locus-tag	class	description
JYK05_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JYK05_RS00025	COG0513	Belongs to the DEAD box helicase family
JYK05_RS00030	COG2814	Major facilitator Superfamily
JYK05_RS00070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYK05_RS00075	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JYK05_RS00080	COG0583	DNA-binding transcription factor activity
JYK05_RS00095	COG0758	DNA mediated transformation
JYK05_RS00100	COG0242	peptide deformylase activity
JYK05_RS00115	COG0501	Belongs to the peptidase M48B family
JYK05_RS00120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JYK05_RS00120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JYK05_RS00130	COG5000	phosphorelay sensor kinase activity
JYK05_RS00135	COG2204	response regulator
JYK05_RS00145	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JYK05_RS00150	COG0602	queuosine metabolic process
JYK05_RS00155	COG0720	synthase
JYK05_RS00170	COG0772	Belongs to the SEDS family
JYK05_RS00175	COG0768	penicillin binding
JYK05_RS00185	COG1792	Involved in formation and maintenance of cell shape
JYK05_RS00190	COG1077	Cell shape determining protein MreB Mrl
JYK05_RS00195	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JYK05_RS00200	COG0154	amidase activity
JYK05_RS00205	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JYK05_RS00210	COG2326	polyphosphate kinase activity
JYK05_RS00215	COG0708	Exodeoxyribonuclease III
JYK05_RS00225	COG2814	Major facilitator Superfamily
JYK05_RS00255	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JYK05_RS00270	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JYK05_RS00275	COG0840	transmembrane signaling receptor activity
JYK05_RS00280	COG2233	PERMEase
JYK05_RS00285	COG0025	NhaP-type Na H and K H
JYK05_RS00290	COG2199	diguanylate cyclase activity
JYK05_RS00290	COG2200	EAL domain
JYK05_RS00300	COG0625	glutathione transferase activity
JYK05_RS00325	COG1609	Transcriptional regulator
JYK05_RS00345	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JYK05_RS00355	COG0596	Alpha beta hydrolase
JYK05_RS00360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JYK05_RS00380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JYK05_RS00400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JYK05_RS00405	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JYK05_RS00410	COG0156	8-amino-7-oxononanoate synthase activity
JYK05_RS00430	COG3012	SEC-C Motif Domain Protein
JYK05_RS00440	COG0300	oxidoreductase activity
JYK05_RS00445	COG0183	Belongs to the thiolase family
JYK05_RS00455	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
JYK05_RS00460	COG0789	Transcriptional regulator
JYK05_RS00470	COG0747	negative chemotaxis
JYK05_RS00490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JYK05_RS00500	COG0667	Aldo Keto reductase
JYK05_RS00505	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JYK05_RS00520	COG2818	Glycosylase
JYK05_RS00545	COG0438	transferase activity, transferring glycosyl groups
JYK05_RS00560	COG1360	Flagellar Motor Protein
JYK05_RS00570	COG0643	Histidine kinase
JYK05_RS00570	COG2198	Histidine kinase
JYK05_RS00580	COG0840	transmembrane signaling receptor activity
JYK05_RS00590	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JYK05_RS00595	COG2201	protein-glutamate methylesterase activity
JYK05_RS00600	COG0745	RESPONSE REGULATOR receiver
JYK05_RS00605	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
JYK05_RS00625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JYK05_RS00635	COG0018	arginyl-trna synthetase
JYK05_RS00665	COG0596	Alpha beta hydrolase
JYK05_RS00690	COG1024	Enoyl-CoA hydratase
JYK05_RS00710	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JYK05_RS00730	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JYK05_RS00735	COG1127	ABC transporter
JYK05_RS00765	COG1686	Belongs to the peptidase S11 family
JYK05_RS00775	COG2921	Belongs to the UPF0250 family
JYK05_RS00780	COG0583	DNA-binding transcription factor activity
JYK05_RS00790	COG0321	lipoyl(octanoyl) transferase activity
JYK05_RS00800	COG1301	dicarboxylic acid transport
JYK05_RS00805	COG4191	Histidine kinase
JYK05_RS00825	COG0606	chelatase, subunit chli
JYK05_RS00830	COG2960	long-chain fatty acid transporting porin activity
JYK05_RS00840	COG0004	ammonium transporteR
JYK05_RS00850	COG0189	ligase activity
JYK05_RS00860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JYK05_RS00865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JYK05_RS00870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JYK05_RS00875	COG0793	Belongs to the peptidase S41A family
JYK05_RS00885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JYK05_RS00890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JYK05_RS00895	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
JYK05_RS00900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JYK05_RS00905	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JYK05_RS00910	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JYK05_RS00915	COG1040	competence protein
JYK05_RS00920	COG2226	methyltransferase
JYK05_RS00935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JYK05_RS00945	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JYK05_RS00975	COG1612	heme a metabolic process
JYK05_RS00980	COG0109	protoheme IX farnesyltransferase activity
JYK05_RS00985	COG1999	signal sequence binding
JYK05_RS01000	COG1846	Transcriptional regulator
JYK05_RS01000	COG0456	acetyltransferase
JYK05_RS01005	COG2188	Transcriptional regulator
JYK05_RS01010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JYK05_RS01015	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JYK05_RS01020	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JYK05_RS01020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JYK05_RS01025	COG1263	PTS System
JYK05_RS01025	COG2190	(PTS) system
JYK05_RS01025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JYK05_RS01030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JYK05_RS01045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JYK05_RS01050	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JYK05_RS01060	COG0625	glutathione transferase activity
JYK05_RS01075	COG0742	ribosomal rna small subunit methyltransferase
JYK05_RS01080	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JYK05_RS01100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JYK05_RS01105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JYK05_RS01115	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JYK05_RS01120	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JYK05_RS01135	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JYK05_RS01145	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JYK05_RS01150	COG1194	a g-specific adenine glycosylase
JYK05_RS01160	COG1660	Displays ATPase and GTPase activities
JYK05_RS01165	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JYK05_RS01175	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JYK05_RS01180	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JYK05_RS01185	COG1137	ATPase activity
JYK05_RS01200	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JYK05_RS01215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JYK05_RS01245	COG2814	Major facilitator Superfamily
JYK05_RS01250	COG0629	single-stranded DNA binding
JYK05_RS01255	COG2197	response regulator
JYK05_RS01260	COG2197	response regulator
JYK05_RS01265	COG2197	response regulator
JYK05_RS01270	COG2205	protein histidine kinase activity
JYK05_RS01270	COG0784	Response regulator, receiver
JYK05_RS01275	COG0583	DNA-binding transcription factor activity
JYK05_RS01300	COG0477	Major facilitator Superfamily
JYK05_RS01315	COG1737	Transcriptional regulator
JYK05_RS01320	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JYK05_RS01335	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JYK05_RS01335	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JYK05_RS01345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JYK05_RS01355	COG0247	lactate metabolic process
JYK05_RS01370	COG2226	methyltransferase
JYK05_RS01385	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JYK05_RS01405	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JYK05_RS01410	COG0494	nUDIX hydrolase
JYK05_RS01425	COG1960	acyl-CoA dehydrogenase activity
JYK05_RS01430	COG1024	Enoyl-CoA hydratase
JYK05_RS01430	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYK05_RS01435	COG0183	Belongs to the thiolase family
JYK05_RS01440	COG1024	Enoyl-CoA hydratase
JYK05_RS01445	COG3755	Protein conserved in bacteria
JYK05_RS01450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JYK05_RS01465	COG1607	acyl-coa hydrolase
JYK05_RS01470	COG5265	(ABC) transporter
JYK05_RS01480	COG2223	nitrite transmembrane transporter activity
JYK05_RS01485	COG0583	DNA-binding transcription factor activity
JYK05_RS01490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JYK05_RS01500	COG0765	amino acid transport
JYK05_RS01505	COG0765	amino acid transport
JYK05_RS01510	COG1126	abc transporter atp-binding protein
JYK05_RS01515	COG0121	glutamine amidotransferase
JYK05_RS01520	COG0418	dihydroorotase activity
JYK05_RS01545	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JYK05_RS01550	COG0316	Belongs to the HesB IscA family
JYK05_RS01555	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JYK05_RS01560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JYK05_RS01565	COG1490	D-aminoacyl-tRNA deacylase activity
JYK05_RS01580	COG2255	four-way junction helicase activity
JYK05_RS01585	COG0632	four-way junction helicase activity
JYK05_RS01590	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JYK05_RS01595	COG0138	bifunctional purine biosynthesis protein purh
JYK05_RS01600	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JYK05_RS01610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JYK05_RS01615	COG0006	proline dipeptidase activity
JYK05_RS01650	COG0482	sulfurtransferase activity
JYK05_RS01665	COG0625	glutathione transferase activity
JYK05_RS01675	COG3008	intermembrane lipid transfer
JYK05_RS01680	COG2995	paraquat-inducible protein a
JYK05_RS01690	COG3038	cytochrome b561
JYK05_RS01695	COG2353	YceI-like domain
JYK05_RS01700	COG2353	YceI-like domain
JYK05_RS01705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JYK05_RS01710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JYK05_RS01715	COG1862	Preprotein translocase
JYK05_RS01720	COG0343	queuine tRNA-ribosyltransferase activity
JYK05_RS01725	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JYK05_RS01730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JYK05_RS01740	COG3152	Membrane
JYK05_RS01745	COG0753	catalase activity
JYK05_RS01755	COG0783	Belongs to the Dps family
JYK05_RS01780	COG0247	lactate metabolic process
JYK05_RS01785	COG0277	FAD linked oxidase domain protein
JYK05_RS01790	COG0277	FAD linked oxidase domain protein
JYK05_RS01795	COG0277	FAD linked oxidase domain protein
JYK05_RS01800	COG2096	Adenosyltransferase
JYK05_RS01805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JYK05_RS01810	COG0312	modulator of DNA gyrase
JYK05_RS01815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JYK05_RS01825	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JYK05_RS01830	COG0497	DNA recombination
JYK05_RS01840	COG1420	regulation of RNA biosynthetic process
JYK05_RS01845	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JYK05_RS01860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JYK05_RS01870	COG0443	Heat shock 70 kDa protein
JYK05_RS01880	COG0512	Glutamine amidotransferase of anthranilate synthase
JYK05_RS01880	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JYK05_RS01885	COG4948	Mandelate Racemase Muconate Lactonizing
JYK05_RS01890	COG2186	Transcriptional regulator
JYK05_RS01895	COG0346	lactoylglutathione lyase activity
JYK05_RS01905	COG0204	Acyl-transferase
JYK05_RS01910	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JYK05_RS01915	COG0751	glycine-tRNA ligase activity
JYK05_RS01920	COG0752	glycyl-tRNA synthetase alpha subunit
JYK05_RS01935	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JYK05_RS01940	COG4535	Mg2 and Co2 transporter CorC
JYK05_RS01945	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
JYK05_RS01950	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JYK05_RS01955	COG1702	phosphate starvation-inducible protein PhoH
JYK05_RS01960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JYK05_RS01965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JYK05_RS02000	COG0513	Belongs to the DEAD box helicase family
JYK05_RS02005	COG1272	protein, Hemolysin III
JYK05_RS02030	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JYK05_RS02035	COG1428	Deoxynucleoside kinase
JYK05_RS02040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JYK05_RS02045	COG0617	tRNA 3'-terminal CCA addition
JYK05_RS02055	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JYK05_RS02060	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JYK05_RS02065	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JYK05_RS02070	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JYK05_RS02075	COG0586	Pfam SNARE associated Golgi protein
JYK05_RS02085	COG1388	LysM domain
JYK05_RS02085	COG4942	peptidase
JYK05_RS02115	COG0642	Histidine kinase
JYK05_RS02125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JYK05_RS02130	COG2137	regulation of response to DNA damage stimulus
JYK05_RS02140	COG0045	succinate-CoA ligase (ADP-forming) activity
JYK05_RS02145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JYK05_RS02150	COG0861	Integral membrane protein TerC family
JYK05_RS02155	COG4969	Belongs to the N-Me-Phe pilin family
JYK05_RS02165	COG0315	cyclic pyranopterin monophosphate synthase activity
JYK05_RS02170	COG4783	chaperone-mediated protein folding
JYK05_RS02180	COG0429	hydrolase of the alpha beta-hydrolase fold
JYK05_RS02190	COG0859	PFAM glycosyl transferase family 9
JYK05_RS02215	COG0126	phosphoglycerate kinase activity
JYK05_RS02220	COG0469	pyruvate kinase activity
JYK05_RS02230	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JYK05_RS02235	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JYK05_RS02240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JYK05_RS02245	COG0009	L-threonylcarbamoyladenylate synthase
JYK05_RS02265	COG2027	D-alanyl-D-alanine carboxypeptidase
JYK05_RS02290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JYK05_RS02315	COG1309	transcriptional regulator
JYK05_RS02320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JYK05_RS02325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JYK05_RS02365	COG2233	PERMEase
JYK05_RS02390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JYK05_RS02395	COG1121	(ABC) transporter
JYK05_RS02400	COG0803	Belongs to the bacterial solute-binding protein 9 family
JYK05_RS02405	COG0735	belongs to the Fur family
JYK05_RS02420	COG1175	transmembrane transport
JYK05_RS02435	COG3842	ATPase activity
JYK05_RS02440	COG3217	Mosc domain protein beta barrel domain protein
JYK05_RS02440	COG0633	Ferredoxin
JYK05_RS02450	COG1070	Carbohydrate kinase
JYK05_RS02455	COG0246	Mannitol dehydrogenase
JYK05_RS02460	COG1070	Carbohydrate kinase
JYK05_RS02495	COG2814	Major facilitator Superfamily
JYK05_RS02520	COG1201	RNA secondary structure unwinding
JYK05_RS02525	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JYK05_RS02525	COG1793	dna ligase
JYK05_RS02530	COG1793	dna ligase
JYK05_RS02530	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JYK05_RS02540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYK05_RS02545	COG0583	DNA-binding transcription factor activity
JYK05_RS02550	COG2985	domain, Protein
JYK05_RS02555	COG2985	domain, Protein
JYK05_RS02575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JYK05_RS02580	COG0601	transmembrane transport
JYK05_RS02585	COG4166	transmembrane transport
JYK05_RS02620	COG1278	Cold shock
JYK05_RS02625	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JYK05_RS02630	COG0542	response to heat
JYK05_RS02635	COG0756	dUTP diphosphatase activity
