locus-tag	class	description
CA733_RS00015	COG2831	hemolysin activation secretion protein
CA733_RS00035	COG0584	glycerophosphoryl diester phosphodiesterase
CA733_RS00050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CA733_RS00065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CA733_RS00070	COG1446	asparaginase
CA733_RS00085	COG1085	galactose-1-phosphate uridylyltransferase
CA733_RS00100	COG2304	oxidoreductase activity
CA733_RS00110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CA733_RS00115	COG4191	Histidine kinase
CA733_RS00120	COG2197	response regulator
CA733_RS00200	COG0667	Aldo Keto reductase
CA733_RS00220	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CA733_RS00230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CA733_RS00245	COG0515	serine threonine protein kinase
CA733_RS00250	COG0515	serine threonine protein kinase
CA733_RS00260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CA733_RS00270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CA733_RS00310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CA733_RS00325	COG3228	Belongs to the MtfA family
CA733_RS00340	COG2815	serine threonine protein kinase
CA733_RS00340	COG0515	serine threonine protein kinase
CA733_RS00345	COG1120	ATPase activity
CA733_RS00350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CA733_RS00370	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CA733_RS00425	COG1408	metallophosphoesterase
CA733_RS00430	COG4106	trans-aconitate 2-methyltransferase activity
CA733_RS00460	COG0475	glutathione-regulated potassium exporter activity
CA733_RS00465	COG0475	glutathione-regulated potassium exporter activity
CA733_RS00490	COG4208	sulfate ABC transporter
CA733_RS00495	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CA733_RS00500	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CA733_RS00505	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CA733_RS00515	COG0352	thiamine-phosphate diphosphorylase activity
CA733_RS00545	COG2211	Major facilitator Superfamily
CA733_RS00550	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CA733_RS00575	COG1657	PFAM Prenyltransferase squalene oxidase
CA733_RS00580	COG0463	Glycosyl transferase, family 2
CA733_RS00605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA733_RS00630	COG3335	DDE superfamily endonuclease
CA733_RS00640	COG0539	negative regulation of cytoplasmic translation
CA733_RS00660	COG0747	negative chemotaxis
CA733_RS00665	COG0601	transmembrane transport
CA733_RS00715	COG0784	Response regulator, receiver
CA733_RS00720	COG2203	Gaf domain
CA733_RS00720	COG5001	Diguanylate cyclase
CA733_RS00720	COG4251	negative regulation of phosphorylation
CA733_RS00720	COG3706	GGDEF domain
CA733_RS00770	COG0745	RESPONSE REGULATOR receiver
CA733_RS00785	COG3659	wide pore channel activity
CA733_RS00790	COG0140	phosphoribosyl-ATP diphosphatase activity
CA733_RS00790	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CA733_RS00800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CA733_RS00805	COG0515	serine threonine protein kinase
CA733_RS00805	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS00815	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CA733_RS00820	COG0644	oxidoreductase
CA733_RS00830	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CA733_RS00835	COG2205	protein histidine kinase activity
CA733_RS00840	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CA733_RS00845	COG0071	Belongs to the small heat shock protein (HSP20) family
CA733_RS00855	COG0531	amino acid
CA733_RS00860	COG2261	transglycosylase associated protein
CA733_RS00865	COG3546	catalase activity
CA733_RS00880	COG2988	succinylglutamate desuccinylase activity
CA733_RS00885	COG0583	DNA-binding transcription factor activity
CA733_RS00895	COG0640	Transcriptional regulator
CA733_RS00900	COG3118	belongs to the thioredoxin family
CA733_RS00905	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS00910	COG1902	pentaerythritol trinitrate reductase activity
CA733_RS00930	COG2226	methyltransferase
CA733_RS00935	COG0625	glutathione transferase activity
CA733_RS00945	COG3335	DDE superfamily endonuclease
CA733_RS00955	COG1649	PFAM Uncharacterised BCR, COG1649
CA733_RS00975	COG1196	nuclear chromosome segregation
CA733_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CA733_RS01005	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CA733_RS01005	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CA733_RS01010	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CA733_RS01015	COG2066	Belongs to the glutaminase family
CA733_RS01045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA733_RS01095	COG1902	pentaerythritol trinitrate reductase activity
CA733_RS01105	COG0745	RESPONSE REGULATOR receiver
CA733_RS01130	COG0045	succinate-CoA ligase (ADP-forming) activity
CA733_RS01160	COG0438	transferase activity, transferring glycosyl groups
CA733_RS01175	COG0438	transferase activity, transferring glycosyl groups
CA733_RS01185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CA733_RS01220	COG0110	maltose O-acetyltransferase activity
CA733_RS01230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CA733_RS01240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA733_RS01260	COG2205	protein histidine kinase activity
CA733_RS01260	COG0784	Response regulator, receiver
CA733_RS01265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CA733_RS01295	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CA733_RS01300	COG0714	Associated with various cellular activities
CA733_RS01335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CA733_RS01345	COG0497	DNA recombination
CA733_RS01350	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CA733_RS01395	COG0123	including yeast histone deacetylase and acetoin utilization protein
CA733_RS01405	COG3266	domain, Protein
CA733_RS01405	COG0515	serine threonine protein kinase
CA733_RS01415	COG4932	domain protein
CA733_RS01420	COG2885	chlorophyll binding
CA733_RS01440	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CA733_RS01470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CA733_RS01480	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA733_RS01520	COG0596	Alpha beta hydrolase
CA733_RS01530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CA733_RS01535	COG1361	Conserved repeat domain
CA733_RS01550	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CA733_RS01555	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CA733_RS01560	COG0085	RNA polymerase activity
CA733_RS01565	COG0084	hydrolase, TatD family'
CA733_RS01570	COG0268	Binds directly to 16S ribosomal RNA
CA733_RS01575	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CA733_RS01595	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CA733_RS01630	COG0612	Peptidase, M16
CA733_RS01635	COG3001	Fructosamine kinase
CA733_RS01660	COG0438	transferase activity, transferring glycosyl groups
CA733_RS01665	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CA733_RS01675	COG0401	homolog of Blt101
CA733_RS01680	COG0023	Translation Initiation Factor
CA733_RS01685	COG0133	tryptophan synthase activity
CA733_RS01690	COG2205	protein histidine kinase activity
CA733_RS01690	COG0784	Response regulator, receiver
CA733_RS01745	COG0489	protein tyrosine kinase activity
CA733_RS01770	COG0110	maltose O-acetyltransferase activity
CA733_RS01775	COG1215	transferase activity, transferring glycosyl groups
CA733_RS01800	COG0438	transferase activity, transferring glycosyl groups
CA733_RS01805	COG0463	Glycosyl transferase, family 2
CA733_RS01825	COG1216	Glycosyl transferase, family 2
CA733_RS01825	COG0463	Glycosyl transferase, family 2
CA733_RS01865	COG0438	transferase activity, transferring glycosyl groups
CA733_RS01875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CA733_RS01890	COG0110	maltose O-acetyltransferase activity
CA733_RS01905	COG2119	membrane
CA733_RS01920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CA733_RS01920	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CA733_RS01930	COG0840	transmembrane signaling receptor activity
CA733_RS01930	COG2203	Gaf domain
CA733_RS01935	COG0531	amino acid
CA733_RS01950	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CA733_RS01955	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CA733_RS01975	COG3631	Ketosteroid isomerase-related protein
CA733_RS02020	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CA733_RS02025	COG0088	Forms part of the polypeptide exit tunnel
CA733_RS02030	COG0089	rRNA binding
CA733_RS02035	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CA733_RS02040	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CA733_RS02045	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CA733_RS02050	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CA733_RS02060	COG0255	Belongs to the universal ribosomal protein uL29 family
CA733_RS02065	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CA733_RS02070	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CA733_RS02075	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CA733_RS02080	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CA733_RS02085	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CA733_RS02090	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CA733_RS02095	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CA733_RS02100	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CA733_RS02105	COG0200	Binds to the 23S rRNA
CA733_RS02110	COG0201	protein transport
CA733_RS02115	COG0563	adenylate kinase activity
CA733_RS02120	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CA733_RS02125	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CA733_RS02130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CA733_RS02135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CA733_RS02140	COG0202	RNA polymerase activity
CA733_RS02145	COG0203	ribosomal protein L17
CA733_RS02150	COG0101	tRNA pseudouridine synthase activity
CA733_RS02160	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CA733_RS02165	COG0254	rRNA binding
CA733_RS02170	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CA733_RS02185	COG0488	(ABC) transporter
CA733_RS02190	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CA733_RS02240	COG0438	transferase activity, transferring glycosyl groups
CA733_RS02250	COG1381	Involved in DNA repair and RecF pathway recombination
CA733_RS02255	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CA733_RS02285	COG0799	negative regulation of ribosome biogenesis
CA733_RS02290	COG0297	glycogen (starch) synthase activity
CA733_RS02295	COG0583	DNA-binding transcription factor activity
CA733_RS02300	COG1126	abc transporter atp-binding protein
CA733_RS02305	COG0765	amino acid transport
CA733_RS02310	COG4597	amino acid ABC transporter
CA733_RS02315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA733_RS02330	COG0602	queuosine metabolic process
CA733_RS02335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CA733_RS02360	COG0436	Aminotransferase
CA733_RS02375	COG1136	(ABC) transporter
CA733_RS02380	COG4591	ABC-type transport system involved in lipoprotein release permease component
CA733_RS02390	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CA733_RS02390	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CA733_RS02400	COG0625	glutathione transferase activity
CA733_RS02405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CA733_RS02410	COG1121	(ABC) transporter
CA733_RS02435	COG1090	epimerase
CA733_RS02445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CA733_RS02450	COG0501	Belongs to the peptidase M48B family
CA733_RS02465	COG1372	Participates in initiation and elongation during chromosome replication
CA733_RS02465	COG0305	Participates in initiation and elongation during chromosome replication
CA733_RS02470	COG0359	binds to the 23S rRNA
CA733_RS02480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CA733_RS02505	COG1132	(ABC) transporter
CA733_RS02540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CA733_RS02570	COG1515	deoxyribonuclease V activity
CA733_RS02575	COG0406	alpha-ribazole phosphatase activity
CA733_RS02580	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CA733_RS02595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CA733_RS02600	COG3852	Histidine kinase
CA733_RS02625	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CA733_RS02635	COG0501	Belongs to the peptidase M48B family
CA733_RS02640	COG1704	LemA family
CA733_RS02675	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CA733_RS02680	COG2124	cytochrome p450
CA733_RS02715	COG0793	Belongs to the peptidase S41A family
CA733_RS02720	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CA733_RS02725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CA733_RS02740	COG0438	transferase activity, transferring glycosyl groups
CA733_RS02755	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CA733_RS02760	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CA733_RS02765	COG1959	2 iron, 2 sulfur cluster binding
CA733_RS02775	COG0038	chloride channel
CA733_RS02795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CA733_RS02800	COG1770	oligopeptidase
CA733_RS02810	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CA733_RS02815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CA733_RS02815	COG3320	Male sterility
CA733_RS02820	COG1032	radical SAM domain protein
CA733_RS02845	COG0095	Lipoate-protein ligase
CA733_RS02880	COG1127	ABC transporter
CA733_RS02890	COG0515	serine threonine protein kinase
CA733_RS02890	COG3266	domain, Protein
CA733_RS02920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CA733_RS02925	COG1361	Conserved repeat domain
CA733_RS02935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CA733_RS02945	COG1012	belongs to the aldehyde dehydrogenase family
CA733_RS02985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA733_RS02990	COG0431	NADPH-dependent FMN reductase
CA733_RS03000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CA733_RS03005	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CA733_RS03010	COG1045	serine acetyltransferase
CA733_RS03015	COG1959	2 iron, 2 sulfur cluster binding
CA733_RS03020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CA733_RS03050	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CA733_RS03145	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CA733_RS03155	COG0739	heme binding
CA733_RS03195	COG2080	2 iron, 2 sulfur cluster binding
CA733_RS03195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CA733_RS03220	COG3845	ABC transporter
CA733_RS03225	COG0542	response to heat
CA733_RS03230	COG0456	acetyltransferase
CA733_RS03235	COG0019	diaminopimelate decarboxylase activity
CA733_RS03240	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CA733_RS03245	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CA733_RS03255	COG0484	heat shock protein binding
CA733_RS03270	COG0589	response to stress
CA733_RS03275	COG0574	Belongs to the PEP-utilizing enzyme family
CA733_RS03275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CA733_RS03285	COG2326	polyphosphate kinase activity
CA733_RS03300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CA733_RS03325	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CA733_RS03335	COG1943	Transposase
CA733_RS03340	COG1222	aaa ATPase
CA733_RS03350	COG0515	serine threonine protein kinase
CA733_RS03360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CA733_RS03380	COG0312	modulator of DNA gyrase
CA733_RS03405	COG0668	transmembrane transport
CA733_RS03440	COG0625	glutathione transferase activity
CA733_RS03450	COG1125	glycine betaine transport
CA733_RS03450	COG0517	IMP dehydrogenase activity
CA733_RS03475	COG0314	molybdopterin synthase activity
CA733_RS03490	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CA733_RS03505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CA733_RS03510	COG0529	Catalyzes the synthesis of activated sulfate
CA733_RS03545	COG3548	integral membrane protein
CA733_RS03560	COG1136	(ABC) transporter
CA733_RS03570	COG0501	Belongs to the peptidase M48B family
CA733_RS03585	COG0793	Belongs to the peptidase S41A family
CA733_RS03620	COG0010	Belongs to the arginase family
CA733_RS03650	COG0438	transferase activity, transferring glycosyl groups
CA733_RS03655	COG1672	PFAM Archaeal ATPase
CA733_RS03655	COG2319	Wd-40 repeat
CA733_RS03720	COG0515	serine threonine protein kinase
CA733_RS03720	COG3266	domain, Protein
CA733_RS03730	COG3266	domain, Protein
CA733_RS03730	COG0515	serine threonine protein kinase
CA733_RS03795	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CA733_RS03800	COG0066	3-isopropylmalate dehydratase activity
CA733_RS03825	COG1752	Esterase of the alpha-beta hydrolase superfamily
CA733_RS03825	COG1752	Esterase of the alpha-beta hydrolase superfamily
CA733_RS03885	COG1845	cytochrome c oxidase, subunit III
CA733_RS03900	COG0745	RESPONSE REGULATOR receiver
CA733_RS03965	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
CA733_RS03990	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CA733_RS04000	COG0625	glutathione transferase activity
CA733_RS04030	COG0709	Synthesizes selenophosphate from selenide and ATP
CA733_RS04045	COG0515	serine threonine protein kinase
CA733_RS04045	COG3266	domain, Protein
CA733_RS04055	COG1473	amidohydrolase
CA733_RS04075	COG5592	hemerythrin HHE cation binding domain
CA733_RS04090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA733_RS04100	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CA733_RS04140	COG0752	glycyl-tRNA synthetase alpha subunit
CA733_RS04155	COG0745	RESPONSE REGULATOR receiver
CA733_RS04160	COG5002	protein histidine kinase activity
CA733_RS04165	COG5002	protein histidine kinase activity
CA733_RS04175	COG5000	phosphorelay sensor kinase activity
CA733_RS04175	COG5002	protein histidine kinase activity
CA733_RS04180	COG0745	RESPONSE REGULATOR receiver
CA733_RS04235	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CA733_RS04255	COG1175	transmembrane transport
CA733_RS04260	COG0004	ammonium transporteR
CA733_RS04265	COG1742	UPF0060 membrane protein
CA733_RS04270	COG0004	ammonium transporteR
CA733_RS04275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CA733_RS04280	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CA733_RS04310	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CA733_RS04320	COG2226	methyltransferase
CA733_RS04330	COG0693	protein deglycase activity
CA733_RS04335	COG2909	trisaccharide binding
CA733_RS04355	COG0357	Ribosomal RNA small subunit methyltransferase G
CA733_RS04360	COG1122	ATPase activity
CA733_RS04400	COG0784	Response regulator, receiver
CA733_RS04400	COG2205	protein histidine kinase activity
CA733_RS04420	COG0129	dihydroxy-acid dehydratase activity
CA733_RS04440	COG1136	(ABC) transporter
CA733_RS04455	COG0546	phosphoglycolate phosphatase activity
CA733_RS04460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CA733_RS04485	COG2197	response regulator
CA733_RS04495	COG2884	Cell division ATP-binding protein ftsE
CA733_RS04505	COG2198	Histidine kinase
CA733_RS04505	COG5002	protein histidine kinase activity
CA733_RS04505	COG0784	Response regulator, receiver
CA733_RS04530	COG3593	DNA synthesis involved in DNA repair
CA733_RS04540	COG2329	Antibiotic biosynthesis monooxygenase
CA733_RS04570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CA733_RS04575	COG1881	PFAM PEBP family protein
CA733_RS04655	COG2390	Transcriptional regulator
CA733_RS04665	COG1653	transport
