61e8104545d49d0928 316 PRINTS PR01438 Universal stress protein signature 149 167 2.6E-7 T 26-04-2017 IPR006015 Universal stress protein A A4V04_RS04495 728f5f9f37a31c61e8104545d49d0928 316 Pfam PF00582 Universal stress protein family 2 140 8.3E-23 T 26-04-2017 IPR006016 UspA GO:0006950 A4V04_RS04495 728f5f9f37a31c61e8104545d49d0928 316 Pfam PF00582 Universal stress protein family 151 297 4.6E-17 T 26-04-2017 IPR006016 UspA GO:0006950 A4V04_RS09580 f197facec1af8438e4e536d965159fa1 508 SUPERFAMILY SSF56425 301 448 1.08E-22 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS09580 f197facec1af8438e4e536d965159fa1 508 SUPERFAMILY SSF51905 447 504 7.31E-51 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS09580 f197facec1af8438e4e536d965159fa1 508 SUPERFAMILY SSF51905 26 300 7.31E-51 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS09580 f197facec1af8438e4e536d965159fa1 508 Pfam PF00890 FAD binding domain 44 485 1.3E-68 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS09580 f197facec1af8438e4e536d965159fa1 508 Gene3D G3DSA:3.90.700.10 303 439 5.5E-18 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS09580 f197facec1af8438e4e536d965159fa1 508 Gene3D G3DSA:3.50.50.60 444 503 6.4E-89 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS09580 f197facec1af8438e4e536d965159fa1 508 Gene3D G3DSA:3.50.50.60 30 283 6.4E-89 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS09580 f197facec1af8438e4e536d965159fa1 508 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 45 499 2.8E-134 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS04630 f08bf2ddc728bc084c7e49c76a927e46 301 SUPERFAMILY SSF103481 45 149 9.42E-11 T 26-04-2017 A4V04_RS04630 f08bf2ddc728bc084c7e49c76a927e46 301 TIGRFAM TIGR00688 rarD: protein RarD 9 266 8.9E-55 T 26-04-2017 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 A4V04_RS04630 f08bf2ddc728bc084c7e49c76a927e46 301 SUPERFAMILY SSF103481 211 294 9.02E-10 T 26-04-2017 A4V04_RS04630 f08bf2ddc728bc084c7e49c76a927e46 301 Pfam PF00892 EamA-like transporter family 8 148 5.8E-11 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS04630 f08bf2ddc728bc084c7e49c76a927e46 301 Pfam PF00892 EamA-like transporter family 157 290 6.3E-8 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS07320 92673c52366f01e66c829a7a72e7d599 478 Gene3D G3DSA:3.40.640.10 46 258 6.0E-60 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS07320 92673c52366f01e66c829a7a72e7d599 478 SUPERFAMILY SSF53383 2 388 4.62E-108 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS07320 92673c52366f01e66c829a7a72e7d599 478 Pfam PF00155 Aminotransferase class I and II 32 375 2.4E-58 T 26-04-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4V04_RS07320 92673c52366f01e66c829a7a72e7d599 478 Gene3D G3DSA:3.90.1150.10 259 389 1.1E-45 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS00740 c842bfa5fd8c25a346d09cf4e9735e11 466 Gene3D G3DSA:3.80.30.20 62 256 8.6E-29 T 26-04-2017 IPR023404 Radical SAM, alpha/beta horseshoe A4V04_RS00740 c842bfa5fd8c25a346d09cf4e9735e11 466 SMART SM00729 60 281 2.1E-47 T 26-04-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4V04_RS00740 c842bfa5fd8c25a346d09cf4e9735e11 466 Pfam PF06969 HemN C-terminal domain 372 438 1.3E-9 T 26-04-2017 IPR010723 HemN, C-terminal A4V04_RS00740 c842bfa5fd8c25a346d09cf4e9735e11 466 Pfam PF04055 Radical SAM superfamily 65 237 4.0E-17 T 26-04-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 A4V04_RS00740 c842bfa5fd8c25a346d09cf4e9735e11 466 SUPERFAMILY SSF102114 13 453 6.67E-132 T 26-04-2017 A4V04_RS00740 c842bfa5fd8c25a346d09cf4e9735e11 466 PIRSF PIRSF000167 6 463 2.6E-165 T 26-04-2017 IPR004558 Coproporphyrinogen III oxidase, oxygen-independent, HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.99.22 A4V04_RS00740 c842bfa5fd8c25a346d09cf4e9735e11 466 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 14 465 1.1E-169 T 26-04-2017 IPR004558 Coproporphyrinogen III oxidase, oxygen-independent, HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.99.22 A4V04_RS05480 72c3b5c1edfffa1d1d7b060c47e1dd37 463 SUPERFAMILY SSF56425 289 407 6.07E-18 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS05480 72c3b5c1edfffa1d1d7b060c47e1dd37 463 Pfam PF00890 FAD binding domain 32 447 4.8E-60 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS05480 72c3b5c1edfffa1d1d7b060c47e1dd37 463 Gene3D G3DSA:3.90.700.10 291 396 6.9E-16 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS05480 72c3b5c1edfffa1d1d7b060c47e1dd37 463 Gene3D G3DSA:3.50.50.60 28 266 1.3E-77 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS05480 72c3b5c1edfffa1d1d7b060c47e1dd37 463 Gene3D G3DSA:3.50.50.60 403 462 1.3E-77 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS05480 72c3b5c1edfffa1d1d7b060c47e1dd37 463 SUPERFAMILY SSF51905 28 283 5.32E-51 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS05480 72c3b5c1edfffa1d1d7b060c47e1dd37 463 SUPERFAMILY SSF51905 406 463 5.32E-51 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04355 f7c06bd9523fb4a0182d948c2510e798 319 Gene3D G3DSA:3.40.190.10 115 196 8.4E-10 T 26-04-2017 A4V04_RS04355 f7c06bd9523fb4a0182d948c2510e798 319 Pfam PF03466 LysR substrate binding domain 95 299 1.8E-24 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS04355 f7c06bd9523fb4a0182d948c2510e798 319 SUPERFAMILY SSF53850 96 301 1.45E-24 T 26-04-2017 A4V04_RS04355 f7c06bd9523fb4a0182d948c2510e798 319 Gene3D G3DSA:1.10.10.10 9 89 3.2E-14 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04355 f7c06bd9523fb4a0182d948c2510e798 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 2.9E-11 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS04355 f7c06bd9523fb4a0182d948c2510e798 319 SUPERFAMILY SSF46785 5 111 2.22E-13 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS06750 a8231fc7d6c4a212f15ddbe2254d552f 178 Pfam PF00578 AhpC/TSA family 35 154 2.2E-13 T 26-04-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4V04_RS06750 a8231fc7d6c4a212f15ddbe2254d552f 178 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 6 174 8.0E-52 T 26-04-2017 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 A4V04_RS06750 a8231fc7d6c4a212f15ddbe2254d552f 178 ProSitePatterns PS00194 Thioredoxin family active site. 65 83 - T 26-04-2017 IPR017937 Thioredoxin, conserved site GO:0045454 A4V04_RS06750 a8231fc7d6c4a212f15ddbe2254d552f 178 SUPERFAMILY SSF52833 30 177 1.81E-30 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS06750 a8231fc7d6c4a212f15ddbe2254d552f 178 Gene3D G3DSA:3.40.30.10 4 176 3.7E-40 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS02415 74244190e974f70f33ae62c4827b8fcd 599 Pfam PF01609 Transposase DDE domain 244 509 2.8E-11 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS02415 74244190e974f70f33ae62c4827b8fcd 599 SUPERFAMILY SSF53098 183 396 1.97E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS02415 74244190e974f70f33ae62c4827b8fcd 599 SUPERFAMILY SSF53098 448 522 1.97E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS01990 74244190e974f70f33ae62c4827b8fcd 599 Pfam PF01609 Transposase DDE domain 244 509 2.8E-11 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS01990 74244190e974f70f33ae62c4827b8fcd 599 SUPERFAMILY SSF53098 183 396 1.97E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS01990 74244190e974f70f33ae62c4827b8fcd 599 SUPERFAMILY SSF53098 448 522 1.97E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS00815 018a8946c74c1ca100bb532b622e0f62 405 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 4 392 9.6E-128 T 26-04-2017 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 A4V04_RS00815 018a8946c74c1ca100bb532b622e0f62 405 Pfam PF02441 Flavoprotein 7 133 2.2E-40 T 26-04-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4V04_RS00815 018a8946c74c1ca100bb532b622e0f62 405 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 186 366 1.3E-62 T 26-04-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A4V04_RS00815 018a8946c74c1ca100bb532b622e0f62 405 SUPERFAMILY SSF52507 1 181 4.06E-59 T 26-04-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4V04_RS00815 018a8946c74c1ca100bb532b622e0f62 405 Gene3D G3DSA:3.40.50.10300 187 399 1.4E-74 T 26-04-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A4V04_RS00815 018a8946c74c1ca100bb532b622e0f62 405 Gene3D G3DSA:3.40.50.1950 4 186 4.0E-65 T 26-04-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4V04_RS00815 018a8946c74c1ca100bb532b622e0f62 405 SUPERFAMILY SSF102645 180 397 9.55E-67 T 26-04-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A4V04_RS09440 29dda8cabf3410583f173c29bd7da4a0 342 Pfam PF07859 alpha/beta hydrolase fold 109 313 5.8E-44 T 26-04-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 A4V04_RS09440 29dda8cabf3410583f173c29bd7da4a0 342 Gene3D G3DSA:3.40.50.1820 40 339 6.7E-58 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS09440 29dda8cabf3410583f173c29bd7da4a0 342 SUPERFAMILY SSF53474 39 337 3.3E-50 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS06895 cea269d683896381d1384968fdb9642c 93 Pfam PF02699 Preprotein translocase subunit 5 83 2.5E-29 T 26-04-2017 IPR003849 Preprotein translocase YajC A4V04_RS06895 cea269d683896381d1384968fdb9642c 93 SMART SM01323 1 86 1.6E-35 T 26-04-2017 IPR003849 Preprotein translocase YajC A4V04_RS06895 cea269d683896381d1384968fdb9642c 93 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 2 86 8.1E-26 T 26-04-2017 IPR003849 Preprotein translocase YajC A4V04_RS06895 cea269d683896381d1384968fdb9642c 93 PRINTS PR01853 Bacterial YajC preprotein translocase signature 2 22 4.9E-13 T 26-04-2017 IPR003849 Preprotein translocase YajC A4V04_RS06895 cea269d683896381d1384968fdb9642c 93 PRINTS PR01853 Bacterial YajC preprotein translocase signature 22 40 4.9E-13 T 26-04-2017 IPR003849 Preprotein translocase YajC A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.3E-15 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.3E-15 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.3E-15 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.3E-15 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.3E-15 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 Pfam PF00679 Elongation factor G C-terminus 606 692 4.8E-31 T 26-04-2017 IPR000640 Translation elongation factor EFG, V domain A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 Gene3D G3DSA:3.30.230.10 490 604 8.2E-50 T 26-04-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 Hamap MF_00054_B Elongation factor G [fusA]. 6 698 109.596 T 26-04-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 SUPERFAMILY SSF54980 609 696 8.27E-30 T 26-04-2017 IPR009022 Elongation factor G, III-V domain A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 Gene3D G3DSA:3.40.50.300 6 293 4.0E-101 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 Pfam PF14492 Elongation Factor G, domain II 410 484 6.6E-35 T 26-04-2017 IPR009022 Elongation factor G, III-V domain A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 1.2E-64 T 26-04-2017 A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 SMART SM00889 486 604 1.8E-74 T 26-04-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 SUPERFAMILY SSF54980 410 487 1.22E-25 T 26-04-2017 IPR009022 Elongation factor G, III-V domain A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 Gene3D G3DSA:3.30.70.240 605 692 9.1E-35 T 26-04-2017 IPR000640 Translation elongation factor EFG, V domain A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 SUPERFAMILY SSF50447 271 410 3.3E-35 T 26-04-2017 IPR009000 Translation protein, beta-barrel domain A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 26-04-2017 IPR031157 Tr-type G domain, conserved site A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 184 1.9E-30 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 SUPERFAMILY SSF52540 6 288 3.97E-105 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 Pfam PF03144 Elongation factor Tu domain 2 330 397 7.8E-17 T 26-04-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 Gene3D G3DSA:2.40.30.10 311 411 7.8E-38 T 26-04-2017 A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 SMART SM00838 606 694 6.4E-56 T 26-04-2017 IPR000640 Translation elongation factor EFG, V domain A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 699 0.0 T 26-04-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 SUPERFAMILY SSF54211 485 605 4.05E-43 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 Gene3D G3DSA:3.30.70.870 412 486 5.9E-39 T 26-04-2017 A4V04_RS11170 d2af01cd04406aa7aafaaace48b4ca60 700 Pfam PF03764 Elongation factor G, domain IV 485 604 3.5E-48 T 26-04-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4V04_RS02690 83af5ac5bb5c8945faa6b8bf77bc304a 1376 SMART SM00487 132 322 4.5E-26 T 26-04-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4V04_RS02690 83af5ac5bb5c8945faa6b8bf77bc304a 1376 SUPERFAMILY SSF52540 135 647 2.03E-98 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02690 83af5ac5bb5c8945faa6b8bf77bc304a 1376 Pfam PF04408 Helicase associated domain (HA2) 530 616 8.2E-15 T 26-04-2017 IPR007502 Helicase-associated domain GO:0004386 A4V04_RS02690 83af5ac5bb5c8945faa6b8bf77bc304a 1376 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 124 1367 0.0 T 26-04-2017 IPR010222 RNA helicase HrpA GO:0004004 A4V04_RS02690 83af5ac5bb5c8945faa6b8bf77bc304a 1376 Pfam PF00270 DEAD/DEAH box helicase 145 290 2.6E-7 T 26-04-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4V04_RS02690 83af5ac5bb5c8945faa6b8bf77bc304a 1376 SMART SM00847 527 618 7.6E-29 T 26-04-2017 IPR007502 Helicase-associated domain GO:0004386 A4V04_RS02690 83af5ac5bb5c8945faa6b8bf77bc304a 1376 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 632 762 2.7E-12 T 26-04-2017 IPR011709 Domain of unknown function DUF1605 A4V04_RS02690 83af5ac5bb5c8945faa6b8bf77bc304a 1376 Pfam PF11898 Domain of unknown function (DUF3418) 777 1367 9.1E-195 T 26-04-2017 IPR024590 RNA helicase HrpA, C-terminal A4V04_RS02690 83af5ac5bb5c8945faa6b8bf77bc304a 1376 Pfam PF00271 Helicase conserved C-terminal domain 345 466 1.9E-10 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS02690 83af5ac5bb5c8945faa6b8bf77bc304a 1376 Gene3D G3DSA:3.40.50.300 331 486 2.8E-13 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02690 83af5ac5bb5c8945faa6b8bf77bc304a 1376 SMART SM00382 149 433 4.9E-5 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS02690 83af5ac5bb5c8945faa6b8bf77bc304a 1376 Gene3D G3DSA:3.40.50.300 134 290 1.2E-47 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02690 83af5ac5bb5c8945faa6b8bf77bc304a 1376 SMART SM00490 367 467 9.2E-17 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS11285 5628f3a0372ba563e9ca5e5ed188f7f2 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 1.1E-40 T 26-04-2017 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11285 5628f3a0372ba563e9ca5e5ed188f7f2 179 Pfam PF00281 Ribosomal protein L5 26 80 3.1E-27 T 26-04-2017 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11285 5628f3a0372ba563e9ca5e5ed188f7f2 179 PIRSF PIRSF002161 1 179 1.5E-63 T 26-04-2017 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11285 5628f3a0372ba563e9ca5e5ed188f7f2 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 44.33 T 26-04-2017 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11285 5628f3a0372ba563e9ca5e5ed188f7f2 179 SUPERFAMILY SSF55282 3 179 5.89E-78 T 26-04-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11285 5628f3a0372ba563e9ca5e5ed188f7f2 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 26-04-2017 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11285 5628f3a0372ba563e9ca5e5ed188f7f2 179 Gene3D G3DSA:3.30.1440.10 1 179 2.0E-77 T 26-04-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS07215 30d7534b49a6d2d1d026ba1231bb76b2 288 SUPERFAMILY SSF52374 4 246 2.82E-82 T 26-04-2017 A4V04_RS07215 30d7534b49a6d2d1d026ba1231bb76b2 288 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 7 250 5.3E-48 T 26-04-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 A4V04_RS07215 30d7534b49a6d2d1d026ba1231bb76b2 288 PRINTS PR00987 Glutamyl-tRNA synthetase signature 191 199 7.2E-14 T 26-04-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4V04_RS07215 30d7534b49a6d2d1d026ba1231bb76b2 288 PRINTS PR00987 Glutamyl-tRNA synthetase signature 36 49 7.2E-14 T 26-04-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4V04_RS07215 30d7534b49a6d2d1d026ba1231bb76b2 288 PRINTS PR00987 Glutamyl-tRNA synthetase signature 7 19 7.2E-14 T 26-04-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4V04_RS07215 30d7534b49a6d2d1d026ba1231bb76b2 288 PRINTS PR00987 Glutamyl-tRNA synthetase signature 175 185 7.2E-14 T 26-04-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4V04_RS07215 30d7534b49a6d2d1d026ba1231bb76b2 288 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 4 287 38.714 T 26-04-2017 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 A4V04_RS07215 30d7534b49a6d2d1d026ba1231bb76b2 288 Gene3D G3DSA:3.90.800.10 69 175 3.2E-18 T 26-04-2017 A4V04_RS07215 30d7534b49a6d2d1d026ba1231bb76b2 288 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 4 262 4.7E-109 T 26-04-2017 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 A4V04_RS07215 30d7534b49a6d2d1d026ba1231bb76b2 288 Gene3D G3DSA:3.40.50.620 4 68 1.3E-41 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS07215 30d7534b49a6d2d1d026ba1231bb76b2 288 Gene3D G3DSA:3.40.50.620 177 226 1.3E-41 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 Pfam PF03484 tRNA synthetase B5 domain 407 472 3.4E-20 T 26-04-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 Gene3D G3DSA:3.30.70.380 707 804 1.3E-19 T 26-04-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 Pfam PF01588 Putative tRNA binding domain 45 145 9.6E-27 T 26-04-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 804 1.0E-236 T 26-04-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 SUPERFAMILY SSF50249 38 196 2.69E-51 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 SUPERFAMILY SSF54991 699 804 5.89E-16 T 26-04-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 SMART SM00873 212 385 1.4E-80 T 26-04-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 Gene3D G3DSA:3.30.930.10 490 694 4.8E-62 T 26-04-2017 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 SMART SM00896 704 804 1.7E-27 T 26-04-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 Gene3D G3DSA:2.40.50.140 41 154 2.5E-47 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 Gene3D G3DSA:3.50.40.10 202 386 2.7E-72 T 26-04-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 SUPERFAMILY SSF55681 468 693 4.92E-51 T 26-04-2017 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 Pfam PF03147 Ferredoxin-fold anticodon binding domain 704 804 8.6E-19 T 26-04-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 SUPERFAMILY SSF46955 405 476 7.87E-19 T 26-04-2017 IPR009061 Putative DNA-binding domain A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 799 42.582 T 26-04-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 Pfam PF03483 B3/4 domain 213 385 1.5E-60 T 26-04-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 SUPERFAMILY SSF56037 197 388 3.92E-66 T 26-04-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 Gene3D G3DSA:3.30.56.10 1 38 8.3E-24 T 26-04-2017 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 Gene3D G3DSA:3.30.56.10 155 184 8.3E-24 T 26-04-2017 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 Gene3D G3DSA:3.30.56.20 403 476 5.7E-25 T 26-04-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A4V04_RS00170 ec467484505c02f0635507c0548dfdf7 805 SMART SM00874 404 472 4.2E-28 T 26-04-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A4V04_RS00710 985e804a983f4be9895c0cbcaaa2f108 200 Gene3D G3DSA:3.40.30.10 76 192 9.8E-9 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS00710 985e804a983f4be9895c0cbcaaa2f108 200 Pfam PF13098 Thioredoxin-like domain 57 175 9.1E-9 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS00710 985e804a983f4be9895c0cbcaaa2f108 200 Gene3D G3DSA:3.40.30.10 7 75 8.4E-4 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS00710 985e804a983f4be9895c0cbcaaa2f108 200 SUPERFAMILY SSF52833 46 191 2.39E-10 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS01025 fe29454299fdb0cf3184683b7ed894a5 198 SUPERFAMILY SSF102198 3 196 1.83E-38 T 26-04-2017 A4V04_RS01025 fe29454299fdb0cf3184683b7ed894a5 198 Gene3D G3DSA:3.50.30.50 3 196 4.4E-38 T 26-04-2017 A4V04_RS01025 fe29454299fdb0cf3184683b7ed894a5 198 Pfam PF04199 Putative cyclase 7 140 5.8E-13 T 26-04-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 A4V04_RS03840 9f577b4d051e0686f360079c8d90031b 253 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 9 215 35.328 T 26-04-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 A4V04_RS03840 9f577b4d051e0686f360079c8d90031b 253 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 10 217 6.1E-67 T 26-04-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 A4V04_RS03840 9f577b4d051e0686f360079c8d90031b 253 Pfam PF02666 Phosphatidylserine decarboxylase 45 211 5.2E-30 T 26-04-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 A4V04_RS05415 5b9dd5f466894f1608a6416f17fd0c2f 239 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 8 220 2.2E-42 T 26-04-2017 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 A4V04_RS05415 5b9dd5f466894f1608a6416f17fd0c2f 239 SUPERFAMILY SSF53067 8 106 1.34E-21 T 26-04-2017 A4V04_RS05415 5b9dd5f466894f1608a6416f17fd0c2f 239 Pfam PF00814 Glycoprotease family 37 155 6.6E-24 T 26-04-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4V04_RS05415 5b9dd5f466894f1608a6416f17fd0c2f 239 Gene3D G3DSA:3.30.420.40 7 139 1.0E-31 T 26-04-2017 A4V04_RS05415 5b9dd5f466894f1608a6416f17fd0c2f 239 SUPERFAMILY SSF53067 116 218 1.22E-9 T 26-04-2017 A4V04_RS12310 9c52f345c61434d37f8a7ea479204474 441 Pfam PF01551 Peptidase family M23 295 392 1.4E-31 T 26-04-2017 IPR016047 Peptidase M23 A4V04_RS12310 9c52f345c61434d37f8a7ea479204474 441 Gene3D G3DSA:2.70.70.10 253 393 1.6E-44 T 26-04-2017 A4V04_RS12310 9c52f345c61434d37f8a7ea479204474 441 SUPERFAMILY SSF51261 203 393 2.46E-58 T 26-04-2017 IPR011055 Duplicated hybrid motif A4V04_RS02425 f8b2cbb200617d4102fd838ac3c18f05 221 SUPERFAMILY SSF46785 16 72 2.51E-8 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02425 f8b2cbb200617d4102fd838ac3c18f05 221 SUPERFAMILY SSF48008 92 215 3.92E-8 T 26-04-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal A4V04_RS02425 f8b2cbb200617d4102fd838ac3c18f05 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 67 2.7E-6 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS02425 f8b2cbb200617d4102fd838ac3c18f05 221 Gene3D G3DSA:1.10.10.10 22 74 7.7E-10 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02425 f8b2cbb200617d4102fd838ac3c18f05 221 Pfam PF07729 FCD domain 94 215 1.6E-10 T 26-04-2017 IPR011711 GntR, C-terminal A4V04_RS02425 f8b2cbb200617d4102fd838ac3c18f05 221 Gene3D G3DSA:1.20.120.530 93 215 1.2E-8 T 26-04-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal A4V04_RS02425 f8b2cbb200617d4102fd838ac3c18f05 221 SMART SM00895 93 216 8.2E-4 T 26-04-2017 IPR011711 GntR, C-terminal A4V04_RS04695 06b1665cb5be22be8af47f76a141f402 489 SUPERFAMILY SSF52949 1 177 2.59E-22 T 26-04-2017 A4V04_RS04695 06b1665cb5be22be8af47f76a141f402 489 Gene3D G3DSA:3.40.220.10 1 154 8.3E-25 T 26-04-2017 A4V04_RS04695 06b1665cb5be22be8af47f76a141f402 489 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 140 1.2E-15 T 26-04-2017 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4V04_RS04695 06b1665cb5be22be8af47f76a141f402 489 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 340 347 - T 26-04-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4V04_RS04695 06b1665cb5be22be8af47f76a141f402 489 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 489 34.617 T 26-04-2017 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 A4V04_RS04695 06b1665cb5be22be8af47f76a141f402 489 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 179 481 2.2E-117 T 26-04-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4V04_RS04695 06b1665cb5be22be8af47f76a141f402 489 PRINTS PR00481 Cytosol aminopeptidase signature 255 272 1.7E-50 T 26-04-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4V04_RS04695 06b1665cb5be22be8af47f76a141f402 489 PRINTS PR00481 Cytosol aminopeptidase signature 365 380 1.7E-50 T 26-04-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4V04_RS04695 06b1665cb5be22be8af47f76a141f402 489 PRINTS PR00481 Cytosol aminopeptidase signature 277 298 1.7E-50 T 26-04-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4V04_RS04695 06b1665cb5be22be8af47f76a141f402 489 PRINTS PR00481 Cytosol aminopeptidase signature 314 335 1.7E-50 T 26-04-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4V04_RS04695 06b1665cb5be22be8af47f76a141f402 489 PRINTS PR00481 Cytosol aminopeptidase signature 336 356 1.7E-50 T 26-04-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4V04_RS04695 06b1665cb5be22be8af47f76a141f402 489 Gene3D G3DSA:3.40.630.10 166 487 8.1E-131 T 26-04-2017 A4V04_RS04695 06b1665cb5be22be8af47f76a141f402 489 SUPERFAMILY SSF53187 173 487 3.45E-115 T 26-04-2017 A4V04_RS06860 61b19949b97b3717e929fc80dbaba92e 369 Pfam PF01924 Hydrogenase formation hypA family 12 364 4.2E-157 T 26-04-2017 IPR002780 Hydrogenase formation HypD protein GO:0046872 A4V04_RS06860 61b19949b97b3717e929fc80dbaba92e 369 PIRSF PIRSF005622 1 369 2.7E-161 T 26-04-2017 IPR002780 Hydrogenase formation HypD protein GO:0046872 A4V04_RS06860 61b19949b97b3717e929fc80dbaba92e 369 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 2 366 1.0E-149 T 26-04-2017 IPR002780 Hydrogenase formation HypD protein GO:0046872 A4V04_RS07425 53c7ef80179220da3c12a802d58c3c3d 789 Gene3D G3DSA:3.30.870.10 603 785 1.1E-65 T 26-04-2017 A4V04_RS07425 53c7ef80179220da3c12a802d58c3c3d 789 Gene3D G3DSA:3.30.870.10 419 602 3.0E-73 T 26-04-2017 A4V04_RS07425 53c7ef80179220da3c12a802d58c3c3d 789 SUPERFAMILY SSF143724 204 416 2.75E-56 T 26-04-2017 A4V04_RS07425 53c7ef80179220da3c12a802d58c3c3d 789 Pfam PF13090 Polyphosphate kinase C-terminal domain 433 780 1.0E-144 T 26-04-2017 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 A4V04_RS07425 53c7ef80179220da3c12a802d58c3c3d 789 SUPERFAMILY SSF56024 419 596 1.22E-53 T 26-04-2017 A4V04_RS07425 53c7ef80179220da3c12a802d58c3c3d 789 SUPERFAMILY SSF140356 98 201 3.79E-31 T 26-04-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 A4V04_RS07425 53c7ef80179220da3c12a802d58c3c3d 789 Pfam PF02503 Polyphosphate kinase middle domain 215 424 3.2E-58 T 26-04-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 A4V04_RS07425 53c7ef80179220da3c12a802d58c3c3d 789 SUPERFAMILY SSF56024 604 783 8.3E-63 T 26-04-2017 A4V04_RS07425 53c7ef80179220da3c12a802d58c3c3d 789 Gene3D G3DSA:3.30.1840.10 204 403 2.9E-61 T 26-04-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 A4V04_RS07425 53c7ef80179220da3c12a802d58c3c3d 789 Pfam PF13089 Polyphosphate kinase N-terminal domain 101 206 2.0E-31 T 26-04-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 A4V04_RS07425 53c7ef80179220da3c12a802d58c3c3d 789 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 101 781 1.3E-246 T 26-04-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A4V04_RS07425 53c7ef80179220da3c12a802d58c3c3d 789 PIRSF PIRSF015589 74 789 8.6E-261 T 26-04-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A4V04_RS07425 53c7ef80179220da3c12a802d58c3c3d 789 Hamap MF_00347 Polyphosphate kinase [ppk]. 98 785 31.196 T 26-04-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A4V04_RS10310 798f109081a22ea14fde66a58cd55010 103 SMART SM00421 51 102 3.3E-8 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10310 798f109081a22ea14fde66a58cd55010 103 Pfam PF00196 Bacterial regulatory proteins, luxR family 53 102 3.8E-13 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10310 798f109081a22ea14fde66a58cd55010 103 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 84 96 3.5E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10310 798f109081a22ea14fde66a58cd55010 103 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 54 68 3.5E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10310 798f109081a22ea14fde66a58cd55010 103 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 68 84 3.5E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10310 798f109081a22ea14fde66a58cd55010 103 Gene3D G3DSA:3.40.50.2300 2 56 3.9E-8 T 26-04-2017 A4V04_RS10310 798f109081a22ea14fde66a58cd55010 103 Gene3D G3DSA:1.10.10.10 57 100 2.4E-16 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10310 798f109081a22ea14fde66a58cd55010 103 ProSitePatterns PS00622 LuxR-type HTH domain signature. 68 95 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10310 798f109081a22ea14fde66a58cd55010 103 SUPERFAMILY SSF52172 2 51 7.47E-7 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS10310 798f109081a22ea14fde66a58cd55010 103 SUPERFAMILY SSF46894 44 101 9.18E-15 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS00685 bb6e58521802dad5246fe4ba13ad0e72 311 Gene3D G3DSA:3.40.630.10 27 113 1.4E-7 T 26-04-2017 A4V04_RS00685 bb6e58521802dad5246fe4ba13ad0e72 311 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 28 304 3.3E-19 T 26-04-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 A4V04_RS00685 bb6e58521802dad5246fe4ba13ad0e72 311 SUPERFAMILY SSF53187 13 306 1.17E-26 T 26-04-2017 A4V04_RS03220 4ae2cae6057fbf610e36b003ecb7fd8a 315 Gene3D G3DSA:3.55.30.10 8 186 1.0E-56 T 26-04-2017 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 A4V04_RS03220 4ae2cae6057fbf610e36b003ecb7fd8a 315 PIRSF PIRSF005261 1 301 2.3E-73 T 26-04-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A4V04_RS03220 4ae2cae6057fbf610e36b003ecb7fd8a 315 SUPERFAMILY SSF64397 10 248 1.96E-57 T 26-04-2017 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 A4V04_RS03220 4ae2cae6057fbf610e36b003ecb7fd8a 315 Pfam PF01430 Hsp33 protein 10 287 7.5E-78 T 26-04-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A4V04_RS03220 4ae2cae6057fbf610e36b003ecb7fd8a 315 Gene3D G3DSA:3.90.1280.10 241 297 2.8E-22 T 26-04-2017 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 A4V04_RS03220 4ae2cae6057fbf610e36b003ecb7fd8a 315 Gene3D G3DSA:1.10.287.480 195 237 1.9E-9 T 26-04-2017 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain A4V04_RS03220 4ae2cae6057fbf610e36b003ecb7fd8a 315 SUPERFAMILY SSF118352 242 297 4.32E-17 T 26-04-2017 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 A4V04_RS01515 8b5f895bcadd34d81821cccc7986ecb3 106 Pfam PF00216 Bacterial DNA-binding protein 1 94 3.0E-28 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS01515 8b5f895bcadd34d81821cccc7986ecb3 106 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 51 70 - T 26-04-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A4V04_RS01515 8b5f895bcadd34d81821cccc7986ecb3 106 SUPERFAMILY SSF47729 1 96 8.1E-28 T 26-04-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4V04_RS01515 8b5f895bcadd34d81821cccc7986ecb3 106 Gene3D G3DSA:4.10.520.10 1 96 1.1E-32 T 26-04-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4V04_RS01515 8b5f895bcadd34d81821cccc7986ecb3 106 PRINTS PR01727 Prokaryotic integration host factor signature 45 60 3.5E-16 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS01515 8b5f895bcadd34d81821cccc7986ecb3 106 PRINTS PR01727 Prokaryotic integration host factor signature 63 76 3.5E-16 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS01515 8b5f895bcadd34d81821cccc7986ecb3 106 PRINTS PR01727 Prokaryotic integration host factor signature 79 93 3.5E-16 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS01515 8b5f895bcadd34d81821cccc7986ecb3 106 SMART SM00411 1 95 5.6E-36 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS09905 ec94aecdd493a0dfeb281edc632dc933 262 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 252 7.3E-73 T 26-04-2017 A4V04_RS09905 ec94aecdd493a0dfeb281edc632dc933 262 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 2 253 7.6E-78 T 26-04-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 A4V04_RS09905 ec94aecdd493a0dfeb281edc632dc933 262 SUPERFAMILY SSF56219 2 254 1.44E-74 T 26-04-2017 IPR005135 Endonuclease/exonuclease/phosphatase A4V04_RS09905 ec94aecdd493a0dfeb281edc632dc933 262 Gene3D G3DSA:3.60.10.10 2 254 3.0E-92 T 26-04-2017 IPR005135 Endonuclease/exonuclease/phosphatase A4V04_RS09905 ec94aecdd493a0dfeb281edc632dc933 262 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 26-04-2017 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 A4V04_RS09905 ec94aecdd493a0dfeb281edc632dc933 262 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 247 1.6E-25 T 26-04-2017 IPR005135 Endonuclease/exonuclease/phosphatase A4V04_RS01105 dae2ee43f67c7de11cd08f01beae4319 550 TIGRFAM TIGR01110 mdcA: malonate decarboxylase, alpha subunit 10 550 2.2E-300 T 26-04-2017 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 A4V04_RS01105 dae2ee43f67c7de11cd08f01beae4319 550 SUPERFAMILY SSF100950 38 276 3.0E-33 T 26-04-2017 A4V04_RS01105 dae2ee43f67c7de11cd08f01beae4319 550 SUPERFAMILY SSF100950 228 492 1.88E-18 T 26-04-2017 A4V04_RS01105 dae2ee43f67c7de11cd08f01beae4319 550 Pfam PF16957 Malonate decarboxylase, alpha subunit, transporter 10 550 5.3E-291 T 26-04-2017 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 A4V04_RS01105 dae2ee43f67c7de11cd08f01beae4319 550 Gene3D G3DSA:3.40.1080.10 39 214 1.5E-10 T 26-04-2017 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 SUPERFAMILY SSF51905 14 324 1.87E-38 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 Gene3D G3DSA:3.50.50.60 12 133 8.3E-41 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 Gene3D G3DSA:3.50.50.60 256 335 8.3E-41 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 301 8.4E-22 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 2.2E-13 T 26-04-2017 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 264 2.2E-13 T 26-04-2017 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 2.2E-13 T 26-04-2017 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 2.2E-13 T 26-04-2017 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 127 1.8E-18 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 285 303 1.8E-18 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 158 182 1.8E-18 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 71 81 1.8E-18 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 14 36 1.8E-18 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 Hamap MF_01685 Ferredoxin--NADP reductase. 12 338 39.834 T 26-04-2017 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101|MetaCyc: PWY-7230 A4V04_RS08555 f44ac1affdd547cad7f240cd0832d7a3 353 Gene3D G3DSA:3.50.50.60 135 253 5.5E-19 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12510 6f276fcd967458bf14c86de3360d530f 858 SUPERFAMILY SSF52540 123 277 2.82E-14 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12510 6f276fcd967458bf14c86de3360d530f 858 SUPERFAMILY SSF52540 306 333 2.82E-14 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12510 6f276fcd967458bf14c86de3360d530f 858 Pfam PF10544 T5orf172 domain 15 108 2.4E-7 T 26-04-2017 IPR018306 Bacteriophage T5, Orf172 DNA-binding A4V04_RS12510 6f276fcd967458bf14c86de3360d530f 858 SMART SM00974 24 111 1.8E-10 T 26-04-2017 IPR018306 Bacteriophage T5, Orf172 DNA-binding A4V04_RS12510 6f276fcd967458bf14c86de3360d530f 858 Gene3D G3DSA:3.40.50.300 125 287 4.0E-7 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12510 6f276fcd967458bf14c86de3360d530f 858 Gene3D G3DSA:3.40.50.300 320 342 4.0E-7 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12510 6f276fcd967458bf14c86de3360d530f 858 Pfam PF04851 Type III restriction enzyme, res subunit 125 283 7.9E-7 T 26-04-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4V04_RS01125 9fb5e6aac6b660d561321a097c698bcc 263 SUPERFAMILY SSF52096 81 232 1.31E-18 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS01125 9fb5e6aac6b660d561321a097c698bcc 263 Pfam PF06833 Malonate decarboxylase gamma subunit (MdcE) 11 263 2.1E-75 T 26-04-2017 IPR011763 Acetyl-coenzyme A carboxyltransferase, C-terminal GO:0016874 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4V04_RS01125 9fb5e6aac6b660d561321a097c698bcc 263 Gene3D G3DSA:3.90.226.10 77 180 3.5E-16 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS01125 9fb5e6aac6b660d561321a097c698bcc 263 TIGRFAM TIGR03134 malonate_gamma: biotin-independent malonate decarboxylase, gamma subunit 33 263 3.1E-89 T 26-04-2017 IPR009648 Biotin-dependent malonate decarboxylase, gamma subunit GO:0044262 MetaCyc: PWY-6060 A4V04_RS05930 3e5ef93073245653feae45a8672f65c2 852 SUPERFAMILY SSF81301 43 149 6.22E-21 T 26-04-2017 A4V04_RS05930 3e5ef93073245653feae45a8672f65c2 852 Pfam PF01909 Nucleotidyltransferase domain 44 115 2.7E-4 T 26-04-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A4V04_RS05930 3e5ef93073245653feae45a8672f65c2 852 SUPERFAMILY SSF55021 778 846 2.6E-9 T 26-04-2017 A4V04_RS05930 3e5ef93073245653feae45a8672f65c2 852 Gene3D G3DSA:3.30.70.260 778 834 2.0E-9 T 26-04-2017 A4V04_RS05930 3e5ef93073245653feae45a8672f65c2 852 SMART SM00471 429 576 0.0013 T 26-04-2017 IPR003607 HD/PDEase domain A4V04_RS05930 3e5ef93073245653feae45a8672f65c2 852 Pfam PF08335 GlnD PII-uridylyltransferase 158 295 6.2E-25 T 26-04-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 A4V04_RS05930 3e5ef93073245653feae45a8672f65c2 852 Gene3D G3DSA:3.30.460.10 54 148 1.5E-6 T 26-04-2017 A4V04_RS05930 3e5ef93073245653feae45a8672f65c2 852 Pfam PF01966 HD domain 434 546 4.4E-8 T 26-04-2017 IPR006674 HD domain A4V04_RS05930 3e5ef93073245653feae45a8672f65c2 852 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 13 828 2.5E-220 T 26-04-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 A4V04_RS05930 3e5ef93073245653feae45a8672f65c2 852 Gene3D G3DSA:1.10.3210.10 404 591 7.0E-20 T 26-04-2017 IPR006674 HD domain A4V04_RS05930 3e5ef93073245653feae45a8672f65c2 852 SUPERFAMILY SSF81891 385 575 3.77E-13 T 26-04-2017 A4V04_RS05930 3e5ef93073245653feae45a8672f65c2 852 PIRSF PIRSF006288 1 852 1.5E-258 T 26-04-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 A4V04_RS05930 3e5ef93073245653feae45a8672f65c2 852 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 852 220.48 T 26-04-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 A4V04_RS08500 267a64a105fe760f893e369017c2e5cf 163 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 14 28 2.4E-6 T 26-04-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A4V04_RS08500 267a64a105fe760f893e369017c2e5cf 163 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 112 121 2.4E-6 T 26-04-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A4V04_RS08500 267a64a105fe760f893e369017c2e5cf 163 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 103 111 2.4E-6 T 26-04-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A4V04_RS08500 267a64a105fe760f893e369017c2e5cf 163 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 11 156 6.6E-39 T 26-04-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A4V04_RS08500 267a64a105fe760f893e369017c2e5cf 163 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 11 157 2.2E-32 T 26-04-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A4V04_RS08500 267a64a105fe760f893e369017c2e5cf 163 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 21 34 - T 26-04-2017 IPR019823 Large-conductance mechanosensitive channel, conserved site A4V04_RS08500 267a64a105fe760f893e369017c2e5cf 163 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 11 160 22.996 T 26-04-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A4V04_RS08500 267a64a105fe760f893e369017c2e5cf 163 SUPERFAMILY SSF81330 21 135 5.49E-32 T 26-04-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A4V04_RS08320 4216e051bc94253aca5b5e9ea26b93a5 281 Pfam PF01844 HNH endonuclease 206 258 1.4E-11 T 26-04-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 A4V04_RS08320 4216e051bc94253aca5b5e9ea26b93a5 281 SMART SM00507 193 254 5.0E-8 T 26-04-2017 IPR003615 HNH nuclease A4V04_RS03140 82a823c778f71c57572d663d0ed0c1fc 252 Pfam PF01564 Spermine/spermidine synthase 44 166 4.7E-6 T 26-04-2017 A4V04_RS03140 82a823c778f71c57572d663d0ed0c1fc 252 Gene3D G3DSA:3.40.50.150 13 240 2.5E-46 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS03140 82a823c778f71c57572d663d0ed0c1fc 252 SUPERFAMILY SSF53335 11 225 2.49E-36 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS11645 4bb39f986a3e6e060769bccf29e99e6a 179 Pfam PF00293 NUDIX domain 7 146 8.3E-23 T 26-04-2017 IPR000086 NUDIX hydrolase domain GO:0016787 A4V04_RS11645 4bb39f986a3e6e060769bccf29e99e6a 179 PRINTS PR00502 NUDIX hydrolase family signature 47 62 1.2E-6 T 26-04-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4V04_RS11645 4bb39f986a3e6e060769bccf29e99e6a 179 PRINTS PR00502 NUDIX hydrolase family signature 33 47 1.2E-6 T 26-04-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4V04_RS11645 4bb39f986a3e6e060769bccf29e99e6a 179 Gene3D G3DSA:3.90.79.10 7 150 2.1E-28 T 26-04-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4V04_RS11645 4bb39f986a3e6e060769bccf29e99e6a 179 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 26-04-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4V04_RS11645 4bb39f986a3e6e060769bccf29e99e6a 179 SUPERFAMILY SSF55811 6 163 3.66E-28 T 26-04-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4V04_RS11645 4bb39f986a3e6e060769bccf29e99e6a 179 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 36.416 T 26-04-2017 IPR022927 RNA pyrophosphohydrolase RppH A4V04_RS00075 4648987351e7420fe599f208c9f6bc40 278 Gene3D G3DSA:3.20.20.140 2 265 1.1E-52 T 26-04-2017 A4V04_RS00075 4648987351e7420fe599f208c9f6bc40 278 SUPERFAMILY SSF51556 4 265 2.18E-54 T 26-04-2017 IPR032466 Metal-dependent hydrolase A4V04_RS00075 4648987351e7420fe599f208c9f6bc40 278 PIRSF PIRSF005902 1 269 4.6E-48 T 26-04-2017 IPR001130 TatD family GO:0016788 A4V04_RS00075 4648987351e7420fe599f208c9f6bc40 278 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 134 144 - T 26-04-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A4V04_RS00075 4648987351e7420fe599f208c9f6bc40 278 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 197 213 - T 26-04-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A4V04_RS00075 4648987351e7420fe599f208c9f6bc40 278 Pfam PF01026 TatD related DNase 5 265 9.3E-43 T 26-04-2017 IPR001130 TatD family GO:0016788 A4V04_RS05425 01efe0d3ecd94d46a8c4de00bf0d8152 290 Gene3D G3DSA:3.40.470.10 103 287 4.6E-59 T 26-04-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4V04_RS05425 01efe0d3ecd94d46a8c4de00bf0d8152 290 SUPERFAMILY SSF52141 102 286 8.5E-54 T 26-04-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4V04_RS05425 01efe0d3ecd94d46a8c4de00bf0d8152 290 SMART SM00986 127 278 4.9E-37 T 26-04-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4V04_RS05425 01efe0d3ecd94d46a8c4de00bf0d8152 290 SMART SM00987 127 278 4.9E-37 T 26-04-2017 A4V04_RS05425 01efe0d3ecd94d46a8c4de00bf0d8152 290 Pfam PF03167 Uracil DNA glycosylase superfamily 127 277 2.4E-42 T 26-04-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4V04_RS05425 01efe0d3ecd94d46a8c4de00bf0d8152 290 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 113 281 6.4E-56 T 26-04-2017 IPR005273 Uracil-DNA glycosylase, family 4 domain A4V04_RS11825 7f88134ef3a852dc12950f3a6cfac3cf 398 Pfam PF00999 Sodium/hydrogen exchanger family 7 386 6.4E-37 T 26-04-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4V04_RS03275 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS03275 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.7E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS03275 1c75f2ef0b82639378a63276f7a4947d 441 SUPERFAMILY SSF56672 7 374 4.67E-51 T 26-04-2017 A4V04_RS03275 1c75f2ef0b82639378a63276f7a4947d 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 1.8E-119 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS04960 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS04960 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.7E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS04960 1c75f2ef0b82639378a63276f7a4947d 441 SUPERFAMILY SSF56672 7 374 4.67E-51 T 26-04-2017 A4V04_RS04960 1c75f2ef0b82639378a63276f7a4947d 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 1.8E-119 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS04330 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS04330 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.7E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS04330 1c75f2ef0b82639378a63276f7a4947d 441 SUPERFAMILY SSF56672 7 374 4.67E-51 T 26-04-2017 A4V04_RS04330 1c75f2ef0b82639378a63276f7a4947d 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 1.8E-119 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS12770 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS12770 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.7E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS12770 1c75f2ef0b82639378a63276f7a4947d 441 SUPERFAMILY SSF56672 7 374 4.67E-51 T 26-04-2017 A4V04_RS12770 1c75f2ef0b82639378a63276f7a4947d 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 1.8E-119 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS05455 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS05455 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.7E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS05455 1c75f2ef0b82639378a63276f7a4947d 441 SUPERFAMILY SSF56672 7 374 4.67E-51 T 26-04-2017 A4V04_RS05455 1c75f2ef0b82639378a63276f7a4947d 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 1.8E-119 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS07145 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS07145 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.7E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS07145 1c75f2ef0b82639378a63276f7a4947d 441 SUPERFAMILY SSF56672 7 374 4.67E-51 T 26-04-2017 A4V04_RS07145 1c75f2ef0b82639378a63276f7a4947d 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 1.8E-119 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS04715 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS04715 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.7E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS04715 1c75f2ef0b82639378a63276f7a4947d 441 SUPERFAMILY SSF56672 7 374 4.67E-51 T 26-04-2017 A4V04_RS04715 1c75f2ef0b82639378a63276f7a4947d 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 1.8E-119 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS12795 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS12795 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.7E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS12795 1c75f2ef0b82639378a63276f7a4947d 441 SUPERFAMILY SSF56672 7 374 4.67E-51 T 26-04-2017 A4V04_RS12795 1c75f2ef0b82639378a63276f7a4947d 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 1.8E-119 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS07575 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS07575 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.7E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS07575 1c75f2ef0b82639378a63276f7a4947d 441 SUPERFAMILY SSF56672 7 374 4.67E-51 T 26-04-2017 A4V04_RS07575 1c75f2ef0b82639378a63276f7a4947d 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 1.8E-119 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS10115 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS10115 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.7E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS10115 1c75f2ef0b82639378a63276f7a4947d 441 SUPERFAMILY SSF56672 7 374 4.67E-51 T 26-04-2017 A4V04_RS10115 1c75f2ef0b82639378a63276f7a4947d 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 1.8E-119 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS08560 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS08560 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.7E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS08560 1c75f2ef0b82639378a63276f7a4947d 441 SUPERFAMILY SSF56672 7 374 4.67E-51 T 26-04-2017 A4V04_RS08560 1c75f2ef0b82639378a63276f7a4947d 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 1.8E-119 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS03090 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS03090 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.7E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS03090 1c75f2ef0b82639378a63276f7a4947d 441 SUPERFAMILY SSF56672 7 374 4.67E-51 T 26-04-2017 A4V04_RS03090 1c75f2ef0b82639378a63276f7a4947d 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 1.8E-119 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS07140 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS07140 1c75f2ef0b82639378a63276f7a4947d 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.7E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS07140 1c75f2ef0b82639378a63276f7a4947d 441 SUPERFAMILY SSF56672 7 374 4.67E-51 T 26-04-2017 A4V04_RS07140 1c75f2ef0b82639378a63276f7a4947d 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 1.8E-119 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS13210 f3c2baadd9800320e4f5d92a7c216878 166 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 48 64 3.1E-23 T 26-04-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A4V04_RS13210 f3c2baadd9800320e4f5d92a7c216878 166 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 3.1E-23 T 26-04-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A4V04_RS13210 f3c2baadd9800320e4f5d92a7c216878 166 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 105 118 3.1E-23 T 26-04-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A4V04_RS13210 f3c2baadd9800320e4f5d92a7c216878 166 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 82 97 3.1E-23 T 26-04-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A4V04_RS13210 f3c2baadd9800320e4f5d92a7c216878 166 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 124 139 3.1E-23 T 26-04-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A4V04_RS13210 f3c2baadd9800320e4f5d92a7c216878 166 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 150 3.4E-41 T 26-04-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily A4V04_RS13210 f3c2baadd9800320e4f5d92a7c216878 166 Gene3D G3DSA:3.40.50.270 2 152 5.3E-54 T 26-04-2017 A4V04_RS13210 f3c2baadd9800320e4f5d92a7c216878 166 SMART SM00226 3 152 2.4E-48 T 26-04-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily A4V04_RS13210 f3c2baadd9800320e4f5d92a7c216878 166 SUPERFAMILY SSF52788 2 153 1.31E-51 T 26-04-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 278 567 1.9E-97 T 26-04-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 491 506 3.7E-22 T 26-04-2017 A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 310 329 3.7E-22 T 26-04-2017 A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 474 489 3.7E-22 T 26-04-2017 A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 527 539 3.7E-22 T 26-04-2017 A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 12 592 1.9E-149 T 26-04-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 SUPERFAMILY SSF52009 123 248 1.96E-22 T 26-04-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 Gene3D G3DSA:1.10.274.10 35 143 1.5E-27 T 26-04-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 Gene3D G3DSA:3.50.30.10 144 271 7.0E-30 T 26-04-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 Pfam PF00391 PEP-utilising enzyme, mobile domain 167 241 2.1E-17 T 26-04-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 Pfam PF05524 PEP-utilising enzyme, N-terminal 14 136 4.7E-23 T 26-04-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 Gene3D G3DSA:3.20.20.60 274 599 3.7E-103 T 26-04-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 SUPERFAMILY SSF47831 35 153 2.09E-24 T 26-04-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 SUPERFAMILY SSF51621 269 575 2.02E-94 T 26-04-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4V04_RS09925 b3bb57d9cffca8052e1108b78d0e3dc2 605 PIRSF PIRSF000732 8 601 9.3E-183 T 26-04-2017 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 A4V04_RS05970 476f25a8e2dbbc977835e738a99de500 297 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 9 292 1.4E-117 T 26-04-2017 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 A4V04_RS05970 476f25a8e2dbbc977835e738a99de500 297 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 202 208 - T 26-04-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4V04_RS05970 476f25a8e2dbbc977835e738a99de500 297 Gene3D G3DSA:1.10.8.10 11 102 3.1E-5 T 26-04-2017 A4V04_RS05970 476f25a8e2dbbc977835e738a99de500 297 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 11 276 8.1E-74 T 26-04-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 A4V04_RS05970 476f25a8e2dbbc977835e738a99de500 297 Pfam PF05175 Methyltransferase small domain 132 215 6.6E-16 T 26-04-2017 IPR007848 Methyltransferase small domain GO:0008168 A4V04_RS05970 476f25a8e2dbbc977835e738a99de500 297 PIRSF PIRSF037167 1 297 1.5E-118 T 26-04-2017 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 A4V04_RS05970 476f25a8e2dbbc977835e738a99de500 297 SUPERFAMILY SSF53335 12 264 4.52E-49 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS05970 476f25a8e2dbbc977835e738a99de500 297 Gene3D G3DSA:3.40.50.150 104 266 4.0E-50 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS05745 bca7a3f2ce06fcae661b4386b23ee87e 164 SUPERFAMILY SSF55021 3 77 3.23E-22 T 26-04-2017 A4V04_RS05745 bca7a3f2ce06fcae661b4386b23ee87e 164 Gene3D G3DSA:3.30.70.1150 84 162 2.5E-30 T 26-04-2017 A4V04_RS05745 bca7a3f2ce06fcae661b4386b23ee87e 164 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 7.0E-32 T 26-04-2017 A4V04_RS05745 bca7a3f2ce06fcae661b4386b23ee87e 164 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 159 7.1E-65 T 26-04-2017 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A4V04_RS05745 bca7a3f2ce06fcae661b4386b23ee87e 164 SUPERFAMILY SSF55021 80 163 4.43E-26 T 26-04-2017 A4V04_RS05745 bca7a3f2ce06fcae661b4386b23ee87e 164 Gene3D G3DSA:3.30.70.260 1 79 2.5E-36 T 26-04-2017 A4V04_RS05745 bca7a3f2ce06fcae661b4386b23ee87e 164 Pfam PF01842 ACT domain 4 69 3.3E-14 T 26-04-2017 IPR002912 ACT domain GO:0008152|GO:0016597 A4V04_RS05745 bca7a3f2ce06fcae661b4386b23ee87e 164 Pfam PF10369 Small subunit of acetolactate synthase 85 158 2.2E-27 T 26-04-2017 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A4V04_RS03530 f2fa7316d6a65875540cb6715f7db424 504 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 13 464 5.5E-114 T 26-04-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 A4V04_RS03530 f2fa7316d6a65875540cb6715f7db424 504 SUPERFAMILY SSF56954 2 467 4.45E-105 T 26-04-2017 A4V04_RS03530 f2fa7316d6a65875540cb6715f7db424 504 Pfam PF02321 Outer membrane efflux protein 65 255 1.9E-25 T 26-04-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A4V04_RS03530 f2fa7316d6a65875540cb6715f7db424 504 Pfam PF02321 Outer membrane efflux protein 283 462 1.7E-23 T 26-04-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A4V04_RS03530 f2fa7316d6a65875540cb6715f7db424 504 Gene3D G3DSA:2.20.200.10 100 142 5.6E-19 T 26-04-2017 A4V04_RS03530 f2fa7316d6a65875540cb6715f7db424 504 Gene3D G3DSA:2.20.200.10 314 349 5.6E-19 T 26-04-2017 A4V04_RS03530 f2fa7316d6a65875540cb6715f7db424 504 Gene3D G3DSA:1.20.1600.10 52 90 3.9E-87 T 26-04-2017 A4V04_RS03530 f2fa7316d6a65875540cb6715f7db424 504 Gene3D G3DSA:1.20.1600.10 351 465 3.9E-87 T 26-04-2017 A4V04_RS03530 f2fa7316d6a65875540cb6715f7db424 504 Gene3D G3DSA:1.20.1600.10 143 313 3.9E-87 T 26-04-2017 A4V04_RS05155 b384f8172c7768d98b1d983626133fa2 185 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 26-04-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4V04_RS05155 b384f8172c7768d98b1d983626133fa2 185 Pfam PF00293 NUDIX domain 42 157 4.5E-18 T 26-04-2017 IPR000086 NUDIX hydrolase domain GO:0016787 A4V04_RS05155 b384f8172c7768d98b1d983626133fa2 185 SUPERFAMILY SSF55811 7 176 7.74E-51 T 26-04-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4V04_RS05155 b384f8172c7768d98b1d983626133fa2 185 Gene3D G3DSA:3.90.79.10 6 176 3.7E-56 T 26-04-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4V04_RS10675 fdec37b94a67d6454cc5faa629b47823 290 Pfam PF00231 ATP synthase 4 288 1.2E-87 T 26-04-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4V04_RS10675 fdec37b94a67d6454cc5faa629b47823 290 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 289 34.577 T 26-04-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4V04_RS10675 fdec37b94a67d6454cc5faa629b47823 290 Gene3D G3DSA:1.10.287.80 204 237 4.9E-41 T 26-04-2017 A4V04_RS10675 fdec37b94a67d6454cc5faa629b47823 290 Gene3D G3DSA:1.10.287.80 19 60 4.9E-41 T 26-04-2017 A4V04_RS10675 fdec37b94a67d6454cc5faa629b47823 290 Gene3D G3DSA:1.10.287.80 238 284 7.3E-30 T 26-04-2017 A4V04_RS10675 fdec37b94a67d6454cc5faa629b47823 290 SUPERFAMILY SSF52943 3 289 1.96E-91 T 26-04-2017 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 A4V04_RS10675 fdec37b94a67d6454cc5faa629b47823 290 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 289 2.9E-102 T 26-04-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4V04_RS10675 fdec37b94a67d6454cc5faa629b47823 290 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 275 288 - T 26-04-2017 IPR023632 ATPase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210 A4V04_RS10675 fdec37b94a67d6454cc5faa629b47823 290 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 6.3E-32 T 26-04-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4V04_RS10675 fdec37b94a67d6454cc5faa629b47823 290 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 6.3E-32 T 26-04-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4V04_RS10675 fdec37b94a67d6454cc5faa629b47823 290 PRINTS PR00126 ATP synthase gamma subunit signature 236 255 6.3E-32 T 26-04-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4V04_RS10675 fdec37b94a67d6454cc5faa629b47823 290 PRINTS PR00126 ATP synthase gamma subunit signature 267 288 6.3E-32 T 26-04-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4V04_RS10675 fdec37b94a67d6454cc5faa629b47823 290 Gene3D G3DSA:3.40.1380.10 64 192 8.1E-36 T 26-04-2017 A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 SUPERFAMILY SSF52540 4 166 1.07E-45 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 7.0E-8 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 73 91 7.0E-8 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 433 1.8E-170 T 26-04-2017 IPR016484 GTP-binding protein EngA GO:0005525 A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 PIRSF PIRSF006485 1 441 4.1E-171 T 26-04-2017 IPR016484 GTP-binding protein EngA GO:0005525 A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 SUPERFAMILY SSF52540 137 439 1.77E-59 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 177 319 3.6E-23 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 157 3.0E-21 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 Pfam PF01926 50S ribosome-binding GTPase 179 297 2.5E-25 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 Pfam PF01926 50S ribosome-binding GTPase 5 120 1.1E-26 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 Hamap MF_00195 GTPase Der [der]. 2 436 37.99 T 26-04-2017 IPR016484 GTP-binding protein EngA GO:0005525 A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 2.1E-25 T 26-04-2017 IPR032859 GTPase Der, C-terminal KH-domain-like A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 Gene3D G3DSA:3.30.300.20 359 435 1.1E-22 T 26-04-2017 IPR015946 K homology domain-like, alpha/beta A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 Gene3D G3DSA:3.40.50.300 177 358 7.2E-49 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00285 60c25d0bdf5e073ecc66cca4fac4a5fa 443 Gene3D G3DSA:3.40.50.300 2 168 7.5E-47 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04755 a568f5fe91aca442e21dfbdb4c5d31bb 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 438 460 1.1E-6 T 26-04-2017 A4V04_RS04755 a568f5fe91aca442e21dfbdb4c5d31bb 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 45 64 1.1E-6 T 26-04-2017 A4V04_RS04755 a568f5fe91aca442e21dfbdb4c5d31bb 496 Pfam PF00890 FAD binding domain 44 472 3.1E-51 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04755 a568f5fe91aca442e21dfbdb4c5d31bb 496 SUPERFAMILY SSF51905 33 294 6.2E-43 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04755 a568f5fe91aca442e21dfbdb4c5d31bb 496 SUPERFAMILY SSF51905 433 493 6.2E-43 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04755 a568f5fe91aca442e21dfbdb4c5d31bb 496 Gene3D G3DSA:3.50.50.60 430 492 1.5E-71 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04755 a568f5fe91aca442e21dfbdb4c5d31bb 496 Gene3D G3DSA:3.50.50.60 30 279 1.5E-71 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04755 a568f5fe91aca442e21dfbdb4c5d31bb 496 SUPERFAMILY SSF56425 303 433 3.28E-17 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04755 a568f5fe91aca442e21dfbdb4c5d31bb 496 Gene3D G3DSA:3.90.700.10 301 423 1.9E-17 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04755 a568f5fe91aca442e21dfbdb4c5d31bb 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 44 66 7.0E-7 T 26-04-2017 A4V04_RS04755 a568f5fe91aca442e21dfbdb4c5d31bb 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 450 465 7.0E-7 T 26-04-2017 A4V04_RS04445 fe66016660497442d46c45d1eff00812 310 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 119 130 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS04445 fe66016660497442d46c45d1eff00812 310 Gene3D G3DSA:3.30.70.20 123 161 2.7E-11 T 26-04-2017 A4V04_RS04445 fe66016660497442d46c45d1eff00812 310 Gene3D G3DSA:3.30.70.20 9 91 3.7E-28 T 26-04-2017 A4V04_RS04445 fe66016660497442d46c45d1eff00812 310 Gene3D G3DSA:3.30.70.20 162 214 3.7E-28 T 26-04-2017 A4V04_RS04445 fe66016660497442d46c45d1eff00812 310 Gene3D G3DSA:3.30.70.20 92 122 1.4E-12 T 26-04-2017 A4V04_RS04445 fe66016660497442d46c45d1eff00812 310 SUPERFAMILY SSF54862 8 274 6.07E-58 T 26-04-2017 A4V04_RS04445 fe66016660497442d46c45d1eff00812 310 Pfam PF13247 4Fe-4S dicluster domain 78 177 1.6E-21 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS04445 fe66016660497442d46c45d1eff00812 310 PIRSF PIRSF036298 1 294 2.4E-74 T 26-04-2017 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 A4V04_RS01550 3978e97390fc86180b73da816babd0c4 164 SMART SM00479 3 164 6.8E-8 T 26-04-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III A4V04_RS01550 3978e97390fc86180b73da816babd0c4 164 Gene3D G3DSA:3.30.420.10 2 163 3.0E-38 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS01550 3978e97390fc86180b73da816babd0c4 164 Pfam PF00929 Exonuclease 6 159 2.9E-16 T 26-04-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III A4V04_RS01550 3978e97390fc86180b73da816babd0c4 164 SUPERFAMILY SSF53098 3 163 2.46E-39 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS03760 6e6244a9f12a2b82393d483174e8e916 443 Pfam PF04932 O-Antigen ligase 226 368 4.6E-19 T 26-04-2017 IPR007016 O-antigen ligase-related A4V04_RS09400 6d3caa139a85a86c8f87fbf38d32943c 298 PIRSF PIRSF000728 16 297 2.6E-104 T 26-04-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4V04_RS09400 6d3caa139a85a86c8f87fbf38d32943c 298 Hamap MF_00082_B Acetylglutamate kinase [argB]. 29 297 35.254 T 26-04-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4V04_RS09400 6d3caa139a85a86c8f87fbf38d32943c 298 TIGRFAM TIGR00761 argB: acetylglutamate kinase 32 272 8.3E-75 T 26-04-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4V04_RS09400 6d3caa139a85a86c8f87fbf38d32943c 298 Pfam PF00696 Amino acid kinase family 31 274 1.3E-44 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS09400 6d3caa139a85a86c8f87fbf38d32943c 298 Gene3D G3DSA:3.40.1160.10 29 296 9.7E-101 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS09400 6d3caa139a85a86c8f87fbf38d32943c 298 SUPERFAMILY SSF53633 13 297 1.18E-88 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 SUPERFAMILY SSF52540 615 913 1.21E-49 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 Gene3D G3DSA:3.40.50.300 2 89 9.6E-55 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 Gene3D G3DSA:3.40.50.300 821 938 2.2E-56 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 Gene3D G3DSA:3.40.50.300 481 601 9.6E-55 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 Gene3D G3DSA:3.40.50.300 607 668 2.2E-56 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 SMART SM00382 633 942 0.0041 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 Gene3D G3DSA:1.20.1580.10 694 820 5.5E-51 T 26-04-2017 A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 Pfam PF00005 ABC transporter 624 860 1.1E-9 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 Gene3D G3DSA:3.30.1490.20 201 248 4.3E-20 T 26-04-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 Gene3D G3DSA:3.30.1490.20 131 154 4.3E-20 T 26-04-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 SUPERFAMILY SSF52540 425 572 8.15E-42 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 SUPERFAMILY SSF52540 2 205 8.15E-42 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 ProSitePatterns PS00211 ABC transporters family signature. 490 504 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 Gene3D G3DSA:1.10.8.280 286 405 1.6E-31 T 26-04-2017 A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 924 0.0 T 26-04-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 Gene3D G3DSA:1.20.1580.10 250 283 1.3E-47 T 26-04-2017 A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 Gene3D G3DSA:1.20.1580.10 92 129 1.3E-47 T 26-04-2017 A4V04_RS08855 9c7069f001a2c15cfd58825cb61b8b9a 947 Gene3D G3DSA:1.20.1580.10 406 480 1.3E-47 T 26-04-2017 A4V04_RS05660 d6068739199ac6220a027dd365482f1b 355 SUPERFAMILY SSF47384 120 191 5.49E-14 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05660 d6068739199ac6220a027dd365482f1b 355 Gene3D G3DSA:3.30.450.20 11 103 4.4E-9 T 26-04-2017 A4V04_RS05660 d6068739199ac6220a027dd365482f1b 355 SUPERFAMILY SSF55874 199 353 9.56E-36 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05660 d6068739199ac6220a027dd365482f1b 355 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 235 354 5.5E-19 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05660 d6068739199ac6220a027dd365482f1b 355 Gene3D G3DSA:3.30.565.10 195 353 4.8E-39 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05660 d6068739199ac6220a027dd365482f1b 355 SMART SM00387 235 355 3.0E-28 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05660 d6068739199ac6220a027dd365482f1b 355 PRINTS PR00344 Bacterial sensor protein C-terminal signature 287 301 1.3E-10 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS05660 d6068739199ac6220a027dd365482f1b 355 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 334 1.3E-10 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS05660 d6068739199ac6220a027dd365482f1b 355 SMART SM00388 130 195 1.1E-12 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05660 d6068739199ac6220a027dd365482f1b 355 Pfam PF00512 His Kinase A (phospho-acceptor) domain 132 189 2.9E-15 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05660 d6068739199ac6220a027dd365482f1b 355 Gene3D G3DSA:1.10.287.130 123 187 3.8E-15 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05660 d6068739199ac6220a027dd365482f1b 355 SUPERFAMILY SSF55785 13 103 1.83E-6 T 26-04-2017 IPR000014 PAS domain A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 Gene3D G3DSA:3.40.228.10 341 410 9.5E-63 T 26-04-2017 A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 Gene3D G3DSA:3.40.228.10 167 279 9.5E-63 T 26-04-2017 A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 18 1023 2.3E-266 T 26-04-2017 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 Gene3D G3DSA:2.40.40.20 819 1023 2.2E-33 T 26-04-2017 A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 SUPERFAMILY SSF53706 19 858 9.16E-232 T 26-04-2017 A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 Gene3D G3DSA:3.40.50.740 81 165 1.5E-50 T 26-04-2017 A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 Gene3D G3DSA:3.40.50.740 411 434 1.5E-50 T 26-04-2017 A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 Gene3D G3DSA:3.40.50.740 520 679 1.5E-50 T 26-04-2017 A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 Gene3D G3DSA:2.20.25.90 21 80 3.9E-18 T 26-04-2017 A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 Pfam PF01568 Molydopterin dinucleotide binding domain 900 972 1.3E-13 T 26-04-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 23 76 9.7E-13 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 Pfam PF00384 Molybdopterin oxidoreductase 79 278 4.2E-19 T 26-04-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 Pfam PF00384 Molybdopterin oxidoreductase 334 645 1.7E-17 T 26-04-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 SUPERFAMILY SSF50692 894 1023 4.75E-30 T 26-04-2017 IPR009010 Aspartate decarboxylase-like domain A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 SUPERFAMILY SSF50692 837 867 4.75E-30 T 26-04-2017 IPR009010 Aspartate decarboxylase-like domain A4V04_RS12140 e0c19a02110dec4f3c8efc1a99f047fc 1060 SMART SM00926 22 76 1.6E-11 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS01395 4419b2e80338ba0e0e86076c341c0e02 386 Pfam PF01420 Type I restriction modification DNA specificity domain 58 183 3.1E-9 T 26-04-2017 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A4V04_RS01395 4419b2e80338ba0e0e86076c341c0e02 386 Pfam PF01420 Type I restriction modification DNA specificity domain 209 346 1.0E-7 T 26-04-2017 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A4V04_RS01395 4419b2e80338ba0e0e86076c341c0e02 386 SUPERFAMILY SSF116734 216 376 1.05E-17 T 26-04-2017 A4V04_RS01395 4419b2e80338ba0e0e86076c341c0e02 386 SUPERFAMILY SSF116734 10 190 4.58E-22 T 26-04-2017 A4V04_RS10385 153fbd68c5cb545db5e69d06a223dc4b 255 Hamap MF_01274 Type III pantothenate kinase [coaX]. 2 254 16.289 T 26-04-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4V04_RS10385 153fbd68c5cb545db5e69d06a223dc4b 255 SUPERFAMILY SSF53067 120 250 1.66E-20 T 26-04-2017 A4V04_RS10385 153fbd68c5cb545db5e69d06a223dc4b 255 Gene3D G3DSA:3.30.420.40 92 254 1.3E-34 T 26-04-2017 A4V04_RS10385 153fbd68c5cb545db5e69d06a223dc4b 255 SUPERFAMILY SSF53067 4 116 3.56E-15 T 26-04-2017 A4V04_RS10385 153fbd68c5cb545db5e69d06a223dc4b 255 Pfam PF03309 Type III pantothenate kinase 4 203 7.4E-36 T 26-04-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4V04_RS10385 153fbd68c5cb545db5e69d06a223dc4b 255 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 4 249 1.5E-18 T 26-04-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4V04_RS06235 dde296ad71a7f2d7df188172c7324243 133 Pfam PF00437 Type II/IV secretion system protein 12 111 8.9E-22 T 26-04-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A4V04_RS06235 dde296ad71a7f2d7df188172c7324243 133 Gene3D G3DSA:3.40.50.300 9 123 1.6E-18 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06235 dde296ad71a7f2d7df188172c7324243 133 SUPERFAMILY SSF52540 6 117 5.31E-14 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 640 4.0E-233 T 26-04-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 Pfam PF01578 Cytochrome C assembly protein 89 295 4.6E-51 T 26-04-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 637 7.3E-127 T 26-04-2017 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 1.0E-93 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 1.0E-93 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 1.0E-93 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 1.0E-93 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 1.0E-93 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 1.0E-93 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 1.0E-93 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 1.0E-93 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 8.9E-59 T 26-04-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 8.9E-59 T 26-04-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 8.9E-59 T 26-04-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 8.9E-59 T 26-04-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 630 643 8.9E-59 T 26-04-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 8.9E-59 T 26-04-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06755 c8d2cb91f41661e380db1fcf0f495d9d 653 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 8.9E-59 T 26-04-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS05845 b2d2891aa5eaeed9d48a8a730719abb0 264 Gene3D G3DSA:1.20.1180.10 193 264 2.7E-16 T 26-04-2017 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 A4V04_RS05845 b2d2891aa5eaeed9d48a8a730719abb0 264 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 264 41.988 T 26-04-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 A4V04_RS05845 b2d2891aa5eaeed9d48a8a730719abb0 264 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 32 64 0.0023 T 26-04-2017 IPR001451 Hexapeptide repeat A4V04_RS05845 b2d2891aa5eaeed9d48a8a730719abb0 264 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 105 139 7.3E-9 T 26-04-2017 IPR001451 Hexapeptide repeat A4V04_RS05845 b2d2891aa5eaeed9d48a8a730719abb0 264 PIRSF PIRSF000456 1 264 6.4E-98 T 26-04-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 A4V04_RS05845 b2d2891aa5eaeed9d48a8a730719abb0 264 SUPERFAMILY SSF51161 2 241 2.83E-71 T 26-04-2017 IPR011004 Trimeric LpxA-like A4V04_RS05845 b2d2891aa5eaeed9d48a8a730719abb0 264 Gene3D G3DSA:2.160.10.10 2 189 4.6E-46 T 26-04-2017 A4V04_RS05845 b2d2891aa5eaeed9d48a8a730719abb0 264 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 176 262 1.2E-18 T 26-04-2017 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 A4V04_RS05845 b2d2891aa5eaeed9d48a8a730719abb0 264 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 4 262 3.0E-93 T 26-04-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 A4V04_RS01165 3374949950ae8bb4dcb03e3a47b60d93 152 Gene3D G3DSA:1.10.10.10 14 93 2.2E-24 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01165 3374949950ae8bb4dcb03e3a47b60d93 152 Pfam PF01475 Ferric uptake regulator family 18 140 6.7E-43 T 26-04-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A4V04_RS01165 3374949950ae8bb4dcb03e3a47b60d93 152 SUPERFAMILY SSF46785 14 145 1.26E-39 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS08695 bd1e3bd250cb45fe1d8fa70e1ecb4773 442 SUPERFAMILY SSF102114 127 373 4.32E-59 T 26-04-2017 A4V04_RS08695 bd1e3bd250cb45fe1d8fa70e1ecb4773 442 Gene3D G3DSA:3.80.30.20 148 381 1.6E-77 T 26-04-2017 IPR023404 Radical SAM, alpha/beta horseshoe A4V04_RS08695 bd1e3bd250cb45fe1d8fa70e1ecb4773 442 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 5 437 5.0E-151 T 26-04-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 A4V04_RS08695 bd1e3bd250cb45fe1d8fa70e1ecb4773 442 Pfam PF00919 Uncharacterized protein family UPF0004 5 105 1.2E-28 T 26-04-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 A4V04_RS08695 bd1e3bd250cb45fe1d8fa70e1ecb4773 442 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 5 440 5.6E-179 T 26-04-2017 A4V04_RS08695 bd1e3bd250cb45fe1d8fa70e1ecb4773 442 Pfam PF04055 Radical SAM superfamily 152 326 1.7E-27 T 26-04-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 A4V04_RS08695 bd1e3bd250cb45fe1d8fa70e1ecb4773 442 SMART SM00729 148 368 3.2E-59 T 26-04-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4V04_RS08695 bd1e3bd250cb45fe1d8fa70e1ecb4773 442 Pfam PF01938 TRAM domain 379 440 8.9E-12 T 26-04-2017 IPR002792 TRAM domain A4V04_RS08695 bd1e3bd250cb45fe1d8fa70e1ecb4773 442 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 4 441 72.175 T 26-04-2017 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 A4V04_RS08695 bd1e3bd250cb45fe1d8fa70e1ecb4773 442 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 152 172 - T 26-04-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 A4V04_RS02090 8d29d6e22fffbc3bdee42e2f0578d15c 302 Gene3D G3DSA:3.90.226.10 232 256 1.5E-14 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS02090 8d29d6e22fffbc3bdee42e2f0578d15c 302 Gene3D G3DSA:3.90.226.10 71 145 1.5E-14 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS02090 8d29d6e22fffbc3bdee42e2f0578d15c 302 SUPERFAMILY SSF52096 67 149 7.07E-16 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS02090 8d29d6e22fffbc3bdee42e2f0578d15c 302 Pfam PF01972 Serine dehydrogenase proteinase 23 172 1.5E-20 T 26-04-2017 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 A4V04_RS05850 dea83690d71d8ff0d3061b499877008b 146 SUPERFAMILY SSF54637 4 141 2.04E-45 T 26-04-2017 IPR029069 HotDog domain A4V04_RS05850 dea83690d71d8ff0d3061b499877008b 146 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 3 141 2.3E-58 T 26-04-2017 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 A4V04_RS05850 dea83690d71d8ff0d3061b499877008b 146 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 144 33.45 T 26-04-2017 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 A4V04_RS05850 dea83690d71d8ff0d3061b499877008b 146 Pfam PF07977 FabA-like domain 11 134 5.1E-36 T 26-04-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 A4V04_RS05850 dea83690d71d8ff0d3061b499877008b 146 Gene3D G3DSA:3.10.129.10 2 142 3.5E-53 T 26-04-2017 IPR029069 HotDog domain A4V04_RS04850 927a17e9775869e7968c45fa52aa3735 231 SUPERFAMILY SSF52402 1 229 1.92E-48 T 26-04-2017 A4V04_RS04850 927a17e9775869e7968c45fa52aa3735 231 Pfam PF06508 Queuosine biosynthesis protein QueC 2 221 1.5E-54 T 26-04-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A4V04_RS04850 927a17e9775869e7968c45fa52aa3735 231 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 1 227 39.42 T 26-04-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A4V04_RS04850 927a17e9775869e7968c45fa52aa3735 231 Gene3D G3DSA:3.40.50.620 1 230 1.1E-62 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS04850 927a17e9775869e7968c45fa52aa3735 231 PIRSF PIRSF006293 1 231 3.8E-60 T 26-04-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A4V04_RS04850 927a17e9775869e7968c45fa52aa3735 231 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 3 214 3.7E-48 T 26-04-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A4V04_RS03830 8a67c8d9aa368cd236141f41c1520bdd 329 SUPERFAMILY SSF51735 2 304 5.04E-32 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03830 8a67c8d9aa368cd236141f41c1520bdd 329 Gene3D G3DSA:3.40.50.720 2 95 8.9E-15 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03830 8a67c8d9aa368cd236141f41c1520bdd 329 Gene3D G3DSA:3.90.25.10 276 306 9.1E-4 T 26-04-2017 A4V04_RS03830 8a67c8d9aa368cd236141f41c1520bdd 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 93 4.2E-9 T 26-04-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4V04_RS03830 8a67c8d9aa368cd236141f41c1520bdd 329 Gene3D G3DSA:3.40.50.720 136 246 6.2E-8 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS02730 d241a1f6f25bf07f0825ced4feb5e4a9 306 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 180 233 4.5E-13 T 26-04-2017 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A4V04_RS02730 d241a1f6f25bf07f0825ced4feb5e4a9 306 SUPERFAMILY SSF55120 10 244 1.07E-83 T 26-04-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS02730 d241a1f6f25bf07f0825ced4feb5e4a9 306 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 243 301 2.4E-11 T 26-04-2017 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS02730 d241a1f6f25bf07f0825ced4feb5e4a9 306 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 32 179 1.1E-60 T 26-04-2017 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A4V04_RS02730 d241a1f6f25bf07f0825ced4feb5e4a9 306 Gene3D G3DSA:2.30.130.10 242 304 2.2E-7 T 26-04-2017 IPR015947 PUA-like domain A4V04_RS02730 d241a1f6f25bf07f0825ced4feb5e4a9 306 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 216 8.7E-80 T 26-04-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS02730 d241a1f6f25bf07f0825ced4feb5e4a9 306 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 10 301 19.288 T 26-04-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS08470 2ca51e41f59cb52ebe55b701556d2f69 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 40.809 T 26-04-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A4V04_RS08470 2ca51e41f59cb52ebe55b701556d2f69 360 SMART SM00937 63 178 6.9E-66 T 26-04-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 A4V04_RS08470 2ca51e41f59cb52ebe55b701556d2f69 360 Pfam PF03462 PCRF domain 13 203 4.9E-75 T 26-04-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 A4V04_RS08470 2ca51e41f59cb52ebe55b701556d2f69 360 Gene3D G3DSA:1.20.58.410 7 93 1.7E-17 T 26-04-2017 A4V04_RS08470 2ca51e41f59cb52ebe55b701556d2f69 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 358 4.1E-166 T 26-04-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A4V04_RS08470 2ca51e41f59cb52ebe55b701556d2f69 360 Gene3D G3DSA:3.30.160.20 214 289 3.8E-34 T 26-04-2017 IPR014720 Double-stranded RNA-binding domain A4V04_RS08470 2ca51e41f59cb52ebe55b701556d2f69 360 Pfam PF00472 RF-1 domain 214 321 5.2E-41 T 26-04-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4V04_RS08470 2ca51e41f59cb52ebe55b701556d2f69 360 SUPERFAMILY SSF75620 12 353 1.44E-137 T 26-04-2017 A4V04_RS06850 bec2e4768d8aa076cb7d08827b948beb 769 Gene3D G3DSA:3.30.70.100 4 91 3.4E-24 T 26-04-2017 A4V04_RS06850 bec2e4768d8aa076cb7d08827b948beb 769 SUPERFAMILY SSF55821 176 406 5.49E-41 T 26-04-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain A4V04_RS06850 bec2e4768d8aa076cb7d08827b948beb 769 Pfam PF00708 Acylphosphatase 7 91 2.6E-19 T 26-04-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A4V04_RS06850 bec2e4768d8aa076cb7d08827b948beb 769 PIRSF PIRSF006256 3 769 2.4E-280 T 26-04-2017 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 A4V04_RS06850 bec2e4768d8aa076cb7d08827b948beb 769 Gene3D G3DSA:3.90.870.10 202 389 3.7E-42 T 26-04-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain A4V04_RS06850 bec2e4768d8aa076cb7d08827b948beb 769 Pfam PF07503 HypF finger 159 191 7.2E-16 T 26-04-2017 IPR011125 Zinc finger, HypF-type GO:0008270 A4V04_RS06850 bec2e4768d8aa076cb7d08827b948beb 769 Pfam PF07503 HypF finger 109 141 4.6E-17 T 26-04-2017 IPR011125 Zinc finger, HypF-type GO:0008270 A4V04_RS06850 bec2e4768d8aa076cb7d08827b948beb 769 ProSitePatterns PS00150 Acylphosphatase signature 1. 12 22 - T 26-04-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A4V04_RS06850 bec2e4768d8aa076cb7d08827b948beb 769 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 10 759 2.8E-241 T 26-04-2017 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 A4V04_RS06850 bec2e4768d8aa076cb7d08827b948beb 769 SUPERFAMILY SSF54975 4 92 4.58E-22 T 26-04-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A4V04_RS06850 bec2e4768d8aa076cb7d08827b948beb 769 Pfam PF01300 Telomere recombination 211 401 2.7E-49 T 26-04-2017 IPR006070 YrdC-like domain GO:0003725 A4V04_RS11945 1cea61345f9b723db2dc73a15bc7fc8e 82 SUPERFAMILY SSF57716 7 63 2.57E-19 T 26-04-2017 A4V04_RS11945 1cea61345f9b723db2dc73a15bc7fc8e 82 Gene3D G3DSA:3.30.50.10 5 62 1.3E-23 T 26-04-2017 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 A4V04_RS11945 1cea61345f9b723db2dc73a15bc7fc8e 82 Pfam PF03884 Domain of unknown function (DUF329) 11 60 5.3E-24 T 26-04-2017 IPR005584 DNA gyrase inhibitor YacG GO:0008270 A4V04_RS11945 1cea61345f9b723db2dc73a15bc7fc8e 82 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 7 68 17.503 T 26-04-2017 IPR005584 DNA gyrase inhibitor YacG GO:0008270 A4V04_RS00925 2f3e30df4adcef6cf19f78c9c2fbe72f 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 7.0E-44 T 26-04-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4V04_RS00925 2f3e30df4adcef6cf19f78c9c2fbe72f 112 PRINTS PR00340 P-II protein signature 23 41 1.4E-42 T 26-04-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4V04_RS00925 2f3e30df4adcef6cf19f78c9c2fbe72f 112 PRINTS PR00340 P-II protein signature 2 17 1.4E-42 T 26-04-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4V04_RS00925 2f3e30df4adcef6cf19f78c9c2fbe72f 112 PRINTS PR00340 P-II protein signature 52 75 1.4E-42 T 26-04-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4V04_RS00925 2f3e30df4adcef6cf19f78c9c2fbe72f 112 PRINTS PR00340 P-II protein signature 83 103 1.4E-42 T 26-04-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4V04_RS00925 2f3e30df4adcef6cf19f78c9c2fbe72f 112 PIRSF PIRSF039144 1 112 2.4E-53 T 26-04-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4V04_RS00925 2f3e30df4adcef6cf19f78c9c2fbe72f 112 Gene3D G3DSA:3.30.70.120 2 112 7.2E-50 T 26-04-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A4V04_RS00925 2f3e30df4adcef6cf19f78c9c2fbe72f 112 SMART SM00938 4 105 3.1E-68 T 26-04-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4V04_RS00925 2f3e30df4adcef6cf19f78c9c2fbe72f 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 26-04-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 A4V04_RS00925 2f3e30df4adcef6cf19f78c9c2fbe72f 112 SUPERFAMILY SSF54913 2 112 9.85E-46 T 26-04-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta A4V04_RS00925 2f3e30df4adcef6cf19f78c9c2fbe72f 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 26-04-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 A4V04_RS07995 849b35a6fb4ce6a6cb6ccba900df2ef5 857 Gene3D G3DSA:3.40.50.740 110 180 1.4E-43 T 26-04-2017 A4V04_RS07995 849b35a6fb4ce6a6cb6ccba900df2ef5 857 Gene3D G3DSA:3.40.50.740 445 693 1.4E-43 T 26-04-2017 A4V04_RS07995 849b35a6fb4ce6a6cb6ccba900df2ef5 857 Pfam PF01568 Molydopterin dinucleotide binding domain 754 804 7.9E-9 T 26-04-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4V04_RS07995 849b35a6fb4ce6a6cb6ccba900df2ef5 857 Gene3D G3DSA:3.40.228.10 181 293 7.7E-42 T 26-04-2017 A4V04_RS07995 849b35a6fb4ce6a6cb6ccba900df2ef5 857 Gene3D G3DSA:3.40.228.10 343 444 7.7E-42 T 26-04-2017 A4V04_RS07995 849b35a6fb4ce6a6cb6ccba900df2ef5 857 SUPERFAMILY SSF53706 360 701 1.23E-113 T 26-04-2017 A4V04_RS07995 849b35a6fb4ce6a6cb6ccba900df2ef5 857 SUPERFAMILY SSF53706 47 332 1.23E-113 T 26-04-2017 A4V04_RS07995 849b35a6fb4ce6a6cb6ccba900df2ef5 857 Gene3D G3DSA:2.40.40.20 710 856 2.6E-13 T 26-04-2017 A4V04_RS07995 849b35a6fb4ce6a6cb6ccba900df2ef5 857 Pfam PF00384 Molybdopterin oxidoreductase 108 604 1.7E-43 T 26-04-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS07995 849b35a6fb4ce6a6cb6ccba900df2ef5 857 Gene3D G3DSA:2.20.25.90 46 109 2.8E-7 T 26-04-2017 A4V04_RS07995 849b35a6fb4ce6a6cb6ccba900df2ef5 857 SUPERFAMILY SSF50692 681 820 2.71E-13 T 26-04-2017 IPR009010 Aspartate decarboxylase-like domain A4V04_RS12030 fc705f247e45c8fb81df5e05781e5fd7 387 Pfam PF00953 Glycosyl transferase family 4 101 310 8.6E-36 T 26-04-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A4V04_RS12030 fc705f247e45c8fb81df5e05781e5fd7 387 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 40 387 2.8E-122 T 26-04-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4V04_RS12030 fc705f247e45c8fb81df5e05781e5fd7 387 ProSitePatterns PS01347 MraY family signature 1. 70 82 - T 26-04-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4V04_RS12030 fc705f247e45c8fb81df5e05781e5fd7 387 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 27 385 23.923 T 26-04-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4V04_RS12030 fc705f247e45c8fb81df5e05781e5fd7 387 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 70 82 1.1E-4 T 26-04-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4V04_RS12030 fc705f247e45c8fb81df5e05781e5fd7 387 ProSitePatterns PS01348 MraY family signature 2. 215 226 - T 26-04-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4V04_RS07815 2ed9a1fea3f210e887348f8a984c498c 615 Pfam PF00672 HAMP domain 174 241 1.2E-8 T 26-04-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4V04_RS07815 2ed9a1fea3f210e887348f8a984c498c 615 SUPERFAMILY SSF158472 193 243 7.32E-9 T 26-04-2017 A4V04_RS07815 2ed9a1fea3f210e887348f8a984c498c 615 Gene3D G3DSA:3.30.565.10 482 612 1.1E-7 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07815 2ed9a1fea3f210e887348f8a984c498c 615 Pfam PF07730 Histidine kinase 414 479 3.2E-15 T 26-04-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4V04_RS07815 2ed9a1fea3f210e887348f8a984c498c 615 PIRSF PIRSF003167 2 615 1.5E-146 T 26-04-2017 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 A4V04_RS07815 2ed9a1fea3f210e887348f8a984c498c 615 SMART SM00387 520 615 2.3E-7 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07815 2ed9a1fea3f210e887348f8a984c498c 615 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 521 597 1.4E-6 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07815 2ed9a1fea3f210e887348f8a984c498c 615 SUPERFAMILY SSF55874 521 612 5.37E-13 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07815 2ed9a1fea3f210e887348f8a984c498c 615 SMART SM00304 193 245 3.1E-8 T 26-04-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4V04_RS07815 2ed9a1fea3f210e887348f8a984c498c 615 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 39 138 2.1E-13 T 26-04-2017 IPR029095 NarX-like, N-terminal A4V04_RS10375 f08af35014e041307244464c8617dbe7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 2.0E-10 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10375 f08af35014e041307244464c8617dbe7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 2.0E-10 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10375 f08af35014e041307244464c8617dbe7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 2.0E-10 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10375 f08af35014e041307244464c8617dbe7 222 SUPERFAMILY SSF52172 7 146 9.68E-32 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS10375 f08af35014e041307244464c8617dbe7 222 Gene3D G3DSA:3.40.50.2300 6 140 5.0E-30 T 26-04-2017 A4V04_RS10375 f08af35014e041307244464c8617dbe7 222 SUPERFAMILY SSF46894 132 199 3.74E-16 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS10375 f08af35014e041307244464c8617dbe7 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 195 9.4E-18 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10375 f08af35014e041307244464c8617dbe7 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10375 f08af35014e041307244464c8617dbe7 222 SMART SM00421 139 196 1.0E-17 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10375 f08af35014e041307244464c8617dbe7 222 SMART SM00448 4 115 6.9E-24 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS10375 f08af35014e041307244464c8617dbe7 222 Pfam PF00072 Response regulator receiver domain 7 115 6.9E-25 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS10375 f08af35014e041307244464c8617dbe7 222 Gene3D G3DSA:1.10.10.10 141 198 1.9E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10415 c8387b28137d498d334ca94b5761f51d 319 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 18 293 4.1E-48 T 26-04-2017 A4V04_RS10415 c8387b28137d498d334ca94b5761f51d 319 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 9 296 18.01 T 26-04-2017 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A4V04_RS10415 c8387b28137d498d334ca94b5761f51d 319 Pfam PF01040 UbiA prenyltransferase family 27 262 3.4E-30 T 26-04-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 A4V04_RS10415 c8387b28137d498d334ca94b5761f51d 319 PIRSF PIRSF005355 2 300 1.8E-71 T 26-04-2017 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 A4V04_RS04840 552bd04243992f370bce700d918a5f14 263 PIRSF PIRSF000094 1 259 4.9E-96 T 26-04-2017 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 A4V04_RS04840 552bd04243992f370bce700d918a5f14 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.4E-5 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS04840 552bd04243992f370bce700d918a5f14 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.4E-5 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS04840 552bd04243992f370bce700d918a5f14 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.4E-5 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS04840 552bd04243992f370bce700d918a5f14 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 253 5.8E-73 T 26-04-2017 A4V04_RS04840 552bd04243992f370bce700d918a5f14 263 Gene3D G3DSA:3.40.50.720 6 202 9.7E-58 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS04840 552bd04243992f370bce700d918a5f14 263 SUPERFAMILY SSF51735 5 253 1.3E-57 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01985 c99973f7f7cd4455fdfba2d32e009a2a 205 SMART SM00421 144 201 1.0E-17 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS01985 c99973f7f7cd4455fdfba2d32e009a2a 205 SMART SM00448 9 120 9.2E-30 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS01985 c99973f7f7cd4455fdfba2d32e009a2a 205 Gene3D G3DSA:3.40.50.2300 11 148 7.2E-34 T 26-04-2017 A4V04_RS01985 c99973f7f7cd4455fdfba2d32e009a2a 205 SUPERFAMILY SSF46894 136 200 9.86E-19 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS01985 c99973f7f7cd4455fdfba2d32e009a2a 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 4.0E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS01985 c99973f7f7cd4455fdfba2d32e009a2a 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 4.0E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS01985 c99973f7f7cd4455fdfba2d32e009a2a 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 4.0E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS01985 c99973f7f7cd4455fdfba2d32e009a2a 205 SUPERFAMILY SSF52172 13 151 2.42E-33 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS01985 c99973f7f7cd4455fdfba2d32e009a2a 205 Gene3D G3DSA:1.10.10.10 149 200 6.2E-22 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01985 c99973f7f7cd4455fdfba2d32e009a2a 205 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 199 9.2E-17 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS01985 c99973f7f7cd4455fdfba2d32e009a2a 205 Pfam PF00072 Response regulator receiver domain 12 120 1.4E-27 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS09555 8a40715e8b281177cbd939372abacd35 487 SUPERFAMILY SSF53067 128 299 4.44E-36 T 26-04-2017 A4V04_RS09555 8a40715e8b281177cbd939372abacd35 487 Gene3D G3DSA:3.30.420.150 123 299 6.8E-41 T 26-04-2017 A4V04_RS09555 8a40715e8b281177cbd939372abacd35 487 Gene3D G3DSA:3.30.420.40 1 120 1.4E-38 T 26-04-2017 A4V04_RS09555 8a40715e8b281177cbd939372abacd35 487 SUPERFAMILY SSF53067 2 122 2.05E-32 T 26-04-2017 A4V04_RS09555 8a40715e8b281177cbd939372abacd35 487 SUPERFAMILY SSF109604 304 485 1.2E-43 T 26-04-2017 A4V04_RS09555 8a40715e8b281177cbd939372abacd35 487 PIRSF PIRSF001267 1 487 2.7E-163 T 26-04-2017 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 A4V04_RS09555 8a40715e8b281177cbd939372abacd35 487 Pfam PF02541 Ppx/GppA phosphatase family 31 298 2.8E-63 T 26-04-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 A4V04_RS06125 503db3f62c52414436ae2916764002ac 224 Gene3D G3DSA:3.40.50.2020 8 212 4.6E-43 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS06125 503db3f62c52414436ae2916764002ac 224 Pfam PF00156 Phosphoribosyl transferase domain 54 179 6.7E-17 T 26-04-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4V04_RS06125 503db3f62c52414436ae2916764002ac 224 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 224 19.153 T 26-04-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4V04_RS06125 503db3f62c52414436ae2916764002ac 224 SUPERFAMILY SSF53271 20 213 4.59E-40 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS07005 a4771d8a600c710b58c0ba0b1a53e387 347 Gene3D G3DSA:3.40.190.10 137 253 2.2E-21 T 26-04-2017 A4V04_RS07005 a4771d8a600c710b58c0ba0b1a53e387 347 Gene3D G3DSA:3.40.190.10 61 136 8.9E-6 T 26-04-2017 A4V04_RS07005 a4771d8a600c710b58c0ba0b1a53e387 347 Pfam PF13379 NMT1-like family 31 272 1.9E-27 T 26-04-2017 A4V04_RS07005 a4771d8a600c710b58c0ba0b1a53e387 347 SMART SM00062 35 264 8.0E-4 T 26-04-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4V04_RS07005 a4771d8a600c710b58c0ba0b1a53e387 347 SUPERFAMILY SSF53850 34 286 4.15E-46 T 26-04-2017 A4V04_RS09110 71fe854157a6762d1272d48e82ea0b7d 358 Pfam PF04348 LppC putative lipoprotein 23 322 1.8E-26 T 26-04-2017 IPR007443 Penicillin-binding protein activator LpoA A4V04_RS09110 71fe854157a6762d1272d48e82ea0b7d 358 Gene3D G3DSA:3.40.50.2300 130 263 2.1E-7 T 26-04-2017 A4V04_RS09110 71fe854157a6762d1272d48e82ea0b7d 358 SUPERFAMILY SSF53822 22 322 1.98E-24 T 26-04-2017 IPR028082 Periplasmic binding protein-like I A4V04_RS09110 71fe854157a6762d1272d48e82ea0b7d 358 Gene3D G3DSA:3.40.50.2300 264 322 7.2E-15 T 26-04-2017 A4V04_RS09110 71fe854157a6762d1272d48e82ea0b7d 358 Gene3D G3DSA:3.40.50.2300 22 127 7.2E-15 T 26-04-2017 A4V04_RS05170 022d9a722859669c557c5c68a01ffeef 345 SUPERFAMILY SSF52540 13 205 2.46E-39 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05170 022d9a722859669c557c5c68a01ffeef 345 Pfam PF13177 DNA polymerase III, delta subunit 20 187 3.8E-38 T 26-04-2017 A4V04_RS05170 022d9a722859669c557c5c68a01ffeef 345 Gene3D G3DSA:3.40.50.300 20 187 4.9E-44 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05170 022d9a722859669c557c5c68a01ffeef 345 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 20 211 3.9E-54 T 26-04-2017 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 SUPERFAMILY SSF52540 45 357 2.34E-87 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 162 1095 0.0 T 26-04-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 SMART SM01058 492 589 2.6E-46 T 26-04-2017 IPR003711 CarD-like/TRCF domain A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 Gene3D G3DSA:3.30.2060.10 146 221 1.2E-14 T 26-04-2017 A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 SUPERFAMILY SSF143517 1007 1157 8.76E-35 T 26-04-2017 A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 SMART SM00490 836 923 3.1E-19 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 Pfam PF02559 CarD-like/TRCF domain 493 588 9.8E-26 T 26-04-2017 IPR003711 CarD-like/TRCF domain A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 Gene3D G3DSA:3.40.50.300 602 799 2.2E-57 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 SUPERFAMILY SSF52540 369 476 3.61E-13 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 Pfam PF00270 DEAD/DEAH box helicase 620 777 7.7E-18 T 26-04-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 Pfam PF03461 TRCF domain 1023 1115 3.2E-24 T 26-04-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 SUPERFAMILY SSF141259 484 561 1.83E-22 T 26-04-2017 IPR003711 CarD-like/TRCF domain A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 Gene3D G3DSA:3.40.50.300 813 969 1.4E-36 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 SMART SM00982 1021 1121 2.0E-35 T 26-04-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 41 1126 28.188 T 26-04-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 SUPERFAMILY SSF52540 796 1000 7.74E-46 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 SMART SM00487 613 803 1.6E-34 T 26-04-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 SUPERFAMILY SSF52540 536 796 2.08E-61 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05430 608f1252e058aa9dd562d3b7b807a549 1158 Pfam PF00271 Helicase conserved C-terminal domain 820 922 1.9E-18 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS02880 9bd131b548eef1ea48733982b0899b06 296 SUPERFAMILY SSF52151 1 104 2.51E-64 T 26-04-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A4V04_RS02880 9bd131b548eef1ea48733982b0899b06 296 SUPERFAMILY SSF52151 172 290 2.51E-64 T 26-04-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A4V04_RS02880 9bd131b548eef1ea48733982b0899b06 296 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 2 273 8.5E-94 T 26-04-2017 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A4V04_RS02880 9bd131b548eef1ea48733982b0899b06 296 PIRSF PIRSF000446 1 293 1.3E-100 T 26-04-2017 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A4V04_RS02880 9bd131b548eef1ea48733982b0899b06 296 Gene3D G3DSA:3.30.70.250 107 178 1.1E-26 T 26-04-2017 A4V04_RS02880 9bd131b548eef1ea48733982b0899b06 296 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 284 1.4E-29 T 26-04-2017 IPR020801 Polyketide synthase, acyl transferase domain A4V04_RS02880 9bd131b548eef1ea48733982b0899b06 296 Gene3D G3DSA:3.40.366.10 179 288 4.1E-61 T 26-04-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 A4V04_RS02880 9bd131b548eef1ea48733982b0899b06 296 Gene3D G3DSA:3.40.366.10 5 104 4.1E-61 T 26-04-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 A4V04_RS02880 9bd131b548eef1ea48733982b0899b06 296 Pfam PF00698 Acyl transferase domain 5 266 6.0E-30 T 26-04-2017 IPR014043 Acyl transferase A4V04_RS02880 9bd131b548eef1ea48733982b0899b06 296 SUPERFAMILY SSF55048 110 179 1.44E-15 T 26-04-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 A4V04_RS10950 0911ef07528f60c97ba4aa490942d246 435 SMART SM00854 4 317 2.2E-53 T 26-04-2017 IPR019079 Capsule synthesis protein, CapA A4V04_RS10950 0911ef07528f60c97ba4aa490942d246 435 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 5 316 1.8E-61 T 26-04-2017 IPR019079 Capsule synthesis protein, CapA A4V04_RS10950 0911ef07528f60c97ba4aa490942d246 435 SUPERFAMILY SSF56300 21 138 3.18E-26 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS10950 0911ef07528f60c97ba4aa490942d246 435 SUPERFAMILY SSF56300 227 326 3.18E-26 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS10950 0911ef07528f60c97ba4aa490942d246 435 Gene3D G3DSA:3.60.21.30 224 323 1.2E-9 T 26-04-2017 A4V04_RS10950 0911ef07528f60c97ba4aa490942d246 435 Gene3D G3DSA:3.60.21.30 25 138 1.2E-9 T 26-04-2017 A4V04_RS07315 b390fe260f82ea1dd5450e1d11f16a02 436 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 26-04-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A4V04_RS07315 b390fe260f82ea1dd5450e1d11f16a02 436 Gene3D G3DSA:3.30.70.260 353 424 1.2E-12 T 26-04-2017 A4V04_RS07315 b390fe260f82ea1dd5450e1d11f16a02 436 Pfam PF00742 Homoserine dehydrogenase 138 316 2.3E-63 T 26-04-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A4V04_RS07315 b390fe260f82ea1dd5450e1d11f16a02 436 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 130 4.0E-20 T 26-04-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A4V04_RS07315 b390fe260f82ea1dd5450e1d11f16a02 436 Gene3D G3DSA:3.40.50.720 3 149 1.2E-47 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS07315 b390fe260f82ea1dd5450e1d11f16a02 436 Pfam PF01842 ACT domain 360 420 1.6E-12 T 26-04-2017 IPR002912 ACT domain GO:0008152|GO:0016597 A4V04_RS07315 b390fe260f82ea1dd5450e1d11f16a02 436 Gene3D G3DSA:3.30.360.10 150 300 3.6E-55 T 26-04-2017 A4V04_RS07315 b390fe260f82ea1dd5450e1d11f16a02 436 SUPERFAMILY SSF55347 138 303 4.71E-51 T 26-04-2017 A4V04_RS07315 b390fe260f82ea1dd5450e1d11f16a02 436 PIRSF PIRSF000098 2 434 7.9E-158 T 26-04-2017 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A4V04_RS07315 b390fe260f82ea1dd5450e1d11f16a02 436 SUPERFAMILY SSF55021 353 424 3.31E-11 T 26-04-2017 A4V04_RS07315 b390fe260f82ea1dd5450e1d11f16a02 436 SUPERFAMILY SSF51735 3 159 2.96E-33 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS11030 ac5259e44de41e258c18e141287a0859 431 SUPERFAMILY SSF103473 9 422 5.75E-32 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS11030 ac5259e44de41e258c18e141287a0859 431 Pfam PF07690 Major Facilitator Superfamily 35 389 1.5E-14 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS11030 ac5259e44de41e258c18e141287a0859 431 Gene3D G3DSA:1.20.1250.20 16 226 4.6E-11 T 26-04-2017 A4V04_RS09705 2661c41f12554dd1bc2960b22593e325 321 SUPERFAMILY SSF53850 97 249 1.52E-11 T 26-04-2017 A4V04_RS09705 2661c41f12554dd1bc2960b22593e325 321 Gene3D G3DSA:3.40.190.10 97 226 3.9E-6 T 26-04-2017 A4V04_RS09705 2661c41f12554dd1bc2960b22593e325 321 SUPERFAMILY SSF46785 8 92 2.55E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09705 2661c41f12554dd1bc2960b22593e325 321 Pfam PF03466 LysR substrate binding domain 97 245 4.7E-9 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS09705 2661c41f12554dd1bc2960b22593e325 321 Gene3D G3DSA:1.10.10.10 8 91 5.4E-21 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09705 2661c41f12554dd1bc2960b22593e325 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 4.4E-15 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09060 bb19208474172b99589da26224a60d54 541 SUPERFAMILY SSF50447 262 392 4.04E-29 T 26-04-2017 IPR009000 Translation protein, beta-barrel domain A4V04_RS09060 bb19208474172b99589da26224a60d54 541 Gene3D G3DSA:3.40.50.300 9 282 7.2E-67 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09060 bb19208474172b99589da26224a60d54 541 Pfam PF03144 Elongation factor Tu domain 2 315 381 8.9E-9 T 26-04-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4V04_RS09060 bb19208474172b99589da26224a60d54 541 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 26-04-2017 IPR031157 Tr-type G domain, conserved site A4V04_RS09060 bb19208474172b99589da26224a60d54 541 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 8 529 2.5E-232 T 26-04-2017 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 A4V04_RS09060 bb19208474172b99589da26224a60d54 541 SUPERFAMILY SSF54980 393 468 4.68E-14 T 26-04-2017 IPR009022 Elongation factor G, III-V domain A4V04_RS09060 bb19208474172b99589da26224a60d54 541 Gene3D G3DSA:3.30.70.870 396 464 7.6E-11 T 26-04-2017 A4V04_RS09060 bb19208474172b99589da26224a60d54 541 SUPERFAMILY SSF52540 12 278 5.81E-86 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09060 bb19208474172b99589da26224a60d54 541 PRINTS PR00315 GTP-binding elongation factor signature 87 97 6.4E-12 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS09060 bb19208474172b99589da26224a60d54 541 PRINTS PR00315 GTP-binding elongation factor signature 67 75 6.4E-12 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS09060 bb19208474172b99589da26224a60d54 541 PRINTS PR00315 GTP-binding elongation factor signature 139 148 6.4E-12 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS09060 bb19208474172b99589da26224a60d54 541 PRINTS PR00315 GTP-binding elongation factor signature 17 30 6.4E-12 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS09060 bb19208474172b99589da26224a60d54 541 PRINTS PR00315 GTP-binding elongation factor signature 103 114 6.4E-12 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS09060 bb19208474172b99589da26224a60d54 541 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 6 527 50.796 T 26-04-2017 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 A4V04_RS09060 bb19208474172b99589da26224a60d54 541 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 18 149 7.0E-21 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS09060 bb19208474172b99589da26224a60d54 541 Pfam PF16658 Class II release factor RF3, C-terminal domain 388 514 1.4E-42 T 26-04-2017 IPR032090 Peptide chain release factor 3, C-terminal A4V04_RS09060 bb19208474172b99589da26224a60d54 541 Gene3D G3DSA:2.40.30.10 293 392 1.5E-25 T 26-04-2017 A4V04_RS09060 bb19208474172b99589da26224a60d54 541 Pfam PF00009 Elongation factor Tu GTP binding domain 15 278 1.8E-51 T 26-04-2017 A4V04_RS07295 b2d2f993d1fee31fea9f70f16fd16cc6 259 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 18 245 3.5E-60 T 26-04-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4V04_RS07295 b2d2f993d1fee31fea9f70f16fd16cc6 259 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 15 256 27.352 T 26-04-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4V04_RS07295 b2d2f993d1fee31fea9f70f16fd16cc6 259 Gene3D G3DSA:3.20.20.70 17 259 9.0E-73 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS07295 b2d2f993d1fee31fea9f70f16fd16cc6 259 SUPERFAMILY SSF51366 7 257 6.5E-58 T 26-04-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A4V04_RS07295 b2d2f993d1fee31fea9f70f16fd16cc6 259 Pfam PF00290 Tryptophan synthase alpha chain 18 252 1.3E-64 T 26-04-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4V04_RS07475 b5c809b3cebd813e780cc4200f192557 286 SUPERFAMILY SSF52374 3 281 4.13E-89 T 26-04-2017 A4V04_RS07475 b5c809b3cebd813e780cc4200f192557 286 Gene3D G3DSA:3.40.50.620 3 171 2.8E-68 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS07475 b5c809b3cebd813e780cc4200f192557 286 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 2 280 4.3E-88 T 26-04-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A4V04_RS07475 b5c809b3cebd813e780cc4200f192557 286 Hamap MF_00158 Pantothenate synthetase [panC]. 2 281 35.803 T 26-04-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A4V04_RS07475 b5c809b3cebd813e780cc4200f192557 286 Pfam PF02569 Pantoate-beta-alanine ligase 3 279 6.2E-91 T 26-04-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A4V04_RS07475 b5c809b3cebd813e780cc4200f192557 286 Gene3D G3DSA:3.30.1300.10 178 281 1.8E-26 T 26-04-2017 A4V04_RS04215 348b9f928b6faaa40adea8762f71edfe 421 ProSitePatterns PS01219 Ammonium transporters signature. 180 205 - T 26-04-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 A4V04_RS04215 348b9f928b6faaa40adea8762f71edfe 421 SUPERFAMILY SSF111352 24 402 1.26E-131 T 26-04-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 A4V04_RS04215 348b9f928b6faaa40adea8762f71edfe 421 TIGRFAM TIGR00836 amt: ammonium transporter 28 418 8.2E-136 T 26-04-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 A4V04_RS04215 348b9f928b6faaa40adea8762f71edfe 421 Gene3D G3DSA:1.10.3430.10 24 402 2.0E-141 T 26-04-2017 IPR029020 Ammonium/urea transporter A4V04_RS04215 348b9f928b6faaa40adea8762f71edfe 421 Pfam PF00909 Ammonium Transporter Family 31 418 1.8E-120 T 26-04-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 A4V04_RS09325 0c3f7150f53be14be9044aeb2ff1960d 381 Gene3D G3DSA:3.40.50.300 3 206 4.2E-77 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09325 0c3f7150f53be14be9044aeb2ff1960d 381 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 187 3.7E-55 T 26-04-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A4V04_RS09325 0c3f7150f53be14be9044aeb2ff1960d 381 SUPERFAMILY SSF90002 286 379 6.02E-24 T 26-04-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4V04_RS09325 0c3f7150f53be14be9044aeb2ff1960d 381 SUPERFAMILY SSF52540 5 208 1.15E-41 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09325 0c3f7150f53be14be9044aeb2ff1960d 381 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 286 379 1.9E-20 T 26-04-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4V04_RS09325 0c3f7150f53be14be9044aeb2ff1960d 381 Gene3D G3DSA:3.30.1220.10 266 380 8.6E-31 T 26-04-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4V04_RS09325 0c3f7150f53be14be9044aeb2ff1960d 381 SMART SM00833 286 379 4.4E-12 T 26-04-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 Pfam PF05192 MutS domain III 283 572 2.9E-36 T 26-04-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 SMART SM00533 296 604 9.6E-84 T 26-04-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 SUPERFAMILY SSF48334 280 576 1.14E-77 T 26-04-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 Gene3D G3DSA:3.40.1170.10 15 131 2.6E-40 T 26-04-2017 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 Gene3D G3DSA:3.40.50.300 580 810 1.9E-77 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 20 874 5.7E-292 T 26-04-2017 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 Pfam PF00488 MutS domain V 622 808 2.2E-79 T 26-04-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 PIRSF PIRSF037677 11 842 1.1E-147 T 26-04-2017 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 Pfam PF05190 MutS family domain IV 441 525 1.1E-26 T 26-04-2017 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 19 868 22.719 T 26-04-2017 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 SUPERFAMILY SSF52540 580 810 5.76E-56 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 Pfam PF01624 MutS domain I 20 130 9.4E-33 T 26-04-2017 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 Pfam PF05188 MutS domain II 140 265 3.1E-20 T 26-04-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 SUPERFAMILY SSF55271 15 126 5.36E-34 T 26-04-2017 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 700 716 - T 26-04-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 Gene3D G3DSA:1.10.1420.10 278 481 1.1E-46 T 26-04-2017 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 SMART SM00534 619 806 1.1E-109 T 26-04-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 Gene3D G3DSA:3.30.420.110 139 268 8.8E-32 T 26-04-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 A4V04_RS03285 85ad0ac391ce1c501141f0b7a684aae5 879 SUPERFAMILY SSF53150 128 293 4.32E-32 T 26-04-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 A4V04_RS11405 f4195be417f259ddc81a630e59b178b6 889 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 6 24 1.8E-4 T 26-04-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A4V04_RS11405 f4195be417f259ddc81a630e59b178b6 889 Gene3D G3DSA:3.40.50.740 107 187 1.2E-39 T 26-04-2017 A4V04_RS11405 f4195be417f259ddc81a630e59b178b6 889 Gene3D G3DSA:3.40.50.740 506 599 1.2E-39 T 26-04-2017 A4V04_RS11405 f4195be417f259ddc81a630e59b178b6 889 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 50 102 1.7E-13 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS11405 f4195be417f259ddc81a630e59b178b6 889 Gene3D G3DSA:3.40.228.10 188 302 1.3E-47 T 26-04-2017 A4V04_RS11405 f4195be417f259ddc81a630e59b178b6 889 Gene3D G3DSA:3.40.228.10 368 505 1.3E-47 T 26-04-2017 A4V04_RS11405 f4195be417f259ddc81a630e59b178b6 889 Pfam PF00384 Molybdopterin oxidoreductase 105 597 1.8E-40 T 26-04-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS11405 f4195be417f259ddc81a630e59b178b6 889 SUPERFAMILY SSF53706 44 568 1.57E-127 T 26-04-2017 A4V04_RS11405 f4195be417f259ddc81a630e59b178b6 889 Gene3D G3DSA:2.20.25.90 46 105 2.2E-20 T 26-04-2017 A4V04_RS11405 f4195be417f259ddc81a630e59b178b6 889 SMART SM00926 48 102 6.6E-16 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS11405 f4195be417f259ddc81a630e59b178b6 889 Gene3D G3DSA:2.40.40.20 715 864 2.8E-38 T 26-04-2017 A4V04_RS11405 f4195be417f259ddc81a630e59b178b6 889 SUPERFAMILY SSF50692 675 859 9.49E-37 T 26-04-2017 IPR009010 Aspartate decarboxylase-like domain A4V04_RS11405 f4195be417f259ddc81a630e59b178b6 889 Pfam PF01568 Molydopterin dinucleotide binding domain 735 838 1.2E-21 T 26-04-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4V04_RS03245 3102ee4a4578329e456e2403987bdf26 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 1.7E-35 T 26-04-2017 IPR002220 DapA-like GO:0008152|GO:0016829 A4V04_RS03245 3102ee4a4578329e456e2403987bdf26 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 1.7E-35 T 26-04-2017 IPR002220 DapA-like GO:0008152|GO:0016829 A4V04_RS03245 3102ee4a4578329e456e2403987bdf26 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 1.7E-35 T 26-04-2017 IPR002220 DapA-like GO:0008152|GO:0016829 A4V04_RS03245 3102ee4a4578329e456e2403987bdf26 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 1.7E-35 T 26-04-2017 IPR002220 DapA-like GO:0008152|GO:0016829 A4V04_RS03245 3102ee4a4578329e456e2403987bdf26 293 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 287 4.4E-110 T 26-04-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS03245 3102ee4a4578329e456e2403987bdf26 293 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 26-04-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS03245 3102ee4a4578329e456e2403987bdf26 293 Gene3D G3DSA:3.20.20.70 1 288 7.7E-116 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS03245 3102ee4a4578329e456e2403987bdf26 293 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 26-04-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS03245 3102ee4a4578329e456e2403987bdf26 293 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 289 65.996 T 26-04-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS03245 3102ee4a4578329e456e2403987bdf26 293 SMART SM01130 1 290 1.0E-139 T 26-04-2017 IPR002220 DapA-like GO:0008152|GO:0016829 A4V04_RS03245 3102ee4a4578329e456e2403987bdf26 293 Pfam PF00701 Dihydrodipicolinate synthetase family 2 288 2.0E-100 T 26-04-2017 IPR002220 DapA-like GO:0008152|GO:0016829 A4V04_RS03245 3102ee4a4578329e456e2403987bdf26 293 SUPERFAMILY SSF51569 2 287 9.11E-101 T 26-04-2017 A4V04_RS03245 3102ee4a4578329e456e2403987bdf26 293 PIRSF PIRSF001365 1 291 5.6E-96 T 26-04-2017 IPR002220 DapA-like GO:0008152|GO:0016829 A4V04_RS07835 07cee0d4ff88910cffd3dbada1ee385e 258 Gene3D G3DSA:3.30.70.20 105 141 6.8E-8 T 26-04-2017 A4V04_RS07835 07cee0d4ff88910cffd3dbada1ee385e 258 Gene3D G3DSA:3.30.70.20 57 104 1.6E-9 T 26-04-2017 A4V04_RS07835 07cee0d4ff88910cffd3dbada1ee385e 258 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 59 70 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS07835 07cee0d4ff88910cffd3dbada1ee385e 258 Pfam PF12838 4Fe-4S dicluster domain 58 113 3.6E-9 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07835 07cee0d4ff88910cffd3dbada1ee385e 258 Pfam PF12838 4Fe-4S dicluster domain 143 195 4.4E-6 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07835 07cee0d4ff88910cffd3dbada1ee385e 258 SUPERFAMILY SSF54862 57 213 8.37E-22 T 26-04-2017 A4V04_RS07835 07cee0d4ff88910cffd3dbada1ee385e 258 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 182 193 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS07835 07cee0d4ff88910cffd3dbada1ee385e 258 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 6 37 9.1E-4 T 26-04-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A4V04_RS07835 07cee0d4ff88910cffd3dbada1ee385e 258 Gene3D G3DSA:3.30.70.20 142 197 4.8E-9 T 26-04-2017 A4V04_RS07835 07cee0d4ff88910cffd3dbada1ee385e 258 PRINTS PR00354 7Fe ferredoxin signature 97 107 6.2E-5 T 26-04-2017 IPR000813 7Fe ferredoxin GO:0009055 A4V04_RS07835 07cee0d4ff88910cffd3dbada1ee385e 258 PRINTS PR00354 7Fe ferredoxin signature 177 194 6.2E-5 T 26-04-2017 IPR000813 7Fe ferredoxin GO:0009055 A4V04_RS07835 07cee0d4ff88910cffd3dbada1ee385e 258 PRINTS PR00354 7Fe ferredoxin signature 145 155 6.2E-5 T 26-04-2017 IPR000813 7Fe ferredoxin GO:0009055 A4V04_RS07835 07cee0d4ff88910cffd3dbada1ee385e 258 TIGRFAM TIGR00397 mauM_napG: MauM/NapG family ferredoxin-type protein 7 212 2.5E-61 T 26-04-2017 IPR004494 MauM/NapG ferredoxin-type protein A4V04_RS09465 399f559fbdf7a2b0ab8bff697d55dfc3 179 Hamap MF_00821 Protein-export protein SecB [secB]. 1 158 29.67 T 26-04-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4V04_RS09465 399f559fbdf7a2b0ab8bff697d55dfc3 179 Gene3D G3DSA:3.10.420.10 11 165 3.5E-52 T 26-04-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4V04_RS09465 399f559fbdf7a2b0ab8bff697d55dfc3 179 Pfam PF02556 Preprotein translocase subunit SecB 12 156 6.3E-49 T 26-04-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4V04_RS09465 399f559fbdf7a2b0ab8bff697d55dfc3 179 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 110 132 1.4E-25 T 26-04-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4V04_RS09465 399f559fbdf7a2b0ab8bff697d55dfc3 179 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 86 106 1.4E-25 T 26-04-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4V04_RS09465 399f559fbdf7a2b0ab8bff697d55dfc3 179 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 20 37 1.4E-25 T 26-04-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4V04_RS09465 399f559fbdf7a2b0ab8bff697d55dfc3 179 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 136 154 1.4E-25 T 26-04-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4V04_RS09465 399f559fbdf7a2b0ab8bff697d55dfc3 179 SUPERFAMILY SSF54611 6 155 5.01E-45 T 26-04-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4V04_RS09465 399f559fbdf7a2b0ab8bff697d55dfc3 179 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 12 156 2.9E-42 T 26-04-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 225 365 3.6E-24 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 Gene3D G3DSA:1.20.120.430 130 190 3.7E-50 T 26-04-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 Gene3D G3DSA:1.20.120.430 257 279 3.7E-50 T 26-04-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 Gene3D G3DSA:1.20.120.430 388 459 3.7E-50 T 26-04-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 PRINTS PR00449 Transforming protein P21 ras signature 335 348 4.9E-6 T 26-04-2017 A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 PRINTS PR00449 Transforming protein P21 ras signature 225 246 4.9E-6 T 26-04-2017 A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 Gene3D G3DSA:3.40.50.300 201 256 1.9E-8 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 Pfam PF12631 MnmE helical domain 131 456 1.8E-53 T 26-04-2017 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 SUPERFAMILY SSF52540 196 377 6.37E-45 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 SUPERFAMILY SSF52540 77 160 6.37E-45 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 13 459 6.5E-103 T 26-04-2017 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 Gene3D G3DSA:3.30.1360.120 5 129 5.1E-39 T 26-04-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 Pfam PF10396 GTP-binding protein TrmE N-terminus 8 128 1.0E-33 T 26-04-2017 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 Pfam PF01926 50S ribosome-binding GTPase 226 345 1.5E-22 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 7 459 31.653 T 26-04-2017 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 A4V04_RS10540 df22cd9f0b4050afa753b01d2ea22aa5 459 Gene3D G3DSA:3.40.50.300 294 386 1.9E-11 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05500 01c899619cc48fd9b09c6fa16a52cbf3 137 Gene3D G3DSA:1.10.260.40 5 79 1.6E-15 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS05500 01c899619cc48fd9b09c6fa16a52cbf3 137 SMART SM00530 14 71 1.8E-11 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS05500 01c899619cc48fd9b09c6fa16a52cbf3 137 SUPERFAMILY SSF47413 10 77 8.73E-14 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS05500 01c899619cc48fd9b09c6fa16a52cbf3 137 Pfam PF01381 Helix-turn-helix 15 71 2.2E-10 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS11790 969586faa74d64e961396d008c8e233d 1223 SMART SM00869 950 1212 5.1E-26 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS11790 969586faa74d64e961396d008c8e233d 1223 SUPERFAMILY SSF103515 917 1223 8.63E-39 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS11790 969586faa74d64e961396d008c8e233d 1223 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 763 1223 5.2E-52 T 26-04-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 A4V04_RS11790 969586faa74d64e961396d008c8e233d 1223 Pfam PF03797 Autotransporter beta-domain 950 1205 4.2E-30 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS11790 969586faa74d64e961396d008c8e233d 1223 Gene3D G3DSA:2.40.128.130 906 1223 4.7E-55 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS05905 777623435ad56af4929fa7cac72f8f98 295 Gene3D G3DSA:1.10.8.10 3 55 3.9E-22 T 26-04-2017 A4V04_RS05905 777623435ad56af4929fa7cac72f8f98 295 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 26-04-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS05905 777623435ad56af4929fa7cac72f8f98 295 Gene3D G3DSA:1.10.286.20 193 236 2.2E-16 T 26-04-2017 A4V04_RS05905 777623435ad56af4929fa7cac72f8f98 295 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 290 1.9E-91 T 26-04-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS05905 777623435ad56af4929fa7cac72f8f98 295 Gene3D G3DSA:3.30.479.20 152 188 7.0E-27 T 26-04-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS05905 777623435ad56af4929fa7cac72f8f98 295 Gene3D G3DSA:3.30.479.20 237 272 7.0E-27 T 26-04-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS05905 777623435ad56af4929fa7cac72f8f98 295 Pfam PF00889 Elongation factor TS 73 273 2.5E-71 T 26-04-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS05905 777623435ad56af4929fa7cac72f8f98 295 Hamap MF_00050 Elongation factor Ts [tsf]. 1 290 75.712 T 26-04-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS05905 777623435ad56af4929fa7cac72f8f98 295 SUPERFAMILY SSF54713 56 146 2.35E-24 T 26-04-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS05905 777623435ad56af4929fa7cac72f8f98 295 Gene3D G3DSA:3.30.479.20 57 146 4.0E-19 T 26-04-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS05905 777623435ad56af4929fa7cac72f8f98 295 SUPERFAMILY SSF46934 3 56 2.14E-14 T 26-04-2017 IPR009060 UBA-like GO:0005515 A4V04_RS05905 777623435ad56af4929fa7cac72f8f98 295 SUPERFAMILY SSF54713 151 290 3.79E-47 T 26-04-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS12250 7c766ae41186276b4ba52f4912814ad0 441 SMART SM00116 288 336 4.0 T 26-04-2017 IPR000644 CBS domain A4V04_RS12250 7c766ae41186276b4ba52f4912814ad0 441 SMART SM00116 224 273 1.7 T 26-04-2017 IPR000644 CBS domain A4V04_RS12250 7c766ae41186276b4ba52f4912814ad0 441 SMART SM01091 350 432 1.5E-29 T 26-04-2017 IPR005170 Transporter-associated domain A4V04_RS12250 7c766ae41186276b4ba52f4912814ad0 441 Pfam PF03471 Transporter associated domain 351 431 6.7E-22 T 26-04-2017 IPR005170 Transporter-associated domain A4V04_RS12250 7c766ae41186276b4ba52f4912814ad0 441 Pfam PF01595 Domain of unknown function DUF21 10 200 1.9E-44 T 26-04-2017 IPR002550 Domain of unknown function DUF21 A4V04_RS12250 7c766ae41186276b4ba52f4912814ad0 441 Gene3D G3DSA:3.30.465.10 329 431 1.8E-27 T 26-04-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4V04_RS12250 7c766ae41186276b4ba52f4912814ad0 441 SUPERFAMILY SSF56176 349 431 1.5E-22 T 26-04-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4V04_RS12250 7c766ae41186276b4ba52f4912814ad0 441 Gene3D G3DSA:3.10.580.10 201 328 4.1E-17 T 26-04-2017 A4V04_RS12250 7c766ae41186276b4ba52f4912814ad0 441 Pfam PF00571 CBS domain 221 271 0.0072 T 26-04-2017 IPR000644 CBS domain A4V04_RS12250 7c766ae41186276b4ba52f4912814ad0 441 Pfam PF00571 CBS domain 288 336 4.5E-6 T 26-04-2017 IPR000644 CBS domain A4V04_RS12250 7c766ae41186276b4ba52f4912814ad0 441 SUPERFAMILY SSF54631 203 339 2.32E-28 T 26-04-2017 A4V04_RS08610 ededbfc95051f4796330b5d7003119c8 519 Gene3D G3DSA:3.40.50.1380 2 186 1.0E-82 T 26-04-2017 IPR011607 Methylglyoxal synthase-like domain A4V04_RS08610 ededbfc95051f4796330b5d7003119c8 519 PIRSF PIRSF000414 1 519 8.7E-214 T 26-04-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS08610 ededbfc95051f4796330b5d7003119c8 519 Pfam PF02142 MGS-like domain 14 129 2.1E-29 T 26-04-2017 IPR011607 Methylglyoxal synthase-like domain A4V04_RS08610 ededbfc95051f4796330b5d7003119c8 519 SUPERFAMILY SSF53927 213 519 8.22E-126 T 26-04-2017 IPR016193 Cytidine deaminase-like GO:0003824 A4V04_RS08610 ededbfc95051f4796330b5d7003119c8 519 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 519 4.2E-213 T 26-04-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS08610 ededbfc95051f4796330b5d7003119c8 519 SUPERFAMILY SSF52335 2 193 6.93E-69 T 26-04-2017 IPR011607 Methylglyoxal synthase-like domain A4V04_RS08610 ededbfc95051f4796330b5d7003119c8 519 SMART SM00851 14 129 2.8E-57 T 26-04-2017 IPR011607 Methylglyoxal synthase-like domain A4V04_RS08610 ededbfc95051f4796330b5d7003119c8 519 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 449 1.9E-120 T 26-04-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS08610 ededbfc95051f4796330b5d7003119c8 519 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 519 44.422 T 26-04-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS08610 ededbfc95051f4796330b5d7003119c8 519 Gene3D G3DSA:3.40.140.20 367 509 5.1E-55 T 26-04-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS08610 ededbfc95051f4796330b5d7003119c8 519 Gene3D G3DSA:3.40.140.20 246 359 1.8E-49 T 26-04-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS08610 ededbfc95051f4796330b5d7003119c8 519 SMART SM00798 134 451 7.3E-198 T 26-04-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS08620 25f4be7cafef6b8d02292bfb33ea9539 235 Pfam PF00483 Nucleotidyl transferase 2 146 1.8E-19 T 26-04-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4V04_RS08620 25f4be7cafef6b8d02292bfb33ea9539 235 Gene3D G3DSA:3.90.550.10 1 228 9.5E-48 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS08620 25f4be7cafef6b8d02292bfb33ea9539 235 SUPERFAMILY SSF53448 1 229 1.08E-48 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS05060 9f42d17a47d2f84daec6192096cdb20d 449 Pfam PF06689 ClpX C4-type zinc finger 9 42 5.5E-5 T 26-04-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A4V04_RS05060 9f42d17a47d2f84daec6192096cdb20d 449 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 1 438 47.439 T 26-04-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A4V04_RS05060 9f42d17a47d2f84daec6192096cdb20d 449 SUPERFAMILY SSF52540 83 425 7.99E-69 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05060 9f42d17a47d2f84daec6192096cdb20d 449 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 8 430 6.7E-178 T 26-04-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A4V04_RS05060 9f42d17a47d2f84daec6192096cdb20d 449 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 340 418 1.4E-11 T 26-04-2017 IPR019489 Clp ATPase, C-terminal A4V04_RS05060 9f42d17a47d2f84daec6192096cdb20d 449 SMART SM00382 136 289 8.7E-10 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS05060 9f42d17a47d2f84daec6192096cdb20d 449 Pfam PF07724 AAA domain (Cdc48 subfamily) 136 334 6.2E-49 T 26-04-2017 IPR003959 ATPase, AAA-type, core GO:0005524 A4V04_RS05060 9f42d17a47d2f84daec6192096cdb20d 449 SMART SM01086 340 433 1.9E-24 T 26-04-2017 IPR019489 Clp ATPase, C-terminal A4V04_RS05060 9f42d17a47d2f84daec6192096cdb20d 449 Gene3D G3DSA:3.40.50.300 317 334 1.7E-48 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05060 9f42d17a47d2f84daec6192096cdb20d 449 Gene3D G3DSA:3.40.50.300 86 278 1.7E-48 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05060 9f42d17a47d2f84daec6192096cdb20d 449 Gene3D G3DSA:1.10.8.60 339 431 9.0E-31 T 26-04-2017 A4V04_RS04750 aac0c76a39a9c4ba244338edee603c3e 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 521 2.1E-5 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS04750 aac0c76a39a9c4ba244338edee603c3e 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 536 554 2.1E-5 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS04750 aac0c76a39a9c4ba244338edee603c3e 579 SMART SM00388 358 428 4.5E-7 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS04750 aac0c76a39a9c4ba244338edee603c3e 579 Gene3D G3DSA:3.40.190.10 48 132 9.4E-4 T 26-04-2017 A4V04_RS04750 aac0c76a39a9c4ba244338edee603c3e 579 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 34 293 1.8E-23 T 26-04-2017 A4V04_RS04750 aac0c76a39a9c4ba244338edee603c3e 579 SMART SM00387 469 576 4.0E-13 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS04750 aac0c76a39a9c4ba244338edee603c3e 579 Gene3D G3DSA:1.10.287.130 361 424 1.2E-5 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS04750 aac0c76a39a9c4ba244338edee603c3e 579 Gene3D G3DSA:3.30.565.10 428 573 1.2E-24 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS04750 aac0c76a39a9c4ba244338edee603c3e 579 SUPERFAMILY SSF53850 48 198 1.59E-10 T 26-04-2017 A4V04_RS04750 aac0c76a39a9c4ba244338edee603c3e 579 Gene3D G3DSA:3.40.190.10 133 254 2.9E-7 T 26-04-2017 A4V04_RS04750 aac0c76a39a9c4ba244338edee603c3e 579 Pfam PF00512 His Kinase A (phospho-acceptor) domain 362 426 2.7E-6 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS04750 aac0c76a39a9c4ba244338edee603c3e 579 SUPERFAMILY SSF55874 432 573 1.2E-23 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS04750 aac0c76a39a9c4ba244338edee603c3e 579 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 473 573 1.6E-12 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS04750 aac0c76a39a9c4ba244338edee603c3e 579 SUPERFAMILY SSF47384 345 428 4.12E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS09715 243bf73cb9e5f5c626559c083715adec 326 Pfam PF03466 LysR substrate binding domain 105 285 1.2E-19 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS09715 243bf73cb9e5f5c626559c083715adec 326 Gene3D G3DSA:1.10.10.10 17 97 1.9E-20 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09715 243bf73cb9e5f5c626559c083715adec 326 SUPERFAMILY SSF46785 20 97 1.56E-15 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09715 243bf73cb9e5f5c626559c083715adec 326 Gene3D G3DSA:3.40.190.10 200 269 4.1E-7 T 26-04-2017 A4V04_RS09715 243bf73cb9e5f5c626559c083715adec 326 SUPERFAMILY SSF53850 103 301 3.67E-21 T 26-04-2017 A4V04_RS09715 243bf73cb9e5f5c626559c083715adec 326 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 19 75 8.8E-17 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09715 243bf73cb9e5f5c626559c083715adec 326 Gene3D G3DSA:3.40.190.10 105 199 5.3E-7 T 26-04-2017 A4V04_RS09715 243bf73cb9e5f5c626559c083715adec 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 1.5E-6 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09715 243bf73cb9e5f5c626559c083715adec 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 1.5E-6 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09715 243bf73cb9e5f5c626559c083715adec 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 1.5E-6 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS04590 f54d9fdd8ac3dd236d4bd078c25bf716 276 PIRSF PIRSF000193 3 267 2.6E-66 T 26-04-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A4V04_RS04590 f54d9fdd8ac3dd236d4bd078c25bf716 276 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 264 2.0E-27 T 26-04-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4V04_RS04590 f54d9fdd8ac3dd236d4bd078c25bf716 276 Gene3D G3DSA:1.10.3730.10 160 264 4.7E-29 T 26-04-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4V04_RS04590 f54d9fdd8ac3dd236d4bd078c25bf716 276 Gene3D G3DSA:3.40.50.720 2 156 2.3E-34 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS04590 f54d9fdd8ac3dd236d4bd078c25bf716 276 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 264 2.3E-69 T 26-04-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A4V04_RS04590 f54d9fdd8ac3dd236d4bd078c25bf716 276 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 264 22.736 T 26-04-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A4V04_RS04590 f54d9fdd8ac3dd236d4bd078c25bf716 276 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 5 98 6.2E-17 T 26-04-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A4V04_RS04590 f54d9fdd8ac3dd236d4bd078c25bf716 276 SUPERFAMILY SSF51735 4 156 9.3E-29 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS04590 f54d9fdd8ac3dd236d4bd078c25bf716 276 SUPERFAMILY SSF48179 160 268 1.21E-28 T 26-04-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4V04_RS02380 8f2f42ca820a5633b40b6c39220d0a7f 206 SUPERFAMILY SSF46894 133 201 2.41E-16 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS02380 8f2f42ca820a5633b40b6c39220d0a7f 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 197 4.8E-16 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02380 8f2f42ca820a5633b40b6c39220d0a7f 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 1.7E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02380 8f2f42ca820a5633b40b6c39220d0a7f 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 1.7E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02380 8f2f42ca820a5633b40b6c39220d0a7f 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 1.7E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02380 8f2f42ca820a5633b40b6c39220d0a7f 206 SUPERFAMILY SSF52172 7 126 1.32E-29 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS02380 8f2f42ca820a5633b40b6c39220d0a7f 206 ProSitePatterns PS00622 LuxR-type HTH domain signature. 158 185 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02380 8f2f42ca820a5633b40b6c39220d0a7f 206 Pfam PF00072 Response regulator receiver domain 7 117 2.9E-25 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS02380 8f2f42ca820a5633b40b6c39220d0a7f 206 SMART SM00421 141 198 6.2E-17 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02380 8f2f42ca820a5633b40b6c39220d0a7f 206 SMART SM00448 5 117 7.3E-29 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS02380 8f2f42ca820a5633b40b6c39220d0a7f 206 Gene3D G3DSA:1.10.10.10 144 200 1.4E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02380 8f2f42ca820a5633b40b6c39220d0a7f 206 Gene3D G3DSA:3.40.50.2300 7 143 3.4E-31 T 26-04-2017 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 Pfam PF00072 Response regulator receiver domain 740 849 6.4E-20 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 Pfam PF00072 Response regulator receiver domain 599 714 3.5E-18 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 Gene3D G3DSA:3.30.450.20 212 329 5.8E-5 T 26-04-2017 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 Gene3D G3DSA:3.40.50.2300 597 717 2.7E-27 T 26-04-2017 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 SMART SM00448 597 714 3.9E-25 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 SMART SM00448 738 856 4.7E-27 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 SUPERFAMILY SSF47384 343 420 1.35E-17 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 SUPERFAMILY SSF55874 408 586 2.1E-43 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 Pfam PF00512 His Kinase A (phospho-acceptor) domain 353 418 2.7E-15 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 SMART SM00387 466 583 8.0E-37 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 Gene3D G3DSA:1.10.287.130 350 415 1.0E-13 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 PRINTS PR00344 Bacterial sensor protein C-terminal signature 567 580 2.7E-16 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 522 2.7E-16 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 561 2.7E-16 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 536 2.7E-16 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 SUPERFAMILY SSF52172 734 859 7.54E-31 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 466 581 2.5E-24 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 SUPERFAMILY SSF52172 597 718 1.57E-28 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 SMART SM00388 353 419 1.9E-18 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 Gene3D G3DSA:3.40.50.2300 735 865 1.1E-34 T 26-04-2017 A4V04_RS02665 6c6c279e1d9e6597efdef92b04e31811 880 Gene3D G3DSA:3.30.565.10 427 581 1.4E-46 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS00005 6ede8f3f6fa5d764ea0815e6b726ebaf 165 Gene3D G3DSA:1.10.287.110 5 72 9.7E-24 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS00005 6ede8f3f6fa5d764ea0815e6b726ebaf 165 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 4 165 17.534 T 26-04-2017 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 Reactome: R-HSA-1268020 A4V04_RS00005 6ede8f3f6fa5d764ea0815e6b726ebaf 165 SUPERFAMILY SSF47144 83 162 1.83E-11 T 26-04-2017 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 A4V04_RS00005 6ede8f3f6fa5d764ea0815e6b726ebaf 165 SUPERFAMILY SSF46565 5 72 7.46E-16 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS00005 6ede8f3f6fa5d764ea0815e6b726ebaf 165 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 16 159 1.0E-26 T 26-04-2017 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 Reactome: R-HSA-1268020 A4V04_RS00005 6ede8f3f6fa5d764ea0815e6b726ebaf 165 Pfam PF00226 DnaJ domain 14 71 1.6E-6 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS00005 6ede8f3f6fa5d764ea0815e6b726ebaf 165 Pfam PF07743 HSCB C-terminal oligomerisation domain 92 164 4.9E-10 T 26-04-2017 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 A4V04_RS00005 6ede8f3f6fa5d764ea0815e6b726ebaf 165 SMART SM00271 4 69 3.9E-7 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS00005 6ede8f3f6fa5d764ea0815e6b726ebaf 165 Gene3D G3DSA:1.20.1280.20 89 163 3.7E-13 T 26-04-2017 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 A4V04_RS03010 17bab74189487111fc7ad1772107c7ae 273 Gene3D G3DSA:1.25.40.10 182 213 1.5E-5 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS03010 17bab74189487111fc7ad1772107c7ae 273 Gene3D G3DSA:1.25.40.10 42 116 1.5E-5 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS03010 17bab74189487111fc7ad1772107c7ae 273 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 13 252 5.5E-76 T 26-04-2017 IPR017689 Outer membrane protein assembly factor BamD A4V04_RS03010 17bab74189487111fc7ad1772107c7ae 273 SUPERFAMILY SSF48452 41 179 7.59E-8 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS03010 17bab74189487111fc7ad1772107c7ae 273 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 8 252 34.254 T 26-04-2017 IPR017689 Outer membrane protein assembly factor BamD A4V04_RS03010 17bab74189487111fc7ad1772107c7ae 273 Pfam PF13525 Outer membrane lipoprotein 42 242 4.6E-62 T 26-04-2017 A4V04_RS05735 ad78efa615cec3b94807b1024088f9e7 214 Pfam PF09335 SNARE associated Golgi protein 50 175 3.0E-19 T 26-04-2017 IPR032816 SNARE associated Golgi protein A4V04_RS11295 989f36f9bc2f797fd2de414ece4487c5 131 Gene3D G3DSA:3.30.1490.10 75 130 1.9E-28 T 26-04-2017 A4V04_RS11295 989f36f9bc2f797fd2de414ece4487c5 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 26-04-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11295 989f36f9bc2f797fd2de414ece4487c5 131 Pfam PF00410 Ribosomal protein S8 5 130 7.6E-49 T 26-04-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11295 989f36f9bc2f797fd2de414ece4487c5 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 31.852 T 26-04-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11295 989f36f9bc2f797fd2de414ece4487c5 131 Gene3D G3DSA:3.30.1370.30 2 72 1.2E-26 T 26-04-2017 A4V04_RS11295 989f36f9bc2f797fd2de414ece4487c5 131 SUPERFAMILY SSF56047 2 130 7.19E-47 T 26-04-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS07745 09f5ad86e2a2f6ef5531421965719496 363 SUPERFAMILY SSF52540 18 228 7.48E-59 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07745 09f5ad86e2a2f6ef5531421965719496 363 SMART SM00382 29 215 1.4E-8 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS07745 09f5ad86e2a2f6ef5531421965719496 363 Gene3D G3DSA:3.40.50.300 22 231 1.5E-54 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07745 09f5ad86e2a2f6ef5531421965719496 363 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 13 360 8.0E-112 T 26-04-2017 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 A4V04_RS07745 09f5ad86e2a2f6ef5531421965719496 363 Gene3D G3DSA:2.40.50.100 285 357 1.1E-15 T 26-04-2017 A4V04_RS07745 09f5ad86e2a2f6ef5531421965719496 363 Pfam PF03459 TOBE domain 298 360 1.6E-11 T 26-04-2017 IPR005116 Transport-associated OB, type 1 A4V04_RS07745 09f5ad86e2a2f6ef5531421965719496 363 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS07745 09f5ad86e2a2f6ef5531421965719496 363 Pfam PF00005 ABC transporter 23 165 5.0E-28 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS07745 09f5ad86e2a2f6ef5531421965719496 363 SUPERFAMILY SSF50331 242 360 7.02E-18 T 26-04-2017 IPR008995 Molybdate/tungstate binding, C-terminal A4V04_RS09230 ebd12fef2963d479b3268b7f2a471654 390 Pfam PF13609 Gram-negative porin 28 366 1.3E-29 T 26-04-2017 A4V04_RS09230 ebd12fef2963d479b3268b7f2a471654 390 SUPERFAMILY SSF56935 33 390 1.07E-45 T 26-04-2017 A4V04_RS09230 ebd12fef2963d479b3268b7f2a471654 390 Gene3D G3DSA:2.40.160.10 33 390 1.0E-55 T 26-04-2017 IPR023614 Porin domain A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 8.7E-41 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 322 8.7E-41 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 8.7E-41 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 8.7E-41 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 8.7E-41 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 Gene3D G3DSA:3.50.50.60 279 342 2.3E-55 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 Gene3D G3DSA:3.50.50.60 2 155 2.3E-55 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 Gene3D G3DSA:3.50.50.60 158 278 3.3E-33 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 Gene3D G3DSA:3.30.390.30 343 470 2.9E-45 T 26-04-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 6.7E-71 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 6.7E-71 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 6.7E-71 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 6.7E-71 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 6.7E-71 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 315 322 6.7E-71 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 6.7E-71 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 6.7E-71 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 6.7E-71 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 335 1.3E-65 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 472 1.6E-154 T 26-04-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 SUPERFAMILY SSF51905 2 345 1.41E-61 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 463 8.2E-36 T 26-04-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 PIRSF PIRSF000350 1 473 5.1E-85 T 26-04-2017 A4V04_RS02990 91f4102744a29926f061bdddce7cb60e 473 SUPERFAMILY SSF55424 350 468 5.33E-38 T 26-04-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A4V04_RS12660 b6647d038160082390f5827a3652ca5a 1629 SMART SM00869 1358 1618 1.5E-21 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS12660 b6647d038160082390f5827a3652ca5a 1629 Gene3D G3DSA:2.40.128.130 1315 1629 5.7E-51 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS12660 b6647d038160082390f5827a3652ca5a 1629 SUPERFAMILY SSF103515 1334 1629 6.41E-36 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS12660 b6647d038160082390f5827a3652ca5a 1629 Pfam PF03797 Autotransporter beta-domain 1358 1611 1.0E-26 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS12660 b6647d038160082390f5827a3652ca5a 1629 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 1162 1629 2.6E-53 T 26-04-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 A4V04_RS04680 e7353d4991c9202501e28967544acedf 586 SMART SM00382 37 219 1.2E-10 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS04680 e7353d4991c9202501e28967544acedf 586 SMART SM00382 365 546 8.1E-11 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS04680 e7353d4991c9202501e28967544acedf 586 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS04680 e7353d4991c9202501e28967544acedf 586 Pfam PF00005 ABC transporter 357 500 4.2E-28 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS04680 e7353d4991c9202501e28967544acedf 586 Pfam PF00005 ABC transporter 30 172 2.5E-30 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS04680 e7353d4991c9202501e28967544acedf 586 SUPERFAMILY SSF52540 21 235 5.45E-58 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04680 e7353d4991c9202501e28967544acedf 586 Gene3D G3DSA:3.40.50.300 334 562 1.9E-66 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04680 e7353d4991c9202501e28967544acedf 586 Gene3D G3DSA:3.40.50.300 5 235 6.6E-67 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04680 e7353d4991c9202501e28967544acedf 586 SUPERFAMILY SSF52540 335 559 1.25E-57 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03095 3981260095f4741db71c77d5bea3e6be 206 Gene3D G3DSA:3.50.50.60 33 155 4.7E-36 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03095 3981260095f4741db71c77d5bea3e6be 206 SUPERFAMILY SSF51905 32 162 9.43E-27 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03095 3981260095f4741db71c77d5bea3e6be 206 Pfam PF00890 FAD binding domain 41 172 2.6E-31 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 SUPERFAMILY SSF55874 13 245 2.34E-60 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 Gene3D G3DSA:3.30.230.10 247 424 2.0E-65 T 26-04-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 SUPERFAMILY SSF56719 766 861 3.14E-12 T 26-04-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR01159 DNA gyrase subunit B signature 13 23 9.3E-68 T 26-04-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR01159 DNA gyrase subunit B signature 346 362 9.3E-68 T 26-04-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR01159 DNA gyrase subunit B signature 408 428 9.3E-68 T 26-04-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR01159 DNA gyrase subunit B signature 247 269 9.3E-68 T 26-04-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR01159 DNA gyrase subunit B signature 840 856 9.3E-68 T 26-04-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR01159 DNA gyrase subunit B signature 208 223 9.3E-68 T 26-04-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR01159 DNA gyrase subunit B signature 223 236 9.3E-68 T 26-04-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR01159 DNA gyrase subunit B signature 824 836 9.3E-68 T 26-04-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR01159 DNA gyrase subunit B signature 274 292 9.3E-68 T 26-04-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR01159 DNA gyrase subunit B signature 394 408 9.3E-68 T 26-04-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 ProSitePatterns PS00177 DNA topoisomerase II signature. 456 464 - T 26-04-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 SMART SM00387 39 203 6.4E-18 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 10 871 85.095 T 26-04-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 SMART SM00433 43 633 1.2E-223 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 Pfam PF00204 DNA gyrase B 248 424 2.0E-55 T 26-04-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 SUPERFAMILY SSF54211 248 424 1.9E-50 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR00418 DNA topoisomerase II family signature 520 536 1.6E-56 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR00418 DNA topoisomerase II family signature 43 58 1.6E-56 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR00418 DNA topoisomerase II family signature 558 570 1.6E-56 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR00418 DNA topoisomerase II family signature 538 555 1.6E-56 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR00418 DNA topoisomerase II family signature 300 313 1.6E-56 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR00418 DNA topoisomerase II family signature 454 468 1.6E-56 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR00418 DNA topoisomerase II family signature 78 91 1.6E-56 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 PRINTS PR00418 DNA topoisomerase II family signature 125 139 1.6E-56 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 Gene3D G3DSA:3.40.50.670 784 853 6.8E-85 T 26-04-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 Gene3D G3DSA:3.40.50.670 438 583 6.8E-85 T 26-04-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 803 860 2.0E-23 T 26-04-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 40 202 1.0E-19 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 Gene3D G3DSA:3.30.565.10 13 245 3.2E-86 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 SUPERFAMILY SSF56719 428 574 1.18E-61 T 26-04-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4V04_RS10470 a0afbf15d7765d2f27acd09b5e59bb1d 871 Pfam PF01751 Toprim domain 453 564 1.4E-16 T 26-04-2017 IPR006171 Toprim domain A4V04_RS03565 da10951c2bedd7e5a713f83b33f2827d 392 Pfam PF13406 Transglycosylase SLT domain 40 345 3.0E-86 T 26-04-2017 IPR031304 Transglycosylase SLT domain 2 A4V04_RS03565 da10951c2bedd7e5a713f83b33f2827d 392 Gene3D G3DSA:1.10.530.10 92 146 3.4E-46 T 26-04-2017 A4V04_RS03565 da10951c2bedd7e5a713f83b33f2827d 392 Gene3D G3DSA:1.10.530.10 228 349 3.4E-46 T 26-04-2017 A4V04_RS03565 da10951c2bedd7e5a713f83b33f2827d 392 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 44 348 9.8E-93 T 26-04-2017 IPR011757 Lytic transglycosylase MltB A4V04_RS03565 da10951c2bedd7e5a713f83b33f2827d 392 SUPERFAMILY SSF53955 31 349 1.2E-75 T 26-04-2017 IPR023346 Lysozyme-like domain A4V04_RS11920 5c337fd19b56c953117e130ad6d95d8b 417 Pfam PF13707 RloB-like protein 127 330 2.4E-20 T 26-04-2017 IPR025591 RloB-like protein A4V04_RS02125 707ffb6f0df1e6edf21b725891d0f288 475 PRINTS PR00149 Fumarate lyase superfamily signature 314 330 5.0E-21 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS02125 707ffb6f0df1e6edf21b725891d0f288 475 PRINTS PR00149 Fumarate lyase superfamily signature 268 295 5.0E-21 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS02125 707ffb6f0df1e6edf21b725891d0f288 475 PRINTS PR00149 Fumarate lyase superfamily signature 177 195 5.0E-21 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS02125 707ffb6f0df1e6edf21b725891d0f288 475 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 5.0E-21 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS02125 707ffb6f0df1e6edf21b725891d0f288 475 Gene3D G3DSA:1.20.200.10 137 400 3.7E-77 T 26-04-2017 A4V04_RS02125 707ffb6f0df1e6edf21b725891d0f288 475 SUPERFAMILY SSF48557 1 454 1.02E-112 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS02125 707ffb6f0df1e6edf21b725891d0f288 475 Pfam PF10415 Fumarase C C-terminus 406 457 1.1E-8 T 26-04-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS02125 707ffb6f0df1e6edf21b725891d0f288 475 Gene3D G3DSA:1.10.40.30 406 460 4.0E-9 T 26-04-2017 A4V04_RS02125 707ffb6f0df1e6edf21b725891d0f288 475 Gene3D G3DSA:1.10.275.10 1 136 1.3E-41 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS02125 707ffb6f0df1e6edf21b725891d0f288 475 Pfam PF00206 Lyase 10 339 1.3E-77 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS02125 707ffb6f0df1e6edf21b725891d0f288 475 ProSitePatterns PS00163 Fumarate lyases signature. 314 323 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS11695 87d7678e3ea01272f037e1a917ccaa92 396 SUPERFAMILY SSF53187 307 393 5.09E-70 T 26-04-2017 A4V04_RS11695 87d7678e3ea01272f037e1a917ccaa92 396 SUPERFAMILY SSF53187 18 204 5.09E-70 T 26-04-2017 A4V04_RS11695 87d7678e3ea01272f037e1a917ccaa92 396 SUPERFAMILY SSF55031 191 305 1.7E-28 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS11695 87d7678e3ea01272f037e1a917ccaa92 396 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 382 1.6E-99 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS11695 87d7678e3ea01272f037e1a917ccaa92 396 Gene3D G3DSA:3.40.630.10 14 185 3.0E-80 T 26-04-2017 A4V04_RS11695 87d7678e3ea01272f037e1a917ccaa92 396 Gene3D G3DSA:3.40.630.10 307 394 3.0E-80 T 26-04-2017 A4V04_RS11695 87d7678e3ea01272f037e1a917ccaa92 396 Pfam PF07687 Peptidase dimerisation domain 188 287 2.9E-7 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS11695 87d7678e3ea01272f037e1a917ccaa92 396 Pfam PF01546 Peptidase family M20/M25/M40 80 391 5.6E-32 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS11695 87d7678e3ea01272f037e1a917ccaa92 396 Gene3D G3DSA:3.30.70.360 188 306 9.1E-36 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS11695 87d7678e3ea01272f037e1a917ccaa92 396 PIRSF PIRSF005962 5 396 1.6E-111 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS04340 d1a9ab8be6433f2e8101af251408e53a 429 SUPERFAMILY SSF55681 116 422 5.24E-101 T 26-04-2017 A4V04_RS04340 d1a9ab8be6433f2e8101af251408e53a 429 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 228 404 1.1E-36 T 26-04-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS04340 d1a9ab8be6433f2e8101af251408e53a 429 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 426 39.893 T 26-04-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4V04_RS04340 d1a9ab8be6433f2e8101af251408e53a 429 SUPERFAMILY SSF46589 1 112 1.2E-29 T 26-04-2017 IPR010978 tRNA-binding arm GO:0000166 A4V04_RS04340 d1a9ab8be6433f2e8101af251408e53a 429 PRINTS PR00981 Seryl-tRNA synthetase signature 321 334 9.6E-33 T 26-04-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4V04_RS04340 d1a9ab8be6433f2e8101af251408e53a 429 PRINTS PR00981 Seryl-tRNA synthetase signature 281 294 9.6E-33 T 26-04-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4V04_RS04340 d1a9ab8be6433f2e8101af251408e53a 429 PRINTS PR00981 Seryl-tRNA synthetase signature 338 354 9.6E-33 T 26-04-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4V04_RS04340 d1a9ab8be6433f2e8101af251408e53a 429 PRINTS PR00981 Seryl-tRNA synthetase signature 269 281 9.6E-33 T 26-04-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4V04_RS04340 d1a9ab8be6433f2e8101af251408e53a 429 PRINTS PR00981 Seryl-tRNA synthetase signature 356 372 9.6E-33 T 26-04-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4V04_RS04340 d1a9ab8be6433f2e8101af251408e53a 429 Gene3D G3DSA:3.30.930.10 105 425 1.0E-141 T 26-04-2017 A4V04_RS04340 d1a9ab8be6433f2e8101af251408e53a 429 Gene3D G3DSA:1.10.287.40 1 104 3.5E-25 T 26-04-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4V04_RS04340 d1a9ab8be6433f2e8101af251408e53a 429 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 421 1.5E-168 T 26-04-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4V04_RS04340 d1a9ab8be6433f2e8101af251408e53a 429 PIRSF PIRSF001529 1 429 2.6E-179 T 26-04-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4V04_RS04340 d1a9ab8be6433f2e8101af251408e53a 429 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 8.0E-29 T 26-04-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4V04_RS06835 c3b15e1b9cbc571838b4d884d4f0c655 368 Gene3D G3DSA:1.10.645.10 5 73 3.3E-4 T 26-04-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS06835 c3b15e1b9cbc571838b4d884d4f0c655 368 SUPERFAMILY SSF56762 5 358 9.31E-20 T 26-04-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS06835 c3b15e1b9cbc571838b4d884d4f0c655 368 Gene3D G3DSA:1.10.645.10 235 358 1.1E-8 T 26-04-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS07175 3430562a061e4820b89307405f4f4ccb 235 SMART SM00862 154 230 7.5E-13 T 26-04-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4V04_RS07175 3430562a061e4820b89307405f4f4ccb 235 Pfam PF00072 Response regulator receiver domain 7 118 2.2E-31 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS07175 3430562a061e4820b89307405f4f4ccb 235 Gene3D G3DSA:1.10.10.10 136 231 2.5E-23 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07175 3430562a061e4820b89307405f4f4ccb 235 SUPERFAMILY SSF52172 7 181 3.98E-42 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS07175 3430562a061e4820b89307405f4f4ccb 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 229 5.5E-17 T 26-04-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4V04_RS07175 3430562a061e4820b89307405f4f4ccb 235 SMART SM00448 5 117 1.7E-45 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS07175 3430562a061e4820b89307405f4f4ccb 235 Gene3D G3DSA:3.40.50.2300 5 127 3.6E-42 T 26-04-2017 A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 Gene3D G3DSA:2.70.20.10 375 485 4.5E-36 T 26-04-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 Gene3D G3DSA:2.70.20.10 226 257 4.5E-36 T 26-04-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 TIGRFAM TIGR01056 topB: DNA topoisomerase III 2 612 1.0E-184 T 26-04-2017 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 SUPERFAMILY SSF56712 2 611 3.79E-162 T 26-04-2017 IPR023405 DNA topoisomerase, type IA, core domain A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 Pfam PF01751 Toprim domain 3 141 1.2E-14 T 26-04-2017 IPR006171 Toprim domain A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 Gene3D G3DSA:1.10.460.10 486 611 1.4E-47 T 26-04-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 Gene3D G3DSA:1.10.460.10 167 223 1.4E-47 T 26-04-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 SMART SM00493 1 134 4.2E-13 T 26-04-2017 IPR006171 Toprim domain A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 328 337 1.6E-21 T 26-04-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 525 539 1.6E-21 T 26-04-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 108 121 1.6E-21 T 26-04-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 409 425 1.6E-21 T 26-04-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 199 217 1.6E-21 T 26-04-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 Gene3D G3DSA:3.40.50.140 2 161 9.5E-38 T 26-04-2017 IPR006171 Toprim domain A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 Pfam PF01131 DNA topoisomerase 162 596 6.9E-109 T 26-04-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 SMART SM00437 285 562 3.1E-69 T 26-04-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A4V04_RS06210 1b9904242229bb7819bbf047666e58a3 616 SMART SM00436 134 229 6.9E-18 T 26-04-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 SUPERFAMILY SSF101904 547 866 1.57E-99 T 26-04-2017 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 Gene3D G3DSA:3.30.1360.40 247 344 8.7E-36 T 26-04-2017 IPR024946 Arginine repressor C-terminal-like domain A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 Gene3D G3DSA:2.120.10.90 545 855 6.2E-122 T 26-04-2017 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 Gene3D G3DSA:1.10.268.10 375 510 5.5E-32 T 26-04-2017 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 21 856 0.0 T 26-04-2017 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 SUPERFAMILY SSF56719 42 536 9.16E-167 T 26-04-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 SMART SM00434 22 513 5.1E-249 T 26-04-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 43 514 1.8E-143 T 26-04-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 760 806 2.4E-13 T 26-04-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 708 753 2.1E-12 T 26-04-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 553 597 1.1E-7 T 26-04-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 809 855 1.9E-11 T 26-04-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 602 636 5.8E-7 T 26-04-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 660 703 4.0E-10 T 26-04-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 16 857 23.116 T 26-04-2017 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4V04_RS01475 c19176f600184fb1ca0c40d688092217 909 Gene3D G3DSA:3.90.199.10 45 227 4.8E-79 T 26-04-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS11495 c493e3acf5e709d1fb61927a8fcaef38 194 Gene3D G3DSA:2.20.28.10 151 187 5.1E-12 T 26-04-2017 IPR004039 Rubredoxin-type fold A4V04_RS11495 c493e3acf5e709d1fb61927a8fcaef38 194 SUPERFAMILY SSF57802 152 190 1.99E-9 T 26-04-2017 A4V04_RS11495 c493e3acf5e709d1fb61927a8fcaef38 194 Pfam PF02915 Rubrerythrin 14 142 1.2E-15 T 26-04-2017 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A4V04_RS11495 c493e3acf5e709d1fb61927a8fcaef38 194 SUPERFAMILY SSF47240 8 149 4.43E-27 T 26-04-2017 IPR009078 Ferritin-like superfamily A4V04_RS11495 c493e3acf5e709d1fb61927a8fcaef38 194 Gene3D G3DSA:1.20.1260.10 5 148 4.0E-33 T 26-04-2017 IPR012347 Ferritin-related A4V04_RS07455 3d2581d2015af31bed5e97cc0ca946de 252 Gene3D G3DSA:3.40.50.300 6 243 8.7E-87 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07455 3d2581d2015af31bed5e97cc0ca946de 252 SMART SM00382 32 219 1.8E-12 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS07455 3d2581d2015af31bed5e97cc0ca946de 252 SUPERFAMILY SSF52540 7 241 3.69E-81 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07455 3d2581d2015af31bed5e97cc0ca946de 252 PIRSF PIRSF039085 4 247 3.1E-115 T 26-04-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A4V04_RS07455 3d2581d2015af31bed5e97cc0ca946de 252 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS07455 3d2581d2015af31bed5e97cc0ca946de 252 Pfam PF00005 ABC transporter 23 171 8.9E-36 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS09560 d2aa021ee35b99640d1bb0c7537a6186 309 SUPERFAMILY SSF52540 99 306 1.31E-45 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09560 d2aa021ee35b99640d1bb0c7537a6186 309 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 33 306 57.723 T 26-04-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A4V04_RS09560 d2aa021ee35b99640d1bb0c7537a6186 309 SMART SM00382 103 282 6.0E-5 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS09560 d2aa021ee35b99640d1bb0c7537a6186 309 Pfam PF00448 SRP54-type protein, GTPase domain 104 305 1.1E-71 T 26-04-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4V04_RS09560 d2aa021ee35b99640d1bb0c7537a6186 309 Gene3D G3DSA:1.20.120.140 3 76 2.9E-24 T 26-04-2017 A4V04_RS09560 d2aa021ee35b99640d1bb0c7537a6186 309 SMART SM00963 14 90 1.1E-16 T 26-04-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4V04_RS09560 d2aa021ee35b99640d1bb0c7537a6186 309 Gene3D G3DSA:3.40.50.300 77 113 3.2E-4 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09560 d2aa021ee35b99640d1bb0c7537a6186 309 Pfam PF02881 SRP54-type protein, helical bundle domain 28 84 7.1E-12 T 26-04-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4V04_RS09560 d2aa021ee35b99640d1bb0c7537a6186 309 SUPERFAMILY SSF47364 9 84 1.03E-17 T 26-04-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4V04_RS09560 d2aa021ee35b99640d1bb0c7537a6186 309 Gene3D G3DSA:3.40.50.300 114 306 3.3E-76 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09560 d2aa021ee35b99640d1bb0c7537a6186 309 SMART SM00962 104 306 4.2E-112 T 26-04-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4V04_RS09560 d2aa021ee35b99640d1bb0c7537a6186 309 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 34 305 5.3E-103 T 26-04-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A4V04_RS09560 d2aa021ee35b99640d1bb0c7537a6186 309 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 279 292 - T 26-04-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4V04_RS01780 e97f50cdfb967a2f3042a9aa52198c93 208 Pfam PF09673 Type-F conjugative transfer system pilin assembly protein 65 186 5.7E-24 T 26-04-2017 IPR019106 Type-F conjugative transfer system pilin assembly protein TrbC A4V04_RS09710 5ece27f97cd8d7c86778ffbef67ec398 479 SUPERFAMILY SSF48557 3 460 1.62E-121 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS09710 5ece27f97cd8d7c86778ffbef67ec398 479 Gene3D G3DSA:1.10.40.30 410 463 4.6E-13 T 26-04-2017 A4V04_RS09710 5ece27f97cd8d7c86778ffbef67ec398 479 Gene3D G3DSA:1.10.275.10 3 139 1.2E-48 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS09710 5ece27f97cd8d7c86778ffbef67ec398 479 ProSitePatterns PS00163 Fumarate lyases signature. 317 326 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS09710 5ece27f97cd8d7c86778ffbef67ec398 479 Pfam PF00206 Lyase 12 342 1.1E-85 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS09710 5ece27f97cd8d7c86778ffbef67ec398 479 Pfam PF10415 Fumarase C C-terminus 410 461 8.5E-13 T 26-04-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS09710 5ece27f97cd8d7c86778ffbef67ec398 479 Gene3D G3DSA:1.20.200.10 140 403 4.1E-75 T 26-04-2017 A4V04_RS09710 5ece27f97cd8d7c86778ffbef67ec398 479 PRINTS PR00149 Fumarate lyase superfamily signature 317 333 7.8E-29 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09710 5ece27f97cd8d7c86778ffbef67ec398 479 PRINTS PR00149 Fumarate lyase superfamily signature 180 198 7.8E-29 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09710 5ece27f97cd8d7c86778ffbef67ec398 479 PRINTS PR00149 Fumarate lyase superfamily signature 135 153 7.8E-29 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09710 5ece27f97cd8d7c86778ffbef67ec398 479 PRINTS PR00149 Fumarate lyase superfamily signature 271 298 7.8E-29 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 953 980 - T 26-04-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 Pfam PF00384 Molybdopterin oxidoreductase 110 679 1.1E-41 T 26-04-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 Gene3D G3DSA:2.20.25.90 42 92 1.9E-15 T 26-04-2017 A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 Gene3D G3DSA:2.40.40.20 848 1041 3.1E-48 T 26-04-2017 A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 Gene3D G3DSA:3.40.50.740 555 709 5.5E-61 T 26-04-2017 A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 Gene3D G3DSA:3.40.50.740 460 483 5.5E-61 T 26-04-2017 A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 Gene3D G3DSA:3.40.50.740 110 194 5.5E-61 T 26-04-2017 A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 48 91 1.8E-9 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 Gene3D G3DSA:3.40.228.10 390 459 6.8E-54 T 26-04-2017 A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 Gene3D G3DSA:3.40.228.10 196 308 6.8E-54 T 26-04-2017 A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 SMART SM00926 43 96 7.4E-12 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 SUPERFAMILY SSF53706 37 350 1.3E-252 T 26-04-2017 A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 SUPERFAMILY SSF53706 378 876 1.3E-252 T 26-04-2017 A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 SUPERFAMILY SSF50692 855 1041 1.31E-47 T 26-04-2017 IPR009010 Aspartate decarboxylase-like domain A4V04_RS04440 bd96219300ff284fdc238e0b779be7f2 1041 Pfam PF01568 Molydopterin dinucleotide binding domain 922 1034 6.8E-19 T 26-04-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4V04_RS05665 db036e4732bb2ed86243fadaf093b507 471 Pfam PF00120 Glutamine synthetase, catalytic domain 104 468 2.7E-135 T 26-04-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4V04_RS05665 db036e4732bb2ed86243fadaf093b507 471 Gene3D G3DSA:3.30.590.10 108 456 1.7E-136 T 26-04-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4V04_RS05665 db036e4732bb2ed86243fadaf093b507 471 Gene3D G3DSA:3.10.20.70 4 107 9.3E-41 T 26-04-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4V04_RS05665 db036e4732bb2ed86243fadaf093b507 471 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 388 400 - T 26-04-2017 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4V04_RS05665 db036e4732bb2ed86243fadaf093b507 471 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 26-04-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4V04_RS05665 db036e4732bb2ed86243fadaf093b507 471 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 469 1.1E-198 T 26-04-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4V04_RS05665 db036e4732bb2ed86243fadaf093b507 471 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 97 6.2E-31 T 26-04-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4V04_RS05665 db036e4732bb2ed86243fadaf093b507 471 SUPERFAMILY SSF54368 4 101 5.23E-37 T 26-04-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4V04_RS05665 db036e4732bb2ed86243fadaf093b507 471 SMART SM01230 104 381 5.9E-143 T 26-04-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4V04_RS05665 db036e4732bb2ed86243fadaf093b507 471 SUPERFAMILY SSF55931 104 469 1.37E-136 T 26-04-2017 A4V04_RS05665 db036e4732bb2ed86243fadaf093b507 471 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 26-04-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4V04_RS08625 6c0563c2f3748eab7813df65575b4405 334 Pfam PF01636 Phosphotransferase enzyme family 26 234 2.8E-26 T 26-04-2017 IPR002575 Aminoglycoside phosphotransferase A4V04_RS08625 6c0563c2f3748eab7813df65575b4405 334 SUPERFAMILY SSF56112 5 302 4.21E-48 T 26-04-2017 IPR011009 Protein kinase-like domain A4V04_RS08625 6c0563c2f3748eab7813df65575b4405 334 Gene3D G3DSA:3.30.200.20 4 93 4.5E-25 T 26-04-2017 A4V04_RS08625 6c0563c2f3748eab7813df65575b4405 334 Gene3D G3DSA:3.90.1200.10 95 325 6.3E-69 T 26-04-2017 A4V04_RS11635 70e8b4e36999ee37728612a5168e74ed 181 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 78 162 7.6E-32 T 26-04-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS11635 70e8b4e36999ee37728612a5168e74ed 181 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 3 73 1.0E-6 T 26-04-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS11635 70e8b4e36999ee37728612a5168e74ed 181 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 132 138 - T 26-04-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS11635 70e8b4e36999ee37728612a5168e74ed 181 Gene3D G3DSA:2.30.37.60 4 67 7.1E-4 T 26-04-2017 A4V04_RS11635 70e8b4e36999ee37728612a5168e74ed 181 SUPERFAMILY SSF46767 76 163 8.5E-29 T 26-04-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS11635 70e8b4e36999ee37728612a5168e74ed 181 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 77 161 2.4E-31 T 26-04-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS11635 70e8b4e36999ee37728612a5168e74ed 181 SUPERFAMILY SSF53155 3 81 4.32E-23 T 26-04-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS11635 70e8b4e36999ee37728612a5168e74ed 181 Gene3D G3DSA:1.10.10.10 76 166 7.1E-35 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 SUPERFAMILY SSF52540 122 182 1.66E-94 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 SUPERFAMILY SSF52540 15 71 1.66E-94 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 SUPERFAMILY SSF52540 403 658 1.66E-94 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 SUPERFAMILY SSF52540 221 365 1.66E-94 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 SUPERFAMILY SSF52540 696 722 1.66E-94 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 SUPERFAMILY SSF52980 853 1168 4.13E-49 T 26-04-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 Gene3D G3DSA:3.90.320.10 851 1170 6.6E-60 T 26-04-2017 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 Pfam PF13361 UvrD-like helicase C-terminal domain 337 716 2.4E-21 T 26-04-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 Gene3D G3DSA:3.40.50.300 130 189 1.7E-54 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 Gene3D G3DSA:3.40.50.300 15 67 1.7E-54 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 Gene3D G3DSA:3.40.50.300 231 334 1.7E-54 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 Gene3D G3DSA:1.10.486.10 483 620 1.9E-26 T 26-04-2017 A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 332 6.3E-60 T 26-04-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 Gene3D G3DSA:3.40.50.300 621 720 5.9E-42 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 Gene3D G3DSA:3.40.50.300 340 480 5.9E-42 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 Pfam PF12705 PD-(D/E)XK nuclease superfamily 901 1156 2.0E-7 T 26-04-2017 A4V04_RS13105 8cb1e4e9606fb8628f874c57060e5c3e 1190 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 5 1168 16.372 T 26-04-2017 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 A4V04_RS07100 c86293e62c2a75824ba15a6012fa02a1 389 SUPERFAMILY SSF48452 53 262 3.64E-20 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS07100 c86293e62c2a75824ba15a6012fa02a1 389 Gene3D G3DSA:1.25.40.10 38 312 3.8E-32 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS07100 c86293e62c2a75824ba15a6012fa02a1 389 SMART SM00028 215 248 26.0 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS07100 c86293e62c2a75824ba15a6012fa02a1 389 SMART SM00028 181 214 2.8 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS07100 c86293e62c2a75824ba15a6012fa02a1 389 SMART SM00028 69 102 21.0 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS07100 c86293e62c2a75824ba15a6012fa02a1 389 SMART SM00028 107 140 0.07 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS07100 c86293e62c2a75824ba15a6012fa02a1 389 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 6 385 29.884 T 26-04-2017 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 A4V04_RS07100 c86293e62c2a75824ba15a6012fa02a1 389 Pfam PF13432 Tetratricopeptide repeat 195 236 0.0028 T 26-04-2017 A4V04_RS07100 c86293e62c2a75824ba15a6012fa02a1 389 Pfam PF13424 Tetratricopeptide repeat 74 134 2.7E-8 T 26-04-2017 A4V04_RS01720 4459d2135a3292bed41cc20ce9677cc3 458 SUPERFAMILY SSF53098 142 299 2.88E-13 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS01720 4459d2135a3292bed41cc20ce9677cc3 458 Gene3D G3DSA:3.30.420.10 142 299 3.6E-16 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 351 489 1.9E-16 T 26-04-2017 IPR003959 ATPase, AAA-type, core GO:0005524 A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 SMART SM00382 347 493 5.4E-9 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 PIRSF PIRSF001174 1 774 0.0 T 26-04-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 355 374 4.1E-51 T 26-04-2017 A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 672 691 4.1E-51 T 26-04-2017 A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 594 610 4.1E-51 T 26-04-2017 A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 702 721 4.1E-51 T 26-04-2017 A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 725 743 4.1E-51 T 26-04-2017 A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 569 771 7.8E-90 T 26-04-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 SUPERFAMILY SSF52540 314 584 2.72E-48 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 Gene3D G3DSA:3.40.50.300 315 499 4.9E-31 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 TIGRFAM TIGR00763 lon: endopeptidase La 10 768 3.1E-281 T 26-04-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 SMART SM00464 8 204 4.8E-59 T 26-04-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 Gene3D G3DSA:1.10.8.60 500 583 4.7E-32 T 26-04-2017 A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 SUPERFAMILY SSF54211 594 767 2.81E-57 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 Gene3D G3DSA:3.30.230.10 587 767 8.4E-73 T 26-04-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 9 204 4.5E-38 T 26-04-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 SUPERFAMILY SSF88697 8 203 9.94E-41 T 26-04-2017 IPR015947 PUA-like domain A4V04_RS05055 725e8fb5fd825777b9fe71b190507e2c 800 Hamap MF_01973 Lon protease [lon]. 9 771 66.596 T 26-04-2017 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 A4V04_RS11860 966174202ddba2bae8a98831a02aff58 474 Gene3D G3DSA:3.40.50.300 254 460 2.2E-52 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11860 966174202ddba2bae8a98831a02aff58 474 ProSitePatterns PS00211 ABC transporters family signature. 389 403 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS11860 966174202ddba2bae8a98831a02aff58 474 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS11860 966174202ddba2bae8a98831a02aff58 474 Gene3D G3DSA:3.40.50.300 1 237 1.2E-57 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11860 966174202ddba2bae8a98831a02aff58 474 SUPERFAMILY SSF52540 261 461 3.65E-50 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11860 966174202ddba2bae8a98831a02aff58 474 SMART SM00382 285 464 3.8E-12 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS11860 966174202ddba2bae8a98831a02aff58 474 SMART SM00382 28 218 1.7E-6 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS11860 966174202ddba2bae8a98831a02aff58 474 SUPERFAMILY SSF52540 1 228 7.62E-53 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11860 966174202ddba2bae8a98831a02aff58 474 Pfam PF00005 ABC transporter 280 417 8.3E-27 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS11860 966174202ddba2bae8a98831a02aff58 474 Pfam PF00005 ABC transporter 19 169 2.1E-25 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS05255 85bbe943bc1b030920cc1ee757727af0 352 SMART SM00448 14 127 8.1E-22 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS05255 85bbe943bc1b030920cc1ee757727af0 352 Pfam PF00072 Response regulator receiver domain 16 119 6.8E-20 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS05255 85bbe943bc1b030920cc1ee757727af0 352 Gene3D G3DSA:3.40.50.2300 9 135 6.3E-29 T 26-04-2017 A4V04_RS05255 85bbe943bc1b030920cc1ee757727af0 352 SUPERFAMILY SSF52172 7 137 4.41E-29 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS06155 4e7d8838b0eab447934517f5b3db3ff4 222 Pfam PF01914 MarC family integral membrane protein 11 211 4.6E-37 T 26-04-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A4V04_RS06155 4e7d8838b0eab447934517f5b3db3ff4 222 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 10 209 9.2E-37 T 26-04-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 Gene3D G3DSA:3.30.70.240 583 667 1.0E-23 T 26-04-2017 IPR000640 Translation elongation factor EFG, V domain A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 Gene3D G3DSA:3.30.70.870 388 464 4.7E-21 T 26-04-2017 A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 SMART SM00838 584 672 1.4E-27 T 26-04-2017 IPR000640 Translation elongation factor EFG, V domain A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 Gene3D G3DSA:3.40.50.300 6 269 6.8E-48 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 SUPERFAMILY SSF54211 463 583 2.53E-41 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 Gene3D G3DSA:3.30.230.10 468 582 5.3E-47 T 26-04-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 178 4.5E-14 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 SUPERFAMILY SSF54980 388 466 7.91E-14 T 26-04-2017 IPR009022 Elongation factor G, III-V domain A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 Pfam PF00679 Elongation factor G C-terminus 585 671 3.9E-25 T 26-04-2017 IPR000640 Translation elongation factor EFG, V domain A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 SMART SM00889 464 582 3.5E-57 T 26-04-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 SUPERFAMILY SSF50447 248 378 5.3E-24 T 26-04-2017 IPR009000 Translation protein, beta-barrel domain A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 SUPERFAMILY SSF52540 5 265 2.23E-58 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 Pfam PF00009 Elongation factor Tu GTP binding domain 8 264 3.3E-35 T 26-04-2017 A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 Pfam PF03764 Elongation factor G, domain IV 463 582 6.7E-40 T 26-04-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 SUPERFAMILY SSF54980 585 674 9.11E-22 T 26-04-2017 IPR009022 Elongation factor G, III-V domain A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 Gene3D G3DSA:2.40.30.10 287 384 7.9E-19 T 26-04-2017 A4V04_RS08920 75a32110bb33fee4e2ee90332e749c5b 683 Pfam PF14492 Elongation Factor G, domain II 388 461 2.7E-18 T 26-04-2017 IPR009022 Elongation factor G, III-V domain A4V04_RS04455 009c02c9f3df38c009f8e8ecb667b325 385 SUPERFAMILY SSF103473 8 381 6.28E-40 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS04455 009c02c9f3df38c009f8e8ecb667b325 385 Pfam PF07690 Major Facilitator Superfamily 20 320 8.3E-21 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS04455 009c02c9f3df38c009f8e8ecb667b325 385 Gene3D G3DSA:1.20.1250.20 9 195 1.8E-14 T 26-04-2017 A4V04_RS04455 009c02c9f3df38c009f8e8ecb667b325 385 Gene3D G3DSA:1.20.1250.20 204 384 3.9E-14 T 26-04-2017 A4V04_RS02515 8ee09f84c1c84ecd80e0e942878ae6e4 373 Pfam PF13395 HNH endonuclease 259 296 5.0E-5 T 26-04-2017 IPR003615 HNH nuclease A4V04_RS05915 94acd2ecd431eb15669a9daf841e222f 269 Gene3D G3DSA:3.90.230.10 6 259 9.9E-88 T 26-04-2017 IPR000994 Peptidase M24, structural domain A4V04_RS05915 94acd2ecd431eb15669a9daf841e222f 269 SUPERFAMILY SSF55920 6 259 3.93E-84 T 26-04-2017 IPR000994 Peptidase M24, structural domain A4V04_RS05915 94acd2ecd431eb15669a9daf841e222f 269 Pfam PF00557 Metallopeptidase family M24 15 249 8.9E-47 T 26-04-2017 IPR000994 Peptidase M24, structural domain A4V04_RS05915 94acd2ecd431eb15669a9daf841e222f 269 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 6 256 7.8E-90 T 26-04-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 A4V04_RS05915 94acd2ecd431eb15669a9daf841e222f 269 PRINTS PR00599 Methionine aminopeptidase-1 signature 77 90 5.7E-21 T 26-04-2017 IPR001714 Peptidase M24, methionine aminopeptidase A4V04_RS05915 94acd2ecd431eb15669a9daf841e222f 269 PRINTS PR00599 Methionine aminopeptidase-1 signature 99 115 5.7E-21 T 26-04-2017 IPR001714 Peptidase M24, methionine aminopeptidase A4V04_RS05915 94acd2ecd431eb15669a9daf841e222f 269 PRINTS PR00599 Methionine aminopeptidase-1 signature 169 181 5.7E-21 T 26-04-2017 IPR001714 Peptidase M24, methionine aminopeptidase A4V04_RS05915 94acd2ecd431eb15669a9daf841e222f 269 PRINTS PR00599 Methionine aminopeptidase-1 signature 200 212 5.7E-21 T 26-04-2017 IPR001714 Peptidase M24, methionine aminopeptidase A4V04_RS05915 94acd2ecd431eb15669a9daf841e222f 269 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 175 193 - T 26-04-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 A4V04_RS05915 94acd2ecd431eb15669a9daf841e222f 269 Hamap MF_01974 Methionine aminopeptidase [map]. 6 258 38.006 T 26-04-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 A4V04_RS11480 5ff50b540d6bab52c495a7f9aeb81db1 350 Pfam PF00710 Asparaginase, N-terminal 25 218 1.9E-59 T 26-04-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A4V04_RS11480 5ff50b540d6bab52c495a7f9aeb81db1 350 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 5 350 2.2E-142 T 26-04-2017 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 A4V04_RS11480 5ff50b540d6bab52c495a7f9aeb81db1 350 Gene3D G3DSA:3.40.50.1170 22 234 2.8E-71 T 26-04-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A4V04_RS11480 5ff50b540d6bab52c495a7f9aeb81db1 350 SMART SM00870 25 344 1.5E-141 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS11480 5ff50b540d6bab52c495a7f9aeb81db1 350 Gene3D G3DSA:3.40.50.40 238 348 2.5E-38 T 26-04-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 A4V04_RS11480 5ff50b540d6bab52c495a7f9aeb81db1 350 SUPERFAMILY SSF53774 23 349 2.36E-103 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS11480 5ff50b540d6bab52c495a7f9aeb81db1 350 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 28 36 - T 26-04-2017 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A4V04_RS11480 5ff50b540d6bab52c495a7f9aeb81db1 350 PIRSF PIRSF500176 22 350 2.7E-79 T 26-04-2017 A4V04_RS11480 5ff50b540d6bab52c495a7f9aeb81db1 350 PIRSF PIRSF001220 20 350 6.1E-92 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS11480 5ff50b540d6bab52c495a7f9aeb81db1 350 PRINTS PR00139 Asparaginase/glutaminase family signature 285 303 6.8E-22 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS11480 5ff50b540d6bab52c495a7f9aeb81db1 350 PRINTS PR00139 Asparaginase/glutaminase family signature 26 37 6.8E-22 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS11480 5ff50b540d6bab52c495a7f9aeb81db1 350 PRINTS PR00139 Asparaginase/glutaminase family signature 106 124 6.8E-22 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS11480 5ff50b540d6bab52c495a7f9aeb81db1 350 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 107 117 - T 26-04-2017 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A4V04_RS01305 bd9d0d645a9622f6c495a22ecc4bd806 312 SUPERFAMILY SSF103481 181 272 4.45E-7 T 26-04-2017 A4V04_RS01305 bd9d0d645a9622f6c495a22ecc4bd806 312 SUPERFAMILY SSF103481 31 132 3.53E-5 T 26-04-2017 A4V04_RS12955 0328865323980c1b782bee53fc5f0956 233 SMART SM00448 3 116 1.5E-43 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS12955 0328865323980c1b782bee53fc5f0956 233 SUPERFAMILY SSF52172 3 127 1.71E-41 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS12955 0328865323980c1b782bee53fc5f0956 233 SMART SM00862 151 226 9.5E-24 T 26-04-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4V04_RS12955 0328865323980c1b782bee53fc5f0956 233 Pfam PF00072 Response regulator receiver domain 5 117 1.0E-28 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS12955 0328865323980c1b782bee53fc5f0956 233 Gene3D G3DSA:1.10.10.10 129 228 1.3E-32 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS12955 0328865323980c1b782bee53fc5f0956 233 SUPERFAMILY SSF46894 127 225 1.55E-30 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS12955 0328865323980c1b782bee53fc5f0956 233 Gene3D G3DSA:3.40.50.2300 3 128 4.2E-41 T 26-04-2017 A4V04_RS12955 0328865323980c1b782bee53fc5f0956 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 225 2.6E-25 T 26-04-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4V04_RS07895 1718b3e648500db0bc312eddf3bccda0 291 Gene3D G3DSA:3.40.50.300 3 229 8.2E-62 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07895 1718b3e648500db0bc312eddf3bccda0 291 Pfam PF00005 ABC transporter 20 154 3.1E-31 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS07895 1718b3e648500db0bc312eddf3bccda0 291 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS07895 1718b3e648500db0bc312eddf3bccda0 291 SUPERFAMILY SSF52540 3 219 7.35E-56 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07895 1718b3e648500db0bc312eddf3bccda0 291 SMART SM00382 28 203 3.4E-12 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS03080 1529617f1514eb0af6ae67d147044824 907 Gene3D G3DSA:3.30.1360.40 307 423 1.6E-19 T 26-04-2017 IPR024946 Arginine repressor C-terminal-like domain A4V04_RS03080 1529617f1514eb0af6ae67d147044824 907 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 74 831 30.618 T 26-04-2017 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4V04_RS03080 1529617f1514eb0af6ae67d147044824 907 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 102 554 9.7E-123 T 26-04-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03080 1529617f1514eb0af6ae67d147044824 907 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 80 769 9.0E-217 T 26-04-2017 A4V04_RS03080 1529617f1514eb0af6ae67d147044824 907 Gene3D G3DSA:3.90.199.10 425 490 1.8E-102 T 26-04-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03080 1529617f1514eb0af6ae67d147044824 907 Gene3D G3DSA:3.90.199.10 101 306 1.8E-102 T 26-04-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03080 1529617f1514eb0af6ae67d147044824 907 Gene3D G3DSA:2.120.10.90 587 791 1.5E-25 T 26-04-2017 A4V04_RS03080 1529617f1514eb0af6ae67d147044824 907 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 686 710 0.76 T 26-04-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4V04_RS03080 1529617f1514eb0af6ae67d147044824 907 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 633 667 0.079 T 26-04-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4V04_RS03080 1529617f1514eb0af6ae67d147044824 907 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 738 779 2.7E-5 T 26-04-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4V04_RS03080 1529617f1514eb0af6ae67d147044824 907 SUPERFAMILY SSF101904 590 825 1.96E-41 T 26-04-2017 A4V04_RS03080 1529617f1514eb0af6ae67d147044824 907 SUPERFAMILY SSF56719 101 575 6.93E-142 T 26-04-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4V04_RS03080 1529617f1514eb0af6ae67d147044824 907 SMART SM00434 81 553 1.2E-197 T 26-04-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS00335 c56cb9da4883106717d18a7d1d6fb64f 397 Gene3D G3DSA:3.90.105.10 127 158 1.1E-20 T 26-04-2017 A4V04_RS00335 c56cb9da4883106717d18a7d1d6fb64f 397 SUPERFAMILY SSF63882 1 171 4.45E-47 T 26-04-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS00335 c56cb9da4883106717d18a7d1d6fb64f 397 Gene3D G3DSA:2.40.340.10 337 393 7.3E-10 T 26-04-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS00335 c56cb9da4883106717d18a7d1d6fb64f 397 Gene3D G3DSA:2.170.190.11 45 126 2.5E-27 T 26-04-2017 A4V04_RS00335 c56cb9da4883106717d18a7d1d6fb64f 397 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 173 309 1.5E-25 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS00335 c56cb9da4883106717d18a7d1d6fb64f 397 Pfam PF00994 Probable molybdopterin binding domain 180 311 1.6E-23 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS00335 c56cb9da4883106717d18a7d1d6fb64f 397 Gene3D G3DSA:3.40.980.10 159 326 1.1E-60 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS00335 c56cb9da4883106717d18a7d1d6fb64f 397 SUPERFAMILY SSF63867 333 394 1.26E-12 T 26-04-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS00335 c56cb9da4883106717d18a7d1d6fb64f 397 Pfam PF03454 MoeA C-terminal region (domain IV) 327 392 1.7E-11 T 26-04-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS00335 c56cb9da4883106717d18a7d1d6fb64f 397 SMART SM00852 176 313 1.1E-39 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS00335 c56cb9da4883106717d18a7d1d6fb64f 397 SUPERFAMILY SSF53218 174 319 1.57E-41 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS00335 c56cb9da4883106717d18a7d1d6fb64f 397 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 163 5.1E-35 T 26-04-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS00305 8e3ef7b6123f760a20333f9bbb659924 292 Pfam PF01145 SPFH domain / Band 7 family 24 201 5.1E-29 T 26-04-2017 IPR001107 Band 7 domain A4V04_RS00305 8e3ef7b6123f760a20333f9bbb659924 292 SUPERFAMILY SSF117892 55 191 3.14E-24 T 26-04-2017 IPR001107 Band 7 domain A4V04_RS00305 8e3ef7b6123f760a20333f9bbb659924 292 TIGRFAM TIGR01932 hflC: HflC protein 139 285 5.8E-47 T 26-04-2017 IPR010200 HflC GO:0016021|GO:0052547 A4V04_RS00305 8e3ef7b6123f760a20333f9bbb659924 292 SMART SM00244 20 185 1.3E-23 T 26-04-2017 IPR001107 Band 7 domain A4V04_RS00305 8e3ef7b6123f760a20333f9bbb659924 292 PIRSF PIRSF005651 1 292 5.7E-88 T 26-04-2017 IPR010200 HflC GO:0016021|GO:0052547 A4V04_RS05515 c52f4329a0d8cb940ebd9d9eb8f07cc8 322 Pfam PF07282 Putative transposase DNA-binding domain 184 250 1.1E-13 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS05515 c52f4329a0d8cb940ebd9d9eb8f07cc8 322 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 153 208 4.1E-7 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS04290 14988f6f77913cb9ecc5af0920ed498d 509 SUPERFAMILY SSF53613 221 464 1.31E-56 T 26-04-2017 IPR029056 Ribokinase-like A4V04_RS04290 14988f6f77913cb9ecc5af0920ed498d 509 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 1 208 21.674 T 26-04-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4V04_RS04290 14988f6f77913cb9ecc5af0920ed498d 509 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 16 207 4.5E-40 T 26-04-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4V04_RS04290 14988f6f77913cb9ecc5af0920ed498d 509 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 218 486 19.179 T 26-04-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A4V04_RS04290 14988f6f77913cb9ecc5af0920ed498d 509 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 224 459 1.8E-54 T 26-04-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A4V04_RS04290 14988f6f77913cb9ecc5af0920ed498d 509 SUPERFAMILY SSF64153 9 239 1.29E-51 T 26-04-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4V04_RS04290 14988f6f77913cb9ecc5af0920ed498d 509 Gene3D G3DSA:3.40.50.10260 6 224 7.7E-55 T 26-04-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4V04_RS04290 14988f6f77913cb9ecc5af0920ed498d 509 Pfam PF01256 Carbohydrate kinase 242 461 3.8E-53 T 26-04-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A4V04_RS04290 14988f6f77913cb9ecc5af0920ed498d 509 Gene3D G3DSA:3.40.1190.20 225 475 6.9E-70 T 26-04-2017 IPR029056 Ribokinase-like A4V04_RS04290 14988f6f77913cb9ecc5af0920ed498d 509 PIRSF PIRSF017184 7 486 4.0E-107 T 26-04-2017 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 A4V04_RS04290 14988f6f77913cb9ecc5af0920ed498d 509 Pfam PF03853 YjeF-related protein N-terminus 26 187 5.4E-40 T 26-04-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4V04_RS03960 9a80d550f4418fbe976cba95f7872639 287 Pfam PF04321 RmlD substrate binding domain 3 281 3.4E-78 T 26-04-2017 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 A4V04_RS03960 9a80d550f4418fbe976cba95f7872639 287 SUPERFAMILY SSF51735 1 280 3.74E-69 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03960 9a80d550f4418fbe976cba95f7872639 287 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 3 280 1.1E-74 T 26-04-2017 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581 A4V04_RS03960 9a80d550f4418fbe976cba95f7872639 287 Gene3D G3DSA:3.40.50.720 1 229 1.5E-50 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS00870 96b558fed290b4922cd26992f80c8ec8 70 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 26-04-2017 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS00870 96b558fed290b4922cd26992f80c8ec8 70 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.1E-15 T 26-04-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00870 96b558fed290b4922cd26992f80c8ec8 70 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.1E-15 T 26-04-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00870 96b558fed290b4922cd26992f80c8ec8 70 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.1E-15 T 26-04-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00870 96b558fed290b4922cd26992f80c8ec8 70 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.1E-15 T 26-04-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00870 96b558fed290b4922cd26992f80c8ec8 70 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 5.2E-24 T 26-04-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00870 96b558fed290b4922cd26992f80c8ec8 70 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.115 T 26-04-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00870 96b558fed290b4922cd26992f80c8ec8 70 Pfam PF01165 Ribosomal protein S21 3 57 1.8E-21 T 26-04-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00870 96b558fed290b4922cd26992f80c8ec8 70 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 39 1.0E-5 T 26-04-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS03355 7211ee9ba346e66b9344e9d84982d1e3 622 Gene3D G3DSA:1.10.150.20 568 621 1.8E-21 T 26-04-2017 A4V04_RS03355 7211ee9ba346e66b9344e9d84982d1e3 622 SUPERFAMILY SSF47781 534 621 5.72E-21 T 26-04-2017 IPR010994 RuvA domain 2-like A4V04_RS03355 7211ee9ba346e66b9344e9d84982d1e3 622 SUPERFAMILY SSF46600 201 250 2.35E-11 T 26-04-2017 IPR001943 UVR domain GO:0005515 A4V04_RS03355 7211ee9ba346e66b9344e9d84982d1e3 622 Gene3D G3DSA:4.10.860.10 192 250 3.0E-16 T 26-04-2017 IPR001943 UVR domain GO:0005515 A4V04_RS03355 7211ee9ba346e66b9344e9d84982d1e3 622 Pfam PF01541 GIY-YIG catalytic domain 30 100 7.6E-8 T 26-04-2017 IPR000305 GIY-YIG nuclease superfamily A4V04_RS03355 7211ee9ba346e66b9344e9d84982d1e3 622 SMART SM00465 28 108 2.9E-16 T 26-04-2017 IPR000305 GIY-YIG nuclease superfamily A4V04_RS03355 7211ee9ba346e66b9344e9d84982d1e3 622 Hamap MF_00203 UvrABC system protein C [uvrC]. 15 619 26.132 T 26-04-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 A4V04_RS03355 7211ee9ba346e66b9344e9d84982d1e3 622 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 20 601 7.4E-167 T 26-04-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 A4V04_RS03355 7211ee9ba346e66b9344e9d84982d1e3 622 Pfam PF02151 UvrB/uvrC motif 215 247 8.0E-9 T 26-04-2017 IPR001943 UVR domain GO:0005515 A4V04_RS03355 7211ee9ba346e66b9344e9d84982d1e3 622 Pfam PF14520 Helix-hairpin-helix domain 570 620 9.5E-10 T 26-04-2017 A4V04_RS03355 7211ee9ba346e66b9344e9d84982d1e3 622 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 408 554 1.2E-45 T 26-04-2017 IPR001162 UvrC family homology region A4V04_RS03355 7211ee9ba346e66b9344e9d84982d1e3 622 SUPERFAMILY SSF82771 28 110 1.83E-19 T 26-04-2017 IPR000305 GIY-YIG nuclease superfamily A4V04_RS03355 7211ee9ba346e66b9344e9d84982d1e3 622 Gene3D G3DSA:3.40.1440.10 29 106 3.3E-5 T 26-04-2017 IPR027299 GIY-YIG domain A4V04_RS04500 5d098b4ebefd35cd86fd5df3ed5b41ae 271 Pfam PF02634 FdhD/NarQ family 31 267 4.4E-67 T 26-04-2017 IPR003786 Protein FdhD GO:0016783 A4V04_RS04500 5d098b4ebefd35cd86fd5df3ed5b41ae 271 SUPERFAMILY SSF53927 23 267 2.17E-70 T 26-04-2017 IPR016193 Cytidine deaminase-like GO:0003824 A4V04_RS04500 5d098b4ebefd35cd86fd5df3ed5b41ae 271 Gene3D G3DSA:3.40.140.10 134 267 2.4E-42 T 26-04-2017 A4V04_RS04500 5d098b4ebefd35cd86fd5df3ed5b41ae 271 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 27 267 3.2E-75 T 26-04-2017 IPR003786 Protein FdhD GO:0016783 A4V04_RS04500 5d098b4ebefd35cd86fd5df3ed5b41ae 271 Gene3D G3DSA:3.10.20.10 33 120 1.6E-27 T 26-04-2017 A4V04_RS04500 5d098b4ebefd35cd86fd5df3ed5b41ae 271 PIRSF PIRSF015626 9 270 1.4E-74 T 26-04-2017 IPR003786 Protein FdhD GO:0016783 A4V04_RS04500 5d098b4ebefd35cd86fd5df3ed5b41ae 271 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 9 268 31.418 T 26-04-2017 IPR003786 Protein FdhD GO:0016783 A4V04_RS00095 e278eb6ada96d2b7ddf70d5601947e2e 699 SUPERFAMILY SSF109604 18 184 1.07E-35 T 26-04-2017 A4V04_RS00095 e278eb6ada96d2b7ddf70d5601947e2e 699 Pfam PF13328 HD domain 17 170 5.5E-38 T 26-04-2017 IPR003607 HD/PDEase domain A4V04_RS00095 e278eb6ada96d2b7ddf70d5601947e2e 699 SUPERFAMILY SSF81271 375 437 1.35E-17 T 26-04-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A4V04_RS00095 e278eb6ada96d2b7ddf70d5601947e2e 699 SMART SM00954 229 339 2.7E-58 T 26-04-2017 IPR007685 RelA/SpoT GO:0015969 A4V04_RS00095 e278eb6ada96d2b7ddf70d5601947e2e 699 SUPERFAMILY SSF55021 623 698 5.95E-11 T 26-04-2017 A4V04_RS00095 e278eb6ada96d2b7ddf70d5601947e2e 699 Gene3D G3DSA:3.30.70.260 625 696 1.0E-13 T 26-04-2017 A4V04_RS00095 e278eb6ada96d2b7ddf70d5601947e2e 699 Pfam PF13291 ACT domain 623 698 3.8E-15 T 26-04-2017 IPR002912 ACT domain GO:0008152|GO:0016597 A4V04_RS00095 e278eb6ada96d2b7ddf70d5601947e2e 699 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 21 697 2.0E-168 T 26-04-2017 IPR004811 RelA/SpoT family GO:0015969 A4V04_RS00095 e278eb6ada96d2b7ddf70d5601947e2e 699 Pfam PF02824 TGS domain 378 437 2.6E-21 T 26-04-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 A4V04_RS00095 e278eb6ada96d2b7ddf70d5601947e2e 699 SUPERFAMILY SSF81301 186 360 9.65E-57 T 26-04-2017 A4V04_RS00095 e278eb6ada96d2b7ddf70d5601947e2e 699 Pfam PF04607 Region found in RelA / SpoT proteins 229 339 1.3E-37 T 26-04-2017 IPR007685 RelA/SpoT GO:0015969 A4V04_RS00095 e278eb6ada96d2b7ddf70d5601947e2e 699 Gene3D G3DSA:3.30.460.10 171 319 5.7E-48 T 26-04-2017 A4V04_RS00095 e278eb6ada96d2b7ddf70d5601947e2e 699 Gene3D G3DSA:3.10.20.30 378 439 1.4E-22 T 26-04-2017 IPR012675 Beta-grasp domain A4V04_RS02705 d596b62a5ec530c66f45d566cdd630ba 382 Pfam PF01479 S4 domain 76 120 2.7E-8 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS02705 d596b62a5ec530c66f45d566cdd630ba 382 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 144 304 8.5E-56 T 26-04-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A4V04_RS02705 d596b62a5ec530c66f45d566cdd630ba 382 SUPERFAMILY SSF55174 77 168 8.54E-16 T 26-04-2017 A4V04_RS02705 d596b62a5ec530c66f45d566cdd630ba 382 Gene3D G3DSA:3.10.290.10 75 130 7.6E-16 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS02705 d596b62a5ec530c66f45d566cdd630ba 382 Pfam PF00849 RNA pseudouridylate synthase 140 273 4.0E-19 T 26-04-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS02705 d596b62a5ec530c66f45d566cdd630ba 382 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 178 192 - T 26-04-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A4V04_RS02705 d596b62a5ec530c66f45d566cdd630ba 382 SMART SM00363 75 135 1.2E-7 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS02705 d596b62a5ec530c66f45d566cdd630ba 382 SUPERFAMILY SSF55120 140 305 1.32E-42 T 26-04-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS07720 8aea167b453bbe9351b8082805eb1a79 144 PIRSF PIRSF001399 1 144 3.4E-62 T 26-04-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4V04_RS07720 8aea167b453bbe9351b8082805eb1a79 144 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 18 142 3.0E-40 T 26-04-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4V04_RS07720 8aea167b453bbe9351b8082805eb1a79 144 SUPERFAMILY SSF52304 3 142 4.19E-62 T 26-04-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4V04_RS07720 8aea167b453bbe9351b8082805eb1a79 144 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 144 69.285 T 26-04-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4V04_RS07720 8aea167b453bbe9351b8082805eb1a79 144 Pfam PF01220 Dehydroquinase class II 3 140 2.7E-60 T 26-04-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4V04_RS07720 8aea167b453bbe9351b8082805eb1a79 144 Gene3D G3DSA:3.40.50.9100 3 142 5.1E-66 T 26-04-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4V04_RS07720 8aea167b453bbe9351b8082805eb1a79 144 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 142 2.6E-61 T 26-04-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4V04_RS07720 8aea167b453bbe9351b8082805eb1a79 144 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 26-04-2017 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4V04_RS07035 fd3daa0cddcc0ceeed4055faad01eee8 106 SUPERFAMILY SSF52833 2 105 2.21E-34 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS07035 fd3daa0cddcc0ceeed4055faad01eee8 106 ProSitePatterns PS00194 Thioredoxin family active site. 23 41 - T 26-04-2017 IPR017937 Thioredoxin, conserved site GO:0045454 A4V04_RS07035 fd3daa0cddcc0ceeed4055faad01eee8 106 Pfam PF00085 Thioredoxin 5 104 8.0E-30 T 26-04-2017 IPR013766 Thioredoxin domain GO:0045454 A4V04_RS07035 fd3daa0cddcc0ceeed4055faad01eee8 106 Gene3D G3DSA:3.40.30.10 4 104 3.2E-34 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS07035 fd3daa0cddcc0ceeed4055faad01eee8 106 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 105 2.7E-32 T 26-04-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4V04_RS07035 fd3daa0cddcc0ceeed4055faad01eee8 106 PIRSF PIRSF000077 1 106 1.5E-35 T 26-04-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4V04_RS07035 fd3daa0cddcc0ceeed4055faad01eee8 106 PRINTS PR00421 Thioredoxin family signature 30 39 1.2E-8 T 26-04-2017 A4V04_RS07035 fd3daa0cddcc0ceeed4055faad01eee8 106 PRINTS PR00421 Thioredoxin family signature 70 81 1.2E-8 T 26-04-2017 A4V04_RS07035 fd3daa0cddcc0ceeed4055faad01eee8 106 PRINTS PR00421 Thioredoxin family signature 22 30 1.2E-8 T 26-04-2017 A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 SUPERFAMILY SSF47384 561 637 2.35E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 SMART SM00388 568 639 3.2E-8 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 Gene3D G3DSA:3.30.565.10 626 791 2.3E-38 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 SMART SM00387 682 792 2.6E-29 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 SMART SM00091 319 390 0.0016 T 26-04-2017 IPR000014 PAS domain A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 Gene3D G3DSA:3.30.450.20 330 433 1.7E-12 T 26-04-2017 A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 PRINTS PR00344 Bacterial sensor protein C-terminal signature 776 789 1.6E-11 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 PRINTS PR00344 Bacterial sensor protein C-terminal signature 741 751 1.6E-11 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 PRINTS PR00344 Bacterial sensor protein C-terminal signature 723 737 1.6E-11 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 PRINTS PR00344 Bacterial sensor protein C-terminal signature 752 770 1.6E-11 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 SUPERFAMILY SSF55785 329 433 1.57E-13 T 26-04-2017 IPR000014 PAS domain A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 Pfam PF13426 PAS domain 330 433 1.7E-10 T 26-04-2017 IPR000014 PAS domain A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 Pfam PF00512 His Kinase A (phospho-acceptor) domain 569 638 1.5E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 683 789 3.3E-20 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 SUPERFAMILY SSF55874 628 790 5.11E-37 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 319 433 1.9E-9 T 26-04-2017 IPR000014 PAS domain A4V04_RS05625 ee9caee85d2b5ae7542504849c7e958c 794 Gene3D G3DSA:1.10.287.130 568 625 2.9E-7 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10505 0a9bd63f185663d7e30a70c7192537f9 394 Pfam PF07690 Major Facilitator Superfamily 12 349 1.5E-39 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS10505 0a9bd63f185663d7e30a70c7192537f9 394 SUPERFAMILY SSF103473 5 376 6.15E-54 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS10505 0a9bd63f185663d7e30a70c7192537f9 394 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 3 369 2.7E-76 T 26-04-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 A4V04_RS10505 0a9bd63f185663d7e30a70c7192537f9 394 Gene3D G3DSA:1.20.1250.20 7 187 1.9E-29 T 26-04-2017 A4V04_RS10505 0a9bd63f185663d7e30a70c7192537f9 394 Gene3D G3DSA:1.20.1250.20 203 378 3.6E-8 T 26-04-2017 A4V04_RS10505 0a9bd63f185663d7e30a70c7192537f9 394 ProSitePatterns PS00216 Sugar transport proteins signature 1. 60 76 - T 26-04-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 Gene3D G3DSA:2.40.37.10 277 428 7.6E-43 T 26-04-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 171 180 1.1E-25 T 26-04-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 82 99 1.1E-25 T 26-04-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 393 415 1.1E-25 T 26-04-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 309 327 1.1E-25 T 26-04-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 14 425 1.6E-154 T 26-04-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 45 291 1.8E-68 T 26-04-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 64 82 - T 26-04-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 Gene3D G3DSA:3.20.20.10 43 276 7.8E-79 T 26-04-2017 IPR029066 PLP-binding barrel A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 84 96 2.0E-23 T 26-04-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 64 82 2.0E-23 T 26-04-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 383 396 2.0E-23 T 26-04-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 197 210 2.0E-23 T 26-04-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 281 300 2.0E-23 T 26-04-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 SUPERFAMILY SSF51419 33 293 1.09E-77 T 26-04-2017 IPR029066 PLP-binding barrel A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 22 426 40.331 T 26-04-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 SUPERFAMILY SSF50621 268 427 1.61E-48 T 26-04-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4V04_RS12980 b34045cf979a4cf6af337790efdeb8a6 430 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 296 402 9.8E-17 T 26-04-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A4V04_RS02655 23babfd34047dc1a4ee6bfe86d8c200c 365 SUPERFAMILY SSF53383 24 359 7.58E-62 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS02655 23babfd34047dc1a4ee6bfe86d8c200c 365 Gene3D G3DSA:3.40.640.10 39 264 5.4E-53 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS02655 23babfd34047dc1a4ee6bfe86d8c200c 365 Gene3D G3DSA:3.90.1150.10 265 359 4.3E-13 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS02655 23babfd34047dc1a4ee6bfe86d8c200c 365 Pfam PF00155 Aminotransferase class I and II 24 356 1.9E-45 T 26-04-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 Pfam PF00390 Malic enzyme, N-terminal domain 72 249 7.6E-72 T 26-04-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 Gene3D G3DSA:3.40.50.720 259 538 3.3E-107 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 PIRSF PIRSF000106 1 540 2.1E-216 T 26-04-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 Gene3D G3DSA:3.40.50.10380 6 258 6.4E-110 T 26-04-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 Pfam PF03949 Malic enzyme, NAD binding domain 261 511 8.3E-92 T 26-04-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 SMART SM01274 71 251 9.2E-96 T 26-04-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 PRINTS PR00072 Malic enzyme signature 173 195 2.5E-73 T 26-04-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 PRINTS PR00072 Malic enzyme signature 232 250 2.5E-73 T 26-04-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 PRINTS PR00072 Malic enzyme signature 257 273 2.5E-73 T 26-04-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 PRINTS PR00072 Malic enzyme signature 389 405 2.5E-73 T 26-04-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 PRINTS PR00072 Malic enzyme signature 77 101 2.5E-73 T 26-04-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 PRINTS PR00072 Malic enzyme signature 137 166 2.5E-73 T 26-04-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 PRINTS PR00072 Malic enzyme signature 288 304 2.5E-73 T 26-04-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 SUPERFAMILY SSF51735 261 538 1.79E-92 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 ProSitePatterns PS00331 Malic enzymes signature. 