locus-tag	class	description
CBLAS_RS00015	COG0592	DNA-directed DNA polymerase activity
CBLAS_RS00020	COG0187	DNA topoisomerase II activity
CBLAS_RS00025	COG2199	diguanylate cyclase activity
CBLAS_RS00025	COG2200	EAL domain
CBLAS_RS00025	COG3287	FIST C domain
CBLAS_RS00055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CBLAS_RS00080	COG0748	coenzyme F420 binding
CBLAS_RS00125	COG0842	Transport permease protein
CBLAS_RS00130	COG0842	Transport permease protein
CBLAS_RS00135	COG1131	(ABC) transporter
CBLAS_RS00150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBLAS_RS00165	COG0513	Belongs to the DEAD box helicase family
CBLAS_RS00170	COG2860	membrane
CBLAS_RS00175	COG0642	Histidine kinase
CBLAS_RS00180	COG0745	RESPONSE REGULATOR receiver
CBLAS_RS00190	COG1704	LemA family
CBLAS_RS00205	COG1294	oxidase, subunit
CBLAS_RS00210	COG1271	oxidase subunit
CBLAS_RS00220	COG0504	CTP synthase activity
CBLAS_RS00225	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CBLAS_RS00225	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CBLAS_RS00240	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CBLAS_RS00245	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CBLAS_RS00275	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CBLAS_RS00280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CBLAS_RS00285	COG0564	pseudouridine synthase activity
CBLAS_RS00295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CBLAS_RS00305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CBLAS_RS00315	COG0517	IMP dehydrogenase activity
CBLAS_RS00315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CBLAS_RS00320	COG1187	pseudouridine synthase activity
CBLAS_RS00325	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CBLAS_RS00330	COG1518	maintenance of DNA repeat elements
CBLAS_RS00335	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CBLAS_RS00360	COG0803	Belongs to the bacterial solute-binding protein 9 family
CBLAS_RS00370	COG1121	(ABC) transporter
CBLAS_RS00375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CBLAS_RS00385	COG2814	Major facilitator Superfamily
CBLAS_RS00400	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CBLAS_RS00410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CBLAS_RS00420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CBLAS_RS00435	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CBLAS_RS00440	COG0237	dephospho-CoA kinase activity
CBLAS_RS00445	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CBLAS_RS00455	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CBLAS_RS00455	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CBLAS_RS00460	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CBLAS_RS00465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CBLAS_RS00470	COG0243	molybdopterin cofactor binding
CBLAS_RS00475	COG0437	4 iron, 4 sulfur cluster binding
CBLAS_RS00490	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CBLAS_RS00495	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CBLAS_RS00510	COG3133	Outer membrane lipoprotein
CBLAS_RS00530	COG0310	cobalt ion transport
CBLAS_RS00535	COG0501	Belongs to the peptidase M48B family
CBLAS_RS00545	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CBLAS_RS00570	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CBLAS_RS00585	COG0778	Nitroreductase
CBLAS_RS00590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBLAS_RS00595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBLAS_RS00600	COG0754	glutathionylspermidine amidase activity
CBLAS_RS00615	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CBLAS_RS00635	COG1538	Outer membrane efflux protein
CBLAS_RS00650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBLAS_RS00655	COG1120	ATPase activity
CBLAS_RS00675	COG0544	peptidyl-prolyl cis-trans isomerase activity
CBLAS_RS00680	COG0740	serine-type endopeptidase activity
CBLAS_RS00685	COG0242	peptide deformylase activity
CBLAS_RS00690	COG0606	chelatase, subunit chli
CBLAS_RS00695	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CBLAS_RS00695	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CBLAS_RS00700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CBLAS_RS00705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBLAS_RS00720	COG0861	Integral membrane protein TerC family
CBLAS_RS00735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CBLAS_RS00770	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBLAS_RS00775	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBLAS_RS00780	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBLAS_RS00785	COG0649	NAD binding