CA733_RS04670	COG1175	transmembrane transport
CA733_RS04675	COG0395	ABC-type sugar transport system, permease component
CA733_RS04750	COG0837	glucose binding
CA733_RS04780	COG2124	cytochrome p450
CA733_RS04785	COG2130	NADP-dependent
CA733_RS04815	COG2084	Dehydrogenase
CA733_RS04835	COG2203	Gaf domain
CA733_RS04840	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CA733_RS04870	COG0596	Alpha beta hydrolase
CA733_RS04875	COG1937	Protein conserved in bacteria
CA733_RS04880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA733_RS04885	COG2161	toxin-antitoxin pair type II binding
CA733_RS04905	COG1012	belongs to the aldehyde dehydrogenase family
CA733_RS04930	COG2205	protein histidine kinase activity
CA733_RS04940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CA733_RS04955	COG4106	trans-aconitate 2-methyltransferase activity
CA733_RS04980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CA733_RS05015	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS05025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CA733_RS05035	COG0745	RESPONSE REGULATOR receiver
CA733_RS05040	COG0515	serine threonine protein kinase
CA733_RS05070	COG0724	RNA recognition motif
CA733_RS05080	COG0724	RNA recognition motif
CA733_RS05085	COG3118	belongs to the thioredoxin family
CA733_RS05100	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CA733_RS05105	COG0724	RNA recognition motif
CA733_RS05110	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CA733_RS05130	COG3852	Histidine kinase
CA733_RS05145	COG1489	DNA binding
CA733_RS05170	COG0657	acetylesterase activity
CA733_RS05175	COG0557	exoribonuclease II activity
CA733_RS05180	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CA733_RS05185	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CA733_RS05205	COG0303	'Molybdopterin
CA733_RS05225	COG1252	NADH dehydrogenase
CA733_RS05235	COG0745	RESPONSE REGULATOR receiver
CA733_RS05250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CA733_RS05255	COG1104	cysteine desulfurase activity
CA733_RS05275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CA733_RS05280	COG0765	amino acid transport
CA733_RS05285	COG1126	abc transporter atp-binding protein
CA733_RS05295	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CA733_RS05300	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CA733_RS05300	COG0284	orotidine-5'-phosphate decarboxylase activity
CA733_RS05305	COG0628	permease
CA733_RS05350	COG0693	protein deglycase activity
CA733_RS05385	COG5398	heme oxygenase
CA733_RS05390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CA733_RS05425	COG1619	proteins homologs of microcin C7 resistance protein MccF
CA733_RS05440	COG4310	Domain of unknown function (DUF2172)
CA733_RS05445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CA733_RS05460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CA733_RS05465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CA733_RS05505	COG0495	leucyl-tRNA aminoacylation
CA733_RS05520	COG1595	DNA-templated transcription, initiation
CA733_RS05530	COG1376	ErfK ybiS ycfS ynhG family protein
CA733_RS05550	COG1136	(ABC) transporter
CA733_RS05565	COG0584	glycerophosphoryl diester phosphodiesterase
CA733_RS05595	COG0438	transferase activity, transferring glycosyl groups
CA733_RS05605	COG4783	chaperone-mediated protein folding
CA733_RS05640	COG0222	ribosome binding
CA733_RS05675	COG0714	Associated with various cellular activities
CA733_RS05685	COG1305	Transglutaminase-like
CA733_RS05710	COG0300	oxidoreductase activity
CA733_RS05735	COG0702	epimerase
CA733_RS05740	COG2205	protein histidine kinase activity
CA733_RS05740	COG3292	Two component regulator propeller
CA733_RS05740	COG0745	RESPONSE REGULATOR receiver
CA733_RS05750	COG0438	transferase activity, transferring glycosyl groups
CA733_RS05760	COG1063	alcohol dehydrogenase
CA733_RS05790	COG3128	pkhd-type hydroxylase
CA733_RS05795	COG0390	transport system, permease component
CA733_RS05820	COG5285	phytanoyl-CoA dioxygenase
CA733_RS05840	COG2217	Heavy metal translocating P-type atpase
CA733_RS05850	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS05850	COG0515	serine threonine protein kinase
CA733_RS05855	COG2319	Wd-40 repeat
CA733_RS05855	COG3903	Transcriptional regulator
CA733_RS05890	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA733_RS05905	COG0564	pseudouridine synthase activity
CA733_RS05915	COG2813	Specifically methylates the guanine in position
CA733_RS05935	COG0616	signal peptide processing
CA733_RS05945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CA733_RS05960	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CA733_RS05985	COG1160	GTP binding
CA733_RS05990	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CA733_RS05995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CA733_RS06005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CA733_RS06010	COG1799	cell septum assembly
CA733_RS06015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CA733_RS06020	COG4581	dead DEAH box helicase
CA733_RS06030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CA733_RS06060	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CA733_RS06070	COG0702	epimerase
CA733_RS06075	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CA733_RS06080	COG0745	RESPONSE REGULATOR receiver
CA733_RS06100	COG0134	indole-3-glycerol-phosphate synthase activity
CA733_RS06105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CA733_RS06130	COG0515	serine threonine protein kinase
CA733_RS06145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CA733_RS06150	COG1525	nuclease
CA733_RS06155	COG0483	inositol monophosphate 1-phosphatase activity
CA733_RS06165	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CA733_RS06170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA733_RS06180	COG0288	reversible hydration of carbon dioxide
CA733_RS06210	COG0419	ATPase involved in DNA repair
CA733_RS06250	COG5002	protein histidine kinase activity
CA733_RS06255	COG0151	Belongs to the GarS family
CA733_RS06310	COG0656	L-ascorbic acid biosynthetic process
CA733_RS06315	COG0693	protein deglycase activity
CA733_RS06355	COG2095	MarC family integral membrane protein
CA733_RS06365	COG1461	Dihydroxyacetone kinase
CA733_RS06375	COG2376	Dihydroxyacetone kinase
CA733_RS06500	COG2319	Wd-40 repeat
CA733_RS06500	COG3903	Transcriptional regulator
CA733_RS06515	COG1192	Involved in chromosome partitioning
CA733_RS06525	COG0418	dihydroorotase activity
CA733_RS06620	COG2856	Zn peptidase
CA733_RS06625	COG1426	Protein conserved in bacteria
CA733_RS06660	COG0426	domain, Protein
CA733_RS06660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CA733_RS06665	COG0745	RESPONSE REGULATOR receiver
CA733_RS06675	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CA733_RS06685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CA733_RS06695	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CA733_RS06740	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CA733_RS06745	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CA733_RS06755	COG0473	3-isopropylmalate dehydrogenase activity
CA733_RS06760	COG2373	Large extracellular alpha-helical protein
CA733_RS06770	COG4953	penicillin-binding protein 1C
CA733_RS06815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CA733_RS06825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA733_RS06855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA733_RS06865	COG1116	anion transmembrane transporter activity
CA733_RS06870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CA733_RS06885	COG0625	glutathione transferase activity
CA733_RS06890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA733_RS06895	COG1464	Belongs to the NlpA lipoprotein family
CA733_RS06920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA733_RS06925	COG1464	Belongs to the NlpA lipoprotein family
CA733_RS06930	COG1464	Belongs to the NlpA lipoprotein family
CA733_RS06955	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS06960	COG0667	Aldo Keto reductase
CA733_RS06965	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CA733_RS07000	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CA733_RS07005	COG0725	ABC transporter, periplasmic molybdate-binding protein
CA733_RS07030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CA733_RS07045	COG2201	protein-glutamate methylesterase activity
CA733_RS07060	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CA733_RS07070	COG0515	serine threonine protein kinase
CA733_RS07070	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS07075	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS07080	COG1247	-acetyltransferase
CA733_RS07100	COG1960	acyl-CoA dehydrogenase activity
CA733_RS07145	COG5002	protein histidine kinase activity
CA733_RS07155	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CA733_RS07165	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CA733_RS07175	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CA733_RS07185	COG1116	anion transmembrane transporter activity
CA733_RS07190	COG2010	Cytochrome c
CA733_RS07200	COG0742	ribosomal rna small subunit methyltransferase
CA733_RS07205	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CA733_RS07210	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CA733_RS07250	COG0589	response to stress
CA733_RS07265	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CA733_RS07275	COG2010	Cytochrome c
CA733_RS07285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CA733_RS07290	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CA733_RS07300	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CA733_RS07305	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CA733_RS07320	COG0697	spore germination
CA733_RS07330	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CA733_RS07340	COG4771	TonB-dependent receptor
CA733_RS07345	COG0515	serine threonine protein kinase
CA733_RS07345	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS07355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CA733_RS07365	COG3688	RNA-binding protein containing a PIN domain
CA733_RS07370	COG1122	ATPase activity
CA733_RS07385	COG2154	pterin-4-alpha-carbinolamine dehydratase
CA733_RS07390	COG3659	wide pore channel activity
CA733_RS07395	COG1959	2 iron, 2 sulfur cluster binding
CA733_RS07400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CA733_RS07405	COG0484	heat shock protein binding
CA733_RS07425	COG1970	mechanosensitive ion channel activity
CA733_RS07440	COG0308	aminopeptidase N
CA733_RS07610	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CA733_RS07615	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CA733_RS07620	COG0617	tRNA 3'-terminal CCA addition
CA733_RS07630	COG1214	PFAM Peptidase M22, glycoprotease
CA733_RS07680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CA733_RS07725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CA733_RS07735	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CA733_RS07740	COG0501	Belongs to the peptidase M48B family
CA733_RS07770	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CA733_RS07810	COG1215	transferase activity, transferring glycosyl groups
CA733_RS07820	COG0438	transferase activity, transferring glycosyl groups
CA733_RS07825	COG1216	Glycosyl transferase, family 2
CA733_RS07830	COG0438	transferase activity, transferring glycosyl groups
CA733_RS07850	COG0438	transferase activity, transferring glycosyl groups
CA733_RS07865	COG0489	protein tyrosine kinase activity
CA733_RS07880	COG2385	sporulation resulting in formation of a cellular spore
CA733_RS07905	COG0577	efflux transmembrane transporter activity
CA733_RS07905	COG1136	(ABC) transporter
CA733_RS07910	COG0811	peptide transport
CA733_RS07930	COG0318	PFAM AMP-dependent synthetase and ligase
CA733_RS07935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CA733_RS07940	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CA733_RS07945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CA733_RS07970	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CA733_RS07975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CA733_RS07975	COG0519	Catalyzes the synthesis of GMP from XMP
CA733_RS07985	COG1230	cation diffusion facilitator family transporter
CA733_RS08000	COG0436	Aminotransferase
CA733_RS08005	COG0457	Tetratricopeptide repeat
CA733_RS08005	COG0463	Glycosyl transferase, family 2
CA733_RS08020	COG4221	oxidoreductase activity
CA733_RS08025	COG0745	RESPONSE REGULATOR receiver
CA733_RS08030	COG5002	protein histidine kinase activity
CA733_RS08035	COG1252	NADH dehydrogenase
CA733_RS08055	COG2205	protein histidine kinase activity
CA733_RS08055	COG2202	Pas domain
CA733_RS08060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA733_RS08065	COG0668	transmembrane transport
CA733_RS08095	COG2205	protein histidine kinase activity
CA733_RS08095	COG2202	Pas domain
CA733_RS08105	COG2205	protein histidine kinase activity
CA733_RS08105	COG0784	Response regulator, receiver
CA733_RS08110	COG0183	Belongs to the thiolase family
CA733_RS08115	COG1615	UPF0182 protein
CA733_RS08130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CA733_RS08145	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CA733_RS08150	COG1522	sequence-specific DNA binding
CA733_RS08180	COG1132	(ABC) transporter
CA733_RS08220	COG1672	PFAM Archaeal ATPase
CA733_RS08220	COG2319	Wd-40 repeat
CA733_RS08275	COG2274	protein secretion by the type I secretion system
CA733_RS08310	COG1366	Belongs to the anti-sigma-factor antagonist family
CA733_RS08315	COG0745	RESPONSE REGULATOR receiver
CA733_RS08335	COG0745	RESPONSE REGULATOR receiver
CA733_RS08340	COG0492	ferredoxin-NADP+ reductase activity
CA733_RS08355	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CA733_RS08360	COG3321	synthase
CA733_RS08360	COG0300	oxidoreductase activity
CA733_RS08360	COG4221	oxidoreductase activity
CA733_RS08360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CA733_RS08375	COG0318	PFAM AMP-dependent synthetase and ligase
CA733_RS08405	COG5002	protein histidine kinase activity
CA733_RS08425	COG2205	protein histidine kinase activity
CA733_RS08425	COG0784	Response regulator, receiver
CA733_RS08505	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CA733_RS08515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CA733_RS08520	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CA733_RS08525	COG2080	2 iron, 2 sulfur cluster binding
CA733_RS08535	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CA733_RS08550	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CA733_RS08560	COG0714	Associated with various cellular activities
CA733_RS08580	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CA733_RS08585	COG2203	Gaf domain
CA733_RS08585	COG3706	GGDEF domain
CA733_RS08585	COG4251	negative regulation of phosphorylation
CA733_RS08585	COG5001	Diguanylate cyclase
CA733_RS08605	COG5002	protein histidine kinase activity
CA733_RS08610	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CA733_RS08615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CA733_RS08620	COG3977	Valine--pyruvate aminotransferase
CA733_RS08625	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CA733_RS08635	COG1733	regulation of RNA biosynthetic process
CA733_RS08640	COG2271	Major facilitator Superfamily
CA733_RS08645	COG0596	Alpha beta hydrolase
CA733_RS08655	COG0406	alpha-ribazole phosphatase activity
CA733_RS08665	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CA733_RS08680	COG2319	Wd-40 repeat
CA733_RS08680	COG5635	Nacht domain
CA733_RS08710	COG0430	RNA-3'-phosphate cyclase activity
CA733_RS08720	COG3335	DDE superfamily endonuclease
CA733_RS08755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CA733_RS08760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CA733_RS08795	COG0300	oxidoreductase activity
CA733_RS08800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA733_RS08905	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CA733_RS08910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CA733_RS08945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CA733_RS08960	COG2223	nitrite transmembrane transporter activity
CA733_RS08970	COG0456	acetyltransferase
CA733_RS09015	COG5002	protein histidine kinase activity
CA733_RS09020	COG0784	Response regulator, receiver
CA733_RS09025	COG4251	negative regulation of phosphorylation
CA733_RS09035	COG0730	response to heat
CA733_RS09065	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CA733_RS09075	COG4221	oxidoreductase activity
CA733_RS09095	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS09120	COG1040	competence protein
CA733_RS09130	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CA733_RS09140	COG0343	queuine tRNA-ribosyltransferase activity
CA733_RS09160	COG0589	response to stress
CA733_RS09165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CA733_RS09165	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CA733_RS09185	COG0596	Alpha beta hydrolase
CA733_RS09195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CA733_RS09200	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CA733_RS09210	COG0505	Belongs to the CarA family
CA733_RS09220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CA733_RS09285	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CA733_RS09290	COG0175	sulfate reduction
CA733_RS09295	COG0012	GTP binding
CA733_RS09320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CA733_RS09350	COG0367	asparagine synthase
CA733_RS09375	COG1846	Transcriptional regulator
CA733_RS09380	COG0515	serine threonine protein kinase
CA733_RS09380	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS09415	COG4636	protein conserved in cyanobacteria
CA733_RS09420	COG1361	Conserved repeat domain
CA733_RS09430	COG0556	nucleotide-excision repair
CA733_RS09435	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CA733_RS09440	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CA733_RS09470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CA733_RS09490	COG4242	Belongs to the peptidase S51 family
CA733_RS09500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CA733_RS09510	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CA733_RS09520	COG0655	NAD(P)H dehydrogenase (quinone) activity
CA733_RS09630	COG1215	transferase activity, transferring glycosyl groups
CA733_RS09635	COG5002	protein histidine kinase activity
CA733_RS09635	COG2198	Histidine kinase
CA733_RS09635	COG0784	Response regulator, receiver
CA733_RS09675	COG0110	maltose O-acetyltransferase activity
CA733_RS09705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA733_RS09730	COG0339	signal peptide processing
CA733_RS09735	COG0515	serine threonine protein kinase
CA733_RS09745	COG0631	protein serine/threonine phosphatase activity
CA733_RS09750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CA733_RS09755	COG3937	granule-associated protein
CA733_RS09790	COG2226	methyltransferase
CA733_RS09795	COG0789	Transcriptional regulator
CA733_RS09805	COG2217	Heavy metal translocating P-type atpase
CA733_RS09820	COG0488	(ABC) transporter
CA733_RS09835	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CA733_RS09850	COG1981	membrane
CA733_RS09855	COG0517	IMP dehydrogenase activity
CA733_RS09855	COG1994	Peptidase M50
CA733_RS09895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CA733_RS09900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA733_RS09905	COG2234	aminopeptidase activity
CA733_RS09910	COG5002	protein histidine kinase activity