JYK05_RS02640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JYK05_RS02645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JYK05_RS02650	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JYK05_RS02655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JYK05_RS02660	COG0196	riboflavin kinase activity
JYK05_RS02665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JYK05_RS02670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JYK05_RS02670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JYK05_RS02675	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JYK05_RS02675	COG3264	Mechanosensitive ion channel
JYK05_RS02685	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JYK05_RS02695	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JYK05_RS02700	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JYK05_RS02715	COG1047	Peptidyl-prolyl cis-trans
JYK05_RS02720	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JYK05_RS02750	COG0456	acetyltransferase
JYK05_RS02755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JYK05_RS02805	COG0583	DNA-binding transcription factor activity
JYK05_RS02810	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JYK05_RS02820	COG0175	sulfate reduction
JYK05_RS02830	COG2895	sulfate adenylyltransferase (ATP) activity
JYK05_RS02835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JYK05_RS02835	COG1648	precorrin-2 dehydrogenase activity
JYK05_RS02865	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JYK05_RS02885	COG0583	DNA-binding transcription factor activity
JYK05_RS02890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JYK05_RS02910	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JYK05_RS02920	COG4206	TonB-dependent receptor
JYK05_RS02925	COG4139	cobalamin transport
JYK05_RS02930	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JYK05_RS02935	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JYK05_RS02940	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JYK05_RS02950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JYK05_RS02970	COG1492	cobalamin metabolic process
JYK05_RS02980	COG0489	protein tyrosine kinase activity
JYK05_RS02990	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JYK05_RS02995	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JYK05_RS03025	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYK05_RS03025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYK05_RS03030	COG3047	cAMP biosynthetic process
JYK05_RS03030	COG2885	chlorophyll binding
JYK05_RS03035	COG0489	protein tyrosine kinase activity
JYK05_RS03045	COG0717	Belongs to the dCTP deaminase family
JYK05_RS03055	COG0625	glutathione transferase activity
JYK05_RS03060	COG3781	membrane
JYK05_RS03100	COG1450	Type ii and iii secretion system protein
JYK05_RS03130	COG1459	type II secretion system
JYK05_RS03135	COG2165	general secretion pathway protein
JYK05_RS03165	COG0181	hydroxymethylbilane synthase activity
JYK05_RS03185	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JYK05_RS03190	COG2860	membrane
JYK05_RS03195	COG2840	Smr protein MutS2
JYK05_RS03200	COG0492	ferredoxin-NADP+ reductase activity
JYK05_RS03205	COG1674	ftsk spoiiie
JYK05_RS03210	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JYK05_RS03230	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JYK05_RS03235	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JYK05_RS03250	COG0024	Methionine aminopeptidase
JYK05_RS03260	COG0850	regulation of cytokinetic process
JYK05_RS03270	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JYK05_RS03290	COG0477	Major facilitator Superfamily
JYK05_RS03320	COG2814	Major facilitator Superfamily
JYK05_RS03325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JYK05_RS03330	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JYK05_RS03335	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JYK05_RS03340	COG1561	YicC-like family, N-terminal region
JYK05_RS03345	COG0194	GDP metabolic process
JYK05_RS03355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JYK05_RS03380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JYK05_RS03390	COG1199	ATP-dependent helicase activity
JYK05_RS03390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JYK05_RS03410	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
JYK05_RS03450	COG0028	Belongs to the TPP enzyme family
JYK05_RS03450	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
JYK05_RS03455	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JYK05_RS03465	COG0402	S-adenosylhomocysteine deaminase activity
JYK05_RS03470	COG2252	PERMEase
JYK05_RS03475	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JYK05_RS03485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JYK05_RS03495	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JYK05_RS03505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JYK05_RS03535	COG0762	integral membrane protein
JYK05_RS03565	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JYK05_RS03575	COG0436	Aminotransferase
JYK05_RS03580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JYK05_RS03585	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JYK05_RS03610	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JYK05_RS03610	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JYK05_RS03615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JYK05_RS03625	COG2814	Major facilitator Superfamily
JYK05_RS03630	COG1505	serine-type exopeptidase activity
JYK05_RS03635	COG3842	ATPase activity
JYK05_RS03640	COG0395	ABC-type sugar transport system, permease component
JYK05_RS03645	COG1175	transmembrane transport
JYK05_RS03655	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JYK05_RS03660	COG0363	glucosamine-6-phosphate deaminase activity
JYK05_RS03665	COG1737	Transcriptional regulator
JYK05_RS03665	COG0837	glucose binding
JYK05_RS03695	COG1741	Belongs to the pirin family
JYK05_RS03735	COG1116	anion transmembrane transporter activity
JYK05_RS03765	COG2204	response regulator
JYK05_RS03795	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JYK05_RS03835	COG0693	protein deglycase activity
JYK05_RS03840	COG2814	Major facilitator Superfamily
JYK05_RS03845	COG1881	PFAM PEBP family protein
JYK05_RS03855	COG1309	transcriptional regulator
JYK05_RS03860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JYK05_RS03865	COG1082	Xylose isomerase domain protein TIM barrel
JYK05_RS03865	COG3185	4-Hydroxyphenylpyruvate dioxygenase
JYK05_RS03885	COG0702	epimerase
JYK05_RS03890	COG0583	DNA-binding transcription factor activity
JYK05_RS03900	COG0784	Response regulator, receiver
JYK05_RS03900	COG4191	Histidine kinase
JYK05_RS03915	COG2267	carboxylic ester hydrolase activity
JYK05_RS03930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JYK05_RS03935	COG1773	rubredoxin
JYK05_RS03945	COG0488	(ABC) transporter
JYK05_RS03970	COG0384	phenazine biosynthesis protein PhzF
JYK05_RS03980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JYK05_RS03985	COG0697	spore germination
JYK05_RS04015	COG3161	chorismate lyase activity
JYK05_RS04045	COG2764	glyoxalase bleomycin resistance protein dioxygenase
JYK05_RS04050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JYK05_RS04060	COG3135	benzoate transporter
JYK05_RS04075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JYK05_RS04095	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JYK05_RS04100	COG2878	Part of a membrane complex involved in electron transport
JYK05_RS04105	COG1309	transcriptional regulator
JYK05_RS04120	COG3387	PFAM Glycoside hydrolase 15-related
JYK05_RS04135	COG2706	6-phosphogluconolactonase activity
JYK05_RS04145	COG0598	Magnesium transport protein CorA
JYK05_RS04150	COG1674	ftsk spoiiie
JYK05_RS04150	COG1674	ftsk spoiiie
JYK05_RS04175	COG0513	Belongs to the DEAD box helicase family
JYK05_RS04180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JYK05_RS04185	COG1054	Belongs to the UPF0176 family
JYK05_RS04215	COG0438	transferase activity, transferring glycosyl groups
JYK05_RS04225	COG1530	ribonuclease E activity
JYK05_RS04235	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JYK05_RS04240	COG0799	negative regulation of ribosome biogenesis
JYK05_RS04250	COG0408	coproporphyrinogen oxidase activity
JYK05_RS04255	COG0151	Belongs to the GarS family
JYK05_RS04260	COG0217	transcriptional regulatory protein
JYK05_RS04265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JYK05_RS04270	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS04285	COG0745	RESPONSE REGULATOR receiver
JYK05_RS04300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JYK05_RS04325	COG0668	transmembrane transport
JYK05_RS04335	COG1522	sequence-specific DNA binding
JYK05_RS04345	COG1289	transmembrane transporter activity
JYK05_RS04350	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JYK05_RS04355	COG1074	ATP-dependent DNA helicase activity
JYK05_RS04365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JYK05_RS04380	COG1620	l-lactate permease
JYK05_RS04400	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JYK05_RS04420	COG4585	Histidine kinase
JYK05_RS04440	COG2197	response regulator
JYK05_RS04445	COG0745	RESPONSE REGULATOR receiver
JYK05_RS04450	COG2814	Major facilitator Superfamily
JYK05_RS04485	COG0477	Major facilitator Superfamily
JYK05_RS04490	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
JYK05_RS04495	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JYK05_RS04495	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JYK05_RS04505	COG1643	Atp-dependent helicase
JYK05_RS04525	COG1058	Belongs to the CinA family
JYK05_RS04525	COG1546	Belongs to the CinA family
JYK05_RS04530	COG3142	Participates in the control of copper homeostasis
JYK05_RS04540	COG0174	glutamine synthetase
JYK05_RS04565	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JYK05_RS04570	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JYK05_RS04575	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JYK05_RS04580	COG2205	protein histidine kinase activity
JYK05_RS04600	COG0402	S-adenosylhomocysteine deaminase activity
JYK05_RS04605	COG0339	signal peptide processing
JYK05_RS04610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JYK05_RS04625	COG4566	intracellular signal transduction
JYK05_RS04635	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JYK05_RS04640	COG0508	dehydrogenase complex catalyzes the overall conversion of
JYK05_RS04645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JYK05_RS04655	COG1686	Belongs to the peptidase S11 family
JYK05_RS04660	COG1414	Transcriptional regulator
JYK05_RS04670	COG1139	Iron-sulfur cluster binding protein
JYK05_RS04690	COG0556	nucleotide-excision repair
JYK05_RS04700	COG4633	Protein conserved in bacteria
JYK05_RS04705	COG0672	)-iron permease
JYK05_RS04715	COG3193	protein, possibly involved in utilization of glycolate and propanediol
JYK05_RS04765	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JYK05_RS04790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JYK05_RS04800	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JYK05_RS04855	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS04890	COG1739	Uncharacterized protein family UPF0029
JYK05_RS04900	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JYK05_RS04915	COG4160	amino acid transport
JYK05_RS04930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JYK05_RS04945	COG1012	belongs to the aldehyde dehydrogenase family
JYK05_RS04950	COG3724	N-succinylarginine dihydrolase activity
JYK05_RS04985	COG0583	DNA-binding transcription factor activity
JYK05_RS04995	COG2135	peptidase activity
JYK05_RS05005	COG0277	FAD linked oxidase domain protein
JYK05_RS05020	COG1295	ribonuclease BN
JYK05_RS05060	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS05070	COG4566	intracellular signal transduction
JYK05_RS05085	COG2945	thiolester hydrolase activity
JYK05_RS05085	COG0596	Alpha beta hydrolase
JYK05_RS05090	COG0251	oxidation-reduction process
JYK05_RS05095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JYK05_RS05105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JYK05_RS05110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JYK05_RS05135	COG0776	regulation of translation
JYK05_RS05175	COG1414	Transcriptional regulator
JYK05_RS05185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JYK05_RS05190	COG0183	Belongs to the thiolase family
JYK05_RS05200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JYK05_RS05205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JYK05_RS05220	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
JYK05_RS05235	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JYK05_RS05245	COG0583	DNA-binding transcription factor activity
JYK05_RS05255	COG2224	Isocitrate lyase
JYK05_RS05260	COG0513	Belongs to the DEAD box helicase family
JYK05_RS05270	COG1214	PFAM Peptidase M22, glycoprotease
JYK05_RS05280	COG1573	uracil-dna glycosylase
JYK05_RS05305	COG0351	phosphomethylpyrimidine kinase
JYK05_RS05310	COG0352	thiamine-phosphate diphosphorylase activity
JYK05_RS05315	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JYK05_RS05320	COG0477	Major facilitator Superfamily
JYK05_RS05325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JYK05_RS05340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JYK05_RS05345	COG0488	(ABC) transporter
JYK05_RS05350	COG0386	Belongs to the glutathione peroxidase family
JYK05_RS05360	COG2890	protein-(glutamine-N5) methyltransferase activity
JYK05_RS05370	COG1393	Belongs to the ArsC family
JYK05_RS05375	COG2171	N-acyltransferase activity
JYK05_RS05400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JYK05_RS05405	COG0242	peptide deformylase activity
JYK05_RS05415	COG1187	pseudouridine synthase activity
JYK05_RS05425	COG0024	Methionine aminopeptidase
JYK05_RS05430	COG0052	Belongs to the universal ribosomal protein uS2 family
JYK05_RS05435	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JYK05_RS05440	COG0528	UMP kinase activity
JYK05_RS05450	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JYK05_RS05460	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JYK05_RS05465	COG0750	zinc metalloprotease
JYK05_RS05475	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
JYK05_RS05480	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JYK05_RS05490	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JYK05_RS05495	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JYK05_RS05500	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JYK05_RS05505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JYK05_RS05510	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JYK05_RS05525	COG0330	HflC and HflK could
JYK05_RS05540	COG2914	Belongs to the UPF0125 (RnfH) family
JYK05_RS05545	COG0697	spore germination
JYK05_RS05560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JYK05_RS05560	COG0519	Catalyzes the synthesis of GMP from XMP
JYK05_RS05580	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
JYK05_RS05585	COG0747	negative chemotaxis
JYK05_RS05590	COG0601	transmembrane transport
JYK05_RS05595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JYK05_RS05600	COG0444	Belongs to the ABC transporter superfamily
JYK05_RS05605	COG4608	Belongs to the ABC transporter superfamily
JYK05_RS05615	COG0590	tRNA wobble adenosine to inosine editing
JYK05_RS05620	COG1619	proteins homologs of microcin C7 resistance protein MccF
JYK05_RS05625	COG1802	Transcriptional regulator
JYK05_RS05630	COG1953	Uracil, thiamine, allantoin
JYK05_RS05645	COG3195	allantoin biosynthetic process
JYK05_RS05645	COG3648	Uricase
JYK05_RS05650	COG4266	Belongs to the allantoicase family
JYK05_RS05660	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
JYK05_RS05670	COG2351	hydroxyisourate hydrolase activity
JYK05_RS05685	COG3845	ABC transporter
JYK05_RS05690	COG4603	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS05695	COG1079	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS05705	COG3360	Dodecin
JYK05_RS05715	COG1970	mechanosensitive ion channel activity
JYK05_RS05755	COG2372	response to copper ion
JYK05_RS05875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JYK05_RS05910	COG2814	Major facilitator Superfamily
JYK05_RS05915	COG0667	Aldo Keto reductase