CBLAS_RS00805	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CBLAS_RS00810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBLAS_RS00815	COG0839	Belongs to the complex I subunit 6 family
CBLAS_RS00825	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CBLAS_RS00830	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBLAS_RS00835	COG1007	ATP synthesis coupled electron transport
CBLAS_RS00840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CBLAS_RS00850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CBLAS_RS00855	COG0602	queuosine metabolic process
CBLAS_RS00875	COG0254	rRNA binding
CBLAS_RS00880	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CBLAS_RS00900	COG0436	Aminotransferase
CBLAS_RS00905	COG0460	homoserine dehydrogenase
CBLAS_RS00910	COG0792	nuclease activity
CBLAS_RS00915	COG3118	belongs to the thioredoxin family
CBLAS_RS00920	COG0492	ferredoxin-NADP+ reductase activity
CBLAS_RS00930	COG0243	molybdopterin cofactor binding
CBLAS_RS00935	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CBLAS_RS00940	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CBLAS_RS00950	COG0247	lactate metabolic process
CBLAS_RS00955	COG1139	Iron-sulfur cluster binding protein
CBLAS_RS00965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CBLAS_RS00965	COG0140	phosphoribosyl-ATP diphosphatase activity
CBLAS_RS00970	COG0330	HflC and HflK could
CBLAS_RS01000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CBLAS_RS01005	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CBLAS_RS01010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CBLAS_RS01020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CBLAS_RS01035	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CBLAS_RS01040	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBLAS_RS01045	COG1129	ABC transporter
CBLAS_RS01090	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CBLAS_RS01095	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CBLAS_RS01100	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBLAS_RS01105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CBLAS_RS01130	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CBLAS_RS01135	COG0193	aminoacyl-tRNA hydrolase activity
CBLAS_RS01145	COG0019	diaminopimelate decarboxylase activity
CBLAS_RS01160	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CBLAS_RS01165	COG0735	belongs to the Fur family
CBLAS_RS01180	COG1570	exodeoxyribonuclease VII activity
CBLAS_RS01190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBLAS_RS01195	COG0416	fatty acid biosynthetic process
CBLAS_RS01200	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CBLAS_RS01210	COG0105	UTP biosynthetic process
CBLAS_RS01220	COG0450	alkyl hydroperoxide reductase
CBLAS_RS01230	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CBLAS_RS01240	COG0745	RESPONSE REGULATOR receiver
CBLAS_RS01245	COG0642	Histidine kinase
CBLAS_RS01250	COG0248	Ppx GppA phosphatase
CBLAS_RS01265	COG1592	Rubrerythrin
CBLAS_RS01280	COG0204	Acyl-transferase
CBLAS_RS01280	COG0318	PFAM AMP-dependent synthetase and ligase
CBLAS_RS01285	COG1114	Component of the transport system for branched-chain amino acids
CBLAS_RS01300	COG0640	Transcriptional regulator
CBLAS_RS01305	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CBLAS_RS01310	COG1687	branched-chain amino acid
CBLAS_RS01325	COG3005	denitrification pathway
CBLAS_RS01335	COG3976	FMN-binding domain protein
CBLAS_RS01335	COG1053	succinate dehydrogenase
CBLAS_RS01340	COG1053	succinate dehydrogenase
CBLAS_RS01345	COG1053	succinate dehydrogenase
CBLAS_RS01345	COG3976	FMN-binding domain protein
CBLAS_RS01350	COG0583	DNA-binding transcription factor activity
CBLAS_RS01355	COG4206	TonB-dependent receptor
CBLAS_RS01355	COG1629	transport
CBLAS_RS01360	COG1053	succinate dehydrogenase
CBLAS_RS01375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CBLAS_RS01390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CBLAS_RS01395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CBLAS_RS01405	COG2863	cytochrome
CBLAS_RS01420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CBLAS_RS01425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CBLAS_RS01430	COG0195	Participates in both transcription termination and antitermination
CBLAS_RS01440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBLAS_RS01445	COG2121	Domain of unknown function (DUF374)
CBLAS_RS01500	COG0725	ABC transporter, periplasmic molybdate-binding protein
CBLAS_RS01515	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CBLAS_RS01525	COG4208	sulfate ABC transporter
CBLAS_RS01530	COG0157	Belongs to the NadC ModD family