257 273 - T 26-04-2017 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 SUPERFAMILY SSF53223 4 260 2.66E-98 T 26-04-2017 A4V04_RS08585 5b6e48b917a1daf608d63db8a235d9d0 540 SMART SM00919 261 512 1.1E-105 T 26-04-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 A4V04_RS08535 8a228f0715de700cd1913e9a028bbe06 383 SUPERFAMILY SSF103473 3 370 1.14E-42 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS08535 8a228f0715de700cd1913e9a028bbe06 383 Gene3D G3DSA:1.20.1250.20 3 179 1.3E-16 T 26-04-2017 A4V04_RS08535 8a228f0715de700cd1913e9a028bbe06 383 Gene3D G3DSA:1.20.1250.20 198 367 6.9E-18 T 26-04-2017 A4V04_RS08535 8a228f0715de700cd1913e9a028bbe06 383 Pfam PF07690 Major Facilitator Superfamily 18 340 2.0E-28 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS08535 8a228f0715de700cd1913e9a028bbe06 383 PRINTS PR01035 Tetracycline resistance protein signature 324 347 7.6E-5 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS08535 8a228f0715de700cd1913e9a028bbe06 383 PRINTS PR01035 Tetracycline resistance protein signature 29 48 7.6E-5 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS08535 8a228f0715de700cd1913e9a028bbe06 383 PRINTS PR01035 Tetracycline resistance protein signature 122 144 7.6E-5 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS08535 8a228f0715de700cd1913e9a028bbe06 383 PRINTS PR01035 Tetracycline resistance protein signature 263 284 7.6E-5 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS02450 de7ebd412c24620ec592e0fefc1de41c 178 SUPERFAMILY SSF51182 1 174 6.88E-71 T 26-04-2017 IPR011051 RmlC-like cupin domain A4V04_RS02450 de7ebd412c24620ec592e0fefc1de41c 178 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 168 3.0E-54 T 26-04-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A4V04_RS02450 de7ebd412c24620ec592e0fefc1de41c 178 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 173 1.4E-68 T 26-04-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A4V04_RS02450 de7ebd412c24620ec592e0fefc1de41c 178 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 173 1.8E-71 T 26-04-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A4V04_RS02450 de7ebd412c24620ec592e0fefc1de41c 178 Gene3D G3DSA:2.60.120.10 1 174 1.7E-74 T 26-04-2017 IPR014710 RmlC-like jelly roll fold A4V04_RS11540 a9e4d4ca22bd041353047abc4c1794c8 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 548 566 2.5E-8 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS11540 a9e4d4ca22bd041353047abc4c1794c8 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 533 2.5E-8 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS11540 a9e4d4ca22bd041353047abc4c1794c8 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 572 585 2.5E-8 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS11540 a9e4d4ca22bd041353047abc4c1794c8 611 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 482 586 9.8E-12 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS11540 a9e4d4ca22bd041353047abc4c1794c8 611 Pfam PF00512 His Kinase A (phospho-acceptor) domain 372 437 2.9E-8 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS11540 a9e4d4ca22bd041353047abc4c1794c8 611 SMART SM00387 480 588 1.1E-11 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS11540 a9e4d4ca22bd041353047abc4c1794c8 611 SUPERFAMILY SSF55874 442 588 2.1E-23 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS11540 a9e4d4ca22bd041353047abc4c1794c8 611 Gene3D G3DSA:1.10.287.130 371 425 1.6E-6 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS11540 a9e4d4ca22bd041353047abc4c1794c8 611 SUPERFAMILY SSF53850 66 268 6.27E-7 T 26-04-2017 A4V04_RS11540 a9e4d4ca22bd041353047abc4c1794c8 611 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 64 269 3.4E-13 T 26-04-2017 A4V04_RS11540 a9e4d4ca22bd041353047abc4c1794c8 611 Gene3D G3DSA:3.40.190.10 116 215 1.3E-4 T 26-04-2017 A4V04_RS11540 a9e4d4ca22bd041353047abc4c1794c8 611 SUPERFAMILY SSF47384 359 437 8.04E-10 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS11540 a9e4d4ca22bd041353047abc4c1794c8 611 SMART SM00388 369 439 5.5E-5 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS11540 a9e4d4ca22bd041353047abc4c1794c8 611 Gene3D G3DSA:3.30.565.10 426 591 4.9E-24 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS04415 8afde310ea8a850e1bcc79ca7303f28e 413 Pfam PF00375 Sodium:dicarboxylate symporter family 11 395 1.6E-118 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS04415 8afde310ea8a850e1bcc79ca7303f28e 413 PRINTS PR00173 Glutamate-aspartate symporter signature 77 102 4.9E-35 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS04415 8afde310ea8a850e1bcc79ca7303f28e 413 PRINTS PR00173 Glutamate-aspartate symporter signature 350 370 4.9E-35 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS04415 8afde310ea8a850e1bcc79ca7303f28e 413 PRINTS PR00173 Glutamate-aspartate symporter signature 214 233 4.9E-35 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS04415 8afde310ea8a850e1bcc79ca7303f28e 413 PRINTS PR00173 Glutamate-aspartate symporter signature 8 28 4.9E-35 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS04415 8afde310ea8a850e1bcc79ca7303f28e 413 PRINTS PR00173 Glutamate-aspartate symporter signature 188 207 4.9E-35 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS04415 8afde310ea8a850e1bcc79ca7303f28e 413 PRINTS PR00173 Glutamate-aspartate symporter signature 288 314 4.9E-35 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS04415 8afde310ea8a850e1bcc79ca7303f28e 413 PRINTS PR00173 Glutamate-aspartate symporter signature 323 342 4.9E-35 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS04415 8afde310ea8a850e1bcc79ca7303f28e 413 SUPERFAMILY SSF118215 10 397 2.35E-113 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS04415 8afde310ea8a850e1bcc79ca7303f28e 413 Gene3D G3DSA:1.10.3860.10 8 399 5.6E-120 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS03875 f340b0b9a176125e8bdf796d975fabbf 89 Gene3D G3DSA:1.10.287.10 4 89 3.2E-39 T 26-04-2017 IPR009068 S15/NS1, RNA-binding A4V04_RS03875 f340b0b9a176125e8bdf796d975fabbf 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 3.1E-40 T 26-04-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS03875 f340b0b9a176125e8bdf796d975fabbf 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.056 T 26-04-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS03875 f340b0b9a176125e8bdf796d975fabbf 89 SUPERFAMILY SSF47060 4 89 3.24E-35 T 26-04-2017 IPR009068 S15/NS1, RNA-binding A4V04_RS03875 f340b0b9a176125e8bdf796d975fabbf 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 26-04-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS03875 f340b0b9a176125e8bdf796d975fabbf 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 9.0E-30 T 26-04-2017 A4V04_RS03875 f340b0b9a176125e8bdf796d975fabbf 89 SMART SM01387 8 88 4.6E-54 T 26-04-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS03875 f340b0b9a176125e8bdf796d975fabbf 89 Pfam PF00312 Ribosomal protein S15 8 88 1.7E-37 T 26-04-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS03805 73c4950a1e02dfc6a9a143f79851efa9 402 Gene3D G3DSA:3.40.640.10 53 263 1.1E-48 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS03805 73c4950a1e02dfc6a9a143f79851efa9 402 Pfam PF00155 Aminotransferase class I and II 51 396 2.6E-32 T 26-04-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4V04_RS03805 73c4950a1e02dfc6a9a143f79851efa9 402 Gene3D G3DSA:3.90.1150.10 264 399 1.0E-20 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS03805 73c4950a1e02dfc6a9a143f79851efa9 402 SUPERFAMILY SSF53383 35 399 1.48E-80 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS07840 e07b59bf6042c0d137731f252f733995 919 TIGRFAM TIGR01706 NAPA: periplasmic nitrate reductase, large subunit 8 918 0.0 T 26-04-2017 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042128|GO:0042597|GO:0051539|GO:0055114 KEGG: 00910+1.7.99.4 A4V04_RS07840 e07b59bf6042c0d137731f252f733995 919 Gene3D G3DSA:3.40.228.10 364 445 1.7E-44 T 26-04-2017 A4V04_RS07840 e07b59bf6042c0d137731f252f733995 919 Gene3D G3DSA:3.40.228.10 185 297 1.7E-44 T 26-04-2017 A4V04_RS07840 e07b59bf6042c0d137731f252f733995 919 SUPERFAMILY SSF53706 44 625 1.96E-163 T 26-04-2017 A4V04_RS07840 e07b59bf6042c0d137731f252f733995 919 Gene3D G3DSA:3.40.50.740 102 184 5.0E-75 T 26-04-2017 A4V04_RS07840 e07b59bf6042c0d137731f252f733995 919 Gene3D G3DSA:3.40.50.740 690 735 5.0E-75 T 26-04-2017 A4V04_RS07840 e07b59bf6042c0d137731f252f733995 919 Gene3D G3DSA:3.40.50.740 446 621 5.0E-75 T 26-04-2017 A4V04_RS07840 e07b59bf6042c0d137731f252f733995 919 Gene3D G3DSA:2.20.25.90 44 101 6.5E-21 T 26-04-2017 A4V04_RS07840 e07b59bf6042c0d137731f252f733995 919 SUPERFAMILY SSF50692 784 918 5.2E-37 T 26-04-2017 IPR009010 Aspartate decarboxylase-like domain A4V04_RS07840 e07b59bf6042c0d137731f252f733995 919 Gene3D G3DSA:2.40.40.20 794 918 2.7E-41 T 26-04-2017 A4V04_RS07840 e07b59bf6042c0d137731f252f733995 919 Pfam PF00384 Molybdopterin oxidoreductase 102 614 3.8E-76 T 26-04-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS07840 e07b59bf6042c0d137731f252f733995 919 SMART SM00926 45 99 5.5E-17 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS07840 e07b59bf6042c0d137731f252f733995 919 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 47 98 2.4E-18 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS07840 e07b59bf6042c0d137731f252f733995 919 Pfam PF01568 Molydopterin dinucleotide binding domain 804 910 7.6E-25 T 26-04-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4V04_RS00365 f99ea29afc6f5b9bc56b5e733441ec62 422 Pfam PF01546 Peptidase family M20/M25/M40 103 417 3.8E-22 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS00365 f99ea29afc6f5b9bc56b5e733441ec62 422 SUPERFAMILY SSF55031 217 324 1.44E-21 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS00365 f99ea29afc6f5b9bc56b5e733441ec62 422 Gene3D G3DSA:3.40.630.10 328 417 1.0E-68 T 26-04-2017 A4V04_RS00365 f99ea29afc6f5b9bc56b5e733441ec62 422 Gene3D G3DSA:3.40.630.10 5 46 1.0E-68 T 26-04-2017 A4V04_RS00365 f99ea29afc6f5b9bc56b5e733441ec62 422 Gene3D G3DSA:3.40.630.10 84 214 1.0E-68 T 26-04-2017 A4V04_RS00365 f99ea29afc6f5b9bc56b5e733441ec62 422 Gene3D G3DSA:3.30.70.360 219 323 6.8E-24 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS00365 f99ea29afc6f5b9bc56b5e733441ec62 422 PIRSF PIRSF005962 1 421 1.5E-102 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS00365 f99ea29afc6f5b9bc56b5e733441ec62 422 SUPERFAMILY SSF53187 331 417 8.64E-59 T 26-04-2017 A4V04_RS00365 f99ea29afc6f5b9bc56b5e733441ec62 422 SUPERFAMILY SSF53187 84 232 8.64E-59 T 26-04-2017 A4V04_RS00365 f99ea29afc6f5b9bc56b5e733441ec62 422 SUPERFAMILY SSF53187 4 46 8.64E-59 T 26-04-2017 A4V04_RS00365 f99ea29afc6f5b9bc56b5e733441ec62 422 Pfam PF07687 Peptidase dimerisation domain 223 299 8.4E-10 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS00365 f99ea29afc6f5b9bc56b5e733441ec62 422 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 7 408 1.3E-85 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS02365 578fd7402e1647de32231b79682b5313 597 Gene3D G3DSA:1.10.287.130 375 432 2.8E-4 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS02365 578fd7402e1647de32231b79682b5313 597 SUPERFAMILY SSF53850 95 269 1.86E-8 T 26-04-2017 A4V04_RS02365 578fd7402e1647de32231b79682b5313 597 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 488 595 9.5E-11 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS02365 578fd7402e1647de32231b79682b5313 597 Pfam PF00512 His Kinase A (phospho-acceptor) domain 378 443 1.2E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS02365 578fd7402e1647de32231b79682b5313 597 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 88 274 1.2E-15 T 26-04-2017 A4V04_RS02365 578fd7402e1647de32231b79682b5313 597 SMART SM00387 486 596 7.1E-15 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS02365 578fd7402e1647de32231b79682b5313 597 SUPERFAMILY SSF55874 432 594 9.43E-23 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS02365 578fd7402e1647de32231b79682b5313 597 Gene3D G3DSA:3.30.565.10 433 596 1.4E-23 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS02365 578fd7402e1647de32231b79682b5313 597 SUPERFAMILY SSF47384 365 446 2.55E-8 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS02365 578fd7402e1647de32231b79682b5313 597 SMART SM00388 376 446 3.4E-8 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS08700 6e105a3afd15b8a308eef1727175c7bb 268 Gene3D G3DSA:3.60.21.10 162 258 1.3E-44 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS08700 6e105a3afd15b8a308eef1727175c7bb 268 Gene3D G3DSA:3.60.21.10 1 127 1.3E-44 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS08700 6e105a3afd15b8a308eef1727175c7bb 268 SUPERFAMILY SSF56300 1 247 7.6E-47 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS08700 6e105a3afd15b8a308eef1727175c7bb 268 Pfam PF00149 Calcineurin-like phosphoesterase 2 156 6.7E-15 T 26-04-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4V04_RS08700 6e105a3afd15b8a308eef1727175c7bb 268 PIRSF PIRSF000903 1 264 1.8E-85 T 26-04-2017 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 A4V04_RS09860 c53088c8c37457addda9a1f8b25fa30b 222 Gene3D G3DSA:3.30.70.20 167 215 2.9E-28 T 26-04-2017 A4V04_RS09860 c53088c8c37457addda9a1f8b25fa30b 222 Gene3D G3DSA:3.30.70.20 39 98 2.9E-28 T 26-04-2017 A4V04_RS09860 c53088c8c37457addda9a1f8b25fa30b 222 SUPERFAMILY SSF54862 37 216 6.8E-55 T 26-04-2017 A4V04_RS09860 c53088c8c37457addda9a1f8b25fa30b 222 Gene3D G3DSA:3.30.70.20 99 130 4.2E-11 T 26-04-2017 A4V04_RS09860 c53088c8c37457addda9a1f8b25fa30b 222 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 126 137 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS09860 c53088c8c37457addda9a1f8b25fa30b 222 Pfam PF13247 4Fe-4S dicluster domain 88 182 5.6E-21 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS09860 c53088c8c37457addda9a1f8b25fa30b 222 Pfam PF00037 4Fe-4S binding domain 42 58 4.9E-5 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS09860 c53088c8c37457addda9a1f8b25fa30b 222 Gene3D G3DSA:3.30.70.20 131 166 1.4E-11 T 26-04-2017 A4V04_RS01980 7b57524c15cf4928807f715d70f92d3e 394 SUPERFAMILY SSF47384 171 240 1.67E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS01980 7b57524c15cf4928807f715d70f92d3e 394 Pfam PF00512 His Kinase A (phospho-acceptor) domain 178 241 1.8E-8 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS01980 7b57524c15cf4928807f715d70f92d3e 394 Gene3D G3DSA:1.10.287.130 175 239 3.1E-6 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS01980 7b57524c15cf4928807f715d70f92d3e 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 323 337 8.8E-7 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS01980 7b57524c15cf4928807f715d70f92d3e 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 370 8.8E-7 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS01980 7b57524c15cf4928807f715d70f92d3e 394 SUPERFAMILY SSF55874 230 390 3.14E-23 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS01980 7b57524c15cf4928807f715d70f92d3e 394 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 288 390 5.1E-13 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS01980 7b57524c15cf4928807f715d70f92d3e 394 Gene3D G3DSA:3.30.565.10 247 392 8.8E-24 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS01980 7b57524c15cf4928807f715d70f92d3e 394 SMART SM00387 283 392 2.5E-15 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS01980 7b57524c15cf4928807f715d70f92d3e 394 SMART SM00388 174 244 1.5E-6 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10235 7c078d5e5bca3a1aeab26dd7dcdb35a7 316 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 6 315 49.333 T 26-04-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4V04_RS10235 7c078d5e5bca3a1aeab26dd7dcdb35a7 316 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 314 4.5E-123 T 26-04-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4V04_RS10235 7c078d5e5bca3a1aeab26dd7dcdb35a7 316 SMART SM01400 6 123 5.5E-80 T 26-04-2017 A4V04_RS10235 7c078d5e5bca3a1aeab26dd7dcdb35a7 316 Pfam PF14572 Phosphoribosyl synthetase-associated domain 205 314 1.9E-27 T 26-04-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4V04_RS10235 7c078d5e5bca3a1aeab26dd7dcdb35a7 316 SUPERFAMILY SSF53271 13 101 6.02E-6 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS10235 7c078d5e5bca3a1aeab26dd7dcdb35a7 316 Gene3D G3DSA:3.40.50.2020 4 161 9.9E-76 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS10235 7c078d5e5bca3a1aeab26dd7dcdb35a7 316 SUPERFAMILY SSF53271 71 304 6.42E-64 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS10235 7c078d5e5bca3a1aeab26dd7dcdb35a7 316 Gene3D G3DSA:3.40.50.2020 162 289 1.0E-53 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS10235 7c078d5e5bca3a1aeab26dd7dcdb35a7 316 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 131 146 - T 26-04-2017 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 A4V04_RS10235 7c078d5e5bca3a1aeab26dd7dcdb35a7 316 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 123 1.9E-50 T 26-04-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4V04_RS01015 6ffdc80e862d159ce71da52aeecc77e8 202 Pfam PF04011 LemA family 7 195 3.8E-59 T 26-04-2017 IPR007156 LemA A4V04_RS01015 6ffdc80e862d159ce71da52aeecc77e8 202 SUPERFAMILY SSF140478 26 183 2.62E-49 T 26-04-2017 IPR023353 LemA-like domain A4V04_RS01015 6ffdc80e862d159ce71da52aeecc77e8 202 Gene3D G3DSA:1.20.1440.20 18 195 3.8E-57 T 26-04-2017 IPR023353 LemA-like domain A4V04_RS08170 5f2e2213963ceb3a03b4a69f2ccf9643 1328 Pfam PF13116 Protein of unknown function 549 843 9.6E-51 T 26-04-2017 IPR025263 Domain of unknown function DUF3971 A4V04_RS08170 5f2e2213963ceb3a03b4a69f2ccf9643 1328 Pfam PF13502 AsmA-like C-terminal region 1071 1317 3.8E-56 T 26-04-2017 IPR032712 AsmA-like, C-terminal A4V04_RS08170 5f2e2213963ceb3a03b4a69f2ccf9643 1328 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 27 1326 5.1E-196 T 26-04-2017 IPR011836 Conserved hypothetical protein CHP02099 A4V04_RS02405 76d95eedf982a42a06dde5598e8d168f 369 Pfam PF03466 LysR substrate binding domain 111 212 5.6E-12 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS02405 76d95eedf982a42a06dde5598e8d168f 369 SUPERFAMILY SSF53850 111 215 9.1E-14 T 26-04-2017 A4V04_RS02405 76d95eedf982a42a06dde5598e8d168f 369 SUPERFAMILY SSF46785 17 122 3.32E-11 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02405 76d95eedf982a42a06dde5598e8d168f 369 Gene3D G3DSA:3.40.190.10 197 306 8.3E-4 T 26-04-2017 A4V04_RS02405 76d95eedf982a42a06dde5598e8d168f 369 Gene3D G3DSA:3.40.190.10 114 196 5.4E-12 T 26-04-2017 A4V04_RS02405 76d95eedf982a42a06dde5598e8d168f 369 Gene3D G3DSA:1.10.10.10 25 108 5.4E-12 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02405 76d95eedf982a42a06dde5598e8d168f 369 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 27 79 6.5E-10 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS13030 03523f56c8bd157df6fdb1f4921771e0 524 Pfam PF02384 N-6 DNA Methylase 173 486 2.9E-108 T 26-04-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A4V04_RS13030 03523f56c8bd157df6fdb1f4921771e0 524 Pfam PF12161 HsdM N-terminal domain 9 163 4.0E-20 T 26-04-2017 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain A4V04_RS13030 03523f56c8bd157df6fdb1f4921771e0 524 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 306 312 - T 26-04-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4V04_RS13030 03523f56c8bd157df6fdb1f4921771e0 524 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 6 501 2.1E-112 T 26-04-2017 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 A4V04_RS13030 03523f56c8bd157df6fdb1f4921771e0 524 Gene3D G3DSA:3.40.50.150 198 430 4.6E-39 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS13030 03523f56c8bd157df6fdb1f4921771e0 524 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 303 315 1.0E-21 T 26-04-2017 A4V04_RS13030 03523f56c8bd157df6fdb1f4921771e0 524 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 196 212 1.0E-21 T 26-04-2017 A4V04_RS13030 03523f56c8bd157df6fdb1f4921771e0 524 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 224 238 1.0E-21 T 26-04-2017 A4V04_RS13030 03523f56c8bd157df6fdb1f4921771e0 524 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 339 363 1.0E-21 T 26-04-2017 A4V04_RS13030 03523f56c8bd157df6fdb1f4921771e0 524 SUPERFAMILY SSF53335 88 521 1.37E-129 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS13030 03523f56c8bd157df6fdb1f4921771e0 524 SUPERFAMILY SSF53335 8 46 1.37E-129 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 SUPERFAMILY SSF47384 224 295 1.75E-10 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 SMART SM00388 239 298 6.3E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 SUPERFAMILY SSF55874 295 456 2.36E-28 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 SMART SM00304 186 238 2.5E-7 T 26-04-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 SUPERFAMILY SSF158472 187 236 1.7E-6 T 26-04-2017 A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 451 7.7E-9 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 394 7.7E-9 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 7.7E-9 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 SMART SM00387 338 454 2.1E-23 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 452 2.4E-14 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 Gene3D G3DSA:3.30.565.10 302 453 1.9E-28 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 Pfam PF00512 His Kinase A (phospho-acceptor) domain 242 296 4.4E-8 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 Gene3D G3DSA:1.10.287.130 229 293 2.7E-13 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 Pfam PF00672 HAMP domain 168 234 1.8E-11 T 26-04-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4V04_RS05400 ebeee80bc1c69344855cd7c184ba24a0 466 Pfam PF16524 Periplasmic domain of Sensor histidine kinase RisS 52 155 1.0E-33 T 26-04-2017 IPR032408 Sensor histidine kinase RisS, periplasmic domain A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 Pfam PF14520 Helix-hairpin-helix domain 105 155 1.9E-8 T 26-04-2017 A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 Pfam PF13538 UvrD-like helicase C-terminal domain 658 705 3.9E-18 T 26-04-2017 IPR027785 UvrD-like helicase C-terminal domain A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 SUPERFAMILY SSF52540 558 718 1.26E-59 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 SUPERFAMILY SSF52540 449 514 1.26E-59 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 SUPERFAMILY SSF52540 197 496 4.81E-50 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 Gene3D G3DSA:1.10.150.20 106 151 4.0E-5 T 26-04-2017 A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 21 730 1.4E-219 T 26-04-2017 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 17 730 28.0 T 26-04-2017 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 SMART SM00278 198 217 310.0 T 26-04-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 SMART SM00278 134 153 0.44 T 26-04-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 Gene3D G3DSA:3.40.50.300 298 514 4.0E-51 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 SMART SM00382 351 492 2.2E-4 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 Gene3D G3DSA:3.40.50.300 659 709 3.7E-17 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 SUPERFAMILY SSF47781 91 156 2.97E-11 T 26-04-2017 IPR010994 RuvA domain 2-like A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 Pfam PF13604 AAA domain 338 515 7.0E-46 T 26-04-2017 A4V04_RS04065 8d2c2975cdac6a7c2248208b3bec13a5 733 Pfam PF14490 Helix-hairpin-helix containing domain 157 247 9.4E-29 T 26-04-2017 IPR029493 RecD helicase-like helix-hairpin-helix domain A4V04_RS02155 b82327d3698f6c897e2a56f54e1ee5aa 584 SMART SM00387 470 579 3.2E-12 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS02155 b82327d3698f6c897e2a56f54e1ee5aa 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 538 556 6.2E-8 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS02155 b82327d3698f6c897e2a56f54e1ee5aa 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 525 6.2E-8 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS02155 b82327d3698f6c897e2a56f54e1ee5aa 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 563 576 6.2E-8 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS02155 b82327d3698f6c897e2a56f54e1ee5aa 584 Pfam PF00512 His Kinase A (phospho-acceptor) domain 363 428 5.7E-8 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS02155 b82327d3698f6c897e2a56f54e1ee5aa 584 SMART SM00388 360 430 1.5E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS02155 b82327d3698f6c897e2a56f54e1ee5aa 584 SUPERFAMILY SSF55874 416 580 9.56E-20 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS02155 b82327d3698f6c897e2a56f54e1ee5aa 584 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 37 256 2.5E-24 T 26-04-2017 A4V04_RS02155 b82327d3698f6c897e2a56f54e1ee5aa 584 Gene3D G3DSA:3.40.190.10 112 191 4.5E-5 T 26-04-2017 A4V04_RS02155 b82327d3698f6c897e2a56f54e1ee5aa 584 Gene3D G3DSA:1.10.287.130 362 415 6.0E-7 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS02155 b82327d3698f6c897e2a56f54e1ee5aa 584 SUPERFAMILY SSF53850 45 262 9.32E-13 T 26-04-2017 A4V04_RS02155 b82327d3698f6c897e2a56f54e1ee5aa 584 SUPERFAMILY SSF47384 352 429 1.65E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS02155 b82327d3698f6c897e2a56f54e1ee5aa 584 Gene3D G3DSA:3.30.565.10 416 582 1.6E-22 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS02155 b82327d3698f6c897e2a56f54e1ee5aa 584 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 475 577 1.1E-11 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS11940 a58624b0c0703e684aced01ebab494e9 257 Gene3D G3DSA:2.60.440.10 176 255 2.0E-19 T 26-04-2017 IPR027462 Z ring-associated protein D, C-terminal domain A4V04_RS11940 a58624b0c0703e684aced01ebab494e9 257 Pfam PF07072 Protein of unknown function (DUF1342) 20 229 3.9E-67 T 26-04-2017 IPR009777 Cell division protein ZapD A4V04_RS11940 a58624b0c0703e684aced01ebab494e9 257 Gene3D G3DSA:1.10.3900.10 14 175 1.2E-54 T 26-04-2017 A4V04_RS11940 a58624b0c0703e684aced01ebab494e9 257 Hamap MF_01092 Cell division protein ZapD [zapD]. 5 255 29.061 T 26-04-2017 IPR009777 Cell division protein ZapD A4V04_RS11940 a58624b0c0703e684aced01ebab494e9 257 SUPERFAMILY SSF160950 5 255 1.96E-71 T 26-04-2017 A4V04_RS01175 b27c0c8fc85aad78deaaaccc475d595d 552 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 550 4.6E-143 T 26-04-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A4V04_RS01175 b27c0c8fc85aad78deaaaccc475d595d 552 Gene3D G3DSA:3.40.50.300 1 204 1.8E-52 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01175 b27c0c8fc85aad78deaaaccc475d595d 552 Gene3D G3DSA:3.40.50.300 344 497 2.9E-7 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01175 b27c0c8fc85aad78deaaaccc475d595d 552 SMART SM00382 21 522 0.0023 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS01175 b27c0c8fc85aad78deaaaccc475d595d 552 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 507 1.2E-17 T 26-04-2017 IPR003395 RecF/RecN/SMC, N-terminal A4V04_RS01175 b27c0c8fc85aad78deaaaccc475d595d 552 PIRSF PIRSF003128 1 552 5.6E-145 T 26-04-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A4V04_RS01175 b27c0c8fc85aad78deaaaccc475d595d 552 SUPERFAMILY SSF52540 1 198 4.41E-56 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01175 b27c0c8fc85aad78deaaaccc475d595d 552 SUPERFAMILY SSF52540 285 313 4.41E-56 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01175 b27c0c8fc85aad78deaaaccc475d595d 552 SUPERFAMILY SSF52540 341 503 4.41E-56 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 SUPERFAMILY SSF54106 316 361 9.16E-6 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 SUPERFAMILY SSF53955 85 234 1.83E-40 T 26-04-2017 IPR023346 Lysozyme-like domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 SUPERFAMILY SSF54106 391 435 3.66E-9 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 Gene3D G3DSA:3.10.350.10 315 361 1.1E-8 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 Gene3D G3DSA:3.10.350.10 539 582 3.5E-16 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 Gene3D G3DSA:3.10.350.10 391 435 5.7E-14 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 Gene3D G3DSA:3.10.350.10 463 506 6.4E-16 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 SUPERFAMILY SSF54106 463 506 2.49E-10 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 SMART SM00257 540 583 1.3E-14 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 SMART SM00257 392 435 1.5E-10 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 SMART SM00257 318 362 6.3E-6 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 SMART SM00257 464 507 4.4E-13 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 SUPERFAMILY SSF54106 539 582 2.09E-10 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 Pfam PF01476 LysM domain 393 434 1.6E-10 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 Pfam PF01476 LysM domain 465 506 9.6E-12 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 Pfam PF01476 LysM domain 541 582 4.5E-13 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 Pfam PF01476 LysM domain 319 361 2.4E-5 T 26-04-2017 IPR018392 LysM domain A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 Gene3D G3DSA:1.10.530.10 82 239 9.2E-47 T 26-04-2017 A4V04_RS01200 c34603a1c28664cf815a72ba2ace1cf6 583 Pfam PF01464 Transglycosylase SLT domain 97 197 1.1E-25 T 26-04-2017 IPR008258 Transglycosylase SLT domain 1 A4V04_RS01040 9b871b10a356ca71354786e581f19241 290 Gene3D G3DSA:3.10.290.10 13 69 5.9E-17 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS01040 9b871b10a356ca71354786e581f19241 290 Pfam PF00849 RNA pseudouridylate synthase 75 224 9.7E-13 T 26-04-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS01040 9b871b10a356ca71354786e581f19241 290 SUPERFAMILY SSF55120 73 257 1.55E-33 T 26-04-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS01040 9b871b10a356ca71354786e581f19241 290 SMART SM00363 13 70 2.5E-5 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS01040 9b871b10a356ca71354786e581f19241 290 Pfam PF01479 S4 domain 14 58 1.8E-6 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS01040 9b871b10a356ca71354786e581f19241 290 SUPERFAMILY SSF55174 13 110 1.19E-14 T 26-04-2017 A4V04_RS01040 9b871b10a356ca71354786e581f19241 290 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 93 254 4.1E-36 T 26-04-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A4V04_RS07280 66af26da9772d4e55faa34822d629d3e 153 SUPERFAMILY SSF143422 10 134 3.79E-40 T 26-04-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS07280 66af26da9772d4e55faa34822d629d3e 153 Pfam PF01797 Transposase IS200 like 15 133 1.5E-32 T 26-04-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS07280 66af26da9772d4e55faa34822d629d3e 153 Gene3D G3DSA:3.30.70.1290 9 135 5.7E-40 T 26-04-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS07280 66af26da9772d4e55faa34822d629d3e 153 SMART SM01321 14 133 1.6E-32 T 26-04-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 Pfam PF06071 Protein of unknown function (DUF933) 280 363 7.1E-40 T 26-04-2017 IPR013029 Domain of unknown function DUF933 A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 Pfam PF01926 50S ribosome-binding GTPase 5 121 4.6E-23 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 SUPERFAMILY SSF81271 280 360 3.49E-36 T 26-04-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 Gene3D G3DSA:1.10.150.300 131 201 1.5E-28 T 26-04-2017 IPR023192 TGS-like domain A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 364 5.1E-159 T 26-04-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 Gene3D G3DSA:3.40.50.300 202 267 1.1E-44 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 Gene3D G3DSA:3.40.50.300 4 130 1.1E-44 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 PIRSF PIRSF006641 1 364 8.3E-158 T 26-04-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.9E-34 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.9E-34 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.9E-34 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.9E-34 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 364 44.909 T 26-04-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 SUPERFAMILY SSF52540 3 299 9.92E-86 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10260 80c3d085afa7a68f609ee7392e8ee45a 364 Gene3D G3DSA:3.10.20.30 268 364 4.5E-50 T 26-04-2017 IPR012675 Beta-grasp domain A4V04_RS03155 a6e11078148985a05d14b8d0142cb5ec 259 SUPERFAMILY SSF52343 111 244 5.76E-25 T 26-04-2017 A4V04_RS03155 a6e11078148985a05d14b8d0142cb5ec 259 SUPERFAMILY SSF63380 7 97 4.48E-17 T 26-04-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A4V04_RS03155 a6e11078148985a05d14b8d0142cb5ec 259 PRINTS PR00410 Phenol hydroxylase reductase family signature 220 228 7.4E-6 T 26-04-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 A4V04_RS03155 a6e11078148985a05d14b8d0142cb5ec 259 PRINTS PR00410 Phenol hydroxylase reductase family signature 117 136 7.4E-6 T 26-04-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 A4V04_RS03155 a6e11078148985a05d14b8d0142cb5ec 259 PRINTS PR00410 Phenol hydroxylase reductase family signature 34 46 7.4E-6 T 26-04-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 A4V04_RS03155 a6e11078148985a05d14b8d0142cb5ec 259 Gene3D G3DSA:3.40.50.80 103 259 3.5E-33 T 26-04-2017 A4V04_RS03155 a6e11078148985a05d14b8d0142cb5ec 259 Gene3D G3DSA:2.40.30.10 5 97 3.4E-20 T 26-04-2017 A4V04_RS03155 a6e11078148985a05d14b8d0142cb5ec 259 Pfam PF08022 FAD-binding domain 12 78 9.1E-6 T 26-04-2017 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 A4V04_RS03155 a6e11078148985a05d14b8d0142cb5ec 259 Pfam PF00175 Oxidoreductase NAD-binding domain 119 234 6.4E-8 T 26-04-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4V04_RS11735 8dcee9ef1bd36748a24ec77964d484b5 505 SUPERFAMILY SSF53335 267 368 1.86E-64 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS11735 8dcee9ef1bd36748a24ec77964d484b5 505 SUPERFAMILY SSF53335 36 215 1.86E-64 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS11735 8dcee9ef1bd36748a24ec77964d484b5 505 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 61 73 8.7E-20 T 26-04-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 A4V04_RS11735 8dcee9ef1bd36748a24ec77964d484b5 505 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 95 114 8.7E-20 T 26-04-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 A4V04_RS11735 8dcee9ef1bd36748a24ec77964d484b5 505 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 322 336 8.7E-20 T 26-04-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 A4V04_RS11735 8dcee9ef1bd36748a24ec77964d484b5 505 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 299 321 8.7E-20 T 26-04-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 A4V04_RS11735 8dcee9ef1bd36748a24ec77964d484b5 505 PIRSF PIRSF015855 3 492 2.7E-105 T 26-04-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 A4V04_RS11735 8dcee9ef1bd36748a24ec77964d484b5 505 Pfam PF01555 DNA methylase 61 352 3.0E-50 T 26-04-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A4V04_RS11735 8dcee9ef1bd36748a24ec77964d484b5 505 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 64 70 - T 26-04-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4V04_RS11735 8dcee9ef1bd36748a24ec77964d484b5 505 Gene3D G3DSA:3.40.50.150 38 191 7.0E-71 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS11735 8dcee9ef1bd36748a24ec77964d484b5 505 Gene3D G3DSA:3.40.50.150 251 389 7.0E-71 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS05875 5995effa720094bf20314c3178bcc2ad 389 PIRSF PIRSF006205 1 388 8.8E-146 T 26-04-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A4V04_RS05875 5995effa720094bf20314c3178bcc2ad 389 SUPERFAMILY SSF51735 2 150 9.7E-41 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS05875 5995effa720094bf20314c3178bcc2ad 389 Pfam PF13288 DXP reductoisomerase C-terminal domain 261 376 3.7E-39 T 26-04-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A4V04_RS05875 5995effa720094bf20314c3178bcc2ad 389 SUPERFAMILY SSF69055 292 384 4.32E-28 T 26-04-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A4V04_RS05875 5995effa720094bf20314c3178bcc2ad 389 Gene3D G3DSA:1.10.1740.10 303 384 2.2E-26 T 26-04-2017 A4V04_RS05875 5995effa720094bf20314c3178bcc2ad 389 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 382 2.3E-141 T 26-04-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A4V04_RS05875 5995effa720094bf20314c3178bcc2ad 389 Gene3D G3DSA:3.40.50.720 1 150 1.0E-46 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS05875 5995effa720094bf20314c3178bcc2ad 389 SUPERFAMILY SSF55347 126 264 3.6E-57 T 26-04-2017 A4V04_RS05875 5995effa720094bf20314c3178bcc2ad 389 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 229 1.1E-37 T 26-04-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A4V04_RS05875 5995effa720094bf20314c3178bcc2ad 389 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 1.2E-36 T 26-04-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A4V04_RS05875 5995effa720094bf20314c3178bcc2ad 389 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 382 43.731 T 26-04-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A4V04_RS07545 520d38337dd47854ae11131017dec64f 350 Pfam PF13609 Gram-negative porin 7 319 7.5E-37 T 26-04-2017 A4V04_RS07545 520d38337dd47854ae11131017dec64f 350 Gene3D G3DSA:2.40.160.10 21 350 1.4E-59 T 26-04-2017 IPR023614 Porin domain A4V04_RS07545 520d38337dd47854ae11131017dec64f 350 PRINTS PR00184 Neisseria sp. porin signature 52 77 5.7E-8 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS07545 520d38337dd47854ae11131017dec64f 350 PRINTS PR00184 Neisseria sp. porin signature 295 319 5.7E-8 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS07545 520d38337dd47854ae11131017dec64f 350 SUPERFAMILY SSF56935 21 350 1.25E-44 T 26-04-2017 A4V04_RS13045 531e7286d078037e61390c62aeedd998 208 SUPERFAMILY SSF52172 16 135 3.27E-28 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS13045 531e7286d078037e61390c62aeedd998 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 193 1.8E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS13045 531e7286d078037e61390c62aeedd998 208 Gene3D G3DSA:1.10.10.10 149 193 1.0E-13 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS13045 531e7286d078037e61390c62aeedd998 208 Gene3D G3DSA:3.40.50.2300 15 148 2.5E-28 T 26-04-2017 A4V04_RS13045 531e7286d078037e61390c62aeedd998 208 SUPERFAMILY SSF46894 141 196 2.35E-11 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS13045 531e7286d078037e61390c62aeedd998 208 SMART SM00421 146 203 7.0E-8 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS13045 531e7286d078037e61390c62aeedd998 208 SMART SM00448 12 123 2.0E-23 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS13045 531e7286d078037e61390c62aeedd998 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS13045 531e7286d078037e61390c62aeedd998 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 1.1E-8 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS13045 531e7286d078037e61390c62aeedd998 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 1.1E-8 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS13045 531e7286d078037e61390c62aeedd998 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 1.1E-8 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS13045 531e7286d078037e61390c62aeedd998 208 Pfam PF00072 Response regulator receiver domain 15 124 6.7E-23 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS08850 57036958356f435dfbb61ea36cf76a2b 429 SUPERFAMILY SSF82544 8 428 6.67E-125 T 26-04-2017 A4V04_RS08850 57036958356f435dfbb61ea36cf76a2b 429 Pfam PF13660 Domain of unknown function (DUF4147) 14 235 3.3E-71 T 26-04-2017 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 A4V04_RS08850 57036958356f435dfbb61ea36cf76a2b 429 Pfam PF05161 MOFRL family 316 422 2.0E-31 T 26-04-2017 IPR007835 MOFRL domain Reactome: R-HSA-70350 A4V04_RS08850 57036958356f435dfbb61ea36cf76a2b 429 Gene3D G3DSA:3.40.50.10180 12 251 1.1E-85 T 26-04-2017 A4V04_RS08850 57036958356f435dfbb61ea36cf76a2b 429 Gene3D G3DSA:3.40.1480.10 252 428 1.8E-53 T 26-04-2017 IPR007835 MOFRL domain Reactome: R-HSA-70350 A4V04_RS10380 5b8f476e7c951e6f0cbb003e933dffae 601 SUPERFAMILY SSF53850 71 276 4.08E-16 T 26-04-2017 A4V04_RS10380 5b8f476e7c951e6f0cbb003e933dffae 601 Gene3D G3DSA:3.40.190.10 65 141 2.1E-4 T 26-04-2017 A4V04_RS10380 5b8f476e7c951e6f0cbb003e933dffae 601 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 75 291 4.4E-25 T 26-04-2017 A4V04_RS10380 5b8f476e7c951e6f0cbb003e933dffae 601 SMART SM00388 375 445 7.1E-5 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10380 5b8f476e7c951e6f0cbb003e933dffae 601 SUPERFAMILY SSF47384 362 443 1.06E-6 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10380 5b8f476e7c951e6f0cbb003e933dffae 601 Gene3D G3DSA:3.30.565.10 446 593 1.9E-28 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10380 5b8f476e7c951e6f0cbb003e933dffae 601 SMART SM00387 486 595 8.9E-17 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10380 5b8f476e7c951e6f0cbb003e933dffae 601 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 486 593 1.3E-9 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10380 5b8f476e7c951e6f0cbb003e933dffae 601 SUPERFAMILY SSF55874 435 594 2.75E-27 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10380 5b8f476e7c951e6f0cbb003e933dffae 601 Gene3D G3DSA:3.40.190.10 142 217 1.1E-4 T 26-04-2017 A4V04_RS04080 c1b6bab498dc7bea9481897ef8c3cbf1 329 PIRSF PIRSF000355 2 323 7.4E-86 T 26-04-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4V04_RS04080 c1b6bab498dc7bea9481897ef8c3cbf1 329 SUPERFAMILY SSF47240 14 324 7.63E-81 T 26-04-2017 IPR009078 Ferritin-like superfamily A4V04_RS04080 c1b6bab498dc7bea9481897ef8c3cbf1 329 Pfam PF00268 Ribonucleotide reductase, small chain 12 288 4.7E-72 T 26-04-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4V04_RS04080 c1b6bab498dc7bea9481897ef8c3cbf1 329 Gene3D G3DSA:1.10.620.20 11 292 3.2E-92 T 26-04-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 A4V04_RS03920 826183a234552faf909237c07ec43728 308 SUPERFAMILY SSF53686 2 307 1.7E-105 T 26-04-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4V04_RS03920 826183a234552faf909237c07ec43728 308 Gene3D G3DSA:3.40.50.1100 40 136 1.6E-39 T 26-04-2017 A4V04_RS03920 826183a234552faf909237c07ec43728 308 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 294 7.1E-76 T 26-04-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4V04_RS03920 826183a234552faf909237c07ec43728 308 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 307 1.7E-128 T 26-04-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A4V04_RS03920 826183a234552faf909237c07ec43728 308 Gene3D G3DSA:3.40.50.1100 137 307 7.4E-79 T 26-04-2017 A4V04_RS03920 826183a234552faf909237c07ec43728 308 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 35 53 - T 26-04-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A4V04_RS03920 826183a234552faf909237c07ec43728 308 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 307 1.8E-132 T 26-04-2017 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A4V04_RS12480 c71ad2b5c8d67c46c2d016370ed70d1f 462 SUPERFAMILY SSF56425 280 399 1.36E-20 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS12480 c71ad2b5c8d67c46c2d016370ed70d1f 462 Gene3D G3DSA:3.90.700.10 283 390 3.3E-15 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS12480 c71ad2b5c8d67c46c2d016370ed70d1f 462 SUPERFAMILY SSF51905 27 275 1.27E-54 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12480 c71ad2b5c8d67c46c2d016370ed70d1f 462 SUPERFAMILY SSF51905 400 459 1.27E-54 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12480 c71ad2b5c8d67c46c2d016370ed70d1f 462 Gene3D G3DSA:3.50.50.60 395 458 9.1E-80 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12480 c71ad2b5c8d67c46c2d016370ed70d1f 462 Gene3D G3DSA:3.50.50.60 29 258 9.1E-80 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12480 c71ad2b5c8d67c46c2d016370ed70d1f 462 Pfam PF00890 FAD binding domain 32 439 9.5E-58 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS12480 c71ad2b5c8d67c46c2d016370ed70d1f 462 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 32 451 2.8E-90 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS10610 2e91ab4acaf92893f53f183948b1be4e 329 Gene3D G3DSA:3.40.190.10 259 318 1.2E-36 T 26-04-2017 A4V04_RS10610 2e91ab4acaf92893f53f183948b1be4e 329 Gene3D G3DSA:3.40.190.10 2 118 1.2E-36 T 26-04-2017 A4V04_RS10610 2e91ab4acaf92893f53f183948b1be4e 329 SUPERFAMILY SSF53850 23 323 5.8E-69 T 26-04-2017 A4V04_RS10610 2e91ab4acaf92893f53f183948b1be4e 329 Pfam PF13343 Bacterial extracellular solute-binding protein 70 301 6.5E-30 T 26-04-2017 A4V04_RS10610 2e91ab4acaf92893f53f183948b1be4e 329 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 237 256 4.9E-5 T 26-04-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A4V04_RS10610 2e91ab4acaf92893f53f183948b1be4e 329 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 44 65 4.9E-5 T 26-04-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A4V04_RS10610 2e91ab4acaf92893f53f183948b1be4e 329 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 141 155 4.9E-5 T 26-04-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A4V04_RS10610 2e91ab4acaf92893f53f183948b1be4e 329 Gene3D G3DSA:3.40.190.10 123 258 2.4E-34 T 26-04-2017 A4V04_RS10610 2e91ab4acaf92893f53f183948b1be4e 329 PIRSF PIRSF002825 2 327 1.6E-66 T 26-04-2017 IPR026045 Ferric binding protein A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 Gene3D G3DSA:3.40.50.261 290 430 2.3E-9 T 26-04-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 SUPERFAMILY SSF51735 5 139 4.24E-25 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 SUPERFAMILY SSF52210 132 290 2.49E-25 T 26-04-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 SUPERFAMILY SSF56059 490 698 1.0E-21 T 26-04-2017 A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 Pfam PF13302 Acetyltransferase (GNAT) domain 735 871 2.3E-8 T 26-04-2017 IPR000182 GNAT domain GO:0008080 A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 Pfam PF13549 ATP-grasp domain 479 698 1.2E-49 T 26-04-2017 A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 Gene3D G3DSA:3.30.470.20 492 571 1.3E-4 T 26-04-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 SMART SM00881 10 104 3.6E-15 T 26-04-2017 IPR003781 CoA-binding GO:0048037 A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 Gene3D G3DSA:3.40.50.261 133 289 4.5E-19 T 26-04-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 153 290 3.8E-31 T 26-04-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 Gene3D G3DSA:3.40.630.30 737 875 7.6E-14 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 Gene3D G3DSA:3.40.50.720 6 132 1.3E-25 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 SUPERFAMILY SSF55729 734 877 3.78E-18 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 SUPERFAMILY SSF52210 298 438 5.76E-16 T 26-04-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS08950 2b05d31501f4d924bd909dec5fbae745 895 Pfam PF13380 CoA binding domain 14 135 4.4E-17 T 26-04-2017 IPR003781 CoA-binding GO:0048037 A4V04_RS10250 2cc62a04d6b67d89f5712e42a1c975ab 198 SUPERFAMILY SSF53178 9 197 1.44E-59 T 26-04-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4V04_RS10250 2cc62a04d6b67d89f5712e42a1c975ab 198 Gene3D G3DSA:3.40.50.1470 7 197 7.7E-63 T 26-04-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4V04_RS10250 2cc62a04d6b67d89f5712e42a1c975ab 198 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 116 126 - T 26-04-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 A4V04_RS10250 2cc62a04d6b67d89f5712e42a1c975ab 198 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 9 197 2.4E-57 T 26-04-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4V04_RS10250 2cc62a04d6b67d89f5712e42a1c975ab 198 Pfam PF01195 Peptidyl-tRNA hydrolase 11 194 1.8E-50 T 26-04-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4V04_RS10250 2cc62a04d6b67d89f5712e42a1c975ab 198 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 9 190 33.833 T 26-04-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4V04_RS02895 0f05deef571cec40fa68571f5422ae3f 408 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 245 9.5E-55 T 26-04-2017 IPR014030 Beta-ketoacyl synthase, N-terminal A4V04_RS02895 0f05deef571cec40fa68571f5422ae3f 408 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 365 2.3E-34 T 26-04-2017 IPR014031 Beta-ketoacyl synthase, C-terminal A4V04_RS02895 0f05deef571cec40fa68571f5422ae3f 408 Gene3D G3DSA:3.40.47.10 262 406 2.7E-58 T 26-04-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4V04_RS02895 0f05deef571cec40fa68571f5422ae3f 408 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 2 405 7.6E-188 T 26-04-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A4V04_RS02895 0f05deef571cec40fa68571f5422ae3f 408 SMART SM00825 Beta-ketoacyl synthase 4 408 2.3E-16 T 26-04-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4V04_RS02895 0f05deef571cec40fa68571f5422ae3f 408 SUPERFAMILY SSF53901 212 407 1.07E-70 T 26-04-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4V04_RS02895 0f05deef571cec40fa68571f5422ae3f 408 Gene3D G3DSA:3.40.47.10 1 258 1.5E-74 T 26-04-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4V04_RS02895 0f05deef571cec40fa68571f5422ae3f 408 PIRSF PIRSF000447 1 408 3.3E-171 T 26-04-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A4V04_RS02895 0f05deef571cec40fa68571f5422ae3f 408 SUPERFAMILY SSF53901 1 250 1.15E-77 T 26-04-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4V04_RS08595 56f47b644c02e049f1edbf51cefc8e60 226 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 109 225 8.2E-33 T 26-04-2017 IPR014162 Tol-Pal system, YbgF A4V04_RS08595 56f47b644c02e049f1edbf51cefc8e60 226 Gene3D G3DSA:1.25.40.10 116 220 1.4E-13 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS08595 56f47b644c02e049f1edbf51cefc8e60 226 SUPERFAMILY SSF48452 115 223 3.16E-14 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS08595 56f47b644c02e049f1edbf51cefc8e60 226 Pfam PF13525 Outer membrane lipoprotein 113 226 5.6E-12 T 26-04-2017 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 Pfam PF00970 Oxidoreductase FAD-binding domain 103 197 1.1E-9 T 26-04-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 146 153 6.3E-16 T 26-04-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 207 226 6.3E-16 T 26-04-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 191 200 6.3E-16 T 26-04-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 130 142 6.3E-16 T 26-04-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 298 306 6.3E-16 T 26-04-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 Gene3D G3DSA:2.40.30.10 101 197 8.2E-19 T 26-04-2017 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 SUPERFAMILY SSF54292 1 88 1.84E-21 T 26-04-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 SUPERFAMILY SSF52343 202 332 8.64E-35 T 26-04-2017 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 26-04-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 207 226 7.6E-5 T 26-04-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 298 306 7.6E-5 T 26-04-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 146 153 7.6E-5 T 26-04-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 130 140 7.6E-5 T 26-04-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 SUPERFAMILY SSF63380 99 198 2.15E-17 T 26-04-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 Gene3D G3DSA:3.10.20.30 2 92 2.7E-25 T 26-04-2017 IPR012675 Beta-grasp domain A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 Pfam PF00175 Oxidoreductase NAD-binding domain 209 312 4.6E-20 T 26-04-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 Gene3D G3DSA:3.40.50.80 202 332 3.0E-34 T 26-04-2017 A4V04_RS01140 4f2d228799203b2e8b1422cdc94286f7 333 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 80 6.5E-13 T 26-04-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 Gene3D G3DSA:3.30.230.10 294 465 3.4E-34 T 26-04-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 Pfam PF13541 Subunit ChlI of Mg-chelatase 374 440 5.8E-9 T 26-04-2017 A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 Hamap MF_01498 DNA repair protein RadA [radA]. 24 464 41.741 T 26-04-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 PRINTS PR01874 DNA repair protein radA signature 134 151 7.7E-89 T 26-04-2017 A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 PRINTS PR01874 DNA repair protein radA signature 13 37 7.7E-89 T 26-04-2017 A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 PRINTS PR01874 DNA repair protein radA signature 223 251 7.7E-89 T 26-04-2017 A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 PRINTS PR01874 DNA repair protein radA signature 332 355 7.7E-89 T 26-04-2017 A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 PRINTS PR01874 DNA repair protein radA signature 92 120 7.7E-89 T 26-04-2017 A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 PRINTS PR01874 DNA repair protein radA signature 184 208 7.7E-89 T 26-04-2017 A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 PRINTS PR01874 DNA repair protein radA signature 258 284 7.7E-89 T 26-04-2017 A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 SUPERFAMILY SSF52540 77 303 3.13E-49 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 TIGRFAM TIGR00416 sms: DNA repair protein RadA 6 460 4.6E-186 T 26-04-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 Gene3D G3DSA:3.40.50.300 71 285 6.1E-52 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 SMART SM00382 100 254 1.1E-7 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 SUPERFAMILY SSF54211 313 465 1.82E-40 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 SUPERFAMILY SSF54211 265 279 1.82E-40 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS03780 5a9c66d62e6f55366f26a2d3cbdc7a67 476 Pfam PF13481 AAA domain 92 232 3.7E-14 T 26-04-2017 A4V04_RS06030 0f17afb16b8af24c1b0429ce591a8b4e 81 SMART SM00899 7 79 3.0E-7 T 26-04-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A4V04_RS06030 0f17afb16b8af24c1b0429ce591a8b4e 81 Pfam PF04023 FeoA domain 8 77 4.9E-12 T 26-04-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A4V04_RS06030 0f17afb16b8af24c1b0429ce591a8b4e 81 SUPERFAMILY SSF50037 9 77 2.29E-10 T 26-04-2017 IPR008988 Transcriptional repressor, C-terminal A4V04_RS06910 5344e29288e1a48215a9398dee31ec92 189 Gene3D G3DSA:3.10.50.30 102 178 1.2E-24 T 26-04-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A4V04_RS06910 5344e29288e1a48215a9398dee31ec92 189 SUPERFAMILY SSF46557 25 99 6.67E-25 T 26-04-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A4V04_RS06910 5344e29288e1a48215a9398dee31ec92 189 Hamap MF_00105 Transcription elongation factor GreA [greA]. 24 177 26.058 T 26-04-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 A4V04_RS06910 5344e29288e1a48215a9398dee31ec92 189 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 104 178 1.3E-19 T 26-04-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A4V04_RS06910 5344e29288e1a48215a9398dee31ec92 189 Gene3D G3DSA:1.10.287.180 25 97 2.7E-22 T 26-04-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A4V04_RS06910 5344e29288e1a48215a9398dee31ec92 189 PIRSF PIRSF006092 21 179 3.6E-38 T 26-04-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 A4V04_RS06910 5344e29288e1a48215a9398dee31ec92 189 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 25 179 1.5E-63 T 26-04-2017 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 A4V04_RS06910 5344e29288e1a48215a9398dee31ec92 189 Pfam PF03449 Transcription elongation factor, N-terminal 26 96 6.0E-23 T 26-04-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A4V04_RS06910 5344e29288e1a48215a9398dee31ec92 189 SUPERFAMILY SSF54534 104 178 3.4E-18 T 26-04-2017 A4V04_RS06910 5344e29288e1a48215a9398dee31ec92 189 Hamap MF_00930 Transcription elongation factor GreB [greB]. 23 179 46.318 T 26-04-2017 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 A4V04_RS08760 6f929911f771344a0a218e95950a2265 193 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 16 161 5.5E-31 T 26-04-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A4V04_RS08760 6f929911f771344a0a218e95950a2265 193 Gene3D G3DSA:3.40.50.1000 7 191 4.4E-48 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS08760 6f929911f771344a0a218e95950a2265 193 Pfam PF08645 Polynucleotide kinase 3 phosphatase 36 150 2.8E-9 T 26-04-2017 IPR013954 Polynucleotide kinase 3 phosphatase Reactome: R-HSA-5649702 A4V04_RS08760 6f929911f771344a0a218e95950a2265 193 PIRSF PIRSF004682 9 193 1.4E-50 T 26-04-2017 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 A4V04_RS08760 6f929911f771344a0a218e95950a2265 193 SUPERFAMILY SSF56784 8 191 7.57E-40 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS08760 6f929911f771344a0a218e95950a2265 193 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 17 165 1.4E-29 T 26-04-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 A4V04_RS08760 6f929911f771344a0a218e95950a2265 193 TIGRFAM TIGR00213 GmhB_yaeD: D,D-heptose 1,7-bisphosphate phosphatase 16 169 1.1E-54 T 26-04-2017 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 Gene3D G3DSA:3.30.30.30 72 116 7.3E-7 T 26-04-2017 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 SUPERFAMILY SSF53067 201 381 1.17E-50 T 26-04-2017 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 205 218 - T 26-04-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 PRINTS PR00301 70kDa heat shock protein signature 470 486 4.2E-58 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 PRINTS PR00301 70kDa heat shock protein signature 364 384 4.2E-58 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 PRINTS PR00301 70kDa heat shock protein signature 333 349 4.2E-58 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 PRINTS PR00301 70kDa heat shock protein signature 389 408 4.2E-58 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 PRINTS PR00301 70kDa heat shock protein signature 152 172 4.2E-58 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 PRINTS PR00301 70kDa heat shock protein signature 48 60 4.2E-58 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 PRINTS PR00301 70kDa heat shock protein signature 211 221 4.2E-58 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 PRINTS PR00301 70kDa heat shock protein signature 20 33 4.2E-58 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 SUPERFAMILY SSF100920 388 539 4.05E-50 T 26-04-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 Gene3D G3DSA:3.90.640.10 239 313 1.7E-7 T 26-04-2017 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 Gene3D G3DSA:2.60.34.10 391 532 3.9E-55 T 26-04-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 Gene3D G3DSA:1.20.1270.10 533 617 2.6E-30 T 26-04-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 26-04-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 Gene3D G3DSA:3.30.420.40 20 71 3.5E-53 T 26-04-2017 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 Gene3D G3DSA:3.30.420.40 133 205 3.5E-53 T 26-04-2017 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 336 350 - T 26-04-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 SUPERFAMILY SSF53067 20 197 5.4E-52 T 26-04-2017 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 620 43.064 T 26-04-2017 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 Pfam PF00012 Hsp70 protein 21 603 1.0E-187 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 SUPERFAMILY SSF100934 508 617 2.35E-35 T 26-04-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 617 5.3E-276 T 26-04-2017 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 Gene3D G3DSA:3.30.420.40 318 360 1.0E-30 T 26-04-2017 A4V04_RS00010 12a454f4df47f9102441cf2b83230912 620 Gene3D G3DSA:3.30.420.40 206 238 1.0E-30 T 26-04-2017 A4V04_RS11620 85fced57b40a9767bb96cd4195df6946 413 Pfam PF13103 TonB C terminal 319 405 1.1E-10 T 26-04-2017 IPR006260 TonB, C-terminal GO:0006810 A4V04_RS11620 85fced57b40a9767bb96cd4195df6946 413 SUPERFAMILY SSF74653 319 407 5.1E-7 T 26-04-2017 A4V04_RS11620 85fced57b40a9767bb96cd4195df6946 413 Gene3D G3DSA:3.30.1150.10 300 408 1.6E-11 T 26-04-2017 A4V04_RS11620 85fced57b40a9767bb96cd4195df6946 413 TIGRFAM TIGR02794 tolA_full: protein TolA 20 407 3.2E-27 T 26-04-2017 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 A4V04_RS03425 2b97f17bce7a74666cb62f115902fc07 448 SMART SM00116 225 274 10.0 T 26-04-2017 IPR000644 CBS domain A4V04_RS03425 2b97f17bce7a74666cb62f115902fc07 448 SMART SM00116 289 337 1.2 T 26-04-2017 IPR000644 CBS domain A4V04_RS03425 2b97f17bce7a74666cb62f115902fc07 448 Gene3D G3DSA:3.30.465.10 345 429 2.9E-28 T 26-04-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4V04_RS03425 2b97f17bce7a74666cb62f115902fc07 448 Pfam PF00571 CBS domain 289 336 5.9E-4 T 26-04-2017 IPR000644 CBS domain A4V04_RS03425 2b97f17bce7a74666cb62f115902fc07 448 SUPERFAMILY SSF56176 348 438 2.48E-24 T 26-04-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4V04_RS03425 2b97f17bce7a74666cb62f115902fc07 448 Gene3D G3DSA:3.10.580.10 202 344 2.4E-13 T 26-04-2017 A4V04_RS03425 2b97f17bce7a74666cb62f115902fc07 448 SMART SM01091 350 430 1.3E-29 T 26-04-2017 IPR005170 Transporter-associated domain A4V04_RS03425 2b97f17bce7a74666cb62f115902fc07 448 Pfam PF01595 Domain of unknown function DUF21 10 201 3.3E-39 T 26-04-2017 IPR002550 Domain of unknown function DUF21 A4V04_RS03425 2b97f17bce7a74666cb62f115902fc07 448 SUPERFAMILY SSF54631 204 339 3.18E-21 T 26-04-2017 A4V04_RS03425 2b97f17bce7a74666cb62f115902fc07 448 Pfam PF03471 Transporter associated domain 351 429 5.8E-22 T 26-04-2017 IPR005170 Transporter-associated domain A4V04_RS07590 b474dab690c32d03886a3de203e0c4f7 301 Pfam PF01715 IPP transferase 33 277 1.8E-82 T 26-04-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A4V04_RS07590 b474dab690c32d03886a3de203e0c4f7 301 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 1 284 5.4E-96 T 26-04-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A4V04_RS07590 b474dab690c32d03886a3de203e0c4f7 301 SUPERFAMILY SSF52540 2 151 2.78E-21 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07590 b474dab690c32d03886a3de203e0c4f7 301 Gene3D G3DSA:3.40.50.300 1 165 1.7E-52 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07590 b474dab690c32d03886a3de203e0c4f7 301 Gene3D G3DSA:1.10.287.890 193 275 1.7E-30 T 26-04-2017 A4V04_RS07590 b474dab690c32d03886a3de203e0c4f7 301 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 1 294 27.782 T 26-04-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A4V04_RS07730 ac2ca6e0e783727a1f9e1a35dbf0576b 452 Gene3D G3DSA:3.30.1490.20 130 203 2.4E-29 T 26-04-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4V04_RS07730 ac2ca6e0e783727a1f9e1a35dbf0576b 452 SMART SM00878 336 441 9.6E-62 T 26-04-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4V04_RS07730 ac2ca6e0e783727a1f9e1a35dbf0576b 452 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 1.2E-35 T 26-04-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4V04_RS07730 ac2ca6e0e783727a1f9e1a35dbf0576b 452 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 1.4E-218 T 26-04-2017 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 A4V04_RS07730 ac2ca6e0e783727a1f9e1a35dbf0576b 452 SUPERFAMILY SSF51246 331 446 1.57E-41 T 26-04-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4V04_RS07730 ac2ca6e0e783727a1f9e1a35dbf0576b 452 SUPERFAMILY SSF52440 1 113 4.75E-46 T 26-04-2017 IPR016185 Pre-ATP-grasp domain A4V04_RS07730 ac2ca6e0e783727a1f9e1a35dbf0576b 452 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 26-04-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4V04_RS07730 ac2ca6e0e783727a1f9e1a35dbf0576b 452 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 26-04-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4V04_RS07730 ac2ca6e0e783727a1f9e1a35dbf0576b 452 Gene3D G3DSA:3.40.50.20 1 129 2.7E-50 T 26-04-2017 IPR016185 Pre-ATP-grasp domain A4V04_RS07730 ac2ca6e0e783727a1f9e1a35dbf0576b 452 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 8.8E-43 T 26-04-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4V04_RS07730 ac2ca6e0e783727a1f9e1a35dbf0576b 452 Gene3D G3DSA:3.30.470.20 204 445 1.2E-93 T 26-04-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4V04_RS07730 ac2ca6e0e783727a1f9e1a35dbf0576b 452 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 2.1E-80 T 26-04-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4V04_RS07730 ac2ca6e0e783727a1f9e1a35dbf0576b 452 SUPERFAMILY SSF56059 83 346 2.86E-68 T 26-04-2017 A4V04_RS12965 cedd10c4fef64053f35be52eaad0b929 285 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 23 38 - T 26-04-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4V04_RS12965 cedd10c4fef64053f35be52eaad0b929 285 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 22 276 2.1E-97 T 26-04-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 A4V04_RS12965 cedd10c4fef64053f35be52eaad0b929 285 Gene3D G3DSA:3.20.20.20 19 280 4.4E-105 T 26-04-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4V04_RS12965 cedd10c4fef64053f35be52eaad0b929 285 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 57 70 - T 26-04-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4V04_RS12965 cedd10c4fef64053f35be52eaad0b929 285 Pfam PF00809 Pterin binding enzyme 24 263 9.3E-82 T 26-04-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4V04_RS12965 cedd10c4fef64053f35be52eaad0b929 285 SUPERFAMILY SSF51717 9 280 1.57E-95 T 26-04-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4V04_RS08890 338d6ac2afed5253f4dad437126ecadf 205 ProSitePatterns PS00622 LuxR-type HTH domain signature. 159 186 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08890 338d6ac2afed5253f4dad437126ecadf 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 1.5E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08890 338d6ac2afed5253f4dad437126ecadf 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 1.5E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08890 338d6ac2afed5253f4dad437126ecadf 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 1.5E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08890 338d6ac2afed5253f4dad437126ecadf 205 Gene3D G3DSA:1.10.10.10 148 199 7.4E-22 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS08890 338d6ac2afed5253f4dad437126ecadf 205 SUPERFAMILY SSF52172 9 134 8.97E-32 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS08890 338d6ac2afed5253f4dad437126ecadf 205 SUPERFAMILY SSF46894 135 199 2.45E-19 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS08890 338d6ac2afed5253f4dad437126ecadf 205 Gene3D G3DSA:3.40.50.2300 9 147 8.8E-33 T 26-04-2017 A4V04_RS08890 338d6ac2afed5253f4dad437126ecadf 205 Pfam PF00072 Response regulator receiver domain 9 118 1.1E-26 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS08890 338d6ac2afed5253f4dad437126ecadf 205 SMART SM00448 7 118 9.9E-26 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS08890 338d6ac2afed5253f4dad437126ecadf 205 SMART SM00421 142 199 3.3E-23 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08890 338d6ac2afed5253f4dad437126ecadf 205 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 199 8.1E-18 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS04310 3f9b14269214363d540e80867be5cb7d 125 SUPERFAMILY SSF55298 2 125 1.48E-43 T 26-04-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4V04_RS04310 3f9b14269214363d540e80867be5cb7d 125 Gene3D G3DSA:3.30.1330.40 2 124 4.5E-45 T 26-04-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4V04_RS04310 3f9b14269214363d540e80867be5cb7d 125 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 123 2.2E-44 T 26-04-2017 IPR006056 RidA family A4V04_RS04310 3f9b14269214363d540e80867be5cb7d 125 Pfam PF01042 Endoribonuclease L-PSP 8 123 5.7E-39 T 26-04-2017 IPR006175 YjgF/YER057c/UK114 family A4V04_RS07480 e8f5d5f735d34a2883e1c3a3fef1ed13 271 Gene3D G3DSA:3.20.20.60 9 271 2.6E-110 T 26-04-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4V04_RS07480 e8f5d5f735d34a2883e1c3a3fef1ed13 271 Pfam PF02548 Ketopantoate hydroxymethyltransferase 11 266 4.0E-108 T 26-04-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4V04_RS07480 e8f5d5f735d34a2883e1c3a3fef1ed13 271 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 11 271 1.0E-97 T 26-04-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4V04_RS07480 e8f5d5f735d34a2883e1c3a3fef1ed13 271 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 11 271 40.642 T 26-04-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4V04_RS07480 e8f5d5f735d34a2883e1c3a3fef1ed13 271 PIRSF PIRSF000388 1 271 1.2E-104 T 26-04-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4V04_RS07480 e8f5d5f735d34a2883e1c3a3fef1ed13 271 SUPERFAMILY SSF51621 11 271 3.93E-100 T 26-04-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4V04_RS00190 8c7d52c51ec02537cce3a3bfb260e825 173 SUPERFAMILY SSF54364 7 79 3.14E-28 T 26-04-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4V04_RS00190 8c7d52c51ec02537cce3a3bfb260e825 173 SUPERFAMILY SSF55200 84 173 1.83E-33 T 26-04-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 A4V04_RS00190 8c7d52c51ec02537cce3a3bfb260e825 173 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 3 172 30.084 T 26-04-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4V04_RS00190 8c7d52c51ec02537cce3a3bfb260e825 173 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 9 78 4.0E-30 T 26-04-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4V04_RS00190 8c7d52c51ec02537cce3a3bfb260e825 173 Gene3D G3DSA:3.30.110.10 81 173 1.8E-39 T 26-04-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 A4V04_RS00190 8c7d52c51ec02537cce3a3bfb260e825 173 Gene3D G3DSA:3.10.20.80 4 80 3.2E-35 T 26-04-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4V04_RS00190 8c7d52c51ec02537cce3a3bfb260e825 173 ProSitePatterns PS00938 Initiation factor 3 signature. 60 73 - T 26-04-2017 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 A4V04_RS00190 8c7d52c51ec02537cce3a3bfb260e825 173 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 85 170 4.3E-38 T 26-04-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 A4V04_RS00190 8c7d52c51ec02537cce3a3bfb260e825 173 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 9 172 3.7E-68 T 26-04-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4V04_RS08960 7ce4b3edaadf8b4e7025f4d8ed6bc33c 470 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 26 462 2.6E-120 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS08960 7ce4b3edaadf8b4e7025f4d8ed6bc33c 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 27 46 1.3E-6 T 26-04-2017 A4V04_RS08960 7ce4b3edaadf8b4e7025f4d8ed6bc33c 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 414 436 1.3E-6 T 26-04-2017 A4V04_RS08960 7ce4b3edaadf8b4e7025f4d8ed6bc33c 470 Gene3D G3DSA:3.90.700.10 286 396 1.1E-32 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08960 7ce4b3edaadf8b4e7025f4d8ed6bc33c 470 SUPERFAMILY SSF56425 285 410 5.08E-32 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08960 7ce4b3edaadf8b4e7025f4d8ed6bc33c 470 Gene3D G3DSA:3.50.50.60 406 467 1.9E-94 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08960 7ce4b3edaadf8b4e7025f4d8ed6bc33c 470 Gene3D G3DSA:3.50.50.60 22 266 1.9E-94 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08960 7ce4b3edaadf8b4e7025f4d8ed6bc33c 470 SUPERFAMILY SSF51905 409 467 1.5E-59 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08960 7ce4b3edaadf8b4e7025f4d8ed6bc33c 470 SUPERFAMILY SSF51905 20 285 1.5E-59 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08960 7ce4b3edaadf8b4e7025f4d8ed6bc33c 470 Pfam PF00890 FAD binding domain 26 450 7.6E-80 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 SUPERFAMILY SSF54791 560 644 1.9E-22 T 26-04-2017 IPR004088 K Homology domain, type 1 GO:0003723 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 Pfam PF03725 3' exoribonuclease family, domain 2 465 534 4.2E-5 T 26-04-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 3.4E-12 T 26-04-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 SMART SM00322 557 622 2.3E-11 T 26-04-2017 IPR004087 K Homology domain GO:0003676 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 Gene3D G3DSA:3.30.230.70 3 224 2.2E-85 T 26-04-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 Gene3D G3DSA:3.30.230.70 321 546 2.7E-86 T 26-04-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 SUPERFAMILY SSF55666 145 235 1.16E-29 T 26-04-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 Pfam PF01138 3' exoribonuclease family, domain 1 16 144 1.5E-19 T 26-04-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 Pfam PF01138 3' exoribonuclease family, domain 1 329 461 4.0E-24 T 26-04-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 Gene3D G3DSA:3.30.1370.10 556 623 2.6E-26 T 26-04-2017 IPR004088 K Homology domain, type 1 GO:0003723 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 SUPERFAMILY SSF55666 458 565 1.32E-27 T 26-04-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 Pfam PF00013 KH domain 562 618 3.5E-11 T 26-04-2017 IPR004088 K Homology domain, type 1 GO:0003723 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 SUPERFAMILY SSF50249 625 705 4.76E-22 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 696 0.0 T 26-04-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 SUPERFAMILY SSF54211 302 473 2.99E-47 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 698 30.266 T 26-04-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 Gene3D G3DSA:1.10.10.400 227 320 1.3E-18 T 26-04-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 SUPERFAMILY SSF46915 239 326 6.8E-15 T 26-04-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 Gene3D G3DSA:2.40.50.140 624 699 9.8E-26 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 PIRSF PIRSF005499 1 719 4.1E-298 T 26-04-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 325 3.4E-17 T 26-04-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 SUPERFAMILY SSF54211 2 144 1.47E-51 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 Pfam PF00575 S1 RNA binding domain 624 695 6.8E-18 T 26-04-2017 IPR003029 S1 domain GO:0003676 A4V04_RS03880 3c5cd1e81d96017e37a44e22f229155b 722 SMART SM00316 625 695 5.8E-26 T 26-04-2017 IPR022967 RNA-binding domain, S1 A4V04_RS04950 ddae252fbe38f6eecb74163fbafd4c6f 368 PIRSF PIRSF005962 2 368 4.2E-92 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS04950 ddae252fbe38f6eecb74163fbafd4c6f 368 Pfam PF01546 Peptidase family M20/M25/M40 66 364 7.6E-21 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS04950 ddae252fbe38f6eecb74163fbafd4c6f 368 Pfam PF07687 Peptidase dimerisation domain 167 263 2.5E-6 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS04950 ddae252fbe38f6eecb74163fbafd4c6f 368 Gene3D G3DSA:3.30.70.360 169 273 1.4E-19 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS04950 ddae252fbe38f6eecb74163fbafd4c6f 368 SUPERFAMILY SSF53187 281 365 4.86E-61 T 26-04-2017 A4V04_RS04950 ddae252fbe38f6eecb74163fbafd4c6f 368 SUPERFAMILY SSF53187 7 181 4.86E-61 T 26-04-2017 A4V04_RS04950 ddae252fbe38f6eecb74163fbafd4c6f 368 Gene3D G3DSA:3.40.630.10 7 164 3.2E-67 T 26-04-2017 A4V04_RS04950 ddae252fbe38f6eecb74163fbafd4c6f 368 Gene3D G3DSA:3.40.630.10 278 365 3.2E-67 T 26-04-2017 A4V04_RS04950 ddae252fbe38f6eecb74163fbafd4c6f 368 SUPERFAMILY SSF55031 168 279 9.42E-20 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS04950 ddae252fbe38f6eecb74163fbafd4c6f 368 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 9 353 1.5E-75 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS02685 02f55d443ae7f204a20b4e1d1fb09a6f 453 Pfam PF00583 Acetyltransferase (GNAT) family 352 424 4.7E-9 T 26-04-2017 IPR000182 GNAT domain GO:0008080 A4V04_RS02685 02f55d443ae7f204a20b4e1d1fb09a6f 453 PIRSF PIRSF000423 14 453 2.6E-171 T 26-04-2017 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 A4V04_RS02685 02f55d443ae7f204a20b4e1d1fb09a6f 453 Pfam PF00696 Amino acid kinase family 43 279 1.2E-23 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS02685 02f55d443ae7f204a20b4e1d1fb09a6f 453 SUPERFAMILY SSF55729 311 433 7.43E-20 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS02685 02f55d443ae7f204a20b4e1d1fb09a6f 453 Gene3D G3DSA:3.40.630.30 308 451 3.0E-34 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS02685 02f55d443ae7f204a20b4e1d1fb09a6f 453 SUPERFAMILY SSF53633 22 304 3.01E-63 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS02685 02f55d443ae7f204a20b4e1d1fb09a6f 453 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 25 453 2.4E-164 T 26-04-2017 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 A4V04_RS02685 02f55d443ae7f204a20b4e1d1fb09a6f 453 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 453 178.275 T 26-04-2017 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 A4V04_RS02685 02f55d443ae7f204a20b4e1d1fb09a6f 453 Gene3D G3DSA:3.40.1160.10 41 302 7.1E-62 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS09980 a3ef2b841b10e0f44eaddbbd305645f9 323 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 317 32.739 T 26-04-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A4V04_RS09980 a3ef2b841b10e0f44eaddbbd305645f9 323 Pfam PF02911 Formyl transferase, C-terminal domain 215 314 1.0E-21 T 26-04-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4V04_RS09980 a3ef2b841b10e0f44eaddbbd305645f9 323 SUPERFAMILY SSF53328 1 207 3.66E-53 T 26-04-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4V04_RS09980 a3ef2b841b10e0f44eaddbbd305645f9 323 SUPERFAMILY SSF50486 217 320 2.67E-24 T 26-04-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 A4V04_RS09980 a3ef2b841b10e0f44eaddbbd305645f9 323 Gene3D G3DSA:3.40.50.170 1 216 2.1E-61 T 26-04-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4V04_RS09980 a3ef2b841b10e0f44eaddbbd305645f9 323 Gene3D G3DSA:3.10.25.10 218 322 6.6E-27 T 26-04-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4V04_RS09980 a3ef2b841b10e0f44eaddbbd305645f9 323 Pfam PF00551 Formyl transferase 1 194 4.8E-41 T 26-04-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4V04_RS09980 a3ef2b841b10e0f44eaddbbd305645f9 323 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 319 5.9E-79 T 26-04-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A4V04_RS09980 a3ef2b841b10e0f44eaddbbd305645f9 323 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 147 170 - T 26-04-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4V04_RS12710 9d341c6dbeefec8f79ddb7644189c22b 262 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 6 260 1.9E-84 T 26-04-2017 IPR003453 ABC transport permease subunit MlaE, Proteobacteria A4V04_RS12710 9d341c6dbeefec8f79ddb7644189c22b 262 Pfam PF02405 Permease MlaE 46 257 4.7E-72 T 26-04-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 A4V04_RS02555 396b2e50ec094fa29a8b868984aaa570 331 Gene3D G3DSA:3.30.70.360 230 321 4.6E-20 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS02555 396b2e50ec094fa29a8b868984aaa570 331 SUPERFAMILY SSF53187 4 49 9.43E-47 T 26-04-2017 A4V04_RS02555 396b2e50ec094fa29a8b868984aaa570 331 SUPERFAMILY SSF53187 87 257 9.43E-47 T 26-04-2017 A4V04_RS02555 396b2e50ec094fa29a8b868984aaa570 331 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 9 327 8.6E-69 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS02555 396b2e50ec094fa29a8b868984aaa570 331 SUPERFAMILY SSF55031 220 325 4.78E-18 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS02555 396b2e50ec094fa29a8b868984aaa570 331 PIRSF PIRSF005962 1 331 2.5E-81 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS02555 396b2e50ec094fa29a8b868984aaa570 331 Gene3D G3DSA:3.40.630.10 87 229 7.1E-53 T 26-04-2017 A4V04_RS02555 396b2e50ec094fa29a8b868984aaa570 331 Gene3D G3DSA:3.40.630.10 5 49 7.1E-53 T 26-04-2017 A4V04_RS02555 396b2e50ec094fa29a8b868984aaa570 331 Pfam PF07687 Peptidase dimerisation domain 222 317 1.1E-7 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS02555 396b2e50ec094fa29a8b868984aaa570 331 Pfam PF01546 Peptidase family M20/M25/M40 122 253 2.6E-15 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS09570 97f23f57093bebf68c593cd8876b90d6 170 Gene3D G3DSA:3.40.50.620 1 156 2.6E-51 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS09570 97f23f57093bebf68c593cd8876b90d6 170 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 2 155 2.3E-54 T 26-04-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 A4V04_RS09570 97f23f57093bebf68c593cd8876b90d6 170 Pfam PF01467 Cytidylyltransferase-like 5 132 4.3E-19 T 26-04-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4V04_RS09570 97f23f57093bebf68c593cd8876b90d6 170 SUPERFAMILY SSF52374 1 156 1.2E-41 T 26-04-2017 A4V04_RS09570 97f23f57093bebf68c593cd8876b90d6 170 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 62 5.8E-17 T 26-04-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4V04_RS09570 97f23f57093bebf68c593cd8876b90d6 170 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 1 157 33.084 T 26-04-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 A4V04_RS09570 97f23f57093bebf68c593cd8876b90d6 170 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 111 133 1.0E-44 T 26-04-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 A4V04_RS09570 97f23f57093bebf68c593cd8876b90d6 170 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 84 100 1.0E-44 T 26-04-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 A4V04_RS09570 97f23f57093bebf68c593cd8876b90d6 170 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 1 19 1.0E-44 T 26-04-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 A4V04_RS09570 97f23f57093bebf68c593cd8876b90d6 170 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 19 40 1.0E-44 T 26-04-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 A4V04_RS09570 97f23f57093bebf68c593cd8876b90d6 170 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 48 72 1.0E-44 T 26-04-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 A4V04_RS09570 97f23f57093bebf68c593cd8876b90d6 170 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 10 72 1.0E-4 T 26-04-2017 A4V04_RS02530 985eab800c6cbbd1a51270b7d6616c46 462 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 61 451 3.5E-95 T 26-04-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A4V04_RS02530 985eab800c6cbbd1a51270b7d6616c46 462 Pfam PF03606 C4-dicarboxylate anaerobic carrier 3 459 4.7E-70 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS05595 1d424e9da0366dd631c24b4c1caa5ddf 361 SUPERFAMILY SSF53335 10 349 3.95E-50 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS05595 1d424e9da0366dd631c24b4c1caa5ddf 361 Gene3D G3DSA:3.40.50.150 42 265 7.0E-15 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS05595 1d424e9da0366dd631c24b4c1caa5ddf 361 Pfam PF02384 N-6 DNA Methylase 40 170 5.2E-11 T 26-04-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A4V04_RS05595 1d424e9da0366dd631c24b4c1caa5ddf 361 Pfam PF02384 N-6 DNA Methylase 184 286 8.4E-6 T 26-04-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A4V04_RS08970 38bbfb30345424991249afd8572bb324 205 SMART SM00421 139 196 3.8E-19 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08970 38bbfb30345424991249afd8572bb324 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 4.4E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08970 38bbfb30345424991249afd8572bb324 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 4.4E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08970 38bbfb30345424991249afd8572bb324 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 4.4E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08970 38bbfb30345424991249afd8572bb324 205 SUPERFAMILY SSF52172 6 121 8.4E-28 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS08970 38bbfb30345424991249afd8572bb324 205 SUPERFAMILY SSF46894 135 202 4.42E-18 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS08970 38bbfb30345424991249afd8572bb324 205 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 194 1.0E-18 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08970 38bbfb30345424991249afd8572bb324 205 Gene3D G3DSA:3.40.50.2300 5 142 3.2E-28 T 26-04-2017 A4V04_RS08970 38bbfb30345424991249afd8572bb324 205 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08970 38bbfb30345424991249afd8572bb324 205 Gene3D G3DSA:1.10.10.10 143 198 1.1E-20 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS08970 38bbfb30345424991249afd8572bb324 205 Pfam PF00072 Response regulator receiver domain 6 116 9.1E-23 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS08970 38bbfb30345424991249afd8572bb324 205 SMART SM00448 4 115 5.7E-22 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS01695 d30f0eeae03750ca8dde6fd2f8f36dcc 183 Pfam PF02613 Nitrate reductase delta subunit 31 148 3.2E-11 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS01695 d30f0eeae03750ca8dde6fd2f8f36dcc 183 SUPERFAMILY SSF89155 15 177 5.89E-20 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS01695 d30f0eeae03750ca8dde6fd2f8f36dcc 183 Gene3D G3DSA:1.10.3480.10 31 177 3.2E-14 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS12575 2fd8ba11c1458f99956d4e363471ee3f 114 Gene3D G3DSA:3.30.428.10 2 109 1.1E-40 T 26-04-2017 IPR011146 HIT-like domain GO:0003824 A4V04_RS12575 2fd8ba11c1458f99956d4e363471ee3f 114 SUPERFAMILY SSF54197 3 109 3.4E-37 T 26-04-2017 IPR011146 HIT-like domain GO:0003824 A4V04_RS12575 2fd8ba11c1458f99956d4e363471ee3f 114 ProSitePatterns PS00892 HIT domain signature. 88 106 - T 26-04-2017 IPR019808 Histidine triad, conserved site A4V04_RS12575 2fd8ba11c1458f99956d4e363471ee3f 114 PRINTS PR00332 Histidine triad family signature 28 46 2.0E-19 T 26-04-2017 IPR001310 Histidine triad (HIT) protein A4V04_RS12575 2fd8ba11c1458f99956d4e363471ee3f 114 PRINTS PR00332 Histidine triad family signature 7 23 2.0E-19 T 26-04-2017 IPR001310 Histidine triad (HIT) protein A4V04_RS12575 2fd8ba11c1458f99956d4e363471ee3f 114 PRINTS PR00332 Histidine triad family signature 95 105 2.0E-19 T 26-04-2017 IPR001310 Histidine triad (HIT) protein A4V04_RS12575 2fd8ba11c1458f99956d4e363471ee3f 114 Pfam PF01230 HIT domain 14 107 6.1E-26 T 26-04-2017 IPR001310 Histidine triad (HIT) protein A4V04_RS10490 d8869686095e61376e698ef667a88d4b 146 SUPERFAMILY SSF54211 11 109 7.59E-11 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS10490 d8869686095e61376e698ef667a88d4b 146 Gene3D G3DSA:3.30.230.10 9 123 2.8E-15 T 26-04-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4V04_RS10490 d8869686095e61376e698ef667a88d4b 146 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 9 137 11.642 T 26-04-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A4V04_RS10490 d8869686095e61376e698ef667a88d4b 146 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 50 88 2.0E-4 T 26-04-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A4V04_RS10490 d8869686095e61376e698ef667a88d4b 146 Pfam PF00825 Ribonuclease P 12 124 1.2E-12 T 26-04-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 Gene3D G3DSA:3.40.50.2300 490 631 4.0E-20 T 26-04-2017 A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 SUPERFAMILY SSF52172 491 628 8.11E-18 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 SUPERFAMILY SSF47384 239 315 2.35E-10 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 4.0E-11 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 410 4.0E-11 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 4.0E-11 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 424 4.0E-11 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 SUPERFAMILY SSF55874 304 468 5.24E-36 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 Gene3D G3DSA:1.10.287.130 246 311 7.1E-8 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 SMART SM00448 493 623 4.2E-10 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 SMART SM00388 251 315 6.7E-10 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 Gene3D G3DSA:3.30.565.10 317 470 3.3E-37 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 314 2.2E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 SMART SM00387 359 470 7.2E-30 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 360 469 3.0E-18 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05755 44a6f1d234d84aeb47a21f43478d0045 632 Pfam PF00072 Response regulator receiver domain 495 586 7.1E-11 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS01975 3e7de490aafa69477c4006d29586aeaf 176 SUPERFAMILY SSF53850 43 149 2.04E-5 T 26-04-2017 A4V04_RS01975 3e7de490aafa69477c4006d29586aeaf 176 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 41 137 2.3E-6 T 26-04-2017 A4V04_RS07775 a7fee4a9e2d19645ee05257b21caa079 891 Gene3D G3DSA:1.25.50.10 557 887 1.3E-89 T 26-04-2017 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal A4V04_RS07775 a7fee4a9e2d19645ee05257b21caa079 891 SUPERFAMILY SSF63737 2 195 1.22E-39 T 26-04-2017 A4V04_RS07775 a7fee4a9e2d19645ee05257b21caa079 891 SUPERFAMILY SSF55486 213 456 2.78E-67 T 26-04-2017 A4V04_RS07775 a7fee4a9e2d19645ee05257b21caa079 891 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 12 886 0.0 T 26-04-2017 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 A4V04_RS07775 a7fee4a9e2d19645ee05257b21caa079 891 Pfam PF01433 Peptidase family M1 50 390 2.3E-61 T 26-04-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4V04_RS07775 a7fee4a9e2d19645ee05257b21caa079 891 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 178 193 2.4E-7 T 26-04-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4V04_RS07775 a7fee4a9e2d19645ee05257b21caa079 891 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 315 327 2.4E-7 T 26-04-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4V04_RS07775 a7fee4a9e2d19645ee05257b21caa079 891 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 296 311 2.4E-7 T 26-04-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4V04_RS07775 a7fee4a9e2d19645ee05257b21caa079 891 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 260 270 2.4E-7 T 26-04-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4V04_RS07775 a7fee4a9e2d19645ee05257b21caa079 891 Pfam PF11940 Domain of unknown function (DUF3458) 464 845 5.9E-105 T 26-04-2017 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal A4V04_RS07775 a7fee4a9e2d19645ee05257b21caa079 891 Gene3D G3DSA:1.10.390.10 310 457 8.7E-31 T 26-04-2017 A4V04_RS09030 8333818b6925e4c37c0286a60b9abdf0 310 Pfam PF02603 HPr Serine kinase N terminus 12 127 6.3E-14 T 26-04-2017 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 A4V04_RS09030 8333818b6925e4c37c0286a60b9abdf0 310 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 7 305 1.9E-90 T 26-04-2017 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 A4V04_RS09030 8333818b6925e4c37c0286a60b9abdf0 310 Gene3D G3DSA:3.40.1390.20 10 129 9.3E-17 T 26-04-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A4V04_RS09030 8333818b6925e4c37c0286a60b9abdf0 310 SUPERFAMILY SSF53795 138 301 1.74E-30 T 26-04-2017 A4V04_RS09030 8333818b6925e4c37c0286a60b9abdf0 310 SUPERFAMILY SSF75138 11 128 1.31E-13 T 26-04-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A4V04_RS09030 8333818b6925e4c37c0286a60b9abdf0 310 Gene3D G3DSA:3.40.50.300 137 309 2.7E-60 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09030 8333818b6925e4c37c0286a60b9abdf0 310 Pfam PF07475 HPr Serine kinase C-terminal domain 135 301 2.0E-60 T 26-04-2017 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 Gene3D G3DSA:3.50.30.20 12 150 1.1E-59 T 26-04-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 279 295 4.8E-38 T 26-04-2017 A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 321 332 4.8E-38 T 26-04-2017 A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 296 313 4.8E-38 T 26-04-2017 A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 209 223 4.8E-38 T 26-04-2017 A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 248 262 4.8E-38 T 26-04-2017 A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 Pfam PF00117 Glutamine amidotransferase class-I 213 387 5.8E-47 T 26-04-2017 IPR017926 Glutamine amidotransferase A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 SMART SM01097 11 141 1.1E-86 T 26-04-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 SUPERFAMILY SSF52317 166 392 1.63E-61 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 SUPERFAMILY SSF52021 12 147 7.45E-56 T 26-04-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 13 390 5.7E-142 T 26-04-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 Gene3D G3DSA:3.40.50.880 166 392 2.0E-79 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 11 393 47.6 T 26-04-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 13 140 4.7E-52 T 26-04-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 PRINTS PR00096 Glutamine amidotransferase superfamily signature 364 377 2.0E-10 T 26-04-2017 A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 PRINTS PR00096 Glutamine amidotransferase superfamily signature 251 260 2.0E-10 T 26-04-2017 A4V04_RS06955 77571edebac8190f9c90ce4d01bdc780 394 PRINTS PR00096 Glutamine amidotransferase superfamily signature 279 290 2.0E-10 T 26-04-2017 A4V04_RS08360 2820f4bba0bfcac98acd32537d4afdbe 319 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 75 2.5E-5 T 26-04-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A4V04_RS08360 2820f4bba0bfcac98acd32537d4afdbe 319 SUPERFAMILY SSF161098 99 301 1.57E-26 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS08360 2820f4bba0bfcac98acd32537d4afdbe 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 315 5.1E-27 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS08360 2820f4bba0bfcac98acd32537d4afdbe 319 Gene3D G3DSA:1.10.3720.10 95 313 1.7E-28 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS06680 09cbbecf783880890aa1ca91de488e6e 222 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 53 180 5.9E-15 T 26-04-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4V04_RS06680 09cbbecf783880890aa1ca91de488e6e 222 SUPERFAMILY SSF48150 40 215 5.06E-41 T 26-04-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4V04_RS06680 09cbbecf783880890aa1ca91de488e6e 222 SMART SM00478 57 213 9.5E-19 T 26-04-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4V04_RS06680 09cbbecf783880890aa1ca91de488e6e 222 Gene3D G3DSA:1.10.1670.10 158 217 8.7E-12 T 26-04-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A4V04_RS06680 09cbbecf783880890aa1ca91de488e6e 222 Gene3D G3DSA:1.10.340.30 48 156 1.1E-30 T 26-04-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4V04_RS11300 2d51e474c2bb8005f2d84d1f94e2ead9 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 35.188 T 26-04-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4V04_RS11300 2d51e474c2bb8005f2d84d1f94e2ead9 177 Gene3D G3DSA:3.90.930.12 84 177 1.2E-39 T 26-04-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11300 2d51e474c2bb8005f2d84d1f94e2ead9 177 Gene3D G3DSA:3.90.930.12 2 82 9.9E-24 T 26-04-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11300 2d51e474c2bb8005f2d84d1f94e2ead9 177 SUPERFAMILY SSF56053 83 177 7.77E-36 T 26-04-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11300 2d51e474c2bb8005f2d84d1f94e2ead9 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 26-04-2017 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11300 2d51e474c2bb8005f2d84d1f94e2ead9 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 3.3E-31 T 26-04-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4V04_RS11300 2d51e474c2bb8005f2d84d1f94e2ead9 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 3.3E-31 T 26-04-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4V04_RS11300 2d51e474c2bb8005f2d84d1f94e2ead9 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 3.3E-31 T 26-04-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4V04_RS11300 2d51e474c2bb8005f2d84d1f94e2ead9 177 SUPERFAMILY SSF56053 1 82 2.4E-21 T 26-04-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11300 2d51e474c2bb8005f2d84d1f94e2ead9 177 PIRSF PIRSF002162 1 177 2.2E-47 T 26-04-2017 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11300 2d51e474c2bb8005f2d84d1f94e2ead9 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 4.3E-71 T 26-04-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4V04_RS11300 2d51e474c2bb8005f2d84d1f94e2ead9 177 Pfam PF00347 Ribosomal protein L6 13 82 9.9E-14 T 26-04-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11300 2d51e474c2bb8005f2d84d1f94e2ead9 177 Pfam PF00347 Ribosomal protein L6 90 164 1.8E-21 T 26-04-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS01605 a0508e54fd3b438307f38f5085c687ba 376 Pfam PF03466 LysR substrate binding domain 135 330 3.0E-17 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS01605 a0508e54fd3b438307f38f5085c687ba 376 SUPERFAMILY SSF53850 132 339 5.07E-21 T 26-04-2017 A4V04_RS01605 a0508e54fd3b438307f38f5085c687ba 376 Gene3D G3DSA:1.10.10.10 50 129 7.6E-20 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01605 a0508e54fd3b438307f38f5085c687ba 376 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 51 106 5.0E-17 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS01605 a0508e54fd3b438307f38f5085c687ba 376 Gene3D G3DSA:3.40.190.10 136 261 2.6E-10 T 26-04-2017 A4V04_RS01605 a0508e54fd3b438307f38f5085c687ba 376 Gene3D G3DSA:3.40.190.10 262 310 7.1E-5 T 26-04-2017 A4V04_RS01605 a0508e54fd3b438307f38f5085c687ba 376 SUPERFAMILY SSF46785 48 153 3.69E-18 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07690 4763adbb32f08afe821805622786fb1c 485 Pfam PF01769 Divalent cation transporter 351 476 3.4E-24 T 26-04-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A4V04_RS07690 4763adbb32f08afe821805622786fb1c 485 Gene3D G3DSA:1.25.60.10 56 159 2.2E-22 T 26-04-2017 A4V04_RS07690 4763adbb32f08afe821805622786fb1c 485 Gene3D G3DSA:3.10.580.10 160 291 5.5E-17 T 26-04-2017 A4V04_RS07690 4763adbb32f08afe821805622786fb1c 485 SUPERFAMILY SSF161093 307 483 2.35E-47 T 26-04-2017 A4V04_RS07690 4763adbb32f08afe821805622786fb1c 485 Pfam PF03448 MgtE intracellular N domain 64 165 1.8E-24 T 26-04-2017 IPR006668 Magnesium transporter, MgtE intracellular domain A4V04_RS07690 4763adbb32f08afe821805622786fb1c 485 TIGRFAM TIGR00400 mgtE: magnesium transporter 56 483 1.9E-80 T 26-04-2017 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 A4V04_RS07690 4763adbb32f08afe821805622786fb1c 485 SMART SM00924 64 167 2.1E-35 T 26-04-2017 IPR006668 Magnesium transporter, MgtE intracellular domain A4V04_RS07690 4763adbb32f08afe821805622786fb1c 485 Gene3D G3DSA:1.10.357.20 308 484 7.9E-50 T 26-04-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A4V04_RS07690 4763adbb32f08afe821805622786fb1c 485 SUPERFAMILY SSF54631 167 302 3.79E-25 T 26-04-2017 A4V04_RS07690 4763adbb32f08afe821805622786fb1c 485 SUPERFAMILY SSF158791 57 164 2.49E-26 T 26-04-2017 A4V04_RS07690 4763adbb32f08afe821805622786fb1c 485 SMART SM00116 174 227 67.0 T 26-04-2017 IPR000644 CBS domain A4V04_RS07690 4763adbb32f08afe821805622786fb1c 485 SMART SM00116 238 286 8.3E-6 T 26-04-2017 IPR000644 CBS domain A4V04_RS07690 4763adbb32f08afe821805622786fb1c 485 Pfam PF00571 CBS domain 231 284 2.5E-6 T 26-04-2017 IPR000644 CBS domain A4V04_RS10830 44ec5116a34b8da1e6328341ae8baf83 284 Gene3D G3DSA:1.10.12.10 223 272 6.3E-29 T 26-04-2017 IPR014748 Crontonase, C-terminal A4V04_RS10830 44ec5116a34b8da1e6328341ae8baf83 284 SUPERFAMILY SSF52096 13 280 4.29E-81 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS10830 44ec5116a34b8da1e6328341ae8baf83 284 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 16 283 55.193 T 26-04-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 A4V04_RS10830 44ec5116a34b8da1e6328341ae8baf83 284 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 122 142 - T 26-04-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A4V04_RS10830 44ec5116a34b8da1e6328341ae8baf83 284 TIGRFAM TIGR01929 menB: naphthoate synthase 22 280 3.9E-140 T 26-04-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 A4V04_RS10830 44ec5116a34b8da1e6328341ae8baf83 284 Gene3D G3DSA:3.90.226.10 22 221 6.8E-72 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS10830 44ec5116a34b8da1e6328341ae8baf83 284 Pfam PF00378 Enoyl-CoA hydratase/isomerase 31 278 6.9E-80 T 26-04-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A4V04_RS02635 3c4b72bf117fc05f6f4f57833884e149 1193 SUPERFAMILY SSF103515 883 1193 1.44E-27 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02635 3c4b72bf117fc05f6f4f57833884e149 1193 Gene3D G3DSA:2.40.128.130 863 1193 4.6E-54 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02635 3c4b72bf117fc05f6f4f57833884e149 1193 SMART SM00869 905 1180 2.0E-14 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02635 3c4b72bf117fc05f6f4f57833884e149 1193 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 964 1193 6.1E-25 T 26-04-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 A4V04_RS02635 3c4b72bf117fc05f6f4f57833884e149 1193 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 857 939 1.3E-10 T 26-04-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 A4V04_RS02635 3c4b72bf117fc05f6f4f57833884e149 1193 Pfam PF03797 Autotransporter beta-domain 906 1160 7.1E-26 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS07675 99de58d703d27a3210331bb34733c78d 320 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 283 2.0E-52 T 26-04-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4V04_RS07675 99de58d703d27a3210331bb34733c78d 320 SUPERFAMILY SSF52283 4 134 7.18E-22 T 26-04-2017 A4V04_RS07675 99de58d703d27a3210331bb34733c78d 320 Gene3D G3DSA:3.40.50.720 1 110 1.4E-24 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS07675 99de58d703d27a3210331bb34733c78d 320 SUPERFAMILY SSF51735 105 284 1.37E-51 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS07675 99de58d703d27a3210331bb34733c78d 320 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 26-04-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4V04_RS07675 99de58d703d27a3210331bb34733c78d 320 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 30 308 3.0E-21 T 26-04-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A4V04_RS07675 99de58d703d27a3210331bb34733c78d 320 Gene3D G3DSA:3.40.50.720 111 284 4.3E-60 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS10515 3e85141a16f73f31395a978fc05fb5e3 550 Gene3D G3DSA:1.20.200.10 230 546 2.7E-61 T 26-04-2017 A4V04_RS10515 3e85141a16f73f31395a978fc05fb5e3 550 Pfam PF00221 Aromatic amino acid lyase 31 522 2.4E-99 T 26-04-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 A4V04_RS10515 3e85141a16f73f31395a978fc05fb5e3 550 Gene3D G3DSA:1.10.275.10 24 223 2.7E-38 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS10515 3e85141a16f73f31395a978fc05fb5e3 550 SUPERFAMILY SSF48557 23 547 3.92E-109 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS09900 2341b27ac7a6401bcc383c6fae95c603 223 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 11 195 1.8E-53 T 26-04-2017 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4V04_RS09900 2341b27ac7a6401bcc383c6fae95c603 223 SUPERFAMILY SSF53271 3 200 1.3E-40 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS09900 2341b27ac7a6401bcc383c6fae95c603 223 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 223 32.191 T 26-04-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4V04_RS09900 2341b27ac7a6401bcc383c6fae95c603 223 Pfam PF00156 Phosphoribosyl transferase domain 55 161 1.8E-11 T 26-04-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4V04_RS09900 2341b27ac7a6401bcc383c6fae95c603 223 Gene3D G3DSA:3.40.50.2020 7 223 2.4E-72 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS11375 d335f0c4460ec0c8657bd8080fb15d76 734 Gene3D G3DSA:2.40.40.20 606 732 1.4E-27 T 26-04-2017 A4V04_RS11375 d335f0c4460ec0c8657bd8080fb15d76 734 Gene3D G3DSA:2.20.25.90 41 98 2.7E-8 T 26-04-2017 A4V04_RS11375 d335f0c4460ec0c8657bd8080fb15d76 734 SUPERFAMILY SSF53706 45 620 1.31E-108 T 26-04-2017 A4V04_RS11375 d335f0c4460ec0c8657bd8080fb15d76 734 Pfam PF01568 Molydopterin dinucleotide binding domain 624 723 4.3E-17 T 26-04-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4V04_RS11375 d335f0c4460ec0c8657bd8080fb15d76 734 Gene3D G3DSA:3.40.228.10 211 370 7.1E-52 T 26-04-2017 A4V04_RS11375 d335f0c4460ec0c8657bd8080fb15d76 734 SUPERFAMILY SSF50692 582 732 6.78E-28 T 26-04-2017 IPR009010 Aspartate decarboxylase-like domain A4V04_RS11375 d335f0c4460ec0c8657bd8080fb15d76 734 Gene3D G3DSA:3.40.50.740 99 210 5.1E-31 T 26-04-2017 A4V04_RS11375 d335f0c4460ec0c8657bd8080fb15d76 734 Gene3D G3DSA:3.40.50.740 411 521 5.1E-31 T 26-04-2017 A4V04_RS11375 d335f0c4460ec0c8657bd8080fb15d76 734 Pfam PF00384 Molybdopterin oxidoreductase 98 517 2.7E-42 T 26-04-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS11375 d335f0c4460ec0c8657bd8080fb15d76 734 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 659 686 - T 26-04-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A4V04_RS01460 574deca78f0470ad2647008ae2178a0e 213 Gene3D G3DSA:3.30.1330.60 80 207 4.7E-35 T 26-04-2017 IPR006665 OmpA-like domain A4V04_RS01460 574deca78f0470ad2647008ae2178a0e 213 SUPERFAMILY SSF103088 84 206 3.92E-30 T 26-04-2017 IPR006665 OmpA-like domain A4V04_RS01460 574deca78f0470ad2647008ae2178a0e 213 Pfam PF00691 OmpA family 92 183 1.9E-19 T 26-04-2017 IPR006665 OmpA-like domain A4V04_RS01460 574deca78f0470ad2647008ae2178a0e 213 PRINTS PR01021 OMPA domain signature 138 154 3.5E-17 T 26-04-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A4V04_RS01460 574deca78f0470ad2647008ae2178a0e 213 PRINTS PR01021 OMPA domain signature 123 138 3.5E-17 T 26-04-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A4V04_RS01460 574deca78f0470ad2647008ae2178a0e 213 PRINTS PR01021 OMPA domain signature 93 115 3.5E-17 T 26-04-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A4V04_RS01635 f2c8b15d0faeb460e8ef100126e90c41 436 PIRSF PIRSF004539 1 436 4.8E-142 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS01635 f2c8b15d0faeb460e8ef100126e90c41 436 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 6 368 2.1E-128 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS01635 f2c8b15d0faeb460e8ef100126e90c41 436 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 6 436 3.9E-127 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS00735 66a667bd30bd9d72d15140cc6bfe7387 244 Gene3D G3DSA:1.10.10.10 165 236 8.0E-26 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS00735 66a667bd30bd9d72d15140cc6bfe7387 244 SUPERFAMILY SSF51206 17 155 2.23E-25 T 26-04-2017 IPR018490 Cyclic nucleotide-binding-like A4V04_RS00735 66a667bd30bd9d72d15140cc6bfe7387 244 Pfam PF13545 Crp-like helix-turn-helix domain 162 236 7.2E-18 T 26-04-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4V04_RS00735 66a667bd30bd9d72d15140cc6bfe7387 244 Pfam PF00027 Cyclic nucleotide-binding domain 47 130 4.3E-14 T 26-04-2017 IPR000595 Cyclic nucleotide-binding domain A4V04_RS00735 66a667bd30bd9d72d15140cc6bfe7387 244 SUPERFAMILY SSF46785 160 237 2.78E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS00735 66a667bd30bd9d72d15140cc6bfe7387 244 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 187 203 6.7E-10 T 26-04-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4V04_RS00735 66a667bd30bd9d72d15140cc6bfe7387 244 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 203 218 6.7E-10 T 26-04-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4V04_RS00735 66a667bd30bd9d72d15140cc6bfe7387 244 SMART SM00100 24 145 0.0014 T 26-04-2017 IPR000595 Cyclic nucleotide-binding domain A4V04_RS00735 66a667bd30bd9d72d15140cc6bfe7387 244 SMART SM00419 181 229 3.3E-13 T 26-04-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4V04_RS00735 66a667bd30bd9d72d15140cc6bfe7387 244 Gene3D G3DSA:2.60.120.10 14 164 3.2E-23 T 26-04-2017 IPR014710 RmlC-like jelly roll fold A4V04_RS01925 83059118f55baedd75e183c6d88c980d 348 Gene3D G3DSA:3.90.550.10 12 245 3.2E-37 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS01925 83059118f55baedd75e183c6d88c980d 348 Pfam PF00535 Glycosyl transferase family 2 13 127 2.6E-21 T 26-04-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4V04_RS01925 83059118f55baedd75e183c6d88c980d 348 SUPERFAMILY SSF53448 12 227 3.13E-38 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS05165 8232c813214a36e765eafb6ae03aa6ad 521 Pfam PF00589 Phage integrase family 311 504 1.4E-15 T 26-04-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS05165 8232c813214a36e765eafb6ae03aa6ad 521 SUPERFAMILY SSF56349 164 216 9.71E-29 T 26-04-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4V04_RS05165 8232c813214a36e765eafb6ae03aa6ad 521 SUPERFAMILY SSF56349 255 513 9.71E-29 T 26-04-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4V04_RS05165 8232c813214a36e765eafb6ae03aa6ad 521 Gene3D G3DSA:1.10.443.10 309 516 7.0E-24 T 26-04-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS05165 8232c813214a36e765eafb6ae03aa6ad 521 Gene3D G3DSA:1.10.150.130 160 217 2.0E-12 T 26-04-2017 IPR023109 Integrase/recombinase, N-terminal A4V04_RS05165 8232c813214a36e765eafb6ae03aa6ad 521 Gene3D G3DSA:1.10.150.130 255 289 2.0E-12 T 26-04-2017 IPR023109 Integrase/recombinase, N-terminal A4V04_RS06740 d8c31469efbd65224de16f0f70dc37f2 465 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 5 114 7.7E-23 T 26-04-2017 IPR017560 Cytochrome c-type biogenesis protein CcmI A4V04_RS06740 d8c31469efbd65224de16f0f70dc37f2 465 Gene3D G3DSA:1.25.40.10 209 287 2.6E-21 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS06740 d8c31469efbd65224de16f0f70dc37f2 465 SUPERFAMILY SSF48452 152 265 1.34E-16 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS06740 d8c31469efbd65224de16f0f70dc37f2 465 Gene3D G3DSA:1.25.40.10 146 208 1.1E-8 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS09000 011edee4fa96db870385984052ea845c 176 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 10 162 4.8E-43 T 26-04-2017 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A4V04_RS09000 011edee4fa96db870385984052ea845c 176 SUPERFAMILY SSF56784 8 170 8.53E-39 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS09000 011edee4fa96db870385984052ea845c 176 PIRSF PIRSF006118 1 172 6.0E-60 T 26-04-2017 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A4V04_RS09000 011edee4fa96db870385984052ea845c 176 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 11 127 8.5E-13 T 26-04-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A4V04_RS09000 011edee4fa96db870385984052ea845c 176 Pfam PF08282 haloacid dehalogenase-like hydrolase 79 143 5.5E-5 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS09000 011edee4fa96db870385984052ea845c 176 Gene3D G3DSA:3.40.50.1000 2 168 9.2E-40 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS01355 8b69b8da700f2a9c0b48b20baa587411 399 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 15 380 1.2E-97 T 26-04-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4V04_RS01355 8b69b8da700f2a9c0b48b20baa587411 399 SUPERFAMILY SSF52413 313 376 2.49E-13 T 26-04-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4V04_RS01355 8b69b8da700f2a9c0b48b20baa587411 399 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 209 297 2.4E-20 T 26-04-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4V04_RS01355 8b69b8da700f2a9c0b48b20baa587411 399 SUPERFAMILY SSF48179 208 297 1.33E-19 T 26-04-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4V04_RS01355 8b69b8da700f2a9c0b48b20baa587411 399 Gene3D G3DSA:3.40.50.720 14 229 2.3E-48 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01355 8b69b8da700f2a9c0b48b20baa587411 399 PIRSF PIRSF000124 14 389 1.7E-43 T 26-04-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4V04_RS01355 8b69b8da700f2a9c0b48b20baa587411 399 SMART SM00984 321 398 0.0026 T 26-04-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4V04_RS01355 8b69b8da700f2a9c0b48b20baa587411 399 Gene3D G3DSA:3.40.50.720 240 375 5.3E-27 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01355 8b69b8da700f2a9c0b48b20baa587411 399 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 15 188 9.1E-31 T 26-04-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4V04_RS01355 8b69b8da700f2a9c0b48b20baa587411 399 SUPERFAMILY SSF51735 15 201 9.87E-39 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01355 8b69b8da700f2a9c0b48b20baa587411 399 PIRSF PIRSF500136 5 392 4.8E-115 T 26-04-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A4V04_RS01355 8b69b8da700f2a9c0b48b20baa587411 399 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 373 5.0E-9 T 26-04-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4V04_RS08975 317cbfb7b2068ab602374087d5d51e93 599 SUPERFAMILY SSF47384 368 443 2.35E-8 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS08975 317cbfb7b2068ab602374087d5d51e93 599 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 485 585 1.4E-8 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS08975 317cbfb7b2068ab602374087d5d51e93 599 SMART SM00387 482 592 1.3E-10 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS08975 317cbfb7b2068ab602374087d5d51e93 599 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 35 269 7.3E-28 T 26-04-2017 A4V04_RS08975 317cbfb7b2068ab602374087d5d51e93 599 SUPERFAMILY SSF55874 429 586 7.41E-22 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS08975 317cbfb7b2068ab602374087d5d51e93 599 Gene3D G3DSA:3.30.565.10 428 589 7.1E-21 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS08975 317cbfb7b2068ab602374087d5d51e93 599 SMART SM00388 372 442 6.5E-6 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS08975 317cbfb7b2068ab602374087d5d51e93 599 Gene3D G3DSA:1.10.287.130 375 427 6.7E-4 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS08975 317cbfb7b2068ab602374087d5d51e93 599 SUPERFAMILY SSF53850 47 275 1.38E-17 T 26-04-2017 A4V04_RS08975 317cbfb7b2068ab602374087d5d51e93 599 Gene3D G3DSA:3.40.190.10 125 229 9.3E-6 T 26-04-2017 A4V04_RS10915 ce0754ee5019029628e87bc209d6154c 593 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 539 561 4.2E-6 T 26-04-2017 A4V04_RS10915 ce0754ee5019029628e87bc209d6154c 593 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 153 4.2E-6 T 26-04-2017 A4V04_RS10915 ce0754ee5019029628e87bc209d6154c 593 SUPERFAMILY SSF56425 379 535 5.93E-29 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10915 ce0754ee5019029628e87bc209d6154c 593 Pfam PF04205 FMN-binding domain 35 106 1.5E-9 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS10915 ce0754ee5019029628e87bc209d6154c 593 SMART SM00900 35 109 7.7E-11 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS10915 ce0754ee5019029628e87bc209d6154c 593 SUPERFAMILY SSF51905 121 390 2.18E-54 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10915 ce0754ee5019029628e87bc209d6154c 593 SUPERFAMILY SSF51905 534 591 2.18E-54 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10915 ce0754ee5019029628e87bc209d6154c 593 Gene3D G3DSA:3.90.700.10 379 526 7.9E-24 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10915 ce0754ee5019029628e87bc209d6154c 593 Gene3D G3DSA:3.50.50.60 117 373 9.2E-93 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10915 ce0754ee5019029628e87bc209d6154c 593 Gene3D G3DSA:3.50.50.60 531 591 9.2E-93 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10915 ce0754ee5019029628e87bc209d6154c 593 Pfam PF00890 FAD binding domain 134 574 4.9E-83 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10915 ce0754ee5019029628e87bc209d6154c 593 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 133 587 3.2E-117 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS04465 2e7f1fbbae0d1f5b197571af9be90d26 218 SUPERFAMILY SSF56784 6 216 8.0E-49 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS04465 2e7f1fbbae0d1f5b197571af9be90d26 218 Gene3D G3DSA:3.40.50.1000 76 217 1.2E-34 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS04465 2e7f1fbbae0d1f5b197571af9be90d26 218 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 102 181 2.4E-9 T 26-04-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4V04_RS04465 2e7f1fbbae0d1f5b197571af9be90d26 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 187 1.7E-30 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS04465 2e7f1fbbae0d1f5b197571af9be90d26 218 Gene3D G3DSA:1.10.150.240 25 75 5.8E-9 T 26-04-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 A4V04_RS05335 2da88e9bcc62d6cfdc53f022b36b52e8 341 Gene3D G3DSA:3.30.43.10 10 73 1.1E-17 T 26-04-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A4V04_RS05335 2da88e9bcc62d6cfdc53f022b36b52e8 341 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 341 72.616 T 26-04-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS05335 2da88e9bcc62d6cfdc53f022b36b52e8 341 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 218 341 6.2E-32 T 26-04-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS05335 2da88e9bcc62d6cfdc53f022b36b52e8 341 Pfam PF01565 FAD binding domain 29 144 9.6E-14 T 26-04-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4V04_RS05335 2da88e9bcc62d6cfdc53f022b36b52e8 341 SUPERFAMILY SSF56176 10 200 4.07E-37 T 26-04-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4V04_RS05335 2da88e9bcc62d6cfdc53f022b36b52e8 341 SUPERFAMILY SSF56194 215 341 5.75E-42 T 26-04-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS05335 2da88e9bcc62d6cfdc53f022b36b52e8 341 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 12 340 7.5E-68 T 26-04-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS05335 2da88e9bcc62d6cfdc53f022b36b52e8 341 Gene3D G3DSA:3.30.465.10 82 241 2.0E-50 T 26-04-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4V04_RS05335 2da88e9bcc62d6cfdc53f022b36b52e8 341 Gene3D G3DSA:3.90.78.10 242 341 1.1E-39 T 26-04-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS05775 91ec47853e84883e750012392419c9e8 452 SMART SM00869 172 442 1.2E-12 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS05775 91ec47853e84883e750012392419c9e8 452 Gene3D G3DSA:2.40.128.130 164 452 8.3E-18 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS05775 91ec47853e84883e750012392419c9e8 452 SUPERFAMILY SSF103515 135 452 1.7E-18 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS07855 a7d9243ee47ddc91eb19101e9d0f4c48 453 PIRSF PIRSF004539 3 451 4.9E-171 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS07855 a7d9243ee47ddc91eb19101e9d0f4c48 453 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 8 449 5.6E-158 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS07855 a7d9243ee47ddc91eb19101e9d0f4c48 453 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 8 382 4.8E-140 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS04545 a4d5afd600cc1755ce7d33b584e0eabd 309 SUPERFAMILY SSF55729 3 137 2.54E-10 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS04545 a4d5afd600cc1755ce7d33b584e0eabd 309 SUPERFAMILY SSF55729 139 298 2.54E-42 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS04545 a4d5afd600cc1755ce7d33b584e0eabd 309 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 124 287 1.5E-20 T 26-04-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal A4V04_RS04545 a4d5afd600cc1755ce7d33b584e0eabd 309 Gene3D G3DSA:3.40.630.30 3 133 1.2E-11 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS04545 a4d5afd600cc1755ce7d33b584e0eabd 309 Gene3D G3DSA:3.40.630.30 134 291 1.5E-46 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS03030 19e9cfc6543a20e1609e3aa2cbd2e87b 111 SMART SM00450 8 107 8.6E-9 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS03030 19e9cfc6543a20e1609e3aa2cbd2e87b 111 Gene3D G3DSA:3.40.250.10 23 100 4.5E-16 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS03030 19e9cfc6543a20e1609e3aa2cbd2e87b 111 SUPERFAMILY SSF52821 22 104 9.04E-17 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS03030 19e9cfc6543a20e1609e3aa2cbd2e87b 111 Pfam PF00581 Rhodanese-like domain 24 100 5.8E-10 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS13115 30c349568f901fe3471f07b4e571a63e 137 Pfam PF01797 Transposase IS200 like 10 131 6.1E-38 T 26-04-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS13115 30c349568f901fe3471f07b4e571a63e 137 Gene3D G3DSA:3.30.70.1290 2 133 2.3E-45 T 26-04-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS13115 30c349568f901fe3471f07b4e571a63e 137 SUPERFAMILY SSF143422 1 132 5.76E-41 T 26-04-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS13115 30c349568f901fe3471f07b4e571a63e 137 SMART SM01321 10 131 3.4E-35 T 26-04-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS01075 ee362ca3c070f9c0ae7aa63bea69178e 211 Pfam PF02581 Thiamine monophosphate synthase/TENI 9 190 5.1E-59 T 26-04-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS01075 ee362ca3c070f9c0ae7aa63bea69178e 211 SUPERFAMILY SSF51391 5 205 8.24E-59 T 26-04-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS01075 ee362ca3c070f9c0ae7aa63bea69178e 211 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 8 203 1.3E-58 T 26-04-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS01075 ee362ca3c070f9c0ae7aa63bea69178e 211 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 7 208 26.527 T 26-04-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS01075 ee362ca3c070f9c0ae7aa63bea69178e 211 Gene3D G3DSA:3.20.20.70 2 209 1.6E-69 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS08375 f139cd49b47aa133657d6df817aa004e 532 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 67 445 9.9E-75 T 26-04-2017 IPR000914 Solute-binding protein family 5 domain A4V04_RS08375 f139cd49b47aa133657d6df817aa004e 532 SUPERFAMILY SSF53850 25 513 2.64E-108 T 26-04-2017 A4V04_RS08375 f139cd49b47aa133657d6df817aa004e 532 PIRSF PIRSF002741 3 525 1.3E-74 T 26-04-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4V04_RS08375 f139cd49b47aa133657d6df817aa004e 532 Gene3D G3DSA:3.90.76.10 36 186 1.6E-27 T 26-04-2017 A4V04_RS08375 f139cd49b47aa133657d6df817aa004e 532 Gene3D G3DSA:3.10.105.10 307 501 3.8E-49 T 26-04-2017 A4V04_RS08375 f139cd49b47aa133657d6df817aa004e 532 Gene3D G3DSA:3.40.190.10 187 306 1.3E-30 T 26-04-2017 A4V04_RS09780 828a6fda101902f41f411f7a396f1ca8 375 Gene3D G3DSA:3.30.70.1070 293 370 5.3E-10 T 26-04-2017 IPR007730 Sporulation-related domain GO:0042834 A4V04_RS09780 828a6fda101902f41f411f7a396f1ca8 375 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 82 196 1.9E-41 T 26-04-2017 IPR012997 Rare lipoprotein A A4V04_RS09780 828a6fda101902f41f411f7a396f1ca8 375 Gene3D G3DSA:2.40.40.10 119 166 6.2E-4 T 26-04-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain A4V04_RS09780 828a6fda101902f41f411f7a396f1ca8 375 SUPERFAMILY SSF110997 297 371 1.19E-9 T 26-04-2017 IPR007730 Sporulation-related domain GO:0042834 A4V04_RS09780 828a6fda101902f41f411f7a396f1ca8 375 Pfam PF05036 Sporulation related domain 296 372 5.4E-11 T 26-04-2017 IPR007730 Sporulation-related domain GO:0042834 A4V04_RS09780 828a6fda101902f41f411f7a396f1ca8 375 SUPERFAMILY SSF50685 73 168 7.32E-9 T 26-04-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain A4V04_RS09780 828a6fda101902f41f411f7a396f1ca8 375 Pfam PF03330 Lytic transglycolase 82 168 4.4E-24 T 26-04-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain A4V04_RS11530 7d62a7b65560e495a8800843d69b67d9 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 158 177 8.7E-57 T 26-04-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS11530 7d62a7b65560e495a8800843d69b67d9 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 250 266 8.7E-57 T 26-04-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS11530 7d62a7b65560e495a8800843d69b67d9 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 305 324 8.7E-57 T 26-04-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS11530 7d62a7b65560e495a8800843d69b67d9 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 196 215 8.7E-57 T 26-04-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS11530 7d62a7b65560e495a8800843d69b67d9 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 127 141 8.7E-57 T 26-04-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS11530 7d62a7b65560e495a8800843d69b67d9 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 275 290 8.7E-57 T 26-04-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS11530 7d62a7b65560e495a8800843d69b67d9 336 SUPERFAMILY SSF51569 6 333 1.9E-141 T 26-04-2017 A4V04_RS11530 7d62a7b65560e495a8800843d69b67d9 336 Pfam PF00490 Delta-aminolevulinic acid dehydratase 10 330 1.2E-136 T 26-04-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS11530 7d62a7b65560e495a8800843d69b67d9 336 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 250 262 - T 26-04-2017 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS11530 7d62a7b65560e495a8800843d69b67d9 336 Gene3D G3DSA:3.20.20.70 6 334 3.3E-148 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS11530 7d62a7b65560e495a8800843d69b67d9 336 PIRSF PIRSF001415 1 334 2.1E-146 T 26-04-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS11530 7d62a7b65560e495a8800843d69b67d9 336 SMART SM01004 7 331 2.9E-235 T 26-04-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 SUPERFAMILY SSF50249 678 758 5.61E-17 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 ProSitePatterns PS01175 Ribonuclease II family signature. 570 594 - T 26-04-2017 IPR022966 Ribonuclease II/R, conserved site A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 Pfam PF08206 Ribonuclease B OB domain 101 146 2.3E-13 T 26-04-2017 IPR013223 Ribonuclease B, N-terminal OB domain A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 Gene3D G3DSA:2.40.50.140 98 131 5.5E-5 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 TIGRFAM TIGR02063 RNase_R: ribonuclease R 35 760 5.8E-224 T 26-04-2017 IPR011805 Ribonuclease R GO:0003723|GO:0004518 A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 97 759 1.3E-184 T 26-04-2017 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 SUPERFAMILY SSF50249 153 250 3.77E-11 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 SUPERFAMILY SSF50249 635 675 4.17E-136 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 SUPERFAMILY SSF50249 234 604 4.17E-136 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 Pfam PF00773 RNB domain 273 602 1.5E-100 T 26-04-2017 A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 SMART SM00316 676 759 1.7E-9 T 26-04-2017 IPR022967 RNA-binding domain, S1 A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 SMART SM00316 94 156 48.0 T 26-04-2017 IPR022967 RNA-binding domain, S1 A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 SMART SM00357 100 159 1.0E-5 T 26-04-2017 IPR011129 Cold shock protein GO:0003676 A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 SUPERFAMILY SSF50249 88 161 3.98E-12 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 Pfam PF00575 S1 RNA binding domain 675 756 1.3E-9 T 26-04-2017 IPR003029 S1 domain GO:0003676 A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 Gene3D G3DSA:2.40.50.140 678 770 3.9E-15 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 SMART SM00955 273 603 1.0E-173 T 26-04-2017 A4V04_RS07410 54af6fcfd699327526298bdededf5530 811 Hamap MF_01895 Ribonuclease R [rnr]. 56 759 49.701 T 26-04-2017 IPR011805 Ribonuclease R GO:0003723|GO:0004518 A4V04_RS01970 b40ce6756b06a7385a0cde6b67469fb8 497 Gene3D G3DSA:3.50.50.60 34 270 2.5E-65 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS01970 b40ce6756b06a7385a0cde6b67469fb8 497 Gene3D G3DSA:3.50.50.60 433 492 2.5E-65 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS01970 b40ce6756b06a7385a0cde6b67469fb8 497 Gene3D G3DSA:3.90.700.10 295 426 5.8E-22 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS01970 b40ce6756b06a7385a0cde6b67469fb8 497 Pfam PF00890 FAD binding domain 45 475 5.8E-50 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS01970 b40ce6756b06a7385a0cde6b67469fb8 497 SUPERFAMILY SSF56425 291 430 2.04E-21 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS01970 b40ce6756b06a7385a0cde6b67469fb8 497 SUPERFAMILY SSF51905 436 496 1.8E-40 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS01970 b40ce6756b06a7385a0cde6b67469fb8 497 SUPERFAMILY SSF51905 38 278 1.8E-40 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS09255 bcb69736e6e09223e6bfa082fcd135f0 130 Gene3D G3DSA:3.30.1130.10 14 124 3.1E-27 T 26-04-2017 A4V04_RS09255 bcb69736e6e09223e6bfa082fcd135f0 130 SMART SM00905 16 124 1.7E-21 T 26-04-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4V04_RS09255 bcb69736e6e09223e6bfa082fcd135f0 130 TIGRFAM TIGR00526 folB_dom: FolB domain 15 123 3.0E-15 T 26-04-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4V04_RS09255 bcb69736e6e09223e6bfa082fcd135f0 130 SUPERFAMILY SSF55620 13 124 5.56E-23 T 26-04-2017 A4V04_RS09255 bcb69736e6e09223e6bfa082fcd135f0 130 Pfam PF02152 Dihydroneopterin aldolase 16 122 2.3E-21 T 26-04-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 Gene3D G3DSA:3.40.50.1260 11 179 5.9E-59 T 26-04-2017 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 PRINTS PR00477 Phosphoglycerate kinase family signature 191 210 1.1E-75 T 26-04-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 PRINTS PR00477 Phosphoglycerate kinase family signature 36 58 1.1E-75 T 26-04-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 1.1E-75 T 26-04-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 PRINTS PR00477 Phosphoglycerate kinase family signature 168 190 1.1E-75 T 26-04-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 PRINTS PR00477 Phosphoglycerate kinase family signature 351 362 1.1E-75 T 26-04-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 PRINTS PR00477 Phosphoglycerate kinase family signature 14 30 1.1E-75 T 26-04-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 PRINTS PR00477 Phosphoglycerate kinase family signature 315 340 1.1E-75 T 26-04-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 PRINTS PR00477 Phosphoglycerate kinase family signature 374 391 1.1E-75 T 26-04-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 1.1E-75 T 26-04-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 PIRSF PIRSF000724 2 402 3.5E-130 T 26-04-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 Pfam PF00162 Phosphoglycerate kinase 11 388 3.2E-134 T 26-04-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 SUPERFAMILY SSF53748 11 397 2.0E-137 T 26-04-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 Gene3D G3DSA:3.40.50.1270 180 386 7.4E-76 T 26-04-2017 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 19 29 - T 26-04-2017 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS07610 f5c7773368b17de89cf14db503602998 402 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 398 37.595 T 26-04-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS05555 07ddd3349125e9e30093a59b6d4699e5 107 Pfam PF06613 KorB C-terminal beta-barrel domain 56 106 1.0E-7 T 26-04-2017 IPR010575 KorB, C-terminal GO:0003677|GO:0045892 A4V04_RS05555 07ddd3349125e9e30093a59b6d4699e5 107 Gene3D G3DSA:2.30.30.150 54 107 2.2E-10 T 26-04-2017 IPR010575 KorB, C-terminal GO:0003677|GO:0045892 A4V04_RS05555 07ddd3349125e9e30093a59b6d4699e5 107 SUPERFAMILY SSF50037 51 107 1.19E-5 T 26-04-2017 IPR008988 Transcriptional repressor, C-terminal A4V04_RS05065 832cf95965b09610f5511db3a8025c8a 201 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 3 193 4.8E-102 T 26-04-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4V04_RS05065 832cf95965b09610f5511db3a8025c8a 201 Pfam PF00574 Clp protease 14 193 4.9E-85 T 26-04-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A4V04_RS05065 832cf95965b09610f5511db3a8025c8a 201 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 113 126 - T 26-04-2017 IPR033135 ClpP, histidine active site A4V04_RS05065 832cf95965b09610f5511db3a8025c8a 201 Gene3D G3DSA:3.90.226.10 4 193 1.4E-86 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS05065 832cf95965b09610f5511db3a8025c8a 201 PRINTS PR00127 Clp protease catalytic subunit P signature 91 108 6.9E-53 T 26-04-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4V04_RS05065 832cf95965b09610f5511db3a8025c8a 201 PRINTS PR00127 Clp protease catalytic subunit P signature 20 35 6.9E-53 T 26-04-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4V04_RS05065 832cf95965b09610f5511db3a8025c8a 201 PRINTS PR00127 Clp protease catalytic subunit P signature 60 80 6.9E-53 T 26-04-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4V04_RS05065 832cf95965b09610f5511db3a8025c8a 201 PRINTS PR00127 Clp protease catalytic subunit P signature 112 131 6.9E-53 T 26-04-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4V04_RS05065 832cf95965b09610f5511db3a8025c8a 201 PRINTS PR00127 Clp protease catalytic subunit P signature 169 188 6.9E-53 T 26-04-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4V04_RS05065 832cf95965b09610f5511db3a8025c8a 201 SUPERFAMILY SSF52096 12 197 2.4E-72 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS05065 832cf95965b09610f5511db3a8025c8a 201 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 91 102 - T 26-04-2017 IPR018215 ClpP, Ser active site A4V04_RS05065 832cf95965b09610f5511db3a8025c8a 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 4 194 44.095 T 26-04-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4V04_RS11435 6ce98450530c47ac3ee89d7c5e1e2728 387 Gene3D G3DSA:3.30.70.20 285 342 1.9E-13 T 26-04-2017 A4V04_RS11435 6ce98450530c47ac3ee89d7c5e1e2728 387 Gene3D G3DSA:3.30.70.20 31 100 4.5E-10 T 26-04-2017 A4V04_RS11435 6ce98450530c47ac3ee89d7c5e1e2728 387 SUPERFAMILY SSF54862 40 102 7.14E-10 T 26-04-2017 A4V04_RS11435 6ce98450530c47ac3ee89d7c5e1e2728 387 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 290 301 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS11435 6ce98450530c47ac3ee89d7c5e1e2728 387 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 323 334 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS11435 6ce98450530c47ac3ee89d7c5e1e2728 387 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 82 93 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS11435 6ce98450530c47ac3ee89d7c5e1e2728 387 SUPERFAMILY SSF54862 266 343 4.06E-18 T 26-04-2017 A4V04_RS11435 6ce98450530c47ac3ee89d7c5e1e2728 387 SUPERFAMILY SSF54862 116 185 4.06E-18 T 26-04-2017 A4V04_RS11435 6ce98450530c47ac3ee89d7c5e1e2728 387 Pfam PF12838 4Fe-4S dicluster domain 289 337 1.5E-8 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS00860 1595ab9ed303830ff8e284d7d268a872 163 SUPERFAMILY SSF55826 10 159 2.49E-38 T 26-04-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4V04_RS00860 1595ab9ed303830ff8e284d7d268a872 163 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 10 156 8.6E-48 T 26-04-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC A4V04_RS00860 1595ab9ed303830ff8e284d7d268a872 163 Pfam PF04073 Aminoacyl-tRNA editing domain 37 150 6.9E-24 T 26-04-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4V04_RS00860 1595ab9ed303830ff8e284d7d268a872 163 PIRSF PIRSF006181 5 162 1.3E-44 T 26-04-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC A4V04_RS00860 1595ab9ed303830ff8e284d7d268a872 163 Gene3D G3DSA:3.90.960.10 3 159 1.1E-45 T 26-04-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4V04_RS02215 19c66333352c9bef98f39f67704cb973 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 5.6E-19 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS02215 19c66333352c9bef98f39f67704cb973 305 Gene3D G3DSA:3.40.190.10 98 234 4.0E-20 T 26-04-2017 A4V04_RS02215 19c66333352c9bef98f39f67704cb973 305 SUPERFAMILY SSF46785 7 86 5.9E-21 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02215 19c66333352c9bef98f39f67704cb973 305 Gene3D G3DSA:1.10.10.10 7 86 3.2E-26 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02215 19c66333352c9bef98f39f67704cb973 305 Pfam PF03466 LysR substrate binding domain 92 300 2.8E-30 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS02215 19c66333352c9bef98f39f67704cb973 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 3.5E-9 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS02215 19c66333352c9bef98f39f67704cb973 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 3.5E-9 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS02215 19c66333352c9bef98f39f67704cb973 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 3.5E-9 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS02215 19c66333352c9bef98f39f67704cb973 305 SUPERFAMILY SSF53850 94 301 6.36E-29 T 26-04-2017 A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 131 141 - T 26-04-2017 IPR022398 Peptidase S8, subtilisin, His-active site A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 SUPERFAMILY SSF51126 536 656 5.34E-6 T 26-04-2017 IPR011050 Pectin lyase fold/virulence factor A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 Pfam PF00082 Subtilase family 83 367 1.4E-33 T 26-04-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 330 340 - T 26-04-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 Pfam PF03797 Autotransporter beta-domain 811 1056 3.9E-19 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 SMART SM00869 812 1074 3.6E-15 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 544 574 1.2E-10 T 26-04-2017 IPR013425 Autotransporter-associated beta strand repeat A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 SUPERFAMILY SSF52743 449 470 1.16E-47 T 26-04-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 SUPERFAMILY SSF52743 226 368 1.16E-47 T 26-04-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 SUPERFAMILY SSF52743 65 191 1.16E-47 T 26-04-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 Gene3D G3DSA:3.40.50.200 54 369 2.4E-49 T 26-04-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 Gene3D G3DSA:3.40.50.200 413 414 2.4E-49 T 26-04-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 Gene3D G3DSA:3.40.50.200 453 470 2.4E-49 T 26-04-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 Pfam PF12951 Passenger-associated-transport-repeat 545 573 1.4E-7 T 26-04-2017 IPR013425 Autotransporter-associated beta strand repeat A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 SUPERFAMILY SSF103515 789 1084 1.44E-26 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 Gene3D G3DSA:2.40.128.130 792 1084 4.7E-26 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 PRINTS PR00723 Subtilisin serine protease family (S8) signature 329 345 2.2E-14 T 26-04-2017 IPR015500 Peptidase S8, subtilisin-related A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 PRINTS PR00723 Subtilisin serine protease family (S8) signature 127 140 2.2E-14 T 26-04-2017 IPR015500 Peptidase S8, subtilisin-related A4V04_RS02785 929c7a2ace8d0431b251de5eda6c9253 1084 PRINTS PR00723 Subtilisin serine protease family (S8) signature 83 102 2.2E-14 T 26-04-2017 IPR015500 Peptidase S8, subtilisin-related A4V04_RS00985 54d3f44c8f2c716603d538bcd192cbcf 355 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 72 85 - T 26-04-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4V04_RS00985 54d3f44c8f2c716603d538bcd192cbcf 355 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 328 9.5E-95 T 26-04-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4V04_RS00985 54d3f44c8f2c716603d538bcd192cbcf 355 Gene3D G3DSA:3.20.20.70 1 335 2.2E-109 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS00985 54d3f44c8f2c716603d538bcd192cbcf 355 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 26-04-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4V04_RS00985 54d3f44c8f2c716603d538bcd192cbcf 355 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 329 4.8E-100 T 26-04-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4V04_RS00985 54d3f44c8f2c716603d538bcd192cbcf 355 SUPERFAMILY SSF51569 1 329 6.01E-105 T 26-04-2017 A4V04_RS00985 54d3f44c8f2c716603d538bcd192cbcf 355 PIRSF PIRSF001359 1 329 9.2E-87 T 26-04-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4V04_RS00985 54d3f44c8f2c716603d538bcd192cbcf 355 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 6.1E-177 T 26-04-2017 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A4V04_RS03260 f9223a5a15bd6bad2c7e951911a0319d 604 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 419 541 1.9E-34 T 26-04-2017 IPR025299 CstA, C-terminal domain A4V04_RS03260 f9223a5a15bd6bad2c7e951911a0319d 604 Pfam PF02554 Carbon starvation protein CstA 1 370 2.9E-149 T 26-04-2017 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A4V04_RS06960 4a494fc2cfbf28df812a7fc7ca3b3bdc 313 Pfam PF00923 Transaldolase 13 306 3.2E-90 T 26-04-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 A4V04_RS06960 4a494fc2cfbf28df812a7fc7ca3b3bdc 313 ProSitePatterns PS00958 Transaldolase active site. 120 137 - T 26-04-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 A4V04_RS06960 4a494fc2cfbf28df812a7fc7ca3b3bdc 313 Gene3D G3DSA:3.20.20.70 1 308 4.6E-113 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS06960 4a494fc2cfbf28df812a7fc7ca3b3bdc 313 SUPERFAMILY SSF51569 1 308 3.04E-101 T 26-04-2017 A4V04_RS06960 4a494fc2cfbf28df812a7fc7ca3b3bdc 313 TIGRFAM TIGR00874 talAB: transaldolase 2 308 2.1E-119 T 26-04-2017 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 A4V04_RS06960 4a494fc2cfbf28df812a7fc7ca3b3bdc 313 ProSitePatterns PS01054 Transaldolase signature 1. 30 38 - T 26-04-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 A4V04_RS06925 3708520917e27b1321636250947c9284 214 SUPERFAMILY SSF53335 31 213 5.18E-37 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS06925 3708520917e27b1321636250947c9284 214 Gene3D G3DSA:3.40.50.150 5 214 1.1E-71 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS06925 3708520917e27b1321636250947c9284 214 PIRSF PIRSF005461 2 214 9.2E-75 T 26-04-2017 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 A4V04_RS06925 3708520917e27b1321636250947c9284 214 Pfam PF01728 FtsJ-like methyltransferase 32 212 4.7E-60 T 26-04-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 A4V04_RS06925 3708520917e27b1321636250947c9284 214 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 12 213 30.451 T 26-04-2017 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 A4V04_RS04470 23d3af4557fd8f052a28c1d90da9e472 485 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 421 4.3E-152 T 26-04-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 A4V04_RS04470 23d3af4557fd8f052a28c1d90da9e472 485 Gene3D G3DSA:2.40.50.140 29 119 1.6E-30 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS04470 23d3af4557fd8f052a28c1d90da9e472 485 Pfam PF10150 Ribonuclease E/G family 115 388 2.8E-100 T 26-04-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A4V04_RS04470 23d3af4557fd8f052a28c1d90da9e472 485 SUPERFAMILY SSF50249 38 119 3.18E-16 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS04470 23d3af4557fd8f052a28c1d90da9e472 485 SMART SM00316 36 113 9.0E-7 T 26-04-2017 IPR022967 RNA-binding domain, S1 A4V04_RS07300 81e8f540b2694b2225e3d5f51cc6264a 394 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 50 375 1.1E-45 T 26-04-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4V04_RS07300 81e8f540b2694b2225e3d5f51cc6264a 394 PIRSF PIRSF001413 1 394 2.9E-171 T 26-04-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4V04_RS07300 81e8f540b2694b2225e3d5f51cc6264a 394 SUPERFAMILY SSF53686 3 385 6.16E-146 T 26-04-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4V04_RS07300 81e8f540b2694b2225e3d5f51cc6264a 394 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 78 92 - T 26-04-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4V04_RS07300 81e8f540b2694b2225e3d5f51cc6264a 394 Gene3D G3DSA:3.40.50.1100 175 390 6.6E-93 T 26-04-2017 A4V04_RS07300 81e8f540b2694b2225e3d5f51cc6264a 394 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 388 51.633 T 26-04-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4V04_RS07300 81e8f540b2694b2225e3d5f51cc6264a 394 Gene3D G3DSA:3.40.50.1100 95 174 5.8E-19 T 26-04-2017 A4V04_RS07300 81e8f540b2694b2225e3d5f51cc6264a 394 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 4 387 4.4E-197 T 26-04-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4V04_RS01795 e6b2ff4e34d595c311e02ccc501366e1 170 Pfam PF10502 Signal peptidase, peptidase S26 41 169 9.6E-24 T 26-04-2017 IPR019533 Peptidase S26 A4V04_RS01795 e6b2ff4e34d595c311e02ccc501366e1 170 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 54 167 5.6E-13 T 26-04-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4V04_RS01795 e6b2ff4e34d595c311e02ccc501366e1 170 Gene3D G3DSA:2.10.109.10 132 170 9.8E-13 T 26-04-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain A4V04_RS01795 e6b2ff4e34d595c311e02ccc501366e1 170 Gene3D G3DSA:2.10.109.10 54 95 9.8E-13 T 26-04-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain A4V04_RS01795 e6b2ff4e34d595c311e02ccc501366e1 170 SUPERFAMILY SSF51306 43 170 2.77E-23 T 26-04-2017 IPR015927 Peptidase S24/S26A/S26B/S26C A4V04_RS11710 2768e40759c7133c145a29c87399f5d0 447 Pfam PF00589 Phage integrase family 230 345 1.2E-8 T 26-04-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS11710 2768e40759c7133c145a29c87399f5d0 447 Gene3D G3DSA:1.10.150.130 108 203 2.7E-8 T 26-04-2017 IPR023109 Integrase/recombinase, N-terminal A4V04_RS11710 2768e40759c7133c145a29c87399f5d0 447 Gene3D G3DSA:1.10.443.10 228 417 7.3E-13 T 26-04-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS11710 2768e40759c7133c145a29c87399f5d0 447 SUPERFAMILY SSF56349 107 426 3.53E-36 T 26-04-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4V04_RS11710 2768e40759c7133c145a29c87399f5d0 447 Pfam PF13356 Domain of unknown function (DUF4102) 20 91 3.1E-10 T 26-04-2017 IPR025166 Domain of unknown function DUF4102 A4V04_RS12545 d821a675793ac57dc7e92fd56120b7b0 626 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 255 625 1.9E-69 T 26-04-2017 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 A4V04_RS12545 d821a675793ac57dc7e92fd56120b7b0 626 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 8 625 19.964 T 26-04-2017 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 A4V04_RS12545 d821a675793ac57dc7e92fd56120b7b0 626 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 113 230 9.5E-33 T 26-04-2017 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 A4V04_RS12545 d821a675793ac57dc7e92fd56120b7b0 626 SUPERFAMILY SSF51905 255 479 4.86E-33 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12545 d821a675793ac57dc7e92fd56120b7b0 626 SUPERFAMILY SSF51905 548 623 4.86E-33 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12545 d821a675793ac57dc7e92fd56120b7b0 626 Gene3D G3DSA:3.50.50.60 383 461 1.8E-22 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12545 d821a675793ac57dc7e92fd56120b7b0 626 Gene3D G3DSA:3.50.50.60 548 624 1.8E-22 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12545 d821a675793ac57dc7e92fd56120b7b0 626 Gene3D G3DSA:3.50.50.60 254 323 1.8E-22 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12545 d821a675793ac57dc7e92fd56120b7b0 626 Pfam PF01266 FAD dependent oxidoreductase 254 600 2.4E-37 T 26-04-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4V04_RS12545 d821a675793ac57dc7e92fd56120b7b0 626 Gene3D G3DSA:3.40.50.150 13 239 1.4E-81 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS08465 be62627490f269ba0c3079f3e72731df 429 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 327 424 4.5E-24 T 26-04-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4V04_RS08465 be62627490f269ba0c3079f3e72731df 429 SUPERFAMILY SSF51735 170 321 1.75E-35 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS08465 be62627490f269ba0c3079f3e72731df 429 SUPERFAMILY SSF69742 1 164 3.14E-44 T 26-04-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4V04_RS08465 be62627490f269ba0c3079f3e72731df 429 PIRSF PIRSF000445 1 428 5.7E-144 T 26-04-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4V04_RS08465 be62627490f269ba0c3079f3e72731df 429 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 426 29.256 T 26-04-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4V04_RS08465 be62627490f269ba0c3079f3e72731df 429 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 162 1.1E-45 T 26-04-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4V04_RS08465 be62627490f269ba0c3079f3e72731df 429 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 178 312 7.5E-45 T 26-04-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A4V04_RS08465 be62627490f269ba0c3079f3e72731df 429 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 418 5.5E-131 T 26-04-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4V04_RS08465 be62627490f269ba0c3079f3e72731df 429 SUPERFAMILY SSF69075 323 424 2.09E-24 T 26-04-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4V04_RS08465 be62627490f269ba0c3079f3e72731df 429 Gene3D G3DSA:3.40.50.720 189 364 2.3E-37 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS08465 be62627490f269ba0c3079f3e72731df 429 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 105 128 - T 26-04-2017 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4V04_RS07605 e84ed5ffccc43a8be128f1cc85a960ba 269 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 15 268 7.6E-76 T 26-04-2017 IPR004872 Lipoprotein NlpA family A4V04_RS07605 e84ed5ffccc43a8be128f1cc85a960ba 269 Gene3D G3DSA:3.40.190.10 29 159 5.4E-53 T 26-04-2017 A4V04_RS07605 e84ed5ffccc43a8be128f1cc85a960ba 269 Pfam PF03180 NLPA lipoprotein 32 268 1.2E-93 T 26-04-2017 IPR004872 Lipoprotein NlpA family A4V04_RS07605 e84ed5ffccc43a8be128f1cc85a960ba 269 SUPERFAMILY SSF53850 31 268 5.75E-80 T 26-04-2017 A4V04_RS07605 e84ed5ffccc43a8be128f1cc85a960ba 269 PIRSF PIRSF002854 1 269 2.1E-94 T 26-04-2017 IPR004872 Lipoprotein NlpA family A4V04_RS11380 6607f8c38ef0efc414ad005faec0162d 211 Gene3D G3DSA:3.30.70.20 68 111 9.3E-23 T 26-04-2017 A4V04_RS11380 6607f8c38ef0efc414ad005faec0162d 211 SUPERFAMILY SSF54862 1 197 1.57E-56 T 26-04-2017 A4V04_RS11380 6607f8c38ef0efc414ad005faec0162d 211 Pfam PF13247 4Fe-4S dicluster domain 51 111 5.2E-13 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS11380 6607f8c38ef0efc414ad005faec0162d 211 Gene3D G3DSA:3.30.70.20 129 182 1.2E-11 T 26-04-2017 A4V04_RS11380 6607f8c38ef0efc414ad005faec0162d 211 Pfam PF12800 4Fe-4S binding domain 11 25 0.12 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS11380 6607f8c38ef0efc414ad005faec0162d 211 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS11380 6607f8c38ef0efc414ad005faec0162d 211 Gene3D G3DSA:3.30.70.20 2 67 4.9E-13 T 26-04-2017 A4V04_RS11425 c080a1ed86c315c6bc46d84f18b9112b 201 Pfam PF12838 4Fe-4S dicluster domain 133 175 4.1E-8 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS11425 c080a1ed86c315c6bc46d84f18b9112b 201 Pfam PF12838 4Fe-4S dicluster domain 52 106 3.5E-10 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS11425 c080a1ed86c315c6bc46d84f18b9112b 201 SUPERFAMILY SSF54862 50 178 1.88E-20 T 26-04-2017 A4V04_RS11425 c080a1ed86c315c6bc46d84f18b9112b 201 Gene3D G3DSA:3.30.70.20 97 136 1.0E-6 T 26-04-2017 A4V04_RS11425 c080a1ed86c315c6bc46d84f18b9112b 201 Gene3D G3DSA:3.30.70.20 51 96 5.4E-12 T 26-04-2017 A4V04_RS11425 c080a1ed86c315c6bc46d84f18b9112b 201 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 53 64 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS11425 c080a1ed86c315c6bc46d84f18b9112b 201 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 92 103 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS11425 c080a1ed86c315c6bc46d84f18b9112b 201 Gene3D G3DSA:3.30.70.20 137 185 3.5E-13 T 26-04-2017 A4V04_RS11425 c080a1ed86c315c6bc46d84f18b9112b 201 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 161 172 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 SUPERFAMILY SSF52374 427 679 2.7E-143 T 26-04-2017 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 SUPERFAMILY SSF52374 5 232 2.7E-143 T 26-04-2017 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 Pfam PF08264 Anticodon-binding domain of tRNA 712 836 5.3E-17 T 26-04-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 877 0.0 T 26-04-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 26-04-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 Pfam PF09334 tRNA synthetases class I (M) 41 177 1.3E-19 T 26-04-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 536 558 3.5E-47 T 26-04-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 191 204 3.5E-47 T 26-04-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 569 579 3.5E-47 T 26-04-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 159 175 3.5E-47 T 26-04-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 133 150 3.5E-47 T 26-04-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 221 240 3.5E-47 T 26-04-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 498 516 3.5E-47 T 26-04-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 877 22.36 T 26-04-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 Gene3D G3DSA:1.10.730.10 661 813 2.5E-36 T 26-04-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 SUPERFAMILY SSF47323 678 877 9.91E-31 T 26-04-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 Gene3D G3DSA:3.40.50.620 4 232 9.9E-146 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 Gene3D G3DSA:3.40.50.620 631 660 9.9E-146 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 Gene3D G3DSA:3.40.50.620 435 585 9.9E-146 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 228 414 8.8E-67 T 26-04-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 Gene3D G3DSA:3.90.740.10 233 434 3.0E-43 T 26-04-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 SUPERFAMILY SSF50677 238 426 8.06E-53 T 26-04-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 631 662 1.0E-4 T 26-04-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS04925 d3f0dc29988301a62e1688b188921a69 877 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 428 584 4.4E-8 T 26-04-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS08215 63e829d5697261ece80eba6110cc8c1b 117 Gene3D G3DSA:3.90.10.10 27 110 7.3E-12 T 26-04-2017 A4V04_RS08215 63e829d5697261ece80eba6110cc8c1b 117 SUPERFAMILY SSF48695 15 105 2.1E-15 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS08215 63e829d5697261ece80eba6110cc8c1b 117 Pfam PF14537 Cytochrome c3 31 105 2.4E-16 T 26-04-2017 A4V04_RS01685 eaaebffede04fce79842c71f45250059 849 Gene3D G3DSA:2.20.25.90 40 101 8.5E-15 T 26-04-2017 A4V04_RS01685 eaaebffede04fce79842c71f45250059 849 SUPERFAMILY SSF53706 44 709 4.32E-123 T 26-04-2017 A4V04_RS01685 eaaebffede04fce79842c71f45250059 849 Pfam PF00384 Molybdopterin oxidoreductase 100 513 5.5E-37 T 26-04-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS01685 eaaebffede04fce79842c71f45250059 849 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 44 93 4.0E-8 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS01685 eaaebffede04fce79842c71f45250059 849 Gene3D G3DSA:3.40.228.10 182 388 1.6E-48 T 26-04-2017 A4V04_RS01685 eaaebffede04fce79842c71f45250059 849 Gene3D G3DSA:3.40.50.740 102 181 2.8E-35 T 26-04-2017 A4V04_RS01685 eaaebffede04fce79842c71f45250059 849 Gene3D G3DSA:3.40.50.740 389 655 2.8E-35 T 26-04-2017 A4V04_RS01685 eaaebffede04fce79842c71f45250059 849 Pfam PF01568 Molydopterin dinucleotide binding domain 743 831 2.7E-14 T 26-04-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4V04_RS01685 eaaebffede04fce79842c71f45250059 849 Gene3D G3DSA:2.40.40.20 691 844 2.4E-29 T 26-04-2017 A4V04_RS01685 eaaebffede04fce79842c71f45250059 849 SUPERFAMILY SSF50692 700 844 4.29E-26 T 26-04-2017 IPR009010 Aspartate decarboxylase-like domain A4V04_RS01685 eaaebffede04fce79842c71f45250059 849 SMART SM00926 43 97 2.6E-6 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1132 1159 - T 26-04-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 Gene3D G3DSA:3.40.228.10 488 597 3.3E-65 T 26-04-2017 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 Gene3D G3DSA:3.40.228.10 217 335 3.3E-65 T 26-04-2017 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 Gene3D G3DSA:3.40.50.740 598 794 2.5E-50 T 26-04-2017 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 Pfam PF00384 Molybdopterin oxidoreductase 108 837 3.0E-128 T 26-04-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 Gene3D G3DSA:2.20.25.90 52 98 3.6E-29 T 26-04-2017 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 10 40 1.0E-10 T 26-04-2017 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.99.4 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 SMART SM00926 43 105 5.6E-7 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 Gene3D G3DSA:2.40.40.20 1062 1241 1.5E-33 T 26-04-2017 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 26-04-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 SUPERFAMILY SSF50692 1092 1241 3.16E-40 T 26-04-2017 IPR009010 Aspartate decarboxylase-like domain A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 8 1242 0.0 T 26-04-2017 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 Pfam PF01568 Molydopterin dinucleotide binding domain 1094 1196 7.0E-19 T 26-04-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 781 798 - T 26-04-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 SUPERFAMILY SSF53706 14 1072 3.35E-300 T 26-04-2017 A4V04_RS11035 958be3b28d66dc3c90a1ee08081fe7c6 1252 Gene3D G3DSA:3.40.50.740 108 189 2.3E-6 T 26-04-2017 A4V04_RS00835 63bbd8cd0707665792b1bf2fba66b136 214 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 2 195 7.9E-69 T 26-04-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A4V04_RS00835 63bbd8cd0707665792b1bf2fba66b136 214 Pfam PF00551 Formyl transferase 2 186 1.1E-60 T 26-04-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4V04_RS00835 63bbd8cd0707665792b1bf2fba66b136 214 SUPERFAMILY SSF53328 2 198 1.57E-60 T 26-04-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4V04_RS00835 63bbd8cd0707665792b1bf2fba66b136 214 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 138 161 - T 26-04-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4V04_RS00835 63bbd8cd0707665792b1bf2fba66b136 214 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 192 30.954 T 26-04-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A4V04_RS00835 63bbd8cd0707665792b1bf2fba66b136 214 Gene3D G3DSA:3.40.50.170 1 198 4.0E-67 T 26-04-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4V04_RS09215 e3beeeed26830153602b9c4d0ae4e5a9 391 Pfam PF03453 MoeA N-terminal region (domain I and II) 23 154 1.5E-20 T 26-04-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS09215 e3beeeed26830153602b9c4d0ae4e5a9 391 SUPERFAMILY SSF63867 316 385 8.83E-6 T 26-04-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS09215 e3beeeed26830153602b9c4d0ae4e5a9 391 Gene3D G3DSA:3.40.980.10 149 318 6.7E-30 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS09215 e3beeeed26830153602b9c4d0ae4e5a9 391 SUPERFAMILY SSF63882 23 163 3.14E-27 T 26-04-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS09215 e3beeeed26830153602b9c4d0ae4e5a9 391 Gene3D G3DSA:2.170.190.11 45 104 5.4E-6 T 26-04-2017 A4V04_RS09215 e3beeeed26830153602b9c4d0ae4e5a9 391 SMART SM00852 167 306 2.2E-6 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS09215 e3beeeed26830153602b9c4d0ae4e5a9 391 Gene3D G3DSA:2.40.340.10 319 385 2.8E-5 T 26-04-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS09215 e3beeeed26830153602b9c4d0ae4e5a9 391 Gene3D G3DSA:3.90.105.10 129 148 6.5E-11 T 26-04-2017 A4V04_RS09215 e3beeeed26830153602b9c4d0ae4e5a9 391 Gene3D G3DSA:3.90.105.10 24 44 6.5E-11 T 26-04-2017 A4V04_RS09215 e3beeeed26830153602b9c4d0ae4e5a9 391 Pfam PF00994 Probable molybdopterin binding domain 167 304 1.2E-14 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS09215 e3beeeed26830153602b9c4d0ae4e5a9 391 SUPERFAMILY SSF53218 164 305 1.31E-20 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS04965 cd99161fa901c859e722561c9fc2c1b0 640 SUPERFAMILY SSF54534 262 373 6.08E-34 T 26-04-2017 A4V04_RS04965 cd99161fa901c859e722561c9fc2c1b0 640 Gene3D G3DSA:3.10.50.40 257 394 6.5E-46 T 26-04-2017 A4V04_RS04965 cd99161fa901c859e722561c9fc2c1b0 640 Pfam PF13616 PPIC-type PPIASE domain 259 371 2.4E-35 T 26-04-2017 A4V04_RS04965 cd99161fa901c859e722561c9fc2c1b0 640 SUPERFAMILY SSF109998 41 166 9.02E-19 T 26-04-2017 IPR027304 Trigger factor/SurA domain A4V04_RS04965 cd99161fa901c859e722561c9fc2c1b0 640 SUPERFAMILY SSF109998 200 238 9.02E-19 T 26-04-2017 IPR027304 Trigger factor/SurA domain A4V04_RS04965 cd99161fa901c859e722561c9fc2c1b0 640 Pfam PF13624 SurA N-terminal domain 1 159 3.3E-35 T 26-04-2017 A4V04_RS12085 c4c34260c082581abc67a5f798c545cc 444 Pfam PF00209 Sodium:neurotransmitter symporter family 148 441 1.1E-28 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS12085 c4c34260c082581abc67a5f798c545cc 444 Pfam PF00209 Sodium:neurotransmitter symporter family 6 117 2.4E-22 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS12085 c4c34260c082581abc67a5f798c545cc 444 SUPERFAMILY SSF161070 6 443 5.62E-116 T 26-04-2017 A4V04_RS12085 c4c34260c082581abc67a5f798c545cc 444 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 1.6E-12 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS12085 c4c34260c082581abc67a5f798c545cc 444 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 1.6E-12 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS12085 c4c34260c082581abc67a5f798c545cc 444 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 310 330 1.6E-12 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS12085 c4c34260c082581abc67a5f798c545cc 444 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 86 112 1.6E-12 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS00145 82eba72461c4d5e8df47c5a8a65b9e65 497 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 86 8.5E-15 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS00145 82eba72461c4d5e8df47c5a8a65b9e65 497 Gene3D G3DSA:3.40.640.10 164 378 6.0E-48 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS00145 82eba72461c4d5e8df47c5a8a65b9e65 497 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 5.3E-6 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS00145 82eba72461c4d5e8df47c5a8a65b9e65 497 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 5.3E-6 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS00145 82eba72461c4d5e8df47c5a8a65b9e65 497 SMART SM00345 27 86 2.0E-14 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS00145 82eba72461c4d5e8df47c5a8a65b9e65 497 Gene3D G3DSA:1.10.10.10 17 88 9.2E-22 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS00145 82eba72461c4d5e8df47c5a8a65b9e65 497 Pfam PF00155 Aminotransferase class I and II 163 462 1.8E-15 T 26-04-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4V04_RS00145 82eba72461c4d5e8df47c5a8a65b9e65 497 SUPERFAMILY SSF46785 19 92 2.58E-18 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS00145 82eba72461c4d5e8df47c5a8a65b9e65 497 SUPERFAMILY SSF53383 108 491 1.01E-69 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS09125 cd8060bcde3fc2f31f39d9814376ab99 196 Gene3D G3DSA:3.40.50.2300 3 124 3.2E-27 T 26-04-2017 A4V04_RS09125 cd8060bcde3fc2f31f39d9814376ab99 196 SMART SM00448 1 112 1.3E-20 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS09125 cd8060bcde3fc2f31f39d9814376ab99 196 SMART SM00421 132 189 2.3E-20 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS09125 cd8060bcde3fc2f31f39d9814376ab99 196 Pfam PF00196 Bacterial regulatory proteins, luxR family 134 187 9.5E-18 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS09125 cd8060bcde3fc2f31f39d9814376ab99 196 Pfam PF00072 Response regulator receiver domain 3 112 1.5E-21 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS09125 cd8060bcde3fc2f31f39d9814376ab99 196 Gene3D G3DSA:1.10.10.10 125 194 1.2E-20 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09125 cd8060bcde3fc2f31f39d9814376ab99 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 177 1.4E-12 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS09125 cd8060bcde3fc2f31f39d9814376ab99 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 135 149 1.4E-12 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS09125 cd8060bcde3fc2f31f39d9814376ab99 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 165 1.4E-12 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS09125 cd8060bcde3fc2f31f39d9814376ab99 196 SUPERFAMILY SSF52172 4 163 4.13E-28 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS08540 dbb0722921ddd5daa5952f6a750908b3 228 Pfam PF00072 Response regulator receiver domain 8 109 7.4E-11 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS08540 dbb0722921ddd5daa5952f6a750908b3 228 SUPERFAMILY SSF46894 157 226 1.05E-19 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS08540 dbb0722921ddd5daa5952f6a750908b3 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 217 1.8E-18 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08540 dbb0722921ddd5daa5952f6a750908b3 228 SMART SM00421 163 220 7.5E-18 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08540 dbb0722921ddd5daa5952f6a750908b3 228 SMART SM00448 6 120 1.4E-7 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS08540 dbb0722921ddd5daa5952f6a750908b3 228 Gene3D G3DSA:3.40.50.2300 5 123 1.2E-13 T 26-04-2017 A4V04_RS08540 dbb0722921ddd5daa5952f6a750908b3 228 Gene3D G3DSA:1.10.10.10 124 227 1.5E-25 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS08540 dbb0722921ddd5daa5952f6a750908b3 228 SUPERFAMILY SSF52172 6 138 3.98E-15 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS08540 dbb0722921ddd5daa5952f6a750908b3 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 2.9E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08540 dbb0722921ddd5daa5952f6a750908b3 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 2.9E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS08540 dbb0722921ddd5daa5952f6a750908b3 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 2.9E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS11130 b33c7fb4bc8796b318cf45a853d1e0d9 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 8.8E-66 T 26-04-2017 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11130 b33c7fb4bc8796b318cf45a853d1e0d9 144 Gene3D G3DSA:3.30.1550.10 2 72 3.1E-37 T 26-04-2017 IPR020784 Ribosomal protein L11, N-terminal A4V04_RS11130 b33c7fb4bc8796b318cf45a853d1e0d9 144 SMART SM00649 9 141 8.3E-87 T 26-04-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A4V04_RS11130 b33c7fb4bc8796b318cf45a853d1e0d9 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 26-04-2017 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11130 b33c7fb4bc8796b318cf45a853d1e0d9 144 Gene3D G3DSA:1.10.10.250 73 141 4.7E-32 T 26-04-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A4V04_RS11130 b33c7fb4bc8796b318cf45a853d1e0d9 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 7.0E-30 T 26-04-2017 IPR020784 Ribosomal protein L11, N-terminal A4V04_RS11130 b33c7fb4bc8796b318cf45a853d1e0d9 144 SUPERFAMILY SSF46906 68 141 1.83E-27 T 26-04-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A4V04_RS11130 b33c7fb4bc8796b318cf45a853d1e0d9 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 1.0E-15 T 26-04-2017 A4V04_RS11130 b33c7fb4bc8796b318cf45a853d1e0d9 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.684 T 26-04-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A4V04_RS11130 b33c7fb4bc8796b318cf45a853d1e0d9 144 SUPERFAMILY SSF54747 3 73 1.57E-30 T 26-04-2017 IPR020784 Ribosomal protein L11, N-terminal A4V04_RS11130 b33c7fb4bc8796b318cf45a853d1e0d9 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 5.9E-25 T 26-04-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 SUPERFAMILY SSF52540 44 89 2.88E-36 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 SUPERFAMILY SSF52540 465 581 2.88E-36 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 Pfam PF12344 Ultra-violet resistance protein B 558 600 6.7E-22 T 26-04-2017 IPR024759 UvrB, YAD/RRR-motif-containing domain A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 Gene3D G3DSA:3.40.50.300 395 416 1.2E-51 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 Gene3D G3DSA:3.40.50.300 12 96 1.2E-51 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 Gene3D G3DSA:3.40.50.300 285 345 1.2E-51 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 Gene3D G3DSA:3.40.50.300 425 586 3.6E-41 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 12 665 0.0 T 26-04-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 SMART SM00487 16 432 4.5E-31 T 26-04-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 Gene3D G3DSA:4.10.860.10 629 671 1.6E-16 T 26-04-2017 IPR001943 UVR domain GO:0005515 A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 Pfam PF00271 Helicase conserved C-terminal domain 440 551 3.4E-20 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 SMART SM00490 466 552 2.1E-20 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 SUPERFAMILY SSF52540 11 421 1.88E-133 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 SUPERFAMILY SSF46600 625 669 4.84E-11 T 26-04-2017 IPR001943 UVR domain GO:0005515 A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 Pfam PF04851 Type III restriction enzyme, res subunit 22 146 1.4E-8 T 26-04-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 Pfam PF02151 UvrB/uvrC motif 634 668 1.1E-9 T 26-04-2017 IPR001943 UVR domain GO:0005515 A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 Hamap MF_00204 UvrABC system protein B [uvrB]. 10 668 43.132 T 26-04-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 A4V04_RS13205 dcb64e25e469a9325456fc08b67dbcfa 681 Gene3D G3DSA:3.30.2060.10 168 238 1.4E-10 T 26-04-2017 A4V04_RS10750 8252b53035b559b274a8664c29cf5351 251 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 157 171 - T 26-04-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A4V04_RS10750 8252b53035b559b274a8664c29cf5351 251 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 18 248 36.3 T 26-04-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A4V04_RS10750 8252b53035b559b274a8664c29cf5351 251 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 38 53 - T 26-04-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A4V04_RS10750 8252b53035b559b274a8664c29cf5351 251 Pfam PF01209 ubiE/COQ5 methyltransferase family 22 248 4.5E-80 T 26-04-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A4V04_RS10750 8252b53035b559b274a8664c29cf5351 251 SUPERFAMILY SSF53335 17 242 5.47E-43 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS10750 8252b53035b559b274a8664c29cf5351 251 Gene3D G3DSA:3.40.50.150 26 242 2.7E-50 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS10750 8252b53035b559b274a8664c29cf5351 251 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 27 248 8.8E-79 T 26-04-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A4V04_RS05620 dfe61b5e727406c3db2d81a463fd09df 228 Gene3D G3DSA:3.40.50.1360 4 138 1.6E-49 T 26-04-2017 A4V04_RS05620 dfe61b5e727406c3db2d81a463fd09df 228 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 4 218 28.884 T 26-04-2017 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A4V04_RS05620 dfe61b5e727406c3db2d81a463fd09df 228 SUPERFAMILY SSF75445 128 199 7.46E-15 T 26-04-2017 A4V04_RS05620 dfe61b5e727406c3db2d81a463fd09df 228 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 7 215 8.6E-61 T 26-04-2017 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A4V04_RS05620 dfe61b5e727406c3db2d81a463fd09df 228 SUPERFAMILY SSF100950 4 148 4.52E-38 T 26-04-2017 A4V04_RS05620 dfe61b5e727406c3db2d81a463fd09df 228 Gene3D G3DSA:3.30.70.260 139 197 2.2E-17 T 26-04-2017 A4V04_RS05620 dfe61b5e727406c3db2d81a463fd09df 228 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 50 214 1.7E-50 T 26-04-2017 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A4V04_RS03305 62e279426f98de3a590f9e885bd66f71 611 Gene3D G3DSA:2.30.38.10 405 460 2.3E-20 T 26-04-2017 A4V04_RS03305 62e279426f98de3a590f9e885bd66f71 611 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 26-04-2017 IPR020845 AMP-binding, conserved site A4V04_RS03305 62e279426f98de3a590f9e885bd66f71 611 Pfam PF00501 AMP-binding enzyme 18 477 8.6E-95 T 26-04-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4V04_RS03305 62e279426f98de3a590f9e885bd66f71 611 SUPERFAMILY SSF56801 9 291 1.57E-119 T 26-04-2017 A4V04_RS03305 62e279426f98de3a590f9e885bd66f71 611 SUPERFAMILY SSF56801 346 607 1.57E-119 T 26-04-2017 A4V04_RS03305 62e279426f98de3a590f9e885bd66f71 611 Gene3D G3DSA:3.40.50.980 195 286 3.2E-37 T 26-04-2017 A4V04_RS03305 62e279426f98de3a590f9e885bd66f71 611 Gene3D G3DSA:3.40.50.980 343 404 3.2E-37 T 26-04-2017 A4V04_RS03305 62e279426f98de3a590f9e885bd66f71 611 Gene3D G3DSA:3.40.50.980 13 194 2.4E-33 T 26-04-2017 A4V04_RS11765 9e7cb12b582bc8f5a23c554f7d3d4461 175 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 31 45 3.4E-8 T 26-04-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4V04_RS11765 9e7cb12b582bc8f5a23c554f7d3d4461 175 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 64 84 3.4E-8 T 26-04-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4V04_RS11765 9e7cb12b582bc8f5a23c554f7d3d4461 175 Pfam PF01555 DNA methylase 32 155 3.8E-18 T 26-04-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A4V04_RS11765 9e7cb12b582bc8f5a23c554f7d3d4461 175 SUPERFAMILY SSF53335 5 156 1.23E-30 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS11765 9e7cb12b582bc8f5a23c554f7d3d4461 175 Gene3D G3DSA:3.40.50.150 12 153 1.0E-31 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS11765 9e7cb12b582bc8f5a23c554f7d3d4461 175 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 35 41 - T 26-04-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4V04_RS11835 8c961f68e2f72857602f27c0d708e186 306 SMART SM00382 38 218 2.3E-9 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS11835 8c961f68e2f72857602f27c0d708e186 306 SUPERFAMILY SSF52540 8 236 5.7E-59 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11835 8c961f68e2f72857602f27c0d708e186 306 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS11835 8c961f68e2f72857602f27c0d708e186 306 Gene3D G3DSA:3.40.50.300 9 237 5.8E-63 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11835 8c961f68e2f72857602f27c0d708e186 306 Pfam PF00005 ABC transporter 29 171 1.3E-30 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS11465 345296d0411d09de57a9e145c13940e1 347 PIRSF PIRSF005378 1 345 1.8E-83 T 26-04-2017 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 A4V04_RS11465 345296d0411d09de57a9e145c13940e1 347 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 5 329 1.5E-84 T 26-04-2017 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 A4V04_RS11465 345296d0411d09de57a9e145c13940e1 347 Gene3D G3DSA:3.65.10.20 277 337 3.5E-66 T 26-04-2017 IPR023797 RNA 3'-terminal phosphate cyclase domain A4V04_RS11465 345296d0411d09de57a9e145c13940e1 347 Gene3D G3DSA:3.65.10.20 3 176 3.5E-66 T 26-04-2017 IPR023797 RNA 3'-terminal phosphate cyclase domain A4V04_RS11465 345296d0411d09de57a9e145c13940e1 347 Pfam PF01137 RNA 3'-terminal phosphate cyclase 11 329 1.1E-64 T 26-04-2017 IPR023797 RNA 3'-terminal phosphate cyclase domain A4V04_RS11465 345296d0411d09de57a9e145c13940e1 347 SUPERFAMILY SSF55205 4 182 1.24E-50 T 26-04-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A4V04_RS04175 b70961ec7ce21a21607e6959e9ef03da 511 SUPERFAMILY SSF51905 36 289 1.66E-34 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04175 b70961ec7ce21a21607e6959e9ef03da 511 SUPERFAMILY SSF51905 451 509 1.66E-34 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04175 b70961ec7ce21a21607e6959e9ef03da 511 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 44 66 7.7E-5 T 26-04-2017 A4V04_RS04175 b70961ec7ce21a21607e6959e9ef03da 511 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 501 511 7.7E-5 T 26-04-2017 A4V04_RS04175 b70961ec7ce21a21607e6959e9ef03da 511 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 35 2.2E-4 T 26-04-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A4V04_RS04175 b70961ec7ce21a21607e6959e9ef03da 511 SUPERFAMILY SSF56425 282 443 1.41E-24 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04175 b70961ec7ce21a21607e6959e9ef03da 511 Gene3D G3DSA:3.90.700.10 307 443 1.7E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04175 b70961ec7ce21a21607e6959e9ef03da 511 Gene3D G3DSA:3.50.50.60 30 279 6.7E-59 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04175 b70961ec7ce21a21607e6959e9ef03da 511 Gene3D G3DSA:3.50.50.60 448 508 6.7E-59 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04175 b70961ec7ce21a21607e6959e9ef03da 511 Pfam PF00890 FAD binding domain 44 490 5.9E-49 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02905 4690fd667f12a84af2af954a196ba433 296 SUPERFAMILY SSF51306 90 292 4.19E-66 T 26-04-2017 IPR015927 Peptidase S24/S26A/S26B/S26C A4V04_RS02905 4690fd667f12a84af2af954a196ba433 296 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 78 285 1.4E-51 T 26-04-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4V04_RS02905 4690fd667f12a84af2af954a196ba433 296 ProSitePatterns PS00761 Signal peptidases I signature 3. 251 264 - T 26-04-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A4V04_RS02905 4690fd667f12a84af2af954a196ba433 296 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 246 265 4.1E-25 T 26-04-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4V04_RS02905 4690fd667f12a84af2af954a196ba433 296 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 156 168 4.1E-25 T 26-04-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4V04_RS02905 4690fd667f12a84af2af954a196ba433 296 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 92 108 4.1E-25 T 26-04-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4V04_RS02905 4690fd667f12a84af2af954a196ba433 296 ProSitePatterns PS00501 Signal peptidases I serine active site. 101 108 - T 26-04-2017 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 A4V04_RS02905 4690fd667f12a84af2af954a196ba433 296 ProSitePatterns PS00760 Signal peptidases I lysine active site. 158 170 - T 26-04-2017 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 A4V04_RS02905 4690fd667f12a84af2af954a196ba433 296 Gene3D G3DSA:2.10.109.10 246 290 3.0E-55 T 26-04-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain A4V04_RS02905 4690fd667f12a84af2af954a196ba433 296 Gene3D G3DSA:2.10.109.10 88 166 3.0E-55 T 26-04-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain A4V04_RS02905 4690fd667f12a84af2af954a196ba433 296 Pfam PF10502 Signal peptidase, peptidase S26 244 283 2.0E-5 T 26-04-2017 IPR019533 Peptidase S26 A4V04_RS02905 4690fd667f12a84af2af954a196ba433 296 Pfam PF00717 Peptidase S24-like 98 179 3.7E-23 T 26-04-2017 IPR019759 Peptidase S24/S26A/S26B A4V04_RS09765 22e6b982e06143da11dadd83d470cb11 439 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 6 436 7.2E-126 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS09765 22e6b982e06143da11dadd83d470cb11 439 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 6 370 7.9E-124 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS09765 22e6b982e06143da11dadd83d470cb11 439 PIRSF PIRSF004539 1 438 2.4E-141 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS01965 bb256450a702bcc1090ac65f15fade0b 489 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 35 482 7.0E-93 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS01965 bb256450a702bcc1090ac65f15fade0b 489 Gene3D G3DSA:3.50.50.60 428 488 2.2E-75 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS01965 bb256450a702bcc1090ac65f15fade0b 489 Gene3D G3DSA:3.50.50.60 27 263 2.2E-75 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS01965 bb256450a702bcc1090ac65f15fade0b 489 Gene3D G3DSA:3.90.700.10 286 422 4.0E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS01965 bb256450a702bcc1090ac65f15fade0b 489 SUPERFAMILY SSF56425 287 432 3.56E-24 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS01965 bb256450a702bcc1090ac65f15fade0b 489 Pfam PF00890 FAD binding domain 35 470 4.1E-57 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS01965 bb256450a702bcc1090ac65f15fade0b 489 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 35 57 9.5E-5 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS01965 bb256450a702bcc1090ac65f15fade0b 489 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 305 324 9.5E-5 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS01965 bb256450a702bcc1090ac65f15fade0b 489 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 139 147 9.5E-5 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS01965 bb256450a702bcc1090ac65f15fade0b 489 SUPERFAMILY SSF51905 30 269 1.63E-41 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS01965 bb256450a702bcc1090ac65f15fade0b 489 SUPERFAMILY SSF51905 431 488 1.63E-41 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12375 f89d5fe80c41f56e6a41c105dde09747 206 Pfam PF00857 Isochorismatase family 6 202 2.5E-30 T 26-04-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A4V04_RS12375 f89d5fe80c41f56e6a41c105dde09747 206 Gene3D G3DSA:3.40.50.850 3 204 5.4E-66 T 26-04-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A4V04_RS12375 f89d5fe80c41f56e6a41c105dde09747 206 SUPERFAMILY SSF52499 3 205 4.32E-47 T 26-04-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A4V04_RS07330 afa9f05eda7ac3da7a950eee39375ef9 137 SUPERFAMILY SSF143422 1 132 1.18E-41 T 26-04-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS07330 afa9f05eda7ac3da7a950eee39375ef9 137 Gene3D G3DSA:3.30.70.1290 2 132 1.1E-45 T 26-04-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS07330 afa9f05eda7ac3da7a950eee39375ef9 137 SMART SM01321 10 131 2.1E-37 T 26-04-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS07330 afa9f05eda7ac3da7a950eee39375ef9 137 Pfam PF01797 Transposase IS200 like 10 131 3.1E-38 T 26-04-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS09205 a57a69c21a7063d47a0196b6dbe8a4d8 706 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 13 210 6.9E-61 T 26-04-2017 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A4V04_RS09205 a57a69c21a7063d47a0196b6dbe8a4d8 706 Gene3D G3DSA:1.10.599.10 433 693 6.9E-45 T 26-04-2017 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A4V04_RS09205 a57a69c21a7063d47a0196b6dbe8a4d8 706 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 304 690 3.1E-44 T 26-04-2017 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A4V04_RS09205 a57a69c21a7063d47a0196b6dbe8a4d8 706 SUPERFAMILY SSF48310 303 703 2.49E-42 T 26-04-2017 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A4V04_RS09205 a57a69c21a7063d47a0196b6dbe8a4d8 706 SUPERFAMILY SSF56228 8 215 6.28E-55 T 26-04-2017 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A4V04_RS09205 a57a69c21a7063d47a0196b6dbe8a4d8 706 SMART SM00790 10 212 6.0E-71 T 26-04-2017 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A4V04_RS09205 a57a69c21a7063d47a0196b6dbe8a4d8 706 Gene3D G3DSA:3.60.9.10 8 214 2.8E-68 T 26-04-2017 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A4V04_RS03225 06d7d11d24a1655234f6c3dce1ec0438 284 Gene3D G3DSA:3.20.20.140 166 274 9.2E-37 T 26-04-2017 A4V04_RS03225 06d7d11d24a1655234f6c3dce1ec0438 284 Gene3D G3DSA:3.20.20.140 14 96 9.2E-37 T 26-04-2017 A4V04_RS03225 06d7d11d24a1655234f6c3dce1ec0438 284 Pfam PF02811 PHP domain 14 84 3.3E-7 T 26-04-2017 IPR004013 PHP domain GO:0003824 A4V04_RS03225 06d7d11d24a1655234f6c3dce1ec0438 284 SUPERFAMILY SSF89550 174 267 8.76E-42 T 26-04-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4V04_RS03225 06d7d11d24a1655234f6c3dce1ec0438 284 SUPERFAMILY SSF89550 14 91 8.76E-42 T 26-04-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4V04_RS03225 06d7d11d24a1655234f6c3dce1ec0438 284 SMART SM00481 13 78 3.3E-14 T 26-04-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 A4V04_RS09285 bbdf336df083cbe1685798df9b7f070b 431 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 1 332 2.6E-87 T 26-04-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4V04_RS09285 bbdf336df083cbe1685798df9b7f070b 431 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 2 333 34.813 T 26-04-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 A4V04_RS09285 bbdf336df083cbe1685798df9b7f070b 431 SUPERFAMILY SSF52374 4 332 8.19E-78 T 26-04-2017 A4V04_RS09285 bbdf336df083cbe1685798df9b7f070b 431 Gene3D G3DSA:1.10.240.10 208 300 3.4E-22 T 26-04-2017 A4V04_RS09285 bbdf336df083cbe1685798df9b7f070b 431 Gene3D G3DSA:3.40.50.620 2 207 2.0E-75 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS09285 bbdf336df083cbe1685798df9b7f070b 431 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 20 - T 26-04-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS09285 bbdf336df083cbe1685798df9b7f070b 431 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 5.3E-20 T 26-04-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4V04_RS09285 bbdf336df083cbe1685798df9b7f070b 431 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 150 171 5.3E-20 T 26-04-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4V04_RS09285 bbdf336df083cbe1685798df9b7f070b 431 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 202 212 5.3E-20 T 26-04-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4V04_RS09285 bbdf336df083cbe1685798df9b7f070b 431 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 5.3E-20 T 26-04-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4V04_RS09285 bbdf336df083cbe1685798df9b7f070b 431 Pfam PF00579 tRNA synthetases class I (W and Y) 3 279 2.8E-51 T 26-04-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS10060 8ec38f5aec3e588a59f0a815dca26b49 172 SMART SM00506 3 132 1.5E-46 T 26-04-2017 IPR002589 Macro domain A4V04_RS10060 8ec38f5aec3e588a59f0a815dca26b49 172 SUPERFAMILY SSF52949 3 164 2.02E-60 T 26-04-2017 A4V04_RS10060 8ec38f5aec3e588a59f0a815dca26b49 172 Pfam PF01661 Macro domain 20 132 3.5E-43 T 26-04-2017 IPR002589 Macro domain A4V04_RS10060 8ec38f5aec3e588a59f0a815dca26b49 172 Gene3D G3DSA:3.40.220.10 3 165 2.7E-65 T 26-04-2017 A4V04_RS08205 a81730daef5061d2343c78a42802e095 321 Gene3D G3DSA:1.10.10.10 4 86 1.9E-13 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS08205 a81730daef5061d2343c78a42802e095 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 67 1.1E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS08205 a81730daef5061d2343c78a42802e095 321 SUPERFAMILY SSF53850 89 302 2.71E-21 T 26-04-2017 A4V04_RS08205 a81730daef5061d2343c78a42802e095 321 Pfam PF03466 LysR substrate binding domain 101 290 4.5E-15 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS08205 a81730daef5061d2343c78a42802e095 321 Gene3D G3DSA:3.40.190.10 278 302 7.8E-13 T 26-04-2017 A4V04_RS08205 a81730daef5061d2343c78a42802e095 321 Gene3D G3DSA:3.40.190.10 91 171 7.8E-13 T 26-04-2017 A4V04_RS08205 a81730daef5061d2343c78a42802e095 321 SUPERFAMILY SSF46785 8 85 1.65E-10 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS08205 a81730daef5061d2343c78a42802e095 321 Gene3D G3DSA:3.40.190.10 172 271 9.1E-8 T 26-04-2017 A4V04_RS08165 3864a9eedee68e4cf270bda94fbaac8b 949 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 563 804 1.1E-59 T 26-04-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 A4V04_RS08165 3864a9eedee68e4cf270bda94fbaac8b 949 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 46 258 2.7E-58 T 26-04-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 A4V04_RS08165 3864a9eedee68e4cf270bda94fbaac8b 949 Gene3D G3DSA:3.30.460.10 651 810 1.1E-45 T 26-04-2017 A4V04_RS08165 3864a9eedee68e4cf270bda94fbaac8b 949 Gene3D G3DSA:3.30.460.10 100 285 2.6E-50 T 26-04-2017 A4V04_RS08165 3864a9eedee68e4cf270bda94fbaac8b 949 SUPERFAMILY SSF81593 287 440 5.96E-38 T 26-04-2017 A4V04_RS08165 3864a9eedee68e4cf270bda94fbaac8b 949 SUPERFAMILY SSF81301 534 814 1.85E-68 T 26-04-2017 A4V04_RS08165 3864a9eedee68e4cf270bda94fbaac8b 949 Pfam PF08335 GlnD PII-uridylyltransferase 827 914 1.0E-7 T 26-04-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 A4V04_RS08165 3864a9eedee68e4cf270bda94fbaac8b 949 Pfam PF08335 GlnD PII-uridylyltransferase 299 439 5.4E-40 T 26-04-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 A4V04_RS08165 3864a9eedee68e4cf270bda94fbaac8b 949 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 13 946 17.687 T 26-04-2017 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 A4V04_RS08165 3864a9eedee68e4cf270bda94fbaac8b 949 SUPERFAMILY SSF81593 814 943 4.55E-29 T 26-04-2017 A4V04_RS08165 3864a9eedee68e4cf270bda94fbaac8b 949 SUPERFAMILY SSF81301 50 285 9.81E-58 T 26-04-2017 A4V04_RS06275 d35250073185a2a66c05cd4f48ba0604 104 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 4 80 3.3E-25 T 26-04-2017 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 A4V04_RS06275 d35250073185a2a66c05cd4f48ba0604 104 Gene3D G3DSA:1.10.260.40 1 84 5.6E-28 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS06275 d35250073185a2a66c05cd4f48ba0604 104 SUPERFAMILY SSF47413 8 84 3.9E-22 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS06275 d35250073185a2a66c05cd4f48ba0604 104 SMART SM00530 12 67 4.3E-8 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS06275 d35250073185a2a66c05cd4f48ba0604 104 Pfam PF01381 Helix-turn-helix 16 66 2.9E-9 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 5.1E-53 T 26-04-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 463 491 5.1E-53 T 26-04-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 5.1E-53 T 26-04-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 519 5.1E-53 T 26-04-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 533 545 5.1E-53 T 26-04-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 Gene3D G3DSA:3.30.930.10 241 529 1.5E-120 T 26-04-2017 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 SMART SM00863 169 218 9.9E-24 T 26-04-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 SUPERFAMILY SSF52954 528 636 4.68E-30 T 26-04-2017 IPR004154 Anticodon-binding A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 Gene3D G3DSA:3.30.54.20 130 186 3.2E-24 T 26-04-2017 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 317 528 2.6E-44 T 26-04-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 SUPERFAMILY SSF81271 2 61 8.28E-17 T 26-04-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 Pfam PF02824 TGS domain 2 61 3.0E-13 T 26-04-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 633 34.074 T 26-04-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 Pfam PF03129 Anticodon binding domain 540 629 1.8E-18 T 26-04-2017 IPR004154 Anticodon-binding A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 SUPERFAMILY SSF55186 63 240 7.98E-68 T 26-04-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 3.2E-14 T 26-04-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 Gene3D G3DSA:3.10.20.30 1 64 3.5E-25 T 26-04-2017 IPR012675 Beta-grasp domain A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 SUPERFAMILY SSF55681 242 525 2.87E-98 T 26-04-2017 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 630 3.2E-219 T 26-04-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 Gene3D G3DSA:3.30.980.10 66 129 6.9E-41 T 26-04-2017 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 Gene3D G3DSA:3.30.980.10 187 223 6.9E-41 T 26-04-2017 A4V04_RS00195 0808e39b9f55d7bbf94cac3c8dab0e3e 640 Gene3D G3DSA:3.40.50.800 531 635 2.5E-33 T 26-04-2017 IPR004154 Anticodon-binding A4V04_RS12515 d45df505114e16673ff7b29706fb191a 352 Pfam PF00005 ABC transporter 24 171 3.0E-36 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS12515 d45df505114e16673ff7b29706fb191a 352 SMART SM00382 32 228 1.0E-13 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS12515 d45df505114e16673ff7b29706fb191a 352 Gene3D G3DSA:3.30.70.260 239 351 1.1E-26 T 26-04-2017 A4V04_RS12515 d45df505114e16673ff7b29706fb191a 352 SUPERFAMILY SSF52540 1 241 2.3E-83 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12515 d45df505114e16673ff7b29706fb191a 352 SUPERFAMILY SSF55021 274 351 2.29E-20 T 26-04-2017 A4V04_RS12515 d45df505114e16673ff7b29706fb191a 352 Pfam PF09383 NIL domain 276 347 3.9E-20 T 26-04-2017 IPR018449 NIL domain A4V04_RS12515 d45df505114e16673ff7b29706fb191a 352 Gene3D G3DSA:3.40.50.300 1 238 1.5E-86 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12515 d45df505114e16673ff7b29706fb191a 352 SMART SM00930 274 348 1.3E-23 T 26-04-2017 IPR018449 NIL domain A4V04_RS12515 d45df505114e16673ff7b29706fb191a 352 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS05700 d791fb7985d9704cf3e1ba0f589fb34b 603 SUPERFAMILY SSF53098 268 517 2.65E-8 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS05700 d791fb7985d9704cf3e1ba0f589fb34b 603 Pfam PF01609 Transposase DDE domain 204 504 1.2E-10 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS11565 d791fb7985d9704cf3e1ba0f589fb34b 603 SUPERFAMILY SSF53098 268 517 2.65E-8 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS11565 d791fb7985d9704cf3e1ba0f589fb34b 603 Pfam PF01609 Transposase DDE domain 204 504 1.2E-10 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS13070 d791fb7985d9704cf3e1ba0f589fb34b 603 SUPERFAMILY SSF53098 268 517 2.65E-8 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS13070 d791fb7985d9704cf3e1ba0f589fb34b 603 Pfam PF01609 Transposase DDE domain 204 504 1.2E-10 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS07570 d791fb7985d9704cf3e1ba0f589fb34b 603 SUPERFAMILY SSF53098 268 517 2.65E-8 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS07570 d791fb7985d9704cf3e1ba0f589fb34b 603 Pfam PF01609 Transposase DDE domain 204 504 1.2E-10 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS02205 d791fb7985d9704cf3e1ba0f589fb34b 603 SUPERFAMILY SSF53098 268 517 2.65E-8 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS02205 d791fb7985d9704cf3e1ba0f589fb34b 603 Pfam PF01609 Transposase DDE domain 204 504 1.2E-10 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS11570 7b3b94644bba7592191a2317138b4e51 334 Gene3D G3DSA:3.90.1150.10 260 331 1.3E-12 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS11570 7b3b94644bba7592191a2317138b4e51 334 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 11 331 2.7E-104 T 26-04-2017 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 A4V04_RS11570 7b3b94644bba7592191a2317138b4e51 334 SUPERFAMILY SSF53383 9 331 2.1E-80 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS11570 7b3b94644bba7592191a2317138b4e51 334 Gene3D G3DSA:3.40.640.10 53 259 1.4E-50 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS11570 7b3b94644bba7592191a2317138b4e51 334 Pfam PF00155 Aminotransferase class I and II 38 316 1.2E-30 T 26-04-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4V04_RS02135 356b3800465e1052568cf1ef48346618 279 Pfam PF01380 SIS domain 124 234 3.6E-14 T 26-04-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4V04_RS02135 356b3800465e1052568cf1ef48346618 279 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 75 1.6E-15 T 26-04-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A4V04_RS02135 356b3800465e1052568cf1ef48346618 279 SUPERFAMILY SSF46689 3 78 9.32E-19 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS02135 356b3800465e1052568cf1ef48346618 279 SUPERFAMILY SSF53697 97 236 6.23E-16 T 26-04-2017 A4V04_RS02135 356b3800465e1052568cf1ef48346618 279 Gene3D G3DSA:1.10.10.10 2 64 1.1E-23 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02135 356b3800465e1052568cf1ef48346618 279 Gene3D G3DSA:3.40.50.10490 65 233 3.0E-16 T 26-04-2017 A4V04_RS12765 877ce8572f89e7bc9de0d264d4db49d1 289 Pfam PF13286 Phosphohydrolase-associated domain 192 279 2.3E-24 T 26-04-2017 IPR026875 Phosphohydrolase-associated domain A4V04_RS12765 877ce8572f89e7bc9de0d264d4db49d1 289 SUPERFAMILY SSF109604 75 284 3.45E-25 T 26-04-2017 A4V04_RS12765 877ce8572f89e7bc9de0d264d4db49d1 289 Gene3D G3DSA:1.10.3210.10 82 127 1.0E-24 T 26-04-2017 IPR006674 HD domain A4V04_RS12765 877ce8572f89e7bc9de0d264d4db49d1 289 Gene3D G3DSA:1.10.3210.10 186 285 1.0E-24 T 26-04-2017 IPR006674 HD domain A4V04_RS10615 4b072e6319bc8bf1693a078ca1635db9 201 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 31 191 1.5E-10 T 26-04-2017 IPR005586 ABC-type transport auxiliary lipoprotein component A4V04_RS10615 4b072e6319bc8bf1693a078ca1635db9 201 Gene3D G3DSA:3.40.50.10610 17 195 1.1E-21 T 26-04-2017 IPR005586 ABC-type transport auxiliary lipoprotein component A4V04_RS10615 4b072e6319bc8bf1693a078ca1635db9 201 SUPERFAMILY SSF159594 27 196 6.28E-23 T 26-04-2017 A4V04_RS08790 a1abcf78ecd5a97219fe4b728fb11956 146 Pfam PF11026 Protein of unknown function (DUF2721) 11 135 2.3E-29 T 26-04-2017 IPR021279 Protein of unknown function DUF2721 A4V04_RS04220 2b323cd119d465d03bdff7186c258522 112 SUPERFAMILY SSF54913 1 112 6.04E-43 T 26-04-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta A4V04_RS04220 2b323cd119d465d03bdff7186c258522 112 SMART SM00938 4 105 3.3E-62 T 26-04-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4V04_RS04220 2b323cd119d465d03bdff7186c258522 112 PIRSF PIRSF039144 1 112 7.1E-50 T 26-04-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4V04_RS04220 2b323cd119d465d03bdff7186c258522 112 Gene3D G3DSA:3.30.70.120 1 112 8.7E-48 T 26-04-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A4V04_RS04220 2b323cd119d465d03bdff7186c258522 112 PRINTS PR00340 P-II protein signature 23 41 7.8E-39 T 26-04-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4V04_RS04220 2b323cd119d465d03bdff7186c258522 112 PRINTS PR00340 P-II protein signature 83 103 7.8E-39 T 26-04-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4V04_RS04220 2b323cd119d465d03bdff7186c258522 112 PRINTS PR00340 P-II protein signature 52 75 7.8E-39 T 26-04-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4V04_RS04220 2b323cd119d465d03bdff7186c258522 112 PRINTS PR00340 P-II protein signature 2 17 7.8E-39 T 26-04-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4V04_RS04220 2b323cd119d465d03bdff7186c258522 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 26-04-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 A4V04_RS04220 2b323cd119d465d03bdff7186c258522 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.8E-40 T 26-04-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4V04_RS04220 2b323cd119d465d03bdff7186c258522 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 26-04-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 SMART SM01086 652 742 1.1E-30 T 26-04-2017 IPR019489 Clp ATPase, C-terminal A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 561 579 1.7E-38 T 26-04-2017 IPR001270 ClpA/B family GO:0005524 A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 594 608 1.7E-38 T 26-04-2017 IPR001270 ClpA/B family GO:0005524 A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 490 508 1.7E-38 T 26-04-2017 IPR001270 ClpA/B family GO:0005524 A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 532 550 1.7E-38 T 26-04-2017 IPR001270 ClpA/B family GO:0005524 A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 Pfam PF07724 AAA domain (Cdc48 subfamily) 485 646 9.5E-46 T 26-04-2017 IPR003959 ATPase, AAA-type, core GO:0005524 A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 SMART SM00382 486 635 1.5E-10 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 SMART SM00382 206 350 4.4E-10 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 Gene3D G3DSA:1.10.8.60 663 741 7.6E-27 T 26-04-2017 A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 652 732 1.4E-22 T 26-04-2017 IPR019489 Clp ATPase, C-terminal A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 Gene3D G3DSA:1.10.1780.10 5 143 1.3E-21 T 26-04-2017 IPR004176 Clp, N-terminal GO:0019538 A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 Gene3D G3DSA:3.40.50.300 169 350 2.2E-40 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 211 343 1.3E-12 T 26-04-2017 IPR003959 ATPase, AAA-type, core GO:0005524 A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 SUPERFAMILY SSF52540 436 730 1.88E-74 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 Gene3D G3DSA:1.10.8.60 351 426 1.9E-28 T 26-04-2017 A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 SUPERFAMILY SSF52540 168 416 2.22E-65 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 SUPERFAMILY SSF81923 4 140 7.85E-26 T 26-04-2017 IPR004176 Clp, N-terminal GO:0019538 A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 105 144 0.16 T 26-04-2017 IPR004176 Clp, N-terminal GO:0019538 A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 20 64 0.004 T 26-04-2017 IPR004176 Clp, N-terminal GO:0019538 A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 517 535 - T 26-04-2017 IPR028299 ClpA/B, conserved site 2 A4V04_RS00805 d5b8a9a9dae2d6b24d3fcfe4bca84635 770 Gene3D G3DSA:3.40.50.300 441 662 6.3E-55 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10210 7647160890e7dd91282f762c0b39bdcc 589 SMART SM00028 509 542 17.0 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS10210 7647160890e7dd91282f762c0b39bdcc 589 SMART SM00028 197 230 130.0 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS10210 7647160890e7dd91282f762c0b39bdcc 589 SMART SM00028 543 575 290.0 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS10210 7647160890e7dd91282f762c0b39bdcc 589 SMART SM00028 474 508 51.0 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS10210 7647160890e7dd91282f762c0b39bdcc 589 SMART SM00028 440 473 9.6 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS10210 7647160890e7dd91282f762c0b39bdcc 589 SMART SM00028 370 400 120.0 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS10210 7647160890e7dd91282f762c0b39bdcc 589 Pfam PF14559 Tetratricopeptide repeat 520 580 2.9E-6 T 26-04-2017 A4V04_RS10210 7647160890e7dd91282f762c0b39bdcc 589 SUPERFAMILY SSF48452 423 575 1.04E-24 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS10210 7647160890e7dd91282f762c0b39bdcc 589 Pfam PF13431 Tetratricopeptide repeat 463 494 1.3E-5 T 26-04-2017 A4V04_RS10210 7647160890e7dd91282f762c0b39bdcc 589 Gene3D G3DSA:1.25.40.10 79 291 4.8E-9 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS10210 7647160890e7dd91282f762c0b39bdcc 589 Gene3D G3DSA:1.25.40.10 292 577 2.3E-33 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS10210 7647160890e7dd91282f762c0b39bdcc 589 SUPERFAMILY SSF48452 176 330 6.07E-8 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS01060 c5b0da0e78de9c05e1c104d906a1d837 297 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 11 292 1.9E-85 T 26-04-2017 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A4V04_RS01060 c5b0da0e78de9c05e1c104d906a1d837 297 SUPERFAMILY SSF56104 5 293 6.21E-106 T 26-04-2017 A4V04_RS01060 c5b0da0e78de9c05e1c104d906a1d837 297 Pfam PF01259 SAICAR synthetase 14 268 6.2E-107 T 26-04-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS01060 c5b0da0e78de9c05e1c104d906a1d837 297 ProSitePatterns PS01058 SAICAR synthetase signature 2. 204 212 - T 26-04-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS01060 c5b0da0e78de9c05e1c104d906a1d837 297 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 12 292 26.794 T 26-04-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS01060 c5b0da0e78de9c05e1c104d906a1d837 297 ProSitePatterns PS01057 SAICAR synthetase signature 1. 105 119 - T 26-04-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS01060 c5b0da0e78de9c05e1c104d906a1d837 297 Gene3D G3DSA:3.30.200.20 4 116 1.6E-42 T 26-04-2017 A4V04_RS01060 c5b0da0e78de9c05e1c104d906a1d837 297 Gene3D G3DSA:3.30.470.20 117 247 1.1E-58 T 26-04-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 SUPERFAMILY SSF50465 304 394 9.21E-36 T 26-04-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.4E-24 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.4E-24 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.4E-24 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.4E-24 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.4E-24 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 Gene3D G3DSA:3.40.50.300 3 211 7.9E-70 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 9.8E-18 T 26-04-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 7.0E-16 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 SUPERFAMILY SSF50447 207 303 5.3E-31 T 26-04-2017 IPR009000 Translation protein, beta-barrel domain A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 26-04-2017 IPR031157 Tr-type G domain, conserved site A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 3.5E-34 T 26-04-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 Gene3D G3DSA:2.40.30.10 212 300 5.6E-38 T 26-04-2017 A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 394 2.8E-230 T 26-04-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 4.8E-58 T 26-04-2017 A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 Gene3D G3DSA:2.40.30.10 302 394 1.2E-47 T 26-04-2017 A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.817 T 26-04-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS11175 8b150fd82804d836212da1017822a64c 396 SUPERFAMILY SSF52540 9 228 8.3E-61 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 SUPERFAMILY SSF50465 304 394 9.21E-36 T 26-04-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.4E-24 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.4E-24 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.4E-24 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.4E-24 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.4E-24 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 Gene3D G3DSA:3.40.50.300 3 211 7.9E-70 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 9.8E-18 T 26-04-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 7.0E-16 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 SUPERFAMILY SSF50447 207 303 5.3E-31 T 26-04-2017 IPR009000 Translation protein, beta-barrel domain A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 26-04-2017 IPR031157 Tr-type G domain, conserved site A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 3.5E-34 T 26-04-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 Gene3D G3DSA:2.40.30.10 212 300 5.6E-38 T 26-04-2017 A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 394 2.8E-230 T 26-04-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 4.8E-58 T 26-04-2017 A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 Gene3D G3DSA:2.40.30.10 302 394 1.2E-47 T 26-04-2017 A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.817 T 26-04-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4V04_RS11110 8b150fd82804d836212da1017822a64c 396 SUPERFAMILY SSF52540 9 228 8.3E-61 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11995 021c0f046543c705487aa0ea94a77506 440 Hamap MF_02033 Cell division protein FtsA [ftsA]. 5 440 22.376 T 26-04-2017 IPR020823 Cell division protein FtsA GO:0007049 A4V04_RS11995 021c0f046543c705487aa0ea94a77506 440 SUPERFAMILY SSF53067 200 353 5.94E-25 T 26-04-2017 A4V04_RS11995 021c0f046543c705487aa0ea94a77506 440 Gene3D G3DSA:3.90.640.10 236 301 1.0E-4 T 26-04-2017 A4V04_RS11995 021c0f046543c705487aa0ea94a77506 440 Gene3D G3DSA:3.30.420.40 198 235 9.9E-23 T 26-04-2017 A4V04_RS11995 021c0f046543c705487aa0ea94a77506 440 Gene3D G3DSA:3.30.420.40 302 351 9.9E-23 T 26-04-2017 A4V04_RS11995 021c0f046543c705487aa0ea94a77506 440 Gene3D G3DSA:3.30.420.40 6 138 1.3E-23 T 26-04-2017 A4V04_RS11995 021c0f046543c705487aa0ea94a77506 440 SUPERFAMILY SSF53067 7 212 6.17E-37 T 26-04-2017 A4V04_RS11995 021c0f046543c705487aa0ea94a77506 440 Pfam PF14450 Cell division protein FtsA 10 190 3.9E-9 T 26-04-2017 A4V04_RS11995 021c0f046543c705487aa0ea94a77506 440 Pfam PF14450 Cell division protein FtsA 208 403 1.8E-13 T 26-04-2017 A4V04_RS11995 021c0f046543c705487aa0ea94a77506 440 Pfam PF02491 SHS2 domain inserted in FTSA 84 161 3.4E-16 T 26-04-2017 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 A4V04_RS11995 021c0f046543c705487aa0ea94a77506 440 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 352 2.8E-87 T 26-04-2017 IPR020823 Cell division protein FtsA GO:0007049 A4V04_RS11995 021c0f046543c705487aa0ea94a77506 440 SMART SM00842 9 197 4.8E-49 T 26-04-2017 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 A4V04_RS11995 021c0f046543c705487aa0ea94a77506 440 PIRSF PIRSF003101 1 436 2.3E-94 T 26-04-2017 IPR020823 Cell division protein FtsA GO:0007049 A4V04_RS10095 6a4468f91732879b24194dc838e10926 261 Gene3D G3DSA:2.170.130.10 27 159 1.6E-32 T 26-04-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 A4V04_RS10095 6a4468f91732879b24194dc838e10926 261 SUPERFAMILY SSF56935 26 246 4.12E-40 T 26-04-2017 A4V04_RS10095 6a4468f91732879b24194dc838e10926 261 Gene3D G3DSA:2.40.170.20 160 247 2.5E-4 T 26-04-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A4V04_RS10095 6a4468f91732879b24194dc838e10926 261 Pfam PF07715 TonB-dependent Receptor Plug Domain 50 156 4.9E-22 T 26-04-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 A4V04_RS00930 819420f46c296acba8260c9db7894b30 214 Pfam PF01713 Smr domain 131 211 5.5E-22 T 26-04-2017 IPR002625 Smr domain A4V04_RS00930 819420f46c296acba8260c9db7894b30 214 SUPERFAMILY SSF160443 130 211 5.75E-17 T 26-04-2017 IPR002625 Smr domain A4V04_RS00930 819420f46c296acba8260c9db7894b30 214 SMART SM00463 128 212 2.9E-15 T 26-04-2017 IPR002625 Smr domain A4V04_RS10365 549f7f4359d48a834fc1c15b5c7df52c 630 SUPERFAMILY SSF51905 573 630 5.0E-55 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10365 549f7f4359d48a834fc1c15b5c7df52c 630 SUPERFAMILY SSF51905 125 184 5.0E-55 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10365 549f7f4359d48a834fc1c15b5c7df52c 630 SUPERFAMILY SSF51905 228 431 5.0E-55 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10365 549f7f4359d48a834fc1c15b5c7df52c 630 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 235 626 1.2E-87 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS10365 549f7f4359d48a834fc1c15b5c7df52c 630 Gene3D G3DSA:3.90.700.10 437 561 4.6E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10365 549f7f4359d48a834fc1c15b5c7df52c 630 SUPERFAMILY SSF56425 437 574 1.92E-28 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10365 549f7f4359d48a834fc1c15b5c7df52c 630 Pfam PF00890 FAD binding domain 133 214 2.6E-16 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10365 549f7f4359d48a834fc1c15b5c7df52c 630 Pfam PF00890 FAD binding domain 235 613 6.2E-59 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10365 549f7f4359d48a834fc1c15b5c7df52c 630 SMART SM00900 33 107 6.3E-16 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS10365 549f7f4359d48a834fc1c15b5c7df52c 630 Gene3D G3DSA:3.50.50.60 230 414 7.2E-91 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10365 549f7f4359d48a834fc1c15b5c7df52c 630 Gene3D G3DSA:3.50.50.60 127 186 7.2E-91 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10365 549f7f4359d48a834fc1c15b5c7df52c 630 Gene3D G3DSA:3.50.50.60 570 630 7.2E-91 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10365 549f7f4359d48a834fc1c15b5c7df52c 630 Pfam PF04205 FMN-binding domain 33 105 9.7E-14 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS09410 686ba022c2c8237aad311fd952c98081 491 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 54 387 8.7E-93 T 26-04-2017 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 A4V04_RS09410 686ba022c2c8237aad311fd952c98081 491 SUPERFAMILY SSF50156 92 183 1.45E-17 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS09410 686ba022c2c8237aad311fd952c98081 491 Gene3D G3DSA:2.30.42.10 106 182 1.9E-26 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS09410 686ba022c2c8237aad311fd952c98081 491 Pfam PF13180 PDZ domain 100 180 5.6E-14 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS09410 686ba022c2c8237aad311fd952c98081 491 Gene3D G3DSA:3.90.226.10 183 385 3.6E-66 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS09410 686ba022c2c8237aad311fd952c98081 491 Gene3D G3DSA:3.90.226.10 446 474 3.6E-66 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS09410 686ba022c2c8237aad311fd952c98081 491 SMART SM00245 173 383 9.5E-60 T 26-04-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A4V04_RS09410 686ba022c2c8237aad311fd952c98081 491 SMART SM00228 100 171 1.4E-14 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS09410 686ba022c2c8237aad311fd952c98081 491 Gene3D G3DSA:3.30.750.44 58 105 2.4E-9 T 26-04-2017 A4V04_RS09410 686ba022c2c8237aad311fd952c98081 491 SUPERFAMILY SSF52096 192 391 8.45E-71 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS09410 686ba022c2c8237aad311fd952c98081 491 SUPERFAMILY SSF52096 37 118 8.45E-71 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS09410 686ba022c2c8237aad311fd952c98081 491 Pfam PF03572 Peptidase family S41 199 382 5.0E-51 T 26-04-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A4V04_RS06970 663e3a8b60860366b54931d69bade69f 66 SMART SM01409 8 59 6.6E-12 T 26-04-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A4V04_RS06970 663e3a8b60860366b54931d69bade69f 66 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 55 6.6E-18 T 26-04-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS06970 663e3a8b60860366b54931d69bade69f 66 Gene3D G3DSA:3.90.940.10 1 59 1.1E-9 T 26-04-2017 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A4V04_RS06970 663e3a8b60860366b54931d69bade69f 66 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 60 15.195 T 26-04-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS06970 663e3a8b60860366b54931d69bade69f 66 Pfam PF01192 RNA polymerase Rpb6 8 57 2.8E-13 T 26-04-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A4V04_RS06970 663e3a8b60860366b54931d69bade69f 66 SUPERFAMILY SSF63562 1 64 3.14E-18 T 26-04-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A4V04_RS00260 f2eb7aa18a54386e3932591f7e574a34 398 SUPERFAMILY SSF47413 24 87 2.4E-6 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS00260 f2eb7aa18a54386e3932591f7e574a34 398 Gene3D G3DSA:1.10.260.40 24 91 4.5E-8 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS00260 f2eb7aa18a54386e3932591f7e574a34 398 Pfam PF13464 Domain of unknown function (DUF4115) 323 387 2.7E-14 T 26-04-2017 IPR025194 Domain of unknown function DUF4115 A4V04_RS00260 f2eb7aa18a54386e3932591f7e574a34 398 Pfam PF13413 Helix-turn-helix domain 29 88 4.1E-19 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS03765 882ef2e01cb2ebf10cb493faabceb835 656 Pfam PF01757 Acyltransferase family 13 335 2.4E-24 T 26-04-2017 IPR002656 Acyltransferase 3 GO:0016747 A4V04_RS03765 882ef2e01cb2ebf10cb493faabceb835 656 Gene3D G3DSA:3.40.50.1110 526 655 3.1E-4 T 26-04-2017 IPR013830 SGNH hydrolase-type esterase domain A4V04_RS03765 882ef2e01cb2ebf10cb493faabceb835 656 SUPERFAMILY SSF52266 416 654 5.5E-5 T 26-04-2017 IPR013830 SGNH hydrolase-type esterase domain A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 Gene3D G3DSA:3.40.120.10 250 361 3.5E-39 T 26-04-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 SUPERFAMILY SSF55957 365 458 5.58E-21 T 26-04-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 381 449 3.4E-12 T 26-04-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 247 3.3E-25 T 26-04-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 3.3E-25 T 26-04-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 203 216 3.3E-25 T 26-04-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 169 188 3.3E-25 T 26-04-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 133 5.1E-33 T 26-04-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 155 252 9.8E-24 T 26-04-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 Gene3D G3DSA:3.40.120.10 5 138 5.1E-34 T 26-04-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 Gene3D G3DSA:3.40.120.10 171 248 1.9E-30 T 26-04-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 SUPERFAMILY SSF53738 5 140 9.42E-39 T 26-04-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 SUPERFAMILY SSF53738 257 352 1.18E-29 T 26-04-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 SUPERFAMILY SSF53738 153 254 1.73E-29 T 26-04-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 353 7.9E-21 T 26-04-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 97 106 - T 26-04-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS08745 ce82cbe3555e5b94707c1e729661636f 460 Gene3D G3DSA:3.30.310.50 368 457 8.8E-28 T 26-04-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS06615 fca3b957a6797a6550afa456fbb8f7f5 309 Pfam PF02661 Fic/DOC family 153 245 2.4E-8 T 26-04-2017 IPR003812 Fido domain A4V04_RS06615 fca3b957a6797a6550afa456fbb8f7f5 309 Gene3D G3DSA:1.10.3290.10 102 289 8.2E-20 T 26-04-2017 IPR003812 Fido domain A4V04_RS06615 fca3b957a6797a6550afa456fbb8f7f5 309 SUPERFAMILY SSF140931 128 292 1.29E-15 T 26-04-2017 IPR003812 Fido domain A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 SUPERFAMILY SSF54980 294 370 7.19E-17 T 26-04-2017 IPR009022 Elongation factor G, III-V domain A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 SUPERFAMILY SSF54980 399 493 2.78E-27 T 26-04-2017 IPR009022 Elongation factor G, III-V domain A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 SMART SM00838 398 485 0.0011 T 26-04-2017 IPR000640 Translation elongation factor EFG, V domain A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 Gene3D G3DSA:3.40.50.300 2 192 3.3E-61 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 SUPERFAMILY SSF52540 2 205 1.37E-57 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 174 1.3E-20 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 Pfam PF00679 Elongation factor G C-terminus 399 484 4.5E-23 T 26-04-2017 IPR000640 Translation elongation factor EFG, V domain A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 2.3E-14 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 PRINTS PR00315 GTP-binding elongation factor signature 6 19 2.3E-14 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 2.3E-14 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 2.3E-14 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 PRINTS PR00315 GTP-binding elongation factor signature 49 57 2.3E-14 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 TIGRFAM TIGR01393 lepA: elongation factor 4 2 595 1.4E-297 T 26-04-2017 IPR006297 Elongation factor 4 GO:0005525 A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 Gene3D G3DSA:3.30.70.240 401 489 8.2E-23 T 26-04-2017 IPR000640 Translation elongation factor EFG, V domain A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 Pfam PF00009 Elongation factor Tu GTP binding domain 3 181 2.1E-53 T 26-04-2017 A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 Pfam PF03144 Elongation factor Tu domain 2 205 275 1.6E-11 T 26-04-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 26-04-2017 IPR031157 Tr-type G domain, conserved site A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 Gene3D G3DSA:3.30.70.870 292 369 8.6E-24 T 26-04-2017 A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 Hamap MF_00071 Elongation factor 4 [lepA]. 