JYK05_RS05925	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JYK05_RS05935	COG1131	(ABC) transporter
JYK05_RS05955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JYK05_RS05960	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JYK05_RS05965	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JYK05_RS05970	COG4208	sulfate ABC transporter
JYK05_RS05975	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JYK05_RS05980	COG0583	DNA-binding transcription factor activity
JYK05_RS05985	COG0252	asparaginase activity
JYK05_RS05990	COG2084	Dehydrogenase
JYK05_RS05995	COG3622	Belongs to the hyi family
JYK05_RS06000	COG3960	tartronate-semialdehyde synthase activity
JYK05_RS06005	COG0583	DNA-binding transcription factor activity
JYK05_RS06010	COG0360	Binds together with S18 to 16S ribosomal RNA
JYK05_RS06025	COG0359	binds to the 23S rRNA
JYK05_RS06040	COG0306	phosphate transporter
JYK05_RS06045	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS06055	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JYK05_RS06060	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JYK05_RS06065	COG0726	polysaccharide deacetylase
JYK05_RS06070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JYK05_RS06070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JYK05_RS06075	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JYK05_RS06075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JYK05_RS06085	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JYK05_RS06090	COG2076	Multidrug Resistance protein
JYK05_RS06095	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JYK05_RS06100	COG3737	Protein of unknown function (DUF498/DUF598)
JYK05_RS06105	COG0436	Aminotransferase
JYK05_RS06120	COG0488	(ABC) transporter
JYK05_RS06135	COG1914	H( )-stimulated, divalent metal cation uptake system
JYK05_RS06140	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JYK05_RS06145	COG3842	ATPase activity
JYK05_RS06150	COG1176	ABC-type spermidine putrescine transport system, permease component I
JYK05_RS06155	COG1177	transmembrane transport
JYK05_RS06170	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JYK05_RS06175	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JYK05_RS06180	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JYK05_RS06185	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JYK05_RS06190	COG0450	alkyl hydroperoxide reductase
JYK05_RS06245	COG1929	Belongs to the glycerate kinase type-1 family
JYK05_RS06250	COG0544	peptidyl-prolyl cis-trans isomerase activity
JYK05_RS06255	COG0740	serine-type endopeptidase activity
JYK05_RS06260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JYK05_RS06265	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JYK05_RS06270	COG0776	regulation of translation
JYK05_RS06300	COG4181	ATPase activity
JYK05_RS06315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JYK05_RS06320	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JYK05_RS06320	COG0047	phosphoribosylformylglycinamidine synthase activity
JYK05_RS06325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JYK05_RS06335	COG2917	probably involved in intracellular septation
JYK05_RS06340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JYK05_RS06345	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JYK05_RS06350	COG0318	PFAM AMP-dependent synthetase and ligase
JYK05_RS06355	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYK05_RS06355	COG1024	Enoyl-CoA hydratase
JYK05_RS06360	COG1335	isochorismatase
JYK05_RS06375	COG2130	NADP-dependent
JYK05_RS06400	COG0354	folic acid binding
JYK05_RS06410	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JYK05_RS06415	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JYK05_RS06425	COG1247	-acetyltransferase
JYK05_RS06430	COG0084	hydrolase, TatD family'
JYK05_RS06475	COG1879	ABC-type sugar transport system periplasmic component
JYK05_RS06480	COG1129	ABC transporter
JYK05_RS06485	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS06490	COG1609	Transcriptional regulator
JYK05_RS06495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JYK05_RS06500	COG0840	transmembrane signaling receptor activity
JYK05_RS06510	COG2766	serine protein kinase
JYK05_RS06515	COG2718	Belongs to the UPF0229 family
JYK05_RS06520	COG2719	SpoVR family
JYK05_RS06525	COG0628	permease
JYK05_RS06530	COG2962	Rard protein
JYK05_RS06535	COG0667	Aldo Keto reductase
JYK05_RS06545	COG0583	DNA-binding transcription factor activity
JYK05_RS06550	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JYK05_RS06565	COG3795	YCII-related domain
JYK05_RS06575	COG4941	Belongs to the sigma-70 factor family
JYK05_RS06600	COG3206	protein involved in exopolysaccharide biosynthesis
JYK05_RS06600	COG0489	protein tyrosine kinase activity
JYK05_RS06670	COG0583	DNA-binding transcription factor activity
JYK05_RS06675	COG1275	C4-dicarboxylate transporter malic acid transport protein
JYK05_RS06695	COG1953	Uracil, thiamine, allantoin
JYK05_RS06705	COG1295	ribonuclease BN
JYK05_RS06725	COG2974	May be involved in recombination
JYK05_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS06780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JYK05_RS06820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JYK05_RS06865	COG1609	Transcriptional regulator
JYK05_RS06875	COG2271	Major facilitator Superfamily
JYK05_RS06880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JYK05_RS06895	COG2855	membrane
JYK05_RS06905	COG0626	cystathionine gamma-synthase activity
JYK05_RS06915	COG0656	L-ascorbic acid biosynthetic process
JYK05_RS06920	COG0038	chloride channel
JYK05_RS06935	COG2982	Protein involved in outer membrane biogenesis
JYK05_RS06940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JYK05_RS06945	COG0390	transport system, permease component
JYK05_RS06960	COG0784	Response regulator, receiver
JYK05_RS06960	COG2205	protein histidine kinase activity
JYK05_RS06965	COG0784	Response regulator, receiver
JYK05_RS06970	COG4251	negative regulation of phosphorylation
JYK05_RS06990	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JYK05_RS07000	COG0604	alcohol dehydrogenase
JYK05_RS07005	COG0583	DNA-binding transcription factor activity
JYK05_RS07010	COG0560	Phosphoserine phosphatase
JYK05_RS07015	COG0626	cystathionine gamma-synthase activity
JYK05_RS07025	COG0183	Belongs to the thiolase family
JYK05_RS07030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JYK05_RS07035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JYK05_RS07045	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS07050	COG0183	Belongs to the thiolase family
JYK05_RS07055	COG3243	poly(R)-hydroxyalkanoic acid synthase
JYK05_RS07065	COG0564	pseudouridine synthase activity
JYK05_RS07080	COG1199	ATP-dependent helicase activity
JYK05_RS07100	COG2183	response to ionizing radiation
JYK05_RS07105	COG3158	transport of potassium into the cell
JYK05_RS07110	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JYK05_RS07115	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JYK05_RS07120	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JYK05_RS07125	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
JYK05_RS07130	COG0330	HflC and HflK could
JYK05_RS07135	COG0330	HflC and HflK could
JYK05_RS07140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JYK05_RS07150	COG1160	GTP binding
JYK05_RS07155	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JYK05_RS07165	COG0124	histidyl-tRNA synthetase
JYK05_RS07170	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JYK05_RS07180	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JYK05_RS07185	COG0105	UTP biosynthetic process
JYK05_RS07190	COG0670	Belongs to the BI1 family
JYK05_RS07220	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JYK05_RS07230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JYK05_RS07245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JYK05_RS07255	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JYK05_RS07260	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JYK05_RS07280	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JYK05_RS07285	COG3228	Belongs to the MtfA family
JYK05_RS07290	COG0254	rRNA binding
JYK05_RS07300	COG0534	Mate efflux family protein
JYK05_RS07305	COG2373	Large extracellular alpha-helical protein
JYK05_RS07310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JYK05_RS07325	COG0542	response to heat
JYK05_RS07330	COG1959	2 iron, 2 sulfur cluster binding
JYK05_RS07340	COG0314	molybdopterin synthase activity
JYK05_RS07345	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JYK05_RS07350	COG0303	'Molybdopterin
JYK05_RS07360	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JYK05_RS07365	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JYK05_RS07370	COG0167	dihydroorotate dehydrogenase activity
JYK05_RS07375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYK05_RS07380	COG0765	amino acid transport
JYK05_RS07385	COG0673	inositol 2-dehydrogenase activity
JYK05_RS07395	COG0297	glycogen (starch) synthase activity
JYK05_RS07415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JYK05_RS07420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JYK05_RS07430	COG3023	N-Acetylmuramoyl-L-alanine amidase
JYK05_RS07435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JYK05_RS07440	COG0557	exoribonuclease II activity
JYK05_RS07455	COG2814	Major facilitator Superfamily
JYK05_RS07485	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JYK05_RS07490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JYK05_RS07495	COG0508	dehydrogenase complex catalyzes the overall conversion of
JYK05_RS07500	COG0567	Dehydrogenase, E1 component
JYK05_RS07520	COG1566	PFAM secretion protein HlyD family protein
JYK05_RS07525	COG2814	Major facilitator Superfamily
JYK05_RS07530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JYK05_RS07535	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JYK05_RS07540	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JYK05_RS07545	COG2251	uridine kinase activity
JYK05_RS07545	COG0195	Participates in both transcription termination and antitermination
JYK05_RS07550	COG0779	Required for maturation of 30S ribosomal subunits
JYK05_RS07555	COG1187	pseudouridine synthase activity
JYK05_RS07560	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JYK05_RS07565	COG0436	Aminotransferase
JYK05_RS07570	COG0583	DNA-binding transcription factor activity
JYK05_RS07640	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JYK05_RS07645	COG1752	Esterase of the alpha-beta hydrolase superfamily
JYK05_RS07650	COG2010	Cytochrome c
JYK05_RS07650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JYK05_RS07665	COG2975	iron-sulfur cluster assembly
JYK05_RS07670	COG0633	Ferredoxin
JYK05_RS07675	COG0443	Heat shock 70 kDa protein
JYK05_RS07680	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JYK05_RS07690	COG0822	iron-sulfur transferase activity
JYK05_RS07695	COG1104	cysteine desulfurase activity
JYK05_RS07705	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JYK05_RS07720	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JYK05_RS07755	COG0587	DNA-directed DNA polymerase activity
JYK05_RS07815	COG2866	Carboxypeptidase
JYK05_RS07820	COG3022	response to hydroperoxide
JYK05_RS07830	COG0436	Aminotransferase
JYK05_RS07835	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYK05_RS07840	COG1024	Enoyl-CoA hydratase
JYK05_RS07860	COG0625	glutathione transferase activity
JYK05_RS07875	COG0494	nUDIX hydrolase
JYK05_RS07885	COG1007	ATP synthesis coupled electron transport
JYK05_RS07900	COG0713	ATP synthesis coupled electron transport
JYK05_RS07910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JYK05_RS07915	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JYK05_RS07920	COG1034	ATP synthesis coupled electron transport
JYK05_RS07930	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
JYK05_RS07935	COG0649	NAD binding
JYK05_RS07940	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JYK05_RS07945	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JYK05_RS07950	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JYK05_RS07965	COG0149	triose-phosphate isomerase activity
JYK05_RS07970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JYK05_RS07970	COG3321	synthase
JYK05_RS07970	COG4221	oxidoreductase activity
JYK05_RS07970	COG0604	alcohol dehydrogenase
JYK05_RS07975	COG1185	polyribonucleotide nucleotidyltransferase activity
JYK05_RS07980	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JYK05_RS07985	COG0683	leucine binding
JYK05_RS07995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JYK05_RS08000	COG0791	NLP P60 protein
JYK05_RS08005	COG4172	Belongs to the ABC transporter superfamily
JYK05_RS08010	COG4239	(ABC) transporter, permease
JYK05_RS08015	COG4174	ABC transporter (Permease)
JYK05_RS08020	COG4166	transmembrane transport
JYK05_RS08060	COG3052	prosthetic group binding
JYK05_RS08090	COG0501	Belongs to the peptidase M48B family
JYK05_RS08100	COG0527	aspartate kinase activity
JYK05_RS08105	COG0037	tRNA processing
JYK05_RS08115	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JYK05_RS08130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JYK05_RS08135	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JYK05_RS08140	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JYK05_RS08145	COG1045	serine acetyltransferase
JYK05_RS08150	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
JYK05_RS08155	COG0483	inositol monophosphate 1-phosphatase activity
JYK05_RS08170	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JYK05_RS08185	COG2850	peptidyl-arginine hydroxylation
JYK05_RS08195	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JYK05_RS08200	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
JYK05_RS08205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JYK05_RS08215	COG0180	Tryptophanyl-tRNA synthetase
JYK05_RS08220	COG1994	Peptidase M50
JYK05_RS08225	COG0009	L-threonylcarbamoyladenylate synthase
JYK05_RS08230	COG0613	PHP domain protein
JYK05_RS08235	COG0596	Alpha beta hydrolase
JYK05_RS08240	COG2833	Protein of unknown function (DUF455)
JYK05_RS08250	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JYK05_RS08260	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JYK05_RS08275	COG0504	CTP synthase activity
JYK05_RS08290	COG0084	hydrolase, TatD family'
JYK05_RS08295	COG1136	(ABC) transporter
JYK05_RS08310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JYK05_RS08320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JYK05_RS08325	COG1715	Restriction endonuclease
JYK05_RS08335	COG1183	phosphatidylcholine synthase activity
JYK05_RS08340	COG0688	phosphatidylethanolamine metabolic process
JYK05_RS08345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JYK05_RS08350	COG0440	acetolactate synthase activity
JYK05_RS08355	COG0028	Belongs to the TPP enzyme family
JYK05_RS08420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JYK05_RS08430	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JYK05_RS08445	COG1271	oxidase subunit
JYK05_RS08450	COG1294	oxidase, subunit
JYK05_RS08465	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JYK05_RS08470	COG5001	Diguanylate cyclase
JYK05_RS08470	COG3300	MHYT domain
JYK05_RS08480	COG0840	transmembrane signaling receptor activity
JYK05_RS08485	COG2223	nitrite transmembrane transporter activity
JYK05_RS08500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JYK05_RS08515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JYK05_RS08520	COG0210	DNA helicase
JYK05_RS08525	COG0525	valine-tRNA ligase activity
JYK05_RS08530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JYK05_RS08535	COG0425	Belongs to the sulfur carrier protein TusA family
JYK05_RS08550	COG0673	inositol 2-dehydrogenase activity
JYK05_RS08555	COG0673	inositol 2-dehydrogenase activity
JYK05_RS08570	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS08575	COG1129	ABC transporter
JYK05_RS08585	COG3962	Belongs to the TPP enzyme family
JYK05_RS08595	COG3718	enzyme involved in inositol metabolism
JYK05_RS08620	COG0824	Thioesterase