CBLAS_RS01550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBLAS_RS01555	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CBLAS_RS01560	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CBLAS_RS01575	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CBLAS_RS01585	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CBLAS_RS01590	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CBLAS_RS01610	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBLAS_RS01635	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CBLAS_RS01640	COG0583	DNA-binding transcription factor activity
CBLAS_RS01645	COG2855	membrane
CBLAS_RS01650	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CBLAS_RS01655	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CBLAS_RS01660	COG0126	phosphoglycerate kinase activity
CBLAS_RS01665	COG0149	triose-phosphate isomerase activity
CBLAS_RS01675	COG1793	dna ligase
CBLAS_RS01690	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CBLAS_RS01695	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CBLAS_RS01700	COG2264	protein methyltransferase activity
CBLAS_RS01705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBLAS_RS01710	COG1183	phosphatidylcholine synthase activity
CBLAS_RS01715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBLAS_RS01720	COG0385	Bile acid
CBLAS_RS01725	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CBLAS_RS01740	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CBLAS_RS01745	COG1160	GTP binding
CBLAS_RS01750	COG0697	spore germination
CBLAS_RS01760	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CBLAS_RS01765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBLAS_RS01825	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CBLAS_RS01875	COG3646	Phage regulatory protein
CBLAS_RS01910	COG0569	domain protein
CBLAS_RS01915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CBLAS_RS01925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CBLAS_RS01935	COG0693	protein deglycase activity
CBLAS_RS01945	COG0587	DNA-directed DNA polymerase activity
CBLAS_RS01960	COG1968	undecaprenyl-diphosphatase activity
CBLAS_RS01965	COG0352	thiamine-phosphate diphosphorylase activity
CBLAS_RS01985	COG0765	amino acid transport
CBLAS_RS01990	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CBLAS_RS01995	COG0243	molybdopterin cofactor binding
CBLAS_RS02000	COG0437	4 iron, 4 sulfur cluster binding
CBLAS_RS02005	COG0348	domain, Protein
CBLAS_RS02010	COG3043	anaerobic respiration
CBLAS_RS02030	COG4773	Receptor
CBLAS_RS02040	COG0723	plastoquinol--plastocyanin reductase activity
CBLAS_RS02060	COG0445	tRNA wobble uridine modification
CBLAS_RS02065	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CBLAS_RS02080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CBLAS_RS02085	COG0052	Belongs to the universal ribosomal protein uS2 family
CBLAS_RS02090	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CBLAS_RS02095	COG1136	(ABC) transporter
CBLAS_RS02110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CBLAS_RS02135	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CBLAS_RS02140	COG0113	porphobilinogen synthase activity
CBLAS_RS02155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBLAS_RS02160	COG0247	lactate metabolic process
CBLAS_RS02195	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CBLAS_RS02200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CBLAS_RS02215	COG0250	Participates in transcription elongation, termination and antitermination
CBLAS_RS02220	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CBLAS_RS02225	COG0081	regulation of translation
CBLAS_RS02230	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CBLAS_RS02235	COG0222	ribosome binding
CBLAS_RS02240	COG0085	RNA polymerase activity
CBLAS_RS02245	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CBLAS_RS02250	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CBLAS_RS02255	COG0049	tRNA binding
CBLAS_RS02260	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CBLAS_RS02280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CBLAS_RS02285	COG1252	NADH dehydrogenase
CBLAS_RS02295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CBLAS_RS02300	COG0733	neurotransmitter:sodium symporter activity
CBLAS_RS02305	COG1607	acyl-coa hydrolase
CBLAS_RS02310	COG1546	Belongs to the CinA family
CBLAS_RS02310	COG1058	Belongs to the CinA family
CBLAS_RS02315	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CBLAS_RS02320	COG0154	amidase activity
CBLAS_RS02325	COG0517	IMP dehydrogenase activity
CBLAS_RS02325	COG0516	GMP reductase activity