1 597 299.798 T 26-04-2017 IPR006297 Elongation factor 4 GO:0005525 A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 Gene3D G3DSA:2.40.30.10 193 290 1.1E-26 T 26-04-2017 A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 Pfam PF06421 GTP-binding protein LepA C-terminus 487 593 1.2E-47 T 26-04-2017 IPR013842 GTP-binding protein LepA, C-terminal A4V04_RS02900 aeb3f235b605209289aed93af724e6e8 597 SUPERFAMILY SSF50447 165 288 1.62E-31 T 26-04-2017 IPR009000 Translation protein, beta-barrel domain A4V04_RS09220 24257bb5511107dbbb89b64056f699d0 499 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 47 66 4.0E-7 T 26-04-2017 A4V04_RS09220 24257bb5511107dbbb89b64056f699d0 499 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 442 464 4.0E-7 T 26-04-2017 A4V04_RS09220 24257bb5511107dbbb89b64056f699d0 499 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 46 490 8.2E-111 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS09220 24257bb5511107dbbb89b64056f699d0 499 SUPERFAMILY SSF51905 437 494 2.3E-58 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS09220 24257bb5511107dbbb89b64056f699d0 499 SUPERFAMILY SSF51905 31 312 2.3E-58 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS09220 24257bb5511107dbbb89b64056f699d0 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 46 68 7.9E-8 T 26-04-2017 A4V04_RS09220 24257bb5511107dbbb89b64056f699d0 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 478 493 7.9E-8 T 26-04-2017 A4V04_RS09220 24257bb5511107dbbb89b64056f699d0 499 Pfam PF00890 FAD binding domain 46 478 1.7E-74 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS09220 24257bb5511107dbbb89b64056f699d0 499 SUPERFAMILY SSF56425 291 438 5.02E-28 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS09220 24257bb5511107dbbb89b64056f699d0 499 Gene3D G3DSA:3.90.700.10 290 425 2.6E-27 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS09220 24257bb5511107dbbb89b64056f699d0 499 Gene3D G3DSA:3.50.50.60 33 279 2.0E-93 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS09220 24257bb5511107dbbb89b64056f699d0 499 Gene3D G3DSA:3.50.50.60 434 495 2.0E-93 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04510 6a93209d1045c97377d3eb40206eadd1 132 Pfam PF13411 MerR HTH family regulatory protein 1 68 3.0E-17 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS04510 6a93209d1045c97377d3eb40206eadd1 132 Gene3D G3DSA:1.10.1660.10 56 132 1.8E-16 T 26-04-2017 A4V04_RS04510 6a93209d1045c97377d3eb40206eadd1 132 SMART SM00422 1 70 2.5E-26 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS04510 6a93209d1045c97377d3eb40206eadd1 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.2E-6 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS04510 6a93209d1045c97377d3eb40206eadd1 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.2E-6 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS04510 6a93209d1045c97377d3eb40206eadd1 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.2E-6 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS04510 6a93209d1045c97377d3eb40206eadd1 132 Gene3D G3DSA:1.10.1660.10 1 55 4.1E-24 T 26-04-2017 A4V04_RS04510 6a93209d1045c97377d3eb40206eadd1 132 SUPERFAMILY SSF46955 1 119 2.97E-31 T 26-04-2017 IPR009061 Putative DNA-binding domain A4V04_RS10000 6b99988e36cef7743eb8f96ff15f2c71 531 Pfam PF09820 Predicted AAA-ATPase 10 287 3.6E-75 T 26-04-2017 IPR018631 AAA-ATPase-like domain A4V04_RS10000 6b99988e36cef7743eb8f96ff15f2c71 531 SUPERFAMILY SSF52540 34 267 8.5E-5 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10000 6b99988e36cef7743eb8f96ff15f2c71 531 Pfam PF08011 PD-(D/E)XK nuclease superfamily 431 525 2.9E-12 T 26-04-2017 IPR012547 PD-(D/E)XK nuclease superfamily 9 A4V04_RS00175 c5cc5fc0eaa180a3f83887043bfba8a7 338 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 38 337 7.4E-97 T 26-04-2017 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A4V04_RS00175 c5cc5fc0eaa180a3f83887043bfba8a7 338 Gene3D G3DSA:3.30.930.10 9 338 4.1E-124 T 26-04-2017 A4V04_RS00175 c5cc5fc0eaa180a3f83887043bfba8a7 338 Pfam PF01409 tRNA synthetases class II core domain (F) 92 337 5.0E-93 T 26-04-2017 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A4V04_RS00175 c5cc5fc0eaa180a3f83887043bfba8a7 338 SUPERFAMILY SSF46589 14 99 1.67E-19 T 26-04-2017 IPR010978 tRNA-binding arm GO:0000166 A4V04_RS00175 c5cc5fc0eaa180a3f83887043bfba8a7 338 SUPERFAMILY SSF55681 92 338 1.32E-74 T 26-04-2017 A4V04_RS00175 c5cc5fc0eaa180a3f83887043bfba8a7 338 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 87 4.6E-21 T 26-04-2017 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A4V04_RS00175 c5cc5fc0eaa180a3f83887043bfba8a7 338 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 337 45.754 T 26-04-2017 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 A4V04_RS02375 33cf04aac11e4841542c78a7529f65f1 598 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 536 3.9E-5 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS02375 33cf04aac11e4841542c78a7529f65f1 598 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 569 3.9E-5 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS02375 33cf04aac11e4841542c78a7529f65f1 598 SUPERFAMILY SSF53850 106 249 9.9E-6 T 26-04-2017 A4V04_RS02375 33cf04aac11e4841542c78a7529f65f1 598 Gene3D G3DSA:1.10.287.130 375 429 1.8E-4 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS02375 33cf04aac11e4841542c78a7529f65f1 598 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 484 573 2.1E-10 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS02375 33cf04aac11e4841542c78a7529f65f1 598 Gene3D G3DSA:3.30.565.10 430 591 6.2E-25 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS02375 33cf04aac11e4841542c78a7529f65f1 598 SUPERFAMILY SSF55874 435 589 3.14E-24 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS02375 33cf04aac11e4841542c78a7529f65f1 598 Gene3D G3DSA:3.40.190.10 120 225 8.7E-5 T 26-04-2017 A4V04_RS02375 33cf04aac11e4841542c78a7529f65f1 598 SUPERFAMILY SSF47384 373 440 2.16E-6 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS02375 33cf04aac11e4841542c78a7529f65f1 598 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 95 260 1.0E-12 T 26-04-2017 A4V04_RS02375 33cf04aac11e4841542c78a7529f65f1 598 SMART SM00387 483 591 4.1E-18 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS06870 9d61b5512da9418bea019e5b9c786655 194 SUPERFAMILY SSF46894 125 191 1.43E-16 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS06870 9d61b5512da9418bea019e5b9c786655 194 Pfam PF00196 Bacterial regulatory proteins, luxR family 131 184 1.7E-15 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS06870 9d61b5512da9418bea019e5b9c786655 194 SMART SM00421 129 186 3.7E-16 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS06870 9d61b5512da9418bea019e5b9c786655 194 Pfam PF00072 Response regulator receiver domain 11 94 8.6E-12 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS06870 9d61b5512da9418bea019e5b9c786655 194 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 162 4.8E-8 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS06870 9d61b5512da9418bea019e5b9c786655 194 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 132 146 4.8E-8 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS06870 9d61b5512da9418bea019e5b9c786655 194 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 174 4.8E-8 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS06870 9d61b5512da9418bea019e5b9c786655 194 Gene3D G3DSA:3.40.50.2300 9 132 1.2E-18 T 26-04-2017 A4V04_RS06870 9d61b5512da9418bea019e5b9c786655 194 SUPERFAMILY SSF52172 7 145 3.7E-18 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS06870 9d61b5512da9418bea019e5b9c786655 194 Gene3D G3DSA:1.10.10.10 133 191 3.5E-20 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS12450 fe8249be3fe878931cc1133012735183 68 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 66 2.2E-18 T 26-04-2017 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 A4V04_RS12450 fe8249be3fe878931cc1133012735183 68 Gene3D G3DSA:3.30.429.20 1 63 2.5E-20 T 26-04-2017 A4V04_RS12450 fe8249be3fe878931cc1133012735183 68 Pfam PF01361 Tautomerase enzyme 2 62 2.0E-15 T 26-04-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 A4V04_RS12450 fe8249be3fe878931cc1133012735183 68 SUPERFAMILY SSF55331 2 66 4.65E-13 T 26-04-2017 IPR014347 Tautomerase/MIF superfamily A4V04_RS12270 827c1f02afcf9e8795c8aee6024daead 153 Gene3D G3DSA:1.10.940.10 19 151 1.5E-36 T 26-04-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4V04_RS12270 827c1f02afcf9e8795c8aee6024daead 153 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 18 148 20.286 T 26-04-2017 IPR011605 NusB antitermination factor GO:0006353 A4V04_RS12270 827c1f02afcf9e8795c8aee6024daead 153 SUPERFAMILY SSF48013 18 149 1.15E-37 T 26-04-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4V04_RS12270 827c1f02afcf9e8795c8aee6024daead 153 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 20 146 2.2E-36 T 26-04-2017 IPR011605 NusB antitermination factor GO:0006353 A4V04_RS12270 827c1f02afcf9e8795c8aee6024daead 153 Pfam PF01029 NusB family 21 144 4.8E-29 T 26-04-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4V04_RS06515 61aec83f034a289218222fd9f6a4ab21 406 Gene3D G3DSA:2.30.30.150 347 406 2.8E-9 T 26-04-2017 IPR010575 KorB, C-terminal GO:0003677|GO:0045892 A4V04_RS06515 61aec83f034a289218222fd9f6a4ab21 406 SUPERFAMILY SSF109709 114 218 1.96E-15 T 26-04-2017 A4V04_RS06515 61aec83f034a289218222fd9f6a4ab21 406 Pfam PF06613 KorB C-terminal beta-barrel domain 352 406 3.9E-6 T 26-04-2017 IPR010575 KorB, C-terminal GO:0003677|GO:0045892 A4V04_RS06515 61aec83f034a289218222fd9f6a4ab21 406 Pfam PF08535 KorB domain 144 209 6.1E-10 T 26-04-2017 IPR013741 Transcriptional repressor protein KorB A4V04_RS06515 61aec83f034a289218222fd9f6a4ab21 406 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 30 200 3.2E-34 T 26-04-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 A4V04_RS06515 61aec83f034a289218222fd9f6a4ab21 406 SMART SM00470 29 120 2.7E-22 T 26-04-2017 IPR003115 ParB/Sulfiredoxin A4V04_RS06515 61aec83f034a289218222fd9f6a4ab21 406 Pfam PF02195 ParB-like nuclease domain 31 120 2.5E-19 T 26-04-2017 IPR003115 ParB/Sulfiredoxin A4V04_RS06515 61aec83f034a289218222fd9f6a4ab21 406 SUPERFAMILY SSF110849 17 123 3.14E-23 T 26-04-2017 IPR003115 ParB/Sulfiredoxin A4V04_RS06515 61aec83f034a289218222fd9f6a4ab21 406 Gene3D G3DSA:3.90.1530.10 24 125 1.6E-28 T 26-04-2017 A4V04_RS05120 05882778ca7be38bf2d6aaa057ea3a4d 538 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 3 537 5.4E-239 T 26-04-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A4V04_RS05120 05882778ca7be38bf2d6aaa057ea3a4d 538 Pfam PF01293 Phosphoenolpyruvate carboxykinase 18 488 2.4E-202 T 26-04-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A4V04_RS05120 05882778ca7be38bf2d6aaa057ea3a4d 538 SUPERFAMILY SSF53795 225 524 1.01E-117 T 26-04-2017 A4V04_RS05120 05882778ca7be38bf2d6aaa057ea3a4d 538 Hamap MF_00453 Phosphoenolpyruvate carboxykinase [ATP] [pckA]. 12 536 51.727 T 26-04-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A4V04_RS05120 05882778ca7be38bf2d6aaa057ea3a4d 538 Gene3D G3DSA:3.90.228.20 224 287 1.5E-110 T 26-04-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A4V04_RS05120 05882778ca7be38bf2d6aaa057ea3a4d 538 Gene3D G3DSA:3.90.228.20 348 536 1.5E-110 T 26-04-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A4V04_RS05120 05882778ca7be38bf2d6aaa057ea3a4d 538 SUPERFAMILY SSF68923 4 223 4.53E-82 T 26-04-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A4V04_RS05120 05882778ca7be38bf2d6aaa057ea3a4d 538 PIRSF PIRSF006294 1 538 4.6E-218 T 26-04-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A4V04_RS05120 05882778ca7be38bf2d6aaa057ea3a4d 538 Gene3D G3DSA:3.40.449.10 18 222 5.7E-82 T 26-04-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A4V04_RS05120 05882778ca7be38bf2d6aaa057ea3a4d 538 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 262 277 - T 26-04-2017 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A4V04_RS01815 a21fb0b403f89cc85e058f03e335724d 284 Gene3D G3DSA:3.10.450.70 69 125 1.7E-9 T 26-04-2017 IPR009094 Disulphide bond isomerase, DsbC, N-terminal A4V04_RS01815 a21fb0b403f89cc85e058f03e335724d 284 SUPERFAMILY SSF54423 74 123 3.14E-8 T 26-04-2017 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal A4V04_RS01815 a21fb0b403f89cc85e058f03e335724d 284 Pfam PF13098 Thioredoxin-like domain 149 274 9.1E-24 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS01815 a21fb0b403f89cc85e058f03e335724d 284 SUPERFAMILY SSF52833 132 277 6.28E-29 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS01815 a21fb0b403f89cc85e058f03e335724d 284 Gene3D G3DSA:3.40.30.10 147 281 1.3E-34 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS01815 a21fb0b403f89cc85e058f03e335724d 284 Pfam PF10411 Disulfide bond isomerase protein N-terminus 70 120 6.6E-14 T 26-04-2017 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal A4V04_RS12025 574cdea7e4bac9a370b41cbdc8d38ec2 476 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 6 466 1.7E-113 T 26-04-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS12025 574cdea7e4bac9a370b41cbdc8d38ec2 476 Gene3D G3DSA:3.40.1190.10 98 328 2.2E-59 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS12025 574cdea7e4bac9a370b41cbdc8d38ec2 476 SUPERFAMILY SSF53623 118 326 3.92E-43 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS12025 574cdea7e4bac9a370b41cbdc8d38ec2 476 Gene3D G3DSA:3.90.190.20 330 464 2.2E-47 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS12025 574cdea7e4bac9a370b41cbdc8d38ec2 476 Pfam PF02875 Mur ligase family, glutamate ligase domain 330 399 8.7E-8 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS12025 574cdea7e4bac9a370b41cbdc8d38ec2 476 Pfam PF08245 Mur ligase middle domain 123 308 1.1E-29 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS12025 574cdea7e4bac9a370b41cbdc8d38ec2 476 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 121 144 - T 26-04-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 A4V04_RS12025 574cdea7e4bac9a370b41cbdc8d38ec2 476 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 4 468 32.082 T 26-04-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS12025 574cdea7e4bac9a370b41cbdc8d38ec2 476 Gene3D G3DSA:3.40.50.720 2 96 9.9E-16 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS12025 574cdea7e4bac9a370b41cbdc8d38ec2 476 SUPERFAMILY SSF53244 328 468 5.95E-41 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS12025 574cdea7e4bac9a370b41cbdc8d38ec2 476 SUPERFAMILY SSF51984 2 92 4.84E-13 T 26-04-2017 A4V04_RS04005 4a28fa3545d14fbe652d30a278895081 788 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 702 729 - T 26-04-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A4V04_RS04005 4a28fa3545d14fbe652d30a278895081 788 Gene3D G3DSA:3.40.228.10 177 381 1.1E-60 T 26-04-2017 A4V04_RS04005 4a28fa3545d14fbe652d30a278895081 788 Gene3D G3DSA:3.40.50.740 382 625 2.9E-67 T 26-04-2017 A4V04_RS04005 4a28fa3545d14fbe652d30a278895081 788 Gene3D G3DSA:3.40.50.740 98 176 2.9E-67 T 26-04-2017 A4V04_RS04005 4a28fa3545d14fbe652d30a278895081 788 SUPERFAMILY SSF53706 38 667 1.44E-158 T 26-04-2017 A4V04_RS04005 4a28fa3545d14fbe652d30a278895081 788 Pfam PF01568 Molydopterin dinucleotide binding domain 671 780 6.5E-24 T 26-04-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4V04_RS04005 4a28fa3545d14fbe652d30a278895081 788 Gene3D G3DSA:2.20.25.90 37 97 6.2E-11 T 26-04-2017 A4V04_RS04005 4a28fa3545d14fbe652d30a278895081 788 Gene3D G3DSA:2.40.40.20 643 788 4.7E-49 T 26-04-2017 A4V04_RS04005 4a28fa3545d14fbe652d30a278895081 788 SUPERFAMILY SSF50692 658 788 7.23E-39 T 26-04-2017 IPR009010 Aspartate decarboxylase-like domain A4V04_RS04005 4a28fa3545d14fbe652d30a278895081 788 TIGRFAM TIGR02166 dmsA_ynfE: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family 2 788 0.0 T 26-04-2017 IPR011888 Anaerobic dimethyl sulphoxide reductase, subunit A, DmsA/YnfE GO:0009389|GO:0030151|GO:0051539|GO:0055114 A4V04_RS04005 4a28fa3545d14fbe652d30a278895081 788 Pfam PF00384 Molybdopterin oxidoreductase 96 546 9.2E-83 T 26-04-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS04005 4a28fa3545d14fbe652d30a278895081 788 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 36 93 2.1E-7 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS02105 68b543d28a28ba5f294ec209ac69fbc9 234 SUPERFAMILY SSF52096 29 143 2.09E-7 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS05790 3d2cc49a36b375d7893fd8ca705b191d 120 Pfam PF03658 RnfH family Ubiquitin 37 97 1.2E-7 T 26-04-2017 IPR005346 RnfH protein A4V04_RS05790 3d2cc49a36b375d7893fd8ca705b191d 120 Gene3D G3DSA:3.10.20.280 38 100 3.3E-10 T 26-04-2017 IPR005346 RnfH protein A4V04_RS01880 35e51eeb76326bd735923583132a263f 382 Pfam PF11348 Protein of unknown function (DUF3150) 31 208 4.3E-17 T 26-04-2017 IPR021496 Protein of unknown function DUF3150 A4V04_RS00220 e09d4304ef923330de71478bbc098141 249 Gene3D G3DSA:3.40.1210.10 1 246 6.1E-84 T 26-04-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 A4V04_RS00220 e09d4304ef923330de71478bbc098141 249 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 233 2.8E-64 T 26-04-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 A4V04_RS00220 e09d4304ef923330de71478bbc098141 249 Pfam PF01975 Survival protein SurE 3 182 1.2E-54 T 26-04-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 A4V04_RS00220 e09d4304ef923330de71478bbc098141 249 SUPERFAMILY SSF64167 1 247 3.79E-83 T 26-04-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 A4V04_RS00220 e09d4304ef923330de71478bbc098141 249 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 248 38.411 T 26-04-2017 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 A4V04_RS03065 e398ffc22a18496d7b448d829f20d5e3 449 SUPERFAMILY SSF56954 12 433 4.05E-59 T 26-04-2017 A4V04_RS03065 e398ffc22a18496d7b448d829f20d5e3 449 Gene3D G3DSA:1.20.1600.10 34 431 6.1E-50 T 26-04-2017 A4V04_RS03065 e398ffc22a18496d7b448d829f20d5e3 449 Pfam PF02321 Outer membrane efflux protein 39 227 6.3E-22 T 26-04-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A4V04_RS03065 e398ffc22a18496d7b448d829f20d5e3 449 Pfam PF02321 Outer membrane efflux protein 252 427 4.4E-25 T 26-04-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A4V04_RS07390 f59bc87a078dc79c8af5d452924c8fe0 90 ProSitePatterns PS00057 Ribosomal protein S18 signature. 37 60 - T 26-04-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07390 f59bc87a078dc79c8af5d452924c8fe0 90 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 18 89 19.726 T 26-04-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07390 f59bc87a078dc79c8af5d452924c8fe0 90 Pfam PF01084 Ribosomal protein S18 34 84 4.0E-24 T 26-04-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07390 f59bc87a078dc79c8af5d452924c8fe0 90 Gene3D G3DSA:4.10.640.10 24 89 1.6E-29 T 26-04-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07390 f59bc87a078dc79c8af5d452924c8fe0 90 TIGRFAM TIGR00165 S18: ribosomal protein bS18 21 88 1.3E-31 T 26-04-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07390 f59bc87a078dc79c8af5d452924c8fe0 90 SUPERFAMILY SSF46911 16 89 4.62E-26 T 26-04-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07390 f59bc87a078dc79c8af5d452924c8fe0 90 PRINTS PR00974 Ribosomal protein S18 family signature 44 54 9.5E-15 T 26-04-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07390 f59bc87a078dc79c8af5d452924c8fe0 90 PRINTS PR00974 Ribosomal protein S18 family signature 76 86 9.5E-15 T 26-04-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07390 f59bc87a078dc79c8af5d452924c8fe0 90 PRINTS PR00974 Ribosomal protein S18 family signature 62 76 9.5E-15 T 26-04-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07390 f59bc87a078dc79c8af5d452924c8fe0 90 PRINTS PR00974 Ribosomal protein S18 family signature 54 61 9.5E-15 T 26-04-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07390 f59bc87a078dc79c8af5d452924c8fe0 90 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 37 86 3.0E-19 T 26-04-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS04365 ea1087ac3038c7cb23a1aa0bf320e189 273 Gene3D G3DSA:3.40.109.10 84 266 2.0E-33 T 26-04-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4V04_RS04365 ea1087ac3038c7cb23a1aa0bf320e189 273 SUPERFAMILY SSF54862 7 64 2.19E-15 T 26-04-2017 A4V04_RS04365 ea1087ac3038c7cb23a1aa0bf320e189 273 SUPERFAMILY SSF55469 172 267 5.89E-33 T 26-04-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4V04_RS04365 ea1087ac3038c7cb23a1aa0bf320e189 273 SUPERFAMILY SSF55469 84 142 5.89E-33 T 26-04-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4V04_RS04365 ea1087ac3038c7cb23a1aa0bf320e189 273 Pfam PF00881 Nitroreductase family 86 253 2.0E-26 T 26-04-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4V04_RS04365 ea1087ac3038c7cb23a1aa0bf320e189 273 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS04365 ea1087ac3038c7cb23a1aa0bf320e189 273 Pfam PF13187 4Fe-4S dicluster domain 11 57 4.3E-10 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS04365 ea1087ac3038c7cb23a1aa0bf320e189 273 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 11 22 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS04365 ea1087ac3038c7cb23a1aa0bf320e189 273 Gene3D G3DSA:3.30.70.20 7 66 2.4E-14 T 26-04-2017 A4V04_RS07925 c1d352b27d6aa8fb83032efcdd88d54a 141 Pfam PF00581 Rhodanese-like domain 48 133 4.4E-7 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS07925 c1d352b27d6aa8fb83032efcdd88d54a 141 SMART SM00450 42 137 5.9E-6 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS07925 c1d352b27d6aa8fb83032efcdd88d54a 141 Gene3D G3DSA:3.40.250.10 35 140 9.0E-17 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS07925 c1d352b27d6aa8fb83032efcdd88d54a 141 SUPERFAMILY SSF52821 40 140 1.17E-16 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS06415 27444398876f3f1ca590c1742702fc88 238 Pfam PF07424 TrbM 47 87 8.6E-5 T 26-04-2017 IPR009989 TrbM A4V04_RS08055 d8af37cde2206e49a841437c19102904 366 Gene3D G3DSA:3.20.20.70 21 359 1.0E-135 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS08055 d8af37cde2206e49a841437c19102904 366 PIRSF PIRSF001361 6 365 4.6E-150 T 26-04-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4V04_RS08055 d8af37cde2206e49a841437c19102904 366 SUPERFAMILY SSF51569 19 357 3.77E-124 T 26-04-2017 A4V04_RS08055 d8af37cde2206e49a841437c19102904 366 Pfam PF00793 DAHP synthetase I family 56 351 2.5E-91 T 26-04-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A4V04_RS08055 d8af37cde2206e49a841437c19102904 366 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 18 359 5.5E-141 T 26-04-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4V04_RS06105 a0276067f1c474019fda51d9d7da11bd 199 Pfam PF12804 MobA-like NTP transferase domain 10 162 1.3E-28 T 26-04-2017 IPR025877 MobA-like NTP transferase A4V04_RS06105 a0276067f1c474019fda51d9d7da11bd 199 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 6 194 25.328 T 26-04-2017 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 A4V04_RS06105 a0276067f1c474019fda51d9d7da11bd 199 SUPERFAMILY SSF53448 5 194 4.22E-29 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS06105 a0276067f1c474019fda51d9d7da11bd 199 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 9 191 7.4E-49 T 26-04-2017 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 A4V04_RS06105 a0276067f1c474019fda51d9d7da11bd 199 Gene3D G3DSA:3.90.550.10 4 196 1.6E-44 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS03715 0d4c13ded0c6f9f122b7e18f3e87bd85 417 Gene3D G3DSA:3.40.50.920 252 380 2.7E-29 T 26-04-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4V04_RS03715 0d4c13ded0c6f9f122b7e18f3e87bd85 417 SUPERFAMILY SSF52922 252 373 1.96E-26 T 26-04-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4V04_RS03715 0d4c13ded0c6f9f122b7e18f3e87bd85 417 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 232 8.9E-65 T 26-04-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A4V04_RS03715 0d4c13ded0c6f9f122b7e18f3e87bd85 417 Gene3D G3DSA:3.40.50.970 3 246 2.0E-76 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS03715 0d4c13ded0c6f9f122b7e18f3e87bd85 417 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 259 357 5.2E-26 T 26-04-2017 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A4V04_RS03715 0d4c13ded0c6f9f122b7e18f3e87bd85 417 SUPERFAMILY SSF52518 4 246 2.62E-62 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS03300 d502aad712eee7f4bb2d7e63ec59b6c4 236 Gene3D G3DSA:1.10.3130.10 1 61 5.7E-26 T 26-04-2017 A4V04_RS03300 d502aad712eee7f4bb2d7e63ec59b6c4 236 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 5 167 3.3E-73 T 26-04-2017 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A4V04_RS03300 d502aad712eee7f4bb2d7e63ec59b6c4 236 SUPERFAMILY SSF51161 4 173 1.04E-55 T 26-04-2017 IPR011004 Trimeric LpxA-like A4V04_RS03300 d502aad712eee7f4bb2d7e63ec59b6c4 236 Pfam PF06426 Serine acetyltransferase, N-terminal 2 35 8.7E-5 T 26-04-2017 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A4V04_RS03300 d502aad712eee7f4bb2d7e63ec59b6c4 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 152 6.4E-9 T 26-04-2017 IPR001451 Hexapeptide repeat A4V04_RS03300 d502aad712eee7f4bb2d7e63ec59b6c4 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 72 108 1.5E-6 T 26-04-2017 IPR001451 Hexapeptide repeat A4V04_RS03300 d502aad712eee7f4bb2d7e63ec59b6c4 236 Gene3D G3DSA:2.160.10.10 62 216 3.1E-38 T 26-04-2017 A4V04_RS08660 92713f8e2e3c8004727123bd7c2c9ee5 300 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 157 172 2.9E-65 T 26-04-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08660 92713f8e2e3c8004727123bd7c2c9ee5 300 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 250 266 2.9E-65 T 26-04-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08660 92713f8e2e3c8004727123bd7c2c9ee5 300 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 77 97 2.9E-65 T 26-04-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08660 92713f8e2e3c8004727123bd7c2c9ee5 300 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 108 132 2.9E-65 T 26-04-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08660 92713f8e2e3c8004727123bd7c2c9ee5 300 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 56 71 2.9E-65 T 26-04-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08660 92713f8e2e3c8004727123bd7c2c9ee5 300 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 134 154 2.9E-65 T 26-04-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08660 92713f8e2e3c8004727123bd7c2c9ee5 300 Gene3D G3DSA:3.30.930.10 1 212 3.6E-100 T 26-04-2017 A4V04_RS08660 92713f8e2e3c8004727123bd7c2c9ee5 300 SUPERFAMILY SSF55681 3 289 6.63E-125 T 26-04-2017 A4V04_RS08660 92713f8e2e3c8004727123bd7c2c9ee5 300 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 2 290 57.884 T 26-04-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08660 92713f8e2e3c8004727123bd7c2c9ee5 300 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 4 289 1.3E-143 T 26-04-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08660 92713f8e2e3c8004727123bd7c2c9ee5 300 Gene3D G3DSA:1.20.58.180 214 295 4.4E-36 T 26-04-2017 A4V04_RS08660 92713f8e2e3c8004727123bd7c2c9ee5 300 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 3 298 4.6E-150 T 26-04-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS11595 b464d5685d2014fcbef5c4983b3e9082 325 SUPERFAMILY SSF161098 108 306 3.53E-11 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS11595 b464d5685d2014fcbef5c4983b3e9082 325 Gene3D G3DSA:1.10.3720.10 105 312 8.0E-12 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS11595 b464d5685d2014fcbef5c4983b3e9082 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 131 323 4.7E-26 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS02420 26620b5813e00b8d8bd7c3e9c286dd1b 134 Gene3D G3DSA:3.90.700.10 8 52 4.2E-13 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02420 26620b5813e00b8d8bd7c3e9c286dd1b 134 Pfam PF00890 FAD binding domain 19 108 3.6E-13 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02420 26620b5813e00b8d8bd7c3e9c286dd1b 134 Gene3D G3DSA:3.50.50.60 53 133 2.0E-14 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02420 26620b5813e00b8d8bd7c3e9c286dd1b 134 SUPERFAMILY SSF56425 7 74 1.67E-12 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02420 26620b5813e00b8d8bd7c3e9c286dd1b 134 SUPERFAMILY SSF51905 73 133 1.02E-7 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12845 29d3f5cd0db618e12d4467e1ec47fb5b 384 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 43 378 3.6E-67 T 26-04-2017 IPR010327 FldB/FldC dehydratase alpha/beta subunit A4V04_RS08365 611152f65ee85f7793a25a13553dce81 403 SUPERFAMILY SSF53187 16 211 2.05E-69 T 26-04-2017 A4V04_RS08365 611152f65ee85f7793a25a13553dce81 403 SUPERFAMILY SSF53187 314 398 2.05E-69 T 26-04-2017 A4V04_RS08365 611152f65ee85f7793a25a13553dce81 403 Gene3D G3DSA:3.40.630.10 12 192 4.8E-76 T 26-04-2017 A4V04_RS08365 611152f65ee85f7793a25a13553dce81 403 Gene3D G3DSA:3.40.630.10 314 400 4.8E-76 T 26-04-2017 A4V04_RS08365 611152f65ee85f7793a25a13553dce81 403 Pfam PF01546 Peptidase family M20/M25/M40 87 395 5.0E-23 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS08365 611152f65ee85f7793a25a13553dce81 403 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 27 386 6.1E-93 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS08365 611152f65ee85f7793a25a13553dce81 403 PIRSF PIRSF005962 10 401 1.5E-107 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS08365 611152f65ee85f7793a25a13553dce81 403 Gene3D G3DSA:3.30.70.360 195 313 3.2E-43 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS08365 611152f65ee85f7793a25a13553dce81 403 Pfam PF07687 Peptidase dimerisation domain 200 297 9.4E-10 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS08365 611152f65ee85f7793a25a13553dce81 403 SUPERFAMILY SSF55031 198 312 4.06E-30 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS00290 795001a724b11b4c8bff035bc084729b 78 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 64 27.358 T 26-04-2017 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A4V04_RS00290 795001a724b11b4c8bff035bc084729b 78 Gene3D G3DSA:2.30.30.100 1 70 5.4E-36 T 26-04-2017 A4V04_RS00290 795001a724b11b4c8bff035bc084729b 78 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 7 64 8.5E-29 T 26-04-2017 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A4V04_RS00290 795001a724b11b4c8bff035bc084729b 78 SUPERFAMILY SSF50182 7 69 5.01E-24 T 26-04-2017 IPR010920 LSM domain A4V04_RS11255 f80d9e293fe64ec7521edcf149873576 267 Gene3D G3DSA:3.30.300.20 17 107 1.2E-31 T 26-04-2017 IPR015946 K homology domain-like, alpha/beta A4V04_RS11255 f80d9e293fe64ec7521edcf149873576 267 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.282 T 26-04-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A4V04_RS11255 f80d9e293fe64ec7521edcf149873576 267 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 3.0E-41 T 26-04-2017 A4V04_RS11255 f80d9e293fe64ec7521edcf149873576 267 SMART SM00322 60 125 3.5E-7 T 26-04-2017 IPR004087 K Homology domain GO:0003676 A4V04_RS11255 f80d9e293fe64ec7521edcf149873576 267 SUPERFAMILY SSF54814 2 106 8.63E-37 T 26-04-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 A4V04_RS11255 f80d9e293fe64ec7521edcf149873576 267 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 3.5E-92 T 26-04-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A4V04_RS11255 f80d9e293fe64ec7521edcf149873576 267 SUPERFAMILY SSF54821 108 206 1.7E-39 T 26-04-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11255 f80d9e293fe64ec7521edcf149873576 267 Pfam PF07650 KH domain 38 110 1.8E-19 T 26-04-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11255 f80d9e293fe64ec7521edcf149873576 267 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 26-04-2017 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11255 f80d9e293fe64ec7521edcf149873576 267 Gene3D G3DSA:3.30.1140.32 109 206 7.2E-46 T 26-04-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS09875 c167bfb83d312a97d6ca3ec2b187b4a7 697 SUPERFAMILY SSF48310 254 696 2.49E-43 T 26-04-2017 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A4V04_RS09875 c167bfb83d312a97d6ca3ec2b187b4a7 697 SUPERFAMILY SSF56228 7 211 1.96E-55 T 26-04-2017 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A4V04_RS09875 c167bfb83d312a97d6ca3ec2b187b4a7 697 SMART SM00790 9 208 7.7E-72 T 26-04-2017 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A4V04_RS09875 c167bfb83d312a97d6ca3ec2b187b4a7 697 Gene3D G3DSA:1.10.569.10 301 437 3.1E-5 T 26-04-2017 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A4V04_RS09875 c167bfb83d312a97d6ca3ec2b187b4a7 697 Gene3D G3DSA:1.10.599.10 438 686 1.4E-45 T 26-04-2017 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A4V04_RS09875 c167bfb83d312a97d6ca3ec2b187b4a7 697 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 300 683 1.0E-46 T 26-04-2017 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A4V04_RS09875 c167bfb83d312a97d6ca3ec2b187b4a7 697 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 12 206 1.6E-61 T 26-04-2017 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A4V04_RS09875 c167bfb83d312a97d6ca3ec2b187b4a7 697 Gene3D G3DSA:3.60.9.10 7 211 1.4E-69 T 26-04-2017 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A4V04_RS09975 d7e4c6344f47a39196ba9d2c8e47323f 433 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 311 322 - T 26-04-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS09975 d7e4c6344f47a39196ba9d2c8e47323f 433 SUPERFAMILY SSF53335 135 433 8.86E-63 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS09975 d7e4c6344f47a39196ba9d2c8e47323f 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 246 256 5.7E-22 T 26-04-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS09975 d7e4c6344f47a39196ba9d2c8e47323f 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 362 378 5.7E-22 T 26-04-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS09975 d7e4c6344f47a39196ba9d2c8e47323f 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 415 432 5.7E-22 T 26-04-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS09975 d7e4c6344f47a39196ba9d2c8e47323f 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 217 231 5.7E-22 T 26-04-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS09975 d7e4c6344f47a39196ba9d2c8e47323f 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 312 324 5.7E-22 T 26-04-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS09975 d7e4c6344f47a39196ba9d2c8e47323f 433 Gene3D G3DSA:3.40.50.150 227 432 1.4E-45 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS09975 d7e4c6344f47a39196ba9d2c8e47323f 433 Pfam PF01189 16S rRNA methyltransferase RsmB/F 234 430 2.4E-49 T 26-04-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS09975 d7e4c6344f47a39196ba9d2c8e47323f 433 Gene3D G3DSA:3.30.70.1170 169 225 1.0E-15 T 26-04-2017 A4V04_RS09975 d7e4c6344f47a39196ba9d2c8e47323f 433 Pfam PF01029 NusB family 29 122 6.3E-8 T 26-04-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4V04_RS09975 d7e4c6344f47a39196ba9d2c8e47323f 433 Gene3D G3DSA:1.10.940.10 27 146 1.0E-17 T 26-04-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4V04_RS09975 d7e4c6344f47a39196ba9d2c8e47323f 433 SUPERFAMILY SSF48013 25 145 3.27E-16 T 26-04-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4V04_RS09975 d7e4c6344f47a39196ba9d2c8e47323f 433 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 36 432 6.4E-84 T 26-04-2017 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 SUPERFAMILY SSF82693 565 677 4.71E-19 T 26-04-2017 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 Gene3D G3DSA:3.30.70.1320 138 199 1.9E-12 T 26-04-2017 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 PRINTS PR00702 Acriflavin resistance protein family signature 448 471 2.1E-87 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 2.1E-87 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 2.1E-87 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 2.1E-87 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 PRINTS PR00702 Acriflavin resistance protein family signature 473 496 2.1E-87 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 PRINTS PR00702 Acriflavin resistance protein family signature 621 635 2.1E-87 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 2.1E-87 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 2.1E-87 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 2.1E-87 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 2 1036 0.0 T 26-04-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 Gene3D G3DSA:3.30.2090.10 729 813 1.9E-22 T 26-04-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 Gene3D G3DSA:3.30.2090.10 200 274 1.6E-17 T 26-04-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 Gene3D G3DSA:3.30.70.1430 567 677 9.0E-22 T 26-04-2017 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 Gene3D G3DSA:3.30.70.1430 40 137 4.6E-32 T 26-04-2017 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 SUPERFAMILY SSF82866 811 1038 1.03E-43 T 26-04-2017 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 Gene3D G3DSA:1.10.3850.10 284 501 7.6E-54 T 26-04-2017 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 Gene3D G3DSA:1.10.3850.10 821 1033 4.3E-57 T 26-04-2017 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 Pfam PF00873 AcrB/AcrD/AcrF family 2 1032 0.0 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 SUPERFAMILY SSF82714 729 813 1.83E-20 T 26-04-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 SUPERFAMILY SSF82693 277 333 6.8E-22 T 26-04-2017 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 SUPERFAMILY SSF82693 137 183 6.8E-22 T 26-04-2017 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 SUPERFAMILY SSF82714 185 274 1.09E-15 T 26-04-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 SUPERFAMILY SSF82693 40 133 3.14E-26 T 26-04-2017 A4V04_RS03525 461b04e8a28b1f7e4b8fe4918bb38c4c 1160 SUPERFAMILY SSF82866 299 499 4.32E-47 T 26-04-2017 A4V04_RS05705 f39e490beb03fb31c17d8df4ff30f514 599 Pfam PF01609 Transposase DDE domain 245 509 2.7E-13 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS05705 f39e490beb03fb31c17d8df4ff30f514 599 SUPERFAMILY SSF53098 184 396 9.86E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS05705 f39e490beb03fb31c17d8df4ff30f514 599 SUPERFAMILY SSF53098 448 522 9.86E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS10965 f39e490beb03fb31c17d8df4ff30f514 599 Pfam PF01609 Transposase DDE domain 245 509 2.7E-13 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS10965 f39e490beb03fb31c17d8df4ff30f514 599 SUPERFAMILY SSF53098 184 396 9.86E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS10965 f39e490beb03fb31c17d8df4ff30f514 599 SUPERFAMILY SSF53098 448 522 9.86E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS05980 753194f63639ce24fb1493bb9ac20a9f 142 PIRSF PIRSF032131 3 141 7.9E-39 T 26-04-2017 IPR009562 Protein of unknown function DUF1178 A4V04_RS05980 753194f63639ce24fb1493bb9ac20a9f 142 Pfam PF06676 Protein of unknown function (DUF1178) 3 136 9.9E-38 T 26-04-2017 IPR009562 Protein of unknown function DUF1178 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 SMART SM00278 459 478 0.12 T 26-04-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 SMART SM00278 493 512 7.1 T 26-04-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 SMART SM00278 557 576 1.2 T 26-04-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 SMART SM00278 525 544 120.0 T 26-04-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 SUPERFAMILY SSF50249 331 413 1.1E-27 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 22 676 2.5E-241 T 26-04-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 Gene3D G3DSA:1.10.150.20 517 597 3.2E-28 T 26-04-2017 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 421 447 2.2E-10 T 26-04-2017 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 Gene3D G3DSA:1.10.150.20 448 516 1.5E-29 T 26-04-2017 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 SUPERFAMILY SSF56091 14 329 9.05E-108 T 26-04-2017 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 344 359 - T 26-04-2017 IPR033136 NAD-dependent DNA ligase, conserved site A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 Pfam PF12826 Helix-hairpin-helix motif 523 586 4.4E-19 T 26-04-2017 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 SMART SM00292 606 683 1.1E-13 T 26-04-2017 IPR001357 BRCT domain A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 334 411 1.2E-33 T 26-04-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 PIRSF PIRSF001604 6 685 1.7E-238 T 26-04-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 SMART SM00532 14 461 2.4E-231 T 26-04-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 14 331 1.5E-108 T 26-04-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 Gene3D G3DSA:2.40.50.140 333 404 6.0E-32 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 606 677 1.1E-14 T 26-04-2017 IPR001357 BRCT domain A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 Gene3D G3DSA:3.30.470.30 135 265 5.4E-50 T 26-04-2017 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 Hamap MF_01588 DNA ligase [ligA]. 13 680 50.688 T 26-04-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 131 160 - T 26-04-2017 IPR018239 NAD-dependent DNA ligase, active site A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 SUPERFAMILY SSF52113 606 683 1.37E-19 T 26-04-2017 IPR001357 BRCT domain A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 Pfam PF14520 Helix-hairpin-helix domain 459 513 3.1E-8 T 26-04-2017 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 SUPERFAMILY SSF47781 416 597 4.82E-61 T 26-04-2017 IPR010994 RuvA domain 2-like A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 Gene3D G3DSA:1.10.287.610 10 77 1.6E-24 T 26-04-2017 A4V04_RS05940 078661c95cb3888e2136460bef0ca2e3 686 Gene3D G3DSA:3.40.50.10190 606 683 1.3E-24 T 26-04-2017 IPR001357 BRCT domain A4V04_RS07945 fd6296855f22eb867717f5e2e942ef13 240 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 33.655 T 26-04-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4V04_RS07945 fd6296855f22eb867717f5e2e942ef13 240 Pfam PF01709 Transcriptional regulator 5 236 6.5E-90 T 26-04-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4V04_RS07945 fd6296855f22eb867717f5e2e942ef13 240 Gene3D G3DSA:1.10.10.200 1 78 3.9E-33 T 26-04-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like A4V04_RS07945 fd6296855f22eb867717f5e2e942ef13 240 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 4.8E-89 T 26-04-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4V04_RS07945 fd6296855f22eb867717f5e2e942ef13 240 SUPERFAMILY SSF75625 3 237 3.66E-90 T 26-04-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4V04_RS07945 fd6296855f22eb867717f5e2e942ef13 240 Gene3D G3DSA:3.30.1270.10 82 134 1.4E-36 T 26-04-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4V04_RS07945 fd6296855f22eb867717f5e2e942ef13 240 Gene3D G3DSA:3.30.1270.10 212 238 1.4E-36 T 26-04-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4V04_RS07945 fd6296855f22eb867717f5e2e942ef13 240 Gene3D G3DSA:3.30.70.980 135 203 8.1E-26 T 26-04-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 Gene3D G3DSA:1.10.10.10 663 714 1.3E-23 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 Pfam PF04545 Sigma-70, region 4 758 811 1.9E-19 T 26-04-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 586 822 9.8E-118 T 26-04-2017 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 Pfam PF04539 Sigma-70 region 3 669 745 2.6E-24 T 26-04-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 SUPERFAMILY SSF88659 663 736 8.51E-18 T 26-04-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 Pfam PF04546 Sigma-70, non-essential region 362 559 1.2E-55 T 26-04-2017 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 SUPERFAMILY SSF88946 338 657 1.88E-94 T 26-04-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 SUPERFAMILY SSF88659 720 821 1.23E-25 T 26-04-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 Pfam PF00140 Sigma-70 factor, region 1.2 321 353 1.6E-13 T 26-04-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 Pfam PF04542 Sigma-70 region 2 592 659 1.1E-20 T 26-04-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 586 811 2.9E-38 T 26-04-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 Gene3D G3DSA:1.10.10.10 753 823 1.3E-32 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 Gene3D G3DSA:1.10.601.10 338 659 8.3E-115 T 26-04-2017 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 Gene3D G3DSA:1.10.601.10 153 337 3.7E-4 T 26-04-2017 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 614 627 - T 26-04-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 Pfam PF03979 Sigma-70 factor, region 1.1 226 303 2.5E-25 T 26-04-2017 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 PRINTS PR00046 Major sigma-70 factor signature 762 774 2.3E-30 T 26-04-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 PRINTS PR00046 Major sigma-70 factor signature 638 646 2.3E-30 T 26-04-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 PRINTS PR00046 Major sigma-70 factor signature 783 798 2.3E-30 T 26-04-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 PRINTS PR00046 Major sigma-70 factor signature 798 809 2.3E-30 T 26-04-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 PRINTS PR00046 Major sigma-70 factor signature 614 627 2.3E-30 T 26-04-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 223 823 40.971 T 26-04-2017 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 A4V04_RS00885 32d61b060770b6b15c834dd6e98d66b1 828 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 783 809 - T 26-04-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS12740 89fbadb5d08e8b0ad748db60bc9e38dd 489 SUPERFAMILY SSF51971 142 418 1.09E-58 T 26-04-2017 A4V04_RS12740 89fbadb5d08e8b0ad748db60bc9e38dd 489 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 145 476 3.1E-26 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12740 89fbadb5d08e8b0ad748db60bc9e38dd 489 Gene3D G3DSA:1.10.1060.10 4 145 1.4E-38 T 26-04-2017 A4V04_RS12740 89fbadb5d08e8b0ad748db60bc9e38dd 489 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 131 8.3E-24 T 26-04-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A4V04_RS12740 89fbadb5d08e8b0ad748db60bc9e38dd 489 Gene3D G3DSA:3.50.50.60 146 255 1.1E-27 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12740 89fbadb5d08e8b0ad748db60bc9e38dd 489 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 487 1.4E-187 T 26-04-2017 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 A4V04_RS12740 89fbadb5d08e8b0ad748db60bc9e38dd 489 Gene3D G3DSA:3.50.50.60 408 487 9.2E-18 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12740 89fbadb5d08e8b0ad748db60bc9e38dd 489 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 1.5E-19 T 26-04-2017 A4V04_RS12740 89fbadb5d08e8b0ad748db60bc9e38dd 489 PRINTS PR00419 Adrenodoxin reductase family signature 297 311 1.5E-19 T 26-04-2017 A4V04_RS12740 89fbadb5d08e8b0ad748db60bc9e38dd 489 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 1.5E-19 T 26-04-2017 A4V04_RS12740 89fbadb5d08e8b0ad748db60bc9e38dd 489 SUPERFAMILY SSF46548 2 153 5.18E-36 T 26-04-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 A4V04_RS12740 89fbadb5d08e8b0ad748db60bc9e38dd 489 Gene3D G3DSA:3.50.50.60 256 407 5.9E-37 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10525 9426e75ea8d0b5c85a33c209643c82c6 506 Pfam PF00890 FAD binding domain 42 483 1.2E-81 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10525 9426e75ea8d0b5c85a33c209643c82c6 506 Gene3D G3DSA:3.90.700.10 306 434 1.0E-17 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10525 9426e75ea8d0b5c85a33c209643c82c6 506 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 43 62 9.0E-5 T 26-04-2017 A4V04_RS10525 9426e75ea8d0b5c85a33c209643c82c6 506 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 448 470 9.0E-5 T 26-04-2017 A4V04_RS10525 9426e75ea8d0b5c85a33c209643c82c6 506 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 42 495 6.4E-149 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS10525 9426e75ea8d0b5c85a33c209643c82c6 506 SUPERFAMILY SSF51905 442 502 4.64E-49 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10525 9426e75ea8d0b5c85a33c209643c82c6 506 SUPERFAMILY SSF51905 39 297 4.64E-49 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10525 9426e75ea8d0b5c85a33c209643c82c6 506 Gene3D G3DSA:3.50.50.60 38 280 7.7E-77 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10525 9426e75ea8d0b5c85a33c209643c82c6 506 Gene3D G3DSA:3.50.50.60 439 500 7.7E-77 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10525 9426e75ea8d0b5c85a33c209643c82c6 506 SUPERFAMILY SSF56425 286 443 2.09E-25 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10790 95fda4ca5f2b792aa04749ff357e7185 366 Pfam PF13609 Gram-negative porin 22 341 2.9E-30 T 26-04-2017 A4V04_RS10790 95fda4ca5f2b792aa04749ff357e7185 366 Gene3D G3DSA:2.40.160.10 22 366 1.9E-52 T 26-04-2017 IPR023614 Porin domain A4V04_RS10790 95fda4ca5f2b792aa04749ff357e7185 366 SUPERFAMILY SSF56935 23 350 4.58E-43 T 26-04-2017 A4V04_RS11365 265a316ea29699d489a5eac0646c4a52 345 SUPERFAMILY SSF53474 66 325 2.01E-45 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS11365 265a316ea29699d489a5eac0646c4a52 345 Gene3D G3DSA:3.40.50.1820 66 325 8.2E-64 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS11365 265a316ea29699d489a5eac0646c4a52 345 Pfam PF07859 alpha/beta hydrolase fold 86 307 8.0E-24 T 26-04-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 A4V04_RS11625 2ed9d430d563799b761edcd3e8b8b561 508 SUPERFAMILY SSF82861 231 315 1.31E-10 T 26-04-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A4V04_RS11625 2ed9d430d563799b761edcd3e8b8b561 508 SUPERFAMILY SSF50182 317 382 8.5E-16 T 26-04-2017 IPR010920 LSM domain A4V04_RS11625 2ed9d430d563799b761edcd3e8b8b561 508 Pfam PF00924 Mechanosensitive ion channel 275 474 4.3E-49 T 26-04-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A4V04_RS11625 2ed9d430d563799b761edcd3e8b8b561 508 Gene3D G3DSA:3.30.70.100 389 472 1.0E-15 T 26-04-2017 A4V04_RS11625 2ed9d430d563799b761edcd3e8b8b561 508 SUPERFAMILY SSF82689 389 483 2.35E-22 T 26-04-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A4V04_RS11625 2ed9d430d563799b761edcd3e8b8b561 508 Gene3D G3DSA:2.30.30.60 333 381 2.1E-15 T 26-04-2017 A4V04_RS04760 6390564bdcf783213fcc7b1da84f5148 112 SUPERFAMILY SSF48695 32 103 2.6E-12 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS04760 6390564bdcf783213fcc7b1da84f5148 112 Gene3D G3DSA:1.10.760.10 4 45 6.2E-4 T 26-04-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4V04_RS04760 6390564bdcf783213fcc7b1da84f5148 112 Pfam PF14537 Cytochrome c3 29 100 6.6E-13 T 26-04-2017 A4V04_RS04760 6390564bdcf783213fcc7b1da84f5148 112 Gene3D G3DSA:3.90.10.10 46 106 1.6E-8 T 26-04-2017 A4V04_RS07355 408fed5fb92506b06711e840d7e530f6 766 SUPERFAMILY SSF53706 338 651 1.83E-144 T 26-04-2017 A4V04_RS07355 408fed5fb92506b06711e840d7e530f6 766 SUPERFAMILY SSF53706 43 283 1.83E-144 T 26-04-2017 A4V04_RS07355 408fed5fb92506b06711e840d7e530f6 766 Gene3D G3DSA:3.40.50.740 405 589 1.5E-37 T 26-04-2017 A4V04_RS07355 408fed5fb92506b06711e840d7e530f6 766 Gene3D G3DSA:3.40.228.10 338 404 8.5E-52 T 26-04-2017 A4V04_RS07355 408fed5fb92506b06711e840d7e530f6 766 Gene3D G3DSA:3.40.228.10 177 283 8.5E-52 T 26-04-2017 A4V04_RS07355 408fed5fb92506b06711e840d7e530f6 766 Pfam PF01568 Molydopterin dinucleotide binding domain 652 745 1.6E-19 T 26-04-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4V04_RS07355 408fed5fb92506b06711e840d7e530f6 766 Gene3D G3DSA:2.20.25.90 40 95 1.0E-6 T 26-04-2017 A4V04_RS07355 408fed5fb92506b06711e840d7e530f6 766 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 501 518 - T 26-04-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A4V04_RS07355 408fed5fb92506b06711e840d7e530f6 766 SUPERFAMILY SSF50692 642 766 6.56E-30 T 26-04-2017 IPR009010 Aspartate decarboxylase-like domain A4V04_RS07355 408fed5fb92506b06711e840d7e530f6 766 Pfam PF00384 Molybdopterin oxidoreductase 95 557 1.7E-66 T 26-04-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS07355 408fed5fb92506b06711e840d7e530f6 766 Gene3D G3DSA:3.40.50.740 96 176 2.4E-15 T 26-04-2017 A4V04_RS07355 408fed5fb92506b06711e840d7e530f6 766 Gene3D G3DSA:2.40.40.20 625 766 1.1E-32 T 26-04-2017 A4V04_RS12695 de2a8a1056d3163696c2d38c372496b4 204 Gene3D G3DSA:3.10.450.50 117 173 3.9E-25 T 26-04-2017 IPR032710 NTF2-like domain A4V04_RS12695 de2a8a1056d3163696c2d38c372496b4 204 Gene3D G3DSA:3.10.450.50 29 73 3.9E-25 T 26-04-2017 IPR032710 NTF2-like domain A4V04_RS12695 de2a8a1056d3163696c2d38c372496b4 204 PIRSF PIRSF004649 1 204 6.1E-49 T 26-04-2017 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC A4V04_RS12695 de2a8a1056d3163696c2d38c372496b4 204 Gene3D G3DSA:1.10.10.640 174 203 1.5E-28 T 26-04-2017 IPR023094 Toluene tolerance protein, alpha-helical A4V04_RS12695 de2a8a1056d3163696c2d38c372496b4 204 Gene3D G3DSA:1.10.10.640 74 114 1.5E-28 T 26-04-2017 IPR023094 Toluene tolerance protein, alpha-helical A4V04_RS12695 de2a8a1056d3163696c2d38c372496b4 204 Pfam PF05494 MlaC protein 36 200 2.7E-52 T 26-04-2017 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 6 442 6.8E-172 T 26-04-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 98 107 - T 26-04-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 2 445 43.101 T 26-04-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 Gene3D G3DSA:3.40.120.10 256 367 7.9E-32 T 26-04-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 2.5E-12 T 26-04-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 176 195 2.5E-12 T 26-04-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 2.5E-12 T 26-04-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 366 2.7E-33 T 26-04-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 138 9.7E-42 T 26-04-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 Gene3D G3DSA:3.30.310.50 371 442 2.0E-16 T 26-04-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 439 1.2E-16 T 26-04-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 SUPERFAMILY SSF55957 358 442 2.22E-20 T 26-04-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 Gene3D G3DSA:3.40.120.10 3 154 8.5E-46 T 26-04-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 Gene3D G3DSA:3.40.120.10 178 251 7.0E-21 T 26-04-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 SUPERFAMILY SSF53738 2 183 5.1E-47 T 26-04-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 SUPERFAMILY SSF53738 259 366 1.53E-30 T 26-04-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 159 254 2.9E-15 T 26-04-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12960 abe1e1c9ba6f337a275e30de0a3d80b7 445 SUPERFAMILY SSF53738 158 255 1.61E-25 T 26-04-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4V04_RS12075 1b05678f8762fd49560bcf822ede7684 430 Gene3D G3DSA:3.40.640.10 70 317 1.4E-78 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS12075 1b05678f8762fd49560bcf822ede7684 430 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 26-04-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4V04_RS12075 1b05678f8762fd49560bcf822ede7684 430 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 425 99.424 T 26-04-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A4V04_RS12075 1b05678f8762fd49560bcf822ede7684 430 SUPERFAMILY SSF53383 2 424 4.99E-126 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS12075 1b05678f8762fd49560bcf822ede7684 430 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 424 2.1E-183 T 26-04-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A4V04_RS12075 1b05678f8762fd49560bcf822ede7684 430 Gene3D G3DSA:3.90.1150.10 319 424 5.6E-39 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS12075 1b05678f8762fd49560bcf822ede7684 430 Gene3D G3DSA:3.90.1150.10 3 69 5.6E-39 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS12075 1b05678f8762fd49560bcf822ede7684 430 Pfam PF00202 Aminotransferase class-III 34 395 3.7E-72 T 26-04-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4V04_RS08655 abff5cd5ecceb6c0f970c742867e6506 696 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 2 694 1.1E-196 T 26-04-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08655 abff5cd5ecceb6c0f970c742867e6506 696 Pfam PF05746 DALR anticodon binding domain 587 687 1.8E-10 T 26-04-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A4V04_RS08655 abff5cd5ecceb6c0f970c742867e6506 696 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 1 694 23.818 T 26-04-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08655 abff5cd5ecceb6c0f970c742867e6506 696 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 4 556 3.2E-190 T 26-04-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08655 abff5cd5ecceb6c0f970c742867e6506 696 SUPERFAMILY SSF109604 356 496 6.73E-16 T 26-04-2017 A4V04_RS08655 abff5cd5ecceb6c0f970c742867e6506 696 Gene3D G3DSA:1.10.730.10 588 687 6.1E-7 T 26-04-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS08655 abff5cd5ecceb6c0f970c742867e6506 696 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 400 419 4.1E-30 T 26-04-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08655 abff5cd5ecceb6c0f970c742867e6506 696 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 50 62 4.1E-30 T 26-04-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08655 abff5cd5ecceb6c0f970c742867e6506 696 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 251 266 4.1E-30 T 26-04-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08655 abff5cd5ecceb6c0f970c742867e6506 696 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 5 18 4.1E-30 T 26-04-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS08655 abff5cd5ecceb6c0f970c742867e6506 696 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 324 340 4.1E-30 T 26-04-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4V04_RS00315 503b2bdb46a7de7a95fbd5a6a1d5d5a1 387 SUPERFAMILY SSF55681 4 317 2.14E-48 T 26-04-2017 A4V04_RS00315 503b2bdb46a7de7a95fbd5a6a1d5d5a1 387 Pfam PF13393 Histidyl-tRNA synthetase 10 313 2.3E-93 T 26-04-2017 A4V04_RS00315 503b2bdb46a7de7a95fbd5a6a1d5d5a1 387 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 364 27.09 T 26-04-2017 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A4V04_RS00315 503b2bdb46a7de7a95fbd5a6a1d5d5a1 387 Gene3D G3DSA:3.30.930.10 17 313 4.0E-57 T 26-04-2017 A4V04_RS00315 503b2bdb46a7de7a95fbd5a6a1d5d5a1 387 PIRSF PIRSF001549 5 372 6.3E-43 T 26-04-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A4V04_RS13230 a584f69bf7f5f13d3d50f69f0da9ccf3 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 1.3E-38 T 26-04-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 A4V04_RS13230 a584f69bf7f5f13d3d50f69f0da9ccf3 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 2.6E-24 T 26-04-2017 IPR000361 FeS cluster biogenesis A4V04_RS13230 a584f69bf7f5f13d3d50f69f0da9ccf3 107 SUPERFAMILY SSF89360 1 96 1.23E-31 T 26-04-2017 IPR000361 FeS cluster biogenesis A4V04_RS13230 a584f69bf7f5f13d3d50f69f0da9ccf3 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 8.8E-54 T 26-04-2017 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0016226|GO:0051536 A4V04_RS13230 a584f69bf7f5f13d3d50f69f0da9ccf3 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 26-04-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site A4V04_RS13230 a584f69bf7f5f13d3d50f69f0da9ccf3 107 Gene3D G3DSA:2.60.300.12 2 96 1.8E-35 T 26-04-2017 IPR000361 FeS cluster biogenesis A4V04_RS02540 3c3ccffbd2aada7eef75b0074207a7d2 322 Gene3D G3DSA:3.40.190.10 174 264 1.4E-11 T 26-04-2017 A4V04_RS02540 3c3ccffbd2aada7eef75b0074207a7d2 322 SUPERFAMILY SSF46785 4 88 3.47E-13 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02540 3c3ccffbd2aada7eef75b0074207a7d2 322 Gene3D G3DSA:1.10.10.10 4 87 5.3E-16 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02540 3c3ccffbd2aada7eef75b0074207a7d2 322 Gene3D G3DSA:3.40.190.10 114 173 3.1E-8 T 26-04-2017 A4V04_RS02540 3c3ccffbd2aada7eef75b0074207a7d2 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 60 1.0E-10 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS02540 3c3ccffbd2aada7eef75b0074207a7d2 322 Pfam PF03466 LysR substrate binding domain 113 295 8.8E-14 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS02540 3c3ccffbd2aada7eef75b0074207a7d2 322 SUPERFAMILY SSF53850 108 298 2.35E-20 T 26-04-2017 A4V04_RS01295 3803a4e8ec2f342a3798ba8561a8a78f 592 Gene3D G3DSA:1.20.1560.10 12 328 5.2E-54 T 26-04-2017 A4V04_RS01295 3803a4e8ec2f342a3798ba8561a8a78f 592 SUPERFAMILY SSF90123 9 328 1.29E-61 T 26-04-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4V04_RS01295 3803a4e8ec2f342a3798ba8561a8a78f 592 SUPERFAMILY SSF52540 332 578 1.11E-91 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01295 3803a4e8ec2f342a3798ba8561a8a78f 592 SMART SM00382 366 553 1.9E-14 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS01295 3803a4e8ec2f342a3798ba8561a8a78f 592 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 12 580 4.6E-210 T 26-04-2017 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 A4V04_RS01295 3803a4e8ec2f342a3798ba8561a8a78f 592 Gene3D G3DSA:3.40.50.300 340 572 5.2E-79 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01295 3803a4e8ec2f342a3798ba8561a8a78f 592 Pfam PF00005 ABC transporter 357 507 3.6E-33 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS01295 3803a4e8ec2f342a3798ba8561a8a78f 592 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS01295 3803a4e8ec2f342a3798ba8561a8a78f 592 Pfam PF00664 ABC transporter transmembrane region 27 292 4.4E-34 T 26-04-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 Pfam PF00012 Hsp70 protein 4 604 1.8E-259 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 Gene3D G3DSA:3.30.420.40 194 231 1.3E-31 T 26-04-2017 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 Gene3D G3DSA:3.30.420.40 321 363 1.3E-31 T 26-04-2017 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 Gene3D G3DSA:3.90.640.10 232 317 4.9E-31 T 26-04-2017 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 339 353 - T 26-04-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 SUPERFAMILY SSF100934 537 612 9.02E-5 T 26-04-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 Gene3D G3DSA:2.60.34.10 392 533 1.2E-72 T 26-04-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 SUPERFAMILY SSF100920 386 542 1.57E-61 T 26-04-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 SUPERFAMILY SSF53067 2 184 4.53E-64 T 26-04-2017 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 194 207 - T 26-04-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 SUPERFAMILY SSF53067 189 384 8.03E-68 T 26-04-2017 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 Gene3D G3DSA:3.30.420.40 4 52 1.2E-61 T 26-04-2017 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 Gene3D G3DSA:3.30.420.40 120 193 1.2E-61 T 26-04-2017 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 Gene3D G3DSA:1.20.1270.10 534 604 3.5E-21 T 26-04-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 Gene3D G3DSA:3.30.30.30 53 106 1.4E-26 T 26-04-2017 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 637 36.391 T 26-04-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 26-04-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 PRINTS PR00301 70kDa heat shock protein signature 471 487 7.9E-78 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 PRINTS PR00301 70kDa heat shock protein signature 367 387 7.9E-78 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 PRINTS PR00301 70kDa heat shock protein signature 139 159 7.9E-78 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 PRINTS PR00301 70kDa heat shock protein signature 390 409 7.9E-78 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 PRINTS PR00301 70kDa heat shock protein signature 31 43 7.9E-78 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 PRINTS PR00301 70kDa heat shock protein signature 54 62 7.9E-78 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 PRINTS PR00301 70kDa heat shock protein signature 200 210 7.9E-78 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 PRINTS PR00301 70kDa heat shock protein signature 336 352 7.9E-78 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 PRINTS PR00301 70kDa heat shock protein signature 3 16 7.9E-78 T 26-04-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4V04_RS08115 339840f16efe9de7e98ab10b6119b65c 637 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 605 6.0E-285 T 26-04-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 A4V04_RS03850 cce291eccd3a29523fc8fd635624b109 519 Pfam PF08502 LeuA allosteric (dimerisation) domain 374 501 7.8E-32 T 26-04-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4V04_RS03850 cce291eccd3a29523fc8fd635624b109 519 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 14 30 - T 26-04-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4V04_RS03850 cce291eccd3a29523fc8fd635624b109 519 SUPERFAMILY SSF51569 2 294 9.34E-92 T 26-04-2017 A4V04_RS03850 cce291eccd3a29523fc8fd635624b109 519 Gene3D G3DSA:3.20.20.70 2 349 3.4E-138 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS03850 cce291eccd3a29523fc8fd635624b109 519 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 6 499 9.9E-202 T 26-04-2017 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4V04_RS03850 cce291eccd3a29523fc8fd635624b109 519 SMART SM00917 373 502 3.6E-36 T 26-04-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4V04_RS03850 cce291eccd3a29523fc8fd635624b109 519 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 201 214 - T 26-04-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4V04_RS03850 cce291eccd3a29523fc8fd635624b109 519 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 4 511 41.46 T 26-04-2017 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4V04_RS03850 cce291eccd3a29523fc8fd635624b109 519 SUPERFAMILY SSF110921 391 501 1.57E-25 T 26-04-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4V04_RS03850 cce291eccd3a29523fc8fd635624b109 519 Pfam PF00682 HMGL-like 7 276 2.8E-91 T 26-04-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4V04_RS12370 89a0b7139699e0a842aa6292ec7e17ad 371 SUPERFAMILY SSF53187 297 368 2.04E-44 T 26-04-2017 A4V04_RS12370 89a0b7139699e0a842aa6292ec7e17ad 371 SUPERFAMILY SSF53187 4 185 2.04E-44 T 26-04-2017 A4V04_RS12370 89a0b7139699e0a842aa6292ec7e17ad 371 SUPERFAMILY SSF55031 176 283 6.15E-23 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS12370 89a0b7139699e0a842aa6292ec7e17ad 371 PIRSF PIRSF037238 1 371 1.3E-108 T 26-04-2017 IPR017150 Peptidase M20, glutamate carboxypeptidase A4V04_RS12370 89a0b7139699e0a842aa6292ec7e17ad 371 Gene3D G3DSA:3.40.630.10 285 368 3.7E-41 T 26-04-2017 A4V04_RS12370 89a0b7139699e0a842aa6292ec7e17ad 371 Gene3D G3DSA:3.40.630.10 5 176 3.7E-41 T 26-04-2017 A4V04_RS12370 89a0b7139699e0a842aa6292ec7e17ad 371 Pfam PF01546 Peptidase family M20/M25/M40 72 368 7.0E-24 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS12370 89a0b7139699e0a842aa6292ec7e17ad 371 Gene3D G3DSA:3.30.70.360 177 279 1.8E-24 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS12370 89a0b7139699e0a842aa6292ec7e17ad 371 Pfam PF07687 Peptidase dimerisation domain 174 253 1.0E-17 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS00770 8f08a053b489a2cfbaf30aad16085fa7 63 Pfam PF03966 Trm112p-like protein 2 41 1.0E-7 T 26-04-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 A4V04_RS00770 8f08a053b489a2cfbaf30aad16085fa7 63 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 23.141 T 26-04-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 A4V04_RS00770 8f08a053b489a2cfbaf30aad16085fa7 63 Gene3D G3DSA:2.20.25.10 8 60 2.8E-21 T 26-04-2017 A4V04_RS00770 8f08a053b489a2cfbaf30aad16085fa7 63 SUPERFAMILY SSF158997 2 58 1.96E-17 T 26-04-2017 A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 PRINTS PR00315 GTP-binding elongation factor signature 7 20 7.9E-15 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 PRINTS PR00315 GTP-binding elongation factor signature 71 81 7.9E-15 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 PRINTS PR00315 GTP-binding elongation factor signature 87 98 7.9E-15 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 PRINTS PR00315 GTP-binding elongation factor signature 51 59 7.9E-15 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 PRINTS PR00315 GTP-binding elongation factor signature 123 132 7.9E-15 T 26-04-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 SUPERFAMILY SSF54980 307 392 1.12E-13 T 26-04-2017 IPR009022 Elongation factor G, III-V domain A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 SUPERFAMILY SSF50447 151 304 5.65E-32 T 26-04-2017 IPR009000 Translation protein, beta-barrel domain A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 Gene3D G3DSA:3.30.70.870 309 404 4.3E-38 T 26-04-2017 A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 604 6.2E-286 T 26-04-2017 IPR006298 GTP-binding protein TypA GO:0005525 A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 Pfam PF00679 Elongation factor G C-terminus 401 482 4.1E-25 T 26-04-2017 IPR000640 Translation elongation factor EFG, V domain A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 Pfam PF00009 Elongation factor Tu GTP binding domain 4 199 2.1E-56 T 26-04-2017 A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 Gene3D G3DSA:3.30.70.240 405 482 7.4E-34 T 26-04-2017 IPR000640 Translation elongation factor EFG, V domain A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 SUPERFAMILY SSF52540 3 210 7.9E-58 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 Gene3D G3DSA:3.40.50.300 3 209 4.6E-66 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 26-04-2017 IPR031157 Tr-type G domain, conserved site A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 Gene3D G3DSA:2.40.30.10 210 308 6.6E-27 T 26-04-2017 A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 SMART SM00838 400 488 4.7E-4 T 26-04-2017 IPR000640 Translation elongation factor EFG, V domain A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 Gene3D G3DSA:2.40.50.250 488 582 7.5E-39 T 26-04-2017 A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 SUPERFAMILY SSF54980 403 518 6.23E-29 T 26-04-2017 IPR009022 Elongation factor G, III-V domain A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 139 2.3E-24 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS02735 37e091421ac673a643548bc03434e31f 616 Pfam PF03144 Elongation factor Tu domain 2 223 294 3.7E-11 T 26-04-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4V04_RS02910 24f9b03e0b3aad79c1177a1f8f500e22 226 ProSitePatterns PS00517 Ribonuclease III family signature. 36 44 - T 26-04-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A4V04_RS02910 24f9b03e0b3aad79c1177a1f8f500e22 226 Gene3D G3DSA:1.10.1520.10 4 146 3.3E-46 T 26-04-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A4V04_RS02910 24f9b03e0b3aad79c1177a1f8f500e22 226 SMART SM00358 154 222 1.7E-16 T 26-04-2017 IPR014720 Double-stranded RNA-binding domain A4V04_RS02910 24f9b03e0b3aad79c1177a1f8f500e22 226 Pfam PF14622 Ribonuclease-III-like 17 136 1.9E-31 T 26-04-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A4V04_RS02910 24f9b03e0b3aad79c1177a1f8f500e22 226 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 7 219 2.2E-67 T 26-04-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A4V04_RS02910 24f9b03e0b3aad79c1177a1f8f500e22 226 Pfam PF00035 Double-stranded RNA binding motif 154 218 2.1E-11 T 26-04-2017 IPR014720 Double-stranded RNA-binding domain A4V04_RS02910 24f9b03e0b3aad79c1177a1f8f500e22 226 SMART SM00535 19 147 2.1E-41 T 26-04-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A4V04_RS02910 24f9b03e0b3aad79c1177a1f8f500e22 226 SUPERFAMILY SSF69065 3 144 5.58E-43 T 26-04-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A4V04_RS02910 24f9b03e0b3aad79c1177a1f8f500e22 226 Hamap MF_00104 Ribonuclease 3 [rnc]. 7 218 28.034 T 26-04-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A4V04_RS02910 24f9b03e0b3aad79c1177a1f8f500e22 226 SUPERFAMILY SSF54768 108 221 5.81E-23 T 26-04-2017 A4V04_RS02910 24f9b03e0b3aad79c1177a1f8f500e22 226 Gene3D G3DSA:3.30.160.20 153 219 2.3E-22 T 26-04-2017 IPR014720 Double-stranded RNA-binding domain A4V04_RS09300 5094db4848f4147b450584e969d4b3b2 302 PIRSF PIRSF026649 1 299 1.6E-77 T 26-04-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 A4V04_RS09300 5094db4848f4147b450584e969d4b3b2 302 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 27 290 3.7E-57 T 26-04-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 A4V04_RS01095 1c20788ee93d1782fdd9450518627257 300 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 289 7.3E-16 T 26-04-2017 IPR020801 Polyketide synthase, acyl transferase domain A4V04_RS01095 1c20788ee93d1782fdd9450518627257 300 Pfam PF00698 Acyl transferase domain 48 292 1.0E-18 T 26-04-2017 IPR014043 Acyl transferase A4V04_RS01095 1c20788ee93d1782fdd9450518627257 300 Gene3D G3DSA:3.40.366.10 184 288 1.3E-43 T 26-04-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 A4V04_RS01095 1c20788ee93d1782fdd9450518627257 300 Gene3D G3DSA:3.40.366.10 2 114 1.3E-43 T 26-04-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 A4V04_RS01095 1c20788ee93d1782fdd9450518627257 300 SUPERFAMILY SSF52151 3 120 4.01E-44 T 26-04-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A4V04_RS01095 1c20788ee93d1782fdd9450518627257 300 SUPERFAMILY SSF52151 185 284 4.01E-44 T 26-04-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A4V04_RS01095 1c20788ee93d1782fdd9450518627257 300 SUPERFAMILY SSF55048 121 177 1.23E-11 T 26-04-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 A4V04_RS01095 1c20788ee93d1782fdd9450518627257 300 Gene3D G3DSA:3.30.70.250 122 183 2.1E-14 T 26-04-2017 A4V04_RS10150 c67473e8e41cb19e77aba3e467949c56 636 SUPERFAMILY SSF53850 122 331 8.86E-16 T 26-04-2017 A4V04_RS10150 c67473e8e41cb19e77aba3e467949c56 636 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 527 633 6.2E-10 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10150 c67473e8e41cb19e77aba3e467949c56 636 SUPERFAMILY SSF55874 479 632 3.93E-22 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10150 c67473e8e41cb19e77aba3e467949c56 636 Gene3D G3DSA:3.30.565.10 486 633 4.8E-23 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10150 c67473e8e41cb19e77aba3e467949c56 636 SMART SM00387 524 634 6.7E-15 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10150 c67473e8e41cb19e77aba3e467949c56 636 Pfam PF00512 His Kinase A (phospho-acceptor) domain 414 480 7.0E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10150 c67473e8e41cb19e77aba3e467949c56 636 SMART SM00388 412 482 1.6E-8 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10150 c67473e8e41cb19e77aba3e467949c56 636 SUPERFAMILY SSF47384 406 480 1.14E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10150 c67473e8e41cb19e77aba3e467949c56 636 Gene3D G3DSA:1.10.287.130 412 478 1.3E-6 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10150 c67473e8e41cb19e77aba3e467949c56 636 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 122 310 2.8E-19 T 26-04-2017 A4V04_RS10150 c67473e8e41cb19e77aba3e467949c56 636 PRINTS PR00344 Bacterial sensor protein C-terminal signature 594 612 4.6E-6 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS10150 c67473e8e41cb19e77aba3e467949c56 636 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 579 4.6E-6 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS07000 f868792975fc51a364799014942bda64 270 SMART SM00382 35 215 1.0E-14 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS07000 f868792975fc51a364799014942bda64 270 SUPERFAMILY SSF52540 25 222 3.22E-64 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07000 f868792975fc51a364799014942bda64 270 Pfam PF00005 ABC transporter 27 165 4.0E-29 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS07000 f868792975fc51a364799014942bda64 270 Gene3D G3DSA:3.40.50.300 2 214 2.1E-65 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07000 f868792975fc51a364799014942bda64 270 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS12825 a41b209c7b137a59eeb392e7d5c3eb6b 258 Gene3D G3DSA:3.40.50.300 4 249 5.8E-39 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12825 a41b209c7b137a59eeb392e7d5c3eb6b 258 SUPERFAMILY SSF52540 5 249 7.63E-30 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12825 a41b209c7b137a59eeb392e7d5c3eb6b 258 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 224 7.0E-22 T 26-04-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A4V04_RS12825 a41b209c7b137a59eeb392e7d5c3eb6b 258 PIRSF PIRSF005647 5 257 1.8E-56 T 26-04-2017 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type A4V04_RS10225 9de6768526be50979b10bed8d5b7bc76 296 Gene3D G3DSA:3.30.70.890 172 294 1.4E-27 T 26-04-2017 IPR013750 GHMP kinase, C-terminal domain A4V04_RS10225 9de6768526be50979b10bed8d5b7bc76 296 SUPERFAMILY SSF55060 173 293 1.34E-20 T 26-04-2017 IPR013750 GHMP kinase, C-terminal domain A4V04_RS10225 9de6768526be50979b10bed8d5b7bc76 296 PIRSF PIRSF010376 15 295 1.5E-80 T 26-04-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A4V04_RS10225 9de6768526be50979b10bed8d5b7bc76 296 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 19 291 2.3E-70 T 26-04-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A4V04_RS10225 9de6768526be50979b10bed8d5b7bc76 296 SUPERFAMILY SSF54211 19 168 1.14E-43 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS10225 9de6768526be50979b10bed8d5b7bc76 296 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 17 288 30.157 T 26-04-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A4V04_RS10225 9de6768526be50979b10bed8d5b7bc76 296 Gene3D G3DSA:3.30.230.10 19 170 1.2E-51 T 26-04-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4V04_RS10225 9de6768526be50979b10bed8d5b7bc76 296 Pfam PF00288 GHMP kinases N terminal domain 97 154 8.8E-12 T 26-04-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 A4V04_RS06725 4108abcedcde97e2ca2ce4c6d4e828e5 298 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 10 123 3.5E-19 T 26-04-2017 IPR017560 Cytochrome c-type biogenesis protein CcmI A4V04_RS06725 4108abcedcde97e2ca2ce4c6d4e828e5 298 SMART SM00028 241 274 0.0076 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS06725 4108abcedcde97e2ca2ce4c6d4e828e5 298 SMART SM00028 167 200 0.089 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS06725 4108abcedcde97e2ca2ce4c6d4e828e5 298 Pfam PF13181 Tetratricopeptide repeat 244 274 0.16 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS06725 4108abcedcde97e2ca2ce4c6d4e828e5 298 Pfam PF13181 Tetratricopeptide repeat 168 199 1.8E-4 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS06725 4108abcedcde97e2ca2ce4c6d4e828e5 298 SUPERFAMILY SSF48452 154 290 4.83E-20 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS06725 4108abcedcde97e2ca2ce4c6d4e828e5 298 Gene3D G3DSA:1.25.40.10 137 289 8.0E-21 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS02510 c0106353a9be7d43517b2f69a79db112 129 Pfam PF01230 HIT domain 23 109 8.8E-24 T 26-04-2017 IPR001310 Histidine triad (HIT) protein A4V04_RS02510 c0106353a9be7d43517b2f69a79db112 129 ProSitePatterns PS00892 HIT domain signature. 88 106 - T 26-04-2017 IPR019808 Histidine triad, conserved site A4V04_RS02510 c0106353a9be7d43517b2f69a79db112 129 Gene3D G3DSA:3.30.428.10 8 121 4.0E-36 T 26-04-2017 IPR011146 HIT-like domain GO:0003824 A4V04_RS02510 c0106353a9be7d43517b2f69a79db112 129 SUPERFAMILY SSF54197 6 119 4.18E-37 T 26-04-2017 IPR011146 HIT-like domain GO:0003824 A4V04_RS02510 c0106353a9be7d43517b2f69a79db112 129 PRINTS PR00332 Histidine triad family signature 95 105 3.5E-7 T 26-04-2017 IPR001310 Histidine triad (HIT) protein A4V04_RS02510 c0106353a9be7d43517b2f69a79db112 129 PRINTS PR00332 Histidine triad family signature 28 46 3.5E-7 T 26-04-2017 IPR001310 Histidine triad (HIT) protein A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 ProSitePatterns PS01244 Aconitase family signature 2. 403 416 - T 26-04-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 Pfam PF00330 Aconitase family (aconitate hydratase) 9 461 2.1E-129 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 ProSitePatterns PS00450 Aconitase family signature 1. 343 359 - T 26-04-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 Gene3D G3DSA:3.40.1060.10 170 284 1.6E-32 T 26-04-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 Gene3D G3DSA:3.30.499.10 335 468 4.6E-56 T 26-04-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 SUPERFAMILY SSF53732 3 468 3.4E-140 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 PRINTS PR00415 Aconitase family signature 199 212 3.2E-35 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 PRINTS PR00415 Aconitase family signature 290 304 3.2E-35 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 PRINTS PR00415 Aconitase family signature 137 152 3.2E-35 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 PRINTS PR00415 Aconitase family signature 123 136 3.2E-35 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 PRINTS PR00415 Aconitase family signature 213 226 3.2E-35 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 PRINTS PR00415 Aconitase family signature 403 416 3.2E-35 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 PRINTS PR00415 Aconitase family signature 86 99 3.2E-35 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 PRINTS PR00415 Aconitase family signature 347 358 3.2E-35 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 468 7.1E-172 T 26-04-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A4V04_RS12095 a4c1f3f2a6bb47ed4fcbc3d323ea3942 469 Gene3D G3DSA:3.30.499.10 3 163 1.2E-18 T 26-04-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 SUPERFAMILY SSF56059 128 401 7.6E-112 T 26-04-2017 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 Gene3D G3DSA:3.40.50.20 534 657 1.4E-63 T 26-04-2017 IPR016185 Pre-ATP-grasp domain A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 26-04-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 Gene3D G3DSA:3.30.1490.20 143 200 1.4E-24 T 26-04-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 Gene3D G3DSA:3.30.470.20 740 934 3.6E-75 T 26-04-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 Gene3D G3DSA:3.30.470.20 201 399 1.1E-79 T 26-04-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 Gene3D G3DSA:3.30.1490.20 682 739 8.0E-25 T 26-04-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1052 0.0 T 26-04-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 422 542 1.6E-41 T 26-04-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 Gene3D G3DSA:3.40.50.20 3 108 3.0E-45 T 26-04-2017 IPR016185 Pre-ATP-grasp domain A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 Pfam PF02142 MGS-like domain 958 1041 6.3E-16 T 26-04-2017 IPR011607 Methylglyoxal synthase-like domain A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 SUPERFAMILY SSF52335 938 1070 9.81E-35 T 26-04-2017 IPR011607 Methylglyoxal synthase-like domain A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 668 875 6.5E-34 T 26-04-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 6.9E-72 T 26-04-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 Gene3D G3DSA:3.40.50.1380 938 1071 1.6E-37 T 26-04-2017 IPR011607 Methylglyoxal synthase-like domain A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 838 845 - T 26-04-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 SMART SM01096 419 542 1.2E-76 T 26-04-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.8E-66 T 26-04-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 1.8E-66 T 26-04-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.8E-66 T 26-04-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.8E-66 T 26-04-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.8E-66 T 26-04-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 1.8E-66 T 26-04-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.8E-66 T 26-04-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 SUPERFAMILY SSF48108 396 549 4.32E-55 T 26-04-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 SUPERFAMILY SSF52440 1 127 1.58E-49 T 26-04-2017 IPR016185 Pre-ATP-grasp domain A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 Gene3D G3DSA:1.10.1030.10 400 533 1.3E-53 T 26-04-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 SUPERFAMILY SSF56059 668 933 2.65E-99 T 26-04-2017 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 704 718 - T 26-04-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 SUPERFAMILY SSF52440 551 670 2.45E-50 T 26-04-2017 IPR016185 Pre-ATP-grasp domain A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 SMART SM00851 955 1042 3.1E-20 T 26-04-2017 IPR011607 Methylglyoxal synthase-like domain A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1068 13.484 T 26-04-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS06945 69091bb6d1605db7e4e8208096e0d775 1073 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1063 13.164 T 26-04-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4V04_RS00810 bbe5df3ea8f7aa6e63b877201490f262 148 Gene3D G3DSA:2.70.40.10 2 147 1.8E-53 T 26-04-2017 IPR029054 dUTPase-like A4V04_RS00810 bbe5df3ea8f7aa6e63b877201490f262 148 Pfam PF00692 dUTPase 17 146 2.6E-38 T 26-04-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 A4V04_RS00810 bbe5df3ea8f7aa6e63b877201490f262 148 TIGRFAM TIGR00576 dut: dUTP diphosphatase 13 146 1.7E-48 T 26-04-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 A4V04_RS00810 bbe5df3ea8f7aa6e63b877201490f262 148 SUPERFAMILY SSF51283 4 147 1.96E-52 T 26-04-2017 IPR029054 dUTPase-like A4V04_RS00810 bbe5df3ea8f7aa6e63b877201490f262 148 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 1 147 31.838 T 26-04-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 SUPERFAMILY SSF56770 48 308 3.92E-86 T 26-04-2017 A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 186 209 4.1E-111 T 26-04-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 68 92 4.1E-111 T 26-04-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 45 67 4.1E-111 T 26-04-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 230 248 4.1E-111 T 26-04-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 114 137 4.1E-111 T 26-04-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 212 229 4.1E-111 T 26-04-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 254 280 4.1E-111 T 26-04-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 157 181 4.1E-111 T 26-04-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 282 295 4.1E-111 T 26-04-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 Gene3D G3DSA:4.10.480.10 225 308 2.5E-38 T 26-04-2017 IPR027394 Cytochrome-c3 hydrogenase, C-terminal A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 14 43 5.1E-6 T 26-04-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 3 356 1.6E-157 T 26-04-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 PIRSF PIRSF000310 3 360 4.5E-137 T 26-04-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 225 306 1.0E-32 T 26-04-2017 IPR027394 Cytochrome-c3 hydrogenase, C-terminal A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 60 205 1.2E-28 T 26-04-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS06785 1684d44c15e9f5c375c0625183ccee3f 366 Gene3D G3DSA:3.40.50.700 48 224 7.4E-55 T 26-04-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS04935 6c466f0cf5995efbdab1398a8d1ffeb4 328 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 11 324 1.9E-61 T 26-04-2017 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 A4V04_RS04935 6c466f0cf5995efbdab1398a8d1ffeb4 328 Gene3D G3DSA:1.10.8.60 139 217 5.0E-29 T 26-04-2017 A4V04_RS04935 6c466f0cf5995efbdab1398a8d1ffeb4 328 Gene3D G3DSA:1.20.272.20 218 325 1.5E-15 T 26-04-2017 A4V04_RS04935 6c466f0cf5995efbdab1398a8d1ffeb4 328 SUPERFAMILY SSF48019 207 324 1.19E-13 T 26-04-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A4V04_RS04935 6c466f0cf5995efbdab1398a8d1ffeb4 328 SUPERFAMILY SSF52540 11 205 3.34E-30 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04935 6c466f0cf5995efbdab1398a8d1ffeb4 328 Pfam PF06144 DNA polymerase III, delta subunit 16 185 5.8E-25 T 26-04-2017 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 A4V04_RS04935 6c466f0cf5995efbdab1398a8d1ffeb4 328 Gene3D G3DSA:3.40.50.300 10 133 6.7E-29 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09760 d4f100959dc29c6c72dc0cf42713dd19 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 68 2.8E-16 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09760 d4f100959dc29c6c72dc0cf42713dd19 324 SUPERFAMILY SSF46785 13 117 5.13E-16 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09760 d4f100959dc29c6c72dc0cf42713dd19 324 Gene3D G3DSA:3.40.190.10 98 229 2.6E-9 T 26-04-2017 A4V04_RS09760 d4f100959dc29c6c72dc0cf42713dd19 324 Pfam PF03466 LysR substrate binding domain 94 283 8.1E-17 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS09760 d4f100959dc29c6c72dc0cf42713dd19 324 SUPERFAMILY SSF53850 94 300 1.71E-18 T 26-04-2017 A4V04_RS09760 d4f100959dc29c6c72dc0cf42713dd19 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 3.2E-6 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09760 d4f100959dc29c6c72dc0cf42713dd19 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 3.2E-6 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09760 d4f100959dc29c6c72dc0cf42713dd19 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 3.2E-6 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09760 d4f100959dc29c6c72dc0cf42713dd19 324 Gene3D G3DSA:1.10.10.10 13 84 2.8E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS00680 9a9455c2b37b33f6dbac223d79e386de 315 Gene3D G3DSA:3.40.630.10 34 135 1.7E-15 T 26-04-2017 A4V04_RS00680 9a9455c2b37b33f6dbac223d79e386de 315 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 37 310 3.1E-31 T 26-04-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 A4V04_RS00680 9a9455c2b37b33f6dbac223d79e386de 315 SUPERFAMILY SSF53187 33 313 1.06E-49 T 26-04-2017 A4V04_RS05450 620d274d39a92717e65628d2d33f8956 409 Pfam PF04165 Protein of unknown function (DUF401) 52 393 2.0E-27 T 26-04-2017 IPR007294 Protein of unknown function DUF401 A4V04_RS05950 939684414aebbae05b733d25c5249568 139 Pfam PF14489 QueF-like protein 40 118 1.1E-31 T 26-04-2017 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A4V04_RS05950 939684414aebbae05b733d25c5249568 139 PIRSF PIRSF027377 1 125 2.0E-54 T 26-04-2017 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A4V04_RS05950 939684414aebbae05b733d25c5249568 139 Gene3D G3DSA:3.30.1130.10 4 122 9.2E-46 T 26-04-2017 A4V04_RS05950 939684414aebbae05b733d25c5249568 139 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 7 117 1.7E-52 T 26-04-2017 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A4V04_RS05950 939684414aebbae05b733d25c5249568 139 SUPERFAMILY SSF55620 4 111 1.41E-27 T 26-04-2017 A4V04_RS05950 939684414aebbae05b733d25c5249568 139 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 139 51.452 T 26-04-2017 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A4V04_RS01570 777f566d1222bb1be410c8868c17ab86 271 Pfam PF13411 MerR HTH family regulatory protein 3 67 2.6E-8 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS01570 777f566d1222bb1be410c8868c17ab86 271 Gene3D G3DSA:1.10.1660.10 3 104 7.4E-19 T 26-04-2017 A4V04_RS01570 777f566d1222bb1be410c8868c17ab86 271 SUPERFAMILY SSF46955 3 109 4.4E-18 T 26-04-2017 IPR009061 Putative DNA-binding domain A4V04_RS01570 777f566d1222bb1be410c8868c17ab86 271 SMART SM00422 2 71 0.0015 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS00830 ad775ec58b8c47b77dee6c28e92a3ed0 314 SUPERFAMILY SSF82114 173 311 2.62E-39 T 26-04-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A4V04_RS00830 ad775ec58b8c47b77dee6c28e92a3ed0 314 SMART SM00904 182 311 1.7E-50 T 26-04-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A4V04_RS00830 ad775ec58b8c47b77dee6c28e92a3ed0 314 Pfam PF06574 FAD synthetase 11 166 1.5E-51 T 26-04-2017 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS00830 ad775ec58b8c47b77dee6c28e92a3ed0 314 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 310 5.0E-85 T 26-04-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS00830 ad775ec58b8c47b77dee6c28e92a3ed0 314 Gene3D G3DSA:2.40.30.30 187 311 1.9E-36 T 26-04-2017 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 A4V04_RS00830 ad775ec58b8c47b77dee6c28e92a3ed0 314 PIRSF PIRSF004491 1 313 5.7E-99 T 26-04-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS00830 ad775ec58b8c47b77dee6c28e92a3ed0 314 Gene3D G3DSA:3.40.50.620 11 185 2.5E-64 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS00830 ad775ec58b8c47b77dee6c28e92a3ed0 314 Pfam PF01687 Riboflavin kinase 183 310 1.1E-35 T 26-04-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A4V04_RS00830 ad775ec58b8c47b77dee6c28e92a3ed0 314 SUPERFAMILY SSF52374 16 179 3.94E-38 T 26-04-2017 A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 Gene3D G3DSA:2.60.260.20 117 149 9.8E-20 T 26-04-2017 A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 Gene3D G3DSA:2.60.260.20 219 262 9.8E-20 T 26-04-2017 A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 Gene3D G3DSA:1.10.287.110 4 93 1.2E-37 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 Pfam PF00684 DnaJ central domain 155 215 2.6E-14 T 26-04-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 PRINTS PR00625 DnaJ domain signature 44 64 5.2E-32 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 PRINTS PR00625 DnaJ domain signature 9 27 5.2E-32 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 PRINTS PR00625 DnaJ domain signature 27 42 5.2E-32 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 PRINTS PR00625 DnaJ domain signature 64 83 5.2E-32 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 Gene3D G3DSA:2.10.230.10 150 218 1.2E-23 T 26-04-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 ProSitePatterns PS00636 Nt-dnaJ domain signature. 49 68 - T 26-04-2017 IPR018253 DnaJ domain, conserved site A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 SMART SM00271 6 64 4.3E-34 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 SUPERFAMILY SSF57938 142 219 1.31E-21 T 26-04-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 SUPERFAMILY SSF49493 267 352 1.15E-23 T 26-04-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 7 357 3.6E-139 T 26-04-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 Pfam PF01556 DnaJ C terminal domain 128 341 7.7E-43 T 26-04-2017 IPR002939 Chaperone DnaJ, C-terminal A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 SUPERFAMILY SSF46565 4 100 7.98E-36 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 Pfam PF00226 DnaJ domain 7 69 4.0E-30 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 4 381 41.516 T 26-04-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 SUPERFAMILY SSF49493 123 177 9.16E-19 T 26-04-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 SUPERFAMILY SSF49493 221 270 9.16E-19 T 26-04-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4V04_RS08110 3af99b0faa6fd1d6ad713268882e1cc4 383 Gene3D G3DSA:2.60.260.20 264 341 3.6E-24 T 26-04-2017 A4V04_RS04360 8dc2ccb482214246bf8c6ca6b8b3ca0e 536 Gene3D G3DSA:1.20.1550.10 19 93 8.7E-8 T 26-04-2017 IPR023380 Disulphide bond formation protein DsbB-like domain A4V04_RS04360 8dc2ccb482214246bf8c6ca6b8b3ca0e 536 Pfam PF02600 Disulfide bond formation protein DsbB 17 95 1.7E-10 T 26-04-2017 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 A4V04_RS04360 8dc2ccb482214246bf8c6ca6b8b3ca0e 536 SUPERFAMILY SSF101898 276 528 1.39E-5 T 26-04-2017 A4V04_RS04360 8dc2ccb482214246bf8c6ca6b8b3ca0e 536 SUPERFAMILY SSF158442 19 131 2.09E-13 T 26-04-2017 A4V04_RS07245 305e74e97185006f449e89ee40ecc73f 535 Gene3D G3DSA:3.50.50.60 471 530 3.4E-59 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07245 305e74e97185006f449e89ee40ecc73f 535 Gene3D G3DSA:3.50.50.60 30 276 3.4E-59 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07245 305e74e97185006f449e89ee40ecc73f 535 Pfam PF00890 FAD binding domain 46 507 7.1E-42 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS07245 305e74e97185006f449e89ee40ecc73f 535 SUPERFAMILY SSF56425 298 474 3.31E-25 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS07245 305e74e97185006f449e89ee40ecc73f 535 Gene3D G3DSA:3.90.700.10 298 466 2.0E-24 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS07245 305e74e97185006f449e89ee40ecc73f 535 SUPERFAMILY SSF51905 37 292 3.45E-36 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07245 305e74e97185006f449e89ee40ecc73f 535 SUPERFAMILY SSF51905 474 530 3.45E-36 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10475 eaba94af579d85baed7e313126c199af 372 Gene3D G3DSA:3.10.150.10 131 254 8.5E-31 T 26-04-2017 A4V04_RS10475 eaba94af579d85baed7e313126c199af 372 Gene3D G3DSA:3.10.150.10 13 122 2.3E-20 T 26-04-2017 A4V04_RS10475 eaba94af579d85baed7e313126c199af 372 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 12 123 1.9E-23 T 26-04-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS10475 eaba94af579d85baed7e313126c199af 372 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 252 371 4.5E-30 T 26-04-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS10475 eaba94af579d85baed7e313126c199af 372 SUPERFAMILY SSF55979 251 372 1.62E-34 T 26-04-2017 A4V04_RS10475 eaba94af579d85baed7e313126c199af 372 PIRSF PIRSF000804 7 372 8.1E-98 T 26-04-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS10475 eaba94af579d85baed7e313126c199af 372 Gene3D G3DSA:3.10.150.10 255 372 2.7E-34 T 26-04-2017 A4V04_RS10475 eaba94af579d85baed7e313126c199af 372 SMART SM00480 21 368 7.8E-108 T 26-04-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS10475 eaba94af579d85baed7e313126c199af 372 SUPERFAMILY SSF55979 15 121 7.49E-17 T 26-04-2017 A4V04_RS10475 eaba94af579d85baed7e313126c199af 372 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 13 371 2.0E-88 T 26-04-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS10475 eaba94af579d85baed7e313126c199af 372 Pfam PF02767 DNA polymerase III beta subunit, central domain 138 249 1.0E-28 T 26-04-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS10475 eaba94af579d85baed7e313126c199af 372 SUPERFAMILY SSF55979 132 250 9.42E-24 T 26-04-2017 A4V04_RS11020 ea995af53c089bdff766ce60677f64af 410 Pfam PF00375 Sodium:dicarboxylate symporter family 17 396 2.7E-66 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11020 ea995af53c089bdff766ce60677f64af 410 PRINTS PR00173 Glutamate-aspartate symporter signature 324 343 1.3E-17 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11020 ea995af53c089bdff766ce60677f64af 410 PRINTS PR00173 Glutamate-aspartate symporter signature 222 241 1.3E-17 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11020 ea995af53c089bdff766ce60677f64af 410 PRINTS PR00173 Glutamate-aspartate symporter signature 289 315 1.3E-17 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11020 ea995af53c089bdff766ce60677f64af 410 PRINTS PR00173 Glutamate-aspartate symporter signature 187 206 1.3E-17 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11020 ea995af53c089bdff766ce60677f64af 410 PRINTS PR00173 Glutamate-aspartate symporter signature 15 35 1.3E-17 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11020 ea995af53c089bdff766ce60677f64af 410 Gene3D G3DSA:1.10.3860.10 12 406 6.3E-84 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11020 ea995af53c089bdff766ce60677f64af 410 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 5 406 34.656 T 26-04-2017 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 A4V04_RS11020 ea995af53c089bdff766ce60677f64af 410 SUPERFAMILY SSF118215 17 399 2.09E-93 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS08715 03f5a7ab050837b69f2a17aa6fb9011b 546 Gene3D G3DSA:1.20.200.10 226 545 1.1E-66 T 26-04-2017 A4V04_RS08715 03f5a7ab050837b69f2a17aa6fb9011b 546 Pfam PF00221 Aromatic amino acid lyase 30 521 4.9E-124 T 26-04-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 A4V04_RS08715 03f5a7ab050837b69f2a17aa6fb9011b 546 Gene3D G3DSA:1.10.275.10 23 223 2.1E-51 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS08715 03f5a7ab050837b69f2a17aa6fb9011b 546 SUPERFAMILY SSF48557 21 544 1.41E-126 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS01390 0b95bd29701f92ec0b0bfca4f5ddb2d6 542 SUPERFAMILY SSF53335 19 56 2.66E-114 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS01390 0b95bd29701f92ec0b0bfca4f5ddb2d6 542 SUPERFAMILY SSF53335 98 541 2.66E-114 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS01390 0b95bd29701f92ec0b0bfca4f5ddb2d6 542 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 295 307 1.2E-12 T 26-04-2017 A4V04_RS01390 0b95bd29701f92ec0b0bfca4f5ddb2d6 542 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 198 214 1.2E-12 T 26-04-2017 A4V04_RS01390 0b95bd29701f92ec0b0bfca4f5ddb2d6 542 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 221 235 1.2E-12 T 26-04-2017 A4V04_RS01390 0b95bd29701f92ec0b0bfca4f5ddb2d6 542 Gene3D G3DSA:3.40.50.150 176 388 1.2E-31 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS01390 0b95bd29701f92ec0b0bfca4f5ddb2d6 542 Pfam PF02384 N-6 DNA Methylase 174 499 1.5E-89 T 26-04-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A4V04_RS01390 0b95bd29701f92ec0b0bfca4f5ddb2d6 542 Pfam PF12161 HsdM N-terminal domain 19 164 4.4E-14 T 26-04-2017 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain A4V04_RS01045 6dadc3763defc9d54fb94c65d231284a 331 SUPERFAMILY SSF55821 5 208 1.56E-60 T 26-04-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain A4V04_RS01045 6dadc3763defc9d54fb94c65d231284a 331 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 3 207 7.0E-57 T 26-04-2017 IPR006070 YrdC-like domain GO:0003725 A4V04_RS01045 6dadc3763defc9d54fb94c65d231284a 331 PIRSF PIRSF004930 1 331 3.2E-96 T 26-04-2017 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 A4V04_RS01045 6dadc3763defc9d54fb94c65d231284a 331 Pfam PF03481 Putative GTP-binding controlling metal-binding 200 328 2.4E-13 T 26-04-2017 IPR005145 Putative GTP-binding controlling metal-binding domain A4V04_RS01045 6dadc3763defc9d54fb94c65d231284a 331 Pfam PF01300 Telomere recombination 13 196 1.6E-55 T 26-04-2017 IPR006070 YrdC-like domain GO:0003725 A4V04_RS01045 6dadc3763defc9d54fb94c65d231284a 331 Gene3D G3DSA:3.90.870.10 3 203 1.0E-73 T 26-04-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain A4V04_RS13135 743fed844b6b805a5a3c0460ef4b67d3 188 SUPERFAMILY SSF47781 65 133 2.97E-22 T 26-04-2017 IPR010994 RuvA domain 2-like A4V04_RS13135 743fed844b6b805a5a3c0460ef4b67d3 188 SMART SM00278 73 92 0.57 T 26-04-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4V04_RS13135 743fed844b6b805a5a3c0460ef4b67d3 188 SMART SM00278 108 127 0.0057 T 26-04-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4V04_RS13135 743fed844b6b805a5a3c0460ef4b67d3 188 Pfam PF01330 RuvA N terminal domain 2 62 3.0E-20 T 26-04-2017 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 A4V04_RS13135 743fed844b6b805a5a3c0460ef4b67d3 188 Gene3D G3DSA:1.10.150.20 67 136 4.0E-30 T 26-04-2017 A4V04_RS13135 743fed844b6b805a5a3c0460ef4b67d3 188 SUPERFAMILY SSF46929 145 187 8.11E-8 T 26-04-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 A4V04_RS13135 743fed844b6b805a5a3c0460ef4b67d3 188 SUPERFAMILY SSF50249 1 63 2.68E-17 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS13135 743fed844b6b805a5a3c0460ef4b67d3 188 Gene3D G3DSA:2.40.50.140 2 66 4.4E-26 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS13135 743fed844b6b805a5a3c0460ef4b67d3 188 Pfam PF14520 Helix-hairpin-helix domain 72 130 8.8E-20 T 26-04-2017 A4V04_RS13135 743fed844b6b805a5a3c0460ef4b67d3 188 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 186 1.4E-55 T 26-04-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A4V04_RS13135 743fed844b6b805a5a3c0460ef4b67d3 188 Gene3D G3DSA:1.10.8.10 143 186 6.4E-7 T 26-04-2017 A4V04_RS13135 743fed844b6b805a5a3c0460ef4b67d3 188 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 187 31.287 T 26-04-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A4V04_RS13135 743fed844b6b805a5a3c0460ef4b67d3 188 Pfam PF07499 RuvA, C-terminal domain 145 186 5.4E-12 T 26-04-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 A4V04_RS08050 eca39b74647c733b646c6642034f3681 450 Gene3D G3DSA:3.40.50.300 217 375 4.0E-49 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08050 eca39b74647c733b646c6642034f3681 450 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 155 163 - T 26-04-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A4V04_RS08050 eca39b74647c733b646c6642034f3681 450 SMART SM00490 259 340 7.5E-30 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS08050 eca39b74647c733b646c6642034f3681 450 SUPERFAMILY SSF52540 77 361 4.37E-74 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08050 eca39b74647c733b646c6642034f3681 450 Pfam PF00270 DEAD/DEAH box helicase 27 198 6.4E-49 T 26-04-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4V04_RS08050 eca39b74647c733b646c6642034f3681 450 Pfam PF00271 Helicase conserved C-terminal domain 233 340 8.9E-27 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS08050 eca39b74647c733b646c6642034f3681 450 Gene3D G3DSA:3.40.50.300 4 216 2.4E-77 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08050 eca39b74647c733b646c6642034f3681 450 SMART SM00487 22 223 4.0E-60 T 26-04-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4V04_RS11690 0b452b03e652c757ad58cf689786866b 443 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 38 53 - T 26-04-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site A4V04_RS11690 0b452b03e652c757ad58cf689786866b 443 Pfam PF00375 Sodium:dicarboxylate symporter family 11 403 2.4E-113 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11690 0b452b03e652c757ad58cf689786866b 443 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 297 320 - T 26-04-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site A4V04_RS11690 0b452b03e652c757ad58cf689786866b 443 Gene3D G3DSA:1.10.3860.10 8 408 6.1E-116 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11690 0b452b03e652c757ad58cf689786866b 443 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 4 430 36.383 T 26-04-2017 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 A4V04_RS11690 0b452b03e652c757ad58cf689786866b 443 PRINTS PR00173 Glutamate-aspartate symporter signature 194 213 9.7E-35 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11690 0b452b03e652c757ad58cf689786866b 443 PRINTS PR00173 Glutamate-aspartate symporter signature 76 101 9.7E-35 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11690 0b452b03e652c757ad58cf689786866b 443 PRINTS PR00173 Glutamate-aspartate symporter signature 46 66 9.7E-35 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11690 0b452b03e652c757ad58cf689786866b 443 PRINTS PR00173 Glutamate-aspartate symporter signature 329 348 9.7E-35 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11690 0b452b03e652c757ad58cf689786866b 443 PRINTS PR00173 Glutamate-aspartate symporter signature 294 320 9.7E-35 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11690 0b452b03e652c757ad58cf689786866b 443 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 9.7E-35 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11690 0b452b03e652c757ad58cf689786866b 443 PRINTS PR00173 Glutamate-aspartate symporter signature 147 169 9.7E-35 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11690 0b452b03e652c757ad58cf689786866b 443 SUPERFAMILY SSF118215 11 403 2.48E-118 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS00785 bb73d6f21e3efd1bffd7221de315b577 194 Gene3D G3DSA:1.10.287.990 20 83 1.4E-20 T 26-04-2017 A4V04_RS00785 bb73d6f21e3efd1bffd7221de315b577 194 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 158 165 - T 26-04-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4V04_RS00785 bb73d6f21e3efd1bffd7221de315b577 194 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 2.0E-21 T 26-04-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4V04_RS00785 bb73d6f21e3efd1bffd7221de315b577 194 PRINTS PR01703 Manganese superoxide dismutase signature 66 79 2.0E-21 T 26-04-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4V04_RS00785 bb73d6f21e3efd1bffd7221de315b577 194 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.0E-21 T 26-04-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4V04_RS00785 bb73d6f21e3efd1bffd7221de315b577 194 PRINTS PR01703 Manganese superoxide dismutase signature 119 127 2.0E-21 T 26-04-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4V04_RS00785 bb73d6f21e3efd1bffd7221de315b577 194 PRINTS PR01703 Manganese superoxide dismutase signature 156 168 2.0E-21 T 26-04-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4V04_RS00785 bb73d6f21e3efd1bffd7221de315b577 194 SUPERFAMILY SSF46609 1 88 4.58E-34 T 26-04-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4V04_RS00785 bb73d6f21e3efd1bffd7221de315b577 194 SUPERFAMILY SSF54719 85 193 1.57E-39 T 26-04-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4V04_RS00785 bb73d6f21e3efd1bffd7221de315b577 194 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 82 1.6E-30 T 26-04-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4V04_RS00785 bb73d6f21e3efd1bffd7221de315b577 194 PIRSF PIRSF000349 1 194 2.2E-77 T 26-04-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4V04_RS00785 bb73d6f21e3efd1bffd7221de315b577 194 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 90 192 1.3E-34 T 26-04-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 SMART SM01192 139 425 1.2E-221 T 26-04-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 425 4.6E-211 T 26-04-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 Gene3D G3DSA:3.20.20.120 128 425 5.6E-137 T 26-04-2017 IPR029065 Enolase C-terminal domain-like A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 423 7.9E-133 T 26-04-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 SUPERFAMILY SSF54826 3 138 6.46E-57 T 26-04-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 ProSitePatterns PS00164 Enolase signature. 334 347 - T 26-04-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 Gene3D G3DSA:3.30.390.10 4 126 7.5E-56 T 26-04-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 Pfam PF03952 Enolase, N-terminal domain 4 133 4.6E-60 T 26-04-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 PIRSF PIRSF001400 1 425 1.0E-193 T 26-04-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 Hamap MF_00318 Enolase [eno]. 2 411 45.238 T 26-04-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 SUPERFAMILY SSF51604 140 425 3.25E-131 T 26-04-2017 IPR029065 Enolase C-terminal domain-like A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 PRINTS PR00148 Enolase signature 107 123 6.4E-46 T 26-04-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 PRINTS PR00148 Enolase signature 363 380 6.4E-46 T 26-04-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 PRINTS PR00148 Enolase signature 311 322 6.4E-46 T 26-04-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 PRINTS PR00148 Enolase signature 37 51 6.4E-46 T 26-04-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 PRINTS PR00148 Enolase signature 334 348 6.4E-46 T 26-04-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 PRINTS PR00148 Enolase signature 161 174 6.4E-46 T 26-04-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS03200 62ab04d1a5f412dd1660040fa2431afb 428 SMART SM01193 4 134 2.1E-95 T 26-04-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4V04_RS06885 c45079d9eebbf46277adc206e0b18c72 311 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 10 294 27.672 T 26-04-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A4V04_RS06885 c45079d9eebbf46277adc206e0b18c72 311 Gene3D G3DSA:1.20.1640.10 97 297 6.9E-29 T 26-04-2017 A4V04_RS06885 c45079d9eebbf46277adc206e0b18c72 311 SUPERFAMILY SSF82866 74 294 4.32E-40 T 26-04-2017 A4V04_RS06885 c45079d9eebbf46277adc206e0b18c72 311 Pfam PF02355 Protein export membrane protein 109 291 7.9E-63 T 26-04-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A4V04_RS06885 c45079d9eebbf46277adc206e0b18c72 311 PRINTS PR01755 Bacterial translocase SecF protein signature 199 217 8.8E-26 T 26-04-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4V04_RS06885 c45079d9eebbf46277adc206e0b18c72 311 PRINTS PR01755 Bacterial translocase SecF protein signature 151 165 8.8E-26 T 26-04-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4V04_RS06885 c45079d9eebbf46277adc206e0b18c72 311 PRINTS PR01755 Bacterial translocase SecF protein signature 231 246 8.8E-26 T 26-04-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4V04_RS06885 c45079d9eebbf46277adc206e0b18c72 311 PRINTS PR01755 Bacterial translocase SecF protein signature 37 52 8.8E-26 T 26-04-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4V04_RS06885 c45079d9eebbf46277adc206e0b18c72 311 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 38 283 4.0E-75 T 26-04-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A4V04_RS06885 c45079d9eebbf46277adc206e0b18c72 311 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 116 280 2.3E-49 T 26-04-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 Gene3D G3DSA:3.90.960.10 253 397 6.3E-26 T 26-04-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 SUPERFAMILY SSF55826 218 398 2.09E-27 T 26-04-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 SUPERFAMILY SSF52954 472 580 3.93E-32 T 26-04-2017 IPR004154 Anticodon-binding A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 Gene3D G3DSA:3.40.50.800 480 580 4.8E-30 T 26-04-2017 IPR004154 Anticodon-binding A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 PIRSF PIRSF001535 1 581 1.6E-260 T 26-04-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 Pfam PF03129 Anticodon binding domain 485 578 7.6E-19 T 26-04-2017 IPR004154 Anticodon-binding A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.3E-18 T 26-04-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.3E-18 T 26-04-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.3E-18 T 26-04-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.3E-18 T 26-04-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 580 40.206 T 26-04-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 Gene3D G3DSA:3.30.930.10 416 477 1.6E-104 T 26-04-2017 A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 Gene3D G3DSA:3.30.930.10 1 228 1.6E-104 T 26-04-2017 A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 Pfam PF04073 Aminoacyl-tRNA editing domain 257 387 1.6E-22 T 26-04-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 468 6.8E-46 T 26-04-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 577 2.0E-226 T 26-04-2017 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 SUPERFAMILY SSF55681 10 237 1.42E-98 T 26-04-2017 A4V04_RS11640 2f7f77769fe09ec3734cbeb2ce4f74a8 581 SUPERFAMILY SSF55681 416 487 1.42E-98 T 26-04-2017 A4V04_RS05610 cbfa66349c5574a8e0b1a333896c3f7d 429 Gene3D G3DSA:1.10.443.10 221 336 1.8E-12 T 26-04-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS05610 cbfa66349c5574a8e0b1a333896c3f7d 429 SUPERFAMILY SSF56349 99 338 1.06E-32 T 26-04-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4V04_RS05610 cbfa66349c5574a8e0b1a333896c3f7d 429 Gene3D G3DSA:1.10.150.130 99 195 2.7E-8 T 26-04-2017 IPR023109 Integrase/recombinase, N-terminal A4V04_RS05610 cbfa66349c5574a8e0b1a333896c3f7d 429 Pfam PF13356 Domain of unknown function (DUF4102) 6 86 1.2E-12 T 26-04-2017 IPR025166 Domain of unknown function DUF4102 A4V04_RS05610 cbfa66349c5574a8e0b1a333896c3f7d 429 Pfam PF00589 Phage integrase family 220 337 7.5E-8 T 26-04-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS09015 d1177da859b9089c395097b5404d4a35 256 Gene3D G3DSA:3.40.50.300 6 249 1.5E-65 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09015 d1177da859b9089c395097b5404d4a35 256 SUPERFAMILY SSF52540 13 251 1.55E-60 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09015 d1177da859b9089c395097b5404d4a35 256 Pfam PF00005 ABC transporter 29 181 1.0E-34 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS09015 d1177da859b9089c395097b5404d4a35 256 SMART SM00382 38 246 7.4E-10 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS09015 d1177da859b9089c395097b5404d4a35 256 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 14 256 3.5E-111 T 26-04-2017 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 A4V04_RS09015 d1177da859b9089c395097b5404d4a35 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 230 251 2.8E-6 T 26-04-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A4V04_RS11580 54c549de7212f4e5f79d95dfa2a88724 387 Gene3D G3DSA:1.10.490.10 2 142 1.1E-54 T 26-04-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A4V04_RS11580 54c549de7212f4e5f79d95dfa2a88724 387 Pfam PF00042 Globin 6 103 6.9E-12 T 26-04-2017 IPR000971 Globin GO:0019825|GO:0020037 A4V04_RS11580 54c549de7212f4e5f79d95dfa2a88724 387 PRINTS PR00409 Phthalate dioxygenase reductase family signature 247 261 3.9E-9 T 26-04-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4V04_RS11580 54c549de7212f4e5f79d95dfa2a88724 387 PRINTS PR00409 Phthalate dioxygenase reductase family signature 233 247 3.9E-9 T 26-04-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4V04_RS11580 54c549de7212f4e5f79d95dfa2a88724 387 PRINTS PR00409 Phthalate dioxygenase reductase family signature 269 288 3.9E-9 T 26-04-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4V04_RS11580 54c549de7212f4e5f79d95dfa2a88724 387 PRINTS PR00409 Phthalate dioxygenase reductase family signature 350 358 3.9E-9 T 26-04-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4V04_RS11580 54c549de7212f4e5f79d95dfa2a88724 387 Gene3D G3DSA:2.40.30.10 151 259 1.7E-26 T 26-04-2017 A4V04_RS11580 54c549de7212f4e5f79d95dfa2a88724 387 Pfam PF00175 Oxidoreductase NAD-binding domain 270 364 1.0E-10 T 26-04-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4V04_RS11580 54c549de7212f4e5f79d95dfa2a88724 387 Pfam PF00970 Oxidoreductase FAD-binding domain 158 259 1.5E-7 T 26-04-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 A4V04_RS11580 54c549de7212f4e5f79d95dfa2a88724 387 SUPERFAMILY SSF63380 151 259 2.69E-21 T 26-04-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A4V04_RS11580 54c549de7212f4e5f79d95dfa2a88724 387 SUPERFAMILY SSF46458 2 143 2.99E-42 T 26-04-2017 IPR009050 Globin-like A4V04_RS11580 54c549de7212f4e5f79d95dfa2a88724 387 SUPERFAMILY SSF52343 262 383 2.75E-29 T 26-04-2017 A4V04_RS11580 54c549de7212f4e5f79d95dfa2a88724 387 Gene3D G3DSA:3.40.50.80 261 382 2.5E-28 T 26-04-2017 A4V04_RS12535 9fb897e5b894a6e7f373656dfa84653b 275 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 268 18.071 T 26-04-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A4V04_RS12535 9fb897e5b894a6e7f373656dfa84653b 275 Pfam PF02673 Bacitracin resistance protein BacA 9 262 1.7E-82 T 26-04-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A4V04_RS12535 9fb897e5b894a6e7f373656dfa84653b 275 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 261 1.4E-79 T 26-04-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A4V04_RS05240 7f5a18b81b3f68321240e90f8126eaf5 88 Pfam PF01722 BolA-like protein 40 85 7.0E-10 T 26-04-2017 IPR002634 BolA protein A4V04_RS05240 7f5a18b81b3f68321240e90f8126eaf5 88 SUPERFAMILY SSF82657 8 85 1.19E-12 T 26-04-2017 IPR002634 BolA protein A4V04_RS05240 7f5a18b81b3f68321240e90f8126eaf5 88 Gene3D G3DSA:3.30.300.90 8 86 1.8E-10 T 26-04-2017 IPR002634 BolA protein A4V04_RS10110 50cc1cbe2c32f1dae23d82cc9721d538 321 Gene3D G3DSA:1.10.10.10 4 81 1.6E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10110 50cc1cbe2c32f1dae23d82cc9721d538 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 62 3.8E-15 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10110 50cc1cbe2c32f1dae23d82cc9721d538 321 SUPERFAMILY SSF53850 103 299 1.02E-23 T 26-04-2017 A4V04_RS10110 50cc1cbe2c32f1dae23d82cc9721d538 321 SUPERFAMILY SSF46785 3 84 1.39E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10110 50cc1cbe2c32f1dae23d82cc9721d538 321 Pfam PF03466 LysR substrate binding domain 92 296 1.4E-18 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS10110 50cc1cbe2c32f1dae23d82cc9721d538 321 Gene3D G3DSA:3.40.190.10 105 176 4.2E-8 T 26-04-2017 A4V04_RS10110 50cc1cbe2c32f1dae23d82cc9721d538 321 Gene3D G3DSA:3.40.190.10 177 262 9.5E-5 T 26-04-2017 A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 Gene3D G3DSA:3.40.50.20 2 93 2.1E-35 T 26-04-2017 IPR016185 Pre-ATP-grasp domain A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 298 5.3E-79 T 26-04-2017 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 425 42.342 T 26-04-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 SUPERFAMILY SSF56059 102 328 3.36E-62 T 26-04-2017 A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 SUPERFAMILY SSF51246 331 425 7.61E-30 T 26-04-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 SMART SM01209 101 298 2.4E-133 T 26-04-2017 A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 Gene3D G3DSA:3.90.600.10 333 425 6.9E-35 T 26-04-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 425 1.2E-170 T 26-04-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 292 299 - T 26-04-2017 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 2.8E-35 T 26-04-2017 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 SMART SM01210 332 425 2.2E-52 T 26-04-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 Gene3D G3DSA:3.30.1490.20 119 188 9.2E-32 T 26-04-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 Gene3D G3DSA:3.30.470.20 189 330 6.8E-62 T 26-04-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 333 423 3.0E-30 T 26-04-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4V04_RS07950 b1330d20a31a3e937eaf34975433bc5e 425 SUPERFAMILY SSF52440 1 101 8.06E-34 T 26-04-2017 IPR016185 Pre-ATP-grasp domain A4V04_RS04345 0c7277b8f684c7fb6f2a8d5477af3975 331 PRINTS PR00139 Asparaginase/glutaminase family signature 268 286 1.7E-21 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS04345 0c7277b8f684c7fb6f2a8d5477af3975 331 PRINTS PR00139 Asparaginase/glutaminase family signature 9 20 1.7E-21 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS04345 0c7277b8f684c7fb6f2a8d5477af3975 331 PRINTS PR00139 Asparaginase/glutaminase family signature 89 107 1.7E-21 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS04345 0c7277b8f684c7fb6f2a8d5477af3975 331 SMART SM00870 8 325 2.5E-136 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS04345 0c7277b8f684c7fb6f2a8d5477af3975 331 Gene3D G3DSA:3.40.50.40 221 330 1.9E-38 T 26-04-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 A4V04_RS04345 0c7277b8f684c7fb6f2a8d5477af3975 331 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 11 19 - T 26-04-2017 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A4V04_RS04345 0c7277b8f684c7fb6f2a8d5477af3975 331 PIRSF PIRSF001220 3 331 1.4E-89 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS04345 0c7277b8f684c7fb6f2a8d5477af3975 331 Gene3D G3DSA:3.40.50.1170 5 217 4.0E-67 T 26-04-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A4V04_RS04345 0c7277b8f684c7fb6f2a8d5477af3975 331 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 4 331 8.0E-126 T 26-04-2017 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 A4V04_RS04345 0c7277b8f684c7fb6f2a8d5477af3975 331 PIRSF PIRSF500176 5 331 4.7E-76 T 26-04-2017 A4V04_RS04345 0c7277b8f684c7fb6f2a8d5477af3975 331 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 90 100 - T 26-04-2017 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A4V04_RS04345 0c7277b8f684c7fb6f2a8d5477af3975 331 SUPERFAMILY SSF53774 6 330 1.13E-99 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS04345 0c7277b8f684c7fb6f2a8d5477af3975 331 Pfam PF00710 Asparaginase, N-terminal 8 200 8.0E-55 T 26-04-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 SUPERFAMILY SSF51735 1 148 2.83E-30 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 Gene3D G3DSA:3.40.50.720 233 384 1.5E-34 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 Gene3D G3DSA:3.40.50.720 1 148 1.8E-41 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 SUPERFAMILY SSF116726 135 221 3.66E-10 T 26-04-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 Pfam PF02254 TrkA-N domain 3 106 1.6E-24 T 26-04-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 Pfam PF02254 TrkA-N domain 235 358 8.8E-19 T 26-04-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 Gene3D G3DSA:3.30.70.1450 151 218 4.1E-6 T 26-04-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 SUPERFAMILY SSF116726 369 455 8.5E-6 T 26-04-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 Pfam PF02080 TrkA-C domain 397 464 3.0E-8 T 26-04-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 Pfam PF02080 TrkA-C domain 155 225 7.2E-11 T 26-04-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 2.1E-22 T 26-04-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.1E-22 T 26-04-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.1E-22 T 26-04-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.1E-22 T 26-04-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.1E-22 T 26-04-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4V04_RS09955 c7c141e2ee05e67a580eae8ea0dc11b9 471 SUPERFAMILY SSF51735 232 384 1.94E-27 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03820 3414c9ab91431692edca8409218e0c16 119 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 71 2.4E-6 T 26-04-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain A4V04_RS03820 3414c9ab91431692edca8409218e0c16 119 SUPERFAMILY SSF54909 3 98 9.27E-16 T 26-04-2017 IPR011008 Dimeric alpha-beta barrel A4V04_RS03820 3414c9ab91431692edca8409218e0c16 119 Gene3D G3DSA:3.30.70.900 2 99 9.6E-12 T 26-04-2017 A4V04_RS08995 a65531300c98def609a8b3153b6902b8 327 SMART SM00116 213 261 0.0054 T 26-04-2017 IPR000644 CBS domain A4V04_RS08995 a65531300c98def609a8b3153b6902b8 327 Pfam PF01380 SIS domain 43 175 1.6E-34 T 26-04-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4V04_RS08995 a65531300c98def609a8b3153b6902b8 327 Pfam PF00571 CBS domain 272 324 2.4E-5 T 26-04-2017 IPR000644 CBS domain A4V04_RS08995 a65531300c98def609a8b3153b6902b8 327 Pfam PF00571 CBS domain 204 261 8.3E-8 T 26-04-2017 IPR000644 CBS domain A4V04_RS08995 a65531300c98def609a8b3153b6902b8 327 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 48 317 6.7E-108 T 26-04-2017 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 A4V04_RS08995 a65531300c98def609a8b3153b6902b8 327 PIRSF PIRSF004692 2 327 1.1E-128 T 26-04-2017 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 A4V04_RS08995 a65531300c98def609a8b3153b6902b8 327 Gene3D G3DSA:3.40.50.10490 14 197 1.2E-51 T 26-04-2017 A4V04_RS08995 a65531300c98def609a8b3153b6902b8 327 SUPERFAMILY SSF53697 15 325 3.34E-67 T 26-04-2017 A4V04_RS08995 a65531300c98def609a8b3153b6902b8 327 Gene3D G3DSA:3.10.580.10 198 323 1.3E-35 T 26-04-2017 A4V04_RS12005 f75753c79fe5215bae54ab06763ba494 316 Pfam PF07478 D-ala D-ala ligase C-terminus 113 305 3.4E-48 T 26-04-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS12005 f75753c79fe5215bae54ab06763ba494 316 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 9 313 31.777 T 26-04-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS12005 f75753c79fe5215bae54ab06763ba494 316 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 255 283 - T 26-04-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS12005 f75753c79fe5215bae54ab06763ba494 316 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 10 308 3.8E-87 T 26-04-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS12005 f75753c79fe5215bae54ab06763ba494 316 Pfam PF01820 D-ala D-ala ligase N-terminus 10 92 2.6E-20 T 26-04-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS12005 f75753c79fe5215bae54ab06763ba494 316 SUPERFAMILY SSF56059 102 312 8.66E-49 T 26-04-2017 A4V04_RS12005 f75753c79fe5215bae54ab06763ba494 316 Gene3D G3DSA:3.40.50.20 10 90 5.4E-26 T 26-04-2017 IPR016185 Pre-ATP-grasp domain A4V04_RS12005 f75753c79fe5215bae54ab06763ba494 316 PIRSF PIRSF039102 44 315 5.8E-79 T 26-04-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS12005 f75753c79fe5215bae54ab06763ba494 316 Gene3D G3DSA:3.30.470.20 92 115 7.7E-44 T 26-04-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4V04_RS12005 f75753c79fe5215bae54ab06763ba494 316 Gene3D G3DSA:3.30.470.20 186 309 7.7E-44 T 26-04-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4V04_RS12005 f75753c79fe5215bae54ab06763ba494 316 Gene3D G3DSA:3.30.1490.20 116 183 8.5E-14 T 26-04-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4V04_RS12005 f75753c79fe5215bae54ab06763ba494 316 SUPERFAMILY SSF52440 10 102 2.21E-26 T 26-04-2017 IPR016185 Pre-ATP-grasp domain A4V04_RS12005 f75753c79fe5215bae54ab06763ba494 316 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 69 80 - T 26-04-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS11180 5186975fddee6e7a09a3474e087d0374 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.918 T 26-04-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11180 5186975fddee6e7a09a3474e087d0374 103 SUPERFAMILY SSF54999 5 102 4.45E-36 T 26-04-2017 IPR027486 Ribosomal protein S10 domain A4V04_RS11180 5186975fddee6e7a09a3474e087d0374 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 102 5.3E-44 T 26-04-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11180 5186975fddee6e7a09a3474e087d0374 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 1.4E-16 T 26-04-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11180 5186975fddee6e7a09a3474e087d0374 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.4E-16 T 26-04-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11180 5186975fddee6e7a09a3474e087d0374 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 1.4E-16 T 26-04-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11180 5186975fddee6e7a09a3474e087d0374 103 SMART SM01403 7 101 2.5E-53 T 26-04-2017 IPR027486 Ribosomal protein S10 domain A4V04_RS11180 5186975fddee6e7a09a3474e087d0374 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 26-04-2017 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11180 5186975fddee6e7a09a3474e087d0374 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 3.5E-34 T 26-04-2017 IPR027486 Ribosomal protein S10 domain A4V04_RS11180 5186975fddee6e7a09a3474e087d0374 103 Gene3D G3DSA:3.30.70.600 4 102 1.0E-40 T 26-04-2017 IPR027486 Ribosomal protein S10 domain A4V04_RS08350 ef3485c5301744e0bb390182e29265bc 341 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS08350 ef3485c5301744e0bb390182e29265bc 341 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 312 1.8E-19 T 26-04-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4V04_RS08350 ef3485c5301744e0bb390182e29265bc 341 Pfam PF00005 ABC transporter 45 197 1.1E-30 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS08350 ef3485c5301744e0bb390182e29265bc 341 SMART SM00382 53 246 6.2E-12 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS08350 ef3485c5301744e0bb390182e29265bc 341 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 247 325 2.7E-26 T 26-04-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4V04_RS08350 ef3485c5301744e0bb390182e29265bc 341 Gene3D G3DSA:3.40.50.300 12 270 2.1E-74 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08350 ef3485c5301744e0bb390182e29265bc 341 SUPERFAMILY SSF52540 13 267 1.69E-69 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06650 f784ceb7369ad07867469b93d4ce80dd 239 PIRSF PIRSF039085 1 239 3.6E-117 T 26-04-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A4V04_RS06650 f784ceb7369ad07867469b93d4ce80dd 239 Pfam PF00005 ABC transporter 17 164 9.6E-38 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS06650 f784ceb7369ad07867469b93d4ce80dd 239 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS06650 f784ceb7369ad07867469b93d4ce80dd 239 Gene3D G3DSA:3.40.50.300 1 236 8.3E-87 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06650 f784ceb7369ad07867469b93d4ce80dd 239 SUPERFAMILY SSF52540 1 234 2.79E-82 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06650 f784ceb7369ad07867469b93d4ce80dd 239 SMART SM00382 26 211 3.5E-15 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS05420 422bff7e0aa8b69d184e485709285148 154 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 16 148 1.3E-33 T 26-04-2017 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 A4V04_RS05420 422bff7e0aa8b69d184e485709285148 154 Gene3D G3DSA:3.40.630.30 2 151 9.2E-28 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS05420 422bff7e0aa8b69d184e485709285148 154 Pfam PF00583 Acetyltransferase (GNAT) family 54 127 2.0E-12 T 26-04-2017 IPR000182 GNAT domain GO:0008080 A4V04_RS05420 422bff7e0aa8b69d184e485709285148 154 SUPERFAMILY SSF55729 2 150 2.27E-25 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS08935 47690ff3d61feed08f6fe949730f118c 400 Pfam PF07690 Major Facilitator Superfamily 20 291 7.2E-29 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS08935 47690ff3d61feed08f6fe949730f118c 400 SUPERFAMILY SSF103473 5 386 2.09E-50 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS08935 47690ff3d61feed08f6fe949730f118c 400 Gene3D G3DSA:1.20.1250.20 12 191 6.4E-25 T 26-04-2017 A4V04_RS08935 47690ff3d61feed08f6fe949730f118c 400 Gene3D G3DSA:1.20.1250.20 209 389 4.1E-12 T 26-04-2017 A4V04_RS02220 75fbfb81a602bd70bd347d5b65466be9 164 Pfam PF14537 Cytochrome c3 48 125 1.1E-15 T 26-04-2017 A4V04_RS02220 75fbfb81a602bd70bd347d5b65466be9 164 SUPERFAMILY SSF48695 51 131 4.04E-13 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS02220 75fbfb81a602bd70bd347d5b65466be9 164 Gene3D G3DSA:3.90.10.10 37 127 1.0E-10 T 26-04-2017 A4V04_RS09475 c3cc580583458e9ea76509e6798c6c7a 258 SMART SM00382 36 239 4.3E-12 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS09475 c3cc580583458e9ea76509e6798c6c7a 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 12 258 1.9E-122 T 26-04-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 A4V04_RS09475 c3cc580583458e9ea76509e6798c6c7a 258 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS09475 c3cc580583458e9ea76509e6798c6c7a 258 Pfam PF00005 ABC transporter 28 182 3.8E-31 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS09475 c3cc580583458e9ea76509e6798c6c7a 258 SUPERFAMILY SSF52540 8 247 2.81E-59 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09475 c3cc580583458e9ea76509e6798c6c7a 258 Gene3D G3DSA:3.40.50.300 4 251 1.1E-67 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07550 9cbbaf8ed60f58d45b652b2b330ef5c6 329 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 2.0E-9 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS07550 9cbbaf8ed60f58d45b652b2b330ef5c6 329 Gene3D G3DSA:3.40.190.10 95 180 1.3E-10 T 26-04-2017 A4V04_RS07550 9cbbaf8ed60f58d45b652b2b330ef5c6 329 SUPERFAMILY SSF46785 6 88 3.13E-12 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07550 9cbbaf8ed60f58d45b652b2b330ef5c6 329 Pfam PF03466 LysR substrate binding domain 95 294 4.7E-14 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS07550 9cbbaf8ed60f58d45b652b2b330ef5c6 329 Gene3D G3DSA:3.40.190.10 181 264 4.9E-8 T 26-04-2017 A4V04_RS07550 9cbbaf8ed60f58d45b652b2b330ef5c6 329 Gene3D G3DSA:1.10.10.10 6 83 1.1E-13 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07550 9cbbaf8ed60f58d45b652b2b330ef5c6 329 SUPERFAMILY SSF53850 94 299 1.99E-20 T 26-04-2017 A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 PRINTS PR00149 Fumarate lyase superfamily signature 146 164 4.2E-23 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 PRINTS PR00149 Fumarate lyase superfamily signature 101 119 4.2E-23 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 4.2E-23 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 PRINTS PR00149 Fumarate lyase superfamily signature 231 258 4.2E-23 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 SMART SM00998 364 443 8.9E-27 T 26-04-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 Pfam PF10397 Adenylosuccinate lyase C-terminus 365 442 9.3E-21 T 26-04-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 PRINTS PR00145 Argininosuccinate lyase family signature 141 161 5.8E-13 T 26-04-2017 A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 5.8E-13 T 26-04-2017 A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 PRINTS PR00145 Argininosuccinate lyase family signature 100 122 5.8E-13 T 26-04-2017 A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 PRINTS PR00145 Argininosuccinate lyase family signature 231 255 5.8E-13 T 26-04-2017 A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 Gene3D G3DSA:1.10.40.30 371 443 5.4E-28 T 26-04-2017 A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 Gene3D G3DSA:1.10.275.10 5 103 1.8E-26 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 SUPERFAMILY SSF48557 12 445 2.98E-113 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 Pfam PF00206 Lyase 16 299 3.5E-44 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 Gene3D G3DSA:1.20.200.10 104 370 1.1E-79 T 26-04-2017 A4V04_RS11980 2a81f1d015f4565e392b5d55dc07a873 448 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 16 442 4.0E-107 T 26-04-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS12415 ea8322b1adb93ab1857603f63c517401 157 Hamap MF_01114 Regulatory protein RecX [recX]. 3 156 12.972 T 26-04-2017 IPR003783 Regulatory protein RecX GO:0006282 A4V04_RS12415 ea8322b1adb93ab1857603f63c517401 157 Pfam PF02631 RecX family 44 150 2.1E-27 T 26-04-2017 IPR003783 Regulatory protein RecX GO:0006282 A4V04_RS12415 ea8322b1adb93ab1857603f63c517401 157 Gene3D G3DSA:1.10.10.10 60 104 1.7E-6 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS12415 ea8322b1adb93ab1857603f63c517401 157 Gene3D G3DSA:1.10.10.10 107 155 1.4E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS12415 ea8322b1adb93ab1857603f63c517401 157 Gene3D G3DSA:1.10.10.10 11 59 9.4E-9 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS00935 39800185234a86af9624381a731ba076 320 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 137 157 - T 26-04-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A4V04_RS00935 39800185234a86af9624381a731ba076 320 Gene3D G3DSA:3.50.50.60 121 234 8.2E-31 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS00935 39800185234a86af9624381a731ba076 320 Gene3D G3DSA:3.50.50.60 7 120 8.7E-34 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS00935 39800185234a86af9624381a731ba076 320 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 302 6.9E-45 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS00935 39800185234a86af9624381a731ba076 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 8.6E-40 T 26-04-2017 A4V04_RS00935 39800185234a86af9624381a731ba076 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 8.6E-40 T 26-04-2017 A4V04_RS00935 39800185234a86af9624381a731ba076 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 8.6E-40 T 26-04-2017 A4V04_RS00935 39800185234a86af9624381a731ba076 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 8.6E-40 T 26-04-2017 A4V04_RS00935 39800185234a86af9624381a731ba076 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 8.6E-40 T 26-04-2017 A4V04_RS00935 39800185234a86af9624381a731ba076 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 2.7E-74 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS00935 39800185234a86af9624381a731ba076 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 2.7E-74 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS00935 39800185234a86af9624381a731ba076 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 2.7E-74 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS00935 39800185234a86af9624381a731ba076 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 239 260 2.7E-74 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS00935 39800185234a86af9624381a731ba076 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 2.7E-74 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS00935 39800185234a86af9624381a731ba076 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 42 57 2.7E-74 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS00935 39800185234a86af9624381a731ba076 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 63 73 2.7E-74 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS00935 39800185234a86af9624381a731ba076 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 200 216 2.7E-74 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS00935 39800185234a86af9624381a731ba076 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 2.7E-74 T 26-04-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4V04_RS00935 39800185234a86af9624381a731ba076 320 Gene3D G3DSA:3.50.50.60 235 315 1.0E-11 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS00935 39800185234a86af9624381a731ba076 320 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 9 314 9.8E-118 T 26-04-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 A4V04_RS00935 39800185234a86af9624381a731ba076 320 SUPERFAMILY SSF51905 5 314 5.27E-54 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS00035 acfb3cf4e66a4346dfbd4c9039e70ea0 286 Pfam PF00293 NUDIX domain 137 250 2.9E-13 T 26-04-2017 IPR000086 NUDIX hydrolase domain GO:0016787 A4V04_RS00035 acfb3cf4e66a4346dfbd4c9039e70ea0 286 ProSitePatterns PS00893 Nudix box signature. 166 187 - T 26-04-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4V04_RS00035 acfb3cf4e66a4346dfbd4c9039e70ea0 286 Gene3D G3DSA:3.90.79.10 95 265 5.5E-38 T 26-04-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4V04_RS00035 acfb3cf4e66a4346dfbd4c9039e70ea0 286 SUPERFAMILY SSF55811 117 254 2.57E-23 T 26-04-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4V04_RS08615 d7361a93cdf6eb4c6ddc2c7f09c1b7ae 331 SUPERFAMILY SSF51395 18 308 1.26E-81 T 26-04-2017 A4V04_RS08615 d7361a93cdf6eb4c6ddc2c7f09c1b7ae 331 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 8 313 2.8E-105 T 26-04-2017 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 A4V04_RS08615 d7361a93cdf6eb4c6ddc2c7f09c1b7ae 331 Pfam PF01207 Dihydrouridine synthase (Dus) 18 298 1.1E-91 T 26-04-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4V04_RS08615 d7361a93cdf6eb4c6ddc2c7f09c1b7ae 331 Gene3D G3DSA:3.20.20.70 14 248 4.1E-82 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS08615 d7361a93cdf6eb4c6ddc2c7f09c1b7ae 331 Gene3D G3DSA:1.10.1200.80 258 299 1.8E-8 T 26-04-2017 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 A4V04_RS08615 d7361a93cdf6eb4c6ddc2c7f09c1b7ae 331 PIRSF PIRSF006621 5 329 5.0E-95 T 26-04-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4V04_RS08615 d7361a93cdf6eb4c6ddc2c7f09c1b7ae 331 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 99 117 - T 26-04-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4V04_RS06665 d4b24db47a936e5faddd3485d7ddfc96 268 Gene3D G3DSA:3.40.50.300 1 234 9.7E-62 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06665 d4b24db47a936e5faddd3485d7ddfc96 268 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS06665 d4b24db47a936e5faddd3485d7ddfc96 268 SUPERFAMILY SSF52540 1 231 8.34E-55 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06665 d4b24db47a936e5faddd3485d7ddfc96 268 SMART SM00382 31 235 2.5E-11 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS06665 d4b24db47a936e5faddd3485d7ddfc96 268 Pfam PF00005 ABC transporter 22 177 4.7E-28 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS06145 92bb65d1f8b5c84ad4bf94f2127904b1 368 Pfam PF01757 Acyltransferase family 13 333 2.3E-17 T 26-04-2017 IPR002656 Acyltransferase 3 GO:0016747 A4V04_RS11320 c4323163f42ed0a9d69713135f41a9d9 149 SUPERFAMILY SSF52080 4 142 3.4E-43 T 26-04-2017 IPR021131 Ribosomal protein L18e/L15P A4V04_RS11320 c4323163f42ed0a9d69713135f41a9d9 149 Gene3D G3DSA:3.100.10.10 32 145 7.2E-26 T 26-04-2017 A4V04_RS11320 c4323163f42ed0a9d69713135f41a9d9 149 ProSitePatterns PS00475 Ribosomal protein L15 signature. 109 139 - T 26-04-2017 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11320 c4323163f42ed0a9d69713135f41a9d9 149 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 142 1.4E-46 T 26-04-2017 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11320 c4323163f42ed0a9d69713135f41a9d9 149 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 145 19.63 T 26-04-2017 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 A4V04_RS11320 c4323163f42ed0a9d69713135f41a9d9 149 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 143 1.7E-29 T 26-04-2017 IPR021131 Ribosomal protein L18e/L15P A4V04_RS00800 f0fe06a3d6818ab1e2fc182e4c814bab 104 Gene3D G3DSA:3.30.1390.10 10 103 5.3E-35 T 26-04-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4V04_RS00800 f0fe06a3d6818ab1e2fc182e4c814bab 104 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 8 98 23.593 T 26-04-2017 IPR022935 ATP-dependent Clp protease adaptor protein ClpS A4V04_RS00800 f0fe06a3d6818ab1e2fc182e4c814bab 104 SUPERFAMILY SSF54736 19 102 3.09E-26 T 26-04-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4V04_RS00800 f0fe06a3d6818ab1e2fc182e4c814bab 104 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 20 99 1.6E-30 T 26-04-2017 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 A4V04_RS09995 bd7708970b42924515250f8352335bee 842 Pfam PF01131 DNA topoisomerase 153 595 2.7E-117 T 26-04-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A4V04_RS09995 bd7708970b42924515250f8352335bee 842 SMART SM00493 3 126 1.0E-15 T 26-04-2017 IPR006171 Toprim domain A4V04_RS09995 bd7708970b42924515250f8352335bee 842 Gene3D G3DSA:3.40.50.140 3 151 1.5E-45 T 26-04-2017 IPR006171 Toprim domain A4V04_RS09995 bd7708970b42924515250f8352335bee 842 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 1.6E-27 T 26-04-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4V04_RS09995 bd7708970b42924515250f8352335bee 842 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 191 209 1.6E-27 T 26-04-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4V04_RS09995 bd7708970b42924515250f8352335bee 842 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 403 419 1.6E-27 T 26-04-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4V04_RS09995 bd7708970b42924515250f8352335bee 842 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 321 330 1.6E-27 T 26-04-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4V04_RS09995 bd7708970b42924515250f8352335bee 842 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 519 533 1.6E-27 T 26-04-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4V04_RS09995 bd7708970b42924515250f8352335bee 842 Gene3D G3DSA:1.10.290.10 289 416 4.5E-40 T 26-04-2017 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A4V04_RS09995 bd7708970b42924515250f8352335bee 842 SMART SM00436 126 221 1.4E-22 T 26-04-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A4V04_RS09995 bd7708970b42924515250f8352335bee 842 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 315 330 - T 26-04-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 A4V04_RS09995 bd7708970b42924515250f8352335bee 842 Pfam PF01751 Toprim domain 4 129 3.4E-13 T 26-04-2017 IPR006171 Toprim domain A4V04_RS09995 bd7708970b42924515250f8352335bee 842 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 644 8.8E-176 T 26-04-2017 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 A4V04_RS09995 bd7708970b42924515250f8352335bee 842 SMART SM00437 278 556 2.8E-66 T 26-04-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A4V04_RS09995 bd7708970b42924515250f8352335bee 842 Gene3D G3DSA:1.10.460.10 489 609 1.3E-50 T 26-04-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A4V04_RS09995 bd7708970b42924515250f8352335bee 842 Gene3D G3DSA:1.10.460.10 156 215 1.3E-50 T 26-04-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A4V04_RS09995 bd7708970b42924515250f8352335bee 842 Pfam PF13342 C-terminal repeat of topoisomerase 647 706 4.9E-17 T 26-04-2017 IPR025589 Topoisomerase C-terminal repeat A4V04_RS09995 bd7708970b42924515250f8352335bee 842 Pfam PF13342 C-terminal repeat of topoisomerase 756 816 1.5E-17 T 26-04-2017 IPR025589 Topoisomerase C-terminal repeat A4V04_RS09995 bd7708970b42924515250f8352335bee 842 SUPERFAMILY SSF56712 3 609 2.22E-172 T 26-04-2017 IPR023405 DNA topoisomerase, type IA, core domain A4V04_RS03970 d1f874a3b394f301742aa8928ff14d64 148 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 9 96 7.6E-21 T 26-04-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A4V04_RS03970 d1f874a3b394f301742aa8928ff14d64 148 SUPERFAMILY SSF53146 2 115 9.81E-29 T 26-04-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A4V04_RS03970 d1f874a3b394f301742aa8928ff14d64 148 Gene3D G3DSA:3.30.420.130 3 99 7.9E-30 T 26-04-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A4V04_RS11280 9b8eb6afca8587b826b197ece9ccb1dc 106 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 26-04-2017 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11280 9b8eb6afca8587b826b197ece9ccb1dc 106 SMART SM00739 3 30 2.6E-5 T 26-04-2017 IPR005824 KOW A4V04_RS11280 9b8eb6afca8587b826b197ece9ccb1dc 106 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 102 7.5E-35 T 26-04-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11280 9b8eb6afca8587b826b197ece9ccb1dc 106 SUPERFAMILY SSF50104 3 99 2.83E-32 T 26-04-2017 IPR008991 Translation protein SH3-like domain A4V04_RS11280 9b8eb6afca8587b826b197ece9ccb1dc 106 Gene3D G3DSA:2.30.30.30 3 91 7.0E-23 T 26-04-2017 IPR014722 Ribosomal protein L2 domain 2 A4V04_RS11280 9b8eb6afca8587b826b197ece9ccb1dc 106 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 100 1.4E-25 T 26-04-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11280 9b8eb6afca8587b826b197ece9ccb1dc 106 Pfam PF00467 KOW motif 6 36 6.7E-6 T 26-04-2017 IPR005824 KOW A4V04_RS11280 9b8eb6afca8587b826b197ece9ccb1dc 106 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 96 19.413 T 26-04-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS09740 41cfe9ecc67f56bb81e5ad901bdf2023 269 SUPERFAMILY SSF53474 58 267 7.6E-23 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS09740 41cfe9ecc67f56bb81e5ad901bdf2023 269 Pfam PF12146 Serine aminopeptidase, S33 59 165 1.9E-7 T 26-04-2017 IPR022742 Serine aminopeptidase, S33 A4V04_RS09740 41cfe9ecc67f56bb81e5ad901bdf2023 269 Gene3D G3DSA:3.40.50.1820 39 266 2.1E-21 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS03695 b94fd635474fe609f91a87d801ab7882 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 197 2.5E-15 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS03695 b94fd635474fe609f91a87d801ab7882 206 SUPERFAMILY SSF46894 134 200 2.48E-15 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS03695 b94fd635474fe609f91a87d801ab7882 206 Gene3D G3DSA:1.10.10.10 147 199 1.9E-16 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS03695 b94fd635474fe609f91a87d801ab7882 206 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS03695 b94fd635474fe609f91a87d801ab7882 206 SUPERFAMILY SSF52172 11 155 8.11E-34 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS03695 b94fd635474fe609f91a87d801ab7882 206 SMART SM00448 8 119 2.1E-25 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS03695 b94fd635474fe609f91a87d801ab7882 206 Gene3D G3DSA:3.40.50.2300 10 146 4.0E-31 T 26-04-2017 A4V04_RS03695 b94fd635474fe609f91a87d801ab7882 206 SMART SM00421 143 200 2.1E-14 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS03695 b94fd635474fe609f91a87d801ab7882 206 Pfam PF00072 Response regulator receiver domain 10 119 3.9E-27 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS03695 b94fd635474fe609f91a87d801ab7882 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 3.4E-12 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS03695 b94fd635474fe609f91a87d801ab7882 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 3.4E-12 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS03695 b94fd635474fe609f91a87d801ab7882 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 3.4E-12 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS04240 b56477fc17893c05d3a46e6cba699dec 661 SUPERFAMILY SSF51905 145 274 7.41E-56 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04240 b56477fc17893c05d3a46e6cba699dec 661 SUPERFAMILY SSF51905 374 447 7.41E-56 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04240 b56477fc17893c05d3a46e6cba699dec 661 SUPERFAMILY SSF51905 3 116 7.41E-56 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04240 b56477fc17893c05d3a46e6cba699dec 661 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 41 50 - T 26-04-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04240 b56477fc17893c05d3a46e6cba699dec 661 Pfam PF02910 Fumarate reductase flavoprotein C-term 470 599 7.5E-34 T 26-04-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04240 b56477fc17893c05d3a46e6cba699dec 661 SUPERFAMILY SSF56425 251 371 4.78E-38 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04240 b56477fc17893c05d3a46e6cba699dec 661 Gene3D G3DSA:4.10.80.40 550 585 5.4E-10 T 26-04-2017 A4V04_RS04240 b56477fc17893c05d3a46e6cba699dec 661 SUPERFAMILY SSF46977 462 651 1.13E-50 T 26-04-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04240 b56477fc17893c05d3a46e6cba699dec 661 Gene3D G3DSA:3.90.700.10 258 365 6.0E-37 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04240 b56477fc17893c05d3a46e6cba699dec 661 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 599 3.9E-211 T 26-04-2017 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04240 b56477fc17893c05d3a46e6cba699dec 661 Gene3D G3DSA:3.50.50.60 4 257 2.6E-86 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04240 b56477fc17893c05d3a46e6cba699dec 661 Gene3D G3DSA:3.50.50.60 366 431 2.6E-86 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04240 b56477fc17893c05d3a46e6cba699dec 661 Pfam PF00890 FAD binding domain 7 411 2.3E-116 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04240 b56477fc17893c05d3a46e6cba699dec 661 Gene3D G3DSA:1.20.58.100 444 549 7.6E-33 T 26-04-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02545 d48c1574cdc359609cd950a72cca9489 157 SUPERFAMILY SSF55031 2 59 1.92E-6 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS02545 d48c1574cdc359609cd950a72cca9489 157 Gene3D G3DSA:3.30.70.360 1 58 3.9E-8 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS02545 d48c1574cdc359609cd950a72cca9489 157 Gene3D G3DSA:3.40.630.10 59 153 6.4E-7 T 26-04-2017 A4V04_RS07820 e2d6659ebfcf947a14b342fb4eb20bfe 217 Gene3D G3DSA:1.10.10.10 155 214 1.9E-25 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07820 e2d6659ebfcf947a14b342fb4eb20bfe 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS07820 e2d6659ebfcf947a14b342fb4eb20bfe 217 SUPERFAMILY SSF52172 8 137 5.83E-33 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS07820 e2d6659ebfcf947a14b342fb4eb20bfe 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 4.3E-12 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS07820 e2d6659ebfcf947a14b342fb4eb20bfe 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 4.3E-12 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS07820 e2d6659ebfcf947a14b342fb4eb20bfe 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 4.3E-12 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS07820 e2d6659ebfcf947a14b342fb4eb20bfe 217 Pfam PF00072 Response regulator receiver domain 9 120 3.5E-29 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS07820 e2d6659ebfcf947a14b342fb4eb20bfe 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 6.6E-20 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS07820 e2d6659ebfcf947a14b342fb4eb20bfe 217 SMART SM00421 153 210 4.9E-21 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS07820 e2d6659ebfcf947a14b342fb4eb20bfe 217 SMART SM00448 7 120 8.1E-31 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS07820 e2d6659ebfcf947a14b342fb4eb20bfe 217 SUPERFAMILY SSF46894 148 214 4.08E-19 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS07820 e2d6659ebfcf947a14b342fb4eb20bfe 217 Gene3D G3DSA:3.40.50.2300 7 154 9.1E-37 T 26-04-2017 A4V04_RS00880 9f5055d811e7bb8ae9d6a8db993579c8 639 TIGRFAM TIGR01391 dnaG: DNA primase 1 407 2.2E-133 T 26-04-2017 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 A4V04_RS00880 9f5055d811e7bb8ae9d6a8db993579c8 639 Gene3D G3DSA:3.40.1360.10 231 357 1.2E-42 T 26-04-2017 A4V04_RS00880 9f5055d811e7bb8ae9d6a8db993579c8 639 Gene3D G3DSA:3.90.980.10 109 230 1.5E-39 T 26-04-2017 IPR013264 DNA primase, catalytic core, N-terminal A4V04_RS00880 9f5055d811e7bb8ae9d6a8db993579c8 639 Gene3D G3DSA:3.90.580.10 1 96 8.3E-37 T 26-04-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A4V04_RS00880 9f5055d811e7bb8ae9d6a8db993579c8 639 SMART SM00400 34 86 1.4E-32 T 26-04-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A4V04_RS00880 9f5055d811e7bb8ae9d6a8db993579c8 639 Gene3D G3DSA:1.20.50.20 358 413 1.8E-9 T 26-04-2017 A4V04_RS00880 9f5055d811e7bb8ae9d6a8db993579c8 639 Pfam PF08275 DNA primase catalytic core, N-terminal domain 119 241 9.5E-38 T 26-04-2017 IPR013264 DNA primase, catalytic core, N-terminal A4V04_RS00880 9f5055d811e7bb8ae9d6a8db993579c8 639 SUPERFAMILY SSF57783 2 94 1.33E-32 T 26-04-2017 A4V04_RS00880 9f5055d811e7bb8ae9d6a8db993579c8 639 Pfam PF10410 DnaB-helicase binding domain of primase 359 413 3.5E-11 T 26-04-2017 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 A4V04_RS00880 9f5055d811e7bb8ae9d6a8db993579c8 639 SMART SM00493 249 320 3.6E-12 T 26-04-2017 IPR006171 Toprim domain A4V04_RS00880 9f5055d811e7bb8ae9d6a8db993579c8 639 Hamap MF_00974 DNA primase [dnaG]. 1 617 26.389 T 26-04-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A4V04_RS00880 9f5055d811e7bb8ae9d6a8db993579c8 639 SUPERFAMILY SSF56731 109 413 4.97E-98 T 26-04-2017 A4V04_RS00880 9f5055d811e7bb8ae9d6a8db993579c8 639 Pfam PF13662 Toprim domain 250 324 4.3E-15 T 26-04-2017 IPR006171 Toprim domain A4V04_RS00880 9f5055d811e7bb8ae9d6a8db993579c8 639 Pfam PF01807 CHC2 zinc finger 2 96 1.2E-35 T 26-04-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A4V04_RS12080 76a3712a7072f145f0c2ce560dc080d2 696 Pfam PF11412 Disulphide bond corrector protein DsbC 47 157 1.2E-19 T 26-04-2017 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain A4V04_RS12080 76a3712a7072f145f0c2ce560dc080d2 696 Pfam PF13899 Thioredoxin-like 587 671 2.1E-17 T 26-04-2017 A4V04_RS12080 76a3712a7072f145f0c2ce560dc080d2 696 SUPERFAMILY SSF52833 592 692 2.27E-16 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS12080 76a3712a7072f145f0c2ce560dc080d2 696 Gene3D G3DSA:3.40.30.10 587 687 6.7E-18 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS12080 76a3712a7072f145f0c2ce560dc080d2 696 ProSitePatterns PS00194 Thioredoxin family active site. 604 622 - T 26-04-2017 IPR017937 Thioredoxin, conserved site GO:0045454 A4V04_RS12080 76a3712a7072f145f0c2ce560dc080d2 696 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 306 506 1.2E-7 T 26-04-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 A4V04_RS08175 6ea12400da058701f6979415b9d452a1 273 Gene3D G3DSA:3.60.110.10 1 269 1.7E-74 T 26-04-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4V04_RS08175 6ea12400da058701f6979415b9d452a1 273 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 155 175 - T 26-04-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site A4V04_RS08175 6ea12400da058701f6979415b9d452a1 273 SUPERFAMILY SSF56317 2 269 7.98E-72 T 26-04-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4V04_RS08175 6ea12400da058701f6979415b9d452a1 273 Pfam PF00795 Carbon-nitrogen hydrolase 3 260 4.9E-49 T 26-04-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 41 180 5.6E-16 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 Pfam PF01751 Toprim domain 429 541 2.6E-12 T 26-04-2017 IPR006171 Toprim domain A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 SUPERFAMILY SSF54211 229 398 3.6E-34 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 585 649 6.6E-20 T 26-04-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 SMART SM00387 34 169 1.0E-15 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR00418 DNA topoisomerase II family signature 73 86 6.3E-60 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR00418 DNA topoisomerase II family signature 38 53 6.3E-60 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR00418 DNA topoisomerase II family signature 119 133 6.3E-60 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR00418 DNA topoisomerase II family signature 282 295 6.3E-60 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR00418 DNA topoisomerase II family signature 499 515 6.3E-60 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR00418 DNA topoisomerase II family signature 517 534 6.3E-60 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR00418 DNA topoisomerase II family signature 430 444 6.3E-60 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR00418 DNA topoisomerase II family signature 537 549 6.3E-60 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR00418 DNA topoisomerase II family signature 589 605 6.3E-60 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 Gene3D G3DSA:3.40.50.670 414 616 7.8E-69 T 26-04-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 Gene3D G3DSA:3.30.565.10 22 226 1.1E-66 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 SMART SM00433 40 653 2.5E-176 T 26-04-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 ProSitePatterns PS00177 DNA topoisomerase II signature. 432 440 - T 26-04-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR01098 Topoisomerase IV subunit B signature 185 202 3.6E-32 T 26-04-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR01098 Topoisomerase IV subunit B signature 203 224 3.6E-32 T 26-04-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR01098 Topoisomerase IV subunit B signature 327 342 3.6E-32 T 26-04-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR01098 Topoisomerase IV subunit B signature 464 485 3.6E-32 T 26-04-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR01098 Topoisomerase IV subunit B signature 310 326 3.6E-32 T 26-04-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR01098 Topoisomerase IV subunit B signature 378 403 3.6E-32 T 26-04-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR01098 Topoisomerase IV subunit B signature 145 159 3.6E-32 T 26-04-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR01098 Topoisomerase IV subunit B signature 354 377 3.6E-32 T 26-04-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 PRINTS PR01098 Topoisomerase IV subunit B signature 33 46 3.6E-32 T 26-04-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 SUPERFAMILY SSF55874 12 226 8.77E-57 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 Pfam PF00204 DNA gyrase B 251 398 1.2E-33 T 26-04-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 SUPERFAMILY SSF56719 405 652 1.7E-70 T 26-04-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 Gene3D G3DSA:3.30.230.10 229 398 1.4E-36 T 26-04-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4V04_RS03075 245515bd69a087bb0ae90ec62622d5c7 659 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 9 657 42.134 T 26-04-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4V04_RS12390 55cb915c5d02f949680ce2b48b9cbde5 320 SUPERFAMILY SSF46785 5 83 6.8E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS12390 55cb915c5d02f949680ce2b48b9cbde5 320 Gene3D G3DSA:3.40.190.10 178 261 6.2E-9 T 26-04-2017 A4V04_RS12390 55cb915c5d02f949680ce2b48b9cbde5 320 Gene3D G3DSA:3.40.190.10 106 177 9.3E-6 T 26-04-2017 A4V04_RS12390 55cb915c5d02f949680ce2b48b9cbde5 320 Gene3D G3DSA:1.10.10.10 2 81 2.4E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS12390 55cb915c5d02f949680ce2b48b9cbde5 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 3.9E-16 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS12390 55cb915c5d02f949680ce2b48b9cbde5 320 Pfam PF03466 LysR substrate binding domain 94 276 1.6E-15 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS12390 55cb915c5d02f949680ce2b48b9cbde5 320 SUPERFAMILY SSF53850 106 290 1.39E-16 T 26-04-2017 A4V04_RS06595 454e134ef003e0101976540c711f572d 200 Gene3D G3DSA:3.40.50.300 7 140 3.1E-6 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06595 454e134ef003e0101976540c711f572d 200 SUPERFAMILY SSF52540 4 138 1.25E-6 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06900 41d59018099d1e6c23f5e02737ff9b7b 377 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 3 366 56.579 T 26-04-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A4V04_RS06900 41d59018099d1e6c23f5e02737ff9b7b 377 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 5 371 7.2E-167 T 26-04-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A4V04_RS06900 41d59018099d1e6c23f5e02737ff9b7b 377 SUPERFAMILY SSF51713 2 370 1.44E-160 T 26-04-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A4V04_RS06900 41d59018099d1e6c23f5e02737ff9b7b 377 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 5 371 1.1E-158 T 26-04-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A4V04_RS06900 41d59018099d1e6c23f5e02737ff9b7b 377 Pfam PF01702 Queuine tRNA-ribosyltransferase 129 368 2.0E-93 T 26-04-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A4V04_RS06900 41d59018099d1e6c23f5e02737ff9b7b 377 Gene3D G3DSA:3.20.20.105 2 372 5.8E-168 T 26-04-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A4V04_RS06705 4217012a68848342d1500975dfb2fb37 262 SUPERFAMILY SSF56300 23 238 3.3E-22 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS06705 4217012a68848342d1500975dfb2fb37 262 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 262 73.297 T 26-04-2017 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 A4V04_RS06705 4217012a68848342d1500975dfb2fb37 262 Gene3D G3DSA:3.60.21.10 191 239 1.7E-15 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS06705 4217012a68848342d1500975dfb2fb37 262 Gene3D G3DSA:3.60.21.10 23 143 1.7E-15 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS06705 4217012a68848342d1500975dfb2fb37 262 Pfam PF00149 Calcineurin-like phosphoesterase 23 217 1.1E-7 T 26-04-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4V04_RS06705 4217012a68848342d1500975dfb2fb37 262 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 23 240 1.8E-61 T 26-04-2017 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 A4V04_RS09915 8485cb68dc1b0c7e11b03d06af7d7acb 463 SUPERFAMILY SSF103473 8 459 2.35E-29 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS09915 8485cb68dc1b0c7e11b03d06af7d7acb 463 Gene3D G3DSA:1.20.1250.20 274 458 3.9E-10 T 26-04-2017 A4V04_RS09915 8485cb68dc1b0c7e11b03d06af7d7acb 463 Gene3D G3DSA:1.20.1250.20 19 228 5.9E-12 T 26-04-2017 A4V04_RS09915 8485cb68dc1b0c7e11b03d06af7d7acb 463 Pfam PF07690 Major Facilitator Superfamily 40 322 1.7E-10 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS03350 11e3d881e146af9f51c96d2a07dd8c62 527 Pfam PF03553 Na+/H+ antiporter family 171 480 4.6E-60 T 26-04-2017 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A4V04_RS09280 1f29c98161fe3722552b37c047e141c8 774 Gene3D G3DSA:3.40.228.10 161 361 1.1E-51 T 26-04-2017 A4V04_RS09280 1f29c98161fe3722552b37c047e141c8 774 SUPERFAMILY SSF50692 599 762 9.32E-21 T 26-04-2017 IPR009010 Aspartate decarboxylase-like domain A4V04_RS09280 1f29c98161fe3722552b37c047e141c8 774 Gene3D G3DSA:3.40.50.740 362 611 2.3E-68 T 26-04-2017 A4V04_RS09280 1f29c98161fe3722552b37c047e141c8 774 Gene3D G3DSA:3.40.50.740 64 156 2.3E-68 T 26-04-2017 A4V04_RS09280 1f29c98161fe3722552b37c047e141c8 774 Gene3D G3DSA:2.40.40.20 619 762 1.3E-26 T 26-04-2017 A4V04_RS09280 1f29c98161fe3722552b37c047e141c8 774 Pfam PF01568 Molydopterin dinucleotide binding domain 641 749 2.6E-12 T 26-04-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4V04_RS09280 1f29c98161fe3722552b37c047e141c8 774 SUPERFAMILY SSF53706 23 635 4.06E-155 T 26-04-2017 A4V04_RS09280 1f29c98161fe3722552b37c047e141c8 774 Pfam PF00384 Molybdopterin oxidoreductase 64 527 1.0E-75 T 26-04-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS09280 1f29c98161fe3722552b37c047e141c8 774 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 469 486 - T 26-04-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A4V04_RS01595 e20aa1d090cd6099898afd51497358d7 484 ProSitePatterns PS00163 Fumarate lyases signature. 322 331 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS01595 e20aa1d090cd6099898afd51497358d7 484 PRINTS PR00149 Fumarate lyase superfamily signature 276 303 6.5E-21 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01595 e20aa1d090cd6099898afd51497358d7 484 PRINTS PR00149 Fumarate lyase superfamily signature 131 149 6.5E-21 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01595 e20aa1d090cd6099898afd51497358d7 484 PRINTS PR00149 Fumarate lyase superfamily signature 322 338 6.5E-21 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01595 e20aa1d090cd6099898afd51497358d7 484 PRINTS PR00149 Fumarate lyase superfamily signature 176 194 6.5E-21 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01595 e20aa1d090cd6099898afd51497358d7 484 Gene3D G3DSA:1.10.40.30 413 468 3.3E-9 T 26-04-2017 A4V04_RS01595 e20aa1d090cd6099898afd51497358d7 484 SUPERFAMILY SSF48557 1 463 3.09E-105 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS01595 e20aa1d090cd6099898afd51497358d7 484 Gene3D G3DSA:1.20.200.10 136 408 4.2E-70 T 26-04-2017 A4V04_RS01595 e20aa1d090cd6099898afd51497358d7 484 Gene3D G3DSA:1.10.275.10 1 135 9.0E-51 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS01595 e20aa1d090cd6099898afd51497358d7 484 Pfam PF10415 Fumarase C C-terminus 413 465 3.5E-9 T 26-04-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS01595 e20aa1d090cd6099898afd51497358d7 484 Pfam PF00206 Lyase 11 346 1.7E-73 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS04020 395fc0c274c46262f3fddf37f762aef9 267 Pfam PF01614 Bacterial transcriptional regulator 131 249 4.0E-25 T 26-04-2017 IPR014757 Transcription regulator IclR, C-terminal A4V04_RS04020 395fc0c274c46262f3fddf37f762aef9 267 SUPERFAMILY SSF55781 68 253 5.43E-40 T 26-04-2017 IPR029016 GAF domain-like A4V04_RS04020 395fc0c274c46262f3fddf37f762aef9 267 SUPERFAMILY SSF46785 10 84 4.12E-15 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04020 395fc0c274c46262f3fddf37f762aef9 267 Pfam PF09339 IclR helix-turn-helix domain 13 61 1.9E-9 T 26-04-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4V04_RS04020 395fc0c274c46262f3fddf37f762aef9 267 Gene3D G3DSA:1.10.10.10 9 81 1.2E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04020 395fc0c274c46262f3fddf37f762aef9 267 SMART SM00346 10 100 8.8E-15 T 26-04-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4V04_RS04020 395fc0c274c46262f3fddf37f762aef9 267 Gene3D G3DSA:3.30.450.40 82 254 2.6E-44 T 26-04-2017 IPR029016 GAF domain-like A4V04_RS05385 da8e292d7260dcc00d5920c60ec285cf 476 Pfam PF00890 FAD binding domain 34 457 1.2E-62 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS05385 da8e292d7260dcc00d5920c60ec285cf 476 Gene3D G3DSA:3.90.700.10 294 403 2.7E-18 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS05385 da8e292d7260dcc00d5920c60ec285cf 476 Gene3D G3DSA:3.50.50.60 413 473 1.8E-87 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS05385 da8e292d7260dcc00d5920c60ec285cf 476 Gene3D G3DSA:3.50.50.60 30 273 1.8E-87 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS05385 da8e292d7260dcc00d5920c60ec285cf 476 SUPERFAMILY SSF51905 33 300 1.3E-52 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS05385 da8e292d7260dcc00d5920c60ec285cf 476 SUPERFAMILY SSF51905 416 473 1.3E-52 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS05385 da8e292d7260dcc00d5920c60ec285cf 476 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 34 469 7.7E-101 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS05385 da8e292d7260dcc00d5920c60ec285cf 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 192 217 4.5E-6 T 26-04-2017 A4V04_RS05385 da8e292d7260dcc00d5920c60ec285cf 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 34 56 4.5E-6 T 26-04-2017 A4V04_RS05385 da8e292d7260dcc00d5920c60ec285cf 476 SUPERFAMILY SSF56425 292 417 2.41E-19 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11420 02e197c67c7f260422dbb517c2a44e9b 228 SUPERFAMILY SSF89155 26 47 1.83E-36 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS11420 02e197c67c7f260422dbb517c2a44e9b 228 SUPERFAMILY SSF89155 80 218 1.83E-36 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS11420 02e197c67c7f260422dbb517c2a44e9b 228 Gene3D G3DSA:1.10.3480.10 77 219 2.1E-41 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS11420 02e197c67c7f260422dbb517c2a44e9b 228 Gene3D G3DSA:1.10.3480.10 26 43 2.1E-41 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS11420 02e197c67c7f260422dbb517c2a44e9b 228 Pfam PF02613 Nitrate reductase delta subunit 64 188 6.8E-33 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS02500 599e26263eb8efafe84ffcf7caaa1d10 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 62 412 3.7E-109 T 26-04-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4V04_RS02500 599e26263eb8efafe84ffcf7caaa1d10 421 Pfam PF00696 Amino acid kinase family 3 229 2.8E-48 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS02500 599e26263eb8efafe84ffcf7caaa1d10 421 Pfam PF13840 ACT domain 347 409 1.0E-16 T 26-04-2017 IPR027795 GATS-like ACT domain A4V04_RS02500 599e26263eb8efafe84ffcf7caaa1d10 421 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 412 9.5E-129 T 26-04-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4V04_RS02500 599e26263eb8efafe84ffcf7caaa1d10 421 SUPERFAMILY SSF53633 4 250 7.72E-72 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS02500 599e26263eb8efafe84ffcf7caaa1d10 421 PIRSF PIRSF000726 59 420 1.2E-131 T 26-04-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4V04_RS02500 599e26263eb8efafe84ffcf7caaa1d10 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 26-04-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4V04_RS02500 599e26263eb8efafe84ffcf7caaa1d10 421 SUPERFAMILY SSF55021 342 415 1.68E-24 T 26-04-2017 A4V04_RS02500 599e26263eb8efafe84ffcf7caaa1d10 421 SUPERFAMILY SSF55021 257 335 1.11E-18 T 26-04-2017 A4V04_RS02500 599e26263eb8efafe84ffcf7caaa1d10 421 Gene3D G3DSA:3.40.1160.10 1 254 4.9E-71 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS02500 599e26263eb8efafe84ffcf7caaa1d10 421 Pfam PF01842 ACT domain 277 333 7.0E-7 T 26-04-2017 IPR002912 ACT domain GO:0008152|GO:0016597 A4V04_RS02500 599e26263eb8efafe84ffcf7caaa1d10 421 PRINTS PR00474 Glutamate 5-kinase family signature 152 179 1.2E-5 T 26-04-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4V04_RS02500 599e26263eb8efafe84ffcf7caaa1d10 421 PRINTS PR00474 Glutamate 5-kinase family signature 33 47 1.2E-5 T 26-04-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4V04_RS10960 62d55ae140d4d78f3247c90b5dcd9527 408 PIRSF PIRSF005962 6 391 2.3E-92 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS10960 62d55ae140d4d78f3247c90b5dcd9527 408 Gene3D G3DSA:3.40.630.10 99 229 4.0E-58 T 26-04-2017 A4V04_RS10960 62d55ae140d4d78f3247c90b5dcd9527 408 Gene3D G3DSA:3.40.630.10 10 61 4.0E-58 T 26-04-2017 A4V04_RS10960 62d55ae140d4d78f3247c90b5dcd9527 408 Gene3D G3DSA:3.40.630.10 343 383 4.0E-58 T 26-04-2017 A4V04_RS10960 62d55ae140d4d78f3247c90b5dcd9527 408 SUPERFAMILY SSF53187 99 247 4.49E-51 T 26-04-2017 A4V04_RS10960 62d55ae140d4d78f3247c90b5dcd9527 408 SUPERFAMILY SSF53187 16 61 4.49E-51 T 26-04-2017 A4V04_RS10960 62d55ae140d4d78f3247c90b5dcd9527 408 SUPERFAMILY SSF53187 346 384 4.49E-51 T 26-04-2017 A4V04_RS10960 62d55ae140d4d78f3247c90b5dcd9527 408 Gene3D G3DSA:3.30.70.360 234 339 6.9E-24 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS10960 62d55ae140d4d78f3247c90b5dcd9527 408 Pfam PF01546 Peptidase family M20/M25/M40 117 383 6.8E-20 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS10960 62d55ae140d4d78f3247c90b5dcd9527 408 SUPERFAMILY SSF55031 232 340 2.36E-21 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS10960 62d55ae140d4d78f3247c90b5dcd9527 408 Pfam PF07687 Peptidase dimerisation domain 237 331 5.9E-9 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS10960 62d55ae140d4d78f3247c90b5dcd9527 408 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 23 384 9.1E-78 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS05435 5036daf67ea4727034f599dfab637129 286 Pfam PF12710 haloacid dehalogenase-like hydrolase 78 250 1.0E-20 T 26-04-2017 A4V04_RS05435 5036daf67ea4727034f599dfab637129 286 Gene3D G3DSA:1.10.150.210 88 135 3.4E-17 T 26-04-2017 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 A4V04_RS05435 5036daf67ea4727034f599dfab637129 286 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 67 283 7.6E-54 T 26-04-2017 A4V04_RS05435 5036daf67ea4727034f599dfab637129 286 SUPERFAMILY SSF56784 70 284 5.02E-44 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS05435 5036daf67ea4727034f599dfab637129 286 Gene3D G3DSA:3.40.50.1000 136 271 8.7E-39 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS05435 5036daf67ea4727034f599dfab637129 286 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 75 252 6.7E-27 T 26-04-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 A4V04_RS10570 f768c95ee47673b9395d66858237ccdc 508 SUPERFAMILY SSF51905 40 298 6.36E-53 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10570 f768c95ee47673b9395d66858237ccdc 508 SUPERFAMILY SSF51905 443 501 6.36E-53 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10570 f768c95ee47673b9395d66858237ccdc 508 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 42 496 1.5E-152 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS10570 f768c95ee47673b9395d66858237ccdc 508 SUPERFAMILY SSF56425 285 442 1.26E-34 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10570 f768c95ee47673b9395d66858237ccdc 508 Gene3D G3DSA:3.50.50.60 32 281 7.9E-85 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10570 f768c95ee47673b9395d66858237ccdc 508 Gene3D G3DSA:3.50.50.60 440 501 7.9E-85 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10570 f768c95ee47673b9395d66858237ccdc 508 Gene3D G3DSA:3.90.700.10 308 435 2.2E-30 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10570 f768c95ee47673b9395d66858237ccdc 508 Pfam PF00890 FAD binding domain 42 484 1.9E-82 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10570 f768c95ee47673b9395d66858237ccdc 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 43 62 2.3E-6 T 26-04-2017 A4V04_RS10570 f768c95ee47673b9395d66858237ccdc 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 449 471 2.3E-6 T 26-04-2017 A4V04_RS06290 63d2fe6a67a0a8131f71be6231829429 280 Pfam PF03524 Conjugal transfer protein 35 252 6.8E-55 T 26-04-2017 IPR010258 Conjugal transfer, TrbG/VirB9/CagX A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 Pfam PF13187 4Fe-4S dicluster domain 149 208 9.5E-7 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 Pfam PF02256 Iron hydrogenase small subunit 529 580 6.3E-22 T 26-04-2017 IPR003149 Iron hydrogenase, small subunit A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 150 161 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 143 519 1.8E-138 T 26-04-2017 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 SUPERFAMILY SSF54862 78 216 1.72E-30 T 26-04-2017 A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 SUPERFAMILY SSF53920 193 578 2.49E-110 T 26-04-2017 IPR009016 Iron hydrogenase A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 Gene3D G3DSA:3.30.70.20 135 201 3.0E-14 T 26-04-2017 A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 Gene3D G3DSA:3.40.50.1780 202 252 3.6E-64 T 26-04-2017 A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 Gene3D G3DSA:3.40.50.1780 305 436 3.6E-64 T 26-04-2017 A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 194 205 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 SMART SM00929 86 126 2.8E-8 T 26-04-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 SMART SM00902 522 581 1.8E-19 T 26-04-2017 IPR003149 Iron hydrogenase, small subunit A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 5 79 5.6E-9 T 26-04-2017 A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 229 515 1.6E-80 T 26-04-2017 IPR004108 Iron hydrogenase, large subunit, C-terminal A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 86 122 6.2E-10 T 26-04-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 SUPERFAMILY SSF54292 4 77 1.06E-9 T 26-04-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4V04_RS04865 1a711f8ab84529e43542c1c9394a74e0 598 Gene3D G3DSA:4.10.260.20 529 585 2.6E-23 T 26-04-2017 IPR003149 Iron hydrogenase, small subunit A4V04_RS02005 45ccce6a5d6d543d702d740358e62634 622 Pfam PF03577 Peptidase family C69 46 331 1.6E-42 T 26-04-2017 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 A4V04_RS03725 661d22ba50ef76a4cbf2ae56139c3e0a 711 Gene3D G3DSA:3.40.50.720 4 133 2.7E-41 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03725 661d22ba50ef76a4cbf2ae56139c3e0a 711 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 157 294 9.6E-46 T 26-04-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A4V04_RS03725 661d22ba50ef76a4cbf2ae56139c3e0a 711 SUPERFAMILY SSF52210 133 300 4.32E-38 T 26-04-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS03725 661d22ba50ef76a4cbf2ae56139c3e0a 711 Pfam PF13549 ATP-grasp domain 480 701 1.3E-75 T 26-04-2017 A4V04_RS03725 661d22ba50ef76a4cbf2ae56139c3e0a 711 SUPERFAMILY SSF51735 2 140 1.43E-37 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03725 661d22ba50ef76a4cbf2ae56139c3e0a 711 SUPERFAMILY SSF52210 300 455 2.35E-32 T 26-04-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS03725 661d22ba50ef76a4cbf2ae56139c3e0a 711 SUPERFAMILY SSF56059 492 701 1.13E-41 T 26-04-2017 A4V04_RS03725 661d22ba50ef76a4cbf2ae56139c3e0a 711 Gene3D G3DSA:3.40.50.261 291 434 1.8E-14 T 26-04-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS03725 661d22ba50ef76a4cbf2ae56139c3e0a 711 SMART SM00881 9 104 1.5E-32 T 26-04-2017 IPR003781 CoA-binding GO:0048037 A4V04_RS03725 661d22ba50ef76a4cbf2ae56139c3e0a 711 Gene3D G3DSA:3.30.470.20 496 599 1.1E-9 T 26-04-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4V04_RS03725 661d22ba50ef76a4cbf2ae56139c3e0a 711 Gene3D G3DSA:3.40.50.261 134 290 1.5E-31 T 26-04-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS03725 661d22ba50ef76a4cbf2ae56139c3e0a 711 Pfam PF13380 CoA binding domain 14 139 2.6E-26 T 26-04-2017 IPR003781 CoA-binding GO:0048037 A4V04_RS06675 4b2c4d02f26e847425de2cf876ef6608 322 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 155 168 3.2E-46 T 26-04-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS06675 4b2c4d02f26e847425de2cf876ef6608 322 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 90 101 3.2E-46 T 26-04-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS06675 4b2c4d02f26e847425de2cf876ef6608 322 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 171 184 3.2E-46 T 26-04-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS06675 4b2c4d02f26e847425de2cf876ef6608 322 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 115 133 3.2E-46 T 26-04-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS06675 4b2c4d02f26e847425de2cf876ef6608 322 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 199 208 3.2E-46 T 26-04-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS06675 4b2c4d02f26e847425de2cf876ef6608 322 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 136 152 3.2E-46 T 26-04-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS06675 4b2c4d02f26e847425de2cf876ef6608 322 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 150 1.2E-63 T 26-04-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS06675 4b2c4d02f26e847425de2cf876ef6608 322 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 6 318 49.346 T 26-04-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS06675 4b2c4d02f26e847425de2cf876ef6608 322 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 4 320 1.5E-145 T 26-04-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS06675 4b2c4d02f26e847425de2cf876ef6608 322 Gene3D G3DSA:3.90.226.10 65 289 3.5E-50 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS06675 4b2c4d02f26e847425de2cf876ef6608 322 SUPERFAMILY SSF52096 6 318 2.42E-100 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS12615 a7f3ad639c3db5d312ad6d9558d7a69c 214 Gene3D G3DSA:3.40.190.10 1 145 6.3E-41 T 26-04-2017 A4V04_RS12615 a7f3ad639c3db5d312ad6d9558d7a69c 214 SUPERFAMILY SSF53850 1 210 4.52E-62 T 26-04-2017 A4V04_RS12615 a7f3ad639c3db5d312ad6d9558d7a69c 214 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 146 167 - T 26-04-2017 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 A4V04_RS12615 a7f3ad639c3db5d312ad6d9558d7a69c 214 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 187 1.9E-55 T 26-04-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A4V04_RS12615 a7f3ad639c3db5d312ad6d9558d7a69c 214 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 1 211 50.436 T 26-04-2017 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 A4V04_RS12615 a7f3ad639c3db5d312ad6d9558d7a69c 214 Pfam PF01634 ATP phosphoribosyltransferase 51 204 3.0E-46 T 26-04-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A4V04_RS11510 19d1d4fe50afb12d22bf0046a4ed84a5 213 Pfam PF01926 50S ribosome-binding GTPase 27 143 5.2E-14 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS11510 19d1d4fe50afb12d22bf0046a4ed84a5 213 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 8 203 2.8E-55 T 26-04-2017 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A4V04_RS11510 19d1d4fe50afb12d22bf0046a4ed84a5 213 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 13 207 23.151 T 26-04-2017 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A4V04_RS11510 19d1d4fe50afb12d22bf0046a4ed84a5 213 Gene3D G3DSA:3.40.50.300 8 205 2.1E-31 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11510 19d1d4fe50afb12d22bf0046a4ed84a5 213 SUPERFAMILY SSF52540 8 207 7.71E-30 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00300 ab7a0bf6fe5a9bd1889cafe42d58d046 498 SUPERFAMILY SSF117892 225 350 3.14E-20 T 26-04-2017 IPR001107 Band 7 domain A4V04_RS00300 ab7a0bf6fe5a9bd1889cafe42d58d046 498 SMART SM00244 169 343 1.2E-26 T 26-04-2017 IPR001107 Band 7 domain A4V04_RS00300 ab7a0bf6fe5a9bd1889cafe42d58d046 498 Pfam PF12221 Bacterial membrane protein N terminal 1 82 3.2E-6 T 26-04-2017 IPR020980 Menbrane protein HflK, N-terminal A4V04_RS00300 ab7a0bf6fe5a9bd1889cafe42d58d046 498 TIGRFAM TIGR01933 hflK: HflK protein 171 445 1.7E-91 T 26-04-2017 IPR010201 HflK GO:0016021 A4V04_RS00300 ab7a0bf6fe5a9bd1889cafe42d58d046 498 Pfam PF01145 SPFH domain / Band 7 family 172 359 1.8E-27 T 26-04-2017 IPR001107 Band 7 domain A4V04_RS09175 28d6e7e17a8eb88abaa666fc9f69995a 424 Pfam PF00872 Transposase, Mutator family 36 401 3.0E-110 T 26-04-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4V04_RS09175 28d6e7e17a8eb88abaa666fc9f69995a 424 ProSitePatterns PS01007 Transposases, Mutator family, signature. 254 278 - T 26-04-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4V04_RS11205 f6edf71496ed45bf2388cacc49081e48 266 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 232 247 5.7E-5 T 26-04-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4V04_RS11205 f6edf71496ed45bf2388cacc49081e48 266 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 247 263 5.7E-5 T 26-04-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4V04_RS11205 f6edf71496ed45bf2388cacc49081e48 266 SUPERFAMILY SSF46689 225 265 1.08E-7 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS11205 f6edf71496ed45bf2388cacc49081e48 266 SMART SM00342 181 263 5.6E-19 T 26-04-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4V04_RS11205 f6edf71496ed45bf2388cacc49081e48 266 SUPERFAMILY SSF51182 33 109 1.4E-6 T 26-04-2017 IPR011051 RmlC-like cupin domain A4V04_RS11205 f6edf71496ed45bf2388cacc49081e48 266 Gene3D G3DSA:1.10.10.60 226 265 7.3E-10 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS11205 f6edf71496ed45bf2388cacc49081e48 266 Pfam PF12833 Helix-turn-helix domain 187 264 2.0E-19 T 26-04-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4V04_RS11205 f6edf71496ed45bf2388cacc49081e48 266 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 218 259 - T 26-04-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4V04_RS11205 f6edf71496ed45bf2388cacc49081e48 266 Gene3D G3DSA:1.10.10.60 183 217 2.1E-4 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS02430 a7be88b8d0727da8e13de99a9ddc08a6 441 PIRSF PIRSF004539 3 441 2.0E-152 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS02430 a7be88b8d0727da8e13de99a9ddc08a6 441 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 8 440 5.6E-133 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS02430 a7be88b8d0727da8e13de99a9ddc08a6 441 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 8 373 2.2E-132 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS01950 87759a3dfdd3c90b0eb7436ff8d341f0 247 SMART SM00382 58 230 1.4E-7 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS01950 87759a3dfdd3c90b0eb7436ff8d341f0 247 Pfam PF00005 ABC transporter 49 181 4.8E-18 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS01950 87759a3dfdd3c90b0eb7436ff8d341f0 247 Gene3D G3DSA:3.40.50.300 48 240 4.4E-41 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01950 87759a3dfdd3c90b0eb7436ff8d341f0 247 SUPERFAMILY SSF52540 48 241 3.34E-40 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05780 a204f808708a6187de0680a45eb09682 521 Pfam PF00117 Glutamine amidotransferase class-I 8 196 5.3E-35 T 26-04-2017 IPR017926 Glutamine amidotransferase A4V04_RS05780 a204f808708a6187de0680a45eb09682 521 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 3 521 54.859 T 26-04-2017 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A4V04_RS05780 a204f808708a6187de0680a45eb09682 521 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 209 521 1.4E-152 T 26-04-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4V04_RS05780 a204f808708a6187de0680a45eb09682 521 Pfam PF00958 GMP synthase C terminal domain 429 520 4.7E-44 T 26-04-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4V04_RS05780 a204f808708a6187de0680a45eb09682 521 SUPERFAMILY SSF52317 3 233 5.13E-52 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS05780 a204f808708a6187de0680a45eb09682 521 SUPERFAMILY SSF54810 401 521 1.7E-51 T 26-04-2017 A4V04_RS05780 a204f808708a6187de0680a45eb09682 521 SUPERFAMILY SSF52402 193 416 1.01E-56 T 26-04-2017 A4V04_RS05780 a204f808708a6187de0680a45eb09682 521 Pfam PF02540 NAD synthase 214 287 6.4E-8 T 26-04-2017 IPR022310 NAD/GMP synthase A4V04_RS05780 a204f808708a6187de0680a45eb09682 521 Gene3D G3DSA:3.30.300.10 397 521 2.6E-54 T 26-04-2017 A4V04_RS05780 a204f808708a6187de0680a45eb09682 521 Gene3D G3DSA:3.40.50.620 220 395 1.0E-59 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS05780 a204f808708a6187de0680a45eb09682 521 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 6 200 1.2E-70 T 26-04-2017 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4V04_RS05780 a204f808708a6187de0680a45eb09682 521 Gene3D G3DSA:3.40.50.880 2 219 6.4E-58 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS10640 873da29853023a134225c8f3ea8c4050 295 SUPERFAMILY SSF110849 40 128 1.28E-24 T 26-04-2017 IPR003115 ParB/Sulfiredoxin A4V04_RS10640 873da29853023a134225c8f3ea8c4050 295 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 36 211 6.9E-53 T 26-04-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 A4V04_RS10640 873da29853023a134225c8f3ea8c4050 295 SMART SM00470 36 126 6.4E-28 T 26-04-2017 IPR003115 ParB/Sulfiredoxin A4V04_RS10640 873da29853023a134225c8f3ea8c4050 295 Pfam PF02195 ParB-like nuclease domain 39 125 4.1E-24 T 26-04-2017 IPR003115 ParB/Sulfiredoxin A4V04_RS10640 873da29853023a134225c8f3ea8c4050 295 Gene3D G3DSA:3.90.1530.10 30 132 3.6E-35 T 26-04-2017 A4V04_RS10640 873da29853023a134225c8f3ea8c4050 295 SUPERFAMILY SSF109709 119 228 5.49E-33 T 26-04-2017 A4V04_RS11330 a1403e695a3872db7b8a9e537db4d68c 37 Pfam PF00444 Ribosomal protein L36 1 37 2.1E-18 T 26-04-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11330 a1403e695a3872db7b8a9e537db4d68c 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 5.2E-22 T 26-04-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11330 a1403e695a3872db7b8a9e537db4d68c 37 SUPERFAMILY SSF57840 1 37 4.45E-16 T 26-04-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11330 a1403e695a3872db7b8a9e537db4d68c 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 26-04-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11330 a1403e695a3872db7b8a9e537db4d68c 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.252 T 26-04-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS10935 23b9f41a54bff4db20ce2dbaa130007a 103 Pfam PF14537 Cytochrome c3 27 103 7.0E-13 T 26-04-2017 A4V04_RS10935 23b9f41a54bff4db20ce2dbaa130007a 103 SUPERFAMILY SSF48695 26 103 7.95E-10 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS10935 23b9f41a54bff4db20ce2dbaa130007a 103 Gene3D G3DSA:3.90.10.10 5 103 1.1E-10 T 26-04-2017 A4V04_RS09595 181687fc3cac7d59a9e64f8ff5a9eb6a 141 Pfam PF01230 HIT domain 12 98 9.5E-14 T 26-04-2017 IPR001310 Histidine triad (HIT) protein A4V04_RS09595 181687fc3cac7d59a9e64f8ff5a9eb6a 141 SUPERFAMILY SSF54197 1 118 9.42E-30 T 26-04-2017 IPR011146 HIT-like domain GO:0003824 A4V04_RS09595 181687fc3cac7d59a9e64f8ff5a9eb6a 141 Gene3D G3DSA:3.30.428.10 2 124 3.5E-32 T 26-04-2017 IPR011146 HIT-like domain GO:0003824 A4V04_RS09595 181687fc3cac7d59a9e64f8ff5a9eb6a 141 PIRSF PIRSF000714 1 140 1.1E-36 T 26-04-2017 IPR026026 Histidine triad hydrolase, Hint-type A4V04_RS04800 d4c2d2947ac0bb051cc03601b8eaced2 266 Hamap MF_00008 Thymidylate synthase [thyA]. 3 266 38.896 T 26-04-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 A4V04_RS04800 d4c2d2947ac0bb051cc03601b8eaced2 266 SUPERFAMILY SSF55831 5 266 3.14E-130 T 26-04-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 A4V04_RS04800 d4c2d2947ac0bb051cc03601b8eaced2 266 ProSitePatterns PS00091 Thymidylate synthase active site. 128 156 - T 26-04-2017 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 A4V04_RS04800 d4c2d2947ac0bb051cc03601b8eaced2 266 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 86 266 3.2E-95 T 26-04-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 A4V04_RS04800 d4c2d2947ac0bb051cc03601b8eaced2 266 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 5 87 2.9E-39 T 26-04-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 A4V04_RS04800 d4c2d2947ac0bb051cc03601b8eaced2 266 Pfam PF00303 Thymidylate synthase 5 266 4.8E-123 T 26-04-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 A4V04_RS04800 d4c2d2947ac0bb051cc03601b8eaced2 266 PRINTS PR00108 Thymidylate synthase family signature 44 65 1.4E-48 T 26-04-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 A4V04_RS04800 d4c2d2947ac0bb051cc03601b8eaced2 266 PRINTS PR00108 Thymidylate synthase family signature 143 158 1.4E-48 T 26-04-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 A4V04_RS04800 d4c2d2947ac0bb051cc03601b8eaced2 266 PRINTS PR00108 Thymidylate synthase family signature 117 136 1.4E-48 T 26-04-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 A4V04_RS04800 d4c2d2947ac0bb051cc03601b8eaced2 266 PRINTS PR00108 Thymidylate synthase family signature 161 187 1.4E-48 T 26-04-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 A4V04_RS04800 d4c2d2947ac0bb051cc03601b8eaced2 266 PRINTS PR00108 Thymidylate synthase family signature 199 216 1.4E-48 T 26-04-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 A4V04_RS04800 d4c2d2947ac0bb051cc03601b8eaced2 266 Gene3D G3DSA:3.30.572.10 4 266 4.7E-134 T 26-04-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 A4V04_RS06735 7223b1c45cbeaefdb6b7b45351a46a62 549 Pfam PF02335 Cytochrome c552 182 541 1.5E-57 T 26-04-2017 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 A4V04_RS06735 7223b1c45cbeaefdb6b7b45351a46a62 549 Gene3D G3DSA:1.20.140.10 435 540 1.9E-25 T 26-04-2017 A4V04_RS06735 7223b1c45cbeaefdb6b7b45351a46a62 549 SUPERFAMILY SSF48695 80 156 2.88E-84 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS06735 7223b1c45cbeaefdb6b7b45351a46a62 549 SUPERFAMILY SSF48695 194 542 2.88E-84 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS06735 7223b1c45cbeaefdb6b7b45351a46a62 549 SUPERFAMILY SSF48695 31 98 1.82E-8 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS06735 7223b1c45cbeaefdb6b7b45351a46a62 549 Gene3D G3DSA:1.10.1130.10 37 111 1.3E-9 T 26-04-2017 IPR012286 Tetrahaem cytochrome domain A4V04_RS06735 7223b1c45cbeaefdb6b7b45351a46a62 549 Gene3D G3DSA:1.10.780.10 359 434 4.6E-13 T 26-04-2017 A4V04_RS06735 7223b1c45cbeaefdb6b7b45351a46a62 549 Gene3D G3DSA:1.10.780.10 197 322 4.6E-13 T 26-04-2017 A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 SUPERFAMILY SSF48557 32 472 4.24E-95 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 Pfam PF14698 Argininosuccinate lyase C-terminal 371 443 1.8E-10 T 26-04-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 PRINTS PR00145 Argininosuccinate lyase family signature 282 298 1.1E-28 T 26-04-2017 A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 PRINTS PR00145 Argininosuccinate lyase family signature 108 130 1.1E-28 T 26-04-2017 A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 PRINTS PR00145 Argininosuccinate lyase family signature 149 169 1.1E-28 T 26-04-2017 A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 PRINTS PR00145 Argininosuccinate lyase family signature 200 216 1.1E-28 T 26-04-2017 A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 PRINTS PR00145 Argininosuccinate lyase family signature 238 262 1.1E-28 T 26-04-2017 A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 Pfam PF00206 Lyase 49 307 3.0E-46 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 Hamap MF_00006 Argininosuccinate lyase [argH]. 