JYK05_RS08640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JYK05_RS08645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JYK05_RS08655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JYK05_RS08660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYK05_RS08665	COG0494	nUDIX hydrolase
JYK05_RS08685	COG0582	viral genome integration into host DNA
JYK05_RS08720	COG1475	DNA binding
JYK05_RS08775	COG0587	DNA-directed DNA polymerase activity
JYK05_RS08810	COG1968	undecaprenyl-diphosphatase activity
JYK05_RS08820	COG4942	peptidase
JYK05_RS08865	COG0745	RESPONSE REGULATOR receiver
JYK05_RS08880	COG0581	inorganic phosphate transmembrane transporter activity
JYK05_RS08885	COG0573	inorganic phosphate transmembrane transporter activity
JYK05_RS08890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JYK05_RS08895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JYK05_RS08900	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JYK05_RS08905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JYK05_RS08910	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JYK05_RS08915	COG1534	Rna-binding protein
JYK05_RS08925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JYK05_RS08930	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JYK05_RS08935	COG0505	Belongs to the CarA family
JYK05_RS08945	COG1388	LysM domain
JYK05_RS08945	COG0741	lytic transglycosylase activity
JYK05_RS08950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JYK05_RS08955	COG2226	methyltransferase
JYK05_RS08960	COG0328	RNA-DNA hybrid ribonuclease activity
JYK05_RS08965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JYK05_RS08985	COG0438	transferase activity, transferring glycosyl groups
JYK05_RS08990	COG1132	(ABC) transporter
JYK05_RS08995	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JYK05_RS09005	COG1999	signal sequence binding
JYK05_RS09015	COG2153	protein acetylation
JYK05_RS09035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JYK05_RS09040	COG0322	excinuclease ABC activity
JYK05_RS09050	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JYK05_RS09060	COG2204	response regulator
JYK05_RS09065	COG1472	Belongs to the glycosyl hydrolase 3 family
JYK05_RS09070	COG0736	holo-[acyl-carrier-protein] synthase activity
JYK05_RS09080	COG1381	Involved in DNA repair and RecF pathway recombination
JYK05_RS09085	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JYK05_RS09090	COG0571	ribonuclease III activity
JYK05_RS09095	COG0681	Belongs to the peptidase S26 family
JYK05_RS09100	COG0481	GTPase activity
JYK05_RS09110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JYK05_RS09125	COG1595	DNA-templated transcription, initiation
JYK05_RS09170	COG1399	metal-binding, possibly nucleic acid-binding protein
JYK05_RS09185	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JYK05_RS09185	COG0616	signal peptide processing
JYK05_RS09195	COG0546	phosphoglycolate phosphatase activity
JYK05_RS09205	COG1530	ribonuclease E activity
JYK05_RS09210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JYK05_RS09220	COG0303	'Molybdopterin
JYK05_RS09235	COG1322	Protein conserved in bacteria
JYK05_RS09240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYK05_RS09260	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JYK05_RS09285	COG1139	Iron-sulfur cluster binding protein
JYK05_RS09290	COG0247	lactate metabolic process
JYK05_RS09295	COG2186	Transcriptional regulator
JYK05_RS09300	COG3045	CreA protein
JYK05_RS09345	COG0534	Mate efflux family protein
JYK05_RS09350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JYK05_RS09355	COG0114	fumarate hydratase activity
JYK05_RS09395	COG0312	modulator of DNA gyrase
JYK05_RS09400	COG3028	Belongs to the UPF0307 family
JYK05_RS09405	COG0521	Mo-molybdopterin cofactor biosynthetic process
JYK05_RS09410	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JYK05_RS09415	COG0501	Belongs to the peptidase M48B family
JYK05_RS09420	COG1162	GTPase activity
JYK05_RS09430	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JYK05_RS09440	COG0335	large ribosomal subunit rRNA binding
JYK05_RS09445	COG0336	Belongs to the RNA methyltransferase TrmD family
JYK05_RS09450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JYK05_RS09475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JYK05_RS09480	COG1960	acyl-CoA dehydrogenase activity
JYK05_RS09500	COG2011	ABC-type metal ion transport system permease component
JYK05_RS09510	COG0123	including yeast histone deacetylase and acetoin utilization protein
JYK05_RS09515	COG2951	lytic endotransglycosylase activity
JYK05_RS09530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JYK05_RS09535	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JYK05_RS09545	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JYK05_RS09555	COG0776	regulation of translation
JYK05_RS09575	COG0287	Prephenate dehydrogenase
JYK05_RS09605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JYK05_RS09610	COG0546	phosphoglycolate phosphatase activity
JYK05_RS09635	COG1910	domain protein
JYK05_RS09650	COG3383	formate dehydrogenase (NAD+) activity
JYK05_RS09665	COG1230	cation diffusion facilitator family transporter
JYK05_RS09670	COG0640	Transcriptional regulator
JYK05_RS09700	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JYK05_RS09705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JYK05_RS09705	COG4651	solute:proton antiporter activity
JYK05_RS09715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JYK05_RS09715	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JYK05_RS09725	COG2827	Endonuclease containing a URI domain
JYK05_RS09730	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JYK05_RS09735	COG1012	belongs to the aldehyde dehydrogenase family
JYK05_RS09760	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JYK05_RS09775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYK05_RS09780	COG0765	amino acid transport
JYK05_RS09785	COG0765	amino acid transport
JYK05_RS09790	COG1126	abc transporter atp-binding protein
JYK05_RS09795	COG0831	urea catabolic process
JYK05_RS09800	COG0832	Belongs to the urease beta subunit family
JYK05_RS09805	COG0804	urea catabolic process
JYK05_RS09810	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JYK05_RS09815	COG0830	nickel cation binding
JYK05_RS09865	COG0438	transferase activity, transferring glycosyl groups
JYK05_RS09870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JYK05_RS09885	COG0438	transferase activity, transferring glycosyl groups
JYK05_RS09890	COG2244	polysaccharide biosynthetic process
JYK05_RS09910	COG0438	transferase activity, transferring glycosyl groups
JYK05_RS09935	COG0297	glycogen (starch) synthase activity
JYK05_RS09945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JYK05_RS09950	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JYK05_RS09955	COG3206	protein involved in exopolysaccharide biosynthesis
JYK05_RS09955	COG0489	protein tyrosine kinase activity
JYK05_RS09970	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
JYK05_RS09970	COG0662	Cupin 2, conserved barrel domain protein
JYK05_RS10015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JYK05_RS10045	COG0463	Glycosyl transferase, family 2
JYK05_RS10055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JYK05_RS10075	COG0463	Glycosyl transferase, family 2
JYK05_RS10075	COG1216	Glycosyl transferase, family 2
JYK05_RS10130	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JYK05_RS10150	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JYK05_RS10155	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JYK05_RS10160	COG1678	Uncharacterized ACR, COG1678
JYK05_RS10165	COG0415	Belongs to the DNA photolyase family
JYK05_RS10175	COG1773	rubredoxin
JYK05_RS10195	COG0459	protein refolding
JYK05_RS10200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JYK05_RS10205	COG0438	transferase activity, transferring glycosyl groups
JYK05_RS10265	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JYK05_RS10280	COG2188	Transcriptional regulator
JYK05_RS10285	COG2814	Major facilitator Superfamily
JYK05_RS10295	COG0546	phosphoglycolate phosphatase activity
JYK05_RS10295	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JYK05_RS10325	COG1570	exodeoxyribonuclease VII activity
JYK05_RS10335	COG2835	tetraacyldisaccharide 4'-kinase activity
JYK05_RS10345	COG0563	adenylate kinase activity
JYK05_RS10360	COG0728	peptidoglycan biosynthetic process
JYK05_RS10365	COG0268	Binds directly to 16S ribosomal RNA
JYK05_RS10375	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JYK05_RS10390	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JYK05_RS10395	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JYK05_RS10400	COG1960	acyl-CoA dehydrogenase activity
JYK05_RS10405	COG4974	Belongs to the 'phage' integrase family
JYK05_RS10410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JYK05_RS10415	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JYK05_RS10420	COG0802	atpase or kinase
JYK05_RS10425	COG0860	N-Acetylmuramoyl-L-alanine amidase
JYK05_RS10440	COG1741	Belongs to the pirin family
JYK05_RS10450	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JYK05_RS10455	COG0259	pyridoxamine-phosphate oxidase activity
JYK05_RS10460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JYK05_RS10470	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JYK05_RS10475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JYK05_RS10480	COG1522	sequence-specific DNA binding
JYK05_RS10495	COG3483	tryptophan 2,3-dioxygenase activity
JYK05_RS10505	COG1960	acyl-CoA dehydrogenase activity
JYK05_RS10525	COG4969	Belongs to the N-Me-Phe pilin family
JYK05_RS10560	COG4221	oxidoreductase activity
JYK05_RS10565	COG0824	Thioesterase
JYK05_RS10585	COG0823	Involved in the tonB-independent uptake of proteins
JYK05_RS10605	COG4191	Histidine kinase
JYK05_RS10610	COG2015	COG2015, Alkyl sulfatase and related hydrolases
JYK05_RS10620	COG4566	intracellular signal transduction
JYK05_RS10635	COG1960	acyl-CoA dehydrogenase activity
JYK05_RS10640	COG0183	Belongs to the thiolase family
JYK05_RS10645	COG1024	Enoyl-CoA hydratase
JYK05_RS10645	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYK05_RS10665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JYK05_RS10670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JYK05_RS10675	COG1960	acyl-CoA dehydrogenase activity
JYK05_RS10680	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS10695	COG1960	acyl-CoA dehydrogenase activity
JYK05_RS10700	COG0183	Belongs to the thiolase family
JYK05_RS10710	COG1960	acyl-CoA dehydrogenase activity
JYK05_RS10715	COG0183	Belongs to the thiolase family
JYK05_RS10720	COG1024	Enoyl-CoA hydratase
JYK05_RS10725	COG2909	trisaccharide binding
JYK05_RS10735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JYK05_RS10745	COG0420	3'-5' exonuclease activity
JYK05_RS10755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JYK05_RS10760	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JYK05_RS10765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JYK05_RS10770	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JYK05_RS10780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JYK05_RS10790	COG3265	gluconokinase activity
JYK05_RS10825	COG0800	Aldolase
JYK05_RS10840	COG1981	membrane
JYK05_RS10845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JYK05_RS10850	COG1466	dna polymerase III delta subunit
JYK05_RS10855	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
JYK05_RS10860	COG0495	leucyl-tRNA aminoacylation
JYK05_RS10880	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JYK05_RS10885	COG0735	belongs to the Fur family
JYK05_RS10895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JYK05_RS10900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JYK05_RS10910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JYK05_RS10935	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JYK05_RS10940	COG1546	Belongs to the CinA family
JYK05_RS10945	COG0284	orotidine-5'-phosphate decarboxylase activity
JYK05_RS10970	COG1129	ABC transporter
JYK05_RS10980	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS10985	COG0800	Aldolase
JYK05_RS10990	COG3734	2-keto-3-deoxy-galactonokinase
JYK05_RS10995	COG1414	Transcriptional regulator
JYK05_RS11000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JYK05_RS11005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JYK05_RS11010	COG0557	exoribonuclease II activity
JYK05_RS11015	COG3150	esterase
JYK05_RS11020	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JYK05_RS11030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JYK05_RS11035	COG0511	ligase activity, forming carbon-carbon bonds
JYK05_RS11040	COG0439	Biotin carboxylase
JYK05_RS11055	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JYK05_RS11060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JYK05_RS11085	COG0477	Major facilitator Superfamily
JYK05_RS11100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JYK05_RS11105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JYK05_RS11110	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JYK05_RS11115	COG2095	MarC family integral membrane protein
JYK05_RS11120	COG0442	prolyl-tRNA aminoacylation
JYK05_RS11125	COG0494	nUDIX hydrolase
JYK05_RS11150	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JYK05_RS11155	COG0142	geranyltranstransferase activity
JYK05_RS11165	COG4536	flavin adenine dinucleotide binding
JYK05_RS11170	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JYK05_RS11180	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JYK05_RS11190	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
JYK05_RS11195	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JYK05_RS11200	COG0494	nUDIX hydrolase
JYK05_RS11210	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JYK05_RS11215	COG0653	protein targeting
JYK05_RS11225	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JYK05_RS11230	COG0678	peroxiredoxin activity
JYK05_RS11245	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JYK05_RS11250	COG1181	Belongs to the D-alanine--D-alanine ligase family
JYK05_RS11255	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JYK05_RS11260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JYK05_RS11280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JYK05_RS11285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JYK05_RS11295	COG3116	cell division
JYK05_RS11300	COG0275	rRNA processing
JYK05_RS11310	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
JYK05_RS11315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JYK05_RS11320	COG0318	PFAM AMP-dependent synthetase and ligase
JYK05_RS11325	COG0243	molybdopterin cofactor binding
JYK05_RS11330	COG1473	amidohydrolase
JYK05_RS11360	COG1024	Enoyl-CoA hydratase
JYK05_RS11370	COG1024	Enoyl-CoA hydratase
JYK05_RS11375	COG2050	protein possibly involved in aromatic compounds catabolism
JYK05_RS11385	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
JYK05_RS11390	COG2967	ApaG domain
JYK05_RS11395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JYK05_RS11400	COG0546	phosphoglycolate phosphatase activity
JYK05_RS11415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JYK05_RS11420	COG0134	indole-3-glycerol-phosphate synthase activity
JYK05_RS11425	COG3025	triphosphatase activity
JYK05_RS11430	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JYK05_RS11445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JYK05_RS11450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JYK05_RS11455	COG0012	GTP binding
JYK05_RS11465	COG0488	(ABC) transporter
JYK05_RS11480	COG0006	proline dipeptidase activity
JYK05_RS11495	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JYK05_RS11500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JYK05_RS11505	COG2890	protein-(glutamine-N5) methyltransferase activity
JYK05_RS11510	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JYK05_RS11520	COG3384	dioxygenase
JYK05_RS11525	COG0531	amino acid
JYK05_RS11530	COG1278	Cold shock
JYK05_RS11535	COG0443	Heat shock 70 kDa protein
JYK05_RS11540	COG2271	Major facilitator Superfamily