CA733_RS09955	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CA733_RS09960	COG2723	6-phospho-beta-galactosidase activity
CA733_RS09985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CA733_RS09985	COG0426	domain, Protein
CA733_RS09995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CA733_RS09995	COG0426	domain, Protein
CA733_RS10010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CA733_RS10020	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS10040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CA733_RS10055	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CA733_RS10060	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CA733_RS10070	COG1160	GTP binding
CA733_RS10095	COG2815	serine threonine protein kinase
CA733_RS10095	COG0515	serine threonine protein kinase
CA733_RS10100	COG0693	protein deglycase activity
CA733_RS10100	COG0753	catalase activity
CA733_RS10115	COG2197	response regulator
CA733_RS10135	COG4999	Histidine kinase
CA733_RS10135	COG3850	Histidine kinase
CA733_RS10135	COG3437	response regulator, receiver
CA733_RS10135	COG2205	protein histidine kinase activity
CA733_RS10145	COG0784	Response regulator, receiver
CA733_RS10155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CA733_RS10195	COG0358	DNA primase activity
CA733_RS10205	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CA733_RS10210	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CA733_RS10235	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CA733_RS10260	COG1176	ABC-type spermidine putrescine transport system, permease component I
CA733_RS10265	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CA733_RS10275	COG3842	ATPase activity
CA733_RS10280	COG0768	penicillin binding
CA733_RS10285	COG0768	penicillin binding
CA733_RS10290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CA733_RS10295	COG0587	DNA-directed DNA polymerase activity
CA733_RS10350	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CA733_RS10355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CA733_RS10360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CA733_RS10400	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CA733_RS10405	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CA733_RS10410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CA733_RS10415	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CA733_RS10420	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CA733_RS10425	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CA733_RS10445	COG0438	transferase activity, transferring glycosyl groups
CA733_RS10465	COG2815	serine threonine protein kinase
CA733_RS10465	COG0515	serine threonine protein kinase
CA733_RS10485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CA733_RS10525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS10530	COG1464	Belongs to the NlpA lipoprotein family
CA733_RS10540	COG2011	ABC-type metal ion transport system permease component
CA733_RS10545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CA733_RS10555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS10580	COG2072	flavoprotein involved in K transport
CA733_RS10590	COG4122	O-methyltransferase activity
CA733_RS10615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS10630	COG2814	Major facilitator Superfamily
CA733_RS10635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA733_RS10650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA733_RS10660	COG2175	clavaminate synthase activity
CA733_RS10665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CA733_RS10680	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CA733_RS10685	COG0459	protein refolding
CA733_RS10700	COG0546	phosphoglycolate phosphatase activity
CA733_RS10705	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CA733_RS10720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CA733_RS10725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS10755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA733_RS10760	COG3292	Two component regulator propeller
CA733_RS10760	COG0745	RESPONSE REGULATOR receiver
CA733_RS10760	COG2205	protein histidine kinase activity
CA733_RS10770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CA733_RS10785	COG0745	RESPONSE REGULATOR receiver
CA733_RS10790	COG5002	protein histidine kinase activity
CA733_RS10845	COG1429	ligase activity, forming nitrogen-metal bonds
CA733_RS10880	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CA733_RS10885	COG1126	abc transporter atp-binding protein
CA733_RS10925	COG0587	DNA-directed DNA polymerase activity
CA733_RS10930	COG1301	dicarboxylic acid transport
CA733_RS10940	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CA733_RS10955	COG0438	transferase activity, transferring glycosyl groups
CA733_RS10980	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CA733_RS11040	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CA733_RS11070	COG1716	ATPase activity
CA733_RS11075	COG0363	glucosamine-6-phosphate deaminase activity
CA733_RS11115	COG0251	oxidation-reduction process
CA733_RS11125	COG1640	4-alpha-glucanotransferase
CA733_RS11130	COG1426	Protein conserved in bacteria
CA733_RS11135	COG1187	pseudouridine synthase activity
CA733_RS11145	COG0575	Belongs to the CDS family
CA733_RS11155	COG0515	serine threonine protein kinase
CA733_RS11160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CA733_RS11165	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CA733_RS11165	COG0189	ligase activity
CA733_RS11170	COG4242	Belongs to the peptidase S51 family
CA733_RS11175	COG0336	Belongs to the RNA methyltransferase TrmD family
CA733_RS11180	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CA733_RS11195	COG4166	transmembrane transport
CA733_RS11200	COG1691	(AIR) carboxylase
CA733_RS11210	COG0165	Argininosuccinate lyase
CA733_RS11225	COG0025	NhaP-type Na H and K H
CA733_RS11240	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CA733_RS11245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CA733_RS11245	COG0426	domain, Protein
CA733_RS11250	COG0426	domain, Protein
CA733_RS11250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CA733_RS11255	COG0724	RNA recognition motif
CA733_RS11265	COG1566	PFAM secretion protein HlyD family protein
CA733_RS11270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CA733_RS11280	COG0335	large ribosomal subunit rRNA binding
CA733_RS11290	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CA733_RS11295	COG0250	Participates in transcription elongation, termination and antitermination
CA733_RS11300	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CA733_RS11305	COG0081	regulation of translation
CA733_RS11310	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CA733_RS11315	COG0222	ribosome binding
CA733_RS11320	COG3266	domain, Protein
CA733_RS11320	COG0515	serine threonine protein kinase
CA733_RS11325	COG5002	protein histidine kinase activity
CA733_RS11330	COG0784	Response regulator, receiver
CA733_RS11330	COG5002	protein histidine kinase activity
CA733_RS11335	COG0667	Aldo Keto reductase
CA733_RS11350	COG1151	hydroxylamine reductase activity
CA733_RS11370	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CA733_RS11395	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CA733_RS11410	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CA733_RS11425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CA733_RS11430	COG5002	protein histidine kinase activity
CA733_RS11430	COG2198	Histidine kinase
CA733_RS11430	COG0784	Response regulator, receiver
CA733_RS11445	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CA733_RS11465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CA733_RS11610	COG2197	response regulator
CA733_RS11620	COG1253	flavin adenine dinucleotide binding
CA733_RS11625	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CA733_RS11675	COG0778	Nitroreductase
CA733_RS11680	COG0412	Dienelactone hydrolase
CA733_RS11685	COG1285	pathogenesis
CA733_RS11705	COG0438	transferase activity, transferring glycosyl groups
CA733_RS11725	COG1846	Transcriptional regulator
CA733_RS11755	COG2274	protein secretion by the type I secretion system
CA733_RS11765	COG1132	(ABC) transporter
CA733_RS11775	COG0667	Aldo Keto reductase
CA733_RS11800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA733_RS11805	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CA733_RS11810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CA733_RS11815	COG1116	anion transmembrane transporter activity
CA733_RS11850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS11915	COG0628	permease
CA733_RS11950	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CA733_RS11970	COG5002	protein histidine kinase activity
CA733_RS11990	COG3961	Belongs to the TPP enzyme family
CA733_RS12010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CA733_RS12015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CA733_RS12025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA733_RS12050	COG3335	DDE superfamily endonuclease
CA733_RS12100	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CA733_RS12105	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CA733_RS12130	COG0582	viral genome integration into host DNA
CA733_RS12165	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CA733_RS12180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CA733_RS12190	COG0432	Pfam Uncharacterised protein family UPF0047
CA733_RS12230	COG0542	response to heat
CA733_RS12250	COG4935	Belongs to the peptidase S8 family
CA733_RS12250	COG1404	Belongs to the peptidase S8 family
CA733_RS12265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CA733_RS12285	COG4585	Histidine kinase
CA733_RS12290	COG2197	response regulator
CA733_RS12305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CA733_RS12355	COG0318	PFAM AMP-dependent synthetase and ligase
CA733_RS12385	COG0300	oxidoreductase activity
CA733_RS12460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA733_RS12465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CA733_RS12475	COG0640	Transcriptional regulator
CA733_RS12490	COG0446	pyridine nucleotide-disulphide oxidoreductase
CA733_RS12495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CA733_RS12505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CA733_RS12535	COG2319	Wd-40 repeat
CA733_RS12535	COG4249	Peptidase C14 caspase catalytic subunit p20
CA733_RS12605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CA733_RS12610	COG0673	inositol 2-dehydrogenase activity
CA733_RS12645	COG1222	aaa ATPase
CA733_RS12685	COG0784	Response regulator, receiver
CA733_RS12685	COG2205	protein histidine kinase activity
CA733_RS12730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CA733_RS12780	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CA733_RS12790	COG0121	glutamine amidotransferase
CA733_RS12795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CA733_RS12815	COG1131	(ABC) transporter
CA733_RS12825	COG1309	transcriptional regulator
CA733_RS12830	COG0723	plastoquinol--plastocyanin reductase activity
CA733_RS12835	COG2076	Multidrug Resistance protein
CA733_RS12840	COG2205	protein histidine kinase activity
CA733_RS12860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CA733_RS12900	COG2226	methyltransferase
CA733_RS12905	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CA733_RS12905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CA733_RS12925	COG0393	Putative heavy-metal-binding
CA733_RS12930	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CA733_RS12935	COG5002	protein histidine kinase activity
CA733_RS12940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CA733_RS12955	COG2203	Gaf domain
CA733_RS12955	COG5001	Diguanylate cyclase
CA733_RS12955	COG3706	GGDEF domain
CA733_RS12955	COG4251	negative regulation of phosphorylation
CA733_RS12965	COG3540	Alkaline phosphatase
CA733_RS12975	COG1982	Orn Lys Arg decarboxylase major
CA733_RS12980	COG1063	alcohol dehydrogenase
CA733_RS12995	COG3000	fatty acid hydroxylase
CA733_RS12995	COG0300	oxidoreductase activity
CA733_RS13000	COG0745	RESPONSE REGULATOR receiver
CA733_RS13005	COG0429	hydrolase of the alpha beta-hydrolase fold
CA733_RS13010	COG2091	lysine biosynthetic process via aminoadipic acid
CA733_RS13030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CA733_RS13030	COG3320	Male sterility
CA733_RS13035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CA733_RS13035	COG2070	2-Nitropropane dioxygenase
CA733_RS13040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CA733_RS13040	COG0300	oxidoreductase activity
CA733_RS13040	COG3321	synthase
CA733_RS13040	COG4221	oxidoreductase activity
CA733_RS13050	COG4221	oxidoreductase activity
CA733_RS13050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CA733_RS13050	COG3321	synthase
CA733_RS13050	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS13055	COG3321	synthase
CA733_RS13055	COG0604	alcohol dehydrogenase
CA733_RS13080	COG2852	Protein conserved in bacteria
CA733_RS13085	COG1475	DNA binding
CA733_RS13090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA733_RS13150	COG1695	Transcriptional regulator
CA733_RS13235	COG0515	serine threonine protein kinase
CA733_RS13235	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS13250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CA733_RS13255	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CA733_RS13270	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CA733_RS13275	COG0406	alpha-ribazole phosphatase activity
CA733_RS13280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CA733_RS13305	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CA733_RS13340	COG0768	penicillin binding
CA733_RS13365	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CA733_RS13375	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CA733_RS13380	COG4636	protein conserved in cyanobacteria
CA733_RS13400	COG0542	response to heat
CA733_RS13425	COG1773	rubredoxin
CA733_RS13430	COG2081	HI0933 family
CA733_RS13435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CA733_RS13440	COG0463	Glycosyl transferase, family 2
CA733_RS13460	COG1215	transferase activity, transferring glycosyl groups
CA733_RS13465	COG1215	transferase activity, transferring glycosyl groups
CA733_RS13475	COG0489	protein tyrosine kinase activity
CA733_RS13480	COG1361	Conserved repeat domain
CA733_RS13510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CA733_RS13515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CA733_RS13520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CA733_RS13525	COG2048	Heterodisulfide reductase, subunit B
CA733_RS13530	COG0071	Belongs to the small heat shock protein (HSP20) family
CA733_RS13535	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CA733_RS13540	COG4585	Histidine kinase
CA733_RS13550	COG0643	Histidine kinase
CA733_RS13550	COG0784	Response regulator, receiver
CA733_RS13550	COG2198	Histidine kinase
CA733_RS13555	COG2203	Gaf domain
CA733_RS13555	COG0840	transmembrane signaling receptor activity
CA733_RS13570	COG2201	protein-glutamate methylesterase activity
CA733_RS13575	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CA733_RS13600	COG0784	Response regulator, receiver
CA733_RS13600	COG5002	protein histidine kinase activity
CA733_RS13605	COG0731	radical SAM domain protein
CA733_RS13620	COG0438	transferase activity, transferring glycosyl groups
CA733_RS13630	COG1215	transferase activity, transferring glycosyl groups
CA733_RS13645	COG1121	(ABC) transporter
CA733_RS13650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CA733_RS13670	COG0583	DNA-binding transcription factor activity
CA733_RS13680	COG0730	response to heat
CA733_RS13685	COG0671	phosphoesterase, PA-phosphatase related
CA733_RS13695	COG0330	HflC and HflK could
CA733_RS13705	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
CA733_RS13715	COG0667	Aldo Keto reductase
CA733_RS13725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CA733_RS13730	COG0581	inorganic phosphate transmembrane transporter activity
CA733_RS13735	COG0573	inorganic phosphate transmembrane transporter activity
CA733_RS13740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CA733_RS13760	COG1619	proteins homologs of microcin C7 resistance protein MccF
CA733_RS13775	COG1309	transcriptional regulator
CA733_RS13790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CA733_RS13795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CA733_RS13800	COG0573	inorganic phosphate transmembrane transporter activity
CA733_RS13805	COG0581	inorganic phosphate transmembrane transporter activity
CA733_RS13810	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CA733_RS13815	COG5002	protein histidine kinase activity
CA733_RS13835	COG0395	ABC-type sugar transport system, permease component
CA733_RS13840	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CA733_RS13845	COG5322	oxidoreductase activity
CA733_RS13850	COG0825	malonyl-CoA metabolic process
CA733_RS13855	COG0300	oxidoreductase activity
CA733_RS13860	COG0302	gtp cyclohydrolase
CA733_RS13865	COG0135	phosphoribosylanthranilate isomerase activity
CA733_RS13880	COG0517	IMP dehydrogenase activity
CA733_RS13880	COG1994	Peptidase M50
CA733_RS13885	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CA733_RS13885	COG0617	tRNA 3'-terminal CCA addition
CA733_RS13885	COG0517	IMP dehydrogenase activity
CA733_RS13895	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CA733_RS13910	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CA733_RS13915	COG3239	Fatty acid desaturase
CA733_RS13920	COG3239	Fatty acid desaturase
CA733_RS13930	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CA733_RS13940	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
CA733_RS13970	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CA733_RS13970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CA733_RS13985	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CA733_RS13990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CA733_RS14030	COG0671	phosphoesterase, PA-phosphatase related
CA733_RS14035	COG2207	Transcriptional regulator
CA733_RS14050	COG4221	oxidoreductase activity
CA733_RS14055	COG0667	Aldo Keto reductase
CA733_RS14085	COG0415	Belongs to the DNA photolyase family
CA733_RS14090	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CA733_RS14095	COG0745	RESPONSE REGULATOR receiver
CA733_RS14100	COG1132	(ABC) transporter
CA733_RS14105	COG1132	(ABC) transporter
CA733_RS14125	COG2815	serine threonine protein kinase
CA733_RS14125	COG0515	serine threonine protein kinase
CA733_RS14140	COG0288	reversible hydration of carbon dioxide
CA733_RS14150	COG0463	Glycosyl transferase, family 2
CA733_RS14155	COG0398	Pfam SNARE associated Golgi protein
CA733_RS14175	COG3437	response regulator, receiver
CA733_RS14180	COG0784	Response regulator, receiver
CA733_RS14180	COG5002	protein histidine kinase activity
CA733_RS14180	COG2198	Histidine kinase
CA733_RS14185	COG3693	PFAM glycoside hydrolase, family 10
CA733_RS14210	COG5002	protein histidine kinase activity
CA733_RS14220	COG0745	RESPONSE REGULATOR receiver
CA733_RS14260	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CA733_RS14265	COG1192	Involved in chromosome partitioning
CA733_RS14300	COG0783	Belongs to the Dps family
CA733_RS14305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CA733_RS14310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CA733_RS14320	COG0494	nUDIX hydrolase
CA733_RS14325	COG0516	GMP reductase activity