CBLAS_RS02330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CBLAS_RS02335	COG1722	exodeoxyribonuclease VII activity
CBLAS_RS02345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CBLAS_RS02350	COG0519	Catalyzes the synthesis of GMP from XMP
CBLAS_RS02365	COG1193	negative regulation of DNA recombination
CBLAS_RS02380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBLAS_RS02405	COG0251	oxidation-reduction process
CBLAS_RS02410	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CBLAS_RS02470	COG0579	oxidoreductase
CBLAS_RS02480	COG0469	pyruvate kinase activity
CBLAS_RS02490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBLAS_RS02495	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CBLAS_RS02500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CBLAS_RS02505	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CBLAS_RS02510	COG0642	Histidine kinase
CBLAS_RS02515	COG0745	RESPONSE REGULATOR receiver
CBLAS_RS02520	COG0484	heat shock protein binding
CBLAS_RS02550	COG0519	Catalyzes the synthesis of GMP from XMP
CBLAS_RS02570	COG1715	Restriction endonuclease
CBLAS_RS02590	COG1125	glycine betaine transport
CBLAS_RS02590	COG0517	IMP dehydrogenase activity
CBLAS_RS02595	COG1174	glycine betaine transport
CBLAS_RS02605	COG1174	glycine betaine transport
CBLAS_RS02615	COG0732	type I restriction modification DNA specificity domain
CBLAS_RS02665	COG1185	polyribonucleotide nucleotidyltransferase activity
CBLAS_RS02685	COG0165	Argininosuccinate lyase
CBLAS_RS02695	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CBLAS_RS02700	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CBLAS_RS02710	COG0537	adenosine 5'-monophosphoramidase activity
CBLAS_RS02715	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CBLAS_RS02725	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CBLAS_RS02730	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CBLAS_RS02735	COG0539	negative regulation of cytoplasmic translation
CBLAS_RS02735	COG1185	polyribonucleotide nucleotidyltransferase activity
CBLAS_RS02740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBLAS_RS02755	COG0612	Peptidase, M16
CBLAS_RS02770	COG1012	belongs to the aldehyde dehydrogenase family
CBLAS_RS02810	COG1823	symporter activity
CBLAS_RS02830	COG0174	glutamine synthetase
CBLAS_RS02840	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CBLAS_RS02845	COG0752	glycyl-tRNA synthetase alpha subunit
CBLAS_RS02850	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CBLAS_RS02860	COG1519	Transferase
CBLAS_RS02865	COG0564	pseudouridine synthase activity
CBLAS_RS02870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CBLAS_RS02875	COG0228	four-way junction DNA binding
CBLAS_RS02885	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CBLAS_RS02895	COG0335	large ribosomal subunit rRNA binding
CBLAS_RS02900	COG0714	Associated with various cellular activities
CBLAS_RS02965	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CBLAS_RS02975	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CBLAS_RS02980	COG0768	penicillin binding
CBLAS_RS02990	COG1333	cytochrome c biogenesis protein
CBLAS_RS02990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CBLAS_RS03000	COG0484	heat shock protein binding
CBLAS_RS03035	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CBLAS_RS03060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CBLAS_RS03065	COG0210	DNA helicase
CBLAS_RS03080	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CBLAS_RS03085	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CBLAS_RS03090	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CBLAS_RS03095	COG1862	Preprotein translocase
CBLAS_RS03100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBLAS_RS03105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBLAS_RS03125	COG0285	dihydrofolate synthase activity
CBLAS_RS03130	COG0739	heme binding
CBLAS_RS03135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CBLAS_RS03150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CBLAS_RS03155	COG2176	DNA-directed DNA polymerase activity
CBLAS_RS03160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CBLAS_RS03165	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CBLAS_RS03185	COG0840	transmembrane signaling receptor activity
CBLAS_RS03190	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CBLAS_RS03195	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBLAS_RS03235	COG0629	single-stranded DNA binding
CBLAS_RS03240	COG0360	Binds together with S18 to 16S ribosomal RNA
CBLAS_RS03250	COG0557	exoribonuclease II activity
CBLAS_RS03260	COG2861	carbohydrate metabolic process