JYK05_RS11575	COG2186	Transcriptional regulator
JYK05_RS11580	COG0246	Mannitol dehydrogenase
JYK05_RS11585	COG2271	Major facilitator Superfamily
JYK05_RS11590	COG2721	sulfolactate sulfo-lyase activity
JYK05_RS11595	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JYK05_RS11630	COG2969	positive regulation of protein catabolic process
JYK05_RS11635	COG0625	glutathione transferase activity
JYK05_RS11640	COG2857	Cytochrome c1
JYK05_RS11645	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JYK05_RS11650	COG0723	plastoquinol--plastocyanin reductase activity
JYK05_RS11655	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JYK05_RS11660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JYK05_RS11665	COG0805	protein transport
JYK05_RS11670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JYK05_RS11675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JYK05_RS11690	COG0140	phosphoribosyl-ATP diphosphatase activity
JYK05_RS11700	COG0107	imidazoleglycerol-phosphate synthase activity
JYK05_RS11705	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JYK05_RS11715	COG2095	MarC family integral membrane protein
JYK05_RS11720	COG0131	Imidazoleglycerol-phosphate dehydratase
JYK05_RS11740	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JYK05_RS11745	COG0271	Belongs to the BolA IbaG family
JYK05_RS11750	COG0842	Transport permease protein
JYK05_RS11755	COG1131	(ABC) transporter
JYK05_RS11775	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JYK05_RS11780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JYK05_RS11785	COG1127	ABC transporter
JYK05_RS11810	COG4178	(ABC) transporter
JYK05_RS11820	COG0070	glutamate synthase
JYK05_RS11820	COG0069	glutamate synthase activity
JYK05_RS11820	COG0067	glutamate synthase
JYK05_RS11840	COG0584	glycerophosphoryl diester phosphodiesterase
JYK05_RS11850	COG0395	ABC-type sugar transport system, permease component
JYK05_RS11860	COG1653	transport
JYK05_RS11865	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JYK05_RS11905	COG1965	Belongs to the frataxin family
JYK05_RS11920	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JYK05_RS11925	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JYK05_RS11930	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JYK05_RS11935	COG1333	cytochrome c biogenesis protein
JYK05_RS11945	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JYK05_RS11955	COG4232	protein-disulfide reductase activity
JYK05_RS11970	COG0202	RNA polymerase activity
JYK05_RS11980	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JYK05_RS11985	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JYK05_RS12000	COG0201	protein transport
JYK05_RS12005	COG0200	Binds to the 23S rRNA
JYK05_RS12015	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JYK05_RS12025	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JYK05_RS12030	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JYK05_RS12040	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JYK05_RS12045	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JYK05_RS12050	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JYK05_RS12055	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JYK05_RS12060	COG0255	Belongs to the universal ribosomal protein uL29 family
JYK05_RS12070	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JYK05_RS12075	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JYK05_RS12080	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JYK05_RS12090	COG0089	rRNA binding
JYK05_RS12095	COG0088	Forms part of the polypeptide exit tunnel
JYK05_RS12100	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JYK05_RS12105	COG0051	transcription antitermination factor activity, RNA binding
JYK05_RS12120	COG0049	tRNA binding
JYK05_RS12125	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JYK05_RS12130	COG0514	ATP-dependent DNA helicase (RecQ)
JYK05_RS12135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JYK05_RS12140	COG0085	RNA polymerase activity
JYK05_RS12145	COG0222	ribosome binding
JYK05_RS12150	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JYK05_RS12155	COG0081	regulation of translation
JYK05_RS12170	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JYK05_RS12230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JYK05_RS12240	COG2271	Major facilitator Superfamily
JYK05_RS12245	COG3396	Phenylacetate-CoA oxygenase
JYK05_RS12250	COG3460	Phenylacetate-CoA oxygenase
JYK05_RS12255	COG3396	Phenylacetate-CoA oxygenase
JYK05_RS12260	COG2151	metal-sulfur cluster biosynthetic enzyme
JYK05_RS12265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JYK05_RS12285	COG1522	sequence-specific DNA binding
JYK05_RS12315	COG2814	Major facilitator Superfamily
JYK05_RS12320	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JYK05_RS12325	COG2197	response regulator
JYK05_RS12330	COG1881	PFAM PEBP family protein
JYK05_RS12340	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JYK05_RS12355	COG1280	lysine exporter protein (LysE YggA)
JYK05_RS12360	COG2084	Dehydrogenase
JYK05_RS12390	COG0579	oxidoreductase
JYK05_RS12395	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JYK05_RS12405	COG3568	Endonuclease Exonuclease Phosphatase
JYK05_RS12410	COG0745	RESPONSE REGULATOR receiver
JYK05_RS12420	COG0251	oxidation-reduction process
JYK05_RS12455	COG1181	Belongs to the D-alanine--D-alanine ligase family
JYK05_RS12460	COG2175	clavaminate synthase activity
JYK05_RS12465	COG4865	methylaspartate mutase activity
JYK05_RS12470	COG0527	aspartate kinase activity
JYK05_RS12475	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JYK05_RS12485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYK05_RS12490	COG0583	DNA-binding transcription factor activity
JYK05_RS12495	COG2084	Dehydrogenase
JYK05_RS12500	COG3836	Belongs to the HpcH HpaI aldolase family
JYK05_RS12505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JYK05_RS12510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JYK05_RS12515	COG0037	tRNA processing
JYK05_RS12525	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS12540	COG0617	tRNA 3'-terminal CCA addition
JYK05_RS12555	COG0741	lytic transglycosylase activity
JYK05_RS12560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JYK05_RS12570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JYK05_RS12575	COG1984	allophanate hydrolase subunit 2
JYK05_RS12580	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JYK05_RS12600	COG4608	Belongs to the ABC transporter superfamily
JYK05_RS12605	COG0444	Belongs to the ABC transporter superfamily
JYK05_RS12610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JYK05_RS12615	COG0601	transmembrane transport
JYK05_RS12620	COG0747	negative chemotaxis
JYK05_RS12625	COG1215	transferase activity, transferring glycosyl groups
JYK05_RS12630	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JYK05_RS12635	COG1950	PFAM Membrane protein of
JYK05_RS12640	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JYK05_RS12655	COG0583	DNA-binding transcription factor activity
JYK05_RS12665	COG1960	acyl-CoA dehydrogenase activity
JYK05_RS12700	COG2257	FlhB HrpN YscU SpaS Family
JYK05_RS12755	COG1580	Controls the rotational direction of flagella during chemotaxis
JYK05_RS12765	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JYK05_RS12780	COG1987	bacterial-type flagellum assembly
JYK05_RS12800	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JYK05_RS12810	COG1706	bacterial-type flagellum-dependent cell motility
JYK05_RS12830	COG1749	Flagellar hook protein flgE
JYK05_RS12840	COG1558	bacterial-type flagellum-dependent cell motility
JYK05_RS12870	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JYK05_RS12875	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JYK05_RS12890	COG1760	l-serine dehydratase
JYK05_RS12900	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JYK05_RS12900	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JYK05_RS12905	COG0509	glycine decarboxylation via glycine cleavage system
JYK05_RS12910	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JYK05_RS12920	COG0673	inositol 2-dehydrogenase activity
JYK05_RS12925	COG0210	DNA helicase
JYK05_RS12930	COG3245	cytochrome
JYK05_RS12965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JYK05_RS12970	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS12990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JYK05_RS13000	COG1215	transferase activity, transferring glycosyl groups
JYK05_RS13015	COG1191	sigma factor activity
JYK05_RS13035	COG0683	leucine binding
JYK05_RS13040	COG0506	proline dehydrogenase activity
JYK05_RS13040	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JYK05_RS13040	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JYK05_RS13050	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JYK05_RS13055	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JYK05_RS13065	COG0657	acetylesterase activity
JYK05_RS13070	COG0318	PFAM AMP-dependent synthetase and ligase
JYK05_RS13075	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JYK05_RS13080	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JYK05_RS13085	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JYK05_RS13095	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JYK05_RS13100	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JYK05_RS13110	COG0356	it plays a direct role in the translocation of protons across the membrane
JYK05_RS13120	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JYK05_RS13125	COG1475	DNA binding
JYK05_RS13130	COG1192	Involved in chromosome partitioning
JYK05_RS13140	COG0445	tRNA wobble uridine modification
JYK05_RS13200	COG0583	DNA-binding transcription factor activity
JYK05_RS13210	COG1522	sequence-specific DNA binding
JYK05_RS13220	COG0642	Histidine kinase
JYK05_RS13230	COG1902	pentaerythritol trinitrate reductase activity
JYK05_RS13235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JYK05_RS13235	COG0519	Catalyzes the synthesis of GMP from XMP
JYK05_RS13245	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JYK05_RS13255	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JYK05_RS13255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JYK05_RS13285	COG1459	type II secretion system
JYK05_RS13345	COG1846	Transcriptional regulator
JYK05_RS13350	COG2814	Major facilitator Superfamily
JYK05_RS13365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JYK05_RS13365	COG2169	Transcriptional regulator
JYK05_RS13370	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JYK05_RS13375	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JYK05_RS13385	COG0523	cobalamin synthesis protein
JYK05_RS13390	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JYK05_RS13395	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JYK05_RS13405	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JYK05_RS13410	COG1560	Kdo2-lipid A biosynthetic process
JYK05_RS13435	COG0668	transmembrane transport
JYK05_RS13440	COG0667	Aldo Keto reductase
JYK05_RS13450	COG3851	Histidine kinase
JYK05_RS13460	COG0531	amino acid
JYK05_RS13495	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JYK05_RS13505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JYK05_RS13515	COG2814	Major facilitator Superfamily
JYK05_RS13545	COG2916	Histone family protein nucleoid-structuring protein H-NS
JYK05_RS13555	COG1522	sequence-specific DNA binding
JYK05_RS13565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JYK05_RS13580	COG0792	nuclease activity
JYK05_RS13585	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JYK05_RS13630	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JYK05_RS13655	COG1280	lysine exporter protein (LysE YggA)
JYK05_RS13665	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JYK05_RS13680	COG0706	membrane insertase activity
JYK05_RS13685	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JYK05_RS13690	COG0594	ribonuclease P activity
JYK05_RS13710	COG1192	Involved in chromosome partitioning
JYK05_RS13715	COG1042	CoA-binding domain protein
JYK05_RS13715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JYK05_RS13715	COG0045	succinate-CoA ligase (ADP-forming) activity
JYK05_RS13740	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS13755	COG0840	transmembrane signaling receptor activity
JYK05_RS13765	COG1285	pathogenesis
JYK05_RS13780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JYK05_RS13785	COG4175	Glycine betaine
JYK05_RS13800	COG0235	Class ii aldolase
JYK05_RS13815	COG1760	l-serine dehydratase
JYK05_RS13830	COG0446	pyridine nucleotide-disulphide oxidoreductase
JYK05_RS13830	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JYK05_RS13860	COG0477	Major facilitator Superfamily
JYK05_RS13890	COG0446	pyridine nucleotide-disulphide oxidoreductase
JYK05_RS13890	COG1902	pentaerythritol trinitrate reductase activity
JYK05_RS13895	COG2181	nitrate reductase activity
JYK05_RS13895	COG0247	lactate metabolic process
JYK05_RS13900	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JYK05_RS13915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JYK05_RS13920	COG2113	Glycine betaine
JYK05_RS13940	COG2217	Heavy metal translocating P-type atpase
JYK05_RS13965	COG2814	Major facilitator Superfamily
JYK05_RS13970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYK05_RS13975	COG0436	Aminotransferase
JYK05_RS13980	COG0583	DNA-binding transcription factor activity
JYK05_RS14000	COG3795	YCII-related domain
JYK05_RS14005	COG1609	Transcriptional regulator
JYK05_RS14015	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS14020	COG1879	ABC-type sugar transport system periplasmic component
JYK05_RS14030	COG0673	inositol 2-dehydrogenase activity
JYK05_RS14045	COG3209	COG3209 Rhs family protein
JYK05_RS14095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JYK05_RS14115	COG2186	Transcriptional regulator
JYK05_RS14120	COG2084	Dehydrogenase
JYK05_RS14125	COG3622	Belongs to the hyi family
JYK05_RS14130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JYK05_RS14140	COG0492	ferredoxin-NADP+ reductase activity
JYK05_RS14155	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
JYK05_RS14160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JYK05_RS14170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JYK05_RS14175	COG2079	MmgE PrpD family protein
JYK05_RS14195	COG0039	L-malate dehydrogenase activity
JYK05_RS14200	COG2188	Transcriptional regulator
JYK05_RS14205	COG2009	succinate dehydrogenase
JYK05_RS14215	COG1053	succinate dehydrogenase
JYK05_RS14220	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JYK05_RS14225	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
JYK05_RS14230	COG0372	Belongs to the citrate synthase family
JYK05_RS14235	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JYK05_RS14265	COG0101	tRNA pseudouridine synthase activity
JYK05_RS14270	COG0135	phosphoribosylanthranilate isomerase activity
JYK05_RS14275	COG0133	tryptophan synthase activity
JYK05_RS14290	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JYK05_RS14295	COG0285	dihydrofolate synthase activity
JYK05_RS14340	COG0438	transferase activity, transferring glycosyl groups
JYK05_RS14370	COG1253	flavin adenine dinucleotide binding
JYK05_RS14380	COG1640	4-alpha-glucanotransferase
JYK05_RS14385	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JYK05_RS14395	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JYK05_RS14400	COG0366	Alpha amylase catalytic
JYK05_RS14405	COG0366	Alpha amylase catalytic
JYK05_RS14410	COG0297	glycogen (starch) synthase activity
JYK05_RS14435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JYK05_RS14445	COG5654	RES domain protein
JYK05_RS14450	COG5642	Protein of unknown function (DUF2384)
JYK05_RS14475	COG0306	phosphate transporter
JYK05_RS14505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JYK05_RS14515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JYK05_RS14525	COG1611	Belongs to the LOG family
JYK05_RS14535	COG1252	NADH dehydrogenase
JYK05_RS14540	COG0412	Dienelactone hydrolase
JYK05_RS14560	COG0142	geranyltranstransferase activity
JYK05_RS14565	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JYK05_RS14570	COG1469	GTP cyclohydrolase I activity