CA733_RS14325	COG0517	IMP dehydrogenase activity
CA733_RS14355	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CA733_RS14385	COG0779	Required for maturation of 30S ribosomal subunits
CA733_RS14390	COG0195	Participates in both transcription termination and antitermination
CA733_RS14400	COG3266	domain, Protein
CA733_RS14400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CA733_RS14415	COG1361	Conserved repeat domain
CA733_RS14440	COG3240	lipase activity
CA733_RS14465	COG2205	protein histidine kinase activity
CA733_RS14470	COG3706	GGDEF domain
CA733_RS14470	COG5001	Diguanylate cyclase
CA733_RS14470	COG4251	negative regulation of phosphorylation
CA733_RS14470	COG2203	Gaf domain
CA733_RS14495	COG2201	protein-glutamate methylesterase activity
CA733_RS14500	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CA733_RS14505	COG5002	protein histidine kinase activity
CA733_RS14545	COG1054	Belongs to the UPF0176 family
CA733_RS14575	COG2197	response regulator
CA733_RS14580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CA733_RS14660	COG1361	Conserved repeat domain
CA733_RS14675	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CA733_RS14680	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CA733_RS14680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CA733_RS14705	COG0151	Belongs to the GarS family
CA733_RS14745	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CA733_RS14760	COG1304	FMN binding
CA733_RS14765	COG0616	signal peptide processing
CA733_RS14780	COG2319	Wd-40 repeat
CA733_RS14780	COG4249	Peptidase C14 caspase catalytic subunit p20
CA733_RS14790	COG2239	Acts as a magnesium transporter
CA733_RS14805	COG0540	Belongs to the ATCase OTCase family
CA733_RS14810	COG0542	response to heat
CA733_RS14815	COG0515	serine threonine protein kinase
CA733_RS14825	COG3540	Alkaline phosphatase
CA733_RS14835	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CA733_RS14855	COG0443	Heat shock 70 kDa protein
CA733_RS14870	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS14875	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CA733_RS14885	COG0612	Peptidase, M16
CA733_RS14900	COG1950	PFAM Membrane protein of
CA733_RS14915	COG1832	CoA-binding protein
CA733_RS14925	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CA733_RS14940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CA733_RS14980	COG3706	GGDEF domain
CA733_RS14980	COG2203	Gaf domain
CA733_RS14980	COG4251	negative regulation of phosphorylation
CA733_RS14980	COG5001	Diguanylate cyclase
CA733_RS14985	COG1131	(ABC) transporter
CA733_RS14985	COG1716	ATPase activity
CA733_RS14985	COG0842	Transport permease protein
CA733_RS14990	COG3266	domain, Protein
CA733_RS14990	COG0515	serine threonine protein kinase
CA733_RS15035	COG0346	lactoylglutathione lyase activity
CA733_RS15040	COG0435	Glutathione S-transferase
CA733_RS15060	COG5002	protein histidine kinase activity
CA733_RS15060	COG2198	Histidine kinase
CA733_RS15060	COG0784	Response regulator, receiver
CA733_RS15065	COG0412	Dienelactone hydrolase
CA733_RS15080	COG2124	cytochrome p450
CA733_RS15095	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS15110	COG0316	Belongs to the HesB IscA family
CA733_RS15115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CA733_RS15125	COG5420	small protein containing a coiled-coil domain
CA733_RS15140	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CA733_RS15145	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CA733_RS15250	COG2831	hemolysin activation secretion protein
CA733_RS15255	COG3210	domain, Protein
CA733_RS15305	COG0667	Aldo Keto reductase
CA733_RS15310	COG3240	lipase activity
CA733_RS15355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CA733_RS15365	COG0454	-acetyltransferase
CA733_RS15380	COG1649	PFAM Uncharacterised BCR, COG1649
CA733_RS15440	COG1690	Belongs to the RtcB family
CA733_RS15445	COG2226	methyltransferase
CA733_RS15450	COG0546	phosphoglycolate phosphatase activity
CA733_RS15475	COG3584	3D domain protein
CA733_RS15525	COG0657	acetylesterase activity
CA733_RS15545	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CA733_RS15550	COG0596	Alpha beta hydrolase
CA733_RS15555	COG2258	MOSC domain
CA733_RS15560	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS15575	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CA733_RS15590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CA733_RS15590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CA733_RS15595	COG2197	response regulator
CA733_RS15600	COG0515	serine threonine protein kinase
CA733_RS15600	COG2815	serine threonine protein kinase
CA733_RS15620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CA733_RS15625	COG1881	PFAM PEBP family protein
CA733_RS15655	COG0625	glutathione transferase activity
CA733_RS15690	COG0535	radical SAM domain protein
CA733_RS15720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CA733_RS15770	COG2890	protein-(glutamine-N5) methyltransferase activity
CA733_RS15775	COG0625	glutathione transferase activity
CA733_RS15790	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CA733_RS15790	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CA733_RS15795	COG3386	PFAM SMP-30 Gluconolaconase
CA733_RS15810	COG0730	response to heat
CA733_RS15815	COG0730	response to heat
CA733_RS15895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CA733_RS15990	COG0745	RESPONSE REGULATOR receiver
CA733_RS16025	COG3631	Ketosteroid isomerase-related protein
CA733_RS16070	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS16215	COG2274	protein secretion by the type I secretion system
CA733_RS16255	COG4221	oxidoreductase activity
CA733_RS16260	COG2814	Major facilitator Superfamily
CA733_RS16275	COG0346	lactoylglutathione lyase activity
CA733_RS16280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CA733_RS16280	COG3453	Protein conserved in bacteria
CA733_RS16305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS16315	COG1053	succinate dehydrogenase
CA733_RS16320	COG0667	Aldo Keto reductase
CA733_RS16325	COG3659	wide pore channel activity
CA733_RS16330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS16340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS16345	COG2175	clavaminate synthase activity
CA733_RS16365	COG0302	gtp cyclohydrolase
CA733_RS16375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS16420	COG2226	methyltransferase
CA733_RS16425	COG4106	trans-aconitate 2-methyltransferase activity
CA733_RS16445	COG0697	spore germination
CA733_RS16450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA733_RS16455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA733_RS16460	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS16470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CA733_RS16475	COG0604	alcohol dehydrogenase
CA733_RS16490	COG1247	-acetyltransferase
CA733_RS16495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CA733_RS16500	COG0154	amidase activity
CA733_RS16505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CA733_RS16515	COG0573	inorganic phosphate transmembrane transporter activity
CA733_RS16520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CA733_RS16525	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CA733_RS16545	COG2815	serine threonine protein kinase
CA733_RS16545	COG0515	serine threonine protein kinase
CA733_RS16565	COG2814	Major facilitator Superfamily
CA733_RS16580	COG1120	ATPase activity
CA733_RS16585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CA733_RS16590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CA733_RS16605	COG0848	biopolymer transport protein
CA733_RS16610	COG0811	peptide transport
CA733_RS16630	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CA733_RS16645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CA733_RS16700	COG2226	methyltransferase
CA733_RS16715	COG0515	serine threonine protein kinase
CA733_RS16715	COG2815	serine threonine protein kinase
CA733_RS16725	COG0412	Dienelactone hydrolase
CA733_RS16750	COG0129	dihydroxy-acid dehydratase activity
CA733_RS16755	COG0625	glutathione transferase activity
CA733_RS16780	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CA733_RS16785	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CA733_RS16800	COG0822	iron-sulfur transferase activity
CA733_RS16800	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CA733_RS16800	COG2906	2 iron, 2 sulfur cluster binding
CA733_RS16825	COG4251	negative regulation of phosphorylation
CA733_RS16825	COG5001	Diguanylate cyclase
CA733_RS16825	COG3706	GGDEF domain
CA733_RS16825	COG2203	Gaf domain
CA733_RS16835	COG2198	Histidine kinase
CA733_RS16835	COG0784	Response regulator, receiver
CA733_RS16835	COG0643	Histidine kinase
CA733_RS16840	COG0840	transmembrane signaling receptor activity
CA733_RS16840	COG2203	Gaf domain
CA733_RS16875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CA733_RS16960	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CA733_RS16970	COG0784	Response regulator, receiver
CA733_RS16970	COG2205	protein histidine kinase activity
CA733_RS16975	COG0745	RESPONSE REGULATOR receiver
CA733_RS16980	COG1595	DNA-templated transcription, initiation
CA733_RS17025	COG0436	Aminotransferase
CA733_RS17030	COG1181	Belongs to the D-alanine--D-alanine ligase family
CA733_RS17035	COG1181	Belongs to the D-alanine--D-alanine ligase family
CA733_RS17045	COG1181	Belongs to the D-alanine--D-alanine ligase family
CA733_RS17070	COG3292	Two component regulator propeller
CA733_RS17070	COG2205	protein histidine kinase activity
CA733_RS17070	COG0745	RESPONSE REGULATOR receiver
CA733_RS17075	COG2201	protein-glutamate methylesterase activity
CA733_RS17080	COG0643	Histidine kinase
CA733_RS17080	COG2198	Histidine kinase
CA733_RS17080	COG0784	Response regulator, receiver
CA733_RS17090	COG0840	transmembrane signaling receptor activity
CA733_RS17100	COG0835	chemotaxis
CA733_RS17110	COG2211	Major facilitator Superfamily
CA733_RS17130	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CA733_RS17275	COG3335	DDE superfamily endonuclease
CA733_RS17315	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CA733_RS17330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CA733_RS17345	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CA733_RS17350	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CA733_RS17360	COG0546	phosphoglycolate phosphatase activity
CA733_RS17380	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CA733_RS17400	COG1722	exodeoxyribonuclease VII activity
CA733_RS17405	COG1570	exodeoxyribonuclease VII activity
CA733_RS17415	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CA733_RS17420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CA733_RS17445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CA733_RS17470	COG0748	coenzyme F420 binding
CA733_RS17485	COG0751	glycine-tRNA ligase activity
CA733_RS17490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CA733_RS17500	COG0515	serine threonine protein kinase
CA733_RS17500	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS17505	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS17505	COG0515	serine threonine protein kinase
CA733_RS17530	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CA733_RS17570	COG3206	protein involved in exopolysaccharide biosynthesis
CA733_RS17570	COG0489	protein tyrosine kinase activity
CA733_RS17595	COG0784	Response regulator, receiver
CA733_RS17595	COG2198	Histidine kinase
CA733_RS17595	COG2205	protein histidine kinase activity
CA733_RS17610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CA733_RS17615	COG0745	RESPONSE REGULATOR receiver
CA733_RS17620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CA733_RS17625	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CA733_RS17630	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CA733_RS17635	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CA733_RS17640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CA733_RS17645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CA733_RS17650	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CA733_RS17660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CA733_RS17665	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CA733_RS17670	COG0511	ligase activity, forming carbon-carbon bonds
CA733_RS17675	COG0640	Transcriptional regulator
CA733_RS17685	COG0442	prolyl-tRNA aminoacylation
CA733_RS17720	COG5554	nitrogen fixation
CA733_RS17725	COG5554	nitrogen fixation
CA733_RS17730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CA733_RS17745	COG1045	serine acetyltransferase
CA733_RS17785	COG0537	adenosine 5'-monophosphoramidase activity
CA733_RS17860	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CA733_RS17860	COG0392	lysyltransferase activity
CA733_RS17870	COG4251	negative regulation of phosphorylation
CA733_RS17875	COG0784	Response regulator, receiver
CA733_RS17890	COG0519	Catalyzes the synthesis of GMP from XMP
CA733_RS17900	COG1132	(ABC) transporter
CA733_RS17930	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CA733_RS17945	COG0316	Belongs to the HesB IscA family
CA733_RS17960	COG1090	epimerase
CA733_RS17975	COG2217	Heavy metal translocating P-type atpase
CA733_RS18000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CA733_RS18005	COG0363	glucosamine-6-phosphate deaminase activity
CA733_RS18015	COG1254	Belongs to the acylphosphatase family
CA733_RS18025	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CA733_RS18030	COG0191	fructose-bisphosphate aldolase activity
CA733_RS18055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CA733_RS18085	COG0003	Pfam Anion-transporting ATPase
CA733_RS18090	COG4251	negative regulation of phosphorylation
CA733_RS18090	COG3706	GGDEF domain
CA733_RS18090	COG2203	Gaf domain
CA733_RS18090	COG5001	Diguanylate cyclase
CA733_RS18090	COG2203	Gaf domain
CA733_RS18090	COG5001	Diguanylate cyclase
CA733_RS18090	COG4251	negative regulation of phosphorylation
CA733_RS18090	COG3706	GGDEF domain
CA733_RS18095	COG0592	DNA-directed DNA polymerase activity
CA733_RS18100	COG1032	radical SAM domain protein
CA733_RS18110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CA733_RS18115	COG0724	RNA recognition motif
CA733_RS18120	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CA733_RS18125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA733_RS18130	COG0242	peptide deformylase activity
CA733_RS18140	COG2217	Heavy metal translocating P-type atpase
CA733_RS18160	COG0157	Belongs to the NadC ModD family
CA733_RS18190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CA733_RS18195	COG0572	uridine kinase
CA733_RS18200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CA733_RS18205	COG0460	homoserine dehydrogenase
CA733_RS18215	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CA733_RS18220	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CA733_RS18250	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CA733_RS18260	COG3959	Transketolase, thiamine diphosphate binding domain
CA733_RS18270	COG3447	MASE1 domain protein
CA733_RS18270	COG5001	Diguanylate cyclase
CA733_RS18270	COG5002	protein histidine kinase activity
CA733_RS18275	COG5002	protein histidine kinase activity
CA733_RS18295	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CA733_RS18300	COG0686	Belongs to the AlaDH PNT family
CA733_RS18310	COG1131	(ABC) transporter
CA733_RS18325	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CA733_RS18335	COG1492	cobalamin metabolic process
CA733_RS18355	COG0667	Aldo Keto reductase
CA733_RS18360	COG0765	amino acid transport
CA733_RS18365	COG0415	Belongs to the DNA photolyase family
CA733_RS18375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CA733_RS18390	COG1104	cysteine desulfurase activity
CA733_RS18410	COG3335	DDE superfamily endonuclease
CA733_RS18420	COG0481	GTPase activity
CA733_RS18430	COG3850	Histidine kinase
CA733_RS18430	COG2205	protein histidine kinase activity
CA733_RS18430	COG4999	Histidine kinase
CA733_RS18430	COG3437	response regulator, receiver
CA733_RS18435	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CA733_RS18460	COG0405	Gamma-glutamyltransferase
CA733_RS18480	COG3903	Transcriptional regulator
CA733_RS18480	COG2319	Wd-40 repeat
CA733_RS18485	COG2815	serine threonine protein kinase
CA733_RS18485	COG0515	serine threonine protein kinase
CA733_RS18495	COG2843	Capsule synthesis protein
CA733_RS18500	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CA733_RS18530	COG0159	tryptophan synthase activity
CA733_RS18540	COG2321	neutral zinc metallopeptidase
CA733_RS18570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA733_RS18720	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA733_RS18740	COG2124	cytochrome p450
CA733_RS18745	COG2267	carboxylic ester hydrolase activity
CA733_RS18750	COG2022	thiamine diphosphate biosynthetic process
CA733_RS18750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CA733_RS18765	COG3920	Histidine kinase
CA733_RS18795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CA733_RS18815	COG2755	lipolytic protein G-D-S-L family
CA733_RS18815	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CA733_RS18860	COG0747	negative chemotaxis
CA733_RS18880	COG3386	PFAM SMP-30 Gluconolaconase
CA733_RS18920	COG0667	Aldo Keto reductase
CA733_RS18925	COG0783	Belongs to the Dps family
CA733_RS18930	COG1741	Belongs to the pirin family
CA733_RS18940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA733_RS18950	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS18955	COG1773	rubredoxin
CA733_RS18960	COG1408	metallophosphoesterase
CA733_RS19045	COG1408	metallophosphoesterase
CA733_RS19055	COG0484	heat shock protein binding
CA733_RS19060	COG0484	heat shock protein binding
CA733_RS19090	COG0784	Response regulator, receiver
CA733_RS19090	COG2205	protein histidine kinase activity
CA733_RS19110	COG1914	H( )-stimulated, divalent metal cation uptake system
CA733_RS19190	COG0745	RESPONSE REGULATOR receiver
CA733_RS19195	COG0697	spore germination
CA733_RS19200	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CA733_RS19220	COG0681	Belongs to the peptidase S26 family
CA733_RS19245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CA733_RS19250	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CA733_RS19255	COG0284	orotidine-5'-phosphate decarboxylase activity
CA733_RS19265	COG1573	uracil-dna glycosylase
CA733_RS19280	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CA733_RS19300	COG0587	DNA-directed DNA polymerase activity
CA733_RS19305	COG0154	amidase activity
CA733_RS19310	COG1073	alpha beta
CA733_RS19345	COG0386	Belongs to the glutathione peroxidase family
CA733_RS19360	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CA733_RS19360	COG0678	peroxiredoxin activity
CA733_RS19425	COG0297	glycogen (starch) synthase activity
CA733_RS19435	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CA733_RS19480	COG0745	RESPONSE REGULATOR receiver
CA733_RS19495	COG0138	bifunctional purine biosynthesis protein purh
CA733_RS19505	COG3536	Protein conserved in bacteria
CA733_RS19510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CA733_RS19535	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CA733_RS19540	COG0830	nickel cation binding
CA733_RS19545	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CA733_RS19580	COG3903	Transcriptional regulator
CA733_RS19580	COG2319	Wd-40 repeat
CA733_RS19590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CA733_RS19605	COG0667	Aldo Keto reductase