CBLAS_RS03265	COG0758	DNA mediated transformation
CBLAS_RS03270	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CBLAS_RS03280	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CBLAS_RS03285	COG0805	protein transport
CBLAS_RS03290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CBLAS_RS03295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBLAS_RS03300	COG0494	nUDIX hydrolase
CBLAS_RS03305	COG0527	aspartate kinase activity
CBLAS_RS03320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CBLAS_RS03325	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CBLAS_RS03340	COG0196	riboflavin kinase activity
CBLAS_RS03345	COG2226	methyltransferase
CBLAS_RS03355	COG1959	2 iron, 2 sulfur cluster binding
CBLAS_RS03375	COG1420	regulation of RNA biosynthetic process
CBLAS_RS03380	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CBLAS_RS03385	COG0443	Heat shock 70 kDa protein
CBLAS_RS03430	COG0753	catalase activity
CBLAS_RS03445	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CBLAS_RS03450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CBLAS_RS03460	COG1663	tetraacyldisaccharide 4'-kinase activity
CBLAS_RS03470	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CBLAS_RS03475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CBLAS_RS03485	COG2195	Cleaves the N-terminal amino acid of tripeptides
CBLAS_RS03490	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CBLAS_RS03495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBLAS_RS03500	COG0191	fructose-bisphosphate aldolase activity
CBLAS_RS03520	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CBLAS_RS03530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CBLAS_RS03540	COG0066	3-isopropylmalate dehydratase activity
CBLAS_RS03545	COG0473	3-isopropylmalate dehydrogenase activity
CBLAS_RS03560	COG0517	IMP dehydrogenase activity
CBLAS_RS03560	COG0617	tRNA 3'-terminal CCA addition
CBLAS_RS03560	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CBLAS_RS03575	COG0788	formyltetrahydrofolate deformylase activity
CBLAS_RS03580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CBLAS_RS03595	COG0751	glycine-tRNA ligase activity
CBLAS_RS03600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CBLAS_RS03605	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CBLAS_RS03630	COG0367	asparagine synthase
CBLAS_RS03670	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CBLAS_RS03675	COG1215	transferase activity, transferring glycosyl groups
CBLAS_RS03680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBLAS_RS03690	COG0739	heme binding
CBLAS_RS03715	COG0730	response to heat
CBLAS_RS03720	COG0356	it plays a direct role in the translocation of protons across the membrane
CBLAS_RS03725	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBLAS_RS03740	COG2962	Rard protein
CBLAS_RS03745	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CBLAS_RS03750	COG1301	dicarboxylic acid transport
CBLAS_RS03755	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CBLAS_RS03760	COG0217	transcriptional regulatory protein
CBLAS_RS03770	COG2217	Heavy metal translocating P-type atpase
CBLAS_RS03780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBLAS_RS03785	COG1049	propionate catabolic process, 2-methylcitrate cycle
CBLAS_RS03795	COG4221	oxidoreductase activity
CBLAS_RS03800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CBLAS_RS03810	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CBLAS_RS03820	COG0101	tRNA pseudouridine synthase activity
CBLAS_RS03830	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CBLAS_RS03835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CBLAS_RS03845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CBLAS_RS03855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBLAS_RS03860	COG1136	(ABC) transporter
CBLAS_RS03860	COG0577	efflux transmembrane transporter activity
CBLAS_RS03865	COG1538	Outer membrane efflux protein
CBLAS_RS03870	COG0343	queuine tRNA-ribosyltransferase activity
CBLAS_RS03880	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CBLAS_RS03890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBLAS_RS03895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBLAS_RS03900	COG0521	Mo-molybdopterin cofactor biosynthetic process
CBLAS_RS03910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBLAS_RS03915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CBLAS_RS03920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CBLAS_RS03920	COG0512	Glutamine amidotransferase of anthranilate synthase
CBLAS_RS03925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CBLAS_RS03935	COG0133	tryptophan synthase activity