JYK05_RS14575	COG0583	DNA-binding transcription factor activity
JYK05_RS14590	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JYK05_RS14595	COG2081	HI0933 family
JYK05_RS14610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JYK05_RS14725	COG5634	Uncharacterized conserved protein (DUF2278)
JYK05_RS14755	COG3436	PFAM IS66 Orf2 family protein
JYK05_RS14800	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JYK05_RS14820	COG2916	Histone family protein nucleoid-structuring protein H-NS
JYK05_RS14850	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JYK05_RS14850	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JYK05_RS14860	COG0542	response to heat
JYK05_RS14985	COG1012	belongs to the aldehyde dehydrogenase family
JYK05_RS15005	COG0583	DNA-binding transcription factor activity
JYK05_RS15010	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JYK05_RS15020	COG1802	Transcriptional regulator
JYK05_RS15040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JYK05_RS15065	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JYK05_RS15100	COG0596	Alpha beta hydrolase
JYK05_RS15105	COG0534	Mate efflux family protein
JYK05_RS15110	COG1742	UPF0060 membrane protein
JYK05_RS15120	COG0477	Major facilitator Superfamily
JYK05_RS15140	COG1960	acyl-CoA dehydrogenase activity
JYK05_RS15145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JYK05_RS15160	COG0628	permease
JYK05_RS15165	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYK05_RS15185	COG1131	(ABC) transporter
JYK05_RS15190	COG0842	Transport permease protein
JYK05_RS15220	COG1473	amidohydrolase
JYK05_RS15225	COG0840	transmembrane signaling receptor activity
JYK05_RS15225	COG0840	transmembrane signaling receptor activity
JYK05_RS15245	COG1573	uracil-dna glycosylase
JYK05_RS15255	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JYK05_RS15260	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JYK05_RS15265	COG2080	2 iron, 2 sulfur cluster binding
JYK05_RS15300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYK05_RS15300	COG2205	protein histidine kinase activity
JYK05_RS15335	COG3842	ATPase activity
JYK05_RS15350	COG0058	SHG alpha-glucan phosphorylase activity
JYK05_RS15370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JYK05_RS15370	COG3008	intermembrane lipid transfer
JYK05_RS15375	COG2995	paraquat-inducible protein a
JYK05_RS15390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JYK05_RS15395	COG0640	Transcriptional regulator
JYK05_RS15400	COG1902	pentaerythritol trinitrate reductase activity
JYK05_RS15405	COG2985	domain, Protein
JYK05_RS15435	COG2271	Major facilitator Superfamily
JYK05_RS15445	COG1309	transcriptional regulator
JYK05_RS15450	COG1960	acyl-CoA dehydrogenase activity
JYK05_RS15455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JYK05_RS15480	COG3485	protocatechuate 3,4-dioxygenase
JYK05_RS15485	COG3485	protocatechuate 3,4-dioxygenase
JYK05_RS15490	COG0583	DNA-binding transcription factor activity
JYK05_RS15495	COG0745	RESPONSE REGULATOR receiver
JYK05_RS15510	COG2200	EAL domain
JYK05_RS15510	COG2199	diguanylate cyclase activity
JYK05_RS15510	COG3287	FIST C domain
JYK05_RS15525	COG5001	Diguanylate cyclase
JYK05_RS15535	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JYK05_RS15540	COG1228	amidohydrolase
JYK05_RS15545	COG2261	transglycosylase associated protein
JYK05_RS15555	COG3047	cAMP biosynthetic process
JYK05_RS15555	COG2885	chlorophyll binding
JYK05_RS15570	COG0583	DNA-binding transcription factor activity
JYK05_RS15575	COG0668	transmembrane transport
JYK05_RS15585	COG1446	asparaginase
JYK05_RS15590	COG4172	Belongs to the ABC transporter superfamily
JYK05_RS15595	COG0747	negative chemotaxis
JYK05_RS15600	COG0601	transmembrane transport
JYK05_RS15605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JYK05_RS15625	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JYK05_RS15630	COG1247	-acetyltransferase
JYK05_RS15635	COG2986	histidine ammonia-lyase
JYK05_RS15640	COG2188	Transcriptional regulator
JYK05_RS15670	COG0432	Pfam Uncharacterised protein family UPF0047
JYK05_RS15685	COG0330	HflC and HflK could
JYK05_RS15695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JYK05_RS15700	COG0436	Aminotransferase
JYK05_RS15725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JYK05_RS15770	COG2091	lysine biosynthetic process via aminoadipic acid
JYK05_RS15775	COG1451	nucleotide metabolic process
JYK05_RS15805	COG3128	pkhd-type hydroxylase
JYK05_RS15810	COG4774	siderophore transport
JYK05_RS15815	COG0004	ammonium transporteR
JYK05_RS15880	COG4977	sequence-specific DNA binding
JYK05_RS15905	COG1763	Mo-molybdopterin cofactor biosynthetic process
JYK05_RS15920	COG3121	Chaperone
JYK05_RS15945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JYK05_RS15950	COG2274	protein secretion by the type I secretion system
JYK05_RS15980	COG0745	RESPONSE REGULATOR receiver
JYK05_RS15990	COG0835	chemotaxis
JYK05_RS15990	COG0784	Response regulator, receiver
JYK05_RS15995	COG0517	IMP dehydrogenase activity
JYK05_RS16035	COG0443	Heat shock 70 kDa protein
JYK05_RS16045	COG1116	anion transmembrane transporter activity
JYK05_RS16045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JYK05_RS16050	COG3707	response regulator
JYK05_RS16065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JYK05_RS16070	COG2146	nitrite reductase [NAD(P)H] activity
JYK05_RS16070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JYK05_RS16075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JYK05_RS16080	COG0243	molybdopterin cofactor binding
JYK05_RS16085	COG0642	Histidine kinase
JYK05_RS16095	COG1538	Outer membrane efflux protein
JYK05_RS16125	COG1360	Flagellar Motor Protein
JYK05_RS16155	COG0477	Major facilitator Superfamily
JYK05_RS16160	COG0745	RESPONSE REGULATOR receiver
JYK05_RS16175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JYK05_RS16185	COG1522	sequence-specific DNA binding
JYK05_RS16205	COG2910	NAD(P)H-binding
JYK05_RS16225	COG0583	DNA-binding transcription factor activity
JYK05_RS16235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JYK05_RS16245	COG1538	Outer membrane efflux protein
JYK05_RS16380	COG1253	flavin adenine dinucleotide binding
JYK05_RS16395	COG4302	ethanolamine ammonia-lyase activity
JYK05_RS16405	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
JYK05_RS16410	COG0701	Predicted permease
JYK05_RS16420	COG1294	oxidase, subunit
JYK05_RS16425	COG1271	oxidase subunit
JYK05_RS16430	COG2321	neutral zinc metallopeptidase
JYK05_RS16440	COG3387	PFAM Glycoside hydrolase 15-related
JYK05_RS16470	COG0753	catalase activity
JYK05_RS16485	COG4214	carbohydrate transport
JYK05_RS16490	COG1129	ABC transporter
JYK05_RS16495	COG4213	ABC transporter substrate-binding protein
JYK05_RS16500	COG2115	Belongs to the xylose isomerase family
JYK05_RS16505	COG1609	Transcriptional regulator
JYK05_RS16505	COG2207	Transcriptional regulator
JYK05_RS16535	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JYK05_RS16550	COG0450	alkyl hydroperoxide reductase
JYK05_RS16555	COG0531	amino acid
JYK05_RS16570	COG1595	DNA-templated transcription, initiation
JYK05_RS16610	COG3604	Transcriptional regulator
JYK05_RS16625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JYK05_RS16630	COG1716	ATPase activity
JYK05_RS16635	COG1538	Outer membrane efflux protein
JYK05_RS16660	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JYK05_RS16720	COG0604	alcohol dehydrogenase
JYK05_RS16735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JYK05_RS16740	COG1063	alcohol dehydrogenase
JYK05_RS16755	COG3047	cAMP biosynthetic process
JYK05_RS16775	COG0492	ferredoxin-NADP+ reductase activity
JYK05_RS16785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JYK05_RS16805	COG2863	cytochrome
JYK05_RS16810	COG3604	Transcriptional regulator
JYK05_RS16825	COG4608	Belongs to the ABC transporter superfamily
JYK05_RS16835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JYK05_RS16840	COG0601	transmembrane transport
JYK05_RS16855	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS16865	COG2252	PERMEase
JYK05_RS16880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYK05_RS16885	COG0387	Pfam Sodium calcium exchanger
JYK05_RS16890	COG1764	response to oxidative stress
JYK05_RS16895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JYK05_RS16900	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JYK05_RS16930	COG2814	Major facilitator Superfamily
JYK05_RS16960	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JYK05_RS16965	COG0859	PFAM glycosyl transferase family 9
JYK05_RS16970	COG2192	nodulation
JYK05_RS16980	COG0859	PFAM glycosyl transferase family 9
JYK05_RS17000	COG5265	(ABC) transporter
JYK05_RS17005	COG0417	DNA replication proofreading
JYK05_RS17025	COG0668	transmembrane transport
JYK05_RS17040	COG0709	Synthesizes selenophosphate from selenide and ATP
JYK05_RS17090	COG2207	Transcriptional regulator
JYK05_RS17095	COG0667	Aldo Keto reductase
JYK05_RS17100	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS17115	COG0730	response to heat
JYK05_RS17125	COG0251	oxidation-reduction process
JYK05_RS17130	COG0583	DNA-binding transcription factor activity
JYK05_RS17140	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JYK05_RS17150	COG2366	antibiotic biosynthetic process
JYK05_RS17225	COG2186	Transcriptional regulator
JYK05_RS17230	COG3246	L-lysine catabolic process to acetate
JYK05_RS17280	COG2815	serine threonine protein kinase
JYK05_RS17280	COG0515	serine threonine protein kinase
JYK05_RS17300	COG1201	RNA secondary structure unwinding
JYK05_RS17310	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
JYK05_RS17315	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JYK05_RS17325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JYK05_RS17330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JYK05_RS17335	COG0583	DNA-binding transcription factor activity
JYK05_RS17360	COG1012	belongs to the aldehyde dehydrogenase family
JYK05_RS17370	COG2124	cytochrome p450
JYK05_RS17375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JYK05_RS17395	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JYK05_RS17400	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JYK05_RS17410	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS17415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JYK05_RS17440	COG0739	heme binding
JYK05_RS17455	COG0598	Magnesium transport protein CorA
JYK05_RS17460	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JYK05_RS17465	COG0561	phosphatase activity
JYK05_RS17475	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JYK05_RS17480	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JYK05_RS17510	COG2116	formate transmembrane transporter activity
JYK05_RS17515	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JYK05_RS17530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JYK05_RS17550	COG1879	ABC-type sugar transport system periplasmic component
JYK05_RS17560	COG4211	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS17565	COG1129	ABC transporter
JYK05_RS17570	COG3618	amidohydrolase
JYK05_RS17575	COG3254	rhamnose metabolic process
JYK05_RS17580	COG0583	DNA-binding transcription factor activity
JYK05_RS17585	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS17590	COG4948	Mandelate Racemase Muconate Lactonizing
JYK05_RS17595	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS17610	COG1278	Cold shock
JYK05_RS17675	COG0697	spore germination
JYK05_RS17715	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JYK05_RS17720	COG2085	NADP oxidoreductase coenzyme F420-dependent
JYK05_RS17730	COG3634	alkyl hydroperoxide reductase activity
JYK05_RS17735	COG2205	protein histidine kinase activity
JYK05_RS17740	COG4106	trans-aconitate 2-methyltransferase activity
JYK05_RS17795	COG2733	membrane
JYK05_RS17810	COG0596	Alpha beta hydrolase
JYK05_RS17870	COG0489	protein tyrosine kinase activity
JYK05_RS17880	COG4964	Belongs to the GSP D family
JYK05_RS17905	COG2094	Belongs to the DNA glycosylase MPG family
JYK05_RS17945	COG0302	gtp cyclohydrolase
JYK05_RS17950	COG1045	serine acetyltransferase
JYK05_RS17995	COG0477	Major facilitator Superfamily
JYK05_RS18000	COG0589	response to stress
JYK05_RS18005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JYK05_RS18010	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JYK05_RS18015	COG0438	transferase activity, transferring glycosyl groups
JYK05_RS18035	COG2894	cell division
JYK05_RS18040	COG1215	transferase activity, transferring glycosyl groups
JYK05_RS18045	COG1215	transferase activity, transferring glycosyl groups
JYK05_RS18050	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JYK05_RS18055	COG0457	Tetratricopeptide repeat
JYK05_RS18060	COG0431	NADPH-dependent FMN reductase
JYK05_RS18075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JYK05_RS18080	COG0583	DNA-binding transcription factor activity
JYK05_RS18085	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS18095	COG1192	Involved in chromosome partitioning
JYK05_RS18100	COG3300	MHYT domain
JYK05_RS18100	COG5001	Diguanylate cyclase
JYK05_RS18145	COG1116	anion transmembrane transporter activity
JYK05_RS18150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JYK05_RS18155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JYK05_RS18160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JYK05_RS18170	COG2205	protein histidine kinase activity
JYK05_RS18175	COG3447	MASE1 domain protein
JYK05_RS18175	COG5001	Diguanylate cyclase
JYK05_RS18175	COG5002	protein histidine kinase activity
JYK05_RS18205	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JYK05_RS18210	COG2271	Major facilitator Superfamily
JYK05_RS18220	COG2205	protein histidine kinase activity
JYK05_RS18220	COG0784	Response regulator, receiver
JYK05_RS18225	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS18235	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JYK05_RS18260	COG0542	response to heat
JYK05_RS18285	COG1566	PFAM secretion protein HlyD family protein
JYK05_RS18290	COG3706	GGDEF domain
JYK05_RS18315	COG0671	phosphoesterase, PA-phosphatase related
JYK05_RS18325	COG2345	Transcriptional regulator
JYK05_RS18345	COG3300	MHYT domain
JYK05_RS18345	COG5001	Diguanylate cyclase
JYK05_RS18350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JYK05_RS18350	COG1017	nitric oxide dioxygenase activity
JYK05_RS18360	COG2271	Major facilitator Superfamily
JYK05_RS18365	COG1609	Transcriptional regulator
JYK05_RS18385	COG2146	nitrite reductase [NAD(P)H] activity
JYK05_RS18390	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
JYK05_RS18395	COG4638	Rieske (2fe-2S)
JYK05_RS18410	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS18415	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS18420	COG1129	ABC transporter
JYK05_RS18425	COG1879	ABC-type sugar transport system periplasmic component
JYK05_RS18435	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JYK05_RS18440	COG1595	DNA-templated transcription, initiation
JYK05_RS18465	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS18520	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS18565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JYK05_RS18600	COG0586	Pfam SNARE associated Golgi protein
JYK05_RS18605	COG0586	Pfam SNARE associated Golgi protein
JYK05_RS18610	COG3276	selenocysteine insertion sequence binding
JYK05_RS18615	COG1921	L-seryl-tRNASec selenium transferase activity
JYK05_RS18625	COG2864	formate dehydrogenase
JYK05_RS18630	COG0437	4 iron, 4 sulfur cluster binding
JYK05_RS18640	COG1295	ribonuclease BN
JYK05_RS18645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JYK05_RS18660	COG2176	DNA-directed DNA polymerase activity
JYK05_RS18665	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS18670	COG0583	DNA-binding transcription factor activity
JYK05_RS18690	COG0667	Aldo Keto reductase
JYK05_RS18705	COG5487	UPF0391 membrane protein
JYK05_RS18720	COG0129	dihydroxy-acid dehydratase activity
JYK05_RS18725	COG1609	Transcriptional regulator
JYK05_RS18765	COG5002	protein histidine kinase activity