CA733_RS19615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA733_RS19625	COG1131	(ABC) transporter
CA733_RS19630	COG1129	ABC transporter
CA733_RS19630	COG0842	Transport permease protein
CA733_RS19635	COG0842	Transport permease protein
CA733_RS19640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CA733_RS19650	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CA733_RS19655	COG0052	Belongs to the universal ribosomal protein uS2 family
CA733_RS19680	COG0137	argininosuccinate synthase activity
CA733_RS19685	COG0586	Pfam SNARE associated Golgi protein
CA733_RS19700	COG0360	Binds together with S18 to 16S ribosomal RNA
CA733_RS19705	COG0179	Fumarylacetoacetate (FAA) hydrolase
CA733_RS19720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CA733_RS19725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CA733_RS19730	COG1546	Belongs to the CinA family
CA733_RS19730	COG1058	Belongs to the CinA family
CA733_RS19740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS19745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CA733_RS19750	COG1116	anion transmembrane transporter activity
CA733_RS19750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS19760	COG1116	anion transmembrane transporter activity
CA733_RS19770	COG1597	lipid kinase activity
CA733_RS19785	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CA733_RS19795	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CA733_RS19800	COG0563	adenylate kinase activity
CA733_RS19815	COG0717	Belongs to the dCTP deaminase family
CA733_RS19825	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CA733_RS19845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CA733_RS19860	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CA733_RS19885	COG3976	FMN-binding domain protein
CA733_RS19885	COG1053	succinate dehydrogenase
CA733_RS19905	COG1131	(ABC) transporter
CA733_RS19975	COG0659	secondary active sulfate transmembrane transporter activity
CA733_RS20015	COG1012	belongs to the aldehyde dehydrogenase family
CA733_RS20020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA733_RS20025	COG3956	TIGRFAM MazG family protein
CA733_RS20090	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CA733_RS20095	COG0732	type I restriction modification DNA specificity domain
CA733_RS20105	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CA733_RS20140	COG3265	gluconokinase activity
CA733_RS20150	COG1252	NADH dehydrogenase
CA733_RS20155	COG1904	glucuronate isomerase
CA733_RS20160	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS20170	COG1899	peptidyl-lysine modification to peptidyl-hypusine
CA733_RS20175	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CA733_RS20205	COG1846	Transcriptional regulator
CA733_RS20210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CA733_RS20215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CA733_RS20220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CA733_RS20225	COG4956	integral membrane protein (PIN domain superfamily)
CA733_RS20240	COG0346	lactoylglutathione lyase activity
CA733_RS20255	COG2304	oxidoreductase activity
CA733_RS20260	COG2304	oxidoreductase activity
CA733_RS20265	COG0740	serine-type endopeptidase activity
CA733_RS20270	COG0740	serine-type endopeptidase activity
CA733_RS20360	COG0312	modulator of DNA gyrase
CA733_RS20375	COG0237	dephospho-CoA kinase activity
CA733_RS20380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CA733_RS20390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CA733_RS20395	COG2226	methyltransferase
CA733_RS20400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CA733_RS20405	COG0569	domain protein
CA733_RS20445	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CA733_RS20455	COG0792	nuclease activity
CA733_RS20470	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CA733_RS20475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CA733_RS20495	COG0745	RESPONSE REGULATOR receiver
CA733_RS20510	COG5002	protein histidine kinase activity
CA733_RS20555	COG3266	domain, Protein
CA733_RS20555	COG2911	Protein conserved in bacteria
CA733_RS20555	COG1361	Conserved repeat domain
CA733_RS20575	COG0583	DNA-binding transcription factor activity
CA733_RS20610	COG1429	ligase activity, forming nitrogen-metal bonds
CA733_RS20665	COG0435	Glutathione S-transferase
CA733_RS20675	COG3659	wide pore channel activity
CA733_RS20685	COG2261	transglycosylase associated protein
CA733_RS20700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CA733_RS20720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS20745	COG1079	Belongs to the binding-protein-dependent transport system permease family
CA733_RS20750	COG4603	Belongs to the binding-protein-dependent transport system permease family
CA733_RS20755	COG1480	7TM receptor with intracellular HD hydrolase
CA733_RS20790	COG0535	radical SAM domain protein
CA733_RS20825	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CA733_RS20840	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CA733_RS20850	COG0784	Response regulator, receiver
CA733_RS20855	COG0121	glutamine amidotransferase
CA733_RS21005	COG3541	Predicted nucleotidyltransferase
CA733_RS21010	COG2363	Small membrane protein
CA733_RS21020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CA733_RS21035	COG2319	Wd-40 repeat
CA733_RS21035	COG3903	Transcriptional regulator
CA733_RS21045	COG0589	response to stress
CA733_RS21045	COG0475	glutathione-regulated potassium exporter activity
CA733_RS21065	COG0538	isocitrate dehydrogenase activity
CA733_RS21070	COG0515	serine threonine protein kinase
CA733_RS21085	COG0492	ferredoxin-NADP+ reductase activity
CA733_RS21090	COG1252	NADH dehydrogenase
CA733_RS21095	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CA733_RS21100	COG0633	Ferredoxin
CA733_RS21105	COG0316	Belongs to the HesB IscA family
CA733_RS21110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CA733_RS21120	COG5420	small protein containing a coiled-coil domain
CA733_RS21135	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CA733_RS21145	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CA733_RS21155	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CA733_RS21160	COG2906	2 iron, 2 sulfur cluster binding
CA733_RS21160	COG0822	iron-sulfur transferase activity
CA733_RS21160	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CA733_RS21165	COG1104	cysteine desulfurase activity
CA733_RS21175	COG0535	radical SAM domain protein
CA733_RS21175	COG1433	Dinitrogenase iron-molybdenum cofactor
CA733_RS21180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CA733_RS21185	COG5554	nitrogen fixation
CA733_RS21200	COG3842	ATPase activity
CA733_RS21210	COG1175	transmembrane transport
CA733_RS21215	COG1653	transport
CA733_RS21225	COG0038	chloride channel
CA733_RS21245	COG0438	transferase activity, transferring glycosyl groups
CA733_RS21260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CA733_RS21275	COG2201	protein-glutamate methylesterase activity
CA733_RS21290	COG0643	Histidine kinase
CA733_RS21290	COG2198	Histidine kinase
CA733_RS21290	COG0784	Response regulator, receiver
CA733_RS21300	COG0745	RESPONSE REGULATOR receiver
CA733_RS21310	COG0784	Response regulator, receiver
CA733_RS21310	COG2205	protein histidine kinase activity
CA733_RS21335	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CA733_RS21405	COG1959	2 iron, 2 sulfur cluster binding
CA733_RS21420	COG1554	hydrolase, family 65, central catalytic
CA733_RS21425	COG0438	transferase activity, transferring glycosyl groups
CA733_RS21455	COG1181	Belongs to the D-alanine--D-alanine ligase family
CA733_RS21465	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CA733_RS21480	COG2046	Belongs to the sulfate adenylyltransferase family
CA733_RS21500	COG0482	sulfurtransferase activity
CA733_RS21510	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CA733_RS21510	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CA733_RS21550	COG1836	PFAM Integral membrane protein DUF92
CA733_RS21580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CA733_RS21585	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CA733_RS21660	COG1132	(ABC) transporter
CA733_RS21690	COG1702	phosphate starvation-inducible protein PhoH
CA733_RS21695	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CA733_RS21705	COG0228	four-way junction DNA binding
CA733_RS21710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CA733_RS21715	COG0006	proline dipeptidase activity
CA733_RS21735	COG0384	phenazine biosynthesis protein PhzF
CA733_RS21755	COG0612	Peptidase, M16
CA733_RS21760	COG0612	Peptidase, M16
CA733_RS21810	COG4191	Histidine kinase
CA733_RS21830	COG0024	Methionine aminopeptidase
CA733_RS21835	COG0673	inositol 2-dehydrogenase activity
CA733_RS21850	COG2385	sporulation resulting in formation of a cellular spore
CA733_RS21860	COG0783	Belongs to the Dps family
CA733_RS21875	COG0745	RESPONSE REGULATOR receiver
CA733_RS21890	COG0515	serine threonine protein kinase
CA733_RS21905	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CA733_RS21910	COG0814	amino acid
CA733_RS21935	COG1595	DNA-templated transcription, initiation
CA733_RS21940	COG2815	serine threonine protein kinase
CA733_RS21940	COG0515	serine threonine protein kinase
CA733_RS21965	COG3706	GGDEF domain
CA733_RS21965	COG5001	Diguanylate cyclase
CA733_RS21965	COG2203	Gaf domain
CA733_RS21965	COG4251	negative regulation of phosphorylation
CA733_RS21975	COG1217	gtp-binding protein TYPA
CA733_RS21995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CA733_RS22010	COG1252	NADH dehydrogenase
CA733_RS22015	COG5002	protein histidine kinase activity
CA733_RS22025	COG0277	FAD linked oxidase domain protein
CA733_RS22030	COG0247	lactate metabolic process
CA733_RS22045	COG0515	serine threonine protein kinase
CA733_RS22045	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS22050	COG1177	transmembrane transport
CA733_RS22055	COG0438	transferase activity, transferring glycosyl groups
CA733_RS22060	COG0784	Response regulator, receiver
CA733_RS22070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CA733_RS22080	COG0515	serine threonine protein kinase
CA733_RS22080	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS22095	COG0438	transferase activity, transferring glycosyl groups
CA733_RS22110	COG1132	(ABC) transporter
CA733_RS22120	COG0515	serine threonine protein kinase
CA733_RS22120	COG2815	serine threonine protein kinase
CA733_RS22125	COG2124	cytochrome p450
CA733_RS22130	COG1192	Involved in chromosome partitioning
CA733_RS22155	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CA733_RS22185	COG0009	L-threonylcarbamoyladenylate synthase
CA733_RS22190	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CA733_RS22215	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CA733_RS22220	COG0321	lipoyl(octanoyl) transferase activity
CA733_RS22255	COG1012	belongs to the aldehyde dehydrogenase family
CA733_RS22265	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS22285	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CA733_RS22305	COG0443	Heat shock 70 kDa protein
CA733_RS22325	COG0572	uridine kinase
CA733_RS22355	COG1215	transferase activity, transferring glycosyl groups
CA733_RS22370	COG4251	negative regulation of phosphorylation
CA733_RS22375	COG0784	Response regulator, receiver
CA733_RS22380	COG2205	protein histidine kinase activity
CA733_RS22385	COG5001	Diguanylate cyclase
CA733_RS22385	COG3706	GGDEF domain
CA733_RS22385	COG2203	Gaf domain
CA733_RS22385	COG4251	negative regulation of phosphorylation
CA733_RS22415	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CA733_RS22420	COG0713	ATP synthesis coupled electron transport
CA733_RS22425	COG0839	Belongs to the complex I subunit 6 family
CA733_RS22430	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA733_RS22435	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CA733_RS22440	COG0372	Belongs to the citrate synthase family
CA733_RS22445	COG2062	phosphohistidine phosphatase, SixA
CA733_RS22460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CA733_RS22470	COG0784	Response regulator, receiver
CA733_RS22485	COG5001	Diguanylate cyclase
CA733_RS22485	COG4251	negative regulation of phosphorylation
CA733_RS22485	COG3706	GGDEF domain
CA733_RS22485	COG2203	Gaf domain
CA733_RS22490	COG0643	Histidine kinase
CA733_RS22490	COG0784	Response regulator, receiver
CA733_RS22490	COG2198	Histidine kinase
CA733_RS22500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CA733_RS22525	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CA733_RS22540	COG1696	Membrane protein involved in D-alanine export
CA733_RS22550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CA733_RS22550	COG0456	acetyltransferase
CA733_RS22555	COG0671	phosphoesterase, PA-phosphatase related
CA733_RS22570	COG2274	protein secretion by the type I secretion system
CA733_RS22595	COG0723	plastoquinol--plastocyanin reductase activity
CA733_RS22605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CA733_RS22610	COG0805	protein transport
CA733_RS22620	COG0741	lytic transglycosylase activity
CA733_RS22630	COG2205	protein histidine kinase activity
CA733_RS22630	COG3437	response regulator, receiver
CA733_RS22630	COG3850	Histidine kinase
CA733_RS22630	COG4999	Histidine kinase
CA733_RS22635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CA733_RS22645	COG0217	transcriptional regulatory protein
CA733_RS22655	COG0469	pyruvate kinase activity
CA733_RS22695	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CA733_RS22710	COG0671	phosphoesterase, PA-phosphatase related
CA733_RS22730	COG1473	amidohydrolase
CA733_RS22735	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CA733_RS22740	COG0515	serine threonine protein kinase
CA733_RS22745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CA733_RS22750	COG2264	protein methyltransferase activity
CA733_RS22765	COG1132	(ABC) transporter
CA733_RS22775	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CA733_RS22810	COG2897	thiosulfate sulfurtransferase activity
CA733_RS22820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CA733_RS22830	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CA733_RS22845	COG0515	serine threonine protein kinase
CA733_RS22845	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS22855	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CA733_RS22910	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS22920	COG0598	Magnesium transport protein CorA
CA733_RS22925	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CA733_RS22930	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS22930	COG0515	serine threonine protein kinase
CA733_RS22940	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CA733_RS22955	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CA733_RS22960	COG2226	methyltransferase
CA733_RS22970	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CA733_RS22975	COG2319	Wd-40 repeat
CA733_RS22975	COG3903	Transcriptional regulator
CA733_RS22985	COG0745	RESPONSE REGULATOR receiver
CA733_RS22990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CA733_RS23015	COG2770	Histidine kinase
CA733_RS23015	COG3437	response regulator, receiver
CA733_RS23030	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CA733_RS23040	COG0436	Aminotransferase
CA733_RS23065	COG1530	ribonuclease E activity
CA733_RS23070	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CA733_RS23085	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CA733_RS23090	COG0051	transcription antitermination factor activity, RNA binding
CA733_RS23095	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CA733_RS23100	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CA733_RS23105	COG0049	tRNA binding
CA733_RS23110	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CA733_RS23115	COG0316	Belongs to the HesB IscA family
CA733_RS23130	COG0069	glutamate synthase activity
CA733_RS23130	COG0067	glutamate synthase
CA733_RS23130	COG0070	glutamate synthase
CA733_RS23170	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CA733_RS23190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CA733_RS23205	COG0440	acetolactate synthase activity
CA733_RS23220	COG3321	synthase
CA733_RS23220	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS23220	COG0604	alcohol dehydrogenase
CA733_RS23255	COG2319	Wd-40 repeat
CA733_RS23255	COG3903	Transcriptional regulator
CA733_RS23260	COG0514	ATP-dependent DNA helicase (RecQ)
CA733_RS23315	COG1049	propionate catabolic process, 2-methylcitrate cycle
CA733_RS23320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CA733_RS23330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CA733_RS23395	COG0071	Belongs to the small heat shock protein (HSP20) family
CA733_RS23425	COG2815	serine threonine protein kinase
CA733_RS23425	COG0515	serine threonine protein kinase
CA733_RS23445	COG0720	synthase
CA733_RS23455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CA733_RS23455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CA733_RS23465	COG0515	serine threonine protein kinase
CA733_RS23465	COG2815	serine threonine protein kinase
CA733_RS23525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CA733_RS23535	COG0803	Belongs to the bacterial solute-binding protein 9 family
CA733_RS23535	COG3443	Belongs to the bacterial solute-binding protein 9 family
CA733_RS23540	COG3659	wide pore channel activity
CA733_RS23555	COG5002	protein histidine kinase activity
CA733_RS23565	COG0745	RESPONSE REGULATOR receiver
CA733_RS23590	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CA733_RS23600	COG0113	porphobilinogen synthase activity
CA733_RS23610	COG0508	dehydrogenase complex catalyzes the overall conversion of
CA733_RS23610	COG0022	dehydrogenase e1 component
CA733_RS23615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CA733_RS23620	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CA733_RS23630	COG0454	-acetyltransferase
CA733_RS23635	COG5002	protein histidine kinase activity
CA733_RS23645	COG2890	protein-(glutamine-N5) methyltransferase activity
CA733_RS23660	COG0454	-acetyltransferase
CA733_RS23675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CA733_RS23695	COG0194	GDP metabolic process
CA733_RS23700	COG2052	Domain of unknown function (DUF370)
CA733_RS23705	COG1305	Transglutaminase-like
CA733_RS23725	COG0142	geranyltranstransferase activity
CA733_RS23735	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CA733_RS23740	COG0860	N-Acetylmuramoyl-L-alanine amidase
CA733_RS23745	COG0860	N-Acetylmuramoyl-L-alanine amidase
CA733_RS23745	COG2247	cell wall binding repeat
CA733_RS23750	COG0475	glutathione-regulated potassium exporter activity
CA733_RS23760	COG0629	single-stranded DNA binding
CA733_RS23765	COG1077	Cell shape determining protein MreB Mrl
CA733_RS23780	COG3659	wide pore channel activity
CA733_RS23795	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CA733_RS23805	COG1295	ribonuclease BN
CA733_RS23830	COG1233	COG1233 Phytoene dehydrogenase and related
CA733_RS23840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CA733_RS23845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CA733_RS23850	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CA733_RS23865	COG0697	spore germination
CA733_RS23870	COG0306	phosphate transporter
CA733_RS23875	COG1063	alcohol dehydrogenase
CA733_RS23880	COG2226	methyltransferase
CA733_RS23880	COG1073	alpha beta
CA733_RS23890	COG0745	RESPONSE REGULATOR receiver
CA733_RS23895	COG2226	methyltransferase
CA733_RS23905	COG3659	wide pore channel activity