1 470 29.711 T 26-04-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 Gene3D G3DSA:1.10.275.10 37 113 3.0E-10 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 Gene3D G3DSA:1.10.40.30 383 437 6.8E-10 T 26-04-2017 A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 Gene3D G3DSA:1.20.200.10 114 382 3.8E-67 T 26-04-2017 A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 TIGRFAM TIGR00838 argH: argininosuccinate lyase 36 469 1.6E-110 T 26-04-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 PRINTS PR00149 Fumarate lyase superfamily signature 109 127 4.4E-20 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 PRINTS PR00149 Fumarate lyase superfamily signature 238 265 4.4E-20 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 PRINTS PR00149 Fumarate lyase superfamily signature 154 172 4.4E-20 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09650 15ec37921c96cb9748ab62cf64a4b093 504 PRINTS PR00149 Fumarate lyase superfamily signature 282 298 4.4E-20 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS12865 3f09a002b6533dcdf7d8ef7a0ce16f1d 147 Pfam PF04073 Aminoacyl-tRNA editing domain 8 129 6.6E-20 T 26-04-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4V04_RS12865 3f09a002b6533dcdf7d8ef7a0ce16f1d 147 Gene3D G3DSA:3.90.960.10 1 146 4.1E-43 T 26-04-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4V04_RS12865 3f09a002b6533dcdf7d8ef7a0ce16f1d 147 SUPERFAMILY SSF55826 3 142 1.05E-28 T 26-04-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4V04_RS01490 e1d050b73e252aa6a645ad7dc5525ab5 366 Pfam PF00155 Aminotransferase class I and II 37 362 2.2E-58 T 26-04-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4V04_RS01490 e1d050b73e252aa6a645ad7dc5525ab5 366 Gene3D G3DSA:3.90.1150.10 270 366 4.6E-22 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS01490 e1d050b73e252aa6a645ad7dc5525ab5 366 SUPERFAMILY SSF53383 22 366 2.75E-80 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS01490 e1d050b73e252aa6a645ad7dc5525ab5 366 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 227 236 - T 26-04-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 A4V04_RS01490 e1d050b73e252aa6a645ad7dc5525ab5 366 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 7 366 57.521 T 26-04-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A4V04_RS01490 e1d050b73e252aa6a645ad7dc5525ab5 366 Gene3D G3DSA:3.40.640.10 51 269 4.6E-73 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS01490 e1d050b73e252aa6a645ad7dc5525ab5 366 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 12 364 6.7E-105 T 26-04-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A4V04_RS10015 1c2751e567a53b90714b23490b0b44dd 312 Gene3D G3DSA:2.60.260.20 123 206 4.5E-16 T 26-04-2017 A4V04_RS10015 1c2751e567a53b90714b23490b0b44dd 312 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 26-04-2017 IPR018253 DnaJ domain, conserved site A4V04_RS10015 1c2751e567a53b90714b23490b0b44dd 312 SMART SM00271 4 61 8.1E-28 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS10015 1c2751e567a53b90714b23490b0b44dd 312 Gene3D G3DSA:2.60.260.20 211 286 1.3E-18 T 26-04-2017 A4V04_RS10015 1c2751e567a53b90714b23490b0b44dd 312 SUPERFAMILY SSF49493 124 207 7.98E-14 T 26-04-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4V04_RS10015 1c2751e567a53b90714b23490b0b44dd 312 Gene3D G3DSA:1.10.287.110 2 90 6.5E-33 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS10015 1c2751e567a53b90714b23490b0b44dd 312 SUPERFAMILY SSF46565 1 101 8.9E-33 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS10015 1c2751e567a53b90714b23490b0b44dd 312 Pfam PF00226 DnaJ domain 5 66 5.5E-25 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS10015 1c2751e567a53b90714b23490b0b44dd 312 SUPERFAMILY SSF49493 211 297 1.01E-20 T 26-04-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4V04_RS10015 1c2751e567a53b90714b23490b0b44dd 312 Pfam PF01556 DnaJ C terminal domain 130 286 2.2E-29 T 26-04-2017 IPR002939 Chaperone DnaJ, C-terminal A4V04_RS10015 1c2751e567a53b90714b23490b0b44dd 312 PRINTS PR00625 DnaJ domain signature 41 61 3.8E-24 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS10015 1c2751e567a53b90714b23490b0b44dd 312 PRINTS PR00625 DnaJ domain signature 25 40 3.8E-24 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS10015 1c2751e567a53b90714b23490b0b44dd 312 PRINTS PR00625 DnaJ domain signature 61 80 3.8E-24 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS10015 1c2751e567a53b90714b23490b0b44dd 312 PRINTS PR00625 DnaJ domain signature 7 25 3.8E-24 T 26-04-2017 IPR001623 DnaJ domain A4V04_RS01410 9ddb61867ca9d8510b3115416cbd27fc 599 Pfam PF01609 Transposase DDE domain 244 509 3.2E-11 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS01410 9ddb61867ca9d8510b3115416cbd27fc 599 SUPERFAMILY SSF53098 178 386 1.74E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS01410 9ddb61867ca9d8510b3115416cbd27fc 599 SUPERFAMILY SSF53098 448 522 1.74E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS06385 9ddb61867ca9d8510b3115416cbd27fc 599 Pfam PF01609 Transposase DDE domain 244 509 3.2E-11 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS06385 9ddb61867ca9d8510b3115416cbd27fc 599 SUPERFAMILY SSF53098 178 386 1.74E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS06385 9ddb61867ca9d8510b3115416cbd27fc 599 SUPERFAMILY SSF53098 448 522 1.74E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS07970 6da52a1b18bceef9ec3a0c0a4ddd5fb8 192 Gene3D G3DSA:3.30.70.20 7 72 1.4E-25 T 26-04-2017 A4V04_RS07970 6da52a1b18bceef9ec3a0c0a4ddd5fb8 192 Gene3D G3DSA:3.30.70.20 139 189 1.4E-25 T 26-04-2017 A4V04_RS07970 6da52a1b18bceef9ec3a0c0a4ddd5fb8 192 Gene3D G3DSA:3.30.70.20 73 102 2.5E-12 T 26-04-2017 A4V04_RS07970 6da52a1b18bceef9ec3a0c0a4ddd5fb8 192 Pfam PF13247 4Fe-4S dicluster domain 66 156 4.4E-18 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07970 6da52a1b18bceef9ec3a0c0a4ddd5fb8 192 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS07970 6da52a1b18bceef9ec3a0c0a4ddd5fb8 192 Gene3D G3DSA:3.30.70.20 103 138 5.4E-8 T 26-04-2017 A4V04_RS07970 6da52a1b18bceef9ec3a0c0a4ddd5fb8 192 SUPERFAMILY SSF54862 5 189 1.17E-51 T 26-04-2017 A4V04_RS01090 9843eb9bcfdf2b88a80876a19ad0c7a9 315 Gene3D G3DSA:3.40.190.10 189 278 7.8E-19 T 26-04-2017 A4V04_RS01090 9843eb9bcfdf2b88a80876a19ad0c7a9 315 SUPERFAMILY SSF53850 106 304 1.68E-26 T 26-04-2017 A4V04_RS01090 9843eb9bcfdf2b88a80876a19ad0c7a9 315 SUPERFAMILY SSF46785 15 94 2.83E-11 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01090 9843eb9bcfdf2b88a80876a19ad0c7a9 315 Pfam PF03466 LysR substrate binding domain 106 303 2.9E-31 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS01090 9843eb9bcfdf2b88a80876a19ad0c7a9 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 71 1.2E-9 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS01090 9843eb9bcfdf2b88a80876a19ad0c7a9 315 Gene3D G3DSA:1.10.10.10 15 93 9.8E-15 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01090 9843eb9bcfdf2b88a80876a19ad0c7a9 315 Gene3D G3DSA:3.40.190.10 109 188 6.7E-11 T 26-04-2017 A4V04_RS04655 21b14814b7813ec41e8d7b375f26b3f3 393 Pfam PF07687 Peptidase dimerisation domain 175 280 6.7E-20 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS04655 21b14814b7813ec41e8d7b375f26b3f3 393 SUPERFAMILY SSF55031 178 280 6.54E-16 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS04655 21b14814b7813ec41e8d7b375f26b3f3 393 SUPERFAMILY SSF53187 304 387 3.29E-52 T 26-04-2017 A4V04_RS04655 21b14814b7813ec41e8d7b375f26b3f3 393 SUPERFAMILY SSF53187 7 177 3.29E-52 T 26-04-2017 A4V04_RS04655 21b14814b7813ec41e8d7b375f26b3f3 393 Pfam PF01546 Peptidase family M20/M25/M40 70 386 5.7E-29 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS04655 21b14814b7813ec41e8d7b375f26b3f3 393 Gene3D G3DSA:3.30.70.360 187 279 8.1E-20 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS04655 21b14814b7813ec41e8d7b375f26b3f3 393 Gene3D G3DSA:3.40.630.10 329 389 2.8E-51 T 26-04-2017 A4V04_RS04655 21b14814b7813ec41e8d7b375f26b3f3 393 Gene3D G3DSA:3.40.630.10 8 186 2.8E-51 T 26-04-2017 A4V04_RS08195 72757af8cfc83cb34c98409f80264598 1013 SMART SM00487 235 431 1.2E-15 T 26-04-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4V04_RS08195 72757af8cfc83cb34c98409f80264598 1013 Pfam PF13091 PLD-like domain 90 193 8.5E-11 T 26-04-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 A4V04_RS08195 72757af8cfc83cb34c98409f80264598 1013 SUPERFAMILY SSF56024 95 197 5.3E-8 T 26-04-2017 A4V04_RS08195 72757af8cfc83cb34c98409f80264598 1013 SMART SM00490 496 581 4.6E-11 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS08195 72757af8cfc83cb34c98409f80264598 1013 Pfam PF04851 Type III restriction enzyme, res subunit 237 403 9.2E-28 T 26-04-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4V04_RS08195 72757af8cfc83cb34c98409f80264598 1013 Pfam PF11907 Domain of unknown function (DUF3427) 724 1010 2.3E-71 T 26-04-2017 IPR021835 Protein of unknown function DUF3427 A4V04_RS08195 72757af8cfc83cb34c98409f80264598 1013 Gene3D G3DSA:3.30.870.10 98 201 1.4E-9 T 26-04-2017 A4V04_RS08195 72757af8cfc83cb34c98409f80264598 1013 Pfam PF00271 Helicase conserved C-terminal domain 481 579 3.0E-13 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS08195 72757af8cfc83cb34c98409f80264598 1013 Gene3D G3DSA:3.40.50.300 462 616 7.2E-24 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08195 72757af8cfc83cb34c98409f80264598 1013 Gene3D G3DSA:3.40.50.300 232 411 3.8E-25 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08195 72757af8cfc83cb34c98409f80264598 1013 SUPERFAMILY SSF52540 301 598 8.52E-42 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11160 eb596d4ab8a30010c83e723eb183ba50 125 Gene3D G3DSA:2.40.50.140 1 123 1.7E-66 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS11160 eb596d4ab8a30010c83e723eb183ba50 125 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 26-04-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11160 eb596d4ab8a30010c83e723eb183ba50 125 PRINTS PR01034 Ribosomal protein S12 signature 110 122 8.6E-61 T 26-04-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11160 eb596d4ab8a30010c83e723eb183ba50 125 PRINTS PR01034 Ribosomal protein S12 signature 27 42 8.6E-61 T 26-04-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11160 eb596d4ab8a30010c83e723eb183ba50 125 PRINTS PR01034 Ribosomal protein S12 signature 94 110 8.6E-61 T 26-04-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11160 eb596d4ab8a30010c83e723eb183ba50 125 PRINTS PR01034 Ribosomal protein S12 signature 77 94 8.6E-61 T 26-04-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11160 eb596d4ab8a30010c83e723eb183ba50 125 PRINTS PR01034 Ribosomal protein S12 signature 42 57 8.6E-61 T 26-04-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11160 eb596d4ab8a30010c83e723eb183ba50 125 PRINTS PR01034 Ribosomal protein S12 signature 58 77 8.6E-61 T 26-04-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11160 eb596d4ab8a30010c83e723eb183ba50 125 SUPERFAMILY SSF50249 2 124 1.29E-52 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS11160 eb596d4ab8a30010c83e723eb183ba50 125 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 6.7E-71 T 26-04-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11160 eb596d4ab8a30010c83e723eb183ba50 125 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.97 T 26-04-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11160 eb596d4ab8a30010c83e723eb183ba50 125 PIRSF PIRSF002133 1 124 5.2E-55 T 26-04-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11160 eb596d4ab8a30010c83e723eb183ba50 125 Pfam PF00164 Ribosomal protein S12/S23 3 123 1.1E-43 T 26-04-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS04045 6ecbd70ed80c1725755a50d0882c336b 252 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 252 68.295 T 26-04-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 A4V04_RS04045 6ecbd70ed80c1725755a50d0882c336b 252 SUPERFAMILY SSF55729 10 236 1.27E-69 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS04045 6ecbd70ed80c1725755a50d0882c336b 252 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 44 227 1.6E-43 T 26-04-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 A4V04_RS04045 6ecbd70ed80c1725755a50d0882c336b 252 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 40 216 6.8E-59 T 26-04-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 A4V04_RS10185 b79303411a1f8d92f31eee4c37457b53 468 Pfam PF01979 Amidohydrolase family 327 419 2.7E-9 T 26-04-2017 IPR006680 Amidohydrolase-related GO:0016787 A4V04_RS10185 b79303411a1f8d92f31eee4c37457b53 468 Gene3D G3DSA:3.20.20.140 286 287 4.3E-21 T 26-04-2017 A4V04_RS10185 b79303411a1f8d92f31eee4c37457b53 468 Gene3D G3DSA:3.20.20.140 62 246 4.3E-21 T 26-04-2017 A4V04_RS10185 b79303411a1f8d92f31eee4c37457b53 468 Gene3D G3DSA:3.20.20.140 343 412 4.3E-21 T 26-04-2017 A4V04_RS10185 b79303411a1f8d92f31eee4c37457b53 468 SUPERFAMILY SSF51338 1 55 4.17E-20 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS10185 b79303411a1f8d92f31eee4c37457b53 468 SUPERFAMILY SSF51338 393 431 4.17E-20 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS10185 b79303411a1f8d92f31eee4c37457b53 468 Gene3D G3DSA:2.30.40.10 1 61 1.2E-18 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS10185 b79303411a1f8d92f31eee4c37457b53 468 SUPERFAMILY SSF51556 56 249 1.15E-20 T 26-04-2017 IPR032466 Metal-dependent hydrolase A4V04_RS10185 b79303411a1f8d92f31eee4c37457b53 468 SUPERFAMILY SSF51556 308 393 1.15E-20 T 26-04-2017 IPR032466 Metal-dependent hydrolase A4V04_RS11890 cfaa1a5afecbce0d9784b48218ee2312 119 SUPERFAMILY SSF48695 34 115 1.59E-13 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS11890 cfaa1a5afecbce0d9784b48218ee2312 119 Pfam PF14537 Cytochrome c3 31 112 3.5E-18 T 26-04-2017 A4V04_RS11890 cfaa1a5afecbce0d9784b48218ee2312 119 Gene3D G3DSA:1.10.1130.10 30 113 7.4E-12 T 26-04-2017 IPR012286 Tetrahaem cytochrome domain A4V04_RS05975 25bb652cde9e9629d09d1fd42e06618c 633 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS05975 25bb652cde9e9629d09d1fd42e06618c 633 Pfam PF00005 ABC transporter 328 459 7.8E-23 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS05975 25bb652cde9e9629d09d1fd42e06618c 633 Pfam PF00005 ABC transporter 22 178 4.7E-23 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS05975 25bb652cde9e9629d09d1fd42e06618c 633 SUPERFAMILY SSF52540 299 513 1.93E-43 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05975 25bb652cde9e9629d09d1fd42e06618c 633 Gene3D G3DSA:3.40.50.300 316 545 1.6E-42 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05975 25bb652cde9e9629d09d1fd42e06618c 633 SMART SM00382 337 503 6.1E-9 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS05975 25bb652cde9e9629d09d1fd42e06618c 633 SMART SM00382 26 223 9.6E-13 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS05975 25bb652cde9e9629d09d1fd42e06618c 633 Pfam PF12848 ABC transporter 217 293 4.7E-24 T 26-04-2017 IPR032781 ABC-transporter extension domain A4V04_RS05975 25bb652cde9e9629d09d1fd42e06618c 633 SUPERFAMILY SSF52540 2 87 4.02E-44 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05975 25bb652cde9e9629d09d1fd42e06618c 633 SUPERFAMILY SSF52540 119 243 4.02E-44 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05975 25bb652cde9e9629d09d1fd42e06618c 633 Gene3D G3DSA:3.40.50.300 1 265 6.2E-47 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05975 25bb652cde9e9629d09d1fd42e06618c 633 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS06195 5c4be26650a6dee14abb9ca229ecac8b 283 SUPERFAMILY SSF53335 4 258 4.04E-58 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS06195 5c4be26650a6dee14abb9ca229ecac8b 283 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 32 38 - T 26-04-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4V04_RS06195 5c4be26650a6dee14abb9ca229ecac8b 283 Gene3D G3DSA:3.40.50.150 9 258 3.9E-60 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS06195 5c4be26650a6dee14abb9ca229ecac8b 283 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 215 233 2.6E-29 T 26-04-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4V04_RS06195 5c4be26650a6dee14abb9ca229ecac8b 283 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 61 81 2.6E-29 T 26-04-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4V04_RS06195 5c4be26650a6dee14abb9ca229ecac8b 283 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 196 213 2.6E-29 T 26-04-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4V04_RS06195 5c4be26650a6dee14abb9ca229ecac8b 283 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 238 258 2.6E-29 T 26-04-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4V04_RS06195 5c4be26650a6dee14abb9ca229ecac8b 283 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 28 42 2.6E-29 T 26-04-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4V04_RS06195 5c4be26650a6dee14abb9ca229ecac8b 283 Pfam PF01555 DNA methylase 30 251 2.5E-40 T 26-04-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A4V04_RS01235 081bd7b1f3d1133b467d9c5b8952a485 558 Gene3D G3DSA:3.30.70.1450 306 366 4.8E-7 T 26-04-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4V04_RS01235 081bd7b1f3d1133b467d9c5b8952a485 558 SUPERFAMILY SSF116726 285 367 1.96E-11 T 26-04-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4V04_RS01235 081bd7b1f3d1133b467d9c5b8952a485 558 SUPERFAMILY SSF116726 212 280 6.41E-5 T 26-04-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4V04_RS01235 081bd7b1f3d1133b467d9c5b8952a485 558 Pfam PF06826 Predicted Permease Membrane Region 21 184 8.7E-38 T 26-04-2017 IPR006512 YidE/YbjL duplication A4V04_RS01235 081bd7b1f3d1133b467d9c5b8952a485 558 Pfam PF06826 Predicted Permease Membrane Region 380 550 3.1E-39 T 26-04-2017 IPR006512 YidE/YbjL duplication A4V04_RS01235 081bd7b1f3d1133b467d9c5b8952a485 558 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 384 538 1.7E-37 T 26-04-2017 IPR006512 YidE/YbjL duplication A4V04_RS01235 081bd7b1f3d1133b467d9c5b8952a485 558 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 26 171 7.2E-30 T 26-04-2017 IPR006512 YidE/YbjL duplication A4V04_RS06780 e3c1877f50298750bf553337ad8ae587 227 Pfam PF00005 ABC transporter 24 165 4.8E-28 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS06780 e3c1877f50298750bf553337ad8ae587 227 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 8 203 1.6E-64 T 26-04-2017 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 A4V04_RS06780 e3c1877f50298750bf553337ad8ae587 227 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS06780 e3c1877f50298750bf553337ad8ae587 227 SMART SM00382 32 213 1.2E-8 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS06780 e3c1877f50298750bf553337ad8ae587 227 SUPERFAMILY SSF52540 6 218 3.63E-41 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06780 e3c1877f50298750bf553337ad8ae587 227 Gene3D G3DSA:3.40.50.300 4 218 1.1E-40 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00370 7b3ad6db11f6b2b47b80ea54f6baf532 409 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 21 384 1.4E-93 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS00370 7b3ad6db11f6b2b47b80ea54f6baf532 409 Gene3D G3DSA:3.30.70.360 189 307 3.5E-33 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS00370 7b3ad6db11f6b2b47b80ea54f6baf532 409 Gene3D G3DSA:3.40.630.10 308 397 1.3E-82 T 26-04-2017 A4V04_RS00370 7b3ad6db11f6b2b47b80ea54f6baf532 409 Gene3D G3DSA:3.40.630.10 5 186 1.3E-82 T 26-04-2017 A4V04_RS00370 7b3ad6db11f6b2b47b80ea54f6baf532 409 Pfam PF01546 Peptidase family M20/M25/M40 80 391 2.1E-28 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS00370 7b3ad6db11f6b2b47b80ea54f6baf532 409 Pfam PF07687 Peptidase dimerisation domain 193 288 1.3E-4 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS00370 7b3ad6db11f6b2b47b80ea54f6baf532 409 SUPERFAMILY SSF53187 9 205 5.99E-67 T 26-04-2017 A4V04_RS00370 7b3ad6db11f6b2b47b80ea54f6baf532 409 SUPERFAMILY SSF53187 308 396 5.99E-67 T 26-04-2017 A4V04_RS00370 7b3ad6db11f6b2b47b80ea54f6baf532 409 SUPERFAMILY SSF55031 191 303 5.68E-26 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS00370 7b3ad6db11f6b2b47b80ea54f6baf532 409 PIRSF PIRSF005962 6 399 7.8E-110 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS00225 37587aad7166ebe71fc73a6758b4290e 250 Gene3D G3DSA:3.10.350.10 36 82 9.2E-17 T 26-04-2017 IPR018392 LysM domain A4V04_RS00225 37587aad7166ebe71fc73a6758b4290e 250 SMART SM00257 38 82 1.2E-13 T 26-04-2017 IPR018392 LysM domain A4V04_RS00225 37587aad7166ebe71fc73a6758b4290e 250 Pfam PF01551 Peptidase family M23 151 243 1.0E-28 T 26-04-2017 IPR016047 Peptidase M23 A4V04_RS00225 37587aad7166ebe71fc73a6758b4290e 250 Pfam PF01476 LysM domain 39 81 2.0E-11 T 26-04-2017 IPR018392 LysM domain A4V04_RS00225 37587aad7166ebe71fc73a6758b4290e 250 Gene3D G3DSA:2.70.70.10 112 248 5.6E-39 T 26-04-2017 A4V04_RS00225 37587aad7166ebe71fc73a6758b4290e 250 SUPERFAMILY SSF51261 38 247 3.14E-43 T 26-04-2017 IPR011055 Duplicated hybrid motif A4V04_RS10860 79bb51420ec7099b42fee75ec04fb3bb 218 SMART SM00862 145 216 2.1E-23 T 26-04-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4V04_RS10860 79bb51420ec7099b42fee75ec04fb3bb 218 Gene3D G3DSA:1.10.10.10 123 217 1.1E-27 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10860 79bb51420ec7099b42fee75ec04fb3bb 218 SUPERFAMILY SSF52172 1 173 1.06E-36 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS10860 79bb51420ec7099b42fee75ec04fb3bb 218 SMART SM00448 1 112 1.3E-35 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS10860 79bb51420ec7099b42fee75ec04fb3bb 218 Gene3D G3DSA:3.40.50.2300 1 120 5.3E-36 T 26-04-2017 A4V04_RS10860 79bb51420ec7099b42fee75ec04fb3bb 218 Pfam PF00072 Response regulator receiver domain 3 112 1.5E-25 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS10860 79bb51420ec7099b42fee75ec04fb3bb 218 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 1.6E-21 T 26-04-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4V04_RS01155 0e0da5d62953d107b1ab94e67a28f7f8 268 Gene3D G3DSA:3.40.50.720 1 162 1.7E-51 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01155 0e0da5d62953d107b1ab94e67a28f7f8 268 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 149 166 - T 26-04-2017 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS01155 0e0da5d62953d107b1ab94e67a28f7f8 268 SUPERFAMILY SSF51735 1 126 7.46E-44 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01155 0e0da5d62953d107b1ab94e67a28f7f8 268 SUPERFAMILY SSF51735 235 266 7.46E-44 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01155 0e0da5d62953d107b1ab94e67a28f7f8 268 SUPERFAMILY SSF55347 128 235 6.1E-34 T 26-04-2017 A4V04_RS01155 0e0da5d62953d107b1ab94e67a28f7f8 268 PIRSF PIRSF000161 1 267 9.0E-88 T 26-04-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS01155 0e0da5d62953d107b1ab94e67a28f7f8 268 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 264 1.3E-84 T 26-04-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS01155 0e0da5d62953d107b1ab94e67a28f7f8 268 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 128 263 1.2E-41 T 26-04-2017 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS01155 0e0da5d62953d107b1ab94e67a28f7f8 268 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 125 2.2E-34 T 26-04-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS01155 0e0da5d62953d107b1ab94e67a28f7f8 268 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 264 32.24 T 26-04-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4V04_RS02160 ba03f592d7c39cb9c9800ad377096f8e 580 SUPERFAMILY SSF56425 389 522 2.93E-28 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02160 ba03f592d7c39cb9c9800ad377096f8e 580 SUPERFAMILY SSF51905 130 385 1.5E-48 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02160 ba03f592d7c39cb9c9800ad377096f8e 580 SUPERFAMILY SSF51905 521 577 1.5E-48 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02160 ba03f592d7c39cb9c9800ad377096f8e 580 Pfam PF04205 FMN-binding domain 39 110 5.6E-15 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS02160 ba03f592d7c39cb9c9800ad377096f8e 580 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 139 573 6.0E-86 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS02160 ba03f592d7c39cb9c9800ad377096f8e 580 Gene3D G3DSA:3.90.700.10 393 513 6.7E-29 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02160 ba03f592d7c39cb9c9800ad377096f8e 580 Gene3D G3DSA:3.50.50.60 126 368 9.3E-73 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02160 ba03f592d7c39cb9c9800ad377096f8e 580 Gene3D G3DSA:3.50.50.60 518 578 9.3E-73 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02160 ba03f592d7c39cb9c9800ad377096f8e 580 SMART SM00900 39 113 1.8E-17 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS02160 ba03f592d7c39cb9c9800ad377096f8e 580 Pfam PF00890 FAD binding domain 139 549 1.7E-56 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11260 3e3450c345fa3178ed58ea1a695f40a8 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 26-04-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11260 3e3450c345fa3178ed58ea1a695f40a8 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 26-04-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11260 3e3450c345fa3178ed58ea1a695f40a8 138 SUPERFAMILY SSF54686 1 135 6.54E-54 T 26-04-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A4V04_RS11260 3e3450c345fa3178ed58ea1a695f40a8 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.805 T 26-04-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11260 3e3450c345fa3178ed58ea1a695f40a8 138 Gene3D G3DSA:3.90.1170.10 23 135 8.5E-52 T 26-04-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A4V04_RS11260 3e3450c345fa3178ed58ea1a695f40a8 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 1.1E-58 T 26-04-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11260 3e3450c345fa3178ed58ea1a695f40a8 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 7.6E-40 T 26-04-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11260 3e3450c345fa3178ed58ea1a695f40a8 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 7.6E-40 T 26-04-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11260 3e3450c345fa3178ed58ea1a695f40a8 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 7.6E-40 T 26-04-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11260 3e3450c345fa3178ed58ea1a695f40a8 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 7.6E-40 T 26-04-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11260 3e3450c345fa3178ed58ea1a695f40a8 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 5.1E-48 T 26-04-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A4V04_RS01735 22ce2edaca31a197c80f74c3a35b0824 381 SUPERFAMILY SSF56935 23 381 9.3E-54 T 26-04-2017 A4V04_RS01735 22ce2edaca31a197c80f74c3a35b0824 381 Pfam PF13609 Gram-negative porin 12 352 2.5E-36 T 26-04-2017 A4V04_RS01735 22ce2edaca31a197c80f74c3a35b0824 381 Gene3D G3DSA:2.40.160.10 22 381 8.6E-63 T 26-04-2017 IPR023614 Porin domain A4V04_RS05360 dcdc67b814c6ac4f33ef722f27d86a1f 253 Pfam PF02535 ZIP Zinc transporter 108 244 6.3E-29 T 26-04-2017 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 A4V04_RS05360 dcdc67b814c6ac4f33ef722f27d86a1f 253 Pfam PF02535 ZIP Zinc transporter 7 101 1.9E-9 T 26-04-2017 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 A4V04_RS10755 0cda68fb8b83eb3a402a0458d2ec7533 314 SMART SM00978 184 312 2.4E-19 T 26-04-2017 IPR007379 Tim44-like domain A4V04_RS10755 0cda68fb8b83eb3a402a0458d2ec7533 314 Pfam PF04280 Tim44-like domain 193 249 5.2E-9 T 26-04-2017 IPR007379 Tim44-like domain A4V04_RS10755 0cda68fb8b83eb3a402a0458d2ec7533 314 SUPERFAMILY SSF54427 193 313 2.92E-11 T 26-04-2017 IPR032710 NTF2-like domain A4V04_RS08780 3542922b5648991b0c110080978adaf2 150 Pfam PF03652 Holliday junction resolvase 21 142 3.1E-31 T 26-04-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A4V04_RS08780 3542922b5648991b0c110080978adaf2 150 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 20 145 19.205 T 26-04-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A4V04_RS08780 3542922b5648991b0c110080978adaf2 150 SMART SM00732 20 120 4.3E-20 T 26-04-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 A4V04_RS08780 3542922b5648991b0c110080978adaf2 150 SUPERFAMILY SSF53098 21 142 1.52E-31 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS08780 3542922b5648991b0c110080978adaf2 150 Gene3D G3DSA:3.30.420.140 21 143 3.4E-32 T 26-04-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 A4V04_RS08780 3542922b5648991b0c110080978adaf2 150 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 23 141 6.0E-23 T 26-04-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A4V04_RS09880 58e8d921cd6c918b719d40292e2e1230 236 Gene3D G3DSA:3.30.70.20 131 163 6.8E-13 T 26-04-2017 A4V04_RS09880 58e8d921cd6c918b719d40292e2e1230 236 SUPERFAMILY SSF54862 57 234 1.88E-34 T 26-04-2017 A4V04_RS09880 58e8d921cd6c918b719d40292e2e1230 236 Gene3D G3DSA:3.30.70.20 58 130 7.1E-5 T 26-04-2017 A4V04_RS09880 58e8d921cd6c918b719d40292e2e1230 236 Gene3D G3DSA:3.30.70.20 164 213 7.8E-15 T 26-04-2017 A4V04_RS09880 58e8d921cd6c918b719d40292e2e1230 236 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 157 168 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS09880 58e8d921cd6c918b719d40292e2e1230 236 Pfam PF13247 4Fe-4S dicluster domain 120 203 2.2E-10 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS04395 f20518c79c78e7eede79bdd527664525 381 TIGRFAM TIGR01975 isoAsp_dipep: beta-aspartyl peptidase 6 380 3.6E-113 T 26-04-2017 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 A4V04_RS04395 f20518c79c78e7eede79bdd527664525 381 SUPERFAMILY SSF51338 338 370 1.31E-15 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS04395 f20518c79c78e7eede79bdd527664525 381 SUPERFAMILY SSF51338 4 57 1.31E-15 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS04395 f20518c79c78e7eede79bdd527664525 381 Gene3D G3DSA:2.30.40.10 347 376 5.2E-14 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS04395 f20518c79c78e7eede79bdd527664525 381 Gene3D G3DSA:2.30.40.10 3 58 5.2E-14 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS04395 f20518c79c78e7eede79bdd527664525 381 Pfam PF01979 Amidohydrolase family 53 367 2.7E-13 T 26-04-2017 IPR006680 Amidohydrolase-related GO:0016787 A4V04_RS04395 f20518c79c78e7eede79bdd527664525 381 Gene3D G3DSA:2.30.40.10 323 346 6.1E-4 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS04395 f20518c79c78e7eede79bdd527664525 381 SUPERFAMILY SSF51556 57 338 7.27E-53 T 26-04-2017 IPR032466 Metal-dependent hydrolase A4V04_RS04395 f20518c79c78e7eede79bdd527664525 381 PIRSF PIRSF001238 4 381 1.7E-127 T 26-04-2017 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 A4V04_RS04395 f20518c79c78e7eede79bdd527664525 381 Gene3D G3DSA:3.20.20.140 59 322 6.0E-99 T 26-04-2017 A4V04_RS00055 7c441cddbe39f215683f1b06ea48b77f 573 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 24 565 1.6E-136 T 26-04-2017 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 A4V04_RS00055 7c441cddbe39f215683f1b06ea48b77f 573 Pfam PF02272 DHHA1 domain 378 449 1.4E-12 T 26-04-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A4V04_RS00055 7c441cddbe39f215683f1b06ea48b77f 573 Pfam PF01368 DHH family 73 204 5.2E-11 T 26-04-2017 IPR001667 DDH domain A4V04_RS00055 7c441cddbe39f215683f1b06ea48b77f 573 SUPERFAMILY SSF64182 48 452 6.28E-100 T 26-04-2017 A4V04_RS06670 b128e4b91286e16ec56e296b169237d2 465 SUPERFAMILY SSF56037 346 451 3.4E-9 T 26-04-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 A4V04_RS06670 b128e4b91286e16ec56e296b169237d2 465 SMART SM00977 386 459 0.0094 T 26-04-2017 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A4V04_RS06670 b128e4b91286e16ec56e296b169237d2 465 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 39 220 8.1E-56 T 26-04-2017 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A4V04_RS06670 b128e4b91286e16ec56e296b169237d2 465 Pfam PF09179 TilS substrate binding domain 267 315 3.6E-8 T 26-04-2017 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A4V04_RS06670 b128e4b91286e16ec56e296b169237d2 465 SUPERFAMILY SSF52402 38 249 6.98E-53 T 26-04-2017 A4V04_RS06670 b128e4b91286e16ec56e296b169237d2 465 Gene3D G3DSA:3.40.50.620 35 195 1.9E-13 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS06670 b128e4b91286e16ec56e296b169237d2 465 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 29 324 22.965 T 26-04-2017 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A4V04_RS06670 b128e4b91286e16ec56e296b169237d2 465 Pfam PF11734 TilS substrate C-terminal domain 392 441 1.4E-8 T 26-04-2017 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A4V04_RS06670 b128e4b91286e16ec56e296b169237d2 465 Pfam PF01171 PP-loop family 39 215 4.5E-53 T 26-04-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A4V04_RS06670 b128e4b91286e16ec56e296b169237d2 465 SUPERFAMILY SSF82829 253 313 4.32E-9 T 26-04-2017 A4V04_RS04735 b9470becbb64d84fab6cc1673f2bdcf4 142 Gene3D G3DSA:3.40.50.10110 8 140 2.4E-27 T 26-04-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 A4V04_RS04735 b9470becbb64d84fab6cc1673f2bdcf4 142 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 135 2.4E-25 T 26-04-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 A4V04_RS04735 b9470becbb64d84fab6cc1673f2bdcf4 142 SUPERFAMILY SSF102400 12 140 4.97E-24 T 26-04-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 A4V04_RS03825 79f091f09c756f2948f816f48ed7437f 221 SUPERFAMILY SSF48150 40 204 9.77E-30 T 26-04-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4V04_RS03825 79f091f09c756f2948f816f48ed7437f 221 Gene3D G3DSA:1.10.1670.10 152 203 2.6E-5 T 26-04-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A4V04_RS03825 79f091f09c756f2948f816f48ed7437f 221 Gene3D G3DSA:1.10.340.30 43 151 6.5E-24 T 26-04-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4V04_RS03825 79f091f09c756f2948f816f48ed7437f 221 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 47 184 1.8E-10 T 26-04-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4V04_RS03825 79f091f09c756f2948f816f48ed7437f 221 SMART SM00478 51 203 0.0042 T 26-04-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4V04_RS04600 dcccfaa0e2cd7e66d7a06bc7f6646250 126 Gene3D G3DSA:1.10.10.10 77 115 3.3E-7 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04600 dcccfaa0e2cd7e66d7a06bc7f6646250 126 SUPERFAMILY SSF46689 17 88 4.12E-5 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS04600 dcccfaa0e2cd7e66d7a06bc7f6646250 126 SUPERFAMILY SSF46689 72 119 8.24E-7 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS04600 dcccfaa0e2cd7e66d7a06bc7f6646250 126 Pfam PF13384 Homeodomain-like domain 74 120 4.0E-8 T 26-04-2017 A4V04_RS01825 ccca652dc0d6a191adf3ede8bdc2c325 251 Pfam PF06586 TraK protein 9 243 9.1E-26 T 26-04-2017 IPR010563 Pilus assembly TraK A4V04_RS07975 900eeeceb3f61862f043e0a0b1261982 842 Pfam PF01568 Molydopterin dinucleotide binding domain 739 789 1.0E-9 T 26-04-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4V04_RS07975 900eeeceb3f61862f043e0a0b1261982 842 SUPERFAMILY SSF50692 666 796 6.1E-14 T 26-04-2017 IPR009010 Aspartate decarboxylase-like domain A4V04_RS07975 900eeeceb3f61862f043e0a0b1261982 842 SMART SM00926 33 90 0.0098 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS07975 900eeeceb3f61862f043e0a0b1261982 842 SUPERFAMILY SSF53706 32 318 1.44E-114 T 26-04-2017 A4V04_RS07975 900eeeceb3f61862f043e0a0b1261982 842 SUPERFAMILY SSF53706 345 680 1.44E-114 T 26-04-2017 A4V04_RS07975 900eeeceb3f61862f043e0a0b1261982 842 Gene3D G3DSA:3.40.228.10 166 278 4.5E-41 T 26-04-2017 A4V04_RS07975 900eeeceb3f61862f043e0a0b1261982 842 Gene3D G3DSA:3.40.228.10 328 429 4.5E-41 T 26-04-2017 A4V04_RS07975 900eeeceb3f61862f043e0a0b1261982 842 Gene3D G3DSA:2.40.40.20 701 841 9.4E-14 T 26-04-2017 A4V04_RS07975 900eeeceb3f61862f043e0a0b1261982 842 Gene3D G3DSA:2.20.25.90 31 94 9.9E-7 T 26-04-2017 A4V04_RS07975 900eeeceb3f61862f043e0a0b1261982 842 Gene3D G3DSA:3.40.50.740 430 678 3.0E-46 T 26-04-2017 A4V04_RS07975 900eeeceb3f61862f043e0a0b1261982 842 Gene3D G3DSA:3.40.50.740 95 165 3.0E-46 T 26-04-2017 A4V04_RS07975 900eeeceb3f61862f043e0a0b1261982 842 Pfam PF00384 Molybdopterin oxidoreductase 93 588 8.1E-41 T 26-04-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS04195 6012ecd9047a431cdcbd32228206bf56 673 Pfam PF03050 Transposase IS66 family 258 585 5.3E-29 T 26-04-2017 IPR004291 Transposase, IS66 A4V04_RS11400 206d2899385ef76dd074a8d8181a1207 325 Gene3D G3DSA:3.40.190.10 180 264 2.1E-5 T 26-04-2017 A4V04_RS11400 206d2899385ef76dd074a8d8181a1207 325 Gene3D G3DSA:1.10.10.10 7 81 1.5E-10 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS11400 206d2899385ef76dd074a8d8181a1207 325 Gene3D G3DSA:3.40.190.10 96 179 1.2E-10 T 26-04-2017 A4V04_RS11400 206d2899385ef76dd074a8d8181a1207 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 64 1.0E-7 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS11400 206d2899385ef76dd074a8d8181a1207 325 SUPERFAMILY SSF53850 95 297 1.66E-22 T 26-04-2017 A4V04_RS11400 206d2899385ef76dd074a8d8181a1207 325 SUPERFAMILY SSF46785 6 82 1.47E-10 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS11400 206d2899385ef76dd074a8d8181a1207 325 Pfam PF03466 LysR substrate binding domain 95 294 2.0E-18 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS12200 37fd792ee6a6777fda3d5248e5bac65f 366 SUPERFAMILY SSF51556 23 359 7.54E-62 T 26-04-2017 IPR032466 Metal-dependent hydrolase A4V04_RS12200 37fd792ee6a6777fda3d5248e5bac65f 366 Gene3D G3DSA:3.20.20.140 25 351 2.0E-70 T 26-04-2017 A4V04_RS12200 37fd792ee6a6777fda3d5248e5bac65f 366 Pfam PF00962 Adenosine/AMP deaminase 29 347 1.3E-39 T 26-04-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 A4V04_RS07560 9463b0413853d4ba256337d34b9b869d 343 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 162 6.8E-15 T 26-04-2017 IPR016188 PurM-like, N-terminal domain A4V04_RS07560 9463b0413853d4ba256337d34b9b869d 343 Pfam PF02769 AIR synthase related protein, C-terminal domain 175 336 9.3E-38 T 26-04-2017 IPR010918 AIR synthase-related protein, C-terminal domain A4V04_RS07560 9463b0413853d4ba256337d34b9b869d 343 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 5 342 46.039 T 26-04-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4V04_RS07560 9463b0413853d4ba256337d34b9b869d 343 Gene3D G3DSA:3.90.650.10 170 337 1.4E-69 T 26-04-2017 IPR010918 AIR synthase-related protein, C-terminal domain A4V04_RS07560 9463b0413853d4ba256337d34b9b869d 343 SUPERFAMILY SSF56042 169 336 1.94E-61 T 26-04-2017 IPR010918 AIR synthase-related protein, C-terminal domain A4V04_RS07560 9463b0413853d4ba256337d34b9b869d 343 SUPERFAMILY SSF55326 5 168 3.74E-49 T 26-04-2017 A4V04_RS07560 9463b0413853d4ba256337d34b9b869d 343 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 5 332 1.4E-137 T 26-04-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4V04_RS07560 9463b0413853d4ba256337d34b9b869d 343 Gene3D G3DSA:3.30.1330.10 20 168 1.8E-59 T 26-04-2017 IPR016188 PurM-like, N-terminal domain A4V04_RS05265 38cd5d5a927bdb93be18ee7915155bb0 311 SUPERFAMILY SSF53850 41 303 2.54E-26 T 26-04-2017 A4V04_RS05265 38cd5d5a927bdb93be18ee7915155bb0 311 Pfam PF09084 NMT1/THI5 like 67 245 4.4E-6 T 26-04-2017 IPR015168 SsuA/THI5-like A4V04_RS05265 38cd5d5a927bdb93be18ee7915155bb0 311 Gene3D G3DSA:3.40.190.10 131 234 3.3E-8 T 26-04-2017 A4V04_RS12040 d7d2de8dc6c9ec36ee50433244357d03 460 Pfam PF02875 Mur ligase family, glutamate ligase domain 301 386 2.3E-18 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS12040 d7d2de8dc6c9ec36ee50433244357d03 460 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 2 451 29.448 T 26-04-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A4V04_RS12040 d7d2de8dc6c9ec36ee50433244357d03 460 Gene3D G3DSA:3.40.1390.10 2 65 7.3E-10 T 26-04-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4V04_RS12040 d7d2de8dc6c9ec36ee50433244357d03 460 Pfam PF08245 Mur ligase middle domain 77 280 2.2E-53 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS12040 d7d2de8dc6c9ec36ee50433244357d03 460 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 75 98 - T 26-04-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 A4V04_RS12040 d7d2de8dc6c9ec36ee50433244357d03 460 Gene3D G3DSA:3.40.1190.10 68 303 6.4E-78 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS12040 d7d2de8dc6c9ec36ee50433244357d03 460 Gene3D G3DSA:3.90.190.20 304 444 2.3E-49 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS12040 d7d2de8dc6c9ec36ee50433244357d03 460 SUPERFAMILY SSF63418 2 67 9.68E-12 T 26-04-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4V04_RS12040 d7d2de8dc6c9ec36ee50433244357d03 460 Pfam PF01225 Mur ligase family, catalytic domain 2 63 1.3E-5 T 26-04-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4V04_RS12040 d7d2de8dc6c9ec36ee50433244357d03 460 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 2 451 4.9E-142 T 26-04-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A4V04_RS12040 d7d2de8dc6c9ec36ee50433244357d03 460 SUPERFAMILY SSF53244 302 453 2.75E-42 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS12040 d7d2de8dc6c9ec36ee50433244357d03 460 SUPERFAMILY SSF53623 68 296 3.14E-74 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS11045 4c871b1ce82ff60ec863932285b39c6b 237 Pfam PF02665 Nitrate reductase gamma subunit 10 230 3.1E-66 T 26-04-2017 IPR023234 NarG-like domain A4V04_RS11045 4c871b1ce82ff60ec863932285b39c6b 237 SUPERFAMILY SSF103501 8 230 8.37E-51 T 26-04-2017 IPR023234 NarG-like domain A4V04_RS11045 4c871b1ce82ff60ec863932285b39c6b 237 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 8 230 7.6E-50 T 26-04-2017 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 A4V04_RS11045 4c871b1ce82ff60ec863932285b39c6b 237 Gene3D G3DSA:1.20.950.20 8 221 2.8E-52 T 26-04-2017 A4V04_RS04685 9551a6d95745ee84efef5fb92fa2720a 375 Pfam PF12698 ABC-2 family transporter protein 28 363 6.7E-46 T 26-04-2017 A4V04_RS04685 9551a6d95745ee84efef5fb92fa2720a 375 Gene3D G3DSA:3.40.1710.10 55 143 1.9E-4 T 26-04-2017 A4V04_RS09365 9bdb401b87c0fe99986e1bc5a0198ed9 365 Gene3D G3DSA:2.40.160.10 22 363 5.2E-54 T 26-04-2017 IPR023614 Porin domain A4V04_RS09365 9bdb401b87c0fe99986e1bc5a0198ed9 365 Pfam PF13609 Gram-negative porin 13 340 2.0E-35 T 26-04-2017 A4V04_RS09365 9bdb401b87c0fe99986e1bc5a0198ed9 365 PRINTS PR00183 E.coli/Salmonella-type porin signature 241 258 7.0E-7 T 26-04-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 A4V04_RS09365 9bdb401b87c0fe99986e1bc5a0198ed9 365 PRINTS PR00183 E.coli/Salmonella-type porin signature 160 182 7.0E-7 T 26-04-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 A4V04_RS09365 9bdb401b87c0fe99986e1bc5a0198ed9 365 PRINTS PR00183 E.coli/Salmonella-type porin signature 268 287 7.0E-7 T 26-04-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 A4V04_RS09365 9bdb401b87c0fe99986e1bc5a0198ed9 365 PRINTS PR00183 E.coli/Salmonella-type porin signature 54 72 7.0E-7 T 26-04-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 A4V04_RS09365 9bdb401b87c0fe99986e1bc5a0198ed9 365 PRINTS PR00183 E.coli/Salmonella-type porin signature 102 124 7.0E-7 T 26-04-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 A4V04_RS09365 9bdb401b87c0fe99986e1bc5a0198ed9 365 SUPERFAMILY SSF56935 23 365 3.66E-48 T 26-04-2017 A4V04_RS03320 31ccd3c122ea30a1b932ff1f9328f358 676 Gene3D G3DSA:3.20.70.20 133 661 8.5E-202 T 26-04-2017 A4V04_RS03320 31ccd3c122ea30a1b932ff1f9328f358 676 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 128 659 1.1E-175 T 26-04-2017 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 A4V04_RS03320 31ccd3c122ea30a1b932ff1f9328f358 676 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 127 661 8.7E-143 T 26-04-2017 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 A4V04_RS03320 31ccd3c122ea30a1b932ff1f9328f358 676 SUPERFAMILY SSF51998 128 661 2.29E-158 T 26-04-2017 A4V04_RS03320 31ccd3c122ea30a1b932ff1f9328f358 676 Pfam PF03477 ATP cone domain 10 98 1.3E-20 T 26-04-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A4V04_RS07780 68fe8463e87302cb21d9fe5c49163e41 330 PIRSF PIRSF000904 1 330 3.2E-117 T 26-04-2017 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A4V04_RS07780 68fe8463e87302cb21d9fe5c49163e41 330 Gene3D G3DSA:3.40.190.80 192 329 3.3E-56 T 26-04-2017 A4V04_RS07780 68fe8463e87302cb21d9fe5c49163e41 330 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 3 329 44.889 T 26-04-2017 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A4V04_RS07780 68fe8463e87302cb21d9fe5c49163e41 330 Gene3D G3DSA:3.30.540.10 3 191 5.8E-66 T 26-04-2017 A4V04_RS07780 68fe8463e87302cb21d9fe5c49163e41 330 PIRSF PIRSF500210 1 330 5.2E-121 T 26-04-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A4V04_RS07780 68fe8463e87302cb21d9fe5c49163e41 330 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 5 190 7.6E-53 T 26-04-2017 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A4V04_RS07780 68fe8463e87302cb21d9fe5c49163e41 330 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 175 198 1.9E-62 T 26-04-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A4V04_RS07780 68fe8463e87302cb21d9fe5c49163e41 330 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 144 167 1.9E-62 T 26-04-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A4V04_RS07780 68fe8463e87302cb21d9fe5c49163e41 330 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 27 54 1.9E-62 T 26-04-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A4V04_RS07780 68fe8463e87302cb21d9fe5c49163e41 330 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 303 328 1.9E-62 T 26-04-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A4V04_RS07780 68fe8463e87302cb21d9fe5c49163e41 330 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 201 228 1.9E-62 T 26-04-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A4V04_RS07780 68fe8463e87302cb21d9fe5c49163e41 330 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 64 90 1.9E-62 T 26-04-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A4V04_RS07780 68fe8463e87302cb21d9fe5c49163e41 330 SUPERFAMILY SSF56655 3 328 2.4E-108 T 26-04-2017 A4V04_RS03265 eadd7e7ac46f15f88fe91785006f4781 623 Pfam PF01609 Transposase DDE domain 208 535 4.6E-13 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS03265 eadd7e7ac46f15f88fe91785006f4781 623 SUPERFAMILY SSF53098 479 548 4.85E-9 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS07110 eadd7e7ac46f15f88fe91785006f4781 623 Pfam PF01609 Transposase DDE domain 208 535 4.6E-13 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS07110 eadd7e7ac46f15f88fe91785006f4781 623 SUPERFAMILY SSF53098 479 548 4.85E-9 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS06240 eadd7e7ac46f15f88fe91785006f4781 623 Pfam PF01609 Transposase DDE domain 208 535 4.6E-13 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS06240 eadd7e7ac46f15f88fe91785006f4781 623 SUPERFAMILY SSF53098 479 548 4.85E-9 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS06070 eadd7e7ac46f15f88fe91785006f4781 623 Pfam PF01609 Transposase DDE domain 208 535 4.6E-13 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS06070 eadd7e7ac46f15f88fe91785006f4781 623 SUPERFAMILY SSF53098 479 548 4.85E-9 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS10875 eadd7e7ac46f15f88fe91785006f4781 623 Pfam PF01609 Transposase DDE domain 208 535 4.6E-13 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS10875 eadd7e7ac46f15f88fe91785006f4781 623 SUPERFAMILY SSF53098 479 548 4.85E-9 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS02115 b11f1e4204bda3ae444cc10652a6635c 469 Gene3D G3DSA:3.40.50.300 1 393 6.5E-19 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02115 b11f1e4204bda3ae444cc10652a6635c 469 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 46 368 6.6E-27 T 26-04-2017 IPR003959 ATPase, AAA-type, core GO:0005524 A4V04_RS02115 b11f1e4204bda3ae444cc10652a6635c 469 SUPERFAMILY SSF52540 283 369 1.7E-10 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02115 b11f1e4204bda3ae444cc10652a6635c 469 SUPERFAMILY SSF52540 1 211 1.7E-10 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06080 57f49dc1ac6eb7d4107185ebbfadbf13 456 Pfam PF01609 Transposase DDE domain 125 372 3.9E-10 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS00905 4467ced90f2c4b9c01864be76dc3d0a0 321 Gene3D G3DSA:3.90.1640.10 21 204 1.5E-50 T 26-04-2017 A4V04_RS00905 4467ced90f2c4b9c01864be76dc3d0a0 321 SUPERFAMILY SSF64182 22 319 3.14E-60 T 26-04-2017 A4V04_RS00905 4467ced90f2c4b9c01864be76dc3d0a0 321 Pfam PF02833 DHHA2 domain 199 318 1.2E-17 T 26-04-2017 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1 A4V04_RS00905 4467ced90f2c4b9c01864be76dc3d0a0 321 SMART SM01131 198 320 2.5E-38 T 26-04-2017 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1 A4V04_RS00905 4467ced90f2c4b9c01864be76dc3d0a0 321 Pfam PF01368 DHH family 22 162 9.6E-16 T 26-04-2017 IPR001667 DDH domain A4V04_RS09225 5b08b287f987f6f5026d4343e6f4891f 207 Gene3D G3DSA:1.10.10.10 151 198 8.9E-20 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09225 5b08b287f987f6f5026d4343e6f4891f 207 SUPERFAMILY SSF46894 136 201 1.84E-18 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS09225 5b08b287f987f6f5026d4343e6f4891f 207 SMART SM00448 10 121 6.8E-22 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS09225 5b08b287f987f6f5026d4343e6f4891f 207 Gene3D G3DSA:3.40.50.2300 12 150 5.9E-29 T 26-04-2017 A4V04_RS09225 5b08b287f987f6f5026d4343e6f4891f 207 SMART SM00421 145 202 1.6E-18 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS09225 5b08b287f987f6f5026d4343e6f4891f 207 SUPERFAMILY SSF52172 14 148 6.83E-29 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS09225 5b08b287f987f6f5026d4343e6f4891f 207 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS09225 5b08b287f987f6f5026d4343e6f4891f 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 198 1.2E-17 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS09225 5b08b287f987f6f5026d4343e6f4891f 207 Pfam PF00072 Response regulator receiver domain 12 122 2.8E-22 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS09225 5b08b287f987f6f5026d4343e6f4891f 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 8.0E-13 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS09225 5b08b287f987f6f5026d4343e6f4891f 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 8.0E-13 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS09225 5b08b287f987f6f5026d4343e6f4891f 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 8.0E-13 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS09165 cea65906d7ae71fe67060d838ee49790 414 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 106 414 3.4E-22 T 26-04-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 A4V04_RS09165 cea65906d7ae71fe67060d838ee49790 414 Gene3D G3DSA:2.40.128.130 127 414 2.9E-27 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS09165 cea65906d7ae71fe67060d838ee49790 414 SMART SM00869 146 404 2.3E-22 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS09165 cea65906d7ae71fe67060d838ee49790 414 Pfam PF03797 Autotransporter beta-domain 149 393 1.8E-25 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS09165 cea65906d7ae71fe67060d838ee49790 414 SUPERFAMILY SSF103515 115 414 2.22E-28 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS08415 c4f90b0c3b2c7c4e9c6ba532a82a13fd 250 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 10 233 34.854 T 26-04-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4V04_RS08415 c4f90b0c3b2c7c4e9c6ba532a82a13fd 250 Gene3D G3DSA:3.40.470.10 7 232 2.0E-78 T 26-04-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4V04_RS08415 c4f90b0c3b2c7c4e9c6ba532a82a13fd 250 SUPERFAMILY SSF52141 9 233 1.46E-72 T 26-04-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4V04_RS08415 c4f90b0c3b2c7c4e9c6ba532a82a13fd 250 Pfam PF03167 Uracil DNA glycosylase superfamily 61 221 4.9E-22 T 26-04-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4V04_RS08415 c4f90b0c3b2c7c4e9c6ba532a82a13fd 250 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 63 72 - T 26-04-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4V04_RS08415 c4f90b0c3b2c7c4e9c6ba532a82a13fd 250 SMART SM00986 55 222 2.4E-29 T 26-04-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4V04_RS08415 c4f90b0c3b2c7c4e9c6ba532a82a13fd 250 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 12 226 1.3E-65 T 26-04-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4V04_RS08415 c4f90b0c3b2c7c4e9c6ba532a82a13fd 250 SMART SM00987 55 222 2.4E-29 T 26-04-2017 A4V04_RS07935 a8fcc27f4fa5a3a8ecf9b6282fd6df0f 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS07935 a8fcc27f4fa5a3a8ecf9b6282fd6df0f 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.7E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS07935 a8fcc27f4fa5a3a8ecf9b6282fd6df0f 441 SUPERFAMILY SSF56672 7 374 4.67E-51 T 26-04-2017 A4V04_RS07935 a8fcc27f4fa5a3a8ecf9b6282fd6df0f 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 1.8E-119 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS00865 2e0148fbfb1b230852bda051ef1005cb 338 Gene3D G3DSA:3.30.420.40 1 159 2.5E-47 T 26-04-2017 A4V04_RS00865 2e0148fbfb1b230852bda051ef1005cb 338 Gene3D G3DSA:3.30.420.40 233 324 8.9E-4 T 26-04-2017 A4V04_RS00865 2e0148fbfb1b230852bda051ef1005cb 338 SUPERFAMILY SSF53067 101 310 8.33E-43 T 26-04-2017 A4V04_RS00865 2e0148fbfb1b230852bda051ef1005cb 338 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 334 61.588 T 26-04-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4V04_RS00865 2e0148fbfb1b230852bda051ef1005cb 338 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 315 1.4E-130 T 26-04-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4V04_RS00865 2e0148fbfb1b230852bda051ef1005cb 338 SUPERFAMILY SSF53067 2 121 6.34E-30 T 26-04-2017 A4V04_RS00865 2e0148fbfb1b230852bda051ef1005cb 338 Pfam PF00814 Glycoprotease family 25 308 6.6E-99 T 26-04-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4V04_RS00865 2e0148fbfb1b230852bda051ef1005cb 338 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 308 2.0E-110 T 26-04-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4V04_RS00865 2e0148fbfb1b230852bda051ef1005cb 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 265 274 9.3E-48 T 26-04-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4V04_RS00865 2e0148fbfb1b230852bda051ef1005cb 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 9.3E-48 T 26-04-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4V04_RS00865 2e0148fbfb1b230852bda051ef1005cb 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 9.3E-48 T 26-04-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4V04_RS00865 2e0148fbfb1b230852bda051ef1005cb 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 9.3E-48 T 26-04-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4V04_RS00865 2e0148fbfb1b230852bda051ef1005cb 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 9.3E-48 T 26-04-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4V04_RS00865 2e0148fbfb1b230852bda051ef1005cb 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 9.3E-48 T 26-04-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 Pfam PF02096 60Kd inner membrane protein 377 555 3.8E-60 T 26-04-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 6 375 2.1E-96 T 26-04-2017 IPR028053 Membrane insertase YidC, N-terminal A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 376 555 8.7E-69 T 26-04-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 Pfam PF14849 YidC periplasmic domain 78 366 1.4E-73 T 26-04-2017 IPR028053 Membrane insertase YidC, N-terminal A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 6 557 23.82 T 26-04-2017 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 PRINTS PR00701 60kDa inner membrane protein signature 347 367 3.9E-65 T 26-04-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 PRINTS PR00701 60kDa inner membrane protein signature 485 507 3.9E-65 T 26-04-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 PRINTS PR00701 60kDa inner membrane protein signature 521 544 3.9E-65 T 26-04-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 PRINTS PR00701 60kDa inner membrane protein signature 4 25 3.9E-65 T 26-04-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 PRINTS PR00701 60kDa inner membrane protein signature 274 289 3.9E-65 T 26-04-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 PRINTS PR00701 60kDa inner membrane protein signature 185 205 3.9E-65 T 26-04-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 PRINTS PR00701 60kDa inner membrane protein signature 438 461 3.9E-65 T 26-04-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 PRINTS PR00701 60kDa inner membrane protein signature 239 257 3.9E-65 T 26-04-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 PRINTS PR01900 YidC translocation/secretion protein signature 362 378 6.5E-21 T 26-04-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 PRINTS PR01900 YidC translocation/secretion protein signature 491 506 6.5E-21 T 26-04-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A4V04_RS10500 ef1ea95894255e06345b24701f0ad3c8 567 PRINTS PR01900 YidC translocation/secretion protein signature 510 534 6.5E-21 T 26-04-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 9 93 5.3E-23 T 26-04-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 SMART SM01016 7 93 1.6E-28 T 26-04-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 Pfam PF05746 DALR anticodon binding domain 447 570 8.6E-38 T 26-04-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 Gene3D G3DSA:3.40.50.620 117 451 2.7E-101 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 122 137 8.4E-22 T 26-04-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 310 331 8.4E-22 T 26-04-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 137 153 8.4E-22 T 26-04-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 161 174 8.4E-22 T 26-04-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 Pfam PF00750 tRNA synthetases class I (R) 105 412 1.5E-22 T 26-04-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 Hamap MF_00123 Arginine--tRNA ligase [argS]. 7 570 25.013 T 26-04-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 Gene3D G3DSA:3.30.1360.70 5 111 2.2E-28 T 26-04-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 SUPERFAMILY SSF55190 5 113 2.62E-21 T 26-04-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 Gene3D G3DSA:1.10.730.10 452 570 2.5E-45 T 26-04-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 7 570 8.0E-127 T 26-04-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 SUPERFAMILY SSF52374 118 457 8.85E-81 T 26-04-2017 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 SUPERFAMILY SSF47323 442 570 3.4E-37 T 26-04-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 141 - T 26-04-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS11070 a9a0f7fa98364abb85fb76d6171bfecb 577 SMART SM00836 447 570 7.5E-58 T 26-04-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A4V04_RS03645 8b47c75e10b63001923f43b02b9a01b2 301 Gene3D G3DSA:3.40.50.300 76 234 3.6E-36 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03645 8b47c75e10b63001923f43b02b9a01b2 301 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 40 293 3.1E-63 T 26-04-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 A4V04_RS03645 8b47c75e10b63001923f43b02b9a01b2 301 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 7 299 30.625 T 26-04-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 A4V04_RS03645 8b47c75e10b63001923f43b02b9a01b2 301 SUPERFAMILY SSF52540 77 294 8.3E-42 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03645 8b47c75e10b63001923f43b02b9a01b2 301 Pfam PF03193 Protein of unknown function, DUF258 61 234 3.2E-43 T 26-04-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 A4V04_RS03645 8b47c75e10b63001923f43b02b9a01b2 301 Gene3D G3DSA:2.40.50.140 10 62 2.6E-5 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS03645 8b47c75e10b63001923f43b02b9a01b2 301 Gene3D G3DSA:1.10.40.50 236 295 1.9E-21 T 26-04-2017 A4V04_RS11520 6f2101e74c8e29b3387ecf6887494c02 374 Pfam PF06114 Domain of unknown function (DUF955) 180 290 1.5E-14 T 26-04-2017 IPR010359 HTH domain, IrrE-type A4V04_RS02865 7aeb6b502aca251e000686c9bd08f3e4 685 Pfam PF03050 Transposase IS66 family 283 597 5.6E-29 T 26-04-2017 IPR004291 Transposase, IS66 A4V04_RS12600 97930a799d9f8a2383d998df5f043440 211 SUPERFAMILY SSF52317 3 209 3.91E-49 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS12600 97930a799d9f8a2383d998df5f043440 211 Pfam PF00117 Glutamine amidotransferase class-I 5 197 4.2E-14 T 26-04-2017 IPR017926 Glutamine amidotransferase A4V04_RS12600 97930a799d9f8a2383d998df5f043440 211 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 2 209 33.113 T 26-04-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A4V04_RS12600 97930a799d9f8a2383d998df5f043440 211 Gene3D G3DSA:3.40.50.880 1 209 2.8E-71 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS12600 97930a799d9f8a2383d998df5f043440 211 PIRSF PIRSF000495 1 211 2.4E-63 T 26-04-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A4V04_RS12600 97930a799d9f8a2383d998df5f043440 211 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 3 208 4.7E-59 T 26-04-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A4V04_RS12305 e3c826f0d9d8e58c8ac5bb5f380948a7 366 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 2 366 38.085 T 26-04-2017 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 A4V04_RS12305 e3c826f0d9d8e58c8ac5bb5f380948a7 366 SUPERFAMILY SSF53067 65 110 2.18E-23 T 26-04-2017 A4V04_RS12305 e3c826f0d9d8e58c8ac5bb5f380948a7 366 SUPERFAMILY SSF53067 140 320 2.18E-23 T 26-04-2017 A4V04_RS12305 e3c826f0d9d8e58c8ac5bb5f380948a7 366 SUPERFAMILY SSF53067 3 34 2.18E-23 T 26-04-2017 A4V04_RS12305 e3c826f0d9d8e58c8ac5bb5f380948a7 366 Pfam PF03702 Uncharacterised protein family (UPF0075) 3 365 1.2E-128 T 26-04-2017 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 A4V04_RS12305 e3c826f0d9d8e58c8ac5bb5f380948a7 366 Gene3D G3DSA:3.30.420.40 3 195 6.1E-65 T 26-04-2017 A4V04_RS13095 961810a0fcb2db564c632fbd1494fbc9 231 Pfam PF00005 ABC transporter 25 158 2.1E-28 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS13095 961810a0fcb2db564c632fbd1494fbc9 231 Gene3D G3DSA:3.40.50.300 25 222 8.9E-48 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13095 961810a0fcb2db564c632fbd1494fbc9 231 SUPERFAMILY SSF52540 8 224 3.1E-50 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13095 961810a0fcb2db564c632fbd1494fbc9 231 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS13095 961810a0fcb2db564c632fbd1494fbc9 231 SMART SM00382 22 222 5.9E-8 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS01960 501814356882bb00eb1f3854140c4ae5 367 Pfam PF03275 UDP-galactopyranose mutase 149 348 7.3E-74 T 26-04-2017 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 A4V04_RS01960 501814356882bb00eb1f3854140c4ae5 367 SUPERFAMILY SSF51971 1 264 1.13E-44 T 26-04-2017 A4V04_RS01960 501814356882bb00eb1f3854140c4ae5 367 SUPERFAMILY SSF51971 333 365 1.13E-44 T 26-04-2017 A4V04_RS01960 501814356882bb00eb1f3854140c4ae5 367 Gene3D G3DSA:3.40.50.720 323 364 1.8E-36 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01960 501814356882bb00eb1f3854140c4ae5 367 Gene3D G3DSA:3.40.50.720 184 256 1.8E-36 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01960 501814356882bb00eb1f3854140c4ae5 367 Gene3D G3DSA:3.40.50.720 4 78 1.8E-36 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01960 501814356882bb00eb1f3854140c4ae5 367 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 72 1.5E-13 T 26-04-2017 A4V04_RS01960 501814356882bb00eb1f3854140c4ae5 367 SUPERFAMILY SSF54373 247 315 5.3E-18 T 26-04-2017 A4V04_RS01960 501814356882bb00eb1f3854140c4ae5 367 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 2 364 2.3E-132 T 26-04-2017 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 A4V04_RS11605 b6860c7e895e256fe31ef1530622ad02 135 SUPERFAMILY SSF54637 6 132 1.16E-40 T 26-04-2017 IPR029069 HotDog domain A4V04_RS11605 b6860c7e895e256fe31ef1530622ad02 135 Pfam PF03061 Thioesterase superfamily 22 105 4.1E-19 T 26-04-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 A4V04_RS11605 b6860c7e895e256fe31ef1530622ad02 135 Gene3D G3DSA:3.10.129.10 6 133 1.1E-45 T 26-04-2017 IPR029069 HotDog domain A4V04_RS11605 b6860c7e895e256fe31ef1530622ad02 135 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 6 130 2.7E-49 T 26-04-2017 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 A4V04_RS11605 b6860c7e895e256fe31ef1530622ad02 135 PIRSF PIRSF003230 1 135 7.7E-45 T 26-04-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A4V04_RS11605 b6860c7e895e256fe31ef1530622ad02 135 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 10 121 7.0E-33 T 26-04-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A4V04_RS10390 29ce82823880409a3d9e501746bfa48e 267 Pfam PF03099 Biotin/lipoate A/B protein ligase family 27 148 2.7E-12 T 26-04-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 A4V04_RS10390 29ce82823880409a3d9e501746bfa48e 267 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 23 258 1.8E-42 T 26-04-2017 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4V04_RS10390 29ce82823880409a3d9e501746bfa48e 267 Pfam PF02237 Biotin protein ligase C terminal domain 221 259 3.6E-5 T 26-04-2017 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4V04_RS10390 29ce82823880409a3d9e501746bfa48e 267 Gene3D G3DSA:3.30.930.10 16 210 3.3E-41 T 26-04-2017 A4V04_RS10390 29ce82823880409a3d9e501746bfa48e 267 SUPERFAMILY SSF55681 17 211 5.3E-36 T 26-04-2017 A4V04_RS10390 29ce82823880409a3d9e501746bfa48e 267 Gene3D G3DSA:2.30.30.100 224 257 2.1E-5 T 26-04-2017 A4V04_RS09670 d1b318f3ed6000be3514a594a658f661 193 SUPERFAMILY SSF52218 4 192 8.56E-36 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS09670 d1b318f3ed6000be3514a594a658f661 193 Gene3D G3DSA:3.40.50.360 4 192 5.5E-37 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS09670 d1b318f3ed6000be3514a594a658f661 193 Pfam PF02525 Flavodoxin-like fold 52 188 1.3E-29 T 26-04-2017 IPR003680 Flavodoxin-like fold A4V04_RS08640 d868af447efd11ee83a69e772b7231be 274 Pfam PF00398 Ribosomal RNA adenine dimethylase 8 258 4.6E-55 T 26-04-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A4V04_RS08640 d868af447efd11ee83a69e772b7231be 274 SUPERFAMILY SSF53335 8 260 7.8E-70 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS08640 d868af447efd11ee83a69e772b7231be 274 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 40 67 - T 26-04-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A4V04_RS08640 d868af447efd11ee83a69e772b7231be 274 Gene3D G3DSA:3.40.50.150 5 195 4.0E-62 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS08640 d868af447efd11ee83a69e772b7231be 274 SMART SM00650 24 194 1.9E-70 T 26-04-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A4V04_RS08640 d868af447efd11ee83a69e772b7231be 274 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 8 259 52.712 T 26-04-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A4V04_RS08640 d868af447efd11ee83a69e772b7231be 274 Gene3D G3DSA:1.10.8.100 198 259 2.0E-21 T 26-04-2017 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 A4V04_RS08640 d868af447efd11ee83a69e772b7231be 274 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 9 257 1.1E-77 T 26-04-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A4V04_RS01885 3ec6c97f97e21b9f84f7ad2fd6f4d384 329 Pfam PF07728 AAA domain (dynein-related subfamily) 57 175 6.0E-16 T 26-04-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A4V04_RS01885 3ec6c97f97e21b9f84f7ad2fd6f4d384 329 SUPERFAMILY SSF52540 24 244 2.21E-26 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01885 3ec6c97f97e21b9f84f7ad2fd6f4d384 329 SUPERFAMILY SSF52540 281 301 2.21E-26 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01885 3ec6c97f97e21b9f84f7ad2fd6f4d384 329 Gene3D G3DSA:3.40.50.300 26 223 1.4E-23 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02280 20aec2aec77efb5bd6b85bb8dbc045d9 482 SMART SM00998 395 473 7.4E-13 T 26-04-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS02280 20aec2aec77efb5bd6b85bb8dbc045d9 482 Gene3D G3DSA:1.20.200.10 138 399 2.1E-68 T 26-04-2017 A4V04_RS02280 20aec2aec77efb5bd6b85bb8dbc045d9 482 Pfam PF10397 Adenylosuccinate lyase C-terminus 397 472 3.6E-12 T 26-04-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS02280 20aec2aec77efb5bd6b85bb8dbc045d9 482 SUPERFAMILY SSF48557 44 475 1.73E-99 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS02280 20aec2aec77efb5bd6b85bb8dbc045d9 482 Pfam PF00206 Lyase 52 327 2.6E-44 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS02280 20aec2aec77efb5bd6b85bb8dbc045d9 482 PRINTS PR00145 Argininosuccinate lyase family signature 307 323 1.3E-5 T 26-04-2017 A4V04_RS02280 20aec2aec77efb5bd6b85bb8dbc045d9 482 PRINTS PR00145 Argininosuccinate lyase family signature 265 289 1.3E-5 T 26-04-2017 A4V04_RS02280 20aec2aec77efb5bd6b85bb8dbc045d9 482 PRINTS PR00145 Argininosuccinate lyase family signature 175 195 1.3E-5 T 26-04-2017 A4V04_RS02280 20aec2aec77efb5bd6b85bb8dbc045d9 482 Gene3D G3DSA:1.10.40.30 400 473 2.1E-17 T 26-04-2017 A4V04_RS02280 20aec2aec77efb5bd6b85bb8dbc045d9 482 Gene3D G3DSA:1.10.275.10 39 137 1.1E-30 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS02280 20aec2aec77efb5bd6b85bb8dbc045d9 482 PRINTS PR00149 Fumarate lyase superfamily signature 180 198 5.2E-21 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS02280 20aec2aec77efb5bd6b85bb8dbc045d9 482 PRINTS PR00149 Fumarate lyase superfamily signature 265 292 5.2E-21 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS02280 20aec2aec77efb5bd6b85bb8dbc045d9 482 PRINTS PR00149 Fumarate lyase superfamily signature 307 323 5.2E-21 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS02280 20aec2aec77efb5bd6b85bb8dbc045d9 482 PRINTS PR00149 Fumarate lyase superfamily signature 135 153 5.2E-21 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS10700 f585f2e66f38c0537210f2f7512b9da5 434 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 5 434 2.0E-129 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS10700 f585f2e66f38c0537210f2f7512b9da5 434 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 5 361 1.5E-126 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS10700 f585f2e66f38c0537210f2f7512b9da5 434 PIRSF PIRSF004539 1 434 7.0E-136 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS05310 af86428c823f67961cccac3c735abe36 356 PIRSF PIRSF001456 3 356 2.8E-134 T 26-04-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4V04_RS05310 af86428c823f67961cccac3c735abe36 356 TIGRFAM TIGR00033 aroC: chorismate synthase 12 353 1.9E-132 T 26-04-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4V04_RS05310 af86428c823f67961cccac3c735abe36 356 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 26-04-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4V04_RS05310 af86428c823f67961cccac3c735abe36 356 Gene3D G3DSA:3.60.150.10 10 354 7.2E-145 T 26-04-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4V04_RS05310 af86428c823f67961cccac3c735abe36 356 Pfam PF01264 Chorismate synthase 11 348 2.5E-130 T 26-04-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4V04_RS05310 af86428c823f67961cccac3c735abe36 356 ProSitePatterns PS00789 Chorismate synthase signature 3. 322 338 - T 26-04-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4V04_RS05310 af86428c823f67961cccac3c735abe36 356 Hamap MF_00300 Chorismate synthase [aroC]. 10 355 35.182 T 26-04-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4V04_RS05310 af86428c823f67961cccac3c735abe36 356 SUPERFAMILY SSF103263 4 353 5.89E-136 T 26-04-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4V04_RS05310 af86428c823f67961cccac3c735abe36 356 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 26-04-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4V04_RS05675 7e6d00ee840843a32f79fb42da0768d6 198 Gene3D G3DSA:3.90.950.10 3 193 1.1E-72 T 26-04-2017 IPR029001 Inosine triphosphate pyrophosphatase-like A4V04_RS05675 7e6d00ee840843a32f79fb42da0768d6 198 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 3 195 44.735 T 26-04-2017 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 A4V04_RS05675 7e6d00ee840843a32f79fb42da0768d6 198 SUPERFAMILY SSF52972 3 194 1.23E-66 T 26-04-2017 IPR029001 Inosine triphosphate pyrophosphatase-like A4V04_RS05675 7e6d00ee840843a32f79fb42da0768d6 198 Pfam PF01725 Ham1 family 5 191 1.2E-50 T 26-04-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 A4V04_RS05675 7e6d00ee840843a32f79fb42da0768d6 198 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 192 4.4E-55 T 26-04-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 A4V04_RS03020 5d5f244ab9c16685beb4dbc814312e12 260 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 27 257 5.8E-61 T 26-04-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase A4V04_RS03020 5d5f244ab9c16685beb4dbc814312e12 260 Gene3D G3DSA:3.60.140.10 8 258 3.3E-77 T 26-04-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase A4V04_RS03020 5d5f244ab9c16685beb4dbc814312e12 260 SUPERFAMILY SSF64438 8 258 1.37E-67 T 26-04-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic A4V04_RS03020 5d5f244ab9c16685beb4dbc814312e12 260 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 45 257 5.6E-48 T 26-04-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase A4V04_RS10650 a794a4414cc6b9295de06d9100ba5c8f 272 Gene3D G3DSA:1.20.120.220 88 272 1.4E-48 T 26-04-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4V04_RS10650 a794a4414cc6b9295de06d9100ba5c8f 272 Pfam PF00119 ATP synthase A chain 36 265 2.5E-53 T 26-04-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4V04_RS10650 a794a4414cc6b9295de06d9100ba5c8f 272 SUPERFAMILY SSF81336 86 266 9.55E-40 T 26-04-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4V04_RS10650 a794a4414cc6b9295de06d9100ba5c8f 272 PRINTS PR00123 ATP synthase A subunit signature 192 214 1.3E-11 T 26-04-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4V04_RS10650 a794a4414cc6b9295de06d9100ba5c8f 272 PRINTS PR00123 ATP synthase A subunit signature 93 109 1.3E-11 T 26-04-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4V04_RS10650 a794a4414cc6b9295de06d9100ba5c8f 272 PRINTS PR00123 ATP synthase A subunit signature 252 267 1.3E-11 T 26-04-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4V04_RS10650 a794a4414cc6b9295de06d9100ba5c8f 272 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 27 267 3.7E-39 T 26-04-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4V04_RS10650 a794a4414cc6b9295de06d9100ba5c8f 272 Hamap MF_01393 ATP synthase subunit a [atpB]. 9 272 13.937 T 26-04-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4V04_RS10650 a794a4414cc6b9295de06d9100ba5c8f 272 ProSitePatterns PS00449 ATP synthase a subunit signature. 195 204 - T 26-04-2017 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 A4V04_RS03620 b71d33b711f776ad7ddeef9621b4a5b6 245 Gene3D G3DSA:3.40.1280.10 1 159 2.2E-59 T 26-04-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4V04_RS03620 b71d33b711f776ad7ddeef9621b4a5b6 245 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 227 2.3E-81 T 26-04-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4V04_RS03620 b71d33b711f776ad7ddeef9621b4a5b6 245 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 220 3.0E-54 T 26-04-2017 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4V04_RS03620 b71d33b711f776ad7ddeef9621b4a5b6 245 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 245 95.207 T 26-04-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4V04_RS03620 b71d33b711f776ad7ddeef9621b4a5b6 245 SUPERFAMILY SSF75217 1 231 6.11E-85 T 26-04-2017 IPR029028 Alpha/beta knot methyltransferases A4V04_RS03620 b71d33b711f776ad7ddeef9621b4a5b6 245 PIRSF PIRSF000386 1 244 1.4E-82 T 26-04-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4V04_RS03620 b71d33b711f776ad7ddeef9621b4a5b6 245 Gene3D G3DSA:1.10.1270.20 163 243 2.4E-28 T 26-04-2017 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4V04_RS04075 35ca31727445ca05e002d764c43d0d98 591 PRINTS PR01183 Ribonucleotide reductase large chain signature 266 277 8.2E-13 T 26-04-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4V04_RS04075 35ca31727445ca05e002d764c43d0d98 591 PRINTS PR01183 Ribonucleotide reductase large chain signature 403 430 8.2E-13 T 26-04-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4V04_RS04075 35ca31727445ca05e002d764c43d0d98 591 PRINTS PR01183 Ribonucleotide reductase large chain signature 148 167 8.2E-13 T 26-04-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4V04_RS04075 35ca31727445ca05e002d764c43d0d98 591 PRINTS PR01183 Ribonucleotide reductase large chain signature 340 362 8.2E-13 T 26-04-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4V04_RS04075 35ca31727445ca05e002d764c43d0d98 591 SUPERFAMILY SSF48168 5 72 3.4E-6 T 26-04-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4V04_RS04075 35ca31727445ca05e002d764c43d0d98 591 SUPERFAMILY SSF51998 80 453 3.05E-123 T 26-04-2017 A4V04_RS04075 35ca31727445ca05e002d764c43d0d98 591 SUPERFAMILY SSF51998 484 555 3.05E-123 T 26-04-2017 A4V04_RS04075 35ca31727445ca05e002d764c43d0d98 591 Gene3D G3DSA:3.20.70.20 42 194 2.8E-37 T 26-04-2017 A4V04_RS04075 35ca31727445ca05e002d764c43d0d98 591 Gene3D G3DSA:3.20.70.20 510 550 2.8E-37 T 26-04-2017 A4V04_RS04075 35ca31727445ca05e002d764c43d0d98 591 Gene3D G3DSA:3.20.70.20 229 449 2.8E-37 T 26-04-2017 A4V04_RS04075 35ca31727445ca05e002d764c43d0d98 591 Pfam PF02867 Ribonucleotide reductase, barrel domain 405 550 1.6E-36 T 26-04-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4V04_RS04075 35ca31727445ca05e002d764c43d0d98 591 Pfam PF02867 Ribonucleotide reductase, barrel domain 82 395 3.8E-59 T 26-04-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4V04_RS10195 2c9c36829652d81640d5161a4d6bda0c 114 Gene3D G3DSA:1.10.1130.10 29 109 1.9E-10 T 26-04-2017 IPR012286 Tetrahaem cytochrome domain A4V04_RS10195 2c9c36829652d81640d5161a4d6bda0c 114 SUPERFAMILY SSF48695 30 110 2.79E-10 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS10195 2c9c36829652d81640d5161a4d6bda0c 114 Pfam PF14537 Cytochrome c3 30 108 3.7E-15 T 26-04-2017 A4V04_RS09185 0e4b3cf4a0f0bd36d4b20fd3d9e38ba1 315 Pfam PF03916 Polysulphide reductase, NrfD 10 311 9.0E-61 T 26-04-2017 IPR005614 NrfD family A4V04_RS04670 d2291c24161bc4a5e1b3e38c56fe9ce3 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.0E-13 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS04670 d2291c24161bc4a5e1b3e38c56fe9ce3 293 SUPERFAMILY SSF53850 90 290 1.81E-26 T 26-04-2017 A4V04_RS04670 d2291c24161bc4a5e1b3e38c56fe9ce3 293 SUPERFAMILY SSF46785 4 87 3.44E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04670 d2291c24161bc4a5e1b3e38c56fe9ce3 293 Gene3D G3DSA:3.40.190.10 95 179 7.7E-11 T 26-04-2017 A4V04_RS04670 d2291c24161bc4a5e1b3e38c56fe9ce3 293 Gene3D G3DSA:1.10.10.10 3 88 4.9E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04670 d2291c24161bc4a5e1b3e38c56fe9ce3 293 Pfam PF03466 LysR substrate binding domain 89 289 3.5E-23 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS04670 d2291c24161bc4a5e1b3e38c56fe9ce3 293 Gene3D G3DSA:3.40.190.10 180 244 6.2E-4 T 26-04-2017 A4V04_RS01210 ab51e8706951f194bc9418150bd6ff4b 157 Hamap MF_00042 Ribonuclease H [rnhA]. 5 157 30.631 T 26-04-2017 IPR022892 Ribonuclease H GO:0004523 A4V04_RS01210 ab51e8706951f194bc9418150bd6ff4b 157 SUPERFAMILY SSF53098 6 149 3.16E-52 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS01210 ab51e8706951f194bc9418150bd6ff4b 157 Pfam PF00075 RNase H 8 148 6.1E-46 T 26-04-2017 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 A4V04_RS01210 ab51e8706951f194bc9418150bd6ff4b 157 Gene3D G3DSA:3.30.420.10 7 152 4.5E-55 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS13010 c6f4345bd8e2ec4101a48d6d950b55f2 172 SUPERFAMILY SSF116734 10 158 5.72E-14 T 26-04-2017 A4V04_RS01050 0623d2139067b398656616ad5543e344 389 SUPERFAMILY SSF56059 107 304 6.54E-58 T 26-04-2017 A4V04_RS01050 0623d2139067b398656616ad5543e344 389 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 12 370 5.7E-118 T 26-04-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A4V04_RS01050 0623d2139067b398656616ad5543e344 389 SUPERFAMILY SSF52440 3 105 5.32E-23 T 26-04-2017 IPR016185 Pre-ATP-grasp domain A4V04_RS01050 0623d2139067b398656616ad5543e344 389 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 11 367 40.302 T 26-04-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A4V04_RS01050 0623d2139067b398656616ad5543e344 389 Pfam PF02222 ATP-grasp domain 117 284 4.9E-52 T 26-04-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A4V04_RS01050 0623d2139067b398656616ad5543e344 389 Gene3D G3DSA:3.30.470.20 185 379 1.4E-67 T 26-04-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4V04_RS01050 0623d2139067b398656616ad5543e344 389 Gene3D G3DSA:3.30.1490.20 122 184 2.7E-17 T 26-04-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4V04_RS01050 0623d2139067b398656616ad5543e344 389 SUPERFAMILY SSF51246 309 377 4.08E-16 T 26-04-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4V04_RS01050 0623d2139067b398656616ad5543e344 389 Gene3D G3DSA:3.40.50.20 5 115 6.4E-32 T 26-04-2017 IPR016185 Pre-ATP-grasp domain A4V04_RS05205 d60e85a8e0329a7c193dfed2180b0ca0 87 Pfam PF04023 FeoA domain 9 79 4.5E-11 T 26-04-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A4V04_RS05205 d60e85a8e0329a7c193dfed2180b0ca0 87 SUPERFAMILY SSF50037 11 79 4.12E-9 T 26-04-2017 IPR008988 Transcriptional repressor, C-terminal A4V04_RS05205 d60e85a8e0329a7c193dfed2180b0ca0 87 SMART SM00899 9 81 1.6E-6 T 26-04-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A4V04_RS04995 5b516f4f1683ac5a38d8335b002514ef 78 SUPERFAMILY SSF64307 4 77 3.79E-23 T 26-04-2017 IPR001455 TusA-like domain A4V04_RS04995 5b516f4f1683ac5a38d8335b002514ef 78 Gene3D G3DSA:3.30.110.40 4 77 9.5E-27 T 26-04-2017 IPR001455 TusA-like domain A4V04_RS04995 5b516f4f1683ac5a38d8335b002514ef 78 Pfam PF01206 Sulfurtransferase TusA 9 77 1.9E-23 T 26-04-2017 IPR001455 TusA-like domain A4V04_RS04995 5b516f4f1683ac5a38d8335b002514ef 78 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 10 34 - T 26-04-2017 IPR001455 TusA-like domain A4V04_RS03500 426bdc848b3108ff0fdc3b5e1e4ce2bc 423 PIRSF PIRSF001563 1 421 1.1E-111 T 26-04-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A4V04_RS03500 426bdc848b3108ff0fdc3b5e1e4ce2bc 423 Pfam PF08245 Mur ligase middle domain 44 259 1.6E-11 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS03500 426bdc848b3108ff0fdc3b5e1e4ce2bc 423 Gene3D G3DSA:3.40.1190.10 3 281 6.9E-89 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS03500 426bdc848b3108ff0fdc3b5e1e4ce2bc 423 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 42 65 - T 26-04-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 A4V04_RS03500 426bdc848b3108ff0fdc3b5e1e4ce2bc 423 SUPERFAMILY SSF53244 284 421 2.93E-28 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS03500 426bdc848b3108ff0fdc3b5e1e4ce2bc 423 SUPERFAMILY SSF53623 3 281 5.86E-82 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS03500 426bdc848b3108ff0fdc3b5e1e4ce2bc 423 Pfam PF02875 Mur ligase family, glutamate ligase domain 284 338 2.7E-6 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS03500 426bdc848b3108ff0fdc3b5e1e4ce2bc 423 TIGRFAM TIGR01499 folC: bifunctional protein FolC 23 416 2.8E-98 T 26-04-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A4V04_RS03500 426bdc848b3108ff0fdc3b5e1e4ce2bc 423 Gene3D G3DSA:3.90.190.20 285 419 9.4E-36 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS09855 6cb68675f9499394bff3f464cd2c97e2 308 Pfam PF03916 Polysulphide reductase, NrfD 13 304 1.3E-54 T 26-04-2017 IPR005614 NrfD family A4V04_RS09855 6cb68675f9499394bff3f464cd2c97e2 308 Gene3D G3DSA:1.20.1630.10 19 306 7.4E-10 T 26-04-2017 A4V04_RS09115 f0d973b2e24f55bc01804d4d93e5dbb5 302 Gene3D G3DSA:3.40.1010.10 29 135 1.0E-14 T 26-04-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4V04_RS09115 f0d973b2e24f55bc01804d4d93e5dbb5 302 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 29 224 3.6E-26 T 26-04-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4V04_RS09115 f0d973b2e24f55bc01804d4d93e5dbb5 302 Gene3D G3DSA:3.30.950.10 136 247 1.5E-36 T 26-04-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4V04_RS09115 f0d973b2e24f55bc01804d4d93e5dbb5 302 SUPERFAMILY SSF53790 27 246 2.88E-69 T 26-04-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4V04_RS09115 f0d973b2e24f55bc01804d4d93e5dbb5 302 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 28 247 33.093 T 26-04-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS09115 f0d973b2e24f55bc01804d4d93e5dbb5 302 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 29 296 4.6E-66 T 26-04-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS09115 f0d973b2e24f55bc01804d4d93e5dbb5 302 PIRSF PIRSF005917 17 301 6.3E-86 T 26-04-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS02505 3afea195d268031061dd50af34fb71be 136 SUPERFAMILY SSF54593 7 131 1.21E-16 T 26-04-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4V04_RS02505 3afea195d268031061dd50af34fb71be 136 Gene3D G3DSA:3.10.180.10 11 130 5.9E-20 T 26-04-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4V04_RS00210 8da1ca4644eaf96aa1ecffd60cba8f35 258 Gene3D G3DSA:3.20.20.70 35 254 3.7E-17 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS00210 8da1ca4644eaf96aa1ecffd60cba8f35 258 SUPERFAMILY SSF102114 34 231 8.24E-16 T 26-04-2017 A4V04_RS00210 8da1ca4644eaf96aa1ecffd60cba8f35 258 SMART SM00729 25 249 0.0089 T 26-04-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4V04_RS00210 8da1ca4644eaf96aa1ecffd60cba8f35 258 Pfam PF04055 Radical SAM superfamily 34 191 1.7E-11 T 26-04-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 A4V04_RS04675 a195e806db5e5e8f460016e10eff1f82 330 SUPERFAMILY SSF111369 45 132 1.44E-5 T 26-04-2017 A4V04_RS04675 a195e806db5e5e8f460016e10eff1f82 330 SUPERFAMILY SSF111369 147 295 1.96E-7 T 26-04-2017 A4V04_RS04675 a195e806db5e5e8f460016e10eff1f82 330 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 103 323 2.6E-14 T 26-04-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A4V04_RS04675 a195e806db5e5e8f460016e10eff1f82 330 Pfam PF13533 Biotin-lipoyl like 54 91 2.0E-7 T 26-04-2017 A4V04_RS04675 a195e806db5e5e8f460016e10eff1f82 330 Gene3D G3DSA:2.40.50.100 44 77 8.5E-11 T 26-04-2017 A4V04_RS04675 a195e806db5e5e8f460016e10eff1f82 330 Gene3D G3DSA:2.40.50.100 207 239 8.5E-11 T 26-04-2017 A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 Pfam PF00206 Lyase 23 317 7.6E-73 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 Hamap MF_00006 Argininosuccinate lyase [argH]. 19 470 43.286 T 26-04-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 TIGRFAM TIGR00838 argH: argininosuccinate lyase 21 471 1.8E-186 T 26-04-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 Gene3D G3DSA:1.20.200.10 124 390 1.8E-106 T 26-04-2017 A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 PRINTS PR00149 Fumarate lyase superfamily signature 248 275 1.1E-26 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 PRINTS PR00149 Fumarate lyase superfamily signature 292 308 1.1E-26 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 PRINTS PR00149 Fumarate lyase superfamily signature 164 182 1.1E-26 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 PRINTS PR00149 Fumarate lyase superfamily signature 119 137 1.1E-26 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 Gene3D G3DSA:1.10.275.10 20 123 1.4E-38 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 SUPERFAMILY SSF48557 23 474 7.07E-152 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 Gene3D G3DSA:1.10.40.30 391 448 3.3E-31 T 26-04-2017 A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 Pfam PF14698 Argininosuccinate lyase C-terminal 380 447 1.1E-25 T 26-04-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 PRINTS PR00145 Argininosuccinate lyase family signature 210 226 3.8E-66 T 26-04-2017 A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 PRINTS PR00145 Argininosuccinate lyase family signature 118 140 3.8E-66 T 26-04-2017 A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 PRINTS PR00145 Argininosuccinate lyase family signature 248 272 3.8E-66 T 26-04-2017 A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 PRINTS PR00145 Argininosuccinate lyase family signature 159 179 3.8E-66 T 26-04-2017 A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 PRINTS PR00145 Argininosuccinate lyase family signature 292 308 3.8E-66 T 26-04-2017 A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 PRINTS PR00145 Argininosuccinate lyase family signature 327 346 3.8E-66 T 26-04-2017 A4V04_RS07185 88faf80e9bebc9604313e20cc063ee1b 476 ProSitePatterns PS00163 Fumarate lyases signature. 292 301 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS08160 c64495771cfa877ff16f5efc744e6ca5 325 SUPERFAMILY SSF53474 26 301 5.65E-32 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS08160 c64495771cfa877ff16f5efc744e6ca5 325 Pfam PF00561 alpha/beta hydrolase fold 63 304 1.9E-10 T 26-04-2017 IPR000073 Alpha/beta hydrolase fold-1 A4V04_RS08160 c64495771cfa877ff16f5efc744e6ca5 325 PIRSF PIRSF005211 1 325 2.1E-90 T 26-04-2017 IPR012020 AB hydrolase 4 family A4V04_RS08160 c64495771cfa877ff16f5efc744e6ca5 325 Gene3D G3DSA:3.40.50.1820 35 303 6.0E-20 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 4.5E-16 T 26-04-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 SUPERFAMILY SSF55261 292 417 7.03E-42 T 26-04-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 481 497 5.0E-26 T 26-04-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 525 539 5.0E-26 T 26-04-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 221 5.0E-26 T 26-04-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 5.0E-26 T 26-04-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 Gene3D G3DSA:3.30.1360.30 278 416 1.1E-44 T 26-04-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 SUPERFAMILY SSF50249 1 105 6.86E-32 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 Pfam PF02938 GAD domain 312 408 1.5E-26 T 26-04-2017 IPR029351 GAD domain Reactome: R-HSA-379726 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 SUPERFAMILY SSF55681 110 293 7.17E-105 T 26-04-2017 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 SUPERFAMILY SSF55681 431 592 7.17E-105 T 26-04-2017 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 Gene3D G3DSA:3.30.930.10 135 277 4.3E-113 T 26-04-2017 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 Gene3D G3DSA:3.30.930.10 417 592 4.3E-113 T 26-04-2017 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 1 570 36.148 T 26-04-2017 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 589 7.0E-242 T 26-04-2017 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 565 3.7E-108 T 26-04-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS08930 82b27ac88901e30f248cef2980581309 597 Gene3D G3DSA:2.40.50.140 1 107 2.2E-36 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS10285 bf21c66b35cbac969cf98b0ecd210631 506 Pfam PF00939 Sodium:sulfate symporter transmembrane region 38 501 8.5E-52 T 26-04-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A4V04_RS10285 bf21c66b35cbac969cf98b0ecd210631 506 PIRSF PIRSF002457 22 502 2.2E-121 T 26-04-2017 IPR030676 Citrate carrier CitT-related A4V04_RS08830 f4be28ba6fc8b4f9bf4a23bfac72617b 491 Gene3D G3DSA:1.20.200.10 99 366 4.2E-44 T 26-04-2017 A4V04_RS08830 f4be28ba6fc8b4f9bf4a23bfac72617b 491 Pfam PF00206 Lyase 59 284 2.7E-24 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS08830 f4be28ba6fc8b4f9bf4a23bfac72617b 491 Pfam PF14698 Argininosuccinate lyase C-terminal 361 438 2.0E-7 T 26-04-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS08830 f4be28ba6fc8b4f9bf4a23bfac72617b 491 Gene3D G3DSA:1.10.40.30 367 438 5.0E-9 T 26-04-2017 A4V04_RS08830 f4be28ba6fc8b4f9bf4a23bfac72617b 491 SUPERFAMILY SSF48557 28 461 2.04E-65 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS08830 f4be28ba6fc8b4f9bf4a23bfac72617b 491 PRINTS PR00145 Argininosuccinate lyase family signature 185 201 2.0E-10 T 26-04-2017 A4V04_RS08830 f4be28ba6fc8b4f9bf4a23bfac72617b 491 PRINTS PR00145 Argininosuccinate lyase family signature 134 154 2.0E-10 T 26-04-2017 A4V04_RS08830 f4be28ba6fc8b4f9bf4a23bfac72617b 491 PRINTS PR00145 Argininosuccinate lyase family signature 93 115 2.0E-10 T 26-04-2017 A4V04_RS08830 f4be28ba6fc8b4f9bf4a23bfac72617b 491 PRINTS PR00145 Argininosuccinate lyase family signature 270 286 2.0E-10 T 26-04-2017 A4V04_RS08915 b627202ce82e1f46874508bc7923477b 280 SUPERFAMILY SSF56655 23 276 2.49E-53 T 26-04-2017 A4V04_RS08915 b627202ce82e1f46874508bc7923477b 280 Gene3D G3DSA:3.40.190.80 173 277 1.2E-18 T 26-04-2017 A4V04_RS08915 b627202ce82e1f46874508bc7923477b 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 72 88 1.2E-13 T 26-04-2017 IPR000760 Inositol monophosphatase GO:0046854 A4V04_RS08915 b627202ce82e1f46874508bc7923477b 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 95 111 1.2E-13 T 26-04-2017 IPR000760 Inositol monophosphatase GO:0046854 A4V04_RS08915 b627202ce82e1f46874508bc7923477b 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 227 251 1.2E-13 T 26-04-2017 IPR000760 Inositol monophosphatase GO:0046854 A4V04_RS08915 b627202ce82e1f46874508bc7923477b 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 50 70 1.2E-13 T 26-04-2017 IPR000760 Inositol monophosphatase GO:0046854 A4V04_RS08915 b627202ce82e1f46874508bc7923477b 280 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 95 108 - T 26-04-2017 IPR020583 Inositol monophosphatase, metal-binding site A4V04_RS08915 b627202ce82e1f46874508bc7923477b 280 Gene3D G3DSA:3.30.540.10 26 172 1.5E-28 T 26-04-2017 A4V04_RS08915 b627202ce82e1f46874508bc7923477b 280 Pfam PF00459 Inositol monophosphatase family 46 264 3.6E-33 T 26-04-2017 IPR000760 Inositol monophosphatase GO:0046854 A4V04_RS03495 b7e7f14468f06ad0fd007c80e4692000 291 Gene3D G3DSA:3.90.226.10 22 287 1.2E-69 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS03495 b7e7f14468f06ad0fd007c80e4692000 291 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 285 3.5E-126 T 26-04-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS03495 b7e7f14468f06ad0fd007c80e4692000 291 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 284 37.421 T 26-04-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS03495 b7e7f14468f06ad0fd007c80e4692000 291 SUPERFAMILY SSF52096 28 284 1.09E-81 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS03495 b7e7f14468f06ad0fd007c80e4692000 291 Pfam PF01039 Carboxyl transferase domain 101 244 3.9E-14 T 26-04-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4V04_RS03495 b7e7f14468f06ad0fd007c80e4692000 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 166 184 3.9E-37 T 26-04-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS03495 b7e7f14468f06ad0fd007c80e4692000 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 232 243 3.9E-37 T 26-04-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS03495 b7e7f14468f06ad0fd007c80e4692000 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 132 146 3.9E-37 T 26-04-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS03495 b7e7f14468f06ad0fd007c80e4692000 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 254 263 3.9E-37 T 26-04-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS03495 b7e7f14468f06ad0fd007c80e4692000 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 203 220 3.9E-37 T 26-04-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4V04_RS10925 956cb09cd03e5fce8edeaa92c37beedf 203 SUPERFAMILY SSF46894 134 201 1.43E-18 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS10925 956cb09cd03e5fce8edeaa92c37beedf 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 193 4.7E-18 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10925 956cb09cd03e5fce8edeaa92c37beedf 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 3.9E-13 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10925 956cb09cd03e5fce8edeaa92c37beedf 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 3.9E-13 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10925 956cb09cd03e5fce8edeaa92c37beedf 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 3.9E-13 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10925 956cb09cd03e5fce8edeaa92c37beedf 203 Gene3D G3DSA:1.10.10.10 146 202 1.2E-20 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10925 956cb09cd03e5fce8edeaa92c37beedf 203 Pfam PF00072 Response regulator receiver domain 7 115 6.8E-25 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS10925 956cb09cd03e5fce8edeaa92c37beedf 203 Gene3D G3DSA:3.40.50.2300 7 145 6.6E-30 T 26-04-2017 A4V04_RS10925 956cb09cd03e5fce8edeaa92c37beedf 203 SMART SM00448 5 115 3.1E-25 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS10925 956cb09cd03e5fce8edeaa92c37beedf 203 ProSitePatterns PS00622 LuxR-type HTH domain signature. 157 184 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10925 956cb09cd03e5fce8edeaa92c37beedf 203 SUPERFAMILY SSF52172 7 131 5.12E-29 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS10925 956cb09cd03e5fce8edeaa92c37beedf 203 SMART SM00421 140 197 7.6E-20 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS06920 4f94152baadb44f207269114a8c2f561 1153 SUPERFAMILY SSF47781 832 869 1.22E-7 T 26-04-2017 IPR010994 RuvA domain 2-like A4V04_RS06920 4f94152baadb44f207269114a8c2f561 1153 Pfam PF14579 Helix-hairpin-helix motif 803 891 3.5E-26 T 26-04-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS06920 4f94152baadb44f207269114a8c2f561 1153 Gene3D G3DSA:1.10.150.280 831 867 1.6E-8 T 26-04-2017 A4V04_RS06920 4f94152baadb44f207269114a8c2f561 1153 SMART SM00481 6 73 6.6E-20 T 26-04-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 A4V04_RS06920 4f94152baadb44f207269114a8c2f561 1153 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1020 0.0 T 26-04-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS06920 4f94152baadb44f207269114a8c2f561 1153 Pfam PF02811 PHP domain 7 173 2.6E-38 T 26-04-2017 IPR004013 PHP domain GO:0003824 A4V04_RS06920 4f94152baadb44f207269114a8c2f561 1153 Gene3D G3DSA:3.20.20.140 5 256 1.0E-20 T 26-04-2017 A4V04_RS06920 4f94152baadb44f207269114a8c2f561 1153 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 292 730 1.4E-160 T 26-04-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS06920 4f94152baadb44f207269114a8c2f561 1153 SUPERFAMILY SSF89550 5 263 1.8E-13 T 26-04-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4V04_RS08145 61c01ed4447258c2cb53de39849a7173 427 Pfam PF00672 HAMP domain 135 210 1.5E-7 T 26-04-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4V04_RS08145 61c01ed4447258c2cb53de39849a7173 427 SMART SM00388 215 281 2.0E-12 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS08145 61c01ed4447258c2cb53de39849a7173 427 SUPERFAMILY SSF55874 274 424 7.86E-28 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS08145 61c01ed4447258c2cb53de39849a7173 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 424 2.4E-16 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS08145 61c01ed4447258c2cb53de39849a7173 427 SUPERFAMILY SSF47384 198 278 3.53E-13 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS08145 61c01ed4447258c2cb53de39849a7173 427 SMART SM00387 323 427 1.1E-23 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS08145 61c01ed4447258c2cb53de39849a7173 427 Gene3D G3DSA:1.10.287.130 210 277 3.7E-12 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS08145 61c01ed4447258c2cb53de39849a7173 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 406 2.3E-7 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS08145 61c01ed4447258c2cb53de39849a7173 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 2.3E-7 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS08145 61c01ed4447258c2cb53de39849a7173 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 383 2.3E-7 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS08145 61c01ed4447258c2cb53de39849a7173 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 425 2.3E-7 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS08145 61c01ed4447258c2cb53de39849a7173 427 Gene3D G3DSA:3.30.565.10 286 424 3.9E-28 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS08145 61c01ed4447258c2cb53de39849a7173 427 Pfam PF00512 His Kinase A (phospho-acceptor) domain 221 278 7.9E-12 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS09055 cf244f36f30a36cc9335cb2fba696b76 427 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 22 420 1.1E-102 T 26-04-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A4V04_RS09055 cf244f36f30a36cc9335cb2fba696b76 427 Pfam PF00860 Permease family 27 395 1.9E-92 T 26-04-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A4V04_RS12520 b1f9944710b195ae792f934720712aab 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 214 1.8E-22 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS12520 b1f9944710b195ae792f934720712aab 217 Gene3D G3DSA:1.10.3720.10 7 214 8.2E-42 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS12520 b1f9944710b195ae792f934720712aab 217 SUPERFAMILY SSF161098 8 201 3.27E-48 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS12265 9a7967f36fa217a2215c2e1f910cee6a 345 PIRSF PIRSF005303 15 344 1.3E-75 T 26-04-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A4V04_RS12265 9a7967f36fa217a2215c2e1f910cee6a 345 Gene3D G3DSA:3.90.650.10 169 344 3.6E-41 T 26-04-2017 IPR010918 AIR synthase-related protein, C-terminal domain A4V04_RS12265 9a7967f36fa217a2215c2e1f910cee6a 345 Gene3D G3DSA:3.30.1330.10 17 164 3.8E-39 T 26-04-2017 IPR016188 PurM-like, N-terminal domain A4V04_RS12265 9a7967f36fa217a2215c2e1f910cee6a 345 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 322 1.8E-6 T 26-04-2017 IPR010918 AIR synthase-related protein, C-terminal domain A4V04_RS12265 9a7967f36fa217a2215c2e1f910cee6a 345 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 19 341 26.635 T 26-04-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A4V04_RS12265 9a7967f36fa217a2215c2e1f910cee6a 345 SUPERFAMILY SSF56042 168 322 5.65E-36 T 26-04-2017 IPR010918 AIR synthase-related protein, C-terminal domain A4V04_RS12265 9a7967f36fa217a2215c2e1f910cee6a 345 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 20 344 1.9E-87 T 26-04-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A4V04_RS12265 9a7967f36fa217a2215c2e1f910cee6a 345 SUPERFAMILY SSF55326 18 163 1.5E-30 T 26-04-2017 A4V04_RS12265 9a7967f36fa217a2215c2e1f910cee6a 345 Pfam PF00586 AIR synthase related protein, N-terminal domain 46 162 1.9E-21 T 26-04-2017 IPR016188 PurM-like, N-terminal domain A4V04_RS10945 ee7f484c3f44bd8c3a5fd95f43450c44 347 Pfam PF01738 Dienelactone hydrolase family 66 178 2.7E-7 T 26-04-2017 IPR002925 Dienelactone hydrolase GO:0016787 A4V04_RS10945 ee7f484c3f44bd8c3a5fd95f43450c44 347 Gene3D G3DSA:3.40.50.1820 50 347 2.4E-70 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS10945 ee7f484c3f44bd8c3a5fd95f43450c44 347 SUPERFAMILY SSF53474 219 246 1.34E-48 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS10945 ee7f484c3f44bd8c3a5fd95f43450c44 347 SUPERFAMILY SSF53474 276 347 1.34E-48 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS10945 ee7f484c3f44bd8c3a5fd95f43450c44 347 SUPERFAMILY SSF53474 18 189 1.34E-48 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS07700 95a9f7da5e881625c73170906cacb246 663 Pfam PF00773 RNB domain 243 471 1.3E-28 T 26-04-2017 A4V04_RS07700 95a9f7da5e881625c73170906cacb246 663 Pfam PF00773 RNB domain 472 515 6.8E-9 T 26-04-2017 A4V04_RS07700 95a9f7da5e881625c73170906cacb246 663 SMART SM00955 238 517 1.7E-51 T 26-04-2017 A4V04_RS07700 95a9f7da5e881625c73170906cacb246 663 SUPERFAMILY SSF50249 224 561 3.03E-68 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 SUPERFAMILY SSF48557 1 456 3.46E-106 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 PRINTS PR00145 Argininosuccinate lyase family signature 171 191 5.6E-7 T 26-04-2017 A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 PRINTS PR00145 Argininosuccinate lyase family signature 313 329 5.6E-7 T 26-04-2017 A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 PRINTS PR00145 Argininosuccinate lyase family signature 229 245 5.6E-7 T 26-04-2017 A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 PRINTS PR00145 Argininosuccinate lyase family signature 130 152 5.6E-7 T 26-04-2017 A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 Gene3D G3DSA:1.10.40.30 414 459 1.8E-9 T 26-04-2017 A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 Pfam PF10415 Fumarase C C-terminus 404 456 2.3E-9 T 26-04-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 ProSitePatterns PS00163 Fumarate lyases signature. 313 322 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 PRINTS PR00149 Fumarate lyase superfamily signature 313 329 2.2E-24 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 PRINTS PR00149 Fumarate lyase superfamily signature 131 149 2.2E-24 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 PRINTS PR00149 Fumarate lyase superfamily signature 176 194 2.2E-24 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 PRINTS PR00149 Fumarate lyase superfamily signature 267 294 2.2E-24 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 Gene3D G3DSA:1.20.200.10 136 413 1.5E-71 T 26-04-2017 A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 Gene3D G3DSA:1.10.275.10 1 135 1.7E-39 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS01590 d663921d8764096fb7bf49c55428bfa6 474 Pfam PF00206 Lyase 10 336 2.8E-73 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS09105 b7279bccd7b90f884fed3739ab8b0af9 607 SUPERFAMILY SSF52540 288 483 1.02E-44 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09105 b7279bccd7b90f884fed3739ab8b0af9 607 Pfam PF12848 ABC transporter 197 269 4.3E-10 T 26-04-2017 IPR032781 ABC-transporter extension domain A4V04_RS09105 b7279bccd7b90f884fed3739ab8b0af9 607 SUPERFAMILY SSF52540 6 219 3.34E-44 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09105 b7279bccd7b90f884fed3739ab8b0af9 607 Gene3D G3DSA:3.40.50.300 294 520 3.9E-44 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09105 b7279bccd7b90f884fed3739ab8b0af9 607 Gene3D G3DSA:3.40.50.300 6 254 7.5E-50 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09105 b7279bccd7b90f884fed3739ab8b0af9 607 ProSitePatterns PS00211 ABC transporters family signature. 414 428 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS09105 b7279bccd7b90f884fed3739ab8b0af9 607 SMART SM00382 317 487 3.1E-11 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS09105 b7279bccd7b90f884fed3739ab8b0af9 607 SMART SM00382 28 212 2.9E-12 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS09105 b7279bccd7b90f884fed3739ab8b0af9 607 Pfam PF00005 ABC transporter 19 155 2.4E-21 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS09105 b7279bccd7b90f884fed3739ab8b0af9 607 Pfam PF00005 ABC transporter 309 442 3.5E-24 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS09105 b7279bccd7b90f884fed3739ab8b0af9 607 Pfam PF16326 ABC transporter C-terminal domain 530 598 3.3E-16 T 26-04-2017 IPR032524 ABC transporter Uup, C-terminal GO:0003677 A4V04_RS11960 72c2c00c5236d8a6264e46ea80c02df0 409 SUPERFAMILY SSF56266 16 406 1.83E-136 T 26-04-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4V04_RS11960 72c2c00c5236d8a6264e46ea80c02df0 409 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 409 152.511 T 26-04-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4V04_RS11960 72c2c00c5236d8a6264e46ea80c02df0 409 Gene3D G3DSA:3.60.70.12 12 280 4.4E-95 T 26-04-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4V04_RS11960 72c2c00c5236d8a6264e46ea80c02df0 409 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 24 407 9.0E-138 T 26-04-2017 A4V04_RS11960 72c2c00c5236d8a6264e46ea80c02df0 409 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 11 409 1.1E-123 T 26-04-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4V04_RS11960 72c2c00c5236d8a6264e46ea80c02df0 409 Pfam PF01960 ArgJ family 23 409 9.9E-142 T 26-04-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4V04_RS00150 5e383ab15e2b1fd5d263b6a381b190e4 550 Gene3D G3DSA:3.90.10.10 24 85 4.8E-8 T 26-04-2017 A4V04_RS00150 5e383ab15e2b1fd5d263b6a381b190e4 550 SUPERFAMILY SSF48695 24 95 2.35E-9 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS00150 5e383ab15e2b1fd5d263b6a381b190e4 550 SUPERFAMILY SSF48695 310 547 1.16E-31 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS00150 5e383ab15e2b1fd5d263b6a381b190e4 550 SUPERFAMILY SSF48695 199 279 1.16E-31 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS00150 5e383ab15e2b1fd5d263b6a381b190e4 550 Gene3D G3DSA:1.20.140.10 432 548 3.9E-4 T 26-04-2017 A4V04_RS00150 5e383ab15e2b1fd5d263b6a381b190e4 550 Pfam PF02335 Cytochrome c552 199 546 2.9E-14 T 26-04-2017 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 A4V04_RS00150 5e383ab15e2b1fd5d263b6a381b190e4 550 Gene3D G3DSA:1.10.710.10 189 322 8.1E-16 T 26-04-2017 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 A4V04_RS00150 5e383ab15e2b1fd5d263b6a381b190e4 550 Gene3D G3DSA:1.10.710.10 86 114 8.1E-16 T 26-04-2017 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 A4V04_RS00150 5e383ab15e2b1fd5d263b6a381b190e4 550 Gene3D G3DSA:1.10.710.10 389 431 8.1E-16 T 26-04-2017 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 A4V04_RS13215 a720c87d86d9372dc0e4caad72510cb5 157 Pfam PF02082 Transcriptional regulator 1 83 1.5E-26 T 26-04-2017 IPR000944 Transcription regulator Rrf2-type A4V04_RS13215 a720c87d86d9372dc0e4caad72510cb5 157 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 2.0E-39 T 26-04-2017 IPR000944 Transcription regulator Rrf2-type A4V04_RS13215 a720c87d86d9372dc0e4caad72510cb5 157 SUPERFAMILY SSF46785 2 133 2.08E-31 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS13215 a720c87d86d9372dc0e4caad72510cb5 157 Gene3D G3DSA:1.10.10.10 1 134 4.1E-32 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07940 f98225b11b2622d558ca745c8e7b1e1a 425 Pfam PF09861 Domain of unknown function (DUF2088) 8 209 5.6E-64 T 26-04-2017 IPR018657 Domain of unknown function DUF2088 A4V04_RS05330 a0618c9babc6efee8a47b356a44a2c22 388 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 1 378 1.6E-134 T 26-04-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A4V04_RS05330 a0618c9babc6efee8a47b356a44a2c22 388 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 207 244 - T 26-04-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4V04_RS05330 a0618c9babc6efee8a47b356a44a2c22 388 Gene3D G3DSA:3.90.1150.10 290 380 1.9E-34 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS05330 a0618c9babc6efee8a47b356a44a2c22 388 Gene3D G3DSA:3.90.1150.10 1 43 1.9E-34 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS05330 a0618c9babc6efee8a47b356a44a2c22 388 Pfam PF00202 Aminotransferase class-III 9 376 3.8E-110 T 26-04-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4V04_RS05330 a0618c9babc6efee8a47b356a44a2c22 388 Gene3D G3DSA:3.40.640.10 44 288 1.5E-81 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS05330 a0618c9babc6efee8a47b356a44a2c22 388 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 1 380 41.459 T 26-04-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A4V04_RS05330 a0618c9babc6efee8a47b356a44a2c22 388 SUPERFAMILY SSF53383 2 378 2.78E-117 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS00670 b016da6c22c44f655df149792ae409fb 225 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 10 165 1.6E-19 T 26-04-2017 IPR007296 Domain of unknown function DUF403 A4V04_RS12410 badb41887215063eda96dc9b685923a8 388 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 1.8E-154 T 26-04-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS12410 badb41887215063eda96dc9b685923a8 388 Gene3D G3DSA:3.30.1490.20 22 95 5.3E-32 T 26-04-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4V04_RS12410 badb41887215063eda96dc9b685923a8 388 Pfam PF00549 CoA-ligase 262 381 7.0E-25 T 26-04-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS12410 badb41887215063eda96dc9b685923a8 388 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 40.559 T 26-04-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS12410 badb41887215063eda96dc9b685923a8 388 Gene3D G3DSA:3.40.50.261 241 385 6.4E-63 T 26-04-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS12410 badb41887215063eda96dc9b685923a8 388 Pfam PF08442 ATP-grasp domain 2 202 4.4E-76 T 26-04-2017 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS12410 badb41887215063eda96dc9b685923a8 388 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 26-04-2017 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS12410 badb41887215063eda96dc9b685923a8 388 SUPERFAMILY SSF52210 239 385 5.63E-53 T 26-04-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS12410 badb41887215063eda96dc9b685923a8 388 SUPERFAMILY SSF56059 1 238 3.14E-76 T 26-04-2017 A4V04_RS12410 badb41887215063eda96dc9b685923a8 388 Gene3D G3DSA:3.30.470.20 96 239 6.0E-55 T 26-04-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4V04_RS12410 badb41887215063eda96dc9b685923a8 388 PIRSF PIRSF001554 1 388 1.7E-148 T 26-04-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS04040 395831e9b0d94d4651f48ae6d7afd19d 268 SUPERFAMILY SSF55729 91 247 1.54E-18 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS04040 395831e9b0d94d4651f48ae6d7afd19d 268 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 28 96 7.2E-11 T 26-04-2017 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 A4V04_RS04040 395831e9b0d94d4651f48ae6d7afd19d 268 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 118 241 1.1E-33 T 26-04-2017 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 A4V04_RS04040 395831e9b0d94d4651f48ae6d7afd19d 268 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 6 250 35.8 T 26-04-2017 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic A4V04_RS04040 395831e9b0d94d4651f48ae6d7afd19d 268 PIRSF PIRSF037208 14 260 6.2E-78 T 26-04-2017 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic A4V04_RS03310 2e717451d25d466b8749429af6de3d63 615 Gene3D G3DSA:3.40.50.980 18 198 9.0E-36 T 26-04-2017 A4V04_RS03310 2e717451d25d466b8749429af6de3d63 615 ProSitePatterns PS00455 Putative AMP-binding domain signature. 192 203 - T 26-04-2017 IPR020845 AMP-binding, conserved site A4V04_RS03310 2e717451d25d466b8749429af6de3d63 615 Gene3D G3DSA:3.30.300.30 476 597 1.5E-5 T 26-04-2017 A4V04_RS03310 2e717451d25d466b8749429af6de3d63 615 Pfam PF00501 AMP-binding enzyme 25 478 1.8E-93 T 26-04-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4V04_RS03310 2e717451d25d466b8749429af6de3d63 615 PRINTS PR00154 AMP-binding signature 187 198 5.7E-5 T 26-04-2017 IPR020459 AMP-binding A4V04_RS03310 2e717451d25d466b8749429af6de3d63 615 PRINTS PR00154 AMP-binding signature 199 207 5.7E-5 T 26-04-2017 IPR020459 AMP-binding A4V04_RS03310 2e717451d25d466b8749429af6de3d63 615 Gene3D G3DSA:2.30.38.10 412 472 1.4E-17 T 26-04-2017 A4V04_RS03310 2e717451d25d466b8749429af6de3d63 615 SUPERFAMILY SSF56801 348 607 2.62E-119 T 26-04-2017 A4V04_RS03310 2e717451d25d466b8749429af6de3d63 615 SUPERFAMILY SSF56801 16 295 2.62E-119 T 26-04-2017 A4V04_RS03310 2e717451d25d466b8749429af6de3d63 615 Gene3D G3DSA:3.40.50.980 345 404 1.2E-35 T 26-04-2017 A4V04_RS03310 2e717451d25d466b8749429af6de3d63 615 Gene3D G3DSA:3.40.50.980 199 290 1.2E-35 T 26-04-2017 A4V04_RS03125 aff785cc3f909cfc950b4d1a8a955938 432 Pfam PF04165 Protein of unknown function (DUF401) 44 418 3.0E-23 T 26-04-2017 IPR007294 Protein of unknown function DUF401 A4V04_RS12780 bc27a9929e319be44d899d5c43d8c720 360 Gene3D G3DSA:1.20.1090.10 172 353 1.6E-63 T 26-04-2017 A4V04_RS12780 bc27a9929e319be44d899d5c43d8c720 360 SUPERFAMILY SSF56796 6 353 7.46E-112 T 26-04-2017 A4V04_RS12780 bc27a9929e319be44d899d5c43d8c720 360 Gene3D G3DSA:3.40.50.1970 4 171 9.1E-65 T 26-04-2017 A4V04_RS12780 bc27a9929e319be44d899d5c43d8c720 360 PIRSF PIRSF001455 3 359 3.1E-112 T 26-04-2017 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4V04_RS12780 bc27a9929e319be44d899d5c43d8c720 360 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 355 40.08 T 26-04-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4V04_RS12780 bc27a9929e319be44d899d5c43d8c720 360 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 351 1.9E-117 T 26-04-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4V04_RS12780 bc27a9929e319be44d899d5c43d8c720 360 Pfam PF01761 3-dehydroquinate synthase 67 323 2.7E-103 T 26-04-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4V04_RS05445 a9b79ba9e3b5c2fb501780c846b4f6e9 901 Gene3D G3DSA:3.40.50.300 332 390 1.0E-26 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05445 a9b79ba9e3b5c2fb501780c846b4f6e9 901 Gene3D G3DSA:3.40.50.300 513 514 1.0E-26 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05445 a9b79ba9e3b5c2fb501780c846b4f6e9 901 Gene3D G3DSA:3.40.50.300 776 805 1.0E-26 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05445 a9b79ba9e3b5c2fb501780c846b4f6e9 901 Gene3D G3DSA:3.40.50.300 686 742 1.0E-26 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05445 a9b79ba9e3b5c2fb501780c846b4f6e9 901 Gene3D G3DSA:3.40.50.300 423 459 1.0E-26 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05445 a9b79ba9e3b5c2fb501780c846b4f6e9 901 Pfam PF13245 Part of AAA domain 359 447 2.1E-7 T 26-04-2017 A4V04_RS05445 a9b79ba9e3b5c2fb501780c846b4f6e9 901 SUPERFAMILY SSF52540 337 389 4.48E-27 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05445 a9b79ba9e3b5c2fb501780c846b4f6e9 901 SUPERFAMILY SSF52540 423 451 4.48E-27 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05445 a9b79ba9e3b5c2fb501780c846b4f6e9 901 SUPERFAMILY SSF52540 665 891 4.48E-27 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05445 a9b79ba9e3b5c2fb501780c846b4f6e9 901 Pfam PF13086 AAA domain 667 726 1.2E-9 T 26-04-2017 A4V04_RS01660 7d416709d99e176662dcc3cc3051ec2e 146 SUPERFAMILY SSF48557 1 144 3.3E-29 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS01660 7d416709d99e176662dcc3cc3051ec2e 146 Pfam PF00206 Lyase 11 144 2.4E-16 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS01660 7d416709d99e176662dcc3cc3051ec2e 146 Gene3D G3DSA:1.10.275.10 1 135 8.9E-40 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS05885 4a7810a6ad6774565a0b14e17065f7de 250 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 14 238 39.583 T 26-04-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4V04_RS05885 4a7810a6ad6774565a0b14e17065f7de 250 Pfam PF01255 Putative undecaprenyl diphosphate synthase 21 237 2.2E-79 T 26-04-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4V04_RS05885 4a7810a6ad6774565a0b14e17065f7de 250 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 14 237 1.4E-86 T 26-04-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4V04_RS05885 4a7810a6ad6774565a0b14e17065f7de 250 SUPERFAMILY SSF64005 12 233 1.31E-84 T 26-04-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4V04_RS05885 4a7810a6ad6774565a0b14e17065f7de 250 Gene3D G3DSA:3.40.1180.10 10 245 9.4E-96 T 26-04-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4V04_RS02835 7b502ac243b983fcb2c2e74ea8c97d03 1121 PRINTS PR01484 Pertactin virulence factor family signature 1009 1032 5.0E-11 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02835 7b502ac243b983fcb2c2e74ea8c97d03 1121 PRINTS PR01484 Pertactin virulence factor family signature 852 872 5.0E-11 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02835 7b502ac243b983fcb2c2e74ea8c97d03 1121 PRINTS PR01484 Pertactin virulence factor family signature 832 850 5.0E-11 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02835 7b502ac243b983fcb2c2e74ea8c97d03 1121 PRINTS PR01484 Pertactin virulence factor family signature 990 1007 5.0E-11 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02835 7b502ac243b983fcb2c2e74ea8c97d03 1121 PRINTS PR01484 Pertactin virulence factor family signature 893 917 5.0E-11 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02835 7b502ac243b983fcb2c2e74ea8c97d03 1121 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 777 1121 2.8E-49 T 26-04-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 A4V04_RS02835 7b502ac243b983fcb2c2e74ea8c97d03 1121 Gene3D G3DSA:2.40.128.130 818 1121 1.6E-67 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02835 7b502ac243b983fcb2c2e74ea8c97d03 1121 SMART SM00869 852 1110 5.3E-26 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02835 7b502ac243b983fcb2c2e74ea8c97d03 1121 Pfam PF03797 Autotransporter beta-domain 854 1102 4.4E-32 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02835 7b502ac243b983fcb2c2e74ea8c97d03 1121 SUPERFAMILY SSF103515 827 1121 3.27E-37 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS00080 cae5dc9af32bb24b1137b5f3048cc9e1 188 SUPERFAMILY SSF55021 94 179 2.59E-8 T 26-04-2017 A4V04_RS00080 cae5dc9af32bb24b1137b5f3048cc9e1 188 Gene3D G3DSA:3.30.70.260 93 185 2.0E-14 T 26-04-2017 A4V04_RS00080 cae5dc9af32bb24b1137b5f3048cc9e1 188 Gene3D G3DSA:3.30.70.260 3 73 8.5E-16 T 26-04-2017 A4V04_RS00080 cae5dc9af32bb24b1137b5f3048cc9e1 188 Pfam PF13740 ACT domain 4 75 6.6E-12 T 26-04-2017 A4V04_RS00080 cae5dc9af32bb24b1137b5f3048cc9e1 188 SUPERFAMILY SSF55021 3 79 7.34E-14 T 26-04-2017 A4V04_RS07305 4b391cd4293023b819cb0031a263cfac 331 Pfam PF13280 WYL domain 158 309 8.1E-22 T 26-04-2017 IPR026881 WYL domain A4V04_RS12715 f41768b253e4d076d79182118288fa2e 268 SUPERFAMILY SSF52540 7 238 2.73E-62 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12715 f41768b253e4d076d79182118288fa2e 268 Gene3D G3DSA:3.40.50.300 2 242 1.1E-67 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12715 f41768b253e4d076d79182118288fa2e 268 SMART SM00382 32 229 2.7E-8 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS12715 f41768b253e4d076d79182118288fa2e 268 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS12715 f41768b253e4d076d79182118288fa2e 268 Pfam PF00005 ABC transporter 23 172 8.8E-28 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS09785 36090aaf77fc69402c299dc0e94a1453 360 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 311 335 - T 26-04-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 A4V04_RS09785 36090aaf77fc69402c299dc0e94a1453 360 Pfam PF01098 Cell cycle protein 11 353 6.8E-99 T 26-04-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 A4V04_RS09785 36090aaf77fc69402c299dc0e94a1453 360 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 8 351 4.8E-122 T 26-04-2017 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 A4V04_RS12295 6931d30053d3de3b003db7affe770d89 421 PIRSF PIRSF000412 2 421 3.5E-172 T 26-04-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4V04_RS12295 6931d30053d3de3b003db7affe770d89 421 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 226 242 - T 26-04-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4V04_RS12295 6931d30053d3de3b003db7affe770d89 421 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 419 51.664 T 26-04-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4V04_RS12295 6931d30053d3de3b003db7affe770d89 421 Gene3D G3DSA:3.40.640.10 37 287 2.6E-106 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS12295 6931d30053d3de3b003db7affe770d89 421 Pfam PF00464 Serine hydroxymethyltransferase 8 388 1.5E-178 T 26-04-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4V04_RS12295 6931d30053d3de3b003db7affe770d89 421 SUPERFAMILY SSF53383 6 419 1.48E-182 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS12295 6931d30053d3de3b003db7affe770d89 421 Gene3D G3DSA:3.90.1150.10 288 419 6.6E-59 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS10170 5b82ab8e7be24a4261578f8c23863802 323 Gene3D G3DSA:3.40.190.10 126 231 2.2E-5 T 26-04-2017 A4V04_RS10170 5b82ab8e7be24a4261578f8c23863802 323 SUPERFAMILY SSF53850 99 285 9.41E-15 T 26-04-2017 A4V04_RS10170 5b82ab8e7be24a4261578f8c23863802 323 Gene3D G3DSA:1.10.10.10 16 84 4.0E-16 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10170 5b82ab8e7be24a4261578f8c23863802 323 SUPERFAMILY SSF46785 16 79 1.87E-14 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10170 5b82ab8e7be24a4261578f8c23863802 323 Pfam PF03466 LysR substrate binding domain 100 285 1.7E-11 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS10170 5b82ab8e7be24a4261578f8c23863802 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 2.0E-5 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10170 5b82ab8e7be24a4261578f8c23863802 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 2.0E-5 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10170 5b82ab8e7be24a4261578f8c23863802 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 2.0E-5 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10170 5b82ab8e7be24a4261578f8c23863802 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 70 6.9E-14 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09625 1b0c2892bf1504ae8e780532ff127eff 380 Pfam PF07687 Peptidase dimerisation domain 173 279 1.3E-11 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS09625 1b0c2892bf1504ae8e780532ff127eff 380 Pfam PF01546 Peptidase family M20/M25/M40 69 376 3.3E-28 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS09625 1b0c2892bf1504ae8e780532ff127eff 380 Gene3D G3DSA:3.40.630.10 1 184 1.8E-53 T 26-04-2017 A4V04_RS09625 1b0c2892bf1504ae8e780532ff127eff 380 Gene3D G3DSA:3.40.630.10 320 379 1.8E-53 T 26-04-2017 A4V04_RS09625 1b0c2892bf1504ae8e780532ff127eff 380 Gene3D G3DSA:3.30.70.360 185 279 7.7E-16 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS09625 1b0c2892bf1504ae8e780532ff127eff 380 SUPERFAMILY SSF53187 2 175 4.45E-52 T 26-04-2017 A4V04_RS09625 1b0c2892bf1504ae8e780532ff127eff 380 SUPERFAMILY SSF53187 296 379 4.45E-52 T 26-04-2017 A4V04_RS09625 1b0c2892bf1504ae8e780532ff127eff 380 SUPERFAMILY SSF55031 175 286 2.88E-13 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS02195 dc175813ac2ca6e00125b276867448c0 1363 SUPERFAMILY SSF47413 10 82 1.05E-15 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS02195 dc175813ac2ca6e00125b276867448c0 1363 SMART SM00530 14 70 6.6E-8 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS02195 dc175813ac2ca6e00125b276867448c0 1363 Pfam PF01381 Helix-turn-helix 19 69 1.7E-8 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS02195 dc175813ac2ca6e00125b276867448c0 1363 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 7 81 3.4E-16 T 26-04-2017 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 A4V04_RS02195 dc175813ac2ca6e00125b276867448c0 1363 Gene3D G3DSA:1.10.260.40 6 80 6.3E-21 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS02265 46555f7be79672dc510aec50217b0e9c 241 SUPERFAMILY SSF48613 28 239 9.07E-43 T 26-04-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4V04_RS02265 46555f7be79672dc510aec50217b0e9c 241 Pfam PF03070 TENA/THI-4/PQQC family 41 238 9.9E-26 T 26-04-2017 IPR004305 Thiaminase-2/PQQC A4V04_RS02265 46555f7be79672dc510aec50217b0e9c 241 Gene3D G3DSA:1.20.910.10 27 239 1.4E-44 T 26-04-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4V04_RS04820 2aa9d049a71d14743b68eea4a1ae700e 497 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 5 489 7.4E-204 T 26-04-2017 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 A4V04_RS04820 2aa9d049a71d14743b68eea4a1ae700e 497 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 435 8.9E-103 T 26-04-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A4V04_RS04820 2aa9d049a71d14743b68eea4a1ae700e 497 Pfam PF00474 Sodium:solute symporter family 33 435 1.2E-116 T 26-04-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A4V04_RS01715 9d599aefb0f629b6ae68a38d16a0517e 238 SUPERFAMILY SSF140931 73 233 1.02E-18 T 26-04-2017 IPR003812 Fido domain A4V04_RS01715 9d599aefb0f629b6ae68a38d16a0517e 238 Pfam PF02661 Fic/DOC family 98 191 1.0E-9 T 26-04-2017 IPR003812 Fido domain A4V04_RS01715 9d599aefb0f629b6ae68a38d16a0517e 238 Gene3D G3DSA:1.10.3290.10 47 231 8.6E-23 T 26-04-2017 IPR003812 Fido domain A4V04_RS04910 3106a016c1ecbedb594c6a958b57be02 110 SMART SM00528 56 100 9.8E-10 T 26-04-2017 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 A4V04_RS04910 3106a016c1ecbedb594c6a958b57be02 110 Gene3D G3DSA:4.10.430.10 64 100 3.1E-13 T 26-04-2017 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 A4V04_RS04910 3106a016c1ecbedb594c6a958b57be02 110 SUPERFAMILY SSF81273 62 100 1.1E-9 T 26-04-2017 A4V04_RS04910 3106a016c1ecbedb594c6a958b57be02 110 Pfam PF00816 H-NS histone family 11 94 1.2E-20 T 26-04-2017 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 A4V04_RS05070 f73d1940c3f7215c9a97f5fb4ce1ea41 464 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 292 444 3.1E-32 T 26-04-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A4V04_RS05070 f73d1940c3f7215c9a97f5fb4ce1ea41 464 SUPERFAMILY SSF102735 36 156 4.32E-30 T 26-04-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A4V04_RS05070 f73d1940c3f7215c9a97f5fb4ce1ea41 464 Gene3D G3DSA:3.30.70.1050 37 147 5.3E-30 T 26-04-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A4V04_RS05070 f73d1940c3f7215c9a97f5fb4ce1ea41 464 PIRSF PIRSF003095 31 464 1.4E-115 T 26-04-2017 IPR005215 Trigger factor GO:0015031 A4V04_RS05070 f73d1940c3f7215c9a97f5fb4ce1ea41 464 Pfam PF05697 Bacterial trigger factor protein (TF) 33 171 6.9E-35 T 26-04-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A4V04_RS05070 f73d1940c3f7215c9a97f5fb4ce1ea41 464 SUPERFAMILY SSF109998 277 460 6.8E-41 T 26-04-2017 IPR027304 Trigger factor/SurA domain A4V04_RS05070 f73d1940c3f7215c9a97f5fb4ce1ea41 464 Gene3D G3DSA:3.10.50.40 166 240 2.9E-11 T 26-04-2017 A4V04_RS05070 f73d1940c3f7215c9a97f5fb4ce1ea41 464 Hamap MF_00303 Trigger factor [tig]. 29 453 19.327 T 26-04-2017 IPR005215 Trigger factor GO:0015031 A4V04_RS05070 f73d1940c3f7215c9a97f5fb4ce1ea41 464 TIGRFAM TIGR00115 tig: trigger factor 39 443 2.8E-127 T 26-04-2017 IPR005215 Trigger factor GO:0015031 A4V04_RS05070 f73d1940c3f7215c9a97f5fb4ce1ea41 464 Gene3D G3DSA:1.10.3120.10 241 420 1.3E-53 T 26-04-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A4V04_RS05070 f73d1940c3f7215c9a97f5fb4ce1ea41 464 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 186 266 1.1E-16 T 26-04-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 A4V04_RS05070 f73d1940c3f7215c9a97f5fb4ce1ea41 464 SUPERFAMILY SSF54534 162 276 1.34E-32 T 26-04-2017 A4V04_RS01575 b69d22639f7a449b371640517032b1fc 288 Pfam PF00892 EamA-like transporter family 151 276 1.2E-9 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS01575 b69d22639f7a449b371640517032b1fc 288 SUPERFAMILY SSF103481 207 275 7.98E-9 T 26-04-2017 A4V04_RS05835 dff29979a0f9d1f95f8289b1cd8083f9 207 Pfam PF01351 Ribonuclease HII 14 189 1.9E-39 T 26-04-2017 IPR024567 Ribonuclease HII/HIII domain A4V04_RS05835 dff29979a0f9d1f95f8289b1cd8083f9 207 Gene3D G3DSA:3.30.420.10 12 151 1.5E-45 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS05835 dff29979a0f9d1f95f8289b1cd8083f9 207 Hamap MF_00052_B Ribonuclease HII [rnhB]. 12 191 36.072 T 26-04-2017 IPR022898 Ribonuclease HII GO:0004523 A4V04_RS05835 dff29979a0f9d1f95f8289b1cd8083f9 207 SUPERFAMILY SSF53098 10 196 1.41E-68 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 SMART SM00475 2 262 1.1E-107 T 26-04-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 SUPERFAMILY SSF53098 332 515 7.74E-24 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 169 265 3.3E-27 T 26-04-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 SMART SM00482 688 893 2.3E-108 T 26-04-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 Gene3D G3DSA:1.10.150.20 714 819 1.7E-33 T 26-04-2017 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 SUPERFAMILY SSF56672 523 929 1.33E-150 T 26-04-2017 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 Gene3D G3DSA:3.30.70.370 820 929 1.6E-67 T 26-04-2017 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 Gene3D G3DSA:3.30.70.370 666 713 1.6E-67 T 26-04-2017 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 Gene3D G3DSA:1.10.150.20 183 244 2.1E-25 T 26-04-2017 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 ProSitePatterns PS00447 DNA polymerase family A signature. 756 775 - T 26-04-2017 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 168 1.3E-48 T 26-04-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 SUPERFAMILY SSF47807 169 285 1.64E-31 T 26-04-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 SMART SM00279 171 206 2.7E-13 T 26-04-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 PRINTS PR00868 DNA-polymerase family A (pol I) signature 702 725 4.7E-74 T 26-04-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 PRINTS PR00868 DNA-polymerase family A (pol I) signature 732 745 4.7E-74 T 26-04-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 PRINTS PR00868 DNA-polymerase family A (pol I) signature 793 804 4.7E-74 T 26-04-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 PRINTS PR00868 DNA-polymerase family A (pol I) signature 876 889 4.7E-74 T 26-04-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 PRINTS PR00868 DNA-polymerase family A (pol I) signature 756 781 4.7E-74 T 26-04-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 PRINTS PR00868 DNA-polymerase family A (pol I) signature 846 862 4.7E-74 T 26-04-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 PRINTS PR00868 DNA-polymerase family A (pol I) signature 680 695 4.7E-74 T 26-04-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 PRINTS PR00868 DNA-polymerase family A (pol I) signature 815 826 4.7E-74 T 26-04-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 PRINTS PR00868 DNA-polymerase family A (pol I) signature 657 679 4.7E-74 T 26-04-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 SUPERFAMILY SSF88723 2 168 1.85E-51 T 26-04-2017 IPR029060 PIN domain-like A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 Gene3D G3DSA:3.30.420.10 328 540 1.4E-38 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 Gene3D G3DSA:1.20.1060.10 541 665 9.3E-34 T 26-04-2017 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 TIGRFAM TIGR00593 pola: DNA polymerase I 6 929 5.6E-272 T 26-04-2017 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 Gene3D G3DSA:3.40.50.1010 4 182 6.5E-65 T 26-04-2017 IPR029060 PIN domain-like A4V04_RS04905 f4536e1a0d16f69e1f7dceb6db7efbb3 929 Pfam PF00476 DNA polymerase family A 549 926 8.0E-149 T 26-04-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4V04_RS07810 59c15ada5ad5a212ea9281265b5ca1f2 425 Pfam PF07687 Peptidase dimerisation domain 225 324 8.3E-5 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS07810 59c15ada5ad5a212ea9281265b5ca1f2 425 Gene3D G3DSA:3.40.630.10 15 233 2.0E-76 T 26-04-2017 A4V04_RS07810 59c15ada5ad5a212ea9281265b5ca1f2 425 Gene3D G3DSA:3.40.630.10 362 419 2.0E-76 T 26-04-2017 A4V04_RS07810 59c15ada5ad5a212ea9281265b5ca1f2 425 Pfam PF01546 Peptidase family M20/M25/M40 82 417 2.0E-25 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS07810 59c15ada5ad5a212ea9281265b5ca1f2 425 PIRSF PIRSF001235 5 421 6.8E-109 T 26-04-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 A4V04_RS07810 59c15ada5ad5a212ea9281265b5ca1f2 425 SUPERFAMILY SSF55031 225 339 6.93E-17 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS07810 59c15ada5ad5a212ea9281265b5ca1f2 425 Gene3D G3DSA:3.30.70.360 234 334 8.8E-25 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS07810 59c15ada5ad5a212ea9281265b5ca1f2 425 SUPERFAMILY SSF53187 347 419 2.36E-61 T 26-04-2017 A4V04_RS07810 59c15ada5ad5a212ea9281265b5ca1f2 425 SUPERFAMILY SSF53187 21 229 2.36E-61 T 26-04-2017 A4V04_RS07810 59c15ada5ad5a212ea9281265b5ca1f2 425 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 21 417 4.4E-87 T 26-04-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 A4V04_RS10545 bcad336c96da0151b9961f48b14ab9f3 641 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 630 1.7E-253 T 26-04-2017 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 A4V04_RS10545 bcad336c96da0151b9961f48b14ab9f3 641 Pfam PF13932 GidA associated domain 403 624 7.8E-68 T 26-04-2017 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 A4V04_RS10545 bcad336c96da0151b9961f48b14ab9f3 641 SMART SM01228 554 625 3.3E-35 T 26-04-2017 A4V04_RS10545 bcad336c96da0151b9961f48b14ab9f3 641 SUPERFAMILY SSF51905 6 67 4.33E-44 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10545 bcad336c96da0151b9961f48b14ab9f3 641 SUPERFAMILY SSF51905 98 263 4.33E-44 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10545 bcad336c96da0151b9961f48b14ab9f3 641 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 632 40.497 T 26-04-2017 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 A4V04_RS10545 bcad336c96da0151b9961f48b14ab9f3 641 Pfam PF01134 Glucose inhibited division protein A 9 400 8.6E-157 T 26-04-2017 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 A4V04_RS10545 bcad336c96da0151b9961f48b14ab9f3 641 Gene3D G3DSA:3.50.50.60 8 236 1.7E-36 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10545 bcad336c96da0151b9961f48b14ab9f3 641 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 275 289 - T 26-04-2017 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 A4V04_RS03240 2611a844b79e83ed3c19ab46366596f7 204 SUPERFAMILY SSF53335 18 136 9.56E-25 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS03240 2611a844b79e83ed3c19ab46366596f7 204 Gene3D G3DSA:3.40.50.150 22 138 1.9E-20 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS03240 2611a844b79e83ed3c19ab46366596f7 204 Pfam PF13489 Methyltransferase domain 20 128 8.7E-10 T 26-04-2017 A4V04_RS05855 286cd15616253dcda19694324f3ef3a1 363 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 137 165 - T 26-04-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A4V04_RS05855 286cd15616253dcda19694324f3ef3a1 363 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 13 345 34.249 T 26-04-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 A4V04_RS05855 286cd15616253dcda19694324f3ef3a1 363 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 33 347 3.7E-101 T 26-04-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 A4V04_RS05855 286cd15616253dcda19694324f3ef3a1 363 SUPERFAMILY SSF51161 45 332 1.62E-71 T 26-04-2017 IPR011004 Trimeric LpxA-like A4V04_RS05855 286cd15616253dcda19694324f3ef3a1 363 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 146 179 8.9E-8 T 26-04-2017 IPR001451 Hexapeptide repeat A4V04_RS05855 286cd15616253dcda19694324f3ef3a1 363 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 241 273 4.5E-7 T 26-04-2017 IPR001451 Hexapeptide repeat A4V04_RS05855 286cd15616253dcda19694324f3ef3a1 363 Gene3D G3DSA:2.160.10.10 119 152 1.3E-7 T 26-04-2017 A4V04_RS05855 286cd15616253dcda19694324f3ef3a1 363 Gene3D G3DSA:2.160.10.10 153 323 1.6E-43 T 26-04-2017 A4V04_RS05855 286cd15616253dcda19694324f3ef3a1 363 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 37 107 4.5E-18 T 26-04-2017 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 A4V04_RS04540 896549415c65addce0ff7ce76f0498a9 109 SUPERFAMILY SSF52833 3 108 1.9E-27 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS04540 896549415c65addce0ff7ce76f0498a9 109 Gene3D G3DSA:3.40.30.10 2 107 6.2E-26 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS04540 896549415c65addce0ff7ce76f0498a9 109 Pfam PF00085 Thioredoxin 4 105 3.8E-22 T 26-04-2017 IPR013766 Thioredoxin domain GO:0045454 A4V04_RS04540 896549415c65addce0ff7ce76f0498a9 109 PIRSF PIRSF000077 1 107 4.0E-21 T 26-04-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4V04_RS12785 8b2f9da8e86aeb262d62858408563135 178 ProSitePatterns PS01128 Shikimate kinase signature. 65 90 - T 26-04-2017 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4V04_RS12785 8b2f9da8e86aeb262d62858408563135 178 PRINTS PR01100 Shikimate kinase family signature 12 27 3.8E-19 T 26-04-2017 A4V04_RS12785 8b2f9da8e86aeb262d62858408563135 178 PRINTS PR01100 Shikimate kinase family signature 64 72 3.8E-19 T 26-04-2017 A4V04_RS12785 8b2f9da8e86aeb262d62858408563135 178 PRINTS PR01100 Shikimate kinase family signature 36 49 3.8E-19 T 26-04-2017 A4V04_RS12785 8b2f9da8e86aeb262d62858408563135 178 PRINTS PR01100 Shikimate kinase family signature 82 91 3.8E-19 T 26-04-2017 A4V04_RS12785 8b2f9da8e86aeb262d62858408563135 178 Pfam PF01202 Shikimate kinase 18 174 7.5E-46 T 26-04-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4V04_RS12785 8b2f9da8e86aeb262d62858408563135 178 Gene3D G3DSA:3.40.50.300 10 177 8.9E-53 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12785 8b2f9da8e86aeb262d62858408563135 178 SUPERFAMILY SSF52540 11 172 2.62E-27 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12785 8b2f9da8e86aeb262d62858408563135 178 Hamap MF_00109 Shikimate kinase [aroK]. 9 175 27.631 T 26-04-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4V04_RS10780 49c3e15fa95c5a3939ce65d58281c5ad 517 Pfam PF00890 FAD binding domain 32 484 1.3E-44 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10780 49c3e15fa95c5a3939ce65d58281c5ad 517 SUPERFAMILY SSF56425 293 451 4.88E-24 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10780 49c3e15fa95c5a3939ce65d58281c5ad 517 Gene3D G3DSA:3.90.700.10 294 439 5.3E-27 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10780 49c3e15fa95c5a3939ce65d58281c5ad 517 Gene3D G3DSA:3.50.50.60 447 512 3.2E-69 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10780 49c3e15fa95c5a3939ce65d58281c5ad 517 Gene3D G3DSA:3.50.50.60 26 264 3.2E-69 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10780 49c3e15fa95c5a3939ce65d58281c5ad 517 SUPERFAMILY SSF51905 450 514 9.42E-46 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10780 49c3e15fa95c5a3939ce65d58281c5ad 517 SUPERFAMILY SSF51905 27 270 9.42E-46 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08015 536026a4a4109b870dbe79b845fb695a 124 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 3.5E-25 T 26-04-2017 A4V04_RS08015 536026a4a4109b870dbe79b845fb695a 124 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 9.2E-33 T 26-04-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A4V04_RS08015 536026a4a4109b870dbe79b845fb695a 124 Gene3D G3DSA:3.30.460.10 2 106 2.2E-35 T 26-04-2017 A4V04_RS08015 536026a4a4109b870dbe79b845fb695a 124 SUPERFAMILY SSF81301 1 109 4.41E-35 T 26-04-2017 A4V04_RS08015 536026a4a4109b870dbe79b845fb695a 124 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 22.559 T 26-04-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A4V04_RS03655 45c3bcac010f1f2828c48e3aa0dfba72 188 Pfam PF00929 Exonuclease 16 177 1.8E-28 T 26-04-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III A4V04_RS03655 45c3bcac010f1f2828c48e3aa0dfba72 188 SMART SM00479 14 187 1.3E-15 T 26-04-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III A4V04_RS03655 45c3bcac010f1f2828c48e3aa0dfba72 188 SUPERFAMILY SSF53098 9 186 6.33E-43 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS03655 45c3bcac010f1f2828c48e3aa0dfba72 188 Gene3D G3DSA:3.30.420.10 11 187 5.3E-67 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS03655 45c3bcac010f1f2828c48e3aa0dfba72 188 Hamap MF_00045 Oligoribonuclease [orn]. 10 188 38.438 T 26-04-2017 IPR022894 Oligoribonuclease GO:0016788 A4V04_RS11000 112080cacee77f43979139ed229e184a 407 Pfam PF07690 Major Facilitator Superfamily 12 356 1.2E-45 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS11000 112080cacee77f43979139ed229e184a 407 SUPERFAMILY SSF103473 9 399 1.7E-57 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS11000 112080cacee77f43979139ed229e184a 407 PRINTS PR01035 Tetracycline resistance protein signature 164 184 4.9E-61 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS11000 112080cacee77f43979139ed229e184a 407 PRINTS PR01035 Tetracycline resistance protein signature 79 103 4.9E-61 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS11000 112080cacee77f43979139ed229e184a 407 PRINTS PR01035 Tetracycline resistance protein signature 136 158 4.9E-61 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS11000 112080cacee77f43979139ed229e184a 407 PRINTS PR01035 Tetracycline resistance protein signature 18 34 4.9E-61 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS11000 112080cacee77f43979139ed229e184a 407 PRINTS PR01035 Tetracycline resistance protein signature 106 127 4.9E-61 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS11000 112080cacee77f43979139ed229e184a 407 PRINTS PR01035 Tetracycline resistance protein signature 48 67 4.9E-61 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS11000 112080cacee77f43979139ed229e184a 407 PRINTS PR01035 Tetracycline resistance protein signature 340 363 4.9E-61 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS11000 112080cacee77f43979139ed229e184a 407 PRINTS PR01035 Tetracycline resistance protein signature 252 272 4.9E-61 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS11000 112080cacee77f43979139ed229e184a 407 PRINTS PR01035 Tetracycline resistance protein signature 280 301 4.9E-61 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS11000 112080cacee77f43979139ed229e184a 407 Gene3D G3DSA:1.20.1250.20 9 187 4.4E-34 T 26-04-2017 A4V04_RS11000 112080cacee77f43979139ed229e184a 407 Gene3D G3DSA:1.20.1250.20 214 396 1.3E-15 T 26-04-2017 A4V04_RS11000 112080cacee77f43979139ed229e184a 407 ProSitePatterns PS00216 Sugar transport proteins signature 1. 66 82 - T 26-04-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4V04_RS00070 f38eae1dd273668c22598c640b06aa69 229 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS00070 f38eae1dd273668c22598c640b06aa69 229 SMART SM00382 34 222 5.2E-15 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS00070 f38eae1dd273668c22598c640b06aa69 229 Gene3D G3DSA:3.40.50.300 6 224 2.8E-68 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00070 f38eae1dd273668c22598c640b06aa69 229 SUPERFAMILY SSF52540 7 225 5.19E-68 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00070 f38eae1dd273668c22598c640b06aa69 229 Pfam PF00005 ABC transporter 25 173 1.1E-31 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS05175 a3824c7940047914135e84ab0ef40689 204 Pfam PF02223 Thymidylate kinase 12 193 1.4E-48 T 26-04-2017 A4V04_RS05175 a3824c7940047914135e84ab0ef40689 204 Gene3D G3DSA:3.40.50.300 6 200 1.3E-65 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05175 a3824c7940047914135e84ab0ef40689 204 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 7 194 6.5E-52 T 26-04-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A4V04_RS05175 a3824c7940047914135e84ab0ef40689 204 SUPERFAMILY SSF52540 5 196 9.19E-52 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05175 a3824c7940047914135e84ab0ef40689 204 Hamap MF_00165 Thymidylate kinase [tmk]. 8 204 29.382 T 26-04-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A4V04_RS10035 b9c40bc63923f2679c1b165dc3e1f6b5 388 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 382 1.2E-6 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS10035 b9c40bc63923f2679c1b165dc3e1f6b5 388 SUPERFAMILY SSF161098 84 151 7.27E-30 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS10035 b9c40bc63923f2679c1b165dc3e1f6b5 388 SUPERFAMILY SSF161098 250 367 7.27E-30 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS10035 b9c40bc63923f2679c1b165dc3e1f6b5 388 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 81 149 4.2E-16 T 26-04-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A4V04_RS10035 b9c40bc63923f2679c1b165dc3e1f6b5 388 Gene3D G3DSA:1.10.3720.10 80 154 2.1E-38 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS10035 b9c40bc63923f2679c1b165dc3e1f6b5 388 Gene3D G3DSA:1.10.3720.10 253 382 2.1E-38 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS04050 3d2fd4de6de8e4aa254af7c9454e2dc4 186 Gene3D G3DSA:2.20.70.10 7 41 1.4E-18 T 26-04-2017 A4V04_RS04050 3d2fd4de6de8e4aa254af7c9454e2dc4 186 ProSitePatterns PS00893 Nudix box signature. 76 97 - T 26-04-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4V04_RS04050 3d2fd4de6de8e4aa254af7c9454e2dc4 186 SUPERFAMILY SSF55811 8 169 1.76E-36 T 26-04-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4V04_RS04050 3d2fd4de6de8e4aa254af7c9454e2dc4 186 Pfam PF14803 Nudix N-terminal 8 41 2.1E-17 T 26-04-2017 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 A4V04_RS04050 3d2fd4de6de8e4aa254af7c9454e2dc4 186 Gene3D G3DSA:3.90.79.10 43 177 1.9E-27 T 26-04-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4V04_RS04050 3d2fd4de6de8e4aa254af7c9454e2dc4 186 Pfam PF00293 NUDIX domain 44 150 4.6E-12 T 26-04-2017 IPR000086 NUDIX hydrolase domain GO:0016787 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 16 1372 10.387 T 26-04-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 Pfam PF04998 RNA polymerase Rpb1, domain 5 767 1316 1.4E-75 T 26-04-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 SMART SM00663 236 515 6.1E-176 T 26-04-2017 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 20 1367 0.0 T 26-04-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 Hamap MF_01323 DNA-directed RNA polymerase subunit gamma [rpoC1]. 14 589 32.073 T 26-04-2017 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 Pfam PF00623 RNA polymerase Rpb1, domain 2 345 397 2.3E-8 T 26-04-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 Pfam PF00623 RNA polymerase Rpb1, domain 2 390 486 3.3E-26 T 26-04-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 Gene3D G3DSA:2.40.50.100 1157 1209 2.8E-8 T 26-04-2017 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 Gene3D G3DSA:2.40.50.100 982 1020 1.3E-4 T 26-04-2017 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 Pfam PF04997 RNA polymerase Rpb1, domain 1 18 343 1.5E-88 T 26-04-2017 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 SUPERFAMILY SSF64484 18 945 0.0 T 26-04-2017 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 SUPERFAMILY SSF64484 1134 1363 0.0 T 26-04-2017 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 Pfam PF05000 RNA polymerase Rpb1, domain 4 675 764 4.6E-19 T 26-04-2017 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 Gene3D G3DSA:2.40.40.20 418 490 1.1E-35 T 26-04-2017 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 Gene3D G3DSA:2.40.40.20 350 377 1.1E-35 T 26-04-2017 A4V04_RS11155 46bdf2c4320c6bb878c7b5a36b35eb23 1372 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 645 9.4E-20 T 26-04-2017 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS02025 e03431c4c2cd31b7078e7818c46140e2 614 Pfam PF12532 Protein of unknown function (DUF3732) 376 578 1.7E-50 T 26-04-2017 IPR022205 Protein of unknown function DUF3732 A4V04_RS05390 bdc9de8cefb88fcd3fb4589cae2b2562 235 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 9 230 29.269 T 26-04-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4V04_RS05390 bdc9de8cefb88fcd3fb4589cae2b2562 235 Gene3D G3DSA:3.90.550.10 8 231 2.0E-66 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS05390 bdc9de8cefb88fcd3fb4589cae2b2562 235 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 12 227 1.7E-65 T 26-04-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4V04_RS05390 bdc9de8cefb88fcd3fb4589cae2b2562 235 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 11 228 2.0E-63 T 26-04-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4V04_RS05390 bdc9de8cefb88fcd3fb4589cae2b2562 235 SUPERFAMILY SSF53448 10 228 8.35E-55 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS05390 bdc9de8cefb88fcd3fb4589cae2b2562 235 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 106 113 - T 26-04-2017 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4V04_RS07660 3a081441de6ccf81a86d964ad45bc20b 865 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 755 863 1.8E-21 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07660 3a081441de6ccf81a86d964ad45bc20b 865 SUPERFAMILY SSF55874 699 863 1.23E-37 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07660 3a081441de6ccf81a86d964ad45bc20b 865 SMART SM00387 754 865 2.4E-30 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07660 3a081441de6ccf81a86d964ad45bc20b 865 Pfam PF00512 His Kinase A (phospho-acceptor) domain 642 710 4.2E-16 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS07660 3a081441de6ccf81a86d964ad45bc20b 865 PRINTS PR00344 Bacterial sensor protein C-terminal signature 827 845 8.1E-13 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS07660 3a081441de6ccf81a86d964ad45bc20b 865 PRINTS PR00344 Bacterial sensor protein C-terminal signature 851 864 8.1E-13 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS07660 3a081441de6ccf81a86d964ad45bc20b 865 PRINTS PR00344 Bacterial sensor protein C-terminal signature 792 806 8.1E-13 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS07660 3a081441de6ccf81a86d964ad45bc20b 865 PRINTS PR00344 Bacterial sensor protein C-terminal signature 810 820 8.1E-13 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS07660 3a081441de6ccf81a86d964ad45bc20b 865 SMART SM00388 642 710 7.1E-18 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS07660 3a081441de6ccf81a86d964ad45bc20b 865 Gene3D G3DSA:3.30.450.20 515 568 1.4E-5 T 26-04-2017 A4V04_RS07660 3a081441de6ccf81a86d964ad45bc20b 865 Gene3D G3DSA:3.30.565.10 696 864 4.8E-39 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07660 3a081441de6ccf81a86d964ad45bc20b 865 Gene3D G3DSA:1.10.287.130 638 695 3.4E-15 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS07660 3a081441de6ccf81a86d964ad45bc20b 865 SUPERFAMILY SSF47384 630 711 1.49E-17 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS09120 2fdbd54fe310a1ad168fdcb9df17640a 379 Gene3D G3DSA:3.40.50.300 89 352 8.2E-109 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09120 2fdbd54fe310a1ad168fdcb9df17640a 379 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 111 336 1.8E-105 T 26-04-2017 IPR022488 Polyphosphate kinase-2-related A4V04_RS09120 2fdbd54fe310a1ad168fdcb9df17640a 379 SUPERFAMILY SSF52540 142 323 6.29E-30 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09120 2fdbd54fe310a1ad168fdcb9df17640a 379 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 110 337 7.8E-116 T 26-04-2017 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 A4V04_RS11585 829711097248c634b14c927969135698 604 Gene3D G3DSA:3.40.50.300 341 594 5.8E-73 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11585 829711097248c634b14c927969135698 604 Gene3D G3DSA:3.40.50.300 1 253 6.5E-67 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11585 829711097248c634b14c927969135698 604 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS11585 829711097248c634b14c927969135698 604 SMART SM00382 30 229 2.2E-15 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS11585 829711097248c634b14c927969135698 604 SMART SM00382 374 570 1.1E-16 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS11585 829711097248c634b14c927969135698 604 ProSitePatterns PS00211 ABC transporters family signature. 493 507 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS11585 829711097248c634b14c927969135698 604 Pfam PF00005 ABC transporter 22 179 2.4E-25 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS11585 829711097248c634b14c927969135698 604 Pfam PF00005 ABC transporter 365 521 1.3E-28 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS11585 829711097248c634b14c927969135698 604 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 572 601 1.7E-5 T 26-04-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4V04_RS11585 829711097248c634b14c927969135698 604 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 295 2.5E-17 T 26-04-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4V04_RS11585 829711097248c634b14c927969135698 604 SUPERFAMILY SSF52540 346 592 7.59E-65 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11585 829711097248c634b14c927969135698 604 SUPERFAMILY SSF52540 1 250 3.62E-60 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11585 829711097248c634b14c927969135698 604 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 313 7.1E-22 T 26-04-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4V04_RS07115 a8e643962e2dc7a3f12556abd3a032c9 325 Pfam PF04015 Domain of unknown function (DUF362) 59 273 1.4E-30 T 26-04-2017 IPR007160 Domain of unknown function DUF362 A4V04_RS06700 6b390f3c8d948d9d94a36539c43d5f09 163 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 36 53 - T 26-04-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 A4V04_RS06700 6b390f3c8d948d9d94a36539c43d5f09 163 Gene3D G3DSA:2.40.100.10 2 162 2.5E-50 T 26-04-2017 IPR029000 Cyclophilin-like domain A4V04_RS06700 6b390f3c8d948d9d94a36539c43d5f09 163 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 2 161 3.3E-45 T 26-04-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4V04_RS06700 6b390f3c8d948d9d94a36539c43d5f09 163 PIRSF PIRSF001467 2 163 9.1E-26 T 26-04-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 A4V04_RS06700 6b390f3c8d948d9d94a36539c43d5f09 163 SUPERFAMILY SSF50891 2 162 1.36E-55 T 26-04-2017 IPR029000 Cyclophilin-like domain A4V04_RS06700 6b390f3c8d948d9d94a36539c43d5f09 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 41 53 1.9E-10 T 26-04-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4V04_RS06700 6b390f3c8d948d9d94a36539c43d5f09 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 15 30 1.9E-10 T 26-04-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4V04_RS06700 6b390f3c8d948d9d94a36539c43d5f09 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 133 1.9E-10 T 26-04-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4V04_RS11230 9e279e6cb9657717c4735d7c91d5b74b 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 19 203 8.4E-65 T 26-04-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11230 9e279e6cb9657717c4735d7c91d5b74b 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 206 28.88 T 26-04-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11230 9e279e6cb9657717c4735d7c91d5b74b 206 Pfam PF00573 Ribosomal protein L4/L1 family 19 203 4.4E-54 T 26-04-2017 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 A4V04_RS11230 9e279e6cb9657717c4735d7c91d5b74b 206 Gene3D G3DSA:3.40.1370.10 57 205 4.5E-49 T 26-04-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 A4V04_RS11230 9e279e6cb9657717c4735d7c91d5b74b 206 SUPERFAMILY SSF52166 1 205 3.79E-64 T 26-04-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 A4V04_RS04625 adf58a22e8699995dd1d8dd9f95f887c 313 PIRSF PIRSF017082 1 312 1.6E-74 T 26-04-2017 IPR005064 Bordetella uptake gene GO:0030288 A4V04_RS04625 adf58a22e8699995dd1d8dd9f95f887c 313 Gene3D G3DSA:3.40.190.10 120 216 1.6E-5 T 26-04-2017 A4V04_RS04625 adf58a22e8699995dd1d8dd9f95f887c 313 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 42 311 4.7E-47 T 26-04-2017 IPR005064 Bordetella uptake gene GO:0030288 A4V04_RS04625 adf58a22e8699995dd1d8dd9f95f887c 313 SUPERFAMILY SSF53850 108 279 3.0E-11 T 26-04-2017 A4V04_RS08435 16b2193bb3386f38e4d29065afd71038 147 Gene3D G3DSA:3.40.30.10 18 145 3.9E-23 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS08435 16b2193bb3386f38e4d29065afd71038 147 Pfam PF13098 Thioredoxin-like domain 21 129 7.7E-17 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS08435 16b2193bb3386f38e4d29065afd71038 147 SUPERFAMILY SSF52833 6 145 1.07E-20 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS10070 943f997777df16c72a9272baaf3c5779 559 Pfam PF00005 ABC transporter 383 513 1.8E-19 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS10070 943f997777df16c72a9272baaf3c5779 559 ProSitePatterns PS00211 ABC transporters family signature. 485 499 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS10070 943f997777df16c72a9272baaf3c5779 559 SMART SM00382 389 559 4.5E-12 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS10070 943f997777df16c72a9272baaf3c5779 559 Pfam PF06472 ABC transporter transmembrane region 2 12 287 1.5E-47 T 26-04-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4V04_RS10070 943f997777df16c72a9272baaf3c5779 559 SUPERFAMILY SSF90123 25 340 2.09E-20 T 26-04-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4V04_RS10070 943f997777df16c72a9272baaf3c5779 559 Gene3D G3DSA:3.40.50.300 383 557 6.3E-40 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10070 943f997777df16c72a9272baaf3c5779 559 Gene3D G3DSA:1.20.1560.10 20 339 1.5E-11 T 26-04-2017 A4V04_RS10070 943f997777df16c72a9272baaf3c5779 559 SUPERFAMILY SSF52540 383 557 1.13E-35 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05580 b6fdb736ac4d95364f70fa23cff68d19 87 Gene3D G3DSA:4.10.520.10 1 86 3.9E-30 T 26-04-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4V04_RS05580 b6fdb736ac4d95364f70fa23cff68d19 87 SMART SM00411 1 85 1.0E-30 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS05580 b6fdb736ac4d95364f70fa23cff68d19 87 SUPERFAMILY SSF47729 1 86 8.39E-28 T 26-04-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4V04_RS05580 b6fdb736ac4d95364f70fa23cff68d19 87 PRINTS PR01727 Prokaryotic integration host factor signature 69 83 1.7E-14 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS05580 b6fdb736ac4d95364f70fa23cff68d19 87 PRINTS PR01727 Prokaryotic integration host factor signature 35 50 1.7E-14 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS05580 b6fdb736ac4d95364f70fa23cff68d19 87 PRINTS PR01727 Prokaryotic integration host factor signature 53 66 1.7E-14 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS05580 b6fdb736ac4d95364f70fa23cff68d19 87 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 41 60 - T 26-04-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A4V04_RS05580 b6fdb736ac4d95364f70fa23cff68d19 87 Pfam PF00216 Bacterial DNA-binding protein 1 85 1.7E-27 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS13185 da34e6129d5e66424b213c0d37b6aa83 730 Gene3D G3DSA:3.40.50.220 1 108 1.0E-31 T 26-04-2017 IPR027464 Ornithine decarboxylase, N-terminal domain KEGG: 00330+4.1.1.17|KEGG: 00480+4.1.1.17|MetaCyc: PWY-46|MetaCyc: PWY-6305 A4V04_RS13185 da34e6129d5e66424b213c0d37b6aa83 730 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 109 551 8.8E-190 T 26-04-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 A4V04_RS13185 da34e6129d5e66424b213c0d37b6aa83 730 Gene3D G3DSA:3.90.100.10 594 723 6.4E-37 T 26-04-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A4V04_RS13185 da34e6129d5e66424b213c0d37b6aa83 730 SUPERFAMILY SSF52172 1 108 2.63E-25 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS13185 da34e6129d5e66424b213c0d37b6aa83 730 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 576 705 3.9E-46 T 26-04-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A4V04_RS13185 da34e6129d5e66424b213c0d37b6aa83 730 SUPERFAMILY SSF53383 109 568 5.59E-122 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS13185 da34e6129d5e66424b213c0d37b6aa83 730 Gene3D G3DSA:3.40.640.10 109 419 1.3E-112 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS13185 da34e6129d5e66424b213c0d37b6aa83 730 SUPERFAMILY SSF55904 572 723 3.66E-45 T 26-04-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A4V04_RS13185 da34e6129d5e66424b213c0d37b6aa83 730 PIRSF PIRSF009393 1 719 4.9E-282 T 26-04-2017 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 A4V04_RS13185 da34e6129d5e66424b213c0d37b6aa83 730 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 4 103 1.9E-16 T 26-04-2017 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 A4V04_RS13185 da34e6129d5e66424b213c0d37b6aa83 730 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 350 364 - T 26-04-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 A4V04_RS13185 da34e6129d5e66424b213c0d37b6aa83 730 Gene3D G3DSA:3.90.1150.10 421 593 2.2E-72 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS13185 da34e6129d5e66424b213c0d37b6aa83 730 TIGRFAM TIGR04301 ODC_inducible: ornithine decarboxylase SpeF 1 718 0.0 T 26-04-2017 IPR027568 Ornithine decarboxylase SpeF GO:0004586 KEGG: 00330+4.1.1.17|KEGG: 00480+4.1.1.17|MetaCyc: PWY-46|MetaCyc: PWY-6305 A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 SUPERFAMILY SSF55874 541 706 1.44E-41 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 Gene3D G3DSA:3.30.565.10 538 707 3.3E-44 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 595 707 3.8E-25 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 668 686 1.6E-17 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 692 705 1.6E-17 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 651 661 1.6E-17 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 633 647 1.6E-17 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 Gene3D G3DSA:3.30.450.20 380 433 3.4E-4 T 26-04-2017 A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 Gene3D G3DSA:3.30.450.20 173 283 5.0E-6 T 26-04-2017 A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 SUPERFAMILY SSF47384 473 551 5.3E-14 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 SMART SM00387 594 708 9.3E-35 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 Pfam PF00512 His Kinase A (phospho-acceptor) domain 487 551 9.1E-12 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 SMART SM00388 486 551 2.9E-13 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 Gene3D G3DSA:3.30.450.20 81 172 3.5E-5 T 26-04-2017 A4V04_RS07180 c9728eceb1d5cfb8e3b8b8a14492c178 710 Gene3D G3DSA:1.10.287.130 477 537 2.2E-11 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS01745 a1ad638521f935fad70af241fdfb12ec 462 Pfam PF03606 C4-dicarboxylate anaerobic carrier 3 459 4.2E-70 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS01745 a1ad638521f935fad70af241fdfb12ec 462 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 60 451 1.3E-96 T 26-04-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A4V04_RS03665 63af5722144e0cfff8f0e85f97956356 488 Gene3D G3DSA:3.40.50.1860 244 354 1.7E-34 T 26-04-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS03665 63af5722144e0cfff8f0e85f97956356 488 Pfam PF01177 Asp/Glu/Hydantoin racemase 248 474 1.2E-55 T 26-04-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS03665 63af5722144e0cfff8f0e85f97956356 488 Pfam PF01177 Asp/Glu/Hydantoin racemase 66 207 1.1E-6 T 26-04-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS03665 63af5722144e0cfff8f0e85f97956356 488 SUPERFAMILY SSF53681 244 354 1.33E-27 T 26-04-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS03665 63af5722144e0cfff8f0e85f97956356 488 Gene3D G3DSA:3.40.50.1860 355 466 1.8E-23 T 26-04-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS03665 63af5722144e0cfff8f0e85f97956356 488 TIGRFAM TIGR00035 asp_race: aspartate racemase 245 478 3.6E-53 T 26-04-2017 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A4V04_RS03665 63af5722144e0cfff8f0e85f97956356 488 SUPERFAMILY SSF53681 361 477 2.94E-19 T 26-04-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS03665 63af5722144e0cfff8f0e85f97956356 488 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 437 447 - T 26-04-2017 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS07620 76efe265e97710ba33a19ff16f3e58da 663 SMART SM00861 348 519 1.1E-71 T 26-04-2017 IPR005475 Transketolase-like, pyrimidine-binding domain A4V04_RS07620 76efe265e97710ba33a19ff16f3e58da 663 SUPERFAMILY SSF52518 2 323 2.49E-119 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS07620 76efe265e97710ba33a19ff16f3e58da 663 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 2 327 3.9E-158 T 26-04-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4V04_RS07620 76efe265e97710ba33a19ff16f3e58da 663 SUPERFAMILY SSF52518 337 520 1.62E-70 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS07620 76efe265e97710ba33a19ff16f3e58da 663 TIGRFAM TIGR00232 tktlase_bact: transketolase 2 660 2.4E-295 T 26-04-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 A4V04_RS07620 76efe265e97710ba33a19ff16f3e58da 663 ProSitePatterns PS00801 Transketolase signature 1. 6 26 - T 26-04-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4V04_RS07620 76efe265e97710ba33a19ff16f3e58da 663 Pfam PF02780 Transketolase, C-terminal domain 543 651 5.5E-11 T 26-04-2017 IPR033248 Transketolase, C-terminal domain A4V04_RS07620 76efe265e97710ba33a19ff16f3e58da 663 Gene3D G3DSA:3.40.50.970 1 315 3.4E-125 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS07620 76efe265e97710ba33a19ff16f3e58da 663 SUPERFAMILY SSF52922 526 661 8.64E-40 T 26-04-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4V04_RS07620 76efe265e97710ba33a19ff16f3e58da 663 Gene3D G3DSA:3.40.50.920 532 660 1.6E-41 T 26-04-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4V04_RS07620 76efe265e97710ba33a19ff16f3e58da 663 ProSitePatterns PS00802 Transketolase signature 2. 461 477 - T 26-04-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4V04_RS07620 76efe265e97710ba33a19ff16f3e58da 663 Gene3D G3DSA:3.40.50.970 320 526 6.6E-82 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS07620 76efe265e97710ba33a19ff16f3e58da 663 Pfam PF02779 Transketolase, pyrimidine binding domain 347 518 5.4E-49 T 26-04-2017 IPR005475 Transketolase-like, pyrimidine-binding domain A4V04_RS11870 768a6f6b4d436cedf6f4694277b718ff 165 Gene3D G3DSA:3.40.50.360 2 161 2.6E-16 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS11870 768a6f6b4d436cedf6f4694277b718ff 165 SUPERFAMILY SSF52218 1 88 1.26E-15 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS11870 768a6f6b4d436cedf6f4694277b718ff 165 Pfam PF12641 Flavodoxin domain 4 155 1.7E-34 T 26-04-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A4V04_RS12070 09ff9ceee58fe3fe4d52212b2cb2fd20 382 Gene3D G3DSA:2.40.160.20 231 351 6.6E-15 T 26-04-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A4V04_RS12070 09ff9ceee58fe3fe4d52212b2cb2fd20 382 Pfam PF13505 Outer membrane protein beta-barrel domain 218 349 1.8E-10 T 26-04-2017 IPR027385 Outer membrane protein beta-barrel A4V04_RS12070 09ff9ceee58fe3fe4d52212b2cb2fd20 382 SUPERFAMILY SSF56925 220 349 1.31E-12 T 26-04-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A4V04_RS12070 09ff9ceee58fe3fe4d52212b2cb2fd20 382 Gene3D G3DSA:2.40.160.20 47 194 5.0E-41 T 26-04-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A4V04_RS12070 09ff9ceee58fe3fe4d52212b2cb2fd20 382 ProDom PD103779 CRCA ANTIMICROBIAL RESISTANCE LIPOPROTEIN RCP A PEPTIDE ACYLATION LIPID EXPORTED 57 184 5.0E-18 T 26-04-2017 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 A4V04_RS12070 09ff9ceee58fe3fe4d52212b2cb2fd20 382 Pfam PF07017 Antimicrobial peptide resistance and lipid A acylation protein PagP 56 192 6.5E-43 T 26-04-2017 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 A4V04_RS12070 09ff9ceee58fe3fe4d52212b2cb2fd20 382 SUPERFAMILY SSF56925 46 196 4.0E-32 T 26-04-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A4V04_RS03515 0c9294785dd510711af6981bb8157d15 499 SUPERFAMILY SSF56235 2 260 1.89E-65 T 26-04-2017 IPR029055 Nucleophile aminohydrolases, N-terminal A4V04_RS03515 0c9294785dd510711af6981bb8157d15 499 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 468 7.2E-153 T 26-04-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A4V04_RS03515 0c9294785dd510711af6981bb8157d15 499 SUPERFAMILY SSF53271 253 485 3.07E-68 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS03515 0c9294785dd510711af6981bb8157d15 499 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 470 44.538 T 26-04-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A4V04_RS03515 0c9294785dd510711af6981bb8157d15 499 Pfam PF13522 Glutamine amidotransferase domain 66 211 1.5E-15 T 26-04-2017 A4V04_RS03515 0c9294785dd510711af6981bb8157d15 499 Gene3D G3DSA:3.40.50.2020 274 447 5.1E-46 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS03515 0c9294785dd510711af6981bb8157d15 499 Pfam PF00156 Phosphoribosyl transferase domain 278 395 2.5E-9 T 26-04-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4V04_RS03515 0c9294785dd510711af6981bb8157d15 499 PIRSF PIRSF000485 1 484 1.6E-156 T 26-04-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A4V04_RS03515 0c9294785dd510711af6981bb8157d15 499 Gene3D G3DSA:3.60.20.10 2 260 1.0E-58 T 26-04-2017 IPR029055 Nucleophile aminohydrolases, N-terminal A4V04_RS04320 5d023b81882cf55e583961b884c92a4d 407 Pfam PF12146 Serine aminopeptidase, S33 76 201 9.9E-16 T 26-04-2017 IPR022742 Serine aminopeptidase, S33 A4V04_RS04320 5d023b81882cf55e583961b884c92a4d 407 Gene3D G3DSA:3.40.50.1820 70 281 3.0E-37 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS04320 5d023b81882cf55e583961b884c92a4d 407 SUPERFAMILY SSF53474 72 280 1.65E-27 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS10135 a5c998b274ec0ee087aa2d5f662bc217 600 SUPERFAMILY SSF55486 51 574 5.13E-23 T 26-04-2017 A4V04_RS10770 f0ac9a3d4f52907076e540b87f4e0fe5 608 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 608 7.1E-242 T 26-04-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A4V04_RS10770 f0ac9a3d4f52907076e540b87f4e0fe5 608 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 608 38.395 T 26-04-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A4V04_RS10770 f0ac9a3d4f52907076e540b87f4e0fe5 608 SUPERFAMILY SSF53697 247 608 2.97E-107 T 26-04-2017 A4V04_RS10770 f0ac9a3d4f52907076e540b87f4e0fe5 608 Gene3D G3DSA:3.40.50.10490 245 441 9.2E-70 T 26-04-2017 A4V04_RS10770 f0ac9a3d4f52907076e540b87f4e0fe5 608 Gene3D G3DSA:3.40.50.10490 442 608 1.8E-63 T 26-04-2017 A4V04_RS10770 f0ac9a3d4f52907076e540b87f4e0fe5 608 SUPERFAMILY SSF56235 2 229 6.69E-70 T 26-04-2017 IPR029055 Nucleophile aminohydrolases, N-terminal A4V04_RS10770 f0ac9a3d4f52907076e540b87f4e0fe5 608 Pfam PF13522 Glutamine amidotransferase domain 67 185 6.0E-20 T 26-04-2017 A4V04_RS10770 f0ac9a3d4f52907076e540b87f4e0fe5 608 Gene3D G3DSA:3.60.20.10 2 228 1.3E-73 T 26-04-2017 IPR029055 Nucleophile aminohydrolases, N-terminal A4V04_RS10770 f0ac9a3d4f52907076e540b87f4e0fe5 608 Pfam PF01380 SIS domain 461 590 1.6E-23 T 26-04-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4V04_RS10770 f0ac9a3d4f52907076e540b87f4e0fe5 608 Pfam PF01380 SIS domain 291 416 3.1E-28 T 26-04-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4V04_RS03610 9f764c6cd190ce3eb5e8513faf26eb3c 86 Pfam PF00886 Ribosomal protein S16 8 68 7.3E-22 T 26-04-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS03610 9f764c6cd190ce3eb5e8513faf26eb3c 86 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 79 9.1E-27 T 26-04-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS03610 9f764c6cd190ce3eb5e8513faf26eb3c 86 Gene3D G3DSA:3.30.1320.10 1 78 2.0E-29 T 26-04-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS03610 9f764c6cd190ce3eb5e8513faf26eb3c 86 SUPERFAMILY SSF54565 1 78 3.01E-26 T 26-04-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS03610 9f764c6cd190ce3eb5e8513faf26eb3c 86 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 22.288 T 26-04-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS12550 a2f676cf2854b712b5d0a1bc3cd27163 553 SMART SM00382 31 235 1.1E-8 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS12550 a2f676cf2854b712b5d0a1bc3cd27163 553 SMART SM00382 347 525 2.5E-7 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS12550 a2f676cf2854b712b5d0a1bc3cd27163 553 Pfam PF00005 ABC transporter 22 190 2.5E-29 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS12550 a2f676cf2854b712b5d0a1bc3cd27163 553 Pfam PF00005 ABC transporter 339 472 1.7E-24 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS12550 a2f676cf2854b712b5d0a1bc3cd27163 553 SUPERFAMILY SSF52540 18 241 7.91E-48 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12550 a2f676cf2854b712b5d0a1bc3cd27163 553 Gene3D G3DSA:3.40.50.300 140 287 7.9E-52 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12550 a2f676cf2854b712b5d0a1bc3cd27163 553 Gene3D G3DSA:3.40.50.300 12 105 7.9E-52 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12550 a2f676cf2854b712b5d0a1bc3cd27163 553 Pfam PF12848 ABC transporter 229 305 6.0E-11 T 26-04-2017 IPR032781 ABC-transporter extension domain A4V04_RS12550 a2f676cf2854b712b5d0a1bc3cd27163 553 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 551 3.5E-288 T 26-04-2017 IPR022374 ABC transporter, ATP-binding protein, ChvD A4V04_RS12550 a2f676cf2854b712b5d0a1bc3cd27163 553 Gene3D G3DSA:3.40.50.300 321 533 7.3E-47 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12550 a2f676cf2854b712b5d0a1bc3cd27163 553 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS12550 a2f676cf2854b712b5d0a1bc3cd27163 553 SUPERFAMILY SSF52540 301 521 7.48E-47 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09680 203e724025bc01426c1a03dbff8192ec 478 ProSitePatterns PS00163 Fumarate lyases signature. 316 325 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS09680 203e724025bc01426c1a03dbff8192ec 478 PRINTS PR00149 Fumarate lyase superfamily signature 270 297 1.5E-26 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09680 203e724025bc01426c1a03dbff8192ec 478 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 1.5E-26 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09680 203e724025bc01426c1a03dbff8192ec 478 PRINTS PR00149 Fumarate lyase superfamily signature 316 332 1.5E-26 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09680 203e724025bc01426c1a03dbff8192ec 478 PRINTS PR00149 Fumarate lyase superfamily signature 179 197 1.5E-26 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09680 203e724025bc01426c1a03dbff8192ec 478 Gene3D G3DSA:1.10.40.30 409 463 2.5E-8 T 26-04-2017 A4V04_RS09680 203e724025bc01426c1a03dbff8192ec 478 Pfam PF00206 Lyase 11 341 5.8E-87 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS09680 203e724025bc01426c1a03dbff8192ec 478 Gene3D G3DSA:1.10.275.10 2 138 1.2E-46 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS09680 203e724025bc01426c1a03dbff8192ec 478 PRINTS PR00145 Argininosuccinate lyase family signature 174 194 3.4E-6 T 26-04-2017 A4V04_RS09680 203e724025bc01426c1a03dbff8192ec 478 PRINTS PR00145 Argininosuccinate lyase family signature 316 332 3.4E-6 T 26-04-2017 A4V04_RS09680 203e724025bc01426c1a03dbff8192ec 478 PRINTS PR00145 Argininosuccinate lyase family signature 133 155 3.4E-6 T 26-04-2017 A4V04_RS09680 203e724025bc01426c1a03dbff8192ec 478 Gene3D G3DSA:1.20.200.10 139 401 4.4E-82 T 26-04-2017 A4V04_RS09680 203e724025bc01426c1a03dbff8192ec 478 Pfam PF10415 Fumarase C C-terminus 409 459 1.7E-8 T 26-04-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS09680 203e724025bc01426c1a03dbff8192ec 478 SUPERFAMILY SSF48557 3 456 1.46E-123 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS03085 482f172ec09c10aee847ac837ce6277a 353 SUPERFAMILY SSF56425 160 294 3.66E-28 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03085 482f172ec09c10aee847ac837ce6277a 353 SUPERFAMILY SSF51905 29 155 1.74E-26 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03085 482f172ec09c10aee847ac837ce6277a 353 SUPERFAMILY SSF51905 294 351 1.74E-26 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03085 482f172ec09c10aee847ac837ce6277a 353 Gene3D G3DSA:3.50.50.60 291 351 1.7E-53 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03085 482f172ec09c10aee847ac837ce6277a 353 Gene3D G3DSA:3.50.50.60 3 138 1.7E-53 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03085 482f172ec09c10aee847ac837ce6277a 353 Pfam PF00890 FAD binding domain 30 334 3.2E-40 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03085 482f172ec09c10aee847ac837ce6277a 353 Gene3D G3DSA:3.90.700.10 162 284 1.2E-27 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03085 482f172ec09c10aee847ac837ce6277a 353 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 5 347 1.3E-87 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS02345 ae837b2578675660d70cf9bce53a71d4 563 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 290 563 1.1E-54 T 26-04-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 A4V04_RS02345 ae837b2578675660d70cf9bce53a71d4 563 SMART SM00869 308 552 1.8E-37 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02345 ae837b2578675660d70cf9bce53a71d4 563 Gene3D G3DSA:2.40.128.130 288 563 6.8E-72 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02345 ae837b2578675660d70cf9bce53a71d4 563 PRINTS PR01484 Pertactin virulence factor family signature 450 473 4.0E-16 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02345 ae837b2578675660d70cf9bce53a71d4 563 PRINTS PR01484 Pertactin virulence factor family signature 288 306 4.0E-16 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02345 ae837b2578675660d70cf9bce53a71d4 563 PRINTS PR01484 Pertactin virulence factor family signature 308 328 4.0E-16 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02345 ae837b2578675660d70cf9bce53a71d4 563 PRINTS PR01484 Pertactin virulence factor family signature 431 448 4.0E-16 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02345 ae837b2578675660d70cf9bce53a71d4 563 PRINTS PR01484 Pertactin virulence factor family signature 518 543 4.0E-16 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02345 ae837b2578675660d70cf9bce53a71d4 563 PRINTS PR01484 Pertactin virulence factor family signature 543 563 4.0E-16 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02345 ae837b2578675660d70cf9bce53a71d4 563 Pfam PF03797 Autotransporter beta-domain 309 543 9.4E-42 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02345 ae837b2578675660d70cf9bce53a71d4 563 SUPERFAMILY SSF103515 285 563 1.7E-49 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS05105 240181726e2580029bc19cc7084b6e1c 430 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 24 425 1.3E-118 T 26-04-2017 IPR004681 TRAP transporter permease protein GO:0016021 A4V04_RS05105 240181726e2580029bc19cc7084b6e1c 430 PIRSF PIRSF006066 8 430 5.8E-126 T 26-04-2017 IPR004681 TRAP transporter permease protein GO:0016021 A4V04_RS05105 240181726e2580029bc19cc7084b6e1c 430 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 14 420 3.5E-101 T 26-04-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A4V04_RS05395 420fa03d4452f0885119c91e0f7ee73e 161 Pfam PF02542 YgbB family 6 159 3.6E-65 T 26-04-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4V04_RS05395 420fa03d4452f0885119c91e0f7ee73e 161 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 6 160 3.8E-68 T 26-04-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4V04_RS05395 420fa03d4452f0885119c91e0f7ee73e 161 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 5 160 36.357 T 26-04-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4V04_RS05395 420fa03d4452f0885119c91e0f7ee73e 161 SUPERFAMILY SSF69765 4 160 2.09E-65 T 26-04-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4V04_RS05395 420fa03d4452f0885119c91e0f7ee73e 161 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 39 54 - T 26-04-2017 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4V04_RS05395 420fa03d4452f0885119c91e0f7ee73e 161 Gene3D G3DSA:3.30.1330.50 3 160 3.6E-70 T 26-04-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4V04_RS06325 a23d4bff57cfc6d6e77825a0a44c7fc3 116 Pfam PF04221 RelB antitoxin 16 83 9.9E-13 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS06325 a23d4bff57cfc6d6e77825a0a44c7fc3 116 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 17 80 7.5E-17 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS10495 cdffd0ff353925cb6c41016a865e7cd0 103 Pfam PF01809 Haemolytic domain 3 69 2.6E-25 T 26-04-2017 IPR002696 Putative membrane protein insertion efficiency factor A4V04_RS10495 cdffd0ff353925cb6c41016a865e7cd0 103 SMART SM01234 2 69 1.6E-32 T 26-04-2017 IPR002696 Putative membrane protein insertion efficiency factor A4V04_RS10495 cdffd0ff353925cb6c41016a865e7cd0 103 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 2 70 22.064 T 26-04-2017 IPR002696 Putative membrane protein insertion efficiency factor A4V04_RS10495 cdffd0ff353925cb6c41016a865e7cd0 103 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 6 74 1.3E-25 T 26-04-2017 IPR002696 Putative membrane protein insertion efficiency factor A4V04_RS10495 cdffd0ff353925cb6c41016a865e7cd0 103 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 69 5.0E-15 T 26-04-2017 IPR002696 Putative membrane protein insertion efficiency factor A4V04_RS07520 14c5264ccd5e37487e7be85b0a96a8a7 214 Gene3D G3DSA:3.30.70.20 109 149 3.2E-7 T 26-04-2017 A4V04_RS07520 14c5264ccd5e37487e7be85b0a96a8a7 214 Pfam PF00037 4Fe-4S binding domain 168 186 5.0E-7 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07520 14c5264ccd5e37487e7be85b0a96a8a7 214 Gene3D G3DSA:3.30.70.20 150 187 3.3E-12 T 26-04-2017 A4V04_RS07520 14c5264ccd5e37487e7be85b0a96a8a7 214 Gene3D G3DSA:1.10.1060.10 46 108 7.2E-13 T 26-04-2017 A4V04_RS07520 14c5264ccd5e37487e7be85b0a96a8a7 214 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 66 77 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS07520 14c5264ccd5e37487e7be85b0a96a8a7 214 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 105 116 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS07520 14c5264ccd5e37487e7be85b0a96a8a7 214 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 174 185 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS07520 14c5264ccd5e37487e7be85b0a96a8a7 214 SUPERFAMILY SSF54862 63 189 1.07E-21 T 26-04-2017 A4V04_RS07520 14c5264ccd5e37487e7be85b0a96a8a7 214 Pfam PF12838 4Fe-4S dicluster domain 65 119 1.5E-9 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS11385 41342132caa1847e785dfdf6c67711a6 205 SUPERFAMILY SSF89155 16 200 4.19E-22 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS11385 41342132caa1847e785dfdf6c67711a6 205 Gene3D G3DSA:1.10.3480.10 68 201 4.8E-19 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS11385 41342132caa1847e785dfdf6c67711a6 205 Pfam PF02613 Nitrate reductase delta subunit 67 162 1.0E-12 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS07735 0b2a657505e6d46869c3346add2174f9 299 PIRSF PIRSF000401 1 299 2.0E-88 T 26-04-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A4V04_RS07735 0b2a657505e6d46869c3346add2174f9 299 SUPERFAMILY SSF53335 95 274 1.11E-37 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS07735 0b2a657505e6d46869c3346add2174f9 299 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 4 299 7.8E-85 T 26-04-2017 A4V04_RS07735 0b2a657505e6d46869c3346add2174f9 299 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 4 276 1.6E-68 T 26-04-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A4V04_RS07735 0b2a657505e6d46869c3346add2174f9 299 Gene3D G3DSA:3.40.50.150 107 293 6.2E-41 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS07735 0b2a657505e6d46869c3346add2174f9 299 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 2 298 31.63 T 26-04-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A4V04_RS10970 2443ca1b8aefd76c6d4483450b2b08e9 93 Gene3D G3DSA:3.40.630.10 6 85 1.2E-6 T 26-04-2017 A4V04_RS10970 2443ca1b8aefd76c6d4483450b2b08e9 93 SUPERFAMILY SSF53187 5 85 5.02E-5 T 26-04-2017 A4V04_RS08765 4b1c99750f145e61591fbbc6f82c3f1a 169 SUPERFAMILY SSF52374 29 158 6.52E-23 T 26-04-2017 A4V04_RS08765 4b1c99750f145e61591fbbc6f82c3f1a 169 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 22 162 1.4E-59 T 26-04-2017 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 A4V04_RS08765 4b1c99750f145e61591fbbc6f82c3f1a 169 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 31 97 3.8E-13 T 26-04-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4V04_RS08765 4b1c99750f145e61591fbbc6f82c3f1a 169 Gene3D G3DSA:3.40.50.620 30 149 1.5E-33 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS08765 4b1c99750f145e61591fbbc6f82c3f1a 169 Pfam PF01467 Cytidylyltransferase-like 33 126 4.8E-15 T 26-04-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4V04_RS05210 2804480f7ca0fa4db89570ddc6667d49 203 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 14 199 2.0E-30 T 26-04-2017 IPR013343 CRISPR-associated protein Cas4 A4V04_RS05210 2804480f7ca0fa4db89570ddc6667d49 203 Pfam PF01930 Domain of unknown function DUF83 16 200 2.7E-17 T 26-04-2017 IPR022765 Dna2/Cas4, domain of unknown function DUF83 A4V04_RS00330 851c1333441a3589bc77f4d062f46d73 171 Gene3D G3DSA:3.40.50.300 1 165 3.8E-50 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00330 851c1333441a3589bc77f4d062f46d73 171 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 3 137 2.3E-41 T 26-04-2017 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A4V04_RS00330 851c1333441a3589bc77f4d062f46d73 171 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 3 162 3.4E-40 T 26-04-2017 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A4V04_RS00330 851c1333441a3589bc77f4d062f46d73 171 SUPERFAMILY SSF52540 1 165 4.07E-21 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06115 185037e3fadd4d63d0dc9ba3b1620e56 329 Gene3D G3DSA:3.60.21.10 30 225 4.0E-14 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS06115 185037e3fadd4d63d0dc9ba3b1620e56 329 Pfam PF00149 Calcineurin-like phosphoesterase 33 222 2.6E-15 T 26-04-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4V04_RS06115 185037e3fadd4d63d0dc9ba3b1620e56 329 SUPERFAMILY SSF56300 33 234 4.43E-20 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS09565 c29cd5a796dd889a26e6283726109081 193 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 124 130 - T 26-04-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4V04_RS09565 c29cd5a796dd889a26e6283726109081 193 PIRSF PIRSF004553 6 190 1.5E-35 T 26-04-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS09565 c29cd5a796dd889a26e6283726109081 193 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 188 3.3E-36 T 26-04-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS09565 c29cd5a796dd889a26e6283726109081 193 SUPERFAMILY SSF53335 7 175 2.49E-36 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS09565 c29cd5a796dd889a26e6283726109081 193 Pfam PF03602 Conserved hypothetical protein 95 7 185 3.2E-41 T 26-04-2017 A4V04_RS09565 c29cd5a796dd889a26e6283726109081 193 Gene3D G3DSA:3.40.50.150 4 191 1.8E-46 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS02935 f414a2ee5ad8006c808165d323d04773 356 Gene3D G3DSA:3.20.20.300 10 298 3.1E-86 T 26-04-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4V04_RS02935 f414a2ee5ad8006c808165d323d04773 356 SUPERFAMILY SSF51445 10 304 7.48E-79 T 26-04-2017 IPR017853 Glycoside hydrolase superfamily A4V04_RS02935 f414a2ee5ad8006c808165d323d04773 356 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 11 312 3.1E-73 T 26-04-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4V04_RS02935 f414a2ee5ad8006c808165d323d04773 356 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 10 345 48.727 T 26-04-2017 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 A4V04_RS10125 6175aec4097da8624964076077c5f5ac 428 Pfam PF03606 C4-dicarboxylate anaerobic carrier 51 427 4.6E-21 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS10125 6175aec4097da8624964076077c5f5ac 428 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 58 416 5.7E-56 T 26-04-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A4V04_RS09395 7a41947ac856c712bff5e7532e538103 68 Gene3D G3DSA:3.30.70.100 1 60 3.6E-10 T 26-04-2017 A4V04_RS09395 7a41947ac856c712bff5e7532e538103 68 Pfam PF00403 Heavy-metal-associated domain 5 58 1.0E-6 T 26-04-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4V04_RS09395 7a41947ac856c712bff5e7532e538103 68 SUPERFAMILY SSF55008 1 60 1.23E-9 T 26-04-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4V04_RS12560 970e327f51fd2258ac75ab1481332c07 258 Pfam PF00902 Sec-independent protein translocase protein (TatC) 22 231 4.9E-64 T 26-04-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4V04_RS12560 970e327f51fd2258ac75ab1481332c07 258 ProSitePatterns PS01218 TatC family signature. 164 183 - T 26-04-2017 IPR019820 Sec-independent periplasmic protein translocase, conserved site A4V04_RS12560 970e327f51fd2258ac75ab1481332c07 258 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 164 192 4.4E-44 T 26-04-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4V04_RS12560 970e327f51fd2258ac75ab1481332c07 258 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 113 139 4.4E-44 T 26-04-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4V04_RS12560 970e327f51fd2258ac75ab1481332c07 258 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 18 45 4.4E-44 T 26-04-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4V04_RS12560 970e327f51fd2258ac75ab1481332c07 258 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 95 113 4.4E-44 T 26-04-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4V04_RS12560 970e327f51fd2258ac75ab1481332c07 258 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 19 236 1.9E-67 T 26-04-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4V04_RS12560 970e327f51fd2258ac75ab1481332c07 258 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 12 251 18.113 T 26-04-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4V04_RS03580 01407fd77861bfa3dc188abcda323cec 256 SUPERFAMILY SSF56300 157 229 2.28E-19 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS03580 01407fd77861bfa3dc188abcda323cec 256 SUPERFAMILY SSF56300 4 127 2.28E-19 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS03580 01407fd77861bfa3dc188abcda323cec 256 Pfam PF00149 Calcineurin-like phosphoesterase 4 223 2.8E-14 T 26-04-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4V04_RS03580 01407fd77861bfa3dc188abcda323cec 256 Gene3D G3DSA:3.60.21.10 6 84 1.5E-14 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS03580 01407fd77861bfa3dc188abcda323cec 256 Gene3D G3DSA:3.60.21.10 159 245 1.5E-14 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS10665 5a4c2738abb877c82d7b4b6d091aa2f2 182 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 179 1.4E-29 T 26-04-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 A4V04_RS10665 5a4c2738abb877c82d7b4b6d091aa2f2 182 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 180 1.1E-37 T 26-04-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 A4V04_RS10665 5a4c2738abb877c82d7b4b6d091aa2f2 182 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 182 17.274 T 26-04-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 A4V04_RS10665 5a4c2738abb877c82d7b4b6d091aa2f2 182 SUPERFAMILY SSF47928 3 108 1.27E-16 T 26-04-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 A4V04_RS10665 5a4c2738abb877c82d7b4b6d091aa2f2 182 PRINTS PR00125 ATP synthase delta subunit signature 155 173 4.3E-20 T 26-04-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 A4V04_RS10665 5a4c2738abb877c82d7b4b6d091aa2f2 182 PRINTS PR00125 ATP synthase delta subunit signature 89 103 4.3E-20 T 26-04-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 A4V04_RS10665 5a4c2738abb877c82d7b4b6d091aa2f2 182 PRINTS PR00125 ATP synthase delta subunit signature 140 155 4.3E-20 T 26-04-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 A4V04_RS10665 5a4c2738abb877c82d7b4b6d091aa2f2 182 PRINTS PR00125 ATP synthase delta subunit signature 7 26 4.3E-20 T 26-04-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 A4V04_RS10665 5a4c2738abb877c82d7b4b6d091aa2f2 182 PRINTS PR00125 ATP synthase delta subunit signature 78 89 4.3E-20 T 26-04-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 A4V04_RS10665 5a4c2738abb877c82d7b4b6d091aa2f2 182 Gene3D G3DSA:1.10.520.20 2 108 1.7E-19 T 26-04-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 A4V04_RS08255 d81fc63f7253d005ab7ecabd7c572e6a 197 Pfam PF01553 Acyltransferase 24 143 3.8E-18 T 26-04-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4V04_RS08255 d81fc63f7253d005ab7ecabd7c572e6a 197 Gene3D G3DSA:3.40.1130.10 25 189 1.8E-21 T 26-04-2017 A4V04_RS08255 d81fc63f7253d005ab7ecabd7c572e6a 197 SMART SM00563 28 147 7.4E-14 T 26-04-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4V04_RS08255 d81fc63f7253d005ab7ecabd7c572e6a 197 SUPERFAMILY SSF69593 15 196 3.66E-32 T 26-04-2017 A4V04_RS07205 1440701550873c52bc670848ce040d99 417 SMART SM00852 8 158 5.4E-24 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS07205 1440701550873c52bc670848ce040d99 417 SUPERFAMILY SSF53474 200 416 2.1E-41 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS07205 1440701550873c52bc670848ce040d99 417 Pfam PF02230 Phospholipase/Carboxylesterase 200 415 6.6E-51 T 26-04-2017 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 A4V04_RS07205 1440701550873c52bc670848ce040d99 417 Pfam PF00994 Probable molybdopterin binding domain 9 151 9.6E-28 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS07205 1440701550873c52bc670848ce040d99 417 SUPERFAMILY SSF53218 5 189 3.01E-39 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS07205 1440701550873c52bc670848ce040d99 417 Gene3D G3DSA:3.40.980.10 3 150 9.6E-45 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS07205 1440701550873c52bc670848ce040d99 417 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 70 83 - T 26-04-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 A4V04_RS07205 1440701550873c52bc670848ce040d99 417 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 6 150 9.0E-36 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS07205 1440701550873c52bc670848ce040d99 417 Gene3D G3DSA:3.40.50.1820 199 415 9.6E-58 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS12335 667cdac9228815731bd9e67981021551 565 Gene3D G3DSA:3.30.300.30 465 561 1.4E-30 T 26-04-2017 A4V04_RS12335 667cdac9228815731bd9e67981021551 565 SUPERFAMILY SSF56801 19 563 2.09E-141 T 26-04-2017 A4V04_RS12335 667cdac9228815731bd9e67981021551 565 Gene3D G3DSA:3.40.50.980 221 381 1.7E-40 T 26-04-2017 A4V04_RS12335 667cdac9228815731bd9e67981021551 565 Pfam PF00501 AMP-binding enzyme 35 470 2.2E-102 T 26-04-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4V04_RS12335 667cdac9228815731bd9e67981021551 565 Gene3D G3DSA:2.30.38.10 382 461 1.3E-24 T 26-04-2017 A4V04_RS12335 667cdac9228815731bd9e67981021551 565 ProSitePatterns PS00455 Putative AMP-binding domain signature. 215 226 - T 26-04-2017 IPR020845 AMP-binding, conserved site A4V04_RS12335 667cdac9228815731bd9e67981021551 565 Pfam PF13193 AMP-binding enzyme C-terminal domain 479 553 1.3E-19 T 26-04-2017 IPR025110 AMP-binding enzyme C-terminal domain A4V04_RS12335 667cdac9228815731bd9e67981021551 565 Gene3D G3DSA:3.40.50.980 29 155 1.3E-39 T 26-04-2017 A4V04_RS12335 667cdac9228815731bd9e67981021551 565 Gene3D G3DSA:3.40.50.980 189 220 1.3E-39 T 26-04-2017 A4V04_RS08240 eb3bb7f1029f2bd8817bf00987fc468f 517 Gene3D G3DSA:3.90.700.10 301 443 8.9E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08240 eb3bb7f1029f2bd8817bf00987fc468f 517 Pfam PF00890 FAD binding domain 30 488 8.3E-47 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08240 eb3bb7f1029f2bd8817bf00987fc468f 517 SUPERFAMILY SSF51905 454 514 1.08E-43 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08240 eb3bb7f1029f2bd8817bf00987fc468f 517 SUPERFAMILY SSF51905 22 284 1.08E-43 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08240 eb3bb7f1029f2bd8817bf00987fc468f 517 Gene3D G3DSA:3.50.50.60 25 267 6.2E-68 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08240 eb3bb7f1029f2bd8817bf00987fc468f 517 Gene3D G3DSA:3.50.50.60 451 515 6.2E-68 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08240 eb3bb7f1029f2bd8817bf00987fc468f 517 SUPERFAMILY SSF56425 302 455 1.36E-24 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS07880 14d3ec8c1ff7f2d84b74db20cdb0f64a 605 Gene3D G3DSA:3.40.190.10 147 224 7.6E-9 T 26-04-2017 A4V04_RS07880 14d3ec8c1ff7f2d84b74db20cdb0f64a 605 SUPERFAMILY SSF55874 436 600 2.23E-27 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07880 14d3ec8c1ff7f2d84b74db20cdb0f64a 605 SMART SM00387 490 598 6.1E-17 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07880 14d3ec8c1ff7f2d84b74db20cdb0f64a 605 Pfam PF00512 His Kinase A (phospho-acceptor) domain 385 448 4.1E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS07880 14d3ec8c1ff7f2d84b74db20cdb0f64a 605 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 73 281 3.9E-23 T 26-04-2017 A4V04_RS07880 14d3ec8c1ff7f2d84b74db20cdb0f64a 605 SUPERFAMILY SSF53850 37 290 1.09E-12 T 26-04-2017 A4V04_RS07880 14d3ec8c1ff7f2d84b74db20cdb0f64a 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 543 2.6E-6 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS07880 14d3ec8c1ff7f2d84b74db20cdb0f64a 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 558 576 2.6E-6 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS07880 14d3ec8c1ff7f2d84b74db20cdb0f64a 605 Gene3D G3DSA:1.10.287.130 383 439 4.7E-6 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS07880 14d3ec8c1ff7f2d84b74db20cdb0f64a 605 Gene3D G3DSA:3.30.565.10 451 602 4.3E-26 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07880 14d3ec8c1ff7f2d84b74db20cdb0f64a 605 SUPERFAMILY SSF47384 376 448 7.26E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS07880 14d3ec8c1ff7f2d84b74db20cdb0f64a 605 Gene3D G3DSA:3.40.190.10 74 146 2.1E-4 T 26-04-2017 A4V04_RS07880 14d3ec8c1ff7f2d84b74db20cdb0f64a 605 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 495 596 1.1E-11 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07880 14d3ec8c1ff7f2d84b74db20cdb0f64a 605 SMART SM00388 379 450 1.5E-8 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS03995 5381adb38dc5ca4810e0c56a2f12c7d9 581 Pfam PF00999 Sodium/hydrogen exchanger family 14 387 1.8E-69 T 26-04-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4V04_RS03995 5381adb38dc5ca4810e0c56a2f12c7d9 581 Gene3D G3DSA:3.40.50.720 427 558 1.0E-24 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03995 5381adb38dc5ca4810e0c56a2f12c7d9 581 SUPERFAMILY SSF51735 427 562 2.1E-20 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03995 5381adb38dc5ca4810e0c56a2f12c7d9 581 Pfam PF02254 TrkA-N domain 432 530 2.1E-17 T 26-04-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4V04_RS12035 5b3903ba8d35e0660a0f345213e9fc78 453 SUPERFAMILY SSF63418 5 101 2.22E-23 T 26-04-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4V04_RS12035 5b3903ba8d35e0660a0f345213e9fc78 453 Pfam PF01225 Mur ligase family, catalytic domain 29 75 3.9E-8 T 26-04-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4V04_RS12035 5b3903ba8d35e0660a0f345213e9fc78 453 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 34 445 7.4E-116 T 26-04-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS12035 5b3903ba8d35e0660a0f345213e9fc78 453 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 6 447 28.874 T 26-04-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS12035 5b3903ba8d35e0660a0f345213e9fc78 453 Pfam PF08245 Mur ligase middle domain 109 292 7.6E-36 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS12035 5b3903ba8d35e0660a0f345213e9fc78 453 Gene3D G3DSA:3.90.190.20 312 449 2.0E-40 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS12035 5b3903ba8d35e0660a0f345213e9fc78 453 SUPERFAMILY SSF53244 313 445 2.52E-34 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS12035 5b3903ba8d35e0660a0f345213e9fc78 453 Pfam PF02875 Mur ligase family, glutamate ligase domain 313 392 3.2E-15 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS12035 5b3903ba8d35e0660a0f345213e9fc78 453 Gene3D G3DSA:3.40.1390.10 5 84 1.3E-23 T 26-04-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4V04_RS12035 5b3903ba8d35e0660a0f345213e9fc78 453 Gene3D G3DSA:3.40.1190.10 86 311 1.7E-59 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS12035 5b3903ba8d35e0660a0f345213e9fc78 453 SUPERFAMILY SSF53623 104 312 9.16E-48 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS02255 5750cabcdb3504fc8c7e31a0e3ddbf77 235 SUPERFAMILY SSF52266 99 190 1.03E-7 T 26-04-2017 IPR013830 SGNH hydrolase-type esterase domain A4V04_RS02255 5750cabcdb3504fc8c7e31a0e3ddbf77 235 Gene3D G3DSA:3.40.50.1110 101 190 6.3E-6 T 26-04-2017 IPR013830 SGNH hydrolase-type esterase domain A4V04_RS12400 f155d20649bb1990cba47d87586d06ef 237 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 15 194 2.3E-68 T 26-04-2017 IPR022301 Integral membrane protein YjbE A4V04_RS12400 f155d20649bb1990cba47d87586d06ef 237 Pfam PF03741 Integral membrane protein TerC family 18 193 5.0E-47 T 26-04-2017 IPR005496 Integral membrane protein TerC GO:0016021 A4V04_RS08325 17470c10b354fe2fd7f06ca030372403 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.4E-10 T 26-04-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4V04_RS08325 17470c10b354fe2fd7f06ca030372403 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.4E-10 T 26-04-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4V04_RS08325 17470c10b354fe2fd7f06ca030372403 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 1.4E-10 T 26-04-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4V04_RS08325 17470c10b354fe2fd7f06ca030372403 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 1.4E-10 T 26-04-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4V04_RS08325 17470c10b354fe2fd7f06ca030372403 166 Gene3D G3DSA:1.10.10.10 7 142 2.4E-33 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS08325 17470c10b354fe2fd7f06ca030372403 166 SUPERFAMILY SSF46785 9 148 1.29E-27 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS08325 17470c10b354fe2fd7f06ca030372403 166 SMART SM00347 26 128 2.4E-16 T 26-04-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4V04_RS08325 17470c10b354fe2fd7f06ca030372403 166 Pfam PF01047 MarR family 41 93 1.3E-8 T 26-04-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4V04_RS08040 2825e5f6ca333e5e9f30b10446646370 299 Pfam PF08543 Phosphomethylpyrimidine kinase 86 261 6.0E-12 T 26-04-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 A4V04_RS08040 2825e5f6ca333e5e9f30b10446646370 299 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 2 297 6.5E-79 T 26-04-2017 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4V04_RS08040 2825e5f6ca333e5e9f30b10446646370 299 SUPERFAMILY SSF53613 3 279 2.62E-55 T 26-04-2017 IPR029056 Ribokinase-like A4V04_RS08040 2825e5f6ca333e5e9f30b10446646370 299 Gene3D G3DSA:3.40.1190.20 4 296 1.3E-72 T 26-04-2017 IPR029056 Ribokinase-like A4V04_RS00165 306fb4eec18c9848a756bf9282e8c493 124 SMART SM00411 23 112 7.1E-34 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS00165 306fb4eec18c9848a756bf9282e8c493 124 Gene3D G3DSA:4.10.520.10 22 113 1.5E-30 T 26-04-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4V04_RS00165 306fb4eec18c9848a756bf9282e8c493 124 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 68 87 - T 26-04-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A4V04_RS00165 306fb4eec18c9848a756bf9282e8c493 124 PRINTS PR01727 Prokaryotic integration host factor signature 96 110 4.2E-13 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS00165 306fb4eec18c9848a756bf9282e8c493 124 PRINTS PR01727 Prokaryotic integration host factor signature 62 77 4.2E-13 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS00165 306fb4eec18c9848a756bf9282e8c493 124 PRINTS PR01727 Prokaryotic integration host factor signature 80 93 4.2E-13 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS00165 306fb4eec18c9848a756bf9282e8c493 124 SUPERFAMILY SSF47729 23 112 5.59E-28 T 26-04-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4V04_RS00165 306fb4eec18c9848a756bf9282e8c493 124 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 21 117 27.06 T 26-04-2017 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 A4V04_RS00165 306fb4eec18c9848a756bf9282e8c493 124 Pfam PF00216 Bacterial DNA-binding protein 23 111 3.2E-27 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 SMART SM00316 27 95 0.0063 T 26-04-2017 IPR022967 RNA-binding domain, S1 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 SMART SM00316 283 355 2.4E-25 T 26-04-2017 IPR022967 RNA-binding domain, S1 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 SMART SM00316 370 442 1.5E-22 T 26-04-2017 IPR022967 RNA-binding domain, S1 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 SMART SM00316 198 268 4.0E-29 T 26-04-2017 IPR022967 RNA-binding domain, S1 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 SMART SM00316 111 179 1.9E-10 T 26-04-2017 IPR022967 RNA-binding domain, S1 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 SMART SM00316 457 528 6.9E-22 T 26-04-2017 IPR022967 RNA-binding domain, S1 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 SUPERFAMILY SSF50249 198 284 5.29E-26 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 SUPERFAMILY SSF50249 111 192 2.26E-15 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 PRINTS PR00681 Ribosomal protein S1 signature 116 132 2.5E-81 T 26-04-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 PRINTS PR00681 Ribosomal protein S1 signature 134 151 2.5E-81 T 26-04-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 PRINTS PR00681 Ribosomal protein S1 signature 92 111 2.5E-81 T 26-04-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 PRINTS PR00681 Ribosomal protein S1 signature 47 61 2.5E-81 T 26-04-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 PRINTS PR00681 Ribosomal protein S1 signature 220 241 2.5E-81 T 26-04-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 PRINTS PR00681 Ribosomal protein S1 signature 29 47 2.5E-81 T 26-04-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 PRINTS PR00681 Ribosomal protein S1 signature 338 356 2.5E-81 T 26-04-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 PRINTS PR00681 Ribosomal protein S1 signature 163 183 2.5E-81 T 26-04-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 PRINTS PR00681 Ribosomal protein S1 signature 298 317 2.5E-81 T 26-04-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 Gene3D G3DSA:2.40.50.140 29 108 4.9E-9 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 Gene3D G3DSA:2.40.50.140 290 369 7.6E-31 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 SUPERFAMILY SSF50249 437 542 1.19E-23 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 Gene3D G3DSA:2.40.50.140 192 270 5.1E-30 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 Gene3D G3DSA:2.40.50.140 109 180 8.3E-18 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 Gene3D G3DSA:2.40.50.140 451 529 6.0E-22 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 Gene3D G3DSA:2.40.50.140 370 450 6.7E-26 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 SUPERFAMILY SSF50249 263 365 3.65E-27 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 11 528 3.8E-206 T 26-04-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 SUPERFAMILY SSF50249 11 121 2.96E-18 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 SUPERFAMILY SSF50249 355 445 1.86E-21 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 PIRSF PIRSF002111 1 542 1.7E-215 T 26-04-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 Pfam PF00575 S1 RNA binding domain 456 528 3.1E-18 T 26-04-2017 IPR003029 S1 domain GO:0003676 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 Pfam PF00575 S1 RNA binding domain 369 442 2.3E-18 T 26-04-2017 IPR003029 S1 domain GO:0003676 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 Pfam PF00575 S1 RNA binding domain 27 93 2.3E-6 T 26-04-2017 IPR003029 S1 domain GO:0003676 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 Pfam PF00575 S1 RNA binding domain 285 355 1.1E-21 T 26-04-2017 IPR003029 S1 domain GO:0003676 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 Pfam PF00575 S1 RNA binding domain 198 268 4.5E-23 T 26-04-2017 IPR003029 S1 domain GO:0003676 A4V04_RS01510 eb2dff1cf678f79f2159aca77adb2c26 565 Pfam PF00575 S1 RNA binding domain 111 179 7.2E-13 T 26-04-2017 IPR003029 S1 domain GO:0003676 A4V04_RS13020 1ded8c75858817c462f8172133caf968 1019 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 121 736 2.3E-94 T 26-04-2017 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 A4V04_RS13020 1ded8c75858817c462f8172133caf968 1019 SMART SM00487 253 462 3.4E-13 T 26-04-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4V04_RS13020 1ded8c75858817c462f8172133caf968 1019 SUPERFAMILY SSF52540 252 444 1.0E-25 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13020 1ded8c75858817c462f8172133caf968 1019 Pfam PF04851 Type III restriction enzyme, res subunit 257 432 1.4E-28 T 26-04-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4V04_RS13020 1ded8c75858817c462f8172133caf968 1019 SUPERFAMILY SSF52540 637 706 6.13E-8 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13020 1ded8c75858817c462f8172133caf968 1019 SUPERFAMILY SSF52540 394 463 6.13E-8 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13020 1ded8c75858817c462f8172133caf968 1019 SUPERFAMILY SSF52540 550 574 6.13E-8 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13020 1ded8c75858817c462f8172133caf968 1019 Gene3D G3DSA:3.40.50.300 637 705 6.3E-5 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13020 1ded8c75858817c462f8172133caf968 1019 Gene3D G3DSA:3.40.50.300 553 579 6.3E-5 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13020 1ded8c75858817c462f8172133caf968 1019 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 5 203 7.0E-25 T 26-04-2017 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 A4V04_RS13020 1ded8c75858817c462f8172133caf968 1019 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 746 1007 5.5E-30 T 26-04-2017 IPR022625 Type-1 restriction enzyme R protein, C-terminal A4V04_RS13020 1ded8c75858817c462f8172133caf968 1019 Gene3D G3DSA:3.40.50.300 252 437 5.0E-23 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01785 28a914732a280382ab1fcf3162bea161 338 Pfam PF06834 TraU protein 25 331 2.4E-104 T 26-04-2017 IPR009649 TraU A4V04_RS12245 cb1ef5990f5fece7c6d3ef9e86c753b3 322 Pfam PF03547 Membrane transport protein 10 153 6.7E-11 T 26-04-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A4V04_RS12245 cb1ef5990f5fece7c6d3ef9e86c753b3 322 Pfam PF03547 Membrane transport protein 171 316 1.0E-11 T 26-04-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A4V04_RS11360 328acdfd337189892c3ea2384a41adf1 140 PIRSF PIRSF016821 9 135 2.8E-39 T 26-04-2017 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 A4V04_RS11360 328acdfd337189892c3ea2384a41adf1 140 SMART SM00363 12 74 6.8E-5 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS11360 328acdfd337189892c3ea2384a41adf1 140 Gene3D G3DSA:3.10.290.10 8 106 3.1E-33 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS11360 328acdfd337189892c3ea2384a41adf1 140 SUPERFAMILY SSF55174 9 102 2.62E-26 T 26-04-2017 A4V04_RS11360 328acdfd337189892c3ea2384a41adf1 140 Pfam PF01479 S4 domain 13 58 2.8E-11 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 SUPERFAMILY SSF88659 201 300 1.57E-17 T 26-04-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 268 294 - T 26-04-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 92 105 - T 26-04-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 PRINTS PR00046 Major sigma-70 factor signature 92 105 2.2E-17 T 26-04-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 PRINTS PR00046 Major sigma-70 factor signature 283 294 2.2E-17 T 26-04-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 PRINTS PR00046 Major sigma-70 factor signature 116 124 2.2E-17 T 26-04-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 PRINTS PR00046 Major sigma-70 factor signature 268 283 2.2E-17 T 26-04-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 Pfam PF04542 Sigma-70 region 2 68 136 9.4E-20 T 26-04-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 PIRSF PIRSF000770 28 304 1.1E-34 T 26-04-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 29 299 2.5E-108 T 26-04-2017 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 63 298 3.9E-36 T 26-04-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 SUPERFAMILY SSF88946 27 137 1.96E-39 T 26-04-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 Gene3D G3DSA:1.10.10.10 237 302 1.5E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 Pfam PF04545 Sigma-70, region 4 241 296 2.7E-15 T 26-04-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09540 e3ad43575725b498d6d1606ff39866a1 305 Gene3D G3DSA:1.10.601.10 30 135 8.1E-38 T 26-04-2017 A4V04_RS00690 bed6f4b1e533adbcbaa9eb514c2bbd72 214 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 18 209 2.7E-62 T 26-04-2017 IPR015796 Impact family, bacterial/archaeal A4V04_RS00690 bed6f4b1e533adbcbaa9eb514c2bbd72 214 SUPERFAMILY SSF54980 144 210 4.73E-9 T 26-04-2017 IPR009022 Elongation factor G, III-V domain A4V04_RS00690 bed6f4b1e533adbcbaa9eb514c2bbd72 214 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 86 115 - T 26-04-2017 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site A4V04_RS00690 bed6f4b1e533adbcbaa9eb514c2bbd72 214 Pfam PF09186 Domain of unknown function (DUF1949) 147 201 1.5E-8 T 26-04-2017 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal A4V04_RS00690 bed6f4b1e533adbcbaa9eb514c2bbd72 214 Gene3D G3DSA:3.30.70.240 144 210 5.8E-11 T 26-04-2017 IPR000640 Translation elongation factor EFG, V domain A4V04_RS00690 bed6f4b1e533adbcbaa9eb514c2bbd72 214 Gene3D G3DSA:3.30.230.30 16 138 1.0E-42 T 26-04-2017 IPR001498 Impact, N-terminal A4V04_RS00690 bed6f4b1e533adbcbaa9eb514c2bbd72 214 Pfam PF01205 Uncharacterized protein family UPF0029 24 131 3.1E-29 T 26-04-2017 IPR001498 Impact, N-terminal A4V04_RS00690 bed6f4b1e533adbcbaa9eb514c2bbd72 214 SUPERFAMILY SSF54211 12 139 7.97E-42 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS09405 3b27b8e27a08693728def805ff8c3e58 205 Gene3D G3DSA:1.10.357.10 11 179 4.7E-28 T 26-04-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4V04_RS09405 3b27b8e27a08693728def805ff8c3e58 205 SUPERFAMILY SSF46689 9 83 1.61E-10 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS09405 3b27b8e27a08693728def805ff8c3e58 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 68 5.6E-7 T 26-04-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4V04_RS12775 c105b3b05de904bb6563c12c3492fd25 203 Pfam PF01966 HD domain 68 161 8.2E-12 T 26-04-2017 IPR006674 HD domain A4V04_RS12775 c105b3b05de904bb6563c12c3492fd25 203 SUPERFAMILY SSF109604 8 164 1.85E-61 T 26-04-2017 A4V04_RS12775 c105b3b05de904bb6563c12c3492fd25 203 SMART SM00471 64 177 8.3E-8 T 26-04-2017 IPR003607 HD/PDEase domain A4V04_RS12775 c105b3b05de904bb6563c12c3492fd25 203 Gene3D G3DSA:1.10.3210.10 25 164 2.0E-54 T 26-04-2017 IPR006674 HD domain A4V04_RS12775 c105b3b05de904bb6563c12c3492fd25 203 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 30 165 2.4E-57 T 26-04-2017 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 A4V04_RS08820 457bb70293539bed316211f9ca73890e 472 SUPERFAMILY SSF51556 59 236 2.27E-16 T 26-04-2017 IPR032466 Metal-dependent hydrolase A4V04_RS08820 457bb70293539bed316211f9ca73890e 472 SUPERFAMILY SSF51338 396 430 3.82E-13 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS08820 457bb70293539bed316211f9ca73890e 472 SUPERFAMILY SSF51338 2 60 3.82E-13 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS08820 457bb70293539bed316211f9ca73890e 472 Gene3D G3DSA:3.20.20.140 346 426 3.9E-18 T 26-04-2017 A4V04_RS08820 457bb70293539bed316211f9ca73890e 472 Gene3D G3DSA:3.20.20.140 69 287 3.9E-18 T 26-04-2017 A4V04_RS08820 457bb70293539bed316211f9ca73890e 472 Pfam PF01979 Amidohydrolase family 57 420 2.7E-13 T 26-04-2017 IPR006680 Amidohydrolase-related GO:0016787 A4V04_RS08820 457bb70293539bed316211f9ca73890e 472 Gene3D G3DSA:2.30.40.10 5 68 6.2E-13 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS12105 24bbc5d6e0250eae73df270acc4369c7 404 PRINTS PR01035 Tetracycline resistance protein signature 250 269 1.4E-5 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS12105 24bbc5d6e0250eae73df270acc4369c7 404 PRINTS PR01035 Tetracycline resistance protein signature 220 236 1.4E-5 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS12105 24bbc5d6e0250eae73df270acc4369c7 404 PRINTS PR01035 Tetracycline resistance protein signature 339 361 1.4E-5 T 26-04-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4V04_RS12105 24bbc5d6e0250eae73df270acc4369c7 404 Pfam PF07690 Major Facilitator Superfamily 11 241 1.6E-34 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS12105 24bbc5d6e0250eae73df270acc4369c7 404 Gene3D G3DSA:1.20.1250.20 7 192 6.4E-36 T 26-04-2017 A4V04_RS12105 24bbc5d6e0250eae73df270acc4369c7 404 Gene3D G3DSA:1.20.1250.20 209 391 3.3E-28 T 26-04-2017 A4V04_RS12105 24bbc5d6e0250eae73df270acc4369c7 404 SUPERFAMILY SSF103473 6 392 5.89E-64 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS06465 ea84311581bf954f4c4e72bd6484b54d 90 Pfam PF15943 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 17 67 1.0E-13 T 26-04-2017 IPR031856 Putative bacterial antitoxin YdaS A4V04_RS06465 ea84311581bf954f4c4e72bd6484b54d 90 SUPERFAMILY SSF47413 16 65 1.38E-6 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS06465 ea84311581bf954f4c4e72bd6484b54d 90 Gene3D G3DSA:1.10.260.40 17 71 9.4E-15 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS10345 9ce8152b2ba562a25f416923c1218ba4 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 200 1.1E-15 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10345 9ce8152b2ba562a25f416923c1218ba4 210 Gene3D G3DSA:3.40.50.2300 14 135 3.9E-31 T 26-04-2017 A4V04_RS10345 9ce8152b2ba562a25f416923c1218ba4 210 SMART SM00421 146 203 1.8E-12 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10345 9ce8152b2ba562a25f416923c1218ba4 210 SUPERFAMILY SSF46894 142 202 9.18E-15 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS10345 9ce8152b2ba562a25f416923c1218ba4 210 Pfam PF00072 Response regulator receiver domain 15 123 4.0E-25 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS10345 9ce8152b2ba562a25f416923c1218ba4 210 Gene3D G3DSA:1.10.10.10 146 201 1.0E-16 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10345 9ce8152b2ba562a25f416923c1218ba4 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 9.8E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10345 9ce8152b2ba562a25f416923c1218ba4 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 9.8E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10345 9ce8152b2ba562a25f416923c1218ba4 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 9.8E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10345 9ce8152b2ba562a25f416923c1218ba4 210 SMART SM00448 12 123 2.7E-22 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS10345 9ce8152b2ba562a25f416923c1218ba4 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10345 9ce8152b2ba562a25f416923c1218ba4 210 SUPERFAMILY SSF52172 15 142 2.99E-32 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS10655 5a0133274539f37d0fc796e77fc582d3 80 Hamap MF_01396 ATP synthase subunit c [atpH]. 7 75 13.312 T 26-04-2017 A4V04_RS10655 5a0133274539f37d0fc796e77fc582d3 80 SUPERFAMILY SSF81333 4 77 1.57E-18 T 26-04-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A4V04_RS10655 5a0133274539f37d0fc796e77fc582d3 80 ProSitePatterns PS00605 ATP synthase c subunit signature. 