JYK05_RS18770	COG5002	protein histidine kinase activity
JYK05_RS18770	COG2198	Histidine kinase
JYK05_RS18770	COG0784	Response regulator, receiver
JYK05_RS18775	COG2172	sigma factor antagonist activity
JYK05_RS18785	COG1366	Belongs to the anti-sigma-factor antagonist family
JYK05_RS18790	COG1366	Belongs to the anti-sigma-factor antagonist family
JYK05_RS18795	COG2233	PERMEase
JYK05_RS18800	COG1073	alpha beta
JYK05_RS18815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JYK05_RS18830	COG2175	clavaminate synthase activity
JYK05_RS18835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JYK05_RS18845	COG0477	Major facilitator Superfamily
JYK05_RS18865	COG0583	DNA-binding transcription factor activity
JYK05_RS18885	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
JYK05_RS18925	COG2010	Cytochrome c
JYK05_RS18935	COG2154	pterin-4-alpha-carbinolamine dehydratase
JYK05_RS18945	COG0702	epimerase
JYK05_RS18955	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
JYK05_RS18970	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
JYK05_RS18985	COG3284	Transcriptional regulator
JYK05_RS19030	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JYK05_RS19040	COG1229	Formylmethanofuran dehydrogenase subunit A
JYK05_RS19045	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
JYK05_RS19055	COG3038	cytochrome b561
JYK05_RS19060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JYK05_RS19065	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
JYK05_RS19075	COG0535	radical SAM domain protein
JYK05_RS19125	COG0484	heat shock protein binding
JYK05_RS19140	COG0477	Major facilitator Superfamily
JYK05_RS19165	COG5001	Diguanylate cyclase
JYK05_RS19180	COG0765	amino acid transport
JYK05_RS19185	COG0765	amino acid transport
JYK05_RS19190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYK05_RS19210	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
JYK05_RS19215	COG1254	Belongs to the acylphosphatase family
JYK05_RS19230	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JYK05_RS19235	COG0784	Response regulator, receiver
JYK05_RS19235	COG2205	protein histidine kinase activity
JYK05_RS19240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JYK05_RS19265	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JYK05_RS19280	COG2879	small protein
JYK05_RS19285	COG1966	Carbon starvation protein
JYK05_RS19325	COG1657	PFAM Prenyltransferase squalene oxidase
JYK05_RS19330	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JYK05_RS19335	COG1562	ergosterol biosynthetic process
JYK05_RS19345	COG1776	CheC inhibitor of MCP methylation
JYK05_RS19345	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JYK05_RS19350	COG3437	response regulator, receiver
JYK05_RS19370	COG0679	Auxin Efflux Carrier
JYK05_RS19375	COG3040	lipid binding
JYK05_RS19385	COG3604	Transcriptional regulator
JYK05_RS19390	COG2610	gluconate transmembrane transporter activity
JYK05_RS19400	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS19405	COG0840	transmembrane signaling receptor activity
JYK05_RS19415	COG0628	permease
JYK05_RS19420	COG0625	glutathione transferase activity
JYK05_RS19425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JYK05_RS19425	COG1017	nitric oxide dioxygenase activity
JYK05_RS19435	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JYK05_RS19445	COG0655	NAD(P)H dehydrogenase (quinone) activity
JYK05_RS19455	COG1414	Transcriptional regulator
JYK05_RS19460	COG0477	Major facilitator Superfamily
JYK05_RS19465	COG0583	DNA-binding transcription factor activity
JYK05_RS19475	COG0642	Histidine kinase
JYK05_RS19485	COG4829	muconolactone delta-isomerase
JYK05_RS19490	COG4948	Mandelate Racemase Muconate Lactonizing
JYK05_RS19495	COG0583	DNA-binding transcription factor activity
JYK05_RS19520	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS19535	COG2353	YceI-like domain
JYK05_RS19540	COG1063	alcohol dehydrogenase
JYK05_RS19550	COG1396	sequence-specific DNA binding
JYK05_RS19580	COG1012	belongs to the aldehyde dehydrogenase family
JYK05_RS19590	COG0165	Argininosuccinate lyase
JYK05_RS19615	COG1137	ATPase activity
JYK05_RS19655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JYK05_RS19660	COG0251	oxidation-reduction process
JYK05_RS19665	COG3473	Maleate cis-trans isomerase
JYK05_RS19730	COG0028	Belongs to the TPP enzyme family
JYK05_RS19735	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JYK05_RS19745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JYK05_RS19750	COG4120	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS19760	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JYK05_RS19770	COG1012	belongs to the aldehyde dehydrogenase family
JYK05_RS19785	COG1309	transcriptional regulator
JYK05_RS19795	COG1131	(ABC) transporter
JYK05_RS19800	COG0842	Transport permease protein
JYK05_RS19815	COG2272	Belongs to the type-B carboxylesterase lipase family
JYK05_RS19845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JYK05_RS19855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JYK05_RS19860	COG1116	anion transmembrane transporter activity
JYK05_RS19865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JYK05_RS19880	COG0583	DNA-binding transcription factor activity
JYK05_RS19885	COG2271	Major facilitator Superfamily
JYK05_RS19910	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JYK05_RS19915	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JYK05_RS19920	COG2186	Transcriptional regulator
JYK05_RS19930	COG2271	Major facilitator Superfamily
JYK05_RS19970	COG0601	transmembrane transport
JYK05_RS19980	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JYK05_RS19985	COG0747	negative chemotaxis
JYK05_RS19995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYK05_RS20005	COG0765	amino acid transport
JYK05_RS20025	COG0640	Transcriptional regulator
JYK05_RS20030	COG1902	pentaerythritol trinitrate reductase activity
JYK05_RS20035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYK05_RS20040	COG0765	amino acid transport
JYK05_RS20045	COG0765	amino acid transport
JYK05_RS20060	COG0154	amidase activity
JYK05_RS20095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JYK05_RS20110	COG0840	transmembrane signaling receptor activity
JYK05_RS20115	COG2814	Major facilitator Superfamily
JYK05_RS20190	COG2271	Major facilitator Superfamily
JYK05_RS20200	COG1802	Transcriptional regulator
JYK05_RS20245	COG2814	Major facilitator Superfamily
JYK05_RS20265	COG3386	PFAM SMP-30 Gluconolaconase
JYK05_RS20270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYK05_RS20275	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JYK05_RS20280	COG1414	Transcriptional regulator
JYK05_RS20300	COG0477	Major facilitator Superfamily
JYK05_RS20305	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JYK05_RS20310	COG0583	DNA-binding transcription factor activity
JYK05_RS20315	COG1301	dicarboxylic acid transport
JYK05_RS20330	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JYK05_RS20340	COG1309	transcriptional regulator
JYK05_RS20350	COG3842	ATPase activity
JYK05_RS20370	COG0154	amidase activity
JYK05_RS20375	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS20400	COG1137	ATPase activity
JYK05_RS20405	COG4177	L-phenylalanine transmembrane transporter activity
JYK05_RS20420	COG1802	Transcriptional regulator
JYK05_RS20430	COG0559	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS20460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JYK05_RS20475	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS20480	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS20485	COG1129	ABC transporter
JYK05_RS20490	COG1879	ABC-type sugar transport system periplasmic component
JYK05_RS20495	COG3284	Transcriptional regulator
JYK05_RS20515	COG1012	belongs to the aldehyde dehydrogenase family
JYK05_RS20525	COG1953	Uracil, thiamine, allantoin
JYK05_RS20535	COG0493	'glutamate synthase
JYK05_RS20545	COG1309	transcriptional regulator
JYK05_RS20575	COG3842	ATPase activity
JYK05_RS20590	COG4770	biotin carboxylase activity
JYK05_RS20600	COG2207	Transcriptional regulator
JYK05_RS20625	COG2267	carboxylic ester hydrolase activity
JYK05_RS20630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JYK05_RS20635	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JYK05_RS20640	COG2080	2 iron, 2 sulfur cluster binding
JYK05_RS20660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JYK05_RS20680	COG3938	Belongs to the proline racemase family
JYK05_RS20685	COG0683	leucine binding
JYK05_RS20690	COG2376	Dihydroxyacetone kinase
JYK05_RS20705	COG0840	transmembrane signaling receptor activity
JYK05_RS20750	COG2072	flavoprotein involved in K transport
JYK05_RS20765	COG3842	ATPase activity
JYK05_RS20800	COG0300	oxidoreductase activity
JYK05_RS20805	COG2207	Transcriptional regulator
JYK05_RS20815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JYK05_RS20825	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JYK05_RS20830	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS20835	COG1129	ABC transporter
JYK05_RS20845	COG1879	ABC-type sugar transport system periplasmic component
JYK05_RS20850	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS20855	COG3958	Transketolase
JYK05_RS20860	COG3959	Transketolase, thiamine diphosphate binding domain
JYK05_RS20865	COG1349	DNA-binding transcription factor activity
JYK05_RS20870	COG1879	ABC-type sugar transport system periplasmic component
JYK05_RS20875	COG3386	PFAM SMP-30 Gluconolaconase
JYK05_RS20880	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS20885	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS20890	COG1129	ABC transporter
JYK05_RS20895	COG1879	ABC-type sugar transport system periplasmic component
JYK05_RS20910	COG0243	molybdopterin cofactor binding
JYK05_RS20920	COG1215	transferase activity, transferring glycosyl groups
JYK05_RS20930	COG0583	DNA-binding transcription factor activity
JYK05_RS20940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JYK05_RS20955	COG2814	Major facilitator Superfamily
JYK05_RS20960	COG2188	Transcriptional regulator
JYK05_RS20965	COG0546	phosphoglycolate phosphatase activity
JYK05_RS20985	COG0840	transmembrane signaling receptor activity
JYK05_RS20990	COG5002	protein histidine kinase activity
JYK05_RS21020	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JYK05_RS21035	COG4977	sequence-specific DNA binding
JYK05_RS21045	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS21050	COG2205	protein histidine kinase activity
JYK05_RS21055	COG0824	Thioesterase
JYK05_RS21055	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYK05_RS21060	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYK05_RS21065	COG3246	L-lysine catabolic process to acetate
JYK05_RS21080	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JYK05_RS21090	COG3119	arylsulfatase activity
JYK05_RS21095	COG0583	DNA-binding transcription factor activity
JYK05_RS21100	COG1309	transcriptional regulator
JYK05_RS21105	COG1012	belongs to the aldehyde dehydrogenase family
JYK05_RS21110	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JYK05_RS21125	COG3038	cytochrome b561
JYK05_RS21160	COG0028	Belongs to the TPP enzyme family
JYK05_RS21190	COG0243	molybdopterin cofactor binding
JYK05_RS21225	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS21230	COG3387	PFAM Glycoside hydrolase 15-related
JYK05_RS21235	COG2132	Multicopper oxidase
JYK05_RS21240	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS21245	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS21250	COG1129	ABC transporter
JYK05_RS21265	COG2267	carboxylic ester hydrolase activity
JYK05_RS21270	COG0179	Fumarylacetoacetate (FAA) hydrolase
JYK05_RS21285	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS21295	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JYK05_RS21330	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JYK05_RS21340	COG1858	cytochrome C peroxidase
JYK05_RS21350	COG3706	GGDEF domain
JYK05_RS21365	COG3321	synthase
JYK05_RS21365	COG0604	alcohol dehydrogenase
JYK05_RS21365	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS21370	COG0667	Aldo Keto reductase
JYK05_RS21375	COG0583	DNA-binding transcription factor activity
JYK05_RS21385	COG0753	catalase activity
JYK05_RS21395	COG3706	GGDEF domain
JYK05_RS21400	COG0583	DNA-binding transcription factor activity
JYK05_RS21410	COG0477	Major facilitator Superfamily
JYK05_RS21420	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYK05_RS21420	COG1024	Enoyl-CoA hydratase
JYK05_RS21455	COG0583	DNA-binding transcription factor activity
JYK05_RS21460	COG1012	belongs to the aldehyde dehydrogenase family
JYK05_RS21470	COG3706	GGDEF domain
JYK05_RS21475	COG2084	Dehydrogenase
JYK05_RS21485	COG2271	Major facilitator Superfamily
JYK05_RS21495	COG2721	sulfolactate sulfo-lyase activity
JYK05_RS21510	COG1764	response to oxidative stress
JYK05_RS21515	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS21525	COG0583	DNA-binding transcription factor activity
JYK05_RS21530	COG1846	Transcriptional regulator
JYK05_RS21535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JYK05_RS21545	COG1773	rubredoxin
JYK05_RS21580	COG0583	DNA-binding transcription factor activity
JYK05_RS21585	COG3511	phospholipase C
JYK05_RS21595	COG2323	membrane
JYK05_RS21600	COG2323	membrane
JYK05_RS21620	COG0784	Response regulator, receiver
JYK05_RS21620	COG4191	Histidine kinase
JYK05_RS21650	COG1278	Cold shock
JYK05_RS21660	COG5002	protein histidine kinase activity
JYK05_RS21660	COG5001	Diguanylate cyclase
JYK05_RS21670	COG3047	cAMP biosynthetic process
JYK05_RS21685	COG2267	carboxylic ester hydrolase activity
JYK05_RS21725	COG1285	pathogenesis
JYK05_RS21735	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS21765	COG0494	nUDIX hydrolase
JYK05_RS21785	COG3685	Protein conserved in bacteria
JYK05_RS21790	COG3546	catalase activity
JYK05_RS21795	COG2155	Conserved Protein
JYK05_RS21800	COG0688	phosphatidylethanolamine metabolic process
JYK05_RS21820	COG3685	Protein conserved in bacteria
JYK05_RS21875	COG1380	Effector of murein hydrolase LrgA
JYK05_RS21880	COG1346	cytolysis
JYK05_RS21890	COG1914	H( )-stimulated, divalent metal cation uptake system
JYK05_RS21920	COG0438	transferase activity, transferring glycosyl groups
JYK05_RS21925	COG0438	transferase activity, transferring glycosyl groups
JYK05_RS21930	COG0561	phosphatase activity
JYK05_RS21935	COG4993	Dehydrogenase
JYK05_RS21940	COG1295	ribonuclease BN
JYK05_RS21970	COG1192	Involved in chromosome partitioning
JYK05_RS21975	COG1475	DNA binding
JYK05_RS22000	COG0583	DNA-binding transcription factor activity
JYK05_RS22005	COG0673	inositol 2-dehydrogenase activity
JYK05_RS22015	COG4774	siderophore transport
JYK05_RS22025	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JYK05_RS22035	COG0137	argininosuccinate synthase activity
JYK05_RS22050	COG4589	Belongs to the CDS family
JYK05_RS22060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JYK05_RS22065	COG1216	Glycosyl transferase, family 2
JYK05_RS22075	COG4804	nuclease activity
JYK05_RS22095	COG0129	dihydroxy-acid dehydratase activity
JYK05_RS22100	COG1115	amino acid carrier protein
JYK05_RS22110	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS22115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYK05_RS22115	COG2205	protein histidine kinase activity
JYK05_RS22120	COG2203	Gaf domain
JYK05_RS22120	COG5001	Diguanylate cyclase
JYK05_RS22120	COG3706	GGDEF domain
JYK05_RS22120	COG4251	negative regulation of phosphorylation
JYK05_RS22160	COG0840	transmembrane signaling receptor activity
JYK05_RS22170	COG0745	RESPONSE REGULATOR receiver
JYK05_RS22205	COG2271	Major facilitator Superfamily
JYK05_RS22215	COG4948	Mandelate Racemase Muconate Lactonizing
JYK05_RS22225	COG2271	Major facilitator Superfamily
JYK05_RS22235	COG0583	DNA-binding transcription factor activity
JYK05_RS22240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JYK05_RS22260	COG3206	protein involved in exopolysaccharide biosynthesis
JYK05_RS22260	COG0489	protein tyrosine kinase activity
JYK05_RS22280	COG3206	protein involved in exopolysaccharide biosynthesis