CA733_RS23910	COG5002	protein histidine kinase activity
CA733_RS23915	COG3706	GGDEF domain
CA733_RS23915	COG2203	Gaf domain
CA733_RS23915	COG5001	Diguanylate cyclase
CA733_RS23915	COG4251	negative regulation of phosphorylation
CA733_RS23945	COG0431	NADPH-dependent FMN reductase
CA733_RS23950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CA733_RS23990	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CA733_RS23990	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CA733_RS24015	COG2177	Part of the ABC transporter FtsEX involved in
CA733_RS24045	COG1393	Belongs to the ArsC family
CA733_RS24055	COG2183	response to ionizing radiation
CA733_RS24065	COG1950	PFAM Membrane protein of
CA733_RS24085	COG2010	Cytochrome c
CA733_RS24090	COG0656	L-ascorbic acid biosynthetic process
CA733_RS24095	COG4572	Cation transport regulator
CA733_RS24100	COG0783	Belongs to the Dps family
CA733_RS24110	COG0574	Belongs to the PEP-utilizing enzyme family
CA733_RS24110	COG3848	Pyruvate phosphate dikinase
CA733_RS24120	COG2202	Pas domain
CA733_RS24120	COG2205	protein histidine kinase activity
CA733_RS24135	COG0735	belongs to the Fur family
CA733_RS24140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CA733_RS24160	COG4294	response to UV
CA733_RS24180	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CA733_RS24250	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA733_RS24260	COG3259	Nickel-dependent hydrogenase
CA733_RS24290	COG0123	including yeast histone deacetylase and acetoin utilization protein
CA733_RS24305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CA733_RS24310	COG1505	serine-type exopeptidase activity
CA733_RS24315	COG0643	Histidine kinase
CA733_RS24315	COG0784	Response regulator, receiver
CA733_RS24315	COG2198	Histidine kinase
CA733_RS24315	COG0784	Response regulator, receiver
CA733_RS24315	COG0643	Histidine kinase
CA733_RS24315	COG2198	Histidine kinase
CA733_RS24320	COG0840	transmembrane signaling receptor activity
CA733_RS24345	COG0037	tRNA processing
CA733_RS24365	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CA733_RS24370	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CA733_RS24375	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CA733_RS24380	COG5002	protein histidine kinase activity
CA733_RS24405	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CA733_RS24415	COG1116	anion transmembrane transporter activity
CA733_RS24420	COG1116	anion transmembrane transporter activity
CA733_RS24420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS24425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CA733_RS24430	COG0784	Response regulator, receiver
CA733_RS24430	COG2205	protein histidine kinase activity
CA733_RS24445	COG0571	ribonuclease III activity
CA733_RS24455	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CA733_RS24455	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CA733_RS24465	COG0670	Belongs to the BI1 family
CA733_RS24485	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CA733_RS24490	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CA733_RS24495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CA733_RS24495	COG0512	Glutamine amidotransferase of anthranilate synthase
CA733_RS24510	COG0006	proline dipeptidase activity
CA733_RS24515	COG3629	intracellular signal transduction
CA733_RS24515	COG3903	Transcriptional regulator
CA733_RS24545	COG2202	Pas domain
CA733_RS24545	COG2205	protein histidine kinase activity
CA733_RS24585	COG3794	PFAM blue (type 1) copper domain protein
CA733_RS24590	COG2010	Cytochrome c
CA733_RS24595	COG2010	Cytochrome c
CA733_RS24605	COG0395	ABC-type sugar transport system, permease component
CA733_RS24615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CA733_RS24630	COG0515	serine threonine protein kinase
CA733_RS24630	COG2815	serine threonine protein kinase
CA733_RS24635	COG0515	serine threonine protein kinase
CA733_RS24635	COG2815	serine threonine protein kinase
CA733_RS24640	COG2203	Gaf domain
CA733_RS24640	COG4251	negative regulation of phosphorylation
CA733_RS24640	COG5001	Diguanylate cyclase
CA733_RS24640	COG3706	GGDEF domain
CA733_RS24645	COG0515	serine threonine protein kinase
CA733_RS24645	COG2815	serine threonine protein kinase
CA733_RS24650	COG0515	serine threonine protein kinase
CA733_RS24650	COG2815	serine threonine protein kinase
CA733_RS24665	COG1007	ATP synthesis coupled electron transport
CA733_RS24720	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CA733_RS24725	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CA733_RS24730	COG0235	Class ii aldolase
CA733_RS24745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CA733_RS24745	COG0574	Belongs to the PEP-utilizing enzyme family
CA733_RS24760	COG4251	negative regulation of phosphorylation
CA733_RS24765	COG0784	Response regulator, receiver
CA733_RS24770	COG5002	protein histidine kinase activity
CA733_RS24795	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CA733_RS24800	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CA733_RS24825	COG3848	Pyruvate phosphate dikinase
CA733_RS24825	COG0574	Belongs to the PEP-utilizing enzyme family
CA733_RS24860	COG0288	reversible hydration of carbon dioxide
CA733_RS24875	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA733_RS24880	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA733_RS24885	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA733_RS24890	COG1773	rubredoxin
CA733_RS24895	COG4447	cellulose binding
CA733_RS24955	COG2319	Wd-40 repeat
CA733_RS24955	COG4249	Peptidase C14 caspase catalytic subunit p20
CA733_RS24975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CA733_RS24980	COG0189	ligase activity
CA733_RS24985	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CA733_RS24995	COG3751	2OG-Fe(II) oxygenase superfamily
CA733_RS25000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CA733_RS25010	COG0793	Belongs to the peptidase S41A family
CA733_RS25015	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CA733_RS25040	COG1388	LysM domain
CA733_RS25040	COG4942	peptidase
CA733_RS25045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA733_RS25060	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CA733_RS25065	COG0859	PFAM glycosyl transferase family 9
CA733_RS25090	COG2197	response regulator
CA733_RS25105	COG0170	dolichyl monophosphate biosynthetic process
CA733_RS25110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CA733_RS25115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CA733_RS25120	COG0776	regulation of translation
CA733_RS25125	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS25130	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CA733_RS25135	COG0509	glycine decarboxylation via glycine cleavage system
CA733_RS25140	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CA733_RS25140	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CA733_RS25200	COG1022	Amp-dependent synthetase and ligase
CA733_RS25205	COG1250	3-hydroxyacyl-CoA dehydrogenase
CA733_RS25205	COG1024	Enoyl-CoA hydratase
CA733_RS25210	COG0183	Belongs to the thiolase family
CA733_RS25215	COG1960	acyl-CoA dehydrogenase activity
CA733_RS25220	COG0564	pseudouridine synthase activity
CA733_RS25240	COG0653	protein targeting
CA733_RS25250	COG0714	Associated with various cellular activities
CA733_RS25255	COG0196	riboflavin kinase activity
CA733_RS25260	COG1234	tRNA 3'-trailer cleavage
CA733_RS25265	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CA733_RS25270	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CA733_RS25275	COG0514	ATP-dependent DNA helicase (RecQ)
CA733_RS25290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CA733_RS25305	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS25305	COG0515	serine threonine protein kinase
CA733_RS25320	COG2304	oxidoreductase activity
CA733_RS25330	COG0167	dihydroorotate dehydrogenase activity
CA733_RS25350	COG1446	asparaginase
CA733_RS25355	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CA733_RS25365	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CA733_RS25370	COG0798	PFAM Bile acid sodium symporter
CA733_RS25380	COG3437	response regulator, receiver
CA733_RS25385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CA733_RS25385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CA733_RS25395	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CA733_RS25400	COG4783	chaperone-mediated protein folding
CA733_RS25415	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CA733_RS25425	COG1234	tRNA 3'-trailer cleavage
CA733_RS25440	COG0525	valine-tRNA ligase activity
CA733_RS25450	COG2814	Major facilitator Superfamily
CA733_RS25455	COG2971	BadF BadG BcrA BcrD
CA733_RS25460	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CA733_RS25465	COG1070	Carbohydrate kinase
CA733_RS25495	COG1666	GTP binding
CA733_RS25505	COG0857	belongs to the CobB CobQ family
CA733_RS25530	COG1215	transferase activity, transferring glycosyl groups
CA733_RS25535	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CA733_RS25550	COG1733	regulation of RNA biosynthetic process
CA733_RS25575	COG2045	Belongs to the ComB family
CA733_RS25595	COG1132	(ABC) transporter
CA733_RS25605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CA733_RS25610	COG2226	methyltransferase
CA733_RS25615	COG0438	transferase activity, transferring glycosyl groups
CA733_RS25625	COG1216	Glycosyl transferase, family 2
CA733_RS25645	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CA733_RS25675	COG0488	(ABC) transporter
CA733_RS25695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CA733_RS25735	COG2319	Wd-40 repeat
CA733_RS25735	COG3903	Transcriptional regulator
CA733_RS25740	COG0784	Response regulator, receiver
CA733_RS25740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA733_RS25740	COG2205	protein histidine kinase activity
CA733_RS25740	COG2198	Histidine kinase
CA733_RS25755	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CA733_RS25760	COG0745	RESPONSE REGULATOR receiver
CA733_RS25765	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CA733_RS25790	COG1160	GTP binding
CA733_RS25820	COG1606	tRNA processing
CA733_RS25850	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CA733_RS25860	COG2885	chlorophyll binding
CA733_RS25865	COG2885	chlorophyll binding
CA733_RS25875	COG2066	Belongs to the glutaminase family
CA733_RS25880	COG0508	dehydrogenase complex catalyzes the overall conversion of
CA733_RS25900	COG1022	Amp-dependent synthetase and ligase
CA733_RS25925	COG2070	2-Nitropropane dioxygenase
CA733_RS25940	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CA733_RS25945	COG0408	coproporphyrinogen oxidase activity
CA733_RS25950	COG5398	heme oxygenase
CA733_RS25985	COG2082	Precorrin-8x methylmutase
CA733_RS25995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CA733_RS26015	COG2239	Acts as a magnesium transporter
CA733_RS26020	COG2133	pyrroloquinoline quinone binding
CA733_RS26030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CA733_RS26035	COG0398	Pfam SNARE associated Golgi protein
CA733_RS26040	COG0398	Pfam SNARE associated Golgi protein
CA733_RS26055	COG4249	Peptidase C14 caspase catalytic subunit p20
CA733_RS26055	COG2319	Wd-40 repeat
CA733_RS26080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CA733_RS26105	COG4191	Histidine kinase
CA733_RS26110	COG5002	protein histidine kinase activity
CA733_RS26115	COG0788	formyltetrahydrofolate deformylase activity
CA733_RS26135	COG1131	(ABC) transporter
CA733_RS26160	COG0328	RNA-DNA hybrid ribonuclease activity
CA733_RS26180	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CA733_RS26185	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CA733_RS26200	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CA733_RS26210	COG0393	Putative heavy-metal-binding
CA733_RS26220	COG1131	(ABC) transporter
CA733_RS26270	COG4251	negative regulation of phosphorylation
CA733_RS26270	COG2203	Gaf domain
CA733_RS26270	COG5001	Diguanylate cyclase
CA733_RS26270	COG3706	GGDEF domain
CA733_RS26285	COG0277	FAD linked oxidase domain protein
CA733_RS26300	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CA733_RS26305	COG1372	Participates in initiation and elongation during chromosome replication
CA733_RS26305	COG0187	DNA topoisomerase II activity
CA733_RS26315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CA733_RS26320	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CA733_RS26330	COG0419	ATPase involved in DNA repair
CA733_RS26350	COG1361	Conserved repeat domain
CA733_RS26355	COG2205	protein histidine kinase activity
CA733_RS26380	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CA733_RS26385	COG0750	zinc metalloprotease
CA733_RS26390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CA733_RS26395	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CA733_RS26405	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CA733_RS26415	COG1459	type II secretion system
CA733_RS26425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CA733_RS26430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CA733_RS26440	COG0443	Heat shock 70 kDa protein
CA733_RS26445	COG0484	heat shock protein binding
CA733_RS26455	COG1162	GTPase activity
CA733_RS26460	COG1543	Belongs to the glycosyl hydrolase 57 family
CA733_RS26475	COG0443	Heat shock 70 kDa protein
CA733_RS26490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CA733_RS26495	COG0167	dihydroorotate dehydrogenase activity
CA733_RS26500	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CA733_RS26500	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CA733_RS26500	COG0674	pyruvate-flavodoxin oxidoreductase activity
CA733_RS26500	COG1013	pyruvate-flavodoxin oxidoreductase activity
CA733_RS26520	COG0612	Peptidase, M16
CA733_RS26545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CA733_RS26575	COG1192	Involved in chromosome partitioning
CA733_RS26580	COG0052	Belongs to the universal ribosomal protein uS2 family
CA733_RS26590	COG2003	Belongs to the UPF0758 family
CA733_RS26605	COG2197	response regulator
CA733_RS26610	COG0784	Response regulator, receiver
CA733_RS26610	COG2198	Histidine kinase
CA733_RS26610	COG2205	protein histidine kinase activity
CA733_RS26620	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CA733_RS26625	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CA733_RS26645	COG3237	CsbD-like
CA733_RS26655	COG3437	response regulator, receiver
CA733_RS26655	COG3850	Histidine kinase
CA733_RS26655	COG4999	Histidine kinase
CA733_RS26655	COG2205	protein histidine kinase activity
CA733_RS26660	COG2197	response regulator
CA733_RS26685	COG5002	protein histidine kinase activity
CA733_RS26700	COG1968	undecaprenyl-diphosphatase activity
CA733_RS26710	COG1555	photosystem II stabilization
CA733_RS26715	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CA733_RS26740	COG4243	Vitamin k epoxide reductase
CA733_RS26745	COG0434	BtpA family
CA733_RS26755	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CA733_RS26760	COG0513	Belongs to the DEAD box helicase family
CA733_RS26775	COG0483	inositol monophosphate 1-phosphatase activity
CA733_RS26785	COG1063	alcohol dehydrogenase
CA733_RS26795	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CA733_RS26800	COG0003	Pfam Anion-transporting ATPase
CA733_RS26820	COG0438	transferase activity, transferring glycosyl groups
CA733_RS26820	COG1216	Glycosyl transferase, family 2
CA733_RS26845	COG0438	transferase activity, transferring glycosyl groups
CA733_RS26860	COG0469	pyruvate kinase activity
CA733_RS26875	COG0515	serine threonine protein kinase
CA733_RS26875	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS26880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CA733_RS26905	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
CA733_RS26915	COG2132	Multicopper oxidase
CA733_RS26920	COG0205	6-phosphofructokinase activity
CA733_RS26955	COG0601	transmembrane transport
CA733_RS26960	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CA733_RS26975	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CA733_RS26985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CA733_RS26990	COG1268	BioY protein
CA733_RS26995	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CA733_RS27000	COG0573	inorganic phosphate transmembrane transporter activity
CA733_RS27005	COG0581	inorganic phosphate transmembrane transporter activity
CA733_RS27010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CA733_RS27015	COG1201	RNA secondary structure unwinding
CA733_RS27030	COG0523	cobalamin synthesis protein
CA733_RS27040	COG2166	iron-sulfur cluster assembly
CA733_RS27045	COG0646	methionine synthase
CA733_RS27045	COG1410	methionine synthase
CA733_RS27060	COG0528	UMP kinase activity
CA733_RS27065	COG0233	cytoplasmic translational termination
CA733_RS27070	COG0492	ferredoxin-NADP+ reductase activity
CA733_RS27085	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CA733_RS27115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CA733_RS27120	COG0758	DNA mediated transformation
CA733_RS27120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CA733_RS27130	COG3609	addiction module antidote protein, CC2985 family
CA733_RS27145	COG2171	N-acyltransferase activity
CA733_RS27155	COG0300	oxidoreductase activity
CA733_RS27165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CA733_RS27170	COG0535	radical SAM domain protein
CA733_RS27185	COG4948	Mandelate Racemase Muconate Lactonizing
CA733_RS27195	COG0494	nUDIX hydrolase
CA733_RS27205	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CA733_RS27240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CA733_RS27275	COG0300	oxidoreductase activity
CA733_RS27285	COG1136	(ABC) transporter
CA733_RS27285	COG0577	efflux transmembrane transporter activity
CA733_RS27290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA733_RS27310	COG1136	(ABC) transporter
CA733_RS27315	COG1136	(ABC) transporter
CA733_RS27315	COG0577	efflux transmembrane transporter activity
CA733_RS27335	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CA733_RS27345	COG2205	protein histidine kinase activity
CA733_RS27355	COG4251	negative regulation of phosphorylation
CA733_RS27360	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CA733_RS27395	COG0110	maltose O-acetyltransferase activity
CA733_RS27400	COG5001	Diguanylate cyclase
CA733_RS27400	COG5002	protein histidine kinase activity
CA733_RS27400	COG3447	MASE1 domain protein
CA733_RS27405	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CA733_RS27410	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CA733_RS27430	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CA733_RS27450	COG1842	Phage shock protein A
CA733_RS27455	COG1842	Phage shock protein A
CA733_RS27460	COG3118	belongs to the thioredoxin family
CA733_RS27465	COG0436	Aminotransferase
CA733_RS27475	COG0322	excinuclease ABC activity
CA733_RS27485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CA733_RS27495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CA733_RS27510	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CA733_RS27530	COG0523	cobalamin synthesis protein
CA733_RS27535	COG0215	cysteine-tRNA ligase activity
CA733_RS27545	COG0312	modulator of DNA gyrase
CA733_RS27550	COG0515	serine threonine protein kinase
CA733_RS27560	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CA733_RS27565	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CA733_RS27590	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CA733_RS27605	COG0745	RESPONSE REGULATOR receiver