38 59 - T 26-04-2017 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 A4V04_RS10655 5a0133274539f37d0fc796e77fc582d3 80 Pfam PF00137 ATP synthase subunit C 9 71 4.3E-11 T 26-04-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A4V04_RS10655 5a0133274539f37d0fc796e77fc582d3 80 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 19 75 1.4E-21 T 26-04-2017 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A4V04_RS10655 5a0133274539f37d0fc796e77fc582d3 80 Gene3D G3DSA:1.20.20.10 3 77 2.5E-33 T 26-04-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 A4V04_RS08140 9695c5197ca6f95255f4df9bc5ee1fbd 230 Pfam PF00072 Response regulator receiver domain 4 113 6.6E-29 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS08140 9695c5197ca6f95255f4df9bc5ee1fbd 230 SMART SM00448 2 113 1.9E-39 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS08140 9695c5197ca6f95255f4df9bc5ee1fbd 230 SUPERFAMILY SSF52172 1 180 5.83E-39 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS08140 9695c5197ca6f95255f4df9bc5ee1fbd 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 218 2.5E-14 T 26-04-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4V04_RS08140 9695c5197ca6f95255f4df9bc5ee1fbd 230 SMART SM00862 146 220 2.7E-12 T 26-04-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4V04_RS08140 9695c5197ca6f95255f4df9bc5ee1fbd 230 Gene3D G3DSA:1.10.10.10 126 221 6.0E-20 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS08140 9695c5197ca6f95255f4df9bc5ee1fbd 230 Gene3D G3DSA:3.40.50.2300 1 123 1.6E-37 T 26-04-2017 A4V04_RS11460 487144ea9e6f69c8de16b124f8bde66d 527 Gene3D G3DSA:3.40.50.300 192 355 1.6E-40 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11460 487144ea9e6f69c8de16b124f8bde66d 527 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 206 219 - T 26-04-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A4V04_RS11460 487144ea9e6f69c8de16b124f8bde66d 527 PIRSF PIRSF037354 1 527 1.3E-234 T 26-04-2017 IPR017183 Sigma54-dependent transcriptional activator, RtcR GO:0003700|GO:0006355 A4V04_RS11460 487144ea9e6f69c8de16b124f8bde66d 527 SMART SM00382 202 348 7.3E-6 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS11460 487144ea9e6f69c8de16b124f8bde66d 527 Pfam PF00158 Sigma-54 interaction domain 184 349 7.3E-50 T 26-04-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A4V04_RS11460 487144ea9e6f69c8de16b124f8bde66d 527 SUPERFAMILY SSF52540 192 431 1.06E-48 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11460 487144ea9e6f69c8de16b124f8bde66d 527 Gene3D G3DSA:1.10.8.60 358 434 8.8E-11 T 26-04-2017 A4V04_RS11460 487144ea9e6f69c8de16b124f8bde66d 527 Pfam PF06956 Regulator of RNA terminal phosphate cyclase 2 180 7.1E-77 T 26-04-2017 IPR009715 Regulator of RNA terminal phosphate cyclase A4V04_RS07655 d7348a31b864dc2993bba1b17e6fe659 236 Pfam PF00072 Response regulator receiver domain 8 119 6.3E-30 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS07655 d7348a31b864dc2993bba1b17e6fe659 236 SMART SM00862 157 233 1.5E-14 T 26-04-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4V04_RS07655 d7348a31b864dc2993bba1b17e6fe659 236 SMART SM00448 6 118 3.6E-40 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS07655 d7348a31b864dc2993bba1b17e6fe659 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 233 3.1E-17 T 26-04-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4V04_RS07655 d7348a31b864dc2993bba1b17e6fe659 236 Gene3D G3DSA:1.10.10.10 134 234 1.5E-24 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07655 d7348a31b864dc2993bba1b17e6fe659 236 SUPERFAMILY SSF52172 6 174 4.7E-40 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS07655 d7348a31b864dc2993bba1b17e6fe659 236 Gene3D G3DSA:3.40.50.2300 4 130 1.1E-41 T 26-04-2017 A4V04_RS10265 2531bf46cdec54972fd666fd85420626 128 Gene3D G3DSA:1.10.260.40 5 61 1.6E-8 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS10265 2531bf46cdec54972fd666fd85420626 128 SUPERFAMILY SSF47413 9 60 5.36E-9 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS10265 2531bf46cdec54972fd666fd85420626 128 SMART SM00530 15 69 0.0017 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS10265 2531bf46cdec54972fd666fd85420626 128 Pfam PF01381 Helix-turn-helix 17 56 5.0E-6 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS01290 2ab7e3c9afe3c67b2b48bc249b745d6c 314 SUPERFAMILY SSF53756 3 311 7.85E-40 T 26-04-2017 A4V04_RS01290 2ab7e3c9afe3c67b2b48bc249b745d6c 314 Gene3D G3DSA:3.40.50.2000 163 311 3.4E-22 T 26-04-2017 A4V04_RS01290 2ab7e3c9afe3c67b2b48bc249b745d6c 314 Gene3D G3DSA:3.40.50.2000 3 131 7.5E-14 T 26-04-2017 A4V04_RS01290 2ab7e3c9afe3c67b2b48bc249b745d6c 314 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 78 296 4.5E-32 T 26-04-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 A4V04_RS08420 ed59fc8845dd7b8299911e1324ee5320 236 SUPERFAMILY SSF56784 7 230 2.72E-51 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS08420 ed59fc8845dd7b8299911e1324ee5320 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 198 6.3E-38 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS08420 ed59fc8845dd7b8299911e1324ee5320 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 111 124 1.5E-10 T 26-04-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4V04_RS08420 ed59fc8845dd7b8299911e1324ee5320 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 1.5E-10 T 26-04-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4V04_RS08420 ed59fc8845dd7b8299911e1324ee5320 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 160 180 1.5E-10 T 26-04-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4V04_RS08420 ed59fc8845dd7b8299911e1324ee5320 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 11 22 1.5E-10 T 26-04-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4V04_RS08420 ed59fc8845dd7b8299911e1324ee5320 236 Gene3D G3DSA:1.10.150.240 28 88 1.8E-8 T 26-04-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 A4V04_RS08420 ed59fc8845dd7b8299911e1324ee5320 236 Gene3D G3DSA:3.40.50.1000 93 228 5.2E-39 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS08420 ed59fc8845dd7b8299911e1324ee5320 236 Gene3D G3DSA:3.40.50.1000 3 27 5.2E-39 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS08420 ed59fc8845dd7b8299911e1324ee5320 236 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 107 191 7.5E-6 T 26-04-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4V04_RS08680 c3be5e0cde9ee5c7d9c36e9fec388bc0 297 Pfam PF03471 Transporter associated domain 201 277 9.2E-21 T 26-04-2017 IPR005170 Transporter-associated domain A4V04_RS08680 c3be5e0cde9ee5c7d9c36e9fec388bc0 297 SUPERFAMILY SSF54631 54 191 7.2E-31 T 26-04-2017 A4V04_RS08680 c3be5e0cde9ee5c7d9c36e9fec388bc0 297 SMART SM01091 200 278 5.3E-28 T 26-04-2017 IPR005170 Transporter-associated domain A4V04_RS08680 c3be5e0cde9ee5c7d9c36e9fec388bc0 297 Pfam PF00571 CBS domain 136 183 2.8E-5 T 26-04-2017 IPR000644 CBS domain A4V04_RS08680 c3be5e0cde9ee5c7d9c36e9fec388bc0 297 Pfam PF00571 CBS domain 71 122 1.6E-5 T 26-04-2017 IPR000644 CBS domain A4V04_RS08680 c3be5e0cde9ee5c7d9c36e9fec388bc0 297 SUPERFAMILY SSF56176 198 284 1.06E-22 T 26-04-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4V04_RS08680 c3be5e0cde9ee5c7d9c36e9fec388bc0 297 SMART SM00116 74 123 0.02 T 26-04-2017 IPR000644 CBS domain A4V04_RS08680 c3be5e0cde9ee5c7d9c36e9fec388bc0 297 SMART SM00116 135 183 9.0 T 26-04-2017 IPR000644 CBS domain A4V04_RS08680 c3be5e0cde9ee5c7d9c36e9fec388bc0 297 Gene3D G3DSA:3.30.465.10 191 277 6.9E-26 T 26-04-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4V04_RS08680 c3be5e0cde9ee5c7d9c36e9fec388bc0 297 Gene3D G3DSA:3.10.580.10 53 190 4.6E-19 T 26-04-2017 A4V04_RS04955 fa932af401f05439c895d488e0e1d7e7 479 SUPERFAMILY SSF56425 260 405 3.44E-45 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04955 fa932af401f05439c895d488e0e1d7e7 479 SUPERFAMILY SSF51905 20 277 2.06E-65 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04955 fa932af401f05439c895d488e0e1d7e7 479 SUPERFAMILY SSF51905 404 461 2.06E-65 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04955 fa932af401f05439c895d488e0e1d7e7 479 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 25 456 1.1E-150 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS04955 fa932af401f05439c895d488e0e1d7e7 479 Pfam PF00890 FAD binding domain 25 444 7.3E-98 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04955 fa932af401f05439c895d488e0e1d7e7 479 Gene3D G3DSA:3.50.50.60 22 254 1.0E-103 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04955 fa932af401f05439c895d488e0e1d7e7 479 Gene3D G3DSA:3.50.50.60 401 461 1.0E-103 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04955 fa932af401f05439c895d488e0e1d7e7 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 409 431 9.4E-6 T 26-04-2017 A4V04_RS04955 fa932af401f05439c895d488e0e1d7e7 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 26 45 9.4E-6 T 26-04-2017 A4V04_RS04955 fa932af401f05439c895d488e0e1d7e7 479 Gene3D G3DSA:3.90.700.10 260 397 8.6E-43 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10315 5d9533629d91df1f5d968ac4e7d31f66 255 Pfam PF03167 Uracil DNA glycosylase superfamily 40 225 7.5E-5 T 26-04-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4V04_RS10315 5d9533629d91df1f5d968ac4e7d31f66 255 ProDom PD315856 ORF119 CPE0798 YOXB 36 221 3.0E-32 T 26-04-2017 IPR020530 Uncharacterised protein family, YoxB A4V04_RS01700 d574fd2bb944fef3b6b80a94d64a13aa 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 2.8E-8 T 26-04-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4V04_RS01700 d574fd2bb944fef3b6b80a94d64a13aa 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 2.8E-8 T 26-04-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4V04_RS01700 d574fd2bb944fef3b6b80a94d64a13aa 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 2.8E-8 T 26-04-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4V04_RS01700 d574fd2bb944fef3b6b80a94d64a13aa 102 Gene3D G3DSA:1.10.10.10 7 89 2.6E-23 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01700 d574fd2bb944fef3b6b80a94d64a13aa 102 SMART SM00418 13 87 8.1E-17 T 26-04-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4V04_RS01700 d574fd2bb944fef3b6b80a94d64a13aa 102 Pfam PF01022 Bacterial regulatory protein, arsR family 20 65 9.8E-12 T 26-04-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4V04_RS01700 d574fd2bb944fef3b6b80a94d64a13aa 102 SUPERFAMILY SSF46785 7 88 2.42E-20 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS00950 364aafe29518227e419e5b6b30cd5543 162 SUPERFAMILY SSF55729 1 156 1.89E-23 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS00950 364aafe29518227e419e5b6b30cd5543 162 Gene3D G3DSA:3.40.630.30 2 158 1.8E-37 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS00950 364aafe29518227e419e5b6b30cd5543 162 Pfam PF00583 Acetyltransferase (GNAT) family 62 138 6.8E-9 T 26-04-2017 IPR000182 GNAT domain GO:0008080 A4V04_RS08840 820446b982efc0f58245264dbc75a169 207 Pfam PF01810 LysE type translocator 15 205 6.3E-40 T 26-04-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 A4V04_RS08840 820446b982efc0f58245264dbc75a169 207 PIRSF PIRSF006324 1 207 4.6E-54 T 26-04-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 A4V04_RS12120 3d9d7715cb3a50c9ac1a4c57fdff8b2a 476 PRINTS PR00145 Argininosuccinate lyase family signature 252 268 1.1E-12 T 26-04-2017 A4V04_RS12120 3d9d7715cb3a50c9ac1a4c57fdff8b2a 476 PRINTS PR00145 Argininosuccinate lyase family signature 166 182 1.1E-12 T 26-04-2017 A4V04_RS12120 3d9d7715cb3a50c9ac1a4c57fdff8b2a 476 PRINTS PR00145 Argininosuccinate lyase family signature 115 135 1.1E-12 T 26-04-2017 A4V04_RS12120 3d9d7715cb3a50c9ac1a4c57fdff8b2a 476 PRINTS PR00145 Argininosuccinate lyase family signature 74 96 1.1E-12 T 26-04-2017 A4V04_RS12120 3d9d7715cb3a50c9ac1a4c57fdff8b2a 476 Gene3D G3DSA:1.20.200.10 80 349 1.3E-50 T 26-04-2017 A4V04_RS12120 3d9d7715cb3a50c9ac1a4c57fdff8b2a 476 SUPERFAMILY SSF48557 8 444 9.27E-72 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS12120 3d9d7715cb3a50c9ac1a4c57fdff8b2a 476 Pfam PF14698 Argininosuccinate lyase C-terminal 343 421 2.4E-11 T 26-04-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS12120 3d9d7715cb3a50c9ac1a4c57fdff8b2a 476 Gene3D G3DSA:1.10.40.30 350 422 1.8E-12 T 26-04-2017 A4V04_RS12120 3d9d7715cb3a50c9ac1a4c57fdff8b2a 476 Pfam PF00206 Lyase 73 277 8.5E-27 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS12120 3d9d7715cb3a50c9ac1a4c57fdff8b2a 476 PRINTS PR00149 Fumarate lyase superfamily signature 206 233 1.7E-8 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS12120 3d9d7715cb3a50c9ac1a4c57fdff8b2a 476 PRINTS PR00149 Fumarate lyase superfamily signature 120 138 1.7E-8 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS12120 3d9d7715cb3a50c9ac1a4c57fdff8b2a 476 PRINTS PR00149 Fumarate lyase superfamily signature 252 268 1.7E-8 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS12120 3d9d7715cb3a50c9ac1a4c57fdff8b2a 476 PRINTS PR00149 Fumarate lyase superfamily signature 75 93 1.7E-8 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS12585 4101a2a392787807d65acd3f2258726c 128 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 2 106 31.26 T 26-04-2017 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A4V04_RS12585 4101a2a392787807d65acd3f2258726c 128 SUPERFAMILY SSF141734 2 112 7.59E-47 T 26-04-2017 A4V04_RS12585 4101a2a392787807d65acd3f2258726c 128 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 51 105 4.0E-18 T 26-04-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A4V04_RS12585 4101a2a392787807d65acd3f2258726c 128 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 28 102 2.3E-34 T 26-04-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A4V04_RS12010 07b7ae6ca8fe7087acd1ec01a6a83b04 467 Pfam PF02875 Mur ligase family, glutamate ligase domain 313 401 8.6E-19 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS12010 07b7ae6ca8fe7087acd1ec01a6a83b04 467 SUPERFAMILY SSF53244 310 459 5.8E-43 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS12010 07b7ae6ca8fe7087acd1ec01a6a83b04 467 Pfam PF01225 Mur ligase family, catalytic domain 7 103 1.1E-25 T 26-04-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4V04_RS12010 07b7ae6ca8fe7087acd1ec01a6a83b04 467 Pfam PF08245 Mur ligase middle domain 109 290 2.1E-30 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS12010 07b7ae6ca8fe7087acd1ec01a6a83b04 467 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 4 464 42.284 T 26-04-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS12010 07b7ae6ca8fe7087acd1ec01a6a83b04 467 SUPERFAMILY SSF51984 5 91 3.4E-30 T 26-04-2017 A4V04_RS12010 07b7ae6ca8fe7087acd1ec01a6a83b04 467 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 7 457 2.7E-164 T 26-04-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS12010 07b7ae6ca8fe7087acd1ec01a6a83b04 467 SUPERFAMILY SSF53623 90 308 2.29E-68 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS12010 07b7ae6ca8fe7087acd1ec01a6a83b04 467 Gene3D G3DSA:3.40.1190.10 93 312 3.5E-80 T 26-04-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4V04_RS12010 07b7ae6ca8fe7087acd1ec01a6a83b04 467 Gene3D G3DSA:3.90.190.20 313 461 2.9E-51 T 26-04-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4V04_RS12010 07b7ae6ca8fe7087acd1ec01a6a83b04 467 Gene3D G3DSA:3.40.50.720 5 91 1.0E-34 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS07595 abcbffaa021b2327354974e84ceb556a 634 Pfam PF08676 MutL C terminal dimerisation domain 440 589 4.0E-45 T 26-04-2017 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 A4V04_RS07595 abcbffaa021b2327354974e84ceb556a 634 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 103 109 - T 26-04-2017 IPR014762 DNA mismatch repair, conserved site A4V04_RS07595 abcbffaa021b2327354974e84ceb556a 634 SUPERFAMILY SSF118116 439 632 1.7E-51 T 26-04-2017 A4V04_RS07595 abcbffaa021b2327354974e84ceb556a 634 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 214 328 3.0E-34 T 26-04-2017 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 A4V04_RS07595 abcbffaa021b2327354974e84ceb556a 634 Gene3D G3DSA:3.30.230.10 218 327 2.4E-35 T 26-04-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4V04_RS07595 abcbffaa021b2327354974e84ceb556a 634 SMART SM01340 211 329 4.8E-48 T 26-04-2017 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 A4V04_RS07595 abcbffaa021b2327354974e84ceb556a 634 SUPERFAMILY SSF55874 12 204 1.96E-47 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07595 abcbffaa021b2327354974e84ceb556a 634 SMART SM00853 444 590 3.9E-47 T 26-04-2017 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 A4V04_RS07595 abcbffaa021b2327354974e84ceb556a 634 Gene3D G3DSA:3.30.565.10 12 211 6.8E-65 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS07595 abcbffaa021b2327354974e84ceb556a 634 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 11 630 26.103 T 26-04-2017 IPR020667 DNA mismatch repair protein, MutL GO:0006298 A4V04_RS07595 abcbffaa021b2327354974e84ceb556a 634 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 12 309 4.3E-87 T 26-04-2017 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 A4V04_RS07595 abcbffaa021b2327354974e84ceb556a 634 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 129 5.1E-11 T 26-04-2017 A4V04_RS07595 abcbffaa021b2327354974e84ceb556a 634 SUPERFAMILY SSF54211 195 329 1.86E-33 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS09425 fbe4d50c0d868a1ea4b08aa83187f1c7 489 SUPERFAMILY SSF102114 71 446 2.22E-71 T 26-04-2017 A4V04_RS09425 fbe4d50c0d868a1ea4b08aa83187f1c7 489 Pfam PF04055 Radical SAM superfamily 76 237 2.1E-16 T 26-04-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 A4V04_RS09425 fbe4d50c0d868a1ea4b08aa83187f1c7 489 TIGRFAM TIGR04107 rSAM_HutW: putative heme utilization radical SAM enzyme HutW 34 452 5.8E-141 T 26-04-2017 IPR026332 Putative heme utilization radical SAM enzyme HutW A4V04_RS09425 fbe4d50c0d868a1ea4b08aa83187f1c7 489 Gene3D G3DSA:3.80.30.20 73 274 5.7E-28 T 26-04-2017 IPR023404 Radical SAM, alpha/beta horseshoe A4V04_RS09425 fbe4d50c0d868a1ea4b08aa83187f1c7 489 SMART SM00729 71 294 3.0E-37 T 26-04-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4V04_RS01130 9b676952fe93169b11bfb2d60cbe5a79 489 SMART SM00479 11 204 0.0017 T 26-04-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III A4V04_RS01130 9b676952fe93169b11bfb2d60cbe5a79 489 Pfam PF08411 Exonuclease C-terminal 214 482 1.6E-37 T 26-04-2017 IPR013620 Exonuclease C-terminal GO:0006281|GO:0008852 A4V04_RS01130 9b676952fe93169b11bfb2d60cbe5a79 489 Pfam PF00929 Exonuclease 14 193 3.2E-22 T 26-04-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III A4V04_RS01130 9b676952fe93169b11bfb2d60cbe5a79 489 SUPERFAMILY SSF53098 11 483 7.59E-79 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS01130 9b676952fe93169b11bfb2d60cbe5a79 489 PIRSF PIRSF000977 4 488 2.0E-128 T 26-04-2017 IPR023607 Exodeoxyribonuclease I GO:0004529 A4V04_RS01130 9b676952fe93169b11bfb2d60cbe5a79 489 Gene3D G3DSA:3.30.420.10 8 200 6.8E-63 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS10980 ea625563bcc90211c03f2e1fd1c1a46c 239 SMART SM00866 94 236 8.7E-11 T 26-04-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4V04_RS10980 ea625563bcc90211c03f2e1fd1c1a46c 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.9E-15 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS10980 ea625563bcc90211c03f2e1fd1c1a46c 239 SMART SM00345 15 74 6.8E-14 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS10980 ea625563bcc90211c03f2e1fd1c1a46c 239 Gene3D G3DSA:1.10.10.10 8 69 1.7E-21 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10980 ea625563bcc90211c03f2e1fd1c1a46c 239 SUPERFAMILY SSF64288 62 230 9.26E-25 T 26-04-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4V04_RS10980 ea625563bcc90211c03f2e1fd1c1a46c 239 Pfam PF07702 UTRA domain 100 231 1.6E-17 T 26-04-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4V04_RS10980 ea625563bcc90211c03f2e1fd1c1a46c 239 SUPERFAMILY SSF46785 8 78 2.85E-18 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10980 ea625563bcc90211c03f2e1fd1c1a46c 239 Gene3D G3DSA:3.40.1410.10 70 235 2.6E-29 T 26-04-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4V04_RS12435 b3302b4a00c5979fdb546543ec383584 580 Pfam PF01609 Transposase DDE domain 232 491 9.4E-7 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS12435 b3302b4a00c5979fdb546543ec383584 580 SUPERFAMILY SSF53098 384 509 3.26E-6 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS12435 b3302b4a00c5979fdb546543ec383584 580 SUPERFAMILY SSF53098 132 340 3.26E-6 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 TIGRFAM TIGR00038 efp: translation elongation factor P 3 184 4.0E-62 T 26-04-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 SMART SM00841 128 183 2.9E-30 T 26-04-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 Gene3D G3DSA:2.40.50.140 65 126 4.0E-18 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 1.4E-13 T 26-04-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 SUPERFAMILY SSF50104 1 62 1.2E-15 T 26-04-2017 IPR008991 Translation protein SH3-like domain A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 SUPERFAMILY SSF50249 65 126 1.41E-13 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 Pfam PF09285 Elongation factor P, C-terminal 129 183 1.9E-25 T 26-04-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 ProSitePatterns PS01275 Elongation factor P signature. 149 168 - T 26-04-2017 IPR013852 Translation elongation factor P/YeiP, conserved site A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 5.3E-19 T 26-04-2017 IPR013185 Translation elongation factor, KOW-like A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 Gene3D G3DSA:2.40.50.140 128 184 1.6E-27 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 PIRSF PIRSF005901 1 185 3.7E-58 T 26-04-2017 IPR020599 Translation elongation factor P/YeiP A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 SMART SM01185 67 120 5.4E-14 T 26-04-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 Gene3D G3DSA:2.30.30.30 1 62 4.1E-19 T 26-04-2017 IPR014722 Ribosomal protein L2 domain 2 A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 SUPERFAMILY SSF50249 128 184 4.11E-18 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS03345 a8d3cf4106f46ee3df2d77cc287185fa 185 Hamap MF_00141 Elongation factor P [efp]. 1 184 45.505 T 26-04-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A4V04_RS06965 cba2dae122399f5b54ebf2b4679002b8 210 ProSitePatterns PS00856 Guanylate kinase-like signature. 42 59 - T 26-04-2017 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 A4V04_RS06965 cba2dae122399f5b54ebf2b4679002b8 210 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 9 185 1.9E-69 T 26-04-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 A4V04_RS06965 cba2dae122399f5b54ebf2b4679002b8 210 SUPERFAMILY SSF52540 6 190 1.89E-61 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06965 cba2dae122399f5b54ebf2b4679002b8 210 Gene3D G3DSA:3.40.50.300 5 23 4.2E-45 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06965 cba2dae122399f5b54ebf2b4679002b8 210 Gene3D G3DSA:3.40.50.300 90 201 4.2E-45 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06965 cba2dae122399f5b54ebf2b4679002b8 210 Gene3D G3DSA:3.40.50.300 24 48 4.5E-5 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06965 cba2dae122399f5b54ebf2b4679002b8 210 Gene3D G3DSA:3.30.63.10 49 89 7.7E-25 T 26-04-2017 A4V04_RS06965 cba2dae122399f5b54ebf2b4679002b8 210 Hamap MF_00328 Guanylate kinase [gmk]. 6 189 35.076 T 26-04-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 A4V04_RS06965 cba2dae122399f5b54ebf2b4679002b8 210 Pfam PF00625 Guanylate kinase 11 184 1.2E-43 T 26-04-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit A4V04_RS06965 cba2dae122399f5b54ebf2b4679002b8 210 SMART SM00072 7 189 5.4E-51 T 26-04-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit A4V04_RS06020 7419a0ba7378d12512959fe5b66c79ec 791 Pfam PF02421 Ferrous iron transport protein B 6 162 3.2E-68 T 26-04-2017 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 A4V04_RS06020 7419a0ba7378d12512959fe5b66c79ec 791 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 164 2.4E-13 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS06020 7419a0ba7378d12512959fe5b66c79ec 791 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 28 46 2.0E-7 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS06020 7419a0ba7378d12512959fe5b66c79ec 791 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 7 27 2.0E-7 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS06020 7419a0ba7378d12512959fe5b66c79ec 791 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 55 70 2.0E-7 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS06020 7419a0ba7378d12512959fe5b66c79ec 791 Pfam PF07670 Nucleoside recognition 355 445 4.8E-15 T 26-04-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A4V04_RS06020 7419a0ba7378d12512959fe5b66c79ec 791 Pfam PF07670 Nucleoside recognition 515 722 6.8E-31 T 26-04-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A4V04_RS06020 7419a0ba7378d12512959fe5b66c79ec 791 Gene3D G3DSA:3.40.50.300 6 170 2.7E-36 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06020 7419a0ba7378d12512959fe5b66c79ec 791 SUPERFAMILY SSF52540 6 172 3.96E-41 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06020 7419a0ba7378d12512959fe5b66c79ec 791 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 11 718 3.6E-192 T 26-04-2017 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 A4V04_RS06020 7419a0ba7378d12512959fe5b66c79ec 791 Pfam PF07664 Ferrous iron transport protein B C terminus 458 510 2.6E-22 T 26-04-2017 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 A4V04_RS04595 1a365c1393a46029fc527b9b2e6e278e 240 Pfam PF01168 Alanine racemase, N-terminal domain 19 234 7.8E-29 T 26-04-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS04595 1a365c1393a46029fc527b9b2e6e278e 240 PIRSF PIRSF004848 4 240 2.1E-71 T 26-04-2017 IPR011078 Uncharacterised protein family UPF0001 A4V04_RS04595 1a365c1393a46029fc527b9b2e6e278e 240 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 14 234 1.6E-72 T 26-04-2017 IPR011078 Uncharacterised protein family UPF0001 A4V04_RS04595 1a365c1393a46029fc527b9b2e6e278e 240 Gene3D G3DSA:3.20.20.10 8 238 1.1E-81 T 26-04-2017 IPR029066 PLP-binding barrel A4V04_RS04595 1a365c1393a46029fc527b9b2e6e278e 240 SUPERFAMILY SSF51419 8 232 9.03E-73 T 26-04-2017 IPR029066 PLP-binding barrel A4V04_RS08330 f26d776bd4992dcf9572698dee63f038 405 Pfam PF01546 Peptidase family M20/M25/M40 101 398 1.1E-16 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS08330 f26d776bd4992dcf9572698dee63f038 405 Gene3D G3DSA:3.40.630.10 30 204 5.7E-43 T 26-04-2017 A4V04_RS08330 f26d776bd4992dcf9572698dee63f038 405 Gene3D G3DSA:3.40.630.10 314 403 5.7E-43 T 26-04-2017 A4V04_RS08330 f26d776bd4992dcf9572698dee63f038 405 SUPERFAMILY SSF53187 325 402 9.14E-38 T 26-04-2017 A4V04_RS08330 f26d776bd4992dcf9572698dee63f038 405 SUPERFAMILY SSF53187 30 213 9.14E-38 T 26-04-2017 A4V04_RS08330 f26d776bd4992dcf9572698dee63f038 405 PIRSF PIRSF037238 24 402 6.5E-95 T 26-04-2017 IPR017150 Peptidase M20, glutamate carboxypeptidase A4V04_RS08330 f26d776bd4992dcf9572698dee63f038 405 Gene3D G3DSA:3.30.70.360 205 311 1.5E-25 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS08330 f26d776bd4992dcf9572698dee63f038 405 SUPERFAMILY SSF55031 204 311 2.24E-23 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS08330 f26d776bd4992dcf9572698dee63f038 405 Pfam PF07687 Peptidase dimerisation domain 202 300 1.2E-18 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS11700 5faf6b5a128d64d0c5d4693c5e615514 326 Gene3D G3DSA:1.10.600.10 8 325 2.0E-97 T 26-04-2017 IPR008949 Isoprenoid synthase domain A4V04_RS11700 5faf6b5a128d64d0c5d4693c5e615514 326 SUPERFAMILY SSF48576 7 325 9.6E-95 T 26-04-2017 IPR008949 Isoprenoid synthase domain A4V04_RS11700 5faf6b5a128d64d0c5d4693c5e615514 326 Pfam PF00348 Polyprenyl synthetase 36 280 3.0E-75 T 26-04-2017 IPR000092 Polyprenyl synthetase GO:0008299 A4V04_RS11700 5faf6b5a128d64d0c5d4693c5e615514 326 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 86 100 - T 26-04-2017 IPR000092 Polyprenyl synthetase GO:0008299 A4V04_RS11700 5faf6b5a128d64d0c5d4693c5e615514 326 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 208 220 - T 26-04-2017 IPR000092 Polyprenyl synthetase GO:0008299 A4V04_RS09745 66fd76a90f14518a728e0aeb9f4916c5 477 Gene3D G3DSA:1.10.40.30 416 460 9.1E-11 T 26-04-2017 A4V04_RS09745 66fd76a90f14518a728e0aeb9f4916c5 477 PRINTS PR00149 Fumarate lyase superfamily signature 176 194 6.6E-10 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09745 66fd76a90f14518a728e0aeb9f4916c5 477 PRINTS PR00149 Fumarate lyase superfamily signature 131 149 6.6E-10 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09745 66fd76a90f14518a728e0aeb9f4916c5 477 PRINTS PR00149 Fumarate lyase superfamily signature 312 328 6.6E-10 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS09745 66fd76a90f14518a728e0aeb9f4916c5 477 SUPERFAMILY SSF48557 1 458 1.13E-87 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS09745 66fd76a90f14518a728e0aeb9f4916c5 477 Gene3D G3DSA:1.10.275.10 1 135 1.1E-47 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS09745 66fd76a90f14518a728e0aeb9f4916c5 477 Gene3D G3DSA:1.20.200.10 136 415 3.0E-51 T 26-04-2017 A4V04_RS09745 66fd76a90f14518a728e0aeb9f4916c5 477 Pfam PF00206 Lyase 9 328 2.2E-59 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS09745 66fd76a90f14518a728e0aeb9f4916c5 477 Pfam PF10415 Fumarase C C-terminus 406 458 1.4E-11 T 26-04-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS03710 8dd3a40322fd367396b23912c35c81f5 353 Gene3D G3DSA:3.40.50.970 35 324 5.0E-66 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS03710 8dd3a40322fd367396b23912c35c81f5 353 SUPERFAMILY SSF52518 34 308 3.72E-66 T 26-04-2017 IPR029061 Thiamin diphosphate-binding fold A4V04_RS03710 8dd3a40322fd367396b23912c35c81f5 353 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 75 242 1.9E-19 T 26-04-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 SUPERFAMILY SSF82693 38 131 8.2E-28 T 26-04-2017 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 SUPERFAMILY SSF82693 136 182 9.94E-24 T 26-04-2017 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 SUPERFAMILY SSF82693 274 330 9.94E-24 T 26-04-2017 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 1.4E-110 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 1.4E-110 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.4E-110 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.4E-110 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 1.4E-110 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 1.4E-110 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.4E-110 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 1.4E-110 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.4E-110 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 Gene3D G3DSA:1.10.3850.10 281 498 8.2E-55 T 26-04-2017 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 Gene3D G3DSA:1.10.3850.10 813 1026 3.5E-53 T 26-04-2017 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 Gene3D G3DSA:3.30.70.1430 38 137 9.2E-34 T 26-04-2017 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 SUPERFAMILY SSF82866 303 497 1.96E-46 T 26-04-2017 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 Gene3D G3DSA:3.30.70.1430 566 669 1.8E-34 T 26-04-2017 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 Gene3D G3DSA:3.30.2090.10 721 809 8.4E-26 T 26-04-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 Gene3D G3DSA:3.30.2090.10 183 275 8.5E-23 T 26-04-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 Pfam PF00873 AcrB/AcrD/AcrF family 1 1024 0.0 T 26-04-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 SUPERFAMILY SSF82714 721 807 2.49E-21 T 26-04-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 SUPERFAMILY SSF82714 183 272 9.94E-21 T 26-04-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 SUPERFAMILY SSF82866 805 1027 8.63E-42 T 26-04-2017 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1041 0.0 T 26-04-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 A4V04_RS08275 ff734b729ccdb3af6aa4bb757b65e34a 1054 SUPERFAMILY SSF82693 564 669 6.8E-29 T 26-04-2017 A4V04_RS12620 dc443e7dbe30539beb6b8d304126706c 417 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 414 2.9E-178 T 26-04-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS12620 dc443e7dbe30539beb6b8d304126706c 417 Gene3D G3DSA:3.65.10.10 220 416 1.2E-60 T 26-04-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 A4V04_RS12620 dc443e7dbe30539beb6b8d304126706c 417 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 415 46.991 T 26-04-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS12620 dc443e7dbe30539beb6b8d304126706c 417 Gene3D G3DSA:3.65.10.10 21 219 1.1E-68 T 26-04-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 A4V04_RS12620 dc443e7dbe30539beb6b8d304126706c 417 SUPERFAMILY SSF55205 2 416 1.44E-142 T 26-04-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A4V04_RS12620 dc443e7dbe30539beb6b8d304126706c 417 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 405 6.7E-109 T 26-04-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 A4V04_RS00385 5b7f93fc9b0dae11239c9095b94c2e76 62 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 19 51 1.7E-8 T 26-04-2017 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 A4V04_RS10360 382e956552ebc7be139ca0da04ab3a47 526 SUPERFAMILY SSF56425 332 473 1.15E-22 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10360 382e956552ebc7be139ca0da04ab3a47 526 Gene3D G3DSA:3.50.50.60 469 524 9.8E-62 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10360 382e956552ebc7be139ca0da04ab3a47 526 Gene3D G3DSA:3.50.50.60 33 302 9.8E-62 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10360 382e956552ebc7be139ca0da04ab3a47 526 Gene3D G3DSA:3.90.700.10 329 462 1.9E-25 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10360 382e956552ebc7be139ca0da04ab3a47 526 Pfam PF00890 FAD binding domain 45 504 2.0E-47 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10360 382e956552ebc7be139ca0da04ab3a47 526 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 489 504 6.2E-5 T 26-04-2017 A4V04_RS10360 382e956552ebc7be139ca0da04ab3a47 526 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 45 67 6.2E-5 T 26-04-2017 A4V04_RS10360 382e956552ebc7be139ca0da04ab3a47 526 SUPERFAMILY SSF51905 467 523 4.12E-38 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10360 382e956552ebc7be139ca0da04ab3a47 526 SUPERFAMILY SSF51905 37 303 4.12E-38 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10705 55eeaacdeccc68da8566262f05ab669b 669 SUPERFAMILY SSF52540 444 539 9.0E-35 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10705 55eeaacdeccc68da8566262f05ab669b 669 SUPERFAMILY SSF52540 150 381 9.0E-35 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10705 55eeaacdeccc68da8566262f05ab669b 669 SMART SM00490 433 530 2.9E-6 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS10705 55eeaacdeccc68da8566262f05ab669b 669 Gene3D G3DSA:3.40.50.300 137 321 3.2E-30 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10705 55eeaacdeccc68da8566262f05ab669b 669 Pfam PF00271 Helicase conserved C-terminal domain 456 529 3.2E-8 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS10705 55eeaacdeccc68da8566262f05ab669b 669 TIGRFAM TIGR00595 priA: primosomal protein N' 157 667 6.0E-164 T 26-04-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 A4V04_RS10705 55eeaacdeccc68da8566262f05ab669b 669 Gene3D G3DSA:3.40.50.300 434 574 6.4E-30 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10705 55eeaacdeccc68da8566262f05ab669b 669 Gene3D G3DSA:3.40.50.300 348 369 6.4E-30 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10705 55eeaacdeccc68da8566262f05ab669b 669 Hamap MF_00983 Probable primosomal protein N' [priA]. 8 669 21.641 T 26-04-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 A4V04_RS10705 55eeaacdeccc68da8566262f05ab669b 669 SMART SM00487 133 335 2.3E-17 T 26-04-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4V04_RS10705 55eeaacdeccc68da8566262f05ab669b 669 Pfam PF04851 Type III restriction enzyme, res subunit 138 299 1.1E-12 T 26-04-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4V04_RS06775 8a07829034b494f332b1e3950e0a0b79 222 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 8 218 7.3E-75 T 26-04-2017 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria A4V04_RS06775 8a07829034b494f332b1e3950e0a0b79 222 Pfam PF03379 CcmB protein 6 219 1.3E-75 T 26-04-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06775 8a07829034b494f332b1e3950e0a0b79 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 134 157 2.6E-61 T 26-04-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06775 8a07829034b494f332b1e3950e0a0b79 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 195 218 2.6E-61 T 26-04-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06775 8a07829034b494f332b1e3950e0a0b79 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 29 50 2.6E-61 T 26-04-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06775 8a07829034b494f332b1e3950e0a0b79 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 78 101 2.6E-61 T 26-04-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06775 8a07829034b494f332b1e3950e0a0b79 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 55 72 2.6E-61 T 26-04-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06775 8a07829034b494f332b1e3950e0a0b79 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 103 121 2.6E-61 T 26-04-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06775 8a07829034b494f332b1e3950e0a0b79 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 157 176 2.6E-61 T 26-04-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS06775 8a07829034b494f332b1e3950e0a0b79 222 PIRSF PIRSF002764 1 222 1.4E-76 T 26-04-2017 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria A4V04_RS12920 d6c7e4fb0cd428cf9fbf4810af225303 251 Pfam PF00005 ABC transporter 19 160 1.0E-28 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS12920 d6c7e4fb0cd428cf9fbf4810af225303 251 SUPERFAMILY SSF52540 4 223 3.41E-50 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12920 d6c7e4fb0cd428cf9fbf4810af225303 251 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS12920 d6c7e4fb0cd428cf9fbf4810af225303 251 Gene3D G3DSA:3.40.50.300 4 227 1.1E-54 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12920 d6c7e4fb0cd428cf9fbf4810af225303 251 SMART SM00382 28 209 1.2E-9 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS10205 a0b220def7dc9495b25036d13af17215 349 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 65 2.9E-9 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS10205 a0b220def7dc9495b25036d13af17215 349 SUPERFAMILY SSF53850 97 302 2.17E-18 T 26-04-2017 A4V04_RS10205 a0b220def7dc9495b25036d13af17215 349 SUPERFAMILY SSF46785 9 87 1.32E-13 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10205 a0b220def7dc9495b25036d13af17215 349 Gene3D G3DSA:3.40.190.10 182 269 9.7E-6 T 26-04-2017 A4V04_RS10205 a0b220def7dc9495b25036d13af17215 349 Pfam PF03466 LysR substrate binding domain 98 298 2.4E-13 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS10205 a0b220def7dc9495b25036d13af17215 349 Gene3D G3DSA:1.10.10.10 9 88 2.0E-15 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10205 a0b220def7dc9495b25036d13af17215 349 Gene3D G3DSA:3.40.190.10 100 181 4.0E-14 T 26-04-2017 A4V04_RS05320 61a6146e1ca337183587d50b9000d8e1 516 PRINTS PR01806 Virulence factor MviN signature 52 68 4.2E-72 T 26-04-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ A4V04_RS05320 61a6146e1ca337183587d50b9000d8e1 516 PRINTS PR01806 Virulence factor MviN signature 360 379 4.2E-72 T 26-04-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ A4V04_RS05320 61a6146e1ca337183587d50b9000d8e1 516 PRINTS PR01806 Virulence factor MviN signature 157 178 4.2E-72 T 26-04-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ A4V04_RS05320 61a6146e1ca337183587d50b9000d8e1 516 PRINTS PR01806 Virulence factor MviN signature 33 52 4.2E-72 T 26-04-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ A4V04_RS05320 61a6146e1ca337183587d50b9000d8e1 516 PRINTS PR01806 Virulence factor MviN signature 412 429 4.2E-72 T 26-04-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ A4V04_RS05320 61a6146e1ca337183587d50b9000d8e1 516 PRINTS PR01806 Virulence factor MviN signature 133 157 4.2E-72 T 26-04-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ A4V04_RS05320 61a6146e1ca337183587d50b9000d8e1 516 PRINTS PR01806 Virulence factor MviN signature 262 288 4.2E-72 T 26-04-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ A4V04_RS05320 61a6146e1ca337183587d50b9000d8e1 516 Pfam PF03023 MviN-like protein 28 472 2.6E-125 T 26-04-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ A4V04_RS05320 61a6146e1ca337183587d50b9000d8e1 516 PIRSF PIRSF002869 1 513 2.9E-148 T 26-04-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ A4V04_RS05320 61a6146e1ca337183587d50b9000d8e1 516 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 504 6.6E-133 T 26-04-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ A4V04_RS05195 140ad7d9c19dffafbfc94401937513e0 782 Pfam PF07670 Nucleoside recognition 515 721 1.9E-30 T 26-04-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A4V04_RS05195 140ad7d9c19dffafbfc94401937513e0 782 Pfam PF07670 Nucleoside recognition 354 445 2.3E-12 T 26-04-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A4V04_RS05195 140ad7d9c19dffafbfc94401937513e0 782 Gene3D G3DSA:3.40.50.300 5 170 5.0E-36 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05195 140ad7d9c19dffafbfc94401937513e0 782 SUPERFAMILY SSF52540 6 176 1.24E-41 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05195 140ad7d9c19dffafbfc94401937513e0 782 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 11 717 3.3E-194 T 26-04-2017 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 A4V04_RS05195 140ad7d9c19dffafbfc94401937513e0 782 Pfam PF02421 Ferrous iron transport protein B 6 163 7.8E-65 T 26-04-2017 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 A4V04_RS05195 140ad7d9c19dffafbfc94401937513e0 782 Pfam PF07664 Ferrous iron transport protein B C terminus 458 510 1.3E-22 T 26-04-2017 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 A4V04_RS05195 140ad7d9c19dffafbfc94401937513e0 782 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 126 4.8E-12 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS05195 140ad7d9c19dffafbfc94401937513e0 782 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 55 70 7.8E-5 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS05195 140ad7d9c19dffafbfc94401937513e0 782 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 7 27 7.8E-5 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS12505 8baa9010c088c194657dbb542b124ef4 512 Pfam PF07669 Eco57I restriction-modification methylase 182 281 3.6E-35 T 26-04-2017 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 A4V04_RS12505 8baa9010c088c194657dbb542b124ef4 512 SUPERFAMILY SSF53335 23 113 4.16E-29 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS12505 8baa9010c088c194657dbb542b124ef4 512 SUPERFAMILY SSF53335 175 316 4.16E-29 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS12505 8baa9010c088c194657dbb542b124ef4 512 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 184 196 3.5E-9 T 26-04-2017 A4V04_RS12505 8baa9010c088c194657dbb542b124ef4 512 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 25 41 3.5E-9 T 26-04-2017 A4V04_RS12505 8baa9010c088c194657dbb542b124ef4 512 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 53 67 3.5E-9 T 26-04-2017 A4V04_RS12505 8baa9010c088c194657dbb542b124ef4 512 Gene3D G3DSA:3.40.50.150 156 303 8.0E-22 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS12505 8baa9010c088c194657dbb542b124ef4 512 Gene3D G3DSA:3.40.50.150 27 110 8.0E-22 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS12505 8baa9010c088c194657dbb542b124ef4 512 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 187 193 - T 26-04-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4V04_RS11780 7849730421c7c0eab807cb973eb067be 673 Pfam PF03050 Transposase IS66 family 258 585 1.4E-29 T 26-04-2017 IPR004291 Transposase, IS66 A4V04_RS12395 5a9b46a8b753f936af68fd749901e395 359 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 5 357 2.2E-128 T 26-04-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 A4V04_RS12395 5a9b46a8b753f936af68fd749901e395 359 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 4 358 38.484 T 26-04-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 A4V04_RS12395 5a9b46a8b753f936af68fd749901e395 359 Pfam PF03054 tRNA methyl transferase 5 357 5.3E-131 T 26-04-2017 A4V04_RS12395 5a9b46a8b753f936af68fd749901e395 359 Gene3D G3DSA:2.30.30.280 210 278 1.4E-32 T 26-04-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 A4V04_RS12395 5a9b46a8b753f936af68fd749901e395 359 SUPERFAMILY SSF52402 4 241 3.77E-57 T 26-04-2017 A4V04_RS12395 5a9b46a8b753f936af68fd749901e395 359 Gene3D G3DSA:3.40.50.620 3 208 6.9E-94 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS12395 5a9b46a8b753f936af68fd749901e395 359 Gene3D G3DSA:2.40.30.10 280 359 3.4E-24 T 26-04-2017 A4V04_RS13080 83f3eeab560ffc83fddc2940b12915c9 279 Gene3D G3DSA:3.90.1170.20 5 128 3.6E-26 T 26-04-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A4V04_RS13080 83f3eeab560ffc83fddc2940b12915c9 279 TIGRFAM TIGR01334 modD: modD protein 3 275 1.6E-69 T 26-04-2017 IPR006242 Putative pyrophosphorylase ModD GO:0016763 A4V04_RS13080 83f3eeab560ffc83fddc2940b12915c9 279 SUPERFAMILY SSF51690 106 275 2.0E-40 T 26-04-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A4V04_RS13080 83f3eeab560ffc83fddc2940b12915c9 279 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 104 2.8E-17 T 26-04-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A4V04_RS13080 83f3eeab560ffc83fddc2940b12915c9 279 SUPERFAMILY SSF54675 2 105 9.03E-20 T 26-04-2017 A4V04_RS13080 83f3eeab560ffc83fddc2940b12915c9 279 Gene3D G3DSA:3.20.20.70 129 264 5.3E-33 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS13080 83f3eeab560ffc83fddc2940b12915c9 279 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 109 273 3.5E-30 T 26-04-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A4V04_RS13080 83f3eeab560ffc83fddc2940b12915c9 279 PIRSF PIRSF006250 1 278 9.1E-63 T 26-04-2017 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 A4V04_RS01580 7097d5ffb5d16f2fe2114c0166456906 565 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 146 155 - T 26-04-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A4V04_RS01580 7097d5ffb5d16f2fe2114c0166456906 565 Gene3D G3DSA:3.40.630.10 444 514 1.0E-17 T 26-04-2017 A4V04_RS01580 7097d5ffb5d16f2fe2114c0166456906 565 Gene3D G3DSA:3.40.630.10 62 166 1.0E-17 T 26-04-2017 A4V04_RS01580 7097d5ffb5d16f2fe2114c0166456906 565 Gene3D G3DSA:3.40.630.10 221 317 1.0E-17 T 26-04-2017 A4V04_RS01580 7097d5ffb5d16f2fe2114c0166456906 565 SUPERFAMILY SSF53187 443 533 2.1E-17 T 26-04-2017 A4V04_RS01580 7097d5ffb5d16f2fe2114c0166456906 565 SUPERFAMILY SSF53187 221 329 2.1E-17 T 26-04-2017 A4V04_RS01580 7097d5ffb5d16f2fe2114c0166456906 565 SUPERFAMILY SSF53187 60 163 2.1E-17 T 26-04-2017 A4V04_RS06305 d198bee6cb65ed4be03fc2aaac4787bf 118 Gene3D G3DSA:2.30.30.110 6 113 5.2E-30 T 26-04-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A4V04_RS06305 d198bee6cb65ed4be03fc2aaac4787bf 118 SUPERFAMILY SSF50118 5 114 1.0E-25 T 26-04-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A4V04_RS06305 d198bee6cb65ed4be03fc2aaac4787bf 118 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 7 109 4.0E-19 T 26-04-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 A4V04_RS05815 c8ff3cec9004791a1bb8e326076bbcfe 141 Gene3D G3DSA:2.40.50.140 82 125 1.0E-4 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS05815 c8ff3cec9004791a1bb8e326076bbcfe 141 Pfam PF01957 NfeD-like C-terminal, partner-binding 7 112 8.6E-8 T 26-04-2017 IPR002810 NfeD-like, C-terminal domain A4V04_RS09845 cb1e585bed7dd28c63a6aeef832f52f9 441 Gene3D G3DSA:2.40.128.130 144 439 8.5E-57 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS09845 cb1e585bed7dd28c63a6aeef832f52f9 441 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 30 441 3.6E-52 T 26-04-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 A4V04_RS09845 cb1e585bed7dd28c63a6aeef832f52f9 441 Gene3D G3DSA:2.160.20.20 1 84 4.1E-6 T 26-04-2017 IPR012332 P22 tailspike C-terminal domain-like A4V04_RS09845 cb1e585bed7dd28c63a6aeef832f52f9 441 PRINTS PR01484 Pertactin virulence factor family signature 396 421 1.9E-9 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS09845 cb1e585bed7dd28c63a6aeef832f52f9 441 PRINTS PR01484 Pertactin virulence factor family signature 151 169 1.9E-9 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS09845 cb1e585bed7dd28c63a6aeef832f52f9 441 PRINTS PR01484 Pertactin virulence factor family signature 310 327 1.9E-9 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS09845 cb1e585bed7dd28c63a6aeef832f52f9 441 PRINTS PR01484 Pertactin virulence factor family signature 358 379 1.9E-9 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS09845 cb1e585bed7dd28c63a6aeef832f52f9 441 PRINTS PR01484 Pertactin virulence factor family signature 329 352 1.9E-9 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS09845 cb1e585bed7dd28c63a6aeef832f52f9 441 Pfam PF03797 Autotransporter beta-domain 199 425 9.1E-39 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS09845 cb1e585bed7dd28c63a6aeef832f52f9 441 SUPERFAMILY SSF103515 156 441 2.88E-36 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS09845 cb1e585bed7dd28c63a6aeef832f52f9 441 SMART SM00869 175 430 1.0E-30 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS07085 aa2efd9ac91e5de56ccdac6d3c31d8db 415 Gene3D G3DSA:3.30.70.360 199 299 5.3E-18 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS07085 aa2efd9ac91e5de56ccdac6d3c31d8db 415 SUPERFAMILY SSF55031 199 302 7.92E-16 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS07085 aa2efd9ac91e5de56ccdac6d3c31d8db 415 Gene3D G3DSA:3.40.630.10 329 401 3.9E-46 T 26-04-2017 A4V04_RS07085 aa2efd9ac91e5de56ccdac6d3c31d8db 415 Gene3D G3DSA:3.40.630.10 41 193 3.9E-46 T 26-04-2017 A4V04_RS07085 aa2efd9ac91e5de56ccdac6d3c31d8db 415 Pfam PF07687 Peptidase dimerisation domain 197 297 9.9E-16 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS07085 aa2efd9ac91e5de56ccdac6d3c31d8db 415 SUPERFAMILY SSF53187 319 405 1.15E-44 T 26-04-2017 A4V04_RS07085 aa2efd9ac91e5de56ccdac6d3c31d8db 415 SUPERFAMILY SSF53187 41 211 1.15E-44 T 26-04-2017 A4V04_RS07085 aa2efd9ac91e5de56ccdac6d3c31d8db 415 Pfam PF01546 Peptidase family M20/M25/M40 96 391 4.9E-17 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS05965 71b94d24daf1463b514995fdb119b5cc 382 Pfam PF01546 Peptidase family M20/M25/M40 67 374 5.8E-40 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS05965 71b94d24daf1463b514995fdb119b5cc 382 Gene3D G3DSA:3.30.70.360 191 291 5.8E-30 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS05965 71b94d24daf1463b514995fdb119b5cc 382 Pfam PF07687 Peptidase dimerisation domain 178 283 1.0E-23 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS05965 71b94d24daf1463b514995fdb119b5cc 382 Gene3D G3DSA:3.40.630.10 9 190 3.3E-66 T 26-04-2017 A4V04_RS05965 71b94d24daf1463b514995fdb119b5cc 382 Gene3D G3DSA:3.40.630.10 319 377 3.3E-66 T 26-04-2017 A4V04_RS05965 71b94d24daf1463b514995fdb119b5cc 382 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 7 378 44.315 T 26-04-2017 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 A4V04_RS05965 71b94d24daf1463b514995fdb119b5cc 382 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 11 376 5.3E-134 T 26-04-2017 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 A4V04_RS05965 71b94d24daf1463b514995fdb119b5cc 382 SUPERFAMILY SSF53187 9 181 2.6E-58 T 26-04-2017 A4V04_RS05965 71b94d24daf1463b514995fdb119b5cc 382 SUPERFAMILY SSF53187 295 377 2.6E-58 T 26-04-2017 A4V04_RS05965 71b94d24daf1463b514995fdb119b5cc 382 SUPERFAMILY SSF55031 182 291 5.89E-26 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS07030 ff14b391dfb7ec52a70580b16807266e 390 Gene3D G3DSA:1.20.1250.20 198 383 6.4E-13 T 26-04-2017 A4V04_RS07030 ff14b391dfb7ec52a70580b16807266e 390 Gene3D G3DSA:1.20.1250.20 5 191 4.6E-18 T 26-04-2017 A4V04_RS07030 ff14b391dfb7ec52a70580b16807266e 390 SUPERFAMILY SSF103473 6 385 5.62E-42 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS07030 ff14b391dfb7ec52a70580b16807266e 390 Pfam PF07690 Major Facilitator Superfamily 10 341 2.2E-22 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS03615 c8991512d8260109fea234fa17226f60 174 SUPERFAMILY SSF50346 104 171 2.83E-17 T 26-04-2017 IPR011033 PRC-barrel-like A4V04_RS03615 c8991512d8260109fea234fa17226f60 174 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 12 171 9.4E-41 T 26-04-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A4V04_RS03615 c8991512d8260109fea234fa17226f60 174 Gene3D G3DSA:2.30.30.240 104 172 2.3E-22 T 26-04-2017 A4V04_RS03615 c8991512d8260109fea234fa17226f60 174 Gene3D G3DSA:2.40.30.60 4 96 5.8E-21 T 26-04-2017 IPR002676 RimM protein GO:0006364 A4V04_RS03615 c8991512d8260109fea234fa17226f60 174 SUPERFAMILY SSF50447 11 88 1.48E-14 T 26-04-2017 IPR009000 Translation protein, beta-barrel domain A4V04_RS03615 c8991512d8260109fea234fa17226f60 174 Pfam PF01782 RimM N-terminal domain 14 87 1.1E-17 T 26-04-2017 IPR002676 RimM protein GO:0006364 A4V04_RS03615 c8991512d8260109fea234fa17226f60 174 Pfam PF05239 PRC-barrel domain 100 168 1.8E-7 T 26-04-2017 IPR027275 PRC-barrel domain A4V04_RS03615 c8991512d8260109fea234fa17226f60 174 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 11 173 20.574 T 26-04-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A4V04_RS01855 2a1261c4b31f91f4feb49779a387a14a 662 Pfam PF12696 TraM recognition site of TraD and TraG 470 588 1.7E-12 T 26-04-2017 IPR032689 TraD/TraG, TraM recognition site A4V04_RS01855 2a1261c4b31f91f4feb49779a387a14a 662 Gene3D G3DSA:3.40.50.300 154 242 2.1E-33 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01855 2a1261c4b31f91f4feb49779a387a14a 662 Gene3D G3DSA:3.40.50.300 417 626 2.1E-33 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01855 2a1261c4b31f91f4feb49779a387a14a 662 SUPERFAMILY SSF52540 371 625 6.9E-35 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01855 2a1261c4b31f91f4feb49779a387a14a 662 SUPERFAMILY SSF52540 145 287 6.9E-35 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01855 2a1261c4b31f91f4feb49779a387a14a 662 TIGRFAM TIGR03743 SXT_TraD: conjugative coupling factor TraD, SXT/TOL subfamily 12 618 8.0E-158 T 26-04-2017 IPR022458 Conjugative coupling factor TraG/TraD A4V04_RS06035 096b40b4bcb33dd1223e285d69101d92 368 PRINTS PR00184 Neisseria sp. porin signature 224 244 3.6E-6 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS06035 096b40b4bcb33dd1223e285d69101d92 368 PRINTS PR00184 Neisseria sp. porin signature 155 172 3.6E-6 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS06035 096b40b4bcb33dd1223e285d69101d92 368 PRINTS PR00184 Neisseria sp. porin signature 54 79 3.6E-6 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS06035 096b40b4bcb33dd1223e285d69101d92 368 Pfam PF13609 Gram-negative porin 9 340 5.7E-36 T 26-04-2017 A4V04_RS06035 096b40b4bcb33dd1223e285d69101d92 368 SUPERFAMILY SSF56935 22 368 2.98E-51 T 26-04-2017 A4V04_RS06035 096b40b4bcb33dd1223e285d69101d92 368 Gene3D G3DSA:2.40.160.10 23 368 9.9E-62 T 26-04-2017 IPR023614 Porin domain A4V04_RS05960 a692fde69977375df91dbf80f2105c85 268 Gene3D G3DSA:2.160.10.10 86 250 1.9E-62 T 26-04-2017 A4V04_RS05960 a692fde69977375df91dbf80f2105c85 268 SUPERFAMILY SSF51161 3 252 6.79E-76 T 26-04-2017 IPR011004 Trimeric LpxA-like A4V04_RS05960 a692fde69977375df91dbf80f2105c85 268 Gene3D G3DSA:1.10.166.10 2 66 2.8E-23 T 26-04-2017 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 A4V04_RS05960 a692fde69977375df91dbf80f2105c85 268 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 171 205 2.1E-13 T 26-04-2017 IPR001451 Hexapeptide repeat A4V04_RS05960 a692fde69977375df91dbf80f2105c85 268 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 5 65 4.8E-21 T 26-04-2017 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 A4V04_RS05960 a692fde69977375df91dbf80f2105c85 268 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 4 267 6.9E-137 T 26-04-2017 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 A4V04_RS05960 a692fde69977375df91dbf80f2105c85 268 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 128 162 9.0E-6 T 26-04-2017 IPR001451 Hexapeptide repeat A4V04_RS05960 a692fde69977375df91dbf80f2105c85 268 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 1 268 55.053 T 26-04-2017 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 A4V04_RS08095 509b75be9592abe060876d9bf274448c 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 259 3.6E-45 T 26-04-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4V04_RS08095 509b75be9592abe060876d9bf274448c 260 SUPERFAMILY SSF53850 1 259 6.52E-55 T 26-04-2017 A4V04_RS08095 509b75be9592abe060876d9bf274448c 260 SMART SM00079 37 257 0.0081 T 26-04-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A4V04_RS08095 509b75be9592abe060876d9bf274448c 260 Gene3D G3DSA:3.40.190.10 222 259 2.9E-33 T 26-04-2017 A4V04_RS08095 509b75be9592abe060876d9bf274448c 260 Gene3D G3DSA:3.40.190.10 33 115 2.9E-33 T 26-04-2017 A4V04_RS08095 509b75be9592abe060876d9bf274448c 260 Gene3D G3DSA:3.40.190.10 116 221 1.1E-7 T 26-04-2017 A4V04_RS08095 509b75be9592abe060876d9bf274448c 260 SMART SM00062 37 260 5.7E-39 T 26-04-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4V04_RS01765 74f822a1df9a7fca1a0053841507e5fd 280 SUPERFAMILY SSF52833 138 242 4.14E-11 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS01765 74f822a1df9a7fca1a0053841507e5fd 280 Gene3D G3DSA:3.40.30.10 147 234 4.3E-10 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS01765 74f822a1df9a7fca1a0053841507e5fd 280 Pfam PF13728 F plasmid transfer operon protein 45 247 9.7E-52 T 26-04-2017 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 SUPERFAMILY SSF81665 202 263 8.76E-17 T 26-04-2017 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 SUPERFAMILY SSF81665 360 446 8.76E-17 T 26-04-2017 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 309 323 2.8E-24 T 26-04-2017 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 685 697 2.8E-24 T 26-04-2017 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 661 680 2.8E-24 T 26-04-2017 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 609 619 2.8E-24 T 26-04-2017 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 460 474 2.8E-24 T 26-04-2017 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 SUPERFAMILY SSF56784 520 761 1.37E-48 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 SUPERFAMILY SSF56784 458 478 1.37E-48 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 232 745 3.1E-85 T 26-04-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 194 764 1.7E-119 T 26-04-2017 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 Pfam PF00702 haloacid dehalogenase-like hydrolase 458 675 2.6E-35 T 26-04-2017 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 209 764 9.9E-177 T 26-04-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 PRINTS PR00941 Cadmium-transporting ATPase signature 325 341 7.3E-8 T 26-04-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 PRINTS PR00941 Cadmium-transporting ATPase signature 85 106 7.3E-8 T 26-04-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 PRINTS PR00941 Cadmium-transporting ATPase signature 244 264 7.3E-8 T 26-04-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 PRINTS PR00941 Cadmium-transporting ATPase signature 264 280 7.3E-8 T 26-04-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 SUPERFAMILY SSF81653 262 358 8.5E-26 T 26-04-2017 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 SUPERFAMILY SSF55008 66 138 1.02E-11 T 26-04-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 Pfam PF00122 E1-E2 ATPase 230 450 1.5E-69 T 26-04-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 462 468 - T 26-04-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 Gene3D G3DSA:2.70.150.10 209 360 9.1E-30 T 26-04-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 Gene3D G3DSA:3.30.70.100 70 138 3.8E-8 T 26-04-2017 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 Gene3D G3DSA:3.40.1110.10 474 589 5.5E-15 T 26-04-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 Gene3D G3DSA:3.40.50.1000 590 730 4.8E-43 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS04515 5c45253d6f8be145741f8e8d4046df11 771 Gene3D G3DSA:3.40.50.1000 433 473 4.8E-43 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS12055 50cb4f5b0e0821631a0af24f65df4263 320 Pfam PF01795 MraW methylase family 4 309 1.7E-104 T 26-04-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS12055 50cb4f5b0e0821631a0af24f65df4263 320 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 310 36.987 T 26-04-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS12055 50cb4f5b0e0821631a0af24f65df4263 320 SUPERFAMILY SSF53335 214 309 1.77E-39 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS12055 50cb4f5b0e0821631a0af24f65df4263 320 SUPERFAMILY SSF53335 7 112 1.77E-39 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS12055 50cb4f5b0e0821631a0af24f65df4263 320 PIRSF PIRSF004486 1 311 1.6E-98 T 26-04-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS12055 50cb4f5b0e0821631a0af24f65df4263 320 SUPERFAMILY SSF81799 113 214 5.23E-34 T 26-04-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS12055 50cb4f5b0e0821631a0af24f65df4263 320 Gene3D G3DSA:1.10.150.170 111 216 1.7E-37 T 26-04-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS12055 50cb4f5b0e0821631a0af24f65df4263 320 Gene3D G3DSA:3.40.50.150 217 311 6.1E-41 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS12055 50cb4f5b0e0821631a0af24f65df4263 320 Gene3D G3DSA:3.40.50.150 7 109 6.1E-41 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS12055 50cb4f5b0e0821631a0af24f65df4263 320 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 309 2.2E-105 T 26-04-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS11975 47ea8d6419aa7f3697a7b9cc4b0fff0b 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 4.7E-7 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS11975 47ea8d6419aa7f3697a7b9cc4b0fff0b 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 4.7E-7 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS11975 47ea8d6419aa7f3697a7b9cc4b0fff0b 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 68 5.2E-17 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS11975 47ea8d6419aa7f3697a7b9cc4b0fff0b 248 SUPERFAMILY SSF64288 57 238 1.43E-21 T 26-04-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4V04_RS11975 47ea8d6419aa7f3697a7b9cc4b0fff0b 248 SMART SM00866 89 233 6.1E-10 T 26-04-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4V04_RS11975 47ea8d6419aa7f3697a7b9cc4b0fff0b 248 SUPERFAMILY SSF46785 3 70 1.24E-18 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS11975 47ea8d6419aa7f3697a7b9cc4b0fff0b 248 Gene3D G3DSA:1.10.10.10 2 71 1.7E-22 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS11975 47ea8d6419aa7f3697a7b9cc4b0fff0b 248 Gene3D G3DSA:3.40.1410.10 102 236 6.8E-23 T 26-04-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4V04_RS11975 47ea8d6419aa7f3697a7b9cc4b0fff0b 248 Pfam PF07702 UTRA domain 102 232 7.2E-15 T 26-04-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4V04_RS11975 47ea8d6419aa7f3697a7b9cc4b0fff0b 248 SMART SM00345 9 68 3.7E-17 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS12790 35faa8d16bf3f28a1b08b50da5e825d2 806 Pfam PF17092 Penicillin-binding protein OB-like domain 358 461 1.6E-17 T 26-04-2017 IPR031376 Penicillin-binding protein, OB-like domain A4V04_RS12790 35faa8d16bf3f28a1b08b50da5e825d2 806 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 97 749 1.9E-179 T 26-04-2017 A4V04_RS12790 35faa8d16bf3f28a1b08b50da5e825d2 806 Pfam PF00912 Transglycosylase 87 261 3.3E-61 T 26-04-2017 IPR001264 Glycosyl transferase, family 51 A4V04_RS12790 35faa8d16bf3f28a1b08b50da5e825d2 806 Pfam PF00905 Penicillin binding protein transpeptidase domain 464 728 3.5E-35 T 26-04-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4V04_RS12790 35faa8d16bf3f28a1b08b50da5e825d2 806 SUPERFAMILY SSF53955 74 285 1.43E-73 T 26-04-2017 IPR023346 Lysozyme-like domain A4V04_RS12790 35faa8d16bf3f28a1b08b50da5e825d2 806 Gene3D G3DSA:3.40.710.10 458 765 8.9E-124 T 26-04-2017 IPR012338 Beta-lactamase/transpeptidase-like A4V04_RS12790 35faa8d16bf3f28a1b08b50da5e825d2 806 Gene3D G3DSA:3.40.710.10 305 355 8.9E-124 T 26-04-2017 IPR012338 Beta-lactamase/transpeptidase-like A4V04_RS12790 35faa8d16bf3f28a1b08b50da5e825d2 806 Gene3D G3DSA:1.10.3810.10 87 275 9.6E-72 T 26-04-2017 A4V04_RS12790 35faa8d16bf3f28a1b08b50da5e825d2 806 SUPERFAMILY SSF56601 243 265 5.28E-116 T 26-04-2017 IPR012338 Beta-lactamase/transpeptidase-like A4V04_RS12790 35faa8d16bf3f28a1b08b50da5e825d2 806 SUPERFAMILY SSF56601 304 355 5.28E-116 T 26-04-2017 IPR012338 Beta-lactamase/transpeptidase-like A4V04_RS12790 35faa8d16bf3f28a1b08b50da5e825d2 806 SUPERFAMILY SSF56601 458 764 5.28E-116 T 26-04-2017 IPR012338 Beta-lactamase/transpeptidase-like A4V04_RS12790 35faa8d16bf3f28a1b08b50da5e825d2 806 Gene3D G3DSA:2.40.50.140 389 457 2.2E-19 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS05575 c8e1df0b42e43179c709769b3c3b29e1 572 Pfam PF01609 Transposase DDE domain 177 308 2.0E-8 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS00360 a10c197c5bf883ac09b828db75dc4236 370 SUPERFAMILY SSF56672 12 250 4.8E-88 T 26-04-2017 A4V04_RS00360 a10c197c5bf883ac09b828db75dc4236 370 SUPERFAMILY SSF100879 255 354 5.89E-23 T 26-04-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4V04_RS00360 a10c197c5bf883ac09b828db75dc4236 370 Hamap MF_01113 DNA polymerase IV [dinB]. 19 366 36.68 T 26-04-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A4V04_RS00360 a10c197c5bf883ac09b828db75dc4236 370 Pfam PF11799 impB/mucB/samB family C-terminal domain 254 355 8.1E-11 T 26-04-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4V04_RS00360 a10c197c5bf883ac09b828db75dc4236 370 Gene3D G3DSA:3.30.1490.100 258 363 1.4E-25 T 26-04-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4V04_RS00360 a10c197c5bf883ac09b828db75dc4236 370 Gene3D G3DSA:1.10.150.20 183 251 1.7E-24 T 26-04-2017 A4V04_RS00360 a10c197c5bf883ac09b828db75dc4236 370 Gene3D G3DSA:3.30.70.270 83 181 3.8E-30 T 26-04-2017 A4V04_RS00360 a10c197c5bf883ac09b828db75dc4236 370 Pfam PF00817 impB/mucB/samB family 25 171 4.2E-47 T 26-04-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4V04_RS00360 a10c197c5bf883ac09b828db75dc4236 370 Pfam PF11798 IMS family HHH motif 183 214 1.8E-7 T 26-04-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A4V04_RS07740 0298ed05cd1c55006c8bf04bf78932a6 284 Pfam PF11906 Protein of unknown function (DUF3426) 148 282 4.3E-11 T 26-04-2017 IPR021834 Protein of unknown function DUF3426 A4V04_RS11550 5e5be2106d5de9e0ed37659b144a3c84 530 Gene3D G3DSA:3.90.700.10 300 462 2.7E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11550 5e5be2106d5de9e0ed37659b144a3c84 530 SUPERFAMILY SSF51905 34 293 2.6E-40 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11550 5e5be2106d5de9e0ed37659b144a3c84 530 SUPERFAMILY SSF51905 470 526 2.6E-40 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11550 5e5be2106d5de9e0ed37659b144a3c84 530 SUPERFAMILY SSF56425 285 467 1.7E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11550 5e5be2106d5de9e0ed37659b144a3c84 530 Gene3D G3DSA:3.50.50.60 467 526 3.7E-61 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11550 5e5be2106d5de9e0ed37659b144a3c84 530 Gene3D G3DSA:3.50.50.60 33 277 3.7E-61 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11550 5e5be2106d5de9e0ed37659b144a3c84 530 Pfam PF00890 FAD binding domain 44 509 2.8E-54 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS12345 c0de0bd7985f6c65a71884a1fe4326d9 87 SUPERFAMILY SSF50249 1 71 9.14E-27 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS12345 c0de0bd7985f6c65a71884a1fe4326d9 87 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 75 25.828 T 26-04-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A4V04_RS12345 c0de0bd7985f6c65a71884a1fe4326d9 87 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 1.5E-31 T 26-04-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A4V04_RS12345 c0de0bd7985f6c65a71884a1fe4326d9 87 Pfam PF01176 Translation initiation factor 1A / IF-1 8 70 1.5E-25 T 26-04-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 A4V04_RS12345 c0de0bd7985f6c65a71884a1fe4326d9 87 Gene3D G3DSA:2.40.50.140 1 71 8.5E-35 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS05005 748c5db227ce526d4b78a0425f5c3021 443 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 88 114 7.1E-16 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS05005 748c5db227ce526d4b78a0425f5c3021 443 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 14 35 7.1E-16 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS05005 748c5db227ce526d4b78a0425f5c3021 443 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 423 443 7.1E-16 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS05005 748c5db227ce526d4b78a0425f5c3021 443 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 43 62 7.1E-16 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS05005 748c5db227ce526d4b78a0425f5c3021 443 Pfam PF00209 Sodium:neurotransmitter symporter family 151 442 4.0E-30 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS05005 748c5db227ce526d4b78a0425f5c3021 443 Pfam PF00209 Sodium:neurotransmitter symporter family 7 118 4.1E-24 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS05005 748c5db227ce526d4b78a0425f5c3021 443 SUPERFAMILY SSF161070 8 443 1.31E-117 T 26-04-2017 A4V04_RS05785 c14c00544e1e0b7805ec0a803dfea3eb 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 473 2.6E-164 T 26-04-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A4V04_RS05785 c14c00544e1e0b7805ec0a803dfea3eb 488 SMART SM01240 6 473 0.0 T 26-04-2017 A4V04_RS05785 c14c00544e1e0b7805ec0a803dfea3eb 488 Pfam PF00571 CBS domain 148 202 1.0E-8 T 26-04-2017 IPR000644 CBS domain A4V04_RS05785 c14c00544e1e0b7805ec0a803dfea3eb 488 Pfam PF00571 CBS domain 92 138 2.1E-9 T 26-04-2017 IPR000644 CBS domain A4V04_RS05785 c14c00544e1e0b7805ec0a803dfea3eb 488 SMART SM00116 156 204 2.6E-9 T 26-04-2017 IPR000644 CBS domain A4V04_RS05785 c14c00544e1e0b7805ec0a803dfea3eb 488 SMART SM00116 95 142 4.0E-8 T 26-04-2017 IPR000644 CBS domain A4V04_RS05785 c14c00544e1e0b7805ec0a803dfea3eb 488 PIRSF PIRSF000130 1 488 1.7E-203 T 26-04-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4V04_RS05785 c14c00544e1e0b7805ec0a803dfea3eb 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 26-04-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A4V04_RS05785 c14c00544e1e0b7805ec0a803dfea3eb 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 486 85.001 T 26-04-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4V04_RS05785 c14c00544e1e0b7805ec0a803dfea3eb 488 Gene3D G3DSA:3.20.20.70 5 485 2.9E-202 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS05785 c14c00544e1e0b7805ec0a803dfea3eb 488 SUPERFAMILY SSF51412 215 477 5.23E-128 T 26-04-2017 A4V04_RS05785 c14c00544e1e0b7805ec0a803dfea3eb 488 SUPERFAMILY SSF51412 2 89 5.23E-128 T 26-04-2017 A4V04_RS05785 c14c00544e1e0b7805ec0a803dfea3eb 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 454 1.7E-190 T 26-04-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4V04_RS05785 c14c00544e1e0b7805ec0a803dfea3eb 488 SUPERFAMILY SSF54631 92 202 1.83E-27 T 26-04-2017 A4V04_RS00110 8598c885d5be440218ca61348df726c6 330 Pfam PF04126 Cyclophilin-like 214 322 4.2E-10 T 26-04-2017 IPR025658 Cyclophilin TM1367-like domain A4V04_RS00110 8598c885d5be440218ca61348df726c6 330 Gene3D G3DSA:3.40.50.360 28 204 3.7E-12 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS00110 8598c885d5be440218ca61348df726c6 330 SUPERFAMILY SSF52218 58 185 1.93E-12 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS00110 8598c885d5be440218ca61348df726c6 330 Pfam PF12682 Flavodoxin 60 202 3.4E-13 T 26-04-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A4V04_RS00110 8598c885d5be440218ca61348df726c6 330 SUPERFAMILY SSF50891 215 323 1.52E-14 T 26-04-2017 IPR029000 Cyclophilin-like domain A4V04_RS08740 3c46e76a3ab677e153edf41e84d2dbe1 487 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 38 486 33.54 T 26-04-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS08740 3c46e76a3ab677e153edf41e84d2dbe1 487 Gene3D G3DSA:1.10.1390.10 469 485 9.7E-8 T 26-04-2017 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS08740 3c46e76a3ab677e153edf41e84d2dbe1 487 Pfam PF00342 Phosphoglucose isomerase 44 485 4.0E-125 T 26-04-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS08740 3c46e76a3ab677e153edf41e84d2dbe1 487 Gene3D G3DSA:3.40.50.10490 280 468 1.2E-69 T 26-04-2017 A4V04_RS08740 3c46e76a3ab677e153edf41e84d2dbe1 487 Gene3D G3DSA:3.40.50.10490 36 90 1.2E-69 T 26-04-2017 A4V04_RS08740 3c46e76a3ab677e153edf41e84d2dbe1 487 Gene3D G3DSA:3.40.50.10490 103 277 3.8E-60 T 26-04-2017 A4V04_RS08740 3c46e76a3ab677e153edf41e84d2dbe1 487 SUPERFAMILY SSF53697 34 485 8.06E-141 T 26-04-2017 A4V04_RS08740 3c46e76a3ab677e153edf41e84d2dbe1 487 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 459 476 - T 26-04-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS08740 3c46e76a3ab677e153edf41e84d2dbe1 487 PRINTS PR00662 Glucose-6-phosphate isomerase signature 136 155 4.9E-35 T 26-04-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS08740 3c46e76a3ab677e153edf41e84d2dbe1 487 PRINTS PR00662 Glucose-6-phosphate isomerase signature 427 445 4.9E-35 T 26-04-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS08740 3c46e76a3ab677e153edf41e84d2dbe1 487 PRINTS PR00662 Glucose-6-phosphate isomerase signature 459 472 4.9E-35 T 26-04-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS08740 3c46e76a3ab677e153edf41e84d2dbe1 487 PRINTS PR00662 Glucose-6-phosphate isomerase signature 445 459 4.9E-35 T 26-04-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS08740 3c46e76a3ab677e153edf41e84d2dbe1 487 PRINTS PR00662 Glucose-6-phosphate isomerase signature 325 346 4.9E-35 T 26-04-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS08740 3c46e76a3ab677e153edf41e84d2dbe1 487 PRINTS PR00662 Glucose-6-phosphate isomerase signature 248 266 4.9E-35 T 26-04-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS05180 3477257188d2b6093ba4e6b0075d3e33 338 Pfam PF02618 YceG-like family 46 331 6.7E-79 T 26-04-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like A4V04_RS05180 3477257188d2b6093ba4e6b0075d3e33 338 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 39 336 2.9E-77 T 26-04-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like A4V04_RS05180 3477257188d2b6093ba4e6b0075d3e33 338 Gene3D G3DSA:3.30.160.60 304 335 6.2E-16 T 26-04-2017 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 A4V04_RS04550 42ff17e774558e4934ce537f107c44b4 110 Gene3D G3DSA:2.30.110.10 1 106 9.1E-23 T 26-04-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4V04_RS04550 42ff17e774558e4934ce537f107c44b4 110 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 10 106 4.4E-11 T 26-04-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related A4V04_RS04550 42ff17e774558e4934ce537f107c44b4 110 SUPERFAMILY SSF50475 1 106 6.41E-22 T 26-04-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4V04_RS07075 5370ef44b22444ba883241619542d994 280 Gene3D G3DSA:2.160.20.10 119 229 1.0E-6 T 26-04-2017 IPR012334 Pectin lyase fold A4V04_RS07075 5370ef44b22444ba883241619542d994 280 Pfam PF12541 Protein of unknown function (DUF3737) 6 270 3.4E-107 T 26-04-2017 IPR022208 Protein of unknown function DUF3737 A4V04_RS07075 5370ef44b22444ba883241619542d994 280 SUPERFAMILY SSF51126 87 230 1.36E-11 T 26-04-2017 IPR011050 Pectin lyase fold/virulence factor A4V04_RS08495 1c38767920dd0e9318d81d990c129983 201 Pfam PF13410 Glutathione S-transferase, C-terminal domain 117 181 1.7E-8 T 26-04-2017 A4V04_RS08495 1c38767920dd0e9318d81d990c129983 201 Gene3D G3DSA:1.20.1050.10 90 196 1.1E-18 T 26-04-2017 IPR010987 Glutathione S-transferase, C-terminal-like A4V04_RS08495 1c38767920dd0e9318d81d990c129983 201 Gene3D G3DSA:3.40.30.10 1 89 6.3E-33 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS08495 1c38767920dd0e9318d81d990c129983 201 SUPERFAMILY SSF52833 1 99 1.34E-25 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS08495 1c38767920dd0e9318d81d990c129983 201 SUPERFAMILY SSF47616 73 200 8.81E-26 T 26-04-2017 IPR010987 Glutathione S-transferase, C-terminal-like A4V04_RS08495 1c38767920dd0e9318d81d990c129983 201 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 77 3.3E-16 T 26-04-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 A4V04_RS00105 fd2bdb231ac2732015ae404ce2de9dc4 296 Pfam PF03466 LysR substrate binding domain 89 289 1.1E-19 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS00105 fd2bdb231ac2732015ae404ce2de9dc4 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.7E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS00105 fd2bdb231ac2732015ae404ce2de9dc4 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.7E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS00105 fd2bdb231ac2732015ae404ce2de9dc4 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.7E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS00105 fd2bdb231ac2732015ae404ce2de9dc4 296 SUPERFAMILY SSF53850 89 290 5.55E-20 T 26-04-2017 A4V04_RS00105 fd2bdb231ac2732015ae404ce2de9dc4 296 Gene3D G3DSA:3.40.190.10 81 206 2.6E-14 T 26-04-2017 A4V04_RS00105 fd2bdb231ac2732015ae404ce2de9dc4 296 Gene3D G3DSA:1.10.10.10 1 80 2.5E-27 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS00105 fd2bdb231ac2732015ae404ce2de9dc4 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.6E-20 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS00105 fd2bdb231ac2732015ae404ce2de9dc4 296 SUPERFAMILY SSF46785 1 110 2.45E-23 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09735 75aad5de3ac66cf88ae1e780567dd244 326 Pfam PF00892 EamA-like transporter family 3 109 4.5E-8 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS09735 75aad5de3ac66cf88ae1e780567dd244 326 SUPERFAMILY SSF103481 208 303 8.37E-5 T 26-04-2017 A4V04_RS10625 6fdbb1a58c81111e2bfd858c47fe937b 256 Pfam PF00005 ABC transporter 25 174 5.3E-27 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS10625 6fdbb1a58c81111e2bfd858c47fe937b 256 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS10625 6fdbb1a58c81111e2bfd858c47fe937b 256 Gene3D G3DSA:3.40.50.300 3 251 1.3E-60 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10625 6fdbb1a58c81111e2bfd858c47fe937b 256 SUPERFAMILY SSF52540 9 247 2.23E-56 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10625 6fdbb1a58c81111e2bfd858c47fe937b 256 SMART SM00382 34 223 5.5E-11 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS02620 0db13e1457e92dc2cb1e890fff3bbe42 324 SUPERFAMILY SSF53850 27 323 1.35E-73 T 26-04-2017 A4V04_RS02620 0db13e1457e92dc2cb1e890fff3bbe42 324 Gene3D G3DSA:3.40.190.10 119 253 5.9E-27 T 26-04-2017 A4V04_RS02620 0db13e1457e92dc2cb1e890fff3bbe42 324 Pfam PF16868 NMT1-like family 32 321 7.1E-86 T 26-04-2017 IPR011852 TRAP transporter solute receptor, TAXI family A4V04_RS02620 0db13e1457e92dc2cb1e890fff3bbe42 324 Gene3D G3DSA:3.40.190.10 27 110 8.4E-59 T 26-04-2017 A4V04_RS02620 0db13e1457e92dc2cb1e890fff3bbe42 324 Gene3D G3DSA:3.40.190.10 254 322 8.4E-59 T 26-04-2017 A4V04_RS02620 0db13e1457e92dc2cb1e890fff3bbe42 324 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 5 321 7.8E-96 T 26-04-2017 IPR011852 TRAP transporter solute receptor, TAXI family A4V04_RS05375 ce78a8c1540fca5b31feb6feccbfb630 603 SUPERFAMILY SSF53850 56 277 2.03E-9 T 26-04-2017 A4V04_RS05375 ce78a8c1540fca5b31feb6feccbfb630 603 SMART SM00388 380 450 5.5E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05375 ce78a8c1540fca5b31feb6feccbfb630 603 SMART SM00387 491 600 1.2E-9 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05375 ce78a8c1540fca5b31feb6feccbfb630 603 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 49 305 4.6E-23 T 26-04-2017 A4V04_RS05375 ce78a8c1540fca5b31feb6feccbfb630 603 Gene3D G3DSA:1.10.287.130 382 435 5.7E-6 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05375 ce78a8c1540fca5b31feb6feccbfb630 603 SUPERFAMILY SSF47384 377 448 5.1E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05375 ce78a8c1540fca5b31feb6feccbfb630 603 SUPERFAMILY SSF55874 452 598 1.36E-19 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05375 ce78a8c1540fca5b31feb6feccbfb630 603 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 492 596 3.9E-8 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05375 ce78a8c1540fca5b31feb6feccbfb630 603 Gene3D G3DSA:3.40.190.10 128 232 6.9E-8 T 26-04-2017 A4V04_RS05375 ce78a8c1540fca5b31feb6feccbfb630 603 Pfam PF00512 His Kinase A (phospho-acceptor) domain 383 449 8.8E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05375 ce78a8c1540fca5b31feb6feccbfb630 603 Gene3D G3DSA:3.30.565.10 436 601 1.5E-21 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS00875 e9e7f56e97dba6e09bef6d104924d2ee 148 SUPERFAMILY SSF89095 1 146 5.75E-44 T 26-04-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 A4V04_RS00875 e9e7f56e97dba6e09bef6d104924d2ee 148 Pfam PF09424 Yqey-like protein 4 146 1.7E-51 T 26-04-2017 IPR019004 Uncharacterised domain YOR215C, mitochondrial A4V04_RS00875 e9e7f56e97dba6e09bef6d104924d2ee 148 Gene3D G3DSA:1.10.10.410 91 147 6.7E-21 T 26-04-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A4V04_RS00875 e9e7f56e97dba6e09bef6d104924d2ee 148 Gene3D G3DSA:1.10.1510.10 1 90 1.2E-32 T 26-04-2017 A4V04_RS11355 ee83273085dbb70667a52b0a75d5c0f0 135 Pfam PF01196 Ribosomal protein L17 20 116 1.3E-35 T 26-04-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11355 ee83273085dbb70667a52b0a75d5c0f0 135 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 26-04-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11355 ee83273085dbb70667a52b0a75d5c0f0 135 SUPERFAMILY SSF64263 1 117 2.22E-49 T 26-04-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11355 ee83273085dbb70667a52b0a75d5c0f0 135 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 116 1.8E-46 T 26-04-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11355 ee83273085dbb70667a52b0a75d5c0f0 135 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.945 T 26-04-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11355 ee83273085dbb70667a52b0a75d5c0f0 135 Gene3D G3DSA:3.90.1030.10 1 117 1.1E-49 T 26-04-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS10900 2364b9edf0bc94e2c6f8f66c2ac72d75 522 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 504 1.5E-173 T 26-04-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 A4V04_RS06360 627a97f7d56494563d2665e3f48bd0d8 88 Gene3D G3DSA:2.10.260.10 1 87 3.3E-15 T 26-04-2017 A4V04_RS06360 627a97f7d56494563d2665e3f48bd0d8 88 SMART SM00966 7 52 0.0026 T 26-04-2017 IPR007159 SpoVT-AbrB domain GO:0003677 A4V04_RS06360 627a97f7d56494563d2665e3f48bd0d8 88 SUPERFAMILY SSF89447 3 62 2.96E-9 T 26-04-2017 A4V04_RS08825 a39f2cb611b80773a32111df8a639cdc 399 Pfam PF13609 Gram-negative porin 9 370 5.5E-33 T 26-04-2017 A4V04_RS08825 a39f2cb611b80773a32111df8a639cdc 399 SUPERFAMILY SSF56935 20 399 9.16E-45 T 26-04-2017 A4V04_RS08825 a39f2cb611b80773a32111df8a639cdc 399 Gene3D G3DSA:2.40.160.10 21 399 1.7E-55 T 26-04-2017 IPR023614 Porin domain A4V04_RS10140 3ddba99b716ef39cc0c5d9d659469834 111 SUPERFAMILY SSF48695 7 105 1.44E-14 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS10140 3ddba99b716ef39cc0c5d9d659469834 111 Gene3D G3DSA:3.90.10.10 5 105 3.9E-12 T 26-04-2017 A4V04_RS10140 3ddba99b716ef39cc0c5d9d659469834 111 Pfam PF14537 Cytochrome c3 30 105 1.0E-17 T 26-04-2017 A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 SUPERFAMILY SSF46548 112 262 2.2E-16 T 26-04-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 SUPERFAMILY SSF140490 57 148 3.79E-20 T 26-04-2017 A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 160 236 6.9E-18 T 26-04-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 Gene3D G3DSA:3.40.50.720 508 583 1.7E-24 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 Gene3D G3DSA:3.40.50.720 257 345 1.7E-24 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 Gene3D G3DSA:3.50.50.60 346 504 5.9E-32 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 Gene3D G3DSA:1.10.1060.10 162 256 3.7E-23 T 26-04-2017 A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 Gene3D G3DSA:1.10.1060.10 603 645 1.1E-9 T 26-04-2017 A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 62 145 6.5E-18 T 26-04-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 PRINTS PR00419 Adrenodoxin reductase family signature 394 408 9.4E-13 T 26-04-2017 A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 PRINTS PR00419 Adrenodoxin reductase family signature 255 277 9.4E-13 T 26-04-2017 A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 PRINTS PR00419 Adrenodoxin reductase family signature 278 291 9.4E-13 T 26-04-2017 A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 255 559 1.7E-29 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 SMART SM00928 60 105 2.6E-7 T 26-04-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 SUPERFAMILY SSF51971 254 504 6.47E-47 T 26-04-2017 A4V04_RS04870 d0deedfc778da53bcd02658941d7d0bc 661 SUPERFAMILY SSF46548 604 645 4.84E-6 T 26-04-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 A4V04_RS08250 259c3cffb9c7f3301aa3f7264fa30861 315 Pfam PF01148 Cytidylyltransferase family 50 312 1.8E-34 T 26-04-2017 A4V04_RS01625 96314b6bd6fc7030575cdcb64e697c3b 348 Gene3D G3DSA:3.40.640.10 4 257 1.3E-48 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS01625 96314b6bd6fc7030575cdcb64e697c3b 348 Gene3D G3DSA:3.90.1150.10 259 347 1.3E-25 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS01625 96314b6bd6fc7030575cdcb64e697c3b 348 Pfam PF01212 Beta-eliminating lyase 58 300 1.4E-27 T 26-04-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 A4V04_RS01625 96314b6bd6fc7030575cdcb64e697c3b 348 SUPERFAMILY SSF53383 2 347 3.81E-63 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS04270 8fedaa75cbd33c999c1bbe2f4e044af9 468 SUPERFAMILY SSF48557 2 462 9.13E-135 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS04270 8fedaa75cbd33c999c1bbe2f4e044af9 468 Pfam PF10415 Fumarase C C-terminus 409 462 4.0E-14 T 26-04-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS04270 8fedaa75cbd33c999c1bbe2f4e044af9 468 PRINTS PR00149 Fumarate lyase superfamily signature 318 334 2.2E-28 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS04270 8fedaa75cbd33c999c1bbe2f4e044af9 468 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 2.2E-28 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS04270 8fedaa75cbd33c999c1bbe2f4e044af9 468 PRINTS PR00149 Fumarate lyase superfamily signature 272 299 2.2E-28 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS04270 8fedaa75cbd33c999c1bbe2f4e044af9 468 PRINTS PR00149 Fumarate lyase superfamily signature 181 199 2.2E-28 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS04270 8fedaa75cbd33c999c1bbe2f4e044af9 468 Gene3D G3DSA:1.10.40.30 409 466 2.8E-13 T 26-04-2017 A4V04_RS04270 8fedaa75cbd33c999c1bbe2f4e044af9 468 PRINTS PR00145 Argininosuccinate lyase family signature 318 334 8.3E-7 T 26-04-2017 A4V04_RS04270 8fedaa75cbd33c999c1bbe2f4e044af9 468 PRINTS PR00145 Argininosuccinate lyase family signature 135 157 8.3E-7 T 26-04-2017 A4V04_RS04270 8fedaa75cbd33c999c1bbe2f4e044af9 468 PRINTS PR00145 Argininosuccinate lyase family signature 176 196 8.3E-7 T 26-04-2017 A4V04_RS04270 8fedaa75cbd33c999c1bbe2f4e044af9 468 Pfam PF00206 Lyase 10 343 2.1E-92 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS04270 8fedaa75cbd33c999c1bbe2f4e044af9 468 ProSitePatterns PS00163 Fumarate lyases signature. 318 327 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS04270 8fedaa75cbd33c999c1bbe2f4e044af9 468 Gene3D G3DSA:1.20.200.10 141 403 8.3E-88 T 26-04-2017 A4V04_RS04270 8fedaa75cbd33c999c1bbe2f4e044af9 468 Gene3D G3DSA:1.10.275.10 2 140 7.4E-48 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS07920 e944a317506c8250ff1c32ceeeacbbd1 264 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 24 135 2.8E-30 T 26-04-2017 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 A4V04_RS07920 e944a317506c8250ff1c32ceeeacbbd1 264 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 145 229 1.7E-19 T 26-04-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 A4V04_RS07920 e944a317506c8250ff1c32ceeeacbbd1 264 Gene3D G3DSA:3.10.50.40 119 234 2.3E-34 T 26-04-2017 A4V04_RS07920 e944a317506c8250ff1c32ceeeacbbd1 264 Gene3D G3DSA:1.10.287.460 21 118 3.7E-31 T 26-04-2017 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 A4V04_RS07920 e944a317506c8250ff1c32ceeeacbbd1 264 SUPERFAMILY SSF54534 29 232 2.75E-51 T 26-04-2017 A4V04_RS10075 8bcf51b3f7cc7eda744a72eed3af33a6 443 Gene3D G3DSA:2.40.170.20 2 443 4.6E-66 T 26-04-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A4V04_RS10075 8bcf51b3f7cc7eda744a72eed3af33a6 443 Pfam PF00593 TonB dependent receptor 181 437 2.3E-25 T 26-04-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A4V04_RS10075 8bcf51b3f7cc7eda744a72eed3af33a6 443 SUPERFAMILY SSF56935 2 443 3.4E-57 T 26-04-2017 A4V04_RS06685 0add245053ed77e4ddb3ab9c27e02e9d 464 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 463 37.669 T 26-04-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A4V04_RS06685 0add245053ed77e4ddb3ab9c27e02e9d 464 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 463 5.3E-167 T 26-04-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A4V04_RS06685 0add245053ed77e4ddb3ab9c27e02e9d 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 4.8E-29 T 26-04-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4V04_RS06685 0add245053ed77e4ddb3ab9c27e02e9d 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 192 210 4.8E-29 T 26-04-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4V04_RS06685 0add245053ed77e4ddb3ab9c27e02e9d 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 4.8E-29 T 26-04-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4V04_RS06685 0add245053ed77e4ddb3ab9c27e02e9d 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 223 244 4.8E-29 T 26-04-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4V04_RS06685 0add245053ed77e4ddb3ab9c27e02e9d 464 Gene3D G3DSA:3.40.50.620 20 314 4.0E-104 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS06685 0add245053ed77e4ddb3ab9c27e02e9d 464 SMART SM00840 351 406 2.4E-24 T 26-04-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A4V04_RS06685 0add245053ed77e4ddb3ab9c27e02e9d 464 SUPERFAMILY SSF52374 3 321 5.9E-94 T 26-04-2017 A4V04_RS06685 0add245053ed77e4ddb3ab9c27e02e9d 464 Gene3D G3DSA:1.20.120.640 318 396 1.7E-21 T 26-04-2017 A4V04_RS06685 0add245053ed77e4ddb3ab9c27e02e9d 464 Pfam PF09190 DALR domain 351 406 1.2E-19 T 26-04-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A4V04_RS06685 0add245053ed77e4ddb3ab9c27e02e9d 464 SUPERFAMILY SSF47323 325 462 3.14E-34 T 26-04-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS06685 0add245053ed77e4ddb3ab9c27e02e9d 464 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 321 3.4E-125 T 26-04-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A4V04_RS06685 0add245053ed77e4ddb3ab9c27e02e9d 464 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 368 377 - T 26-04-2017 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 A4V04_RS10580 54ea7782fb966454ca64c2d42ff16bea 547 SUPERFAMILY SSF48557 3 545 1.1E-125 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS10580 54ea7782fb966454ca64c2d42ff16bea 547 Gene3D G3DSA:1.20.200.10 225 544 5.6E-67 T 26-04-2017 A4V04_RS10580 54ea7782fb966454ca64c2d42ff16bea 547 Gene3D G3DSA:1.10.275.10 20 222 4.8E-50 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS10580 54ea7782fb966454ca64c2d42ff16bea 547 Pfam PF00221 Aromatic amino acid lyase 28 519 1.3E-122 T 26-04-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 A4V04_RS02725 37597d594913978d9f59964788c618b0 123 SUPERFAMILY SSF89919 8 113 2.09E-27 T 26-04-2017 IPR023799 Ribosome-binding factor A domain A4V04_RS02725 37597d594913978d9f59964788c618b0 123 Gene3D G3DSA:3.30.300.20 7 118 1.1E-32 T 26-04-2017 IPR015946 K homology domain-like, alpha/beta A4V04_RS02725 37597d594913978d9f59964788c618b0 123 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 8 112 1.7E-24 T 26-04-2017 IPR000238 Ribosome-binding factor A GO:0006364 A4V04_RS02725 37597d594913978d9f59964788c618b0 123 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 5 117 18.759 T 26-04-2017 IPR000238 Ribosome-binding factor A GO:0006364 A4V04_RS02725 37597d594913978d9f59964788c618b0 123 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 13 97 1.0E-22 T 26-04-2017 IPR000238 Ribosome-binding factor A GO:0006364 A4V04_RS02725 37597d594913978d9f59964788c618b0 123 Pfam PF02033 Ribosome-binding factor A 9 110 9.0E-26 T 26-04-2017 IPR000238 Ribosome-binding factor A GO:0006364 A4V04_RS09485 c28185240adea1cb3857ea99de86ccac 505 SUPERFAMILY SSF52540 273 481 2.45E-34 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09485 c28185240adea1cb3857ea99de86ccac 505 ProSitePatterns PS00211 ABC transporters family signature. 394 408 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS09485 c28185240adea1cb3857ea99de86ccac 505 Pfam PF00005 ABC transporter 22 165 1.3E-32 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS09485 c28185240adea1cb3857ea99de86ccac 505 Pfam PF00005 ABC transporter 274 421 2.8E-11 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS09485 c28185240adea1cb3857ea99de86ccac 505 SUPERFAMILY SSF52540 3 226 1.66E-62 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09485 c28185240adea1cb3857ea99de86ccac 505 SMART SM00382 29 212 1.3E-10 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS09485 c28185240adea1cb3857ea99de86ccac 505 Gene3D G3DSA:3.40.50.300 2 229 3.0E-66 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09485 c28185240adea1cb3857ea99de86ccac 505 Gene3D G3DSA:3.40.50.300 273 480 1.6E-35 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07965 f2383ffd3ad65afc3320943599f571fe 295 Pfam PF03916 Polysulphide reductase, NrfD 12 289 7.2E-19 T 26-04-2017 IPR005614 NrfD family A4V04_RS03885 a6caf6212e328bf76c779b78df0c61b2 377 SUPERFAMILY SSF102114 11 323 1.44E-42 T 26-04-2017 A4V04_RS03885 a6caf6212e328bf76c779b78df0c61b2 377 PIRSF PIRSF004762 3 368 1.4E-57 T 26-04-2017 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 A4V04_RS03885 a6caf6212e328bf76c779b78df0c61b2 377 Pfam PF04055 Radical SAM superfamily 56 226 6.3E-9 T 26-04-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 A4V04_RS03885 a6caf6212e328bf76c779b78df0c61b2 377 Gene3D G3DSA:3.20.20.70 12 334 2.7E-64 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS03885 a6caf6212e328bf76c779b78df0c61b2 377 TIGRFAM TIGR03956 rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE 5 355 3.5E-84 T 26-04-2017 IPR024021 [FeFe]-hydrogenase maturation HydE, radical SAM A4V04_RS03885 a6caf6212e328bf76c779b78df0c61b2 377 SMART SM00729 51 268 5.9E-5 T 26-04-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4V04_RS02915 80b169b0fcd2f24b7d69f77f91a29c8a 299 Hamap MF_00367 GTPase Era [era]. 8 298 34.833 T 26-04-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 A4V04_RS02915 80b169b0fcd2f24b7d69f77f91a29c8a 299 Gene3D G3DSA:3.40.50.300 9 195 3.6E-44 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02915 80b169b0fcd2f24b7d69f77f91a29c8a 299 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 81 99 6.2E-7 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS02915 80b169b0fcd2f24b7d69f77f91a29c8a 299 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 13 33 6.2E-7 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS02915 80b169b0fcd2f24b7d69f77f91a29c8a 299 Gene3D G3DSA:3.30.300.20 196 295 1.1E-37 T 26-04-2017 IPR015946 K homology domain-like, alpha/beta A4V04_RS02915 80b169b0fcd2f24b7d69f77f91a29c8a 299 Pfam PF07650 KH domain 211 286 7.2E-17 T 26-04-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS02915 80b169b0fcd2f24b7d69f77f91a29c8a 299 Pfam PF01926 50S ribosome-binding GTPase 13 127 3.0E-27 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS02915 80b169b0fcd2f24b7d69f77f91a29c8a 299 SUPERFAMILY SSF54814 184 299 2.98E-39 T 26-04-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 A4V04_RS02915 80b169b0fcd2f24b7d69f77f91a29c8a 299 SUPERFAMILY SSF52540 13 205 2.57E-45 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02915 80b169b0fcd2f24b7d69f77f91a29c8a 299 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 172 1.3E-25 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS02915 80b169b0fcd2f24b7d69f77f91a29c8a 299 TIGRFAM TIGR00436 era: GTP-binding protein Era 11 281 3.9E-82 T 26-04-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 A4V04_RS00995 297baae3bc9556160efc4e2d5c0515ae 545 Pfam PF05598 Transposase domain (DUF772) 51 119 2.3E-7 T 26-04-2017 IPR008490 Transposase InsH, N-terminal A4V04_RS00995 297baae3bc9556160efc4e2d5c0515ae 545 Pfam PF13751 Transposase DDE domain 383 487 1.7E-21 T 26-04-2017 IPR025668 Transposase DDE domain A4V04_RS00350 297baae3bc9556160efc4e2d5c0515ae 545 Pfam PF05598 Transposase domain (DUF772) 51 119 2.3E-7 T 26-04-2017 IPR008490 Transposase InsH, N-terminal A4V04_RS00350 297baae3bc9556160efc4e2d5c0515ae 545 Pfam PF13751 Transposase DDE domain 383 487 1.7E-21 T 26-04-2017 IPR025668 Transposase DDE domain A4V04_RS00915 d9c1a6d7c6e4354c285cee9cc7ab8009 250 SUPERFAMILY SSF69618 1 234 9.29E-31 T 26-04-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00915 d9c1a6d7c6e4354c285cee9cc7ab8009 250 Pfam PF02602 Uroporphyrinogen-III synthase HemD 31 231 1.3E-23 T 26-04-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00915 d9c1a6d7c6e4354c285cee9cc7ab8009 250 Gene3D G3DSA:3.40.50.10090 135 227 1.9E-8 T 26-04-2017 A4V04_RS00915 d9c1a6d7c6e4354c285cee9cc7ab8009 250 Gene3D G3DSA:3.40.50.10090 8 106 8.7E-7 T 26-04-2017 A4V04_RS01500 266935df5446001fac384072429ad8c4 429 PIRSF PIRSF000505 1 429 1.9E-138 T 26-04-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4V04_RS01500 266935df5446001fac384072429ad8c4 429 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 11 429 31.512 T 26-04-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4V04_RS01500 266935df5446001fac384072429ad8c4 429 Gene3D G3DSA:3.65.10.10 239 425 1.4E-61 T 26-04-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 A4V04_RS01500 266935df5446001fac384072429ad8c4 429 Gene3D G3DSA:3.65.10.10 23 238 4.3E-63 T 26-04-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 A4V04_RS01500 266935df5446001fac384072429ad8c4 429 ProSitePatterns PS00104 EPSP synthase signature 1. 88 102 - T 26-04-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4V04_RS01500 266935df5446001fac384072429ad8c4 429 SUPERFAMILY SSF55205 5 426 1.59E-118 T 26-04-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A4V04_RS01500 266935df5446001fac384072429ad8c4 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 423 4.8E-124 T 26-04-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 A4V04_RS01500 266935df5446001fac384072429ad8c4 429 ProSitePatterns PS00885 EPSP synthase signature 2. 341 359 - T 26-04-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4V04_RS01500 266935df5446001fac384072429ad8c4 429 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 15 428 1.4E-127 T 26-04-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4V04_RS09320 fc7bf81bc5f7e5df9bca3e1c57cd4381 266 SUPERFAMILY SSF55347 123 226 1.11E-14 T 26-04-2017 A4V04_RS09320 fc7bf81bc5f7e5df9bca3e1c57cd4381 266 Gene3D G3DSA:3.30.360.10 128 235 2.2E-22 T 26-04-2017 A4V04_RS09320 fc7bf81bc5f7e5df9bca3e1c57cd4381 266 Pfam PF01958 Domain of unknown function DUF108 167 253 2.9E-20 T 26-04-2017 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 A4V04_RS09320 fc7bf81bc5f7e5df9bca3e1c57cd4381 266 Gene3D G3DSA:3.40.50.720 4 127 4.5E-9 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS09320 fc7bf81bc5f7e5df9bca3e1c57cd4381 266 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 8 119 2.2E-10 T 26-04-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A4V04_RS09320 fc7bf81bc5f7e5df9bca3e1c57cd4381 266 PIRSF PIRSF005227 1 265 8.1E-53 T 26-04-2017 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 A4V04_RS09320 fc7bf81bc5f7e5df9bca3e1c57cd4381 266 SUPERFAMILY SSF51735 2 148 9.61E-18 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03230 68b362e1ee87e29d165b0642f41dcfe7 207 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 8 201 3.8E-51 T 26-04-2017 IPR006070 YrdC-like domain GO:0003725 A4V04_RS03230 68b362e1ee87e29d165b0642f41dcfe7 207 SUPERFAMILY SSF55821 5 202 2.47E-53 T 26-04-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain A4V04_RS03230 68b362e1ee87e29d165b0642f41dcfe7 207 Pfam PF01300 Telomere recombination 23 198 1.6E-41 T 26-04-2017 IPR006070 YrdC-like domain GO:0003725 A4V04_RS03230 68b362e1ee87e29d165b0642f41dcfe7 207 Gene3D G3DSA:3.90.870.10 4 204 1.1E-55 T 26-04-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain A4V04_RS12745 d3c364b9eaeb41d97dd7e7f059a28d8e 1558 SUPERFAMILY SSF69336 1270 1547 2.88E-90 T 26-04-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A4V04_RS12745 d3c364b9eaeb41d97dd7e7f059a28d8e 1558 Gene3D G3DSA:2.160.20.60 1275 1548 8.3E-99 T 26-04-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A4V04_RS12745 d3c364b9eaeb41d97dd7e7f059a28d8e 1558 Pfam PF00310 Glutamine amidotransferases class-II 26 449 3.0E-183 T 26-04-2017 IPR017932 Glutamine amidotransferase type 2 domain A4V04_RS12745 d3c364b9eaeb41d97dd7e7f059a28d8e 1558 SUPERFAMILY SSF56235 26 451 2.01E-152 T 26-04-2017 IPR029055 Nucleophile aminohydrolases, N-terminal A4V04_RS12745 d3c364b9eaeb41d97dd7e7f059a28d8e 1558 SUPERFAMILY SSF51395 961 1256 7.33E-258 T 26-04-2017 A4V04_RS12745 d3c364b9eaeb41d97dd7e7f059a28d8e 1558 SUPERFAMILY SSF51395 468 931 7.33E-258 T 26-04-2017 A4V04_RS12745 d3c364b9eaeb41d97dd7e7f059a28d8e 1558 Pfam PF01493 GXGXG motif 1300 1486 6.6E-77 T 26-04-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A4V04_RS12745 d3c364b9eaeb41d97dd7e7f059a28d8e 1558 Pfam PF01645 Conserved region in glutamate synthase 822 1221 2.7E-156 T 26-04-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 A4V04_RS12745 d3c364b9eaeb41d97dd7e7f059a28d8e 1558 Gene3D G3DSA:3.60.20.10 26 460 8.3E-183 T 26-04-2017 IPR029055 Nucleophile aminohydrolases, N-terminal A4V04_RS12745 d3c364b9eaeb41d97dd7e7f059a28d8e 1558 Pfam PF04898 Glutamate synthase central domain 476 762 6.3E-107 T 26-04-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 A4V04_RS12745 d3c364b9eaeb41d97dd7e7f059a28d8e 1558 Gene3D G3DSA:3.20.20.70 854 1260 1.1E-178 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS12745 d3c364b9eaeb41d97dd7e7f059a28d8e 1558 Gene3D G3DSA:3.20.20.70 468 804 2.7E-103 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS03160 34cae87f3a6e5a42ee679b89919610f3 110 Pfam PF00037 4Fe-4S binding domain 34 55 4.2E-7 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS03160 34cae87f3a6e5a42ee679b89919610f3 110 Gene3D G3DSA:3.30.70.20 4 99 1.6E-21 T 26-04-2017 A4V04_RS03160 34cae87f3a6e5a42ee679b89919610f3 110 SUPERFAMILY SSF54862 3 103 6.05E-25 T 26-04-2017 A4V04_RS03160 34cae87f3a6e5a42ee679b89919610f3 110 Pfam PF11953 Domain of unknown function (DUF3470) 66 106 1.7E-16 T 26-04-2017 IPR022569 Ferredoxin, C-terminal A4V04_RS03160 34cae87f3a6e5a42ee679b89919610f3 110 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS03160 34cae87f3a6e5a42ee679b89919610f3 110 PRINTS PR00354 7Fe ferredoxin signature 9 19 9.6E-15 T 26-04-2017 IPR000813 7Fe ferredoxin GO:0009055 A4V04_RS03160 34cae87f3a6e5a42ee679b89919610f3 110 PRINTS PR00354 7Fe ferredoxin signature 35 52 9.6E-15 T 26-04-2017 IPR000813 7Fe ferredoxin GO:0009055 A4V04_RS03160 34cae87f3a6e5a42ee679b89919610f3 110 PRINTS PR00354 7Fe ferredoxin signature 19 29 9.6E-15 T 26-04-2017 IPR000813 7Fe ferredoxin GO:0009055 A4V04_RS07250 67da8a05c903fe517210bb147d9303cc 1232 SUPERFAMILY SSF52540 132 193 1.1E-20 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07250 67da8a05c903fe517210bb147d9303cc 1232 SUPERFAMILY SSF52540 6 101 1.1E-20 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07250 67da8a05c903fe517210bb147d9303cc 1232 SUPERFAMILY SSF52540 260 290 1.1E-20 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07250 67da8a05c903fe517210bb147d9303cc 1232 SUPERFAMILY SSF52540 1116 1185 1.1E-20 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07250 67da8a05c903fe517210bb147d9303cc 1232 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1108 1178 4.6E-13 T 26-04-2017 A4V04_RS07250 67da8a05c903fe517210bb147d9303cc 1232 Gene3D G3DSA:3.40.50.300 1114 1199 1.7E-7 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07250 67da8a05c903fe517210bb147d9303cc 1232 Gene3D G3DSA:3.40.50.300 1 167 6.0E-26 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07250 67da8a05c903fe517210bb147d9303cc 1232 Pfam PF13476 AAA domain 5 213 1.7E-28 T 26-04-2017 A4V04_RS11235 098791398b6c3b18c9231e3e9d6d3cef 99 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 7 97 21.054 T 26-04-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A4V04_RS11235 098791398b6c3b18c9231e3e9d6d3cef 99 Gene3D G3DSA:3.30.70.330 6 98 4.1E-32 T 26-04-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 A4V04_RS11235 098791398b6c3b18c9231e3e9d6d3cef 99 SUPERFAMILY SSF54189 6 92 1.37E-28 T 26-04-2017 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11235 098791398b6c3b18c9231e3e9d6d3cef 99 Pfam PF00276 Ribosomal protein L23 8 94 5.5E-28 T 26-04-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A4V04_RS13225 57dc1e0e929748ea9f0f475a7d8d1c81 131 Pfam PF01592 NifU-like N terminal domain 2 126 6.1E-55 T 26-04-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 A4V04_RS13225 57dc1e0e929748ea9f0f475a7d8d1c81 131 Gene3D G3DSA:3.90.1010.10 2 126 2.0E-55 T 26-04-2017 A4V04_RS13225 57dc1e0e929748ea9f0f475a7d8d1c81 131 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 126 4.4E-66 T 26-04-2017 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 A4V04_RS13225 57dc1e0e929748ea9f0f475a7d8d1c81 131 SUPERFAMILY SSF82649 1 125 3.92E-49 T 26-04-2017 A4V04_RS08120 96ceaa11068758b5747b2924e0ddda44 188 Gene3D G3DSA:2.30.22.10 132 188 3.7E-21 T 26-04-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A4V04_RS08120 96ceaa11068758b5747b2924e0ddda44 188 SUPERFAMILY SSF58014 42 132 1.57E-24 T 26-04-2017 A4V04_RS08120 96ceaa11068758b5747b2924e0ddda44 188 Gene3D G3DSA:3.90.20.20 42 130 1.2E-27 T 26-04-2017 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 A4V04_RS08120 96ceaa11068758b5747b2924e0ddda44 188 Pfam PF01025 GrpE 31 188 3.1E-47 T 26-04-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4V04_RS08120 96ceaa11068758b5747b2924e0ddda44 188 Hamap MF_01151 Protein GrpE [grpE]. 2 188 18.87 T 26-04-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4V04_RS08120 96ceaa11068758b5747b2924e0ddda44 188 SUPERFAMILY SSF51064 134 188 6.28E-16 T 26-04-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A4V04_RS08120 96ceaa11068758b5747b2924e0ddda44 188 PRINTS PR00773 GrpE protein signature 60 76 1.8E-22 T 26-04-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4V04_RS08120 96ceaa11068758b5747b2924e0ddda44 188 PRINTS PR00773 GrpE protein signature 140 155 1.8E-22 T 26-04-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4V04_RS08120 96ceaa11068758b5747b2924e0ddda44 188 PRINTS PR00773 GrpE protein signature 88 103 1.8E-22 T 26-04-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4V04_RS08120 96ceaa11068758b5747b2924e0ddda44 188 PRINTS PR00773 GrpE protein signature 167 186 1.8E-22 T 26-04-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4V04_RS04700 c45daf06bd27005867f8537cda5ce079 345 Gene3D G3DSA:3.40.640.10 1 253 4.2E-58 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS04700 c45daf06bd27005867f8537cda5ce079 345 Gene3D G3DSA:3.90.1150.10 256 344 3.4E-31 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS04700 c45daf06bd27005867f8537cda5ce079 345 SUPERFAMILY SSF53383 1 344 1.46E-72 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS04700 c45daf06bd27005867f8537cda5ce079 345 Pfam PF01212 Beta-eliminating lyase 15 258 6.1E-27 T 26-04-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 A4V04_RS06795 ee04fcf887bcba5e9b765b26d2b3ca01 247 Gene3D G3DSA:1.20.950.20 17 210 3.3E-22 T 26-04-2017 A4V04_RS06795 ee04fcf887bcba5e9b765b26d2b3ca01 247 SUPERFAMILY SSF81342 16 232 5.18E-34 T 26-04-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A4V04_RS06795 ee04fcf887bcba5e9b765b26d2b3ca01 247 TIGRFAM TIGR02125 CytB-hydogenase: Ni/Fe-hydrogenase, b-type cytochrome subunit 19 232 8.6E-53 T 26-04-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 A4V04_RS06795 ee04fcf887bcba5e9b765b26d2b3ca01 247 Pfam PF01292 Prokaryotic cytochrome b561 21 226 1.4E-25 T 26-04-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 A4V04_RS06795 ee04fcf887bcba5e9b765b26d2b3ca01 247 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 140 159 3.6E-31 T 26-04-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 A4V04_RS06795 ee04fcf887bcba5e9b765b26d2b3ca01 247 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 187 209 3.6E-31 T 26-04-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 A4V04_RS06795 ee04fcf887bcba5e9b765b26d2b3ca01 247 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 61 85 3.6E-31 T 26-04-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 A4V04_RS06795 ee04fcf887bcba5e9b765b26d2b3ca01 247 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 23 46 3.6E-31 T 26-04-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 A4V04_RS06795 ee04fcf887bcba5e9b765b26d2b3ca01 247 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 218 231 3.6E-31 T 26-04-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 A4V04_RS07260 e0aa2a0a3e735940b5a65414a3b031b9 398 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 242 329 1.4E-8 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS07260 e0aa2a0a3e735940b5a65414a3b031b9 398 Pfam PF12323 Helix-turn-helix domain 1 45 7.8E-12 T 26-04-2017 IPR021027 Transposase, putative, helix-turn-helix domain A4V04_RS07260 e0aa2a0a3e735940b5a65414a3b031b9 398 Pfam PF01385 Probable transposase 169 273 9.1E-24 T 26-04-2017 IPR001959 Probable transposase, IS891/IS1136/IS1341 A4V04_RS07260 e0aa2a0a3e735940b5a65414a3b031b9 398 Pfam PF07282 Putative transposase DNA-binding domain 302 370 1.3E-21 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS04280 571e422ede70fcf804a2dc447d576d04 161 SMART SM00422 28 96 5.9E-7 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS04280 571e422ede70fcf804a2dc447d576d04 161 Pfam PF13411 MerR HTH family regulatory protein 29 92 3.8E-16 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS04280 571e422ede70fcf804a2dc447d576d04 161 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 63 83 3.1E-6 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS04280 571e422ede70fcf804a2dc447d576d04 161 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 53 3.1E-6 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS04280 571e422ede70fcf804a2dc447d576d04 161 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 29 40 3.1E-6 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS04280 571e422ede70fcf804a2dc447d576d04 161 SUPERFAMILY SSF46955 28 94 1.03E-14 T 26-04-2017 IPR009061 Putative DNA-binding domain A4V04_RS04280 571e422ede70fcf804a2dc447d576d04 161 Gene3D G3DSA:1.10.1660.10 25 92 1.1E-16 T 26-04-2017 A4V04_RS02075 135544fceae099028b56d3dffd998aff 344 Pfam PF04607 Region found in RelA / SpoT proteins 71 180 1.1E-20 T 26-04-2017 IPR007685 RelA/SpoT GO:0015969 A4V04_RS02075 135544fceae099028b56d3dffd998aff 344 Gene3D G3DSA:3.30.460.10 31 171 5.2E-26 T 26-04-2017 A4V04_RS02075 135544fceae099028b56d3dffd998aff 344 SUPERFAMILY SSF81301 32 225 1.63E-31 T 26-04-2017 A4V04_RS02075 135544fceae099028b56d3dffd998aff 344 SMART SM00954 71 191 8.8E-21 T 26-04-2017 IPR007685 RelA/SpoT GO:0015969 A4V04_RS03640 288d7cd719efa2fb1e90d4c719c4cc0b 125 SUPERFAMILY SSF46785 53 109 5.96E-6 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS03640 288d7cd719efa2fb1e90d4c719c4cc0b 125 Gene3D G3DSA:1.10.10.10 59 97 1.2E-5 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS13180 7a341fbd1206f3e3a6808f63ac749c13 400 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 247 260 - T 26-04-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A4V04_RS13180 7a341fbd1206f3e3a6808f63ac749c13 400 Gene3D G3DSA:3.40.640.10 50 319 1.0E-109 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS13180 7a341fbd1206f3e3a6808f63ac749c13 400 Pfam PF00155 Aminotransferase class I and II 31 396 3.0E-87 T 26-04-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4V04_RS13180 7a341fbd1206f3e3a6808f63ac749c13 400 SUPERFAMILY SSF53383 3 400 8.72E-122 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS13180 7a341fbd1206f3e3a6808f63ac749c13 400 PRINTS PR00799 Aspartate aminotransferase signature 277 302 3.4E-38 T 26-04-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 A4V04_RS13180 7a341fbd1206f3e3a6808f63ac749c13 400 PRINTS PR00799 Aspartate aminotransferase signature 345 363 3.4E-38 T 26-04-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 A4V04_RS13180 7a341fbd1206f3e3a6808f63ac749c13 400 PRINTS PR00799 Aspartate aminotransferase signature 210 222 3.4E-38 T 26-04-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 A4V04_RS13180 7a341fbd1206f3e3a6808f63ac749c13 400 PRINTS PR00799 Aspartate aminotransferase signature 179 198 3.4E-38 T 26-04-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 A4V04_RS08965 9a58b6032bd6f589d54775eb1e2ba5f4 472 SUPERFAMILY SSF51905 26 288 2.57E-52 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08965 9a58b6032bd6f589d54775eb1e2ba5f4 472 SUPERFAMILY SSF51905 412 469 2.57E-52 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08965 9a58b6032bd6f589d54775eb1e2ba5f4 472 Gene3D G3DSA:3.90.700.10 289 399 7.5E-18 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08965 9a58b6032bd6f589d54775eb1e2ba5f4 472 Pfam PF00890 FAD binding domain 34 453 2.5E-63 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08965 9a58b6032bd6f589d54775eb1e2ba5f4 472 Gene3D G3DSA:3.50.50.60 27 270 2.3E-84 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08965 9a58b6032bd6f589d54775eb1e2ba5f4 472 Gene3D G3DSA:3.50.50.60 409 469 2.3E-84 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08965 9a58b6032bd6f589d54775eb1e2ba5f4 472 SUPERFAMILY SSF56425 288 413 1.76E-20 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08965 9a58b6032bd6f589d54775eb1e2ba5f4 472 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 34 464 1.1E-96 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS03625 265d92a2b7fe356d3a3b244607f02ac9 122 SUPERFAMILY SSF50104 1 118 9.33E-45 T 26-04-2017 IPR008991 Translation protein SH3-like domain A4V04_RS03625 265d92a2b7fe356d3a3b244607f02ac9 122 Pfam PF01245 Ribosomal protein L19 2 117 6.6E-46 T 26-04-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS03625 265d92a2b7fe356d3a3b244607f02ac9 122 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 117 4.9E-47 T 26-04-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS03625 265d92a2b7fe356d3a3b244607f02ac9 122 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 26-04-2017 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS03625 265d92a2b7fe356d3a3b244607f02ac9 122 PRINTS PR00061 Ribosomal protein L19 signature 92 117 4.0E-32 T 26-04-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS03625 265d92a2b7fe356d3a3b244607f02ac9 122 PRINTS PR00061 Ribosomal protein L19 signature 8 37 4.0E-32 T 26-04-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS03625 265d92a2b7fe356d3a3b244607f02ac9 122 PRINTS PR00061 Ribosomal protein L19 signature 38 67 4.0E-32 T 26-04-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS03625 265d92a2b7fe356d3a3b244607f02ac9 122 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 118 29.13 T 26-04-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS03625 265d92a2b7fe356d3a3b244607f02ac9 122 PIRSF PIRSF002191 1 122 4.2E-50 T 26-04-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS08860 731b350513b1dd883aff5d25b46a73c3 189 Gene3D G3DSA:2.40.50.140 169 189 6.4E-47 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS08860 731b350513b1dd883aff5d25b46a73c3 189 Gene3D G3DSA:2.40.50.140 1 122 6.4E-47 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS08860 731b350513b1dd883aff5d25b46a73c3 189 Hamap MF_00984 Single-stranded DNA-binding protein. 4 112 32.704 T 26-04-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A4V04_RS08860 731b350513b1dd883aff5d25b46a73c3 189 SUPERFAMILY SSF50249 3 189 7.93E-50 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS08860 731b350513b1dd883aff5d25b46a73c3 189 Pfam PF00436 Single-strand binding protein family 4 108 1.1E-32 T 26-04-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 A4V04_RS08860 731b350513b1dd883aff5d25b46a73c3 189 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 189 5.5E-45 T 26-04-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A4V04_RS01505 828ff485464695a349e488f22e771159 221 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 214 8.6E-72 T 26-04-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 A4V04_RS01505 828ff485464695a349e488f22e771159 221 Gene3D G3DSA:3.40.50.300 6 216 7.8E-69 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01505 828ff485464695a349e488f22e771159 221 Hamap MF_00238 Cytidylate kinase [cmk]. 6 220 31.767 T 26-04-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 A4V04_RS01505 828ff485464695a349e488f22e771159 221 Pfam PF02224 Cytidylate kinase 8 215 4.0E-72 T 26-04-2017 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 A4V04_RS01505 828ff485464695a349e488f22e771159 221 SUPERFAMILY SSF52540 6 216 3.77E-39 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07490 b04ee99344a1e23957298cf0e3360f73 541 SUPERFAMILY SSF81301 35 177 2.07E-37 T 26-04-2017 A4V04_RS07490 b04ee99344a1e23957298cf0e3360f73 541 SUPERFAMILY SSF81891 179 406 1.26E-38 T 26-04-2017 A4V04_RS07490 b04ee99344a1e23957298cf0e3360f73 541 Pfam PF12626 Polymerase A arginine-rich C-terminus 329 450 9.7E-31 T 26-04-2017 IPR025866 Polymerase A arginine-rich C-terminal domain A4V04_RS07490 b04ee99344a1e23957298cf0e3360f73 541 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 24 447 8.4E-138 T 26-04-2017 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 A4V04_RS07490 b04ee99344a1e23957298cf0e3360f73 541 Pfam PF01743 Poly A polymerase head domain 55 180 1.2E-32 T 26-04-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A4V04_RS07490 b04ee99344a1e23957298cf0e3360f73 541 Gene3D G3DSA:3.30.460.10 37 179 2.2E-46 T 26-04-2017 A4V04_RS07490 b04ee99344a1e23957298cf0e3360f73 541 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 207 258 1.8E-13 T 26-04-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A4V04_RS07490 b04ee99344a1e23957298cf0e3360f73 541 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 19 532 31.972 T 26-04-2017 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 A4V04_RS07490 b04ee99344a1e23957298cf0e3360f73 541 Gene3D G3DSA:1.10.3090.10 180 408 9.6E-41 T 26-04-2017 A4V04_RS00450 078753145eb3a3f731a8b1783236d322 209 Pfam PF11041 Protein of unknown function (DUF2612) 29 90 2.0E-8 T 26-04-2017 IPR021283 Protein of unknown function DUF2612 A4V04_RS00450 078753145eb3a3f731a8b1783236d322 209 Pfam PF11041 Protein of unknown function (DUF2612) 95 175 2.4E-15 T 26-04-2017 IPR021283 Protein of unknown function DUF2612 A4V04_RS05305 86832241933cc688ce223db3db0c9019 182 Pfam PF13420 Acetyltransferase (GNAT) domain 7 161 3.3E-12 T 26-04-2017 A4V04_RS05305 86832241933cc688ce223db3db0c9019 182 SUPERFAMILY SSF55729 7 168 1.13E-29 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS05305 86832241933cc688ce223db3db0c9019 182 Gene3D G3DSA:3.40.630.30 4 171 1.6E-32 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS09675 5280f53a2793273b8c8dcaa214c28f28 320 SUPERFAMILY SSF46785 6 114 2.22E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09675 5280f53a2793273b8c8dcaa214c28f28 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 2.1E-19 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09675 5280f53a2793273b8c8dcaa214c28f28 320 Pfam PF03466 LysR substrate binding domain 98 251 8.6E-14 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS09675 5280f53a2793273b8c8dcaa214c28f28 320 SUPERFAMILY SSF53850 98 300 1.99E-18 T 26-04-2017 A4V04_RS09675 5280f53a2793273b8c8dcaa214c28f28 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.1E-9 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09675 5280f53a2793273b8c8dcaa214c28f28 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.1E-9 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09675 5280f53a2793273b8c8dcaa214c28f28 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.1E-9 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09675 5280f53a2793273b8c8dcaa214c28f28 320 Gene3D G3DSA:3.40.190.10 98 220 5.1E-12 T 26-04-2017 A4V04_RS09675 5280f53a2793273b8c8dcaa214c28f28 320 Gene3D G3DSA:1.10.10.10 7 88 3.2E-23 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS06815 ab258c9bf30398cbe6e1a618f8397b0f 147 Gene3D G3DSA:3.40.30.10 29 107 1.9E-16 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS06815 ab258c9bf30398cbe6e1a618f8397b0f 147 PIRSF PIRSF038934 12 143 1.5E-26 T 26-04-2017 IPR010893 [NiFe]-hydrogenase maturation factor HyaE A4V04_RS06815 ab258c9bf30398cbe6e1a618f8397b0f 147 SUPERFAMILY SSF52833 14 134 1.23E-10 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS06815 ab258c9bf30398cbe6e1a618f8397b0f 147 Pfam PF07449 Hydrogenase-1 expression protein HyaE 17 121 1.2E-22 T 26-04-2017 IPR010893 [NiFe]-hydrogenase maturation factor HyaE A4V04_RS05275 55a1d9fd6cc3c96a4b41f8c1870da19b 315 Gene3D G3DSA:3.40.50.720 1 216 5.3E-44 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS05275 55a1d9fd6cc3c96a4b41f8c1870da19b 315 Gene3D G3DSA:3.90.25.10 217 311 3.2E-5 T 26-04-2017 A4V04_RS05275 55a1d9fd6cc3c96a4b41f8c1870da19b 315 SUPERFAMILY SSF51735 1 311 1.74E-56 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS05275 55a1d9fd6cc3c96a4b41f8c1870da19b 315 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 243 1.2E-27 T 26-04-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4V04_RS06110 17d2efc066c7e8b28c39ed1436b5cb79 408 Gene3D G3DSA:2.40.340.10 333 400 6.7E-20 T 26-04-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS06110 17d2efc066c7e8b28c39ed1436b5cb79 408 Gene3D G3DSA:3.40.980.10 165 332 1.2E-57 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS06110 17d2efc066c7e8b28c39ed1436b5cb79 408 Gene3D G3DSA:3.90.105.10 133 164 4.1E-16 T 26-04-2017 A4V04_RS06110 17d2efc066c7e8b28c39ed1436b5cb79 408 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 169 1.0E-33 T 26-04-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS06110 17d2efc066c7e8b28c39ed1436b5cb79 408 Gene3D G3DSA:2.170.190.11 51 132 2.4E-28 T 26-04-2017 A4V04_RS06110 17d2efc066c7e8b28c39ed1436b5cb79 408 SMART SM00852 182 319 3.5E-37 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS06110 17d2efc066c7e8b28c39ed1436b5cb79 408 SUPERFAMILY SSF53218 179 322 4.19E-40 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS06110 17d2efc066c7e8b28c39ed1436b5cb79 408 Pfam PF03454 MoeA C-terminal region (domain IV) 333 403 2.2E-13 T 26-04-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS06110 17d2efc066c7e8b28c39ed1436b5cb79 408 SUPERFAMILY SSF63867 330 405 2.88E-16 T 26-04-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS06110 17d2efc066c7e8b28c39ed1436b5cb79 408 SUPERFAMILY SSF63882 7 178 8.76E-50 T 26-04-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS06110 17d2efc066c7e8b28c39ed1436b5cb79 408 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 178 314 8.9E-33 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS06110 17d2efc066c7e8b28c39ed1436b5cb79 408 Pfam PF00994 Probable molybdopterin binding domain 184 317 7.9E-27 T 26-04-2017 IPR001453 MoaB/Mog domain A4V04_RS00020 6e16b68fb07d0f4058cbb0f7aff60bce 64 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 2 64 7.8E-31 T 26-04-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 A4V04_RS00020 6e16b68fb07d0f4058cbb0f7aff60bce 64 SUPERFAMILY SSF140319 1 62 3.01E-25 T 26-04-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 A4V04_RS00020 6e16b68fb07d0f4058cbb0f7aff60bce 64 Pfam PF04384 Iron-sulphur cluster assembly 1 64 2.2E-30 T 26-04-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 A4V04_RS00020 6e16b68fb07d0f4058cbb0f7aff60bce 64 Gene3D G3DSA:1.10.10.600 1 64 2.7E-31 T 26-04-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 A4V04_RS00020 6e16b68fb07d0f4058cbb0f7aff60bce 64 PIRSF PIRSF039003 1 64 2.2E-31 T 26-04-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 Pfam PF00549 CoA-ligase 156 267 1.0E-14 T 26-04-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 SUPERFAMILY SSF52210 128 292 5.76E-52 T 26-04-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 PRINTS PR01798 Succinyl-CoA synthase signature 245 262 1.0E-35 T 26-04-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 PRINTS PR01798 Succinyl-CoA synthase signature 213 226 1.0E-35 T 26-04-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 PRINTS PR01798 Succinyl-CoA synthase signature 182 200 1.0E-35 T 26-04-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 PRINTS PR01798 Succinyl-CoA synthase signature 85 102 1.0E-35 T 26-04-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 241 254 - T 26-04-2017 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 SMART SM00881 4 103 6.4E-29 T 26-04-2017 IPR003781 CoA-binding GO:0048037 A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 157 186 - T 26-04-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 Pfam PF02629 CoA binding domain 6 102 1.3E-23 T 26-04-2017 IPR003781 CoA-binding GO:0048037 A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 PIRSF PIRSF001553 1 296 2.5E-118 T 26-04-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 293 2.6E-130 T 26-04-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 Gene3D G3DSA:3.40.50.261 125 292 1.5E-70 T 26-04-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 SUPERFAMILY SSF51735 1 127 4.68E-36 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS12405 2941ffc2f42a880d5dad06543f38a4ba 297 Gene3D G3DSA:3.40.50.720 2 124 1.4E-48 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS09945 d480ac0b98304ee2d7871aaa98c3f82f 212 Gene3D G3DSA:3.40.30.10 68 203 1.2E-17 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS09945 d480ac0b98304ee2d7871aaa98c3f82f 212 SUPERFAMILY SSF52833 68 202 7.02E-17 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS07500 51e0aa31205a2e34c2eb80da329dc2b6 219 Gene3D G3DSA:1.10.8.60 148 212 1.8E-22 T 26-04-2017 A4V04_RS07500 51e0aa31205a2e34c2eb80da329dc2b6 219 Gene3D G3DSA:3.40.50.300 78 145 1.1E-10 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07500 51e0aa31205a2e34c2eb80da329dc2b6 219 Gene3D G3DSA:3.40.50.300 3 62 1.3E-11 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07500 51e0aa31205a2e34c2eb80da329dc2b6 219 Pfam PF00308 Bacterial dnaA protein 78 196 1.9E-13 T 26-04-2017 IPR013317 Chromosomal replication initiator protein DnaA A4V04_RS07500 51e0aa31205a2e34c2eb80da329dc2b6 219 SUPERFAMILY SSF52540 17 193 2.38E-19 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00990 f4f7d3707a8fba2164c2e5b8600f58a5 131 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 79 90 - T 26-04-2017 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 A4V04_RS00990 f4f7d3707a8fba2164c2e5b8600f58a5 131 Pfam PF01219 Prokaryotic diacylglycerol kinase 25 126 9.0E-34 T 26-04-2017 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 A4V04_RS00990 f4f7d3707a8fba2164c2e5b8600f58a5 131 Gene3D G3DSA:1.10.3830.10 13 130 2.0E-42 T 26-04-2017 A4V04_RS05910 c5b78076a623e674974f524674ede90d 249 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 1 12 - T 26-04-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A4V04_RS05910 c5b78076a623e674974f524674ede90d 249 SUPERFAMILY SSF52313 1 227 2.09E-90 T 26-04-2017 IPR023591 Ribosomal protein S2, flavodoxin-like domain A4V04_RS05910 c5b78076a623e674974f524674ede90d 249 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 1 220 37.386 T 26-04-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 A4V04_RS05910 c5b78076a623e674974f524674ede90d 249 PRINTS PR00395 Ribosomal protein S2 signature 82 99 1.2E-33 T 26-04-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS05910 c5b78076a623e674974f524674ede90d 249 PRINTS PR00395 Ribosomal protein S2 signature 1 19 1.2E-33 T 26-04-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS05910 c5b78076a623e674974f524674ede90d 249 PRINTS PR00395 Ribosomal protein S2 signature 32 41 1.2E-33 T 26-04-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS05910 c5b78076a623e674974f524674ede90d 249 PRINTS PR00395 Ribosomal protein S2 signature 153 170 1.2E-33 T 26-04-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS05910 c5b78076a623e674974f524674ede90d 249 PRINTS PR00395 Ribosomal protein S2 signature 191 205 1.2E-33 T 26-04-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS05910 c5b78076a623e674974f524674ede90d 249 PRINTS PR00395 Ribosomal protein S2 signature 170 181 1.2E-33 T 26-04-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS05910 c5b78076a623e674974f524674ede90d 249 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 1 221 6.7E-95 T 26-04-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 A4V04_RS05910 c5b78076a623e674974f524674ede90d 249 Pfam PF00318 Ribosomal protein S2 4 219 9.6E-91 T 26-04-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS05910 c5b78076a623e674974f524674ede90d 249 Gene3D G3DSA:1.10.287.610 95 147 1.5E-21 T 26-04-2017 A4V04_RS05910 c5b78076a623e674974f524674ede90d 249 Gene3D G3DSA:3.40.50.10490 18 94 8.8E-64 T 26-04-2017 A4V04_RS05910 c5b78076a623e674974f524674ede90d 249 Gene3D G3DSA:3.40.50.10490 153 244 8.8E-64 T 26-04-2017 A4V04_RS00250 1bece1823ea0b9d0be0334ae93df722c 141 Gene3D G3DSA:3.30.70.141 1 138 2.2E-59 T 26-04-2017 A4V04_RS00250 1bece1823ea0b9d0be0334ae93df722c 141 Pfam PF00334 Nucleoside diphosphate kinase 4 136 2.9E-55 T 26-04-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4V04_RS00250 1bece1823ea0b9d0be0334ae93df722c 141 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 26-04-2017 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4V04_RS00250 1bece1823ea0b9d0be0334ae93df722c 141 SUPERFAMILY SSF54919 1 139 4.32E-58 T 26-04-2017 A4V04_RS00250 1bece1823ea0b9d0be0334ae93df722c 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 2.6E-38 T 26-04-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4V04_RS00250 1bece1823ea0b9d0be0334ae93df722c 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 2.6E-38 T 26-04-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4V04_RS00250 1bece1823ea0b9d0be0334ae93df722c 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 2.6E-38 T 26-04-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4V04_RS00250 1bece1823ea0b9d0be0334ae93df722c 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 2.6E-38 T 26-04-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4V04_RS00250 1bece1823ea0b9d0be0334ae93df722c 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 2.6E-38 T 26-04-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4V04_RS00250 1bece1823ea0b9d0be0334ae93df722c 141 SMART SM00562 3 140 6.7E-81 T 26-04-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4V04_RS00250 1bece1823ea0b9d0be0334ae93df722c 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 34.815 T 26-04-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4V04_RS10695 3df5b15399f6fb6fc5f87804ef74c892 355 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 141 157 - T 26-04-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4V04_RS10695 3df5b15399f6fb6fc5f87804ef74c892 355 Gene3D G3DSA:3.20.20.210 4 353 7.6E-143 T 26-04-2017 A4V04_RS10695 3df5b15399f6fb6fc5f87804ef74c892 355 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 21 30 - T 26-04-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4V04_RS10695 3df5b15399f6fb6fc5f87804ef74c892 355 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 5 350 48.412 T 26-04-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4V04_RS10695 3df5b15399f6fb6fc5f87804ef74c892 355 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 4 349 3.5E-131 T 26-04-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4V04_RS10695 3df5b15399f6fb6fc5f87804ef74c892 355 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 8 348 4.6E-126 T 26-04-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4V04_RS10695 3df5b15399f6fb6fc5f87804ef74c892 355 SUPERFAMILY SSF51726 4 353 5.76E-112 T 26-04-2017 A4V04_RS00795 65ad3f1f08722e26303324b7410deafa 67 SMART SM00357 3 67 9.7E-29 T 26-04-2017 IPR011129 Cold shock protein GO:0003676 A4V04_RS00795 65ad3f1f08722e26303324b7410deafa 67 SUPERFAMILY SSF50249 1 65 5.36E-25 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS00795 65ad3f1f08722e26303324b7410deafa 67 Gene3D G3DSA:2.40.50.140 1 65 1.2E-31 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS00795 65ad3f1f08722e26303324b7410deafa 67 PRINTS PR00050 Cold shock protein signature 25 34 2.0E-16 T 26-04-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4V04_RS00795 65ad3f1f08722e26303324b7410deafa 67 PRINTS PR00050 Cold shock protein signature 4 19 2.0E-16 T 26-04-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4V04_RS00795 65ad3f1f08722e26303324b7410deafa 67 PRINTS PR00050 Cold shock protein signature 40 58 2.0E-16 T 26-04-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4V04_RS00795 65ad3f1f08722e26303324b7410deafa 67 PIRSF PIRSF002599 1 67 5.3E-24 T 26-04-2017 IPR012156 Cold shock, CspA GO:0003676 A4V04_RS00795 65ad3f1f08722e26303324b7410deafa 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 26-04-2017 IPR019844 Cold-shock conserved site A4V04_RS00795 65ad3f1f08722e26303324b7410deafa 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.6E-29 T 26-04-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4V04_RS08990 9111c6ef74adcc92403f2126f89fda97 242 Gene3D G3DSA:3.40.50.300 1 236 2.6E-81 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08990 9111c6ef74adcc92403f2126f89fda97 242 SMART SM00382 26 213 4.3E-16 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS08990 9111c6ef74adcc92403f2126f89fda97 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS08990 9111c6ef74adcc92403f2126f89fda97 242 Pfam PF00005 ABC transporter 17 165 8.1E-33 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS08990 9111c6ef74adcc92403f2126f89fda97 242 SUPERFAMILY SSF52540 1 235 2.18E-78 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08990 9111c6ef74adcc92403f2126f89fda97 242 PIRSF PIRSF039085 1 241 1.4E-103 T 26-04-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A4V04_RS11250 0a96cc342a73b05d10f51de568aa0da5 114 Pfam PF00237 Ribosomal protein L22p/L17e 9 107 2.3E-28 T 26-04-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A4V04_RS11250 0a96cc342a73b05d10f51de568aa0da5 114 Gene3D G3DSA:3.90.470.10 1 109 1.8E-36 T 26-04-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A4V04_RS11250 0a96cc342a73b05d10f51de568aa0da5 114 SUPERFAMILY SSF54843 1 109 8.5E-37 T 26-04-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A4V04_RS11250 0a96cc342a73b05d10f51de568aa0da5 114 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 4.3E-40 T 26-04-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11250 0a96cc342a73b05d10f51de568aa0da5 114 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 25.815 T 26-04-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11250 0a96cc342a73b05d10f51de568aa0da5 114 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 26-04-2017 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS04805 9cec5908511f88a4af81349f3753b675 401 SUPERFAMILY SSF55031 192 303 1.13E-26 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS04805 9cec5908511f88a4af81349f3753b675 401 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 23 384 1.4E-96 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS04805 9cec5908511f88a4af81349f3753b675 401 Pfam PF01546 Peptidase family M20/M25/M40 80 392 4.5E-26 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS04805 9cec5908511f88a4af81349f3753b675 401 SUPERFAMILY SSF53187 14 205 3.01E-67 T 26-04-2017 A4V04_RS04805 9cec5908511f88a4af81349f3753b675 401 SUPERFAMILY SSF53187 308 396 3.01E-67 T 26-04-2017 A4V04_RS04805 9cec5908511f88a4af81349f3753b675 401 Gene3D G3DSA:3.30.70.360 189 305 1.9E-33 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS04805 9cec5908511f88a4af81349f3753b675 401 Pfam PF07687 Peptidase dimerisation domain 197 286 1.3E-4 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS04805 9cec5908511f88a4af81349f3753b675 401 Gene3D G3DSA:3.40.630.10 11 186 8.8E-78 T 26-04-2017 A4V04_RS04805 9cec5908511f88a4af81349f3753b675 401 Gene3D G3DSA:3.40.630.10 306 396 8.8E-78 T 26-04-2017 A4V04_RS04805 9cec5908511f88a4af81349f3753b675 401 PIRSF PIRSF005962 6 399 1.7E-106 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS08675 50669a0191c5120182590cac7d932821 517 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 60 457 6.5E-85 T 26-04-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 A4V04_RS08675 50669a0191c5120182590cac7d932821 517 Pfam PF00795 Carbon-nitrogen hydrolase 267 467 5.5E-18 T 26-04-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4V04_RS08675 50669a0191c5120182590cac7d932821 517 Gene3D G3DSA:3.60.110.10 247 464 1.2E-18 T 26-04-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4V04_RS08675 50669a0191c5120182590cac7d932821 517 SUPERFAMILY SSF56317 225 471 1.57E-28 T 26-04-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4V04_RS08675 50669a0191c5120182590cac7d932821 517 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 7 495 20.281 T 26-04-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 A4V04_RS09690 6d6ae5c55f4308cf9ed2a6aabcbe2c89 343 Gene3D G3DSA:3.20.20.70 2 341 2.7E-66 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS09690 6d6ae5c55f4308cf9ed2a6aabcbe2c89 343 SUPERFAMILY SSF51395 39 340 2.2E-46 T 26-04-2017 A4V04_RS09690 6d6ae5c55f4308cf9ed2a6aabcbe2c89 343 Pfam PF01070 FMN-dependent dehydrogenase 190 339 4.0E-44 T 26-04-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 A4V04_RS09535 5f083c08b46f0bb46ef649bd60dedc2f 156 PIRSF PIRSF029256 1 156 1.7E-61 T 26-04-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 A4V04_RS09535 5f083c08b46f0bb46ef649bd60dedc2f 156 Pfam PF00588 SpoU rRNA Methylase family 2 144 1.2E-33 T 26-04-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4V04_RS09535 5f083c08b46f0bb46ef649bd60dedc2f 156 SUPERFAMILY SSF75217 1 154 1.18E-42 T 26-04-2017 IPR029028 Alpha/beta knot methyltransferases A4V04_RS09535 5f083c08b46f0bb46ef649bd60dedc2f 156 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 153 31.679 T 26-04-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 A4V04_RS09535 5f083c08b46f0bb46ef649bd60dedc2f 156 Gene3D G3DSA:3.40.1280.10 1 155 7.2E-63 T 26-04-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4V04_RS12015 1727af19e78e2748a0af99fe54270e5d 358 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 187 353 6.9E-37 T 26-04-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 A4V04_RS12015 1727af19e78e2748a0af99fe54270e5d 358 Gene3D G3DSA:3.40.50.2000 1 198 4.6E-56 T 26-04-2017 A4V04_RS12015 1727af19e78e2748a0af99fe54270e5d 358 Gene3D G3DSA:3.40.50.2000 255 337 1.7E-7 T 26-04-2017 A4V04_RS12015 1727af19e78e2748a0af99fe54270e5d 358 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 6 134 3.1E-29 T 26-04-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4V04_RS12015 1727af19e78e2748a0af99fe54270e5d 358 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 3 353 2.5E-93 T 26-04-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4V04_RS12015 1727af19e78e2748a0af99fe54270e5d 358 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 357 31.539 T 26-04-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4V04_RS12015 1727af19e78e2748a0af99fe54270e5d 358 SUPERFAMILY SSF53756 3 356 3.81E-104 T 26-04-2017 A4V04_RS07640 1ba016cb531a400b164d2a5a87fdd256 331 PIRSF PIRSF500176 3 330 3.7E-85 T 26-04-2017 A4V04_RS07640 1ba016cb531a400b164d2a5a87fdd256 331 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 85 95 - T 26-04-2017 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A4V04_RS07640 1ba016cb531a400b164d2a5a87fdd256 331 Gene3D G3DSA:3.40.50.1170 4 212 9.7E-64 T 26-04-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A4V04_RS07640 1ba016cb531a400b164d2a5a87fdd256 331 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 9 17 - T 26-04-2017 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A4V04_RS07640 1ba016cb531a400b164d2a5a87fdd256 331 PIRSF PIRSF001220 1 330 1.5E-89 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS07640 1ba016cb531a400b164d2a5a87fdd256 331 SMART SM00870 6 322 6.2E-113 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS07640 1ba016cb531a400b164d2a5a87fdd256 331 PRINTS PR00139 Asparaginase/glutaminase family signature 7 18 8.8E-17 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS07640 1ba016cb531a400b164d2a5a87fdd256 331 PRINTS PR00139 Asparaginase/glutaminase family signature 84 102 8.8E-17 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS07640 1ba016cb531a400b164d2a5a87fdd256 331 PRINTS PR00139 Asparaginase/glutaminase family signature 257 275 8.8E-17 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS07640 1ba016cb531a400b164d2a5a87fdd256 331 Gene3D G3DSA:3.40.50.40 213 319 2.5E-27 T 26-04-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 A4V04_RS07640 1ba016cb531a400b164d2a5a87fdd256 331 Pfam PF00710 Asparaginase, N-terminal 6 195 2.1E-53 T 26-04-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A4V04_RS07640 1ba016cb531a400b164d2a5a87fdd256 331 SUPERFAMILY SSF53774 2 326 5.1E-92 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 Hamap MF_00098 Methionine--tRNA ligase [metG]. 4 557 37.147 T 26-04-2017 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 Gene3D G3DSA:3.40.50.620 4 142 1.4E-78 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 Gene3D G3DSA:3.40.50.620 181 388 1.4E-78 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 PRINTS PR01041 Methionyl-tRNA synthetase signature 297 312 9.6E-20 T 26-04-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 9.6E-20 T 26-04-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 PRINTS PR01041 Methionyl-tRNA synthetase signature 393 404 9.6E-20 T 26-04-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 9.6E-20 T 26-04-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 PRINTS PR01041 Methionyl-tRNA synthetase signature 259 270 9.6E-20 T 26-04-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 9.6E-20 T 26-04-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 SUPERFAMILY SSF57770 140 174 4.19E-12 T 26-04-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 Pfam PF08264 Anticodon-binding domain of tRNA 427 513 4.6E-6 T 26-04-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 Gene3D G3DSA:1.10.730.10 389 545 6.3E-42 T 26-04-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 Gene3D G3DSA:2.40.50.140 588 699 2.0E-41 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 Pfam PF09334 tRNA synthetases class I (M) 7 405 5.7E-135 T 26-04-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 Gene3D G3DSA:2.20.28.20 143 174 4.2E-18 T 26-04-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 13 24 - T 26-04-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 Pfam PF01588 Putative tRNA binding domain 601 696 3.2E-26 T 26-04-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 SUPERFAMILY SSF50249 594 699 9.3E-34 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 563 699 3.4E-41 T 26-04-2017 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 SUPERFAMILY SSF47323 395 609 6.73E-40 T 26-04-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 SUPERFAMILY SSF52374 174 396 8.21E-89 T 26-04-2017 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 SUPERFAMILY SSF52374 3 139 8.21E-89 T 26-04-2017 A4V04_RS08575 f6ffa152dab586472136deabb78aef36 700 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 7 543 3.0E-159 T 26-04-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4V04_RS02610 e330369a2ed67fc6d75a3f6144a42765 323 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 21 322 2.9E-52 T 26-04-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A4V04_RS02610 e330369a2ed67fc6d75a3f6144a42765 323 SUPERFAMILY SSF51735 21 169 4.48E-8 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS02610 e330369a2ed67fc6d75a3f6144a42765 323 SUPERFAMILY SSF48179 196 320 1.8E-21 T 26-04-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4V04_RS02610 e330369a2ed67fc6d75a3f6144a42765 323 Gene3D G3DSA:3.40.50.720 21 204 3.1E-31 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS02610 e330369a2ed67fc6d75a3f6144a42765 323 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 196 320 3.6E-24 T 26-04-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A4V04_RS02610 e330369a2ed67fc6d75a3f6144a42765 323 Pfam PF02558 Ketopantoate reductase PanE/ApbA 22 141 2.8E-20 T 26-04-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A4V04_RS02610 e330369a2ed67fc6d75a3f6144a42765 323 Gene3D G3DSA:1.10.1040.10 205 321 5.2E-27 T 26-04-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4V04_RS10245 93b40e57cc49bf06b69e6f6b26207320 578 Gene3D G3DSA:3.40.50.300 208 372 3.7E-50 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10245 93b40e57cc49bf06b69e6f6b26207320 578 Pfam PF00270 DEAD/DEAH box helicase 28 194 4.9E-49 T 26-04-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4V04_RS10245 93b40e57cc49bf06b69e6f6b26207320 578 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 26-04-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A4V04_RS10245 93b40e57cc49bf06b69e6f6b26207320 578 Gene3D G3DSA:3.40.50.300 6 207 7.4E-76 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10245 93b40e57cc49bf06b69e6f6b26207320 578 SUPERFAMILY SSF52540 73 363 7.85E-72 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10245 93b40e57cc49bf06b69e6f6b26207320 578 Pfam PF03880 DbpA RNA binding domain 472 542 1.2E-22 T 26-04-2017 IPR005580 DbpA, RNA-binding domain A4V04_RS10245 93b40e57cc49bf06b69e6f6b26207320 578 SMART SM00487 23 220 2.2E-60 T 26-04-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4V04_RS10245 93b40e57cc49bf06b69e6f6b26207320 578 Pfam PF00271 Helicase conserved C-terminal domain 240 342 4.7E-27 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS10245 93b40e57cc49bf06b69e6f6b26207320 578 SMART SM00490 261 342 3.1E-34 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS08900 554444d422969f88e78ae091b185c29b 235 Pfam PF00005 ABC transporter 28 176 4.9E-32 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS08900 554444d422969f88e78ae091b185c29b 235 Gene3D G3DSA:3.40.50.300 7 228 4.3E-67 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08900 554444d422969f88e78ae091b185c29b 235 SUPERFAMILY SSF52540 8 229 4.37E-72 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08900 554444d422969f88e78ae091b185c29b 235 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS08900 554444d422969f88e78ae091b185c29b 235 SMART SM00382 37 225 5.5E-12 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS00255 b95a5d8dec342ee2a6427c7ea3743962 381 Pfam PF04055 Radical SAM superfamily 113 284 5.4E-18 T 26-04-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 A4V04_RS00255 b95a5d8dec342ee2a6427c7ea3743962 381 Gene3D G3DSA:3.20.20.70 109 325 1.1E-14 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS00255 b95a5d8dec342ee2a6427c7ea3743962 381 SUPERFAMILY SSF102114 108 329 2.35E-15 T 26-04-2017 A4V04_RS00255 b95a5d8dec342ee2a6427c7ea3743962 381 Pfam PF13394 4Fe-4S single cluster domain 117 217 6.5E-5 T 26-04-2017 A4V04_RS00255 b95a5d8dec342ee2a6427c7ea3743962 381 PIRSF PIRSF006004 5 372 1.1E-146 T 26-04-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS00255 b95a5d8dec342ee2a6427c7ea3743962 381 SMART SM00729 109 327 0.0083 T 26-04-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4V04_RS00255 b95a5d8dec342ee2a6427c7ea3743962 381 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 10 359 73.019 T 26-04-2017 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS00255 b95a5d8dec342ee2a6427c7ea3743962 381 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 8 363 2.4E-134 T 26-04-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS06830 a792f9ebbfeb20c7a12603adf7507497 187 Pfam PF11939 Protein of unknown function (DUF3457) 14 181 2.4E-50 T 26-04-2017 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE A4V04_RS06830 a792f9ebbfeb20c7a12603adf7507497 187 ProDom PD008308 HUPJ HYDROGENASE EXPRESSION/FORMATION HYDROGENASE-2 HYBE COMPONENT OPERON ELECTRON METAL-BINDING IRON 18 181 3.0E-21 T 26-04-2017 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE A4V04_RS06830 a792f9ebbfeb20c7a12603adf7507497 187 TIGRFAM TIGR03993 hydrog_HybE: [NiFe] hydrogenase assembly chaperone, HybE family 17 180 1.8E-41 T 26-04-2017 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE A4V04_RS11390 46269e4a88f88ce08613b5a93fc9dc93 499 Pfam PF14698 Argininosuccinate lyase C-terminal 366 444 2.3E-10 T 26-04-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS11390 46269e4a88f88ce08613b5a93fc9dc93 499 Pfam PF00206 Lyase 76 301 1.2E-27 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS11390 46269e4a88f88ce08613b5a93fc9dc93 499 Gene3D G3DSA:1.10.40.30 373 445 1.9E-12 T 26-04-2017 A4V04_RS11390 46269e4a88f88ce08613b5a93fc9dc93 499 SUPERFAMILY SSF48557 29 466 2.36E-74 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS11390 46269e4a88f88ce08613b5a93fc9dc93 499 Gene3D G3DSA:1.20.200.10 104 372 1.0E-48 T 26-04-2017 A4V04_RS11390 46269e4a88f88ce08613b5a93fc9dc93 499 PRINTS PR00145 Argininosuccinate lyase family signature 98 120 7.5E-14 T 26-04-2017 A4V04_RS11390 46269e4a88f88ce08613b5a93fc9dc93 499 PRINTS PR00145 Argininosuccinate lyase family signature 139 159 7.5E-14 T 26-04-2017 A4V04_RS11390 46269e4a88f88ce08613b5a93fc9dc93 499 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 7.5E-14 T 26-04-2017 A4V04_RS11390 46269e4a88f88ce08613b5a93fc9dc93 499 PRINTS PR00145 Argininosuccinate lyase family signature 190 206 7.5E-14 T 26-04-2017 A4V04_RS11390 46269e4a88f88ce08613b5a93fc9dc93 499 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 2.4E-6 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS11390 46269e4a88f88ce08613b5a93fc9dc93 499 PRINTS PR00149 Fumarate lyase superfamily signature 99 117 2.4E-6 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS11390 46269e4a88f88ce08613b5a93fc9dc93 499 PRINTS PR00149 Fumarate lyase superfamily signature 144 162 2.4E-6 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS11390 46269e4a88f88ce08613b5a93fc9dc93 499 PRINTS PR00149 Fumarate lyase superfamily signature 230 257 2.4E-6 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS08835 6d47cf91e666bba8303db2b5281e7262 408 Gene3D G3DSA:1.20.1250.20 7 189 2.9E-16 T 26-04-2017 A4V04_RS08835 6d47cf91e666bba8303db2b5281e7262 408 Gene3D G3DSA:1.20.1250.20 221 406 2.4E-22 T 26-04-2017 A4V04_RS08835 6d47cf91e666bba8303db2b5281e7262 408 SUPERFAMILY SSF103473 1 406 3.4E-50 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS08835 6d47cf91e666bba8303db2b5281e7262 408 Pfam PF07690 Major Facilitator Superfamily 39 367 3.8E-29 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS03035 c10b66371ba6682a16985d0a8969824a 445 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 7 443 57.179 T 26-04-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 A4V04_RS03035 c10b66371ba6682a16985d0a8969824a 445 SUPERFAMILY SSF102114 100 371 9.81E-45 T 26-04-2017 A4V04_RS03035 c10b66371ba6682a16985d0a8969824a 445 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 9 441 2.5E-99 T 26-04-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 A4V04_RS03035 c10b66371ba6682a16985d0a8969824a 445 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 8 440 1.1E-165 T 26-04-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 A4V04_RS03035 c10b66371ba6682a16985d0a8969824a 445 Pfam PF04055 Radical SAM superfamily 148 324 3.4E-27 T 26-04-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 A4V04_RS03035 c10b66371ba6682a16985d0a8969824a 445 SMART SM00729 142 366 1.5E-44 T 26-04-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4V04_RS03035 c10b66371ba6682a16985d0a8969824a 445 Gene3D G3DSA:3.80.30.20 140 378 7.7E-65 T 26-04-2017 IPR023404 Radical SAM, alpha/beta horseshoe A4V04_RS03035 c10b66371ba6682a16985d0a8969824a 445 Pfam PF00919 Uncharacterized protein family UPF0004 8 89 1.5E-19 T 26-04-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 A4V04_RS03035 c10b66371ba6682a16985d0a8969824a 445 Gene3D G3DSA:2.40.50.140 381 443 7.6E-23 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS03035 c10b66371ba6682a16985d0a8969824a 445 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 146 166 - T 26-04-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 A4V04_RS07760 c19d425a9cc56c22e587ea2c550b2c43 247 PIRSF PIRSF005763 8 247 6.2E-52 T 26-04-2017 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 A4V04_RS07760 c19d425a9cc56c22e587ea2c550b2c43 247 SUPERFAMILY SSF46785 15 97 1.12E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07760 c19d425a9cc56c22e587ea2c550b2c43 247 Gene3D G3DSA:1.10.10.10 13 113 1.4E-29 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07760 c19d425a9cc56c22e587ea2c550b2c43 247 SUPERFAMILY SSF50331 113 179 1.87E-12 T 26-04-2017 IPR008995 Molybdate/tungstate binding, C-terminal A4V04_RS07760 c19d425a9cc56c22e587ea2c550b2c43 247 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 77 1.9E-14 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS07760 c19d425a9cc56c22e587ea2c550b2c43 247 Pfam PF03459 TOBE domain 116 174 6.5E-10 T 26-04-2017 IPR005116 Transport-associated OB, type 1 A4V04_RS07760 c19d425a9cc56c22e587ea2c550b2c43 247 Gene3D G3DSA:2.40.50.100 114 174 2.3E-15 T 26-04-2017 A4V04_RS06890 d3ab895ce2ddfef10ec263fbd1e04f80 632 Pfam PF13721 SecD export protein N-terminal TM region 1 114 2.1E-33 T 26-04-2017 IPR027398 SecD export protein N-terminal TM domain A4V04_RS06890 d3ab895ce2ddfef10ec263fbd1e04f80 632 Pfam PF02355 Protein export membrane protein 435 605 1.6E-19 T 26-04-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A4V04_RS06890 d3ab895ce2ddfef10ec263fbd1e04f80 632 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 361 595 4.7E-74 T 26-04-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4V04_RS06890 d3ab895ce2ddfef10ec263fbd1e04f80 632 Pfam PF07549 SecD/SecF GG Motif 129 151 5.7E-5 T 26-04-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A4V04_RS06890 d3ab895ce2ddfef10ec263fbd1e04f80 632 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 134 602 2.6E-148 T 26-04-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A4V04_RS06890 d3ab895ce2ddfef10ec263fbd1e04f80 632 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 617 47.964 T 26-04-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A4V04_RS06890 d3ab895ce2ddfef10ec263fbd1e04f80 632 Gene3D G3DSA:1.20.1640.10 447 612 4.3E-21 T 26-04-2017 A4V04_RS06890 d3ab895ce2ddfef10ec263fbd1e04f80 632 SUPERFAMILY SSF82866 412 610 6.54E-38 T 26-04-2017 A4V04_RS01615 dfc5c086cd0f8303d1b090fbfe057f2b 484 SUPERFAMILY SSF48557 2 465 1.57E-80 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS01615 dfc5c086cd0f8303d1b090fbfe057f2b 484 Gene3D G3DSA:1.10.275.10 1 135 2.0E-50 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS01615 dfc5c086cd0f8303d1b090fbfe057f2b 484 PRINTS PR00149 Fumarate lyase superfamily signature 131 149 1.8E-14 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01615 dfc5c086cd0f8303d1b090fbfe057f2b 484 PRINTS PR00149 Fumarate lyase superfamily signature 276 303 1.8E-14 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01615 dfc5c086cd0f8303d1b090fbfe057f2b 484 PRINTS PR00149 Fumarate lyase superfamily signature 176 194 1.8E-14 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01615 dfc5c086cd0f8303d1b090fbfe057f2b 484 Gene3D G3DSA:1.10.40.30 415 468 4.0E-9 T 26-04-2017 A4V04_RS01615 dfc5c086cd0f8303d1b090fbfe057f2b 484 Gene3D G3DSA:1.20.200.10 136 407 4.2E-53 T 26-04-2017 A4V04_RS01615 dfc5c086cd0f8303d1b090fbfe057f2b 484 Pfam PF00206 Lyase 9 322 2.3E-62 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS01615 dfc5c086cd0f8303d1b090fbfe057f2b 484 Pfam PF10415 Fumarase C C-terminus 415 465 1.2E-9 T 26-04-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS09080 a2d3581d65c5d158333bdc1c0fbddfaf 115 Pfam PF02256 Iron hydrogenase small subunit 46 104 3.1E-12 T 26-04-2017 IPR003149 Iron hydrogenase, small subunit A4V04_RS09080 a2d3581d65c5d158333bdc1c0fbddfaf 115 SMART SM00902 43 105 0.0089 T 26-04-2017 IPR003149 Iron hydrogenase, small subunit A4V04_RS09080 a2d3581d65c5d158333bdc1c0fbddfaf 115 SUPERFAMILY SSF48674 46 106 1.7E-10 T 26-04-2017 IPR008953 Iron hydrogenase, small subunit HydB-type GO:0005506|GO:0008901|GO:0009055|GO:0042597|GO:0051536 MetaCyc: PWY-6759|MetaCyc: PWY-6785 A4V04_RS09080 a2d3581d65c5d158333bdc1c0fbddfaf 115 Gene3D G3DSA:4.10.260.20 46 113 5.2E-16 T 26-04-2017 IPR003149 Iron hydrogenase, small subunit A4V04_RS10350 cf0af5d23bd55c4141f32431dc648a61 592 SMART SM00387 478 587 1.6E-7 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10350 cf0af5d23bd55c4141f32431dc648a61 592 SUPERFAMILY SSF53850 47 279 1.81E-15 T 26-04-2017 A4V04_RS10350 cf0af5d23bd55c4141f32431dc648a61 592 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 44 270 2.0E-27 T 26-04-2017 A4V04_RS10350 cf0af5d23bd55c4141f32431dc648a61 592 SMART SM00388 366 438 0.0015 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10350 cf0af5d23bd55c4141f32431dc648a61 592 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 478 576 2.8E-11 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10350 cf0af5d23bd55c4141f32431dc648a61 592 SUPERFAMILY SSF47384 358 436 8.04E-6 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10350 cf0af5d23bd55c4141f32431dc648a61 592 SUPERFAMILY SSF55874 429 583 8.91E-21 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10350 cf0af5d23bd55c4141f32431dc648a61 592 Gene3D G3DSA:3.30.565.10 441 583 9.0E-21 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 SUPERFAMILY SSF50447 453 552 2.91E-17 T 26-04-2017 IPR009000 Translation protein, beta-barrel domain A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 SUPERFAMILY SSF55681 2 252 1.81E-107 T 26-04-2017 A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 653 695 5.2E-18 T 26-04-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 Pfam PF02272 DHHA1 domain 799 867 3.0E-12 T 26-04-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 SMART SM00863 653 695 4.8E-20 T 26-04-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 SUPERFAMILY SSF101353 253 444 5.62E-56 T 26-04-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 Pfam PF01411 tRNA synthetases class II (A) 6 555 5.0E-213 T 26-04-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 75 86 2.0E-30 T 26-04-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 206 217 2.0E-30 T 26-04-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 308 321 2.0E-30 T 26-04-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 233 246 2.0E-30 T 26-04-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 284 300 2.0E-30 T 26-04-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 874 187.417 T 26-04-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 853 5.6E-303 T 26-04-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 Gene3D G3DSA:3.30.930.10 2 248 1.2E-123 T 26-04-2017 A4V04_RS00745 69e332858ad520f2ab5941a341f0bf56 875 SUPERFAMILY SSF55186 552 711 8.11E-50 T 26-04-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 A4V04_RS11240 f0e9d7062023a2b9847fc1a3438e2601 275 Gene3D G3DSA:2.30.30.30 118 195 6.1E-35 T 26-04-2017 IPR014722 Ribosomal protein L2 domain 2 A4V04_RS11240 f0e9d7062023a2b9847fc1a3438e2601 275 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 273 1.2E-130 T 26-04-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11240 f0e9d7062023a2b9847fc1a3438e2601 275 SUPERFAMILY SSF50249 3 125 2.98E-49 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS11240 f0e9d7062023a2b9847fc1a3438e2601 275 Gene3D G3DSA:2.40.50.140 1 114 2.2E-49 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS11240 f0e9d7062023a2b9847fc1a3438e2601 275 Gene3D G3DSA:4.10.950.10 196 272 1.8E-34 T 26-04-2017 IPR014726 Ribosomal protein L2, domain 3 A4V04_RS11240 f0e9d7062023a2b9847fc1a3438e2601 275 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.741 T 26-04-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11240 f0e9d7062023a2b9847fc1a3438e2601 275 PIRSF PIRSF002158 8 275 2.9E-102 T 26-04-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11240 f0e9d7062023a2b9847fc1a3438e2601 275 SMART SM01383 42 118 9.6E-47 T 26-04-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11240 f0e9d7062023a2b9847fc1a3438e2601 275 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 3.2E-34 T 26-04-2017 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11240 f0e9d7062023a2b9847fc1a3438e2601 275 SMART SM01382 124 252 1.6E-90 T 26-04-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A4V04_RS11240 f0e9d7062023a2b9847fc1a3438e2601 275 SUPERFAMILY SSF50104 127 272 1.44E-60 T 26-04-2017 IPR008991 Translation protein SH3-like domain A4V04_RS11240 f0e9d7062023a2b9847fc1a3438e2601 275 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 1.2E-56 T 26-04-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A4V04_RS11240 f0e9d7062023a2b9847fc1a3438e2601 275 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 26-04-2017 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 Gene3D G3DSA:3.40.50.720 6 254 4.2E-86 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.8E-13 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 1.8E-13 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 1.8E-13 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 26-04-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 193 3.2E-6 T 26-04-2017 A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 SUPERFAMILY SSF51735 12 253 5.72E-82 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 16 252 1.1E-97 T 26-04-2017 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 3.4E-45 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 3.4E-45 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 3.4E-45 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 3.4E-45 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 3.4E-45 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 3.4E-45 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS02885 92bd730753f9d2f68fc3509a49c6e222 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 252 1.1E-64 T 26-04-2017 A4V04_RS04665 41d29f4628900d6f72dcd0b7340c6715 316 Pfam PF00753 Metallo-beta-lactamase superfamily 88 210 1.6E-15 T 26-04-2017 IPR001279 Metallo-beta-lactamase A4V04_RS04665 41d29f4628900d6f72dcd0b7340c6715 316 SUPERFAMILY SSF56281 71 259 2.16E-35 T 26-04-2017 IPR001279 Metallo-beta-lactamase A4V04_RS04665 41d29f4628900d6f72dcd0b7340c6715 316 Gene3D G3DSA:3.60.15.10 69 312 7.4E-37 T 26-04-2017 IPR001279 Metallo-beta-lactamase A4V04_RS04665 41d29f4628900d6f72dcd0b7340c6715 316 SMART SM00849 86 266 4.4E-16 T 26-04-2017 IPR001279 Metallo-beta-lactamase A4V04_RS12110 2304df41820963d7f8e3d9ec71415899 270 SMART SM00934 17 254 6.8E-52 T 26-04-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4V04_RS12110 2304df41820963d7f8e3d9ec71415899 270 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 3 254 9.8E-75 T 26-04-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 A4V04_RS12110 2304df41820963d7f8e3d9ec71415899 270 Gene3D G3DSA:3.20.20.70 8 258 6.1E-66 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS12110 2304df41820963d7f8e3d9ec71415899 270 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 267 34.29 T 26-04-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 A4V04_RS12110 2304df41820963d7f8e3d9ec71415899 270 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 26-04-2017 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4V04_RS12110 2304df41820963d7f8e3d9ec71415899 270 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 253 6.5E-33 T 26-04-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4V04_RS12110 2304df41820963d7f8e3d9ec71415899 270 SUPERFAMILY SSF51366 3 260 1.22E-76 T 26-04-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A4V04_RS11120 edda37b6f81c4f832b55f7724e679263 122 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 68 121 1.8E-16 T 26-04-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 A4V04_RS11120 edda37b6f81c4f832b55f7724e679263 122 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 69 121 4.1E-18 T 26-04-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4V04_RS11120 edda37b6f81c4f832b55f7724e679263 122 Gene3D G3DSA:1.20.5.1030 64 122 4.2E-22 T 26-04-2017 A4V04_RS11120 edda37b6f81c4f832b55f7724e679263 122 Hamap MF_00422 Protein translocase subunit SecE [secE]. 62 120 11.931 T 26-04-2017 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4V04_RS11015 b7f661720b067f73c4cb8020fcad5811 751 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 309 432 1.3E-10 T 26-04-2017 IPR003959 ATPase, AAA-type, core GO:0005524 A4V04_RS11015 b7f661720b067f73c4cb8020fcad5811 751 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 546 667 7.4E-30 T 26-04-2017 IPR003959 ATPase, AAA-type, core GO:0005524 A4V04_RS11015 b7f661720b067f73c4cb8020fcad5811 751 SUPERFAMILY SSF52540 246 478 3.54E-20 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11015 b7f661720b067f73c4cb8020fcad5811 751 SMART SM00382 305 436 1.1E-7 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS11015 b7f661720b067f73c4cb8020fcad5811 751 SMART SM00382 542 673 3.7E-13 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS11015 b7f661720b067f73c4cb8020fcad5811 751 SUPERFAMILY SSF52540 530 723 1.21E-36 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11015 b7f661720b067f73c4cb8020fcad5811 751 Gene3D G3DSA:3.40.50.300 294 461 2.9E-17 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11015 b7f661720b067f73c4cb8020fcad5811 751 Gene3D G3DSA:3.40.50.300 539 708 8.0E-37 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08670 eea9818f0d4237e346072e8e767e6b25 202 SUPERFAMILY SSF52833 40 187 3.22E-31 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS08670 eea9818f0d4237e346072e8e767e6b25 202 Pfam PF00578 AhpC/TSA family 54 166 1.9E-16 T 26-04-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4V04_RS08670 eea9818f0d4237e346072e8e767e6b25 202 Gene3D G3DSA:3.40.30.10 3 196 1.2E-38 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS13110 5eb1d764c5d6867d4748261b72f77a8b 1186 SUPERFAMILY SSF52540 399 840 1.03E-40 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13110 5eb1d764c5d6867d4748261b72f77a8b 1186 Gene3D G3DSA:1.10.10.160 91 200 2.3E-9 T 26-04-2017 IPR013986 DExx box DNA helicase domain A4V04_RS13110 5eb1d764c5d6867d4748261b72f77a8b 1186 SUPERFAMILY SSF52540 1 293 4.12E-27 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13110 5eb1d764c5d6867d4748261b72f77a8b 1186 Gene3D G3DSA:3.40.50.300 394 491 5.2E-5 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13110 5eb1d764c5d6867d4748261b72f77a8b 1186 Gene3D G3DSA:3.40.50.300 703 739 5.2E-5 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13110 5eb1d764c5d6867d4748261b72f77a8b 1186 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 2 843 2.0E-115 T 26-04-2017 A4V04_RS01480 b047cd362f873d06003a05b5fdf4bf71 354 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 5 354 3.4E-144 T 26-04-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A4V04_RS01480 b047cd362f873d06003a05b5fdf4bf71 354 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 354 45.374 T 26-04-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A4V04_RS01480 b047cd362f873d06003a05b5fdf4bf71 354 Gene3D G3DSA:3.40.640.10 17 251 1.1E-90 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS01480 b047cd362f873d06003a05b5fdf4bf71 354 Pfam PF00266 Aminotransferase class-V 5 342 1.7E-48 T 26-04-2017 IPR000192 Aminotransferase class V domain A4V04_RS01480 b047cd362f873d06003a05b5fdf4bf71 354 SUPERFAMILY SSF53383 1 351 1.42E-102 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS01480 b047cd362f873d06003a05b5fdf4bf71 354 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 181 200 - T 26-04-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A4V04_RS01480 b047cd362f873d06003a05b5fdf4bf71 354 PIRSF PIRSF000525 1 354 4.1E-140 T 26-04-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A4V04_RS01480 b047cd362f873d06003a05b5fdf4bf71 354 Gene3D G3DSA:3.90.1150.10 252 353 5.2E-40 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS02435 af44e1a0e23b973790fe5440e15178f7 309 SUPERFAMILY SSF103481 229 297 1.44E-11 T 26-04-2017 A4V04_RS02435 af44e1a0e23b973790fe5440e15178f7 309 SUPERFAMILY SSF103481 53 152 1.03E-8 T 26-04-2017 A4V04_RS02435 af44e1a0e23b973790fe5440e15178f7 309 Pfam PF00892 EamA-like transporter family 17 152 2.4E-16 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS02435 af44e1a0e23b973790fe5440e15178f7 309 Pfam PF00892 EamA-like transporter family 166 293 1.2E-16 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS08875 662a9170cfdcbde97ab169d7d050f474 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 44 63 4.4E-5 T 26-04-2017 A4V04_RS08875 662a9170cfdcbde97ab169d7d050f474 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 438 460 4.4E-5 T 26-04-2017 A4V04_RS08875 662a9170cfdcbde97ab169d7d050f474 496 SUPERFAMILY SSF51905 30 288 8.08E-44 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08875 662a9170cfdcbde97ab169d7d050f474 496 SUPERFAMILY SSF51905 433 493 8.08E-44 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08875 662a9170cfdcbde97ab169d7d050f474 496 Pfam PF00890 FAD binding domain 43 463 4.5E-52 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08875 662a9170cfdcbde97ab169d7d050f474 496 Gene3D G3DSA:3.50.50.60 430 492 4.3E-76 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08875 662a9170cfdcbde97ab169d7d050f474 496 Gene3D G3DSA:3.50.50.60 29 278 4.3E-76 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08875 662a9170cfdcbde97ab169d7d050f474 496 Gene3D G3DSA:3.90.700.10 298 423 2.3E-19 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08875 662a9170cfdcbde97ab169d7d050f474 496 SUPERFAMILY SSF56425 293 433 1.12E-19 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10200 85cce721d6e70eedc1ad41a751e03c99 506 Gene3D G3DSA:3.90.700.10 309 438 1.9E-27 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10200 85cce721d6e70eedc1ad41a751e03c99 506 Pfam PF00890 FAD binding domain 43 487 3.9E-71 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10200 85cce721d6e70eedc1ad41a751e03c99 506 Gene3D G3DSA:3.50.50.60 443 504 3.8E-82 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10200 85cce721d6e70eedc1ad41a751e03c99 506 Gene3D G3DSA:3.50.50.60 30 283 3.8E-82 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10200 85cce721d6e70eedc1ad41a751e03c99 506 SUPERFAMILY SSF51905 31 300 8.23E-52 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10200 85cce721d6e70eedc1ad41a751e03c99 506 SUPERFAMILY SSF51905 446 504 8.23E-52 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10200 85cce721d6e70eedc1ad41a751e03c99 506 SUPERFAMILY SSF56425 284 442 1.5E-28 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10200 85cce721d6e70eedc1ad41a751e03c99 506 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 44 63 2.0E-5 T 26-04-2017 A4V04_RS10200 85cce721d6e70eedc1ad41a751e03c99 506 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 452 474 2.0E-5 T 26-04-2017 A4V04_RS10200 85cce721d6e70eedc1ad41a751e03c99 506 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 43 499 2.5E-132 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS11895 5f7110c896ce171ae3c2456644c78000 569 Pfam PF00890 FAD binding domain 41 547 1.0E-47 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11895 5f7110c896ce171ae3c2456644c78000 569 SUPERFAMILY SSF56425 322 500 1.92E-22 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11895 5f7110c896ce171ae3c2456644c78000 569 Gene3D G3DSA:3.90.700.10 333 499 3.1E-29 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11895 5f7110c896ce171ae3c2456644c78000 569 SUPERFAMILY SSF51905 31 176 4.69E-31 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11895 5f7110c896ce171ae3c2456644c78000 569 SUPERFAMILY SSF51905 508 564 4.69E-31 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11895 5f7110c896ce171ae3c2456644c78000 569 SUPERFAMILY SSF51905 212 318 4.69E-31 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11895 5f7110c896ce171ae3c2456644c78000 569 Gene3D G3DSA:3.50.50.60 27 312 1.4E-57 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11895 5f7110c896ce171ae3c2456644c78000 569 Gene3D G3DSA:3.50.50.60 505 564 1.4E-57 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11895 5f7110c896ce171ae3c2456644c78000 569 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 23 0.0013 T 26-04-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A4V04_RS09020 ed6027b32b083bad3160ff01fe28c6bd 453 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 339 358 - T 26-04-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09020 ed6027b32b083bad3160ff01fe28c6bd 453 Pfam PF04552 Sigma-54, DNA binding domain 295 452 4.0E-59 T 26-04-2017 IPR007634 RNA polymerase sigma factor 54, DNA-binding A4V04_RS09020 ed6027b32b083bad3160ff01fe28c6bd 453 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 47 2.5E-17 T 26-04-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09020 ed6027b32b083bad3160ff01fe28c6bd 453 Pfam PF04963 Sigma-54 factor, core binding domain 85 278 2.0E-42 T 26-04-2017 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 A4V04_RS09020 ed6027b32b083bad3160ff01fe28c6bd 453 PIRSF PIRSF000774 1 453 2.9E-130 T 26-04-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09020 ed6027b32b083bad3160ff01fe28c6bd 453 PRINTS PR00045 Sigma-54 factor signature 351 363 7.6E-25 T 26-04-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09020 ed6027b32b083bad3160ff01fe28c6bd 453 PRINTS PR00045 Sigma-54 factor signature 158 175 7.6E-25 T 26-04-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09020 ed6027b32b083bad3160ff01fe28c6bd 453 PRINTS PR00045 Sigma-54 factor signature 367 378 7.6E-25 T 26-04-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09020 ed6027b32b083bad3160ff01fe28c6bd 453 PRINTS PR00045 Sigma-54 factor signature 427 445 7.6E-25 T 26-04-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09020 ed6027b32b083bad3160ff01fe28c6bd 453 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 432 439 - T 26-04-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A4V04_RS09020 ed6027b32b083bad3160ff01fe28c6bd 453 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 9 451 4.9E-124 T 26-04-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A4V04_RS06120 8af39dc5fa8f274782cb30ce2b2a0ff1 206 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 7 202 3.0E-16 T 26-04-2017 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 A4V04_RS06120 8af39dc5fa8f274782cb30ce2b2a0ff1 206 Gene3D G3DSA:2.50.20.10 25 204 6.7E-51 T 26-04-2017 A4V04_RS06120 8af39dc5fa8f274782cb30ce2b2a0ff1 206 SUPERFAMILY SSF89392 27 205 7.06E-44 T 26-04-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX A4V04_RS06120 8af39dc5fa8f274782cb30ce2b2a0ff1 206 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 8 205 24.964 T 26-04-2017 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 A4V04_RS06120 8af39dc5fa8f274782cb30ce2b2a0ff1 206 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 33 194 5.2E-38 T 26-04-2017 IPR004564 Outer membrane lipoprotein carrier protein LolA-like A4V04_RS05290 ee45a11eccc26edd6c5ec3832b93679c 304 Gene3D G3DSA:3.30.70.1350 231 299 6.1E-6 T 26-04-2017 IPR027470 Cation efflux protein, cytoplasmic domain A4V04_RS05290 ee45a11eccc26edd6c5ec3832b93679c 304 Pfam PF01545 Cation efflux family 34 222 4.5E-46 T 26-04-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4V04_RS05290 ee45a11eccc26edd6c5ec3832b93679c 304 SUPERFAMILY SSF160240 227 299 4.32E-11 T 26-04-2017 A4V04_RS05290 ee45a11eccc26edd6c5ec3832b93679c 304 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 29 302 1.2E-85 T 26-04-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4V04_RS05290 ee45a11eccc26edd6c5ec3832b93679c 304 Gene3D G3DSA:1.20.1510.10 29 222 3.4E-56 T 26-04-2017 IPR027469 Cation efflux protein transmembrane domain A4V04_RS05290 ee45a11eccc26edd6c5ec3832b93679c 304 SUPERFAMILY SSF161111 26 223 2.09E-52 T 26-04-2017 A4V04_RS09605 72bdc93c859f7508874d3d2c5654b3e9 505 SUPERFAMILY SSF53686 5 357 1.09E-99 T 26-04-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4V04_RS09605 72bdc93c859f7508874d3d2c5654b3e9 505 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 5 504 6.2E-243 T 26-04-2017 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A4V04_RS09605 72bdc93c859f7508874d3d2c5654b3e9 505 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 308 3.7E-77 T 26-04-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4V04_RS09605 72bdc93c859f7508874d3d2c5654b3e9 505 Gene3D G3DSA:3.40.50.1100 70 327 8.2E-82 T 26-04-2017 A4V04_RS09605 72bdc93c859f7508874d3d2c5654b3e9 505 Gene3D G3DSA:3.40.1020.10 380 504 5.5E-46 T 26-04-2017 A4V04_RS09605 72bdc93c859f7508874d3d2c5654b3e9 505 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 421 504 2.4E-25 T 26-04-2017 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A4V04_RS09605 72bdc93c859f7508874d3d2c5654b3e9 505 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 322 410 1.2E-25 T 26-04-2017 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A4V04_RS09605 72bdc93c859f7508874d3d2c5654b3e9 505 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 43 56 - T 26-04-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A4V04_RS09605 72bdc93c859f7508874d3d2c5654b3e9 505 SUPERFAMILY SSF55021 411 504 2.29E-28 T 26-04-2017 A4V04_RS04945 9b74e8800d6e04e5aa59cdae922bdad2 402 Gene3D G3DSA:3.40.50.150 255 381 7.7E-28 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS04945 9b74e8800d6e04e5aa59cdae922bdad2 402 Gene3D G3DSA:3.40.50.150 151 218 7.7E-28 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS04945 9b74e8800d6e04e5aa59cdae922bdad2 402 SMART SM00981 60 158 3.3E-21 T 26-04-2017 IPR004114 THUMP domain GO:0003723 A4V04_RS04945 9b74e8800d6e04e5aa59cdae922bdad2 402 SUPERFAMILY SSF53335 150 221 9.26E-36 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS04945 9b74e8800d6e04e5aa59cdae922bdad2 402 SUPERFAMILY SSF53335 258 379 9.26E-36 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS04945 9b74e8800d6e04e5aa59cdae922bdad2 402 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 199 210 - T 26-04-2017 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS04945 9b74e8800d6e04e5aa59cdae922bdad2 402 Pfam PF02926 THUMP domain 29 158 4.8E-12 T 26-04-2017 IPR004114 THUMP domain GO:0003723 A4V04_RS04945 9b74e8800d6e04e5aa59cdae922bdad2 402 Pfam PF01170 Putative RNA methylase family UPF0020 166 377 3.9E-46 T 26-04-2017 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS04945 9b74e8800d6e04e5aa59cdae922bdad2 402 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 309 315 - T 26-04-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4V04_RS11165 80381bf34e2073c205a2a209d3cfae72 157 SUPERFAMILY SSF47973 2 149 1.83E-62 T 26-04-2017 IPR023798 Ribosomal protein S7 domain A4V04_RS11165 80381bf34e2073c205a2a209d3cfae72 157 PIRSF PIRSF002122 3 157 1.2E-59 T 26-04-2017 IPR000235 Ribosomal protein S5/S7 GO:0006412 A4V04_RS11165 80381bf34e2073c205a2a209d3cfae72 157 Gene3D G3DSA:1.10.455.10 7 156 6.7E-65 T 26-04-2017 IPR023798 Ribosomal protein S7 domain A4V04_RS11165 80381bf34e2073c205a2a209d3cfae72 157 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.945 T 26-04-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A4V04_RS11165 80381bf34e2073c205a2a209d3cfae72 157 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 26-04-2017 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11165 80381bf34e2073c205a2a209d3cfae72 157 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 155 3.4E-65 T 26-04-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A4V04_RS11165 80381bf34e2073c205a2a209d3cfae72 157 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.5E-67 T 26-04-2017 IPR023798 Ribosomal protein S7 domain A4V04_RS11505 70a1ab7a3c2daa7834c1429a91472b6e 380 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 112 334 3.3E-97 T 26-04-2017 IPR022488 Polyphosphate kinase-2-related A4V04_RS11505 70a1ab7a3c2daa7834c1429a91472b6e 380 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 112 336 2.8E-109 T 26-04-2017 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 A4V04_RS11505 70a1ab7a3c2daa7834c1429a91472b6e 380 Gene3D G3DSA:3.40.50.300 95 343 7.9E-101 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11505 70a1ab7a3c2daa7834c1429a91472b6e 380 SUPERFAMILY SSF52540 140 326 3.65E-26 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06320 3e7d1ffaf09a4435bf83f6a108e9ef9e 247 SUPERFAMILY SSF101082 28 215 2.75E-31 T 26-04-2017 IPR023220 Type IV secretion system, VirB5-domain A4V04_RS06320 3e7d1ffaf09a4435bf83f6a108e9ef9e 247 Pfam PF07996 Type IV secretion system proteins 28 215 2.3E-38 T 26-04-2017 IPR014158 Type IV secretion system, VirB5 A4V04_RS06320 3e7d1ffaf09a4435bf83f6a108e9ef9e 247 Gene3D G3DSA:1.20.58.430 28 215 2.5E-40 T 26-04-2017 IPR023220 Type IV secretion system, VirB5-domain A4V04_RS01645 38050073885cf58780c6cf9dca05190a 339 SUPERFAMILY SSF53850 102 298 4.65E-19 T 26-04-2017 A4V04_RS01645 38050073885cf58780c6cf9dca05190a 339 Pfam PF03466 LysR substrate binding domain 101 285 5.4E-16 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS01645 38050073885cf58780c6cf9dca05190a 339 Gene3D G3DSA:1.10.10.10 15 94 2.3E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01645 38050073885cf58780c6cf9dca05190a 339 Gene3D G3DSA:3.40.190.10 183 252 1.8E-4 T 26-04-2017 A4V04_RS01645 38050073885cf58780c6cf9dca05190a 339 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 71 8.5E-15 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS01645 38050073885cf58780c6cf9dca05190a 339 SUPERFAMILY SSF46785 15 109 5.08E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01645 38050073885cf58780c6cf9dca05190a 339 Gene3D G3DSA:3.40.190.10 102 182 5.8E-5 T 26-04-2017 A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 Pfam PF11987 Translation-initiation factor 2 715 818 3.6E-37 T 26-04-2017 IPR023115 Translation initiation factor IF- 2, domain 3 A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 SUPERFAMILY SSF52540 425 598 9.14E-54 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 Pfam PF00009 Elongation factor Tu GTP binding domain 434 589 1.5E-35 T 26-04-2017 A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 SUPERFAMILY SSF50447 602 684 2.29E-25 T 26-04-2017 IPR009000 Translation protein, beta-barrel domain A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 Pfam PF03144 Elongation factor Tu domain 2 849 912 3.7E-8 T 26-04-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 Gene3D G3DSA:3.30.56.50 2 51 9.7E-11 T 26-04-2017 A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 Gene3D G3DSA:2.40.30.10 830 926 2.3E-35 T 26-04-2017 A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 SUPERFAMILY SSF46955 3 51 6.04E-5 T 26-04-2017 IPR009061 Putative DNA-binding domain A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 SUPERFAMILY SSF50447 830 926 3.14E-32 T 26-04-2017 IPR009000 Translation protein, beta-barrel domain A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 ProSitePatterns PS01176 Initiation factor 2 signature. 879 901 - T 26-04-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 Gene3D G3DSA:3.40.50.300 428 588 3.1E-48 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 SUPERFAMILY SSF52156 708 835 1.29E-36 T 26-04-2017 IPR023115 Translation initiation factor IF- 2, domain 3 A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 926 17.499 T 26-04-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 Gene3D G3DSA:3.40.50.10050 729 807 2.1E-25 T 26-04-2017 IPR023115 Translation initiation factor IF- 2, domain 3 A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 432 588 1.8E-32 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 346 928 1.8E-258 T 26-04-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 351 401 2.7E-15 T 26-04-2017 IPR006847 Translation initiation factor IF-2, N-terminal A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 Gene3D G3DSA:2.40.30.10 601 693 4.4E-24 T 26-04-2017 A4V04_RS02720 cd42289349e5cbf4eb9097a01cf2c42c 929 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 61 99 4.1E-10 T 26-04-2017 IPR013575 Initiation factor 2 associated domain, bacterial A4V04_RS11125 f3755c80a7396d6e813e50b3cc63371a 180 Pfam PF02357 Transcription termination factor nusG 5 109 5.3E-26 T 26-04-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4V04_RS11125 f3755c80a7396d6e813e50b3cc63371a 180 SMART SM00738 4 113 1.5E-41 T 26-04-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4V04_RS11125 f3755c80a7396d6e813e50b3cc63371a 180 PRINTS PR00338 Transcription termination factor NUSG signature 155 171 6.2E-15 T 26-04-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4V04_RS11125 f3755c80a7396d6e813e50b3cc63371a 180 PRINTS PR00338 Transcription termination factor NUSG signature 59 71 6.2E-15 T 26-04-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4V04_RS11125 f3755c80a7396d6e813e50b3cc63371a 180 PRINTS PR00338 Transcription termination factor NUSG signature 137 152 6.2E-15 T 26-04-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4V04_RS11125 f3755c80a7396d6e813e50b3cc63371a 180 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 4 179 23.926 T 26-04-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4V04_RS11125 f3755c80a7396d6e813e50b3cc63371a 180 SUPERFAMILY SSF82679 5 115 6.8E-37 T 26-04-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4V04_RS11125 f3755c80a7396d6e813e50b3cc63371a 180 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 7 179 6.2E-62 T 26-04-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4V04_RS11125 f3755c80a7396d6e813e50b3cc63371a 180 Gene3D G3DSA:3.30.70.940 5 115 1.0E-41 T 26-04-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4V04_RS11125 f3755c80a7396d6e813e50b3cc63371a 180 SMART SM00739 125 152 3.9E-5 T 26-04-2017 IPR005824 KOW A4V04_RS11125 f3755c80a7396d6e813e50b3cc63371a 180 SUPERFAMILY SSF50104 124 179 2.86E-18 T 26-04-2017 IPR008991 Translation protein SH3-like domain A4V04_RS11125 f3755c80a7396d6e813e50b3cc63371a 180 Gene3D G3DSA:2.30.30.30 118 179 1.1E-26 T 26-04-2017 IPR014722 Ribosomal protein L2 domain 2 A4V04_RS11125 f3755c80a7396d6e813e50b3cc63371a 180 Pfam PF00467 KOW motif 128 160 1.7E-5 T 26-04-2017 IPR005824 KOW A4V04_RS06930 661d3baceaeee68a1e34943f77c1b737 176 Pfam PF01985 CRS1 / YhbY (CRM) domain 6 89 2.9E-17 T 26-04-2017 IPR001890 RNA-binding, CRM domain GO:0003723 A4V04_RS06930 661d3baceaeee68a1e34943f77c1b737 176 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 12 98 2.7E-26 T 26-04-2017 IPR017924 RNA-binding protein YhbY GO:0003723 A4V04_RS06930 661d3baceaeee68a1e34943f77c1b737 176 SMART SM01103 6 89 8.7E-34 T 26-04-2017 IPR001890 RNA-binding, CRM domain GO:0003723 A4V04_RS06930 661d3baceaeee68a1e34943f77c1b737 176 SUPERFAMILY SSF75471 6 97 3.79E-27 T 26-04-2017 IPR001890 RNA-binding, CRM domain GO:0003723 A4V04_RS06930 661d3baceaeee68a1e34943f77c1b737 176 Gene3D G3DSA:3.30.110.60 5 99 1.8E-28 T 26-04-2017 IPR001890 RNA-binding, CRM domain GO:0003723 A4V04_RS06930 661d3baceaeee68a1e34943f77c1b737 176 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 15 90 3.0E-21 T 26-04-2017 IPR001890 RNA-binding, CRM domain GO:0003723 A4V04_RS04225 ec4f1e9fefef57bbf9907a84c6b083de 266 Gene3D G3DSA:3.40.190.10 29 159 7.7E-54 T 26-04-2017 A4V04_RS04225 ec4f1e9fefef57bbf9907a84c6b083de 266 Pfam PF03180 NLPA lipoprotein 31 265 4.9E-89 T 26-04-2017 IPR004872 Lipoprotein NlpA family A4V04_RS04225 ec4f1e9fefef57bbf9907a84c6b083de 266 SUPERFAMILY SSF53850 30 266 3.67E-81 T 26-04-2017 A4V04_RS04225 ec4f1e9fefef57bbf9907a84c6b083de 266 PIRSF PIRSF002854 1 266 3.4E-97 T 26-04-2017 IPR004872 Lipoprotein NlpA family A4V04_RS12735 43c8045396976b7340eb2d7a6be60848 154 Gene3D G3DSA:3.10.129.10 1 129 2.9E-28 T 26-04-2017 IPR029069 HotDog domain A4V04_RS12735 43c8045396976b7340eb2d7a6be60848 154 Pfam PF13279 Thioesterase-like superfamily 11 128 4.7E-12 T 26-04-2017 A4V04_RS12735 43c8045396976b7340eb2d7a6be60848 154 SUPERFAMILY SSF54637 1 131 8.92E-34 T 26-04-2017 IPR029069 HotDog domain A4V04_RS12730 48197620d79cfee7a087511c34070f73 505 Gene3D G3DSA:3.50.50.60 25 262 1.4E-66 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12730 48197620d79cfee7a087511c34070f73 505 Gene3D G3DSA:3.50.50.60 439 503 1.4E-66 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12730 48197620d79cfee7a087511c34070f73 505 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 459 474 1.3E-7 T 26-04-2017 A4V04_RS12730 48197620d79cfee7a087511c34070f73 505 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 31 53 1.3E-7 T 26-04-2017 A4V04_RS12730 48197620d79cfee7a087511c34070f73 505 Pfam PF00890 FAD binding domain 31 478 5.1E-49 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS12730 48197620d79cfee7a087511c34070f73 505 SUPERFAMILY SSF56425 287 443 1.05E-19 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS12730 48197620d79cfee7a087511c34070f73 505 SUPERFAMILY SSF51905 442 504 1.94E-46 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12730 48197620d79cfee7a087511c34070f73 505 SUPERFAMILY SSF51905 24 272 1.94E-46 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12730 48197620d79cfee7a087511c34070f73 505 Gene3D G3DSA:3.90.700.10 288 432 3.4E-22 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02585 7039da13bada84556b9c4b94b79e1242 87 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 3 84 1.5E-20 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS02585 7039da13bada84556b9c4b94b79e1242 87 Pfam PF04221 RelB antitoxin 8 84 1.9E-16 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS02585 7039da13bada84556b9c4b94b79e1242 87 PIRSF PIRSF003108 1 87 3.7E-19 T 26-04-2017 IPR026262 Antitoxin DinJ GO:0000986|GO:0015643|GO:0044010 A4V04_RS06395 7039da13bada84556b9c4b94b79e1242 87 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 3 84 1.5E-20 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS06395 7039da13bada84556b9c4b94b79e1242 87 Pfam PF04221 RelB antitoxin 8 84 1.9E-16 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS06395 7039da13bada84556b9c4b94b79e1242 87 PIRSF PIRSF003108 1 87 3.7E-19 T 26-04-2017 IPR026262 Antitoxin DinJ GO:0000986|GO:0015643|GO:0044010 A4V04_RS11140 3fa4b4de00e89c4341c5169ccd0a20f7 175 SUPERFAMILY SSF160369 4 169 3.4E-53 T 26-04-2017 A4V04_RS11140 3fa4b4de00e89c4341c5169ccd0a20f7 175 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 153 0.001 T 26-04-2017 A4V04_RS11140 3fa4b4de00e89c4341c5169ccd0a20f7 175 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 160 26.271 T 26-04-2017 IPR022973 Ribosomal protein L10 A4V04_RS11140 3fa4b4de00e89c4341c5169ccd0a20f7 175 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 26-04-2017 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11140 3fa4b4de00e89c4341c5169ccd0a20f7 175 Pfam PF00466 Ribosomal protein L10 4 100 9.4E-24 T 26-04-2017 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 A4V04_RS05645 de805955209edf347b79d844a9750c05 265 SUPERFAMILY SSF56219 4 265 3.14E-73 T 26-04-2017 IPR005135 Endonuclease/exonuclease/phosphatase A4V04_RS05645 de805955209edf347b79d844a9750c05 265 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 4 263 5.2E-75 T 26-04-2017 A4V04_RS05645 de805955209edf347b79d844a9750c05 265 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 4 263 1.1E-69 T 26-04-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 A4V04_RS05645 de805955209edf347b79d844a9750c05 265 Gene3D G3DSA:3.60.10.10 4 264 8.5E-76 T 26-04-2017 IPR005135 Endonuclease/exonuclease/phosphatase A4V04_RS05645 de805955209edf347b79d844a9750c05 265 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 195 210 - T 26-04-2017 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 A4V04_RS05645 de805955209edf347b79d844a9750c05 265 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 220 231 - T 26-04-2017 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 A4V04_RS05645 de805955209edf347b79d844a9750c05 265 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 256 1.6E-23 T 26-04-2017 IPR005135 Endonuclease/exonuclease/phosphatase A4V04_RS05645 de805955209edf347b79d844a9750c05 265 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 26-04-2017 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 A4V04_RS03490 38ff32387d265d3e929615b473e3db14 257 Gene3D G3DSA:3.30.70.580 2 104 8.0E-35 T 26-04-2017 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS03490 38ff32387d265d3e929615b473e3db14 257 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 243 34.237 T 26-04-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS03490 38ff32387d265d3e929615b473e3db14 257 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 238 5.1E-65 T 26-04-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS03490 38ff32387d265d3e929615b473e3db14 257 PIRSF PIRSF001430 1 255 1.4E-77 T 26-04-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS03490 38ff32387d265d3e929615b473e3db14 257 Gene3D G3DSA:3.30.70.660 106 241 5.7E-46 T 26-04-2017 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS03490 38ff32387d265d3e929615b473e3db14 257 SUPERFAMILY SSF55120 1 251 3.45E-88 T 26-04-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS03490 38ff32387d265d3e929615b473e3db14 257 Pfam PF01416 tRNA pseudouridine synthase 143 244 2.4E-28 T 26-04-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS03490 38ff32387d265d3e929615b473e3db14 257 Pfam PF01416 tRNA pseudouridine synthase 9 103 1.0E-7 T 26-04-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS09380 aa8706c036a4acd88865238b84ea2997 296 SUPERFAMILY SSF53850 89 291 1.48E-33 T 26-04-2017 A4V04_RS09380 aa8706c036a4acd88865238b84ea2997 296 Gene3D G3DSA:1.10.10.10 4 86 9.5E-23 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09380 aa8706c036a4acd88865238b84ea2997 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.2E-5 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09380 aa8706c036a4acd88865238b84ea2997 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.2E-5 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09380 aa8706c036a4acd88865238b84ea2997 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.2E-5 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09380 aa8706c036a4acd88865238b84ea2997 296 Gene3D G3DSA:3.40.190.10 175 260 4.5E-14 T 26-04-2017 A4V04_RS09380 aa8706c036a4acd88865238b84ea2997 296 Gene3D G3DSA:3.40.190.10 92 174 1.3E-17 T 26-04-2017 A4V04_RS09380 aa8706c036a4acd88865238b84ea2997 296 SUPERFAMILY SSF46785 4 88 5.72E-20 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09380 aa8706c036a4acd88865238b84ea2997 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.4E-17 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09380 aa8706c036a4acd88865238b84ea2997 296 Pfam PF03466 LysR substrate binding domain 88 289 2.6E-33 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS11410 573385930d85a482997e944fcb2d49b7 197 Gene3D G3DSA:3.30.70.20 1 63 1.2E-15 T 26-04-2017 A4V04_RS11410 573385930d85a482997e944fcb2d49b7 197 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 91 102 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS11410 573385930d85a482997e944fcb2d49b7 197 Pfam PF12800 4Fe-4S binding domain 11 24 0.053 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS11410 573385930d85a482997e944fcb2d49b7 197 Gene3D G3DSA:3.30.70.20 65 109 1.3E-26 T 26-04-2017 A4V04_RS11410 573385930d85a482997e944fcb2d49b7 197 Gene3D G3DSA:3.30.70.20 110 185 2.1E-22 T 26-04-2017 A4V04_RS11410 573385930d85a482997e944fcb2d49b7 197 SUPERFAMILY SSF54862 1 181 3.45E-66 T 26-04-2017 A4V04_RS11410 573385930d85a482997e944fcb2d49b7 197 Pfam PF13247 4Fe-4S dicluster domain 52 146 8.2E-24 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 13 947 20.264 T 26-04-2017 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 Gene3D G3DSA:3.90.740.10 215 405 1.6E-52 T 26-04-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 SUPERFAMILY SSF47323 684 946 5.23E-66 T 26-04-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 40 672 4.0E-214 T 26-04-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 SUPERFAMILY SSF50677 212 419 3.27E-48 T 26-04-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 593 602 5.2E-31 T 26-04-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 557 570 5.2E-31 T 26-04-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 247 270 5.2E-31 T 26-04-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 62 73 5.2E-31 T 26-04-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 417 432 5.2E-31 T 26-04-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 25 872 4.1E-266 T 26-04-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 Gene3D G3DSA:3.40.50.620 419 669 7.6E-134 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 Gene3D G3DSA:3.40.50.620 28 213 7.6E-134 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 Pfam PF08264 Anticodon-binding domain of tRNA 717 871 2.3E-23 T 26-04-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 SUPERFAMILY SSF52374 419 681 2.07E-132 T 26-04-2017 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 SUPERFAMILY SSF52374 19 210 2.07E-132 T 26-04-2017 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 Pfam PF06827 Zinc finger found in FPG and IleRS 917 943 2.1E-4 T 26-04-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 69 80 - T 26-04-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS00825 f6ef815b73eefcce73c80ea77708185f 956 Gene3D G3DSA:1.10.730.10 675 820 7.2E-39 T 26-04-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS11065 90aa86e82a9675e509ee6108740f4c7c 183 Pfam PF05036 Sporulation related domain 109 177 9.2E-19 T 26-04-2017 IPR007730 Sporulation-related domain GO:0042834 A4V04_RS11065 90aa86e82a9675e509ee6108740f4c7c 183 SUPERFAMILY SSF110997 107 179 5.89E-18 T 26-04-2017 IPR007730 Sporulation-related domain GO:0042834 A4V04_RS11065 90aa86e82a9675e509ee6108740f4c7c 183 Gene3D G3DSA:3.30.70.1070 103 179 4.3E-22 T 26-04-2017 IPR007730 Sporulation-related domain GO:0042834 A4V04_RS11475 3039615ea374a39dd184499b51be0cdc 383 Pfam PF13173 AAA domain 18 139 1.3E-25 T 26-04-2017 A4V04_RS11475 3039615ea374a39dd184499b51be0cdc 383 SUPERFAMILY SSF52540 7 153 1.65E-18 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11475 3039615ea374a39dd184499b51be0cdc 383 Gene3D G3DSA:3.40.50.300 7 111 1.5E-8 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11475 3039615ea374a39dd184499b51be0cdc 383 Pfam PF13635 Domain of unknown function (DUF4143) 189 343 2.1E-18 T 26-04-2017 IPR025420 Domain of unknown function DUF4143 A4V04_RS05760 b15b9699fae8322eb6ec615e55089eaf 297 SUPERFAMILY SSF52317 7 155 8.24E-27 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS05760 b15b9699fae8322eb6ec615e55089eaf 297 Gene3D G3DSA:3.50.30.60 162 288 3.6E-39 T 26-04-2017 IPR027461 LD-carboxypeptidase A, C-terminal domain A4V04_RS05760 b15b9699fae8322eb6ec615e55089eaf 297 PIRSF PIRSF028757 1 295 1.7E-67 T 26-04-2017 IPR003507 Peptidase family S66 A4V04_RS05760 b15b9699fae8322eb6ec615e55089eaf 297 SUPERFAMILY SSF141986 133 285 6.28E-39 T 26-04-2017 IPR027461 LD-carboxypeptidase A, C-terminal domain A4V04_RS05760 b15b9699fae8322eb6ec615e55089eaf 297 Pfam PF02016 LD-carboxypeptidase 7 279 1.1E-65 T 26-04-2017 IPR003507 Peptidase family S66 A4V04_RS05760 b15b9699fae8322eb6ec615e55089eaf 297 Gene3D G3DSA:3.40.50.10740 7 154 2.4E-31 T 26-04-2017 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain A4V04_RS03605 b4c4aab32df715c40e4b237db6128cc7 308 Pfam PF01012 Electron transfer flavoprotein domain 3 168 4.5E-35 T 26-04-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4V04_RS03605 b4c4aab32df715c40e4b237db6128cc7 308 SUPERFAMILY SSF52467 186 307 1.07E-43 T 26-04-2017 IPR029035 DHS-like NAD/FAD-binding domain A4V04_RS03605 b4c4aab32df715c40e4b237db6128cc7 308 SUPERFAMILY SSF52402 3 182 4.1E-46 T 26-04-2017 A4V04_RS03605 b4c4aab32df715c40e4b237db6128cc7 308 PIRSF PIRSF000089 1 308 1.1E-92 T 26-04-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 A4V04_RS03605 b4c4aab32df715c40e4b237db6128cc7 308 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 189 271 4.2E-33 T 26-04-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 A4V04_RS03605 b4c4aab32df715c40e4b237db6128cc7 308 SMART SM00893 3 181 6.2E-37 T 26-04-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4V04_RS03605 b4c4aab32df715c40e4b237db6128cc7 308 Gene3D G3DSA:3.40.50.1220 182 308 8.5E-55 T 26-04-2017 IPR029035 DHS-like NAD/FAD-binding domain A4V04_RS03605 b4c4aab32df715c40e4b237db6128cc7 308 Gene3D G3DSA:3.40.50.620 1 180 3.7E-49 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS03945 65dfd114b6b0bfff75ceff2321e8caaa 307 Pfam PF02601 Exonuclease VII, large subunit 177 237 1.2E-9 T 26-04-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 A4V04_RS12115 964c97e185ac9e47f2ace332116257da 322 SUPERFAMILY SSF46785 3 86 1.36E-16 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS12115 964c97e185ac9e47f2ace332116257da 322 Gene3D G3DSA:3.40.190.10 92 159 2.8E-4 T 26-04-2017 A4V04_RS12115 964c97e185ac9e47f2ace332116257da 322 Gene3D G3DSA:3.40.190.10 165 264 3.3E-17 T 26-04-2017 A4V04_RS12115 964c97e185ac9e47f2ace332116257da 322 SUPERFAMILY SSF53850 92 299 4.34E-31 T 26-04-2017 A4V04_RS12115 964c97e185ac9e47f2ace332116257da 322 Gene3D G3DSA:1.10.10.10 6 89 4.6E-18 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS12115 964c97e185ac9e47f2ace332116257da 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 8.1E-14 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS12115 964c97e185ac9e47f2ace332116257da 322 Pfam PF03466 LysR substrate binding domain 91 296 1.7E-25 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS04845 1b412f9bb2345c5aea47b2eed16ddc9f 519 Gene3D G3DSA:3.30.420.40 259 495 3.4E-33 T 26-04-2017 A4V04_RS04845 1b412f9bb2345c5aea47b2eed16ddc9f 519 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 269 456 1.9E-15 T 26-04-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A4V04_RS04845 1b412f9bb2345c5aea47b2eed16ddc9f 519 SUPERFAMILY SSF53067 258 497 1.62E-37 T 26-04-2017 A4V04_RS04845 1b412f9bb2345c5aea47b2eed16ddc9f 519 Gene3D G3DSA:3.30.420.40 2 256 4.3E-46 T 26-04-2017 A4V04_RS04845 1b412f9bb2345c5aea47b2eed16ddc9f 519 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 256 5.7E-35 T 26-04-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A4V04_RS04845 1b412f9bb2345c5aea47b2eed16ddc9f 519 SUPERFAMILY SSF53067 4 258 2.19E-43 T 26-04-2017 A4V04_RS04845 1b412f9bb2345c5aea47b2eed16ddc9f 519 PIRSF PIRSF000538 2 505 4.9E-85 T 26-04-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 SUPERFAMILY SSF46548 344 469 3.14E-25 T 26-04-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 Gene3D G3DSA:1.10.1060.10 321 461 3.5E-32 T 26-04-2017 A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 SUPERFAMILY SSF54862 86 107 6.7E-15 T 26-04-2017 A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 SUPERFAMILY SSF54862 179 310 6.7E-15 T 26-04-2017 A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 Pfam PF12801 4Fe-4S binding domain 211 252 0.01 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 Pfam PF12801 4Fe-4S binding domain 76 108 8.8E-9 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 Pfam PF12801 4Fe-4S binding domain 59 66 600.0 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 Pfam PF12801 4Fe-4S binding domain 168 193 700.0 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 Gene3D G3DSA:3.50.50.60 647 750 1.6E-8 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 460 738 1.0E-17 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 SUPERFAMILY SSF51971 459 692 1.82E-45 T 26-04-2017 A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 Pfam PF00037 4Fe-4S binding domain 291 308 3.2E-6 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 293 304 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 PRINTS PR00419 Adrenodoxin reductase family signature 598 612 9.7E-20 T 26-04-2017 A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 PRINTS PR00419 Adrenodoxin reductase family signature 460 482 9.7E-20 T 26-04-2017 A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 PRINTS PR00419 Adrenodoxin reductase family signature 483 496 9.7E-20 T 26-04-2017 A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 344 435 1.3E-25 T 26-04-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 Gene3D G3DSA:3.50.50.60 462 646 4.2E-44 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 359 370 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS07515 60e371d6e6a11db1040b5408f2e66eda 756 Gene3D G3DSA:3.30.70.20 267 310 1.1E-8 T 26-04-2017 A4V04_RS05860 717ae2c00e05902803a92c214bd2c67a 166 Gene3D G3DSA:3.30.910.20 16 62 2.2E-36 T 26-04-2017 A4V04_RS05860 717ae2c00e05902803a92c214bd2c67a 166 Gene3D G3DSA:3.30.910.20 100 166 2.2E-36 T 26-04-2017 A4V04_RS05860 717ae2c00e05902803a92c214bd2c67a 166 SMART SM00935 14 166 1.4E-55 T 26-04-2017 IPR005632 Chaperone protein Skp GO:0051082 A4V04_RS05860 717ae2c00e05902803a92c214bd2c67a 166 Pfam PF03938 Outer membrane protein (OmpH-like) 14 165 1.2E-36 T 26-04-2017 IPR005632 Chaperone protein Skp GO:0051082 A4V04_RS05860 717ae2c00e05902803a92c214bd2c67a 166 SUPERFAMILY SSF111384 24 166 5.49E-35 T 26-04-2017 IPR024930 Skp domain A4V04_RS05860 717ae2c00e05902803a92c214bd2c67a 166 PIRSF PIRSF002094 1 166 3.5E-50 T 26-04-2017 IPR005632 Chaperone protein Skp GO:0051082 A4V04_RS03730 172ef92b6dd875c9b8bedcd484e57cb3 105 SMART SM00411 1 90 1.3E-36 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS03730 172ef92b6dd875c9b8bedcd484e57cb3 105 Pfam PF00216 Bacterial DNA-binding protein 1 90 5.0E-30 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS03730 172ef92b6dd875c9b8bedcd484e57cb3 105 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 26-04-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A4V04_RS03730 172ef92b6dd875c9b8bedcd484e57cb3 105 Gene3D G3DSA:4.10.520.10 1 91 4.5E-33 T 26-04-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4V04_RS03730 172ef92b6dd875c9b8bedcd484e57cb3 105 SUPERFAMILY SSF47729 1 90 2.8E-30 T 26-04-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4V04_RS03730 172ef92b6dd875c9b8bedcd484e57cb3 105 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.0E-12 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS03730 172ef92b6dd875c9b8bedcd484e57cb3 105 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.0E-12 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS03730 172ef92b6dd875c9b8bedcd484e57cb3 105 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.0E-12 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS08630 9dd2e8857c9872b89e0711dfaf285e4c 794 Pfam PF04453 Organic solvent tolerance protein 308 699 1.8E-74 T 26-04-2017 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 A4V04_RS08630 9dd2e8857c9872b89e0711dfaf285e4c 794 Pfam PF03968 OstA-like protein 80 203 3.2E-4 T 26-04-2017 IPR005653 Organic solvent tolerance-like, N-terminal A4V04_RS08630 9dd2e8857c9872b89e0711dfaf285e4c 794 Gene3D G3DSA:2.60.450.10 66 210 2.2E-8 T 26-04-2017 A4V04_RS08630 9dd2e8857c9872b89e0711dfaf285e4c 794 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 11 761 19.219 T 26-04-2017 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 A4V04_RS07335 cb8bd9363336ecbd53873264d2e95864 442 Pfam PF07282 Putative transposase DNA-binding domain 313 391 6.2E-9 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS07335 cb8bd9363336ecbd53873264d2e95864 442 Pfam PF01385 Probable transposase 191 292 2.3E-13 T 26-04-2017 IPR001959 Probable transposase, IS891/IS1136/IS1341 A4V04_RS07335 cb8bd9363336ecbd53873264d2e95864 442 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 260 340 1.9E-18 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS08985 6924ce2a15d6946000e8e24e1e10feaf 163 SUPERFAMILY SSF54637 17 138 6.71E-35 T 26-04-2017 IPR029069 HotDog domain A4V04_RS08985 6924ce2a15d6946000e8e24e1e10feaf 163 Gene3D G3DSA:3.10.129.10 9 138 3.4E-37 T 26-04-2017 IPR029069 HotDog domain A4V04_RS08985 6924ce2a15d6946000e8e24e1e10feaf 163 Pfam PF03061 Thioesterase superfamily 34 105 9.5E-16 T 26-04-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 A4V04_RS02965 7869948312a29345017d8aeb77a4b71b 211 Pfam PF03466 LysR substrate binding domain 4 185 4.3E-14 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS02965 7869948312a29345017d8aeb77a4b71b 211 Gene3D G3DSA:3.40.190.10 2 97 2.5E-5 T 26-04-2017 A4V04_RS02965 7869948312a29345017d8aeb77a4b71b 211 SUPERFAMILY SSF53850 2 194 1.07E-17 T 26-04-2017 A4V04_RS02965 7869948312a29345017d8aeb77a4b71b 211 Gene3D G3DSA:3.40.190.10 98 154 6.5E-5 T 26-04-2017 A4V04_RS10555 626f6b9bbe417c5d889288ccd260ff63 397 Pfam PF07690 Major Facilitator Superfamily 21 358 9.4E-17 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS10555 626f6b9bbe417c5d889288ccd260ff63 397 Gene3D G3DSA:1.20.1250.20 15 181 1.4E-10 T 26-04-2017 A4V04_RS10555 626f6b9bbe417c5d889288ccd260ff63 397 Gene3D G3DSA:1.20.1250.20 213 388 9.0E-11 T 26-04-2017 A4V04_RS10555 626f6b9bbe417c5d889288ccd260ff63 397 SUPERFAMILY SSF103473 3 389 2.09E-34 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS04000 e99aec76e9d3b0c996c4573d3c3e6cc4 204 Gene3D G3DSA:3.30.70.20 119 172 1.4E-16 T 26-04-2017 A4V04_RS04000 e99aec76e9d3b0c996c4573d3c3e6cc4 204 Pfam PF13247 4Fe-4S dicluster domain 60 156 6.2E-27 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS04000 e99aec76e9d3b0c996c4573d3c3e6cc4 204 SUPERFAMILY SSF54862 1 186 8.06E-63 T 26-04-2017 A4V04_RS04000 e99aec76e9d3b0c996c4573d3c3e6cc4 204 Gene3D G3DSA:3.30.70.20 78 118 2.8E-23 T 26-04-2017 A4V04_RS04000 e99aec76e9d3b0c996c4573d3c3e6cc4 204 TIGRFAM TIGR02951 DMSO_dmsB: dimethylsulfoxide reductase, chain B 3 165 4.9E-67 T 26-04-2017 IPR014297 Dimethylsulphoxide reductase, chain B A4V04_RS04000 e99aec76e9d3b0c996c4573d3c3e6cc4 204 Gene3D G3DSA:3.30.70.20 3 77 1.9E-17 T 26-04-2017 A4V04_RS04000 e99aec76e9d3b0c996c4573d3c3e6cc4 204 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS04000 e99aec76e9d3b0c996c4573d3c3e6cc4 204 Pfam PF12800 4Fe-4S binding domain 11 23 0.011 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS08180 d8fd7921b5e43dd0d9ebce0c5b5cdf52 480 SUPERFAMILY SSF111283 22 479 1.27E-124 T 26-04-2017 A4V04_RS08180 d8fd7921b5e43dd0d9ebce0c5b5cdf52 480 Pfam PF01523 Putative modulator of DNA gyrase 38 331 2.8E-63 T 26-04-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A4V04_RS08180 d8fd7921b5e43dd0d9ebce0c5b5cdf52 480 PIRSF PIRSF004919 18 480 1.1E-130 T 26-04-2017 IPR025502 TldD A4V04_RS09775 7559cb8e0cdd431f9e7c6658dbe1cc25 473 Gene3D G3DSA:3.40.630.10 2 202 1.1E-45 T 26-04-2017 A4V04_RS09775 7559cb8e0cdd431f9e7c6658dbe1cc25 473 Gene3D G3DSA:3.40.630.10 381 470 1.1E-45 T 26-04-2017 A4V04_RS09775 7559cb8e0cdd431f9e7c6658dbe1cc25 473 Gene3D G3DSA:3.30.70.360 208 374 1.9E-20 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS09775 7559cb8e0cdd431f9e7c6658dbe1cc25 473 SUPERFAMILY SSF53187 5 208 2.54E-44 T 26-04-2017 A4V04_RS09775 7559cb8e0cdd431f9e7c6658dbe1cc25 473 SUPERFAMILY SSF53187 382 470 2.54E-44 T 26-04-2017 A4V04_RS09775 7559cb8e0cdd431f9e7c6658dbe1cc25 473 Pfam PF07687 Peptidase dimerisation domain 206 365 3.5E-7 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS09775 7559cb8e0cdd431f9e7c6658dbe1cc25 473 Pfam PF01546 Peptidase family M20/M25/M40 95 466 2.5E-21 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS05370 c039928a5d1e4724d6385b558a9f0642 214 Pfam PF00881 Nitroreductase family 8 189 1.4E-20 T 26-04-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4V04_RS05370 c039928a5d1e4724d6385b558a9f0642 214 Gene3D G3DSA:3.40.109.10 1 210 1.4E-56 T 26-04-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4V04_RS05370 c039928a5d1e4724d6385b558a9f0642 214 SUPERFAMILY SSF55469 1 212 1.1E-53 T 26-04-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4V04_RS11060 1053c63e0c0520e95a4e4ba1c470c994 211 Gene3D G3DSA:3.40.30.10 28 209 7.7E-48 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS11060 1053c63e0c0520e95a4e4ba1c470c994 211 PIRSF PIRSF001488 2 210 1.3E-44 T 26-04-2017 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL A4V04_RS11060 1053c63e0c0520e95a4e4ba1c470c994 211 ProSitePatterns PS00194 Thioredoxin family active site. 49 67 - T 26-04-2017 IPR017937 Thioredoxin, conserved site GO:0045454 A4V04_RS11060 1053c63e0c0520e95a4e4ba1c470c994 211 Pfam PF13462 Thioredoxin 46 192 5.1E-9 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS11060 1053c63e0c0520e95a4e4ba1c470c994 211 SUPERFAMILY SSF52833 27 191 1.72E-36 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS09375 8a1a6b4ffce08552cf72c66fc2824e9d 374 Pfam PF01168 Alanine racemase, N-terminal domain 14 238 4.4E-25 T 26-04-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4V04_RS09375 8a1a6b4ffce08552cf72c66fc2824e9d 374 Gene3D G3DSA:3.20.20.10 25 236 9.1E-13 T 26-04-2017 IPR029066 PLP-binding barrel A4V04_RS09375 8a1a6b4ffce08552cf72c66fc2824e9d 374 SUPERFAMILY SSF51419 14 245 6.71E-27 T 26-04-2017 IPR029066 PLP-binding barrel A4V04_RS09375 8a1a6b4ffce08552cf72c66fc2824e9d 374 Pfam PF14031 Putative serine dehydratase domain 253 359 3.1E-17 T 26-04-2017 IPR026956 D-serine dehydratase-like domain A4V04_RS09375 8a1a6b4ffce08552cf72c66fc2824e9d 374 SMART SM01119 253 360 1.4E-36 T 26-04-2017 IPR026956 D-serine dehydratase-like domain A4V04_RS03555 3b4f56e5fb5506c4ef8b7a2c676a1e63 195 Pfam PF11159 Protein of unknown function (DUF2939) 19 108 1.2E-24 T 26-04-2017 IPR021330 Protein of unknown function DUF2939 A4V04_RS03650 2020a739c437220a19c258f77adf0cee 420 Gene3D G3DSA:3.30.2010.10 200 292 1.4E-19 T 26-04-2017 A4V04_RS03650 2020a739c437220a19c258f77adf0cee 420 Pfam PF01435 Peptidase family M48 207 414 4.2E-41 T 26-04-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4V04_RS03650 2020a739c437220a19c258f77adf0cee 420 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 30 203 3.9E-48 T 26-04-2017 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 A4V04_RS03060 36114d19470c3e46407999beffe1953d 353 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 338 353 5.8E-5 T 26-04-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A4V04_RS03060 36114d19470c3e46407999beffe1953d 353 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 82 102 5.8E-5 T 26-04-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A4V04_RS03060 36114d19470c3e46407999beffe1953d 353 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 68 347 3.2E-14 T 26-04-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A4V04_RS03060 36114d19470c3e46407999beffe1953d 353 Gene3D G3DSA:2.40.50.100 231 263 1.1E-12 T 26-04-2017 A4V04_RS03060 36114d19470c3e46407999beffe1953d 353 Gene3D G3DSA:2.40.50.100 71 104 1.1E-12 T 26-04-2017 A4V04_RS03060 36114d19470c3e46407999beffe1953d 353 SUPERFAMILY SSF111369 69 144 1.7E-7 T 26-04-2017 A4V04_RS03060 36114d19470c3e46407999beffe1953d 353 SUPERFAMILY SSF111369 218 282 2.62E-5 T 26-04-2017 A4V04_RS03060 36114d19470c3e46407999beffe1953d 353 SUPERFAMILY SSF111369 138 176 2.62E-5 T 26-04-2017 A4V04_RS03700 b6a8f78ede1ff2734499c14e422daacb 467 Gene3D G3DSA:3.90.700.10 263 400 4.2E-40 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03700 b6a8f78ede1ff2734499c14e422daacb 467 SUPERFAMILY SSF56425 260 403 2.09E-41 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03700 b6a8f78ede1ff2734499c14e422daacb 467 Pfam PF00890 FAD binding domain 24 448 3.9E-87 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03700 b6a8f78ede1ff2734499c14e422daacb 467 Gene3D G3DSA:3.50.50.60 404 466 1.2E-93 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03700 b6a8f78ede1ff2734499c14e422daacb 467 Gene3D G3DSA:3.50.50.60 20 257 1.2E-93 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03700 b6a8f78ede1ff2734499c14e422daacb 467 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 24 460 2.2E-134 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS03700 b6a8f78ede1ff2734499c14e422daacb 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 25 44 1.2E-7 T 26-04-2017 A4V04_RS03700 b6a8f78ede1ff2734499c14e422daacb 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 412 434 1.2E-7 T 26-04-2017 A4V04_RS03700 b6a8f78ede1ff2734499c14e422daacb 467 SUPERFAMILY SSF51905 407 466 1.04E-62 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03700 b6a8f78ede1ff2734499c14e422daacb 467 SUPERFAMILY SSF51905 16 280 1.04E-62 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:3.30.1490.20 1128 1151 4.2E-4 T 26-04-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:3.30.1490.20 200 235 5.1E-4 T 26-04-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:3.30.1490.20 1198 1240 4.2E-4 T 26-04-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:3.30.1490.20 145 163 5.1E-4 T 26-04-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 SUPERFAMILY SSF52540 1531 1827 2.99E-38 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 ProSitePatterns PS00211 ABC transporters family signature. 