JYK05_RS22280	COG0489	protein tyrosine kinase activity
JYK05_RS22305	COG0438	transferase activity, transferring glycosyl groups
JYK05_RS22335	COG2175	clavaminate synthase activity
JYK05_RS22360	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS22365	COG4948	Mandelate Racemase Muconate Lactonizing
JYK05_RS22375	COG1129	ABC transporter
JYK05_RS22380	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS22400	COG2009	succinate dehydrogenase
JYK05_RS22410	COG1053	succinate dehydrogenase
JYK05_RS22415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JYK05_RS22420	COG0583	DNA-binding transcription factor activity
JYK05_RS22430	COG3246	L-lysine catabolic process to acetate
JYK05_RS22440	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS22445	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS22470	COG2205	protein histidine kinase activity
JYK05_RS22490	COG1764	response to oxidative stress
JYK05_RS22500	COG0477	Major facilitator Superfamily
JYK05_RS22530	COG0659	secondary active sulfate transmembrane transporter activity
JYK05_RS22555	COG2201	protein-glutamate methylesterase activity
JYK05_RS22565	COG4206	TonB-dependent receptor
JYK05_RS22580	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JYK05_RS22610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JYK05_RS22655	COG0154	amidase activity
JYK05_RS22680	COG4638	Rieske (2fe-2S)
JYK05_RS22720	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JYK05_RS22740	COG3284	Transcriptional regulator
JYK05_RS22745	COG3199	ATP-NAD kinase
JYK05_RS22750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JYK05_RS22755	COG0022	dehydrogenase e1 component
JYK05_RS22760	COG0508	dehydrogenase complex catalyzes the overall conversion of
JYK05_RS22760	COG0596	Alpha beta hydrolase
JYK05_RS22770	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JYK05_RS22810	COG5001	Diguanylate cyclase
JYK05_RS22810	COG3447	MASE1 domain protein
JYK05_RS22810	COG5002	protein histidine kinase activity
JYK05_RS22815	COG5001	Diguanylate cyclase
JYK05_RS22860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JYK05_RS22865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JYK05_RS22875	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS22885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JYK05_RS22895	COG1129	ABC transporter
JYK05_RS22900	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS22905	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYK05_RS22910	COG3386	PFAM SMP-30 Gluconolaconase
JYK05_RS22915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JYK05_RS22920	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS22930	COG1129	ABC transporter
JYK05_RS22940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JYK05_RS22945	COG2188	Transcriptional regulator
JYK05_RS22950	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JYK05_RS22955	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JYK05_RS22960	COG0235	Class ii aldolase
JYK05_RS22965	COG1879	ABC-type sugar transport system periplasmic component
JYK05_RS22970	COG1129	ABC transporter
JYK05_RS22975	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS22980	COG2376	Dihydroxyacetone kinase
JYK05_RS22985	COG1461	Dihydroxyacetone kinase
JYK05_RS22995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JYK05_RS23000	COG0346	lactoylglutathione lyase activity
JYK05_RS23010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JYK05_RS23015	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JYK05_RS23025	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JYK05_RS23035	COG0427	acetyl-CoA hydrolase
JYK05_RS23045	COG0583	DNA-binding transcription factor activity
JYK05_RS23070	COG0492	ferredoxin-NADP+ reductase activity
JYK05_RS23075	COG2271	Major facilitator Superfamily
JYK05_RS23080	COG0583	DNA-binding transcription factor activity
JYK05_RS23100	COG2205	protein histidine kinase activity
JYK05_RS23130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JYK05_RS23140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYK05_RS23140	COG2205	protein histidine kinase activity
JYK05_RS23175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JYK05_RS23180	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JYK05_RS23185	COG4521	taurine ABC transporter
JYK05_RS23200	COG2205	protein histidine kinase activity
JYK05_RS23210	COG2197	response regulator
JYK05_RS23220	COG0515	serine threonine protein kinase
JYK05_RS23220	COG3064	Membrane
JYK05_RS23220	COG4991	sh3 domain protein
JYK05_RS23375	COG2197	response regulator
JYK05_RS23420	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
JYK05_RS23445	COG1012	belongs to the aldehyde dehydrogenase family
JYK05_RS23460	COG0583	DNA-binding transcription factor activity
JYK05_RS23465	COG2814	Major facilitator Superfamily
JYK05_RS23475	COG3842	ATPase activity
JYK05_RS23480	COG3842	ATPase activity
JYK05_RS23510	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS23515	COG0567	Dehydrogenase, E1 component
JYK05_RS23530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JYK05_RS23535	COG2814	Major facilitator Superfamily
JYK05_RS23565	COG1414	Transcriptional regulator
JYK05_RS23590	COG1414	Transcriptional regulator
JYK05_RS23595	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS23615	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JYK05_RS23620	COG3206	protein involved in exopolysaccharide biosynthesis
JYK05_RS23620	COG0489	protein tyrosine kinase activity
JYK05_RS23635	COG4804	nuclease activity
JYK05_RS23665	COG1183	phosphatidylcholine synthase activity
JYK05_RS23690	COG2197	response regulator
JYK05_RS23705	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
JYK05_RS23735	COG2197	response regulator
JYK05_RS23740	COG2205	protein histidine kinase activity
JYK05_RS23740	COG0784	Response regulator, receiver
JYK05_RS23750	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JYK05_RS23805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JYK05_RS23810	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JYK05_RS23815	COG3395	kinase activity
JYK05_RS23825	COG1349	DNA-binding transcription factor activity
JYK05_RS23830	COG0784	Response regulator, receiver
JYK05_RS23830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYK05_RS23830	COG2205	protein histidine kinase activity
JYK05_RS23830	COG2198	Histidine kinase
JYK05_RS23855	COG0235	Class ii aldolase
JYK05_RS23860	COG1942	4-Oxalocrotonate Tautomerase
JYK05_RS23865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JYK05_RS23870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JYK05_RS23875	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JYK05_RS23880	COG2080	2 iron, 2 sulfur cluster binding
JYK05_RS23895	COG0583	DNA-binding transcription factor activity
JYK05_RS23900	COG1473	amidohydrolase
JYK05_RS23925	COG2223	nitrite transmembrane transporter activity
JYK05_RS23930	COG1024	Enoyl-CoA hydratase
JYK05_RS23935	COG0318	PFAM AMP-dependent synthetase and ligase
JYK05_RS23940	COG0625	glutathione transferase activity
JYK05_RS23950	COG0683	leucine binding
JYK05_RS23965	COG1129	ABC transporter
JYK05_RS24000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JYK05_RS24005	COG5001	Diguanylate cyclase
JYK05_RS24010	COG4191	Histidine kinase
JYK05_RS24010	COG0784	Response regulator, receiver
JYK05_RS24025	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS24030	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS24035	COG1129	ABC transporter
JYK05_RS24040	COG1879	ABC-type sugar transport system periplasmic component
JYK05_RS24045	COG1609	Transcriptional regulator
JYK05_RS24085	COG1573	uracil-dna glycosylase
JYK05_RS24090	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS24125	COG3842	ATPase activity
JYK05_RS24135	COG1175	transmembrane transport
JYK05_RS24150	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS24155	COG1063	alcohol dehydrogenase
JYK05_RS24160	COG1063	alcohol dehydrogenase
JYK05_RS24200	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JYK05_RS24200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JYK05_RS24205	COG3132	Protein of unknown function, DUF480
JYK05_RS24210	COG2308	Evidence 4 Homologs of previously reported genes of
JYK05_RS24235	COG1305	Transglutaminase-like
JYK05_RS24255	COG0840	transmembrane signaling receptor activity
JYK05_RS24270	COG0028	Belongs to the TPP enzyme family
JYK05_RS24280	COG4191	Histidine kinase
JYK05_RS24280	COG0784	Response regulator, receiver
JYK05_RS24285	COG0235	Class ii aldolase
JYK05_RS24290	COG3395	kinase activity
JYK05_RS24320	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS24325	COG0583	DNA-binding transcription factor activity
JYK05_RS24365	COG0784	Response regulator, receiver
JYK05_RS24420	COG1960	acyl-CoA dehydrogenase activity
JYK05_RS24425	COG3119	arylsulfatase activity
JYK05_RS24430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JYK05_RS24440	COG1022	Amp-dependent synthetase and ligase
JYK05_RS24465	COG0628	permease
JYK05_RS24475	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JYK05_RS24550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYK05_RS24555	COG2985	domain, Protein
JYK05_RS24555	COG0569	domain protein
JYK05_RS24565	COG0058	SHG alpha-glucan phosphorylase activity
JYK05_RS24585	COG4191	Histidine kinase
JYK05_RS24585	COG0784	Response regulator, receiver
JYK05_RS24595	COG1695	Transcriptional regulator
JYK05_RS24600	COG2375	cellular response to nickel ion
JYK05_RS24605	COG0583	DNA-binding transcription factor activity
JYK05_RS24620	COG1349	DNA-binding transcription factor activity
JYK05_RS24630	COG1129	ABC transporter
JYK05_RS24640	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS24655	COG1012	belongs to the aldehyde dehydrogenase family
JYK05_RS24660	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JYK05_RS24680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JYK05_RS24690	COG0747	negative chemotaxis
JYK05_RS24695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JYK05_RS24715	COG3829	transcription factor binding
JYK05_RS24720	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JYK05_RS24740	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS24750	COG0477	Major facilitator Superfamily
JYK05_RS24755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JYK05_RS24785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JYK05_RS24795	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JYK05_RS24815	COG4772	TonB-dependent receptor
JYK05_RS24835	COG0577	efflux transmembrane transporter activity
JYK05_RS24835	COG1136	(ABC) transporter
JYK05_RS24840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JYK05_RS24855	COG5001	Diguanylate cyclase
JYK05_RS24855	COG3706	GGDEF domain
JYK05_RS24855	COG2203	Gaf domain
JYK05_RS24855	COG4251	negative regulation of phosphorylation
JYK05_RS24875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JYK05_RS24885	COG2271	Major facilitator Superfamily
JYK05_RS24890	COG0277	FAD linked oxidase domain protein
JYK05_RS24890	COG0247	lactate metabolic process
JYK05_RS24900	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JYK05_RS24905	COG1802	Transcriptional regulator
JYK05_RS24930	COG0667	Aldo Keto reductase
JYK05_RS24945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JYK05_RS24950	COG1609	Transcriptional regulator
JYK05_RS24955	COG2271	Major facilitator Superfamily
JYK05_RS24960	COG0840	transmembrane signaling receptor activity
JYK05_RS24965	COG0463	Glycosyl transferase, family 2
JYK05_RS24975	COG0745	RESPONSE REGULATOR receiver
JYK05_RS24980	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JYK05_RS24990	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS24995	COG1278	Cold shock
JYK05_RS25005	COG0730	response to heat
JYK05_RS25020	COG2841	Protein conserved in bacteria
JYK05_RS25040	COG2159	amidohydrolase
JYK05_RS25045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JYK05_RS25055	COG2267	carboxylic ester hydrolase activity
JYK05_RS25070	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
JYK05_RS25085	COG5002	protein histidine kinase activity
JYK05_RS25125	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS25130	COG2271	Major facilitator Superfamily
JYK05_RS25135	COG3959	Transketolase, thiamine diphosphate binding domain
JYK05_RS25140	COG3958	Transketolase
JYK05_RS25150	COG2885	chlorophyll binding
JYK05_RS25215	COG1566	PFAM secretion protein HlyD family protein
JYK05_RS25235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JYK05_RS25240	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
JYK05_RS25245	COG1595	DNA-templated transcription, initiation
JYK05_RS25250	COG4944	Protein of unknown function (DUF1109)
JYK05_RS25260	COG0625	glutathione transferase activity
JYK05_RS25270	COG2721	sulfolactate sulfo-lyase activity
JYK05_RS25315	COG0596	Alpha beta hydrolase
JYK05_RS25375	COG1560	Kdo2-lipid A biosynthetic process
JYK05_RS25375	COG4783	chaperone-mediated protein folding
JYK05_RS25400	COG0438	transferase activity, transferring glycosyl groups
JYK05_RS25405	COG0457	Tetratricopeptide repeat
JYK05_RS25425	COG2159	amidohydrolase
JYK05_RS25435	COG3384	dioxygenase
JYK05_RS25455	COG3300	MHYT domain
JYK05_RS25455	COG5001	Diguanylate cyclase
JYK05_RS25480	COG3713	MltA-interacting MipA family protein
JYK05_RS25485	COG2814	Major facilitator Superfamily
JYK05_RS25525	COG2824	Alkylphosphonate utilization operon protein PhnA
JYK05_RS25530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JYK05_RS25535	COG1116	anion transmembrane transporter activity
JYK05_RS25540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JYK05_RS25560	COG2070	2-Nitropropane dioxygenase
JYK05_RS25570	COG0583	DNA-binding transcription factor activity
JYK05_RS25580	COG3588	fructose-bisphosphate aldolase
JYK05_RS25590	COG0596	Alpha beta hydrolase
JYK05_RS25595	COG0583	DNA-binding transcription factor activity
JYK05_RS25600	COG1562	ergosterol biosynthetic process
JYK05_RS25630	COG2816	NAD+ diphosphatase activity
JYK05_RS25635	COG1609	Transcriptional regulator
JYK05_RS25645	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JYK05_RS25680	COG1064	alcohol dehydrogenase
JYK05_RS25725	COG2070	2-Nitropropane dioxygenase
JYK05_RS25760	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JYK05_RS25770	COG2271	Major facilitator Superfamily
JYK05_RS25775	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS25780	COG1414	Transcriptional regulator
JYK05_RS25825	COG2814	Major facilitator Superfamily
JYK05_RS25835	COG1414	Transcriptional regulator
JYK05_RS25845	COG1879	ABC-type sugar transport system periplasmic component
JYK05_RS25850	COG1956	GAF domain-containing protein
JYK05_RS25860	COG1129	ABC transporter
JYK05_RS25865	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK05_RS25875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JYK05_RS25900	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS25905	COG0183	Belongs to the thiolase family
JYK05_RS25920	COG1914	H( )-stimulated, divalent metal cation uptake system
JYK05_RS25930	COG1192	Involved in chromosome partitioning
JYK05_RS25945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JYK05_RS25955	COG0625	glutathione transferase activity
JYK05_RS25965	COG1028	Short-chain dehydrogenase reductase Sdr
JYK05_RS25975	COG0095	Lipoate-protein ligase
JYK05_RS25995	COG0494	nUDIX hydrolase
JYK05_RS26015	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JYK05_RS26050	COG4251	negative regulation of phosphorylation
JYK05_RS26050	COG3706	GGDEF domain
JYK05_RS26050	COG2203	Gaf domain
JYK05_RS26050	COG5001	Diguanylate cyclase
JYK05_RS26080	COG0514	ATP-dependent DNA helicase (RecQ)
JYK05_RS26095	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JYK05_RS26100	COG3546	catalase activity
JYK05_RS26125	COG1902	pentaerythritol trinitrate reductase activity
JYK05_RS26135	COG1136	(ABC) transporter
JYK05_RS26150	COG2391	methyltransferase activity
JYK05_RS26155	COG0778	Nitroreductase
JYK05_RS26170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JYK05_RS26175	COG1045	serine acetyltransferase
JYK05_RS26210	COG0438	transferase activity, transferring glycosyl groups
JYK05_RS26220	COG0438	transferase activity, transferring glycosyl groups