CA733_RS27610	COG5002	protein histidine kinase activity
CA733_RS27615	COG0704	Plays a role in the regulation of phosphate uptake
CA733_RS27620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CA733_RS27625	COG3659	wide pore channel activity
CA733_RS27650	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CA733_RS27665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CA733_RS27665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CA733_RS27675	COG0561	phosphatase activity
CA733_RS27680	COG0018	arginyl-trna synthetase
CA733_RS27685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CA733_RS27690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CA733_RS27695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CA733_RS27700	COG0515	serine threonine protein kinase
CA733_RS27705	COG0583	DNA-binding transcription factor activity
CA733_RS27715	COG3118	belongs to the thioredoxin family
CA733_RS27720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CA733_RS27725	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA733_RS27745	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CA733_RS27755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CA733_RS27770	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CA733_RS27780	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CA733_RS27790	COG1285	pathogenesis
CA733_RS27795	COG0574	Belongs to the PEP-utilizing enzyme family
CA733_RS27795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CA733_RS27800	COG2319	Wd-40 repeat
CA733_RS27815	COG0784	Response regulator, receiver
CA733_RS27815	COG5002	protein histidine kinase activity
CA733_RS27820	COG0784	Response regulator, receiver
CA733_RS27825	COG4251	negative regulation of phosphorylation
CA733_RS27830	COG4251	negative regulation of phosphorylation
CA733_RS27845	COG1122	ATPase activity
CA733_RS27855	COG0310	cobalt ion transport
CA733_RS27860	COG2132	Multicopper oxidase
CA733_RS27890	COG0672	)-iron permease
CA733_RS27900	COG0746	molybdenum cofactor guanylyltransferase activity
CA733_RS27905	COG1331	Highly conserved protein containing a thioredoxin domain
CA733_RS27935	COG0300	oxidoreductase activity
CA733_RS27940	COG0740	serine-type endopeptidase activity
CA733_RS27945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CA733_RS27950	COG0683	leucine binding
CA733_RS27955	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CA733_RS27960	COG2319	Wd-40 repeat
CA733_RS27960	COG3903	Transcriptional regulator
CA733_RS27975	COG0163	prenyltransferase activity
CA733_RS27980	COG0557	exoribonuclease II activity
CA733_RS28000	COG0259	pyridoxamine-phosphate oxidase activity
CA733_RS28005	COG0628	permease
CA733_RS28015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CA733_RS28020	COG1166	arginine decarboxylase activity
CA733_RS28025	COG0105	UTP biosynthetic process
CA733_RS28030	COG0861	Integral membrane protein TerC family
CA733_RS28040	COG2319	Wd-40 repeat
CA733_RS28040	COG4249	Peptidase C14 caspase catalytic subunit p20
CA733_RS28050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CA733_RS28065	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CA733_RS28070	COG0395	ABC-type sugar transport system, permease component
CA733_RS28075	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CA733_RS28100	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CA733_RS28125	COG2226	methyltransferase
CA733_RS28130	COG0583	DNA-binding transcription factor activity
CA733_RS28140	COG0826	peptidase U32
CA733_RS28155	COG4636	protein conserved in cyanobacteria
CA733_RS28170	COG0307	riboflavin synthase, alpha
CA733_RS28175	COG0739	heme binding
CA733_RS28175	COG0741	lytic transglycosylase activity
CA733_RS28175	COG1196	nuclear chromosome segregation
CA733_RS28180	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CA733_RS28180	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CA733_RS28185	COG1496	oxidoreductase activity
CA733_RS28200	COG0154	amidase activity
CA733_RS28220	COG4106	trans-aconitate 2-methyltransferase activity
CA733_RS28235	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CA733_RS28240	COG0667	Aldo Keto reductase
CA733_RS28260	COG0840	transmembrane signaling receptor activity
CA733_RS28260	COG2203	Gaf domain
CA733_RS28265	COG5002	protein histidine kinase activity
CA733_RS28315	COG1032	radical SAM domain protein
CA733_RS28325	COG0180	Tryptophanyl-tRNA synthetase
CA733_RS28375	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA733_RS28380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CA733_RS28385	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CA733_RS28390	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CA733_RS28395	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CA733_RS28400	COG4451	ribulose bisphosphate carboxylase, small
CA733_RS28400	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CA733_RS28405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CA733_RS28410	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CA733_RS28415	COG0583	DNA-binding transcription factor activity
CA733_RS28445	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CA733_RS28465	COG0784	Response regulator, receiver
CA733_RS28465	COG2205	protein histidine kinase activity
CA733_RS28475	COG2267	carboxylic ester hydrolase activity
CA733_RS28510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CA733_RS28515	COG0193	aminoacyl-tRNA hydrolase activity
CA733_RS28520	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CA733_RS28530	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CA733_RS28550	COG1404	Belongs to the peptidase S8 family
CA733_RS28560	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CA733_RS28605	COG3300	MHYT domain
CA733_RS28605	COG5001	Diguanylate cyclase
CA733_RS28630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CA733_RS28660	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CA733_RS28680	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CA733_RS28685	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CA733_RS28725	COG0330	HflC and HflK could
CA733_RS28730	COG0735	belongs to the Fur family
CA733_RS28735	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CA733_RS28740	COG0047	phosphoribosylformylglycinamidine synthase activity
CA733_RS28750	COG0459	protein refolding
CA733_RS28755	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CA733_RS28765	COG0745	RESPONSE REGULATOR receiver
CA733_RS28780	COG0017	Asparaginyl-tRNA synthetase
CA733_RS28800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CA733_RS28815	COG0450	alkyl hydroperoxide reductase
CA733_RS28825	COG0625	glutathione transferase activity
CA733_RS28835	COG0484	heat shock protein binding
CA733_RS28845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CA733_RS28860	COG1218	3'(2'),5'-bisphosphate nucleotidase
CA733_RS28865	COG0724	RNA recognition motif
CA733_RS28870	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CA733_RS28895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CA733_RS28910	COG0312	modulator of DNA gyrase
CA733_RS28970	COG3237	CsbD-like
CA733_RS28975	COG2261	transglycosylase associated protein
CA733_RS28995	COG0673	inositol 2-dehydrogenase activity
CA733_RS29000	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CA733_RS29010	COG0189	ligase activity
CA733_RS29010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CA733_RS29020	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CA733_RS29030	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CA733_RS29035	COG0829	nickel cation binding
CA733_RS29040	COG0831	urea catabolic process
CA733_RS29045	COG0832	Belongs to the urease beta subunit family
CA733_RS29055	COG0804	urea catabolic process
CA733_RS29080	COG1012	belongs to the aldehyde dehydrogenase family
CA733_RS29085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CA733_RS29090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CA733_RS29115	COG3335	DDE superfamily endonuclease
CA733_RS29125	COG0464	growth
CA733_RS29135	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CA733_RS29140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CA733_RS29145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CA733_RS29150	COG0544	peptidyl-prolyl cis-trans isomerase activity
CA733_RS29155	COG0740	serine-type endopeptidase activity
CA733_RS29160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CA733_RS29170	COG2188	Transcriptional regulator
CA733_RS29175	COG0412	Dienelactone hydrolase
CA733_RS29180	COG0539	negative regulation of cytoplasmic translation
CA733_RS29215	COG0515	serine threonine protein kinase
CA733_RS29215	COG3266	domain, Protein
CA733_RS29250	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CA733_RS29275	COG3118	belongs to the thioredoxin family
CA733_RS29280	COG0516	GMP reductase activity
CA733_RS29285	COG1193	negative regulation of DNA recombination
CA733_RS29295	COG1994	Peptidase M50
CA733_RS29350	COG0666	response to abiotic stimulus
CA733_RS29365	COG0702	epimerase
CA733_RS29390	COG1420	regulation of RNA biosynthetic process
CA733_RS29420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CA733_RS29435	COG1045	serine acetyltransferase
CA733_RS29445	COG0724	RNA recognition motif
CA733_RS29450	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CA733_RS29455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CA733_RS29460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CA733_RS29465	COG3429	Glucose-6-phosphate dehydrogenase subunit
CA733_RS29465	COG3409	Peptidoglycan-binding domain 1 protein
CA733_RS29475	COG1797	cobyrinic acid a,c-diamide synthase activity
CA733_RS29485	COG1615	UPF0182 protein
CA733_RS29525	COG0824	Thioesterase
CA733_RS29550	COG0501	Belongs to the peptidase M48B family
CA733_RS29565	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CA733_RS29570	COG0297	glycogen (starch) synthase activity
CA733_RS29575	COG0181	hydroxymethylbilane synthase activity
CA733_RS29590	COG1597	lipid kinase activity
CA733_RS29590	COG1803	Methylglyoxal synthase
CA733_RS29610	COG0475	glutathione-regulated potassium exporter activity
CA733_RS29620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CA733_RS29660	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CA733_RS29680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CA733_RS29685	COG0719	Fe-S assembly protein
CA733_RS29690	COG0396	ATPase activity
CA733_RS29695	COG0719	Fe-S assembly protein
CA733_RS29715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CA733_RS29735	COG0439	Biotin carboxylase
CA733_RS29750	COG0515	serine threonine protein kinase
CA733_RS29790	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CA733_RS29810	COG4968	Prepilin-type N-terminal cleavage methylation domain
CA733_RS29815	COG0463	Glycosyl transferase, family 2
CA733_RS29820	COG0463	Glycosyl transferase, family 2
CA733_RS29820	COG1216	Glycosyl transferase, family 2
CA733_RS29825	COG1216	Glycosyl transferase, family 2
CA733_RS29825	COG0463	Glycosyl transferase, family 2
CA733_RS29855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CA733_RS29860	COG0552	protein localization to endoplasmic reticulum
CA733_RS29865	COG2208	phosphoserine phosphatase activity
CA733_RS29870	COG5634	Uncharacterized conserved protein (DUF2278)
CA733_RS29885	COG0424	maF-like protein
CA733_RS29915	COG0577	efflux transmembrane transporter activity
CA733_RS29915	COG1136	(ABC) transporter
CA733_RS29930	COG0463	Glycosyl transferase, family 2
CA733_RS29930	COG1216	Glycosyl transferase, family 2
CA733_RS29935	COG0542	response to heat
CA733_RS29945	COG0148	phosphopyruvate hydratase activity
CA733_RS29950	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CA733_RS29955	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CA733_RS29955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CA733_RS29975	COG0170	dolichyl monophosphate biosynthetic process
CA733_RS29980	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CA733_RS29985	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CA733_RS29995	COG1289	transmembrane transporter activity
CA733_RS30020	COG1748	Saccharopine dehydrogenase
CA733_RS30025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA733_RS30030	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CA733_RS30035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CA733_RS30085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA733_RS30100	COG0463	Glycosyl transferase, family 2
CA733_RS30120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CA733_RS30130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CA733_RS30145	COG1027	Aspartate ammonia-lyase
CA733_RS30150	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
CA733_RS30160	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CA733_RS30165	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CA733_RS30175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CA733_RS30180	COG0583	DNA-binding transcription factor activity
CA733_RS30195	COG0723	plastoquinol--plastocyanin reductase activity
CA733_RS30205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS30210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CA733_RS30215	COG1116	anion transmembrane transporter activity
CA733_RS30215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA733_RS30220	COG1116	anion transmembrane transporter activity
CA733_RS30225	COG2223	nitrite transmembrane transporter activity
CA733_RS30230	COG0243	molybdopterin cofactor binding
CA733_RS30290	COG1215	transferase activity, transferring glycosyl groups
CA733_RS30295	COG0793	Belongs to the peptidase S41A family
CA733_RS30320	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CA733_RS30325	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CA733_RS30340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CA733_RS30355	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CA733_RS30360	COG0271	Belongs to the BolA IbaG family
CA733_RS30370	COG4935	Belongs to the peptidase S8 family
CA733_RS30370	COG1404	Belongs to the peptidase S8 family
CA733_RS30380	COG0590	tRNA wobble adenosine to inosine editing
CA733_RS30385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CA733_RS30395	COG1494	fructose-1,6-bisphosphatase
CA733_RS30400	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CA733_RS30410	COG0640	Transcriptional regulator
CA733_RS30445	COG0166	Belongs to the GPI family
CA733_RS30480	COG0039	L-malate dehydrogenase activity
CA733_RS30490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CA733_RS30510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CA733_RS30515	COG0521	Mo-molybdopterin cofactor biosynthetic process
CA733_RS30525	COG1490	D-aminoacyl-tRNA deacylase activity
CA733_RS30535	COG0739	heme binding
CA733_RS30540	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CA733_RS30545	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CA733_RS30575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CA733_RS30675	COG1518	maintenance of DNA repeat elements
CA733_RS30740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CA733_RS30745	COG3150	esterase
CA733_RS30760	COG4251	negative regulation of phosphorylation
CA733_RS30760	COG3706	GGDEF domain
CA733_RS30760	COG2203	Gaf domain
CA733_RS30760	COG5001	Diguanylate cyclase
CA733_RS30800	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CA733_RS30805	COG0594	ribonuclease P activity
CA733_RS30815	COG0706	membrane insertase activity
CA733_RS30830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CA733_RS30845	COG3409	Peptidoglycan-binding domain 1 protein
CA733_RS30845	COG0860	N-Acetylmuramoyl-L-alanine amidase
CA733_RS30850	COG4999	Histidine kinase
CA733_RS30850	COG3850	Histidine kinase
CA733_RS30850	COG3437	response regulator, receiver
CA733_RS30850	COG2205	protein histidine kinase activity
CA733_RS30870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CA733_RS30900	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CA733_RS30905	COG0416	fatty acid biosynthetic process
CA733_RS30910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CA733_RS30915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CA733_RS30920	COG0204	Acyl-transferase
CA733_RS30920	COG0318	PFAM AMP-dependent synthetase and ligase
CA733_RS30925	COG0628	permease
CA733_RS30945	COG1575	Belongs to the MenA family. Type 1 subfamily
CA733_RS30955	COG0318	PFAM AMP-dependent synthetase and ligase
CA733_RS30960	COG0824	Thioesterase
CA733_RS30980	COG3266	domain, Protein
CA733_RS30980	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CA733_RS30985	COG0123	including yeast histone deacetylase and acetoin utilization protein
CA733_RS30995	COG0668	transmembrane transport
CA733_RS31000	COG2911	Protein conserved in bacteria
CA733_RS31000	COG1361	Conserved repeat domain
CA733_RS31000	COG3266	domain, Protein
CA733_RS31135	COG1733	regulation of RNA biosynthetic process
CA733_RS31175	COG0477	Major facilitator Superfamily
CA733_RS31180	COG3659	wide pore channel activity
CA733_RS31185	COG1172	Belongs to the binding-protein-dependent transport system permease family
CA733_RS31190	COG1129	ABC transporter
CA733_RS31195	COG1879	ABC-type sugar transport system periplasmic component
CA733_RS31200	COG1879	ABC-type sugar transport system periplasmic component
CA733_RS31240	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CA733_RS31245	COG1472	Belongs to the glycosyl hydrolase 3 family
CA733_RS31250	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CA733_RS31255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CA733_RS31255	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CA733_RS31260	COG1562	ergosterol biosynthetic process
CA733_RS31290	COG0463	Glycosyl transferase, family 2
CA733_RS31295	COG2814	Major facilitator Superfamily
CA733_RS31305	COG0315	cyclic pyranopterin monophosphate synthase activity
CA733_RS31370	COG5398	heme oxygenase
CA733_RS31375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CA733_RS31390	COG0438	transferase activity, transferring glycosyl groups
CA733_RS31395	COG0438	transferase activity, transferring glycosyl groups
CA733_RS31400	COG0450	alkyl hydroperoxide reductase
CA733_RS31410	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CA733_RS31415	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CA733_RS31425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CA733_RS31455	COG4451	ribulose bisphosphate carboxylase, small
CA733_RS31465	COG1850	ribulose-bisphosphate carboxylase activity
CA733_RS31475	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CA733_RS31520	COG0515	serine threonine protein kinase
CA733_RS31520	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS31525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CA733_RS31530	COG2264	protein methyltransferase activity
CA733_RS31555	COG3118	belongs to the thioredoxin family
CA733_RS31560	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS31570	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CA733_RS31575	COG0459	protein refolding
CA733_RS31580	COG0598	Magnesium transport protein CorA
CA733_RS31595	COG0571	ribonuclease III activity
CA733_RS31605	COG5002	protein histidine kinase activity
CA733_RS31605	COG2205	protein histidine kinase activity
CA733_RS31605	COG0784	Response regulator, receiver
CA733_RS31635	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CA733_RS31645	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CA733_RS31660	COG1132	(ABC) transporter
CA733_RS31670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CA733_RS31690	COG2234	aminopeptidase activity