857 871 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 SUPERFAMILY SSF52540 644 942 6.47E-39 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 ProSitePatterns PS00211 ABC transporters family signature. 1390 1404 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:1.10.8.280 287 396 3.4E-20 T 26-04-2017 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 ProSitePatterns PS00211 ABC transporters family signature. 1735 1749 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:1.20.1580.10 1245 1380 1.2E-48 T 26-04-2017 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:1.20.1580.10 1092 1127 1.2E-48 T 26-04-2017 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:1.20.1580.10 397 414 1.2E-43 T 26-04-2017 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:1.20.1580.10 450 502 1.2E-43 T 26-04-2017 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:1.20.1580.10 98 135 1.2E-43 T 26-04-2017 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:1.20.1580.10 252 285 1.2E-43 T 26-04-2017 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 SUPERFAMILY SSF52540 1003 1202 5.06E-41 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 SUPERFAMILY SSF52540 1332 1472 5.06E-41 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 SUPERFAMILY SSF52540 455 594 1.89E-33 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 SUPERFAMILY SSF52540 10 160 1.89E-33 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 SMART SM00382 1536 1820 0.8 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 SMART SM00382 656 963 1.1 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 SMART SM00382 1021 1467 16.0 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 10 955 6.0E-282 T 26-04-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:1.20.1580.10 717 847 6.3E-41 T 26-04-2017 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:1.20.1580.10 1599 1725 5.0E-49 T 26-04-2017 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Pfam PF00005 ABC transporter 647 892 3.0E-7 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:3.40.50.300 503 620 1.0E-48 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:3.40.50.300 848 964 2.1E-47 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:3.40.50.300 641 715 2.1E-47 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:3.40.50.300 1381 1503 5.0E-56 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:3.40.50.300 1726 1849 1.0E-48 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:3.40.50.300 1511 1579 1.0E-48 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:3.40.50.300 8 57 1.0E-48 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08315 00fb678f3d0d9d70017377334935e62d 1855 Gene3D G3DSA:3.40.50.300 995 1056 5.0E-56 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07535 f7edd49fbd4e3e638300169422baa396 197 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 91 102 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS07535 f7edd49fbd4e3e638300169422baa396 197 Gene3D G3DSA:3.30.70.20 110 184 1.1E-20 T 26-04-2017 A4V04_RS07535 f7edd49fbd4e3e638300169422baa396 197 Pfam PF13247 4Fe-4S dicluster domain 52 146 8.6E-23 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07535 f7edd49fbd4e3e638300169422baa396 197 Pfam PF00037 4Fe-4S binding domain 7 23 4.1E-5 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07535 f7edd49fbd4e3e638300169422baa396 197 SUPERFAMILY SSF54862 1 181 5.55E-63 T 26-04-2017 A4V04_RS07535 f7edd49fbd4e3e638300169422baa396 197 Gene3D G3DSA:3.30.70.20 65 109 4.9E-26 T 26-04-2017 A4V04_RS07535 f7edd49fbd4e3e638300169422baa396 197 Gene3D G3DSA:3.30.70.20 1 63 2.7E-15 T 26-04-2017 A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 Pfam PF00206 Lyase 8 302 3.5E-58 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 Gene3D G3DSA:1.10.275.10 3 108 2.7E-39 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 Gene3D G3DSA:1.10.40.30 376 432 2.2E-29 T 26-04-2017 A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 4.1E-18 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 4.1E-18 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 PRINTS PR00149 Fumarate lyase superfamily signature 233 260 4.1E-18 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 4.1E-18 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 Hamap MF_00006 Argininosuccinate lyase [argH]. 4 455 39.852 T 26-04-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 Gene3D G3DSA:1.20.200.10 109 375 2.3E-85 T 26-04-2017 A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 TIGRFAM TIGR00838 argH: argininosuccinate lyase 5 457 1.4E-175 T 26-04-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 1.9E-54 T 26-04-2017 A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 PRINTS PR00145 Argininosuccinate lyase family signature 233 257 1.9E-54 T 26-04-2017 A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 PRINTS PR00145 Argininosuccinate lyase family signature 144 164 1.9E-54 T 26-04-2017 A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 PRINTS PR00145 Argininosuccinate lyase family signature 195 211 1.9E-54 T 26-04-2017 A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 PRINTS PR00145 Argininosuccinate lyase family signature 103 125 1.9E-54 T 26-04-2017 A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 PRINTS PR00145 Argininosuccinate lyase family signature 312 331 1.9E-54 T 26-04-2017 A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 SUPERFAMILY SSF48557 5 457 3.3E-134 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS02440 b89d94fb24e59e5181dac8aaddb556c5 465 Pfam PF14698 Argininosuccinate lyase C-terminal 365 432 2.6E-24 T 26-04-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS01080 cd36345d647708d6026c671ec8eb0342 264 PIRSF PIRSF000513 10 264 6.9E-85 T 26-04-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS01080 cd36345d647708d6026c671ec8eb0342 264 SUPERFAMILY SSF53613 9 262 1.45E-61 T 26-04-2017 IPR029056 Ribokinase-like A4V04_RS01080 cd36345d647708d6026c671ec8eb0342 264 Pfam PF02110 Hydroxyethylthiazole kinase family 16 260 4.5E-80 T 26-04-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS01080 cd36345d647708d6026c671ec8eb0342 264 Gene3D G3DSA:3.40.1190.20 8 262 9.5E-86 T 26-04-2017 IPR029056 Ribokinase-like A4V04_RS01080 cd36345d647708d6026c671ec8eb0342 264 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 16 261 8.6E-81 T 26-04-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS01080 cd36345d647708d6026c671ec8eb0342 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 168 185 1.0E-34 T 26-04-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS01080 cd36345d647708d6026c671ec8eb0342 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 37 58 1.0E-34 T 26-04-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS01080 cd36345d647708d6026c671ec8eb0342 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 94 111 1.0E-34 T 26-04-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS01080 cd36345d647708d6026c671ec8eb0342 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 124 138 1.0E-34 T 26-04-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS01080 cd36345d647708d6026c671ec8eb0342 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 24 31 1.0E-34 T 26-04-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS01080 cd36345d647708d6026c671ec8eb0342 264 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 68 76 1.0E-34 T 26-04-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS01080 cd36345d647708d6026c671ec8eb0342 264 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 18 263 29.564 T 26-04-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS01055 3665739585d19134b9f3b1c501b063a8 166 SUPERFAMILY SSF52255 9 162 2.09E-66 T 26-04-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4V04_RS01055 3665739585d19134b9f3b1c501b063a8 166 Gene3D G3DSA:3.40.50.7700 4 161 9.4E-75 T 26-04-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4V04_RS01055 3665739585d19134b9f3b1c501b063a8 166 Pfam PF00731 AIR carboxylase 10 157 3.9E-64 T 26-04-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4V04_RS01055 3665739585d19134b9f3b1c501b063a8 166 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 10 163 31.977 T 26-04-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4V04_RS01055 3665739585d19134b9f3b1c501b063a8 166 SMART SM01001 8 159 9.9E-102 T 26-04-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4V04_RS01055 3665739585d19134b9f3b1c501b063a8 166 PIRSF PIRSF001338 5 164 3.2E-66 T 26-04-2017 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 A4V04_RS01055 3665739585d19134b9f3b1c501b063a8 166 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 10 159 8.6E-65 T 26-04-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4V04_RS07160 348f36dc2b5d1f918174957206f04f43 346 Pfam PF13609 Gram-negative porin 7 317 6.9E-41 T 26-04-2017 A4V04_RS07160 348f36dc2b5d1f918174957206f04f43 346 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 50 61 1.5E-5 T 26-04-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 A4V04_RS07160 348f36dc2b5d1f918174957206f04f43 346 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 94 104 1.5E-5 T 26-04-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 A4V04_RS07160 348f36dc2b5d1f918174957206f04f43 346 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 294 311 1.5E-5 T 26-04-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 A4V04_RS07160 348f36dc2b5d1f918174957206f04f43 346 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 221 233 1.5E-5 T 26-04-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 A4V04_RS07160 348f36dc2b5d1f918174957206f04f43 346 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 155 166 1.5E-5 T 26-04-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 A4V04_RS07160 348f36dc2b5d1f918174957206f04f43 346 Gene3D G3DSA:2.40.160.10 20 346 3.4E-63 T 26-04-2017 IPR023614 Porin domain A4V04_RS07160 348f36dc2b5d1f918174957206f04f43 346 PRINTS PR00184 Neisseria sp. porin signature 52 77 6.1E-9 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS07160 348f36dc2b5d1f918174957206f04f43 346 PRINTS PR00184 Neisseria sp. porin signature 154 171 6.1E-9 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS07160 348f36dc2b5d1f918174957206f04f43 346 PRINTS PR00184 Neisseria sp. porin signature 291 315 6.1E-9 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS07160 348f36dc2b5d1f918174957206f04f43 346 SUPERFAMILY SSF56935 21 346 3.14E-47 T 26-04-2017 A4V04_RS10920 f3ce407f07f1aff065789715662999ca 581 SMART SM00387 470 580 3.7E-12 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10920 f3ce407f07f1aff065789715662999ca 581 Gene3D G3DSA:1.10.287.130 362 415 1.3E-9 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10920 f3ce407f07f1aff065789715662999ca 581 Gene3D G3DSA:3.30.565.10 416 579 1.8E-25 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10920 f3ce407f07f1aff065789715662999ca 581 SUPERFAMILY SSF53850 41 289 2.63E-19 T 26-04-2017 A4V04_RS10920 f3ce407f07f1aff065789715662999ca 581 SMART SM00388 360 430 8.0E-14 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10920 f3ce407f07f1aff065789715662999ca 581 Pfam PF00512 His Kinase A (phospho-acceptor) domain 362 427 2.7E-12 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10920 f3ce407f07f1aff065789715662999ca 581 Gene3D G3DSA:3.40.190.10 113 194 1.6E-4 T 26-04-2017 A4V04_RS10920 f3ce407f07f1aff065789715662999ca 581 PRINTS PR00344 Bacterial sensor protein C-terminal signature 540 558 3.1E-6 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS10920 f3ce407f07f1aff065789715662999ca 581 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 525 3.1E-6 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS10920 f3ce407f07f1aff065789715662999ca 581 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 34 271 4.2E-25 T 26-04-2017 A4V04_RS10920 f3ce407f07f1aff065789715662999ca 581 SUPERFAMILY SSF55874 416 576 1.57E-22 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS10920 f3ce407f07f1aff065789715662999ca 581 SUPERFAMILY SSF47384 355 427 1.12E-11 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS10920 f3ce407f07f1aff065789715662999ca 581 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 475 576 1.1E-10 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS08710 edc6b01fb77b8e2df5a4381732eb4b41 588 Gene3D G3DSA:3.90.700.10 390 520 2.2E-24 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08710 edc6b01fb77b8e2df5a4381732eb4b41 588 SUPERFAMILY SSF56425 388 529 3.74E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08710 edc6b01fb77b8e2df5a4381732eb4b41 588 Gene3D G3DSA:3.50.50.60 128 370 1.5E-100 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08710 edc6b01fb77b8e2df5a4381732eb4b41 588 Gene3D G3DSA:3.50.50.60 525 586 1.5E-100 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08710 edc6b01fb77b8e2df5a4381732eb4b41 588 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 136 581 1.7E-145 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS08710 edc6b01fb77b8e2df5a4381732eb4b41 588 Pfam PF04205 FMN-binding domain 36 107 5.2E-15 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS08710 edc6b01fb77b8e2df5a4381732eb4b41 588 SMART SM00900 36 110 1.0E-12 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS08710 edc6b01fb77b8e2df5a4381732eb4b41 588 Pfam PF00890 FAD binding domain 136 567 3.8E-84 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08710 edc6b01fb77b8e2df5a4381732eb4b41 588 SUPERFAMILY SSF51905 127 387 3.87E-62 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08710 edc6b01fb77b8e2df5a4381732eb4b41 588 SUPERFAMILY SSF51905 528 585 3.87E-62 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS09640 beb7ee48e7a595ef9701ec1058142ec5 622 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 131 148 2.5E-68 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS09640 beb7ee48e7a595ef9701ec1058142ec5 622 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 2.5E-68 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS09640 beb7ee48e7a595ef9701ec1058142ec5 622 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 2.5E-68 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS09640 beb7ee48e7a595ef9701ec1058142ec5 622 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 2.5E-68 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS09640 beb7ee48e7a595ef9701ec1058142ec5 622 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 2.5E-68 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS09640 beb7ee48e7a595ef9701ec1058142ec5 622 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 2.5E-68 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS09640 beb7ee48e7a595ef9701ec1058142ec5 622 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 2.5E-68 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS09640 beb7ee48e7a595ef9701ec1058142ec5 622 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 2.5E-68 T 26-04-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS09640 beb7ee48e7a595ef9701ec1058142ec5 622 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 3.0E-6 T 26-04-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS09640 beb7ee48e7a595ef9701ec1058142ec5 622 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 3.0E-6 T 26-04-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS09640 beb7ee48e7a595ef9701ec1058142ec5 622 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 3.0E-6 T 26-04-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4V04_RS09640 beb7ee48e7a595ef9701ec1058142ec5 622 Pfam PF01578 Cytochrome C assembly protein 89 295 1.5E-41 T 26-04-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A4V04_RS09640 beb7ee48e7a595ef9701ec1058142ec5 622 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 613 5.2E-58 T 26-04-2017 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal A4V04_RS02550 52bb8199961b5bb610edabf676f2dca0 636 Pfam PF01609 Transposase DDE domain 213 541 3.4E-16 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS02550 52bb8199961b5bb610edabf676f2dca0 636 SUPERFAMILY SSF53098 193 445 1.74E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS02550 52bb8199961b5bb610edabf676f2dca0 636 SUPERFAMILY SSF53098 480 555 1.74E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS12090 52bb8199961b5bb610edabf676f2dca0 636 Pfam PF01609 Transposase DDE domain 213 541 3.4E-16 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS12090 52bb8199961b5bb610edabf676f2dca0 636 SUPERFAMILY SSF53098 193 445 1.74E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS12090 52bb8199961b5bb610edabf676f2dca0 636 SUPERFAMILY SSF53098 480 555 1.74E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS12485 52bb8199961b5bb610edabf676f2dca0 636 Pfam PF01609 Transposase DDE domain 213 541 3.4E-16 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS12485 52bb8199961b5bb610edabf676f2dca0 636 SUPERFAMILY SSF53098 193 445 1.74E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS12485 52bb8199961b5bb610edabf676f2dca0 636 SUPERFAMILY SSF53098 480 555 1.74E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS08380 52bb8199961b5bb610edabf676f2dca0 636 Pfam PF01609 Transposase DDE domain 213 541 3.4E-16 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS08380 52bb8199961b5bb610edabf676f2dca0 636 SUPERFAMILY SSF53098 193 445 1.74E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS08380 52bb8199961b5bb610edabf676f2dca0 636 SUPERFAMILY SSF53098 480 555 1.74E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS08130 52bb8199961b5bb610edabf676f2dca0 636 Pfam PF01609 Transposase DDE domain 213 541 3.4E-16 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS08130 52bb8199961b5bb610edabf676f2dca0 636 SUPERFAMILY SSF53098 193 445 1.74E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS08130 52bb8199961b5bb610edabf676f2dca0 636 SUPERFAMILY SSF53098 480 555 1.74E-11 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS09210 ff4381cb5ed279374dfc0b20df9bc25b 234 SUPERFAMILY SSF54862 57 216 7.95E-32 T 26-04-2017 A4V04_RS09210 ff4381cb5ed279374dfc0b20df9bc25b 234 Gene3D G3DSA:3.30.70.20 162 193 2.7E-12 T 26-04-2017 A4V04_RS09210 ff4381cb5ed279374dfc0b20df9bc25b 234 Gene3D G3DSA:3.30.70.20 125 161 1.4E-13 T 26-04-2017 A4V04_RS09210 ff4381cb5ed279374dfc0b20df9bc25b 234 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 155 166 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS09210 ff4381cb5ed279374dfc0b20df9bc25b 234 Gene3D G3DSA:3.30.70.20 194 215 1.4E-11 T 26-04-2017 A4V04_RS09210 ff4381cb5ed279374dfc0b20df9bc25b 234 Gene3D G3DSA:3.30.70.20 57 124 1.4E-11 T 26-04-2017 A4V04_RS09210 ff4381cb5ed279374dfc0b20df9bc25b 234 Pfam PF13247 4Fe-4S dicluster domain 117 200 5.7E-9 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS09415 7b1b2d9fa942caa3b8ac9587283e7323 444 SUPERFAMILY SSF51261 234 442 1.99E-36 T 26-04-2017 IPR011055 Duplicated hybrid motif A4V04_RS09415 7b1b2d9fa942caa3b8ac9587283e7323 444 Pfam PF01551 Peptidase family M23 346 438 5.8E-24 T 26-04-2017 IPR016047 Peptidase M23 A4V04_RS09415 7b1b2d9fa942caa3b8ac9587283e7323 444 Gene3D G3DSA:2.70.70.10 302 443 4.6E-32 T 26-04-2017 A4V04_RS09095 c0581cb3ca9f19fdbdc7dd935d965fb6 610 Pfam PF00501 AMP-binding enzyme 22 477 2.0E-86 T 26-04-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4V04_RS09095 c0581cb3ca9f19fdbdc7dd935d965fb6 610 Gene3D G3DSA:3.40.50.980 16 195 2.4E-35 T 26-04-2017 A4V04_RS09095 c0581cb3ca9f19fdbdc7dd935d965fb6 610 Gene3D G3DSA:3.40.50.980 344 407 2.2E-34 T 26-04-2017 A4V04_RS09095 c0581cb3ca9f19fdbdc7dd935d965fb6 610 Gene3D G3DSA:3.40.50.980 196 287 2.2E-34 T 26-04-2017 A4V04_RS09095 c0581cb3ca9f19fdbdc7dd935d965fb6 610 Gene3D G3DSA:2.30.38.10 413 471 5.4E-17 T 26-04-2017 A4V04_RS09095 c0581cb3ca9f19fdbdc7dd935d965fb6 610 PRINTS PR00154 AMP-binding signature 184 195 9.1E-5 T 26-04-2017 IPR020459 AMP-binding A4V04_RS09095 c0581cb3ca9f19fdbdc7dd935d965fb6 610 PRINTS PR00154 AMP-binding signature 196 204 9.1E-5 T 26-04-2017 IPR020459 AMP-binding A4V04_RS09095 c0581cb3ca9f19fdbdc7dd935d965fb6 610 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 26-04-2017 IPR020845 AMP-binding, conserved site A4V04_RS09095 c0581cb3ca9f19fdbdc7dd935d965fb6 610 SUPERFAMILY SSF56801 15 292 4.84E-108 T 26-04-2017 A4V04_RS09095 c0581cb3ca9f19fdbdc7dd935d965fb6 610 SUPERFAMILY SSF56801 347 606 4.84E-108 T 26-04-2017 A4V04_RS09095 c0581cb3ca9f19fdbdc7dd935d965fb6 610 Gene3D G3DSA:3.30.300.30 475 595 6.2E-5 T 26-04-2017 A4V04_RS03105 009cc299223b64571605e8ae2a960c8c 286 Pfam PF04228 Putative neutral zinc metallopeptidase 1 281 7.9E-122 T 26-04-2017 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative A4V04_RS03105 009cc299223b64571605e8ae2a960c8c 286 Gene3D G3DSA:3.40.390.10 56 169 6.1E-5 T 26-04-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A4V04_RS05095 7c722a979da6e56dcd48e71282146d16 357 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 35 278 4.6E-55 T 26-04-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 A4V04_RS05095 7c722a979da6e56dcd48e71282146d16 357 PIRSF PIRSF006470 1 355 9.2E-66 T 26-04-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 A4V04_RS07930 bfcb380cd96a7fd054ea286e978e88bf 685 Hamap MF_02023 Dissimilatory sulfite reductase. 1 673 51.453 T 26-04-2017 IPR032897 Dissimilatory sulfite reductase GO:0016002|GO:0020037|GO:0070814 A4V04_RS07930 bfcb380cd96a7fd054ea286e978e88bf 685 Gene3D G3DSA:1.10.710.10 137 181 4.5E-27 T 26-04-2017 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 A4V04_RS07930 bfcb380cd96a7fd054ea286e978e88bf 685 Gene3D G3DSA:1.10.710.10 291 480 4.5E-27 T 26-04-2017 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 A4V04_RS07930 bfcb380cd96a7fd054ea286e978e88bf 685 SUPERFAMILY SSF48695 300 504 9.76E-43 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS07930 bfcb380cd96a7fd054ea286e978e88bf 685 SUPERFAMILY SSF48695 538 668 9.76E-43 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS07930 bfcb380cd96a7fd054ea286e978e88bf 685 SUPERFAMILY SSF48695 138 244 9.76E-43 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS07930 bfcb380cd96a7fd054ea286e978e88bf 685 Pfam PF13435 Cytochrome c554 and c-prime 144 166 5.1E-4 T 26-04-2017 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 A4V04_RS00120 3125cb7d9115937cb809602adf2ea925 207 SUPERFAMILY SSF52218 112 177 1.47E-9 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS00120 3125cb7d9115937cb809602adf2ea925 207 SUPERFAMILY SSF52218 25 52 1.47E-9 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS00120 3125cb7d9115937cb809602adf2ea925 207 Gene3D G3DSA:3.40.50.360 26 198 1.8E-6 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS00120 3125cb7d9115937cb809602adf2ea925 207 Pfam PF12682 Flavodoxin 57 180 3.4E-13 T 26-04-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A4V04_RS05900 94b5ea145a34eae2cae348f2607c4542 241 PIRSF PIRSF005650 4 241 3.2E-92 T 26-04-2017 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A4V04_RS05900 94b5ea145a34eae2cae348f2607c4542 241 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 9 240 1.9E-98 T 26-04-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A4V04_RS05900 94b5ea145a34eae2cae348f2607c4542 241 SUPERFAMILY SSF53633 7 240 4.06E-72 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS05900 94b5ea145a34eae2cae348f2607c4542 241 Gene3D G3DSA:3.40.1160.10 3 240 6.0E-87 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS05900 94b5ea145a34eae2cae348f2607c4542 241 Pfam PF00696 Amino acid kinase family 10 219 5.4E-27 T 26-04-2017 IPR001048 Aspartate/glutamate/uridylate kinase A4V04_RS05900 94b5ea145a34eae2cae348f2607c4542 241 Hamap MF_01220_B Uridylate kinase [pyrH]. 7 240 44.229 T 26-04-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A4V04_RS07565 f952439bfa6ba7b114d8ec94b204f191 503 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 86 101 - T 26-04-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4V04_RS07565 f952439bfa6ba7b114d8ec94b204f191 503 PRINTS PR00175 Sodium/alanine symporter signature 86 108 2.5E-56 T 26-04-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4V04_RS07565 f952439bfa6ba7b114d8ec94b204f191 503 PRINTS PR00175 Sodium/alanine symporter signature 353 375 2.5E-56 T 26-04-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4V04_RS07565 f952439bfa6ba7b114d8ec94b204f191 503 PRINTS PR00175 Sodium/alanine symporter signature 416 436 2.5E-56 T 26-04-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4V04_RS07565 f952439bfa6ba7b114d8ec94b204f191 503 PRINTS PR00175 Sodium/alanine symporter signature 204 223 2.5E-56 T 26-04-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4V04_RS07565 f952439bfa6ba7b114d8ec94b204f191 503 PRINTS PR00175 Sodium/alanine symporter signature 295 313 2.5E-56 T 26-04-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4V04_RS07565 f952439bfa6ba7b114d8ec94b204f191 503 PRINTS PR00175 Sodium/alanine symporter signature 176 194 2.5E-56 T 26-04-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4V04_RS07565 f952439bfa6ba7b114d8ec94b204f191 503 Pfam PF01235 Sodium:alanine symporter family 50 459 5.9E-154 T 26-04-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4V04_RS07565 f952439bfa6ba7b114d8ec94b204f191 503 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 447 4.6E-144 T 26-04-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 SMART SM00363 353 412 0.0024 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 Gene3D G3DSA:3.40.50.620 17 243 1.3E-78 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 Pfam PF00579 tRNA synthetases class I (W and Y) 48 333 3.8E-76 T 26-04-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 14 413 47.04 T 26-04-2017 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 SUPERFAMILY SSF55174 314 412 2.88E-17 T 26-04-2017 A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 Pfam PF01479 S4 domain 355 397 2.2E-8 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 SUPERFAMILY SSF52374 20 332 2.95E-91 T 26-04-2017 A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 68 - T 26-04-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 62 84 2.7E-25 T 26-04-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 177 192 2.7E-25 T 26-04-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 227 239 2.7E-25 T 26-04-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 194 216 2.7E-25 T 26-04-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 Gene3D G3DSA:3.10.290.10 344 413 1.5E-21 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 Gene3D G3DSA:1.10.240.10 244 343 8.4E-37 T 26-04-2017 A4V04_RS12315 f7100f372a3c3195a709ea9fe05a3586 416 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 21 413 3.7E-122 T 26-04-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4V04_RS12185 f2f752f50e9e44fe3182b8fa89b4b3f9 454 SUPERFAMILY SSF51905 14 257 1.56E-41 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12185 f2f752f50e9e44fe3182b8fa89b4b3f9 454 SUPERFAMILY SSF51905 405 453 1.56E-41 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12185 f2f752f50e9e44fe3182b8fa89b4b3f9 454 Gene3D G3DSA:3.50.50.60 402 451 3.4E-56 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12185 f2f752f50e9e44fe3182b8fa89b4b3f9 454 Gene3D G3DSA:3.50.50.60 26 252 3.4E-56 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12185 f2f752f50e9e44fe3182b8fa89b4b3f9 454 Pfam PF00890 FAD binding domain 30 432 7.4E-56 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS12185 f2f752f50e9e44fe3182b8fa89b4b3f9 454 SUPERFAMILY SSF56425 270 398 1.79E-31 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS12185 f2f752f50e9e44fe3182b8fa89b4b3f9 454 Gene3D G3DSA:3.90.700.10 271 397 6.8E-32 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02385 aaa2e097d1103442c52702539c11b1d1 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 40 59 1.3E-8 T 26-04-2017 A4V04_RS02385 aaa2e097d1103442c52702539c11b1d1 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 429 451 1.3E-8 T 26-04-2017 A4V04_RS02385 aaa2e097d1103442c52702539c11b1d1 481 SUPERFAMILY SSF51905 424 481 6.5E-64 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02385 aaa2e097d1103442c52702539c11b1d1 481 SUPERFAMILY SSF51905 34 285 6.5E-64 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02385 aaa2e097d1103442c52702539c11b1d1 481 SUPERFAMILY SSF56425 293 425 2.84E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02385 aaa2e097d1103442c52702539c11b1d1 481 Gene3D G3DSA:3.90.700.10 293 416 9.7E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02385 aaa2e097d1103442c52702539c11b1d1 481 Pfam PF00890 FAD binding domain 39 465 2.7E-83 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02385 aaa2e097d1103442c52702539c11b1d1 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 61 4.6E-8 T 26-04-2017 A4V04_RS02385 aaa2e097d1103442c52702539c11b1d1 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 465 480 4.6E-8 T 26-04-2017 A4V04_RS02385 aaa2e097d1103442c52702539c11b1d1 481 Gene3D G3DSA:3.50.50.60 27 268 8.0E-100 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02385 aaa2e097d1103442c52702539c11b1d1 481 Gene3D G3DSA:3.50.50.60 421 481 8.0E-100 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02385 aaa2e097d1103442c52702539c11b1d1 481 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 39 477 2.2E-121 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS06345 89632befb5c824f980258fa78d5907ba 97 Pfam PF04956 TrbC/VIRB2 family 6 94 2.0E-12 T 26-04-2017 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 A4V04_RS02805 944ed41a6cdb71cb898818ddb4647258 380 SUPERFAMILY SSF55174 79 131 2.65E-8 T 26-04-2017 A4V04_RS02805 944ed41a6cdb71cb898818ddb4647258 380 SMART SM00363 80 141 6.5E-7 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS02805 944ed41a6cdb71cb898818ddb4647258 380 Pfam PF01479 S4 domain 80 126 1.7E-7 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS02805 944ed41a6cdb71cb898818ddb4647258 380 Pfam PF00849 RNA pseudouridylate synthase 158 308 6.5E-31 T 26-04-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS02805 944ed41a6cdb71cb898818ddb4647258 380 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 77 375 1.3E-77 T 26-04-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS02805 944ed41a6cdb71cb898818ddb4647258 380 Gene3D G3DSA:3.10.290.10 79 129 8.4E-5 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS02805 944ed41a6cdb71cb898818ddb4647258 380 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 197 211 - T 26-04-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS02805 944ed41a6cdb71cb898818ddb4647258 380 SUPERFAMILY SSF55120 151 377 2.3E-61 T 26-04-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS00015 0e4216d70a32ae45c1dbcd54e21c06d5 112 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 26-04-2017 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4V04_RS00015 0e4216d70a32ae45c1dbcd54e21c06d5 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 111 3.2E-49 T 26-04-2017 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 A4V04_RS00015 0e4216d70a32ae45c1dbcd54e21c06d5 112 SUPERFAMILY SSF54292 5 109 3.33E-31 T 26-04-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4V04_RS00015 0e4216d70a32ae45c1dbcd54e21c06d5 112 Gene3D G3DSA:3.10.20.30 1 101 1.5E-32 T 26-04-2017 IPR012675 Beta-grasp domain A4V04_RS00015 0e4216d70a32ae45c1dbcd54e21c06d5 112 PRINTS PR00355 Adrenodoxin signature 60 74 6.9E-9 T 26-04-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4V04_RS00015 0e4216d70a32ae45c1dbcd54e21c06d5 112 PRINTS PR00355 Adrenodoxin signature 83 91 6.9E-9 T 26-04-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4V04_RS00015 0e4216d70a32ae45c1dbcd54e21c06d5 112 PRINTS PR00355 Adrenodoxin signature 42 52 6.9E-9 T 26-04-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4V04_RS00015 0e4216d70a32ae45c1dbcd54e21c06d5 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 91 2.0E-14 T 26-04-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4V04_RS08885 fda18883cd941df5a9919d163b349661 589 SUPERFAMILY SSF53850 21 281 4.53E-23 T 26-04-2017 A4V04_RS08885 fda18883cd941df5a9919d163b349661 589 SUPERFAMILY SSF47384 356 435 1.1E-6 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS08885 fda18883cd941df5a9919d163b349661 589 Gene3D G3DSA:3.30.565.10 423 586 2.8E-26 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS08885 fda18883cd941df5a9919d163b349661 589 SMART SM00388 362 436 0.0012 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS08885 fda18883cd941df5a9919d163b349661 589 Gene3D G3DSA:3.40.190.10 109 215 5.8E-7 T 26-04-2017 A4V04_RS08885 fda18883cd941df5a9919d163b349661 589 Pfam PF00512 His Kinase A (phospho-acceptor) domain 366 434 4.3E-7 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS08885 fda18883cd941df5a9919d163b349661 589 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 33 262 3.7E-29 T 26-04-2017 A4V04_RS08885 fda18883cd941df5a9919d163b349661 589 SMART SM00387 476 584 1.1E-14 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS08885 fda18883cd941df5a9919d163b349661 589 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 476 581 1.1E-10 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS08885 fda18883cd941df5a9919d163b349661 589 Gene3D G3DSA:1.10.287.130 365 422 8.2E-5 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS08885 fda18883cd941df5a9919d163b349661 589 SUPERFAMILY SSF55874 427 582 1.14E-26 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS08885 fda18883cd941df5a9919d163b349661 589 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 529 4.1E-6 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS08885 fda18883cd941df5a9919d163b349661 589 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 562 4.1E-6 T 26-04-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4V04_RS11005 20a41216cfd33e16c7d1541b399f3ef2 807 Gene3D G3DSA:3.40.50.410 245 424 8.7E-18 T 26-04-2017 IPR002035 von Willebrand factor, type A A4V04_RS11005 20a41216cfd33e16c7d1541b399f3ef2 807 SUPERFAMILY SSF53300 249 418 4.3E-24 T 26-04-2017 IPR002035 von Willebrand factor, type A A4V04_RS11005 20a41216cfd33e16c7d1541b399f3ef2 807 Pfam PF00092 von Willebrand factor type A domain 251 417 4.8E-12 T 26-04-2017 IPR002035 von Willebrand factor, type A A4V04_RS11005 20a41216cfd33e16c7d1541b399f3ef2 807 SMART SM00327 249 429 3.6E-17 T 26-04-2017 IPR002035 von Willebrand factor, type A A4V04_RS11005 20a41216cfd33e16c7d1541b399f3ef2 807 SMART SM00609 1 124 0.001 T 26-04-2017 IPR013694 VIT domain A4V04_RS11005 20a41216cfd33e16c7d1541b399f3ef2 807 Pfam PF08487 Vault protein inter-alpha-trypsin domain 11 122 3.1E-20 T 26-04-2017 IPR013694 VIT domain A4V04_RS04205 98d2c97a6d24d575baa84fde4f879f7b 324 SUPERFAMILY SSF53850 91 298 5.12E-17 T 26-04-2017 A4V04_RS04205 98d2c97a6d24d575baa84fde4f879f7b 324 Gene3D G3DSA:1.10.10.10 6 88 6.7E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04205 98d2c97a6d24d575baa84fde4f879f7b 324 SUPERFAMILY SSF46785 6 91 8.94E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04205 98d2c97a6d24d575baa84fde4f879f7b 324 Pfam PF03466 LysR substrate binding domain 93 296 2.7E-14 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS04205 98d2c97a6d24d575baa84fde4f879f7b 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 7.7E-15 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS04205 98d2c97a6d24d575baa84fde4f879f7b 324 Gene3D G3DSA:3.40.190.10 169 268 1.1E-7 T 26-04-2017 A4V04_RS11795 023f8ebe63d8489a2f487053c1c4dad9 103 Gene3D G3DSA:1.10.260.40 21 83 5.2E-14 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS11795 023f8ebe63d8489a2f487053c1c4dad9 103 Pfam PF13744 Helix-turn-helix domain 27 87 8.2E-12 T 26-04-2017 A4V04_RS11795 023f8ebe63d8489a2f487053c1c4dad9 103 SMART SM00530 31 86 1.2E-6 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS11795 023f8ebe63d8489a2f487053c1c4dad9 103 SUPERFAMILY SSF47413 18 87 7.32E-16 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS04660 78cc9906c4cae166f31fd1b79d7eaf6e 299 Pfam PF12833 Helix-turn-helix domain 219 294 7.0E-18 T 26-04-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4V04_RS04660 78cc9906c4cae166f31fd1b79d7eaf6e 299 SMART SM00342 210 293 3.1E-25 T 26-04-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4V04_RS04660 78cc9906c4cae166f31fd1b79d7eaf6e 299 Gene3D G3DSA:1.10.10.60 197 246 9.8E-12 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS04660 78cc9906c4cae166f31fd1b79d7eaf6e 299 Gene3D G3DSA:1.10.10.60 247 295 1.3E-13 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS04660 78cc9906c4cae166f31fd1b79d7eaf6e 299 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 247 289 - T 26-04-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4V04_RS04660 78cc9906c4cae166f31fd1b79d7eaf6e 299 Pfam PF02311 AraC-like ligand binding domain 39 165 1.2E-9 T 26-04-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A4V04_RS04660 78cc9906c4cae166f31fd1b79d7eaf6e 299 SUPERFAMILY SSF46689 247 297 6.27E-11 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS04660 78cc9906c4cae166f31fd1b79d7eaf6e 299 SUPERFAMILY SSF46689 197 244 4.03E-5 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS04660 78cc9906c4cae166f31fd1b79d7eaf6e 299 SUPERFAMILY SSF51182 16 87 1.42E-8 T 26-04-2017 IPR011051 RmlC-like cupin domain A4V04_RS04660 78cc9906c4cae166f31fd1b79d7eaf6e 299 Gene3D G3DSA:2.60.120.10 24 89 5.6E-9 T 26-04-2017 IPR014710 RmlC-like jelly roll fold A4V04_RS11455 dd4b0d17db87a09931b6aaa25304edba 150 Gene3D G3DSA:3.40.630.30 12 136 4.3E-23 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS11455 dd4b0d17db87a09931b6aaa25304edba 150 SUPERFAMILY SSF55729 1 146 4.75E-23 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS11455 dd4b0d17db87a09931b6aaa25304edba 150 Pfam PF13508 Acetyltransferase (GNAT) domain 49 114 4.3E-11 T 26-04-2017 IPR000182 GNAT domain GO:0008080 A4V04_RS02445 20d93b79cce2c5381226f8caee4e6168 365 SUPERFAMILY SSF51735 1 336 3.44E-86 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS02445 20d93b79cce2c5381226f8caee4e6168 365 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 325 8.3E-88 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS02445 20d93b79cce2c5381226f8caee4e6168 365 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 5 339 4.7E-140 T 26-04-2017 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 A4V04_RS02445 20d93b79cce2c5381226f8caee4e6168 365 Gene3D G3DSA:3.90.25.10 192 349 5.4E-52 T 26-04-2017 A4V04_RS02445 20d93b79cce2c5381226f8caee4e6168 365 Gene3D G3DSA:3.40.50.720 3 191 3.0E-58 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS04350 0e2e3f908c0ea6c22a27b6a763c43bc8 320 Gene3D G3DSA:1.10.10.10 1 45 4.6E-6 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04350 0e2e3f908c0ea6c22a27b6a763c43bc8 320 Pfam PF02661 Fic/DOC family 177 270 1.1E-12 T 26-04-2017 IPR003812 Fido domain A4V04_RS04350 0e2e3f908c0ea6c22a27b6a763c43bc8 320 SUPERFAMILY SSF140931 153 315 7.19E-22 T 26-04-2017 IPR003812 Fido domain A4V04_RS04350 0e2e3f908c0ea6c22a27b6a763c43bc8 320 Gene3D G3DSA:1.10.3290.10 91 316 2.0E-38 T 26-04-2017 IPR003812 Fido domain A4V04_RS02675 943f2e4222258320ad4a675a5f72ee34 91 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 26.569 T 26-04-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 A4V04_RS02675 943f2e4222258320ad4a675a5f72ee34 91 SUPERFAMILY SSF111148 1 90 4.45E-37 T 26-04-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 A4V04_RS02675 943f2e4222258320ad4a675a5f72ee34 91 PIRSF PIRSF029827 1 90 1.8E-36 T 26-04-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 A4V04_RS02675 943f2e4222258320ad4a675a5f72ee34 91 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 75 4.0E-19 T 26-04-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 A4V04_RS02675 943f2e4222258320ad4a675a5f72ee34 91 Gene3D G3DSA:1.10.3880.10 1 90 2.5E-38 T 26-04-2017 A4V04_RS02675 943f2e4222258320ad4a675a5f72ee34 91 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 3.2E-40 T 26-04-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 A4V04_RS11310 7b121cce6c452ae9e6077740e884c96f 173 Gene3D G3DSA:3.30.230.10 83 166 3.4E-34 T 26-04-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4V04_RS11310 7b121cce6c452ae9e6077740e884c96f 173 Gene3D G3DSA:3.30.160.20 16 78 1.4E-22 T 26-04-2017 IPR014720 Double-stranded RNA-binding domain A4V04_RS11310 7b121cce6c452ae9e6077740e884c96f 173 ProSitePatterns PS00585 Ribosomal protein S5 signature. 35 67 - T 26-04-2017 IPR018192 Ribosomal protein S5, N-terminal, conserved site A4V04_RS11310 7b121cce6c452ae9e6077740e884c96f 173 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 170 33.214 T 26-04-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4V04_RS11310 7b121cce6c452ae9e6077740e884c96f 173 Pfam PF03719 Ribosomal protein S5, C-terminal domain 94 164 4.0E-31 T 26-04-2017 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 A4V04_RS11310 7b121cce6c452ae9e6077740e884c96f 173 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 18 170 6.1E-62 T 26-04-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4V04_RS11310 7b121cce6c452ae9e6077740e884c96f 173 SUPERFAMILY SSF54211 86 166 2.02E-27 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS11310 7b121cce6c452ae9e6077740e884c96f 173 Pfam PF00333 Ribosomal protein S5, N-terminal domain 19 82 2.3E-22 T 26-04-2017 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4V04_RS11310 7b121cce6c452ae9e6077740e884c96f 173 SUPERFAMILY SSF54768 15 83 6.38E-19 T 26-04-2017 A4V04_RS04880 4aa6cb6343611d8fc913fcfa856f852f 280 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 168 178 - T 26-04-2017 IPR024002 Formate/nitrite transporter, conserved site A4V04_RS04880 4aa6cb6343611d8fc913fcfa856f852f 280 Gene3D G3DSA:1.20.1080.10 28 278 5.8E-80 T 26-04-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A4V04_RS04880 4aa6cb6343611d8fc913fcfa856f852f 280 Pfam PF01226 Formate/nitrite transporter 9 273 5.2E-74 T 26-04-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 A4V04_RS04880 4aa6cb6343611d8fc913fcfa856f852f 280 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 20 277 9.0E-72 T 26-04-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 A4V04_RS04880 4aa6cb6343611d8fc913fcfa856f852f 280 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 78 87 - T 26-04-2017 IPR024002 Formate/nitrite transporter, conserved site A4V04_RS03545 6a552bd6706db8020162d847f15402ff 600 Gene3D G3DSA:3.90.700.10 390 529 4.7E-23 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03545 6a552bd6706db8020162d847f15402ff 600 SUPERFAMILY SSF51905 119 380 8.09E-47 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03545 6a552bd6706db8020162d847f15402ff 600 SUPERFAMILY SSF51905 537 598 8.09E-47 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03545 6a552bd6706db8020162d847f15402ff 600 Pfam PF04205 FMN-binding domain 35 106 1.1E-10 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS03545 6a552bd6706db8020162d847f15402ff 600 Gene3D G3DSA:3.50.50.60 119 363 4.3E-66 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03545 6a552bd6706db8020162d847f15402ff 600 Gene3D G3DSA:3.50.50.60 534 598 4.3E-66 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03545 6a552bd6706db8020162d847f15402ff 600 Pfam PF00890 FAD binding domain 135 572 9.4E-59 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03545 6a552bd6706db8020162d847f15402ff 600 SMART SM00900 35 109 9.5E-15 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS03545 6a552bd6706db8020162d847f15402ff 600 SUPERFAMILY SSF56425 393 538 2.88E-21 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS07255 8810b671834b36499d674a5ceae86214 412 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 281 375 1.9E-11 T 26-04-2017 IPR026843 Nuclease SbcCD subunit D, C-terminal domain A4V04_RS07255 8810b671834b36499d674a5ceae86214 412 SUPERFAMILY SSF56300 1 340 5.01E-53 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS07255 8810b671834b36499d674a5ceae86214 412 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 259 2.9E-64 T 26-04-2017 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 A4V04_RS07255 8810b671834b36499d674a5ceae86214 412 Gene3D G3DSA:3.60.21.10 1 278 3.4E-60 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS07255 8810b671834b36499d674a5ceae86214 412 Pfam PF00149 Calcineurin-like phosphoesterase 1 104 4.3E-13 T 26-04-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4V04_RS09685 a70fc5981b124f1266a16f05a16ad18b 87 SUPERFAMILY SSF48695 21 85 6.29E-8 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS09685 a70fc5981b124f1266a16f05a16ad18b 87 Pfam PF14537 Cytochrome c3 28 86 4.3E-7 T 26-04-2017 A4V04_RS09685 a70fc5981b124f1266a16f05a16ad18b 87 Gene3D G3DSA:3.90.10.10 26 86 1.5E-7 T 26-04-2017 A4V04_RS08525 36e4cc15f2dc62ea4973df63b1f534b0 265 SUPERFAMILY SSF69572 12 254 2.22E-54 T 26-04-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A4V04_RS08525 36e4cc15f2dc62ea4973df63b1f534b0 265 Pfam PF00899 ThiF family 20 164 4.7E-34 T 26-04-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A4V04_RS08525 36e4cc15f2dc62ea4973df63b1f534b0 265 Gene3D G3DSA:3.40.50.720 8 256 4.0E-43 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS08150 33550750c9cd9aa6a22a90b9583309b6 335 Gene3D G3DSA:3.40.50.1400 208 329 1.7E-28 T 26-04-2017 A4V04_RS08150 33550750c9cd9aa6a22a90b9583309b6 335 Gene3D G3DSA:3.40.50.1400 5 207 7.8E-61 T 26-04-2017 A4V04_RS08150 33550750c9cd9aa6a22a90b9583309b6 335 Hamap MF_00323 Ferrochelatase [hemH]. 4 328 34.243 T 26-04-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A4V04_RS08150 33550750c9cd9aa6a22a90b9583309b6 335 TIGRFAM TIGR00109 hemH: ferrochelatase 3 328 1.5E-82 T 26-04-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A4V04_RS08150 33550750c9cd9aa6a22a90b9583309b6 335 SUPERFAMILY SSF53800 4 332 1.31E-92 T 26-04-2017 A4V04_RS08150 33550750c9cd9aa6a22a90b9583309b6 335 ProSitePatterns PS00534 Ferrochelatase signature. 197 215 - T 26-04-2017 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A4V04_RS08150 33550750c9cd9aa6a22a90b9583309b6 335 Pfam PF00762 Ferrochelatase 5 326 1.5E-98 T 26-04-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A4V04_RS03115 c269ee00419f2d34612f54bf82ebb018 512 SUPERFAMILY SSF56425 318 452 4.53E-17 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03115 c269ee00419f2d34612f54bf82ebb018 512 Gene3D G3DSA:3.50.50.60 48 294 2.8E-75 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03115 c269ee00419f2d34612f54bf82ebb018 512 Gene3D G3DSA:3.50.50.60 449 510 2.8E-75 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03115 c269ee00419f2d34612f54bf82ebb018 512 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 64 83 2.6E-5 T 26-04-2017 A4V04_RS03115 c269ee00419f2d34612f54bf82ebb018 512 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 457 479 2.6E-5 T 26-04-2017 A4V04_RS03115 c269ee00419f2d34612f54bf82ebb018 512 SUPERFAMILY SSF51905 53 300 2.16E-47 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03115 c269ee00419f2d34612f54bf82ebb018 512 SUPERFAMILY SSF51905 452 509 2.16E-47 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03115 c269ee00419f2d34612f54bf82ebb018 512 Gene3D G3DSA:3.90.700.10 316 443 3.3E-17 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03115 c269ee00419f2d34612f54bf82ebb018 512 Pfam PF00890 FAD binding domain 63 490 8.6E-52 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10395 0b9e04241e4b5cecc3546c5b05aaae73 216 SUPERFAMILY SSF53474 6 213 1.95E-31 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS10395 0b9e04241e4b5cecc3546c5b05aaae73 216 Gene3D G3DSA:3.40.50.1820 8 211 4.9E-34 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS05830 0cfa5ccf039181ecf8f33d16037bbd1d 263 Gene3D G3DSA:3.30.1330.30 4 105 1.4E-17 T 26-04-2017 IPR029064 50S ribosomal protein L30e-like A4V04_RS05830 0cfa5ccf039181ecf8f33d16037bbd1d 263 Pfam PF00588 SpoU rRNA Methylase family 117 255 5.3E-30 T 26-04-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4V04_RS05830 0cfa5ccf039181ecf8f33d16037bbd1d 263 Gene3D G3DSA:3.40.1280.10 112 261 6.1E-42 T 26-04-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4V04_RS05830 0cfa5ccf039181ecf8f33d16037bbd1d 263 SUPERFAMILY SSF75217 101 261 1.7E-35 T 26-04-2017 IPR029028 Alpha/beta knot methyltransferases A4V04_RS05830 0cfa5ccf039181ecf8f33d16037bbd1d 263 SUPERFAMILY SSF55315 3 105 8.95E-16 T 26-04-2017 IPR029064 50S ribosomal protein L30e-like A4V04_RS11270 f35fe58477c7b433e7aecc8c8f1c225c 86 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 5 82 20.796 T 26-04-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11270 f35fe58477c7b433e7aecc8c8f1c225c 86 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 8 76 1.3E-29 T 26-04-2017 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11270 f35fe58477c7b433e7aecc8c8f1c225c 86 Pfam PF00366 Ribosomal protein S17 12 77 5.6E-26 T 26-04-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11270 f35fe58477c7b433e7aecc8c8f1c225c 86 PRINTS PR00973 Ribosomal protein S17 family signature 57 67 7.4E-5 T 26-04-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11270 f35fe58477c7b433e7aecc8c8f1c225c 86 PRINTS PR00973 Ribosomal protein S17 family signature 25 48 7.4E-5 T 26-04-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11270 f35fe58477c7b433e7aecc8c8f1c225c 86 PRINTS PR00973 Ribosomal protein S17 family signature 67 74 7.4E-5 T 26-04-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11270 f35fe58477c7b433e7aecc8c8f1c225c 86 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 76 8.0E-22 T 26-04-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11270 f35fe58477c7b433e7aecc8c8f1c225c 86 SUPERFAMILY SSF50249 8 83 6.85E-27 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS11270 f35fe58477c7b433e7aecc8c8f1c225c 86 Gene3D G3DSA:2.40.50.140 7 83 3.5E-28 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS03175 9f3d8764535a5dacfbb3812d4647da95 466 Pfam PF00890 FAD binding domain 2 444 4.2E-40 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03175 9f3d8764535a5dacfbb3812d4647da95 466 Gene3D G3DSA:3.90.700.10 236 397 1.3E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03175 9f3d8764535a5dacfbb3812d4647da95 466 SUPERFAMILY SSF56425 234 402 1.54E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03175 9f3d8764535a5dacfbb3812d4647da95 466 SUPERFAMILY SSF51905 2 225 3.25E-25 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03175 9f3d8764535a5dacfbb3812d4647da95 466 SUPERFAMILY SSF51905 405 461 3.25E-25 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03175 9f3d8764535a5dacfbb3812d4647da95 466 Gene3D G3DSA:3.50.50.60 402 461 7.9E-43 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03175 9f3d8764535a5dacfbb3812d4647da95 466 Gene3D G3DSA:3.50.50.60 2 212 7.9E-43 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS05730 06676dfbde9be0f8543303a35d601046 52 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 21 1.4E-5 T 26-04-2017 IPR024973 ESPR domain A4V04_RS01100 160390d2b0999bd2f1a300900bb9f81e 220 Pfam PF10620 Phosphoribosyl-dephospho-CoA transferase MdcG 22 219 6.5E-38 T 26-04-2017 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 A4V04_RS01100 160390d2b0999bd2f1a300900bb9f81e 220 TIGRFAM TIGR03135 malonate_mdcG: malonate decarboxylase holo-[acyl-carrier-protein] synthase 22 218 3.0E-32 T 26-04-2017 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 A4V04_RS03890 8f92ec16ac954690da1b463b237609bb 256 SUPERFAMILY SSF51351 1 249 5.24E-88 T 26-04-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS03890 8f92ec16ac954690da1b463b237609bb 256 Pfam PF00121 Triosephosphate isomerase 5 245 3.6E-89 T 26-04-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS03890 8f92ec16ac954690da1b463b237609bb 256 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 39.438 T 26-04-2017 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS03890 8f92ec16ac954690da1b463b237609bb 256 Gene3D G3DSA:3.20.20.70 1 250 1.1E-98 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS03890 8f92ec16ac954690da1b463b237609bb 256 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 3.7E-66 T 26-04-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS03890 8f92ec16ac954690da1b463b237609bb 256 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 26-04-2017 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4V04_RS03190 5c9b0f186341a556f6c71e7f89594f13 546 SUPERFAMILY SSF52317 292 542 2.75E-79 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS03190 5c9b0f186341a556f6c71e7f89594f13 546 SUPERFAMILY SSF52540 2 268 1.43E-121 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03190 5c9b0f186341a556f6c71e7f89594f13 546 Hamap MF_01227 CTP synthase [pyrG]. 2 540 50.028 T 26-04-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A4V04_RS03190 5c9b0f186341a556f6c71e7f89594f13 546 TIGRFAM TIGR00337 PyrG: CTP synthase 1 534 3.0E-239 T 26-04-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A4V04_RS03190 5c9b0f186341a556f6c71e7f89594f13 546 Gene3D G3DSA:3.40.50.880 291 542 1.6E-91 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS03190 5c9b0f186341a556f6c71e7f89594f13 546 Pfam PF00117 Glutamine amidotransferase class-I 302 534 4.2E-55 T 26-04-2017 IPR017926 Glutamine amidotransferase A4V04_RS03190 5c9b0f186341a556f6c71e7f89594f13 546 Pfam PF06418 CTP synthase N-terminus 3 268 1.1E-126 T 26-04-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A4V04_RS03190 5c9b0f186341a556f6c71e7f89594f13 546 Gene3D G3DSA:3.40.50.300 1 286 1.9E-134 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07310 f7a2d6026e1ae2da9e9a60e956de1d69 474 TIGRFAM TIGR00260 thrC: threonine synthase 99 435 5.5E-74 T 26-04-2017 IPR004450 Threonine synthase-like A4V04_RS07310 f7a2d6026e1ae2da9e9a60e956de1d69 474 Gene3D G3DSA:3.40.50.1100 211 445 9.1E-86 T 26-04-2017 A4V04_RS07310 f7a2d6026e1ae2da9e9a60e956de1d69 474 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 110 124 - T 26-04-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A4V04_RS07310 f7a2d6026e1ae2da9e9a60e956de1d69 474 Gene3D G3DSA:3.40.50.1100 119 210 6.9E-7 T 26-04-2017 A4V04_RS07310 f7a2d6026e1ae2da9e9a60e956de1d69 474 SUPERFAMILY SSF53686 1 472 7.68E-146 T 26-04-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4V04_RS07310 f7a2d6026e1ae2da9e9a60e956de1d69 474 Gene3D G3DSA:3.90.1380.10 1 82 1.6E-26 T 26-04-2017 IPR029144 Threonine synthase, N-terminal A4V04_RS07310 f7a2d6026e1ae2da9e9a60e956de1d69 474 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 110 320 5.6E-14 T 26-04-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4V04_RS07310 f7a2d6026e1ae2da9e9a60e956de1d69 474 Pfam PF14821 Threonine synthase N terminus 2 79 2.5E-24 T 26-04-2017 IPR029144 Threonine synthase, N-terminal A4V04_RS10785 48fcde1aa5c0b883ad9352d5f54b24ce 131 Pfam PF14537 Cytochrome c3 31 125 3.0E-14 T 26-04-2017 A4V04_RS10785 48fcde1aa5c0b883ad9352d5f54b24ce 131 Gene3D G3DSA:3.90.10.10 22 124 5.3E-13 T 26-04-2017 A4V04_RS10785 48fcde1aa5c0b883ad9352d5f54b24ce 131 SUPERFAMILY SSF48695 92 125 1.16E-11 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS10785 48fcde1aa5c0b883ad9352d5f54b24ce 131 SUPERFAMILY SSF48695 21 65 1.16E-11 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS00205 6ea3c16595fe367d966a6442a5998364 135 ProDom PD076485 YNEG CYTOPLASMIC ECS2130 STY1535 4 113 1.0E-33 T 26-04-2017 IPR020378 Protein of unknown function DUF4186 A4V04_RS00205 6ea3c16595fe367d966a6442a5998364 135 Pfam PF13811 Domain of unknown function (DUF4186) 6 113 2.1E-48 T 26-04-2017 IPR020378 Protein of unknown function DUF4186 A4V04_RS02575 5423d0dee89b44c7a29b5968fa9d80a7 267 SUPERFAMILY SSF56349 22 221 4.37E-21 T 26-04-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4V04_RS02575 5423d0dee89b44c7a29b5968fa9d80a7 267 Gene3D G3DSA:1.10.443.10 128 223 8.0E-15 T 26-04-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS02575 5423d0dee89b44c7a29b5968fa9d80a7 267 Pfam PF00589 Phage integrase family 128 212 1.5E-9 T 26-04-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS10560 388163eafef2d50c3ed23899598f3604 390 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 104 117 - T 26-04-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A4V04_RS10560 388163eafef2d50c3ed23899598f3604 390 Pfam PF00158 Sigma-54 interaction domain 82 246 3.5E-68 T 26-04-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A4V04_RS10560 388163eafef2d50c3ed23899598f3604 390 Gene3D G3DSA:1.10.8.60 253 324 4.9E-20 T 26-04-2017 A4V04_RS10560 388163eafef2d50c3ed23899598f3604 390 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 294 303 - T 26-04-2017 IPR025944 Sigma-54 interaction domain, conserved site A4V04_RS10560 388163eafef2d50c3ed23899598f3604 390 SMART SM00382 100 243 7.4E-10 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS10560 388163eafef2d50c3ed23899598f3604 390 Gene3D G3DSA:3.40.50.300 79 252 1.4E-54 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10560 388163eafef2d50c3ed23899598f3604 390 SUPERFAMILY SSF52540 83 322 4.22E-64 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03720 5aa460f0aee32cdbc1948ec20b948752 193 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 180 5.3E-32 T 26-04-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A4V04_RS03720 5aa460f0aee32cdbc1948ec20b948752 193 Gene3D G3DSA:3.40.920.10 2 183 9.1E-49 T 26-04-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A4V04_RS03720 5aa460f0aee32cdbc1948ec20b948752 193 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 2 183 5.1E-53 T 26-04-2017 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 A4V04_RS03720 5aa460f0aee32cdbc1948ec20b948752 193 SUPERFAMILY SSF53323 2 186 1.11E-41 T 26-04-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A4V04_RS09305 91ae1b95f42b4cdcb42fcca18e5331db 283 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 3 281 1.6E-82 T 26-04-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4V04_RS09305 91ae1b95f42b4cdcb42fcca18e5331db 283 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 283 35.478 T 26-04-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4V04_RS09305 91ae1b95f42b4cdcb42fcca18e5331db 283 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 26-04-2017 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4V04_RS09305 91ae1b95f42b4cdcb42fcca18e5331db 283 SUPERFAMILY SSF54506 3 282 1.02E-45 T 26-04-2017 A4V04_RS09305 91ae1b95f42b4cdcb42fcca18e5331db 283 Gene3D G3DSA:3.10.310.10 2 120 3.6E-50 T 26-04-2017 A4V04_RS09305 91ae1b95f42b4cdcb42fcca18e5331db 283 Pfam PF01678 Diaminopimelate epimerase 163 276 7.4E-25 T 26-04-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4V04_RS09305 91ae1b95f42b4cdcb42fcca18e5331db 283 Pfam PF01678 Diaminopimelate epimerase 5 124 4.1E-31 T 26-04-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4V04_RS09305 91ae1b95f42b4cdcb42fcca18e5331db 283 Gene3D G3DSA:3.10.310.10 121 269 4.5E-40 T 26-04-2017 A4V04_RS09910 59083b0e3229ef0bb2c446d201674995 230 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 223 2.6E-40 T 26-04-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A4V04_RS09910 59083b0e3229ef0bb2c446d201674995 230 Gene3D G3DSA:3.10.290.10 5 62 2.5E-4 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS09910 59083b0e3229ef0bb2c446d201674995 230 SUPERFAMILY SSF55174 5 67 2.85E-5 T 26-04-2017 A4V04_RS09910 59083b0e3229ef0bb2c446d201674995 230 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 26-04-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A4V04_RS09910 59083b0e3229ef0bb2c446d201674995 230 Pfam PF00849 RNA pseudouridylate synthase 62 193 8.9E-16 T 26-04-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS09910 59083b0e3229ef0bb2c446d201674995 230 SUPERFAMILY SSF55120 61 223 2.72E-38 T 26-04-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS07755 ba693aab67fb8368e9daf8c267bf860e 249 SUPERFAMILY SSF53850 22 247 5.16E-54 T 26-04-2017 A4V04_RS07755 ba693aab67fb8368e9daf8c267bf860e 249 Pfam PF13531 Bacterial extracellular solute-binding protein 23 247 1.5E-38 T 26-04-2017 A4V04_RS07755 ba693aab67fb8368e9daf8c267bf860e 249 Gene3D G3DSA:3.40.190.10 103 208 1.7E-32 T 26-04-2017 A4V04_RS07755 ba693aab67fb8368e9daf8c267bf860e 249 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 28 246 8.8E-64 T 26-04-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 A4V04_RS07755 ba693aab67fb8368e9daf8c267bf860e 249 PIRSF PIRSF004846 2 249 3.6E-48 T 26-04-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 A4V04_RS07755 ba693aab67fb8368e9daf8c267bf860e 249 Gene3D G3DSA:3.40.190.10 23 102 4.6E-9 T 26-04-2017 A4V04_RS08010 3d46d5745ca32136ced012b2f1ac178c 375 Pfam PF00149 Calcineurin-like phosphoesterase 151 316 3.8E-13 T 26-04-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4V04_RS08010 3d46d5745ca32136ced012b2f1ac178c 375 Gene3D G3DSA:3.60.21.10 151 325 2.7E-26 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS08010 3d46d5745ca32136ced012b2f1ac178c 375 SUPERFAMILY SSF56300 151 374 1.03E-35 T 26-04-2017 IPR029052 Metallo-dependent phosphatase-like A4V04_RS04690 90e9baff441ba36742acc4e5fead3a6e 371 Pfam PF12698 ABC-2 family transporter protein 31 363 3.9E-38 T 26-04-2017 A4V04_RS04690 90e9baff441ba36742acc4e5fead3a6e 371 PRINTS PR00164 ABC-2 type transport system membrane protein signature 294 313 2.2E-6 T 26-04-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4V04_RS04690 90e9baff441ba36742acc4e5fead3a6e 371 PRINTS PR00164 ABC-2 type transport system membrane protein signature 257 281 2.2E-6 T 26-04-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4V04_RS04690 90e9baff441ba36742acc4e5fead3a6e 371 PRINTS PR00164 ABC-2 type transport system membrane protein signature 314 333 2.2E-6 T 26-04-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4V04_RS06055 3c45dfb74b040beb464cb38907ef6622 508 SUPERFAMILY SSF52540 18 370 1.57E-53 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06055 3c45dfb74b040beb464cb38907ef6622 508 Gene3D G3DSA:3.40.50.300 26 113 1.2E-55 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06055 3c45dfb74b040beb464cb38907ef6622 508 Gene3D G3DSA:3.40.50.300 209 379 1.2E-55 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06055 3c45dfb74b040beb464cb38907ef6622 508 Pfam PF05872 Bacterial protein of unknown function (DUF853) 16 507 8.0E-228 T 26-04-2017 IPR033186 Helicase HerA-like C-terminal A4V04_RS10410 cd5713ed70334b677e4ff1c83e80f173 223 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 80 133 7.0E-11 T 26-04-2017 A4V04_RS10410 cd5713ed70334b677e4ff1c83e80f173 223 Hamap MF_00013 Octanoyltransferase [lipB]. 11 221 35.185 T 26-04-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4V04_RS10410 cd5713ed70334b677e4ff1c83e80f173 223 PIRSF PIRSF016262 7 223 2.2E-58 T 26-04-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4V04_RS10410 cd5713ed70334b677e4ff1c83e80f173 223 SUPERFAMILY SSF55681 9 217 1.16E-59 T 26-04-2017 A4V04_RS10410 cd5713ed70334b677e4ff1c83e80f173 223 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 37 200 2.6E-47 T 26-04-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4V04_RS10410 cd5713ed70334b677e4ff1c83e80f173 223 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 76 91 - T 26-04-2017 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A4V04_RS10410 cd5713ed70334b677e4ff1c83e80f173 223 Pfam PF03099 Biotin/lipoate A/B protein ligase family 61 172 9.8E-6 T 26-04-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 A4V04_RS10410 cd5713ed70334b677e4ff1c83e80f173 223 Gene3D G3DSA:3.90.1550.10 10 217 3.2E-64 T 26-04-2017 A4V04_RS04405 898f7f1ad906580538ad30a456b7b7df 301 SUPERFAMILY SSF103481 193 294 8.5E-9 T 26-04-2017 A4V04_RS04405 898f7f1ad906580538ad30a456b7b7df 301 SUPERFAMILY SSF103481 43 147 9.68E-12 T 26-04-2017 A4V04_RS04405 898f7f1ad906580538ad30a456b7b7df 301 Pfam PF00892 EamA-like transporter family 157 288 1.9E-15 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS04405 898f7f1ad906580538ad30a456b7b7df 301 Pfam PF00892 EamA-like transporter family 6 144 4.5E-15 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS01690 0a310a48cb4a4c6c2a8c09fe4f87b843 253 Gene3D G3DSA:3.30.70.20 55 97 1.3E-15 T 26-04-2017 A4V04_RS01690 0a310a48cb4a4c6c2a8c09fe4f87b843 253 Gene3D G3DSA:3.30.70.20 2 54 9.2E-37 T 26-04-2017 A4V04_RS01690 0a310a48cb4a4c6c2a8c09fe4f87b843 253 Gene3D G3DSA:3.30.70.20 194 246 9.2E-37 T 26-04-2017 A4V04_RS01690 0a310a48cb4a4c6c2a8c09fe4f87b843 253 Pfam PF12800 4Fe-4S binding domain 10 24 0.55 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS01690 0a310a48cb4a4c6c2a8c09fe4f87b843 253 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 94 105 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS01690 0a310a48cb4a4c6c2a8c09fe4f87b843 253 SUPERFAMILY SSF54862 180 247 2.2E-61 T 26-04-2017 A4V04_RS01690 0a310a48cb4a4c6c2a8c09fe4f87b843 253 SUPERFAMILY SSF54862 1 115 2.2E-61 T 26-04-2017 A4V04_RS01690 0a310a48cb4a4c6c2a8c09fe4f87b843 253 Gene3D G3DSA:3.30.70.20 167 193 2.3E-6 T 26-04-2017 A4V04_RS01690 0a310a48cb4a4c6c2a8c09fe4f87b843 253 Gene3D G3DSA:3.30.70.20 98 118 2.3E-6 T 26-04-2017 A4V04_RS01690 0a310a48cb4a4c6c2a8c09fe4f87b843 253 Pfam PF13247 4Fe-4S dicluster domain 176 213 8.8E-10 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS01690 0a310a48cb4a4c6c2a8c09fe4f87b843 253 Pfam PF13247 4Fe-4S dicluster domain 57 108 8.3E-11 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS05865 db512f1cd22573d4cd7184a5850ff8b1 775 Pfam PF07244 Surface antigen variable number repeat 94 173 1.2E-9 T 26-04-2017 IPR010827 Surface antigen variable number GO:0019867 A4V04_RS05865 db512f1cd22573d4cd7184a5850ff8b1 775 Pfam PF07244 Surface antigen variable number repeat 267 346 6.9E-9 T 26-04-2017 IPR010827 Surface antigen variable number GO:0019867 A4V04_RS05865 db512f1cd22573d4cd7184a5850ff8b1 775 Pfam PF07244 Surface antigen variable number repeat 177 264 5.5E-17 T 26-04-2017 IPR010827 Surface antigen variable number GO:0019867 A4V04_RS05865 db512f1cd22573d4cd7184a5850ff8b1 775 Pfam PF07244 Surface antigen variable number repeat 349 423 1.5E-12 T 26-04-2017 IPR010827 Surface antigen variable number GO:0019867 A4V04_RS05865 db512f1cd22573d4cd7184a5850ff8b1 775 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 26 775 1.2E-252 T 26-04-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 A4V04_RS05865 db512f1cd22573d4cd7184a5850ff8b1 775 Gene3D G3DSA:2.40.160.50 418 772 1.2E-25 T 26-04-2017 A4V04_RS05865 db512f1cd22573d4cd7184a5850ff8b1 775 Pfam PF01103 Surface antigen 450 775 2.3E-79 T 26-04-2017 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 A4V04_RS05865 db512f1cd22573d4cd7184a5850ff8b1 775 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 5 775 24.486 T 26-04-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 A4V04_RS05865 db512f1cd22573d4cd7184a5850ff8b1 775 PIRSF PIRSF006076 2 775 4.2E-246 T 26-04-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 A4V04_RS10825 3801bebaf497e717365a95d14bbf783f 177 Gene3D G3DSA:3.50.50.60 99 162 9.2E-12 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10825 3801bebaf497e717365a95d14bbf783f 177 SUPERFAMILY SSF56425 34 103 1.19E-18 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10825 3801bebaf497e717365a95d14bbf783f 177 Gene3D G3DSA:3.90.700.10 16 92 1.5E-20 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10825 3801bebaf497e717365a95d14bbf783f 177 Pfam PF00890 FAD binding domain 21 132 5.0E-17 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10825 3801bebaf497e717365a95d14bbf783f 177 SUPERFAMILY SSF51905 98 163 7.87E-5 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08210 f1a47b3d9542b01954be25742d75bae4 526 Gene3D G3DSA:3.90.700.10 307 449 4.2E-24 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08210 f1a47b3d9542b01954be25742d75bae4 526 SUPERFAMILY SSF51905 460 525 4.06E-38 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08210 f1a47b3d9542b01954be25742d75bae4 526 SUPERFAMILY SSF51905 20 279 4.06E-38 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08210 f1a47b3d9542b01954be25742d75bae4 526 Gene3D G3DSA:3.50.50.60 457 523 1.0E-62 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08210 f1a47b3d9542b01954be25742d75bae4 526 Gene3D G3DSA:3.50.50.60 28 273 1.0E-62 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08210 f1a47b3d9542b01954be25742d75bae4 526 Pfam PF00890 FAD binding domain 32 497 1.1E-47 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08210 f1a47b3d9542b01954be25742d75bae4 526 SUPERFAMILY SSF56425 308 461 2.02E-23 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS05490 321ce4a9d559b5718263227f042134cb 602 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 476 572 7.8E-9 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05490 321ce4a9d559b5718263227f042134cb 602 SUPERFAMILY SSF55874 467 581 4.85E-18 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05490 321ce4a9d559b5718263227f042134cb 602 SUPERFAMILY SSF53850 29 222 4.91E-18 T 26-04-2017 A4V04_RS05490 321ce4a9d559b5718263227f042134cb 602 Gene3D G3DSA:1.10.287.130 365 431 4.6E-4 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05490 321ce4a9d559b5718263227f042134cb 602 SMART SM00387 475 583 2.6E-8 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05490 321ce4a9d559b5718263227f042134cb 602 SUPERFAMILY SSF47384 362 434 1.29E-6 T 26-04-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4V04_RS05490 321ce4a9d559b5718263227f042134cb 602 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 35 263 4.3E-25 T 26-04-2017 A4V04_RS05490 321ce4a9d559b5718263227f042134cb 602 Gene3D G3DSA:3.40.190.10 121 229 1.8E-8 T 26-04-2017 A4V04_RS05490 321ce4a9d559b5718263227f042134cb 602 Gene3D G3DSA:3.30.565.10 461 577 9.7E-17 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS05485 f59770ae0508b56bffec10c08671bb18 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 2.4E-10 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS05485 f59770ae0508b56bffec10c08671bb18 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 2.4E-10 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS05485 f59770ae0508b56bffec10c08671bb18 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 2.4E-10 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS05485 f59770ae0508b56bffec10c08671bb18 213 Pfam PF00072 Response regulator receiver domain 7 115 5.3E-23 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS05485 f59770ae0508b56bffec10c08671bb18 213 SMART SM00448 4 115 2.9E-18 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS05485 f59770ae0508b56bffec10c08671bb18 213 SUPERFAMILY SSF52172 8 149 6.83E-30 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS05485 f59770ae0508b56bffec10c08671bb18 213 SUPERFAMILY SSF46894 131 199 3.37E-16 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS05485 f59770ae0508b56bffec10c08671bb18 213 SMART SM00421 139 196 1.1E-17 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS05485 f59770ae0508b56bffec10c08671bb18 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS05485 f59770ae0508b56bffec10c08671bb18 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 192 3.7E-16 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS05485 f59770ae0508b56bffec10c08671bb18 213 Gene3D G3DSA:1.10.10.10 148 193 3.7E-18 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS05485 f59770ae0508b56bffec10c08671bb18 213 Gene3D G3DSA:3.40.50.2300 6 147 2.1E-29 T 26-04-2017 A4V04_RS03815 7fe4204c4b3a947fbd682e7ba49395d7 178 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 18 174 35.586 T 26-04-2017 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 A4V04_RS03815 7fe4204c4b3a947fbd682e7ba49395d7 178 SUPERFAMILY SSF53155 17 98 5.49E-12 T 26-04-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS03815 7fe4204c4b3a947fbd682e7ba49395d7 178 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 94 172 1.7E-30 T 26-04-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS03815 7fe4204c4b3a947fbd682e7ba49395d7 178 Gene3D G3DSA:1.10.10.10 92 175 2.9E-34 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS03815 7fe4204c4b3a947fbd682e7ba49395d7 178 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 142 148 - T 26-04-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS03815 7fe4204c4b3a947fbd682e7ba49395d7 178 SUPERFAMILY SSF46767 92 172 2.09E-29 T 26-04-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS03815 7fe4204c4b3a947fbd682e7ba49395d7 178 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 93 171 2.4E-33 T 26-04-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS12355 63150ab0c2e1781e76aee26dc81a7709 231 Pfam PF07670 Nucleoside recognition 92 190 3.1E-6 T 26-04-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A4V04_RS05085 7900aceecf9e3382658cb5f749bd261b 230 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 224 1.6E-49 T 26-04-2017 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A4V04_RS05085 7900aceecf9e3382658cb5f749bd261b 230 SUPERFAMILY SSF53167 2 222 1.22E-62 T 26-04-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4V04_RS05085 7900aceecf9e3382658cb5f749bd261b 230 Pfam PF01048 Phosphorylase superfamily 2 222 4.1E-46 T 26-04-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4V04_RS05085 7900aceecf9e3382658cb5f749bd261b 230 Gene3D G3DSA:3.40.50.1580 1 228 9.8E-64 T 26-04-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4V04_RS06790 4c879dc88dad36a16a563eb8c2406469 586 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 562 571 - T 26-04-2017 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A4V04_RS06790 4c879dc88dad36a16a563eb8c2406469 586 Gene3D G3DSA:1.10.645.10 3 571 3.3E-222 T 26-04-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS06790 4c879dc88dad36a16a563eb8c2406469 586 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 41 66 - T 26-04-2017 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A4V04_RS06790 4c879dc88dad36a16a563eb8c2406469 586 Pfam PF00374 Nickel-dependent hydrogenase 41 571 2.1E-222 T 26-04-2017 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A4V04_RS06790 4c879dc88dad36a16a563eb8c2406469 586 SUPERFAMILY SSF56762 4 571 1.7E-173 T 26-04-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS08865 34a809890958dca8a666637254232770 326 Pfam PF00892 EamA-like transporter family 28 166 4.1E-14 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS08865 34a809890958dca8a666637254232770 326 Pfam PF00892 EamA-like transporter family 180 312 1.3E-12 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS08865 34a809890958dca8a666637254232770 326 SUPERFAMILY SSF103481 221 315 2.35E-7 T 26-04-2017 A4V04_RS08865 34a809890958dca8a666637254232770 326 SUPERFAMILY SSF103481 71 169 6.15E-7 T 26-04-2017 A4V04_RS13160 54fa2419eb289a762f953dc43014ba55 189 Gene3D G3DSA:3.40.80.10 6 177 8.0E-61 T 26-04-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4V04_RS13160 54fa2419eb289a762f953dc43014ba55 189 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 27 166 9.7E-18 T 26-04-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4V04_RS13160 54fa2419eb289a762f953dc43014ba55 189 SUPERFAMILY SSF55846 5 176 4.19E-55 T 26-04-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4V04_RS13160 54fa2419eb289a762f953dc43014ba55 189 SMART SM00644 17 165 1.0E-34 T 26-04-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4V04_RS07885 6eddb778788301b1967cec7b3c94c7e5 197 Gene3D G3DSA:3.40.30.10 2 188 4.1E-40 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS07885 6eddb778788301b1967cec7b3c94c7e5 197 SUPERFAMILY SSF52833 8 186 1.97E-32 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS07885 6eddb778788301b1967cec7b3c94c7e5 197 Pfam PF00578 AhpC/TSA family 53 166 6.8E-19 T 26-04-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4V04_RS10155 2afc1390e220f1f3bd1695274c880991 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 159 186 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10155 2afc1390e220f1f3bd1695274c880991 212 SUPERFAMILY SSF46894 139 203 5.1E-16 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS10155 2afc1390e220f1f3bd1695274c880991 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 1.4E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10155 2afc1390e220f1f3bd1695274c880991 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 1.4E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10155 2afc1390e220f1f3bd1695274c880991 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 1.4E-9 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10155 2afc1390e220f1f3bd1695274c880991 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 197 5.8E-12 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10155 2afc1390e220f1f3bd1695274c880991 212 SMART SM00448 7 118 1.2E-15 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS10155 2afc1390e220f1f3bd1695274c880991 212 SUPERFAMILY SSF52172 9 158 4.13E-27 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS10155 2afc1390e220f1f3bd1695274c880991 212 Pfam PF00072 Response regulator receiver domain 10 115 5.3E-20 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS10155 2afc1390e220f1f3bd1695274c880991 212 Gene3D G3DSA:3.40.50.2300 6 123 4.2E-24 T 26-04-2017 A4V04_RS10155 2afc1390e220f1f3bd1695274c880991 212 SMART SM00421 142 199 5.1E-14 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS10155 2afc1390e220f1f3bd1695274c880991 212 Gene3D G3DSA:1.10.10.10 142 201 2.3E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01195 bfe99a2f2f26a28b3b086974d90c89de 262 PIRSF PIRSF000094 1 260 3.3E-109 T 26-04-2017 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 A4V04_RS01195 bfe99a2f2f26a28b3b086974d90c89de 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 7.3E-85 T 26-04-2017 A4V04_RS01195 bfe99a2f2f26a28b3b086974d90c89de 262 Gene3D G3DSA:3.40.50.720 2 253 8.1E-63 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01195 bfe99a2f2f26a28b3b086974d90c89de 262 SUPERFAMILY SSF51735 5 255 1.42E-64 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01195 bfe99a2f2f26a28b3b086974d90c89de 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.1E-10 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS01195 bfe99a2f2f26a28b3b086974d90c89de 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.1E-10 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS01195 bfe99a2f2f26a28b3b086974d90c89de 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.1E-10 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS01195 bfe99a2f2f26a28b3b086974d90c89de 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.1E-10 T 26-04-2017 IPR002347 Short-chain dehydrogenase/reductase SDR A4V04_RS05680 494b03b2654de38783f8afa644bce6c3 239 ProSitePatterns PS01277 Ribonuclease PH signature. 120 132 - T 26-04-2017 IPR018336 Ribonuclease PH, conserved site A4V04_RS05680 494b03b2654de38783f8afa644bce6c3 239 SUPERFAMILY SSF54211 5 185 7.59E-47 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS05680 494b03b2654de38783f8afa644bce6c3 239 SUPERFAMILY SSF55666 156 238 3.01E-23 T 26-04-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4V04_RS05680 494b03b2654de38783f8afa644bce6c3 239 Pfam PF03725 3' exoribonuclease family, domain 2 162 228 1.4E-9 T 26-04-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4V04_RS05680 494b03b2654de38783f8afa644bce6c3 239 Pfam PF01138 3' exoribonuclease family, domain 1 14 144 2.1E-25 T 26-04-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4V04_RS05680 494b03b2654de38783f8afa644bce6c3 239 Gene3D G3DSA:3.30.230.70 9 238 5.6E-33 T 26-04-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4V04_RS05680 494b03b2654de38783f8afa644bce6c3 239 Hamap MF_00564 Ribonuclease PH [rph]. 5 239 44.801 T 26-04-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 A4V04_RS05680 494b03b2654de38783f8afa644bce6c3 239 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 6 238 5.1E-113 T 26-04-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 A4V04_RS06975 8629d6dbb1c306bec38f877e591728ef 770 Gene3D G3DSA:3.30.460.10 248 378 9.3E-40 T 26-04-2017 A4V04_RS06975 8629d6dbb1c306bec38f877e591728ef 770 Pfam PF04607 Region found in RelA / SpoT proteins 291 398 4.1E-29 T 26-04-2017 IPR007685 RelA/SpoT GO:0015969 A4V04_RS06975 8629d6dbb1c306bec38f877e591728ef 770 Pfam PF13291 ACT domain 677 753 3.1E-10 T 26-04-2017 IPR002912 ACT domain GO:0008152|GO:0016597 A4V04_RS06975 8629d6dbb1c306bec38f877e591728ef 770 Gene3D G3DSA:3.30.70.260 693 751 1.0E-4 T 26-04-2017 A4V04_RS06975 8629d6dbb1c306bec38f877e591728ef 770 SUPERFAMILY SSF81301 234 444 4.9E-52 T 26-04-2017 A4V04_RS06975 8629d6dbb1c306bec38f877e591728ef 770 Pfam PF13328 HD domain 79 228 2.5E-46 T 26-04-2017 IPR003607 HD/PDEase domain A4V04_RS06975 8629d6dbb1c306bec38f877e591728ef 770 SUPERFAMILY SSF109604 59 243 6.28E-67 T 26-04-2017 A4V04_RS06975 8629d6dbb1c306bec38f877e591728ef 770 SMART SM00954 291 398 6.6E-45 T 26-04-2017 IPR007685 RelA/SpoT GO:0015969 A4V04_RS06975 8629d6dbb1c306bec38f877e591728ef 770 Pfam PF02824 TGS domain 440 499 2.2E-18 T 26-04-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 A4V04_RS06975 8629d6dbb1c306bec38f877e591728ef 770 SMART SM00471 94 206 1.6E-7 T 26-04-2017 IPR003607 HD/PDEase domain A4V04_RS06975 8629d6dbb1c306bec38f877e591728ef 770 SUPERFAMILY SSF81271 427 499 9.97E-19 T 26-04-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A4V04_RS06975 8629d6dbb1c306bec38f877e591728ef 770 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 79 748 3.5E-214 T 26-04-2017 IPR004811 RelA/SpoT family GO:0015969 A4V04_RS06975 8629d6dbb1c306bec38f877e591728ef 770 Gene3D G3DSA:3.10.20.30 440 499 4.5E-19 T 26-04-2017 IPR012675 Beta-grasp domain A4V04_RS07900 5b0e837b3dab6e49e5f0677bd9fe3163 430 Pfam PF05048 Periplasmic copper-binding protein (NosD) 153 379 2.2E-48 T 26-04-2017 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain A4V04_RS07900 5b0e837b3dab6e49e5f0677bd9fe3163 430 SMART SM00710 165 186 1200.0 T 26-04-2017 IPR006626 Parallel beta-helix repeat A4V04_RS07900 5b0e837b3dab6e49e5f0677bd9fe3163 430 SMART SM00710 83 120 310.0 T 26-04-2017 IPR006626 Parallel beta-helix repeat A4V04_RS07900 5b0e837b3dab6e49e5f0677bd9fe3163 430 SMART SM00710 311 364 9300.0 T 26-04-2017 IPR006626 Parallel beta-helix repeat A4V04_RS07900 5b0e837b3dab6e49e5f0677bd9fe3163 430 SMART SM00710 288 309 3900.0 T 26-04-2017 IPR006626 Parallel beta-helix repeat A4V04_RS07900 5b0e837b3dab6e49e5f0677bd9fe3163 430 SMART SM00710 254 287 1100.0 T 26-04-2017 IPR006626 Parallel beta-helix repeat A4V04_RS07900 5b0e837b3dab6e49e5f0677bd9fe3163 430 SMART SM00710 135 164 83.0 T 26-04-2017 IPR006626 Parallel beta-helix repeat A4V04_RS07900 5b0e837b3dab6e49e5f0677bd9fe3163 430 SMART SM00710 231 253 2900.0 T 26-04-2017 IPR006626 Parallel beta-helix repeat A4V04_RS07900 5b0e837b3dab6e49e5f0677bd9fe3163 430 Gene3D G3DSA:2.160.20.10 18 368 2.2E-29 T 26-04-2017 IPR012334 Pectin lyase fold A4V04_RS07900 5b0e837b3dab6e49e5f0677bd9fe3163 430 TIGRFAM TIGR04247 NosD_copper_fam: nitrous oxide reductase family maturation protein NosD 30 416 1.8E-113 T 26-04-2017 IPR026464 Nitrous oxide reductase family maturation protein NosD A4V04_RS07900 5b0e837b3dab6e49e5f0677bd9fe3163 430 SMART SM00722 191 363 6.2E-4 T 26-04-2017 IPR006633 Carbohydrate-binding/sugar hydrolysis domain A4V04_RS07900 5b0e837b3dab6e49e5f0677bd9fe3163 430 SMART SM00722 37 185 48.0 T 26-04-2017 IPR006633 Carbohydrate-binding/sugar hydrolysis domain A4V04_RS07900 5b0e837b3dab6e49e5f0677bd9fe3163 430 SUPERFAMILY SSF51126 24 400 1.86E-53 T 26-04-2017 IPR011050 Pectin lyase fold/virulence factor A4V04_RS03015 4c5c49b58643a6bcd2242374f643117c 402 Gene3D G3DSA:3.10.290.10 42 91 3.5E-10 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS03015 4c5c49b58643a6bcd2242374f643117c 402 SUPERFAMILY SSF55120 102 342 3.08E-71 T 26-04-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS03015 4c5c49b58643a6bcd2242374f643117c 402 Pfam PF01479 S4 domain 42 89 8.4E-8 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS03015 4c5c49b58643a6bcd2242374f643117c 402 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 38 338 5.6E-89 T 26-04-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS03015 4c5c49b58643a6bcd2242374f643117c 402 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 160 174 - T 26-04-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS03015 4c5c49b58643a6bcd2242374f643117c 402 Pfam PF00849 RNA pseudouridylate synthase 118 272 6.1E-34 T 26-04-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS03015 4c5c49b58643a6bcd2242374f643117c 402 SMART SM00363 42 102 4.2E-6 T 26-04-2017 IPR002942 RNA-binding S4 domain GO:0003723 A4V04_RS03015 4c5c49b58643a6bcd2242374f643117c 402 SUPERFAMILY SSF55174 42 134 5.74E-12 T 26-04-2017 A4V04_RS00090 a3290dbf7251063b12e0e468e6963553 116 SUPERFAMILY SSF55298 11 116 6.6E-24 T 26-04-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4V04_RS00090 a3290dbf7251063b12e0e468e6963553 116 Gene3D G3DSA:3.30.1330.40 7 115 7.9E-20 T 26-04-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4V04_RS00090 a3290dbf7251063b12e0e468e6963553 116 Pfam PF01042 Endoribonuclease L-PSP 5 114 7.4E-18 T 26-04-2017 IPR006175 YjgF/YER057c/UK114 family A4V04_RS07510 54fc4c24d10cb206e0c0e44a068a95ad 355 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 259 270 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS07510 54fc4c24d10cb206e0c0e44a068a95ad 355 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 52 63 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS07510 54fc4c24d10cb206e0c0e44a068a95ad 355 SUPERFAMILY SSF54862 243 311 2.36E-17 T 26-04-2017 A4V04_RS07510 54fc4c24d10cb206e0c0e44a068a95ad 355 Gene3D G3DSA:3.30.70.20 57 137 9.4E-5 T 26-04-2017 A4V04_RS07510 54fc4c24d10cb206e0c0e44a068a95ad 355 SUPERFAMILY SSF54862 25 71 7.18E-11 T 26-04-2017 A4V04_RS07510 54fc4c24d10cb206e0c0e44a068a95ad 355 Pfam PF00037 4Fe-4S binding domain 252 274 1.6E-7 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07510 54fc4c24d10cb206e0c0e44a068a95ad 355 Gene3D G3DSA:3.30.70.20 25 56 9.9E-11 T 26-04-2017 A4V04_RS07510 54fc4c24d10cb206e0c0e44a068a95ad 355 Gene3D G3DSA:3.30.70.20 235 266 2.6E-8 T 26-04-2017 A4V04_RS07510 54fc4c24d10cb206e0c0e44a068a95ad 355 Gene3D G3DSA:3.30.70.20 138 145 2.6E-8 T 26-04-2017 A4V04_RS07510 54fc4c24d10cb206e0c0e44a068a95ad 355 Gene3D G3DSA:3.30.70.20 267 313 1.6E-12 T 26-04-2017 A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 Gene3D G3DSA:1.25.40.10 117 184 1.9E-16 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 Gene3D G3DSA:1.25.40.10 285 394 7.9E-25 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 Gene3D G3DSA:1.25.40.10 185 284 1.5E-19 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 Pfam PF08238 Sel1 repeat 189 223 1.3E-6 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 Pfam PF08238 Sel1 repeat 125 151 0.011 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 Pfam PF08238 Sel1 repeat 300 326 0.46 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 Pfam PF08238 Sel1 repeat 329 359 0.005 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 Pfam PF08238 Sel1 repeat 264 294 2.4E-4 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 Pfam PF08238 Sel1 repeat 153 186 0.27 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 SUPERFAMILY SSF81901 118 305 3.35E-34 T 26-04-2017 A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 SUPERFAMILY SSF81901 273 395 6.28E-20 T 26-04-2017 A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 SMART SM00671 152 187 0.0043 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 SMART SM00671 260 295 3.7E-4 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 SMART SM00671 328 364 0.01 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 SMART SM00671 296 327 0.011 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 SMART SM00671 188 223 7.2E-8 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04570 3468e0686bd189174fd593ecc3069df6 517 SMART SM00671 119 151 2.5 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS07040 686650b044909b7f3f44fafc6f415088 420 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 416 1.5E-207 T 26-04-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A4V04_RS07040 686650b044909b7f3f44fafc6f415088 420 SUPERFAMILY SSF68912 1 46 1.22E-12 T 26-04-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 A4V04_RS07040 686650b044909b7f3f44fafc6f415088 420 Gene3D G3DSA:1.10.720.10 1 47 6.1E-22 T 26-04-2017 A4V04_RS07040 686650b044909b7f3f44fafc6f415088 420 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 2.0E-17 T 26-04-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 A4V04_RS07040 686650b044909b7f3f44fafc6f415088 420 SMART SM00357 52 118 6.1E-18 T 26-04-2017 IPR011129 Cold shock protein GO:0003676 A4V04_RS07040 686650b044909b7f3f44fafc6f415088 420 SMART SM00959 5 47 1.9E-18 T 26-04-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 A4V04_RS07040 686650b044909b7f3f44fafc6f415088 420 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 420 242.173 T 26-04-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A4V04_RS07040 686650b044909b7f3f44fafc6f415088 420 Gene3D G3DSA:2.40.50.140 49 117 5.6E-34 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS07040 686650b044909b7f3f44fafc6f415088 420 SMART SM00382 170 349 2.6E-8 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS07040 686650b044909b7f3f44fafc6f415088 420 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 3.1E-31 T 26-04-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 A4V04_RS07040 686650b044909b7f3f44fafc6f415088 420 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 1.4E-23 T 26-04-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4V04_RS07040 686650b044909b7f3f44fafc6f415088 420 SUPERFAMILY SSF50249 49 125 1.6E-28 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS07040 686650b044909b7f3f44fafc6f415088 420 Gene3D G3DSA:3.40.50.300 131 416 5.7E-104 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07040 686650b044909b7f3f44fafc6f415088 420 SUPERFAMILY SSF52540 90 371 4.41E-67 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03325 46273cade8417a5c76563919ecb6b41a 255 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 22 215 2.3E-55 T 26-04-2017 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein A4V04_RS03325 46273cade8417a5c76563919ecb6b41a 255 SUPERFAMILY SSF102114 40 224 2.49E-25 T 26-04-2017 A4V04_RS03325 46273cade8417a5c76563919ecb6b41a 255 Gene3D G3DSA:3.20.20.70 40 241 6.0E-24 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS03325 46273cade8417a5c76563919ecb6b41a 255 Pfam PF04055 Radical SAM superfamily 40 191 6.7E-18 T 26-04-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 A4V04_RS03325 46273cade8417a5c76563919ecb6b41a 255 Pfam PF13353 4Fe-4S single cluster domain 37 122 1.1E-9 T 26-04-2017 A4V04_RS08075 6c36803b7aaa06b4b67ad089809c7b62 548 Pfam PF02384 N-6 DNA Methylase 243 350 2.4E-10 T 26-04-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A4V04_RS08075 6c36803b7aaa06b4b67ad089809c7b62 548 Gene3D G3DSA:3.40.50.150 238 308 2.1E-4 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS08075 6c36803b7aaa06b4b67ad089809c7b62 548 SUPERFAMILY SSF116734 363 544 9.81E-14 T 26-04-2017 A4V04_RS08075 6c36803b7aaa06b4b67ad089809c7b62 548 SUPERFAMILY SSF53335 244 353 1.77E-12 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS08075 6c36803b7aaa06b4b67ad089809c7b62 548 Pfam PF01420 Type I restriction modification DNA specificity domain 363 543 2.9E-6 T 26-04-2017 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A4V04_RS07445 e9a7238eefd7e395f532cb4a49c23286 255 Gene3D G3DSA:3.40.190.10 113 209 3.7E-17 T 26-04-2017 A4V04_RS07445 e9a7238eefd7e395f532cb4a49c23286 255 SUPERFAMILY SSF53850 4 247 6.42E-64 T 26-04-2017 A4V04_RS07445 e9a7238eefd7e395f532cb4a49c23286 255 Gene3D G3DSA:3.40.190.10 25 112 7.2E-45 T 26-04-2017 A4V04_RS07445 e9a7238eefd7e395f532cb4a49c23286 255 Gene3D G3DSA:3.40.190.10 210 249 7.2E-45 T 26-04-2017 A4V04_RS07445 e9a7238eefd7e395f532cb4a49c23286 255 SMART SM00079 26 248 1.1E-5 T 26-04-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A4V04_RS07445 e9a7238eefd7e395f532cb4a49c23286 255 SMART SM00062 26 249 2.1E-60 T 26-04-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4V04_RS07445 e9a7238eefd7e395f532cb4a49c23286 255 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 247 4.8E-64 T 26-04-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 7 430 40.117 T 26-04-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 Gene3D G3DSA:3.40.50.1980 30 242 2.5E-80 T 26-04-2017 A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 PIRSF PIRSF000099 1 433 2.8E-158 T 26-04-2017 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 PRINTS PR00083 Histidinol dehydrogenase signature 139 165 6.0E-83 T 26-04-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 PRINTS PR00083 Histidinol dehydrogenase signature 173 199 6.0E-83 T 26-04-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 PRINTS PR00083 Histidinol dehydrogenase signature 203 228 6.0E-83 T 26-04-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 PRINTS PR00083 Histidinol dehydrogenase signature 232 253 6.0E-83 T 26-04-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 PRINTS PR00083 Histidinol dehydrogenase signature 35 59 6.0E-83 T 26-04-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 PRINTS PR00083 Histidinol dehydrogenase signature 323 348 6.0E-83 T 26-04-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 PRINTS PR00083 Histidinol dehydrogenase signature 364 382 6.0E-83 T 26-04-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 PRINTS PR00083 Histidinol dehydrogenase signature 254 273 6.0E-83 T 26-04-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 SUPERFAMILY SSF53720 29 430 1.39E-84 T 26-04-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 Pfam PF00815 Histidinol dehydrogenase 29 429 2.3E-164 T 26-04-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 36 429 2.4E-159 T 26-04-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4V04_RS12610 7681d5e33c84c3ee92828337e0c20a46 438 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 232 264 - T 26-04-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 A4V04_RS02400 d53d40dc1b3ff1ddab05e659722b3a3f 98 SUPERFAMILY SSF47413 33 93 9.09E-7 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS02400 d53d40dc1b3ff1ddab05e659722b3a3f 98 Gene3D G3DSA:1.10.260.40 40 93 7.7E-4 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS02400 d53d40dc1b3ff1ddab05e659722b3a3f 98 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 16 92 5.9E-16 T 26-04-2017 IPR014057 Addiction module antidote protein, HI1420 A4V04_RS01750 de5784a1ae347ac8c6f57c598d00b28c 141 Pfam PF15970 HicB_like antitoxin of bacterial toxin-antitoxin system 7 82 3.0E-9 T 26-04-2017 IPR032753 HicB-like antitoxin A4V04_RS01750 de5784a1ae347ac8c6f57c598d00b28c 141 SUPERFAMILY SSF143100 4 66 6.28E-10 T 26-04-2017 A4V04_RS11225 ec355d650aefdfb5498d5dda5861d371 216 SUPERFAMILY SSF50447 5 214 4.77E-77 T 26-04-2017 IPR009000 Translation protein, beta-barrel domain A4V04_RS11225 ec355d650aefdfb5498d5dda5861d371 216 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 6 209 3.7E-84 T 26-04-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11225 ec355d650aefdfb5498d5dda5861d371 216 ProSitePatterns PS00474 Ribosomal protein L3 signature. 106 129 - T 26-04-2017 IPR019926 Ribosomal protein L3, conserved site A4V04_RS11225 ec355d650aefdfb5498d5dda5861d371 216 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 4 212 37.672 T 26-04-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11225 ec355d650aefdfb5498d5dda5861d371 216 Pfam PF00297 Ribosomal protein L3 68 187 4.0E-15 T 26-04-2017 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11225 ec355d650aefdfb5498d5dda5861d371 216 Gene3D G3DSA:2.40.30.10 163 214 3.1E-8 T 26-04-2017 A4V04_RS11225 ec355d650aefdfb5498d5dda5861d371 216 Gene3D G3DSA:2.40.30.10 6 35 3.1E-8 T 26-04-2017 A4V04_RS11225 ec355d650aefdfb5498d5dda5861d371 216 Gene3D G3DSA:4.10.960.10 83 162 9.4E-27 T 26-04-2017 A4V04_RS13130 304b863f0a5c70f8e6d4655faa434947 345 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 345 166.614 T 26-04-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A4V04_RS13130 304b863f0a5c70f8e6d4655faa434947 345 SUPERFAMILY SSF46785 260 332 5.69E-23 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS13130 304b863f0a5c70f8e6d4655faa434947 345 Gene3D G3DSA:1.10.10.10 261 331 1.5E-31 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS13130 304b863f0a5c70f8e6d4655faa434947 345 SUPERFAMILY SSF52540 24 255 2.2E-51 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13130 304b863f0a5c70f8e6d4655faa434947 345 Gene3D G3DSA:3.40.50.300 24 180 2.8E-32 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13130 304b863f0a5c70f8e6d4655faa434947 345 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 28 330 2.6E-141 T 26-04-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A4V04_RS13130 304b863f0a5c70f8e6d4655faa434947 345 SMART SM00382 55 188 5.3E-11 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS13130 304b863f0a5c70f8e6d4655faa434947 345 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 8 239 7.0E-115 T 26-04-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 A4V04_RS13130 304b863f0a5c70f8e6d4655faa434947 345 Gene3D G3DSA:1.10.8.60 188 258 1.5E-30 T 26-04-2017 A4V04_RS13130 304b863f0a5c70f8e6d4655faa434947 345 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 254 331 3.0E-25 T 26-04-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A4V04_RS13130 304b863f0a5c70f8e6d4655faa434947 345 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 257 330 9.6E-31 T 26-04-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A4V04_RS03980 9f1be19134697bee5578f9409846c0b0 597 Gene3D G3DSA:3.90.700.10 386 530 6.5E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03980 9f1be19134697bee5578f9409846c0b0 597 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 136 590 2.1E-114 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS03980 9f1be19134697bee5578f9409846c0b0 597 Pfam PF00890 FAD binding domain 137 578 4.7E-79 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03980 9f1be19134697bee5578f9409846c0b0 597 SMART SM00900 35 109 2.5E-12 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS03980 9f1be19134697bee5578f9409846c0b0 597 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 543 565 2.4E-5 T 26-04-2017 A4V04_RS03980 9f1be19134697bee5578f9409846c0b0 597 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 156 2.4E-5 T 26-04-2017 A4V04_RS03980 9f1be19134697bee5578f9409846c0b0 597 Gene3D G3DSA:3.50.50.60 531 596 1.2E-89 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03980 9f1be19134697bee5578f9409846c0b0 597 Gene3D G3DSA:3.50.50.60 131 385 1.2E-89 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03980 9f1be19134697bee5578f9409846c0b0 597 SUPERFAMILY SSF51905 127 395 1.89E-57 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03980 9f1be19134697bee5578f9409846c0b0 597 SUPERFAMILY SSF51905 538 595 1.89E-57 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03980 9f1be19134697bee5578f9409846c0b0 597 SUPERFAMILY SSF56425 384 539 2.39E-29 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS03980 9f1be19134697bee5578f9409846c0b0 597 Pfam PF04205 FMN-binding domain 35 107 3.4E-11 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS10520 73f676210af568fa642d45d9a822e200 116 SUPERFAMILY SSF48695 10 109 9.48E-13 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS10520 73f676210af568fa642d45d9a822e200 116 Gene3D G3DSA:3.90.10.10 4 112 2.7E-12 T 26-04-2017 A4V04_RS10520 73f676210af568fa642d45d9a822e200 116 Pfam PF14537 Cytochrome c3 34 109 1.0E-13 T 26-04-2017 A4V04_RS11335 16dd51056d08ce1ea816429a68f60640 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.7E-29 T 26-04-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11335 16dd51056d08ce1ea816429a68f60640 121 SUPERFAMILY SSF46946 2 114 9.42E-43 T 26-04-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4V04_RS11335 16dd51056d08ce1ea816429a68f60640 121 Gene3D G3DSA:1.10.8.50 1 71 1.0E-28 T 26-04-2017 A4V04_RS11335 16dd51056d08ce1ea816429a68f60640 121 PIRSF PIRSF002134 1 121 3.4E-40 T 26-04-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11335 16dd51056d08ce1ea816429a68f60640 121 Gene3D G3DSA:4.10.910.10 72 119 2.1E-23 T 26-04-2017 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11335 16dd51056d08ce1ea816429a68f60640 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 26.576 T 26-04-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11335 16dd51056d08ce1ea816429a68f60640 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 1.5E-50 T 26-04-2017 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS06800 50d0474448abb3fef7f0ad36052664e1 116 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 29 103 2.0E-27 T 26-04-2017 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 A4V04_RS06800 50d0474448abb3fef7f0ad36052664e1 116 Pfam PF01381 Helix-turn-helix 43 91 3.0E-11 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS06800 50d0474448abb3fef7f0ad36052664e1 116 Gene3D G3DSA:1.10.260.40 29 103 1.1E-29 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS06800 50d0474448abb3fef7f0ad36052664e1 116 SMART SM00530 23 92 7.4E-9 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS06800 50d0474448abb3fef7f0ad36052664e1 116 SUPERFAMILY SSF47413 32 108 3.75E-23 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS04245 eff8459c8b0a22c36b8a24cd2bc1bb14 283 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 80 88 - T 26-04-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4V04_RS04245 eff8459c8b0a22c36b8a24cd2bc1bb14 283 SUPERFAMILY SSF54292 26 127 2.1E-25 T 26-04-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4V04_RS04245 eff8459c8b0a22c36b8a24cd2bc1bb14 283 Gene3D G3DSA:3.10.20.30 21 127 6.3E-32 T 26-04-2017 IPR012675 Beta-grasp domain A4V04_RS04245 eff8459c8b0a22c36b8a24cd2bc1bb14 283 Pfam PF13183 4Fe-4S dicluster domain 171 244 1.1E-8 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS04245 eff8459c8b0a22c36b8a24cd2bc1bb14 283 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 32 254 8.4E-52 T 26-04-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04245 eff8459c8b0a22c36b8a24cd2bc1bb14 283 Gene3D G3DSA:1.10.1060.10 136 262 1.2E-27 T 26-04-2017 A4V04_RS04245 eff8459c8b0a22c36b8a24cd2bc1bb14 283 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 174 185 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS04245 eff8459c8b0a22c36b8a24cd2bc1bb14 283 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 30 132 4.4E-28 T 26-04-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS04245 eff8459c8b0a22c36b8a24cd2bc1bb14 283 SUPERFAMILY SSF46548 132 261 7.32E-24 T 26-04-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 A4V04_RS09180 474a6b9ee4ca0ca4cbde8b5d6e7e62c5 89 Gene3D G3DSA:2.10.260.10 1 88 2.9E-10 T 26-04-2017 A4V04_RS09180 474a6b9ee4ca0ca4cbde8b5d6e7e62c5 89 SUPERFAMILY SSF89447 4 65 2.96E-6 T 26-04-2017 A4V04_RS01945 02def29fdc724c64afa854062bb3ab8a 267 Pfam PF01061 ABC-2 type transporter 27 225 3.4E-22 T 26-04-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4V04_RS02150 a7667201f73915e7c929e2d5bf2b359a 202 Pfam PF00072 Response regulator receiver domain 11 120 4.9E-22 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS02150 a7667201f73915e7c929e2d5bf2b359a 202 SMART SM00448 9 120 2.0E-22 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS02150 a7667201f73915e7c929e2d5bf2b359a 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 191 7.4E-17 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02150 a7667201f73915e7c929e2d5bf2b359a 202 Gene3D G3DSA:1.10.10.10 146 191 1.4E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02150 a7667201f73915e7c929e2d5bf2b359a 202 SUPERFAMILY SSF52172 8 165 6.26E-29 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS02150 a7667201f73915e7c929e2d5bf2b359a 202 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02150 a7667201f73915e7c929e2d5bf2b359a 202 Gene3D G3DSA:3.40.50.2300 8 145 2.2E-27 T 26-04-2017 A4V04_RS02150 a7667201f73915e7c929e2d5bf2b359a 202 SMART SM00421 143 200 4.7E-15 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02150 a7667201f73915e7c929e2d5bf2b359a 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 8.0E-13 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02150 a7667201f73915e7c929e2d5bf2b359a 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 8.0E-13 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS02150 a7667201f73915e7c929e2d5bf2b359a 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 8.0E-13 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS11925 6f2405d29307ed34eee2c68f976448ae 179 Gene3D G3DSA:2.20.28.10 135 178 1.0E-16 T 26-04-2017 IPR004039 Rubredoxin-type fold A4V04_RS11925 6f2405d29307ed34eee2c68f976448ae 179 Pfam PF02915 Rubrerythrin 12 127 8.5E-23 T 26-04-2017 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A4V04_RS11925 6f2405d29307ed34eee2c68f976448ae 179 SUPERFAMILY SSF47240 5 134 3.68E-41 T 26-04-2017 IPR009078 Ferritin-like superfamily A4V04_RS11925 6f2405d29307ed34eee2c68f976448ae 179 SUPERFAMILY SSF57802 136 178 5.14E-11 T 26-04-2017 A4V04_RS11925 6f2405d29307ed34eee2c68f976448ae 179 Gene3D G3DSA:1.20.1260.10 3 132 1.2E-53 T 26-04-2017 IPR012347 Ferritin-related A4V04_RS12455 622965910dce364c42387c18f91cf1a6 194 SUPERFAMILY SSF50475 26 183 2.14E-34 T 26-04-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4V04_RS12455 622965910dce364c42387c18f91cf1a6 194 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 41 181 1.2E-16 T 26-04-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related A4V04_RS12455 622965910dce364c42387c18f91cf1a6 194 Gene3D G3DSA:2.30.110.10 30 185 5.9E-37 T 26-04-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4V04_RS01320 2b34eae16433f4a144f1777c708d6957 256 SUPERFAMILY SSF102215 1 253 5.1E-57 T 26-04-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 A4V04_RS01320 2b34eae16433f4a144f1777c708d6957 256 Pfam PF02633 Creatinine amidohydrolase 9 249 1.7E-56 T 26-04-2017 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 A4V04_RS01320 2b34eae16433f4a144f1777c708d6957 256 Gene3D G3DSA:3.40.50.10310 2 254 7.8E-65 T 26-04-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 A4V04_RS08955 634cbd46baff02eb871330162dbbbcb3 110 SUPERFAMILY SSF48695 24 107 2.42E-13 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS08955 634cbd46baff02eb871330162dbbbcb3 110 Pfam PF14537 Cytochrome c3 29 107 3.2E-16 T 26-04-2017 A4V04_RS08955 634cbd46baff02eb871330162dbbbcb3 110 Gene3D G3DSA:3.90.10.10 25 107 1.6E-11 T 26-04-2017 A4V04_RS04450 777bb6f87de58c2619050a00cc653122 256 SUPERFAMILY SSF81342 4 223 4.87E-19 T 26-04-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A4V04_RS04450 777bb6f87de58c2619050a00cc653122 256 Gene3D G3DSA:1.20.950.20 3 229 2.4E-29 T 26-04-2017 A4V04_RS04450 777bb6f87de58c2619050a00cc653122 256 Pfam PF01292 Prokaryotic cytochrome b561 8 188 4.1E-16 T 26-04-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 A4V04_RS07495 db3c7aa1ff9c0c2d6d8f3e61e6521acf 241 Gene3D G3DSA:3.40.50.1000 84 227 4.3E-40 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS07495 db3c7aa1ff9c0c2d6d8f3e61e6521acf 241 Gene3D G3DSA:1.20.1440.100 18 83 1.5E-15 T 26-04-2017 A4V04_RS07495 db3c7aa1ff9c0c2d6d8f3e61e6521acf 241 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 7 193 1.0E-21 T 26-04-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 A4V04_RS07495 db3c7aa1ff9c0c2d6d8f3e61e6521acf 241 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 7 209 5.1E-36 T 26-04-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial A4V04_RS07495 db3c7aa1ff9c0c2d6d8f3e61e6521acf 241 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 192 7.9E-34 T 26-04-2017 A4V04_RS07495 db3c7aa1ff9c0c2d6d8f3e61e6521acf 241 SUPERFAMILY SSF56784 7 218 4.46E-30 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS08490 41e980bca227fe66d9d6a23fe5592e17 131 SUPERFAMILY SSF101738 8 112 1.83E-30 T 26-04-2017 IPR007481 Stringent starvation protein B A4V04_RS08490 41e980bca227fe66d9d6a23fe5592e17 131 Pfam PF04386 Stringent starvation protein B 12 109 1.5E-20 T 26-04-2017 IPR007481 Stringent starvation protein B A4V04_RS08490 41e980bca227fe66d9d6a23fe5592e17 131 Gene3D G3DSA:2.30.30.220 10 106 1.3E-30 T 26-04-2017 IPR007481 Stringent starvation protein B A4V04_RS00280 9f1384695b0508def5096ff3a53dd2b1 371 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 7 367 1.9E-107 T 26-04-2017 IPR017687 Outer membrane protein assembly factor BamB A4V04_RS00280 9f1384695b0508def5096ff3a53dd2b1 371 Gene3D G3DSA:2.140.10.10 1 347 4.3E-59 T 26-04-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain A4V04_RS00280 9f1384695b0508def5096ff3a53dd2b1 371 Pfam PF13360 PQQ-like domain 69 297 2.5E-45 T 26-04-2017 IPR002372 Pyrrolo-quinoline quinone repeat A4V04_RS00280 9f1384695b0508def5096ff3a53dd2b1 371 SUPERFAMILY SSF50998 24 345 4.71E-64 T 26-04-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4V04_RS00280 9f1384695b0508def5096ff3a53dd2b1 371 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 2 370 29.547 T 26-04-2017 IPR017687 Outer membrane protein assembly factor BamB A4V04_RS00280 9f1384695b0508def5096ff3a53dd2b1 371 SMART SM00564 94 125 430.0 T 26-04-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4V04_RS00280 9f1384695b0508def5096ff3a53dd2b1 371 SMART SM00564 230 261 10.0 T 26-04-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4V04_RS00280 9f1384695b0508def5096ff3a53dd2b1 371 SMART SM00564 178 210 290.0 T 26-04-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4V04_RS00280 9f1384695b0508def5096ff3a53dd2b1 371 SMART SM00564 55 86 500.0 T 26-04-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4V04_RS00280 9f1384695b0508def5096ff3a53dd2b1 371 SMART SM00564 309 340 0.13 T 26-04-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4V04_RS00280 9f1384695b0508def5096ff3a53dd2b1 371 SMART SM00564 134 165 0.13 T 26-04-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4V04_RS00280 9f1384695b0508def5096ff3a53dd2b1 371 SMART SM00564 268 299 3.5 T 26-04-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4V04_RS02890 a8e80dd420224489e890bc80a1de629d 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 77 8.7E-33 T 26-04-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS02890 a8e80dd420224489e890bc80a1de629d 79 Gene3D G3DSA:1.10.1200.10 3 76 2.9E-31 T 26-04-2017 IPR009081 Phosphopantetheine binding ACP domain A4V04_RS02890 a8e80dd420224489e890bc80a1de629d 79 SMART SM00823 Phosphopantetheine attachment site 5 61 0.0047 T 26-04-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4V04_RS02890 a8e80dd420224489e890bc80a1de629d 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 26-04-2017 IPR006162 Phosphopantetheine attachment site A4V04_RS02890 a8e80dd420224489e890bc80a1de629d 79 SUPERFAMILY SSF47336 2 76 9.95E-23 T 26-04-2017 IPR009081 Phosphopantetheine binding ACP domain A4V04_RS02890 a8e80dd420224489e890bc80a1de629d 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 6.8E-16 T 26-04-2017 IPR009081 Phosphopantetheine binding ACP domain A4V04_RS02890 a8e80dd420224489e890bc80a1de629d 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 21.314 T 26-04-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS02890 a8e80dd420224489e890bc80a1de629d 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 34 74 2.0E-9 T 26-04-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS01915 6cce688082ff24dc2d01cb6b080c96e5 611 Pfam PF01609 Transposase DDE domain 219 509 1.1E-6 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS12635 91dacacbb6d1f55d4292da23b2ae718a 762 PRINTS PR01440 Cellulose synthase subunit B signature 179 200 3.0E-30 T 26-04-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 A4V04_RS12635 91dacacbb6d1f55d4292da23b2ae718a 762 PRINTS PR01440 Cellulose synthase subunit B signature 303 324 3.0E-30 T 26-04-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 A4V04_RS12635 91dacacbb6d1f55d4292da23b2ae718a 762 PRINTS PR01440 Cellulose synthase subunit B signature 386 407 3.0E-30 T 26-04-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 A4V04_RS12635 91dacacbb6d1f55d4292da23b2ae718a 762 PRINTS PR01440 Cellulose synthase subunit B signature 89 110 3.0E-30 T 26-04-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 A4V04_RS12635 91dacacbb6d1f55d4292da23b2ae718a 762 PRINTS PR01440 Cellulose synthase subunit B signature 556 576 3.0E-30 T 26-04-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 A4V04_RS12635 91dacacbb6d1f55d4292da23b2ae718a 762 PRINTS PR01440 Cellulose synthase subunit B signature 519 538 3.0E-30 T 26-04-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 A4V04_RS12635 91dacacbb6d1f55d4292da23b2ae718a 762 PRINTS PR01440 Cellulose synthase subunit B signature 221 244 3.0E-30 T 26-04-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 A4V04_RS12635 91dacacbb6d1f55d4292da23b2ae718a 762 PRINTS PR01440 Cellulose synthase subunit B signature 703 723 3.0E-30 T 26-04-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 A4V04_RS12635 91dacacbb6d1f55d4292da23b2ae718a 762 Pfam PF03170 Bacterial cellulose synthase subunit 73 663 6.2E-169 T 26-04-2017 IPR018513 Cellulose synthase BcsB, bacterial GO:0006011|GO:0016020 A4V04_RS07960 5fdfe32e55bc4c9d83877ba8ee1b2159 216 SUPERFAMILY SSF52374 2 209 3.26E-39 T 26-04-2017 A4V04_RS07960 5fdfe32e55bc4c9d83877ba8ee1b2159 216 Pfam PF01467 Cytidylyltransferase-like 5 178 1.7E-23 T 26-04-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4V04_RS07960 5fdfe32e55bc4c9d83877ba8ee1b2159 216 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 208 24.869 T 26-04-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 A4V04_RS07960 5fdfe32e55bc4c9d83877ba8ee1b2159 216 Gene3D G3DSA:3.40.50.620 1 208 2.1E-49 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS07960 5fdfe32e55bc4c9d83877ba8ee1b2159 216 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 5 207 1.2E-39 T 26-04-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 A4V04_RS09290 36e557de8954667e205315a35fff77ed 427 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 13 408 7.2E-81 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS09290 36e557de8954667e205315a35fff77ed 427 Gene3D G3DSA:3.30.70.360 224 329 1.4E-23 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS09290 36e557de8954667e205315a35fff77ed 427 Pfam PF07687 Peptidase dimerisation domain 226 304 4.1E-7 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS09290 36e557de8954667e205315a35fff77ed 427 PIRSF PIRSF005962 1 427 4.1E-101 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS09290 36e557de8954667e205315a35fff77ed 427 SUPERFAMILY SSF53187 89 237 4.63E-53 T 26-04-2017 A4V04_RS09290 36e557de8954667e205315a35fff77ed 427 SUPERFAMILY SSF53187 336 422 4.63E-53 T 26-04-2017 A4V04_RS09290 36e557de8954667e205315a35fff77ed 427 SUPERFAMILY SSF53187 8 51 4.63E-53 T 26-04-2017 A4V04_RS09290 36e557de8954667e205315a35fff77ed 427 SUPERFAMILY SSF55031 222 330 1.22E-19 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS09290 36e557de8954667e205315a35fff77ed 427 Pfam PF01546 Peptidase family M20/M25/M40 107 421 6.6E-18 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS09290 36e557de8954667e205315a35fff77ed 427 Gene3D G3DSA:3.40.630.10 333 424 3.7E-65 T 26-04-2017 A4V04_RS09290 36e557de8954667e205315a35fff77ed 427 Gene3D G3DSA:3.40.630.10 89 219 3.7E-65 T 26-04-2017 A4V04_RS09290 36e557de8954667e205315a35fff77ed 427 Gene3D G3DSA:3.40.630.10 10 51 3.7E-65 T 26-04-2017 A4V04_RS03360 c3cd291d61968fd6e9bf3ea39be62549 198 PIRSF PIRSF000847 7 198 5.4E-43 T 26-04-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 A4V04_RS03360 c3cd291d61968fd6e9bf3ea39be62549 198 Pfam PF01066 CDP-alcohol phosphatidyltransferase 11 83 3.6E-16 T 26-04-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4V04_RS03360 c3cd291d61968fd6e9bf3ea39be62549 198 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 10 187 7.3E-51 T 26-04-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 A4V04_RS03360 c3cd291d61968fd6e9bf3ea39be62549 198 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 61 83 - T 26-04-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4V04_RS01360 86483bf44bd2fff73f98663745bb608b 393 SUPERFAMILY SSF46689 31 156 1.75E-10 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS01360 86483bf44bd2fff73f98663745bb608b 393 Pfam PF13565 Homeodomain-like domain 66 155 3.7E-11 T 26-04-2017 A4V04_RS01360 86483bf44bd2fff73f98663745bb608b 393 Gene3D G3DSA:3.30.420.10 251 376 5.9E-10 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS01360 86483bf44bd2fff73f98663745bb608b 393 SUPERFAMILY SSF53098 240 376 2.85E-10 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS01360 86483bf44bd2fff73f98663745bb608b 393 Gene3D G3DSA:1.10.10.10 34 77 2.3E-5 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01360 86483bf44bd2fff73f98663745bb608b 393 Pfam PF13358 DDE superfamily endonuclease 215 361 1.3E-24 T 26-04-2017 A4V04_RS08895 2127347871a4c97a5031428dcefbfb0f 401 Pfam PF12704 MacB-like periplasmic core domain 20 238 8.8E-43 T 26-04-2017 IPR025857 MacB-like periplasmic core domain A4V04_RS08895 2127347871a4c97a5031428dcefbfb0f 401 Pfam PF02687 FtsX-like permease family 282 394 3.4E-22 T 26-04-2017 IPR003838 ABC transporter permease protein domain GO:0016020 A4V04_RS03870 55e2d347356caddd87776a1614eff80d 534 Pfam PF00884 Sulfatase 215 500 4.6E-23 T 26-04-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 A4V04_RS03870 55e2d347356caddd87776a1614eff80d 534 Gene3D G3DSA:3.40.720.10 216 492 1.1E-8 T 26-04-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A4V04_RS03870 55e2d347356caddd87776a1614eff80d 534 SUPERFAMILY SSF53649 213 482 8.18E-13 T 26-04-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A4V04_RS09525 306736a6364a59bd817780e7bb91c6d4 222 SUPERFAMILY SSF51735 1 221 1.63E-35 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS09525 306736a6364a59bd817780e7bb91c6d4 222 Gene3D G3DSA:3.40.50.720 1 222 4.2E-36 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS09525 306736a6364a59bd817780e7bb91c6d4 222 Pfam PF13460 NAD(P)H-binding 8 211 9.1E-29 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS07165 5479eec3c71c42ad9e76361353815155 133 SUPERFAMILY SSF48695 33 125 3.12E-11 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS07165 5479eec3c71c42ad9e76361353815155 133 Pfam PF14537 Cytochrome c3 29 123 2.3E-13 T 26-04-2017 A4V04_RS07165 5479eec3c71c42ad9e76361353815155 133 Gene3D G3DSA:3.90.10.10 19 126 3.0E-11 T 26-04-2017 A4V04_RS13055 3e9650dc6b1e18a9297ba39f366a443b 591 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 130 584 3.4E-112 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS13055 3e9650dc6b1e18a9297ba39f366a443b 591 Pfam PF00890 FAD binding domain 130 573 1.4E-83 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS13055 3e9650dc6b1e18a9297ba39f366a443b 591 Gene3D G3DSA:3.90.700.10 376 523 5.3E-24 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS13055 3e9650dc6b1e18a9297ba39f366a443b 591 Pfam PF04205 FMN-binding domain 33 104 3.5E-8 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS13055 3e9650dc6b1e18a9297ba39f366a443b 591 SMART SM00900 33 106 5.2E-11 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS13055 3e9650dc6b1e18a9297ba39f366a443b 591 SUPERFAMILY SSF56425 376 533 2.44E-27 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS13055 3e9650dc6b1e18a9297ba39f366a443b 591 SUPERFAMILY SSF51905 532 589 1.09E-58 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS13055 3e9650dc6b1e18a9297ba39f366a443b 591 SUPERFAMILY SSF51905 120 387 1.09E-58 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS13055 3e9650dc6b1e18a9297ba39f366a443b 591 Gene3D G3DSA:3.50.50.60 115 370 1.2E-93 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS13055 3e9650dc6b1e18a9297ba39f366a443b 591 Gene3D G3DSA:3.50.50.60 529 589 1.2E-93 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS03570 6f56e81746e1f092c0cbd292509015f3 308 Gene3D G3DSA:3.40.800.20 3 307 7.1E-80 T 26-04-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4V04_RS03570 6f56e81746e1f092c0cbd292509015f3 308 Pfam PF00850 Histone deacetylase domain 22 305 7.2E-66 T 26-04-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4V04_RS03570 6f56e81746e1f092c0cbd292509015f3 308 SUPERFAMILY SSF52768 2 307 8.63E-85 T 26-04-2017 A4V04_RS03570 6f56e81746e1f092c0cbd292509015f3 308 PRINTS PR01270 Histone deacetylase superfamily signature 235 245 6.6E-17 T 26-04-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4V04_RS03570 6f56e81746e1f092c0cbd292509015f3 308 PRINTS PR01270 Histone deacetylase superfamily signature 157 172 6.6E-17 T 26-04-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4V04_RS03570 6f56e81746e1f092c0cbd292509015f3 308 PRINTS PR01270 Histone deacetylase superfamily signature 123 146 6.6E-17 T 26-04-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4V04_RS08690 885fbe49746dd306a7fe5595b26e6c2b 335 Pfam PF02562 PhoH-like protein 123 325 4.7E-94 T 26-04-2017 IPR003714 PhoH-like protein GO:0005524 A4V04_RS08690 885fbe49746dd306a7fe5595b26e6c2b 335 SMART SM00322 15 78 0.0034 T 26-04-2017 IPR004087 K Homology domain GO:0003676 A4V04_RS08690 885fbe49746dd306a7fe5595b26e6c2b 335 Gene3D G3DSA:3.40.50.300 121 324 5.6E-87 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08690 885fbe49746dd306a7fe5595b26e6c2b 335 SUPERFAMILY SSF52540 103 300 3.79E-41 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09340 d6997bc35d9af5d2b2edb02c0cb14997 312 Pfam PF03547 Membrane transport protein 10 153 7.2E-10 T 26-04-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A4V04_RS09340 d6997bc35d9af5d2b2edb02c0cb14997 312 Pfam PF03547 Membrane transport protein 162 304 1.3E-15 T 26-04-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A4V04_RS12905 a57212ee09d52743ac5d5401fff5655b 359 Pfam PF13609 Gram-negative porin 9 334 5.2E-39 T 26-04-2017 A4V04_RS12905 a57212ee09d52743ac5d5401fff5655b 359 PRINTS PR00184 Neisseria sp. porin signature 155 172 1.4E-8 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS12905 a57212ee09d52743ac5d5401fff5655b 359 PRINTS PR00184 Neisseria sp. porin signature 310 334 1.4E-8 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS12905 a57212ee09d52743ac5d5401fff5655b 359 PRINTS PR00184 Neisseria sp. porin signature 53 78 1.4E-8 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS12905 a57212ee09d52743ac5d5401fff5655b 359 Gene3D G3DSA:2.40.160.10 22 359 3.0E-66 T 26-04-2017 IPR023614 Porin domain A4V04_RS12905 a57212ee09d52743ac5d5401fff5655b 359 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 187 199 2.0E-6 T 26-04-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 A4V04_RS12905 a57212ee09d52743ac5d5401fff5655b 359 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 313 330 2.0E-6 T 26-04-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 A4V04_RS12905 a57212ee09d52743ac5d5401fff5655b 359 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 51 62 2.0E-6 T 26-04-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 A4V04_RS12905 a57212ee09d52743ac5d5401fff5655b 359 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 156 167 2.0E-6 T 26-04-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 A4V04_RS12905 a57212ee09d52743ac5d5401fff5655b 359 SUPERFAMILY SSF56935 21 359 5.19E-53 T 26-04-2017 A4V04_RS10815 e5da105fdae9515cd868512e92ebc8c5 204 SUPERFAMILY SSF46955 8 48 9.16E-6 T 26-04-2017 IPR009061 Putative DNA-binding domain A4V04_RS10815 e5da105fdae9515cd868512e92ebc8c5 204 SMART SM00857 63 195 4.7E-10 T 26-04-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4V04_RS10815 e5da105fdae9515cd868512e92ebc8c5 204 ProSitePatterns PS00397 Site-specific recombinases active site. 66 74 - T 26-04-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A4V04_RS10815 e5da105fdae9515cd868512e92ebc8c5 204 Gene3D G3DSA:1.10.1660.10 9 53 6.6E-5 T 26-04-2017 A4V04_RS10815 e5da105fdae9515cd868512e92ebc8c5 204 Pfam PF00376 MerR family regulatory protein 10 47 1.0E-6 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS10815 e5da105fdae9515cd868512e92ebc8c5 204 Gene3D G3DSA:3.40.50.1390 63 176 5.6E-16 T 26-04-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4V04_RS10815 e5da105fdae9515cd868512e92ebc8c5 204 Pfam PF00239 Resolvase, N terminal domain 64 184 2.4E-15 T 26-04-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4V04_RS10815 e5da105fdae9515cd868512e92ebc8c5 204 SUPERFAMILY SSF53041 62 191 2.62E-21 T 26-04-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4V04_RS02100 434d4dbe085161f53eb364883e7b17b7 341 Gene3D G3DSA:3.90.226.10 68 128 2.9E-4 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS02100 434d4dbe085161f53eb364883e7b17b7 341 Pfam PF01972 Serine dehydrogenase proteinase 83 279 5.5E-11 T 26-04-2017 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 A4V04_RS02100 434d4dbe085161f53eb364883e7b17b7 341 SUPERFAMILY SSF52096 70 159 1.66E-6 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS02350 3cfd4c47bd53bbb40afcaa73559dd880 489 Pfam PF00890 FAD binding domain 42 471 1.5E-76 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02350 3cfd4c47bd53bbb40afcaa73559dd880 489 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 42 483 7.9E-120 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS02350 3cfd4c47bd53bbb40afcaa73559dd880 489 SUPERFAMILY SSF51905 431 488 6.66E-61 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02350 3cfd4c47bd53bbb40afcaa73559dd880 489 SUPERFAMILY SSF51905 27 293 6.66E-61 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02350 3cfd4c47bd53bbb40afcaa73559dd880 489 SUPERFAMILY SSF56425 287 432 2.51E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02350 3cfd4c47bd53bbb40afcaa73559dd880 489 Gene3D G3DSA:3.90.700.10 293 418 1.1E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02350 3cfd4c47bd53bbb40afcaa73559dd880 489 Gene3D G3DSA:3.50.50.60 428 486 1.5E-99 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02350 3cfd4c47bd53bbb40afcaa73559dd880 489 Gene3D G3DSA:3.50.50.60 29 276 1.5E-99 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02350 3cfd4c47bd53bbb40afcaa73559dd880 489 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 43 62 6.9E-5 T 26-04-2017 A4V04_RS02350 3cfd4c47bd53bbb40afcaa73559dd880 489 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 436 458 6.9E-5 T 26-04-2017 A4V04_RS00040 21d697dabca49023e9fdebe68a0b0709 507 SUPERFAMILY SSF55681 164 504 8.0E-116 T 26-04-2017 A4V04_RS00040 21d697dabca49023e9fdebe68a0b0709 507 Gene3D G3DSA:2.40.50.140 18 156 7.1E-47 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS00040 21d697dabca49023e9fdebe68a0b0709 507 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 18 506 2.3E-200 T 26-04-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4V04_RS00040 21d697dabca49023e9fdebe68a0b0709 507 Gene3D G3DSA:3.30.930.10 159 502 1.8E-115 T 26-04-2017 A4V04_RS00040 21d697dabca49023e9fdebe68a0b0709 507 Pfam PF00152 tRNA synthetases class II (D, K and N) 164 503 2.4E-80 T 26-04-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4V04_RS00040 21d697dabca49023e9fdebe68a0b0709 507 SUPERFAMILY SSF50249 16 157 1.29E-39 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS00040 21d697dabca49023e9fdebe68a0b0709 507 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 23 506 43.664 T 26-04-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4V04_RS00040 21d697dabca49023e9fdebe68a0b0709 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 246 259 8.5E-39 T 26-04-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4V04_RS00040 21d697dabca49023e9fdebe68a0b0709 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 264 281 8.5E-39 T 26-04-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4V04_RS00040 21d697dabca49023e9fdebe68a0b0709 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 201 211 8.5E-39 T 26-04-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4V04_RS00040 21d697dabca49023e9fdebe68a0b0709 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 217 233 8.5E-39 T 26-04-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4V04_RS00040 21d697dabca49023e9fdebe68a0b0709 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 388 404 8.5E-39 T 26-04-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4V04_RS00040 21d697dabca49023e9fdebe68a0b0709 507 Pfam PF01336 OB-fold nucleic acid binding domain 70 148 2.0E-13 T 26-04-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A4V04_RS10685 a89edcdd4cb3cd7d89b72e43fe8d00a8 138 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 85 1.8E-28 T 26-04-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4V04_RS10685 a89edcdd4cb3cd7d89b72e43fe8d00a8 138 SUPERFAMILY SSF51344 5 87 1.57E-23 T 26-04-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4V04_RS10685 a89edcdd4cb3cd7d89b72e43fe8d00a8 138 Gene3D G3DSA:2.60.15.10 1 90 2.6E-30 T 26-04-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4V04_RS10685 a89edcdd4cb3cd7d89b72e43fe8d00a8 138 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 132 21.362 T 26-04-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4V04_RS10685 a89edcdd4cb3cd7d89b72e43fe8d00a8 138 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 133 2.5E-38 T 26-04-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4V04_RS10685 a89edcdd4cb3cd7d89b72e43fe8d00a8 138 SUPERFAMILY SSF46604 89 137 1.02E-6 T 26-04-2017 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210 A4V04_RS10685 a89edcdd4cb3cd7d89b72e43fe8d00a8 138 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 91 2.0E-26 T 26-04-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4V04_RS12590 41c99ab4e3e209adf637df34b5a7087c 253 Pfam PF00977 Histidine biosynthesis protein 5 235 2.1E-88 T 26-04-2017 IPR006062 Histidine biosynthesis GO:0000105 A4V04_RS12590 41c99ab4e3e209adf637df34b5a7087c 253 SUPERFAMILY SSF51366 1 251 1.18E-84 T 26-04-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A4V04_RS12590 41c99ab4e3e209adf637df34b5a7087c 253 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 251 3.6E-113 T 26-04-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A4V04_RS12590 41c99ab4e3e209adf637df34b5a7087c 253 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 251 48.794 T 26-04-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A4V04_RS12590 41c99ab4e3e209adf637df34b5a7087c 253 Gene3D G3DSA:3.20.20.70 4 252 3.5E-106 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS03400 4d6b3448a81b13b53ded4c77311ab227 246 SUPERFAMILY SSF52540 4 233 6.14E-58 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03400 4d6b3448a81b13b53ded4c77311ab227 246 SMART SM00382 28 218 1.1E-11 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS03400 4d6b3448a81b13b53ded4c77311ab227 246 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS03400 4d6b3448a81b13b53ded4c77311ab227 246 Gene3D G3DSA:3.40.50.300 3 243 3.8E-66 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03400 4d6b3448a81b13b53ded4c77311ab227 246 Pfam PF00005 ABC transporter 19 166 1.2E-31 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS09190 9b1d4368e8a9600fb64607cf6a530b79 276 Pfam PF13247 4Fe-4S dicluster domain 141 236 7.1E-21 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS09190 9b1d4368e8a9600fb64607cf6a530b79 276 SUPERFAMILY SSF54862 80 270 6.17E-54 T 26-04-2017 A4V04_RS09190 9b1d4368e8a9600fb64607cf6a530b79 276 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 180 191 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS09190 9b1d4368e8a9600fb64607cf6a530b79 276 Gene3D G3DSA:3.30.70.20 140 274 8.3E-39 T 26-04-2017 A4V04_RS09190 9b1d4368e8a9600fb64607cf6a530b79 276 Pfam PF12837 4Fe-4S binding domain 83 102 2.2E-6 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS09190 9b1d4368e8a9600fb64607cf6a530b79 276 Gene3D G3DSA:3.30.70.20 73 132 7.6E-6 T 26-04-2017 A4V04_RS05690 40506a545a748532a4cefe226ae8c05a 572 Pfam PF01609 Transposase DDE domain 247 516 3.1E-12 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS05690 40506a545a748532a4cefe226ae8c05a 572 SUPERFAMILY SSF53098 210 524 4.78E-7 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS08725 b3bb4a8b6d40c5457e7a3381438771bf 273 Pfam PF08543 Phosphomethylpyrimidine kinase 15 265 1.9E-91 T 26-04-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 A4V04_RS08725 b3bb4a8b6d40c5457e7a3381438771bf 273 Gene3D G3DSA:3.40.1190.20 5 268 1.0E-96 T 26-04-2017 IPR029056 Ribokinase-like A4V04_RS08725 b3bb4a8b6d40c5457e7a3381438771bf 273 SUPERFAMILY SSF53613 5 272 2.65E-73 T 26-04-2017 IPR029056 Ribokinase-like A4V04_RS08725 b3bb4a8b6d40c5457e7a3381438771bf 273 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 8 268 6.0E-95 T 26-04-2017 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4V04_RS11575 62f134b6ad99e9b79e981d7fc5073f3a 184 Gene3D G3DSA:1.10.260.40 8 72 4.8E-23 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS11575 62f134b6ad99e9b79e981d7fc5073f3a 184 Pfam PF07883 Cupin domain 115 179 1.4E-9 T 26-04-2017 IPR013096 Cupin 2, conserved barrel A4V04_RS11575 62f134b6ad99e9b79e981d7fc5073f3a 184 Gene3D G3DSA:2.60.120.10 93 182 6.0E-25 T 26-04-2017 IPR014710 RmlC-like jelly roll fold A4V04_RS11575 62f134b6ad99e9b79e981d7fc5073f3a 184 SUPERFAMILY SSF51182 51 183 1.53E-18 T 26-04-2017 IPR011051 RmlC-like cupin domain A4V04_RS11575 62f134b6ad99e9b79e981d7fc5073f3a 184 SUPERFAMILY SSF47413 4 69 7.24E-19 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS11575 62f134b6ad99e9b79e981d7fc5073f3a 184 SMART SM00530 11 66 1.4E-16 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS11575 62f134b6ad99e9b79e981d7fc5073f3a 184 Pfam PF01381 Helix-turn-helix 12 65 2.3E-17 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS07665 2636b30053ed9521b6ce786b024635a7 496 Gene3D G3DSA:3.90.700.10 277 419 1.3E-23 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS07665 2636b30053ed9521b6ce786b024635a7 496 Gene3D G3DSA:3.50.50.60 21 253 2.9E-72 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07665 2636b30053ed9521b6ce786b024635a7 496 Gene3D G3DSA:3.50.50.60 426 489 2.9E-72 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07665 2636b30053ed9521b6ce786b024635a7 496 SUPERFAMILY SSF51905 429 489 1.2E-48 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07665 2636b30053ed9521b6ce786b024635a7 496 SUPERFAMILY SSF51905 17 270 1.2E-48 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07665 2636b30053ed9521b6ce786b024635a7 496 SUPERFAMILY SSF56425 275 430 4.71E-23 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS07665 2636b30053ed9521b6ce786b024635a7 496 Pfam PF00890 FAD binding domain 27 461 1.4E-51 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS06820 411c520b0fa8b954ec004cda2f24dfa6 305 ProDom PD005668 HYDROGENASE HUPH HYDROGENASE-1 EXPRESSION/FORMATION OPERON PROTEIN C-TERMINAL EXPRESSION HYAF HOXQ 82 157 9.0E-7 T 26-04-2017 IPR006894 HupH hydrogenase expression protein, C-terminal A4V04_RS06820 411c520b0fa8b954ec004cda2f24dfa6 305 ProDom PD005668 HYDROGENASE HUPH HYDROGENASE-1 EXPRESSION/FORMATION OPERON PROTEIN C-TERMINAL EXPRESSION HYAF HOXQ 174 288 7.0E-25 T 26-04-2017 IPR006894 HupH hydrogenase expression protein, C-terminal A4V04_RS06820 411c520b0fa8b954ec004cda2f24dfa6 305 Pfam PF04809 HupH hydrogenase expression protein, C-terminal conserved region 59 156 3.9E-10 T 26-04-2017 IPR006894 HupH hydrogenase expression protein, C-terminal A4V04_RS06820 411c520b0fa8b954ec004cda2f24dfa6 305 Pfam PF04809 HupH hydrogenase expression protein, C-terminal conserved region 175 293 6.3E-39 T 26-04-2017 IPR006894 HupH hydrogenase expression protein, C-terminal A4V04_RS01170 56fa60b1ffa7c56eadd73a35ec123087 599 Pfam PF03577 Peptidase family C69 24 374 4.9E-46 T 26-04-2017 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 A4V04_RS13025 fffc566d61e6d23d4002bc8dd88ec550 403 SUPERFAMILY SSF116734 204 402 1.06E-28 T 26-04-2017 A4V04_RS13025 fffc566d61e6d23d4002bc8dd88ec550 403 Pfam PF01420 Type I restriction modification DNA specificity domain 217 389 2.3E-4 T 26-04-2017 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A4V04_RS13025 fffc566d61e6d23d4002bc8dd88ec550 403 SUPERFAMILY SSF116734 22 201 6.87E-27 T 26-04-2017 A4V04_RS08510 0a19fed9d35267dd3d1188409d307d05 250 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 249 3.1E-56 T 26-04-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A4V04_RS08510 0a19fed9d35267dd3d1188409d307d05 250 SUPERFAMILY SSF102705 1 249 3.66E-73 T 26-04-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A4V04_RS08510 0a19fed9d35267dd3d1188409d307d05 250 Gene3D G3DSA:3.40.1390.30 1 108 1.9E-30 T 26-04-2017 A4V04_RS08510 0a19fed9d35267dd3d1188409d307d05 250 Gene3D G3DSA:3.40.1390.30 109 214 1.8E-24 T 26-04-2017 A4V04_RS08510 0a19fed9d35267dd3d1188409d307d05 250 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 238 1.5E-54 T 26-04-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A4V04_RS06065 cd4fc2ae728ec1a255ccc0bfaf2afc5c 553 Pfam PF02554 Carbon starvation protein CstA 1 344 2.9E-127 T 26-04-2017 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A4V04_RS06065 cd4fc2ae728ec1a255ccc0bfaf2afc5c 553 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 375 496 1.4E-37 T 26-04-2017 IPR025299 CstA, C-terminal domain A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 Gene3D G3DSA:2.40.10.10 179 287 8.4E-45 T 26-04-2017 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 SUPERFAMILY SSF50156 402 482 2.23E-13 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 Pfam PF13365 Trypsin-like peptidase domain 114 247 1.1E-35 T 26-04-2017 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 Pfam PF13180 PDZ domain 401 481 3.6E-9 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 Pfam PF13180 PDZ domain 287 377 1.1E-18 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 SUPERFAMILY SSF50156 244 369 2.23E-24 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 PRINTS PR00834 HtrA/DegQ protease family signature 184 208 2.4E-52 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 PRINTS PR00834 HtrA/DegQ protease family signature 240 257 2.4E-52 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 PRINTS PR00834 HtrA/DegQ protease family signature 123 135 2.4E-52 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 PRINTS PR00834 HtrA/DegQ protease family signature 218 235 2.4E-52 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 PRINTS PR00834 HtrA/DegQ protease family signature 144 164 2.4E-52 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 PRINTS PR00834 HtrA/DegQ protease family signature 326 338 2.4E-52 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 SUPERFAMILY SSF50494 48 279 1.23E-66 T 26-04-2017 IPR009003 Peptidase S1, PA clan A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 Gene3D G3DSA:2.30.42.10 400 485 8.1E-17 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 Gene3D G3DSA:2.30.42.10 288 384 3.9E-31 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 SMART SM00228 286 368 7.8E-15 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 SMART SM00228 399 473 2.1E-7 T 26-04-2017 IPR001478 PDZ domain GO:0005515 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 Gene3D G3DSA:2.40.10.10 101 178 1.5E-36 T 26-04-2017 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 Gene3D G3DSA:2.40.10.10 42 69 1.5E-36 T 26-04-2017 A4V04_RS10840 50bc532ffff7e8095fd5cefbf7be2cd0 487 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 49 478 2.0E-150 T 26-04-2017 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 A4V04_RS03845 a073a30298701ad184926e0ce519ca5a 299 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 87 109 - T 26-04-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4V04_RS03845 a073a30298701ad184926e0ce519ca5a 299 Pfam PF01066 CDP-alcohol phosphatidyltransferase 46 109 3.3E-14 T 26-04-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4V04_RS03845 a073a30298701ad184926e0ce519ca5a 299 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 51 215 3.8E-34 T 26-04-2017 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 A4V04_RS01835 c1b37b4e19d9be28ea5ed040c8ca1f76 97 TIGRFAM TIGR02762 TraL_TIGR: type IV conjugative transfer system protein TraL 11 95 7.4E-20 T 26-04-2017 IPR009838 Type IV conjugative transfer system, protein TraL GO:0000746|GO:0019867 A4V04_RS01835 c1b37b4e19d9be28ea5ed040c8ca1f76 97 Pfam PF07178 TraL protein 11 96 4.6E-25 T 26-04-2017 IPR009838 Type IV conjugative transfer system, protein TraL GO:0000746|GO:0019867 A4V04_RS01030 10d4d5a9d15c35c8116e086160c47215 272 SUPERFAMILY SSF53681 117 267 7.85E-33 T 26-04-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS01030 10d4d5a9d15c35c8116e086160c47215 272 SUPERFAMILY SSF53681 14 114 1.05E-33 T 26-04-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS01030 10d4d5a9d15c35c8116e086160c47215 272 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 78 86 - T 26-04-2017 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS01030 10d4d5a9d15c35c8116e086160c47215 272 Hamap MF_00258 Glutamate racemase [murI]. 12 264 34.077 T 26-04-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS01030 10d4d5a9d15c35c8116e086160c47215 272 Pfam PF01177 Asp/Glu/Hydantoin racemase 14 224 3.8E-31 T 26-04-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS01030 10d4d5a9d15c35c8116e086160c47215 272 TIGRFAM TIGR00067 glut_race: glutamate racemase 14 258 2.0E-65 T 26-04-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS01030 10d4d5a9d15c35c8116e086160c47215 272 Gene3D G3DSA:3.40.50.1860 12 182 2.6E-51 T 26-04-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4V04_RS05230 5252ca01fd5dc0c8a68a255c48f0da23 923 Gene3D G3DSA:3.30.830.10 53 271 1.0E-54 T 26-04-2017 IPR011237 Peptidase M16 domain GO:0046872 A4V04_RS05230 5252ca01fd5dc0c8a68a255c48f0da23 923 Pfam PF00675 Insulinase (Peptidase family M16) 64 210 1.9E-21 T 26-04-2017 IPR011765 Peptidase M16, N-terminal A4V04_RS05230 5252ca01fd5dc0c8a68a255c48f0da23 923 Pfam PF05193 Peptidase M16 inactive domain 669 845 9.5E-24 T 26-04-2017 IPR007863 Peptidase M16, C-terminal A4V04_RS05230 5252ca01fd5dc0c8a68a255c48f0da23 923 Pfam PF05193 Peptidase M16 inactive domain 220 393 1.8E-24 T 26-04-2017 IPR007863 Peptidase M16, C-terminal A4V04_RS05230 5252ca01fd5dc0c8a68a255c48f0da23 923 SUPERFAMILY SSF63411 728 918 9.09E-30 T 26-04-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4V04_RS05230 5252ca01fd5dc0c8a68a255c48f0da23 923 SUPERFAMILY SSF63411 513 711 9.67E-22 T 26-04-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4V04_RS05230 5252ca01fd5dc0c8a68a255c48f0da23 923 SUPERFAMILY SSF63411 278 464 6.54E-23 T 26-04-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4V04_RS05230 5252ca01fd5dc0c8a68a255c48f0da23 923 Gene3D G3DSA:3.30.830.10 306 457 8.9E-8 T 26-04-2017 IPR011237 Peptidase M16 domain GO:0046872 A4V04_RS05230 5252ca01fd5dc0c8a68a255c48f0da23 923 Gene3D G3DSA:3.30.830.10 514 693 2.5E-21 T 26-04-2017 IPR011237 Peptidase M16 domain GO:0046872 A4V04_RS05230 5252ca01fd5dc0c8a68a255c48f0da23 923 Gene3D G3DSA:3.30.830.10 727 914 9.4E-26 T 26-04-2017 IPR011237 Peptidase M16 domain GO:0046872 A4V04_RS05230 5252ca01fd5dc0c8a68a255c48f0da23 923 SUPERFAMILY SSF63411 53 269 2.02E-53 T 26-04-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4V04_RS05230 5252ca01fd5dc0c8a68a255c48f0da23 923 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 85 108 - T 26-04-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 A4V04_RS03440 2845f16e3b315b6106dc07365d7ab562 347 Gene3D G3DSA:3.40.50.1170 22 230 1.5E-72 T 26-04-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A4V04_RS03440 2845f16e3b315b6106dc07365d7ab562 347 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 103 113 - T 26-04-2017 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A4V04_RS03440 2845f16e3b315b6106dc07365d7ab562 347 SMART SM00870 24 341 8.4E-143 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS03440 2845f16e3b315b6106dc07365d7ab562 347 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 27 35 - T 26-04-2017 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A4V04_RS03440 2845f16e3b315b6106dc07365d7ab562 347 PRINTS PR00139 Asparaginase/glutaminase family signature 25 36 1.1E-22 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS03440 2845f16e3b315b6106dc07365d7ab562 347 PRINTS PR00139 Asparaginase/glutaminase family signature 102 120 1.1E-22 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS03440 2845f16e3b315b6106dc07365d7ab562 347 PRINTS PR00139 Asparaginase/glutaminase family signature 281 299 1.1E-22 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS03440 2845f16e3b315b6106dc07365d7ab562 347 PIRSF PIRSF500176 21 347 3.1E-84 T 26-04-2017 A4V04_RS03440 2845f16e3b315b6106dc07365d7ab562 347 Pfam PF00710 Asparaginase, N-terminal 24 214 2.9E-61 T 26-04-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A4V04_RS03440 2845f16e3b315b6106dc07365d7ab562 347 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 4 347 9.5E-142 T 26-04-2017 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 A4V04_RS03440 2845f16e3b315b6106dc07365d7ab562 347 Gene3D G3DSA:3.40.50.40 234 345 8.1E-40 T 26-04-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 A4V04_RS03440 2845f16e3b315b6106dc07365d7ab562 347 PIRSF PIRSF001220 20 347 6.4E-93 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS03440 2845f16e3b315b6106dc07365d7ab562 347 SUPERFAMILY SSF53774 23 346 9.68E-106 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS13220 7dfd26ade177d7be9ab32d946c47a357 406 PIRSF PIRSF005572 6 386 9.5E-134 T 26-04-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A4V04_RS13220 7dfd26ade177d7be9ab32d946c47a357 406 Gene3D G3DSA:3.40.640.10 21 255 6.6E-98 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS13220 7dfd26ade177d7be9ab32d946c47a357 406 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 5 397 53.555 T 26-04-2017 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 A4V04_RS13220 7dfd26ade177d7be9ab32d946c47a357 406 SUPERFAMILY SSF53383 8 392 3.03E-111 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS13220 7dfd26ade177d7be9ab32d946c47a357 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 199 218 - T 26-04-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A4V04_RS13220 7dfd26ade177d7be9ab32d946c47a357 406 Gene3D G3DSA:3.90.1150.10 256 377 5.0E-49 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS13220 7dfd26ade177d7be9ab32d946c47a357 406 Pfam PF00266 Aminotransferase class-V 9 370 2.9E-89 T 26-04-2017 IPR000192 Aminotransferase class V domain A4V04_RS13220 7dfd26ade177d7be9ab32d946c47a357 406 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 5 406 2.0E-214 T 26-04-2017 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 A4V04_RS05045 96c1ef3e8c1de826a648db4b2bda19b2 90 SMART SM00411 1 90 4.0E-39 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS05045 96c1ef3e8c1de826a648db4b2bda19b2 90 Gene3D G3DSA:4.10.520.10 1 90 3.9E-34 T 26-04-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4V04_RS05045 96c1ef3e8c1de826a648db4b2bda19b2 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 5.7E-15 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS05045 96c1ef3e8c1de826a648db4b2bda19b2 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 5.7E-15 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS05045 96c1ef3e8c1de826a648db4b2bda19b2 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 5.7E-15 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS05045 96c1ef3e8c1de826a648db4b2bda19b2 90 Pfam PF00216 Bacterial DNA-binding protein 1 89 2.7E-32 T 26-04-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 A4V04_RS05045 96c1ef3e8c1de826a648db4b2bda19b2 90 SUPERFAMILY SSF47729 1 90 6.33E-31 T 26-04-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4V04_RS11930 31e8141e5ec69aa7489ed416095abdad 250 SUPERFAMILY SSF52218 5 142 3.28E-13 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS11930 31e8141e5ec69aa7489ed416095abdad 250 Pfam PF13187 4Fe-4S dicluster domain 179 220 1.3E-7 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS11930 31e8141e5ec69aa7489ed416095abdad 250 Gene3D G3DSA:3.40.50.360 5 141 1.5E-11 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS11930 31e8141e5ec69aa7489ed416095abdad 250 Gene3D G3DSA:3.30.70.20 170 220 1.7E-14 T 26-04-2017 A4V04_RS11930 31e8141e5ec69aa7489ed416095abdad 250 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 207 218 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS11930 31e8141e5ec69aa7489ed416095abdad 250 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 179 190 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS11930 31e8141e5ec69aa7489ed416095abdad 250 SUPERFAMILY SSF54862 171 222 3.59E-14 T 26-04-2017 A4V04_RS06570 69ce8e193b696d4d741dcac7b789679d 298 Pfam PF01385 Probable transposase 51 149 7.8E-12 T 26-04-2017 IPR001959 Probable transposase, IS891/IS1136/IS1341 A4V04_RS06570 69ce8e193b696d4d741dcac7b789679d 298 Pfam PF07282 Putative transposase DNA-binding domain 168 247 3.0E-9 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS06570 69ce8e193b696d4d741dcac7b789679d 298 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 117 195 9.2E-19 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS09085 dec8544f6326dbbe2b45c1df18ebbef1 450 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 106 428 7.0E-62 T 26-04-2017 IPR004108 Iron hydrogenase, large subunit, C-terminal A4V04_RS09085 dec8544f6326dbbe2b45c1df18ebbef1 450 Gene3D G3DSA:3.30.70.20 32 78 8.3E-15 T 26-04-2017 A4V04_RS09085 dec8544f6326dbbe2b45c1df18ebbef1 450 Gene3D G3DSA:3.40.50.1780 196 342 9.7E-61 T 26-04-2017 A4V04_RS09085 dec8544f6326dbbe2b45c1df18ebbef1 450 Gene3D G3DSA:3.40.50.1780 79 131 9.7E-61 T 26-04-2017 A4V04_RS09085 dec8544f6326dbbe2b45c1df18ebbef1 450 Pfam PF13187 4Fe-4S dicluster domain 43 88 7.1E-7 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS09085 dec8544f6326dbbe2b45c1df18ebbef1 450 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS09085 dec8544f6326dbbe2b45c1df18ebbef1 450 SUPERFAMILY SSF53920 73 435 2.62E-80 T 26-04-2017 IPR009016 Iron hydrogenase A4V04_RS09085 dec8544f6326dbbe2b45c1df18ebbef1 450 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 73 84 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS09085 dec8544f6326dbbe2b45c1df18ebbef1 450 SUPERFAMILY SSF54862 28 124 1.42E-20 T 26-04-2017 A4V04_RS01545 9d278b2ca7a825bf39a445fa0892103f 1360 Pfam PF00176 SNF2 family N-terminal domain 926 1184 6.2E-62 T 26-04-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 A4V04_RS01545 9d278b2ca7a825bf39a445fa0892103f 1360 Gene3D G3DSA:3.40.50.300 1192 1336 1.7E-21 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01545 9d278b2ca7a825bf39a445fa0892103f 1360 SMART SM00490 1223 1305 7.9E-23 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS01545 9d278b2ca7a825bf39a445fa0892103f 1360 Pfam PF00271 Helicase conserved C-terminal domain 1196 1305 7.8E-19 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS01545 9d278b2ca7a825bf39a445fa0892103f 1360 Gene3D G3DSA:3.40.50.300 900 1074 4.9E-29 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01545 9d278b2ca7a825bf39a445fa0892103f 1360 SUPERFAMILY SSF52540 1118 1358 6.26E-63 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01545 9d278b2ca7a825bf39a445fa0892103f 1360 SUPERFAMILY SSF52540 896 1117 1.68E-57 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01545 9d278b2ca7a825bf39a445fa0892103f 1360 SMART SM00487 906 1089 1.2E-33 T 26-04-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4V04_RS01545 9d278b2ca7a825bf39a445fa0892103f 1360 Pfam PF08455 Bacterial SNF2 helicase associated 549 903 2.9E-9 T 26-04-2017 IPR013663 Helicase, SWF/SNF/SWI type, bacterial A4V04_RS10145 329646cb387bbab022f215eb0cf7b95e 486 SUPERFAMILY SSF56425 298 427 6.28E-21 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10145 329646cb387bbab022f215eb0cf7b95e 486 SUPERFAMILY SSF51905 427 484 1.46E-49 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10145 329646cb387bbab022f215eb0cf7b95e 486 SUPERFAMILY SSF51905 25 281 1.46E-49 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10145 329646cb387bbab022f215eb0cf7b95e 486 Gene3D G3DSA:3.90.700.10 298 417 2.1E-19 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10145 329646cb387bbab022f215eb0cf7b95e 486 Gene3D G3DSA:3.50.50.60 424 484 9.6E-80 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10145 329646cb387bbab022f215eb0cf7b95e 486 Gene3D G3DSA:3.50.50.60 23 273 9.6E-80 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10145 329646cb387bbab022f215eb0cf7b95e 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 61 5.2E-9 T 26-04-2017 A4V04_RS10145 329646cb387bbab022f215eb0cf7b95e 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 444 459 5.2E-9 T 26-04-2017 A4V04_RS10145 329646cb387bbab022f215eb0cf7b95e 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 246 271 5.2E-9 T 26-04-2017 A4V04_RS10145 329646cb387bbab022f215eb0cf7b95e 486 Pfam PF00890 FAD binding domain 39 464 7.4E-54 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS05740 1008db8b2291244570c910106e8c71b2 338 Gene3D G3DSA:3.50.50.60 3 41 8.2E-6 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS05740 1008db8b2291244570c910106e8c71b2 338 SUPERFAMILY SSF51735 1 182 4.12E-76 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS05740 1008db8b2291244570c910106e8c71b2 338 Gene3D G3DSA:1.10.1040.10 42 325 4.1E-112 T 26-04-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4V04_RS05740 1008db8b2291244570c910106e8c71b2 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 7.9E-63 T 26-04-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4V04_RS05740 1008db8b2291244570c910106e8c71b2 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 5.8E-76 T 26-04-2017 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4V04_RS05740 1008db8b2291244570c910106e8c71b2 338 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 1 328 45.132 T 26-04-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4V04_RS05740 1008db8b2291244570c910106e8c71b2 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 326 1.6E-136 T 26-04-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4V04_RS05740 1008db8b2291244570c910106e8c71b2 338 SUPERFAMILY SSF48179 183 332 1.28E-67 T 26-04-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4V04_RS05350 52ae3032d2e53f108f2ef2fd44afbc54 84 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 13 73 14.406 T 26-04-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4V04_RS05350 52ae3032d2e53f108f2ef2fd44afbc54 84 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 13 68 1.6E-20 T 26-04-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4V04_RS05350 52ae3032d2e53f108f2ef2fd44afbc54 84 Pfam PF02609 Exonuclease VII small subunit 14 65 6.9E-19 T 26-04-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4V04_RS05350 52ae3032d2e53f108f2ef2fd44afbc54 84 SUPERFAMILY SSF116842 7 70 3.53E-19 T 26-04-2017 A4V04_RS05350 52ae3032d2e53f108f2ef2fd44afbc54 84 Gene3D G3DSA:1.10.287.1040 8 72 7.7E-23 T 26-04-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4V04_RS05350 52ae3032d2e53f108f2ef2fd44afbc54 84 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 13 54 6.0E-4 T 26-04-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4V04_RS08285 a206f65eaf6d99c2f299d79939c7fc42 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 31.13 T 26-04-2017 IPR023035 Ribosomal protein S9, bacterial/plastid A4V04_RS08285 a206f65eaf6d99c2f299d79939c7fc42 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 26-04-2017 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 A4V04_RS08285 a206f65eaf6d99c2f299d79939c7fc42 130 SUPERFAMILY SSF54211 6 130 1.29E-46 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS08285 a206f65eaf6d99c2f299d79939c7fc42 130 Gene3D G3DSA:3.30.230.10 6 130 2.5E-50 T 26-04-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4V04_RS08285 a206f65eaf6d99c2f299d79939c7fc42 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 5.7E-46 T 26-04-2017 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 A4V04_RS02310 ca90cbd9c631ca66ab7a14a6aa3539a2 342 Gene3D G3DSA:3.40.220.10 2 131 1.3E-9 T 26-04-2017 A4V04_RS02310 ca90cbd9c631ca66ab7a14a6aa3539a2 342 Pfam PF01661 Macro domain 18 131 6.5E-19 T 26-04-2017 IPR002589 Macro domain A4V04_RS02310 ca90cbd9c631ca66ab7a14a6aa3539a2 342 SUPERFAMILY SSF52949 1 148 9.25E-44 T 26-04-2017 A4V04_RS02310 ca90cbd9c631ca66ab7a14a6aa3539a2 342 SMART SM00506 1 133 9.0E-19 T 26-04-2017 IPR002589 Macro domain A4V04_RS09700 0b264b8a052665946b73396e65f5a8f5 326 Gene3D G3DSA:3.40.190.10 125 221 9.3E-7 T 26-04-2017 A4V04_RS09700 0b264b8a052665946b73396e65f5a8f5 326 SUPERFAMILY SSF53850 99 288 2.53E-11 T 26-04-2017 A4V04_RS09700 0b264b8a052665946b73396e65f5a8f5 326 Pfam PF03466 LysR substrate binding domain 99 282 1.2E-11 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS09700 0b264b8a052665946b73396e65f5a8f5 326 SUPERFAMILY SSF46785 8 86 1.87E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09700 0b264b8a052665946b73396e65f5a8f5 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 7.6E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09700 0b264b8a052665946b73396e65f5a8f5 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 7.6E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09700 0b264b8a052665946b73396e65f5a8f5 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 7.6E-8 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09700 0b264b8a052665946b73396e65f5a8f5 326 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 68 2.4E-17 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09700 0b264b8a052665946b73396e65f5a8f5 326 Gene3D G3DSA:1.10.10.10 8 83 1.2E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09245 489916a1e1f6b75706bee79360dd6448 151 SUPERFAMILY SSF54631 5 128 2.53E-32 T 26-04-2017 A4V04_RS09245 489916a1e1f6b75706bee79360dd6448 151 SMART SM00116 81 129 1.1E-8 T 26-04-2017 IPR000644 CBS domain A4V04_RS09245 489916a1e1f6b75706bee79360dd6448 151 SMART SM00116 15 63 4.1E-6 T 26-04-2017 IPR000644 CBS domain A4V04_RS09245 489916a1e1f6b75706bee79360dd6448 151 Gene3D G3DSA:3.10.580.10 5 125 2.3E-31 T 26-04-2017 A4V04_RS09245 489916a1e1f6b75706bee79360dd6448 151 Pfam PF00571 CBS domain 74 128 7.8E-13 T 26-04-2017 IPR000644 CBS domain A4V04_RS09245 489916a1e1f6b75706bee79360dd6448 151 Pfam PF00571 CBS domain 9 59 6.5E-10 T 26-04-2017 IPR000644 CBS domain A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Pfam PF04560 RNA polymerase Rpb2, domain 7 1294 1368 3.3E-26 T 26-04-2017 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Gene3D G3DSA:3.90.1100.10 20 156 2.9E-146 T 26-04-2017 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Gene3D G3DSA:3.90.1100.10 451 597 2.9E-146 T 26-04-2017 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Gene3D G3DSA:3.90.1100.10 665 719 2.9E-146 T 26-04-2017 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Gene3D G3DSA:2.40.50.100 721 798 1.7E-28 T 26-04-2017 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1082 1094 - T 26-04-2017 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Pfam PF10385 RNA polymerase beta subunit external 1 domain 597 662 3.6E-25 T 26-04-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Gene3D G3DSA:2.40.50.150 1064 1078 3.2E-55 T 26-04-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Gene3D G3DSA:2.40.50.150 834 943 3.2E-55 T 26-04-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Gene3D G3DSA:2.40.270.10 1079 1270 1.8E-84 T 26-04-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Gene3D G3DSA:2.40.270.10 799 826 1.8E-84 T 26-04-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Pfam PF04565 RNA polymerase Rpb2, domain 3 519 586 1.4E-31 T 26-04-2017 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Gene3D G3DSA:2.30.150.10 598 662 1.5E-28 T 26-04-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 SUPERFAMILY SSF64484 349 945 0.0 T 26-04-2017 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 SUPERFAMILY SSF64484 1058 1371 0.0 T 26-04-2017 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 SUPERFAMILY SSF64484 12 231 0.0 T 26-04-2017 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Pfam PF00562 RNA polymerase Rpb2, domain 6 724 1292 7.7E-159 T 26-04-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1366 0.0 T 26-04-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1370 12.193 T 26-04-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Pfam PF04563 RNA polymerase beta subunit 27 506 2.6E-35 T 26-04-2017 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Pfam PF04561 RNA polymerase Rpb2, domain 2 362 460 1.5E-10 T 26-04-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Pfam PF04561 RNA polymerase Rpb2, domain 2 156 237 8.2E-6 T 26-04-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Gene3D G3DSA:3.90.1110.10 352 450 5.1E-64 T 26-04-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11150 6c8f6f813eef7e7fc997858ad2543e97 1374 Gene3D G3DSA:3.90.1110.10 158 235 5.1E-64 T 26-04-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS06610 0da00a0a791f4340b1a58f71d7195e12 192 Gene3D G3DSA:1.10.10.60 145 181 2.1E-8 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS06610 0da00a0a791f4340b1a58f71d7195e12 192 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 26-04-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A4V04_RS06610 0da00a0a791f4340b1a58f71d7195e12 192 SUPERFAMILY SSF46689 142 183 5.12E-6 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS06610 0da00a0a791f4340b1a58f71d7195e12 192 Pfam PF00239 Resolvase, N terminal domain 4 138 1.2E-35 T 26-04-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4V04_RS06610 0da00a0a791f4340b1a58f71d7195e12 192 Gene3D G3DSA:3.40.50.1390 4 122 1.3E-32 T 26-04-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4V04_RS06610 0da00a0a791f4340b1a58f71d7195e12 192 SMART SM00857 3 139 2.9E-39 T 26-04-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4V04_RS06610 0da00a0a791f4340b1a58f71d7195e12 192 Pfam PF02796 Helix-turn-helix domain of resolvase 141 183 2.2E-6 T 26-04-2017 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 A4V04_RS06610 0da00a0a791f4340b1a58f71d7195e12 192 SUPERFAMILY SSF53041 4 138 5.23E-36 T 26-04-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4V04_RS07540 ef83d2626d924f45981af22213dcdf1c 900 Gene3D G3DSA:2.20.25.90 46 106 5.6E-19 T 26-04-2017 A4V04_RS07540 ef83d2626d924f45981af22213dcdf1c 900 Gene3D G3DSA:2.40.40.20 714 864 8.7E-36 T 26-04-2017 A4V04_RS07540 ef83d2626d924f45981af22213dcdf1c 900 SMART SM00926 49 103 7.3E-15 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS07540 ef83d2626d924f45981af22213dcdf1c 900 Gene3D G3DSA:3.40.228.10 369 508 1.5E-48 T 26-04-2017 A4V04_RS07540 ef83d2626d924f45981af22213dcdf1c 900 Gene3D G3DSA:3.40.228.10 219 303 1.5E-48 T 26-04-2017 A4V04_RS07540 ef83d2626d924f45981af22213dcdf1c 900 Pfam PF00384 Molybdopterin oxidoreductase 106 565 1.0E-38 T 26-04-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS07540 ef83d2626d924f45981af22213dcdf1c 900 Pfam PF01568 Molydopterin dinucleotide binding domain 738 842 4.7E-20 T 26-04-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4V04_RS07540 ef83d2626d924f45981af22213dcdf1c 900 SUPERFAMILY SSF50692 678 862 4.35E-35 T 26-04-2017 IPR009010 Aspartate decarboxylase-like domain A4V04_RS07540 ef83d2626d924f45981af22213dcdf1c 900 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 50 103 3.2E-13 T 26-04-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4V04_RS07540 ef83d2626d924f45981af22213dcdf1c 900 Gene3D G3DSA:3.40.50.740 509 562 1.4E-38 T 26-04-2017 A4V04_RS07540 ef83d2626d924f45981af22213dcdf1c 900 Gene3D G3DSA:3.40.50.740 108 192 1.4E-38 T 26-04-2017 A4V04_RS07540 ef83d2626d924f45981af22213dcdf1c 900 SUPERFAMILY SSF53706 47 567 1.28E-127 T 26-04-2017 A4V04_RS11650 4bf62121c5dc3b41df9aecd73322c8b2 314 Pfam PF01385 Probable transposase 85 189 1.7E-23 T 26-04-2017 IPR001959 Probable transposase, IS891/IS1136/IS1341 A4V04_RS11650 4bf62121c5dc3b41df9aecd73322c8b2 314 Pfam PF07282 Putative transposase DNA-binding domain 218 286 7.3E-21 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS11650 4bf62121c5dc3b41df9aecd73322c8b2 314 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 158 245 4.6E-8 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 Gene3D G3DSA:3.30.499.10 3 167 1.5E-19 T 26-04-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 Gene3D G3DSA:3.30.499.10 339 476 3.1E-57 T 26-04-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 PRINTS PR00415 Aconitase family signature 352 363 1.2E-43 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 PRINTS PR00415 Aconitase family signature 411 424 1.2E-43 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 PRINTS PR00415 Aconitase family signature 295 309 1.2E-43 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 PRINTS PR00415 Aconitase family signature 142 157 1.2E-43 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 PRINTS PR00415 Aconitase family signature 218 231 1.2E-43 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 PRINTS PR00415 Aconitase family signature 117 125 1.2E-43 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 PRINTS PR00415 Aconitase family signature 128 141 1.2E-43 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 PRINTS PR00415 Aconitase family signature 204 217 1.2E-43 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 ProSitePatterns PS01244 Aconitase family signature 2. 411 424 - T 26-04-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 Gene3D G3DSA:3.40.1060.10 176 289 2.3E-41 T 26-04-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 6 478 57.067 T 26-04-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 Pfam PF00330 Aconitase family (aconitate hydratase) 12 469 9.8E-147 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 7 477 6.2E-220 T 26-04-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A4V04_RS03470 4171f8017f52aae4a11ec8f2efe4b0d0 478 SUPERFAMILY SSF53732 6 476 2.35E-156 T 26-04-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS06230 afc871c9027a1110d07e4e1090abef09 793 SUPERFAMILY SSF52540 67 514 2.23E-54 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06230 afc871c9027a1110d07e4e1090abef09 793 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 68 517 4.1E-113 T 26-04-2017 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 A4V04_RS06230 afc871c9027a1110d07e4e1090abef09 793 Gene3D G3DSA:3.40.50.300 61 173 8.2E-56 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06230 afc871c9027a1110d07e4e1090abef09 793 Gene3D G3DSA:3.40.50.300 312 511 8.2E-56 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07385 c1fd51979948488f4210c41de549a8e6 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 4.5E-21 T 26-04-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07385 c1fd51979948488f4210c41de549a8e6 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 147 2.3E-25 T 26-04-2017 IPR020069 Ribosomal protein L9, C-terminal A4V04_RS07385 c1fd51979948488f4210c41de549a8e6 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 26-04-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07385 c1fd51979948488f4210c41de549a8e6 149 Gene3D G3DSA:3.10.430.100 61 148 3.7E-27 T 26-04-2017 IPR020069 Ribosomal protein L9, C-terminal A4V04_RS07385 c1fd51979948488f4210c41de549a8e6 149 SUPERFAMILY SSF55653 60 148 3.14E-25 T 26-04-2017 IPR020069 Ribosomal protein L9, C-terminal A4V04_RS07385 c1fd51979948488f4210c41de549a8e6 149 Gene3D G3DSA:3.40.5.10 1 52 4.5E-23 T 26-04-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS07385 c1fd51979948488f4210c41de549a8e6 149 SUPERFAMILY SSF55658 1 56 6.45E-17 T 26-04-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal A4V04_RS07385 c1fd51979948488f4210c41de549a8e6 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 148 1.1E-43 T 26-04-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS07385 c1fd51979948488f4210c41de549a8e6 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.194 T 26-04-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 231 247 - T 26-04-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 8 286 2.1E-104 T 26-04-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 289 1.0E-10 T 26-04-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 Gene3D G3DSA:3.40.190.10 3 110 1.6E-47 T 26-04-2017 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 PIRSF PIRSF001438 1 310 7.1E-112 T 26-04-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 7 213 3.2E-75 T 26-04-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 SUPERFAMILY SSF54782 220 308 8.63E-23 T 26-04-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 5 309 36.036 T 26-04-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 Gene3D G3DSA:3.30.160.40 222 306 2.4E-19 T 26-04-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 PRINTS PR00151 Porphobilinogen deaminase signature 45 65 4.4E-44 T 26-04-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 PRINTS PR00151 Porphobilinogen deaminase signature 124 141 4.4E-44 T 26-04-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 PRINTS PR00151 Porphobilinogen deaminase signature 143 160 4.4E-44 T 26-04-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 PRINTS PR00151 Porphobilinogen deaminase signature 230 247 4.4E-44 T 26-04-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 PRINTS PR00151 Porphobilinogen deaminase signature 76 95 4.4E-44 T 26-04-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 SUPERFAMILY SSF53850 5 218 2.39E-81 T 26-04-2017 A4V04_RS00910 2eb198da438b934c42702ae946a6849b 310 Gene3D G3DSA:3.40.190.10 111 199 1.9E-36 T 26-04-2017 A4V04_RS07065 c5a90827a79265c7cef32cbf6d021940 185 Pfam PF12682 Flavodoxin 31 157 5.2E-10 T 26-04-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A4V04_RS07065 c5a90827a79265c7cef32cbf6d021940 185 Gene3D G3DSA:3.40.50.360 30 158 2.4E-12 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS07065 c5a90827a79265c7cef32cbf6d021940 185 SUPERFAMILY SSF52218 28 155 5.43E-15 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 SUPERFAMILY SSF52029 185 376 2.54E-84 T 26-04-2017 IPR027409 GroEL-like apical domain A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 Gene3D G3DSA:3.50.7.10 189 367 1.4E-100 T 26-04-2017 IPR027409 GroEL-like apical domain A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 SUPERFAMILY SSF54849 137 202 1.9E-25 T 26-04-2017 A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 527 4.0E-258 T 26-04-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 26-04-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 PRINTS PR00298 60kDa chaperonin signature 83 110 2.5E-74 T 26-04-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 PRINTS PR00298 60kDa chaperonin signature 398 419 2.5E-74 T 26-04-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 PRINTS PR00298 60kDa chaperonin signature 27 53 2.5E-74 T 26-04-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 PRINTS PR00298 60kDa chaperonin signature 350 375 2.5E-74 T 26-04-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 PRINTS PR00298 60kDa chaperonin signature 268 291 2.5E-74 T 26-04-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 SUPERFAMILY SSF48592 406 521 2.75E-78 T 26-04-2017 A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 SUPERFAMILY SSF48592 7 134 2.75E-78 T 26-04-2017 A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 Gene3D G3DSA:1.10.560.10 4 188 2.0E-49 T 26-04-2017 IPR027413 GroEL-like equatorial domain A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 Gene3D G3DSA:1.10.560.10 368 518 2.4E-42 T 26-04-2017 IPR027413 GroEL-like equatorial domain A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 Hamap MF_00600 60 kDa chaperonin [groL]. 2 543 41.66 T 26-04-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4V04_RS12205 d7fe3bb9b4765df1257388aa2041d179 544 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 523 2.7E-100 T 26-04-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A4V04_RS02460 b1b14347c5ee4e60400cc20cde93958b 152 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 13 145 5.7E-14 T 26-04-2017 IPR009936 Protein of unknown function DUF1468 A4V04_RS05550 6517e4a3cff60176f06d9f6029fae5b8 463 SUPERFAMILY SSF56672 47 395 4.89E-45 T 26-04-2017 A4V04_RS05550 6517e4a3cff60176f06d9f6029fae5b8 463 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 109 318 1.0E-42 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS05550 6517e4a3cff60176f06d9f6029fae5b8 463 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 53 402 7.3E-114 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS05550 6517e4a3cff60176f06d9f6029fae5b8 463 Pfam PF08388 Group II intron, maturase-specific domain 338 412 6.1E-13 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS00760 8facc82c273c7d4da9ec63176cb2d2a7 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 214 8.9E-75 T 26-04-2017 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 A4V04_RS00760 8facc82c273c7d4da9ec63176cb2d2a7 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 26-04-2017 A4V04_RS00760 8facc82c273c7d4da9ec63176cb2d2a7 217 Hamap MF_00235 Adenylate kinase [adk]. 1 216 53.479 T 26-04-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4V04_RS00760 8facc82c273c7d4da9ec63176cb2d2a7 217 Pfam PF00406 Adenylate kinase 5 185 2.2E-58 T 26-04-2017 A4V04_RS00760 8facc82c273c7d4da9ec63176cb2d2a7 217 SUPERFAMILY SSF52540 1 215 5.66E-46 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00760 8facc82c273c7d4da9ec63176cb2d2a7 217 Pfam PF05191 Adenylate kinase, active site lid 123 158 1.3E-16 T 26-04-2017 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 A4V04_RS00760 8facc82c273c7d4da9ec63176cb2d2a7 217 Gene3D G3DSA:3.40.50.300 1 214 5.6E-82 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00760 8facc82c273c7d4da9ec63176cb2d2a7 217 PRINTS PR00094 Adenylate kinase signature 81 97 1.0E-35 T 26-04-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4V04_RS00760 8facc82c273c7d4da9ec63176cb2d2a7 217 PRINTS PR00094 Adenylate kinase signature 4 17 1.0E-35 T 26-04-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4V04_RS00760 8facc82c273c7d4da9ec63176cb2d2a7 217 PRINTS PR00094 Adenylate kinase signature 156 171 1.0E-35 T 26-04-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4V04_RS00760 8facc82c273c7d4da9ec63176cb2d2a7 217 PRINTS PR00094 Adenylate kinase signature 173 187 1.0E-35 T 26-04-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4V04_RS00760 8facc82c273c7d4da9ec63176cb2d2a7 217 PRINTS PR00094 Adenylate kinase signature 32 46 1.0E-35 T 26-04-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4V04_RS10850 bbed085b0d564cd104d9540c3c2f3cc5 48 Pfam PF08085 Entericidin EcnA/B family 21 37 4.0E-7 T 26-04-2017 IPR012556 Entericidin A/B GO:0009636|GO:0016020 A4V04_RS02175 0b26fa1993d3bdd18e8cc3e248b48dec 1264 SUPERFAMILY SSF52467 21 229 8.88E-9 T 26-04-2017 IPR029035 DHS-like NAD/FAD-binding domain A4V04_RS02175 0b26fa1993d3bdd18e8cc3e248b48dec 1264 Pfam PF13289 SIR2-like domain 123 270 2.8E-17 T 26-04-2017 A4V04_RS02175 0b26fa1993d3bdd18e8cc3e248b48dec 1264 Gene3D G3DSA:3.40.50.1220 103 147 1.1E-7 T 26-04-2017 IPR029035 DHS-like NAD/FAD-binding domain A4V04_RS02175 0b26fa1993d3bdd18e8cc3e248b48dec 1264 Gene3D G3DSA:3.40.50.1220 195 220 1.1E-7 T 26-04-2017 IPR029035 DHS-like NAD/FAD-binding domain A4V04_RS02175 0b26fa1993d3bdd18e8cc3e248b48dec 1264 Gene3D G3DSA:3.40.50.1220 20 36 1.1E-7 T 26-04-2017 IPR029035 DHS-like NAD/FAD-binding domain A4V04_RS06175 cae457e9d136ca2fbcc0450a5d27e253 438 SUPERFAMILY SSF56349 106 424 1.24E-30 T 26-04-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4V04_RS06175 cae457e9d136ca2fbcc0450a5d27e253 438 Gene3D G3DSA:1.10.443.10 236 412 7.9E-12 T 26-04-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS06175 cae457e9d136ca2fbcc0450a5d27e253 438 Pfam PF13356 Domain of unknown function (DUF4102) 5 86 1.2E-13 T 26-04-2017 IPR025166 Domain of unknown function DUF4102 A4V04_RS06175 cae457e9d136ca2fbcc0450a5d27e253 438 Gene3D G3DSA:1.10.150.130 107 201 1.2E-6 T 26-04-2017 IPR023109 Integrase/recombinase, N-terminal A4V04_RS01630 705c2e6debad2f86a485356e8c6c6bee 325 Pfam PF03466 LysR substrate binding domain 92 281 4.4E-17 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS01630 705c2e6debad2f86a485356e8c6c6bee 325 Gene3D G3DSA:3.40.190.10 94 230 2.6E-10 T 26-04-2017 A4V04_RS01630 705c2e6debad2f86a485356e8c6c6bee 325 SUPERFAMILY SSF53850 94 284 3.1E-17 T 26-04-2017 A4V04_RS01630 705c2e6debad2f86a485356e8c6c6bee 325 SUPERFAMILY SSF46785 11 114 8.46E-16 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01630 705c2e6debad2f86a485356e8c6c6bee 325 Gene3D G3DSA:1.10.10.10 13 90 6.2E-18 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01630 705c2e6debad2f86a485356e8c6c6bee 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 66 2.0E-12 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09420 7c05c913e588baa21df0e645d7bba52e 249 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 246 5.2E-120 T 26-04-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 A4V04_RS09420 7c05c913e588baa21df0e645d7bba52e 249 Gene3D G3DSA:3.40.50.1240 1 247 2.0E-100 T 26-04-2017 IPR029033 Histidine phosphatase superfamily A4V04_RS09420 7c05c913e588baa21df0e645d7bba52e 249 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 26-04-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 A4V04_RS09420 7c05c913e588baa21df0e645d7bba52e 249 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 46.344 T 26-04-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 A4V04_RS09420 7c05c913e588baa21df0e645d7bba52e 249 SMART SM00855 3 189 1.4E-26 T 26-04-2017 IPR013078 Histidine phosphatase superfamily, clade-1 A4V04_RS09420 7c05c913e588baa21df0e645d7bba52e 249 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 128 9.3E-32 T 26-04-2017 IPR013078 Histidine phosphatase superfamily, clade-1 A4V04_RS09420 7c05c913e588baa21df0e645d7bba52e 249 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 143 221 2.5E-5 T 26-04-2017 IPR013078 Histidine phosphatase superfamily, clade-1 A4V04_RS09420 7c05c913e588baa21df0e645d7bba52e 249 SUPERFAMILY SSF53254 1 245 8.25E-79 T 26-04-2017 IPR029033 Histidine phosphatase superfamily A4V04_RS09960 189fbaf024330a95da875347368f8d76 250 Gene3D G3DSA:1.10.10.60 171 233 4.2E-9 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS09960 189fbaf024330a95da875347368f8d76 250 Pfam PF00072 Response regulator receiver domain 4 113 4.7E-26 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS09960 189fbaf024330a95da875347368f8d76 250 Gene3D G3DSA:3.40.50.2300 2 123 6.4E-32 T 26-04-2017 A4V04_RS09960 189fbaf024330a95da875347368f8d76 250 SUPERFAMILY SSF52172 3 125 1.85E-34 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS09960 189fbaf024330a95da875347368f8d76 250 SMART SM00448 2 113 5.4E-30 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS09960 189fbaf024330a95da875347368f8d76 250 SUPERFAMILY SSF46689 167 233 4.48E-11 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS09960 189fbaf024330a95da875347368f8d76 250 Pfam PF02954 Bacterial regulatory protein, Fis family 190 230 1.0E-4 T 26-04-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4V04_RS05325 35ce946cf9808619ebaac0b7f80a6aed 87 SUPERFAMILY SSF46992 3 86 2.49E-26 T 26-04-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS05325 35ce946cf9808619ebaac0b7f80a6aed 87 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 13 86 1.0E-16 T 26-04-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS05325 35ce946cf9808619ebaac0b7f80a6aed 87 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 15.369 T 26-04-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS05325 35ce946cf9808619ebaac0b7f80a6aed 87 Gene3D G3DSA:1.20.58.110 1 86 1.1E-26 T 26-04-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS05325 35ce946cf9808619ebaac0b7f80a6aed 87 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 3.8E-22 T 26-04-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS05325 35ce946cf9808619ebaac0b7f80a6aed 87 Pfam PF01649 Ribosomal protein S20 2 84 8.1E-24 T 26-04-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS03505 3bfa9a39007f5566663daf9972b9c084 363 SUPERFAMILY SSF110997 287 357 9.68E-13 T 26-04-2017 IPR007730 Sporulation-related domain GO:0042834 A4V04_RS03505 3bfa9a39007f5566663daf9972b9c084 363 Gene3D G3DSA:3.30.70.1070 284 358 4.2E-14 T 26-04-2017 IPR007730 Sporulation-related domain GO:0042834 A4V04_RS03505 3bfa9a39007f5566663daf9972b9c084 363 Pfam PF05036 Sporulation related domain 286 350 1.0E-15 T 26-04-2017 IPR007730 Sporulation-related domain GO:0042834 A4V04_RS08080 dd9af9862962eec7889cdef2c133eaea 368 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 269 8.8E-10 T 26-04-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A4V04_RS08080 dd9af9862962eec7889cdef2c133eaea 368 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 357 3.4E-74 T 26-04-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 A4V04_RS08080 dd9af9862962eec7889cdef2c133eaea 368 SUPERFAMILY SSF111369 50 284 3.14E-50 T 26-04-2017 A4V04_RS08080 dd9af9862962eec7889cdef2c133eaea 368 Gene3D G3DSA:2.40.50.100 170 200 8.5E-20 T 26-04-2017 A4V04_RS08080 dd9af9862962eec7889cdef2c133eaea 368 Gene3D G3DSA:2.40.50.100 62 95 8.5E-20 T 26-04-2017 A4V04_RS01365 6d742e5da8cd4995a8f7bddb99d5a801 178 Gene3D G3DSA:1.10.3290.10 4 177 2.8E-58 T 26-04-2017 IPR003812 Fido domain A4V04_RS01365 6d742e5da8cd4995a8f7bddb99d5a801 178 SUPERFAMILY SSF140931 9 176 1.26E-38 T 26-04-2017 IPR003812 Fido domain A4V04_RS01365 6d742e5da8cd4995a8f7bddb99d5a801 178 Pfam PF02661 Fic/DOC family 30 115 2.1E-12 T 26-04-2017 IPR003812 Fido domain A4V04_RS04940 81549d4a0ee29b40f6a723881ed7d453 429 Pfam PF00171 Aldehyde dehydrogenase family 4 286 1.9E-16 T 26-04-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4V04_RS04940 81549d4a0ee29b40f6a723881ed7d453 429 Pfam PF00171 Aldehyde dehydrogenase family 320 385 1.6E-5 T 26-04-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4V04_RS04940 81549d4a0ee29b40f6a723881ed7d453 429 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 335 357 - T 26-04-2017 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4V04_RS04940 81549d4a0ee29b40f6a723881ed7d453 429 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 20 418 9.6E-149 T 26-04-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4V04_RS04940 81549d4a0ee29b40f6a723881ed7d453 429 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 12 428 39.904 T 26-04-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4V04_RS04940 81549d4a0ee29b40f6a723881ed7d453 429 Gene3D G3DSA:3.40.309.10 233 386 1.5E-38 T 26-04-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4V04_RS04940 81549d4a0ee29b40f6a723881ed7d453 429 SUPERFAMILY SSF53720 10 428 1.96E-109 T 26-04-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4V04_RS04940 81549d4a0ee29b40f6a723881ed7d453 429 Gene3D G3DSA:3.40.605.10 5 231 8.7E-96 T 26-04-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4V04_RS04940 81549d4a0ee29b40f6a723881ed7d453 429 Gene3D G3DSA:3.40.605.10 387 428 8.7E-96 T 26-04-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4V04_RS04940 81549d4a0ee29b40f6a723881ed7d453 429 PIRSF PIRSF000151 5 429 1.4E-168 T 26-04-2017 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A4V04_RS00780 2c30db5c4eebffbec4f6ba4130caeb9f 610 Pfam PF02601 Exonuclease VII, large subunit 130 398 1.7E-63 T 26-04-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 A4V04_RS00780 2c30db5c4eebffbec4f6ba4130caeb9f 610 Pfam PF02601 Exonuclease VII, large subunit 438 600 1.4E-10 T 26-04-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 A4V04_RS00780 2c30db5c4eebffbec4f6ba4130caeb9f 610 Pfam PF13742 OB-fold nucleic acid binding domain 14 106 8.8E-21 T 26-04-2017 IPR025824 OB-fold nucleic acid binding domain GO:0003676 A4V04_RS00780 2c30db5c4eebffbec4f6ba4130caeb9f 610 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 15 354 3.2E-99 T 26-04-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A4V04_RS00780 2c30db5c4eebffbec4f6ba4130caeb9f 610 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 8 603 23.004 T 26-04-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1308 19.704 T 26-04-2017 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 SUPERFAMILY SSF56042 838 1027 5.53E-45 T 26-04-2017 IPR010918 AIR synthase-related protein, C-terminal domain A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 SMART SM01211 1056 1307 8.2E-116 T 26-04-2017 A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 SUPERFAMILY SSF109736 157 221 2.35E-22 T 26-04-2017 A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 Gene3D G3DSA:3.30.1330.10 212 436 2.6E-38 T 26-04-2017 IPR016188 PurM-like, N-terminal domain A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 Gene3D G3DSA:3.30.1330.10 659 823 3.4E-14 T 26-04-2017 IPR016188 PurM-like, N-terminal domain A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 SUPERFAMILY SSF52317 1054 1307 1.43E-81 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 SUPERFAMILY SSF56042 447 669 2.69E-53 T 26-04-2017 IPR010918 AIR synthase-related protein, C-terminal domain A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 SUPERFAMILY SSF55326 644 829 1.99E-56 T 26-04-2017 A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 Gene3D G3DSA:3.90.650.10 511 605 0.001 T 26-04-2017 IPR010918 AIR synthase-related protein, C-terminal domain A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 Pfam PF02769 AIR synthase related protein, C-terminal domain 448 603 1.4E-29 T 26-04-2017 IPR010918 AIR synthase-related protein, C-terminal domain A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 Pfam PF02769 AIR synthase related protein, C-terminal domain 849 985 3.1E-13 T 26-04-2017 IPR010918 AIR synthase-related protein, C-terminal domain A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 SUPERFAMILY SSF55326 222 439 2.58E-53 T 26-04-2017 A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 Gene3D G3DSA:3.40.50.880 1056 1279 3.1E-9 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1056 1306 6.1E-89 T 26-04-2017 A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 SUPERFAMILY SSF82697 2 151 8.37E-39 T 26-04-2017 A4V04_RS08845 413a0bda2e127306a3dd2e3007c2ba89 1308 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 6 1307 0.0 T 26-04-2017 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4V04_RS13000 b4717e5e29f1f8c186bc41a1601185cf 1224 SMART SM00490 1077 1161 2.0E-23 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS13000 b4717e5e29f1f8c186bc41a1601185cf 1224 Pfam PF12419 SNF2 Helicase protein 586 713 1.3E-20 T 26-04-2017 IPR022138 Helicase SWF/SNF-related A4V04_RS13000 b4717e5e29f1f8c186bc41a1601185cf 1224 Pfam PF00271 Helicase conserved C-terminal domain 1048 1161 1.4E-17 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS13000 b4717e5e29f1f8c186bc41a1601185cf 1224 Gene3D G3DSA:3.40.50.300 1046 1195 4.9E-24 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13000 b4717e5e29f1f8c186bc41a1601185cf 1224 Pfam PF04434 SWIM zinc finger 127 145 1.5E-5 T 26-04-2017 IPR007527 Zinc finger, SWIM-type GO:0008270 A4V04_RS13000 b4717e5e29f1f8c186bc41a1601185cf 1224 Pfam PF00176 SNF2 family N-terminal domain 773 1032 2.4E-46 T 26-04-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 A4V04_RS13000 b4717e5e29f1f8c186bc41a1601185cf 1224 Gene3D G3DSA:3.40.50.300 747 917 2.9E-27 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13000 b4717e5e29f1f8c186bc41a1601185cf 1224 SUPERFAMILY SSF52540 966 1218 1.45E-63 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13000 b4717e5e29f1f8c186bc41a1601185cf 1224 SMART SM00487 751 942 7.4E-31 T 26-04-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4V04_RS13000 b4717e5e29f1f8c186bc41a1601185cf 1224 SUPERFAMILY SSF52540 738 962 8.75E-51 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07170 b1dac0c298df33652304ade58a6c6c1e 507 SUPERFAMILY SSF56425 299 446 1.05E-20 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS07170 b1dac0c298df33652304ade58a6c6c1e 507 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 7 26 3.2E-4 T 26-04-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A4V04_RS07170 b1dac0c298df33652304ade58a6c6c1e 507 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 40 499 4.1E-91 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS07170 b1dac0c298df33652304ade58a6c6c1e 507 Pfam PF00890 FAD binding domain 40 486 1.4E-56 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS07170 b1dac0c298df33652304ade58a6c6c1e 507 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 62 3.9E-6 T 26-04-2017 A4V04_RS07170 b1dac0c298df33652304ade58a6c6c1e 507 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 463 478 3.9E-6 T 26-04-2017 A4V04_RS07170 b1dac0c298df33652304ade58a6c6c1e 507 Gene3D G3DSA:3.90.700.10 302 419 2.1E-19 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS07170 b1dac0c298df33652304ade58a6c6c1e 507 SUPERFAMILY SSF51905 445 503 2.06E-45 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07170 b1dac0c298df33652304ade58a6c6c1e 507 SUPERFAMILY SSF51905 25 310 2.06E-45 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07170 b1dac0c298df33652304ade58a6c6c1e 507 Gene3D G3DSA:3.50.50.60 442 504 5.1E-72 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07170 b1dac0c298df33652304ade58a6c6c1e 507 Gene3D G3DSA:3.50.50.60 29 285 5.1E-72 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS00855 313314c61abcddb0147dad573481067a 319 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 282 4.9E-101 T 26-04-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 A4V04_RS00855 313314c61abcddb0147dad573481067a 319 Gene3D G3DSA:3.40.50.1400 63 151 5.9E-4 T 26-04-2017 A4V04_RS00855 313314c61abcddb0147dad573481067a 319 Pfam PF02401 LytB protein 3 280 8.3E-94 T 26-04-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 A4V04_RS00855 313314c61abcddb0147dad573481067a 319 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 283 38.238 T 26-04-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 A4V04_RS03600 e3d823df78bedd9e3cdea836de0294e2 248 Pfam PF01012 Electron transfer flavoprotein domain 24 203 1.2E-39 T 26-04-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4V04_RS03600 e3d823df78bedd9e3cdea836de0294e2 248 SMART SM00893 22 210 8.3E-53 T 26-04-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4V04_RS03600 e3d823df78bedd9e3cdea836de0294e2 248 Gene3D G3DSA:3.40.50.620 1 246 1.0E-88 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS03600 e3d823df78bedd9e3cdea836de0294e2 248 PIRSF PIRSF000090 1 248 2.2E-71 T 26-04-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 A4V04_RS03600 e3d823df78bedd9e3cdea836de0294e2 248 SUPERFAMILY SSF52402 1 241 7.67E-71 T 26-04-2017 A4V04_RS06760 98d244713a27a56434028c30e6567832 147 SUPERFAMILY SSF82093 29 134 1.7E-40 T 26-04-2017 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 A4V04_RS06760 98d244713a27a56434028c30e6567832 147 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 139 32.499 T 26-04-2017 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 A4V04_RS06760 98d244713a27a56434028c30e6567832 147 Gene3D G3DSA:2.40.50.140 25 123 1.0E-37 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS06760 98d244713a27a56434028c30e6567832 147 Pfam PF03100 CcmE 4 129 5.8E-49 T 26-04-2017 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 A4V04_RS09515 a635e4b6752f85faed3bca86247a232b 316 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 48 311 2.3E-78 T 26-04-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 A4V04_RS09515 a635e4b6752f85faed3bca86247a232b 316 Gene3D G3DSA:1.10.3720.10 47 311 6.5E-41 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS09515 a635e4b6752f85faed3bca86247a232b 316 SUPERFAMILY SSF161098 45 307 5.98E-38 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS09515 a635e4b6752f85faed3bca86247a232b 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 304 3.0E-21 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS12210 c39b8c84989735d094cf4479a762cde7 95 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 27.054 T 26-04-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4V04_RS12210 c39b8c84989735d094cf4479a762cde7 95 SMART SM00883 2 94 1.5E-59 T 26-04-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4V04_RS12210 c39b8c84989735d094cf4479a762cde7 95 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 1.4E-37 T 26-04-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4V04_RS12210 c39b8c84989735d094cf4479a762cde7 95 PRINTS PR00297 10kDa chaperonin signature 60 72 3.5E-33 T 26-04-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4V04_RS12210 c39b8c84989735d094cf4479a762cde7 95 PRINTS PR00297 10kDa chaperonin signature 3 18 3.5E-33 T 26-04-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4V04_RS12210 c39b8c84989735d094cf4479a762cde7 95 PRINTS PR00297 10kDa chaperonin signature 25 46 3.5E-33 T 26-04-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4V04_RS12210 c39b8c84989735d094cf4479a762cde7 95 PRINTS PR00297 10kDa chaperonin signature 81 94 3.5E-33 T 26-04-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4V04_RS12210 c39b8c84989735d094cf4479a762cde7 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 26-04-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 A4V04_RS12210 c39b8c84989735d094cf4479a762cde7 95 Gene3D G3DSA:2.30.33.40 1 95 4.1E-41 T 26-04-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4V04_RS12210 c39b8c84989735d094cf4479a762cde7 95 SUPERFAMILY SSF50129 1 95 4.17E-36 T 26-04-2017 IPR011032 GroES-like A4V04_RS00755 b815d1e8113049f4e2352baf3cf849b1 339 Gene3D G3DSA:3.90.25.10 181 233 6.9E-52 T 26-04-2017 A4V04_RS00755 b815d1e8113049f4e2352baf3cf849b1 339 Gene3D G3DSA:3.90.25.10 265 339 6.9E-52 T 26-04-2017 A4V04_RS00755 b815d1e8113049f4e2352baf3cf849b1 339 Gene3D G3DSA:3.40.50.720 2 180 1.0E-53 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS00755 b815d1e8113049f4e2352baf3cf849b1 339 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 326 1.8E-57 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS00755 b815d1e8113049f4e2352baf3cf849b1 339 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 336 7.4E-126 T 26-04-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 A4V04_RS00755 b815d1e8113049f4e2352baf3cf849b1 339 SUPERFAMILY SSF51735 1 338 7.84E-97 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS08305 02353c8d059291fc2b51435409efb78d 475 Pfam PF01266 FAD dependent oxidoreductase 25 321 9.3E-22 T 26-04-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4V04_RS08305 02353c8d059291fc2b51435409efb78d 475 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 24 36 4.5E-18 T 26-04-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4V04_RS08305 02353c8d059291fc2b51435409efb78d 475 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 364 376 4.5E-18 T 26-04-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4V04_RS08305 02353c8d059291fc2b51435409efb78d 475 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 37 47 4.5E-18 T 26-04-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4V04_RS08305 02353c8d059291fc2b51435409efb78d 475 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 99 111 4.5E-18 T 26-04-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4V04_RS08305 02353c8d059291fc2b51435409efb78d 475 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 53 65 4.5E-18 T 26-04-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4V04_RS08305 02353c8d059291fc2b51435409efb78d 475 SUPERFAMILY SSF51905 14 273 2.49E-23 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS08305 02353c8d059291fc2b51435409efb78d 475 Gene3D G3DSA:3.50.50.60 19 246 1.2E-27 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02070 8d5dc99c9c7a44cd2c369308e66118bb 69 Pfam PF05717 IS66 Orf2 like protein 2 66 4.1E-9 T 26-04-2017 IPR008878 Transposase IS66, Orf2 A4V04_RS01440 46e6d5cc5b8e83893117516e4e1dd495 443 Pfam PF13356 Domain of unknown function (DUF4102) 8 90 3.3E-12 T 26-04-2017 IPR025166 Domain of unknown function DUF4102 A4V04_RS01440 46e6d5cc5b8e83893117516e4e1dd495 443 Pfam PF00589 Phage integrase family 235 360 2.0E-5 T 26-04-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS01440 46e6d5cc5b8e83893117516e4e1dd495 443 Gene3D G3DSA:1.10.150.130 111 207 2.1E-9 T 26-04-2017 IPR023109 Integrase/recombinase, N-terminal A4V04_RS01440 46e6d5cc5b8e83893117516e4e1dd495 443 SUPERFAMILY SSF56349 110 430 7.65E-33 T 26-04-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4V04_RS01440 46e6d5cc5b8e83893117516e4e1dd495 443 Gene3D G3DSA:1.10.443.10 235 426 3.0E-8 T 26-04-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 SUPERFAMILY SSF54814 212 288 7.19E-29 T 26-04-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 SUPERFAMILY SSF69705 1 132 2.75E-25 T 26-04-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 352 2.0E-102 T 26-04-2017 IPR010213 Transcription termination factor NusA GO:0003723 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 Gene3D G3DSA:2.40.50.140 147 208 1.0E-17 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 SMART SM00316 144 210 1.5E-7 T 26-04-2017 IPR022967 RNA-binding domain, S1 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 SUPERFAMILY SSF47794 364 425 2.67E-13 T 26-04-2017 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 Gene3D G3DSA:3.30.300.20 289 357 4.2E-22 T 26-04-2017 IPR015946 K homology domain-like, alpha/beta A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 Pfam PF14520 Helix-hairpin-helix domain 375 421 7.6E-4 T 26-04-2017 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 Pfam PF14520 Helix-hairpin-helix domain 442 494 6.3E-6 T 26-04-2017 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 SUPERFAMILY SSF50249 144 209 6.29E-13 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 Gene3D G3DSA:3.30.1480.10 1 132 5.1E-31 T 26-04-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 SUPERFAMILY SSF47794 441 498 3.77E-11 T 26-04-2017 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 Gene3D G3DSA:1.10.150.20 368 421 4.4E-17 T 26-04-2017 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 Pfam PF08529 NusA N-terminal domain 5 132 7.3E-28 T 26-04-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 420 25.461 T 26-04-2017 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 Gene3D G3DSA:3.30.300.20 210 287 5.5E-34 T 26-04-2017 IPR015946 K homology domain-like, alpha/beta A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 SUPERFAMILY SSF54814 290 352 1.83E-10 T 26-04-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 Pfam PF13184 NusA-like KH domain 240 307 1.1E-25 T 26-04-2017 IPR025249 KH domain, NusA-like GO:0003723 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 Gene3D G3DSA:1.10.150.20 441 497 2.3E-17 T 26-04-2017 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 SMART SM00322 240 303 5.9 T 26-04-2017 IPR004087 K Homology domain GO:0003676 A4V04_RS02715 81eb25251f4556a8115ee1b00c27579e 499 SMART SM00322 311 384 0.36 T 26-04-2017 IPR004087 K Homology domain GO:0003676 A4V04_RS04920 c78d27cf26a8930769f56c76825f9615 783 Pfam PF00580 UvrD/REP helicase N-terminal domain 9 275 3.0E-67 T 26-04-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 A4V04_RS04920 c78d27cf26a8930769f56c76825f9615 783 Gene3D G3DSA:1.10.486.10 392 544 4.6E-37 T 26-04-2017 A4V04_RS04920 c78d27cf26a8930769f56c76825f9615 783 Gene3D G3DSA:3.40.50.300 556 647 1.3E-67 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04920 c78d27cf26a8930769f56c76825f9615 783 Gene3D G3DSA:3.40.50.300 290 391 1.3E-67 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04920 c78d27cf26a8930769f56c76825f9615 783 Pfam PF13361 UvrD-like helicase C-terminal domain 281 620 4.3E-71 T 26-04-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4V04_RS04920 c78d27cf26a8930769f56c76825f9615 783 Gene3D G3DSA:1.10.10.160 113 188 2.0E-16 T 26-04-2017 IPR013986 DExx box DNA helicase domain A4V04_RS04920 c78d27cf26a8930769f56c76825f9615 783 Gene3D G3DSA:3.40.50.300 189 289 1.6E-63 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04920 c78d27cf26a8930769f56c76825f9615 783 Gene3D G3DSA:3.40.50.300 4 109 1.6E-63 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04920 c78d27cf26a8930769f56c76825f9615 783 SUPERFAMILY SSF52540 4 644 6.62E-160 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08520 ca0fb52fb9f192b2c5a090bf9aba5a53 144 SUPERFAMILY SSF52402 1 144 4.4E-37 T 26-04-2017 A4V04_RS08520 ca0fb52fb9f192b2c5a090bf9aba5a53 144 Gene3D G3DSA:3.40.50.620 1 144 2.0E-39 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS08520 ca0fb52fb9f192b2c5a090bf9aba5a53 144 Pfam PF00582 Universal stress protein family 1 144 1.2E-32 T 26-04-2017 IPR006016 UspA GO:0006950 A4V04_RS08520 ca0fb52fb9f192b2c5a090bf9aba5a53 144 PRINTS PR01438 Universal stress protein signature 104 116 6.0E-19 T 26-04-2017 IPR006015 Universal stress protein A A4V04_RS08520 ca0fb52fb9f192b2c5a090bf9aba5a53 144 PRINTS PR01438 Universal stress protein signature 2 20 6.0E-19 T 26-04-2017 IPR006015 Universal stress protein A A4V04_RS08520 ca0fb52fb9f192b2c5a090bf9aba5a53 144 PRINTS PR01438 Universal stress protein signature 122 144 6.0E-19 T 26-04-2017 IPR006015 Universal stress protein A A4V04_RS10660 57c9a5770ea91fccc40b5326e1a8b10b 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 13 156 1.0E-36 T 26-04-2017 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 A4V04_RS10660 57c9a5770ea91fccc40b5326e1a8b10b 156 SUPERFAMILY SSF81573 67 121 5.1E-8 T 26-04-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain A4V04_RS10660 57c9a5770ea91fccc40b5326e1a8b10b 156 Gene3D G3DSA:1.20.5.620 67 121 2.0E-14 T 26-04-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain A4V04_RS10660 57c9a5770ea91fccc40b5326e1a8b10b 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 156 11.291 T 26-04-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A4V04_RS10660 57c9a5770ea91fccc40b5326e1a8b10b 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 6.8E-24 T 26-04-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A4V04_RS07380 f7a388be38d90b636a9f9b48e1d062ad 596 Pfam PF01609 Transposase DDE domain 247 516 4.5E-12 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS07380 f7a388be38d90b636a9f9b48e1d062ad 596 SUPERFAMILY SSF53098 220 525 9.86E-7 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS03940 e8e4e36e9a64da3306f32730926da781 177 Gene3D G3DSA:1.10.10.10 84 164 4.7E-31 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS03940 e8e4e36e9a64da3306f32730926da781 177 SUPERFAMILY SSF53155 45 89 3.57E-9 T 26-04-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS03940 e8e4e36e9a64da3306f32730926da781 177 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 85 164 1.6E-33 T 26-04-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS03940 e8e4e36e9a64da3306f32730926da781 177 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 86 164 3.8E-28 T 26-04-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS03940 e8e4e36e9a64da3306f32730926da781 177 SUPERFAMILY SSF46767 84 165 6.15E-29 T 26-04-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS03940 e8e4e36e9a64da3306f32730926da781 177 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 135 141 - T 26-04-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4V04_RS03480 e9c0f33a2dc9f73155f9ec4f8b2a797f 358 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 352 1.2E-146 T 26-04-2017 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 A4V04_RS03480 e9c0f33a2dc9f73155f9ec4f8b2a797f 358 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 26-04-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A4V04_RS03480 e9c0f33a2dc9f73155f9ec4f8b2a797f 358 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 353 7.5E-133 T 26-04-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4V04_RS03480 e9c0f33a2dc9f73155f9ec4f8b2a797f 358 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 357 49.563 T 26-04-2017 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 A4V04_RS03480 e9c0f33a2dc9f73155f9ec4f8b2a797f 358 SMART SM01329 4 353 6.3E-206 T 26-04-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4V04_RS03480 e9c0f33a2dc9f73155f9ec4f8b2a797f 358 Gene3D G3DSA:3.40.718.10 1 358 3.2E-130 T 26-04-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4V04_RS03480 e9c0f33a2dc9f73155f9ec4f8b2a797f 358 SUPERFAMILY SSF53659 1 357 3.42E-121 T 26-04-2017 A4V04_RS01900 0fefa193775f79397325a1d1519f3dee 336 SUPERFAMILY SSF53448 5 271 2.77E-28 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS01900 0fefa193775f79397325a1d1519f3dee 336 Pfam PF00535 Glycosyl transferase family 2 9 175 1.5E-15 T 26-04-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4V04_RS01900 0fefa193775f79397325a1d1519f3dee 336 Gene3D G3DSA:3.90.550.10 6 251 2.6E-15 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS09590 272b769b4cac96ebe29331e73ff7d225 380 Gene3D G3DSA:2.40.160.10 21 380 4.2E-72 T 26-04-2017 IPR023614 Porin domain A4V04_RS09590 272b769b4cac96ebe29331e73ff7d225 380 PRINTS PR00184 Neisseria sp. porin signature 208 225 4.0E-6 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS09590 272b769b4cac96ebe29331e73ff7d225 380 PRINTS PR00184 Neisseria sp. porin signature 52 77 4.0E-6 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS09590 272b769b4cac96ebe29331e73ff7d225 380 PRINTS PR00184 Neisseria sp. porin signature 317 341 4.0E-6 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS09590 272b769b4cac96ebe29331e73ff7d225 380 Pfam PF13609 Gram-negative porin 9 344 2.3E-45 T 26-04-2017 A4V04_RS09590 272b769b4cac96ebe29331e73ff7d225 380 SUPERFAMILY SSF56935 22 380 5.19E-59 T 26-04-2017 A4V04_RS12665 9a99b87261b2518046948c7a185999fd 276 Gene3D G3DSA:1.25.40.10 40 226 2.4E-6 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS12665 9a99b87261b2518046948c7a185999fd 276 SUPERFAMILY SSF81901 44 219 8.72E-6 T 26-04-2017 A4V04_RS11935 9d5e556f8aa7a699640a5359ada53e90 203 Pfam PF01121 Dephospho-CoA kinase 2 177 3.4E-51 T 26-04-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 A4V04_RS11935 9d5e556f8aa7a699640a5359ada53e90 203 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 2 186 7.3E-45 T 26-04-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 A4V04_RS11935 9d5e556f8aa7a699640a5359ada53e90 203 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 191 23.397 T 26-04-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 A4V04_RS11935 9d5e556f8aa7a699640a5359ada53e90 203 Gene3D G3DSA:3.40.50.300 2 195 1.0E-58 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11935 9d5e556f8aa7a699640a5359ada53e90 203 SUPERFAMILY SSF52540 2 190 3.04E-32 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10430 4bc968bfb40d279bc8d194b80c2101cf 313 Pfam PF09084 NMT1/THI5 like 52 247 5.2E-25 T 26-04-2017 IPR015168 SsuA/THI5-like A4V04_RS10430 4bc968bfb40d279bc8d194b80c2101cf 313 Gene3D G3DSA:3.40.190.10 118 231 2.9E-17 T 26-04-2017 A4V04_RS10430 4bc968bfb40d279bc8d194b80c2101cf 313 SUPERFAMILY SSF53850 26 305 5.55E-39 T 26-04-2017 A4V04_RS01620 91fe61297076234ee0d381dec5074069 481 PRINTS PR00149 Fumarate lyase superfamily signature 319 335 7.4E-14 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01620 91fe61297076234ee0d381dec5074069 481 PRINTS PR00149 Fumarate lyase superfamily signature 273 300 7.4E-14 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01620 91fe61297076234ee0d381dec5074069 481 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 7.4E-14 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01620 91fe61297076234ee0d381dec5074069 481 PRINTS PR00149 Fumarate lyase superfamily signature 181 199 7.4E-14 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01620 91fe61297076234ee0d381dec5074069 481 Gene3D G3DSA:1.10.275.10 46 95 1.1E-5 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS01620 91fe61297076234ee0d381dec5074069 481 SUPERFAMILY SSF48557 51 445 2.2E-56 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS01620 91fe61297076234ee0d381dec5074069 481 ProSitePatterns PS00163 Fumarate lyases signature. 319 328 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS01620 91fe61297076234ee0d381dec5074069 481 Gene3D G3DSA:1.20.200.10 142 404 2.7E-52 T 26-04-2017 A4V04_RS01620 91fe61297076234ee0d381dec5074069 481 Pfam PF00206 Lyase 60 343 1.6E-42 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS04120 e6a0260ca3d76727eef1bd284d582811 329 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 4 183 3.7E-31 T 26-04-2017 IPR005126 NapC/NirT cytochrome c, N-terminal A4V04_RS04120 e6a0260ca3d76727eef1bd284d582811 329 SUPERFAMILY SSF48695 6 182 1.65E-17 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS04120 e6a0260ca3d76727eef1bd284d582811 329 Gene3D G3DSA:1.10.3820.10 4 184 3.2E-15 T 26-04-2017 A4V04_RS04650 9fc034fa65aced6e5683ac582c5668eb 398 Gene3D G3DSA:3.40.50.1100 114 390 1.7E-36 T 26-04-2017 A4V04_RS04650 9fc034fa65aced6e5683ac582c5668eb 398 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 24 391 1.5E-146 T 26-04-2017 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 A4V04_RS04650 9fc034fa65aced6e5683ac582c5668eb 398 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 36 376 5.5E-50 T 26-04-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4V04_RS04650 9fc034fa65aced6e5683ac582c5668eb 398 SUPERFAMILY SSF53686 34 355 5.37E-55 T 26-04-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4V04_RS10120 db0a3df705565b5b1af96ae67236e07b 417 PIRSF PIRSF037215 4 414 4.1E-156 T 26-04-2017 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 A4V04_RS10120 db0a3df705565b5b1af96ae67236e07b 417 Pfam PF01546 Peptidase family M20/M25/M40 145 407 1.8E-14 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS10120 db0a3df705565b5b1af96ae67236e07b 417 Gene3D G3DSA:3.30.70.360 216 325 2.0E-40 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS10120 db0a3df705565b5b1af96ae67236e07b 417 Pfam PF07687 Peptidase dimerisation domain 213 310 2.3E-10 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS10120 db0a3df705565b5b1af96ae67236e07b 417 SUPERFAMILY SSF55031 215 325 6.38E-32 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS10120 db0a3df705565b5b1af96ae67236e07b 417 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 79 88 - T 26-04-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A4V04_RS10120 db0a3df705565b5b1af96ae67236e07b 417 TIGRFAM TIGR01882 peptidase-T: peptidase T 5 410 1.8E-131 T 26-04-2017 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 A4V04_RS10120 db0a3df705565b5b1af96ae67236e07b 417 SUPERFAMILY SSF53187 328 408 2.77E-68 T 26-04-2017 A4V04_RS10120 db0a3df705565b5b1af96ae67236e07b 417 SUPERFAMILY SSF53187 7 216 2.77E-68 T 26-04-2017 A4V04_RS10120 db0a3df705565b5b1af96ae67236e07b 417 Gene3D G3DSA:3.40.630.10 8 215 7.5E-99 T 26-04-2017 A4V04_RS10120 db0a3df705565b5b1af96ae67236e07b 417 Gene3D G3DSA:3.40.630.10 328 409 7.5E-99 T 26-04-2017 A4V04_RS09385 f80944a8946407e9e4a066c0701242e0 458 Pfam PF03606 C4-dicarboxylate anaerobic carrier 5 452 1.3E-71 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS09385 f80944a8946407e9e4a066c0701242e0 458 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 55 448 4.6E-105 T 26-04-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A4V04_RS04815 a2ad88cb7817bcfff9ed7794ac1cb6d2 503 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 230 237 - T 26-04-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A4V04_RS04815 a2ad88cb7817bcfff9ed7794ac1cb6d2 503 PIRSF PIRSF036492 5 501 3.2E-145 T 26-04-2017 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 A4V04_RS04815 a2ad88cb7817bcfff9ed7794ac1cb6d2 503 Pfam PF00171 Aldehyde dehydrogenase family 43 457 1.7E-79 T 26-04-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4V04_RS04815 a2ad88cb7817bcfff9ed7794ac1cb6d2 503 Gene3D G3DSA:3.40.605.10 44 244 1.2E-44 T 26-04-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4V04_RS04815 a2ad88cb7817bcfff9ed7794ac1cb6d2 503 SUPERFAMILY SSF53720 42 481 1.44E-99 T 26-04-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4V04_RS04815 a2ad88cb7817bcfff9ed7794ac1cb6d2 503 Gene3D G3DSA:3.40.309.10 245 437 6.4E-47 T 26-04-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4V04_RS04815 a2ad88cb7817bcfff9ed7794ac1cb6d2 503 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 258 269 - T 26-04-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A4V04_RS01085 da7aabd9aa880086f1b8b11c7648098f 271 Pfam PF01925 Sulfite exporter TauE/SafE 9 263 2.9E-55 T 26-04-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 A4V04_RS01335 839342a18a9c3243a3c97b8afb9179f3 789 Gene3D G3DSA:3.40.50.2000 513 669 1.2E-12 T 26-04-2017 A4V04_RS01335 839342a18a9c3243a3c97b8afb9179f3 789 Pfam PF00535 Glycosyl transferase family 2 4 132 2.6E-21 T 26-04-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4V04_RS01335 839342a18a9c3243a3c97b8afb9179f3 789 Gene3D G3DSA:3.90.550.10 1 187 2.7E-33 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS01335 839342a18a9c3243a3c97b8afb9179f3 789 SUPERFAMILY SSF53756 334 677 9.42E-44 T 26-04-2017 A4V04_RS01335 839342a18a9c3243a3c97b8afb9179f3 789 SUPERFAMILY SSF53448 3 230 5.63E-33 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS01335 839342a18a9c3243a3c97b8afb9179f3 789 Pfam PF13439 Glycosyltransferase Family 4 345 493 9.5E-8 T 26-04-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4V04_RS01335 839342a18a9c3243a3c97b8afb9179f3 789 Pfam PF00534 Glycosyl transferases group 1 509 671 2.5E-21 T 26-04-2017 IPR001296 Glycosyl transferase, family 1 A4V04_RS04260 012d2881844ad854b0ea19f237e5bcc5 468 Pfam PF10415 Fumarase C C-terminus 409 462 4.0E-14 T 26-04-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS04260 012d2881844ad854b0ea19f237e5bcc5 468 PRINTS PR00149 Fumarate lyase superfamily signature 318 334 2.2E-28 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS04260 012d2881844ad854b0ea19f237e5bcc5 468 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 2.2E-28 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS04260 012d2881844ad854b0ea19f237e5bcc5 468 PRINTS PR00149 Fumarate lyase superfamily signature 272 299 2.2E-28 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS04260 012d2881844ad854b0ea19f237e5bcc5 468 PRINTS PR00149 Fumarate lyase superfamily signature 181 199 2.2E-28 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS04260 012d2881844ad854b0ea19f237e5bcc5 468 Gene3D G3DSA:1.10.40.30 409 466 2.8E-13 T 26-04-2017 A4V04_RS04260 012d2881844ad854b0ea19f237e5bcc5 468 PRINTS PR00145 Argininosuccinate lyase family signature 318 334 8.3E-7 T 26-04-2017 A4V04_RS04260 012d2881844ad854b0ea19f237e5bcc5 468 PRINTS PR00145 Argininosuccinate lyase family signature 135 157 8.3E-7 T 26-04-2017 A4V04_RS04260 012d2881844ad854b0ea19f237e5bcc5 468 PRINTS PR00145 Argininosuccinate lyase family signature 176 196 8.3E-7 T 26-04-2017 A4V04_RS04260 012d2881844ad854b0ea19f237e5bcc5 468 SUPERFAMILY SSF48557 2 462 1.62E-134 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS04260 012d2881844ad854b0ea19f237e5bcc5 468 Gene3D G3DSA:1.10.275.10 2 140 1.2E-47 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS04260 012d2881844ad854b0ea19f237e5bcc5 468 ProSitePatterns PS00163 Fumarate lyases signature. 318 327 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS04260 012d2881844ad854b0ea19f237e5bcc5 468 Pfam PF00206 Lyase 10 343 2.1E-92 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS04260 012d2881844ad854b0ea19f237e5bcc5 468 Gene3D G3DSA:1.20.200.10 141 403 8.3E-88 T 26-04-2017 A4V04_RS12760 4edaef4a02cae26049a26278e059afbd 215 Pfam PF01810 LysE type translocator 15 209 4.1E-23 T 26-04-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 A4V04_RS05935 4c0b39a104ebd6e672e2926ec6e8d4ef 248 Pfam PF01048 Phosphorylase superfamily 16 244 1.3E-32 T 26-04-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4V04_RS05935 4c0b39a104ebd6e672e2926ec6e8d4ef 248 SUPERFAMILY SSF53167 3 246 1.34E-60 T 26-04-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4V04_RS05935 4c0b39a104ebd6e672e2926ec6e8d4ef 248 Gene3D G3DSA:3.40.50.1580 5 245 1.6E-57 T 26-04-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4V04_RS04795 87ef4aea39aa0677766771564f785e22 168 Pfam PF00186 Dihydrofolate reductase 5 162 6.1E-61 T 26-04-2017 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A4V04_RS04795 87ef4aea39aa0677766771564f785e22 168 PRINTS PR00070 Dihydrofolate reductase signature 94 108 1.2E-16 T 26-04-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A4V04_RS04795 87ef4aea39aa0677766771564f785e22 168 PRINTS PR00070 Dihydrofolate reductase signature 30 38 1.2E-16 T 26-04-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A4V04_RS04795 87ef4aea39aa0677766771564f785e22 168 PRINTS PR00070 Dihydrofolate reductase signature 16 26 1.2E-16 T 26-04-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A4V04_RS04795 87ef4aea39aa0677766771564f785e22 168 PRINTS PR00070 Dihydrofolate reductase signature 43 54 1.2E-16 T 26-04-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A4V04_RS04795 87ef4aea39aa0677766771564f785e22 168 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 16 38 - T 26-04-2017 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-113510|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-69205 A4V04_RS04795 87ef4aea39aa0677766771564f785e22 168 Gene3D G3DSA:3.40.430.10 3 165 8.1E-64 T 26-04-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4V04_RS04795 87ef4aea39aa0677766771564f785e22 168 SUPERFAMILY SSF53597 4 163 1.44E-58 T 26-04-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4V04_RS04795 87ef4aea39aa0677766771564f785e22 168 PIRSF PIRSF000194 1 165 5.4E-63 T 26-04-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A4V04_RS12705 338db9a519a076c7bd4bbf46866e051d 157 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 4 148 5.3E-57 T 26-04-2017 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 A4V04_RS12705 338db9a519a076c7bd4bbf46866e051d 157 Pfam PF02470 MlaD protein 40 117 1.7E-23 T 26-04-2017 IPR003399 Mce/MlaD A4V04_RS01665 4ae048fb33536af6e4668c653448745b 327 SUPERFAMILY SSF48557 4 309 3.93E-50 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS01665 4ae048fb33536af6e4668c653448745b 327 Pfam PF00206 Lyase 3 161 1.3E-35 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS01665 4ae048fb33536af6e4668c653448745b 327 Gene3D G3DSA:1.20.200.10 3 267 5.5E-48 T 26-04-2017 A4V04_RS01665 4ae048fb33536af6e4668c653448745b 327 Gene3D G3DSA:1.10.40.30 268 312 1.1E-8 T 26-04-2017 A4V04_RS01665 4ae048fb33536af6e4668c653448745b 327 PRINTS PR00149 Fumarate lyase superfamily signature 28 46 1.5E-8 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01665 4ae048fb33536af6e4668c653448745b 327 PRINTS PR00149 Fumarate lyase superfamily signature 119 146 1.5E-8 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01665 4ae048fb33536af6e4668c653448745b 327 Pfam PF10415 Fumarase C C-terminus 259 310 1.6E-8 T 26-04-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4V04_RS03055 c163085f58ff3af9239d4e6aee121223 410 Pfam PF12698 ABC-2 family transporter protein 31 379 4.2E-26 T 26-04-2017 A4V04_RS04105 2ee18bea9f592881343f626a79e90f04 405 Gene3D G3DSA:3.20.20.70 98 308 9.5E-27 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS04105 2ee18bea9f592881343f626a79e90f04 405 Gene3D G3DSA:3.20.20.70 17 54 9.5E-27 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS04105 2ee18bea9f592881343f626a79e90f04 405 SUPERFAMILY SSF51412 109 340 2.14E-26 T 26-04-2017 A4V04_RS04105 2ee18bea9f592881343f626a79e90f04 405 SUPERFAMILY SSF51412 17 76 2.14E-26 T 26-04-2017 A4V04_RS04105 2ee18bea9f592881343f626a79e90f04 405 Pfam PF03060 Nitronate monooxygenase 18 307 5.1E-22 T 26-04-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4V04_RS10820 7102c73d81c312d96ae6b1463b27fec0 575 Pfam PF07282 Putative transposase DNA-binding domain 459 525 2.0E-14 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS10820 7102c73d81c312d96ae6b1463b27fec0 575 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 428 483 8.2E-7 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS03535 364a3e45148dd17c39c3379aea8b25c9 393 Gene3D G3DSA:3.90.350.10 248 280 6.8E-4 T 26-04-2017 IPR014736 Transposase, Tn5-like, core A4V04_RS03535 364a3e45148dd17c39c3379aea8b25c9 393 Pfam PF01609 Transposase DDE domain 2 301 5.1E-15 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS03535 364a3e45148dd17c39c3379aea8b25c9 393 SUPERFAMILY SSF53098 241 312 6.52E-9 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS00845 670ef5b9c4e6413a5a6ee4168660b223 55 Pfam PF00471 Ribosomal protein L33 7 53 2.4E-18 T 26-04-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00845 670ef5b9c4e6413a5a6ee4168660b223 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 2.0E-24 T 26-04-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00845 670ef5b9c4e6413a5a6ee4168660b223 55 SUPERFAMILY SSF57829 1 53 8.55E-20 T 26-04-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 A4V04_RS00845 670ef5b9c4e6413a5a6ee4168660b223 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 14.582 T 26-04-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00845 670ef5b9c4e6413a5a6ee4168660b223 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 26-04-2017 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS03810 0c282caf68af60e8defaf64f7203781e 248 Pfam PF12833 Helix-turn-helix domain 168 245 1.0E-18 T 26-04-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4V04_RS03810 0c282caf68af60e8defaf64f7203781e 248 Gene3D G3DSA:2.60.120.10 18 80 8.8E-9 T 26-04-2017 IPR014710 RmlC-like jelly roll fold A4V04_RS03810 0c282caf68af60e8defaf64f7203781e 248 SUPERFAMILY SSF51182 18 189 4.8E-10 T 26-04-2017 IPR011051 RmlC-like cupin domain A4V04_RS03810 0c282caf68af60e8defaf64f7203781e 248 Gene3D G3DSA:1.10.10.60 199 243 1.6E-6 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS03810 0c282caf68af60e8defaf64f7203781e 248 Gene3D G3DSA:1.10.10.60 146 198 1.0E-7 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS03810 0c282caf68af60e8defaf64f7203781e 248 SMART SM00342 162 244 9.4E-14 T 26-04-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4V04_RS03810 0c282caf68af60e8defaf64f7203781e 248 SUPERFAMILY SSF46689 198 245 8.96E-6 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS03810 0c282caf68af60e8defaf64f7203781e 248 Pfam PF02311 AraC-like ligand binding domain 21 133 6.7E-6 T 26-04-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A4V04_RS05460 9663528fb5c5be939303a826d375d8bc 543 Pfam PF05681 Fumarate hydratase (Fumerase) 51 327 3.2E-86 T 26-04-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A4V04_RS05460 9663528fb5c5be939303a826d375d8bc 543 Pfam PF05683 Fumarase C-terminus 333 538 1.3E-87 T 26-04-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A4V04_RS05460 9663528fb5c5be939303a826d375d8bc 543 SUPERFAMILY SSF117457 362 536 2.35E-59 T 26-04-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A4V04_RS05460 9663528fb5c5be939303a826d375d8bc 543 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 50 326 5.5E-34 T 26-04-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A4V04_RS05460 9663528fb5c5be939303a826d375d8bc 543 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 374 537 1.8E-57 T 26-04-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A4V04_RS05460 9663528fb5c5be939303a826d375d8bc 543 PIRSF PIRSF001394 31 543 1.6E-214 T 26-04-2017 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 A4V04_RS05460 9663528fb5c5be939303a826d375d8bc 543 Gene3D G3DSA:3.20.130.10 350 537 1.1E-70 T 26-04-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A4V04_RS11075 c433e8e61d9af2b3686293bfb3115ab6 267 Gene3D G3DSA:3.10.270.10 8 260 6.6E-98 T 26-04-2017 A4V04_RS11075 c433e8e61d9af2b3686293bfb3115ab6 267 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 148 266 8.3E-32 T 26-04-2017 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442 A4V04_RS11075 c433e8e61d9af2b3686293bfb3115ab6 267 Pfam PF02649 Type I GTP cyclohydrolase folE2 9 257 6.8E-88 T 26-04-2017 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442 A4V04_RS11075 c433e8e61d9af2b3686293bfb3115ab6 267 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 9 262 35.079 T 26-04-2017 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442 A4V04_RS04335 6f26a77eac35fcd79bd27184823ae978 476 Gene3D G3DSA:1.10.8.60 171 238 1.9E-8 T 26-04-2017 A4V04_RS04335 6f26a77eac35fcd79bd27184823ae978 476 Gene3D G3DSA:3.40.50.300 24 170 1.9E-30 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04335 6f26a77eac35fcd79bd27184823ae978 476 SUPERFAMILY SSF52540 25 246 7.3E-45 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04335 6f26a77eac35fcd79bd27184823ae978 476 SMART SM00382 65 182 1.9E-13 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS04335 6f26a77eac35fcd79bd27184823ae978 476 SUPERFAMILY SSF48019 262 443 1.36E-69 T 26-04-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A4V04_RS04335 6f26a77eac35fcd79bd27184823ae978 476 Gene3D G3DSA:1.20.272.10 259 357 7.9E-42 T 26-04-2017 A4V04_RS04335 6f26a77eac35fcd79bd27184823ae978 476 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 69 174 2.5E-13 T 26-04-2017 IPR003959 ATPase, AAA-type, core GO:0005524 A4V04_RS04335 6f26a77eac35fcd79bd27184823ae978 476 Pfam PF12002 MgsA AAA+ ATPase C terminal 278 444 4.0E-63 T 26-04-2017 IPR021886 MgsA AAA+ ATPase C-terminal A4V04_RS04335 6f26a77eac35fcd79bd27184823ae978 476 Pfam PF16193 AAA C-terminal domain 201 277 3.6E-20 T 26-04-2017 IPR032423 AAA ATPase, C-terminal domain A4V04_RS04335 6f26a77eac35fcd79bd27184823ae978 476 Gene3D G3DSA:1.10.3710.10 358 452 3.8E-31 T 26-04-2017 A4V04_RS08685 a3655e13abfcb2544e27befb98f8807b 155 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 113 123 - T 26-04-2017 IPR020549 Endoribonuclease YbeY, conserved site A4V04_RS08685 a3655e13abfcb2544e27befb98f8807b 155 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 10 147 20.707 T 26-04-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A4V04_RS08685 a3655e13abfcb2544e27befb98f8807b 155 Gene3D G3DSA:3.40.390.30 26 152 1.6E-41 T 26-04-2017 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 A4V04_RS08685 a3655e13abfcb2544e27befb98f8807b 155 SUPERFAMILY SSF55486 27 152 2.08E-38 T 26-04-2017 A4V04_RS08685 a3655e13abfcb2544e27befb98f8807b 155 Pfam PF02130 Uncharacterized protein family UPF0054 29 141 2.2E-31 T 26-04-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A4V04_RS08685 a3655e13abfcb2544e27befb98f8807b 155 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 44 143 2.4E-32 T 26-04-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A4V04_RS09835 2f25bce392e072054bebad8063e33c49 218 Gene3D G3DSA:3.40.1050.10 4 208 3.5E-64 T 26-04-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4V04_RS09835 2f25bce392e072054bebad8063e33c49 218 SUPERFAMILY SSF53056 4 209 6.15E-61 T 26-04-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4V04_RS09835 2f25bce392e072054bebad8063e33c49 218 Pfam PF00484 Carbonic anhydrase 37 195 1.4E-45 T 26-04-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4V04_RS09835 2f25bce392e072054bebad8063e33c49 218 SMART SM00947 30 199 8.1E-56 T 26-04-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4V04_RS12385 09553f39cb9e048e66108b982c8b60db 329 Pfam PF02470 MlaD protein 44 138 1.9E-13 T 26-04-2017 IPR003399 Mce/MlaD A4V04_RS09790 5557dea3aca51d0200df2f039bef0732 660 SUPERFAMILY SSF56601 253 610 1.78E-100 T 26-04-2017 IPR012338 Beta-lactamase/transpeptidase-like A4V04_RS09790 5557dea3aca51d0200df2f039bef0732 660 Pfam PF03717 Penicillin-binding Protein dimerisation domain 64 238 7.4E-41 T 26-04-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A4V04_RS09790 5557dea3aca51d0200df2f039bef0732 660 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 19 610 1.5E-223 T 26-04-2017 IPR017790 Penicillin-binding protein 2 GO:0016020 A4V04_RS09790 5557dea3aca51d0200df2f039bef0732 660 Gene3D G3DSA:3.40.710.10 252 610 2.8E-111 T 26-04-2017 IPR012338 Beta-lactamase/transpeptidase-like A4V04_RS09790 5557dea3aca51d0200df2f039bef0732 660 Gene3D G3DSA:3.90.1310.10 130 251 4.4E-36 T 26-04-2017 A4V04_RS09790 5557dea3aca51d0200df2f039bef0732 660 SUPERFAMILY SSF56519 56 252 6.93E-45 T 26-04-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A4V04_RS09790 5557dea3aca51d0200df2f039bef0732 660 Pfam PF00905 Penicillin binding protein transpeptidase domain 270 607 3.6E-77 T 26-04-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4V04_RS03585 1dc1cfb9a6b4288cefa03a1e1e5d5a87 547 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 1 547 42.81 T 26-04-2017 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A4V04_RS03585 1dc1cfb9a6b4288cefa03a1e1e5d5a87 547 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 98 108 - T 26-04-2017 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A4V04_RS03585 1dc1cfb9a6b4288cefa03a1e1e5d5a87 547 Gene3D G3DSA:3.30.1510.10 124 239 2.0E-42 T 26-04-2017 A4V04_RS03585 1dc1cfb9a6b4288cefa03a1e1e5d5a87 547 Gene3D G3DSA:3.40.50.300 240 433 4.3E-130 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03585 1dc1cfb9a6b4288cefa03a1e1e5d5a87 547 Gene3D G3DSA:3.40.50.300 14 123 4.3E-130 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03585 1dc1cfb9a6b4288cefa03a1e1e5d5a87 547 Gene3D G3DSA:3.10.410.10 436 524 3.6E-33 T 26-04-2017 A4V04_RS03585 1dc1cfb9a6b4288cefa03a1e1e5d5a87 547 Pfam PF01268 Formate--tetrahydrofolate ligase 3 546 7.1E-235 T 26-04-2017 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A4V04_RS03585 1dc1cfb9a6b4288cefa03a1e1e5d5a87 547 SUPERFAMILY SSF52540 4 541 1.36E-213 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10105 b4597a5a6d47452b17539972f22b8daf 470 SUPERFAMILY SSF51556 55 209 2.18E-13 T 26-04-2017 IPR032466 Metal-dependent hydrolase A4V04_RS10105 b4597a5a6d47452b17539972f22b8daf 470 SUPERFAMILY SSF51556 325 391 2.18E-13 T 26-04-2017 IPR032466 Metal-dependent hydrolase A4V04_RS10105 b4597a5a6d47452b17539972f22b8daf 470 Pfam PF01979 Amidohydrolase family 52 417 1.4E-15 T 26-04-2017 IPR006680 Amidohydrolase-related GO:0016787 A4V04_RS10105 b4597a5a6d47452b17539972f22b8daf 470 Gene3D G3DSA:2.30.40.10 1 65 6.3E-17 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS10105 b4597a5a6d47452b17539972f22b8daf 470 Gene3D G3DSA:3.20.20.140 343 415 1.9E-18 T 26-04-2017 A4V04_RS10105 b4597a5a6d47452b17539972f22b8daf 470 Gene3D G3DSA:3.20.20.140 66 286 1.9E-18 T 26-04-2017 A4V04_RS10105 b4597a5a6d47452b17539972f22b8daf 470 SUPERFAMILY SSF51338 1 68 8.87E-19 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS09070 b8afba9f588b607939f6ef333147906a 403 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 168 9.3E-24 T 26-04-2017 IPR005225 Small GTP-binding protein domain GO:0005525 A4V04_RS09070 b8afba9f588b607939f6ef333147906a 403 Gene3D G3DSA:3.40.50.300 6 175 4.1E-36 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09070 b8afba9f588b607939f6ef333147906a 403 Pfam PF01926 50S ribosome-binding GTPase 15 129 2.7E-18 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS09070 b8afba9f588b607939f6ef333147906a 403 SUPERFAMILY SSF52540 15 183 2.77E-37 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09070 b8afba9f588b607939f6ef333147906a 403 TIGRFAM TIGR03918 GTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF 6 398 1.9E-167 T 26-04-2017 IPR023873 [FeFe]-hydrogenase H-cluster maturation GTPase HydF A4V04_RS02810 82bda2818094ac4caad5a13b173acb79 217 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 83 179 4.8E-10 T 26-04-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4V04_RS02810 82bda2818094ac4caad5a13b173acb79 217 Gene3D G3DSA:3.40.50.1000 68 215 1.7E-41 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS02810 82bda2818094ac4caad5a13b173acb79 217 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 86 185 2.9E-12 T 26-04-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4V04_RS02810 82bda2818094ac4caad5a13b173acb79 217 SUPERFAMILY SSF56784 3 214 1.42E-56 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS02810 82bda2818094ac4caad5a13b173acb79 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 185 1.8E-36 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS10370 74782cf4227c1de93d99c1630746bac4 471 SUPERFAMILY SSF56425 282 413 7.74E-22 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10370 74782cf4227c1de93d99c1630746bac4 471 Gene3D G3DSA:3.50.50.60 21 256 6.4E-92 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10370 74782cf4227c1de93d99c1630746bac4 471 Gene3D G3DSA:3.50.50.60 409 469 6.4E-92 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10370 74782cf4227c1de93d99c1630746bac4 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 26 45 1.6E-7 T 26-04-2017 A4V04_RS10370 74782cf4227c1de93d99c1630746bac4 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 417 439 1.6E-7 T 26-04-2017 A4V04_RS10370 74782cf4227c1de93d99c1630746bac4 471 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 25 464 4.0E-109 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS10370 74782cf4227c1de93d99c1630746bac4 471 SUPERFAMILY SSF51905 24 265 3.9E-57 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10370 74782cf4227c1de93d99c1630746bac4 471 SUPERFAMILY SSF51905 412 469 3.9E-57 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS10370 74782cf4227c1de93d99c1630746bac4 471 Gene3D G3DSA:3.90.700.10 281 399 3.3E-21 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS10370 74782cf4227c1de93d99c1630746bac4 471 Pfam PF00890 FAD binding domain 25 453 3.0E-74 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS06300 3a274eff7ae4f619c30b249adbfadff8 96 Gene3D G3DSA:2.10.260.10 1 94 5.1E-12 T 26-04-2017 A4V04_RS06300 3a274eff7ae4f619c30b249adbfadff8 96 SUPERFAMILY SSF89447 3 52 2.62E-9 T 26-04-2017 A4V04_RS06300 3a274eff7ae4f619c30b249adbfadff8 96 SMART SM00966 7 52 6.2E-4 T 26-04-2017 IPR007159 SpoVT-AbrB domain GO:0003677 A4V04_RS07875 01b801de9dc26ed5d51f94648e911409 205 Gene3D G3DSA:3.40.50.2300 12 148 9.4E-33 T 26-04-2017 A4V04_RS07875 01b801de9dc26ed5d51f94648e911409 205 SUPERFAMILY SSF52172 12 149 2.13E-33 T 26-04-2017 IPR011006 CheY-like superfamily A4V04_RS07875 01b801de9dc26ed5d51f94648e911409 205 Gene3D G3DSA:1.10.10.10 149 194 5.1E-18 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07875 01b801de9dc26ed5d51f94648e911409 205 SMART SM00448 10 121 5.4E-27 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS07875 01b801de9dc26ed5d51f94648e911409 205 SMART SM00421 145 202 1.0E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS07875 01b801de9dc26ed5d51f94648e911409 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 1.3E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS07875 01b801de9dc26ed5d51f94648e911409 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 1.3E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS07875 01b801de9dc26ed5d51f94648e911409 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 1.3E-11 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS07875 01b801de9dc26ed5d51f94648e911409 205 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 194 4.9E-16 T 26-04-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4V04_RS07875 01b801de9dc26ed5d51f94648e911409 205 SUPERFAMILY SSF46894 139 194 1.05E-14 T 26-04-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4V04_RS07875 01b801de9dc26ed5d51f94648e911409 205 Pfam PF00072 Response regulator receiver domain 12 122 7.7E-26 T 26-04-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4V04_RS05355 18c2e07ccedd9ee1da64c073b28e79a8 288 Pfam PF00581 Rhodanese-like domain 165 278 5.2E-8 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS05355 18c2e07ccedd9ee1da64c073b28e79a8 288 Pfam PF00581 Rhodanese-like domain 23 136 7.5E-15 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS05355 18c2e07ccedd9ee1da64c073b28e79a8 288 Gene3D G3DSA:3.40.250.10 3 155 4.2E-39 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS05355 18c2e07ccedd9ee1da64c073b28e79a8 288 Gene3D G3DSA:3.40.250.10 166 285 1.6E-26 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS05355 18c2e07ccedd9ee1da64c073b28e79a8 288 SUPERFAMILY SSF52821 3 152 1.11E-35 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS05355 18c2e07ccedd9ee1da64c073b28e79a8 288 SMART SM00450 163 283 5.1E-4 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS05355 18c2e07ccedd9ee1da64c073b28e79a8 288 SMART SM00450 7 140 3.2E-16 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS05355 18c2e07ccedd9ee1da64c073b28e79a8 288 SUPERFAMILY SSF52821 166 286 5.63E-24 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS04230 3cb54a40c2b0bb6a94ef41efb6a22cd3 258 Pfam PF03180 NLPA lipoprotein 23 258 8.8E-97 T 26-04-2017 IPR004872 Lipoprotein NlpA family A4V04_RS04230 3cb54a40c2b0bb6a94ef41efb6a22cd3 258 Gene3D G3DSA:3.40.190.10 21 151 1.6E-56 T 26-04-2017 A4V04_RS04230 3cb54a40c2b0bb6a94ef41efb6a22cd3 258 PIRSF PIRSF002854 1 258 1.5E-108 T 26-04-2017 IPR004872 Lipoprotein NlpA family A4V04_RS04230 3cb54a40c2b0bb6a94ef41efb6a22cd3 258 SUPERFAMILY SSF53850 22 258 2.29E-90 T 26-04-2017 A4V04_RS05585 e58c26198ff44b3dc9408afcb6dc4dd8 385 Gene3D G3DSA:1.20.910.10 174 384 3.8E-41 T 26-04-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4V04_RS05585 e58c26198ff44b3dc9408afcb6dc4dd8 385 Pfam PF03070 TENA/THI-4/PQQC family 186 383 1.0E-22 T 26-04-2017 IPR004305 Thiaminase-2/PQQC A4V04_RS05585 e58c26198ff44b3dc9408afcb6dc4dd8 385 SUPERFAMILY SSF48613 174 383 9.79E-34 T 26-04-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4V04_RS08370 6998c085ab2e719f76ecce5d871525e1 326 SUPERFAMILY SSF161098 94 305 3.01E-19 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS08370 6998c085ab2e719f76ecce5d871525e1 326 Gene3D G3DSA:1.10.3720.10 94 315 1.7E-20 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS08370 6998c085ab2e719f76ecce5d871525e1 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 2.0E-41 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS13005 37a8c92628da200861eabc4e31102895 240 Pfam PF01580 FtsK/SpoIIIE family 8 158 1.2E-19 T 26-04-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4V04_RS13005 37a8c92628da200861eabc4e31102895 240 SUPERFAMILY SSF52540 7 236 2.07E-10 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13005 37a8c92628da200861eabc4e31102895 240 Gene3D G3DSA:3.40.50.300 8 230 7.0E-18 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07360 11d980f6f249b2de366890536088168a 180 Pfam PF13247 4Fe-4S dicluster domain 45 138 1.6E-23 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07360 11d980f6f249b2de366890536088168a 180 Gene3D G3DSA:3.30.70.20 124 178 2.7E-11 T 26-04-2017 A4V04_RS07360 11d980f6f249b2de366890536088168a 180 Gene3D G3DSA:3.30.70.20 1 60 2.6E-11 T 26-04-2017 A4V04_RS07360 11d980f6f249b2de366890536088168a 180 Pfam PF12800 4Fe-4S binding domain 12 24 0.0046 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07360 11d980f6f249b2de366890536088168a 180 Gene3D G3DSA:3.30.70.20 61 88 2.3E-13 T 26-04-2017 A4V04_RS07360 11d980f6f249b2de366890536088168a 180 Gene3D G3DSA:3.30.70.20 89 123 1.6E-11 T 26-04-2017 A4V04_RS07360 11d980f6f249b2de366890536088168a 180 SUPERFAMILY SSF54862 1 153 1.36E-52 T 26-04-2017 A4V04_RS07360 11d980f6f249b2de366890536088168a 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 84 95 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS02520 31c38222cb45870866f2bb63fba1e6fe 193 Gene3D G3DSA:3.40.50.360 4 192 3.1E-37 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS02520 31c38222cb45870866f2bb63fba1e6fe 193 SUPERFAMILY SSF52218 4 192 2.39E-36 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS02520 31c38222cb45870866f2bb63fba1e6fe 193 Pfam PF02525 Flavodoxin-like fold 5 188 7.1E-29 T 26-04-2017 IPR003680 Flavodoxin-like fold A4V04_RS05185 49c8b19783302ea5fc93cc135101489f 304 Gene3D G3DSA:3.30.70.1400 18 101 3.6E-26 T 26-04-2017 A4V04_RS05185 49c8b19783302ea5fc93cc135101489f 304 Pfam PF01571 Aminomethyltransferase folate-binding domain 20 102 4.2E-7 T 26-04-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal A4V04_RS05185 49c8b19783302ea5fc93cc135101489f 304 SUPERFAMILY SSF103025 13 228 5.18E-39 T 26-04-2017 A4V04_RS05185 49c8b19783302ea5fc93cc135101489f 304 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 180 236 7.0E-20 T 26-04-2017 IPR017703 YgfZ/GcvT conserved site A4V04_RS08600 e947c294e89aeec3d4e7d5eb379ff4a5 165 Gene3D G3DSA:3.30.1330.60 54 160 2.0E-32 T 26-04-2017 IPR006665 OmpA-like domain A4V04_RS08600 e947c294e89aeec3d4e7d5eb379ff4a5 165 PRINTS PR01021 OMPA domain signature 105 121 2.6E-13 T 26-04-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A4V04_RS08600 e947c294e89aeec3d4e7d5eb379ff4a5 165 PRINTS PR01021 OMPA domain signature 60 82 2.6E-13 T 26-04-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A4V04_RS08600 e947c294e89aeec3d4e7d5eb379ff4a5 165 PRINTS PR01021 OMPA domain signature 90 105 2.6E-13 T 26-04-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A4V04_RS08600 e947c294e89aeec3d4e7d5eb379ff4a5 165 SUPERFAMILY SSF103088 55 159 1.57E-32 T 26-04-2017 IPR006665 OmpA-like domain A4V04_RS08600 e947c294e89aeec3d4e7d5eb379ff4a5 165 Pfam PF00691 OmpA family 59 154 6.8E-20 T 26-04-2017 IPR006665 OmpA-like domain A4V04_RS08600 e947c294e89aeec3d4e7d5eb379ff4a5 165 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 58 160 3.5E-40 T 26-04-2017 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 A4V04_RS03295 0ef50ce68f7759d9e522fdb5a76e6d24 259 SUPERFAMILY SSF75217 9 171 5.76E-28 T 26-04-2017 IPR029028 Alpha/beta knot methyltransferases A4V04_RS03295 0ef50ce68f7759d9e522fdb5a76e6d24 259 Gene3D G3DSA:3.40.1280.10 10 171 3.1E-24 T 26-04-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4V04_RS03295 0ef50ce68f7759d9e522fdb5a76e6d24 259 Pfam PF00588 SpoU rRNA Methylase family 10 164 1.9E-29 T 26-04-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4V04_RS03295 0ef50ce68f7759d9e522fdb5a76e6d24 259 PIRSF PIRSF004808 7 255 2.8E-56 T 26-04-2017 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 A4V04_RS09840 58142f0a42283b9f4a3b5742a2af0056 596 Pfam PF01609 Transposase DDE domain 247 516 4.5E-12 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS09840 58142f0a42283b9f4a3b5742a2af0056 596 SUPERFAMILY SSF53098 220 525 9.86E-7 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS06295 3d60f21846a3a2877de25d9a8bb07e5b 256 SUPERFAMILY SSF54427 113 250 9.2E-36 T 26-04-2017 IPR032710 NTF2-like domain A4V04_RS06295 3d60f21846a3a2877de25d9a8bb07e5b 256 PIRSF PIRSF003299 26 252 7.3E-45 T 26-04-2017 IPR026264 Type IV secretion system protein VirB8/PtlE GO:0030255 A4V04_RS06295 3d60f21846a3a2877de25d9a8bb07e5b 256 Pfam PF04335 VirB8 protein 40 250 2.9E-43 T 26-04-2017 IPR007430 Bacterial virulence protein VirB8 GO:0016020 A4V04_RS11600 a68d1f6daf8c398037323184bc9455a4 745 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 171 609 1.3E-45 T 26-04-2017 IPR000914 Solute-binding protein family 5 domain A4V04_RS11600 a68d1f6daf8c398037323184bc9455a4 745 Gene3D G3DSA:3.10.105.10 419 665 3.4E-49 T 26-04-2017 A4V04_RS11600 a68d1f6daf8c398037323184bc9455a4 745 Gene3D G3DSA:3.90.76.10 50 307 9.9E-19 T 26-04-2017 A4V04_RS11600 a68d1f6daf8c398037323184bc9455a4 745 SUPERFAMILY SSF53850 42 135 4.34E-77 T 26-04-2017 A4V04_RS11600 a68d1f6daf8c398037323184bc9455a4 745 SUPERFAMILY SSF53850 171 683 4.34E-77 T 26-04-2017 A4V04_RS09755 4b7e8622bc72475245ed5eb0cd893149 316 Pfam PF00892 EamA-like transporter family 9 143 5.0E-19 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS09755 4b7e8622bc72475245ed5eb0cd893149 316 Pfam PF00892 EamA-like transporter family 155 287 7.3E-12 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS09755 4b7e8622bc72475245ed5eb0cd893149 316 SUPERFAMILY SSF103481 44 146 2.35E-13 T 26-04-2017 A4V04_RS09755 4b7e8622bc72475245ed5eb0cd893149 316 SUPERFAMILY SSF103481 198 290 2.48E-8 T 26-04-2017 A4V04_RS00730 d258fc51ce8e348512b12364098e31b0 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 324 1.9E-71 T 26-04-2017 IPR005064 Bordetella uptake gene GO:0030288 A4V04_RS00730 d258fc51ce8e348512b12364098e31b0 329 PIRSF PIRSF017082 1 328 5.9E-70 T 26-04-2017 IPR005064 Bordetella uptake gene GO:0030288 A4V04_RS00730 d258fc51ce8e348512b12364098e31b0 329 SUPERFAMILY SSF53850 114 293 3.8E-12 T 26-04-2017 A4V04_RS08295 6d6ad2fe7c0adf66d3921efe739247ac 268 SUPERFAMILY SSF52266 129 235 2.17E-9 T 26-04-2017 IPR013830 SGNH hydrolase-type esterase domain A4V04_RS08295 6d6ad2fe7c0adf66d3921efe739247ac 268 Gene3D G3DSA:3.40.50.1110 129 232 1.2E-6 T 26-04-2017 IPR013830 SGNH hydrolase-type esterase domain A4V04_RS12580 5b260ea502f87d7691cefa60db44bee3 107 SUPERFAMILY SSF101386 6 94 1.44E-25 T 26-04-2017 A4V04_RS12580 5b260ea502f87d7691cefa60db44bee3 107 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 9 93 1.9E-17 T 26-04-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 A4V04_RS12580 5b260ea502f87d7691cefa60db44bee3 107 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 4 90 20.972 T 26-04-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A4V04_RS12580 5b260ea502f87d7691cefa60db44bee3 107 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 8 90 1.1E-31 T 26-04-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A4V04_RS08750 d74244ddde983dd8900a998ee0fa5abf 314 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 54 77 - T 26-04-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4V04_RS08750 d74244ddde983dd8900a998ee0fa5abf 314 SUPERFAMILY SSF53613 15 310 2.08E-54 T 26-04-2017 IPR029056 Ribokinase-like A4V04_RS08750 d74244ddde983dd8900a998ee0fa5abf 314 Pfam PF00294 pfkB family carbohydrate kinase 14 304 1.3E-41 T 26-04-2017 IPR011611 Carbohydrate kinase PfkB A4V04_RS08750 d74244ddde983dd8900a998ee0fa5abf 314 Gene3D G3DSA:3.40.1190.20 15 310 1.9E-64 T 26-04-2017 IPR029056 Ribokinase-like A4V04_RS08750 d74244ddde983dd8900a998ee0fa5abf 314 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 10 311 5.9E-116 T 26-04-2017 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 A4V04_RS12820 2af534fcbe372694e40681078a17a111 252 Gene3D G3DSA:1.10.10.10 145 215 2.3E-5 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS12820 2af534fcbe372694e40681078a17a111 252 SUPERFAMILY SSF51206 17 131 8.12E-10 T 26-04-2017 IPR018490 Cyclic nucleotide-binding-like A4V04_RS12820 2af534fcbe372694e40681078a17a111 252 Gene3D G3DSA:2.60.120.10 18 124 1.4E-5 T 26-04-2017 IPR014710 RmlC-like jelly roll fold A4V04_RS12275 808cd17c93ff48618e2cadb6e5a340cb 161 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 151 23.916 T 26-04-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS12275 808cd17c93ff48618e2cadb6e5a340cb 161 SUPERFAMILY SSF52121 6 148 3.79E-46 T 26-04-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS12275 808cd17c93ff48618e2cadb6e5a340cb 161 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 144 1.1E-36 T 26-04-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS12275 808cd17c93ff48618e2cadb6e5a340cb 161 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 15 148 4.8E-45 T 26-04-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS12275 808cd17c93ff48618e2cadb6e5a340cb 161 Gene3D G3DSA:3.40.50.960 5 148 5.8E-51 T 26-04-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS00820 c8b24890057dc15145e2c17464c478a9 164 Pfam PF01252 Signal peptidase (SPase) II 21 160 8.3E-37 T 26-04-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A4V04_RS00820 c8b24890057dc15145e2c17464c478a9 164 TIGRFAM TIGR00077 lspA: signal peptidase II 14 162 2.6E-37 T 26-04-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A4V04_RS00820 c8b24890057dc15145e2c17464c478a9 164 ProSitePatterns PS00855 Signal peptidases II signature. 108 120 - T 26-04-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A4V04_RS00820 c8b24890057dc15145e2c17464c478a9 164 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 12 163 15.931 T 26-04-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A4V04_RS00820 c8b24890057dc15145e2c17464c478a9 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 141 157 1.4E-16 T 26-04-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A4V04_RS00820 c8b24890057dc15145e2c17464c478a9 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 105 120 1.4E-16 T 26-04-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A4V04_RS00820 c8b24890057dc15145e2c17464c478a9 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 58 66 1.4E-16 T 26-04-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A4V04_RS00920 80a452875a04624169aae2973071fb49 538 TIGRFAM TIGR00552 nadE: NAD+ synthetase 271 514 6.3E-62 T 26-04-2017 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 A4V04_RS00920 80a452875a04624169aae2973071fb49 538 Gene3D G3DSA:3.60.110.10 2 237 3.1E-50 T 26-04-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4V04_RS00920 80a452875a04624169aae2973071fb49 538 Pfam PF02540 NAD synthase 265 512 1.5E-75 T 26-04-2017 IPR022310 NAD/GMP synthase A4V04_RS00920 80a452875a04624169aae2973071fb49 538 Gene3D G3DSA:3.40.50.620 254 519 2.5E-74 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS00920 80a452875a04624169aae2973071fb49 538 SUPERFAMILY SSF56317 5 229 2.88E-48 T 26-04-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4V04_RS00920 80a452875a04624169aae2973071fb49 538 Pfam PF00795 Carbon-nitrogen hydrolase 5 192 1.4E-21 T 26-04-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4V04_RS00920 80a452875a04624169aae2973071fb49 538 SUPERFAMILY SSF52402 252 520 2.79E-72 T 26-04-2017 A4V04_RS03935 527b33a992774d650e8a709e6b251fae 434 Gene3D G3DSA:1.20.1250.20 5 189 9.4E-9 T 26-04-2017 A4V04_RS03935 527b33a992774d650e8a709e6b251fae 434 Pfam PF07690 Major Facilitator Superfamily 9 355 7.8E-12 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS03935 527b33a992774d650e8a709e6b251fae 434 SUPERFAMILY SSF103473 5 418 6.8E-21 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS11675 cb536a874536afa14886dfc4b1a62f02 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 26-04-2017 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11675 cb536a874536afa14886dfc4b1a62f02 103 SUPERFAMILY SSF141091 1 102 1.07E-35 T 26-04-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11675 cb536a874536afa14886dfc4b1a62f02 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 102 4.4E-35 T 26-04-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11675 cb536a874536afa14886dfc4b1a62f02 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 25.637 T 26-04-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS11675 cb536a874536afa14886dfc4b1a62f02 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.2E-38 T 26-04-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS02750 55a2f3d69d6fca9df8cebe292b14c939 269 SUPERFAMILY SSF56281 10 103 3.93E-22 T 26-04-2017 IPR001279 Metallo-beta-lactamase A4V04_RS02750 55a2f3d69d6fca9df8cebe292b14c939 269 SUPERFAMILY SSF56281 133 255 3.93E-22 T 26-04-2017 IPR001279 Metallo-beta-lactamase A4V04_RS02750 55a2f3d69d6fca9df8cebe292b14c939 269 Gene3D G3DSA:3.60.15.10 14 257 2.9E-23 T 26-04-2017 IPR001279 Metallo-beta-lactamase A4V04_RS02750 55a2f3d69d6fca9df8cebe292b14c939 269 Pfam PF12706 Beta-lactamase superfamily domain 47 118 1.3E-8 T 26-04-2017 IPR001279 Metallo-beta-lactamase A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 SUPERFAMILY SSF56655 46 301 4.45E-83 T 26-04-2017 A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 Gene3D G3DSA:3.30.540.10 47 199 4.8E-51 T 26-04-2017 A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 Pfam PF00459 Inositol monophosphatase family 46 301 2.2E-66 T 26-04-2017 IPR000760 Inositol monophosphatase GO:0046854 A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 PRINTS PR01959 SuhB family inositol monophosphatase signature 147 166 2.0E-22 T 26-04-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 PRINTS PR01959 SuhB family inositol monophosphatase signature 241 253 2.0E-22 T 26-04-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 PRINTS PR01959 SuhB family inositol monophosphatase signature 199 225 2.0E-22 T 26-04-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 PRINTS PR01959 SuhB family inositol monophosphatase signature 60 82 2.0E-22 T 26-04-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 124 137 - T 26-04-2017 IPR020583 Inositol monophosphatase, metal-binding site A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 254 268 - T 26-04-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 Gene3D G3DSA:3.40.190.80 200 300 6.8E-38 T 26-04-2017 A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 PRINTS PR00377 Inositol monophosphatase superfamily signature 103 119 2.7E-55 T 26-04-2017 IPR000760 Inositol monophosphatase GO:0046854 A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 PRINTS PR00377 Inositol monophosphatase superfamily signature 124 140 2.7E-55 T 26-04-2017 IPR000760 Inositol monophosphatase GO:0046854 A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 PRINTS PR00377 Inositol monophosphatase superfamily signature 173 196 2.7E-55 T 26-04-2017 IPR000760 Inositol monophosphatase GO:0046854 A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 PRINTS PR00377 Inositol monophosphatase superfamily signature 220 241 2.7E-55 T 26-04-2017 IPR000760 Inositol monophosphatase GO:0046854 A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 PRINTS PR00377 Inositol monophosphatase superfamily signature 251 275 2.7E-55 T 26-04-2017 IPR000760 Inositol monophosphatase GO:0046854 A4V04_RS03290 91a97f527b1037cba8131fd4d6a11801 306 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 101 2.7E-55 T 26-04-2017 IPR000760 Inositol monophosphatase GO:0046854 A4V04_RS00025 9f3e02ff358fc09f541e075c277e2996 35 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 2 30 3.6E-7 T 26-04-2017 IPR009241 Toxin HigB-like A4V04_RS08530 c49cbbe638d95160a96ac0f882f09cc1 298 PRINTS PR01438 Universal stress protein signature 149 167 2.1E-11 T 26-04-2017 IPR006015 Universal stress protein A A4V04_RS08530 c49cbbe638d95160a96ac0f882f09cc1 298 PRINTS PR01438 Universal stress protein signature 257 269 2.1E-11 T 26-04-2017 IPR006015 Universal stress protein A A4V04_RS08530 c49cbbe638d95160a96ac0f882f09cc1 298 PRINTS PR01438 Universal stress protein signature 275 297 2.1E-11 T 26-04-2017 IPR006015 Universal stress protein A A4V04_RS08530 c49cbbe638d95160a96ac0f882f09cc1 298 SUPERFAMILY SSF52402 151 297 4.27E-26 T 26-04-2017 A4V04_RS08530 c49cbbe638d95160a96ac0f882f09cc1 298 SUPERFAMILY SSF52402 1 143 5.27E-30 T 26-04-2017 A4V04_RS08530 c49cbbe638d95160a96ac0f882f09cc1 298 Pfam PF00582 Universal stress protein family 151 296 8.6E-20 T 26-04-2017 IPR006016 UspA GO:0006950 A4V04_RS08530 c49cbbe638d95160a96ac0f882f09cc1 298 Pfam PF00582 Universal stress protein family 2 140 1.8E-24 T 26-04-2017 IPR006016 UspA GO:0006950 A4V04_RS08530 c49cbbe638d95160a96ac0f882f09cc1 298 Gene3D G3DSA:3.40.50.620 151 296 1.4E-27 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS08530 c49cbbe638d95160a96ac0f882f09cc1 298 Gene3D G3DSA:3.40.50.620 2 142 1.3E-31 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS12020 e4372b5d2754e44f6850e87cddba1cbd 378 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 327 351 - T 26-04-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 A4V04_RS12020 e4372b5d2754e44f6850e87cddba1cbd 378 Pfam PF01098 Cell cycle protein 11 370 1.0E-96 T 26-04-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 A4V04_RS12020 e4372b5d2754e44f6850e87cddba1cbd 378 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 5 377 36.553 T 26-04-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 A4V04_RS12020 e4372b5d2754e44f6850e87cddba1cbd 378 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 8 368 3.1E-115 T 26-04-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 Gene3D G3DSA:3.30.565.10 7 241 3.2E-77 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 SUPERFAMILY SSF54211 235 488 3.72E-93 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 151 1.3E-12 T 26-04-2017 A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 SUPERFAMILY SSF110942 514 625 1.24E-32 T 26-04-2017 A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 Hamap MF_00505 Chaperone protein HtpG [htpG]. 4 625 30.985 T 26-04-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 27 36 - T 26-04-2017 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 Pfam PF00183 Hsp90 protein 221 629 5.9E-126 T 26-04-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 SMART SM00387 29 186 6.5E-7 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 SUPERFAMILY SSF55874 7 217 7.6E-62 T 26-04-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 PRINTS PR00775 90kDa heat shock protein signature 174 191 5.9E-58 T 26-04-2017 IPR020575 Heat shock protein Hsp90, N-terminal A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 PRINTS PR00775 90kDa heat shock protein signature 77 94 5.9E-58 T 26-04-2017 IPR020575 Heat shock protein Hsp90, N-terminal A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 PRINTS PR00775 90kDa heat shock protein signature 192 210 5.9E-58 T 26-04-2017 IPR020575 Heat shock protein Hsp90, N-terminal A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 PRINTS PR00775 90kDa heat shock protein signature 7 27 5.9E-58 T 26-04-2017 IPR020575 Heat shock protein Hsp90, N-terminal A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 PRINTS PR00775 90kDa heat shock protein signature 28 50 5.9E-58 T 26-04-2017 IPR020575 Heat shock protein Hsp90, N-terminal A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 PRINTS PR00775 90kDa heat shock protein signature 95 112 5.9E-58 T 26-04-2017 IPR020575 Heat shock protein Hsp90, N-terminal A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 PRINTS PR00775 90kDa heat shock protein signature 122 144 5.9E-58 T 26-04-2017 IPR020575 Heat shock protein Hsp90, N-terminal A4V04_RS03135 8580bc3ff53ecdc5c89b9a5267e51355 633 PIRSF PIRSF002583 1 633 3.6E-210 T 26-04-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A4V04_RS12045 69e8963a4f64c60a542af3a0f3ec7285 643 Pfam PF00905 Penicillin binding protein transpeptidase domain 268 562 4.5E-76 T 26-04-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4V04_RS12045 69e8963a4f64c60a542af3a0f3ec7285 643 SUPERFAMILY SSF56601 196 577 2.44E-90 T 26-04-2017 IPR012338 Beta-lactamase/transpeptidase-like A4V04_RS12045 69e8963a4f64c60a542af3a0f3ec7285 643 Gene3D G3DSA:3.40.710.10 250 570 5.8E-89 T 26-04-2017 IPR012338 Beta-lactamase/transpeptidase-like A4V04_RS12045 69e8963a4f64c60a542af3a0f3ec7285 643 Pfam PF03717 Penicillin-binding Protein dimerisation domain 83 227 1.2E-15 T 26-04-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A4V04_RS12045 69e8963a4f64c60a542af3a0f3ec7285 643 Gene3D G3DSA:3.90.1310.10 151 249 7.7E-27 T 26-04-2017 A4V04_RS12045 69e8963a4f64c60a542af3a0f3ec7285 643 SUPERFAMILY SSF56519 78 242 1.28E-40 T 26-04-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A4V04_RS04385 0b93be35be1c7247fe716a4252edaecf 236 Pfam PF07670 Nucleoside recognition 94 188 1.8E-6 T 26-04-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A4V04_RS03395 18716af4b71311cbd1596d0867119abb 266 Gene3D G3DSA:3.40.50.720 2 137 8.9E-26 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03395 18716af4b71311cbd1596d0867119abb 266 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 8 120 3.0E-15 T 26-04-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A4V04_RS03395 18716af4b71311cbd1596d0867119abb 266 Gene3D G3DSA:3.30.360.10 138 234 4.6E-26 T 26-04-2017 A4V04_RS03395 18716af4b71311cbd1596d0867119abb 266 PIRSF PIRSF005227 1 265 5.6E-62 T 26-04-2017 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 A4V04_RS03395 18716af4b71311cbd1596d0867119abb 266 SUPERFAMILY SSF51735 1 151 7.66E-18 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03395 18716af4b71311cbd1596d0867119abb 266 Pfam PF01958 Domain of unknown function DUF108 168 253 6.6E-24 T 26-04-2017 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 A4V04_RS03395 18716af4b71311cbd1596d0867119abb 266 SUPERFAMILY SSF55347 124 226 2.62E-18 T 26-04-2017 A4V04_RS00840 48adad1a20d5e29b7f1d59fa71265d50 518 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 359 371 1.5E-27 T 26-04-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS00840 48adad1a20d5e29b7f1d59fa71265d50 518 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 290 300 1.5E-27 T 26-04-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS00840 48adad1a20d5e29b7f1d59fa71265d50 518 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 261 275 1.5E-27 T 26-04-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS00840 48adad1a20d5e29b7f1d59fa71265d50 518 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 409 425 1.5E-27 T 26-04-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS00840 48adad1a20d5e29b7f1d59fa71265d50 518 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 468 485 1.5E-27 T 26-04-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS00840 48adad1a20d5e29b7f1d59fa71265d50 518 Gene3D G3DSA:3.30.70.1170 212 269 3.9E-13 T 26-04-2017 A4V04_RS00840 48adad1a20d5e29b7f1d59fa71265d50 518 Pfam PF01189 16S rRNA methyltransferase RsmB/F 280 483 1.9E-49 T 26-04-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS00840 48adad1a20d5e29b7f1d59fa71265d50 518 SUPERFAMILY SSF53335 199 486 7.98E-68 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS00840 48adad1a20d5e29b7f1d59fa71265d50 518 Gene3D G3DSA:3.40.50.150 271 486 6.9E-58 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS05955 c7d056927580efb288c8ce156f104c54 395 Gene3D G3DSA:3.90.1150.10 287 393 2.7E-21 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS05955 c7d056927580efb288c8ce156f104c54 395 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 1 393 2.2E-174 T 26-04-2017 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 A4V04_RS05955 c7d056927580efb288c8ce156f104c54 395 Pfam PF00155 Aminotransferase class I and II 30 390 4.1E-48 T 26-04-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4V04_RS05955 c7d056927580efb288c8ce156f104c54 395 SUPERFAMILY SSF53383 4 393 3.13E-88 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS05955 c7d056927580efb288c8ce156f104c54 395 Gene3D G3DSA:3.40.640.10 44 286 8.4E-63 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS08735 092b72e844761a1f15fff8bd556de286 315 Gene3D G3DSA:3.40.50.2000 2 157 1.3E-32 T 26-04-2017 A4V04_RS08735 092b72e844761a1f15fff8bd556de286 315 Gene3D G3DSA:3.40.50.2000 172 314 9.8E-26 T 26-04-2017 A4V04_RS08735 092b72e844761a1f15fff8bd556de286 315 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 2 314 1.8E-98 T 26-04-2017 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 A4V04_RS08735 092b72e844761a1f15fff8bd556de286 315 SUPERFAMILY SSF53756 2 314 4.08E-63 T 26-04-2017 A4V04_RS08735 092b72e844761a1f15fff8bd556de286 315 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 76 304 6.1E-48 T 26-04-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 A4V04_RS12255 7b01016784665daae6ebf13b0dfeb112 162 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 13 157 1.2E-50 T 26-04-2017 IPR008136 CinA, C-terminal A4V04_RS12255 7b01016784665daae6ebf13b0dfeb112 162 SUPERFAMILY SSF142433 8 161 5.1E-56 T 26-04-2017 IPR008136 CinA, C-terminal A4V04_RS12255 7b01016784665daae6ebf13b0dfeb112 162 Pfam PF02464 Competence-damaged protein 11 159 1.1E-58 T 26-04-2017 IPR008136 CinA, C-terminal A4V04_RS12255 7b01016784665daae6ebf13b0dfeb112 162 Gene3D G3DSA:3.90.950.20 4 161 1.8E-59 T 26-04-2017 IPR008136 CinA, C-terminal A4V04_RS07525 f7649388372ce20ff76ae50d53ec9901 214 Pfam PF02613 Nitrate reductase delta subunit 48 180 8.6E-30 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS07525 f7649388372ce20ff76ae50d53ec9901 214 SUPERFAMILY SSF89155 67 209 3.01E-42 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS07525 f7649388372ce20ff76ae50d53ec9901 214 SUPERFAMILY SSF89155 10 37 3.01E-42 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS07525 f7649388372ce20ff76ae50d53ec9901 214 Gene3D G3DSA:1.10.3480.10 9 210 7.9E-47 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS08300 36b2ab084b6b01776c44f9a2818e07f4 409 Pfam PF13365 Trypsin-like peptidase domain 240 367 3.8E-24 T 26-04-2017 A4V04_RS08300 36b2ab084b6b01776c44f9a2818e07f4 409 SUPERFAMILY SSF50494 225 393 7.62E-39 T 26-04-2017 IPR009003 Peptidase S1, PA clan A4V04_RS08300 36b2ab084b6b01776c44f9a2818e07f4 409 Gene3D G3DSA:2.40.10.10 210 295 2.2E-17 T 26-04-2017 A4V04_RS08300 36b2ab084b6b01776c44f9a2818e07f4 409 Gene3D G3DSA:2.40.10.10 304 395 1.0E-21 T 26-04-2017 A4V04_RS08300 36b2ab084b6b01776c44f9a2818e07f4 409 PRINTS PR00834 HtrA/DegQ protease family signature 360 377 2.6E-17 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS08300 36b2ab084b6b01776c44f9a2818e07f4 409 PRINTS PR00834 HtrA/DegQ protease family signature 269 289 2.6E-17 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS08300 36b2ab084b6b01776c44f9a2818e07f4 409 PRINTS PR00834 HtrA/DegQ protease family signature 248 260 2.6E-17 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS08300 36b2ab084b6b01776c44f9a2818e07f4 409 PRINTS PR00834 HtrA/DegQ protease family signature 307 331 2.6E-17 T 26-04-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4V04_RS07485 308b4795feb7166b47aba87ad5e6b3d0 168 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 135 4.0E-32 T 26-04-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4V04_RS07485 308b4795feb7166b47aba87ad5e6b3d0 168 SUPERFAMILY SSF55083 1 150 2.75E-40 T 26-04-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4V04_RS07485 308b4795feb7166b47aba87ad5e6b3d0 168 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 135 1.2E-32 T 26-04-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4V04_RS07485 308b4795feb7166b47aba87ad5e6b3d0 168 Gene3D G3DSA:3.30.70.560 3 156 5.6E-47 T 26-04-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4V04_RS06630 7310147556fd65ef0111e72957429b59 431 Pfam PF03313 Serine dehydratase alpha chain 89 425 7.2E-57 T 26-04-2017 IPR005130 Serine dehydratase-like, alpha subunit A4V04_RS06630 7310147556fd65ef0111e72957429b59 431 Hamap MF_01845 UPF0597 protein YhaM [yhaM]. 6 430 35.106 T 26-04-2017 IPR021144 Uncharacterised protein family UPF0597 A4V04_RS06630 7310147556fd65ef0111e72957429b59 431 PIRSF PIRSF006054 2 431 7.4E-160 T 26-04-2017 IPR021144 Uncharacterised protein family UPF0597 A4V04_RS07600 e48856cbc6b41d88987aa9513a1eb32e 218 Pfam PF09335 SNARE associated Golgi protein 49 173 2.5E-19 T 26-04-2017 IPR032816 SNARE associated Golgi protein A4V04_RS09075 17930e5eb1943bd66d57650f322a0b7f 229 Pfam PF01292 Prokaryotic cytochrome b561 14 191 1.4E-12 T 26-04-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 A4V04_RS09075 17930e5eb1943bd66d57650f322a0b7f 229 SUPERFAMILY SSF81342 7 221 1.96E-22 T 26-04-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A4V04_RS09075 17930e5eb1943bd66d57650f322a0b7f 229 Gene3D G3DSA:1.20.950.20 6 222 2.4E-38 T 26-04-2017 A4V04_RS07800 46090af3d64535ecc2218f643c227c88 422 Pfam PF01546 Peptidase family M20/M25/M40 103 418 1.3E-21 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS07800 46090af3d64535ecc2218f643c227c88 422 Pfam PF07687 Peptidase dimerisation domain 222 310 1.0E-9 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS07800 46090af3d64535ecc2218f643c227c88 422 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 9 409 5.0E-81 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS07800 46090af3d64535ecc2218f643c227c88 422 SUPERFAMILY SSF55031 220 326 7.98E-23 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS07800 46090af3d64535ecc2218f643c227c88 422 PIRSF PIRSF005962 1 422 1.7E-102 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS07800 46090af3d64535ecc2218f643c227c88 422 SUPERFAMILY SSF53187 85 233 2.55E-57 T 26-04-2017 A4V04_RS07800 46090af3d64535ecc2218f643c227c88 422 SUPERFAMILY SSF53187 3 47 2.55E-57 T 26-04-2017 A4V04_RS07800 46090af3d64535ecc2218f643c227c88 422 SUPERFAMILY SSF53187 332 420 2.55E-57 T 26-04-2017 A4V04_RS07800 46090af3d64535ecc2218f643c227c88 422 Gene3D G3DSA:3.40.630.10 85 215 6.2E-67 T 26-04-2017 A4V04_RS07800 46090af3d64535ecc2218f643c227c88 422 Gene3D G3DSA:3.40.630.10 329 420 6.2E-67 T 26-04-2017 A4V04_RS07800 46090af3d64535ecc2218f643c227c88 422 Gene3D G3DSA:3.40.630.10 3 47 6.2E-67 T 26-04-2017 A4V04_RS07800 46090af3d64535ecc2218f643c227c88 422 Gene3D G3DSA:3.30.70.360 220 324 4.0E-26 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS01000 67f4499806e40d195af5ac553b7a6776 454 SUPERFAMILY SSF48557 10 452 3.46E-100 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS01000 67f4499806e40d195af5ac553b7a6776 454 ProSitePatterns PS00163 Fumarate lyases signature. 293 302 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS01000 67f4499806e40d195af5ac553b7a6776 454 PRINTS PR00149 Fumarate lyase superfamily signature 161 179 3.8E-18 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01000 67f4499806e40d195af5ac553b7a6776 454 PRINTS PR00149 Fumarate lyase superfamily signature 293 309 3.8E-18 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01000 67f4499806e40d195af5ac553b7a6776 454 PRINTS PR00149 Fumarate lyase superfamily signature 116 134 3.8E-18 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01000 67f4499806e40d195af5ac553b7a6776 454 PRINTS PR00149 Fumarate lyase superfamily signature 250 277 3.8E-18 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01000 67f4499806e40d195af5ac553b7a6776 454 Pfam PF00206 Lyase 14 311 1.4E-53 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS01000 67f4499806e40d195af5ac553b7a6776 454 Gene3D G3DSA:1.10.275.10 1 118 7.8E-46 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS01000 67f4499806e40d195af5ac553b7a6776 454 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 450 2.7E-122 T 26-04-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4V04_RS01000 67f4499806e40d195af5ac553b7a6776 454 Gene3D G3DSA:1.20.200.10 119 388 1.8E-83 T 26-04-2017 A4V04_RS01000 67f4499806e40d195af5ac553b7a6776 454 Gene3D G3DSA:1.10.40.30 389 444 1.8E-32 T 26-04-2017 A4V04_RS01000 67f4499806e40d195af5ac553b7a6776 454 Pfam PF08328 Adenylosuccinate lyase C-terminal 330 444 6.3E-51 T 26-04-2017 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 A4V04_RS07220 62b3cc164603bb47090ade2d3d0cec3c 458 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 160 168 - T 26-04-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A4V04_RS07220 62b3cc164603bb47090ade2d3d0cec3c 458 Pfam PF00271 Helicase conserved C-terminal domain 240 352 1.3E-26 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS07220 62b3cc164603bb47090ade2d3d0cec3c 458 SMART SM00490 271 352 2.3E-30 T 26-04-2017 IPR001650 Helicase, C-terminal A4V04_RS07220 62b3cc164603bb47090ade2d3d0cec3c 458 Gene3D G3DSA:3.40.50.300 219 388 5.1E-53 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07220 62b3cc164603bb47090ade2d3d0cec3c 458 SMART SM00487 24 229 2.8E-63 T 26-04-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4V04_RS07220 62b3cc164603bb47090ade2d3d0cec3c 458 Gene3D G3DSA:3.40.50.300 3 218 9.9E-86 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07220 62b3cc164603bb47090ade2d3d0cec3c 458 SUPERFAMILY SSF52540 81 373 3.07E-75 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07220 62b3cc164603bb47090ade2d3d0cec3c 458 Pfam PF00270 DEAD/DEAH box helicase 29 203 6.9E-51 T 26-04-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4V04_RS11470 a740c131e05ebe39610db4ed0f43f57f 494 SUPERFAMILY SSF103365 93 470 1.44E-104 T 26-04-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A4V04_RS11470 a740c131e05ebe39610db4ed0f43f57f 494 Pfam PF01139 tRNA-splicing ligase RtcB 210 468 6.3E-69 T 26-04-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A4V04_RS11470 a740c131e05ebe39610db4ed0f43f57f 494 Pfam PF01139 tRNA-splicing ligase RtcB 105 187 1.4E-15 T 26-04-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A4V04_RS09355 0d8cae1e8b5c5c3a59c7f2db8b04c96d 415 Gene3D G3DSA:1.20.1250.20 232 409 1.4E-19 T 26-04-2017 A4V04_RS09355 0d8cae1e8b5c5c3a59c7f2db8b04c96d 415 Gene3D G3DSA:1.20.1250.20 10 193 9.8E-20 T 26-04-2017 A4V04_RS09355 0d8cae1e8b5c5c3a59c7f2db8b04c96d 415 Pfam PF07690 Major Facilitator Superfamily 234 408 5.2E-16 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS09355 0d8cae1e8b5c5c3a59c7f2db8b04c96d 415 SUPERFAMILY SSF103473 6 409 1.01E-50 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS03660 f56d627ccfe732f662377d0378d49cd1 300 SUPERFAMILY SSF48179 171 294 3.97E-36 T 26-04-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4V04_RS03660 f56d627ccfe732f662377d0378d49cd1 300 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 173 293 2.4E-30 T 26-04-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A4V04_RS03660 f56d627ccfe732f662377d0378d49cd1 300 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 13 26 - T 26-04-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4V04_RS03660 f56d627ccfe732f662377d0378d49cd1 300 Gene3D G3DSA:3.40.50.720 8 170 2.4E-49 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03660 f56d627ccfe732f662377d0378d49cd1 300 SUPERFAMILY SSF51735 9 171 4.1E-48 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS03660 f56d627ccfe732f662377d0378d49cd1 300 PIRSF PIRSF000103 3 300 1.7E-67 T 26-04-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4V04_RS03660 f56d627ccfe732f662377d0378d49cd1 300 Gene3D G3DSA:1.10.1040.10 173 295 4.2E-38 T 26-04-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4V04_RS03660 f56d627ccfe732f662377d0378d49cd1 300 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 167 1.4E-44 T 26-04-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A4V04_RS10745 d22c69c5971cc3bd3fcd0769e4bc9137 135 Pfam PF06155 Protein of unknown function (DUF971) 7 89 2.7E-25 T 26-04-2017 IPR010376 Domain of unknown function DUF971 Reactome: R-HSA-71262 A4V04_RS11025 42345f576b6937f5a8cda1503ece40dc 211 SUPERFAMILY SSF89155 5 163 1.19E-23 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS11025 42345f576b6937f5a8cda1503ece40dc 211 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 10 159 2.7E-28 T 26-04-2017 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 A4V04_RS11025 42345f576b6937f5a8cda1503ece40dc 211 Gene3D G3DSA:1.10.3480.10 10 128 3.2E-5 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS11025 42345f576b6937f5a8cda1503ece40dc 211 Pfam PF02613 Nitrate reductase delta subunit 35 157 1.6E-11 T 26-04-2017 IPR020945 DMSO/Nitrate reductase chaperone A4V04_RS05140 56112b0a19260140b90d5036f628b58c 135 Pfam PF14229 Domain of unknown function (DUF4332) 9 129 1.7E-37 T 26-04-2017 IPR025567 Domain of unknown function DUF4332 KEGG: 00970+6.1.1.6 A4V04_RS05140 56112b0a19260140b90d5036f628b58c 135 Gene3D G3DSA:1.10.150.20 5 27 6.9E-4 T 26-04-2017 A4V04_RS05140 56112b0a19260140b90d5036f628b58c 135 Gene3D G3DSA:1.10.150.20 52 102 9.2E-6 T 26-04-2017 A4V04_RS02185 a3b452d035b65825d23033008af3f48e 61 Pfam PF07751 Abi-like protein 9 52 7.1E-8 T 26-04-2017 IPR011664 Abortive infection system protein AbiD/AbiF-like A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 SUPERFAMILY SSF51735 122 279 4.06E-51 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 3.5E-83 T 26-04-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 3.5E-83 T 26-04-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 3.5E-83 T 26-04-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 3.5E-83 T 26-04-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 3.5E-83 T 26-04-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 3.5E-83 T 26-04-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 3.5E-83 T 26-04-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 SUPERFAMILY SSF53223 1 121 1.73E-41 T 26-04-2017 A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 Gene3D G3DSA:3.40.192.10 7 139 9.4E-51 T 26-04-2017 A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 26-04-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 280 2.7E-69 T 26-04-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 38.889 T 26-04-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 1.1E-42 T 26-04-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 Gene3D G3DSA:3.40.50.720 140 263 4.7E-55 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS05635 36555f8d04a0ef4ca66f19ab3080037b 288 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 26-04-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4V04_RS08355 84c72d9d236b08d42c309cd6c1c93d62 346 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS08355 84c72d9d236b08d42c309cd6c1c93d62 346 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 320 4.8E-26 T 26-04-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4V04_RS08355 84c72d9d236b08d42c309cd6c1c93d62 346 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 301 7.7E-19 T 26-04-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4V04_RS08355 84c72d9d236b08d42c309cd6c1c93d62 346 SUPERFAMILY SSF52540 7 256 3.9E-65 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08355 84c72d9d236b08d42c309cd6c1c93d62 346 SMART SM00382 36 235 8.7E-15 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS08355 84c72d9d236b08d42c309cd6c1c93d62 346 Gene3D G3DSA:3.40.50.300 6 259 5.4E-75 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08355 84c72d9d236b08d42c309cd6c1c93d62 346 Pfam PF00005 ABC transporter 27 185 7.3E-31 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS05890 be485d5d87775c2036eea0567d839ff5 186 Hamap MF_00040 Ribosome-recycling factor [frr]. 4 186 27.094 T 26-04-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A4V04_RS05890 be485d5d87775c2036eea0567d839ff5 186 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 186 3.8E-69 T 26-04-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A4V04_RS05890 be485d5d87775c2036eea0567d839ff5 186 SUPERFAMILY SSF55194 5 185 2.35E-69 T 26-04-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A4V04_RS05890 be485d5d87775c2036eea0567d839ff5 186 Gene3D G3DSA:1.10.132.20 67 186 1.0E-45 T 26-04-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A4V04_RS05890 be485d5d87775c2036eea0567d839ff5 186 Pfam PF01765 Ribosome recycling factor 21 184 6.8E-63 T 26-04-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A4V04_RS03340 6dc85b2a4a41b0507e202ab56ae2ff29 369 TIGRFAM TIGR03837 efp_adjacent_2: conserved hypothetical protein, PP_1857 family 8 364 6.4E-117 T 26-04-2017 IPR016633 Uncharacterised conserved protein UCP015557 A4V04_RS03340 6dc85b2a4a41b0507e202ab56ae2ff29 369 PIRSF PIRSF015557 3 368 5.4E-117 T 26-04-2017 IPR016633 Uncharacterised conserved protein UCP015557 A4V04_RS03340 6dc85b2a4a41b0507e202ab56ae2ff29 369 Pfam PF10093 Uncharacterized protein conserved in bacteria (DUF2331) 8 363 2.3E-120 T 26-04-2017 IPR016633 Uncharacterised conserved protein UCP015557 A4V04_RS10510 c5c1a352377574f9bb96bc66cdbbfc8a 559 Gene3D G3DSA:1.10.275.10 26 226 3.2E-38 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS10510 c5c1a352377574f9bb96bc66cdbbfc8a 559 Gene3D G3DSA:1.20.200.10 230 548 4.7E-50 T 26-04-2017 A4V04_RS10510 c5c1a352377574f9bb96bc66cdbbfc8a 559 Pfam PF00221 Aromatic amino acid lyase 33 524 1.1E-87 T 26-04-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 A4V04_RS10510 c5c1a352377574f9bb96bc66cdbbfc8a 559 SUPERFAMILY SSF48557 7 550 5.1E-97 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS02285 b6b58e459cc97608ee10cfacdb4ddb5a 297 SUPERFAMILY SSF46785 4 81 2.11E-15 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02285 b6b58e459cc97608ee10cfacdb4ddb5a 297 Gene3D G3DSA:1.10.10.10 2 81 8.8E-19 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02285 b6b58e459cc97608ee10cfacdb4ddb5a 297 Pfam PF03466 LysR substrate binding domain 89 290 2.8E-11 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS02285 b6b58e459cc97608ee10cfacdb4ddb5a 297 SUPERFAMILY SSF53850 87 292 1.07E-13 T 26-04-2017 A4V04_RS02285 b6b58e459cc97608ee10cfacdb4ddb5a 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 60 2.2E-13 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS06985 f0f9b48831627966e863240bf901d7fe 118 SUPERFAMILY SSF101756 19 116 5.89E-28 T 26-04-2017 IPR005220 Bacterial OB-fold A4V04_RS06985 f0f9b48831627966e863240bf901d7fe 118 Pfam PF04076 Bacterial OB fold (BOF) protein 21 115 2.3E-23 T 26-04-2017 IPR005220 Bacterial OB-fold A4V04_RS06985 f0f9b48831627966e863240bf901d7fe 118 Gene3D G3DSA:2.40.50.200 16 118 1.9E-33 T 26-04-2017 IPR005220 Bacterial OB-fold A4V04_RS11805 3eb4c5dc509d2e0a076c621267e65756 70 Gene3D G3DSA:1.10.260.40 31 67 1.7E-4 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS11805 3eb4c5dc509d2e0a076c621267e65756 70 SUPERFAMILY SSF47413 18 68 3.18E-5 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS07290 597a92b716a0328f49cc8e7ce5e6b214 500 Pfam PF00939 Sodium:sulfate symporter transmembrane region 26 499 8.1E-101 T 26-04-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A4V04_RS07290 597a92b716a0328f49cc8e7ce5e6b214 500 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 43 494 1.8E-68 T 26-04-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A4V04_RS07290 597a92b716a0328f49cc8e7ce5e6b214 500 PIRSF PIRSF002457 11 500 1.2E-123 T 26-04-2017 IPR030676 Citrate carrier CitT-related A4V04_RS12555 ff1a04c18516672bbdb752b885bbb529 215 Gene3D G3DSA:1.10.510.10 86 160 8.8E-6 T 26-04-2017 A4V04_RS12555 ff1a04c18516672bbdb752b885bbb529 215 SUPERFAMILY SSF56112 44 161 3.51E-12 T 26-04-2017 IPR011009 Protein kinase-like domain A4V04_RS04325 856a8a14a9040f665631282cd4c3d0e9 409 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 11 404 6.5E-95 T 26-04-2017 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 A4V04_RS04325 856a8a14a9040f665631282cd4c3d0e9 409 Pfam PF03616 Sodium/glutamate symporter 11 378 1.2E-98 T 26-04-2017 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 A4V04_RS02985 42d077b855a5835b9c6234ec840b8cae 424 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 26-04-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4V04_RS02985 42d077b855a5835b9c6234ec840b8cae 424 SUPERFAMILY SSF52777 194 423 4.23E-86 T 26-04-2017 A4V04_RS02985 42d077b855a5835b9c6234ec840b8cae 424 Pfam PF02817 e3 binding domain 128 163 4.6E-12 T 26-04-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4V04_RS02985 42d077b855a5835b9c6234ec840b8cae 424 SUPERFAMILY SSF47005 126 166 5.75E-9 T 26-04-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4V04_RS02985 42d077b855a5835b9c6234ec840b8cae 424 Gene3D G3DSA:3.30.559.10 185 422 7.4E-90 T 26-04-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 A4V04_RS02985 42d077b855a5835b9c6234ec840b8cae 424 SUPERFAMILY SSF51230 2 97 1.44E-26 T 26-04-2017 IPR011053 Single hybrid motif A4V04_RS02985 42d077b855a5835b9c6234ec840b8cae 424 Pfam PF00364 Biotin-requiring enzyme 5 77 2.0E-21 T 26-04-2017 IPR000089 Biotin/lipoyl attachment A4V04_RS02985 42d077b855a5835b9c6234ec840b8cae 424 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 194 422 2.2E-79 T 26-04-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4V04_RS02985 42d077b855a5835b9c6234ec840b8cae 424 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 423 6.8E-161 T 26-04-2017 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A4V04_RS02985 42d077b855a5835b9c6234ec840b8cae 424 Gene3D G3DSA:2.40.50.100 2 97 5.6E-28 T 26-04-2017 A4V04_RS02985 42d077b855a5835b9c6234ec840b8cae 424 Gene3D G3DSA:4.10.320.10 127 173 6.5E-14 T 26-04-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4V04_RS03120 1804bd12ed04070bc508978b23c83057 300 Gene3D G3DSA:3.40.50.10490 113 274 3.0E-16 T 26-04-2017 A4V04_RS03120 1804bd12ed04070bc508978b23c83057 300 Pfam PF01418 Helix-turn-helix domain, rpiR family 19 88 8.6E-16 T 26-04-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A4V04_RS03120 1804bd12ed04070bc508978b23c83057 300 Gene3D G3DSA:1.10.10.10 17 86 7.5E-23 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS03120 1804bd12ed04070bc508978b23c83057 300 SUPERFAMILY SSF53697 110 272 7.12E-14 T 26-04-2017 A4V04_RS03120 1804bd12ed04070bc508978b23c83057 300 Pfam PF01380 SIS domain 139 264 4.7E-7 T 26-04-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4V04_RS03120 1804bd12ed04070bc508978b23c83057 300 SUPERFAMILY SSF46689 17 87 1.02E-17 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS01820 00d28e2afd7781eb91e4e62ec0d62df6 374 Pfam PF03743 Bacterial conjugation TrbI-like protein 170 368 3.0E-36 T 26-04-2017 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI A4V04_RS09010 47672772d5656baa9739de1f9ff4f2d6 199 Gene3D G3DSA:2.60.450.10 23 173 2.0E-28 T 26-04-2017 A4V04_RS09010 47672772d5656baa9739de1f9ff4f2d6 199 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 5 177 22.462 T 26-04-2017 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 A4V04_RS09010 47672772d5656baa9739de1f9ff4f2d6 199 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 22 176 1.1E-28 T 26-04-2017 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 A4V04_RS09010 47672772d5656baa9739de1f9ff4f2d6 199 Pfam PF03968 OstA-like protein 32 153 8.0E-17 T 26-04-2017 IPR005653 Organic solvent tolerance-like, N-terminal A4V04_RS08385 520c03daeb7a42a906ad65ccc0a7930e 256 Gene3D G3DSA:3.90.76.10 36 186 2.7E-28 T 26-04-2017 A4V04_RS08385 520c03daeb7a42a906ad65ccc0a7930e 256 Gene3D G3DSA:3.40.190.10 187 238 3.2E-10 T 26-04-2017 A4V04_RS08385 520c03daeb7a42a906ad65ccc0a7930e 256 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 67 238 9.8E-30 T 26-04-2017 IPR000914 Solute-binding protein family 5 domain A4V04_RS08385 520c03daeb7a42a906ad65ccc0a7930e 256 SUPERFAMILY SSF53850 25 238 1.09E-44 T 26-04-2017 A4V04_RS11720 462fc2dd137944d47a2a61a1c71203af 253 SUPERFAMILY SSF47598 62 105 5.28E-5 T 26-04-2017 IPR010985 Ribbon-helix-helix GO:0006355 A4V04_RS11720 462fc2dd137944d47a2a61a1c71203af 253 Pfam PF05713 Bacterial mobilisation protein (MobC) 189 226 1.5E-6 T 26-04-2017 IPR008687 Bacterial mobilisation A4V04_RS08070 a56ef3b8f2f6e3722ebb982edf126423 336 Pfam PF03601 Conserved hypothetical protein 698 15 316 4.9E-62 T 26-04-2017 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 137 682 2.4E-158 T 26-04-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 158 651 1.2E-74 T 26-04-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 SUPERFAMILY SSF81653 192 286 2.35E-21 T 26-04-2017 A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 SUPERFAMILY SSF56784 377 397 2.63E-48 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 SUPERFAMILY SSF56784 437 680 2.63E-48 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 Pfam PF00122 E1-E2 ATPase 159 370 2.8E-45 T 26-04-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 381 387 - T 26-04-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 Gene3D G3DSA:3.40.1110.10 394 507 6.3E-19 T 26-04-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 Pfam PF00702 haloacid dehalogenase-like hydrolase 375 595 4.0E-41 T 26-04-2017 A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 379 393 1.5E-23 T 26-04-2017 A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 581 600 1.5E-23 T 26-04-2017 A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 505 516 1.5E-23 T 26-04-2017 A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 604 616 1.5E-23 T 26-04-2017 A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 528 538 1.5E-23 T 26-04-2017 A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 237 251 1.5E-23 T 26-04-2017 A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 Gene3D G3DSA:3.40.50.1000 508 649 4.4E-45 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 Gene3D G3DSA:3.40.50.1000 353 393 4.4E-45 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS06045 5a514a6a07d18ab041ae6a3eabd65bce 698 Gene3D G3DSA:2.70.150.10 182 287 3.9E-21 T 26-04-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4V04_RS03925 086ef18dbfe76b7d83fd1763d9e9ca6a 300 Pfam PF11537 Protein of unknown function (DUF3227) 106 147 8.9E-5 T 26-04-2017 IPR021609 Protein of unknown function DUF3227 A4V04_RS03925 086ef18dbfe76b7d83fd1763d9e9ca6a 300 Gene3D G3DSA:3.90.1670.10 14 279 3.4E-40 T 26-04-2017 IPR024064 FdhE-like A4V04_RS03925 086ef18dbfe76b7d83fd1763d9e9ca6a 300 Pfam PF04216 Protein involved in formate dehydrogenase formation 22 266 3.3E-18 T 26-04-2017 IPR006452 Formate dehydrogenase accessory protein GO:0005737 A4V04_RS03925 086ef18dbfe76b7d83fd1763d9e9ca6a 300 SUPERFAMILY SSF144020 14 276 4.71E-30 T 26-04-2017 IPR024064 FdhE-like A4V04_RS06825 d4626d3bbf3a073ae05adb0bd41b2199 76 PRINTS PR00163 Rubredoxin signature 20 36 2.7E-9 T 26-04-2017 IPR024935 Rubredoxin domain GO:0005506 A4V04_RS06825 d4626d3bbf3a073ae05adb0bd41b2199 76 PRINTS PR00163 Rubredoxin signature 50 66 2.7E-9 T 26-04-2017 IPR024935 Rubredoxin domain GO:0005506 A4V04_RS06825 d4626d3bbf3a073ae05adb0bd41b2199 76 Gene3D G3DSA:2.20.28.10 17 69 7.0E-21 T 26-04-2017 IPR004039 Rubredoxin-type fold A4V04_RS06825 d4626d3bbf3a073ae05adb0bd41b2199 76 Pfam PF00301 Rubredoxin 22 66 3.3E-19 T 26-04-2017 IPR024935 Rubredoxin domain GO:0005506 A4V04_RS06825 d4626d3bbf3a073ae05adb0bd41b2199 76 SUPERFAMILY SSF57802 18 72 1.99E-18 T 26-04-2017 A4V04_RS06825 d4626d3bbf3a073ae05adb0bd41b2199 76 ProSitePatterns PS00202 Rubredoxin signature. 50 60 - T 26-04-2017 IPR018527 Rubredoxin, iron-binding site GO:0046872 A4V04_RS12260 ec5f19ccfd68c3cb9153e67505b1a1d7 177 Pfam PF04608 Phosphatidylglycerophosphatase A 21 158 5.6E-36 T 26-04-2017 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A4V04_RS12260 ec5f19ccfd68c3cb9153e67505b1a1d7 177 SUPERFAMILY SSF101307 14 157 7.32E-28 T 26-04-2017 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A4V04_RS12260 ec5f19ccfd68c3cb9153e67505b1a1d7 177 PIRSF PIRSF006162 9 168 3.7E-30 T 26-04-2017 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668 A4V04_RS01225 ebb03c66567e11ebfd374f52b969910e 424 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 57 417 2.3E-66 T 26-04-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A4V04_RS01225 ebb03c66567e11ebfd374f52b969910e 424 Gene3D G3DSA:1.20.1450.10 2 76 0.001 T 26-04-2017 IPR003393 Ammonia monooxygenase/particulate methane monooxygenase, subunit A A4V04_RS01225 ebb03c66567e11ebfd374f52b969910e 424 Pfam PF03606 C4-dicarboxylate anaerobic carrier 57 423 4.5E-24 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS03895 71f67dd6feb934ea5b048e0a18e73861 121 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 6 75 2.1E-25 T 26-04-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4V04_RS03895 71f67dd6feb934ea5b048e0a18e73861 121 PRINTS PR01651 Protein-export SecG membrane protein signature 57 79 7.8E-33 T 26-04-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4V04_RS03895 71f67dd6feb934ea5b048e0a18e73861 121 PRINTS PR01651 Protein-export SecG membrane protein signature 26 40 7.8E-33 T 26-04-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4V04_RS03895 71f67dd6feb934ea5b048e0a18e73861 121 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 7.8E-33 T 26-04-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4V04_RS03895 71f67dd6feb934ea5b048e0a18e73861 121 PRINTS PR01651 Protein-export SecG membrane protein signature 41 57 7.8E-33 T 26-04-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4V04_RS03895 71f67dd6feb934ea5b048e0a18e73861 121 Pfam PF03840 Preprotein translocase SecG subunit 8 75 3.3E-21 T 26-04-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4V04_RS05765 6740b91f567566099efecf6ca1d29d6f 149 Pfam PF14437 MafB19-like deaminase 1 142 4.1E-33 T 26-04-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A4V04_RS05765 6740b91f567566099efecf6ca1d29d6f 149 Gene3D G3DSA:3.40.140.10 1 141 2.2E-55 T 26-04-2017 A4V04_RS05765 6740b91f567566099efecf6ca1d29d6f 149 SUPERFAMILY SSF53927 1 144 2.68E-53 T 26-04-2017 IPR016193 Cytidine deaminase-like GO:0003824 A4V04_RS05765 6740b91f567566099efecf6ca1d29d6f 149 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 1 143 44.582 T 26-04-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A4V04_RS05765 6740b91f567566099efecf6ca1d29d6f 149 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 47 84 - T 26-04-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A4V04_RS01875 157e45e362d98eda719249c4d8f490c9 540 Gene3D G3DSA:3.40.50.410 365 501 1.0E-8 T 26-04-2017 IPR002035 von Willebrand factor, type A A4V04_RS01875 157e45e362d98eda719249c4d8f490c9 540 SMART SM00327 361 535 6.0E-5 T 26-04-2017 IPR002035 von Willebrand factor, type A A4V04_RS01875 157e45e362d98eda719249c4d8f490c9 540 Pfam PF00092 von Willebrand factor type A domain 366 502 3.0E-6 T 26-04-2017 IPR002035 von Willebrand factor, type A A4V04_RS01875 157e45e362d98eda719249c4d8f490c9 540 SUPERFAMILY SSF53300 365 515 1.38E-16 T 26-04-2017 IPR002035 von Willebrand factor, type A A4V04_RS01845 5fe0d79407d94f5bd0b69f6c453733ac 161 SUPERFAMILY SSF53955 21 141 6.02E-25 T 26-04-2017 IPR023346 Lysozyme-like domain A4V04_RS01845 5fe0d79407d94f5bd0b69f6c453733ac 161 Pfam PF01464 Transglycosylase SLT domain 27 128 4.7E-22 T 26-04-2017 IPR008258 Transglycosylase SLT domain 1 A4V04_RS01845 5fe0d79407d94f5bd0b69f6c453733ac 161 Gene3D G3DSA:1.10.530.10 24 156 1.3E-20 T 26-04-2017 A4V04_RS09810 08fa536b1360342c084692dd0dc4ddb5 95 SUPERFAMILY SSF141000 3 93 3.66E-29 T 26-04-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A4V04_RS09810 08fa536b1360342c084692dd0dc4ddb5 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 3.6E-21 T 26-04-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A4V04_RS09810 08fa536b1360342c084692dd0dc4ddb5 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 8.0E-30 T 26-04-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A4V04_RS09810 08fa536b1360342c084692dd0dc4ddb5 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 22.205 T 26-04-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A4V04_RS11950 b4149002514f0f94b29451ae55a39da8 132 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 26-04-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4V04_RS11950 b4149002514f0f94b29451ae55a39da8 132 Pfam PF00293 NUDIX domain 9 113 1.7E-17 T 26-04-2017 IPR000086 NUDIX hydrolase domain GO:0016787 A4V04_RS11950 b4149002514f0f94b29451ae55a39da8 132 PRINTS PR00502 NUDIX hydrolase family signature 36 50 4.0E-7 T 26-04-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4V04_RS11950 b4149002514f0f94b29451ae55a39da8 132 PRINTS PR00502 NUDIX hydrolase family signature 50 65 4.0E-7 T 26-04-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4V04_RS11950 b4149002514f0f94b29451ae55a39da8 132 Gene3D G3DSA:3.90.79.10 8 128 4.8E-29 T 26-04-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4V04_RS11950 b4149002514f0f94b29451ae55a39da8 132 SUPERFAMILY SSF55811 5 123 3.79E-31 T 26-04-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4V04_RS12870 4ab3d5e77634d1ea7170eab032c37b0d 260 Pfam PF13411 MerR HTH family regulatory protein 3 69 3.2E-9 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS12870 4ab3d5e77634d1ea7170eab032c37b0d 260 SMART SM00422 2 71 1.3E-12 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS12870 4ab3d5e77634d1ea7170eab032c37b0d 260 SUPERFAMILY SSF46955 2 104 4.53E-15 T 26-04-2017 IPR009061 Putative DNA-binding domain A4V04_RS12870 4ab3d5e77634d1ea7170eab032c37b0d 260 Gene3D G3DSA:3.20.80.10 193 259 6.8E-4 T 26-04-2017 IPR011256 Regulatory factor, effector binding domain A4V04_RS12870 4ab3d5e77634d1ea7170eab032c37b0d 260 Gene3D G3DSA:1.10.1660.10 1 68 1.6E-16 T 26-04-2017 A4V04_RS03510 24026851f88344791f0bf3766212946d 162 Pfam PF02674 Colicin V production protein 4 144 2.1E-32 T 26-04-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 A4V04_RS06805 7c372926ec33639098ea04cde9939a3a 210 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 8 154 9.0E-36 T 26-04-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A4V04_RS06805 7c372926ec33639098ea04cde9939a3a 210 Gene3D G3DSA:3.40.50.1450 7 161 2.0E-41 T 26-04-2017 IPR023430 Peptidase HybD-like domain A4V04_RS06805 7c372926ec33639098ea04cde9939a3a 210 Pfam PF01750 Hydrogenase maturation protease 24 152 5.8E-28 T 26-04-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A4V04_RS06805 7c372926ec33639098ea04cde9939a3a 210 TIGRFAM TIGR00140 hupD: hydrogenase expression/formation protein 8 158 2.3E-47 T 26-04-2017 IPR004419 Peptidase A31, hydrogenase expression/formation protein GO:0016485|GO:0046872 A4V04_RS06805 7c372926ec33639098ea04cde9939a3a 210 PRINTS PR00446 Hydrogen uptake protein signature 7 19 2.3E-22 T 26-04-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A4V04_RS06805 7c372926ec33639098ea04cde9939a3a 210 PRINTS PR00446 Hydrogen uptake protein signature 40 57 2.3E-22 T 26-04-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A4V04_RS06805 7c372926ec33639098ea04cde9939a3a 210 PRINTS PR00446 Hydrogen uptake protein signature 19 30 2.3E-22 T 26-04-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A4V04_RS06805 7c372926ec33639098ea04cde9939a3a 210 PRINTS PR00446 Hydrogen uptake protein signature 72 88 2.3E-22 T 26-04-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A4V04_RS06805 7c372926ec33639098ea04cde9939a3a 210 PRINTS PR00446 Hydrogen uptake protein signature 61 71 2.3E-22 T 26-04-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A4V04_RS06805 7c372926ec33639098ea04cde9939a3a 210 SUPERFAMILY SSF53163 6 162 3.4E-38 T 26-04-2017 IPR023430 Peptidase HybD-like domain A4V04_RS07685 957660397c2bbbb0d18140facb328c9e 70 Gene3D G3DSA:2.40.50.100 1 69 8.6E-28 T 26-04-2017 A4V04_RS07685 957660397c2bbbb0d18140facb328c9e 70 SUPERFAMILY SSF50331 1 69 4.13E-21 T 26-04-2017 IPR008995 Molybdate/tungstate binding, C-terminal A4V04_RS07685 957660397c2bbbb0d18140facb328c9e 70 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 69 2.3E-24 T 26-04-2017 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 A4V04_RS07685 957660397c2bbbb0d18140facb328c9e 70 Pfam PF03459 TOBE domain 4 66 1.4E-16 T 26-04-2017 IPR005116 Transport-associated OB, type 1 A4V04_RS03420 5fc51cb4d68a17d513a2a7245ca09344 177 Pfam PF13508 Acetyltransferase (GNAT) domain 48 137 1.4E-12 T 26-04-2017 IPR000182 GNAT domain GO:0008080 A4V04_RS03420 5fc51cb4d68a17d513a2a7245ca09344 177 SUPERFAMILY SSF55729 20 152 1.03E-16 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS03420 5fc51cb4d68a17d513a2a7245ca09344 177 Gene3D G3DSA:3.40.630.30 19 145 1.7E-20 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS12605 4d00506838030ffaeb15ce393612e563 196 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 26-04-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4V04_RS12605 4d00506838030ffaeb15ce393612e563 196 SUPERFAMILY SSF54211 3 87 1.64E-34 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS12605 4d00506838030ffaeb15ce393612e563 196 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 175 4.4E-64 T 26-04-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4V04_RS12605 4d00506838030ffaeb15ce393612e563 196 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 196 41.613 T 26-04-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4V04_RS12605 4d00506838030ffaeb15ce393612e563 196 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 157 169 - T 26-04-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4V04_RS12605 4d00506838030ffaeb15ce393612e563 196 Gene3D G3DSA:3.30.230.40 3 89 6.9E-39 T 26-04-2017 A4V04_RS12605 4d00506838030ffaeb15ce393612e563 196 SUPERFAMILY SSF54211 89 179 2.91E-32 T 26-04-2017 IPR020568 Ribosomal protein S5 domain 2-type fold A4V04_RS12605 4d00506838030ffaeb15ce393612e563 196 Gene3D G3DSA:3.30.230.40 91 196 3.2E-26 T 26-04-2017 A4V04_RS05840 8ff224798fffa0ea921b6a445584fdd3 384 Gene3D G3DSA:3.40.50.2000 213 292 1.0E-4 T 26-04-2017 A4V04_RS05840 8ff224798fffa0ea921b6a445584fdd3 384 SUPERFAMILY SSF53756 59 294 1.33E-24 T 26-04-2017 A4V04_RS05840 8ff224798fffa0ea921b6a445584fdd3 384 Pfam PF02684 Lipid-A-disaccharide synthetase 9 361 6.0E-95 T 26-04-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 A4V04_RS05840 8ff224798fffa0ea921b6a445584fdd3 384 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 6 382 34.217 T 26-04-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 A4V04_RS05840 8ff224798fffa0ea921b6a445584fdd3 384 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 7 381 1.8E-90 T 26-04-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 A4V04_RS06470 0724220f2366360b569661b21c8ed031 258 SUPERFAMILY SSF51306 163 251 4.71E-9 T 26-04-2017 IPR015927 Peptidase S24/S26A/S26B/S26C A4V04_RS10055 87b24b884608c1ec88d4ee1fb7a5bf36 423 Gene3D G3DSA:3.30.70.360 204 302 1.2E-16 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS10055 87b24b884608c1ec88d4ee1fb7a5bf36 423 SUPERFAMILY SSF55031 204 308 3.14E-15 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS10055 87b24b884608c1ec88d4ee1fb7a5bf36 423 Pfam PF07687 Peptidase dimerisation domain 201 300 2.2E-11 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS10055 87b24b884608c1ec88d4ee1fb7a5bf36 423 Gene3D G3DSA:3.40.630.10 303 406 1.0E-40 T 26-04-2017 A4V04_RS10055 87b24b884608c1ec88d4ee1fb7a5bf36 423 Gene3D G3DSA:3.40.630.10 42 193 1.0E-40 T 26-04-2017 A4V04_RS10055 87b24b884608c1ec88d4ee1fb7a5bf36 423 SUPERFAMILY SSF53187 38 216 6.83E-46 T 26-04-2017 A4V04_RS10055 87b24b884608c1ec88d4ee1fb7a5bf36 423 SUPERFAMILY SSF53187 322 410 6.83E-46 T 26-04-2017 A4V04_RS10055 87b24b884608c1ec88d4ee1fb7a5bf36 423 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 98 107 - T 26-04-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A4V04_RS10055 87b24b884608c1ec88d4ee1fb7a5bf36 423 Pfam PF01546 Peptidase family M20/M25/M40 99 397 2.0E-19 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS07010 03cc25e9465733f2b520eaa9fe565d75 203 SUPERFAMILY SSF111304 5 199 1.1E-65 T 26-04-2017 IPR023627 Recombination protein RecR A4V04_RS07010 03cc25e9465733f2b520eaa9fe565d75 203 Hamap MF_00017 Recombination protein RecR [recR]. 1 200 84.564 T 26-04-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A4V04_RS07010 03cc25e9465733f2b520eaa9fe565d75 203 TIGRFAM TIGR00615 recR: recombination protein RecR 5 198 5.1E-67 T 26-04-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A4V04_RS07010 03cc25e9465733f2b520eaa9fe565d75 203 Pfam PF02132 RecR protein 40 78 2.8E-13 T 26-04-2017 IPR023628 Recombination protein RecR, C4-type zinc finger A4V04_RS07010 03cc25e9465733f2b520eaa9fe565d75 203 Pfam PF13662 Toprim domain 81 173 2.4E-20 T 26-04-2017 IPR006171 Toprim domain A4V04_RS07010 03cc25e9465733f2b520eaa9fe565d75 203 SMART SM00493 80 165 8.4E-5 T 26-04-2017 IPR006171 Toprim domain A4V04_RS13120 039f3035dde7318f6606aeaea7393e3a 442 Pfam PF01385 Probable transposase 191 292 3.7E-14 T 26-04-2017 IPR001959 Probable transposase, IS891/IS1136/IS1341 A4V04_RS13120 039f3035dde7318f6606aeaea7393e3a 442 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 260 340 5.3E-20 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS13120 039f3035dde7318f6606aeaea7393e3a 442 Pfam PF07282 Putative transposase DNA-binding domain 313 391 2.6E-8 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS04990 1111ac5475aadf6e29033f4804090bb3 418 Pfam PF01546 Peptidase family M20/M25/M40 83 376 3.0E-22 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS04990 1111ac5475aadf6e29033f4804090bb3 418 Gene3D G3DSA:3.40.630.10 310 376 4.5E-42 T 26-04-2017 A4V04_RS04990 1111ac5475aadf6e29033f4804090bb3 418 Gene3D G3DSA:3.40.630.10 15 186 4.5E-42 T 26-04-2017 A4V04_RS04990 1111ac5475aadf6e29033f4804090bb3 418 SUPERFAMILY SSF55031 187 284 1.48E-12 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS04990 1111ac5475aadf6e29033f4804090bb3 418 Pfam PF07687 Peptidase dimerisation domain 186 273 1.2E-12 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS04990 1111ac5475aadf6e29033f4804090bb3 418 SUPERFAMILY SSF53187 307 393 6.56E-45 T 26-04-2017 A4V04_RS04990 1111ac5475aadf6e29033f4804090bb3 418 SUPERFAMILY SSF53187 23 199 6.56E-45 T 26-04-2017 A4V04_RS04990 1111ac5475aadf6e29033f4804090bb3 418 Gene3D G3DSA:3.30.70.360 187 283 1.3E-13 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS07235 8d49308ffa96e3f8056223bd6e76db4a 304 SUPERFAMILY SSF56091 18 197 3.6E-8 T 26-04-2017 A4V04_RS07235 8d49308ffa96e3f8056223bd6e76db4a 304 Pfam PF09414 RNA ligase 18 196 9.8E-10 T 26-04-2017 IPR021122 RNA ligase domain, REL/Rln2 A4V04_RS02535 ad84bf5c4226350965822b68cdf4a295 469 Pfam PF01979 Amidohydrolase family 52 420 1.9E-16 T 26-04-2017 IPR006680 Amidohydrolase-related GO:0016787 A4V04_RS02535 ad84bf5c4226350965822b68cdf4a295 469 SUPERFAMILY SSF51556 55 244 2.04E-13 T 26-04-2017 IPR032466 Metal-dependent hydrolase A4V04_RS02535 ad84bf5c4226350965822b68cdf4a295 469 SUPERFAMILY SSF51556 306 392 2.04E-13 T 26-04-2017 IPR032466 Metal-dependent hydrolase A4V04_RS02535 ad84bf5c4226350965822b68cdf4a295 469 Gene3D G3DSA:3.20.20.140 342 418 8.8E-17 T 26-04-2017 A4V04_RS02535 ad84bf5c4226350965822b68cdf4a295 469 Gene3D G3DSA:3.20.20.140 62 285 8.8E-17 T 26-04-2017 A4V04_RS02535 ad84bf5c4226350965822b68cdf4a295 469 SUPERFAMILY SSF51338 1 55 4.33E-19 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS02535 ad84bf5c4226350965822b68cdf4a295 469 SUPERFAMILY SSF51338 392 431 4.33E-19 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS02535 ad84bf5c4226350965822b68cdf4a295 469 Gene3D G3DSA:2.30.40.10 2 61 3.8E-16 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS06640 c30b60202aa2bfb7bcdbf3e57fb685e2 254 Gene3D G3DSA:3.40.190.10 35 114 4.4E-47 T 26-04-2017 A4V04_RS06640 c30b60202aa2bfb7bcdbf3e57fb685e2 254 Gene3D G3DSA:3.40.190.10 216 253 4.4E-47 T 26-04-2017 A4V04_RS06640 c30b60202aa2bfb7bcdbf3e57fb685e2 254 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 60 73 - T 26-04-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 A4V04_RS06640 c30b60202aa2bfb7bcdbf3e57fb685e2 254 SMART SM00062 37 254 3.0E-75 T 26-04-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4V04_RS06640 c30b60202aa2bfb7bcdbf3e57fb685e2 254 SMART SM00079 37 254 9.1E-10 T 26-04-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A4V04_RS06640 c30b60202aa2bfb7bcdbf3e57fb685e2 254 Gene3D G3DSA:3.40.190.10 115 215 2.4E-29 T 26-04-2017 A4V04_RS06640 c30b60202aa2bfb7bcdbf3e57fb685e2 254 SUPERFAMILY SSF53850 4 253 5.18E-77 T 26-04-2017 A4V04_RS06640 c30b60202aa2bfb7bcdbf3e57fb685e2 254 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 253 1.2E-71 T 26-04-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4V04_RS09390 cac31fb7b5596cbd4b6c5ce19632fc79 380 Gene3D G3DSA:3.20.20.140 63 333 4.8E-106 T 26-04-2017 A4V04_RS09390 cac31fb7b5596cbd4b6c5ce19632fc79 380 Pfam PF01979 Amidohydrolase family 51 364 2.6E-10 T 26-04-2017 IPR006680 Amidohydrolase-related GO:0016787 A4V04_RS09390 cac31fb7b5596cbd4b6c5ce19632fc79 380 PIRSF PIRSF001238 1 380 3.6E-139 T 26-04-2017 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 A4V04_RS09390 cac31fb7b5596cbd4b6c5ce19632fc79 380 Gene3D G3DSA:2.30.40.10 3 62 3.1E-16 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS09390 cac31fb7b5596cbd4b6c5ce19632fc79 380 SUPERFAMILY SSF51556 55 337 2.2E-66 T 26-04-2017 IPR032466 Metal-dependent hydrolase A4V04_RS09390 cac31fb7b5596cbd4b6c5ce19632fc79 380 SUPERFAMILY SSF51338 1 54 2.4E-20 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS09390 cac31fb7b5596cbd4b6c5ce19632fc79 380 SUPERFAMILY SSF51338 337 378 2.4E-20 T 26-04-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4V04_RS09390 cac31fb7b5596cbd4b6c5ce19632fc79 380 TIGRFAM TIGR01975 isoAsp_dipep: beta-aspartyl peptidase 4 379 7.0E-124 T 26-04-2017 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 A4V04_RS10795 6be598f933cbee9c03939663ec251748 478 SMART SM00345 18 77 1.2E-5 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS10795 6be598f933cbee9c03939663ec251748 478 Gene3D G3DSA:3.40.640.10 151 363 1.1E-24 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS10795 6be598f933cbee9c03939663ec251748 478 SUPERFAMILY SSF53383 150 466 8.66E-38 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS10795 6be598f933cbee9c03939663ec251748 478 SMART SM00419 32 79 0.0062 T 26-04-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4V04_RS10795 6be598f933cbee9c03939663ec251748 478 Gene3D G3DSA:3.90.1150.10 364 464 4.8E-5 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS10795 6be598f933cbee9c03939663ec251748 478 Gene3D G3DSA:1.10.10.10 4 76 1.4E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS10795 6be598f933cbee9c03939663ec251748 478 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 9.5E-7 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS10795 6be598f933cbee9c03939663ec251748 478 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 9.5E-7 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS10795 6be598f933cbee9c03939663ec251748 478 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 75 6.3E-10 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS10795 6be598f933cbee9c03939663ec251748 478 SUPERFAMILY SSF46785 7 87 1.21E-15 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07055 1180ac60b424198857613a9456586816 462 TIGRFAM TIGR00797 matE: MATE efflux family protein 24 428 1.7E-69 T 26-04-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4V04_RS07055 1180ac60b424198857613a9456586816 462 Pfam PF01554 MatE 24 182 3.2E-24 T 26-04-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4V04_RS07055 1180ac60b424198857613a9456586816 462 Pfam PF01554 MatE 249 404 3.8E-26 T 26-04-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4V04_RS07055 1180ac60b424198857613a9456586816 462 PIRSF PIRSF006603 15 459 2.3E-51 T 26-04-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4V04_RS08045 1030f36cb65e389324119248dd5892f4 135 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 24 113 1.6E-36 T 26-04-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 A4V04_RS08045 1030f36cb65e389324119248dd5892f4 135 Gene3D G3DSA:3.10.50.40 9 122 5.7E-50 T 26-04-2017 A4V04_RS08045 1030f36cb65e389324119248dd5892f4 135 SUPERFAMILY SSF54534 11 115 1.47E-43 T 26-04-2017 A4V04_RS05000 27332356fd39b17dd0fc8557e3b76f9b 443 SUPERFAMILY SSF161070 4 442 1.31E-128 T 26-04-2017 A4V04_RS05000 27332356fd39b17dd0fc8557e3b76f9b 443 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 86 112 1.1E-16 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS05000 27332356fd39b17dd0fc8557e3b76f9b 443 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 423 443 1.1E-16 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS05000 27332356fd39b17dd0fc8557e3b76f9b 443 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 1.1E-16 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS05000 27332356fd39b17dd0fc8557e3b76f9b 443 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 1.1E-16 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS05000 27332356fd39b17dd0fc8557e3b76f9b 443 Pfam PF00209 Sodium:neurotransmitter symporter family 148 442 1.2E-32 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS05000 27332356fd39b17dd0fc8557e3b76f9b 443 Pfam PF00209 Sodium:neurotransmitter symporter family 4 119 4.8E-26 T 26-04-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A4V04_RS06710 6efea476a0928afbe5274048e253b605 259 Gene3D G3DSA:3.20.20.140 1 253 1.4E-87 T 26-04-2017 A4V04_RS06710 6efea476a0928afbe5274048e253b605 259 SUPERFAMILY SSF51556 1 254 3.32E-87 T 26-04-2017 IPR032466 Metal-dependent hydrolase A4V04_RS06710 6efea476a0928afbe5274048e253b605 259 PIRSF PIRSF005902 1 257 1.4E-77 T 26-04-2017 IPR001130 TatD family GO:0016788 A4V04_RS06710 6efea476a0928afbe5274048e253b605 259 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 124 134 - T 26-04-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A4V04_RS06710 6efea476a0928afbe5274048e253b605 259 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 26-04-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A4V04_RS06710 6efea476a0928afbe5274048e253b605 259 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 26-04-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A4V04_RS06710 6efea476a0928afbe5274048e253b605 259 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 2.4E-86 T 26-04-2017 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A4V04_RS06710 6efea476a0928afbe5274048e253b605 259 Pfam PF01026 TatD related DNase 3 253 9.9E-77 T 26-04-2017 IPR001130 TatD family GO:0016788 A4V04_RS06485 51e0c2714c465504e283959d84fb4516 255 SUPERFAMILY SSF52540 73 236 3.95E-20 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06485 51e0c2714c465504e283959d84fb4516 255 Pfam PF01695 IstB-like ATP binding protein 106 244 9.6E-24 T 26-04-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 A4V04_RS06485 51e0c2714c465504e283959d84fb4516 255 Gene3D G3DSA:3.40.50.300 60 244 2.5E-36 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10130 f6c11756da32cc326430bbf019dfffbe 376 Pfam PF13609 Gram-negative porin 8 348 8.7E-35 T 26-04-2017 A4V04_RS10130 f6c11756da32cc326430bbf019dfffbe 376 SUPERFAMILY SSF56935 21 376 5.19E-45 T 26-04-2017 A4V04_RS10130 f6c11756da32cc326430bbf019dfffbe 376 Gene3D G3DSA:2.40.160.10 22 376 1.4E-53 T 26-04-2017 IPR023614 Porin domain A4V04_RS09195 6b573a196ff8cda1264f4f946541c23d 347 Gene3D G3DSA:3.90.10.10 71 144 1.6E-8 T 26-04-2017 A4V04_RS09195 6b573a196ff8cda1264f4f946541c23d 347 SUPERFAMILY SSF48695 77 171 7.77E-17 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS09195 6b573a196ff8cda1264f4f946541c23d 347 SUPERFAMILY SSF48695 205 335 7.77E-17 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS11220 ebbac22bd688094d99de2a9cccde50b0 347 SUPERFAMILY SSF143631 27 332 4.71E-87 T 26-04-2017 IPR003374 ApbE-like domain A4V04_RS11220 ebbac22bd688094d99de2a9cccde50b0 347 PIRSF PIRSF006268 1 339 4.6E-92 T 26-04-2017 IPR024932 Flavin transferase ApbE GO:0017013 A4V04_RS11220 ebbac22bd688094d99de2a9cccde50b0 347 Pfam PF02424 ApbE family 36 312 8.5E-76 T 26-04-2017 IPR024932 Flavin transferase ApbE GO:0017013 A4V04_RS05365 5724a213302ca43eaeaa696c1e80584a 327 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 232 3.6E-20 T 26-04-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4V04_RS05365 5724a213302ca43eaeaa696c1e80584a 327 Gene3D G3DSA:3.40.50.720 4 313 8.1E-39 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS05365 5724a213302ca43eaeaa696c1e80584a 327 SUPERFAMILY SSF51735 4 314 1.35E-47 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS11290 690f090e9c7f22811fb964810d4f552a 101 Gene3D G3DSA:4.10.830.10 41 101 3.3E-27 T 26-04-2017 A4V04_RS11290 690f090e9c7f22811fb964810d4f552a 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.438 T 26-04-2017 IPR023036 Ribosomal protein S14, bacterial/plastid A4V04_RS11290 690f090e9c7f22811fb964810d4f552a 101 SUPERFAMILY SSF57716 2 101 1.43E-34 T 26-04-2017 A4V04_RS11290 690f090e9c7f22811fb964810d4f552a 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 1.3E-23 T 26-04-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS08020 8a5ffce6637ab9be219706335d583280 155 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 154 26.627 T 26-04-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS08020 8a5ffce6637ab9be219706335d583280 155 Pfam PF02590 Predicted SPOUT methyltransferase 1 153 3.8E-49 T 26-04-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS08020 8a5ffce6637ab9be219706335d583280 155 PIRSF PIRSF004505 1 154 1.9E-46 T 26-04-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4V04_RS08020 8a5ffce6637ab9be219706335d583280 155 Gene3D G3DSA:3.40.1280.10 1 154 6.6E-53 T 26-04-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4V04_RS08020 8a5ffce6637ab9be219706335d583280 155 SUPERFAMILY SSF75217 1 153 1.78E-46 T 26-04-2017 IPR029028 Alpha/beta knot methyltransferases A4V04_RS09505 43cda4ed4fe339aa80ed9714826ab7c7 274 Pfam PF12849 PBP superfamily domain 26 256 1.0E-40 T 26-04-2017 IPR024370 PBP domain A4V04_RS09505 43cda4ed4fe339aa80ed9714826ab7c7 274 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 19 273 1.1E-80 T 26-04-2017 IPR011862 Phosphate binding protein GO:0006810 A4V04_RS09505 43cda4ed4fe339aa80ed9714826ab7c7 274 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 35 - T 26-04-2017 IPR010916 TonB box, conserved site A4V04_RS09505 43cda4ed4fe339aa80ed9714826ab7c7 274 SUPERFAMILY SSF53850 29 273 3.67E-77 T 26-04-2017 A4V04_RS09505 43cda4ed4fe339aa80ed9714826ab7c7 274 Gene3D G3DSA:3.40.190.10 235 272 1.1E-11 T 26-04-2017 A4V04_RS09505 43cda4ed4fe339aa80ed9714826ab7c7 274 Gene3D G3DSA:3.40.190.10 2 117 1.1E-11 T 26-04-2017 A4V04_RS09505 43cda4ed4fe339aa80ed9714826ab7c7 274 Gene3D G3DSA:3.40.190.10 118 234 5.5E-45 T 26-04-2017 A4V04_RS04645 7fc6da181a7fa8baf76a5c3b6b258194 467 Gene3D G3DSA:3.30.465.10 101 220 1.8E-35 T 26-04-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4V04_RS04645 7fc6da181a7fa8baf76a5c3b6b258194 467 SUPERFAMILY SSF55103 193 467 1.96E-48 T 26-04-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4V04_RS04645 7fc6da181a7fa8baf76a5c3b6b258194 467 Pfam PF01565 FAD binding domain 42 180 5.7E-32 T 26-04-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4V04_RS04645 7fc6da181a7fa8baf76a5c3b6b258194 467 SUPERFAMILY SSF56176 5 220 6.04E-70 T 26-04-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4V04_RS04645 7fc6da181a7fa8baf76a5c3b6b258194 467 Gene3D G3DSA:3.30.43.10 6 98 2.0E-23 T 26-04-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A4V04_RS04645 7fc6da181a7fa8baf76a5c3b6b258194 467 Gene3D G3DSA:1.10.45.10 427 466 4.7E-12 T 26-04-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A4V04_RS04645 7fc6da181a7fa8baf76a5c3b6b258194 467 Pfam PF02913 FAD linked oxidases, C-terminal domain 219 466 4.3E-45 T 26-04-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4V04_RS10845 ffb0e2675d28fd1a23841e5d16fb5a28 48 Pfam PF08085 Entericidin EcnA/B family 21 41 3.7E-7 T 26-04-2017 IPR012556 Entericidin A/B GO:0009636|GO:0016020 A4V04_RS11350 5534ece5293607d4e269031bb54c5025 344 SUPERFAMILY SSF56553 53 177 8.55E-36 T 26-04-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11350 5534ece5293607d4e269031bb54c5025 344 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 267 323 1.5E-24 T 26-04-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11350 5534ece5293607d4e269031bb54c5025 344 SUPERFAMILY SSF55257 178 231 1.67E-28 T 26-04-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11350 5534ece5293607d4e269031bb54c5025 344 SUPERFAMILY SSF55257 10 53 1.67E-28 T 26-04-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11350 5534ece5293607d4e269031bb54c5025 344 Gene3D G3DSA:3.30.1360.10 11 64 2.4E-8 T 26-04-2017 A4V04_RS11350 5534ece5293607d4e269031bb54c5025 344 SMART SM00662 23 233 1.2E-80 T 26-04-2017 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11350 5534ece5293607d4e269031bb54c5025 344 Gene3D G3DSA:2.170.120.12 65 176 3.4E-36 T 26-04-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11350 5534ece5293607d4e269031bb54c5025 344 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 333 33.102 T 26-04-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11350 5534ece5293607d4e269031bb54c5025 344 SUPERFAMILY SSF47789 267 339 1.57E-25 T 26-04-2017 A4V04_RS11350 5534ece5293607d4e269031bb54c5025 344 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 64 152 6.4E-21 T 26-04-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11350 5534ece5293607d4e269031bb54c5025 344 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 24 332 1.7E-96 T 26-04-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11350 5534ece5293607d4e269031bb54c5025 344 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 29 227 6.4E-20 T 26-04-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11350 5534ece5293607d4e269031bb54c5025 344 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 272 342 4.0E-31 T 26-04-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4V04_RS11350 5534ece5293607d4e269031bb54c5025 344 Gene3D G3DSA:1.10.150.20 263 339 2.2E-33 T 26-04-2017 A4V04_RS07200 78c9c6a174f7a01fe8fdd5dd5337ddff 183 SUPERFAMILY SSF158710 24 166 1.06E-43 T 26-04-2017 A4V04_RS07200 78c9c6a174f7a01fe8fdd5dd5337ddff 183 Pfam PF04751 Protein of unknown function (DUF615) 13 162 2.6E-49 T 26-04-2017 IPR006839 Ribosome-associated, YjgA A4V04_RS07200 78c9c6a174f7a01fe8fdd5dd5337ddff 183 Gene3D G3DSA:1.10.60.30 24 96 2.3E-23 T 26-04-2017 IPR023153 PSPTO4464-like domain A4V04_RS07200 78c9c6a174f7a01fe8fdd5dd5337ddff 183 PIRSF PIRSF016183 1 168 4.6E-57 T 26-04-2017 IPR006839 Ribosome-associated, YjgA A4V04_RS07200 78c9c6a174f7a01fe8fdd5dd5337ddff 183 Gene3D G3DSA:1.10.60.30 100 165 3.6E-27 T 26-04-2017 IPR023153 PSPTO4464-like domain A4V04_RS08650 4d00905d892d31d5595b0a12f86e01dd 243 SMART SM00563 77 192 3.9E-31 T 26-04-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4V04_RS08650 4d00905d892d31d5595b0a12f86e01dd 243 SUPERFAMILY SSF69593 7 241 1.06E-44 T 26-04-2017 A4V04_RS08650 4d00905d892d31d5595b0a12f86e01dd 243 Gene3D G3DSA:3.40.1130.10 60 236 3.8E-26 T 26-04-2017 A4V04_RS08650 4d00905d892d31d5595b0a12f86e01dd 243 Pfam PF01553 Acyltransferase 63 189 4.0E-20 T 26-04-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4V04_RS13040 ec695fac29cc467de965b1627804f3b7 527 SUPERFAMILY SSF51905 24 285 1.06E-40 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS13040 ec695fac29cc467de965b1627804f3b7 527 SUPERFAMILY SSF51905 466 522 1.06E-40 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS13040 ec695fac29cc467de965b1627804f3b7 527 SUPERFAMILY SSF56425 287 466 1.26E-25 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS13040 ec695fac29cc467de965b1627804f3b7 527 Gene3D G3DSA:3.90.700.10 290 458 1.7E-26 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS13040 ec695fac29cc467de965b1627804f3b7 527 Gene3D G3DSA:3.50.50.60 27 274 5.7E-59 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS13040 ec695fac29cc467de965b1627804f3b7 527 Gene3D G3DSA:3.50.50.60 463 523 5.7E-59 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS13040 ec695fac29cc467de965b1627804f3b7 527 Pfam PF00890 FAD binding domain 41 505 9.0E-55 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS01455 18315ab35bfe4dcaad349be3d420303c 216 Gene3D G3DSA:3.40.50.1000 77 212 8.6E-32 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS01455 18315ab35bfe4dcaad349be3d420303c 216 Gene3D G3DSA:1.10.150.240 18 76 8.8E-9 T 26-04-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 A4V04_RS01455 18315ab35bfe4dcaad349be3d420303c 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 183 1.2E-25 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS01455 18315ab35bfe4dcaad349be3d420303c 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 102 177 6.8E-8 T 26-04-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4V04_RS01455 18315ab35bfe4dcaad349be3d420303c 216 SUPERFAMILY SSF56784 1 211 1.49E-45 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS05590 3b6a1c340c20ba2433240e8e772dca4e 373 Pfam PF01420 Type I restriction modification DNA specificity domain 13 167 7.6E-17 T 26-04-2017 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A4V04_RS05590 3b6a1c340c20ba2433240e8e772dca4e 373 Pfam PF01420 Type I restriction modification DNA specificity domain 200 353 2.8E-10 T 26-04-2017 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A4V04_RS05590 3b6a1c340c20ba2433240e8e772dca4e 373 SUPERFAMILY SSF116734 13 173 1.16E-5 T 26-04-2017 A4V04_RS05245 dbaad5d336c852b0cd30478866ffe7bf 264 SUPERFAMILY SSF109998 21 156 5.1E-11 T 26-04-2017 IPR027304 Trigger factor/SurA domain A4V04_RS05245 dbaad5d336c852b0cd30478866ffe7bf 264 Gene3D G3DSA:3.10.50.40 124 243 8.9E-26 T 26-04-2017 A4V04_RS05245 dbaad5d336c852b0cd30478866ffe7bf 264 Pfam PF13616 PPIC-type PPIASE domain 116 220 1.2E-15 T 26-04-2017 A4V04_RS05245 dbaad5d336c852b0cd30478866ffe7bf 264 SUPERFAMILY SSF54534 126 221 1.31E-19 T 26-04-2017 A4V04_RS07365 9b04df8eedd795ad633d3796e6bced90 238 SUPERFAMILY SSF51735 1 129 1.23E-22 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS07365 9b04df8eedd795ad633d3796e6bced90 238 Pfam PF02254 TrkA-N domain 3 118 3.6E-17 T 26-04-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4V04_RS07365 9b04df8eedd795ad633d3796e6bced90 238 Gene3D G3DSA:3.40.50.720 1 131 1.4E-24 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS00535 a892a1cd8796c9eff865ba52dba0e574 352 Pfam PF09950 Uncharacterized protein conserved in bacteria (DUF2184) 140 288 1.3E-8 T 26-04-2017 IPR020049 Protein of unknown function DUF2184 A4V04_RS07285 ff3ce43ee49d6a94fae92123c011625d 467 SUPERFAMILY SSF46689 6 58 2.33E-6 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS07285 ff3ce43ee49d6a94fae92123c011625d 467 Pfam PF01527 Transposase 5 58 1.5E-9 T 26-04-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4V04_RS07285 ff3ce43ee49d6a94fae92123c011625d 467 Gene3D G3DSA:1.10.10.60 11 74 4.3E-6 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS06690 37f1697c2f6c731b9d68e9b466a4628e 182 Gene3D G3DSA:1.25.40.10 45 172 6.8E-24 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS06690 37f1697c2f6c731b9d68e9b466a4628e 182 Pfam PF13432 Tetratricopeptide repeat 46 101 2.7E-6 T 26-04-2017 A4V04_RS06690 37f1697c2f6c731b9d68e9b466a4628e 182 SMART SM00028 70 103 14.0 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS06690 37f1697c2f6c731b9d68e9b466a4628e 182 SMART SM00028 104 137 0.14 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS06690 37f1697c2f6c731b9d68e9b466a4628e 182 SMART SM00028 138 166 120.0 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS06690 37f1697c2f6c731b9d68e9b466a4628e 182 Pfam PF13181 Tetratricopeptide repeat 104 135 4.0E-4 T 26-04-2017 IPR019734 Tetratricopeptide repeat GO:0005515 A4V04_RS06690 37f1697c2f6c731b9d68e9b466a4628e 182 SUPERFAMILY SSF48452 44 169 3.25E-21 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS01675 9fc24b56bd5abbb09238792f7f220a7e 86 Pfam PF13391 HNH endonuclease 11 37 4.5E-5 T 26-04-2017 IPR003615 HNH nuclease A4V04_RS07045 752348c54b73bf2d1512176bc0d466a8 98 PRINTS PR01249 Ribosomal protein L31 signature 2 19 7.9E-15 T 26-04-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS07045 752348c54b73bf2d1512176bc0d466a8 98 PRINTS PR01249 Ribosomal protein L31 signature 59 77 7.9E-15 T 26-04-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS07045 752348c54b73bf2d1512176bc0d466a8 98 PRINTS PR01249 Ribosomal protein L31 signature 44 59 7.9E-15 T 26-04-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS07045 752348c54b73bf2d1512176bc0d466a8 98 Pfam PF01197 Ribosomal protein L31 1 78 4.6E-27 T 26-04-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS07045 752348c54b73bf2d1512176bc0d466a8 98 TIGRFAM TIGR00105 L31: ribosomal protein bL31 44 79 6.4E-12 T 26-04-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS07045 752348c54b73bf2d1512176bc0d466a8 98 ProSitePatterns PS01143 Ribosomal protein L31 signature. 48 69 - T 26-04-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS07045 752348c54b73bf2d1512176bc0d466a8 98 SUPERFAMILY SSF143800 1 78 4.71E-20 T 26-04-2017 A4V04_RS10595 8b3a5456a51596c3ca0bcd9656cefb57 122 SUPERFAMILY SSF55298 3 121 1.15E-29 T 26-04-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4V04_RS10595 8b3a5456a51596c3ca0bcd9656cefb57 122 Gene3D G3DSA:3.30.1330.40 2 121 1.2E-28 T 26-04-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4V04_RS10595 8b3a5456a51596c3ca0bcd9656cefb57 122 Pfam PF01042 Endoribonuclease L-PSP 10 119 8.2E-26 T 26-04-2017 IPR006175 YjgF/YER057c/UK114 family A4V04_RS02745 a3163fd8f6c7e88bd305c45e7169f880 339 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 3 324 48.928 T 26-04-2017 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 A4V04_RS02745 a3163fd8f6c7e88bd305c45e7169f880 339 SUPERFAMILY SSF51395 8 304 7.69E-72 T 26-04-2017 A4V04_RS02745 a3163fd8f6c7e88bd305c45e7169f880 339 Pfam PF01207 Dihydrouridine synthase (Dus) 11 314 1.1E-83 T 26-04-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4V04_RS02745 a3163fd8f6c7e88bd305c45e7169f880 339 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 90 108 - T 26-04-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4V04_RS02745 a3163fd8f6c7e88bd305c45e7169f880 339 PIRSF PIRSF006621 2 323 2.8E-78 T 26-04-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4V04_RS02745 a3163fd8f6c7e88bd305c45e7169f880 339 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 8 318 2.3E-135 T 26-04-2017 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 A4V04_RS02745 a3163fd8f6c7e88bd305c45e7169f880 339 Gene3D G3DSA:3.20.20.70 8 251 1.5E-74 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS09730 2113c128d7b6381b3f3ac573f8971a8a 315 Pfam PF01145 SPFH domain / Band 7 family 32 202 2.3E-32 T 26-04-2017 IPR001107 Band 7 domain A4V04_RS09730 2113c128d7b6381b3f3ac573f8971a8a 315 PRINTS PR00721 Stomatin signature 35 57 1.1E-31 T 26-04-2017 IPR001972 Stomatin family GO:0016020 A4V04_RS09730 2113c128d7b6381b3f3ac573f8971a8a 315 PRINTS PR00721 Stomatin signature 83 104 1.1E-31 T 26-04-2017 IPR001972 Stomatin family GO:0016020 A4V04_RS09730 2113c128d7b6381b3f3ac573f8971a8a 315 PRINTS PR00721 Stomatin signature 118 135 1.1E-31 T 26-04-2017 IPR001972 Stomatin family GO:0016020 A4V04_RS09730 2113c128d7b6381b3f3ac573f8971a8a 315 PRINTS PR00721 Stomatin signature 138 161 1.1E-31 T 26-04-2017 IPR001972 Stomatin family GO:0016020 A4V04_RS09730 2113c128d7b6381b3f3ac573f8971a8a 315 PRINTS PR00721 Stomatin signature 162 180 1.1E-31 T 26-04-2017 IPR001972 Stomatin family GO:0016020 A4V04_RS09730 2113c128d7b6381b3f3ac573f8971a8a 315 PRINTS PR00721 Stomatin signature 181 202 1.1E-31 T 26-04-2017 IPR001972 Stomatin family GO:0016020 A4V04_RS09730 2113c128d7b6381b3f3ac573f8971a8a 315 Pfam PF16200 C-terminal region of band_7 251 312 1.2E-26 T 26-04-2017 IPR032435 Band 7, C-terminal extension A4V04_RS09730 2113c128d7b6381b3f3ac573f8971a8a 315 SUPERFAMILY SSF117892 59 193 1.44E-40 T 26-04-2017 IPR001107 Band 7 domain A4V04_RS09730 2113c128d7b6381b3f3ac573f8971a8a 315 SMART SM00244 28 186 1.5E-61 T 26-04-2017 IPR001107 Band 7 domain A4V04_RS04420 5cab96073bc41273ad00bba98bae0b83 154 Gene3D G3DSA:3.40.30.10 5 152 5.7E-46 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS04420 5cab96073bc41273ad00bba98bae0b83 154 SUPERFAMILY SSF52833 6 152 6.91E-45 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS04420 5cab96073bc41273ad00bba98bae0b83 154 Pfam PF00578 AhpC/TSA family 6 134 1.1E-35 T 26-04-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4V04_RS04420 5cab96073bc41273ad00bba98bae0b83 154 PIRSF PIRSF000239 1 143 8.5E-24 T 26-04-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4V04_RS12225 675cc9e61f4f2f60872674acad93308c 138 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 12 124 2.2E-10 T 26-04-2017 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III A4V04_RS02710 d724651163a4e06b21f3238994b53d3a 189 Gene3D G3DSA:2.30.30.180 82 135 6.7E-7 T 26-04-2017 IPR028998 Ribosome maturation factor RimP, C-terminal A4V04_RS02710 d724651163a4e06b21f3238994b53d3a 189 Pfam PF02576 Putative ribosome maturation factor RimP 10 139 2.8E-29 T 26-04-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 A4V04_RS02710 d724651163a4e06b21f3238994b53d3a 189 SUPERFAMILY SSF74942 78 151 4.18E-8 T 26-04-2017 IPR028998 Ribosome maturation factor RimP, C-terminal A4V04_RS02710 d724651163a4e06b21f3238994b53d3a 189 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 5 183 23.2 T 26-04-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 A4V04_RS02710 d724651163a4e06b21f3238994b53d3a 189 SUPERFAMILY SSF75420 5 77 9.55E-18 T 26-04-2017 IPR028989 Ribosome maturation factor RimP, N-terminal A4V04_RS02710 d724651163a4e06b21f3238994b53d3a 189 Gene3D G3DSA:3.30.300.70 4 74 1.2E-17 T 26-04-2017 IPR028989 Ribosome maturation factor RimP, N-terminal A4V04_RS11590 792368e39edd5628cc9f16d0f99b3910 471 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 260 463 4.2E-27 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS11590 792368e39edd5628cc9f16d0f99b3910 471 SUPERFAMILY SSF161098 239 441 3.79E-19 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS11590 792368e39edd5628cc9f16d0f99b3910 471 Gene3D G3DSA:1.10.3720.10 236 461 2.3E-24 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS09005 b11dc9ba4696bff7644065d4701c5703 205 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 12 182 3.5E-34 T 26-04-2017 IPR010664 Lipopolysaccharide assembly, LptC-related A4V04_RS09005 b11dc9ba4696bff7644065d4701c5703 205 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 8 183 8.1E-40 T 26-04-2017 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 A4V04_RS06130 6d0289f59c25be43a21882f0869d9afb 340 Gene3D G3DSA:3.20.20.140 23 329 8.8E-78 T 26-04-2017 A4V04_RS06130 6d0289f59c25be43a21882f0869d9afb 340 ProDom PD049525 CYTOSINE HI0843 HYDROLASE RELATED METAL-DEPENDENT DEAMINASE HYDROLASES PM1882 287 328 3.0E-10 T 26-04-2017 A4V04_RS06130 6d0289f59c25be43a21882f0869d9afb 340 SUPERFAMILY SSF51556 22 329 1.99E-62 T 26-04-2017 IPR032466 Metal-dependent hydrolase A4V04_RS06130 6d0289f59c25be43a21882f0869d9afb 340 Pfam PF01979 Amidohydrolase family 22 329 4.6E-13 T 26-04-2017 IPR006680 Amidohydrolase-related GO:0016787 A4V04_RS01220 894030529283a68293e88e256f641691 46 Pfam PF13438 Domain of unknown function (DUF4113) 1 36 2.6E-7 T 26-04-2017 IPR025188 Domain of unknown function DUF4113 A4V04_RS01940 5c59d25e38d2ac09578193baf54bad86 759 SUPERFAMILY SSF53756 269 386 4.0E-5 T 26-04-2017 A4V04_RS01940 5c59d25e38d2ac09578193baf54bad86 759 Gene3D G3DSA:3.90.550.10 452 658 4.6E-39 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS01940 5c59d25e38d2ac09578193baf54bad86 759 Pfam PF00535 Glycosyl transferase family 2 457 630 1.8E-25 T 26-04-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4V04_RS01940 5c59d25e38d2ac09578193baf54bad86 759 SUPERFAMILY SSF53448 454 684 1.13E-38 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS00275 b3ad058258c0f82760a874f12e3057a0 208 SUPERFAMILY SSF48452 75 195 6.33E-10 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS00275 b3ad058258c0f82760a874f12e3057a0 208 Gene3D G3DSA:1.25.40.10 41 189 8.9E-8 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS00275 b3ad058258c0f82760a874f12e3057a0 208 Pfam PF09976 Tetratricopeptide repeat-like domain 15 208 3.6E-49 T 26-04-2017 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038 A4V04_RS00275 b3ad058258c0f82760a874f12e3057a0 208 PIRSF PIRSF006170 1 208 1.2E-48 T 26-04-2017 IPR026039 Uncharacterised protein family UPF0070 A4V04_RS06720 ef9ae32c0ccac82f719773141a45d09b 628 Gene3D G3DSA:3.40.630.30 535 565 7.2E-4 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS06720 ef9ae32c0ccac82f719773141a45d09b 628 Pfam PF12392 Collagenase 393 508 2.6E-20 T 26-04-2017 IPR020988 Peptidase U32, collagenase A4V04_RS06720 ef9ae32c0ccac82f719773141a45d09b 628 Pfam PF01136 Peptidase family U32 77 305 1.1E-66 T 26-04-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A4V04_RS08270 d5c399a56d71ab5bd3a5dce78fd245a5 493 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 465 4.4E-123 T 26-04-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 A4V04_RS08270 d5c399a56d71ab5bd3a5dce78fd245a5 493 Gene3D G3DSA:1.20.1600.10 142 314 1.8E-97 T 26-04-2017 A4V04_RS08270 d5c399a56d71ab5bd3a5dce78fd245a5 493 Gene3D G3DSA:1.20.1600.10 53 90 1.8E-97 T 26-04-2017 A4V04_RS08270 d5c399a56d71ab5bd3a5dce78fd245a5 493 Gene3D G3DSA:1.20.1600.10 352 465 1.8E-97 T 26-04-2017 A4V04_RS08270 d5c399a56d71ab5bd3a5dce78fd245a5 493 SUPERFAMILY SSF56954 2 465 4.19E-110 T 26-04-2017 A4V04_RS08270 d5c399a56d71ab5bd3a5dce78fd245a5 493 Gene3D G3DSA:2.20.200.10 100 141 4.6E-21 T 26-04-2017 A4V04_RS08270 d5c399a56d71ab5bd3a5dce78fd245a5 493 Gene3D G3DSA:2.20.200.10 315 350 4.6E-21 T 26-04-2017 A4V04_RS08270 d5c399a56d71ab5bd3a5dce78fd245a5 493 Pfam PF02321 Outer membrane efflux protein 283 463 5.5E-28 T 26-04-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A4V04_RS08270 d5c399a56d71ab5bd3a5dce78fd245a5 493 Pfam PF02321 Outer membrane efflux protein 65 254 1.2E-27 T 26-04-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A4V04_RS11340 3d0bdb61e06de84a03e3eb251e22809d 137 SUPERFAMILY SSF53137 23 137 3.01E-44 T 26-04-2017 A4V04_RS11340 3d0bdb61e06de84a03e3eb251e22809d 137 Gene3D G3DSA:3.30.420.80 14 137 5.4E-50 T 26-04-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A4V04_RS11340 3d0bdb61e06de84a03e3eb251e22809d 137 Pfam PF00411 Ribosomal protein S11 27 136 3.9E-48 T 26-04-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A4V04_RS11340 3d0bdb61e06de84a03e3eb251e22809d 137 PIRSF PIRSF002131 5 137 1.6E-49 T 26-04-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A4V04_RS11340 3d0bdb61e06de84a03e3eb251e22809d 137 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 18 134 2.0E-53 T 26-04-2017 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS11340 3d0bdb61e06de84a03e3eb251e22809d 137 ProSitePatterns PS00054 Ribosomal protein S11 signature. 105 127 - T 26-04-2017 IPR018102 Ribosomal S11, conserved site A4V04_RS11340 3d0bdb61e06de84a03e3eb251e22809d 137 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 137 30.723 T 26-04-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A4V04_RS09270 b7d137d21d00704269e6130047999c52 189 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 7 178 9.4E-40 T 26-04-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase A4V04_RS09270 b7d137d21d00704269e6130047999c52 189 Gene3D G3DSA:3.40.50.10420 7 180 2.2E-40 T 26-04-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain A4V04_RS09270 b7d137d21d00704269e6130047999c52 189 SUPERFAMILY SSF100950 6 182 1.14E-41 T 26-04-2017 A4V04_RS09270 b7d137d21d00704269e6130047999c52 189 PIRSF PIRSF006806 3 182 3.1E-34 T 26-04-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase A4V04_RS09270 b7d137d21d00704269e6130047999c52 189 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 7 178 4.1E-26 T 26-04-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase A4V04_RS08475 bdaadee7d7a16ad3b14749dcec5d0839 265 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 1 265 37.739 T 26-04-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A4V04_RS08475 bdaadee7d7a16ad3b14749dcec5d0839 265 Gene3D G3DSA:3.40.50.150 78 263 7.2E-59 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS08475 bdaadee7d7a16ad3b14749dcec5d0839 265 SUPERFAMILY SSF53335 17 246 1.49E-51 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS08475 bdaadee7d7a16ad3b14749dcec5d0839 265 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 172 178 - T 26-04-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4V04_RS08475 bdaadee7d7a16ad3b14749dcec5d0839 265 Pfam PF05175 Methyltransferase small domain 94 191 7.7E-20 T 26-04-2017 IPR007848 Methyltransferase small domain GO:0008168 A4V04_RS08475 bdaadee7d7a16ad3b14749dcec5d0839 265 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 26 262 7.0E-68 T 26-04-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 A4V04_RS08475 bdaadee7d7a16ad3b14749dcec5d0839 265 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 20 261 6.8E-83 T 26-04-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A4V04_RS08475 bdaadee7d7a16ad3b14749dcec5d0839 265 Gene3D G3DSA:1.10.8.10 15 77 8.7E-14 T 26-04-2017 A4V04_RS12725 36ed79ffd5cf94c95005602851a2d1ab 100 Pfam PF09820 Predicted AAA-ATPase 8 73 3.4E-19 T 26-04-2017 IPR018631 AAA-ATPase-like domain A4V04_RS05250 ebdccb7c36e56a218d46d0a2601d2e10 116 Gene3D G3DSA:1.20.120.160 40 115 7.7E-12 T 26-04-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A4V04_RS05250 ebdccb7c36e56a218d46d0a2601d2e10 116 SUPERFAMILY SSF47226 26 115 1.7E-13 T 26-04-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A4V04_RS05250 ebdccb7c36e56a218d46d0a2601d2e10 116 Pfam PF01627 Hpt domain 43 113 3.2E-5 T 26-04-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A4V04_RS04980 ab547253c476503508bfb833cbfc890a 469 PIRSF PIRSF002457 2 469 4.3E-142 T 26-04-2017 IPR030676 Citrate carrier CitT-related A4V04_RS04980 ab547253c476503508bfb833cbfc890a 469 Pfam PF00939 Sodium:sulfate symporter transmembrane region 9 467 9.5E-141 T 26-04-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A4V04_RS04980 ab547253c476503508bfb833cbfc890a 469 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 22 463 6.6E-122 T 26-04-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A4V04_RS01180 c271407ba4164fd7faf9484f74fba558 272 SUPERFAMILY SSF111331 2 264 9.03E-77 T 26-04-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain A4V04_RS01180 c271407ba4164fd7faf9484f74fba558 272 Gene3D G3DSA:3.40.50.10330 2 123 5.8E-30 T 26-04-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 A4V04_RS01180 c271407ba4164fd7faf9484f74fba558 272 Hamap MF_00361 NAD kinase [nadK]. 3 262 27.661 T 26-04-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 A4V04_RS01180 c271407ba4164fd7faf9484f74fba558 272 Gene3D G3DSA:2.60.200.30 124 236 1.0E-37 T 26-04-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 A4V04_RS01180 c271407ba4164fd7faf9484f74fba558 272 Pfam PF01513 ATP-NAD kinase 27 242 1.7E-48 T 26-04-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 A4V04_RS09530 1512006db1d7bacd6bafae57adb18cef 431 Pfam PF00860 Permease family 20 392 7.3E-46 T 26-04-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A4V04_RS09530 1512006db1d7bacd6bafae57adb18cef 431 PIRSF PIRSF005353 1 431 8.6E-169 T 26-04-2017 IPR026033 Purine permease PbuG-like A4V04_RS09330 514f126cf308a06bccc4380383cfa1a8 149 SUPERFAMILY SSF57716 109 147 3.14E-8 T 26-04-2017 A4V04_RS09330 514f126cf308a06bccc4380383cfa1a8 149 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 31 138 3.0E-42 T 26-04-2017 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 A4V04_RS09330 514f126cf308a06bccc4380383cfa1a8 149 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 107 141 4.8E-10 T 26-04-2017 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 A4V04_RS09330 514f126cf308a06bccc4380383cfa1a8 149 SUPERFAMILY SSF109635 16 108 2.75E-29 T 26-04-2017 A4V04_RS09330 514f126cf308a06bccc4380383cfa1a8 149 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 112 136 - T 26-04-2017 IPR020458 Zinc finger, DksA/TraR C4-type conserved site A4V04_RS09330 514f126cf308a06bccc4380383cfa1a8 149 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 27 148 26.975 T 26-04-2017 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 A4V04_RS12640 e6ffb36f7fa78625708c4c4ef38dbbd0 886 Pfam PF03552 Cellulose synthase 464 589 8.4E-9 T 26-04-2017 IPR005150 Cellulose synthase GO:0016020|GO:0016760|GO:0030244 A4V04_RS12640 e6ffb36f7fa78625708c4c4ef38dbbd0 886 SUPERFAMILY SSF53448 288 561 3.94E-49 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS12640 e6ffb36f7fa78625708c4c4ef38dbbd0 886 Gene3D G3DSA:3.90.550.10 286 519 4.8E-22 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS12640 e6ffb36f7fa78625708c4c4ef38dbbd0 886 Pfam PF00535 Glycosyl transferase family 2 289 460 1.8E-35 T 26-04-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4V04_RS12640 e6ffb36f7fa78625708c4c4ef38dbbd0 886 TIGRFAM TIGR03030 CelA: cellulose synthase catalytic subunit (UDP-forming) 161 842 2.6E-249 T 26-04-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 A4V04_RS12640 e6ffb36f7fa78625708c4c4ef38dbbd0 886 PRINTS PR01439 Cellulose synthase subunit A signature 566 585 4.0E-54 T 26-04-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 A4V04_RS12640 e6ffb36f7fa78625708c4c4ef38dbbd0 886 PRINTS PR01439 Cellulose synthase subunit A signature 240 265 4.0E-54 T 26-04-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 A4V04_RS12640 e6ffb36f7fa78625708c4c4ef38dbbd0 886 PRINTS PR01439 Cellulose synthase subunit A signature 606 625 4.0E-54 T 26-04-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 A4V04_RS12640 e6ffb36f7fa78625708c4c4ef38dbbd0 886 PRINTS PR01439 Cellulose synthase subunit A signature 537 563 4.0E-54 T 26-04-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 A4V04_RS12640 e6ffb36f7fa78625708c4c4ef38dbbd0 886 PRINTS PR01439 Cellulose synthase subunit A signature 680 701 4.0E-54 T 26-04-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 A4V04_RS12640 e6ffb36f7fa78625708c4c4ef38dbbd0 886 PRINTS PR01439 Cellulose synthase subunit A signature 376 400 4.0E-54 T 26-04-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 A4V04_RS12640 e6ffb36f7fa78625708c4c4ef38dbbd0 886 PRINTS PR01439 Cellulose synthase subunit A signature 212 232 4.0E-54 T 26-04-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 A4V04_RS12640 e6ffb36f7fa78625708c4c4ef38dbbd0 886 PRINTS PR01439 Cellulose synthase subunit A signature 295 314 4.0E-54 T 26-04-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 A4V04_RS12325 a1c4ae15b1d1cf431173a14d0b3bb22b 217 SUPERFAMILY SSF49777 5 210 5.89E-37 T 26-04-2017 IPR008914 Phosphatidylethanolamine-binding protein A4V04_RS12325 a1c4ae15b1d1cf431173a14d0b3bb22b 217 Gene3D G3DSA:3.90.280.10 5 213 2.2E-52 T 26-04-2017 IPR008914 Phosphatidylethanolamine-binding protein A4V04_RS12325 a1c4ae15b1d1cf431173a14d0b3bb22b 217 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 82 207 8.3E-18 T 26-04-2017 IPR005247 YbhB/YbcL A4V04_RS12325 a1c4ae15b1d1cf431173a14d0b3bb22b 217 Pfam PF01161 Phosphatidylethanolamine-binding protein 38 207 5.3E-33 T 26-04-2017 IPR008914 Phosphatidylethanolamine-binding protein A4V04_RS06560 912caec2f621e7c51991be891ddeca8e 106 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 91 3.7E-10 T 26-04-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4V04_RS01005 b0f16fe5867a0989ab7c8c6153fe11b1 164 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 24 142 5.7E-15 T 26-04-2017 IPR007621 TPM domain A4V04_RS12800 ee530e841f264a48a83a0ac9b610ef1f 388 Gene3D G3DSA:1.20.1250.20 205 379 1.3E-12 T 26-04-2017 A4V04_RS12800 ee530e841f264a48a83a0ac9b610ef1f 388 Gene3D G3DSA:1.20.1250.20 9 197 3.4E-18 T 26-04-2017 A4V04_RS12800 ee530e841f264a48a83a0ac9b610ef1f 388 SUPERFAMILY SSF103473 7 379 1.44E-32 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS12800 ee530e841f264a48a83a0ac9b610ef1f 388 Pfam PF07690 Major Facilitator Superfamily 14 332 7.3E-16 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS12490 66fd4a215934e4064ad7624a06bc5f40 494 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 64 1.0E-6 T 26-04-2017 A4V04_RS12490 66fd4a215934e4064ad7624a06bc5f40 494 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 451 466 1.0E-6 T 26-04-2017 A4V04_RS12490 66fd4a215934e4064ad7624a06bc5f40 494 Gene3D G3DSA:3.90.700.10 301 424 5.1E-20 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS12490 66fd4a215934e4064ad7624a06bc5f40 494 SUPERFAMILY SSF51905 28 257 1.3E-39 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12490 66fd4a215934e4064ad7624a06bc5f40 494 SUPERFAMILY SSF51905 434 491 1.3E-39 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12490 66fd4a215934e4064ad7624a06bc5f40 494 SUPERFAMILY SSF56425 301 434 1.43E-19 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS12490 66fd4a215934e4064ad7624a06bc5f40 494 Pfam PF00890 FAD binding domain 42 467 1.2E-47 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS12490 66fd4a215934e4064ad7624a06bc5f40 494 Gene3D G3DSA:3.50.50.60 30 279 3.4E-68 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12490 66fd4a215934e4064ad7624a06bc5f40 494 Gene3D G3DSA:3.50.50.60 431 490 3.4E-68 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS00180 c7d879082a9abd6707079003a82efaae 118 SUPERFAMILY SSF74731 2 116 9.03E-47 T 26-04-2017 A4V04_RS00180 c7d879082a9abd6707079003a82efaae 118 Pfam PF00453 Ribosomal protein L20 3 109 1.1E-46 T 26-04-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00180 c7d879082a9abd6707079003a82efaae 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 26-04-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00180 c7d879082a9abd6707079003a82efaae 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 2.3E-47 T 26-04-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00180 c7d879082a9abd6707079003a82efaae 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.785 T 26-04-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00180 c7d879082a9abd6707079003a82efaae 118 Gene3D G3DSA:1.10.1900.20 55 117 2.9E-30 T 26-04-2017 A4V04_RS00180 c7d879082a9abd6707079003a82efaae 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 72 7.0E-11 T 26-04-2017 A4V04_RS00180 c7d879082a9abd6707079003a82efaae 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.7E-36 T 26-04-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00180 c7d879082a9abd6707079003a82efaae 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.7E-36 T 26-04-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS00180 c7d879082a9abd6707079003a82efaae 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.7E-36 T 26-04-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS06390 993faa4dbd0dee03e64f3443ed2931c6 1053 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 21 2.6E-10 T 26-04-2017 IPR024973 ESPR domain A4V04_RS07890 9e11adc837886aad1919325e2ff063a8 267 Pfam PF12679 ABC-2 family transporter protein 7 255 8.4E-24 T 26-04-2017 IPR032688 ABC-2 family transporter protein GO:0006810 A4V04_RS07680 591b049fb08cea126071f1efd545fad2 390 SUPERFAMILY SSF53254 34 343 2.29E-34 T 26-04-2017 IPR029033 Histidine phosphatase superfamily A4V04_RS07680 591b049fb08cea126071f1efd545fad2 390 Pfam PF00328 Histidine phosphatase superfamily (branch 2) 35 171 6.2E-10 T 26-04-2017 IPR000560 Histidine phosphatase superfamily, clade-2 GO:0003993 A4V04_RS07680 591b049fb08cea126071f1efd545fad2 390 Gene3D G3DSA:3.40.50.1240 141 250 2.4E-6 T 26-04-2017 IPR029033 Histidine phosphatase superfamily A4V04_RS07680 591b049fb08cea126071f1efd545fad2 390 ProSitePatterns PS00616 Histidine acid phosphatases phosphohistidine signature. 36 50 - T 26-04-2017 IPR033379 Histidine acid phosphatase active site A4V04_RS07680 591b049fb08cea126071f1efd545fad2 390 Gene3D G3DSA:3.40.50.1240 35 140 1.1E-38 T 26-04-2017 IPR029033 Histidine phosphatase superfamily A4V04_RS07680 591b049fb08cea126071f1efd545fad2 390 Gene3D G3DSA:3.40.50.1240 261 366 1.1E-38 T 26-04-2017 IPR029033 Histidine phosphatase superfamily A4V04_RS10400 3da1c8712781cfd7f0bc5c1efde0a03b 389 SMART SM00936 279 374 7.4E-9 T 26-04-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4V04_RS10400 3da1c8712781cfd7f0bc5c1efde0a03b 389 SUPERFAMILY SSF69189 279 372 9.02E-11 T 26-04-2017 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4V04_RS10400 3da1c8712781cfd7f0bc5c1efde0a03b 389 Gene3D G3DSA:2.60.410.10 279 372 9.4E-13 T 26-04-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4V04_RS10400 3da1c8712781cfd7f0bc5c1efde0a03b 389 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 279 372 1.5E-11 T 26-04-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4V04_RS04430 ee4c1a2706d789118389537c66d6eb6b 138 PIRSF PIRSF006019 1 138 4.0E-39 T 26-04-2017 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-500753 A4V04_RS04430 ee4c1a2706d789118389537c66d6eb6b 138 SUPERFAMILY SSF53927 9 137 5.19E-35 T 26-04-2017 IPR016193 Cytidine deaminase-like GO:0003824 A4V04_RS04430 ee4c1a2706d789118389537c66d6eb6b 138 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 7 116 3.2E-27 T 26-04-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 A4V04_RS04430 ee4c1a2706d789118389537c66d6eb6b 138 Gene3D G3DSA:3.40.140.10 8 138 7.2E-36 T 26-04-2017 A4V04_RS04430 ee4c1a2706d789118389537c66d6eb6b 138 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 105 - T 26-04-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A4V04_RS12680 23e45aad510f8a66920358158989f302 118 Pfam PF05717 IS66 Orf2 like protein 10 109 6.7E-16 T 26-04-2017 IPR008878 Transposase IS66, Orf2 A4V04_RS04190 23e45aad510f8a66920358158989f302 118 Pfam PF05717 IS66 Orf2 like protein 10 109 6.7E-16 T 26-04-2017 IPR008878 Transposase IS66, Orf2 A4V04_RS05715 23e45aad510f8a66920358158989f302 118 Pfam PF05717 IS66 Orf2 like protein 10 109 6.7E-16 T 26-04-2017 IPR008878 Transposase IS66, Orf2 A4V04_RS11190 23e45aad510f8a66920358158989f302 118 Pfam PF05717 IS66 Orf2 like protein 10 109 6.7E-16 T 26-04-2017 IPR008878 Transposase IS66, Orf2 A4V04_RS02860 23e45aad510f8a66920358158989f302 118 Pfam PF05717 IS66 Orf2 like protein 10 109 6.7E-16 T 26-04-2017 IPR008878 Transposase IS66, Orf2 A4V04_RS04140 23e45aad510f8a66920358158989f302 118 Pfam PF05717 IS66 Orf2 like protein 10 109 6.7E-16 T 26-04-2017 IPR008878 Transposase IS66, Orf2 A4V04_RS01655 95bc78d38a0deb9a7f8afe4b04842a28 440 PRINTS PR00149 Fumarate lyase superfamily signature 94 112 3.7E-23 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01655 95bc78d38a0deb9a7f8afe4b04842a28 440 PRINTS PR00149 Fumarate lyase superfamily signature 239 266 3.7E-23 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01655 95bc78d38a0deb9a7f8afe4b04842a28 440 PRINTS PR00149 Fumarate lyase superfamily signature 285 301 3.7E-23 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01655 95bc78d38a0deb9a7f8afe4b04842a28 440 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 3.7E-23 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01655 95bc78d38a0deb9a7f8afe4b04842a28 440 Gene3D G3DSA:1.10.275.10 9 83 9.3E-8 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS01655 95bc78d38a0deb9a7f8afe4b04842a28 440 SUPERFAMILY SSF48557 9 408 2.67E-57 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS01655 95bc78d38a0deb9a7f8afe4b04842a28 440 Gene3D G3DSA:1.20.200.10 101 365 2.7E-47 T 26-04-2017 A4V04_RS01655 95bc78d38a0deb9a7f8afe4b04842a28 440 Pfam PF00206 Lyase 8 307 6.7E-44 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS01655 95bc78d38a0deb9a7f8afe4b04842a28 440 ProSitePatterns PS00163 Fumarate lyases signature. 285 294 - T 26-04-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 A4V04_RS03745 16a33804507a7d11d1435d1c6b329175 249 SUPERFAMILY SSF53448 1 96 2.53E-20 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS03745 16a33804507a7d11d1435d1c6b329175 249 Gene3D G3DSA:3.90.550.10 1 91 3.8E-14 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS03745 16a33804507a7d11d1435d1c6b329175 249 Pfam PF00535 Glycosyl transferase family 2 2 137 1.1E-17 T 26-04-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4V04_RS08260 dcf87034b37dafdee0743a26fb073fed 353 PIRSF PIRSF001361 1 351 6.1E-159 T 26-04-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4V04_RS08260 dcf87034b37dafdee0743a26fb073fed 353 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 349 7.7E-165 T 26-04-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4V04_RS08260 dcf87034b37dafdee0743a26fb073fed 353 Gene3D G3DSA:3.20.20.70 9 349 4.2E-153 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS08260 dcf87034b37dafdee0743a26fb073fed 353 Pfam PF00793 DAHP synthetase I family 39 336 4.1E-103 T 26-04-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A4V04_RS08260 dcf87034b37dafdee0743a26fb073fed 353 SUPERFAMILY SSF51569 7 348 7.88E-136 T 26-04-2017 A4V04_RS01810 ef00417f87fb9620ef069894af629d87 213 Pfam PF09676 Type IV conjugative transfer system lipoprotein (TraV) 30 168 1.3E-16 T 26-04-2017 IPR014118 Type IV conjugative transfer system protein TraV A4V04_RS01810 ef00417f87fb9620ef069894af629d87 213 TIGRFAM TIGR02747 TraV: type IV conjugative transfer system protein TraV 4 168 8.8E-19 T 26-04-2017 IPR014118 Type IV conjugative transfer system protein TraV A4V04_RS07370 f5f69d46532f04c11f32842ed3bd5a37 615 Pfam PF02386 Cation transport protein 164 596 1.1E-44 T 26-04-2017 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A4V04_RS06370 d5baf41f8009874c96b20508c9fbd2c9 111 SUPERFAMILY SSF143011 1 93 7.85E-7 T 26-04-2017 A4V04_RS06370 d5baf41f8009874c96b20508c9fbd2c9 111 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 98 8.2E-15 T 26-04-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4V04_RS09140 b7b139a8b4ca8d7a1d154c2cd3ae3fde 339 Pfam PF04909 Amidohydrolase 136 338 6.2E-22 T 26-04-2017 IPR006680 Amidohydrolase-related GO:0016787 A4V04_RS09140 b7b139a8b4ca8d7a1d154c2cd3ae3fde 339 SUPERFAMILY SSF51556 102 339 1.1E-33 T 26-04-2017 IPR032466 Metal-dependent hydrolase A4V04_RS09140 b7b139a8b4ca8d7a1d154c2cd3ae3fde 339 Gene3D G3DSA:3.20.20.140 92 339 4.2E-40 T 26-04-2017 A4V04_RS03390 76b552a28cd419c5a509200632046c52 240 SUPERFAMILY SSF56672 3 174 1.19E-23 T 26-04-2017 A4V04_RS03390 76b552a28cd419c5a509200632046c52 240 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 7 98 8.4E-19 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS03390 76b552a28cd419c5a509200632046c52 240 Pfam PF08388 Group II intron, maturase-specific domain 113 186 1.0E-13 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS00525 05792c093311aab17b1da3394d9a632c 142 Pfam PF13262 Protein of unknown function (DUF4054) 11 123 3.6E-17 T 26-04-2017 IPR025127 Protein of unknown function DUF4054 A4V04_RS08550 5c5e9ffd140674a991c7dd74c45aaa90 494 SUPERFAMILY SSF48452 291 348 8.16E-10 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS08550 5c5e9ffd140674a991c7dd74c45aaa90 494 SUPERFAMILY SSF48452 386 468 8.16E-10 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS08550 5c5e9ffd140674a991c7dd74c45aaa90 494 Gene3D G3DSA:1.25.40.10 293 464 2.2E-11 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS08550 5c5e9ffd140674a991c7dd74c45aaa90 494 Gene3D G3DSA:3.30.2010.10 65 147 3.2E-20 T 26-04-2017 A4V04_RS08550 5c5e9ffd140674a991c7dd74c45aaa90 494 Pfam PF01435 Peptidase family M48 71 260 9.8E-32 T 26-04-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4V04_RS03130 1eaa7765d8def6eacf82010db6f3dd6f 400 SUPERFAMILY SSF53383 9 396 8.76E-101 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS03130 1eaa7765d8def6eacf82010db6f3dd6f 400 Gene3D G3DSA:3.90.1150.10 274 396 2.0E-14 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS03130 1eaa7765d8def6eacf82010db6f3dd6f 400 Gene3D G3DSA:3.40.640.10 62 273 1.5E-71 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS03130 1eaa7765d8def6eacf82010db6f3dd6f 400 Pfam PF00155 Aminotransferase class I and II 49 389 1.2E-35 T 26-04-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4V04_RS11680 1c89ed7e7d59c35c36af5885513d5063 429 Gene3D G3DSA:2.40.30.10 218 299 2.4E-16 T 26-04-2017 A4V04_RS11680 1c89ed7e7d59c35c36af5885513d5063 429 Gene3D G3DSA:3.40.50.80 300 370 1.7E-8 T 26-04-2017 A4V04_RS11680 1c89ed7e7d59c35c36af5885513d5063 429 SUPERFAMILY SSF63380 219 308 2.69E-17 T 26-04-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A4V04_RS11680 1c89ed7e7d59c35c36af5885513d5063 429 SUPERFAMILY SSF52343 297 370 7.33E-11 T 26-04-2017 A4V04_RS11680 1c89ed7e7d59c35c36af5885513d5063 429 Pfam PF01794 Ferric reductase like transmembrane component 39 174 1.1E-14 T 26-04-2017 IPR013130 Ferric reductase transmembrane component-like domain A4V04_RS11680 1c89ed7e7d59c35c36af5885513d5063 429 Pfam PF08022 FAD-binding domain 223 295 1.2E-6 T 26-04-2017 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 A4V04_RS02355 2970610631a9b59d867f5a916009412b 470 Gene3D G3DSA:3.50.50.60 408 468 1.3E-81 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02355 2970610631a9b59d867f5a916009412b 470 Gene3D G3DSA:3.50.50.60 28 265 1.3E-81 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02355 2970610631a9b59d867f5a916009412b 470 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 34 464 8.4E-104 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS02355 2970610631a9b59d867f5a916009412b 470 SUPERFAMILY SSF51905 28 282 1.18E-48 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02355 2970610631a9b59d867f5a916009412b 470 SUPERFAMILY SSF51905 411 468 1.18E-48 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02355 2970610631a9b59d867f5a916009412b 470 Pfam PF00890 FAD binding domain 34 452 3.8E-67 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02355 2970610631a9b59d867f5a916009412b 470 SUPERFAMILY SSF56425 275 412 1.74E-24 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02355 2970610631a9b59d867f5a916009412b 470 Gene3D G3DSA:3.90.700.10 289 401 2.6E-21 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS01450 ad7d65d0a233da8b8dbc451132412822 1811 Pfam PF05359 Domain of Unknown Function (DUF748) 146 301 4.7E-12 T 26-04-2017 IPR008023 Protein of unknown function DUF748 A4V04_RS01450 ad7d65d0a233da8b8dbc451132412822 1811 Pfam PF05359 Domain of Unknown Function (DUF748) 996 1144 5.5E-22 T 26-04-2017 IPR008023 Protein of unknown function DUF748 A4V04_RS01450 ad7d65d0a233da8b8dbc451132412822 1811 Pfam PF05359 Domain of Unknown Function (DUF748) 1211 1357 7.4E-24 T 26-04-2017 IPR008023 Protein of unknown function DUF748 A4V04_RS01450 ad7d65d0a233da8b8dbc451132412822 1811 Pfam PF05359 Domain of Unknown Function (DUF748) 1432 1570 1.1E-24 T 26-04-2017 IPR008023 Protein of unknown function DUF748 A4V04_RS01450 ad7d65d0a233da8b8dbc451132412822 1811 Pfam PF00691 OmpA family 1763 1792 1.3E-4 T 26-04-2017 IPR006665 OmpA-like domain A4V04_RS01450 ad7d65d0a233da8b8dbc451132412822 1811 Gene3D G3DSA:3.30.1330.60 1642 1686 5.7E-9 T 26-04-2017 IPR006665 OmpA-like domain A4V04_RS01450 ad7d65d0a233da8b8dbc451132412822 1811 Gene3D G3DSA:3.30.1330.60 1758 1791 5.7E-9 T 26-04-2017 IPR006665 OmpA-like domain A4V04_RS04115 b99a1d7acfa88d6bfae2e955d12f4162 436 SUPERFAMILY SSF56935 89 436 1.62E-49 T 26-04-2017 A4V04_RS04115 b99a1d7acfa88d6bfae2e955d12f4162 436 Pfam PF13609 Gram-negative porin 75 413 3.7E-39 T 26-04-2017 A4V04_RS04115 b99a1d7acfa88d6bfae2e955d12f4162 436 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 222 233 4.2E-5 T 26-04-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 A4V04_RS04115 b99a1d7acfa88d6bfae2e955d12f4162 436 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 161 171 4.2E-5 T 26-04-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 A4V04_RS04115 b99a1d7acfa88d6bfae2e955d12f4162 436 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 253 265 4.2E-5 T 26-04-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 A4V04_RS04115 b99a1d7acfa88d6bfae2e955d12f4162 436 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 391 408 4.2E-5 T 26-04-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 A4V04_RS04115 b99a1d7acfa88d6bfae2e955d12f4162 436 Gene3D G3DSA:2.40.160.10 89 424 4.5E-62 T 26-04-2017 IPR023614 Porin domain A4V04_RS11275 82220fab058e7ed78335a9a1df9f971d 122 Gene3D G3DSA:2.40.150.20 1 122 1.2E-53 T 26-04-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4V04_RS11275 82220fab058e7ed78335a9a1df9f971d 122 SUPERFAMILY SSF50193 1 122 4.32E-50 T 26-04-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4V04_RS11275 82220fab058e7ed78335a9a1df9f971d 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 26-04-2017 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11275 82220fab058e7ed78335a9a1df9f971d 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.985 T 26-04-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4V04_RS11275 82220fab058e7ed78335a9a1df9f971d 122 SMART SM01374 1 122 1.8E-82 T 26-04-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4V04_RS11275 82220fab058e7ed78335a9a1df9f971d 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 6.1E-57 T 26-04-2017 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 A4V04_RS11275 82220fab058e7ed78335a9a1df9f971d 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 1.4E-53 T 26-04-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4V04_RS01890 77a3a712fbfa6f1a3399580c8b920107 327 SMART SM00778 38 74 5.3E-11 T 26-04-2017 IPR013237 Bacteriophage T7, Gp4, DNA primase/helicase, N-terminal GO:0003896|GO:0004386|GO:0008270 A4V04_RS01890 77a3a712fbfa6f1a3399580c8b920107 327 SUPERFAMILY SSF57783 40 101 4.85E-8 T 26-04-2017 A4V04_RS01890 77a3a712fbfa6f1a3399580c8b920107 327 Pfam PF13362 Toprim domain 233 324 6.3E-13 T 26-04-2017 IPR006171 Toprim domain A4V04_RS01890 77a3a712fbfa6f1a3399580c8b920107 327 Pfam PF08273 Zinc-binding domain of primase-helicase 41 73 7.6E-11 T 26-04-2017 IPR013237 Bacteriophage T7, Gp4, DNA primase/helicase, N-terminal GO:0003896|GO:0004386|GO:0008270 A4V04_RS01890 77a3a712fbfa6f1a3399580c8b920107 327 Gene3D G3DSA:3.90.580.10 41 101 1.4E-6 T 26-04-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A4V04_RS11880 a2efff16ac7877eb09efe97a8583d544 129 Pfam PF02472 Biopolymer transport protein ExbD/TolR 7 124 2.8E-20 T 26-04-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 A4V04_RS11845 6dd5583d6e2143d07bb2c1126c12cf35 713 Pfam PF07715 TonB-dependent Receptor Plug Domain 45 149 4.0E-28 T 26-04-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 A4V04_RS11845 6dd5583d6e2143d07bb2c1126c12cf35 713 SUPERFAMILY SSF56935 23 713 5.49E-109 T 26-04-2017 A4V04_RS11845 6dd5583d6e2143d07bb2c1126c12cf35 713 Pfam PF00593 TonB dependent receptor 469 711 4.7E-32 T 26-04-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A4V04_RS11845 6dd5583d6e2143d07bb2c1126c12cf35 713 Gene3D G3DSA:2.40.170.20 460 712 8.7E-78 T 26-04-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A4V04_RS11845 6dd5583d6e2143d07bb2c1126c12cf35 713 Gene3D G3DSA:2.40.170.20 153 423 8.7E-78 T 26-04-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A4V04_RS11845 6dd5583d6e2143d07bb2c1126c12cf35 713 Gene3D G3DSA:2.170.130.10 23 152 4.5E-40 T 26-04-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 A4V04_RS02270 0665e64b3d0d131c0c251c0fdd513f0e 313 Pfam PF00892 EamA-like transporter family 3 108 1.2E-11 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS02270 0665e64b3d0d131c0c251c0fdd513f0e 313 SUPERFAMILY SSF103481 37 108 4.58E-5 T 26-04-2017 A4V04_RS02930 94210d27030eb9f68cb3d9e6656ad341 133 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 131 7.1E-29 T 26-04-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A4V04_RS02930 94210d27030eb9f68cb3d9e6656ad341 133 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 103 4.0E-16 T 26-04-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A4V04_RS02930 94210d27030eb9f68cb3d9e6656ad341 133 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 129 23.43 T 26-04-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A4V04_RS02930 94210d27030eb9f68cb3d9e6656ad341 133 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 106 2.0E-19 T 26-04-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4V04_RS02930 94210d27030eb9f68cb3d9e6656ad341 133 Gene3D G3DSA:3.90.470.20 2 128 1.8E-32 T 26-04-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4V04_RS02930 94210d27030eb9f68cb3d9e6656ad341 133 SUPERFAMILY SSF56214 2 128 5.62E-26 T 26-04-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4V04_RS02930 94210d27030eb9f68cb3d9e6656ad341 133 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 129 6.7E-25 T 26-04-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 Gene3D G3DSA:1.20.200.10 112 380 5.7E-63 T 26-04-2017 A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 468 29.226 T 26-04-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 Gene3D G3DSA:1.10.40.30 381 442 2.6E-13 T 26-04-2017 A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 Gene3D G3DSA:1.10.275.10 35 111 1.8E-11 T 26-04-2017 IPR024083 Fumarase/histidase, N-terminal A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 PRINTS PR00149 Fumarate lyase superfamily signature 236 263 9.1E-20 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 9.1E-20 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 PRINTS PR00149 Fumarate lyase superfamily signature 107 125 9.1E-20 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 PRINTS PR00149 Fumarate lyase superfamily signature 152 170 9.1E-20 T 26-04-2017 IPR000362 Fumarate lyase family A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 Pfam PF00206 Lyase 49 302 2.5E-41 T 26-04-2017 IPR022761 Fumarate lyase, N-terminal A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 TIGRFAM TIGR00838 argH: argininosuccinate lyase 7 470 6.9E-111 T 26-04-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 Pfam PF14698 Argininosuccinate lyase C-terminal 369 442 1.6E-14 T 26-04-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 PRINTS PR00145 Argininosuccinate lyase family signature 106 128 1.0E-26 T 26-04-2017 A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 PRINTS PR00145 Argininosuccinate lyase family signature 280 296 1.0E-26 T 26-04-2017 A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 PRINTS PR00145 Argininosuccinate lyase family signature 147 167 1.0E-26 T 26-04-2017 A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 PRINTS PR00145 Argininosuccinate lyase family signature 236 260 1.0E-26 T 26-04-2017 A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 PRINTS PR00145 Argininosuccinate lyase family signature 198 214 1.0E-26 T 26-04-2017 A4V04_RS01530 8c107a6440bfaa7c8176c76b010eb749 502 SUPERFAMILY SSF48557 32 470 1.73E-92 T 26-04-2017 IPR008948 L-Aspartase-like GO:0003824 A4V04_RS02030 fcfd47221a0a42a47e69a0bff1704ce0 685 Pfam PF03050 Transposase IS66 family 270 597 2.6E-29 T 26-04-2017 IPR004291 Transposase, IS66 A4V04_RS06765 bdbf2e50b66bbcec08020a94c762b2e9 62 Pfam PF04995 Heme exporter protein D (CcmD) 14 55 6.1E-11 T 26-04-2017 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 A4V04_RS06765 bdbf2e50b66bbcec08020a94c762b2e9 62 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 12 54 2.5E-12 T 26-04-2017 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 A4V04_RS13100 287dee5b14167e78513bcd3c389db1de 642 Pfam PF13604 AAA domain 158 357 1.6E-29 T 26-04-2017 A4V04_RS13100 287dee5b14167e78513bcd3c389db1de 642 Gene3D G3DSA:3.40.50.300 139 355 6.2E-41 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13100 287dee5b14167e78513bcd3c389db1de 642 Pfam PF13538 UvrD-like helicase C-terminal domain 542 597 3.8E-10 T 26-04-2017 IPR027785 UvrD-like helicase C-terminal domain A4V04_RS13100 287dee5b14167e78513bcd3c389db1de 642 SUPERFAMILY SSF52540 444 622 1.33E-37 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13100 287dee5b14167e78513bcd3c389db1de 642 SUPERFAMILY SSF52540 289 355 1.33E-37 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13100 287dee5b14167e78513bcd3c389db1de 642 Gene3D G3DSA:3.40.50.300 544 602 7.3E-9 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS13100 287dee5b14167e78513bcd3c389db1de 642 SUPERFAMILY SSF52540 107 329 1.78E-28 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05190 b39d48f7d4ff831ed1893d71fcfefc2e 82 Pfam PF09012 FeoC like transcriptional regulator 2 70 9.7E-19 T 26-04-2017 IPR015102 Transcriptional regulator HTH-type, FeoC A4V04_RS05190 b39d48f7d4ff831ed1893d71fcfefc2e 82 SUPERFAMILY SSF46785 1 73 1.98E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS05190 b39d48f7d4ff831ed1893d71fcfefc2e 82 Gene3D G3DSA:1.10.10.10 9 48 6.3E-5 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09950 79fca3438f77f470ccedae7437b18ab2 490 Pfam PF02386 Cation transport protein 45 484 4.4E-57 T 26-04-2017 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A4V04_RS09950 79fca3438f77f470ccedae7437b18ab2 490 PIRSF PIRSF006247 6 490 2.7E-144 T 26-04-2017 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 A4V04_RS12145 abd203ed760ff44f2f691f48c3e4f2e9 320 PIRSF PIRSF036298 43 320 1.1E-61 T 26-04-2017 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 A4V04_RS12145 abd203ed760ff44f2f691f48c3e4f2e9 320 Gene3D G3DSA:3.30.70.20 219 266 1.7E-28 T 26-04-2017 A4V04_RS12145 abd203ed760ff44f2f691f48c3e4f2e9 320 Gene3D G3DSA:3.30.70.20 56 150 1.7E-28 T 26-04-2017 A4V04_RS12145 abd203ed760ff44f2f691f48c3e4f2e9 320 Gene3D G3DSA:3.30.70.20 151 184 5.2E-14 T 26-04-2017 A4V04_RS12145 abd203ed760ff44f2f691f48c3e4f2e9 320 Gene3D G3DSA:3.30.70.20 185 218 1.5E-14 T 26-04-2017 A4V04_RS12145 abd203ed760ff44f2f691f48c3e4f2e9 320 Pfam PF13247 4Fe-4S dicluster domain 139 234 8.9E-25 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS12145 abd203ed760ff44f2f691f48c3e4f2e9 320 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 179 190 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS12145 abd203ed760ff44f2f691f48c3e4f2e9 320 SUPERFAMILY SSF54862 55 294 2.3E-56 T 26-04-2017 A4V04_RS12145 abd203ed760ff44f2f691f48c3e4f2e9 320 Pfam PF12800 4Fe-4S binding domain 66 78 0.031 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS02300 f7e0142318efa6c3468267c42d66db14 552 Gene3D G3DSA:3.90.700.10 324 488 8.3E-23 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02300 f7e0142318efa6c3468267c42d66db14 552 SUPERFAMILY SSF56425 326 499 1.4E-17 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02300 f7e0142318efa6c3468267c42d66db14 552 SUPERFAMILY SSF51905 498 551 3.57E-38 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02300 f7e0142318efa6c3468267c42d66db14 552 SUPERFAMILY SSF51905 200 319 3.57E-38 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02300 f7e0142318efa6c3468267c42d66db14 552 SUPERFAMILY SSF51905 23 168 3.57E-38 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02300 f7e0142318efa6c3468267c42d66db14 552 Pfam PF00890 FAD binding domain 36 528 9.1E-54 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02300 f7e0142318efa6c3468267c42d66db14 552 Gene3D G3DSA:3.50.50.60 26 302 4.3E-64 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02300 f7e0142318efa6c3468267c42d66db14 552 Gene3D G3DSA:3.50.50.60 495 551 4.3E-64 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04640 b140fbe47e361409fa51b5ab7b3b6ed6 393 SUPERFAMILY SSF53774 34 363 1.57E-85 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS04640 b140fbe47e361409fa51b5ab7b3b6ed6 393 PRINTS PR00139 Asparaginase/glutaminase family signature 41 52 1.3E-18 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS04640 b140fbe47e361409fa51b5ab7b3b6ed6 393 PRINTS PR00139 Asparaginase/glutaminase family signature 301 319 1.3E-18 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS04640 b140fbe47e361409fa51b5ab7b3b6ed6 393 PRINTS PR00139 Asparaginase/glutaminase family signature 117 135 1.3E-18 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS04640 b140fbe47e361409fa51b5ab7b3b6ed6 393 PIRSF PIRSF001220 35 372 1.2E-81 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS04640 b140fbe47e361409fa51b5ab7b3b6ed6 393 PIRSF PIRSF500176 37 369 4.8E-77 T 26-04-2017 A4V04_RS04640 b140fbe47e361409fa51b5ab7b3b6ed6 393 SMART SM00870 40 366 7.8E-104 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS04640 b140fbe47e361409fa51b5ab7b3b6ed6 393 Gene3D G3DSA:3.40.50.1170 37 235 4.4E-59 T 26-04-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A4V04_RS04640 b140fbe47e361409fa51b5ab7b3b6ed6 393 Pfam PF00710 Asparaginase, N-terminal 41 230 2.5E-54 T 26-04-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A4V04_RS04640 b140fbe47e361409fa51b5ab7b3b6ed6 393 Gene3D G3DSA:3.40.50.40 254 362 1.4E-23 T 26-04-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 A4V04_RS04640 b140fbe47e361409fa51b5ab7b3b6ed6 393 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 118 128 - T 26-04-2017 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A4V04_RS00750 52ebf2990c14bdecbcd88dc4c9484c16 549 Pfam PF13751 Transposase DDE domain 387 491 1.7E-21 T 26-04-2017 IPR025668 Transposase DDE domain A4V04_RS00750 52ebf2990c14bdecbcd88dc4c9484c16 549 Pfam PF05598 Transposase domain (DUF772) 51 119 2.3E-7 T 26-04-2017 IPR008490 Transposase InsH, N-terminal A4V04_RS07270 52ebf2990c14bdecbcd88dc4c9484c16 549 Pfam PF13751 Transposase DDE domain 387 491 1.7E-21 T 26-04-2017 IPR025668 Transposase DDE domain A4V04_RS07270 52ebf2990c14bdecbcd88dc4c9484c16 549 Pfam PF05598 Transposase domain (DUF772) 51 119 2.3E-7 T 26-04-2017 IPR008490 Transposase InsH, N-terminal A4V04_RS04535 15889645821138f7b0a743ce34605205 316 Pfam PF01207 Dihydrouridine synthase (Dus) 1 256 8.2E-31 T 26-04-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4V04_RS04535 15889645821138f7b0a743ce34605205 316 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 81 99 - T 26-04-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4V04_RS04535 15889645821138f7b0a743ce34605205 316 Gene3D G3DSA:3.20.20.70 1 231 8.0E-40 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS04535 15889645821138f7b0a743ce34605205 316 SUPERFAMILY SSF51395 1 301 1.44E-35 T 26-04-2017 A4V04_RS04535 15889645821138f7b0a743ce34605205 316 PIRSF PIRSF006621 1 309 1.8E-46 T 26-04-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4V04_RS07350 27095da4c2259259cffc2cf145297f46 332 SUPERFAMILY SSF46689 277 328 4.48E-10 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS07350 27095da4c2259259cffc2cf145297f46 332 Pfam PF12833 Helix-turn-helix domain 247 327 2.4E-16 T 26-04-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4V04_RS07350 27095da4c2259259cffc2cf145297f46 332 SMART SM00342 241 326 2.4E-18 T 26-04-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4V04_RS07350 27095da4c2259259cffc2cf145297f46 332 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 310 326 1.2E-6 T 26-04-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4V04_RS07350 27095da4c2259259cffc2cf145297f46 332 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 295 310 1.2E-6 T 26-04-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4V04_RS07350 27095da4c2259259cffc2cf145297f46 332 Gene3D G3DSA:1.10.10.60 277 328 3.0E-13 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS11440 2b66433f1688c4523297f6804f4cc71e 632 Gene3D G3DSA:3.90.700.10 442 567 2.6E-29 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11440 2b66433f1688c4523297f6804f4cc71e 632 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 233 627 3.5E-89 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS11440 2b66433f1688c4523297f6804f4cc71e 632 SUPERFAMILY SSF56425 441 576 2.97E-30 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11440 2b66433f1688c4523297f6804f4cc71e 632 SUPERFAMILY SSF51905 237 433 2.98E-53 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11440 2b66433f1688c4523297f6804f4cc71e 632 SUPERFAMILY SSF51905 575 630 2.98E-53 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11440 2b66433f1688c4523297f6804f4cc71e 632 SUPERFAMILY SSF51905 123 186 2.98E-53 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11440 2b66433f1688c4523297f6804f4cc71e 632 Pfam PF04205 FMN-binding domain 35 107 2.6E-11 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS11440 2b66433f1688c4523297f6804f4cc71e 632 Gene3D G3DSA:3.50.50.60 119 188 6.9E-87 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11440 2b66433f1688c4523297f6804f4cc71e 632 Gene3D G3DSA:3.50.50.60 232 416 6.9E-87 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11440 2b66433f1688c4523297f6804f4cc71e 632 Gene3D G3DSA:3.50.50.60 572 630 6.9E-87 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11440 2b66433f1688c4523297f6804f4cc71e 632 Pfam PF00890 FAD binding domain 237 615 2.2E-56 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11440 2b66433f1688c4523297f6804f4cc71e 632 Pfam PF00890 FAD binding domain 135 217 5.4E-16 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11440 2b66433f1688c4523297f6804f4cc71e 632 SMART SM00900 35 109 2.4E-13 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS06715 7a4cb327dc598abff0cdc0033b736bef 216 Pfam PF12796 Ankyrin repeats (3 copies) 64 153 1.8E-13 T 26-04-2017 IPR020683 Ankyrin repeat-containing domain A4V04_RS06715 7a4cb327dc598abff0cdc0033b736bef 216 SUPERFAMILY SSF48403 31 210 1.09E-37 T 26-04-2017 IPR020683 Ankyrin repeat-containing domain A4V04_RS06715 7a4cb327dc598abff0cdc0033b736bef 216 SMART SM00248 123 152 9.0E-4 T 26-04-2017 IPR002110 Ankyrin repeat GO:0005515 A4V04_RS06715 7a4cb327dc598abff0cdc0033b736bef 216 SMART SM00248 156 185 2.2E-4 T 26-04-2017 IPR002110 Ankyrin repeat GO:0005515 A4V04_RS06715 7a4cb327dc598abff0cdc0033b736bef 216 SMART SM00248 92 121 0.82 T 26-04-2017 IPR002110 Ankyrin repeat GO:0005515 A4V04_RS06715 7a4cb327dc598abff0cdc0033b736bef 216 SMART SM00248 58 88 220.0 T 26-04-2017 IPR002110 Ankyrin repeat GO:0005515 A4V04_RS06715 7a4cb327dc598abff0cdc0033b736bef 216 Gene3D G3DSA:1.25.40.20 108 210 2.7E-27 T 26-04-2017 IPR020683 Ankyrin repeat-containing domain A4V04_RS06715 7a4cb327dc598abff0cdc0033b736bef 216 Gene3D G3DSA:1.25.40.20 31 107 8.6E-12 T 26-04-2017 IPR020683 Ankyrin repeat-containing domain A4V04_RS06715 7a4cb327dc598abff0cdc0033b736bef 216 Pfam PF00023 Ankyrin repeat 157 181 0.0032 T 26-04-2017 IPR002110 Ankyrin repeat GO:0005515 A4V04_RS06190 6720ed250b51219bc48ce63207132efa 220 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 20 172 3.1E-17 T 26-04-2017 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system A4V04_RS10485 c5e02ad9b11a15bbebf0a4b501790ae2 46 Pfam PF00468 Ribosomal protein L34 3 45 5.5E-21 T 26-04-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS10485 c5e02ad9b11a15bbebf0a4b501790ae2 46 ProSitePatterns PS00784 Ribosomal protein L34 signature. 4 23 - T 26-04-2017 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS10485 c5e02ad9b11a15bbebf0a4b501790ae2 46 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 2.3E-20 T 26-04-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS10485 c5e02ad9b11a15bbebf0a4b501790ae2 46 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 3 46 14.829 T 26-04-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS10485 c5e02ad9b11a15bbebf0a4b501790ae2 46 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 4 44 1.0E-9 T 26-04-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS09345 39984d1a4f30ee65089c8999e1fcbbf2 257 SMART SM00345 23 82 2.1E-15 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS09345 39984d1a4f30ee65089c8999e1fcbbf2 257 Gene3D G3DSA:3.40.1410.10 79 251 3.9E-27 T 26-04-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4V04_RS09345 39984d1a4f30ee65089c8999e1fcbbf2 257 Pfam PF07702 UTRA domain 113 250 2.6E-18 T 26-04-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4V04_RS09345 39984d1a4f30ee65089c8999e1fcbbf2 257 SUPERFAMILY SSF46785 15 86 2.47E-21 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09345 39984d1a4f30ee65089c8999e1fcbbf2 257 SMART SM00866 107 250 9.1E-7 T 26-04-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4V04_RS09345 39984d1a4f30ee65089c8999e1fcbbf2 257 Gene3D G3DSA:1.10.10.10 16 78 7.0E-24 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09345 39984d1a4f30ee65089c8999e1fcbbf2 257 SUPERFAMILY SSF64288 70 251 6.12E-25 T 26-04-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4V04_RS09345 39984d1a4f30ee65089c8999e1fcbbf2 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 3.3E-5 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS09345 39984d1a4f30ee65089c8999e1fcbbf2 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 3.3E-5 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS09345 39984d1a4f30ee65089c8999e1fcbbf2 257 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 82 6.4E-18 T 26-04-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4V04_RS07585 9746ee150d1c1a152d38bf2c5faf6361 375 Pfam PF00083 Sugar (and other) transporter 228 337 3.6E-7 T 26-04-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4V04_RS07585 9746ee150d1c1a152d38bf2c5faf6361 375 Gene3D G3DSA:1.20.1250.20 184 371 5.4E-24 T 26-04-2017 A4V04_RS07585 9746ee150d1c1a152d38bf2c5faf6361 375 SUPERFAMILY SSF103473 3 372 3.4E-62 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS07585 9746ee150d1c1a152d38bf2c5faf6361 375 Pfam PF07690 Major Facilitator Superfamily 3 222 3.4E-33 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS07585 9746ee150d1c1a152d38bf2c5faf6361 375 Gene3D G3DSA:1.20.1250.20 3 178 3.7E-34 T 26-04-2017 A4V04_RS05795 75fa6b84ecc4a513687d89a6573bc7cb 150 Gene3D G3DSA:2.40.280.10 3 122 6.9E-47 T 26-04-2017 IPR023620 Small protein B A4V04_RS05795 75fa6b84ecc4a513687d89a6573bc7cb 150 Hamap MF_00023 SsrA-binding protein [smpB]. 1 150 66.075 T 26-04-2017 IPR000037 SsrA-binding protein GO:0003723 A4V04_RS05795 75fa6b84ecc4a513687d89a6573bc7cb 150 ProSitePatterns PS01317 SsrA-binding protein. 21 33 - T 26-04-2017 IPR020081 SsrA-binding protein, conserved site A4V04_RS05795 75fa6b84ecc4a513687d89a6573bc7cb 150 TIGRFAM TIGR00086 smpB: SsrA-binding protein 3 145 2.0E-50 T 26-04-2017 IPR000037 SsrA-binding protein GO:0003723 A4V04_RS05795 75fa6b84ecc4a513687d89a6573bc7cb 150 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 3 127 7.0E-44 T 26-04-2017 IPR000037 SsrA-binding protein GO:0003723 A4V04_RS05795 75fa6b84ecc4a513687d89a6573bc7cb 150 Pfam PF01668 SmpB protein 3 64 3.2E-26 T 26-04-2017 IPR000037 SsrA-binding protein GO:0003723 A4V04_RS05795 75fa6b84ecc4a513687d89a6573bc7cb 150 SUPERFAMILY SSF74982 3 127 4.32E-46 T 26-04-2017 IPR023620 Small protein B A4V04_RS03445 e3d56fc30e3a48d6b1af9d5627f03426 503 Pfam PF00817 impB/mucB/samB family 11 195 2.6E-24 T 26-04-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4V04_RS03445 e3d56fc30e3a48d6b1af9d5627f03426 503 Gene3D G3DSA:3.30.70.270 108 198 1.3E-20 T 26-04-2017 A4V04_RS03445 e3d56fc30e3a48d6b1af9d5627f03426 503 Pfam PF11799 impB/mucB/samB family C-terminal domain 296 419 5.1E-13 T 26-04-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4V04_RS03445 e3d56fc30e3a48d6b1af9d5627f03426 503 Gene3D G3DSA:1.10.150.20 220 283 4.5E-9 T 26-04-2017 A4V04_RS03445 e3d56fc30e3a48d6b1af9d5627f03426 503 SUPERFAMILY SSF56672 6 80 4.89E-41 T 26-04-2017 A4V04_RS03445 e3d56fc30e3a48d6b1af9d5627f03426 503 SUPERFAMILY SSF56672 114 285 4.89E-41 T 26-04-2017 A4V04_RS06215 a105b53eb3476364e38bbc0fc71327d4 385 Pfam PF08401 Domain of unknown function (DUF1738) 26 124 7.2E-31 T 26-04-2017 IPR013610 Domain of unknown function DUF1738 A4V04_RS05020 e0189fcc5760a69db03e8e6b7c3de2fa 465 Pfam PF03315 Serine dehydratase beta chain 4 157 6.5E-57 T 26-04-2017 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A4V04_RS05020 e0189fcc5760a69db03e8e6b7c3de2fa 465 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 461 4.0E-205 T 26-04-2017 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A4V04_RS05020 e0189fcc5760a69db03e8e6b7c3de2fa 465 Gene3D G3DSA:3.30.1330.90 11 159 1.6E-54 T 26-04-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A4V04_RS05020 e0189fcc5760a69db03e8e6b7c3de2fa 465 Pfam PF03313 Serine dehydratase alpha chain 193 459 7.5E-101 T 26-04-2017 IPR005130 Serine dehydratase-like, alpha subunit A4V04_RS05020 e0189fcc5760a69db03e8e6b7c3de2fa 465 SUPERFAMILY SSF143548 17 158 3.4E-43 T 26-04-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A4V04_RS12290 977e4d1a20efff825da96c58594b1046 158 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 148 1.1E-51 T 26-04-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A4V04_RS12290 977e4d1a20efff825da96c58594b1046 158 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 156 70.945 T 26-04-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A4V04_RS12290 977e4d1a20efff825da96c58594b1046 158 Pfam PF03477 ATP cone domain 52 137 8.7E-14 T 26-04-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A4V04_RS02470 98ef89d4130b43ed5867a647586e13e5 322 Pfam PF02073 Thermophilic metalloprotease (M29) 123 286 4.6E-8 T 26-04-2017 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 A4V04_RS02470 98ef89d4130b43ed5867a647586e13e5 322 SUPERFAMILY SSF144052 3 315 1.57E-49 T 26-04-2017 A4V04_RS11215 3189d36ffab2ae7dd6e1cbf35f7d742a 487 SUPERFAMILY SSF56425 276 424 5.23E-17 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11215 3189d36ffab2ae7dd6e1cbf35f7d742a 487 SUPERFAMILY SSF51905 27 272 5.9E-54 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11215 3189d36ffab2ae7dd6e1cbf35f7d742a 487 SUPERFAMILY SSF51905 424 483 5.9E-54 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11215 3189d36ffab2ae7dd6e1cbf35f7d742a 487 Gene3D G3DSA:3.50.50.60 25 266 3.0E-82 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11215 3189d36ffab2ae7dd6e1cbf35f7d742a 487 Gene3D G3DSA:3.50.50.60 421 484 3.0E-82 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS11215 3189d36ffab2ae7dd6e1cbf35f7d742a 487 Gene3D G3DSA:3.90.700.10 290 414 1.9E-17 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11215 3189d36ffab2ae7dd6e1cbf35f7d742a 487 Pfam PF00890 FAD binding domain 35 465 5.3E-61 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS11215 3189d36ffab2ae7dd6e1cbf35f7d742a 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 429 451 3.2E-6 T 26-04-2017 A4V04_RS11215 3189d36ffab2ae7dd6e1cbf35f7d742a 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 36 55 3.2E-6 T 26-04-2017 A4V04_RS08705 88514375f8e863b53885bb22d1dfbac0 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 5.0E-8 T 26-04-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4V04_RS08705 88514375f8e863b53885bb22d1dfbac0 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 5.0E-8 T 26-04-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4V04_RS08705 88514375f8e863b53885bb22d1dfbac0 197 Gene3D G3DSA:1.10.357.10 8 186 1.4E-26 T 26-04-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4V04_RS08705 88514375f8e863b53885bb22d1dfbac0 197 SUPERFAMILY SSF46689 5 73 2.15E-16 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS08705 88514375f8e863b53885bb22d1dfbac0 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 55 2.1E-12 T 26-04-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4V04_RS00980 9bb3eb0e21f27d35afb86f3e3c109e6b 476 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 250 466 1.5E-44 T 26-04-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A4V04_RS00980 9bb3eb0e21f27d35afb86f3e3c109e6b 476 SMART SM00646 311 466 1.4E-57 T 26-04-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A4V04_RS00980 9bb3eb0e21f27d35afb86f3e3c109e6b 476 Gene3D G3DSA:3.40.630.40 394 469 1.9E-54 T 26-04-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A4V04_RS00980 9bb3eb0e21f27d35afb86f3e3c109e6b 476 Gene3D G3DSA:3.40.630.40 249 346 1.9E-54 T 26-04-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A4V04_RS00980 9bb3eb0e21f27d35afb86f3e3c109e6b 476 SUPERFAMILY SSF53187 393 469 8.16E-50 T 26-04-2017 A4V04_RS00980 9bb3eb0e21f27d35afb86f3e3c109e6b 476 SUPERFAMILY SSF53187 249 345 8.16E-50 T 26-04-2017 A4V04_RS00980 9bb3eb0e21f27d35afb86f3e3c109e6b 476 Pfam PF11741 AMIN domain 35 140 2.1E-12 T 26-04-2017 IPR021731 AMIN domain A4V04_RS06315 53166d2776e1749ca1d83f0f73fbb120 535 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 41 270 9.8E-23 T 26-04-2017 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 A4V04_RS05670 529335336f67de309c60b5330c37995a 381 SUPERFAMILY SSF102114 3 378 1.96E-103 T 26-04-2017 A4V04_RS05670 529335336f67de309c60b5330c37995a 381 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 5 369 1.0E-102 T 26-04-2017 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 A4V04_RS05670 529335336f67de309c60b5330c37995a 381 Pfam PF04055 Radical SAM superfamily 9 177 1.2E-19 T 26-04-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 A4V04_RS05670 529335336f67de309c60b5330c37995a 381 Gene3D G3DSA:3.80.30.20 6 237 2.1E-31 T 26-04-2017 IPR023404 Radical SAM, alpha/beta horseshoe A4V04_RS05670 529335336f67de309c60b5330c37995a 381 SMART SM00729 3 220 1.3E-48 T 26-04-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4V04_RS05670 529335336f67de309c60b5330c37995a 381 Pfam PF06969 HemN C-terminal domain 305 367 2.8E-10 T 26-04-2017 IPR010723 HemN, C-terminal A4V04_RS02695 e7383d64bd1bbbe65d781a044dbda61d 369 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 114 338 1.2E-44 T 26-04-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A4V04_RS02695 e7383d64bd1bbbe65d781a044dbda61d 369 Gene3D G3DSA:3.40.710.10 115 355 4.4E-60 T 26-04-2017 IPR012338 Beta-lactamase/transpeptidase-like A4V04_RS02695 e7383d64bd1bbbe65d781a044dbda61d 369 SUPERFAMILY SSF56601 1 29 4.18E-53 T 26-04-2017 IPR012338 Beta-lactamase/transpeptidase-like A4V04_RS02695 e7383d64bd1bbbe65d781a044dbda61d 369 SUPERFAMILY SSF56601 119 358 4.18E-53 T 26-04-2017 IPR012338 Beta-lactamase/transpeptidase-like A4V04_RS02695 e7383d64bd1bbbe65d781a044dbda61d 369 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 223 236 4.5E-10 T 26-04-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4V04_RS02695 e7383d64bd1bbbe65d781a044dbda61d 369 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 196 213 4.5E-10 T 26-04-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4V04_RS02695 e7383d64bd1bbbe65d781a044dbda61d 369 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 147 158 4.5E-10 T 26-04-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4V04_RS06980 19f5328764026d1063c24eb19f89828c 72 Gene3D G3DSA:2.40.50.200 2 71 5.3E-24 T 26-04-2017 IPR005220 Bacterial OB-fold A4V04_RS06980 19f5328764026d1063c24eb19f89828c 72 SUPERFAMILY SSF101756 2 70 1.96E-21 T 26-04-2017 IPR005220 Bacterial OB-fold A4V04_RS06980 19f5328764026d1063c24eb19f89828c 72 Pfam PF04076 Bacterial OB fold (BOF) protein 2 69 1.6E-19 T 26-04-2017 IPR005220 Bacterial OB-fold A4V04_RS09575 cce2fe015dd9d565a1d63e4f988994d0 286 Gene3D G3DSA:2.60.120.10 39 180 7.3E-4 T 26-04-2017 IPR014710 RmlC-like jelly roll fold A4V04_RS09575 cce2fe015dd9d565a1d63e4f988994d0 286 SUPERFAMILY SSF51206 41 153 1.52E-5 T 26-04-2017 IPR018490 Cyclic nucleotide-binding-like A4V04_RS06995 614be5549737f10f2468b352466001f4 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 261 3.3E-22 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS06995 614be5549737f10f2468b352466001f4 276 Gene3D G3DSA:1.10.3720.10 71 262 2.5E-19 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS06995 614be5549737f10f2468b352466001f4 276 SUPERFAMILY SSF161098 72 255 1.31E-27 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS03050 571bd7a555254c31a119f78673154974 406 Gene3D G3DSA:3.40.1710.10 52 186 9.8E-4 T 26-04-2017 A4V04_RS03050 571bd7a555254c31a119f78673154974 406 Pfam PF12698 ABC-2 family transporter protein 24 375 9.5E-32 T 26-04-2017 A4V04_RS09265 53d6937256a4e7bc81a6a260f0e40d9f 362 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 153 212 7.8E-8 T 26-04-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A4V04_RS09265 53d6937256a4e7bc81a6a260f0e40d9f 362 SUPERFAMILY SSF81301 2 124 2.29E-28 T 26-04-2017 A4V04_RS09265 53d6937256a4e7bc81a6a260f0e40d9f 362 Pfam PF01743 Poly A polymerase head domain 4 127 1.6E-18 T 26-04-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A4V04_RS09265 53d6937256a4e7bc81a6a260f0e40d9f 362 Gene3D G3DSA:1.10.3090.10 127 325 4.6E-33 T 26-04-2017 A4V04_RS09265 53d6937256a4e7bc81a6a260f0e40d9f 362 Gene3D G3DSA:3.30.460.10 2 126 2.8E-29 T 26-04-2017 A4V04_RS09265 53d6937256a4e7bc81a6a260f0e40d9f 362 SUPERFAMILY SSF81891 125 325 2.09E-34 T 26-04-2017 A4V04_RS09990 a97f39a8273b72977c8b1defa82373a7 176 Hamap MF_00163 Peptide deformylase [def]. 2 163 29.741 T 26-04-2017 IPR023635 Peptide deformylase A4V04_RS09990 a97f39a8273b72977c8b1defa82373a7 176 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 158 2.9E-52 T 26-04-2017 IPR023635 Peptide deformylase A4V04_RS09990 a97f39a8273b72977c8b1defa82373a7 176 PIRSF PIRSF004749 1 176 2.9E-57 T 26-04-2017 IPR023635 Peptide deformylase A4V04_RS09990 a97f39a8273b72977c8b1defa82373a7 176 Pfam PF01327 Polypeptide deformylase 4 153 6.5E-52 T 26-04-2017 IPR023635 Peptide deformylase A4V04_RS09990 a97f39a8273b72977c8b1defa82373a7 176 PRINTS PR01576 Peptide deformylase signature 121 150 2.4E-36 T 26-04-2017 IPR023635 Peptide deformylase A4V04_RS09990 a97f39a8273b72977c8b1defa82373a7 176 PRINTS PR01576 Peptide deformylase signature 90 101 2.4E-36 T 26-04-2017 IPR023635 Peptide deformylase A4V04_RS09990 a97f39a8273b72977c8b1defa82373a7 176 PRINTS PR01576 Peptide deformylase signature 102 120 2.4E-36 T 26-04-2017 IPR023635 Peptide deformylase A4V04_RS09990 a97f39a8273b72977c8b1defa82373a7 176 PRINTS PR01576 Peptide deformylase signature 33 62 2.4E-36 T 26-04-2017 IPR023635 Peptide deformylase A4V04_RS09990 a97f39a8273b72977c8b1defa82373a7 176 Gene3D G3DSA:3.90.45.10 4 169 3.3E-66 T 26-04-2017 IPR023635 Peptide deformylase A4V04_RS09990 a97f39a8273b72977c8b1defa82373a7 176 SUPERFAMILY SSF56420 2 163 1.7E-60 T 26-04-2017 IPR023635 Peptide deformylase A4V04_RS12835 2f1edaf5090f39e8c0ba9413d1cbcab8 269 Gene3D G3DSA:3.30.420.40 103 241 5.0E-48 T 26-04-2017 A4V04_RS12835 2f1edaf5090f39e8c0ba9413d1cbcab8 269 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 4 261 3.6E-61 T 26-04-2017 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 A4V04_RS12835 2f1edaf5090f39e8c0ba9413d1cbcab8 269 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 3 259 1.9E-70 T 26-04-2017 IPR008275 CoA enzyme activase A4V04_RS12835 2f1edaf5090f39e8c0ba9413d1cbcab8 269 SUPERFAMILY SSF53067 1 264 2.73E-35 T 26-04-2017 A4V04_RS08605 34ff07ddfa209b2f38b23e9f1d2b79a5 430 Gene3D G3DSA:3.40.50.10070 31 153 3.5E-38 T 26-04-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 A4V04_RS08605 34ff07ddfa209b2f38b23e9f1d2b79a5 430 Pfam PF04052 TolB amino-terminal domain 32 129 1.1E-22 T 26-04-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 A4V04_RS08605 34ff07ddfa209b2f38b23e9f1d2b79a5 430 Pfam PF07676 WD40-like Beta Propeller Repeat 195 226 2.4E-7 T 26-04-2017 IPR011659 WD40-like Beta Propeller A4V04_RS08605 34ff07ddfa209b2f38b23e9f1d2b79a5 430 Pfam PF07676 WD40-like Beta Propeller Repeat 241 270 5.1E-6 T 26-04-2017 IPR011659 WD40-like Beta Propeller A4V04_RS08605 34ff07ddfa209b2f38b23e9f1d2b79a5 430 Pfam PF07676 WD40-like Beta Propeller Repeat 371 397 1.2E-4 T 26-04-2017 IPR011659 WD40-like Beta Propeller A4V04_RS08605 34ff07ddfa209b2f38b23e9f1d2b79a5 430 Pfam PF07676 WD40-like Beta Propeller Repeat 279 315 6.4E-15 T 26-04-2017 IPR011659 WD40-like Beta Propeller A4V04_RS08605 34ff07ddfa209b2f38b23e9f1d2b79a5 430 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 22 426 2.0E-140 T 26-04-2017 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 A4V04_RS08605 34ff07ddfa209b2f38b23e9f1d2b79a5 430 SUPERFAMILY SSF69304 162 427 1.96E-58 T 26-04-2017 A4V04_RS08605 34ff07ddfa209b2f38b23e9f1d2b79a5 430 Hamap MF_00671 Protein TolB [tolB]. 12 425 32.222 T 26-04-2017 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 A4V04_RS08605 34ff07ddfa209b2f38b23e9f1d2b79a5 430 Gene3D G3DSA:2.130.10.10 154 427 7.8E-76 T 26-04-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A4V04_RS08605 34ff07ddfa209b2f38b23e9f1d2b79a5 430 SUPERFAMILY SSF52964 39 162 5.23E-32 T 26-04-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 A4V04_RS04460 14d8048365b6669d8ae54c28bc3cfb46 154 SUPERFAMILY SSF55826 6 146 2.35E-31 T 26-04-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4V04_RS04460 14d8048365b6669d8ae54c28bc3cfb46 154 Gene3D G3DSA:3.90.960.10 4 153 4.6E-39 T 26-04-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4V04_RS04460 14d8048365b6669d8ae54c28bc3cfb46 154 Pfam PF04073 Aminoacyl-tRNA editing domain 25 143 8.0E-25 T 26-04-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4V04_RS10295 b925eb981362af99dd9e072f77f41c72 106 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 93 6.3E-12 T 26-04-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4V04_RS10295 b925eb981362af99dd9e072f77f41c72 106 SUPERFAMILY SSF143011 1 92 5.49E-5 T 26-04-2017 A4V04_RS01805 20e7c5e6d512c2a1a2cf4a91b3c01023 906 Pfam PF12846 AAA-like domain 506 818 6.3E-14 T 26-04-2017 A4V04_RS01805 20e7c5e6d512c2a1a2cf4a91b3c01023 906 TIGRFAM TIGR02746 TraC-F-type: type-IV secretion system protein TraC 72 902 8.2E-186 T 26-04-2017 IPR014117 Type-IV secretion system protein TraC A4V04_RS01805 20e7c5e6d512c2a1a2cf4a91b3c01023 906 SUPERFAMILY SSF52540 457 642 4.82E-42 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01805 20e7c5e6d512c2a1a2cf4a91b3c01023 906 SUPERFAMILY SSF52540 676 813 4.82E-42 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01805 20e7c5e6d512c2a1a2cf4a91b3c01023 906 Pfam PF11130 F pilus assembly Type-IV secretion system for plasmid transfer 47 299 7.2E-37 T 26-04-2017 IPR025955 Type-IV secretion system protein TraC/Conjugative transfer ATPase A4V04_RS01805 20e7c5e6d512c2a1a2cf4a91b3c01023 906 Gene3D G3DSA:3.40.50.300 502 583 1.2E-24 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01805 20e7c5e6d512c2a1a2cf4a91b3c01023 906 Gene3D G3DSA:3.40.50.300 696 819 1.2E-24 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05135 a9896c48d8cebbeefd2080f99651305c 300 SUPERFAMILY SSF103481 44 149 5.62E-7 T 26-04-2017 A4V04_RS05135 a9896c48d8cebbeefd2080f99651305c 300 SUPERFAMILY SSF103481 202 295 1.05E-11 T 26-04-2017 A4V04_RS05135 a9896c48d8cebbeefd2080f99651305c 300 Pfam PF00892 EamA-like transporter family 8 147 1.1E-10 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS05135 a9896c48d8cebbeefd2080f99651305c 300 Pfam PF00892 EamA-like transporter family 160 292 5.6E-19 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS10165 2559e91203ae2d4bd39d69291a9832ed 242 Pfam PF13739 Domain of unknown function (DUF4163) 47 130 3.2E-13 T 26-04-2017 IPR025303 Domain of unknown function DUF4163 A4V04_RS10165 2559e91203ae2d4bd39d69291a9832ed 242 Gene3D G3DSA:3.90.640.20 148 234 5.7E-10 T 26-04-2017 IPR021729 Domain of unknown function DUF3298 A4V04_RS10165 2559e91203ae2d4bd39d69291a9832ed 242 Pfam PF11738 Protein of unknown function (DUF3298) 149 226 2.3E-11 T 26-04-2017 IPR021729 Domain of unknown function DUF3298 A4V04_RS10165 2559e91203ae2d4bd39d69291a9832ed 242 Gene3D G3DSA:3.30.565.40 45 145 2.1E-21 T 26-04-2017 IPR025303 Domain of unknown function DUF4163 A4V04_RS06250 78ef13b9b5c6bbefe0e24d79584c64ee 354 SUPERFAMILY SSF52540 16 127 1.41E-45 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06250 78ef13b9b5c6bbefe0e24d79584c64ee 354 SUPERFAMILY SSF52540 159 338 1.41E-45 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06250 78ef13b9b5c6bbefe0e24d79584c64ee 354 Pfam PF00437 Type II/IV secretion system protein 17 332 1.6E-55 T 26-04-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A4V04_RS06250 78ef13b9b5c6bbefe0e24d79584c64ee 354 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 179 192 - T 26-04-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A4V04_RS06250 78ef13b9b5c6bbefe0e24d79584c64ee 354 Gene3D G3DSA:3.40.50.300 166 343 2.0E-38 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06250 78ef13b9b5c6bbefe0e24d79584c64ee 354 TIGRFAM TIGR02788 VirB11: P-type DNA transfer ATPase VirB11 22 344 7.3E-105 T 26-04-2017 IPR014155 Type IV secretion system protein VirB11 GO:0005737|GO:0006810|GO:0009405 A4V04_RS06250 78ef13b9b5c6bbefe0e24d79584c64ee 354 Gene3D G3DSA:3.30.450.90 17 113 1.3E-26 T 26-04-2017 A4V04_RS12285 d5d18a7514b1e645d09d1c65a474d987 363 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 93 - T 26-04-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A4V04_RS12285 d5d18a7514b1e645d09d1c65a474d987 363 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 9 356 1.9E-113 T 26-04-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 A4V04_RS12285 d5d18a7514b1e645d09d1c65a474d987 363 Gene3D G3DSA:3.40.140.10 5 133 1.2E-35 T 26-04-2017 A4V04_RS12285 d5d18a7514b1e645d09d1c65a474d987 363 Gene3D G3DSA:3.40.430.10 134 359 1.2E-71 T 26-04-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4V04_RS12285 d5d18a7514b1e645d09d1c65a474d987 363 Pfam PF01872 RibD C-terminal domain 152 355 1.4E-47 T 26-04-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4V04_RS12285 d5d18a7514b1e645d09d1c65a474d987 363 PIRSF PIRSF006769 1 362 3.1E-120 T 26-04-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 A4V04_RS12285 d5d18a7514b1e645d09d1c65a474d987 363 SUPERFAMILY SSF53927 5 150 5.52E-46 T 26-04-2017 IPR016193 Cytidine deaminase-like GO:0003824 A4V04_RS12285 d5d18a7514b1e645d09d1c65a474d987 363 SUPERFAMILY SSF53597 149 357 3.78E-58 T 26-04-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4V04_RS12285 d5d18a7514b1e645d09d1c65a474d987 363 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 151 360 4.3E-54 T 26-04-2017 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 A4V04_RS12285 d5d18a7514b1e645d09d1c65a474d987 363 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 104 2.8E-20 T 26-04-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 A4V04_RS10030 a79add0add54ba809ebf1c12f506f1a5 340 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 254 2.2E-30 T 26-04-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4V04_RS10030 a79add0add54ba809ebf1c12f506f1a5 340 Gene3D G3DSA:3.40.190.10 32 125 8.3E-19 T 26-04-2017 A4V04_RS10030 a79add0add54ba809ebf1c12f506f1a5 340 Gene3D G3DSA:3.40.190.10 224 254 8.3E-19 T 26-04-2017 A4V04_RS10030 a79add0add54ba809ebf1c12f506f1a5 340 SUPERFAMILY SSF53850 26 256 1.93E-49 T 26-04-2017 A4V04_RS10030 a79add0add54ba809ebf1c12f506f1a5 340 SMART SM00062 35 264 2.8E-50 T 26-04-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4V04_RS10030 a79add0add54ba809ebf1c12f506f1a5 340 Gene3D G3DSA:3.40.190.10 126 223 1.4E-13 T 26-04-2017 A4V04_RS12840 cda87420658b6536c36324a73e44e476 437 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 71 425 2.2E-39 T 26-04-2017 IPR010327 FldB/FldC dehydratase alpha/beta subunit A4V04_RS02240 3fef9be9c2e3798750933f1c6e9956d6 360 SUPERFAMILY SSF56935 20 360 1.36E-50 T 26-04-2017 A4V04_RS02240 3fef9be9c2e3798750933f1c6e9956d6 360 Pfam PF13609 Gram-negative porin 13 325 1.8E-36 T 26-04-2017 A4V04_RS02240 3fef9be9c2e3798750933f1c6e9956d6 360 Gene3D G3DSA:2.40.160.10 20 360 6.3E-64 T 26-04-2017 IPR023614 Porin domain A4V04_RS00430 a0408f89d00cc1f89ec130cc7e82bcd8 201 Pfam PF16778 Phage tail assembly chaperone protein 112 179 2.7E-16 T 26-04-2017 IPR031893 Phage tail assembly chaperone protein A4V04_RS04890 f3639b7d3d477502c1a3c361d014edf1 324 Hamap MF_00301 Homoserine kinase [thrB]. 1 324 123.576 T 26-04-2017 IPR005280 Homoserine kinase ThrB GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A4V04_RS04890 f3639b7d3d477502c1a3c361d014edf1 324 Pfam PF01636 Phosphotransferase enzyme family 30 256 2.5E-24 T 26-04-2017 IPR002575 Aminoglycoside phosphotransferase A4V04_RS04890 f3639b7d3d477502c1a3c361d014edf1 324 Gene3D G3DSA:3.30.200.20 1 103 2.5E-35 T 26-04-2017 A4V04_RS04890 f3639b7d3d477502c1a3c361d014edf1 324 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 311 1.1E-92 T 26-04-2017 IPR005280 Homoserine kinase ThrB GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A4V04_RS04890 f3639b7d3d477502c1a3c361d014edf1 324 SUPERFAMILY SSF56112 5 315 3.06E-65 T 26-04-2017 IPR011009 Protein kinase-like domain A4V04_RS04890 f3639b7d3d477502c1a3c361d014edf1 324 Gene3D G3DSA:3.90.1200.10 106 315 1.7E-57 T 26-04-2017 A4V04_RS03460 2b73138b72f670394a3db56b030834d3 424 ProSitePatterns PS01007 Transposases, Mutator family, signature. 