CA733_RS31710	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CA733_RS31730	COG1834	amidinotransferase
CA733_RS31740	COG2119	membrane
CA733_RS31765	COG1160	GTP binding
CA733_RS31770	COG0149	triose-phosphate isomerase activity
CA733_RS31775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CA733_RS31780	COG0330	HflC and HflK could
CA733_RS31795	COG1131	(ABC) transporter
CA733_RS31800	COG0131	Imidazoleglycerol-phosphate dehydratase
CA733_RS31805	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CA733_RS31810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CA733_RS31815	COG4372	Transposase
CA733_RS31835	COG1185	polyribonucleotide nucleotidyltransferase activity
CA733_RS31845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CA733_RS31850	COG4279	zinc finger
CA733_RS31880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CA733_RS31885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CA733_RS31910	COG3659	wide pore channel activity
CA733_RS31920	COG2132	Multicopper oxidase
CA733_RS31955	COG1366	Belongs to the anti-sigma-factor antagonist family
CA733_RS31965	COG1366	Belongs to the anti-sigma-factor antagonist family
CA733_RS31970	COG2208	phosphoserine phosphatase activity
CA733_RS31970	COG2770	Histidine kinase
CA733_RS31995	COG2211	Major facilitator Superfamily
CA733_RS32000	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CA733_RS32005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CA733_RS32020	COG0515	serine threonine protein kinase
CA733_RS32020	COG3266	domain, Protein
CA733_RS32045	COG0850	regulation of cytokinetic process
CA733_RS32050	COG2894	cell division
CA733_RS32055	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CA733_RS32070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CA733_RS32085	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA733_RS32095	COG0438	transferase activity, transferring glycosyl groups
CA733_RS32110	COG0438	transferase activity, transferring glycosyl groups
CA733_RS32170	COG0604	alcohol dehydrogenase
CA733_RS32170	COG3321	synthase
CA733_RS32170	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS32190	COG0124	histidyl-tRNA synthetase
CA733_RS32210	COG0275	rRNA processing
CA733_RS32215	COG5002	protein histidine kinase activity
CA733_RS32215	COG0784	Response regulator, receiver
CA733_RS32220	COG4172	Belongs to the ABC transporter superfamily
CA733_RS32225	COG0629	single-stranded DNA binding
CA733_RS32235	COG3842	ATPase activity
CA733_RS32255	COG1704	LemA family
CA733_RS32260	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CA733_RS32265	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CA733_RS32280	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA733_RS32305	COG1649	PFAM Uncharacterised BCR, COG1649
CA733_RS32310	COG0737	Belongs to the 5'-nucleotidase family
CA733_RS32330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CA733_RS32350	COG0438	transferase activity, transferring glycosyl groups
CA733_RS32355	COG5002	protein histidine kinase activity
CA733_RS32365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CA733_RS32400	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CA733_RS32405	COG3852	Histidine kinase
CA733_RS32410	COG0628	permease
CA733_RS32415	COG0494	nUDIX hydrolase
CA733_RS32425	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CA733_RS32435	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CA733_RS32455	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CA733_RS32495	COG0586	Pfam SNARE associated Golgi protein
CA733_RS32500	COG2261	transglycosylase associated protein
CA733_RS32560	COG0515	serine threonine protein kinase
CA733_RS32560	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CA733_RS32575	COG0842	Transport permease protein
CA733_RS32575	COG1129	ABC transporter
CA733_RS32580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CA733_RS32590	COG1316	TRANSCRIPTIONal
CA733_RS32595	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS32600	COG0402	S-adenosylhomocysteine deaminase activity
CA733_RS32625	COG2022	thiamine diphosphate biosynthetic process
CA733_RS32625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CA733_RS32635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CA733_RS32665	COG0701	Predicted permease
CA733_RS32670	COG4191	Histidine kinase
CA733_RS32675	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CA733_RS32690	COG0300	oxidoreductase activity
CA733_RS32735	COG1830	Aldolase
CA733_RS32740	COG0318	PFAM AMP-dependent synthetase and ligase
CA733_RS32750	COG2161	toxin-antitoxin pair type II binding
CA733_RS32855	COG0438	transferase activity, transferring glycosyl groups
CA733_RS32860	COG1216	Glycosyl transferase, family 2
CA733_RS32880	COG1215	transferase activity, transferring glycosyl groups
CA733_RS32885	COG1132	(ABC) transporter
CA733_RS32895	COG0489	protein tyrosine kinase activity
CA733_RS32900	COG0438	transferase activity, transferring glycosyl groups
CA733_RS32925	COG1216	Glycosyl transferase, family 2
CA733_RS32930	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CA733_RS32935	COG1442	glycosyl transferase family 8
CA733_RS32940	COG0579	oxidoreductase
CA733_RS32945	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CA733_RS32960	COG4245	von Willebrand factor, type A
CA733_RS32980	COG0784	Response regulator, receiver
CA733_RS32980	COG2205	protein histidine kinase activity
CA733_RS32985	COG1671	Belongs to the UPF0178 family
CA733_RS33005	COG0072	phenylalanine-tRNA ligase activity
CA733_RS33005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CA733_RS33045	COG0789	Transcriptional regulator
CA733_RS33050	COG0484	heat shock protein binding
CA733_RS33125	COG0649	NAD binding
CA733_RS33140	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CA733_RS33175	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CA733_RS33210	COG0492	ferredoxin-NADP+ reductase activity
CA733_RS33235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA733_RS33260	COG0028	Belongs to the TPP enzyme family
CA733_RS33290	COG0515	serine threonine protein kinase
CA733_RS33290	COG3266	domain, Protein
CA733_RS33305	COG5002	protein histidine kinase activity
CA733_RS33310	COG1187	pseudouridine synthase activity
CA733_RS33320	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CA733_RS33340	COG0811	peptide transport
CA733_RS33345	COG0848	biopolymer transport protein
CA733_RS33370	COG0408	coproporphyrinogen oxidase activity
CA733_RS33380	COG0489	protein tyrosine kinase activity
CA733_RS33385	COG0772	Belongs to the SEDS family
CA733_RS33400	COG0475	glutathione-regulated potassium exporter activity
CA733_RS33400	COG0589	response to stress
CA733_RS33405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA733_RS33410	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CA733_RS33435	COG1404	Belongs to the peptidase S8 family
CA733_RS33445	COG0351	phosphomethylpyrimidine kinase
CA733_RS33455	COG0347	Belongs to the P(II) protein family
CA733_RS33460	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CA733_RS33465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CA733_RS33480	COG0586	Pfam SNARE associated Golgi protein
CA733_RS33485	COG0673	inositol 2-dehydrogenase activity
CA733_RS33490	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CA733_RS33495	COG1253	flavin adenine dinucleotide binding
CA733_RS33515	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CA733_RS33520	COG0674	pyruvate-flavodoxin oxidoreductase activity
CA733_RS33520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CA733_RS33520	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CA733_RS33520	COG1013	pyruvate-flavodoxin oxidoreductase activity
CA733_RS33545	COG2319	Wd-40 repeat
CA733_RS33545	COG3903	Transcriptional regulator
CA733_RS33550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CA733_RS33565	COG1333	cytochrome c biogenesis protein
CA733_RS33575	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CA733_RS33630	COG0504	CTP synthase activity
CA733_RS33650	COG0107	imidazoleglycerol-phosphate synthase activity
CA733_RS33655	COG2255	four-way junction helicase activity
CA733_RS33675	COG2124	cytochrome p450
CA733_RS33690	COG0515	serine threonine protein kinase
CA733_RS33700	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CA733_RS33705	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CA733_RS33715	COG2912	Transglutaminase-like superfamily
CA733_RS33725	COG0668	transmembrane transport
CA733_RS33730	COG0628	permease
CA733_RS33750	COG0662	Cupin 2, conserved barrel domain protein
CA733_RS33770	COG4279	zinc finger
CA733_RS33775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CA733_RS33780	COG5002	protein histidine kinase activity
CA733_RS33790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CA733_RS33795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CA733_RS33820	COG0024	Methionine aminopeptidase
CA733_RS33830	COG0612	Peptidase, M16
CA733_RS33860	COG0285	dihydrofolate synthase activity
CA733_RS33905	COG4191	Histidine kinase
CA733_RS33905	COG0784	Response regulator, receiver
CA733_RS33935	COG0515	serine threonine protein kinase
CA733_RS33935	COG2815	serine threonine protein kinase
CA733_RS33940	COG2124	cytochrome p450
CA733_RS33950	COG0702	epimerase
CA733_RS33955	COG0432	Pfam Uncharacterised protein family UPF0047
CA733_RS33965	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CA733_RS33970	COG0745	RESPONSE REGULATOR receiver
CA733_RS33980	COG1809	phosphosulfolactate synthase activity
CA733_RS33990	COG5002	protein histidine kinase activity
CA733_RS34000	COG2208	phosphoserine phosphatase activity
CA733_RS34000	COG2770	Histidine kinase
CA733_RS34015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CA733_RS34035	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CA733_RS34100	COG0556	nucleotide-excision repair
CA733_RS34110	COG3237	CsbD-like
CA733_RS34140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CA733_RS34145	COG1404	Belongs to the peptidase S8 family
CA733_RS34155	COG0628	permease
CA733_RS34165	COG1316	TRANSCRIPTIONal
CA733_RS34175	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CA733_RS34185	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CA733_RS34185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CA733_RS34195	COG1598	PFAM Uncharacterised protein family UPF0150
CA733_RS34210	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS34210	COG0515	serine threonine protein kinase
CA733_RS34225	COG1846	Transcriptional regulator
CA733_RS34245	COG0109	protoheme IX farnesyltransferase activity
CA733_RS34255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CA733_RS34260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CA733_RS34265	COG1845	cytochrome c oxidase, subunit III
CA733_RS34280	COG0515	serine threonine protein kinase
CA733_RS34330	COG1598	PFAM Uncharacterised protein family UPF0150
CA733_RS34340	COG0445	tRNA wobble uridine modification
CA733_RS34365	COG0784	Response regulator, receiver
CA733_RS34365	COG5002	protein histidine kinase activity
CA733_RS34380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CA733_RS34385	COG3621	Patatin-like phospholipase
CA733_RS34390	COG0802	atpase or kinase
CA733_RS34395	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CA733_RS34400	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CA733_RS34420	COG3854	ATPases associated with a variety of cellular activities
CA733_RS34425	COG0725	ABC transporter, periplasmic molybdate-binding protein
CA733_RS34430	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CA733_RS34470	COG1803	Methylglyoxal synthase
CA733_RS34475	COG2954	triphosphatase activity
CA733_RS34480	COG0515	serine threonine protein kinase
CA733_RS34480	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS34510	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
CA733_RS34550	COG3335	DDE superfamily endonuclease
CA733_RS34575	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CA733_RS34575	COG0515	serine threonine protein kinase
CA733_RS34580	COG2442	InterPro IPR007367
CA733_RS34590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CA733_RS34635	COG0375	protein maturation
CA733_RS34740	COG3585	molybdate ion transport
CA733_RS34795	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CA733_RS34805	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CA733_RS34815	COG3266	domain, Protein
CA733_RS34815	COG0515	serine threonine protein kinase
CA733_RS34820	COG0436	Aminotransferase
CA733_RS34825	COG0371	Dehydrogenase
CA733_RS34910	COG2205	protein histidine kinase activity
CA733_RS34910	COG0784	Response regulator, receiver
CA733_RS34910	COG2198	Histidine kinase
CA733_RS34935	COG3781	membrane
CA733_RS34940	COG2234	aminopeptidase activity
CA733_RS34945	COG0443	Heat shock 70 kDa protein
CA733_RS34950	COG0484	heat shock protein binding
CA733_RS34955	COG1074	ATP-dependent DNA helicase activity
CA733_RS34970	COG0025	NhaP-type Na H and K H
CA733_RS34980	COG2204	response regulator
CA733_RS34985	COG2226	methyltransferase
CA733_RS34990	COG4399	Belongs to the UPF0754 family
CA733_RS35005	COG1480	7TM receptor with intracellular HD hydrolase
CA733_RS35020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CA733_RS35025	COG1754	DNA topoisomerase type I activity
CA733_RS35025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CA733_RS35045	COG0724	RNA recognition motif
CA733_RS35070	COG4191	Histidine kinase
CA733_RS35075	COG3706	GGDEF domain
CA733_RS35075	COG2203	Gaf domain
CA733_RS35075	COG5001	Diguanylate cyclase
CA733_RS35075	COG4251	negative regulation of phosphorylation
CA733_RS35095	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CA733_RS35105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CA733_RS35105	COG0475	glutathione-regulated potassium exporter activity
CA733_RS35110	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CA733_RS35115	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CA733_RS35120	COG0126	phosphoglycerate kinase activity
CA733_RS35125	COG0589	response to stress
CA733_RS35130	COG3903	Transcriptional regulator
CA733_RS35130	COG2319	Wd-40 repeat
CA733_RS35155	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CA733_RS35160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CA733_RS35165	COG0784	Response regulator, receiver
CA733_RS35165	COG2205	protein histidine kinase activity
CA733_RS35170	COG0840	transmembrane signaling receptor activity
CA733_RS35170	COG2203	Gaf domain
CA733_RS35180	COG1357	PFAM Pentapeptide repeats (8 copies)
CA733_RS35180	COG0515	serine threonine protein kinase
CA733_RS35190	COG1940	carbohydrate kinase activity
CA733_RS35205	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CA733_RS35210	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CA733_RS35215	COG0435	Glutathione S-transferase
CA733_RS35220	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CA733_RS35225	COG0457	Tetratricopeptide repeat
CA733_RS35230	COG2135	peptidase activity
CA733_RS35235	COG0625	glutathione transferase activity
CA733_RS35240	COG1872	DUF167
CA733_RS35255	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CA733_RS35275	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CA733_RS35280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CA733_RS35285	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CA733_RS35295	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CA733_RS35315	COG0772	Belongs to the SEDS family
CA733_RS35340	COG0438	transferase activity, transferring glycosyl groups
CA733_RS35345	COG0297	glycogen (starch) synthase activity
CA733_RS35375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CA733_RS35390	COG0356	it plays a direct role in the translocation of protons across the membrane
CA733_RS35395	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CA733_RS35400	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CA733_RS35405	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CA733_RS35410	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CA733_RS35415	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CA733_RS35420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CA733_RS35445	COG0018	arginyl-trna synthetase
CA733_RS35450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CA733_RS35460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CA733_RS35470	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CA733_RS35485	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CA733_RS35505	COG1215	transferase activity, transferring glycosyl groups
CA733_RS35515	COG0489	protein tyrosine kinase activity
CA733_RS35520	COG0438	transferase activity, transferring glycosyl groups
CA733_RS35525	COG0438	transferase activity, transferring glycosyl groups
CA733_RS35530	COG5002	protein histidine kinase activity
CA733_RS35545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CA733_RS35565	COG3903	Transcriptional regulator
CA733_RS35565	COG3629	intracellular signal transduction
CA733_RS35570	COG0515	serine threonine protein kinase
CA733_RS35570	COG3266	domain, Protein
CA733_RS35575	COG0515	serine threonine protein kinase
CA733_RS35580	COG0728	peptidoglycan biosynthetic process
CA733_RS35590	COG2197	response regulator
CA733_RS35595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA733_RS35605	COG5001	Diguanylate cyclase
CA733_RS35605	COG2203	Gaf domain
CA733_RS35605	COG3706	GGDEF domain
CA733_RS35605	COG4251	negative regulation of phosphorylation
CA733_RS35610	COG1672	PFAM Archaeal ATPase
CA733_RS35610	COG2319	Wd-40 repeat
CA733_RS35670	COG0561	phosphatase activity
CA733_RS35675	COG0632	four-way junction helicase activity
CA733_RS35680	COG0156	8-amino-7-oxononanoate synthase activity
CA733_RS35690	COG0515	serine threonine protein kinase
CA733_RS35710	COG3335	DDE superfamily endonuclease
CA733_RS35720	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CA733_RS35730	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CA733_RS35755	COG4191	Histidine kinase
CA733_RS35765	COG0297	glycogen (starch) synthase activity
CA733_RS35780	COG0697	spore germination
CA733_RS35845	COG1192	Involved in chromosome partitioning
CA733_RS35855	COG0328	RNA-DNA hybrid ribonuclease activity
CA733_RS35895	COG1475	DNA binding
CA733_RS35905	COG0724	RNA recognition motif
CA733_RS35910	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CA733_RS35945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CA733_RS36000	COG1028	Short-chain dehydrogenase reductase Sdr
CA733_RS36015	COG5433	transposase activity
CA733_RS36035	COG0418	dihydroorotase activity
CA733_RS36060	COG4644	lycopene metabolic process
CA733_RS36070	COG0582	viral genome integration into host DNA
CA733_RS36080	COG0277	FAD linked oxidase domain protein
CA733_RS36085	COG2124	cytochrome p450
CA733_RS36195	COG1674	ftsk spoiiie
CA733_RS36225	COG0582	viral genome integration into host DNA
CA733_RS36280	COG4974	Belongs to the 'phage' integrase family
CA733_RS36450	COG0464	growth
CA733_RS36470	COG5433	transposase activity
CA733_RS36480	COG1032	radical SAM domain protein
CA733_RS36565	COG5433	transposase activity
CA733_RS36655	COG0546	phosphoglycolate phosphatase activity
CA733_RS36660	COG0758	DNA mediated transformation
CA733_RS36665	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CA733_RS36730	COG0667	Aldo Keto reductase
CA733_RS36735	COG0667	Aldo Keto reductase
CA733_RS36760	COG3335	DDE superfamily endonuclease
CA733_RS36875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CA733_RS36905	COG1192	Involved in chromosome partitioning