254 278 - T 26-04-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4V04_RS03460 2b73138b72f670394a3db56b030834d3 424 Pfam PF00872 Transposase, Mutator family 36 401 2.8E-110 T 26-04-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4V04_RS07420 37e96793a4622d2291e178348946d183 428 Gene3D G3DSA:3.90.1720.10 255 380 7.9E-23 T 26-04-2017 IPR000064 Endopeptidase, NLPC/P60 domain A4V04_RS07420 37e96793a4622d2291e178348946d183 428 Pfam PF00877 NlpC/P60 family 271 359 2.7E-16 T 26-04-2017 IPR000064 Endopeptidase, NLPC/P60 domain A4V04_RS07420 37e96793a4622d2291e178348946d183 428 Pfam PF06347 Bacterial SH3 domain 120 165 1.3E-4 T 26-04-2017 IPR010466 Protein of unknown function DUF1058 A4V04_RS07420 37e96793a4622d2291e178348946d183 428 SUPERFAMILY SSF54001 256 356 5.4E-21 T 26-04-2017 A4V04_RS12750 8d1dcb0c901c43d81a5d58c488e73361 232 SUPERFAMILY SSF143422 31 119 1.03E-9 T 26-04-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS12750 8d1dcb0c901c43d81a5d58c488e73361 232 SMART SM01321 10 125 5.6E-4 T 26-04-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS01555 49086b120da4bffaaef7d975c838cc4f 92 SUPERFAMILY SSF143011 1 92 5.36E-15 T 26-04-2017 A4V04_RS01555 49086b120da4bffaaef7d975c838cc4f 92 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 4 92 9.0E-22 T 26-04-2017 IPR007711 Toxin HigB-1 A4V04_RS05825 869c09bbfb3a09daa74522686da9955a 288 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 14 285 71.34 T 26-04-2017 IPR026530 Phosphoenolpyruvate synthase regulatory protein A4V04_RS05825 869c09bbfb3a09daa74522686da9955a 288 Pfam PF03618 Kinase/pyrophosphorylase 17 275 1.6E-79 T 26-04-2017 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 A4V04_RS02950 823d8ffa89c34d3cbdfd37daf19fa518 92 PIRSF PIRSF006156 1 89 3.3E-23 T 26-04-2017 IPR004386 Toxin-antitoxin system, YafQ-like toxin A4V04_RS02950 823d8ffa89c34d3cbdfd37daf19fa518 92 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 4 87 4.0E-20 T 26-04-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4V04_RS02950 823d8ffa89c34d3cbdfd37daf19fa518 92 Pfam PF15738 Bacterial toxin of type II toxin-antitoxin system, YafQ 3 88 6.7E-26 T 26-04-2017 IPR004386 Toxin-antitoxin system, YafQ-like toxin A4V04_RS02950 823d8ffa89c34d3cbdfd37daf19fa518 92 SUPERFAMILY SSF143011 1 87 2.09E-19 T 26-04-2017 A4V04_RS08905 2254a543dfe489c35e766880933c4591 428 Gene3D G3DSA:2.40.50.100 82 115 8.9E-17 T 26-04-2017 A4V04_RS08905 2254a543dfe489c35e766880933c4591 428 Gene3D G3DSA:2.40.50.100 207 237 8.9E-17 T 26-04-2017 A4V04_RS08905 2254a543dfe489c35e766880933c4591 428 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 68 319 2.3E-18 T 26-04-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A4V04_RS08905 2254a543dfe489c35e766880933c4591 428 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 59 340 2.5E-41 T 26-04-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 A4V04_RS08905 2254a543dfe489c35e766880933c4591 428 SUPERFAMILY SSF111369 70 324 1.7E-18 T 26-04-2017 A4V04_RS10355 b8a0a38bef9132b0bb3f1e8fd6d46625 125 SUPERFAMILY SSF48695 10 123 2.19E-12 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS10355 b8a0a38bef9132b0bb3f1e8fd6d46625 125 Gene3D G3DSA:3.90.10.10 21 123 3.7E-8 T 26-04-2017 A4V04_RS08430 dd7e0f39ebe03fdb4d364dfbdc5c1d46 400 PIRSF PIRSF019422 1 399 2.9E-110 T 26-04-2017 IPR026044 Membrane-bound lytic murein transglycosylase A A4V04_RS08430 dd7e0f39ebe03fdb4d364dfbdc5c1d46 400 SUPERFAMILY SSF50685 41 396 5.58E-112 T 26-04-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain A4V04_RS08430 dd7e0f39ebe03fdb4d364dfbdc5c1d46 400 Gene3D G3DSA:2.40.40.10 51 196 6.5E-20 T 26-04-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain A4V04_RS08430 dd7e0f39ebe03fdb4d364dfbdc5c1d46 400 Gene3D G3DSA:2.40.40.10 205 394 1.6E-53 T 26-04-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain A4V04_RS08430 dd7e0f39ebe03fdb4d364dfbdc5c1d46 400 Pfam PF06725 3D domain 317 389 1.4E-22 T 26-04-2017 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 A4V04_RS08430 dd7e0f39ebe03fdb4d364dfbdc5c1d46 400 Pfam PF03562 MltA specific insert domain 57 293 3.4E-73 T 26-04-2017 IPR005300 Lytic transglycosylase MltA GO:0004553 A4V04_RS08430 dd7e0f39ebe03fdb4d364dfbdc5c1d46 400 SMART SM00925 137 293 5.4E-69 T 26-04-2017 IPR005300 Lytic transglycosylase MltA GO:0004553 A4V04_RS00900 8cbec10a6f0e2f4222a163ca3e4737a7 319 Pfam PF04015 Domain of unknown function (DUF362) 102 275 2.7E-12 T 26-04-2017 IPR007160 Domain of unknown function DUF362 A4V04_RS07705 75a03d94d1a279090f16ab9a1213aa9c 201 Pfam PF05728 Uncharacterised protein family (UPF0227) 13 195 3.2E-38 T 26-04-2017 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA A4V04_RS07705 75a03d94d1a279090f16ab9a1213aa9c 201 SUPERFAMILY SSF53474 14 197 1.32E-17 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS07705 75a03d94d1a279090f16ab9a1213aa9c 201 Gene3D G3DSA:3.40.50.1820 12 187 5.8E-13 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS09720 d14febf7fdfc46332a10ca15c23f41e5 320 SUPERFAMILY SSF52768 7 308 5.94E-71 T 26-04-2017 A4V04_RS09720 d14febf7fdfc46332a10ca15c23f41e5 320 Gene3D G3DSA:3.40.800.10 8 307 3.4E-78 T 26-04-2017 IPR023696 Ureohydrolase domain A4V04_RS09720 d14febf7fdfc46332a10ca15c23f41e5 320 PIRSF PIRSF036979 13 308 1.6E-63 T 26-04-2017 IPR006035 Ureohydrolase GO:0046872 A4V04_RS09720 d14febf7fdfc46332a10ca15c23f41e5 320 Pfam PF00491 Arginase family 31 299 5.5E-64 T 26-04-2017 IPR006035 Ureohydrolase GO:0046872 A4V04_RS04410 db11ed3f6a5cc8e967253e7e692ca1f8 241 Pfam PF04474 Protein of unknown function (DUF554) 4 235 1.3E-68 T 26-04-2017 IPR007563 Protein of unknown function DUF554 A4V04_RS04265 2332b6ace5695bcf97ad9ae9d297ce66 444 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 8 370 1.2E-136 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS04265 2332b6ace5695bcf97ad9ae9d297ce66 444 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 8 442 9.6E-178 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS04265 2332b6ace5695bcf97ad9ae9d297ce66 444 PIRSF PIRSF004539 3 444 2.4E-165 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS12050 8f5e73fa37707f297d6ba68149ed2b92 115 Pfam PF04999 Cell division protein FtsL 9 90 1.8E-8 T 26-04-2017 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 A4V04_RS12050 8f5e73fa37707f297d6ba68149ed2b92 115 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 10 89 4.4E-13 T 26-04-2017 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 A4V04_RS01560 c3a7fe8005471ccfacd9c2ee11396571 108 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 4 84 3.1E-25 T 26-04-2017 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 A4V04_RS01560 c3a7fe8005471ccfacd9c2ee11396571 108 Gene3D G3DSA:1.10.260.40 3 83 5.6E-29 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS01560 c3a7fe8005471ccfacd9c2ee11396571 108 SUPERFAMILY SSF47413 9 92 1.21E-21 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS01560 c3a7fe8005471ccfacd9c2ee11396571 108 Pfam PF01381 Helix-turn-helix 15 61 3.6E-10 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS01560 c3a7fe8005471ccfacd9c2ee11396571 108 SMART SM00530 13 68 2.8E-7 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS07990 c06508b9282508d18cfb4a00c4bc987e 192 Gene3D G3DSA:3.30.70.20 126 189 1.9E-24 T 26-04-2017 A4V04_RS07990 c06508b9282508d18cfb4a00c4bc987e 192 Gene3D G3DSA:3.30.70.20 7 74 1.9E-24 T 26-04-2017 A4V04_RS07990 c06508b9282508d18cfb4a00c4bc987e 192 Gene3D G3DSA:3.30.70.20 75 125 5.0E-18 T 26-04-2017 A4V04_RS07990 c06508b9282508d18cfb4a00c4bc987e 192 SUPERFAMILY SSF54862 5 189 3.56E-50 T 26-04-2017 A4V04_RS07990 c06508b9282508d18cfb4a00c4bc987e 192 Pfam PF13247 4Fe-4S dicluster domain 66 156 7.8E-18 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS07990 c06508b9282508d18cfb4a00c4bc987e 192 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS04485 aeb7837762a2ad77de1716d2f5943e4e 549 Pfam PF05598 Transposase domain (DUF772) 51 119 2.3E-7 T 26-04-2017 IPR008490 Transposase InsH, N-terminal A4V04_RS04485 aeb7837762a2ad77de1716d2f5943e4e 549 Pfam PF13751 Transposase DDE domain 387 491 1.7E-21 T 26-04-2017 IPR025668 Transposase DDE domain A4V04_RS08770 c2c98bbd54df93298ed0996489bfda85 278 SUPERFAMILY SSF53448 2 270 2.48E-65 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS08770 c2c98bbd54df93298ed0996489bfda85 278 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 265 2.2E-108 T 26-04-2017 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 A4V04_RS08770 c2c98bbd54df93298ed0996489bfda85 278 Pfam PF00483 Nucleotidyl transferase 11 267 8.8E-33 T 26-04-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4V04_RS08770 c2c98bbd54df93298ed0996489bfda85 278 Gene3D G3DSA:3.90.550.10 5 272 2.8E-69 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS01740 74c2d3f7c6ae5cf5155c39b56c987b0d 598 SUPERFAMILY SSF55486 52 589 1.83E-56 T 26-04-2017 A4V04_RS01740 74c2d3f7c6ae5cf5155c39b56c987b0d 598 Pfam PF01432 Peptidase family M3 330 574 6.4E-9 T 26-04-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 A4V04_RS06655 a55d1a6320eef6bc46b66fccf68af8c0 330 Pfam PF04392 ABC transporter substrate binding protein 40 323 1.4E-89 T 26-04-2017 IPR007487 ABC transporter, substrate-binding protein A4V04_RS06655 a55d1a6320eef6bc46b66fccf68af8c0 330 SUPERFAMILY SSF53822 56 260 3.99E-15 T 26-04-2017 IPR028082 Periplasmic binding protein-like I A4V04_RS06655 a55d1a6320eef6bc46b66fccf68af8c0 330 Gene3D G3DSA:3.40.50.2300 36 165 1.6E-54 T 26-04-2017 A4V04_RS06655 a55d1a6320eef6bc46b66fccf68af8c0 330 Gene3D G3DSA:3.40.50.2300 166 299 5.3E-50 T 26-04-2017 A4V04_RS06330 0b4e23f0679369f070973fc2eea27802 112 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 99 2.5E-11 T 26-04-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4V04_RS06330 0b4e23f0679369f070973fc2eea27802 112 SUPERFAMILY SSF143011 1 94 1.29E-6 T 26-04-2017 A4V04_RS10255 a7da7c0320b10bbfbacb2fdb65660de1 154 Pfam PF04463 Protein of unknown function (DUF523) 6 144 1.7E-43 T 26-04-2017 IPR007553 Domain of unknown function DUF523 A4V04_RS09935 1cebf1fee8855e91832ee90ad09c4b61 129 Pfam PF03610 PTS system fructose IIA component 4 104 2.7E-13 T 26-04-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A4V04_RS09935 1cebf1fee8855e91832ee90ad09c4b61 129 Gene3D G3DSA:3.40.50.510 3 126 2.2E-25 T 26-04-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A4V04_RS09935 1cebf1fee8855e91832ee90ad09c4b61 129 SUPERFAMILY SSF53062 3 120 5.23E-23 T 26-04-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A4V04_RS08345 5e7d3adf2bd3625c61ffd6efc52377dd 382 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 2 352 1.8E-97 T 26-04-2017 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 A4V04_RS08345 5e7d3adf2bd3625c61ffd6efc52377dd 382 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 352 2.4E-55 T 26-04-2017 IPR005495 Permease LptG/LptF-related GO:0016021 A4V04_RS12830 6d8852b79021ec0db0f8bbc38eaaf442 239 Gene3D G3DSA:3.30.1650.10 31 189 8.5E-20 T 26-04-2017 A4V04_RS12830 6d8852b79021ec0db0f8bbc38eaaf442 239 SUPERFAMILY SSF56821 36 191 3.75E-13 T 26-04-2017 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 A4V04_RS12830 6d8852b79021ec0db0f8bbc38eaaf442 239 Pfam PF03598 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 37 168 4.4E-9 T 26-04-2017 IPR004461 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GO:0006084|GO:0018492 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|KEGG: 00720+2.3.1.169|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 A4V04_RS08280 d2a467ee8b1c9b85cc25440858a9931e 389 SUPERFAMILY SSF111369 57 303 8.24E-80 T 26-04-2017 A4V04_RS08280 d2a467ee8b1c9b85cc25440858a9931e 389 Gene3D G3DSA:2.40.50.100 69 101 8.4E-21 T 26-04-2017 A4V04_RS08280 d2a467ee8b1c9b85cc25440858a9931e 389 Gene3D G3DSA:2.40.50.100 176 210 8.4E-21 T 26-04-2017 A4V04_RS08280 d2a467ee8b1c9b85cc25440858a9931e 389 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 68 296 1.2E-12 T 26-04-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A4V04_RS08280 d2a467ee8b1c9b85cc25440858a9931e 389 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 43 377 1.0E-84 T 26-04-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 A4V04_RS09585 8533e367dfd17a859b092b7aadc59567 129 SUPERFAMILY SSF48695 18 124 2.68E-13 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS09585 8533e367dfd17a859b092b7aadc59567 129 Pfam PF14537 Cytochrome c3 48 123 5.5E-14 T 26-04-2017 A4V04_RS09585 8533e367dfd17a859b092b7aadc59567 129 Gene3D G3DSA:3.90.10.10 26 124 3.7E-12 T 26-04-2017 A4V04_RS07795 3758b621ad5ce4940b6753cce38c3d51 281 PIRSF PIRSF000177 17 260 8.0E-59 T 26-04-2017 IPR004224 Fumarate reductase respiratory complex, transmembrane subunit GO:0006099 A4V04_RS07795 3758b621ad5ce4940b6753cce38c3d51 281 Gene3D G3DSA:1.20.950.10 25 249 1.7E-69 T 26-04-2017 A4V04_RS07795 3758b621ad5ce4940b6753cce38c3d51 281 SUPERFAMILY SSF81343 28 249 8.63E-51 T 26-04-2017 A4V04_RS07795 3758b621ad5ce4940b6753cce38c3d51 281 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 123 228 4.1E-9 T 26-04-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS05080 699ec1499760ab044e31e4c228bc0424 364 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 86 99 - T 26-04-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A4V04_RS05080 699ec1499760ab044e31e4c228bc0424 364 SUPERFAMILY SSF53686 2 361 4.06E-85 T 26-04-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4V04_RS05080 699ec1499760ab044e31e4c228bc0424 364 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 65 342 9.4E-64 T 26-04-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4V04_RS05080 699ec1499760ab044e31e4c228bc0424 364 Gene3D G3DSA:3.40.50.1100 130 361 1.5E-48 T 26-04-2017 A4V04_RS04275 ea22da792a4b871833f90b556e105c5a 207 SUPERFAMILY SSF54626 41 205 8.24E-12 T 26-04-2017 IPR016087 Chalcone isomerase GO:0016872 A4V04_RS04275 ea22da792a4b871833f90b556e105c5a 207 Pfam PF16036 Chalcone isomerase-like 42 205 2.5E-31 T 26-04-2017 IPR016087 Chalcone isomerase GO:0016872 A4V04_RS00665 144351ce15acbc04e45c0db195a5a7a6 438 Pfam PF14403 Circularly permuted ATP-grasp type 2 41 413 6.3E-136 T 26-04-2017 IPR025841 Circularly permuted ATP-grasp type 2 A4V04_RS00665 144351ce15acbc04e45c0db195a5a7a6 438 SUPERFAMILY SSF56059 20 179 2.12E-38 T 26-04-2017 A4V04_RS00665 144351ce15acbc04e45c0db195a5a7a6 438 SUPERFAMILY SSF56059 283 428 2.12E-38 T 26-04-2017 A4V04_RS00665 144351ce15acbc04e45c0db195a5a7a6 438 PIRSF PIRSF005522 1 438 5.3E-161 T 26-04-2017 IPR016450 Uncharacterised conserved protein UCP005522 A4V04_RS05770 870c319cc360f3a8960194bff794326c 357 Gene3D G3DSA:2.40.160.10 21 357 5.8E-67 T 26-04-2017 IPR023614 Porin domain A4V04_RS05770 870c319cc360f3a8960194bff794326c 357 SUPERFAMILY SSF56935 22 357 4.88E-53 T 26-04-2017 A4V04_RS05770 870c319cc360f3a8960194bff794326c 357 Pfam PF13609 Gram-negative porin 8 331 6.9E-37 T 26-04-2017 A4V04_RS10180 13b18b0826d2110239d04961e317f8d7 333 PIRSF PIRSF001220 1 332 5.3E-80 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS10180 13b18b0826d2110239d04961e317f8d7 333 Gene3D G3DSA:3.40.50.40 221 331 9.8E-22 T 26-04-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 A4V04_RS10180 13b18b0826d2110239d04961e317f8d7 333 PRINTS PR00139 Asparaginase/glutaminase family signature 267 285 4.9E-16 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS10180 13b18b0826d2110239d04961e317f8d7 333 PRINTS PR00139 Asparaginase/glutaminase family signature 86 104 4.9E-16 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS10180 13b18b0826d2110239d04961e317f8d7 333 PRINTS PR00139 Asparaginase/glutaminase family signature 6 17 4.9E-16 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS10180 13b18b0826d2110239d04961e317f8d7 333 SMART SM00870 5 326 1.4E-109 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS10180 13b18b0826d2110239d04961e317f8d7 333 Pfam PF00710 Asparaginase, N-terminal 5 197 5.7E-57 T 26-04-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A4V04_RS10180 13b18b0826d2110239d04961e317f8d7 333 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 4 333 2.6E-102 T 26-04-2017 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 A4V04_RS10180 13b18b0826d2110239d04961e317f8d7 333 PIRSF PIRSF500176 2 333 7.3E-70 T 26-04-2017 A4V04_RS10180 13b18b0826d2110239d04961e317f8d7 333 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 87 97 - T 26-04-2017 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A4V04_RS10180 13b18b0826d2110239d04961e317f8d7 333 Gene3D G3DSA:3.40.50.1170 2 213 3.9E-67 T 26-04-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A4V04_RS10180 13b18b0826d2110239d04961e317f8d7 333 SUPERFAMILY SSF53774 4 332 1.05E-84 T 26-04-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4V04_RS08245 ff5db21a75de6fb68946a394bff60c74 405 Pfam PF07690 Major Facilitator Superfamily 18 345 9.4E-30 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS08245 ff5db21a75de6fb68946a394bff60c74 405 SUPERFAMILY SSF103473 6 394 1.7E-52 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS08245 ff5db21a75de6fb68946a394bff60c74 405 Gene3D G3DSA:1.20.1250.20 213 398 2.8E-21 T 26-04-2017 A4V04_RS08245 ff5db21a75de6fb68946a394bff60c74 405 Gene3D G3DSA:1.20.1250.20 12 188 5.1E-19 T 26-04-2017 A4V04_RS07015 ca5e3dd90d63df52a1050a72a0df1067 108 PIRSF PIRSF004555 6 108 4.6E-31 T 26-04-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4V04_RS07015 ca5e3dd90d63df52a1050a72a0df1067 108 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 6 104 3.1E-24 T 26-04-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4V04_RS07015 ca5e3dd90d63df52a1050a72a0df1067 108 SUPERFAMILY SSF82607 14 107 1.12E-27 T 26-04-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4V04_RS07015 ca5e3dd90d63df52a1050a72a0df1067 108 Pfam PF02575 YbaB/EbfC DNA-binding family 14 104 4.7E-29 T 26-04-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4V04_RS07015 ca5e3dd90d63df52a1050a72a0df1067 108 Gene3D G3DSA:3.30.1310.10 4 107 3.1E-38 T 26-04-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4V04_RS07015 ca5e3dd90d63df52a1050a72a0df1067 108 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 8 103 20.224 T 26-04-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4V04_RS04855 30959881a1f77a4114e2fbbeff0f2f20 86 SUPERFAMILY SSF55008 1 66 4.84E-10 T 26-04-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4V04_RS04855 30959881a1f77a4114e2fbbeff0f2f20 86 Gene3D G3DSA:3.30.70.100 3 65 1.5E-8 T 26-04-2017 A4V04_RS04855 30959881a1f77a4114e2fbbeff0f2f20 86 Pfam PF00403 Heavy-metal-associated domain 5 64 1.9E-5 T 26-04-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4V04_RS02465 2106e1d90f86ab8fd04e48e285e52d5d 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 309 6.4E-42 T 26-04-2017 IPR005064 Bordetella uptake gene GO:0030288 A4V04_RS02465 2106e1d90f86ab8fd04e48e285e52d5d 318 SUPERFAMILY SSF53850 117 286 5.72E-12 T 26-04-2017 A4V04_RS02465 2106e1d90f86ab8fd04e48e285e52d5d 318 Gene3D G3DSA:3.40.190.10 128 216 2.4E-4 T 26-04-2017 A4V04_RS02465 2106e1d90f86ab8fd04e48e285e52d5d 318 PIRSF PIRSF017082 1 316 1.3E-74 T 26-04-2017 IPR005064 Bordetella uptake gene GO:0030288 A4V04_RS00940 64edaa9e6cdf2bcfcf5a60343d1b5a55 813 SUPERFAMILY SSF46785 748 811 5.54E-21 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS00940 64edaa9e6cdf2bcfcf5a60343d1b5a55 813 SUPERFAMILY SSF52540 419 712 1.4E-41 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00940 64edaa9e6cdf2bcfcf5a60343d1b5a55 813 Gene3D G3DSA:1.10.10.10 752 799 2.6E-4 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS00940 64edaa9e6cdf2bcfcf5a60343d1b5a55 813 Gene3D G3DSA:3.40.50.300 407 708 2.2E-70 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00940 64edaa9e6cdf2bcfcf5a60343d1b5a55 813 SMART SM00843 748 813 2.1E-35 T 26-04-2017 IPR018541 FtsK gamma domain A4V04_RS00940 64edaa9e6cdf2bcfcf5a60343d1b5a55 813 Pfam PF01580 FtsK/SpoIIIE family 435 643 9.0E-60 T 26-04-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4V04_RS00940 64edaa9e6cdf2bcfcf5a60343d1b5a55 813 SUPERFAMILY SSF103473 35 195 9.29E-7 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS00940 64edaa9e6cdf2bcfcf5a60343d1b5a55 813 Pfam PF09397 Ftsk gamma domain 750 809 6.7E-26 T 26-04-2017 IPR018541 FtsK gamma domain A4V04_RS00940 64edaa9e6cdf2bcfcf5a60343d1b5a55 813 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 34 204 5.9E-32 T 26-04-2017 IPR025199 DNA translocase FtsK, 4TM region A4V04_RS12150 c31dc410d1b63e8c47b2f987ed5b2bf2 301 Pfam PF03916 Polysulphide reductase, NrfD 25 297 7.9E-8 T 26-04-2017 IPR005614 NrfD family A4V04_RS02330 a53ecf06573c35c36f4277d35b7b30c7 99 SUPERFAMILY SSF47413 30 90 7.79E-9 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS02330 a53ecf06573c35c36f4277d35b7b30c7 99 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 5 91 3.2E-33 T 26-04-2017 IPR014057 Addiction module antidote protein, HI1420 A4V04_RS02330 a53ecf06573c35c36f4277d35b7b30c7 99 Gene3D G3DSA:1.10.260.40 34 90 3.4E-6 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS01995 2f12bcedbd2591eb1b0a9911e356c742 444 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 8 442 1.6E-179 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS01995 2f12bcedbd2591eb1b0a9911e356c742 444 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 8 370 1.0E-138 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS01995 2f12bcedbd2591eb1b0a9911e356c742 444 PIRSF PIRSF004539 3 444 4.6E-167 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS01495 6545af1968a298008011fb6953e44eff 301 SUPERFAMILY SSF51735 3 170 6.1E-45 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01495 6545af1968a298008011fb6953e44eff 301 Gene3D G3DSA:1.10.3660.10 221 277 4.4E-4 T 26-04-2017 A4V04_RS01495 6545af1968a298008011fb6953e44eff 301 Pfam PF02153 Prephenate dehydrogenase 19 272 2.6E-69 T 26-04-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 A4V04_RS01495 6545af1968a298008011fb6953e44eff 301 Gene3D G3DSA:3.40.50.720 3 180 2.0E-36 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS01495 6545af1968a298008011fb6953e44eff 301 SUPERFAMILY SSF48179 174 282 9.64E-33 T 26-04-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4V04_RS01730 2b01670d0eb8ad5a3697eca34e22e739 603 SUPERFAMILY SSF55486 137 598 7.08E-38 T 26-04-2017 A4V04_RS11050 3cc08c5d8c74e2476cd4abc4c3bced15 396 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 10 391 2.5E-129 T 26-04-2017 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 A4V04_RS11050 3cc08c5d8c74e2476cd4abc4c3bced15 396 PIRSF PIRSF001434 2 392 7.7E-108 T 26-04-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4V04_RS11050 3cc08c5d8c74e2476cd4abc4c3bced15 396 Gene3D G3DSA:3.90.1150.10 261 391 5.4E-32 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS11050 3cc08c5d8c74e2476cd4abc4c3bced15 396 Gene3D G3DSA:3.40.640.10 8 260 9.5E-68 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS11050 3cc08c5d8c74e2476cd4abc4c3bced15 396 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 389 1.2E-96 T 26-04-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4V04_RS11050 3cc08c5d8c74e2476cd4abc4c3bced15 396 SUPERFAMILY SSF53383 25 390 9.76E-84 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS01110 9c24cc3f18b09b76208c72f341b2f863 280 TIGRFAM TIGR03132 malonate_mdcB: triphosphoribosyl-dephospho-CoA synthase MdcB 11 274 1.1E-86 T 26-04-2017 IPR017555 Triphosphoribosyl-dephospho-CoA synthase GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 A4V04_RS01110 9c24cc3f18b09b76208c72f341b2f863 280 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 12 271 2.4E-69 T 26-04-2017 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 A4V04_RS08220 849c6a19a18cffcc02f02edf63251bc1 307 Pfam PF03466 LysR substrate binding domain 103 299 2.7E-9 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS08220 849c6a19a18cffcc02f02edf63251bc1 307 SUPERFAMILY SSF53850 103 299 2.17E-15 T 26-04-2017 A4V04_RS08220 849c6a19a18cffcc02f02edf63251bc1 307 Gene3D G3DSA:1.10.10.10 7 87 6.1E-23 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS08220 849c6a19a18cffcc02f02edf63251bc1 307 Gene3D G3DSA:3.40.190.10 102 175 7.3E-8 T 26-04-2017 A4V04_RS08220 849c6a19a18cffcc02f02edf63251bc1 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 73 1.2E-14 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS08220 849c6a19a18cffcc02f02edf63251bc1 307 SUPERFAMILY SSF46785 11 85 1.5E-14 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS08220 849c6a19a18cffcc02f02edf63251bc1 307 Gene3D G3DSA:3.40.190.10 176 270 2.7E-12 T 26-04-2017 A4V04_RS08265 bdab5f12c212bb5edc9780da170c0bbe 198 SUPERFAMILY SSF48498 93 163 7.34E-6 T 26-04-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4V04_RS08265 bdab5f12c212bb5edc9780da170c0bbe 198 Gene3D G3DSA:1.10.357.10 7 173 1.3E-18 T 26-04-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4V04_RS08265 bdab5f12c212bb5edc9780da170c0bbe 198 SUPERFAMILY SSF46689 5 73 4.06E-13 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS08265 bdab5f12c212bb5edc9780da170c0bbe 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 58 8.8E-9 T 26-04-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4V04_RS09450 71ec5980d5978b16c497c2974637d3ea 254 Pfam PF02627 Carboxymuconolactone decarboxylase family 20 105 6.1E-19 T 26-04-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4V04_RS09450 71ec5980d5978b16c497c2974637d3ea 254 SUPERFAMILY SSF69118 13 114 1.11E-25 T 26-04-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4V04_RS09450 71ec5980d5978b16c497c2974637d3ea 254 Gene3D G3DSA:2.60.120.10 124 250 6.4E-28 T 26-04-2017 IPR014710 RmlC-like jelly roll fold A4V04_RS09450 71ec5980d5978b16c497c2974637d3ea 254 Gene3D G3DSA:1.20.1290.10 12 116 7.6E-22 T 26-04-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4V04_RS09450 71ec5980d5978b16c497c2974637d3ea 254 SUPERFAMILY SSF51182 125 252 5.34E-22 T 26-04-2017 IPR011051 RmlC-like cupin domain A4V04_RS12860 fdaf51b29262b89c1b351fe98f5b4a18 372 Gene3D G3DSA:2.40.160.10 22 372 1.1E-57 T 26-04-2017 IPR023614 Porin domain A4V04_RS12860 fdaf51b29262b89c1b351fe98f5b4a18 372 Pfam PF13609 Gram-negative porin 7 327 7.5E-36 T 26-04-2017 A4V04_RS12860 fdaf51b29262b89c1b351fe98f5b4a18 372 SUPERFAMILY SSF56935 22 372 6.28E-47 T 26-04-2017 A4V04_RS04390 0a9803de4d10f87a5b9ddadb457dcc46 158 Pfam PF07670 Nucleoside recognition 31 101 1.6E-7 T 26-04-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A4V04_RS07580 d5a7e7c2724fd2f306b8d8863cc83cce 308 Pfam PF03797 Autotransporter beta-domain 70 287 1.0E-13 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS07580 d5a7e7c2724fd2f306b8d8863cc83cce 308 Gene3D G3DSA:2.40.128.130 61 253 2.1E-11 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS07580 d5a7e7c2724fd2f306b8d8863cc83cce 308 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 77 305 1.9E-7 T 26-04-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 A4V04_RS07580 d5a7e7c2724fd2f306b8d8863cc83cce 308 SUPERFAMILY SSF103515 28 282 1.26E-16 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS07580 d5a7e7c2724fd2f306b8d8863cc83cce 308 SMART SM00869 58 297 2.1E-6 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS03950 d0bbbfc7ffddb6199b10ede4983eeba5 435 Pfam PF03553 Na+/H+ antiporter family 149 417 1.1E-24 T 26-04-2017 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A4V04_RS07435 22206987e68d62df5fca4030293474cd 85 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 3 85 1.1E-23 T 26-04-2017 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 A4V04_RS07435 22206987e68d62df5fca4030293474cd 85 Gene3D G3DSA:3.10.20.30 1 85 1.4E-24 T 26-04-2017 IPR012675 Beta-grasp domain A4V04_RS07435 22206987e68d62df5fca4030293474cd 85 SUPERFAMILY SSF54285 1 83 1.47E-18 T 26-04-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A4V04_RS07435 22206987e68d62df5fca4030293474cd 85 Pfam PF02597 ThiS family 5 85 5.1E-16 T 26-04-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 A4V04_RS12060 16faf72e6d34f55a99dc76c86ccf255f 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 132 1.3E-29 T 26-04-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A4V04_RS12060 16faf72e6d34f55a99dc76c86ccf255f 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 42.043 T 26-04-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A4V04_RS12060 16faf72e6d34f55a99dc76c86ccf255f 143 SUPERFAMILY SSF89447 2 130 7.43E-34 T 26-04-2017 A4V04_RS12060 16faf72e6d34f55a99dc76c86ccf255f 143 Pfam PF02381 MraZ protein, putative antitoxin-like 76 139 1.4E-11 T 26-04-2017 IPR020603 MraZ domain A4V04_RS12060 16faf72e6d34f55a99dc76c86ccf255f 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 68 1.3E-8 T 26-04-2017 IPR020603 MraZ domain A4V04_RS12060 16faf72e6d34f55a99dc76c86ccf255f 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 118 1.0E-34 T 26-04-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A4V04_RS05725 6453faeb6600366bd35234ebd38d1e2a 1354 SMART SM00869 1083 1343 4.2E-25 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS05725 6453faeb6600366bd35234ebd38d1e2a 1354 SUPERFAMILY SSF103515 1074 1354 2.35E-29 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS05725 6453faeb6600366bd35234ebd38d1e2a 1354 Gene3D G3DSA:2.40.128.130 1062 1354 3.7E-22 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS05725 6453faeb6600366bd35234ebd38d1e2a 1354 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 920 1354 1.2E-19 T 26-04-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 A4V04_RS09250 6a01316ca517f62b63532f3b1e1dcfd4 292 Gene3D G3DSA:3.40.50.620 47 220 2.3E-15 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS09250 6a01316ca517f62b63532f3b1e1dcfd4 292 SUPERFAMILY SSF52402 46 274 3.75E-49 T 26-04-2017 A4V04_RS09250 6a01316ca517f62b63532f3b1e1dcfd4 292 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 26 287 44.283 T 26-04-2017 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 Reactome: R-HSA-6782315 A4V04_RS09250 6a01316ca517f62b63532f3b1e1dcfd4 292 PIRSF PIRSF004976 10 291 1.9E-66 T 26-04-2017 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 Reactome: R-HSA-6782315 A4V04_RS09250 6a01316ca517f62b63532f3b1e1dcfd4 292 Pfam PF01171 PP-loop family 59 224 6.6E-14 T 26-04-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A4V04_RS02740 b2ded7fa5f77444c3d4328942099ff3a 121 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 1 119 25.66 T 26-04-2017 IPR023006 Uncharacterised protein family UPF0225 A4V04_RS02740 b2ded7fa5f77444c3d4328942099ff3a 121 Gene3D G3DSA:3.10.450.50 2 120 1.5E-39 T 26-04-2017 IPR032710 NTF2-like domain A4V04_RS02740 b2ded7fa5f77444c3d4328942099ff3a 121 SUPERFAMILY SSF54427 22 119 6.13E-30 T 26-04-2017 IPR032710 NTF2-like domain A4V04_RS02740 b2ded7fa5f77444c3d4328942099ff3a 121 Pfam PF02810 SEC-C motif 2 16 7.7E-6 T 26-04-2017 IPR004027 SEC-C motif A4V04_RS00765 d20f5bb1b9c798e18a899f1be8c19c31 252 Gene3D G3DSA:3.90.550.10 1 249 6.3E-71 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS00765 d20f5bb1b9c798e18a899f1be8c19c31 252 Hamap MF_00057 3-deoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 250 39.376 T 26-04-2017 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 A4V04_RS00765 d20f5bb1b9c798e18a899f1be8c19c31 252 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 1 243 5.5E-88 T 26-04-2017 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 A4V04_RS00765 d20f5bb1b9c798e18a899f1be8c19c31 252 Pfam PF02348 Cytidylyltransferase 5 223 1.1E-51 T 26-04-2017 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 A4V04_RS00765 d20f5bb1b9c798e18a899f1be8c19c31 252 SUPERFAMILY SSF53448 3 248 3.67E-53 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS00340 53f646cf9940d49c89aab71c71b26a6b 151 Gene3D G3DSA:3.90.1170.40 3 147 1.1E-57 T 26-04-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS00340 53f646cf9940d49c89aab71c71b26a6b 151 SUPERFAMILY SSF54690 3 147 8.89E-53 T 26-04-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS00340 53f646cf9940d49c89aab71c71b26a6b 151 Pfam PF02391 MoaE protein 5 118 6.8E-38 T 26-04-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4V04_RS07345 bf5a398cdc30ca81d3b1ed51a2f6d6e5 468 SUPERFAMILY SSF48024 15 126 2.22E-31 T 26-04-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A4V04_RS07345 bf5a398cdc30ca81d3b1ed51a2f6d6e5 468 SUPERFAMILY SSF52540 197 447 8.3E-49 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07345 bf5a398cdc30ca81d3b1ed51a2f6d6e5 468 Pfam PF00772 DnaB-like helicase N terminal domain 17 118 4.6E-28 T 26-04-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A4V04_RS07345 bf5a398cdc30ca81d3b1ed51a2f6d6e5 468 Pfam PF03796 DnaB-like helicase C terminal domain 198 454 8.9E-102 T 26-04-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 A4V04_RS07345 bf5a398cdc30ca81d3b1ed51a2f6d6e5 468 Gene3D G3DSA:1.10.860.10 17 119 1.1E-28 T 26-04-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal A4V04_RS07345 bf5a398cdc30ca81d3b1ed51a2f6d6e5 468 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 17 456 1.7E-151 T 26-04-2017 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 A4V04_RS07345 bf5a398cdc30ca81d3b1ed51a2f6d6e5 468 Gene3D G3DSA:3.40.50.300 185 455 6.4E-92 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07805 c8bbeedaf7646e64f54b92cc9d411bbb 424 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 58 416 2.0E-64 T 26-04-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A4V04_RS07805 c8bbeedaf7646e64f54b92cc9d411bbb 424 Pfam PF03606 C4-dicarboxylate anaerobic carrier 56 421 1.1E-21 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS01470 6b1a7469dbb667701d55cf3b3266fbba 95 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 5 81 2.5E-25 T 26-04-2017 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 A4V04_RS01470 6b1a7469dbb667701d55cf3b3266fbba 95 SUPERFAMILY SSF47413 7 91 6.19E-22 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS01470 6b1a7469dbb667701d55cf3b3266fbba 95 Pfam PF01381 Helix-turn-helix 17 63 1.6E-8 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS01470 6b1a7469dbb667701d55cf3b3266fbba 95 SMART SM00530 11 67 1.0E-4 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS01470 6b1a7469dbb667701d55cf3b3266fbba 95 Gene3D G3DSA:1.10.260.40 3 92 3.0E-27 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS08450 6feaf15e57f2a6691a637f8ff24b8b72 194 Pfam PF01169 Uncharacterized protein family UPF0016 109 182 2.1E-24 T 26-04-2017 IPR001727 Gdt1 family GO:0032472 A4V04_RS08450 6feaf15e57f2a6691a637f8ff24b8b72 194 Pfam PF01169 Uncharacterized protein family UPF0016 7 80 1.9E-21 T 26-04-2017 IPR001727 Gdt1 family GO:0032472 A4V04_RS09940 faff5692de2572a54124ef4a671f2dba 118 Pfam PF08895 Domain of unknown function (DUF1840) 3 115 1.4E-30 T 26-04-2017 IPR014991 Protein of unknown function DUF1840 A4V04_RS07750 e238d1e38d05b67d759ee0c1c7933ed6 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 218 3.0E-22 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS07750 e238d1e38d05b67d759ee0c1c7933ed6 226 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 12 219 1.7E-71 T 26-04-2017 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 A4V04_RS07750 e238d1e38d05b67d759ee0c1c7933ed6 226 Gene3D G3DSA:1.10.3720.10 11 221 1.8E-39 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS07750 e238d1e38d05b67d759ee0c1c7933ed6 226 SUPERFAMILY SSF161098 9 217 9.81E-45 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS02875 122c5ebe2d3f51adababd7deffd67409 328 SUPERFAMILY SSF53901 7 328 1.83E-68 T 26-04-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4V04_RS02875 122c5ebe2d3f51adababd7deffd67409 328 Gene3D G3DSA:3.40.47.10 170 327 1.2E-49 T 26-04-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4V04_RS02875 122c5ebe2d3f51adababd7deffd67409 328 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 7 327 2.0E-120 T 26-04-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4V04_RS02875 122c5ebe2d3f51adababd7deffd67409 328 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 5 328 66.053 T 26-04-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4V04_RS02875 122c5ebe2d3f51adababd7deffd67409 328 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 239 328 2.7E-32 T 26-04-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4V04_RS02875 122c5ebe2d3f51adababd7deffd67409 328 Gene3D G3DSA:3.40.47.10 8 169 1.8E-66 T 26-04-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4V04_RS02875 122c5ebe2d3f51adababd7deffd67409 328 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 115 192 1.9E-33 T 26-04-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4V04_RS09630 bd6af64829a5fc37d7ddfc397380e093 466 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 4 445 7.6E-112 T 26-04-2017 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 A4V04_RS09630 bd6af64829a5fc37d7ddfc397380e093 466 Pfam PF03553 Na+/H+ antiporter family 147 440 1.1E-34 T 26-04-2017 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A4V04_RS10005 95b56454c0b0d1819b86251562c95192 440 SMART SM00116 223 272 2.4 T 26-04-2017 IPR000644 CBS domain A4V04_RS10005 95b56454c0b0d1819b86251562c95192 440 SMART SM00116 287 335 1.3 T 26-04-2017 IPR000644 CBS domain A4V04_RS10005 95b56454c0b0d1819b86251562c95192 440 Gene3D G3DSA:3.10.580.10 201 341 3.2E-15 T 26-04-2017 A4V04_RS10005 95b56454c0b0d1819b86251562c95192 440 SUPERFAMILY SSF56176 346 434 5.18E-25 T 26-04-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4V04_RS10005 95b56454c0b0d1819b86251562c95192 440 SUPERFAMILY SSF54631 203 337 3.3E-23 T 26-04-2017 A4V04_RS10005 95b56454c0b0d1819b86251562c95192 440 Pfam PF00571 CBS domain 287 334 3.4E-5 T 26-04-2017 IPR000644 CBS domain A4V04_RS10005 95b56454c0b0d1819b86251562c95192 440 SMART SM01091 348 428 6.0E-31 T 26-04-2017 IPR005170 Transporter-associated domain A4V04_RS10005 95b56454c0b0d1819b86251562c95192 440 Pfam PF01595 Domain of unknown function DUF21 8 199 1.0E-37 T 26-04-2017 IPR002550 Domain of unknown function DUF21 A4V04_RS10005 95b56454c0b0d1819b86251562c95192 440 Gene3D G3DSA:3.30.465.10 343 434 2.5E-28 T 26-04-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4V04_RS10005 95b56454c0b0d1819b86251562c95192 440 Pfam PF03471 Transporter associated domain 349 427 1.9E-22 T 26-04-2017 IPR005170 Transporter-associated domain A4V04_RS10635 89b0a6fb3a40e4fc0df74b25960663aa 266 SUPERFAMILY SSF52540 1 255 3.49E-60 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10635 89b0a6fb3a40e4fc0df74b25960663aa 266 Pfam PF13614 AAA domain 3 177 4.3E-59 T 26-04-2017 IPR025669 AAA domain A4V04_RS10635 89b0a6fb3a40e4fc0df74b25960663aa 266 Gene3D G3DSA:3.40.50.300 3 264 4.2E-66 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08590 c033dc4e474bee0d87788dd029c6df9a 404 Pfam PF00654 Voltage gated chloride channel 31 373 1.1E-73 T 26-04-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4V04_RS08590 c033dc4e474bee0d87788dd029c6df9a 404 PRINTS PR00762 Chloride channel signature 44 61 1.7E-17 T 26-04-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4V04_RS08590 c033dc4e474bee0d87788dd029c6df9a 404 PRINTS PR00762 Chloride channel signature 323 339 1.7E-17 T 26-04-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4V04_RS08590 c033dc4e474bee0d87788dd029c6df9a 404 PRINTS PR00762 Chloride channel signature 124 143 1.7E-17 T 26-04-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4V04_RS08590 c033dc4e474bee0d87788dd029c6df9a 404 PRINTS PR00762 Chloride channel signature 290 310 1.7E-17 T 26-04-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4V04_RS08590 c033dc4e474bee0d87788dd029c6df9a 404 SUPERFAMILY SSF81340 12 387 2.88E-77 T 26-04-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 A4V04_RS08590 c033dc4e474bee0d87788dd029c6df9a 404 Gene3D G3DSA:1.10.3080.10 18 385 1.1E-69 T 26-04-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 A4V04_RS00675 48553bcd6dda220541d2328c79d1d166 256 Gene3D G3DSA:3.90.260.10 153 217 1.8E-8 T 26-04-2017 IPR002931 Transglutaminase-like A4V04_RS00675 48553bcd6dda220541d2328c79d1d166 256 SUPERFAMILY SSF54001 90 233 1.54E-29 T 26-04-2017 A4V04_RS00675 48553bcd6dda220541d2328c79d1d166 256 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 9 81 1.7E-7 T 26-04-2017 IPR013589 Bacterial transglutaminase-like, N-terminal A4V04_RS00675 48553bcd6dda220541d2328c79d1d166 256 SMART SM00460 154 212 4.6E-14 T 26-04-2017 IPR002931 Transglutaminase-like A4V04_RS00675 48553bcd6dda220541d2328c79d1d166 256 Pfam PF01841 Transglutaminase-like superfamily 125 210 2.5E-16 T 26-04-2017 IPR002931 Transglutaminase-like A4V04_RS06810 dc49e917ee3f3a60e4b60ead1b0be103 106 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 74 3.6E-19 T 26-04-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A4V04_RS06810 dc49e917ee3f3a60e4b60ead1b0be103 106 SUPERFAMILY SSF159127 1 75 1.07E-17 T 26-04-2017 A4V04_RS06810 dc49e917ee3f3a60e4b60ead1b0be103 106 Pfam PF01455 HupF/HypC family 1 66 4.5E-16 T 26-04-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A4V04_RS06810 dc49e917ee3f3a60e4b60ead1b0be103 106 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 18 34 8.5E-10 T 26-04-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A4V04_RS06810 dc49e917ee3f3a60e4b60ead1b0be103 106 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 8.5E-10 T 26-04-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A4V04_RS06810 dc49e917ee3f3a60e4b60ead1b0be103 106 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 39 55 8.5E-10 T 26-04-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A4V04_RS06810 dc49e917ee3f3a60e4b60ead1b0be103 106 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 60 72 8.5E-10 T 26-04-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A4V04_RS10215 18372cc508463d4f3d0e6b001df55f08 174 Pfam PF03550 Outer membrane lipoprotein LolB 33 139 3.6E-12 T 26-04-2017 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 A4V04_RS10215 18372cc508463d4f3d0e6b001df55f08 174 SUPERFAMILY SSF89392 18 129 5.49E-12 T 26-04-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX A4V04_RS10215 18372cc508463d4f3d0e6b001df55f08 174 Gene3D G3DSA:2.50.20.10 12 151 2.7E-15 T 26-04-2017 A4V04_RS09520 76c00f6414426c123b2108d5284b38b1 125 Gene3D G3DSA:1.10.10.10 7 119 1.1E-44 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09520 76c00f6414426c123b2108d5284b38b1 125 SUPERFAMILY SSF46785 9 119 4.65E-35 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09520 76c00f6414426c123b2108d5284b38b1 125 Pfam PF01638 HxlR-like helix-turn-helix 23 111 4.6E-30 T 26-04-2017 IPR002577 Helix-turn-helix, HxlR type A4V04_RS04295 06ed3a09b266b513c333c67cf07ddad5 296 SMART SM00671 77 112 4.2E-4 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04295 06ed3a09b266b513c333c67cf07ddad5 296 SMART SM00671 41 76 0.26 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04295 06ed3a09b266b513c333c67cf07ddad5 296 SMART SM00671 216 251 0.056 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04295 06ed3a09b266b513c333c67cf07ddad5 296 SMART SM00671 113 148 3.1E-4 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04295 06ed3a09b266b513c333c67cf07ddad5 296 Gene3D G3DSA:1.25.40.10 22 265 9.2E-35 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS04295 06ed3a09b266b513c333c67cf07ddad5 296 Pfam PF08238 Sel1 repeat 79 111 0.0049 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04295 06ed3a09b266b513c333c67cf07ddad5 296 Pfam PF08238 Sel1 repeat 183 215 12.0 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04295 06ed3a09b266b513c333c67cf07ddad5 296 Pfam PF08238 Sel1 repeat 46 76 0.0053 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04295 06ed3a09b266b513c333c67cf07ddad5 296 Pfam PF08238 Sel1 repeat 113 146 0.004 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04295 06ed3a09b266b513c333c67cf07ddad5 296 Pfam PF08238 Sel1 repeat 217 251 0.5 T 26-04-2017 IPR006597 Sel1-like repeat A4V04_RS04295 06ed3a09b266b513c333c67cf07ddad5 296 SUPERFAMILY SSF81901 30 258 4.27E-29 T 26-04-2017 A4V04_RS12910 e45051b4a7502a97f3b60e15497b260e 374 Gene3D G3DSA:3.40.50.1980 174 349 4.3E-27 T 26-04-2017 A4V04_RS12910 e45051b4a7502a97f3b60e15497b260e 374 Pfam PF01497 Periplasmic binding protein 59 316 4.3E-27 T 26-04-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A4V04_RS12910 e45051b4a7502a97f3b60e15497b260e 374 SUPERFAMILY SSF53807 28 356 5.49E-43 T 26-04-2017 A4V04_RS12910 e45051b4a7502a97f3b60e15497b260e 374 Gene3D G3DSA:3.40.50.1980 87 173 6.2E-14 T 26-04-2017 A4V04_RS08100 9495c3ca91abc7e29a55f2845acd474a 242 SUPERFAMILY SSF55120 2 230 4.86E-41 T 26-04-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS08100 9495c3ca91abc7e29a55f2845acd474a 242 Pfam PF00849 RNA pseudouridylate synthase 12 164 4.9E-20 T 26-04-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4V04_RS07020 5753bc9372079e961022d82e65bd4b7f 665 SUPERFAMILY SSF48019 248 367 7.14E-28 T 26-04-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A4V04_RS07020 5753bc9372079e961022d82e65bd4b7f 665 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 238 366 5.9E-25 T 26-04-2017 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 A4V04_RS07020 5753bc9372079e961022d82e65bd4b7f 665 Gene3D G3DSA:3.40.50.300 15 171 4.5E-61 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07020 5753bc9372079e961022d82e65bd4b7f 665 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 360 1.9E-122 T 26-04-2017 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 A4V04_RS07020 5753bc9372079e961022d82e65bd4b7f 665 Gene3D G3DSA:1.20.272.10 248 365 2.7E-37 T 26-04-2017 A4V04_RS07020 5753bc9372079e961022d82e65bd4b7f 665 SMART SM00382 37 183 3.2E-6 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS07020 5753bc9372079e961022d82e65bd4b7f 665 SUPERFAMILY SSF52540 31 229 2.16E-50 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07020 5753bc9372079e961022d82e65bd4b7f 665 Pfam PF13177 DNA polymerase III, delta subunit 20 183 1.2E-37 T 26-04-2017 A4V04_RS07020 5753bc9372079e961022d82e65bd4b7f 665 Gene3D G3DSA:1.10.8.60 172 247 1.8E-28 T 26-04-2017 A4V04_RS09820 5d2a11752dd905cdc8198d604520435d 482 SUPERFAMILY SSF89095 301 406 8.76E-28 T 26-04-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 A4V04_RS09820 5d2a11752dd905cdc8198d604520435d 482 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 480 3.9E-173 T 26-04-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 A4V04_RS09820 5d2a11752dd905cdc8198d604520435d 482 SMART SM00845 332 480 6.0E-70 T 26-04-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 A4V04_RS09820 5d2a11752dd905cdc8198d604520435d 482 Gene3D G3DSA:1.10.10.410 424 481 2.0E-5 T 26-04-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A4V04_RS09820 5d2a11752dd905cdc8198d604520435d 482 SUPERFAMILY SSF55931 4 300 1.44E-117 T 26-04-2017 A4V04_RS09820 5d2a11752dd905cdc8198d604520435d 482 Pfam PF02934 GatB/GatE catalytic domain 5 293 2.5E-110 T 26-04-2017 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 A4V04_RS09820 5d2a11752dd905cdc8198d604520435d 482 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 148 162 - T 26-04-2017 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 A4V04_RS09820 5d2a11752dd905cdc8198d604520435d 482 Pfam PF02637 GatB domain 333 480 4.2E-50 T 26-04-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 A4V04_RS09820 5d2a11752dd905cdc8198d604520435d 482 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 481 37.431 T 26-04-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 A4V04_RS09490 525d941dd2500c511c3a1137bb69b604 363 Pfam PF02653 Branched-chain amino acid transport system / permease component 68 340 2.5E-38 T 26-04-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A4V04_RS01935 14456c315cdef92522538da6faac6937 430 SUPERFAMILY SSF53756 174 424 3.14E-14 T 26-04-2017 A4V04_RS01935 14456c315cdef92522538da6faac6937 430 Pfam PF13692 Glycosyl transferases group 1 278 391 4.8E-10 T 26-04-2017 A4V04_RS11750 0fcf29a2a3943e1086e4ee9d03ff3431 1230 SUPERFAMILY SSF103515 920 1230 1.31E-27 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS11750 0fcf29a2a3943e1086e4ee9d03ff3431 1230 SMART SM00869 942 1217 6.6E-14 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS11750 0fcf29a2a3943e1086e4ee9d03ff3431 1230 Pfam PF03797 Autotransporter beta-domain 944 1197 1.1E-26 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS11750 0fcf29a2a3943e1086e4ee9d03ff3431 1230 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 1002 1230 2.4E-26 T 26-04-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 A4V04_RS11750 0fcf29a2a3943e1086e4ee9d03ff3431 1230 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 899 976 2.2E-9 T 26-04-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 A4V04_RS11750 0fcf29a2a3943e1086e4ee9d03ff3431 1230 Gene3D G3DSA:2.40.128.130 900 1230 7.3E-54 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS01680 bbeb7f3393cd14f12307729be0c051d8 412 Gene3D G3DSA:3.40.50.300 16 156 6.8E-16 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01680 bbeb7f3393cd14f12307729be0c051d8 412 Pfam PF13635 Domain of unknown function (DUF4143) 227 360 2.7E-11 T 26-04-2017 IPR025420 Domain of unknown function DUF4143 A4V04_RS01680 bbeb7f3393cd14f12307729be0c051d8 412 SUPERFAMILY SSF52540 12 213 2.32E-25 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01680 bbeb7f3393cd14f12307729be0c051d8 412 Pfam PF13173 AAA domain 34 162 9.1E-39 T 26-04-2017 A4V04_RS01525 b6f430477665a9dc6cd5ab6ff0be0c58 314 SUPERFAMILY SSF53850 96 280 4.65E-19 T 26-04-2017 A4V04_RS01525 b6f430477665a9dc6cd5ab6ff0be0c58 314 Pfam PF03466 LysR substrate binding domain 95 281 1.8E-15 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS01525 b6f430477665a9dc6cd5ab6ff0be0c58 314 Gene3D G3DSA:3.40.190.10 100 225 3.6E-8 T 26-04-2017 A4V04_RS01525 b6f430477665a9dc6cd5ab6ff0be0c58 314 Gene3D G3DSA:1.10.10.10 10 89 1.7E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01525 b6f430477665a9dc6cd5ab6ff0be0c58 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 67 4.3E-15 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS01525 b6f430477665a9dc6cd5ab6ff0be0c58 314 SUPERFAMILY SSF46785 12 88 1.12E-15 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS06625 ff85718a545b026fb33b24652c013780 268 Gene3D G3DSA:1.10.3290.10 6 262 1.1E-44 T 26-04-2017 IPR003812 Fido domain A4V04_RS06625 ff85718a545b026fb33b24652c013780 268 SUPERFAMILY SSF140931 65 258 4.97E-27 T 26-04-2017 IPR003812 Fido domain A4V04_RS06625 ff85718a545b026fb33b24652c013780 268 Pfam PF02661 Fic/DOC family 90 203 8.7E-14 T 26-04-2017 IPR003812 Fido domain A4V04_RS03110 d7c1e74c3c922864a7153ae1fff7ac3c 111 Pfam PF14537 Cytochrome c3 30 105 8.1E-18 T 26-04-2017 A4V04_RS03110 d7c1e74c3c922864a7153ae1fff7ac3c 111 Gene3D G3DSA:3.90.10.10 22 106 6.9E-12 T 26-04-2017 A4V04_RS03110 d7c1e74c3c922864a7153ae1fff7ac3c 111 SUPERFAMILY SSF48695 26 105 2.58E-14 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS03195 92966a8c42238613a5fe0cccf90dc675 285 SUPERFAMILY SSF51569 2 276 6.5E-100 T 26-04-2017 A4V04_RS03195 92966a8c42238613a5fe0cccf90dc675 285 Gene3D G3DSA:3.20.20.70 11 276 2.5E-112 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS03195 92966a8c42238613a5fe0cccf90dc675 285 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 8 276 52.614 T 26-04-2017 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A4V04_RS03195 92966a8c42238613a5fe0cccf90dc675 285 Pfam PF00793 DAHP synthetase I family 7 273 6.1E-65 T 26-04-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A4V04_RS03195 92966a8c42238613a5fe0cccf90dc675 285 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 13 274 3.6E-122 T 26-04-2017 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A4V04_RS06540 17212009b2f703e42142727ecf6f5778 81 Pfam PF04221 RelB antitoxin 3 68 9.7E-10 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS00030 54f8bdda84b28fca93dc0130ccfe716b 98 SUPERFAMILY SSF47413 28 97 3.03E-8 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS00030 54f8bdda84b28fca93dc0130ccfe716b 98 Gene3D G3DSA:1.10.260.40 41 95 5.8E-12 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS00030 54f8bdda84b28fca93dc0130ccfe716b 98 SMART SM00530 38 96 1.7E-4 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS00030 54f8bdda84b28fca93dc0130ccfe716b 98 Pfam PF01381 Helix-turn-helix 41 94 4.7E-7 T 26-04-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4V04_RS12895 75da553752850728fd4cd6b61cc4b5a9 236 SUPERFAMILY SSF53597 2 233 2.35E-27 T 26-04-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4V04_RS12895 75da553752850728fd4cd6b61cc4b5a9 236 Pfam PF01872 RibD C-terminal domain 2 228 4.5E-18 T 26-04-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4V04_RS12895 75da553752850728fd4cd6b61cc4b5a9 236 Gene3D G3DSA:3.40.430.10 2 234 3.0E-28 T 26-04-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4V04_RS02970 e5d74c7e0f54022404ed2b185dd766a5 134 SUPERFAMILY SSF46785 1 79 7.62E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02970 e5d74c7e0f54022404ed2b185dd766a5 134 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 59 2.4E-15 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS02970 e5d74c7e0f54022404ed2b185dd766a5 134 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-5 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS02970 e5d74c7e0f54022404ed2b185dd766a5 134 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-5 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS02970 e5d74c7e0f54022404ed2b185dd766a5 134 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-5 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS02970 e5d74c7e0f54022404ed2b185dd766a5 134 Gene3D G3DSA:1.10.10.10 1 79 1.0E-18 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS03965 329c41a63f12d534aa9a8cd16ae2bea1 217 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 16 212 2.0E-74 T 26-04-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS03965 329c41a63f12d534aa9a8cd16ae2bea1 217 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 20 211 3.3E-81 T 26-04-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS03965 329c41a63f12d534aa9a8cd16ae2bea1 217 Gene3D G3DSA:3.90.870.10 13 215 5.5E-92 T 26-04-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain A4V04_RS03965 329c41a63f12d534aa9a8cd16ae2bea1 217 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 14 216 40.863 T 26-04-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4V04_RS03965 329c41a63f12d534aa9a8cd16ae2bea1 217 SUPERFAMILY SSF55821 14 214 6.18E-82 T 26-04-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain A4V04_RS06590 f97f700816e435499936aeb0a15eb28b 244 Gene3D G3DSA:1.10.443.10 59 238 2.5E-35 T 26-04-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS06590 f97f700816e435499936aeb0a15eb28b 244 SUPERFAMILY SSF56349 57 240 2.35E-37 T 26-04-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4V04_RS06590 f97f700816e435499936aeb0a15eb28b 244 Pfam PF00589 Phage integrase family 59 228 1.5E-26 T 26-04-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS03755 67f6237f18f725c718e5e1a8b69f6e80 368 Gene3D G3DSA:3.40.50.2000 150 315 6.1E-20 T 26-04-2017 A4V04_RS03755 67f6237f18f725c718e5e1a8b69f6e80 368 Pfam PF13439 Glycosyltransferase Family 4 14 165 2.8E-15 T 26-04-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4V04_RS03755 67f6237f18f725c718e5e1a8b69f6e80 368 Pfam PF00534 Glycosyl transferases group 1 179 317 7.6E-22 T 26-04-2017 IPR001296 Glycosyl transferase, family 1 A4V04_RS03755 67f6237f18f725c718e5e1a8b69f6e80 368 SUPERFAMILY SSF53756 2 344 4.44E-52 T 26-04-2017 A4V04_RS00620 417abf4019ae8336afc12f2c60cc53fe 143 SUPERFAMILY SSF47413 84 140 2.93E-5 T 26-04-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4V04_RS04930 dfd109f84bcf2e200739a2a26ce4b98e 179 Pfam PF04390 Lipopolysaccharide-assembly 17 163 2.7E-15 T 26-04-2017 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 A4V04_RS04930 dfd109f84bcf2e200739a2a26ce4b98e 179 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 10 168 19.138 T 26-04-2017 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 A4V04_RS04930 dfd109f84bcf2e200739a2a26ce4b98e 179 Gene3D G3DSA:3.30.160.150 25 175 1.1E-36 T 26-04-2017 A4V04_RS12925 88818fb8d5273a613a2d22b80b6ba4fc 237 SUPERFAMILY SSF53335 5 214 3.35E-41 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS12925 88818fb8d5273a613a2d22b80b6ba4fc 237 Pfam PF08241 Methyltransferase domain 48 144 6.6E-26 T 26-04-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A4V04_RS12925 88818fb8d5273a613a2d22b80b6ba4fc 237 Gene3D G3DSA:3.40.50.150 8 214 3.8E-41 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS04025 68a8f7ba561cdbd8f8748fe283e6ba49 664 Gene3D G3DSA:1.20.950.20 67 247 3.0E-15 T 26-04-2017 A4V04_RS04025 68a8f7ba561cdbd8f8748fe283e6ba49 664 Pfam PF02665 Nitrate reductase gamma subunit 86 249 2.8E-6 T 26-04-2017 IPR023234 NarG-like domain A4V04_RS04025 68a8f7ba561cdbd8f8748fe283e6ba49 664 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 289 300 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS04025 68a8f7ba561cdbd8f8748fe283e6ba49 664 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 345 356 - T 26-04-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4V04_RS04025 68a8f7ba561cdbd8f8748fe283e6ba49 664 Pfam PF02754 Cysteine-rich domain 550 638 6.9E-11 T 26-04-2017 IPR004017 Cysteine-rich domain A4V04_RS04025 68a8f7ba561cdbd8f8748fe283e6ba49 664 Pfam PF02754 Cysteine-rich domain 425 509 4.2E-13 T 26-04-2017 IPR004017 Cysteine-rich domain A4V04_RS04025 68a8f7ba561cdbd8f8748fe283e6ba49 664 SUPERFAMILY SSF103501 15 255 1.19E-26 T 26-04-2017 IPR023234 NarG-like domain A4V04_RS04025 68a8f7ba561cdbd8f8748fe283e6ba49 664 Gene3D G3DSA:1.10.1060.10 265 376 3.9E-26 T 26-04-2017 A4V04_RS04025 68a8f7ba561cdbd8f8748fe283e6ba49 664 Pfam PF13237 4Fe-4S dicluster domain 284 356 1.8E-11 T 26-04-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4V04_RS04025 68a8f7ba561cdbd8f8748fe283e6ba49 664 SUPERFAMILY SSF46548 274 374 1.5E-20 T 26-04-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 A4V04_RS01830 24058caff5232eb7ab907eaafc88542e 197 TIGRFAM TIGR02761 TraE_TIGR: type IV conjugative transfer system protein TraE 1 180 3.2E-37 T 26-04-2017 IPR007973 Pilus assembly TraE GO:0000746 A4V04_RS01830 24058caff5232eb7ab907eaafc88542e 197 Pfam PF05309 TraE protein 1 182 1.8E-49 T 26-04-2017 IPR007973 Pilus assembly TraE GO:0000746 A4V04_RS13190 a63f6ee2812cd1cb771a742410bd9c1c 435 Pfam PF13520 Amino acid permease 11 417 5.7E-45 T 26-04-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4V04_RS13190 a63f6ee2812cd1cb771a742410bd9c1c 435 PIRSF PIRSF006060 1 433 6.4E-47 T 26-04-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4V04_RS13190 a63f6ee2812cd1cb771a742410bd9c1c 435 TIGRFAM TIGR04299 antiport_PotE: putrescine-ornithine antiporter 5 430 2.4E-203 T 26-04-2017 IPR027566 Putrescine-ornithine antiporter GO:0015496|GO:0015822|GO:0015847 A4V04_RS02390 887be1ce7aa24e740304b079f72ca858 495 SUPERFAMILY SSF51905 436 493 6.06E-62 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02390 887be1ce7aa24e740304b079f72ca858 495 SUPERFAMILY SSF51905 37 296 6.06E-62 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02390 887be1ce7aa24e740304b079f72ca858 495 Pfam PF00890 FAD binding domain 47 476 3.2E-78 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02390 887be1ce7aa24e740304b079f72ca858 495 Gene3D G3DSA:3.90.700.10 303 424 1.6E-30 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02390 887be1ce7aa24e740304b079f72ca858 495 SUPERFAMILY SSF56425 303 437 2.09E-31 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02390 887be1ce7aa24e740304b079f72ca858 495 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 46 488 2.7E-119 T 26-04-2017 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 A4V04_RS02390 887be1ce7aa24e740304b079f72ca858 495 Gene3D G3DSA:3.50.50.60 433 493 8.9E-95 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02390 887be1ce7aa24e740304b079f72ca858 495 Gene3D G3DSA:3.50.50.60 32 279 8.9E-95 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS02390 887be1ce7aa24e740304b079f72ca858 495 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 441 463 1.6E-6 T 26-04-2017 A4V04_RS02390 887be1ce7aa24e740304b079f72ca858 495 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 47 66 1.6E-6 T 26-04-2017 A4V04_RS04400 507a528f0a30621588649ec37aa23829 342 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 66 2.2E-9 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS04400 507a528f0a30621588649ec37aa23829 342 Gene3D G3DSA:1.10.10.10 11 83 7.8E-12 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04400 507a528f0a30621588649ec37aa23829 342 Gene3D G3DSA:3.40.190.10 128 203 1.8E-4 T 26-04-2017 A4V04_RS04400 507a528f0a30621588649ec37aa23829 342 SUPERFAMILY SSF53850 121 311 1.09E-18 T 26-04-2017 A4V04_RS04400 507a528f0a30621588649ec37aa23829 342 Pfam PF03466 LysR substrate binding domain 126 304 2.7E-12 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS04400 507a528f0a30621588649ec37aa23829 342 SUPERFAMILY SSF46785 10 82 3.27E-12 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09865 923b4933a7cb089b492707152be17a05 359 Gene3D G3DSA:3.90.10.10 234 238 5.9E-9 T 26-04-2017 A4V04_RS09865 923b4933a7cb089b492707152be17a05 359 Gene3D G3DSA:3.90.10.10 79 152 5.9E-9 T 26-04-2017 A4V04_RS09865 923b4933a7cb089b492707152be17a05 359 Gene3D G3DSA:1.20.140.10 239 347 1.5E-5 T 26-04-2017 A4V04_RS09865 923b4933a7cb089b492707152be17a05 359 SUPERFAMILY SSF48695 214 345 4.19E-16 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS09865 923b4933a7cb089b492707152be17a05 359 SUPERFAMILY SSF48695 85 180 4.19E-16 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS10985 f7fba99c165f3807ae8af9e55cd1b901 417 SUPERFAMILY SSF103473 6 403 2.22E-43 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS10985 f7fba99c165f3807ae8af9e55cd1b901 417 Pfam PF07690 Major Facilitator Superfamily 27 367 3.7E-27 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS10985 f7fba99c165f3807ae8af9e55cd1b901 417 Gene3D G3DSA:1.20.1250.20 223 406 1.1E-15 T 26-04-2017 A4V04_RS10985 f7fba99c165f3807ae8af9e55cd1b901 417 Gene3D G3DSA:1.20.1250.20 6 189 3.4E-14 T 26-04-2017 A4V04_RS05270 f63f2a85062c4805a22a723e12174245 108 Pfam PF04205 FMN-binding domain 32 104 2.4E-13 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS05270 f63f2a85062c4805a22a723e12174245 108 SMART SM00900 32 107 3.1E-13 T 26-04-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 A4V04_RS10605 5c02ed8688c49b02408d2b12bf56ef6d 555 SUPERFAMILY SSF161098 303 533 9.94E-38 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS10605 5c02ed8688c49b02408d2b12bf56ef6d 555 Gene3D G3DSA:1.10.3720.10 296 534 2.5E-36 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS10605 5c02ed8688c49b02408d2b12bf56ef6d 555 Gene3D G3DSA:1.10.3720.10 16 272 6.2E-39 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS10605 5c02ed8688c49b02408d2b12bf56ef6d 555 SUPERFAMILY SSF161098 12 268 1.96E-43 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS10605 5c02ed8688c49b02408d2b12bf56ef6d 555 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 366 541 1.2E-12 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS10605 5c02ed8688c49b02408d2b12bf56ef6d 555 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 267 1.7E-11 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS10040 9b6cdecc660733b54422a5c3633703e0 368 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 167 353 6.5E-20 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS10040 9b6cdecc660733b54422a5c3633703e0 368 Gene3D G3DSA:1.10.3720.10 144 354 5.2E-43 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS10040 9b6cdecc660733b54422a5c3633703e0 368 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 148 244 2.7E-20 T 26-04-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A4V04_RS10040 9b6cdecc660733b54422a5c3633703e0 368 SUPERFAMILY SSF161098 146 353 3.14E-37 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS08545 9faa08fe2f2992b28e820acc9dee0d52 158 Pfam PF01967 MoaC family 15 150 2.0E-52 T 26-04-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A4V04_RS08545 9faa08fe2f2992b28e820acc9dee0d52 158 Gene3D G3DSA:3.30.70.640 3 156 1.3E-65 T 26-04-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A4V04_RS08545 9faa08fe2f2992b28e820acc9dee0d52 158 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 158 34.956 T 26-04-2017 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type Reactome: R-HSA-947581 A4V04_RS08545 9faa08fe2f2992b28e820acc9dee0d52 158 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 152 4.4E-59 T 26-04-2017 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 A4V04_RS08545 9faa08fe2f2992b28e820acc9dee0d52 158 SUPERFAMILY SSF55040 11 155 1.31E-59 T 26-04-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A4V04_RS01020 b742eb85cf4218da24ea9364ef7ec620 186 Pfam PF00881 Nitroreductase family 12 165 1.1E-9 T 26-04-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4V04_RS01020 b742eb85cf4218da24ea9364ef7ec620 186 Gene3D G3DSA:3.40.109.10 6 183 3.4E-20 T 26-04-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4V04_RS01020 b742eb85cf4218da24ea9364ef7ec620 186 SUPERFAMILY SSF55469 5 183 1.96E-16 T 26-04-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4V04_RS12125 2304a3ea992d2afd6e16d52131b8c019 456 Pfam PF03606 C4-dicarboxylate anaerobic carrier 8 450 3.4E-73 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS12125 2304a3ea992d2afd6e16d52131b8c019 456 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 58 445 1.6E-94 T 26-04-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A4V04_RS10420 abc3d16f1e0c073e6f0c71f21f0c6d6f 320 TIGRFAM TIGR00510 lipA: lipoyl synthase 25 307 6.2E-120 T 26-04-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4V04_RS10420 abc3d16f1e0c073e6f0c71f21f0c6d6f 320 Gene3D G3DSA:3.20.20.70 42 310 2.9E-65 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS10420 abc3d16f1e0c073e6f0c71f21f0c6d6f 320 Hamap MF_00206 Lipoyl synthase [lipA]. 1 315 128.348 T 26-04-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4V04_RS10420 abc3d16f1e0c073e6f0c71f21f0c6d6f 320 PIRSF PIRSF005963 3 318 1.2E-121 T 26-04-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4V04_RS10420 abc3d16f1e0c073e6f0c71f21f0c6d6f 320 SUPERFAMILY SSF102114 43 304 9.42E-60 T 26-04-2017 A4V04_RS10420 abc3d16f1e0c073e6f0c71f21f0c6d6f 320 SMART SM00729 77 285 5.5E-17 T 26-04-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4V04_RS10420 abc3d16f1e0c073e6f0c71f21f0c6d6f 320 Pfam PF04055 Radical SAM superfamily 85 243 2.7E-17 T 26-04-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 A4V04_RS07860 75ad2cb5359d1a74172d97ff2b3e5ad3 222 Pfam PF00731 AIR carboxylase 88 214 8.4E-16 T 26-04-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4V04_RS07860 75ad2cb5359d1a74172d97ff2b3e5ad3 222 SMART SM01001 87 219 3.7E-21 T 26-04-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4V04_RS07860 75ad2cb5359d1a74172d97ff2b3e5ad3 222 Gene3D G3DSA:3.40.50.7700 87 214 3.5E-21 T 26-04-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4V04_RS07860 75ad2cb5359d1a74172d97ff2b3e5ad3 222 SUPERFAMILY SSF52255 87 214 2.88E-23 T 26-04-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4V04_RS05280 398ec1467fb46da40265bdfd58f98949 252 Pfam PF01925 Sulfite exporter TauE/SafE 12 245 1.3E-35 T 26-04-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 A4V04_RS00125 fdbfef9c86ccac916c6074a69abbee18 179 ProSitePatterns PS00201 Flavodoxin signature. 32 48 - T 26-04-2017 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 A4V04_RS00125 fdbfef9c86ccac916c6074a69abbee18 179 Pfam PF12682 Flavodoxin 29 160 7.2E-15 T 26-04-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A4V04_RS00125 fdbfef9c86ccac916c6074a69abbee18 179 SUPERFAMILY SSF52218 29 160 2.1E-24 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS00125 fdbfef9c86ccac916c6074a69abbee18 179 Gene3D G3DSA:3.40.50.360 29 152 1.8E-18 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS00265 7a94d7c70a20309295e27a5dac8c444b 401 PIRSF PIRSF004640 2 399 1.4E-120 T 26-04-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4V04_RS00265 7a94d7c70a20309295e27a5dac8c444b 401 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 10 389 2.5E-105 T 26-04-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4V04_RS00265 7a94d7c70a20309295e27a5dac8c444b 401 Pfam PF04551 GcpE protein 9 389 3.0E-108 T 26-04-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4V04_RS00265 7a94d7c70a20309295e27a5dac8c444b 401 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 1 391 26.657 T 26-04-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4V04_RS00775 8a393d824683d16ddffdd783b0c1ebe2 343 Gene3D G3DSA:3.40.50.300 47 146 1.4E-6 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00775 8a393d824683d16ddffdd783b0c1ebe2 343 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 4 338 36.086 T 26-04-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 A4V04_RS00775 8a393d824683d16ddffdd783b0c1ebe2 343 SUPERFAMILY SSF52540 48 198 2.8E-10 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS00775 8a393d824683d16ddffdd783b0c1ebe2 343 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 20 334 8.5E-95 T 26-04-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 A4V04_RS00775 8a393d824683d16ddffdd783b0c1ebe2 343 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 19 306 1.2E-70 T 26-04-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 A4V04_RS02165 a634ec27d82dd1ecb1d5b37dcc4e1aae 326 Pfam PF01443 Viral (Superfamily 1) RNA helicase 91 291 1.9E-5 T 26-04-2017 IPR027351 (+) RNA virus helicase core domain GO:0005524 A4V04_RS02165 a634ec27d82dd1ecb1d5b37dcc4e1aae 326 SUPERFAMILY SSF52540 68 296 7.35E-13 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02165 a634ec27d82dd1ecb1d5b37dcc4e1aae 326 Gene3D G3DSA:3.40.50.300 79 177 4.9E-8 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02840 bd250ea7713e5f811709716bd8728f47 1133 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 818 1133 5.7E-56 T 26-04-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 A4V04_RS02840 bd250ea7713e5f811709716bd8728f47 1133 PRINTS PR01484 Pertactin virulence factor family signature 910 934 1.9E-12 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02840 bd250ea7713e5f811709716bd8728f47 1133 PRINTS PR01484 Pertactin virulence factor family signature 1113 1133 1.9E-12 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02840 bd250ea7713e5f811709716bd8728f47 1133 PRINTS PR01484 Pertactin virulence factor family signature 1003 1020 1.9E-12 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02840 bd250ea7713e5f811709716bd8728f47 1133 PRINTS PR01484 Pertactin virulence factor family signature 853 871 1.9E-12 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02840 bd250ea7713e5f811709716bd8728f47 1133 PRINTS PR01484 Pertactin virulence factor family signature 1022 1045 1.9E-12 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02840 bd250ea7713e5f811709716bd8728f47 1133 Pfam PF03797 Autotransporter beta-domain 872 1114 1.7E-36 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02840 bd250ea7713e5f811709716bd8728f47 1133 Gene3D G3DSA:2.40.128.130 836 1133 4.0E-71 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02840 bd250ea7713e5f811709716bd8728f47 1133 SUPERFAMILY SSF103515 847 1133 2.75E-37 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02840 bd250ea7713e5f811709716bd8728f47 1133 SMART SM00869 873 1122 8.1E-32 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02010 a53f845437d5fb210114eac5e351fb9f 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 72 3.1E-9 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS02010 a53f845437d5fb210114eac5e351fb9f 318 SUPERFAMILY SSF46785 12 93 8.16E-12 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02010 a53f845437d5fb210114eac5e351fb9f 318 SUPERFAMILY SSF53850 100 288 1.99E-19 T 26-04-2017 A4V04_RS02010 a53f845437d5fb210114eac5e351fb9f 318 Pfam PF03466 LysR substrate binding domain 99 278 1.3E-14 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS02010 a53f845437d5fb210114eac5e351fb9f 318 Gene3D G3DSA:1.10.10.10 14 93 9.8E-15 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS02010 a53f845437d5fb210114eac5e351fb9f 318 Gene3D G3DSA:3.40.190.10 168 267 2.1E-13 T 26-04-2017 A4V04_RS07625 32c4d7734419ee1d6d59ba36ee8e46d0 237 SUPERFAMILY SSF75217 72 235 2.93E-41 T 26-04-2017 IPR029028 Alpha/beta knot methyltransferases A4V04_RS07625 32c4d7734419ee1d6d59ba36ee8e46d0 237 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 13 232 5.4E-55 T 26-04-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS07625 32c4d7734419ee1d6d59ba36ee8e46d0 237 PIRSF PIRSF015601 1 235 1.1E-52 T 26-04-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS07625 32c4d7734419ee1d6d59ba36ee8e46d0 237 Pfam PF04452 RNA methyltransferase 18 230 1.6E-56 T 26-04-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4V04_RS07625 32c4d7734419ee1d6d59ba36ee8e46d0 237 Gene3D G3DSA:3.40.1280.10 1 236 5.7E-65 T 26-04-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4V04_RS07625 32c4d7734419ee1d6d59ba36ee8e46d0 237 SUPERFAMILY SSF88697 1 66 4.14E-12 T 26-04-2017 IPR015947 PUA-like domain A4V04_RS01540 6288de0f1cb0572ac2a9819004ea729e 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 4.6E-12 T 26-04-2017 A4V04_RS01540 6288de0f1cb0572ac2a9819004ea729e 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 4.6E-12 T 26-04-2017 A4V04_RS01540 6288de0f1cb0572ac2a9819004ea729e 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 4.6E-12 T 26-04-2017 A4V04_RS01540 6288de0f1cb0572ac2a9819004ea729e 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 306 4.6E-12 T 26-04-2017 A4V04_RS01540 6288de0f1cb0572ac2a9819004ea729e 455 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 328 1.3E-43 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS01540 6288de0f1cb0572ac2a9819004ea729e 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 6.8E-10 T 26-04-2017 A4V04_RS01540 6288de0f1cb0572ac2a9819004ea729e 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 188 6.8E-10 T 26-04-2017 A4V04_RS01540 6288de0f1cb0572ac2a9819004ea729e 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 306 6.8E-10 T 26-04-2017 A4V04_RS01540 6288de0f1cb0572ac2a9819004ea729e 455 SUPERFAMILY SSF51905 215 336 1.79E-27 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS01540 6288de0f1cb0572ac2a9819004ea729e 455 SUPERFAMILY SSF51905 11 171 1.79E-27 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS01540 6288de0f1cb0572ac2a9819004ea729e 455 Gene3D G3DSA:3.50.50.60 9 110 2.9E-20 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS01540 6288de0f1cb0572ac2a9819004ea729e 455 Gene3D G3DSA:3.50.50.60 111 335 3.4E-22 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS07910 adc14b72ec2bbf97f7fdd33cdedf0603 312 Gene3D G3DSA:1.20.1630.10 13 310 1.5E-4 T 26-04-2017 A4V04_RS07910 adc14b72ec2bbf97f7fdd33cdedf0603 312 Pfam PF03916 Polysulphide reductase, NrfD 7 309 2.8E-60 T 26-04-2017 IPR005614 NrfD family A4V04_RS10550 e01e905add8fb28bcdda764aa861c09b 218 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 28 214 7.0E-50 T 26-04-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A4V04_RS10550 e01e905add8fb28bcdda764aa861c09b 218 SUPERFAMILY SSF53335 7 214 9.03E-40 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS10550 e01e905add8fb28bcdda764aa861c09b 218 PIRSF PIRSF003078 1 216 6.9E-52 T 26-04-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A4V04_RS10550 e01e905add8fb28bcdda764aa861c09b 218 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 17 211 25.386 T 26-04-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A4V04_RS10550 e01e905add8fb28bcdda764aa861c09b 218 Gene3D G3DSA:3.40.50.150 9 215 6.8E-58 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS10550 e01e905add8fb28bcdda764aa861c09b 218 Pfam PF02527 rRNA small subunit methyltransferase G 24 206 7.7E-50 T 26-04-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A4V04_RS02490 c62317a53c331e0211ee2192238abec1 214 Gene3D G3DSA:3.10.180.10 100 208 2.4E-4 T 26-04-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4V04_RS01350 2c7c119a38690a6c0f0770cb5133c181 192 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 51 85 2.1E-5 T 26-04-2017 IPR001451 Hexapeptide repeat A4V04_RS01350 2c7c119a38690a6c0f0770cb5133c181 192 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 16 49 1.0E-7 T 26-04-2017 IPR001451 Hexapeptide repeat A4V04_RS01350 2c7c119a38690a6c0f0770cb5133c181 192 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 105 137 9.1E-5 T 26-04-2017 IPR001451 Hexapeptide repeat A4V04_RS01350 2c7c119a38690a6c0f0770cb5133c181 192 Gene3D G3DSA:2.160.10.10 4 175 1.4E-42 T 26-04-2017 A4V04_RS01350 2c7c119a38690a6c0f0770cb5133c181 192 SUPERFAMILY SSF51161 3 190 1.18E-45 T 26-04-2017 IPR011004 Trimeric LpxA-like A4V04_RS11830 95884644a07d7161bc1ed0f76caa6dc1 264 PIRSF PIRSF006648 6 261 1.6E-22 T 26-04-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4V04_RS11830 95884644a07d7161bc1ed0f76caa6dc1 264 PRINTS PR00164 ABC-2 type transport system membrane protein signature 66 88 1.6E-10 T 26-04-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4V04_RS11830 95884644a07d7161bc1ed0f76caa6dc1 264 PRINTS PR00164 ABC-2 type transport system membrane protein signature 204 223 1.6E-10 T 26-04-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4V04_RS11830 95884644a07d7161bc1ed0f76caa6dc1 264 PRINTS PR00164 ABC-2 type transport system membrane protein signature 184 203 1.6E-10 T 26-04-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4V04_RS11830 95884644a07d7161bc1ed0f76caa6dc1 264 PRINTS PR00164 ABC-2 type transport system membrane protein signature 147 171 1.6E-10 T 26-04-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4V04_RS11830 95884644a07d7161bc1ed0f76caa6dc1 264 Pfam PF01061 ABC-2 type transporter 17 227 1.5E-31 T 26-04-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4V04_RS13015 5834d03425729dfbbe7b4fc984eae631 310 Gene3D G3DSA:1.10.150.130 12 109 1.1E-20 T 26-04-2017 IPR023109 Integrase/recombinase, N-terminal A4V04_RS13015 5834d03425729dfbbe7b4fc984eae631 310 Gene3D G3DSA:1.10.443.10 114 302 2.0E-37 T 26-04-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS13015 5834d03425729dfbbe7b4fc984eae631 310 SUPERFAMILY SSF56349 12 297 4.04E-54 T 26-04-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4V04_RS13015 5834d03425729dfbbe7b4fc984eae631 310 Pfam PF00589 Phage integrase family 117 291 7.6E-24 T 26-04-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS05130 548e3c6dc822576ffa99a7c4a34398b8 233 Pfam PF03591 AzlC protein 19 152 4.1E-37 T 26-04-2017 IPR011606 Branched-chain amino acid transport, permease A4V04_RS09470 5740d292f122a6e364eb6ce153a61008 184 Gene3D G3DSA:3.40.50.450 2 178 7.1E-57 T 26-04-2017 A4V04_RS09470 5740d292f122a6e364eb6ce153a61008 184 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 3 177 4.6E-45 T 26-04-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG A4V04_RS09470 5740d292f122a6e364eb6ce153a61008 184 Pfam PF03641 Possible lysine decarboxylase 47 176 7.9E-35 T 26-04-2017 IPR031100 LOG family A4V04_RS09470 5740d292f122a6e364eb6ce153a61008 184 SUPERFAMILY SSF102405 2 178 3.36E-53 T 26-04-2017 A4V04_RS08810 0e599c9fdaee97ee223315d5f171755d 323 Gene3D G3DSA:3.40.190.10 169 271 2.2E-13 T 26-04-2017 A4V04_RS08810 0e599c9fdaee97ee223315d5f171755d 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 3.5E-13 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS08810 0e599c9fdaee97ee223315d5f171755d 323 Pfam PF03466 LysR substrate binding domain 93 302 1.3E-18 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS08810 0e599c9fdaee97ee223315d5f171755d 323 Gene3D G3DSA:1.10.10.10 5 87 1.2E-18 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS08810 0e599c9fdaee97ee223315d5f171755d 323 SUPERFAMILY SSF46785 3 113 2.38E-15 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS08810 0e599c9fdaee97ee223315d5f171755d 323 SUPERFAMILY SSF53850 93 302 5.25E-23 T 26-04-2017 A4V04_RS05090 9e55e36a833cebb7b3d6032d68d9feee 185 Gene3D G3DSA:3.40.50.2020 3 166 1.3E-33 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS05090 9e55e36a833cebb7b3d6032d68d9feee 185 Pfam PF00156 Phosphoribosyl transferase domain 48 167 6.1E-16 T 26-04-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4V04_RS05090 9e55e36a833cebb7b3d6032d68d9feee 185 SUPERFAMILY SSF53271 25 163 6.03E-24 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS09830 c6e51cd7dbf6fe25a82b94044cee2ed2 512 Gene3D G3DSA:2.160.20.20 140 216 2.1E-12 T 26-04-2017 IPR012332 P22 tailspike C-terminal domain-like A4V04_RS09830 c6e51cd7dbf6fe25a82b94044cee2ed2 512 Gene3D G3DSA:2.160.20.20 275 512 2.1E-12 T 26-04-2017 IPR012332 P22 tailspike C-terminal domain-like A4V04_RS09830 c6e51cd7dbf6fe25a82b94044cee2ed2 512 SUPERFAMILY SSF51126 303 512 4.39E-7 T 26-04-2017 IPR011050 Pectin lyase fold/virulence factor A4V04_RS06620 4a8261aca36c3d3b76a7f1f71b46186a 256 SUPERFAMILY SSF56784 4 102 2.56E-5 T 26-04-2017 IPR023214 HAD-like domain A4V04_RS01035 ef6fe0df3da14ab8f3ccacbbd654c2ea 300 SUPERFAMILY SSF103481 208 287 3.66E-9 T 26-04-2017 A4V04_RS01035 ef6fe0df3da14ab8f3ccacbbd654c2ea 300 Pfam PF00892 EamA-like transporter family 152 284 1.4E-13 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS01035 ef6fe0df3da14ab8f3ccacbbd654c2ea 300 Pfam PF00892 EamA-like transporter family 16 141 3.3E-12 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS01035 ef6fe0df3da14ab8f3ccacbbd654c2ea 300 SUPERFAMILY SSF103481 46 142 2.48E-10 T 26-04-2017 A4V04_RS07240 81203d7a8739d3f1fbb6f190039a355b 433 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 17 433 7.4E-77 T 26-04-2017 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) A4V04_RS07240 81203d7a8739d3f1fbb6f190039a355b 433 SUPERFAMILY SSF56935 26 433 1.77E-75 T 26-04-2017 A4V04_RS07240 81203d7a8739d3f1fbb6f190039a355b 433 Gene3D G3DSA:2.40.160.60 26 433 1.5E-105 T 26-04-2017 A4V04_RS10955 8777d82de0f3986fb30c3f7c7b570629 383 Gene3D G3DSA:2.40.160.10 22 383 5.1E-48 T 26-04-2017 IPR023614 Porin domain A4V04_RS10955 8777d82de0f3986fb30c3f7c7b570629 383 SUPERFAMILY SSF56935 22 383 1.48E-44 T 26-04-2017 A4V04_RS10955 8777d82de0f3986fb30c3f7c7b570629 383 Pfam PF13609 Gram-negative porin 7 359 3.1E-26 T 26-04-2017 A4V04_RS12000 657b7104c1fe09b8459d425146f77654 266 Pfam PF03799 Cell division protein FtsQ 113 236 1.9E-11 T 26-04-2017 IPR005548 Cell division protein FtsQ/DivIB A4V04_RS12000 657b7104c1fe09b8459d425146f77654 266 Pfam PF08478 POTRA domain, FtsQ-type 45 105 4.7E-15 T 26-04-2017 IPR013685 Polypeptide-transport-associated, FtsQ-type A4V04_RS00325 0e4f3f0dedacfc1a781e91421428a67f 178 Pfam PF00156 Phosphoribosyl transferase domain 7 156 2.6E-26 T 26-04-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4V04_RS00325 0e4f3f0dedacfc1a781e91421428a67f 178 SUPERFAMILY SSF53271 2 169 3.98E-32 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS00325 0e4f3f0dedacfc1a781e91421428a67f 178 Gene3D G3DSA:3.40.50.2020 2 160 7.6E-36 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS10835 3b5454da44455331e79b7af74df1b85c 449 SUPERFAMILY SSF56801 8 430 4.71E-80 T 26-04-2017 A4V04_RS10835 3b5454da44455331e79b7af74df1b85c 449 Gene3D G3DSA:3.40.50.980 107 269 3.8E-26 T 26-04-2017 A4V04_RS10835 3b5454da44455331e79b7af74df1b85c 449 Pfam PF00501 AMP-binding enzyme 88 340 9.4E-42 T 26-04-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4V04_RS10835 3b5454da44455331e79b7af74df1b85c 449 ProSitePatterns PS00455 Putative AMP-binding domain signature. 113 124 - T 26-04-2017 IPR020845 AMP-binding, conserved site A4V04_RS10835 3b5454da44455331e79b7af74df1b85c 449 Gene3D G3DSA:2.30.38.10 278 335 2.4E-11 T 26-04-2017 A4V04_RS10835 3b5454da44455331e79b7af74df1b85c 449 Gene3D G3DSA:3.30.300.30 336 430 1.2E-22 T 26-04-2017 A4V04_RS10835 3b5454da44455331e79b7af74df1b85c 449 Pfam PF13193 AMP-binding enzyme C-terminal domain 350 426 2.2E-13 T 26-04-2017 IPR025110 AMP-binding enzyme C-terminal domain A4V04_RS06150 b1bc2aa4fc4dc278864c196b012503d3 240 Gene3D G3DSA:1.10.3810.10 62 232 1.2E-61 T 26-04-2017 A4V04_RS06150 b1bc2aa4fc4dc278864c196b012503d3 240 SUPERFAMILY SSF53955 61 233 6.75E-59 T 26-04-2017 IPR023346 Lysozyme-like domain A4V04_RS06150 b1bc2aa4fc4dc278864c196b012503d3 240 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 17 236 5.4E-75 T 26-04-2017 IPR011812 Monofunctional biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 A4V04_RS06150 b1bc2aa4fc4dc278864c196b012503d3 240 Pfam PF00912 Transglycosylase 64 231 5.8E-56 T 26-04-2017 IPR001264 Glycosyl transferase, family 51 A4V04_RS02065 cd7c3e16e3cc8c8c3921fb71be2912a0 93 Pfam PF08972 Domain of unknown function (DUF1902) 24 83 3.4E-9 T 26-04-2017 IPR015066 Protein of unknown function DUF1902 A4V04_RS02065 cd7c3e16e3cc8c8c3921fb71be2912a0 93 SUPERFAMILY SSF143100 24 76 1.14E-5 T 26-04-2017 A4V04_RS07670 ed0c2f580c25b4ce839e55d163db8a98 229 Pfam PF00027 Cyclic nucleotide-binding domain 30 114 6.1E-7 T 26-04-2017 IPR000595 Cyclic nucleotide-binding domain A4V04_RS07670 ed0c2f580c25b4ce839e55d163db8a98 229 Gene3D G3DSA:2.60.120.10 5 127 7.5E-10 T 26-04-2017 IPR014710 RmlC-like jelly roll fold A4V04_RS07670 ed0c2f580c25b4ce839e55d163db8a98 229 SUPERFAMILY SSF46785 148 217 6.26E-9 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07670 ed0c2f580c25b4ce839e55d163db8a98 229 SUPERFAMILY SSF51206 16 132 2.36E-10 T 26-04-2017 IPR018490 Cyclic nucleotide-binding-like A4V04_RS07670 ed0c2f580c25b4ce839e55d163db8a98 229 SMART SM00419 170 218 0.0062 T 26-04-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4V04_RS07670 ed0c2f580c25b4ce839e55d163db8a98 229 Gene3D G3DSA:1.10.10.10 153 217 1.9E-10 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07670 ed0c2f580c25b4ce839e55d163db8a98 229 Pfam PF13545 Crp-like helix-turn-helix domain 153 215 1.4E-8 T 26-04-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4V04_RS12690 f3d01f62d62bb6dc27c1f3abbf6ed26a 89 SUPERFAMILY SSF52091 7 82 4.32E-11 T 26-04-2017 IPR002645 STAS domain A4V04_RS12690 f3d01f62d62bb6dc27c1f3abbf6ed26a 89 Gene3D G3DSA:3.30.750.24 8 83 1.1E-10 T 26-04-2017 IPR002645 STAS domain A4V04_RS12690 f3d01f62d62bb6dc27c1f3abbf6ed26a 89 Pfam PF13466 STAS domain 9 79 1.7E-13 T 26-04-2017 IPR002645 STAS domain A4V04_RS00390 49992b1baf2fd913ce93a04fac40eea5 126 Pfam PF04899 MbeD/MobD like 41 88 1.3E-4 T 26-04-2017 IPR006983 MbeD/MobD-like A4V04_RS08440 ba0140a98a8d48e012e120edfd8ebf16 263 Pfam PF10411 Disulfide bond isomerase protein N-terminus 60 101 1.2E-12 T 26-04-2017 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal A4V04_RS08440 ba0140a98a8d48e012e120edfd8ebf16 263 Gene3D G3DSA:3.40.30.10 129 261 2.1E-32 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS08440 ba0140a98a8d48e012e120edfd8ebf16 263 Pfam PF13098 Thioredoxin-like domain 133 256 2.8E-26 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS08440 ba0140a98a8d48e012e120edfd8ebf16 263 SUPERFAMILY SSF52833 103 256 7.77E-27 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS08440 ba0140a98a8d48e012e120edfd8ebf16 263 SUPERFAMILY SSF54423 53 106 1.73E-11 T 26-04-2017 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal A4V04_RS08440 ba0140a98a8d48e012e120edfd8ebf16 263 Gene3D G3DSA:3.10.450.70 53 108 2.7E-15 T 26-04-2017 IPR009094 Disulphide bond isomerase, DsbC, N-terminal A4V04_RS13065 2c599a321d4a9949581f8a2ad74edf56 138 Pfam PF00890 FAD binding domain 10 117 1.1E-14 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS13065 2c599a321d4a9949581f8a2ad74edf56 138 Gene3D G3DSA:3.50.50.60 75 134 3.9E-13 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS13065 2c599a321d4a9949581f8a2ad74edf56 138 Gene3D G3DSA:3.90.700.10 6 70 1.0E-10 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS13065 2c599a321d4a9949581f8a2ad74edf56 138 SUPERFAMILY SSF56425 6 78 1.74E-12 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS08565 51608e375df995ca6c963dbc0c35e51c 361 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 95 338 2.7E-103 T 26-04-2017 IPR019591 Mrp/NBP35 ATP-binding protein A4V04_RS08565 51608e375df995ca6c963dbc0c35e51c 361 Gene3D G3DSA:3.40.50.300 91 338 2.4E-106 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS08565 51608e375df995ca6c963dbc0c35e51c 361 Hamap MF_02040 Iron-sulfur cluster carrier protein. 91 339 36.921 T 26-04-2017 IPR019591 Mrp/NBP35 ATP-binding protein A4V04_RS08565 51608e375df995ca6c963dbc0c35e51c 361 ProSitePatterns PS01215 Mrp family signature. 202 218 - T 26-04-2017 IPR000808 Mrp, conserved site GO:0005524 A4V04_RS08565 51608e375df995ca6c963dbc0c35e51c 361 Pfam PF01883 Domain of unknown function DUF59 6 77 3.1E-13 T 26-04-2017 IPR002744 Domain of unknown function DUF59 A4V04_RS08565 51608e375df995ca6c963dbc0c35e51c 361 SUPERFAMILY SSF117916 2 80 6.54E-10 T 26-04-2017 A4V04_RS08565 51608e375df995ca6c963dbc0c35e51c 361 SUPERFAMILY SSF52540 98 338 1.11E-60 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS03100 9a289e1c3093a639a698981439ab8b9b 271 Gene3D G3DSA:3.40.50.150 9 149 8.3E-23 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS03100 9a289e1c3093a639a698981439ab8b9b 271 Gene3D G3DSA:3.40.50.150 186 214 8.3E-23 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS03100 9a289e1c3093a639a698981439ab8b9b 271 SUPERFAMILY SSF53335 3 204 5.77E-25 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS03100 9a289e1c3093a639a698981439ab8b9b 271 Pfam PF13649 Methyltransferase domain 44 134 1.3E-11 T 26-04-2017 A4V04_RS12630 845b77f104016c366c54745a17fec7be 366 Pfam PF01270 Glycosyl hydrolases family 8 12 336 1.3E-54 T 26-04-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4V04_RS12630 845b77f104016c366c54745a17fec7be 366 PRINTS PR00735 Glycosyl hydrolase family 8 signature 109 127 3.8E-19 T 26-04-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4V04_RS12630 845b77f104016c366c54745a17fec7be 366 PRINTS PR00735 Glycosyl hydrolase family 8 signature 49 62 3.8E-19 T 26-04-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4V04_RS12630 845b77f104016c366c54745a17fec7be 366 PRINTS PR00735 Glycosyl hydrolase family 8 signature 232 241 3.8E-19 T 26-04-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4V04_RS12630 845b77f104016c366c54745a17fec7be 366 PRINTS PR00735 Glycosyl hydrolase family 8 signature 323 337 3.8E-19 T 26-04-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4V04_RS12630 845b77f104016c366c54745a17fec7be 366 PRINTS PR00735 Glycosyl hydrolase family 8 signature 173 190 3.8E-19 T 26-04-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4V04_RS12630 845b77f104016c366c54745a17fec7be 366 PRINTS PR00735 Glycosyl hydrolase family 8 signature 209 220 3.8E-19 T 26-04-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4V04_RS12630 845b77f104016c366c54745a17fec7be 366 Gene3D G3DSA:1.50.10.10 13 345 7.8E-69 T 26-04-2017 IPR012341 Six-hairpin glycosidase GO:0003824 A4V04_RS12630 845b77f104016c366c54745a17fec7be 366 SUPERFAMILY SSF48208 6 343 5.67E-72 T 26-04-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 A4V04_RS10775 c664658e1b75b2f0215029b2c51ad2b7 64 SUPERFAMILY SSF46955 7 54 2.43E-8 T 26-04-2017 IPR009061 Putative DNA-binding domain A4V04_RS10775 c664658e1b75b2f0215029b2c51ad2b7 64 Gene3D G3DSA:1.10.1660.10 9 56 2.5E-8 T 26-04-2017 A4V04_RS10775 c664658e1b75b2f0215029b2c51ad2b7 64 Pfam PF00376 MerR family regulatory protein 9 46 1.2E-9 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS11850 037c4e29fc211af0740f9cdb16283918 193 Pfam PF09605 Hypothetical bacterial integral membrane protein (Trep_Strep) 24 153 9.6E-8 T 26-04-2017 IPR011733 Conserved hypothetical CHP02185, integral membrane A4V04_RS03910 6eef131b4f2a8b4c5d2071a4699ec444 172 Gene3D G3DSA:3.40.630.30 3 139 1.2E-9 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS03910 6eef131b4f2a8b4c5d2071a4699ec444 172 Pfam PF04768 NAT, N-acetyltransferase, of N-acetylglutamate synthase 57 117 4.2E-5 T 26-04-2017 IPR006855 Vertebrate-like NAGS Gcn5-related N-acetyltransferase (GNAT) domain KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154|Reactome: R-HSA-70635 A4V04_RS03910 6eef131b4f2a8b4c5d2071a4699ec444 172 SUPERFAMILY SSF55729 1 130 4.37E-11 T 26-04-2017 IPR016181 Acyl-CoA N-acyltransferase A4V04_RS03750 6b52e8954020d4c1aa508f765846681f 327 Gene3D G3DSA:3.90.1480.10 84 319 7.8E-25 T 26-04-2017 A4V04_RS03750 6b52e8954020d4c1aa508f765846681f 327 ProDom PD024016 LIPOPOLYSACCHARIDE BIOSYNTHESIS CORE RFAZ WAAZ 83 319 4.0E-6 T 26-04-2017 A4V04_RS02755 86c3018d350af97c569a7a9031699f09 401 SUPERFAMILY SSF52540 19 199 3.01E-17 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02755 86c3018d350af97c569a7a9031699f09 401 Pfam PF13173 AAA domain 19 134 5.6E-25 T 26-04-2017 A4V04_RS02755 86c3018d350af97c569a7a9031699f09 401 Pfam PF13635 Domain of unknown function (DUF4143) 196 354 8.1E-26 T 26-04-2017 IPR025420 Domain of unknown function DUF4143 A4V04_RS02755 86c3018d350af97c569a7a9031699f09 401 Gene3D G3DSA:3.40.50.300 5 56 2.2E-4 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10975 e0294af52b176712941101ee6bf028c5 427 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 57 417 8.7E-63 T 26-04-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A4V04_RS10975 e0294af52b176712941101ee6bf028c5 427 Pfam PF03606 C4-dicarboxylate anaerobic carrier 43 425 9.9E-26 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS07470 21db443d55a56754fb1a14527d64cb6c 276 SUPERFAMILY SSF51206 37 150 3.67E-10 T 26-04-2017 IPR018490 Cyclic nucleotide-binding-like A4V04_RS07470 21db443d55a56754fb1a14527d64cb6c 276 Gene3D G3DSA:2.60.120.10 37 157 1.2E-4 T 26-04-2017 IPR014710 RmlC-like jelly roll fold A4V04_RS02780 5f97ff098e482cb25355ae6a57ed8b7a 762 Pfam PF01384 Phosphate transporter family 26 346 1.5E-21 T 26-04-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A4V04_RS12810 fec446d169cf66d44161fabe96bd4746 503 SUPERFAMILY SSF51905 440 500 5.56E-44 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12810 fec446d169cf66d44161fabe96bd4746 503 SUPERFAMILY SSF51905 19 269 5.56E-44 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12810 fec446d169cf66d44161fabe96bd4746 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 28 50 1.4E-7 T 26-04-2017 A4V04_RS12810 fec446d169cf66d44161fabe96bd4746 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 457 472 1.4E-7 T 26-04-2017 A4V04_RS12810 fec446d169cf66d44161fabe96bd4746 503 Gene3D G3DSA:3.50.50.60 437 502 1.6E-67 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12810 fec446d169cf66d44161fabe96bd4746 503 Gene3D G3DSA:3.50.50.60 22 260 1.6E-67 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS12810 fec446d169cf66d44161fabe96bd4746 503 SUPERFAMILY SSF56425 284 441 7.59E-20 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS12810 fec446d169cf66d44161fabe96bd4746 503 Gene3D G3DSA:3.90.700.10 286 430 3.8E-23 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS12810 fec446d169cf66d44161fabe96bd4746 503 Pfam PF00890 FAD binding domain 28 475 1.0E-55 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS02615 ea9fca1af384c09248f410aea4eb2cf2 192 Pfam PF01613 Flavin reductase like domain 23 151 3.9E-8 T 26-04-2017 IPR002563 Flavin reductase like domain GO:0010181 A4V04_RS02615 ea9fca1af384c09248f410aea4eb2cf2 192 Gene3D G3DSA:2.30.110.10 18 164 4.4E-28 T 26-04-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4V04_RS02615 ea9fca1af384c09248f410aea4eb2cf2 192 SUPERFAMILY SSF50475 2 165 1.08E-19 T 26-04-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4V04_RS11985 66965b771613e962a1ed51c46530c85d 470 Pfam PF00939 Sodium:sulfate symporter transmembrane region 7 468 4.7E-123 T 26-04-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A4V04_RS11985 66965b771613e962a1ed51c46530c85d 470 PIRSF PIRSF002457 1 470 2.3E-139 T 26-04-2017 IPR030676 Citrate carrier CitT-related A4V04_RS11985 66965b771613e962a1ed51c46530c85d 470 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 25 464 1.2E-113 T 26-04-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A4V04_RS10240 31b0e250f548105c95d2868cbb8f0dd6 212 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 1 184 29.238 T 26-04-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4V04_RS10240 31b0e250f548105c95d2868cbb8f0dd6 212 Pfam PF01386 Ribosomal L25p family 4 90 3.7E-23 T 26-04-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4V04_RS10240 31b0e250f548105c95d2868cbb8f0dd6 212 Gene3D G3DSA:2.40.240.10 1 93 3.9E-31 T 26-04-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4V04_RS10240 31b0e250f548105c95d2868cbb8f0dd6 212 Gene3D G3DSA:2.170.120.20 96 188 3.0E-25 T 26-04-2017 IPR020057 Ribosomal protein L25, beta domain A4V04_RS10240 31b0e250f548105c95d2868cbb8f0dd6 212 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 1 93 22.356 T 26-04-2017 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4V04_RS10240 31b0e250f548105c95d2868cbb8f0dd6 212 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 183 3.8E-26 T 26-04-2017 IPR020057 Ribosomal protein L25, beta domain A4V04_RS10240 31b0e250f548105c95d2868cbb8f0dd6 212 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 5 175 7.5E-39 T 26-04-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4V04_RS10240 31b0e250f548105c95d2868cbb8f0dd6 212 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 1 93 4.0E-31 T 26-04-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4V04_RS10240 31b0e250f548105c95d2868cbb8f0dd6 212 SUPERFAMILY SSF50715 1 189 2.27E-51 T 26-04-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4V04_RS12625 fdf3b647cf127ff7a8f70efec58bf08e 544 Pfam PF11658 Cellulose biosynthesis protein BcsG 17 539 3.8E-195 T 26-04-2017 IPR017744 Cellulose biosynthesis protein BcsG A4V04_RS12625 fdf3b647cf127ff7a8f70efec58bf08e 544 TIGRFAM TIGR03368 cellulose_yhjU: cellulose synthase operon protein YhjU 15 542 3.7E-164 T 26-04-2017 IPR017744 Cellulose biosynthesis protein BcsG A4V04_RS03670 60652c524d017b54253a65b66b992627 414 Pfam PF01594 Domain of unknown function DUF20 31 358 1.1E-38 T 26-04-2017 IPR002549 Transmembrane protein TqsA-like A4V04_RS02325 5248abbc8d09c1cfd81ffe3bc4ceaa27 525 Gene3D G3DSA:1.10.443.10 185 385 1.8E-9 T 26-04-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS02325 5248abbc8d09c1cfd81ffe3bc4ceaa27 525 SUPERFAMILY SSF56349 69 378 1.0E-11 T 26-04-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4V04_RS02325 5248abbc8d09c1cfd81ffe3bc4ceaa27 525 Pfam PF12835 Integrase 184 333 1.3E-7 T 26-04-2017 IPR024456 Integrase catalytic domain, putative A4V04_RS00655 1066bd523536a211c035b3b09fc807f8 429 Gene3D G3DSA:1.10.443.10 223 406 6.7E-10 T 26-04-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS00655 1066bd523536a211c035b3b09fc807f8 429 Pfam PF00589 Phage integrase family 243 333 2.5E-7 T 26-04-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS00655 1066bd523536a211c035b3b09fc807f8 429 Gene3D G3DSA:1.10.150.130 136 200 5.4E-8 T 26-04-2017 IPR023109 Integrase/recombinase, N-terminal A4V04_RS00655 1066bd523536a211c035b3b09fc807f8 429 Pfam PF13356 Domain of unknown function (DUF4102) 8 73 3.7E-8 T 26-04-2017 IPR025166 Domain of unknown function DUF4102 A4V04_RS00655 1066bd523536a211c035b3b09fc807f8 429 SUPERFAMILY SSF56349 106 416 1.02E-32 T 26-04-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4V04_RS05030 f077c2704f6147d719d0bba1c8843489 596 SUPERFAMILY SSF53098 220 525 7.59E-7 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS05030 f077c2704f6147d719d0bba1c8843489 596 Pfam PF01609 Transposase DDE domain 247 516 4.4E-12 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS07870 feca7e55010bf6ea2872cc9aa7e61b03 276 SUPERFAMILY SSF52402 19 199 5.95E-22 T 26-04-2017 A4V04_RS07870 feca7e55010bf6ea2872cc9aa7e61b03 276 Gene3D G3DSA:3.40.50.620 12 163 8.4E-16 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS09550 446ae181a8c1985cafa0091dc8502e74 218 SMART SM00382 32 218 8.1E-8 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS09550 446ae181a8c1985cafa0091dc8502e74 218 SUPERFAMILY SSF52540 26 200 6.52E-40 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09550 446ae181a8c1985cafa0091dc8502e74 218 Gene3D G3DSA:3.40.50.300 26 199 1.5E-44 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09550 446ae181a8c1985cafa0091dc8502e74 218 Pfam PF00005 ABC transporter 27 170 1.1E-23 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS03250 a3c03f66b49a9fca53e41baa17b4346a 391 Pfam PF06804 NlpB/DapX lipoprotein 35 388 1.1E-39 T 26-04-2017 IPR010653 NlpB/DapX lipoprotein A4V04_RS09885 6b3aabb2ed3cf4d1139f682d079a9aee 463 Pfam PF13520 Amino acid permease 2 431 3.3E-57 T 26-04-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4V04_RS09885 6b3aabb2ed3cf4d1139f682d079a9aee 463 PIRSF PIRSF006060 2 462 1.1E-53 T 26-04-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4V04_RS08090 3182ab8785196ab4d8efb921731284fa 123 Gene3D G3DSA:2.40.50.200 28 122 2.0E-18 T 26-04-2017 IPR005220 Bacterial OB-fold A4V04_RS08090 3182ab8785196ab4d8efb921731284fa 123 SUPERFAMILY SSF101756 48 120 1.96E-16 T 26-04-2017 IPR005220 Bacterial OB-fold A4V04_RS08090 3182ab8785196ab4d8efb921731284fa 123 Pfam PF04076 Bacterial OB fold (BOF) protein 53 120 9.7E-12 T 26-04-2017 IPR005220 Bacterial OB-fold A4V04_RS12320 c8a16b71f413940cf96823c419ba4086 149 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 3 143 4.3E-49 T 26-04-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 A4V04_RS12320 c8a16b71f413940cf96823c419ba4086 149 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 32.138 T 26-04-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 A4V04_RS12320 c8a16b71f413940cf96823c419ba4086 149 Gene3D G3DSA:3.50.80.10 1 144 9.2E-54 T 26-04-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain A4V04_RS12320 c8a16b71f413940cf96823c419ba4086 149 SUPERFAMILY SSF69500 1 144 9.81E-52 T 26-04-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain A4V04_RS12320 c8a16b71f413940cf96823c419ba4086 149 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 144 1.4E-53 T 26-04-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 A4V04_RS03865 e3a7ede831027338b0dd08318f4841ef 158 Pfam PF04993 TfoX N-terminal domain 11 94 1.4E-7 T 26-04-2017 IPR007076 TfoX, N-terminal A4V04_RS03865 e3a7ede831027338b0dd08318f4841ef 158 Gene3D G3DSA:3.30.1460.30 3 95 4.9E-10 T 26-04-2017 IPR007076 TfoX, N-terminal A4V04_RS03865 e3a7ede831027338b0dd08318f4841ef 158 SUPERFAMILY SSF159894 5 97 4.45E-13 T 26-04-2017 A4V04_RS09040 dabea7354ee7260202dcd70c3d27e6cb 287 Gene3D G3DSA:3.40.50.300 1 157 6.2E-11 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09040 dabea7354ee7260202dcd70c3d27e6cb 287 Pfam PF03668 P-loop ATPase protein family 1 283 3.9E-88 T 26-04-2017 IPR005337 RapZ-like family GO:0005524 A4V04_RS09040 dabea7354ee7260202dcd70c3d27e6cb 287 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 284 37.759 T 26-04-2017 IPR005337 RapZ-like family GO:0005524 A4V04_RS09040 dabea7354ee7260202dcd70c3d27e6cb 287 SUPERFAMILY SSF52540 1 155 3.01E-8 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09040 dabea7354ee7260202dcd70c3d27e6cb 287 PIRSF PIRSF005052 1 286 2.6E-102 T 26-04-2017 IPR005337 RapZ-like family GO:0005524 A4V04_RS09145 66b44df4ee8951328c852cec8735b3fc 493 Gene3D G3DSA:3.50.50.60 430 491 8.3E-71 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS09145 66b44df4ee8951328c852cec8735b3fc 493 Gene3D G3DSA:3.50.50.60 24 284 8.3E-71 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS09145 66b44df4ee8951328c852cec8735b3fc 493 SUPERFAMILY SSF51905 14 289 9.12E-44 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS09145 66b44df4ee8951328c852cec8735b3fc 493 SUPERFAMILY SSF51905 433 491 9.12E-44 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS09145 66b44df4ee8951328c852cec8735b3fc 493 SUPERFAMILY SSF56425 313 434 7.85E-25 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS09145 66b44df4ee8951328c852cec8735b3fc 493 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 194 203 9.3E-6 T 26-04-2017 A4V04_RS09145 66b44df4ee8951328c852cec8735b3fc 493 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 32 54 9.3E-6 T 26-04-2017 A4V04_RS09145 66b44df4ee8951328c852cec8735b3fc 493 Pfam PF00890 FAD binding domain 32 462 1.5E-55 T 26-04-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS09145 66b44df4ee8951328c852cec8735b3fc 493 Gene3D G3DSA:3.90.700.10 313 425 3.1E-27 T 26-04-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4V04_RS06400 9fe6b443418f868e1aa4096a76e267b8 88 SUPERFAMILY SSF143011 1 88 1.77E-21 T 26-04-2017 A4V04_RS06400 9fe6b443418f868e1aa4096a76e267b8 88 Pfam PF15738 Bacterial toxin of type II toxin-antitoxin system, YafQ 4 88 1.3E-27 T 26-04-2017 IPR004386 Toxin-antitoxin system, YafQ-like toxin A4V04_RS06400 9fe6b443418f868e1aa4096a76e267b8 88 PIRSF PIRSF006156 1 88 4.5E-22 T 26-04-2017 IPR004386 Toxin-antitoxin system, YafQ-like toxin A4V04_RS06400 9fe6b443418f868e1aa4096a76e267b8 88 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 7 88 5.4E-19 T 26-04-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4V04_RS00310 b3d3b6acd743c1db5a76526c58aaf619 62 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 4 58 4.5E-19 T 26-04-2017 IPR019201 Protein of unknown function DUF2065 A4V04_RS11555 b0320a27a55a6ae080815dc1438bfb12 110 SUPERFAMILY SSF48695 33 104 1.82E-13 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS11555 b0320a27a55a6ae080815dc1438bfb12 110 Gene3D G3DSA:3.90.10.10 8 106 1.1E-11 T 26-04-2017 A4V04_RS11555 b0320a27a55a6ae080815dc1438bfb12 110 Pfam PF14537 Cytochrome c3 29 103 2.4E-18 T 26-04-2017 A4V04_RS13060 b0320a27a55a6ae080815dc1438bfb12 110 SUPERFAMILY SSF48695 33 104 1.82E-13 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS13060 b0320a27a55a6ae080815dc1438bfb12 110 Gene3D G3DSA:3.90.10.10 8 106 1.1E-11 T 26-04-2017 A4V04_RS13060 b0320a27a55a6ae080815dc1438bfb12 110 Pfam PF14537 Cytochrome c3 29 103 2.4E-18 T 26-04-2017 A4V04_RS06545 bbb2147f35fd7e1006ece97e23b45139 94 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 5 84 9.4E-10 T 26-04-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4V04_RS06545 bbb2147f35fd7e1006ece97e23b45139 94 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 83 4.6E-12 T 26-04-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4V04_RS06545 bbb2147f35fd7e1006ece97e23b45139 94 SUPERFAMILY SSF143011 1 82 7.19E-21 T 26-04-2017 A4V04_RS03410 bc62fc767e72f3a1424952676e698172 295 SUPERFAMILY SSF103481 215 291 2.62E-7 T 26-04-2017 A4V04_RS03410 bc62fc767e72f3a1424952676e698172 295 SUPERFAMILY SSF103481 47 143 1.06E-6 T 26-04-2017 A4V04_RS03410 bc62fc767e72f3a1424952676e698172 295 Pfam PF00892 EamA-like transporter family 10 141 5.4E-9 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS03410 bc62fc767e72f3a1424952676e698172 295 Pfam PF00892 EamA-like transporter family 162 289 2.0E-11 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS02120 db0ca71b81bac113b713f160691e803f 311 Pfam PF13391 HNH endonuclease 216 267 2.9E-5 T 26-04-2017 IPR003615 HNH nuclease A4V04_RS04030 59f2135ad0e6cc24efdc31945159e011 175 Pfam PF02834 LigT like Phosphoesterase 19 92 1.2E-8 T 26-04-2017 IPR014051 Phosphoesterase, HXTX A4V04_RS04030 59f2135ad0e6cc24efdc31945159e011 175 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 12 175 16.311 T 26-04-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A4V04_RS04030 59f2135ad0e6cc24efdc31945159e011 175 SUPERFAMILY SSF55144 12 162 7.32E-25 T 26-04-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase A4V04_RS04030 59f2135ad0e6cc24efdc31945159e011 175 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 12 147 1.9E-25 T 26-04-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A4V04_RS04030 59f2135ad0e6cc24efdc31945159e011 175 Gene3D G3DSA:3.90.1140.10 13 163 2.9E-26 T 26-04-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase A4V04_RS00270 0867b7365d27bd9eae84822ca4e31b8f 427 Pfam PF03129 Anticodon binding domain 342 424 2.6E-8 T 26-04-2017 IPR004154 Anticodon-binding A4V04_RS00270 0867b7365d27bd9eae84822ca4e31b8f 427 Pfam PF13393 Histidyl-tRNA synthetase 11 313 1.6E-47 T 26-04-2017 A4V04_RS00270 0867b7365d27bd9eae84822ca4e31b8f 427 Gene3D G3DSA:3.40.50.800 327 423 2.0E-23 T 26-04-2017 IPR004154 Anticodon-binding A4V04_RS00270 0867b7365d27bd9eae84822ca4e31b8f 427 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 4 424 31.505 T 26-04-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A4V04_RS00270 0867b7365d27bd9eae84822ca4e31b8f 427 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 403 6.3E-147 T 26-04-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A4V04_RS00270 0867b7365d27bd9eae84822ca4e31b8f 427 PIRSF PIRSF001549 2 426 8.0E-116 T 26-04-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A4V04_RS00270 0867b7365d27bd9eae84822ca4e31b8f 427 SUPERFAMILY SSF52954 328 424 6.54E-18 T 26-04-2017 IPR004154 Anticodon-binding A4V04_RS00270 0867b7365d27bd9eae84822ca4e31b8f 427 SUPERFAMILY SSF55681 5 319 1.45E-96 T 26-04-2017 A4V04_RS00270 0867b7365d27bd9eae84822ca4e31b8f 427 Gene3D G3DSA:3.30.930.10 5 186 1.3E-88 T 26-04-2017 A4V04_RS00270 0867b7365d27bd9eae84822ca4e31b8f 427 Gene3D G3DSA:3.30.930.10 222 322 1.3E-88 T 26-04-2017 A4V04_RS11740 55ce97eb8c9b8b94092fbf5a01c7a1cd 925 SUPERFAMILY SSF52540 225 417 1.68E-6 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11740 55ce97eb8c9b8b94092fbf5a01c7a1cd 925 Gene3D G3DSA:3.40.50.300 53 169 2.8E-15 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11740 55ce97eb8c9b8b94092fbf5a01c7a1cd 925 Gene3D G3DSA:3.40.50.300 2 17 2.8E-15 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11740 55ce97eb8c9b8b94092fbf5a01c7a1cd 925 Gene3D G3DSA:3.40.50.300 225 263 2.8E-15 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11740 55ce97eb8c9b8b94092fbf5a01c7a1cd 925 Pfam PF04851 Type III restriction enzyme, res subunit 2 259 2.5E-16 T 26-04-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4V04_RS11740 55ce97eb8c9b8b94092fbf5a01c7a1cd 925 SUPERFAMILY SSF52540 2 20 8.54E-13 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11740 55ce97eb8c9b8b94092fbf5a01c7a1cd 925 SUPERFAMILY SSF52540 52 158 8.54E-13 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS11740 55ce97eb8c9b8b94092fbf5a01c7a1cd 925 SUPERFAMILY SSF52540 215 265 8.54E-13 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS10575 c91a5bcbde3dc9036b7062cfd7e467d3 118 Gene3D G3DSA:3.90.10.10 24 112 7.9E-12 T 26-04-2017 A4V04_RS10575 c91a5bcbde3dc9036b7062cfd7e467d3 118 SUPERFAMILY SSF48695 26 114 2.62E-13 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS10575 c91a5bcbde3dc9036b7062cfd7e467d3 118 Pfam PF14537 Cytochrome c3 27 112 2.5E-15 T 26-04-2017 A4V04_RS07395 1f63c12029f60cf6b911de86af18f94d 97 SUPERFAMILY SSF50249 2 92 1.26E-11 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS07395 1f63c12029f60cf6b911de86af18f94d 97 PIRSF PIRSF003135 1 95 2.0E-10 T 26-04-2017 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 A4V04_RS07395 1f63c12029f60cf6b911de86af18f94d 97 Gene3D G3DSA:2.40.50.140 2 92 5.9E-19 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS07275 260790399e4a56e7228d72b24c801f05 376 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 246 318 7.1E-9 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS07275 260790399e4a56e7228d72b24c801f05 376 Pfam PF07282 Putative transposase DNA-binding domain 291 360 1.9E-17 T 26-04-2017 IPR010095 Transposase IS605, OrfB, C-terminal A4V04_RS07275 260790399e4a56e7228d72b24c801f05 376 Pfam PF12323 Helix-turn-helix domain 1 45 9.6E-14 T 26-04-2017 IPR021027 Transposase, putative, helix-turn-helix domain A4V04_RS07275 260790399e4a56e7228d72b24c801f05 376 Pfam PF01385 Probable transposase 174 277 1.3E-19 T 26-04-2017 IPR001959 Probable transposase, IS891/IS1136/IS1341 A4V04_RS05235 aaa1097e611f73a591da785b7cb37b4b 206 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 199 18.06 T 26-04-2017 IPR006008 Intracellular septation protein A GO:0016021 A4V04_RS05235 aaa1097e611f73a591da785b7cb37b4b 206 Pfam PF04279 Intracellular septation protein A 1 198 1.2E-60 T 26-04-2017 IPR006008 Intracellular septation protein A GO:0016021 A4V04_RS07150 5599d20f57512195649ec2a55511b189 388 Gene3D G3DSA:2.40.160.10 256 388 1.7E-66 T 26-04-2017 IPR023614 Porin domain A4V04_RS07150 5599d20f57512195649ec2a55511b189 388 Gene3D G3DSA:2.40.160.10 20 218 1.7E-66 T 26-04-2017 IPR023614 Porin domain A4V04_RS07150 5599d20f57512195649ec2a55511b189 388 SUPERFAMILY SSF56935 21 218 2.01E-51 T 26-04-2017 A4V04_RS07150 5599d20f57512195649ec2a55511b189 388 SUPERFAMILY SSF56935 256 388 2.01E-51 T 26-04-2017 A4V04_RS07150 5599d20f57512195649ec2a55511b189 388 Pfam PF13609 Gram-negative porin 7 364 2.7E-37 T 26-04-2017 A4V04_RS07150 5599d20f57512195649ec2a55511b189 388 PRINTS PR00184 Neisseria sp. porin signature 52 77 3.9E-5 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS07150 5599d20f57512195649ec2a55511b189 388 PRINTS PR00184 Neisseria sp. porin signature 258 284 3.9E-5 T 26-04-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 A4V04_RS00065 4a3194d6f28a007e16129b5fcd26f9ee 424 Pfam PF12704 MacB-like periplasmic core domain 36 218 3.7E-17 T 26-04-2017 IPR025857 MacB-like periplasmic core domain A4V04_RS00065 4a3194d6f28a007e16129b5fcd26f9ee 424 Pfam PF02687 FtsX-like permease family 284 417 9.6E-19 T 26-04-2017 IPR003838 ABC transporter permease protein domain GO:0016020 A4V04_RS00065 4a3194d6f28a007e16129b5fcd26f9ee 424 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 10 424 1.7E-142 T 26-04-2017 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 A4V04_RS08425 b61417ddd97f29a1c1fc93745673515f 230 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 137 159 - T 26-04-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4V04_RS08425 b61417ddd97f29a1c1fc93745673515f 230 Pfam PF00834 Ribulose-phosphate 3 epimerase family 7 208 3.7E-87 T 26-04-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4V04_RS08425 b61417ddd97f29a1c1fc93745673515f 230 Gene3D G3DSA:3.20.20.70 4 222 6.8E-91 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS08425 b61417ddd97f29a1c1fc93745673515f 230 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 35 49 - T 26-04-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4V04_RS08425 b61417ddd97f29a1c1fc93745673515f 230 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 7 214 8.0E-93 T 26-04-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4V04_RS08425 b61417ddd97f29a1c1fc93745673515f 230 SUPERFAMILY SSF51366 4 220 3.83E-73 T 26-04-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A4V04_RS08425 b61417ddd97f29a1c1fc93745673515f 230 PIRSF PIRSF001461 2 230 8.1E-100 T 26-04-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4V04_RS10645 f8f2e9c4b19e99069ffb92b5c189b4fe 114 Pfam PF03899 ATP synthase I chain 6 97 5.9E-12 T 26-04-2017 IPR005598 ATP synthase protein I A4V04_RS01610 93cdb54356fb74a63e4cf22c7281983b 286 SUPERFAMILY SSF103481 39 141 1.15E-10 T 26-04-2017 A4V04_RS01610 93cdb54356fb74a63e4cf22c7281983b 286 SUPERFAMILY SSF103481 194 285 1.83E-12 T 26-04-2017 A4V04_RS01610 93cdb54356fb74a63e4cf22c7281983b 286 Pfam PF00892 EamA-like transporter family 4 138 1.1E-14 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS01610 93cdb54356fb74a63e4cf22c7281983b 286 Pfam PF00892 EamA-like transporter family 150 282 1.2E-14 T 26-04-2017 IPR000620 EamA domain GO:0016020|GO:0016021 A4V04_RS04480 ff73981e62c564957a4e9446d3c40992 484 Pfam PF01926 50S ribosome-binding GTPase 12 153 1.3E-12 T 26-04-2017 IPR006073 GTP binding domain GO:0005525 A4V04_RS04480 ff73981e62c564957a4e9446d3c40992 484 Pfam PF11981 Domain of unknown function (DUF3482) 182 452 5.5E-16 T 26-04-2017 IPR021871 Protein of unknown function DUF3482 A4V04_RS04480 ff73981e62c564957a4e9446d3c40992 484 Gene3D G3DSA:3.40.50.300 8 181 1.5E-21 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04480 ff73981e62c564957a4e9446d3c40992 484 SUPERFAMILY SSF52540 4 173 4.67E-19 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07095 936eccd7ccfbeee8820106cbc36f0202 297 Pfam PF01435 Peptidase family M48 86 293 2.7E-35 T 26-04-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4V04_RS07095 936eccd7ccfbeee8820106cbc36f0202 297 Hamap MF_00188 Protease HtpX [htpX]. 2 293 24.452 T 26-04-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 A4V04_RS07095 936eccd7ccfbeee8820106cbc36f0202 297 Gene3D G3DSA:3.30.2010.10 80 167 1.1E-28 T 26-04-2017 A4V04_RS07095 936eccd7ccfbeee8820106cbc36f0202 297 Gene3D G3DSA:1.20.58.340 11 67 1.7E-4 T 26-04-2017 A4V04_RS07635 b920dd1a4eb7886c1fc2a3f99466438c 399 SUPERFAMILY SSF103473 7 382 2.75E-35 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS07635 b920dd1a4eb7886c1fc2a3f99466438c 399 Gene3D G3DSA:1.20.1250.20 251 384 2.3E-4 T 26-04-2017 A4V04_RS07635 b920dd1a4eb7886c1fc2a3f99466438c 399 Gene3D G3DSA:1.20.1250.20 9 190 1.0E-14 T 26-04-2017 A4V04_RS07635 b920dd1a4eb7886c1fc2a3f99466438c 399 Pfam PF05977 Transmembrane secretion effector 7 379 7.2E-44 T 26-04-2017 IPR010290 Transmembrane secretion effector A4V04_RS09350 f724a3213ce6d6b0c152f1e4f7e721bc 426 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 9 404 9.6E-85 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS09350 f724a3213ce6d6b0c152f1e4f7e721bc 426 Pfam PF07687 Peptidase dimerisation domain 222 305 1.7E-10 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS09350 f724a3213ce6d6b0c152f1e4f7e721bc 426 SUPERFAMILY SSF55031 219 326 5.5E-23 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS09350 f724a3213ce6d6b0c152f1e4f7e721bc 426 SUPERFAMILY SSF53187 333 418 1.85E-57 T 26-04-2017 A4V04_RS09350 f724a3213ce6d6b0c152f1e4f7e721bc 426 SUPERFAMILY SSF53187 5 48 1.85E-57 T 26-04-2017 A4V04_RS09350 f724a3213ce6d6b0c152f1e4f7e721bc 426 SUPERFAMILY SSF53187 86 234 1.85E-57 T 26-04-2017 A4V04_RS09350 f724a3213ce6d6b0c152f1e4f7e721bc 426 Gene3D G3DSA:3.30.70.360 221 325 1.6E-25 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS09350 f724a3213ce6d6b0c152f1e4f7e721bc 426 Gene3D G3DSA:3.40.630.10 7 48 1.3E-66 T 26-04-2017 A4V04_RS09350 f724a3213ce6d6b0c152f1e4f7e721bc 426 Gene3D G3DSA:3.40.630.10 86 216 1.3E-66 T 26-04-2017 A4V04_RS09350 f724a3213ce6d6b0c152f1e4f7e721bc 426 Gene3D G3DSA:3.40.630.10 330 419 1.3E-66 T 26-04-2017 A4V04_RS09350 f724a3213ce6d6b0c152f1e4f7e721bc 426 Pfam PF01546 Peptidase family M20/M25/M40 104 418 1.8E-21 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS09350 f724a3213ce6d6b0c152f1e4f7e721bc 426 PIRSF PIRSF005962 2 425 3.4E-97 T 26-04-2017 IPR017439 Amidohydrolase GO:0016787 A4V04_RS09435 6508cca79e976da11d31f7f3caa5468b 256 SUPERFAMILY SSF69118 28 255 1.88E-38 T 26-04-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4V04_RS09435 6508cca79e976da11d31f7f3caa5468b 256 Gene3D G3DSA:1.20.1290.10 35 133 3.5E-4 T 26-04-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4V04_RS09435 6508cca79e976da11d31f7f3caa5468b 256 Gene3D G3DSA:1.20.1290.10 167 255 6.8E-17 T 26-04-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4V04_RS09435 6508cca79e976da11d31f7f3caa5468b 256 Pfam PF02627 Carboxymuconolactone decarboxylase family 176 254 8.7E-13 T 26-04-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4V04_RS08065 270b1f12d46aefa9b392c026c331de93 608 Pfam PF16188 C-terminal region of peptidase_M24 546 606 7.6E-20 T 26-04-2017 IPR032416 Peptidase M24, C-terminal domain A4V04_RS08065 270b1f12d46aefa9b392c026c331de93 608 SUPERFAMILY SSF53092 7 132 2.62E-12 T 26-04-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal A4V04_RS08065 270b1f12d46aefa9b392c026c331de93 608 Pfam PF00557 Metallopeptidase family M24 314 533 3.4E-42 T 26-04-2017 IPR000994 Peptidase M24, structural domain A4V04_RS08065 270b1f12d46aefa9b392c026c331de93 608 Pfam PF16189 Creatinase/Prolidase N-terminal domain 153 310 3.0E-28 T 26-04-2017 A4V04_RS08065 270b1f12d46aefa9b392c026c331de93 608 SUPERFAMILY SSF55920 307 571 5.1E-50 T 26-04-2017 IPR000994 Peptidase M24, structural domain A4V04_RS08065 270b1f12d46aefa9b392c026c331de93 608 Gene3D G3DSA:3.40.350.10 6 136 1.2E-18 T 26-04-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A4V04_RS08065 270b1f12d46aefa9b392c026c331de93 608 Gene3D G3DSA:3.90.230.10 305 572 1.0E-55 T 26-04-2017 IPR000994 Peptidase M24, structural domain A4V04_RS08065 270b1f12d46aefa9b392c026c331de93 608 Pfam PF01321 Creatinase/Prolidase N-terminal domain 11 143 2.0E-14 T 26-04-2017 IPR000587 Creatinase, N-terminal GO:0016787 A4V04_RS00965 286908cdbcfcf871bbb29ba260308f7b 580 SUPERFAMILY SSF53098 131 340 6.3E-6 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS00965 286908cdbcfcf871bbb29ba260308f7b 580 SUPERFAMILY SSF53098 384 506 6.3E-6 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS00965 286908cdbcfcf871bbb29ba260308f7b 580 Pfam PF01609 Transposase DDE domain 233 486 5.0E-7 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS07230 b68aff7af488e9521f3e95ec60cb22e6 126 SUPERFAMILY SSF46785 57 119 2.15E-6 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS07230 b68aff7af488e9521f3e95ec60cb22e6 126 Gene3D G3DSA:1.10.10.10 60 97 3.6E-6 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01600 9e944414ba79f37409d3a1ba66c219bf 438 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 5 369 4.0E-125 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS01600 9e944414ba79f37409d3a1ba66c219bf 438 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 6 437 7.1E-129 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS01600 9e944414ba79f37409d3a1ba66c219bf 438 PIRSF PIRSF004539 1 438 1.8E-144 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS01520 2bab7ff9fdcaa482053e8a8371ba569d 596 Pfam PF01609 Transposase DDE domain 247 516 4.5E-12 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS01520 2bab7ff9fdcaa482053e8a8371ba569d 596 SUPERFAMILY SSF53098 220 525 9.86E-7 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS01920 2bab7ff9fdcaa482053e8a8371ba569d 596 Pfam PF01609 Transposase DDE domain 247 516 4.5E-12 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS01920 2bab7ff9fdcaa482053e8a8371ba569d 596 SUPERFAMILY SSF53098 220 525 9.86E-7 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS04720 6375160075deb8e9efcdb59fed7aa7c8 298 Pfam PF03466 LysR substrate binding domain 94 278 7.1E-16 T 26-04-2017 IPR005119 LysR, substrate-binding A4V04_RS04720 6375160075deb8e9efcdb59fed7aa7c8 298 Gene3D G3DSA:3.40.190.10 86 185 1.5E-10 T 26-04-2017 A4V04_RS04720 6375160075deb8e9efcdb59fed7aa7c8 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 65 4.4E-17 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS04720 6375160075deb8e9efcdb59fed7aa7c8 298 Gene3D G3DSA:1.10.10.10 7 85 2.0E-20 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04720 6375160075deb8e9efcdb59fed7aa7c8 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.1E-7 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS04720 6375160075deb8e9efcdb59fed7aa7c8 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.1E-7 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS04720 6375160075deb8e9efcdb59fed7aa7c8 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.1E-7 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS04720 6375160075deb8e9efcdb59fed7aa7c8 298 SUPERFAMILY SSF46785 8 86 2.0E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS04720 6375160075deb8e9efcdb59fed7aa7c8 298 SUPERFAMILY SSF53850 91 289 2.35E-18 T 26-04-2017 A4V04_RS04720 6375160075deb8e9efcdb59fed7aa7c8 298 Gene3D G3DSA:3.40.190.10 186 266 9.6E-8 T 26-04-2017 A4V04_RS03255 53495734b0bf46a4924454c154ae7575 180 Gene3D G3DSA:3.10.50.40 6 76 8.2E-15 T 26-04-2017 A4V04_RS03255 53495734b0bf46a4924454c154ae7575 180 Gene3D G3DSA:3.10.50.40 130 149 8.2E-15 T 26-04-2017 A4V04_RS03255 53495734b0bf46a4924454c154ae7575 180 SUPERFAMILY SSF54534 11 147 4.26E-22 T 26-04-2017 A4V04_RS03255 53495734b0bf46a4924454c154ae7575 180 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 10 81 1.1E-6 T 26-04-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 A4V04_RS05600 e63c16ad88f07bc3322cda0814283dd1 357 SMART SM01126 151 307 1.2E-16 T 26-04-2017 IPR024445 ISXO2-like transposase domain A4V04_RS05600 e63c16ad88f07bc3322cda0814283dd1 357 Pfam PF12762 ISXO2-like transposase domain 151 304 3.1E-11 T 26-04-2017 IPR024445 ISXO2-like transposase domain A4V04_RS02225 e63c16ad88f07bc3322cda0814283dd1 357 SMART SM01126 151 307 1.2E-16 T 26-04-2017 IPR024445 ISXO2-like transposase domain A4V04_RS02225 e63c16ad88f07bc3322cda0814283dd1 357 Pfam PF12762 ISXO2-like transposase domain 151 304 3.1E-11 T 26-04-2017 IPR024445 ISXO2-like transposase domain A4V04_RS05880 064adcd3430bd9304b2187769eba73ea 284 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 239 265 - T 26-04-2017 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 A4V04_RS05880 064adcd3430bd9304b2187769eba73ea 284 Pfam PF01148 Cytidylyltransferase family 4 278 3.0E-52 T 26-04-2017 A4V04_RS03170 032453bd2cf87041a16a33acd70387ac 472 Pfam PF16980 Putative citrate transport 29 471 1.1E-190 T 26-04-2017 IPR031566 Putative citrate transporter A4V04_RS00455 c2cf2fc513695a634d936cf9be3ad61e 402 Pfam PF04865 Baseplate J-like protein 80 234 4.1E-17 T 26-04-2017 IPR006949 Baseplate protein J-like A4V04_RS04705 1975fab4c2b9bc3d73f5432538ad88f7 124 Pfam PF03788 LrgA family 12 104 4.3E-23 T 26-04-2017 IPR005538 LrgA/CidA family GO:0016021 A4V04_RS10045 c196b446116472f5bee42f92ac009472 166 SUPERFAMILY SSF55961 6 148 4.34E-21 T 26-04-2017 A4V04_RS10045 c196b446116472f5bee42f92ac009472 166 Gene3D G3DSA:3.30.530.20 5 161 2.5E-31 T 26-04-2017 IPR023393 START-like domain A4V04_RS10045 c196b446116472f5bee42f92ac009472 166 Pfam PF08982 Domain of unknown function (DUF1857) 17 158 2.4E-17 T 26-04-2017 IPR015075 Protein of unknown function DUF1857 A4V04_RS12700 54362127a471670cf0a72a171c87731a 262 Pfam PF04333 MlaA lipoprotein 33 224 9.9E-71 T 26-04-2017 IPR007428 MlaA lipoprotein GO:0016020 A4V04_RS12700 54362127a471670cf0a72a171c87731a 262 PRINTS PR01805 VacJ lipoprotein signature 102 119 3.9E-22 T 26-04-2017 IPR007428 MlaA lipoprotein GO:0016020 A4V04_RS12700 54362127a471670cf0a72a171c87731a 262 PRINTS PR01805 VacJ lipoprotein signature 51 67 3.9E-22 T 26-04-2017 IPR007428 MlaA lipoprotein GO:0016020 A4V04_RS12700 54362127a471670cf0a72a171c87731a 262 PRINTS PR01805 VacJ lipoprotein signature 138 155 3.9E-22 T 26-04-2017 IPR007428 MlaA lipoprotein GO:0016020 A4V04_RS12700 54362127a471670cf0a72a171c87731a 262 PRINTS PR01805 VacJ lipoprotein signature 34 47 3.9E-22 T 26-04-2017 IPR007428 MlaA lipoprotein GO:0016020 A4V04_RS02955 d41733e9064fcb86edd2bfef1bc366d3 91 PIRSF PIRSF003108 1 86 2.1E-22 T 26-04-2017 IPR026262 Antitoxin DinJ GO:0000986|GO:0015643|GO:0044010 A4V04_RS02955 d41733e9064fcb86edd2bfef1bc366d3 91 Pfam PF04221 RelB antitoxin 5 74 1.9E-19 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS02955 d41733e9064fcb86edd2bfef1bc366d3 91 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 1 81 2.5E-21 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS11245 2c9c63500158e7b6f8ddc38422505f93 94 PIRSF PIRSF002144 1 94 1.0E-32 T 26-04-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11245 2c9c63500158e7b6f8ddc38422505f93 94 SUPERFAMILY SSF54570 2 84 7.98E-35 T 26-04-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11245 2c9c63500158e7b6f8ddc38422505f93 94 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 88 9.4E-45 T 26-04-2017 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4V04_RS11245 2c9c63500158e7b6f8ddc38422505f93 94 Pfam PF00203 Ribosomal protein S19 3 83 5.1E-37 T 26-04-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11245 2c9c63500158e7b6f8ddc38422505f93 94 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 26-04-2017 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11245 2c9c63500158e7b6f8ddc38422505f93 94 Gene3D G3DSA:3.30.860.10 1 89 1.9E-40 T 26-04-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11245 2c9c63500158e7b6f8ddc38422505f93 94 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 1.4E-23 T 26-04-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11245 2c9c63500158e7b6f8ddc38422505f93 94 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 1.4E-23 T 26-04-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11245 2c9c63500158e7b6f8ddc38422505f93 94 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 1.4E-23 T 26-04-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS11245 2c9c63500158e7b6f8ddc38422505f93 94 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.932 T 26-04-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4V04_RS09645 9142671ecef19b85b2664c7494d1d59b 227 SUPERFAMILY SSF48452 89 192 1.66E-12 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS09645 9142671ecef19b85b2664c7494d1d59b 227 Gene3D G3DSA:1.25.40.10 131 213 1.0E-22 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS09645 9142671ecef19b85b2664c7494d1d59b 227 Gene3D G3DSA:1.25.40.10 78 130 1.5E-4 T 26-04-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4V04_RS04475 ada5226492df963ffdc5f9efaca3da4e 502 Pfam PF11067 Protein of unknown function (DUF2868) 202 354 3.3E-10 T 26-04-2017 IPR021296 Protein of unknown function DUF2868 A4V04_RS05710 d4b8352c003946eb63efdf386f55e9c8 673 Pfam PF03050 Transposase IS66 family 258 585 2.4E-29 T 26-04-2017 IPR004291 Transposase, IS66 A4V04_RS04160 3369414bbbb127f68ddf5ba9e28dd86a 221 Pfam PF03006 Haemolysin-III related 19 214 1.1E-34 T 26-04-2017 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 A4V04_RS04160 3369414bbbb127f68ddf5ba9e28dd86a 221 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 21 219 2.7E-59 T 26-04-2017 IPR005744 Hly-III GO:0016021|GO:0019835 A4V04_RS12915 d22a7f14f72a471e0b97acf8eb547bc5 347 Pfam PF01032 FecCD transport family 30 344 3.0E-84 T 26-04-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A4V04_RS12915 d22a7f14f72a471e0b97acf8eb547bc5 347 Gene3D G3DSA:1.10.3470.10 13 346 2.9E-92 T 26-04-2017 IPR029022 ABC transporter, BtuC-like A4V04_RS12915 d22a7f14f72a471e0b97acf8eb547bc5 347 SUPERFAMILY SSF81345 14 344 3.4E-74 T 26-04-2017 IPR029022 ABC transporter, BtuC-like A4V04_RS07325 304dbc79ce7f8a446e67276bbd625fe9 556 Gene3D G3DSA:3.40.50.300 340 555 3.0E-62 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07325 304dbc79ce7f8a446e67276bbd625fe9 556 SUPERFAMILY SSF88723 197 251 1.5E-11 T 26-04-2017 IPR029060 PIN domain-like A4V04_RS07325 304dbc79ce7f8a446e67276bbd625fe9 556 SUPERFAMILY SSF88723 101 161 1.5E-11 T 26-04-2017 IPR029060 PIN domain-like A4V04_RS07325 304dbc79ce7f8a446e67276bbd625fe9 556 Pfam PF13638 PIN domain 102 246 2.3E-36 T 26-04-2017 IPR002716 PIN domain A4V04_RS07325 304dbc79ce7f8a446e67276bbd625fe9 556 SMART SM00670 100 234 2.2E-11 T 26-04-2017 IPR002716 PIN domain A4V04_RS07325 304dbc79ce7f8a446e67276bbd625fe9 556 Gene3D G3DSA:3.40.50.1010 197 254 6.9E-9 T 26-04-2017 IPR029060 PIN domain-like A4V04_RS07325 304dbc79ce7f8a446e67276bbd625fe9 556 Gene3D G3DSA:3.40.50.1010 101 160 6.9E-9 T 26-04-2017 IPR029060 PIN domain-like A4V04_RS07325 304dbc79ce7f8a446e67276bbd625fe9 556 Pfam PF02562 PhoH-like protein 343 548 4.3E-54 T 26-04-2017 IPR003714 PhoH-like protein GO:0005524 A4V04_RS07325 304dbc79ce7f8a446e67276bbd625fe9 556 SUPERFAMILY SSF52540 461 536 4.68E-30 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07325 304dbc79ce7f8a446e67276bbd625fe9 556 SUPERFAMILY SSF52540 342 428 4.68E-30 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS07325 304dbc79ce7f8a446e67276bbd625fe9 556 SUPERFAMILY SSF52540 228 303 4.68E-30 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS09825 4abc1bd38cf3fadb34eed741b7b5ae9f 383 Gene3D G3DSA:2.40.128.130 88 381 2.7E-55 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS09825 4abc1bd38cf3fadb34eed741b7b5ae9f 383 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 73 380 6.9E-43 T 26-04-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 A4V04_RS09825 4abc1bd38cf3fadb34eed741b7b5ae9f 383 SUPERFAMILY SSF103515 119 383 2.75E-36 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS09825 4abc1bd38cf3fadb34eed741b7b5ae9f 383 SMART SM00869 127 372 3.9E-31 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS09825 4abc1bd38cf3fadb34eed741b7b5ae9f 383 Pfam PF03797 Autotransporter beta-domain 136 367 2.0E-38 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS09825 4abc1bd38cf3fadb34eed741b7b5ae9f 383 PRINTS PR01484 Pertactin virulence factor family signature 300 321 3.0E-11 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS09825 4abc1bd38cf3fadb34eed741b7b5ae9f 383 PRINTS PR01484 Pertactin virulence factor family signature 338 363 3.0E-11 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS09825 4abc1bd38cf3fadb34eed741b7b5ae9f 383 PRINTS PR01484 Pertactin virulence factor family signature 252 269 3.0E-11 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS09825 4abc1bd38cf3fadb34eed741b7b5ae9f 383 PRINTS PR01484 Pertactin virulence factor family signature 93 111 3.0E-11 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS09825 4abc1bd38cf3fadb34eed741b7b5ae9f 383 PRINTS PR01484 Pertactin virulence factor family signature 271 294 3.0E-11 T 26-04-2017 IPR003991 Pertactin virulence factor family GO:0007155 A4V04_RS02925 0310e8c19d19504aecd6d08ca8ef4745 173 Pfam PF05656 Protein of unknown function (DUF805) 35 161 4.1E-18 T 26-04-2017 IPR008523 Protein of unknown function DUF805 GO:0016021 A4V04_RS03475 1b1682674634c220efee74dcb850b0b4 215 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 43.208 T 26-04-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A4V04_RS03475 1b1682674634c220efee74dcb850b0b4 215 Gene3D G3DSA:3.20.19.10 1 204 1.7E-51 T 26-04-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A4V04_RS03475 1b1682674634c220efee74dcb850b0b4 215 SUPERFAMILY SSF52016 1 201 1.0E-61 T 26-04-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A4V04_RS03475 1b1682674634c220efee74dcb850b0b4 215 Pfam PF00694 Aconitase C-terminal domain 1 131 2.7E-39 T 26-04-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 A4V04_RS03475 1b1682674634c220efee74dcb850b0b4 215 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 6.0E-81 T 26-04-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A4V04_RS09500 f4627bd1b49e5cdf255a44f6b368c5a1 379 Gene3D G3DSA:3.40.50.2300 45 185 3.7E-43 T 26-04-2017 A4V04_RS09500 f4627bd1b49e5cdf255a44f6b368c5a1 379 Pfam PF02608 Basic membrane protein 49 334 2.6E-52 T 26-04-2017 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A4V04_RS09500 f4627bd1b49e5cdf255a44f6b368c5a1 379 SUPERFAMILY SSF53822 195 294 6.36E-5 T 26-04-2017 IPR028082 Periplasmic binding protein-like I A4V04_RS00705 6eea25cdb4dbf2aadd26bb0833e81d57 148 Pfam PF12200 Domain of unknown function (DUF3597) 3 143 8.1E-46 T 26-04-2017 IPR022016 Domain of unknown function DUF3597 A4V04_RS00705 6eea25cdb4dbf2aadd26bb0833e81d57 148 SUPERFAMILY SSF158634 1 148 1.22E-38 T 26-04-2017 A4V04_RS02295 9d0a0daf8e3dc6521983e02530ead10b 163 SUPERFAMILY SSF52540 1 119 1.55E-6 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02295 9d0a0daf8e3dc6521983e02530ead10b 163 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 46 142 1.4E-15 T 26-04-2017 IPR003959 ATPase, AAA-type, core GO:0005524 A4V04_RS02295 9d0a0daf8e3dc6521983e02530ead10b 163 Gene3D G3DSA:3.40.50.300 2 121 3.1E-10 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS01585 39c3316d3a5c253c14f2986dd9a44c36 136 SUPERFAMILY SSF55031 20 103 4.45E-8 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS01585 39c3316d3a5c253c14f2986dd9a44c36 136 Gene3D G3DSA:3.30.70.360 17 110 5.0E-7 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS01585 39c3316d3a5c253c14f2986dd9a44c36 136 Pfam PF07687 Peptidase dimerisation domain 17 107 5.6E-8 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS05560 bd5b0069c061fa706529ebd59d9691ed 200 Pfam PF05713 Bacterial mobilisation protein (MobC) 126 167 4.1E-7 T 26-04-2017 IPR008687 Bacterial mobilisation A4V04_RS02480 efb6a8cd8ac3f602fbc278d661acac58 310 Pfam PF03547 Membrane transport protein 164 301 6.4E-8 T 26-04-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A4V04_RS09695 ceb32b1c8f688a670a0e7c75a0c1de79 357 SUPERFAMILY SSF53850 142 327 3.03E-11 T 26-04-2017 A4V04_RS09695 ceb32b1c8f688a670a0e7c75a0c1de79 357 Gene3D G3DSA:3.40.190.10 207 309 4.7E-7 T 26-04-2017 A4V04_RS09695 ceb32b1c8f688a670a0e7c75a0c1de79 357 SUPERFAMILY SSF46785 16 105 1.7E-17 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09695 ceb32b1c8f688a670a0e7c75a0c1de79 357 Gene3D G3DSA:1.10.10.10 7 115 9.7E-23 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS09695 ceb32b1c8f688a670a0e7c75a0c1de79 357 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 28 84 2.7E-12 T 26-04-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4V04_RS09695 ceb32b1c8f688a670a0e7c75a0c1de79 357 Pfam PF12727 PBP superfamily domain 147 328 2.3E-47 T 26-04-2017 IPR024370 PBP domain A4V04_RS12495 edb20ac1b24fab8697678d4852fe141b 112 SUPERFAMILY SSF48695 19 106 5.2E-14 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS12495 edb20ac1b24fab8697678d4852fe141b 112 Pfam PF14537 Cytochrome c3 31 106 6.5E-15 T 26-04-2017 A4V04_RS12495 edb20ac1b24fab8697678d4852fe141b 112 Gene3D G3DSA:3.90.10.10 22 106 1.2E-11 T 26-04-2017 A4V04_RS01755 496cf3ecc5ca8e970b663b0d80491ced 963 Pfam PF07916 TraG-like protein, N-terminal region 5 457 1.9E-83 T 26-04-2017 IPR012931 TraG-like, N-terminal A4V04_RS10690 a59f4883567a7c698717a22c2c3a37f8 122 Pfam PF00582 Universal stress protein family 2 122 5.6E-19 T 26-04-2017 IPR006016 UspA GO:0006950 A4V04_RS10690 a59f4883567a7c698717a22c2c3a37f8 122 Gene3D G3DSA:3.40.50.620 2 122 5.7E-25 T 26-04-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4V04_RS10690 a59f4883567a7c698717a22c2c3a37f8 122 SUPERFAMILY SSF52402 2 122 1.95E-26 T 26-04-2017 A4V04_RS07505 211cee55a72e1768d4e6b605838a1d5b 146 SUPERFAMILY SSF52833 7 141 2.41E-17 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS07505 211cee55a72e1768d4e6b605838a1d5b 146 Gene3D G3DSA:3.40.30.10 15 138 1.2E-18 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS07505 211cee55a72e1768d4e6b605838a1d5b 146 Pfam PF13098 Thioredoxin-like domain 18 128 3.4E-19 T 26-04-2017 IPR012336 Thioredoxin-like fold A4V04_RS08505 cf0b1059ee65d1cf8aa7f06f80918dc5 1152 SUPERFAMILY SSF103515 889 1147 1.96E-8 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS02800 7a5dbbd4c866ffec2c3278304ab796c9 1022 Hamap MF_00970 Ribonuclease E [rne]. 1 977 31.554 T 26-04-2017 IPR028878 Ribonuclease E GO:0006396|GO:0008995 A4V04_RS02800 7a5dbbd4c866ffec2c3278304ab796c9 1022 Pfam PF10150 Ribonuclease E/G family 120 412 6.7E-95 T 26-04-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A4V04_RS02800 7a5dbbd4c866ffec2c3278304ab796c9 1022 Gene3D G3DSA:2.40.50.140 30 124 3.4E-31 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS02800 7a5dbbd4c866ffec2c3278304ab796c9 1022 SMART SM00316 37 118 5.5E-8 T 26-04-2017 IPR022967 RNA-binding domain, S1 A4V04_RS02800 7a5dbbd4c866ffec2c3278304ab796c9 1022 Pfam PF00575 S1 RNA binding domain 36 117 8.9E-10 T 26-04-2017 IPR003029 S1 domain GO:0003676 A4V04_RS02800 7a5dbbd4c866ffec2c3278304ab796c9 1022 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 446 1.7E-152 T 26-04-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 A4V04_RS02800 7a5dbbd4c866ffec2c3278304ab796c9 1022 SUPERFAMILY SSF50249 40 124 1.86E-16 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS02290 09c2a31c94ace8b74c72bd0185bc78e2 156 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 17 98 7.7E-11 T 26-04-2017 IPR003959 ATPase, AAA-type, core GO:0005524 A4V04_RS02290 09c2a31c94ace8b74c72bd0185bc78e2 156 Gene3D G3DSA:3.40.50.300 23 116 6.7E-7 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12300 374f6fca8a7665a7ef9e202ec6e12705 123 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 18 123 7.2E-39 T 26-04-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 A4V04_RS12300 374f6fca8a7665a7ef9e202ec6e12705 123 Gene3D G3DSA:2.60.300.12 16 109 1.4E-32 T 26-04-2017 IPR000361 FeS cluster biogenesis A4V04_RS12300 374f6fca8a7665a7ef9e202ec6e12705 123 SUPERFAMILY SSF89360 16 109 4.9E-32 T 26-04-2017 IPR000361 FeS cluster biogenesis A4V04_RS12300 374f6fca8a7665a7ef9e202ec6e12705 123 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 123 36.865 T 26-04-2017 IPR023063 FeS cluster insertion protein ErpA GO:0016226 A4V04_RS12300 374f6fca8a7665a7ef9e202ec6e12705 123 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 104 121 - T 26-04-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site A4V04_RS12300 374f6fca8a7665a7ef9e202ec6e12705 123 Pfam PF01521 Iron-sulphur cluster biosynthesis 18 118 1.5E-19 T 26-04-2017 IPR000361 FeS cluster biogenesis A4V04_RS07210 9b3112466c9e573d0e652627bdd218ef 383 SUPERFAMILY SSF82861 39 124 1.44E-8 T 26-04-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A4V04_RS07210 9b3112466c9e573d0e652627bdd218ef 383 Gene3D G3DSA:2.30.30.60 143 191 2.5E-10 T 26-04-2017 A4V04_RS07210 9b3112466c9e573d0e652627bdd218ef 383 SUPERFAMILY SSF50182 126 192 9.81E-11 T 26-04-2017 IPR010920 LSM domain A4V04_RS07210 9b3112466c9e573d0e652627bdd218ef 383 Gene3D G3DSA:3.30.70.100 199 286 3.6E-10 T 26-04-2017 A4V04_RS07210 9b3112466c9e573d0e652627bdd218ef 383 SUPERFAMILY SSF82689 198 295 5.36E-13 T 26-04-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A4V04_RS07210 9b3112466c9e573d0e652627bdd218ef 383 Pfam PF00924 Mechanosensitive ion channel 87 287 1.5E-35 T 26-04-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A4V04_RS09795 161b5a6c74af9ac17b62a4e755f54243 176 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 41 168 9.4E-17 T 26-04-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 A4V04_RS09795 161b5a6c74af9ac17b62a4e755f54243 176 Pfam PF04093 rod shape-determining protein MreD 41 169 3.3E-12 T 26-04-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 A4V04_RS02130 aead7b870f9da3856e54cdecf66eefc4 439 PIRSF PIRSF004539 1 439 9.7E-157 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS02130 aead7b870f9da3856e54cdecf66eefc4 439 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 5 438 3.4E-143 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS02130 aead7b870f9da3856e54cdecf66eefc4 439 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 5 371 1.3E-138 T 26-04-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A4V04_RS04710 a5fcdee96afb7ccaf129f1e07926125f 242 Pfam PF04172 LrgB-like family 22 234 1.4E-76 T 26-04-2017 IPR007300 CidB/LrgB family A4V04_RS06855 6b548facb1e8532a700fff353ac9a824 72 Pfam PF01455 HupF/HypC family 1 66 1.1E-25 T 26-04-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A4V04_RS06855 6b548facb1e8532a700fff353ac9a824 72 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 18 34 5.5E-20 T 26-04-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A4V04_RS06855 6b548facb1e8532a700fff353ac9a824 72 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 57 69 5.5E-20 T 26-04-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A4V04_RS06855 6b548facb1e8532a700fff353ac9a824 72 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 5.5E-20 T 26-04-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A4V04_RS06855 6b548facb1e8532a700fff353ac9a824 72 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 39 55 5.5E-20 T 26-04-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A4V04_RS06855 6b548facb1e8532a700fff353ac9a824 72 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 67 9.0E-24 T 26-04-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A4V04_RS06855 6b548facb1e8532a700fff353ac9a824 72 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 26-04-2017 IPR019812 Hydrogenase assembly chaperone, conserved site A4V04_RS06855 6b548facb1e8532a700fff353ac9a824 72 SUPERFAMILY SSF159127 1 68 4.05E-22 T 26-04-2017 A4V04_RS11885 3d6ac94a70bfb95cb5a08fc0b9497285 267 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 188 264 1.6E-9 T 26-04-2017 IPR006260 TonB, C-terminal GO:0006810 A4V04_RS11885 3d6ac94a70bfb95cb5a08fc0b9497285 267 SUPERFAMILY SSF74653 163 264 3.66E-9 T 26-04-2017 A4V04_RS11885 3d6ac94a70bfb95cb5a08fc0b9497285 267 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 187 264 3.1E-10 T 26-04-2017 IPR006260 TonB, C-terminal GO:0006810 A4V04_RS11885 3d6ac94a70bfb95cb5a08fc0b9497285 267 Gene3D G3DSA:3.30.1150.10 155 237 3.4E-8 T 26-04-2017 A4V04_RS02260 99ffc512cb910e34575aaf32a67bb2e3 276 SUPERFAMILY SSF52266 123 232 4.89E-8 T 26-04-2017 IPR013830 SGNH hydrolase-type esterase domain A4V04_RS02260 99ffc512cb910e34575aaf32a67bb2e3 276 Gene3D G3DSA:3.40.50.1110 149 235 2.7E-5 T 26-04-2017 IPR013830 SGNH hydrolase-type esterase domain A4V04_RS10440 eb1b93eea7b823cde084358a056d1827 249 Gene3D G3DSA:1.10.3720.10 52 245 3.0E-20 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS10440 eb1b93eea7b823cde084358a056d1827 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 247 4.1E-27 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS10440 eb1b93eea7b823cde084358a056d1827 249 SUPERFAMILY SSF161098 50 235 2.75E-31 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS01535 aef0780947dc41a10c3c89cd8edd2828 200 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 4 193 1.8E-34 T 26-04-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A4V04_RS01535 aef0780947dc41a10c3c89cd8edd2828 200 Pfam PF01914 MarC family integral membrane protein 5 197 1.8E-39 T 26-04-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A4V04_RS04170 4c6ace57729ee451bbed59844340babd 103 Gene3D G3DSA:1.10.1130.10 34 95 9.7E-8 T 26-04-2017 IPR012286 Tetrahaem cytochrome domain A4V04_RS04170 4c6ace57729ee451bbed59844340babd 103 Pfam PF14537 Cytochrome c3 38 95 1.2E-10 T 26-04-2017 A4V04_RS04170 4c6ace57729ee451bbed59844340babd 103 SUPERFAMILY SSF48695 39 97 7.71E-12 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS00140 e84b882f7a112ea468ec74b50c3ac302 168 Gene3D G3DSA:2.30.110.10 7 153 2.4E-32 T 26-04-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4V04_RS00140 e84b882f7a112ea468ec74b50c3ac302 168 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 15 151 1.1E-20 T 26-04-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related A4V04_RS00140 e84b882f7a112ea468ec74b50c3ac302 168 SUPERFAMILY SSF50475 7 153 1.61E-31 T 26-04-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4V04_RS05545 c89a8742233d3e8d78c1dc4d7c0a4d23 341 Pfam PF01609 Transposase DDE domain 245 323 2.2E-6 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS09240 175de9f538f51d2b10206c099f049bd3 155 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 19 151 3.6E-34 T 26-04-2017 IPR005247 YbhB/YbcL A4V04_RS09240 175de9f538f51d2b10206c099f049bd3 155 SUPERFAMILY SSF49777 1 152 3.66E-42 T 26-04-2017 IPR008914 Phosphatidylethanolamine-binding protein A4V04_RS09240 175de9f538f51d2b10206c099f049bd3 155 Pfam PF01161 Phosphatidylethanolamine-binding protein 14 151 4.7E-32 T 26-04-2017 IPR008914 Phosphatidylethanolamine-binding protein A4V04_RS09240 175de9f538f51d2b10206c099f049bd3 155 Gene3D G3DSA:3.90.280.10 1 152 2.2E-48 T 26-04-2017 IPR008914 Phosphatidylethanolamine-binding protein A4V04_RS06730 2629fb64e7334966da7414616ab4aeb4 410 SUPERFAMILY SSF103473 4 395 3.53E-48 T 26-04-2017 IPR020846 Major facilitator superfamily domain A4V04_RS06730 2629fb64e7334966da7414616ab4aeb4 410 Gene3D G3DSA:1.20.1250.20 216 395 5.2E-10 T 26-04-2017 A4V04_RS06730 2629fb64e7334966da7414616ab4aeb4 410 Pfam PF07690 Major Facilitator Superfamily 29 365 1.2E-28 T 26-04-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4V04_RS06730 2629fb64e7334966da7414616ab4aeb4 410 Gene3D G3DSA:1.20.1250.20 14 182 1.9E-22 T 26-04-2017 A4V04_RS08635 3d21ca3f3d1f41489f9554b835e1ba83 446 SUPERFAMILY SSF54534 299 398 7.85E-28 T 26-04-2017 A4V04_RS08635 3d21ca3f3d1f41489f9554b835e1ba83 446 Gene3D G3DSA:3.10.50.40 294 420 1.1E-33 T 26-04-2017 A4V04_RS08635 3d21ca3f3d1f41489f9554b835e1ba83 446 Gene3D G3DSA:3.10.50.40 184 291 3.5E-26 T 26-04-2017 A4V04_RS08635 3d21ca3f3d1f41489f9554b835e1ba83 446 Hamap MF_01183 Chaperone SurA [surA]. 2 442 29.812 T 26-04-2017 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 A4V04_RS08635 3d21ca3f3d1f41489f9554b835e1ba83 446 SUPERFAMILY SSF109998 39 214 1.96E-40 T 26-04-2017 IPR027304 Trigger factor/SurA domain A4V04_RS08635 3d21ca3f3d1f41489f9554b835e1ba83 446 SUPERFAMILY SSF54534 186 288 2.29E-21 T 26-04-2017 A4V04_RS08635 3d21ca3f3d1f41489f9554b835e1ba83 446 Pfam PF00639 PPIC-type PPIASE domain 318 396 3.1E-21 T 26-04-2017 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 A4V04_RS08635 3d21ca3f3d1f41489f9554b835e1ba83 446 Pfam PF09312 SurA N-terminal domain 39 156 3.1E-38 T 26-04-2017 IPR015391 SurA N-terminal A4V04_RS08635 3d21ca3f3d1f41489f9554b835e1ba83 446 Gene3D G3DSA:1.10.3120.10 51 129 4.1E-4 T 26-04-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A4V04_RS08635 3d21ca3f3d1f41489f9554b835e1ba83 446 Pfam PF13616 PPIC-type PPIASE domain 186 283 4.5E-14 T 26-04-2017 A4V04_RS09445 82da020a3159405375e6bbaf8f994aa6 339 Pfam PF04015 Domain of unknown function (DUF362) 81 292 7.5E-24 T 26-04-2017 IPR007160 Domain of unknown function DUF362 A4V04_RS11910 708d9fffc274a5c67cedb68ba12810cb 447 Pfam PF03606 C4-dicarboxylate anaerobic carrier 61 445 9.3E-23 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS12235 350a2962ae065a8f1d2d717be6591ba0 353 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 119 342 2.7E-14 T 26-04-2017 IPR005079 Peptidase C45 A4V04_RS04605 5bc9d8283978a6455238aa769acd1f30 203 Pfam PF02677 Uncharacterized BCR, COG1636 16 190 2.1E-62 T 26-04-2017 IPR003828 Protein of unknown function DUF208 A4V04_RS00615 74fd450155f9bb3a340c6d9a0844ad97 57 Gene3D G3DSA:3.30.920.30 1 57 1.4E-7 T 26-04-2017 A4V04_RS00615 74fd450155f9bb3a340c6d9a0844ad97 57 SUPERFAMILY SSF54786 1 57 1.26E-8 T 26-04-2017 A4V04_RS03675 cd4b5581a9d7051d0b4f563bbb99e0c2 129 SUPERFAMILY SSF46785 12 111 6.69E-33 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS03675 cd4b5581a9d7051d0b4f563bbb99e0c2 129 Pfam PF01638 HxlR-like helix-turn-helix 23 111 1.2E-30 T 26-04-2017 IPR002577 Helix-turn-helix, HxlR type A4V04_RS03675 cd4b5581a9d7051d0b4f563bbb99e0c2 129 Gene3D G3DSA:1.10.10.10 5 111 3.4E-42 T 26-04-2017 IPR011991 Winged helix-turn-helix DNA-binding domain A4V04_RS01850 a844a83c11b4ca25be65d79ff1a0c37f 199 Pfam PF14348 Domain of unknown function (DUF4400) 71 196 3.0E-13 T 26-04-2017 IPR022266 Integrating conjugative element protein, PFL4697-type A4V04_RS01640 3f027fc924094228ca0e67339bb67821 263 Gene3D G3DSA:3.40.50.1820 53 236 1.1E-5 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS01640 3f027fc924094228ca0e67339bb67821 263 SUPERFAMILY SSF53474 50 215 1.73E-10 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS09920 c050a87c3e90feedbb39ffa206873f91 222 SUPERFAMILY SSF101327 18 188 6.02E-8 T 26-04-2017 IPR011978 Uncharacterised protein family UPF0149 A4V04_RS09920 c050a87c3e90feedbb39ffa206873f91 222 Pfam PF03695 Uncharacterised protein family (UPF0149) 25 188 2.0E-12 T 26-04-2017 IPR011978 Uncharacterised protein family UPF0149 A4V04_RS08980 eb2d608dcad5f9d79ce8b0b9c4a1cc68 250 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 249 6.4E-50 T 26-04-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A4V04_RS08980 eb2d608dcad5f9d79ce8b0b9c4a1cc68 250 SUPERFAMILY SSF52096 3 250 2.25E-61 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS08980 eb2d608dcad5f9d79ce8b0b9c4a1cc68 250 Gene3D G3DSA:3.90.226.10 4 249 2.1E-62 T 26-04-2017 IPR029045 ClpP/crotonase-like domain A4V04_RS08580 5af98447d983274096c04726db2466bb 585 SUPERFAMILY SSF52091 459 558 2.35E-9 T 26-04-2017 IPR002645 STAS domain A4V04_RS08580 5af98447d983274096c04726db2466bb 585 Pfam PF00916 Sulfate permease family 35 399 4.5E-84 T 26-04-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A4V04_RS08580 5af98447d983274096c04726db2466bb 585 Gene3D G3DSA:3.30.750.24 462 558 6.2E-7 T 26-04-2017 IPR002645 STAS domain A4V04_RS06695 1e53ce85df30edc1e36fc9f541974846 186 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 40 55 9.9E-12 T 26-04-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4V04_RS06695 1e53ce85df30edc1e36fc9f541974846 186 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 66 78 9.9E-12 T 26-04-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4V04_RS06695 1e53ce85df30edc1e36fc9f541974846 186 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 140 155 9.9E-12 T 26-04-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4V04_RS06695 1e53ce85df30edc1e36fc9f541974846 186 Gene3D G3DSA:2.40.100.10 25 185 1.7E-58 T 26-04-2017 IPR029000 Cyclophilin-like domain A4V04_RS06695 1e53ce85df30edc1e36fc9f541974846 186 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 27 183 6.7E-52 T 26-04-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4V04_RS06695 1e53ce85df30edc1e36fc9f541974846 186 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 61 78 - T 26-04-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 A4V04_RS06695 1e53ce85df30edc1e36fc9f541974846 186 SUPERFAMILY SSF50891 24 185 3.07E-60 T 26-04-2017 IPR029000 Cyclophilin-like domain A4V04_RS10895 c1de22a99289e1d4653dd5ffbf9db038 379 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 361 7.2E-104 T 26-04-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4V04_RS10895 c1de22a99289e1d4653dd5ffbf9db038 379 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 379 2.1E-153 T 26-04-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4V04_RS10895 c1de22a99289e1d4653dd5ffbf9db038 379 PIRSF PIRSF000267 2 378 3.3E-119 T 26-04-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4V04_RS10530 cd1d2883bc46b1ffbbc3ddd01f14faf6 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 8.1E-8 T 26-04-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4V04_RS10530 cd1d2883bc46b1ffbbc3ddd01f14faf6 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 8.1E-8 T 26-04-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4V04_RS10530 cd1d2883bc46b1ffbbc3ddd01f14faf6 191 Gene3D G3DSA:1.10.357.10 14 189 8.9E-27 T 26-04-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4V04_RS10530 cd1d2883bc46b1ffbbc3ddd01f14faf6 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 1.2E-11 T 26-04-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4V04_RS10530 cd1d2883bc46b1ffbbc3ddd01f14faf6 191 SUPERFAMILY SSF46689 9 83 1.54E-16 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS10445 3eff6e34f4b1808056f880f41c7ea4a9 222 SMART SM00749 53 113 63.0 T 26-04-2017 IPR014004 Transport-associated and nodulation domain, bacteria A4V04_RS10445 3eff6e34f4b1808056f880f41c7ea4a9 222 SMART SM00749 127 190 0.0028 T 26-04-2017 IPR014004 Transport-associated and nodulation domain, bacteria A4V04_RS10445 3eff6e34f4b1808056f880f41c7ea4a9 222 Pfam PF04972 BON domain 46 111 7.3E-16 T 26-04-2017 IPR007055 BON domain A4V04_RS10445 3eff6e34f4b1808056f880f41c7ea4a9 222 Pfam PF04972 BON domain 122 187 8.8E-13 T 26-04-2017 IPR007055 BON domain A4V04_RS12465 3223d41eb5eb714c42abc534c1a18a91 451 Pfam PF14239 RRXRR protein 5 184 2.8E-67 T 26-04-2017 IPR025938 RRXRR domain A4V04_RS12465 3223d41eb5eb714c42abc534c1a18a91 451 Pfam PF14279 HNH endonuclease 203 254 1.2E-14 T 26-04-2017 IPR029471 HNH endonuclease 5 A4V04_RS12465 3223d41eb5eb714c42abc534c1a18a91 451 SMART SM00507 190 241 3.4E-12 T 26-04-2017 IPR003615 HNH nuclease A4V04_RS02600 cc6137ecc10eb0d71586828dfb506220 424 ProSitePatterns PS01007 Transposases, Mutator family, signature. 254 278 - T 26-04-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4V04_RS02600 cc6137ecc10eb0d71586828dfb506220 424 Pfam PF00872 Transposase, Mutator family 36 401 3.8E-109 T 26-04-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4V04_RS07125 9353d97f257a24d9a8b53883905c56f4 477 Pfam PF02743 Cache domain 42 263 5.0E-18 T 26-04-2017 IPR033479 Double Cache domain 1 A4V04_RS07125 9353d97f257a24d9a8b53883905c56f4 477 Gene3D G3DSA:3.30.450.20 77 179 8.0E-9 T 26-04-2017 A4V04_RS07105 039117852ec714e461f6bc0cb1ec2fa7 274 Pfam PF04015 Domain of unknown function (DUF362) 13 227 7.9E-31 T 26-04-2017 IPR007160 Domain of unknown function DUF362 A4V04_RS12500 d92e43a231785137c82c6d540f15b8f4 251 SUPERFAMILY SSF53335 28 161 2.46E-10 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS12500 d92e43a231785137c82c6d540f15b8f4 251 Gene3D G3DSA:3.40.50.150 149 159 2.5E-11 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS12500 d92e43a231785137c82c6d540f15b8f4 251 Gene3D G3DSA:3.40.50.150 33 117 2.5E-11 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS07905 a887bbca099743a2e69934f87858c256 166 Pfam PF05573 NosL 16 159 1.1E-42 T 26-04-2017 IPR008719 Nitrous oxide reductase accessory protein NosL A4V04_RS07905 a887bbca099743a2e69934f87858c256 166 SUPERFAMILY SSF160387 54 164 1.44E-28 T 26-04-2017 A4V04_RS09065 39128b4f76682cd6b37c0d76e9da95ff 335 PIRSF PIRSF002825 13 331 4.1E-63 T 26-04-2017 IPR026045 Ferric binding protein A4V04_RS09065 39128b4f76682cd6b37c0d76e9da95ff 335 Pfam PF13343 Bacterial extracellular solute-binding protein 76 298 1.3E-31 T 26-04-2017 A4V04_RS09065 39128b4f76682cd6b37c0d76e9da95ff 335 SUPERFAMILY SSF53850 27 327 1.51E-69 T 26-04-2017 A4V04_RS09065 39128b4f76682cd6b37c0d76e9da95ff 335 Gene3D G3DSA:3.40.190.10 126 260 1.2E-32 T 26-04-2017 A4V04_RS09065 39128b4f76682cd6b37c0d76e9da95ff 335 Gene3D G3DSA:3.40.190.10 261 294 4.2E-35 T 26-04-2017 A4V04_RS09065 39128b4f76682cd6b37c0d76e9da95ff 335 Gene3D G3DSA:3.40.190.10 26 123 4.2E-35 T 26-04-2017 A4V04_RS09065 39128b4f76682cd6b37c0d76e9da95ff 335 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 145 159 3.7E-5 T 26-04-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A4V04_RS09065 39128b4f76682cd6b37c0d76e9da95ff 335 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 241 260 3.7E-5 T 26-04-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A4V04_RS09065 39128b4f76682cd6b37c0d76e9da95ff 335 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 48 69 3.7E-5 T 26-04-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A4V04_RS01190 1aeb1486180eef9d0ca300044e4b5832 130 Pfam PF04241 Protein of unknown function (DUF423) 19 106 6.3E-19 T 26-04-2017 IPR006696 Protein of unknown function DUF423 A4V04_RS03740 0783b05f2b443de493f933e245fbb405 332 Pfam PF00535 Glycosyl transferase family 2 66 172 9.4E-24 T 26-04-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4V04_RS03740 0783b05f2b443de493f933e245fbb405 332 Gene3D G3DSA:3.90.550.10 62 327 4.2E-46 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS03740 0783b05f2b443de493f933e245fbb405 332 Pfam PF02709 N-terminal domain of galactosyltransferase 233 297 3.4E-14 T 26-04-2017 IPR027791 Galactosyltransferase, C-terminal A4V04_RS03740 0783b05f2b443de493f933e245fbb405 332 SUPERFAMILY SSF53448 235 305 3.02E-43 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS03740 0783b05f2b443de493f933e245fbb405 332 SUPERFAMILY SSF53448 61 185 3.02E-43 T 26-04-2017 IPR029044 Nucleotide-diphospho-sugar transferases A4V04_RS09985 8298ce856029261c2ee5473a802e1606 298 Gene3D G3DSA:3.40.50.1820 3 292 8.5E-64 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS09985 8298ce856029261c2ee5473a802e1606 298 Pfam PF00561 alpha/beta hydrolase fold 22 277 8.0E-23 T 26-04-2017 IPR000073 Alpha/beta hydrolase fold-1 A4V04_RS09985 8298ce856029261c2ee5473a802e1606 298 SUPERFAMILY SSF53474 1 292 7.28E-57 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS08785 63b7278c407d4e24d18d64f9d6b15ee4 183 Gene3D G3DSA:3.30.70.1300 41 123 6.3E-16 T 26-04-2017 A4V04_RS08785 63b7278c407d4e24d18d64f9d6b15ee4 183 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 1 183 30.938 T 26-04-2017 IPR003774 Protein of unknown function UPF0301 A4V04_RS08785 63b7278c407d4e24d18d64f9d6b15ee4 183 SUPERFAMILY SSF143456 3 176 3.53E-54 T 26-04-2017 A4V04_RS08785 63b7278c407d4e24d18d64f9d6b15ee4 183 Gene3D G3DSA:3.40.1740.10 124 171 5.5E-29 T 26-04-2017 A4V04_RS08785 63b7278c407d4e24d18d64f9d6b15ee4 183 Gene3D G3DSA:3.40.1740.10 3 40 5.5E-29 T 26-04-2017 A4V04_RS08785 63b7278c407d4e24d18d64f9d6b15ee4 183 Pfam PF02622 Uncharacterized ACR, COG1678 12 167 3.0E-40 T 26-04-2017 IPR003774 Protein of unknown function UPF0301 A4V04_RS10910 d86925c8afa18545cc1896cd1fc221e7 240 SUPERFAMILY SSF159888 7 120 1.44E-8 T 26-04-2017 A4V04_RS01205 45a1967c3ea26e4b904addbbf45e7e44 251 SUPERFAMILY SSF53335 84 175 4.39E-15 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS01205 45a1967c3ea26e4b904addbbf45e7e44 251 Pfam PF08241 Methyltransferase domain 79 126 8.1E-10 T 26-04-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A4V04_RS01205 45a1967c3ea26e4b904addbbf45e7e44 251 Gene3D G3DSA:3.40.50.150 27 173 8.8E-16 T 26-04-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4V04_RS06335 9ed434431381517f8ce4f31a022b0d29 824 SUPERFAMILY SSF52540 398 735 8.59E-36 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06335 9ed434431381517f8ce4f31a022b0d29 824 TIGRFAM TIGR00929 VirB4_CagE: type IV secretion/conjugal transfer ATPase, VirB4 family 10 813 5.0E-199 T 26-04-2017 IPR004346 CagE, TrbE, VirB component of type IV transporter system GO:0005524 A4V04_RS06335 9ed434431381517f8ce4f31a022b0d29 824 Gene3D G3DSA:3.40.50.300 452 528 5.9E-15 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06335 9ed434431381517f8ce4f31a022b0d29 824 Gene3D G3DSA:3.40.50.300 595 596 5.9E-15 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06335 9ed434431381517f8ce4f31a022b0d29 824 Gene3D G3DSA:3.40.50.300 651 735 5.9E-15 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06335 9ed434431381517f8ce4f31a022b0d29 824 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 183 383 9.7E-42 T 26-04-2017 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 A4V04_RS10100 e0c0d1847202c6863ef4a5a575c960bd 464 Pfam PF03606 C4-dicarboxylate anaerobic carrier 5 460 2.9E-66 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS10100 e0c0d1847202c6863ef4a5a575c960bd 464 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 58 454 1.0E-91 T 26-04-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A4V04_RS06660 cee37a7039ab07f3846bd80bb0cc0177 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 276 1.9E-36 T 26-04-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A4V04_RS09035 8b1a6412a32813b6680cbb620a074a79 441 SUPERFAMILY SSF56672 7 374 3.34E-51 T 26-04-2017 A4V04_RS09035 8b1a6412a32813b6680cbb620a074a79 441 Pfam PF08388 Group II intron, maturase-specific domain 311 388 1.4E-12 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS09035 8b1a6412a32813b6680cbb620a074a79 441 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 19 375 9.2E-120 T 26-04-2017 IPR030931 Group II intron reverse transcriptase/maturase A4V04_RS09035 8b1a6412a32813b6680cbb620a074a79 441 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 74 283 2.1E-45 T 26-04-2017 IPR000477 Reverse transcriptase domain A4V04_RS08310 5549e20a3942f0cd461e554a9abebb31 103 SUPERFAMILY SSF69754 3 94 1.7E-17 T 26-04-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A4V04_RS08310 5549e20a3942f0cd461e554a9abebb31 103 Gene3D G3DSA:3.30.160.100 4 101 2.1E-17 T 26-04-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A4V04_RS08310 5549e20a3942f0cd461e554a9abebb31 103 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 5 100 6.8E-14 T 26-04-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A4V04_RS06535 138eea2234fc23ae805c5aa7d1310039 279 Pfam PF12784 PD-(D/E)XK nuclease family transposase 34 166 1.8E-13 T 26-04-2017 A4V04_RS05025 dd18aee51d27c7547fe0f123ad158fe5 405 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 19 270 4.3E-57 T 26-04-2017 IPR017039 Virulence factor BrkB A4V04_RS05025 dd18aee51d27c7547fe0f123ad158fe5 405 Pfam PF03631 Virulence factor BrkB 28 270 1.5E-48 T 26-04-2017 IPR017039 Virulence factor BrkB A4V04_RS07060 a92c506192ce2e57af869042936186fd 575 PIRSF PIRSF010386 22 575 1.3E-132 T 26-04-2017 IPR012166 Uncharacterised protein family RocB A4V04_RS07060 a92c506192ce2e57af869042936186fd 575 SUPERFAMILY SSF53187 504 567 8.86E-29 T 26-04-2017 A4V04_RS07060 a92c506192ce2e57af869042936186fd 575 SUPERFAMILY SSF53187 28 257 8.86E-29 T 26-04-2017 A4V04_RS07060 a92c506192ce2e57af869042936186fd 575 Pfam PF01546 Peptidase family M20/M25/M40 107 459 9.1E-11 T 26-04-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4V04_RS07060 a92c506192ce2e57af869042936186fd 575 Gene3D G3DSA:3.40.630.10 29 339 2.2E-37 T 26-04-2017 A4V04_RS09510 52c4916e81588eab94606008ce032891 292 Gene3D G3DSA:1.10.3720.10 11 288 1.2E-44 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS09510 52c4916e81588eab94606008ce032891 292 SUPERFAMILY SSF161098 20 283 2.75E-36 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS09510 52c4916e81588eab94606008ce032891 292 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 9 287 7.4E-85 T 26-04-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 A4V04_RS09510 52c4916e81588eab94606008ce032891 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 285 1.2E-19 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS05640 aea0f95a523a4b54b0838ce6991671c2 684 Gene3D G3DSA:1.10.1370.10 509 681 5.4E-132 T 26-04-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 A4V04_RS05640 aea0f95a523a4b54b0838ce6991671c2 684 Gene3D G3DSA:1.10.1370.10 147 355 5.4E-132 T 26-04-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 A4V04_RS05640 aea0f95a523a4b54b0838ce6991671c2 684 Gene3D G3DSA:1.20.1050.40 19 144 2.4E-20 T 26-04-2017 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal A4V04_RS05640 aea0f95a523a4b54b0838ce6991671c2 684 Gene3D G3DSA:3.40.390.10 366 508 4.9E-55 T 26-04-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A4V04_RS05640 aea0f95a523a4b54b0838ce6991671c2 684 SUPERFAMILY SSF55486 15 680 3.04E-184 T 26-04-2017 A4V04_RS05640 aea0f95a523a4b54b0838ce6991671c2 684 Pfam PF01432 Peptidase family M3 230 680 1.3E-145 T 26-04-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 A4V04_RS00645 3ffdd0d6a8e6ea4cc61a931f5a747199 129 Pfam PF11753 Protein of unknwon function (DUF3310) 6 62 3.4E-18 T 26-04-2017 IPR021739 Protein of unknwon function DUF3310 A4V04_RS02770 14cb1d2813dad5107ed9995a52dcafc5 314 Pfam PF09084 NMT1/THI5 like 54 249 3.1E-21 T 26-04-2017 IPR015168 SsuA/THI5-like A4V04_RS02770 14cb1d2813dad5107ed9995a52dcafc5 314 Gene3D G3DSA:3.40.190.10 117 233 7.5E-21 T 26-04-2017 A4V04_RS02770 14cb1d2813dad5107ed9995a52dcafc5 314 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 30 311 5.7E-51 T 26-04-2017 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 A4V04_RS02770 14cb1d2813dad5107ed9995a52dcafc5 314 SUPERFAMILY SSF53850 26 265 1.96E-37 T 26-04-2017 A4V04_RS07155 cd87d5239cf3bd4bbd0d8a8cdebc1c21 404 Gene3D G3DSA:1.10.443.10 214 379 2.2E-18 T 26-04-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS07155 cd87d5239cf3bd4bbd0d8a8cdebc1c21 404 Pfam PF00589 Phage integrase family 238 372 5.8E-13 T 26-04-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4V04_RS07155 cd87d5239cf3bd4bbd0d8a8cdebc1c21 404 SUPERFAMILY SSF56349 106 383 2.94E-39 T 26-04-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4V04_RS07155 cd87d5239cf3bd4bbd0d8a8cdebc1c21 404 Gene3D G3DSA:1.10.150.130 125 189 4.2E-8 T 26-04-2017 IPR023109 Integrase/recombinase, N-terminal A4V04_RS06365 3f39badf680918daaf37783ced7578fa 118 Pfam PF04221 RelB antitoxin 24 73 1.4E-10 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS06365 3f39badf680918daaf37783ced7578fa 118 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 20 76 1.0E-16 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS00395 ce3a99166dc99d54fb3a59b1a4e20e45 171 Pfam PF00959 Phage lysozyme 44 135 2.7E-14 T 26-04-2017 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 A4V04_RS00395 ce3a99166dc99d54fb3a59b1a4e20e45 171 SUPERFAMILY SSF53955 22 170 1.94E-37 T 26-04-2017 IPR023346 Lysozyme-like domain A4V04_RS00395 ce3a99166dc99d54fb3a59b1a4e20e45 171 Gene3D G3DSA:1.10.530.40 23 170 8.8E-45 T 26-04-2017 IPR023347 Lysozyme domain GO:0003796 A4V04_RS02340 1040775a489292eacd124a9e2b848690 237 Pfam PF01610 Transposase 1 216 3.0E-31 T 26-04-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain A4V04_RS01160 1d44f02fdafdb8b857e11ad141fd968e 171 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 3 117 23.662 T 26-04-2017 IPR026592 Outer membrane protein assembly factor BamE A4V04_RS01160 1d44f02fdafdb8b857e11ad141fd968e 171 Pfam PF04355 SmpA / OmlA family 38 107 1.1E-23 T 26-04-2017 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 A4V04_RS08230 2f560ac029b19b51a7e233a563f95008 424 ProSitePatterns PS01007 Transposases, Mutator family, signature. 254 278 - T 26-04-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4V04_RS08230 2f560ac029b19b51a7e233a563f95008 424 Pfam PF00872 Transposase, Mutator family 36 401 3.5E-110 T 26-04-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4V04_RS07980 547affdcc77806dfacdd690b482ad27a 103 Pfam PF08388 Group II intron, maturase-specific domain 53 95 3.0E-8 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS08755 b00966d299f49b9e8a3ba688d284a27d 331 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 4 328 1.2E-127 T 26-04-2017 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 A4V04_RS08755 b00966d299f49b9e8a3ba688d284a27d 331 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 2 329 53.878 T 26-04-2017 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 A4V04_RS08755 b00966d299f49b9e8a3ba688d284a27d 331 SUPERFAMILY SSF51735 1 328 6.94E-51 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS08755 b00966d299f49b9e8a3ba688d284a27d 331 Gene3D G3DSA:3.90.25.10 171 311 4.1E-32 T 26-04-2017 A4V04_RS08755 b00966d299f49b9e8a3ba688d284a27d 331 Gene3D G3DSA:3.40.50.720 1 170 1.8E-21 T 26-04-2017 IPR016040 NAD(P)-binding domain A4V04_RS08755 b00966d299f49b9e8a3ba688d284a27d 331 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 241 7.0E-42 T 26-04-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4V04_RS07430 69e21cfb149731370b041f86b2bc0b99 349 Pfam PF13515 Fusaric acid resistance protein-like 211 334 1.7E-12 T 26-04-2017 A4V04_RS07765 e35d44ba908b213dc081eecef042505e 207 Gene3D G3DSA:1.10.3820.10 4 184 2.5E-19 T 26-04-2017 A4V04_RS07765 e35d44ba908b213dc081eecef042505e 207 SUPERFAMILY SSF48695 6 185 1.51E-20 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS07765 e35d44ba908b213dc081eecef042505e 207 PIRSF PIRSF000013 1 194 1.2E-26 T 26-04-2017 IPR024717 Denitrification system component NapC/NirT/NrfH GO:0016021|GO:0019333|GO:0020037 A4V04_RS07765 e35d44ba908b213dc081eecef042505e 207 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 4 183 2.6E-34 T 26-04-2017 IPR005126 NapC/NirT cytochrome c, N-terminal A4V04_RS07790 1095344915bb715175177350ecbc0ce8 216 SUPERFAMILY SSF53271 10 214 4.2E-66 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS07790 1095344915bb715175177350ecbc0ce8 216 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 10 216 1.6E-80 T 26-04-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A4V04_RS07790 1095344915bb715175177350ecbc0ce8 216 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 9 216 44.439 T 26-04-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A4V04_RS07790 1095344915bb715175177350ecbc0ce8 216 Gene3D G3DSA:3.40.50.2020 9 216 4.0E-77 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS07790 1095344915bb715175177350ecbc0ce8 216 Pfam PF14681 Uracil phosphoribosyltransferase 13 215 2.1E-72 T 26-04-2017 IPR029057 Phosphoribosyltransferase-like A4V04_RS12720 ced68aade39aa8008c5bcd124d68ee39 60 Pfam PF08011 PD-(D/E)XK nuclease superfamily 1 54 4.1E-6 T 26-04-2017 IPR012547 PD-(D/E)XK nuclease superfamily 9 A4V04_RS08925 528b0cc41e756207d607d1b7c31b5e45 80 Gene3D G3DSA:2.20.28.30 5 40 4.2E-4 T 26-04-2017 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A4V04_RS08925 528b0cc41e756207d607d1b7c31b5e45 80 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 2.9E-22 T 26-04-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A4V04_RS08925 528b0cc41e756207d607d1b7c31b5e45 80 SMART SM00834 1 42 9.8E-20 T 26-04-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A4V04_RS08925 528b0cc41e756207d607d1b7c31b5e45 80 Pfam PF09723 Zinc ribbon domain 1 40 9.1E-17 T 26-04-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A4V04_RS01705 b3a24b7deb17b498c5c11fe42fa027c0 302 Pfam PF03773 Predicted permease 9 298 8.7E-50 T 26-04-2017 IPR005524 Predicted permease DUF318 A4V04_RS05200 c3450a7682eac50f2b3ebe6135d1a398 75 Pfam PF04023 FeoA domain 1 68 3.3E-14 T 26-04-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A4V04_RS05200 c3450a7682eac50f2b3ebe6135d1a398 75 SMART SM00899 1 74 2.0E-17 T 26-04-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A4V04_RS05200 c3450a7682eac50f2b3ebe6135d1a398 75 SUPERFAMILY SSF50037 5 74 4.58E-16 T 26-04-2017 IPR008988 Transcriptional repressor, C-terminal A4V04_RS07090 9dabf3f6f9ea34d95f71ff75e13e2162 421 Pfam PF03606 C4-dicarboxylate anaerobic carrier 49 419 1.3E-18 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS00850 20d427788a3d85693084c1e2a8e208c2 77 Gene3D G3DSA:2.30.170.40 2 76 2.2E-38 T 26-04-2017 A4V04_RS00850 20d427788a3d85693084c1e2a8e208c2 77 SUPERFAMILY SSF143800 2 74 7.26E-32 T 26-04-2017 A4V04_RS00850 20d427788a3d85693084c1e2a8e208c2 77 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 21.747 T 26-04-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS00850 20d427788a3d85693084c1e2a8e208c2 77 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 2.6E-27 T 26-04-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4V04_RS00850 20d427788a3d85693084c1e2a8e208c2 77 Pfam PF00830 Ribosomal L28 family 3 62 5.4E-29 T 26-04-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS02060 40d5c2f403c7ae1fa94cb0b577e0a3ce 578 Pfam PF03050 Transposase IS66 family 160 470 8.1E-30 T 26-04-2017 IPR004291 Transposase, IS66 A4V04_RS06495 9743c6677162730e8266d483c5ab4ed6 258 Pfam PF13707 RloB-like protein 57 243 1.1E-31 T 26-04-2017 IPR025591 RloB-like protein A4V04_RS01115 ea752ecbbca579a28c066363fafd495a 101 ProDom PD015450 MALONATE DECARBOXYLASE SUBUNIT DELTA ACYL CARRIER DECARBOXYLASE PLASMID DIRECT SEQUENCING 1 96 1.0E-21 T 26-04-2017 IPR009662 Malonate decarboxylase delta subunit A4V04_RS01115 ea752ecbbca579a28c066363fafd495a 101 TIGRFAM TIGR03130 malonate_delta: malonate decarboxylase acyl carrier protein 3 97 1.5E-25 T 26-04-2017 IPR009662 Malonate decarboxylase delta subunit A4V04_RS01115 ea752ecbbca579a28c066363fafd495a 101 Hamap MF_00710 Malonate decarboxylase acyl carrier protein [mdcC]. 1 101 34.684 T 26-04-2017 IPR009662 Malonate decarboxylase delta subunit A4V04_RS01115 ea752ecbbca579a28c066363fafd495a 101 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 20 97 1.1E-19 T 26-04-2017 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein A4V04_RS07340 91d0d1e1499b8b8b868e6fc5d9fad2a8 161 Pfam PF04306 Protein of unknown function (DUF456) 23 158 5.8E-33 T 26-04-2017 IPR007403 Protein of unknown function DUF456 A4V04_RS07120 81fb19eb59bc9b2e9ee25b70d3195687 236 Pfam PF04402 Protein of unknown function (DUF541) 40 209 1.1E-17 T 26-04-2017 IPR007497 Protein of unknown function DUF541 A4V04_RS07120 81fb19eb59bc9b2e9ee25b70d3195687 236 PIRSF PIRSF029033 1 236 1.2E-79 T 26-04-2017 IPR016907 Uncharacterised conserved protein UCP029033, periplasmic protein A4V04_RS07080 e42943eddcb367d6d2bdca6ca627421d 119 SUPERFAMILY SSF50891 4 112 1.63E-17 T 26-04-2017 IPR029000 Cyclophilin-like domain A4V04_RS08290 6dea721a10db91d0322a9dc63b6efadc 142 SUPERFAMILY SSF52161 1 139 1.7E-59 T 26-04-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4V04_RS08290 6dea721a10db91d0322a9dc63b6efadc 142 Gene3D G3DSA:3.90.1180.10 3 141 5.2E-62 T 26-04-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4V04_RS08290 6dea721a10db91d0322a9dc63b6efadc 142 PIRSF PIRSF002181 1 142 1.0E-48 T 26-04-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4V04_RS08290 6dea721a10db91d0322a9dc63b6efadc 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 27.562 T 26-04-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4V04_RS08290 6dea721a10db91d0322a9dc63b6efadc 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 6 141 3.2E-60 T 26-04-2017 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4V04_RS08290 6dea721a10db91d0322a9dc63b6efadc 142 Pfam PF00572 Ribosomal protein L13 14 138 1.3E-54 T 26-04-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4V04_RS12180 da3f73eadf074bca6527f31e1691819f 243 Pfam PF00005 ABC transporter 26 171 4.9E-26 T 26-04-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4V04_RS12180 da3f73eadf074bca6527f31e1691819f 243 SMART SM00382 33 214 1.1E-7 T 26-04-2017 IPR003593 AAA+ ATPase domain A4V04_RS12180 da3f73eadf074bca6527f31e1691819f 243 SUPERFAMILY SSF52540 7 220 1.02E-45 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12180 da3f73eadf074bca6527f31e1691819f 243 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 26-04-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4V04_RS12180 da3f73eadf074bca6527f31e1691819f 243 Gene3D G3DSA:3.40.50.300 7 218 7.4E-48 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS12645 6f657220e59f59d5c6cd19a6f29f3e54 169 Pfam PF05433 Glycine zipper 2TM domain 71 109 4.1E-7 T 26-04-2017 IPR008816 Glycine zipper 2TM domain GO:0019867 A4V04_RS12380 222007a106d76da5fd718588178972b4 383 Pfam PF03060 Nitronate monooxygenase 47 374 6.8E-36 T 26-04-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4V04_RS12380 222007a106d76da5fd718588178972b4 383 SUPERFAMILY SSF51412 46 380 2.75E-26 T 26-04-2017 A4V04_RS12380 222007a106d76da5fd718588178972b4 383 Gene3D G3DSA:3.20.20.70 46 320 8.9E-23 T 26-04-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 A4V04_RS13155 4993119f925bce52b1ef62a8ba2c3ddb 85 Gene3D G3DSA:2.30.170.10 49 74 6.5E-5 T 26-04-2017 A4V04_RS13155 4993119f925bce52b1ef62a8ba2c3ddb 85 Pfam PF02069 Prokaryotic metallothionein 49 74 3.2E-5 T 26-04-2017 IPR000518 Metallothionein, family 14, prokaryote GO:0046872 A4V04_RS08340 38f793a33526ca7b1a8e51814982f467 378 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 373 4.6E-94 T 26-04-2017 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 A4V04_RS08340 38f793a33526ca7b1a8e51814982f467 378 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 372 2.9E-60 T 26-04-2017 IPR005495 Permease LptG/LptF-related GO:0016021 A4V04_RS04315 d97751ce00f20d024957762ec080ebff 164 Pfam PF05981 CreA protein 28 150 8.5E-40 T 26-04-2017 IPR010292 Uncharacterised protein family CreA A4V04_RS09460 1e693645c879cffdd822ec82ec16bea1 145 SMART SM00450 34 129 2.5E-21 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS09460 1e693645c879cffdd822ec82ec16bea1 145 Pfam PF00581 Rhodanese-like domain 35 126 1.4E-16 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS09460 1e693645c879cffdd822ec82ec16bea1 145 SUPERFAMILY SSF52821 29 132 3.27E-30 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS09460 1e693645c879cffdd822ec82ec16bea1 145 Gene3D G3DSA:3.40.250.10 27 132 1.6E-29 T 26-04-2017 IPR001763 Rhodanese-like domain A4V04_RS08795 17064fed9c4af93ad31c0f35a0fc5b61 145 Pfam PF11026 Protein of unknown function (DUF2721) 11 135 5.5E-31 T 26-04-2017 IPR021279 Protein of unknown function DUF2721 A4V04_RS04900 f4c40d14409c57b27e98a636e6f08d30 138 Pfam PF03724 META domain 44 128 7.6E-17 T 26-04-2017 IPR005184 Domain of unknown function DUF306, Meta/HslJ A4V04_RS05535 9d82de4deee8c20eea4eb2f71562b35f 380 SUPERFAMILY SSF52540 19 141 2.18E-14 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS05535 9d82de4deee8c20eea4eb2f71562b35f 380 Pfam PF13173 AAA domain 19 140 6.5E-23 T 26-04-2017 A4V04_RS05535 9d82de4deee8c20eea4eb2f71562b35f 380 Pfam PF13635 Domain of unknown function (DUF4143) 186 344 4.0E-20 T 26-04-2017 IPR025420 Domain of unknown function DUF4143 A4V04_RS05535 9d82de4deee8c20eea4eb2f71562b35f 380 Gene3D G3DSA:3.40.50.300 11 111 3.4E-6 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02170 dc129c9719c54ec9d638a637f9c7a429 538 SUPERFAMILY SSF52540 10 336 1.32E-15 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02170 dc129c9719c54ec9d638a637f9c7a429 538 Gene3D G3DSA:3.40.50.300 10 117 3.9E-22 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02170 dc129c9719c54ec9d638a637f9c7a429 538 Gene3D G3DSA:3.40.50.300 170 355 3.9E-22 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS02170 dc129c9719c54ec9d638a637f9c7a429 538 Pfam PF13175 AAA ATPase domain 10 333 8.9E-19 T 26-04-2017 A4V04_RS10175 0750e6e4497d7324bd320305eefefd7e 422 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 63 415 1.1E-56 T 26-04-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A4V04_RS10175 0750e6e4497d7324bd320305eefefd7e 422 Pfam PF03606 C4-dicarboxylate anaerobic carrier 67 419 7.0E-21 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS04505 3f43d60d5b6cf8bb9b3384f783ee152e 185 Gene3D G3DSA:2.10.109.10 81 184 9.6E-14 T 26-04-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain A4V04_RS04505 3f43d60d5b6cf8bb9b3384f783ee152e 185 SUPERFAMILY SSF51306 82 182 5.58E-12 T 26-04-2017 IPR015927 Peptidase S24/S26A/S26B/S26C A4V04_RS11610 934d294f87c1a47d8281b31dce6ea363 226 Pfam PF01618 MotA/TolQ/ExbB proton channel family 81 212 3.4E-40 T 26-04-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 A4V04_RS11610 934d294f87c1a47d8281b31dce6ea363 226 TIGRFAM TIGR02796 tolQ: protein TolQ 8 224 1.8E-85 T 26-04-2017 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 A4V04_RS00725 51a03b796ca74763000c0e1aca082291 154 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 9 146 1.3E-20 T 26-04-2017 IPR009936 Protein of unknown function DUF1468 A4V04_RS10810 e82f46b73ecd032efcd92e827ed67200 324 SUPERFAMILY SSF53850 162 283 5.65E-9 T 26-04-2017 A4V04_RS10810 e82f46b73ecd032efcd92e827ed67200 324 PIRSF PIRSF017082 1 324 1.0E-64 T 26-04-2017 IPR005064 Bordetella uptake gene GO:0030288 A4V04_RS10810 e82f46b73ecd032efcd92e827ed67200 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 319 4.7E-57 T 26-04-2017 IPR005064 Bordetella uptake gene GO:0030288 A4V04_RS10590 2f5b9ae6ff53950c19f910aa8c546c8b 324 Pfam PF03547 Membrane transport protein 18 156 7.2E-15 T 26-04-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A4V04_RS10590 2f5b9ae6ff53950c19f910aa8c546c8b 324 Pfam PF03547 Membrane transport protein 165 312 1.4E-14 T 26-04-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A4V04_RS02590 434be492207e7d00b6fe202a2843a093 88 SUPERFAMILY SSF143011 1 88 3.34E-21 T 26-04-2017 A4V04_RS02590 434be492207e7d00b6fe202a2843a093 88 PIRSF PIRSF006156 1 88 1.5E-21 T 26-04-2017 IPR004386 Toxin-antitoxin system, YafQ-like toxin A4V04_RS02590 434be492207e7d00b6fe202a2843a093 88 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 7 88 6.4E-19 T 26-04-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4V04_RS02590 434be492207e7d00b6fe202a2843a093 88 Pfam PF15738 Bacterial toxin of type II toxin-antitoxin system, YafQ 4 88 1.1E-27 T 26-04-2017 IPR004386 Toxin-antitoxin system, YafQ-like toxin A4V04_RS05920 0ede44a89562babfa2dd68f619ee8353 321 Pfam PF03547 Membrane transport protein 6 155 2.4E-22 T 26-04-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A4V04_RS05920 0ede44a89562babfa2dd68f619ee8353 321 Pfam PF03547 Membrane transport protein 167 311 1.6E-18 T 26-04-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A4V04_RS06010 e3f8bfb3e93963cb380a511686837011 140 ProDom PD075772 YGBA ECS3588 CYTOPLASMIC UVRA STM2860 AMIDOPHOSPHORIBOSYLTRANSFERASE VVA0912 SO0324 VPA0976 CPE0229 24 116 4.0E-22 T 26-04-2017 IPR020483 Uncharacterised protein family YgbA A4V04_RS06010 e3f8bfb3e93963cb380a511686837011 140 Pfam PF11756 Nitrous oxide-stimulated promoter 25 125 6.1E-35 T 26-04-2017 IPR020483 Uncharacterised protein family YgbA A4V04_RS00610 322fbe48eaf7a8030875cc6a4aeb53f4 175 Pfam PF09669 Phage regulatory protein Rha (Phage_pRha) 23 110 2.1E-27 T 26-04-2017 IPR014054 Bacteriophage regulatory protein, Rha family A4V04_RS00610 322fbe48eaf7a8030875cc6a4aeb53f4 175 TIGRFAM TIGR02681 phage_pRha: phage regulatory protein, Rha family 13 115 7.1E-30 T 26-04-2017 IPR014054 Bacteriophage regulatory protein, Rha family A4V04_RS00610 322fbe48eaf7a8030875cc6a4aeb53f4 175 Pfam PF10549 ORF11CD3 domain 122 171 5.5E-7 T 26-04-2017 IPR018877 Bacteriophage P22, Orf201, C-terminal A4V04_RS09150 b5720f57a5aa6076c922c4007d889701 384 Gene3D G3DSA:2.40.160.10 26 384 6.3E-49 T 26-04-2017 IPR023614 Porin domain A4V04_RS09150 b5720f57a5aa6076c922c4007d889701 384 Pfam PF13609 Gram-negative porin 17 352 2.1E-28 T 26-04-2017 A4V04_RS09150 b5720f57a5aa6076c922c4007d889701 384 SUPERFAMILY SSF56935 26 384 3.05E-36 T 26-04-2017 A4V04_RS03205 414e6e913835b4463957960098bd3eb2 107 Hamap MF_00599 Cell division protein FtsB [ftsB]. 14 102 22.345 T 26-04-2017 IPR023081 Cell division protein FtsB A4V04_RS03205 414e6e913835b4463957960098bd3eb2 107 Pfam PF04977 Septum formation initiator 23 101 1.8E-17 T 26-04-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 A4V04_RS13150 6c7bb7c67e1f7a8d2ec759fbff752124 275 Pfam PF01578 Cytochrome C assembly protein 63 273 2.9E-30 T 26-04-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A4V04_RS02190 56cb59deb34c4f11fe894619521d12c4 105 Pfam PF07751 Abi-like protein 39 104 5.0E-18 T 26-04-2017 IPR011664 Abortive infection system protein AbiD/AbiF-like A4V04_RS03835 8eb0944f499efc9c14ce6080977c3b10 249 Pfam PF04402 Protein of unknown function (DUF541) 35 238 7.1E-18 T 26-04-2017 IPR007497 Protein of unknown function DUF541 A4V04_RS11010 a9ecf2a66a45bd092dcef3713c344e29 137 SUPERFAMILY SSF46955 7 72 9.61E-12 T 26-04-2017 IPR009061 Putative DNA-binding domain A4V04_RS11010 a9ecf2a66a45bd092dcef3713c344e29 137 Gene3D G3DSA:1.10.1660.10 7 120 1.2E-12 T 26-04-2017 A4V04_RS11010 a9ecf2a66a45bd092dcef3713c344e29 137 Pfam PF13411 MerR HTH family regulatory protein 8 70 5.2E-15 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS11010 a9ecf2a66a45bd092dcef3713c344e29 137 SMART SM00422 7 75 2.0E-4 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS12460 e789549428b789d035b1e61ea4e01665 310 Gene3D G3DSA:1.10.10.60 240 298 2.9E-12 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS12460 e789549428b789d035b1e61ea4e01665 310 SUPERFAMILY SSF46689 241 296 5.38E-8 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS12460 e789549428b789d035b1e61ea4e01665 310 Pfam PF12833 Helix-turn-helix domain 213 292 7.5E-14 T 26-04-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4V04_RS12460 e789549428b789d035b1e61ea4e01665 310 SMART SM00342 206 291 1.5E-14 T 26-04-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4V04_RS12460 e789549428b789d035b1e61ea4e01665 310 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 242 287 - T 26-04-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4V04_RS07770 2f68def99b9b39e5597adfb80bce18af 476 Pfam PF03577 Peptidase family C69 2 398 3.8E-113 T 26-04-2017 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 A4V04_RS06510 50521275bb62e68f8bd3898a723b41d9 307 Gene3D G3DSA:3.40.50.300 1 251 3.4E-30 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06510 50521275bb62e68f8bd3898a723b41d9 307 SUPERFAMILY SSF52540 1 256 1.01E-27 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS06510 50521275bb62e68f8bd3898a723b41d9 307 Pfam PF13614 AAA domain 1 172 9.1E-26 T 26-04-2017 IPR025669 AAA domain A4V04_RS00790 f6d34892a548eadd1b51f45592565608 137 Pfam PF02643 Uncharacterized ACR, COG1430 32 133 6.7E-35 T 26-04-2017 IPR003795 Protein of unknown function DUF192 A4V04_RS07825 e90d1601e85811d070da60cb9f613928 103 SUPERFAMILY SSF48695 30 96 3.67E-12 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS07825 e90d1601e85811d070da60cb9f613928 103 Gene3D G3DSA:4.10.1020.10 32 96 6.8E-16 T 26-04-2017 IPR027406 Periplasmic nitrate reductase NapB subunit, heme binding domain A4V04_RS07825 e90d1601e85811d070da60cb9f613928 103 Pfam PF03892 Nitrate reductase cytochrome c-type subunit (NapB) 26 97 1.0E-13 T 26-04-2017 IPR005591 Nitrate reductase cytochrome c-type subunit NapB A4V04_RS02305 79062b46628cd8f37fe0432463361913 67 Pfam PF14487 Domain of unknown function (DUF4433) 10 65 1.2E-12 T 26-04-2017 IPR029494 Domain of unknown function DUF4433 A4V04_RS11855 9579dd154b6ec6609564cae5c8127384 256 Pfam PF02361 Cobalt transport protein 11 210 1.2E-18 T 26-04-2017 IPR003339 ABC/ECF transporter, transmembrane component A4V04_RS06530 d6802d6a141cd1a38171a1bfb98b8a91 27 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 5 25 2.7E-4 T 26-04-2017 IPR009614 Toxin YoeB GO:0004519|GO:0006401 A4V04_RS09025 4e8018bd35a88044a3c38168c9163634 158 SUPERFAMILY SSF55804 3 147 6.41E-34 T 26-04-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A4V04_RS09025 4e8018bd35a88044a3c38168c9163634 158 Gene3D G3DSA:3.40.930.10 1 148 2.0E-38 T 26-04-2017 IPR002178 PTS EIIA type-2 domain A4V04_RS09025 4e8018bd35a88044a3c38168c9163634 158 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 147 1.6E-29 T 26-04-2017 IPR002178 PTS EIIA type-2 domain A4V04_RS02395 d25cf5db9ed54934a277747342569882 395 Pfam PF09820 Predicted AAA-ATPase 10 286 1.2E-72 T 26-04-2017 IPR018631 AAA-ATPase-like domain A4V04_RS12175 1b9b1aa2fcafdb2603b4d4d9de6641c0 238 Pfam PF02361 Cobalt transport protein 8 210 1.4E-26 T 26-04-2017 IPR003339 ABC/ECF transporter, transmembrane component A4V04_RS01270 a37006fcc1c63655995852c9086ac29f 257 SUPERFAMILY SSF53474 32 256 7.3E-19 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS01270 a37006fcc1c63655995852c9086ac29f 257 Gene3D G3DSA:3.40.50.1820 32 247 6.6E-16 T 26-04-2017 IPR029058 Alpha/Beta hydrolase fold A4V04_RS13090 07c5e643329ab6beee24e465039409f0 240 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 34 237 8.2E-25 T 26-04-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 A4V04_RS13090 07c5e643329ab6beee24e465039409f0 240 Gene3D G3DSA:3.40.190.10 113 192 4.1E-18 T 26-04-2017 A4V04_RS13090 07c5e643329ab6beee24e465039409f0 240 Gene3D G3DSA:3.40.190.10 20 112 5.1E-7 T 26-04-2017 A4V04_RS13090 07c5e643329ab6beee24e465039409f0 240 Gene3D G3DSA:3.40.190.10 199 235 5.1E-7 T 26-04-2017 A4V04_RS13090 07c5e643329ab6beee24e465039409f0 240 SUPERFAMILY SSF53850 20 237 3.88E-34 T 26-04-2017 A4V04_RS13090 07c5e643329ab6beee24e465039409f0 240 Pfam PF13531 Bacterial extracellular solute-binding protein 22 238 7.4E-26 T 26-04-2017 A4V04_RS04165 156a4b038e5942ee8c5f0e66910ce106 183 Pfam PF02632 BioY family 37 177 1.7E-33 T 26-04-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A4V04_RS04165 156a4b038e5942ee8c5f0e66910ce106 183 PIRSF PIRSF016661 2 183 3.8E-39 T 26-04-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A4V04_RS05145 4138232a38e652d2791b9824affe7ee5 226 Pfam PF07813 LTXXQ motif family protein 100 182 3.6E-10 T 26-04-2017 IPR012899 LTXXQ motif family protein GO:0042597 A4V04_RS03330 35d13ad96b5528e41b2a813119bd00b0 202 Pfam PF00565 Staphylococcal nuclease homologue 79 185 1.5E-18 T 26-04-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold A4V04_RS03330 35d13ad96b5528e41b2a813119bd00b0 202 SMART SM00318 52 185 2.8E-19 T 26-04-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold A4V04_RS03330 35d13ad96b5528e41b2a813119bd00b0 202 Gene3D G3DSA:2.40.50.90 54 192 1.5E-30 T 26-04-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold A4V04_RS03330 35d13ad96b5528e41b2a813119bd00b0 202 SUPERFAMILY SSF50199 52 192 4.18E-33 T 26-04-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold A4V04_RS13165 bf87348ac5f4e137aafbd58107aafcde 176 Pfam PF02325 YGGT family 104 170 1.2E-9 T 26-04-2017 IPR003425 CCB3/YggT GO:0016020 A4V04_RS13165 bf87348ac5f4e137aafbd58107aafcde 176 Pfam PF02325 YGGT family 12 79 1.0E-6 T 26-04-2017 IPR003425 CCB3/YggT GO:0016020 A4V04_RS03405 eee049ac0690f2f157052370dc9c2649 272 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 11 259 8.7E-58 T 26-04-2017 IPR005226 UPF0014 family A4V04_RS03405 eee049ac0690f2f157052370dc9c2649 272 Pfam PF03649 Uncharacterised protein family (UPF0014) 13 257 3.9E-71 T 26-04-2017 IPR005226 UPF0014 family A4V04_RS12900 2eb8c7160024cfd4e4e8d1260fcdbafe 161 Pfam PF01878 EVE domain 9 152 1.7E-46 T 26-04-2017 IPR002740 EVE domain A4V04_RS12900 2eb8c7160024cfd4e4e8d1260fcdbafe 161 SUPERFAMILY SSF88697 7 154 2.57E-50 T 26-04-2017 IPR015947 PUA-like domain A4V04_RS12900 2eb8c7160024cfd4e4e8d1260fcdbafe 161 Gene3D G3DSA:3.10.590.10 9 153 2.1E-26 T 26-04-2017 IPR002740 EVE domain A4V04_RS07865 31cba98ae5c1bc3cca06862c8de748b5 281 Pfam PF01969 Protein of unknown function DUF111 45 270 2.7E-57 T 26-04-2017 IPR002822 Uncharacterised protein family UPF0272 A4V04_RS00445 3347b9cb56382b21018ee3a2af14b579 351 SUPERFAMILY SSF88874 151 252 1.83E-6 T 26-04-2017 A4V04_RS00445 3347b9cb56382b21018ee3a2af14b579 351 SUPERFAMILY SSF88874 300 349 1.83E-6 T 26-04-2017 A4V04_RS10805 daadf367a050760bc4e808a086904091 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 2.2E-10 T 26-04-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4V04_RS10805 daadf367a050760bc4e808a086904091 208 SUPERFAMILY SSF46689 4 86 1.59E-16 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS10805 daadf367a050760bc4e808a086904091 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 8.1E-5 T 26-04-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4V04_RS10805 daadf367a050760bc4e808a086904091 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 8.1E-5 T 26-04-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4V04_RS10805 daadf367a050760bc4e808a086904091 208 Gene3D G3DSA:1.10.357.10 60 200 1.5E-17 T 26-04-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4V04_RS10805 daadf367a050760bc4e808a086904091 208 Gene3D G3DSA:1.10.10.60 5 59 3.4E-18 T 26-04-2017 IPR009057 Homeodomain-like GO:0003677 A4V04_RS01345 3359d327424090be7a38bb1cbc9949e3 375 SUPERFAMILY SSF53383 16 373 3.03E-90 T 26-04-2017 IPR015424 Pyridoxal phosphate-dependent transferase A4V04_RS01345 3359d327424090be7a38bb1cbc9949e3 375 Gene3D G3DSA:3.90.1150.10 253 374 1.3E-32 T 26-04-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4V04_RS01345 3359d327424090be7a38bb1cbc9949e3 375 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 17 369 5.9E-93 T 26-04-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4V04_RS01345 3359d327424090be7a38bb1cbc9949e3 375 Gene3D G3DSA:3.40.640.10 16 250 3.6E-65 T 26-04-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4V04_RS01345 3359d327424090be7a38bb1cbc9949e3 375 PIRSF PIRSF000390 3 374 1.6E-84 T 26-04-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4V04_RS11185 2d20fc822601602d5795feeded39aadb 673 Pfam PF03050 Transposase IS66 family 271 585 5.0E-29 T 26-04-2017 IPR004291 Transposase, IS66 A4V04_RS04130 fa09efe6f25d7bc575166756079eb810 117 Pfam PF05717 IS66 Orf2 like protein 10 109 6.5E-16 T 26-04-2017 IPR008878 Transposase IS66, Orf2 A4V04_RS12570 275bb7df0da6468e02afbb68f63cf2fc 78 Pfam PF02416 mttA/Hcf106 family 5 53 4.5E-15 T 26-04-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A4V04_RS12570 275bb7df0da6468e02afbb68f63cf2fc 78 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 77 23.401 T 26-04-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A4V04_RS12570 275bb7df0da6468e02afbb68f63cf2fc 78 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 49 1.9E-23 T 26-04-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A4V04_RS10160 3e8ebeb6187db15594a391768ea8a472 410 PRINTS PR00173 Glutamate-aspartate symporter signature 331 350 1.7E-25 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS10160 3e8ebeb6187db15594a391768ea8a472 410 PRINTS PR00173 Glutamate-aspartate symporter signature 8 28 1.7E-25 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS10160 3e8ebeb6187db15594a391768ea8a472 410 PRINTS PR00173 Glutamate-aspartate symporter signature 144 166 1.7E-25 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS10160 3e8ebeb6187db15594a391768ea8a472 410 PRINTS PR00173 Glutamate-aspartate symporter signature 50 70 1.7E-25 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS10160 3e8ebeb6187db15594a391768ea8a472 410 PRINTS PR00173 Glutamate-aspartate symporter signature 194 213 1.7E-25 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS10160 3e8ebeb6187db15594a391768ea8a472 410 PRINTS PR00173 Glutamate-aspartate symporter signature 296 322 1.7E-25 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS10160 3e8ebeb6187db15594a391768ea8a472 410 SUPERFAMILY SSF118215 18 403 4.71E-84 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS10160 3e8ebeb6187db15594a391768ea8a472 410 Pfam PF00375 Sodium:dicarboxylate symporter family 17 403 1.1E-91 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS10160 3e8ebeb6187db15594a391768ea8a472 410 Gene3D G3DSA:1.10.3860.10 11 403 1.8E-88 T 26-04-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4V04_RS11210 2b148e3dc5fccff12dc652ff9f9092ae 97 Pfam PF14537 Cytochrome c3 29 97 2.3E-14 T 26-04-2017 A4V04_RS11210 2b148e3dc5fccff12dc652ff9f9092ae 97 Gene3D G3DSA:3.90.10.10 14 96 6.0E-10 T 26-04-2017 A4V04_RS11210 2b148e3dc5fccff12dc652ff9f9092ae 97 SUPERFAMILY SSF48695 19 96 2.68E-10 T 26-04-2017 IPR011031 Multihaem cytochrome A4V04_RS10990 1d1943348d26f4b433da0fa7a0563691 188 Pfam PF11937 Protein of unknown function (DUF3455) 108 188 1.6E-12 T 26-04-2017 IPR021851 Protein of unknown function DUF3455 A4V04_RS08800 0179f50d31f8023649b6f75fe918a5f5 188 Pfam PF03729 Short repeat of unknown function (DUF308) 74 142 8.6E-6 T 26-04-2017 IPR005325 Protein of unknown function DUF308, membrane A4V04_RS08800 0179f50d31f8023649b6f75fe918a5f5 188 Pfam PF03729 Short repeat of unknown function (DUF308) 20 88 6.9E-8 T 26-04-2017 IPR005325 Protein of unknown function DUF308, membrane A4V04_RS01760 95cb0211cedf283af9c48bac8e767640 453 Pfam PF06122 Conjugative relaxosome accessory transposon protein 1 366 2.9E-79 T 26-04-2017 IPR010927 Type IV conjugative transfer system protein TraH A4V04_RS12195 97e61c7c9b15507b47c727c0effd3df6 456 Pfam PF03606 C4-dicarboxylate anaerobic carrier 4 453 1.2E-66 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS12195 97e61c7c9b15507b47c727c0effd3df6 456 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 61 445 2.7E-88 T 26-04-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A4V04_RS06025 696d07560581849762f3d05d173ab1c1 75 SUPERFAMILY SSF50037 5 74 1.3E-16 T 26-04-2017 IPR008988 Transcriptional repressor, C-terminal A4V04_RS06025 696d07560581849762f3d05d173ab1c1 75 SMART SM00899 1 74 1.4E-19 T 26-04-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A4V04_RS06025 696d07560581849762f3d05d173ab1c1 75 Pfam PF04023 FeoA domain 1 67 1.8E-13 T 26-04-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A4V04_RS06525 4c8fe2784f22cd58d8fabaace2af03bd 88 Pfam PF04221 RelB antitoxin 6 53 2.7E-13 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS06525 4c8fe2784f22cd58d8fabaace2af03bd 88 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 1 59 4.1E-16 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS10800 cb777abd0effd568e42239211986607b 215 Pfam PF01914 MarC family integral membrane protein 8 211 5.6E-50 T 26-04-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A4V04_RS10800 cb777abd0effd568e42239211986607b 215 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 7 208 1.2E-40 T 26-04-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A4V04_RS11450 d5baf00126fad0777db07c7bfceac7c7 392 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 157 376 6.1E-16 T 26-04-2017 IPR005079 Peptidase C45 A4V04_RS11450 d5baf00126fad0777db07c7bfceac7c7 392 Pfam PF15508 beta subunit of N-acylethanolamine-hydrolyzing acid amidase 48 136 1.1E-6 T 26-04-2017 IPR029130 Acid ceramidase, N-terminal A4V04_RS11810 14f13a0e52f318ca3592649bed201ebb 60 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 1 51 3.2E-13 T 26-04-2017 IPR009241 Toxin HigB-like A4V04_RS04435 76d73d80c5868a2d20dd4229d5f86502 124 Pfam PF16762 Ribbon-helix-helix domain 4 73 7.6E-18 T 26-04-2017 IPR031914 XACb0070, ribbon-helix-helix domain A4V04_RS02580 e3e516acfede19bef6fe24404a8f8083 512 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 21 1.1E-10 T 26-04-2017 IPR024973 ESPR domain A4V04_RS00160 8074607d18996dfdb32b63e737d55f69 131 SUPERFAMILY SSF46955 17 127 1.1E-12 T 26-04-2017 IPR009061 Putative DNA-binding domain A4V04_RS00160 8074607d18996dfdb32b63e737d55f69 131 SMART SM00422 17 86 8.9E-4 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS00160 8074607d18996dfdb32b63e737d55f69 131 Gene3D G3DSA:1.10.1660.10 17 127 9.6E-13 T 26-04-2017 A4V04_RS00160 8074607d18996dfdb32b63e737d55f69 131 Pfam PF13411 MerR HTH family regulatory protein 17 83 3.7E-17 T 26-04-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4V04_RS00355 740b862609153e64db82f484d8895de7 75 SUPERFAMILY SSF89447 9 50 9.77E-5 T 26-04-2017 A4V04_RS02035 bc570627cb3b0a4576f3a2dedf538c5d 118 Pfam PF05717 IS66 Orf2 like protein 10 109 2.8E-16 T 26-04-2017 IPR008878 Transposase IS66, Orf2 A4V04_RS10630 70a03456ba3947de6c38277f377bdcb4 365 Pfam PF02405 Permease MlaE 154 358 4.5E-61 T 26-04-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 A4V04_RS03450 8dbcde6135d2d36c14fda22cdf9590e4 139 Pfam PF08863 YolD-like protein 51 128 1.0E-8 T 26-04-2017 IPR014962 YolD-like protein A4V04_RS00435 0c652ca36e0332ecf260dcdee41cbd0b 99 Pfam PF13876 Phage protein (N4 Gp49/phage Sf6 gene 66) family 19 89 2.4E-19 T 26-04-2017 IPR025915 Phage protein (N4 Gp49/phage Sf6 gene 66) family A4V04_RS12165 696859f17a9d389124d2de68d5c5d269 202 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 192 1.6E-45 T 26-04-2017 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 A4V04_RS02625 48bc6ab4060d0c27edc0404f562fc298 726 Pfam PF11874 Domain of unknown function (DUF3394) 630 683 5.1E-9 T 26-04-2017 IPR021814 Protein of unknown function DUF3394 A4V04_RS02625 48bc6ab4060d0c27edc0404f562fc298 726 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 165 616 8.0E-74 T 26-04-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A4V04_RS02625 48bc6ab4060d0c27edc0404f562fc298 726 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 56 677 8.4E-188 T 26-04-2017 IPR011853 TRAP transporter, 4TM/12TM fusion protein A4V04_RS11370 a62ae0b1fe3185156fdae3eccbc8f29c 110 SUPERFAMILY SSF51206 40 102 3.66E-5 T 26-04-2017 IPR018490 Cyclic nucleotide-binding-like A4V04_RS03185 4642b0bf8c8cd62d5db9b24391f4b905 195 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 8 177 1.0E-45 T 26-04-2017 IPR006287 Protein deglycase DJ-1 GO:0006517|GO:0030091 A4V04_RS03185 4642b0bf8c8cd62d5db9b24391f4b905 195 SUPERFAMILY SSF52317 7 177 7.03E-44 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS03185 4642b0bf8c8cd62d5db9b24391f4b905 195 Gene3D G3DSA:3.40.50.880 6 177 1.2E-50 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS03185 4642b0bf8c8cd62d5db9b24391f4b905 195 Pfam PF01965 DJ-1/PfpI family 7 170 4.8E-39 T 26-04-2017 IPR002818 DJ-1/PfpI A4V04_RS02110 b6ea01b49309b2815f42a6f5631c9810 193 Pfam PF13707 RloB-like protein 19 188 1.7E-20 T 26-04-2017 IPR025591 RloB-like protein A4V04_RS10730 f775dc51b5c0f19d5cad2818d8c5331b 421 Pfam PF03606 C4-dicarboxylate anaerobic carrier 59 420 2.2E-20 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS10730 f775dc51b5c0f19d5cad2818d8c5331b 421 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 57 414 1.8E-60 T 26-04-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A4V04_RS06520 8ded998ad5383b2fa68c568b9a0558e3 190 Pfam PF05713 Bacterial mobilisation protein (MobC) 123 160 1.3E-7 T 26-04-2017 IPR008687 Bacterial mobilisation A4V04_RS08035 a3cccb819e035428a865fbcf3c8ef2ce 175 Pfam PF02417 Chromate transporter 8 171 6.9E-28 T 26-04-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 A4V04_RS01375 b8eef3d9234e33ef9d14f26872d1b6da 860 SUPERFAMILY SSF103515 569 860 3.92E-14 T 26-04-2017 IPR005546 Autotransporter beta-domain A4V04_RS12220 f642ab17d8840b26ea3660bdfb0c85ec 100 Pfam PF05957 Bacterial protein of unknown function (DUF883) 9 100 4.6E-27 T 26-04-2017 IPR010279 Protein of unknown function DUF883, ElaB A4V04_RS09895 b69fe31231ade6ddf6cfd624f4add742 211 Gene3D G3DSA:3.90.350.10 141 178 2.2E-4 T 26-04-2017 IPR014736 Transposase, Tn5-like, core A4V04_RS09895 b69fe31231ade6ddf6cfd624f4add742 211 Pfam PF01609 Transposase DDE domain 7 198 2.2E-24 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS09895 b69fe31231ade6ddf6cfd624f4add742 211 SUPERFAMILY SSF53098 4 205 1.14E-22 T 26-04-2017 IPR012337 Ribonuclease H-like domain GO:0003676 A4V04_RS05220 3535927dc8006e27b6b7cb58e6fa7ab7 335 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 320 21.601 T 26-04-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A4V04_RS05220 3535927dc8006e27b6b7cb58e6fa7ab7 335 Pfam PF01867 CRISPR associated protein Cas1 4 263 3.7E-60 T 26-04-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A4V04_RS05220 3535927dc8006e27b6b7cb58e6fa7ab7 335 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 4 329 9.7E-57 T 26-04-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A4V04_RS03560 f539906521d86931065c35e8740e5baf 238 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 28 231 2.2E-42 T 26-04-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A4V04_RS03560 f539906521d86931065c35e8740e5baf 238 Gene3D G3DSA:3.90.850.10 22 232 6.6E-64 T 26-04-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A4V04_RS03560 f539906521d86931065c35e8740e5baf 238 SUPERFAMILY SSF56529 23 234 9.94E-56 T 26-04-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A4V04_RS09495 de9e8909edf99df3f5b14e04b31aaba4 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 280 1.4E-30 T 26-04-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A4V04_RS03785 f299414a66bd4ba9b050a41b5879c06d 256 Pfam PF05656 Protein of unknown function (DUF805) 12 133 2.3E-27 T 26-04-2017 IPR008523 Protein of unknown function DUF805 GO:0016021 A4V04_RS01400 10f0d9cea039da463bf75fadc85f01f6 178 Gene3D G3DSA:1.10.3290.10 5 177 4.0E-55 T 26-04-2017 IPR003812 Fido domain A4V04_RS01400 10f0d9cea039da463bf75fadc85f01f6 178 Pfam PF02661 Fic/DOC family 31 115 1.9E-10 T 26-04-2017 IPR003812 Fido domain A4V04_RS01400 10f0d9cea039da463bf75fadc85f01f6 178 SUPERFAMILY SSF140931 5 176 7.85E-37 T 26-04-2017 IPR003812 Fido domain A4V04_RS04285 cb27accaeb451b7e2a31a0f2cb549661 412 SUPERFAMILY SSF51905 1 55 5.18E-37 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04285 cb27accaeb451b7e2a31a0f2cb549661 412 SUPERFAMILY SSF51905 104 264 5.18E-37 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04285 cb27accaeb451b7e2a31a0f2cb549661 412 SUPERFAMILY SSF51905 352 408 5.18E-37 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04285 cb27accaeb451b7e2a31a0f2cb549661 412 Gene3D G3DSA:3.50.50.60 1 55 1.4E-31 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04285 cb27accaeb451b7e2a31a0f2cb549661 412 Gene3D G3DSA:3.50.50.60 106 107 1.4E-31 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04285 cb27accaeb451b7e2a31a0f2cb549661 412 Gene3D G3DSA:3.50.50.60 181 262 1.4E-31 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04285 cb27accaeb451b7e2a31a0f2cb549661 412 Gene3D G3DSA:3.50.50.60 352 411 1.4E-31 T 26-04-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4V04_RS04285 cb27accaeb451b7e2a31a0f2cb549661 412 Gene3D G3DSA:3.30.9.10 263 339 2.6E-4 T 26-04-2017 A4V04_RS04285 cb27accaeb451b7e2a31a0f2cb549661 412 Gene3D G3DSA:3.30.9.10 133 180 2.6E-4 T 26-04-2017 A4V04_RS04285 cb27accaeb451b7e2a31a0f2cb549661 412 Pfam PF01266 FAD dependent oxidoreductase 3 389 2.0E-38 T 26-04-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4V04_RS09635 eef199c6730e41f57b76c83eb766c603 126 Pfam PF03918 Cytochrome C biogenesis protein 17 125 5.7E-27 T 26-04-2017 IPR005616 CcmH/CycL/Ccl2/NrfF family A4V04_RS03635 715e2312d909eda0a65a29d134f2d23f 214 Pfam PF01609 Transposase DDE domain 4 94 3.5E-7 T 26-04-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4V04_RS03040 f2fc11c9d006a7685435aa77b5da21a2 106 SUPERFAMILY SSF143100 14 54 1.83E-5 T 26-04-2017 A4V04_RS03985 e164703137943cf74e0392f667baf280 152 Pfam PF06146 Phosphate-starvation-inducible E 51 118 6.3E-12 T 26-04-2017 IPR020948 Phosphate-starvation-induced PsiE-like A4V04_RS02570 9bd8fd8abbf1963a1bc7e1d7a1e65ff9 203 ProSitePatterns PS01007 Transposases, Mutator family, signature. 33 57 - T 26-04-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4V04_RS02570 9bd8fd8abbf1963a1bc7e1d7a1e65ff9 203 Pfam PF00872 Transposase, Mutator family 1 180 3.2E-54 T 26-04-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4V04_RS11515 c96a48eec1554462978806172b09ee83 185 SUPERFAMILY SSF88723 21 143 3.08E-5 T 26-04-2017 IPR029060 PIN domain-like A4V04_RS11515 c96a48eec1554462978806172b09ee83 185 Pfam PF14367 Domain of unknown function (DUF4411) 21 174 2.7E-31 T 26-04-2017 IPR016541 Uncharacterised conserved protein UCP008505 A4V04_RS03795 c19a8f0e4df244484c8eefeca6fb9ce2 304 Pfam PF05656 Protein of unknown function (DUF805) 12 134 2.2E-29 T 26-04-2017 IPR008523 Protein of unknown function DUF805 GO:0016021 A4V04_RS03435 1b635804b6a4070844646007c521b1a9 76 Gene3D G3DSA:1.10.3290.10 5 66 5.7E-5 T 26-04-2017 IPR003812 Fido domain A4V04_RS10710 0c12da14a9e5066f06eabb74b02f81a5 419 Pfam PF01136 Peptidase family U32 79 311 1.4E-69 T 26-04-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A4V04_RS10710 0c12da14a9e5066f06eabb74b02f81a5 419 ProSitePatterns PS01276 Peptidase family U32 signature. 172 190 - T 26-04-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A4V04_RS00650 c8274e444e4d89e67295ef693311000c 77 SUPERFAMILY SSF46955 5 48 9.7E-6 T 26-04-2017 IPR009061 Putative DNA-binding domain A4V04_RS07845 ec870185f0f22a7ae5271288c2e23ef4 92 Pfam PF03927 NapD protein 2 77 1.2E-19 T 26-04-2017 IPR005623 Chaperone NapD, nitrate reductase assembly A4V04_RS07985 1bdd3f763bcbf879ca01718abca3d066 295 Pfam PF03916 Polysulphide reductase, NrfD 12 289 5.5E-20 T 26-04-2017 IPR005614 NrfD family A4V04_RS01930 e35819574034d80d7003dbde74ecd504 376 Gene3D G3DSA:3.40.50.2000 211 372 1.9E-59 T 26-04-2017 A4V04_RS01930 e35819574034d80d7003dbde74ecd504 376 Gene3D G3DSA:3.40.50.2000 3 210 1.3E-76 T 26-04-2017 A4V04_RS01930 e35819574034d80d7003dbde74ecd504 376 SUPERFAMILY SSF53756 4 373 2.98E-121 T 26-04-2017 A4V04_RS01930 e35819574034d80d7003dbde74ecd504 376 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 372 3.7E-135 T 26-04-2017 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 A4V04_RS01930 e35819574034d80d7003dbde74ecd504 376 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 24 371 4.8E-112 T 26-04-2017 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4V04_RS01010 bdc778ab417d2d1c6f5f37d0f3cdf8fe 327 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 42 163 5.7E-34 T 26-04-2017 IPR007621 TPM domain A4V04_RS08335 d75c71ad6188fe06bbfa72b5bf0adee8 328 Pfam PF04015 Domain of unknown function (DUF362) 68 284 3.1E-35 T 26-04-2017 IPR007160 Domain of unknown function DUF362 A4V04_RS00720 1ea32ae6f519f7750b7b6fb1db74cb82 502 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 440 7.4E-151 T 26-04-2017 IPR002823 Protein of unknown function DUF112, transmembrane A4V04_RS04135 ec69de0567aa55bc40101626392fbd46 685 Pfam PF03050 Transposase IS66 family 270 594 3.6E-29 T 26-04-2017 IPR004291 Transposase, IS66 A4V04_RS01135 710eca0acd3d88900bd3a9f2ffcefebe 264 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 256 5.0E-79 T 26-04-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A4V04_RS01135 710eca0acd3d88900bd3a9f2ffcefebe 264 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 262 9.5E-84 T 26-04-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A4V04_RS01135 710eca0acd3d88900bd3a9f2ffcefebe 264 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 261 19.883 T 26-04-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A4V04_RS01135 710eca0acd3d88900bd3a9f2ffcefebe 264 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 138 150 - T 26-04-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A4V04_RS04015 390c15936f714c8e1843f6b9518281ba 262 SUPERFAMILY SSF52317 42 257 1.59E-64 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS04015 390c15936f714c8e1843f6b9518281ba 262 Pfam PF01965 DJ-1/PfpI family 67 249 5.5E-11 T 26-04-2017 IPR002818 DJ-1/PfpI A4V04_RS04015 390c15936f714c8e1843f6b9518281ba 262 Gene3D G3DSA:3.40.50.880 32 258 2.8E-76 T 26-04-2017 IPR029062 Class I glutamine amidotransferase-like A4V04_RS01420 55c3627865c3cef2e77e0efb9d4eff08 86 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 4 50 1.4E-14 T 26-04-2017 IPR010260 Prophage CP4-57 regulatory protein (AlpA) A4V04_RS03775 2f3412ea886e964568a42b6430130e78 483 Pfam PF13727 CoA-binding domain 84 247 9.2E-10 T 26-04-2017 A4V04_RS03775 2f3412ea886e964568a42b6430130e78 483 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 31 483 6.5E-116 T 26-04-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase A4V04_RS03775 2f3412ea886e964568a42b6430130e78 483 Pfam PF02397 Bacterial sugar transferase 285 476 1.7E-56 T 26-04-2017 IPR003362 Bacterial sugar transferase A4V04_RS03775 2f3412ea886e964568a42b6430130e78 483 TIGRFAM TIGR03022 WbaP_sugtrans: undecaprenyl-phosphate galactose phosphotransferase WbaP 22 483 6.8E-134 T 26-04-2017 IPR017472 Undecaprenyl-phosphate galactose phosphotransferase, WbaP GO:0000271|GO:0005886|GO:0016021|GO:0016740 A4V04_RS08155 c884e96174551bf1e002fc56d422f44a 188 Pfam PF02592 Putative vitamin uptake transporter 80 173 5.7E-10 T 26-04-2017 IPR003744 Protein of unknown function DUF165 A4V04_RS02200 a21918de312275f8302aa79894453a07 192 SUPERFAMILY SSF103481 111 187 4.58E-8 T 26-04-2017 A4V04_RS06405 65eca0c8f1d34988b6cc5f747d568e3c 316 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 22 3.3E-7 T 26-04-2017 IPR024973 ESPR domain A4V04_RS02650 ef1d62aedaf121b3f5aad0dcf30fb085 123 Pfam PF08388 Group II intron, maturase-specific domain 8 71 1.1E-13 T 26-04-2017 IPR013597 Group II intron, maturase-specific A4V04_RS04055 54a87273da42e239eca35a3f1b954367 599 Pfam PF02690 Na+/Pi-cotransporter 215 297 3.7E-9 T 26-04-2017 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 A4V04_RS04055 54a87273da42e239eca35a3f1b954367 599 Pfam PF02690 Na+/Pi-cotransporter 49 188 9.1E-29 T 26-04-2017 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 A4V04_RS08185 abae412ec9d58dde17f6b37586f72b9a 477 TIGRFAM TIGR00797 matE: MATE efflux family protein 36 446 5.8E-72 T 26-04-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4V04_RS08185 abae412ec9d58dde17f6b37586f72b9a 477 PIRSF PIRSF006603 19 477 5.0E-83 T 26-04-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4V04_RS08185 abae412ec9d58dde17f6b37586f72b9a 477 Pfam PF01554 MatE 274 435 3.4E-28 T 26-04-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4V04_RS08185 abae412ec9d58dde17f6b37586f72b9a 477 Pfam PF01554 MatE 36 194 8.9E-31 T 26-04-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4V04_RS12340 f71c31b56da6789911682e185ae53bc8 181 SUPERFAMILY SSF52218 1 167 1.12E-28 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS12340 f71c31b56da6789911682e185ae53bc8 181 Gene3D G3DSA:3.40.50.360 1 179 2.6E-27 T 26-04-2017 IPR029039 Flavoprotein-like domain A4V04_RS12340 f71c31b56da6789911682e185ae53bc8 181 Pfam PF12724 Flavodoxin domain 5 155 1.0E-35 T 26-04-2017 IPR026816 Flavodoxin domain A4V04_RS12815 2fde86716aa0bd403d9af7f188b8c4c5 530 Pfam PF09820 Predicted AAA-ATPase 10 286 1.3E-72 T 26-04-2017 IPR018631 AAA-ATPase-like domain A4V04_RS12815 2fde86716aa0bd403d9af7f188b8c4c5 530 Pfam PF08011 PD-(D/E)XK nuclease superfamily 431 527 1.8E-14 T 26-04-2017 IPR012547 PD-(D/E)XK nuclease superfamily 9 A4V04_RS08815 92d8f9ef12bfce56a3e58174f46268a0 424 Pfam PF03606 C4-dicarboxylate anaerobic carrier 68 423 4.9E-23 T 26-04-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A4V04_RS08815 92d8f9ef12bfce56a3e58174f46268a0 424 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 63 417 1.1E-58 T 26-04-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 A4V04_RS01905 9d6048f4a400041eea47c50e04ad36ec 129 Pfam PF04138 GtrA-like protein 12 127 8.9E-19 T 26-04-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 A4V04_RS11875 c0dcc38276bda86c339fff135409d9b3 222 Pfam PF01618 MotA/TolQ/ExbB proton channel family 81 181 3.0E-26 T 26-04-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 A4V04_RS04010 28629d0b5645eb7a6fc38eb2b721c985 34 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 2 31 1.2E-11 T 26-04-2017 IPR009614 Toxin YoeB GO:0004519|GO:0006401 A4V04_RS04010 28629d0b5645eb7a6fc38eb2b721c985 34 SUPERFAMILY SSF143011 2 30 2.09E-8 T 26-04-2017 A4V04_RS10290 27db5f5da7bb36089baaf98ed4edc966 100 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 1 80 3.6E-17 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS10290 27db5f5da7bb36089baaf98ed4edc966 100 Pfam PF04221 RelB antitoxin 5 55 3.3E-13 T 26-04-2017 IPR007337 RelB antitoxin/Antitoxin DinJ A4V04_RS10760 f117c51da9ed2f0b4513b1076c0a1e76 488 Pfam PF00474 Sodium:solute symporter family 31 427 1.0E-40 T 26-04-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A4V04_RS05125 e2489177dab401446b62cc14eb41155b 108 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 8 103 4.6E-14 T 26-04-2017 IPR008407 Branched-chain amino acid transport, AzlD A4V04_RS06745 d9249c0c5a416431315317d1da111a52 168 Pfam PF03918 Cytochrome C biogenesis protein 26 156 1.3E-50 T 26-04-2017 IPR005616 CcmH/CycL/Ccl2/NrfF family A4V04_RS11815 401d0a48c372047be0aaa925ce5e8d03 125 PIRSF PIRSF021239 11 124 4.2E-50 T 26-04-2017 IPR007437 Putative member of DMT superfamily A4V04_RS11815 401d0a48c372047be0aaa925ce5e8d03 125 Pfam PF04342 Putative member of DMT superfamily (DUF486) 17 121 1.3E-42 T 26-04-2017 IPR007437 Putative member of DMT superfamily A4V04_RS06340 8abca4e1b815cf6b4b447c426806d6d7 106 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 5 71 4.7E-12 T 26-04-2017 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB A4V04_RS03215 a76db258332d6e95ad642a89ec729849 256 Pfam PF01925 Sulfite exporter TauE/SafE 12 246 4.8E-38 T 26-04-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 A4V04_RS00500 cf7f91d031bda99d18e411c36e06f45d 498 Pfam PF11863 Protein of unknown function (DUF3383) 8 492 1.4E-99 T 26-04-2017 IPR021808 Protein of unknown function DUF3383 A4V04_RS08645 c2b65548ead675f7f6b7864c895af731 332 Pfam PF01863 Protein of unknown function DUF45 110 323 5.5E-38 T 26-04-2017 IPR002725 Protein of unknown function DUF45 A4V04_RS00565 202a02d95b1dd15baa5137f57a23a760 330 Pfam PF10065 Uncharacterized conserved protein (DUF2303) 57 327 3.0E-49 T 26-04-2017 IPR019276 Protein of unkown function DUF2303 A4V04_RS01325 a5c07ec8c44e2f0514bc1bae03157443 80 Pfam PF14294 Domain of unknown function (DUF4372) 18 51 5.8E-8 T 26-04-2017 IPR025399 Domain of unknown function DUF4372 A4V04_RS08030 625e123a530f03220b88bc04e308c298 198 Pfam PF02417 Chromate transporter 15 176 1.1E-25 T 26-04-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 A4V04_RS06225 92f87f92b7000d8338f87c3a0f49874e 140 SUPERFAMILY SSF50249 34 128 2.33E-5 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS06225 92f87f92b7000d8338f87c3a0f49874e 140 Gene3D G3DSA:2.40.50.140 35 135 7.6E-7 T 26-04-2017 IPR012340 Nucleic acid-binding, OB-fold A4V04_RS01300 1f7e6d7f76b77fed216ec95efa706258 508 Pfam PF00939 Sodium:sulfate symporter transmembrane region 47 499 8.1E-88 T 26-04-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A4V04_RS01300 1f7e6d7f76b77fed216ec95efa706258 508 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 48 499 4.1E-97 T 26-04-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A4V04_RS11485 14c36c385e6109ebe7e8692242654573 205 Pfam PF01810 LysE type translocator 15 204 4.8E-34 T 26-04-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 A4V04_RS05225 604bca53e5cbe7215645c6a9c100a655 1422 TIGRFAM TIGR03031 cas_csx12: CRISPR system subtype II-B RNA-guided endonuclease Cas9/Csx12 9 800 6.3E-128 T 26-04-2017 IPR013492 CRISPR system subtype II-B RNA-guided endonuclease Cas9/Csx12 A4V04_RS09890 5c6fa1e0aa8d68c75766dc4ad2d3f09c 50 Pfam PF14294 Domain of unknown function (DUF4372) 2 45 6.6E-11 T 26-04-2017 IPR025399 Domain of unknown function DUF4372 A4V04_RS00695 881421c94d53e8ef675998e7c67bad4b 1224 Gene3D G3DSA:3.40.50.300 6 150 1.4E-5 T 26-04-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4V04_RS04615 6804a79c6b30478a5f557c65a3350826 149 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 9 143 8.7E-14 T 26-04-2017 IPR009936 Protein of unknown function DUF1468 A4V04_RS05570 3fff385ab832974f30236a0ee5968546 355 SUPERFAMILY SSF56235 25 176 3.34E-90 T 26-04-2017 IPR029055 Nucleophile aminohydrolases, N-terminal A4V04_RS05570 3fff385ab832974f30236a0ee5968546 355 SUPERFAMILY SSF56235 210 342 3.34E-90 T 26-04-2017 IPR029055 Nucleophile aminohydrolases, N-terminal A4V04_RS05570 3fff385ab832974f30236a0ee5968546 355 Pfam PF01112 Asparaginase 27 342 7.2E-109 T 26-04-2017 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 A4V04_RS02050 45b00b03d28e1e9eba179c801bbd3eb9 130 Pfam PF05717 IS66 Orf2 like protein 9 107 4.3E-16 T 26-04-2017 IPR008878 Transposase IS66, Orf2 A4V04_RS02825 081fa0289224e0f5ae3dffd4d1bfd1c0 173 Pfam PF02620 Uncharacterized ACR, COG1399 65 170 5.3E-19 T 26-04-2017 IPR003772 Protein of unknown function DUF177 A4V04_RS11775 11e4e9193373411a44a389d401339005 118 Pfam PF05717 IS66 Orf2 like protein 10 109 2.7E-16 T 26-04-2017 IPR008878 Transposase IS66, Orf2 A4V04_RS02525 a507e1efa5c700493b2650334f433804 79 SUPERFAMILY SSF55031 32 72 7.12E-5 T 26-04-2017 IPR011650 Peptidase M20, dimerisation domain A4V04_RS01310 187dcf18b618bcd9f8e96243c09ddfb3 502 Pfam PF00474 Sodium:solute symporter family 33 428 4.2E-48 T 26-04-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A4V04_RS13085 48bc9877e8583df3036a7c579b068b3e 224 Gene3D G3DSA:1.10.3720.10 10 221 5.9E-35 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS13085 48bc9877e8583df3036a7c579b068b3e 224 SUPERFAMILY SSF161098 9 217 2.49E-41 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS13085 48bc9877e8583df3036a7c579b068b3e 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 216 3.9E-12 T 26-04-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4V04_RS12160 4e9c7c54f5409a6bfd7700276b1057f3 255 Pfam PF10670 Domain of unknown function (DUF4198) 17 223 1.1E-49 T 26-04-2017 IPR019613 Protein of unknown function DUF4198 A4V04_RS09970 1774dbf7c73d4fbb42fc1c2b5107a391 192 Pfam PF14334 Domain of unknown function (DUF4390) 41 185 1.8E-42 T 26-04-2017 IPR025500 Protein of unknown function DUF4390 A4V04_RS04835 fc566a6906476713bef5602ee86a022d 194 Pfam PF01810 LysE type translocator 16 192 3.6E-13 T 26-04-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 A4V04_RS02960 22ce92ef77b1c8f525f80200dc497497 300 Pfam PF02535 ZIP Zinc transporter 146 295 7.9E-28 T 26-04-2017 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 A4V04_RS12885 b158c79eee0515401c856841ea8cf7c8 54 Pfam PF02371 Transposase IS116/IS110/IS902 family 2 53 1.5E-10 T 26-04-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4V04_RS09260 b7c030b0ee7d5b22ccc387e275ef8424 63 Pfam PF11146 Protein of unknown function (DUF2905) 2 62 4.2E-16 T 26-04-2017 IPR021320 Protein of unknown function DUF2905 A4V04_RS03415 ce5e78d378c7a08ca66bda66158b78bd 233 Pfam PF10670 Domain of unknown function (DUF4198) 71 205 5.5E-17 T 26-04-2017 IPR019613 Protein of unknown function DUF4198 A4V04_RS09310 3d6b7b7e75b46a38b2ae19435079735f 233 Pfam PF04340 Protein of unknown function, DUF484 14 209 8.5E-6 T 26-04-2017 IPR007435 Protein of unknown function DUF484 A4V04_RS04915 a119086492da274805adab6fed3cb1f8 392 Gene3D G3DSA:1.10.3290.10 161 283 8.1E-6 T 26-04-2017 IPR003812 Fido domain A4V04_RS06880 ac0b38b6399ab1f87e65209aa812aef2 150 Pfam PF05656 Protein of unknown function (DUF805) 17 110 1.2E-22 T 26-04-2017 IPR008523 Protein of unknown function DUF805 GO:0016021 A4V04_RS01710 612ce2817f0121c8b0d7e72d808a3102 438 SUPERFAMILY SSF53756 101 352 4.27E-10 T 26-04-2017 A4V04_RS02455 e5eddcdb21c44068b8b612f7a05f55f6 509 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 19 438 3.8E-144 T 26-04-2017 IPR002823 Protein of unknown function DUF112, transmembrane A4V04_RS04490 e9ec6a689b664fcc3c832c74ad149388 219 Pfam PF03458 UPF0126 domain 12 82 5.2E-19 T 26-04-2017 IPR005115 Uncharacterised domain UPF0126 A4V04_RS04490 e9ec6a689b664fcc3c832c74ad149388 219 Pfam PF03458 UPF0126 domain 101 174 8.6E-18 T 26-04-2017 IPR005115 Uncharacterised domain UPF0126 A4V04_RS10890 11d6556c8211b3d1a381b01098885447 88 Pfam PF09600 Cyd operon protein YbgE (Cyd_oper_YbgE) 1 74 1.5E-24 T 26-04-2017 IPR011846 Cyd operon protein YbgE A4V04_RS06480 93fcbee570819582f920838d87f1b315 529 Pfam PF07120 Protein of unknown function (DUF1376) 10 92 3.8E-9 T 26-04-2017 IPR010781 Protein of unknown function DUF1376 A4V04_RS09725 1a509bb089eb6ce8cd440355fe57958f 143 Pfam PF01957 NfeD-like C-terminal, partner-binding 6 138 2.0E-10 T 26-04-2017 IPR002810 NfeD-like, C-terminal domain A4V04_RS02235 d76474bd95fa65476eeaa98dee498c26 292 SUPERFAMILY SSF103481 50 144 6.28E-5 T 26-04-2017 A4V04_RS10305 11f11982eaefadf75506bb3c0f074be9 64 Gene3D G3DSA:1.20.950.20 6 61 4.0E-7 T 26-04-2017 A4V04_RS04620 9aad6d11fb9fb64c557eca5a841ecf81 502 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 440 5.2E-142 T 26-04-2017 IPR002823 Protein of unknown function DUF112, transmembrane A4V04_RS05100 6d97203d762869ab9fcb1be5228380de 156 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 21 152 3.8E-23 T 26-04-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component A4V04_RS02680 183a8a1247f100efdfa1dcf4737cb072 284 Pfam PF03724 META domain 47 136 4.3E-12 T 26-04-2017 IPR005184 Domain of unknown function DUF306, Meta/HslJ A4V04_RS10720 de04b9360b7b324bc0c7046aabac2396 210 Pfam PF01810 LysE type translocator 14 206 1.1E-42 T 26-04-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 A4V04_RS12685 c4faf826104617166fc94d2605c44088 673 Pfam PF03050 Transposase IS66 family 271 585 2.4E-29 T 26-04-2017 IPR004291 Transposase, IS66 A4V04_RS10620 3854a230f874fe8cdaf85d14460395c1 333 Pfam PF02470 MlaD protein 48 136 3.2E-11 T 26-04-2017 IPR003399 Mce/MlaD A4V04_RS06460 645f3620b766bd4585eeb9dc94c12277 101 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 10 59 1.0E-8 T 26-04-2017 IPR010260 Prophage CP4-57 regulatory protein (AlpA) A4V04_RS00405 430bf63485b24be94f9c000a82fa13b0 127 Pfam PF16083 LydA holin phage, holin superfamily III 25 94 5.3E-11 T 26-04-2017 IPR032126 LydA-like holin