CBLAS_RS03945	COG2353	YceI-like domain
CBLAS_RS03950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBLAS_RS03955	COG3021	interspecies interaction between organisms
CBLAS_RS03990	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CBLAS_RS04015	COG0776	regulation of translation
CBLAS_RS04020	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CBLAS_RS04020	COG4797	methyltransferase
CBLAS_RS04025	COG3022	response to hydroperoxide
CBLAS_RS04050	COG2824	Alkylphosphonate utilization operon protein PhnA
CBLAS_RS04085	COG1137	ATPase activity
CBLAS_RS04095	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CBLAS_RS04100	COG0137	argininosuccinate synthase activity
CBLAS_RS04105	COG0359	binds to the 23S rRNA
CBLAS_RS04110	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CBLAS_RS04120	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CBLAS_RS04170	COG1674	ftsk spoiiie
CBLAS_RS04170	COG1196	nuclear chromosome segregation
CBLAS_RS04175	COG0772	Belongs to the SEDS family
CBLAS_RS04180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CBLAS_RS04275	COG1151	hydroxylamine reductase activity
CBLAS_RS04280	COG0582	viral genome integration into host DNA
CBLAS_RS04290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CBLAS_RS04300	COG0045	succinate-CoA ligase (ADP-forming) activity
CBLAS_RS04305	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CBLAS_RS04315	COG0674	pyruvate-flavodoxin oxidoreductase activity
CBLAS_RS04315	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CBLAS_RS04320	COG3962	Belongs to the TPP enzyme family
CBLAS_RS04330	COG0716	FMN binding
CBLAS_RS04350	COG3177	Filamentation induced by cAMP protein fic
CBLAS_RS04370	COG3550	peptidyl-serine autophosphorylation
CBLAS_RS04375	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CBLAS_RS04380	COG0750	zinc metalloprotease
CBLAS_RS04390	COG1028	Short-chain dehydrogenase reductase Sdr
CBLAS_RS04395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBLAS_RS04400	COG0612	Peptidase, M16
CBLAS_RS04405	COG1132	(ABC) transporter
CBLAS_RS04410	COG0215	cysteine-tRNA ligase activity
CBLAS_RS04415	COG0728	peptidoglycan biosynthetic process
CBLAS_RS04420	COG0632	four-way junction helicase activity
CBLAS_RS04425	COG1181	Belongs to the D-alanine--D-alanine ligase family
CBLAS_RS04440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CBLAS_RS04465	COG0280	phosphate acetyltransferase
CBLAS_RS04475	COG0028	Belongs to the TPP enzyme family
CBLAS_RS04480	COG0440	acetolactate synthase activity
CBLAS_RS04485	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBLAS_RS04500	COG0586	Pfam SNARE associated Golgi protein
CBLAS_RS04520	COG2842	Transposition protein
CBLAS_RS04605	COG3646	Phage regulatory protein
CBLAS_RS04670	COG3392	D12 class N6 adenine-specific DNA methyltransferase
CBLAS_RS04780	COG1464	Belongs to the NlpA lipoprotein family
CBLAS_RS04785	COG2011	ABC-type metal ion transport system permease component
CBLAS_RS04790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CBLAS_RS04805	COG4953	penicillin-binding protein 1C
CBLAS_RS04820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBLAS_RS04825	COG0114	fumarate hydratase activity
CBLAS_RS04855	COG0326	Molecular chaperone. Has ATPase activity
CBLAS_RS04865	COG0047	phosphoribosylformylglycinamidine synthase activity
CBLAS_RS04870	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CBLAS_RS04875	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CBLAS_RS04880	COG0793	Belongs to the peptidase S41A family
CBLAS_RS04885	COG0542	response to heat
CBLAS_RS04890	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CBLAS_RS04895	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CBLAS_RS04900	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CBLAS_RS04905	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CBLAS_RS04915	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CBLAS_RS04920	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CBLAS_RS04925	COG0298	carbon dioxide binding
CBLAS_RS04930	COG0409	Hydrogenase expression formation protein
CBLAS_RS04935	COG0309	Hydrogenase expression formation protein (HypE)
CBLAS_RS04940	COG0375	protein maturation
CBLAS_RS04960	COG0446	pyridine nucleotide-disulphide oxidoreductase
CBLAS_RS04970	COG2833	Protein of unknown function (DUF455)
CBLAS_RS04985	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CBLAS_RS04990	COG0303	'Molybdopterin
CBLAS_RS05000	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CBLAS_RS05005	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CBLAS_RS05010	COG0124	histidyl-tRNA synthetase
CBLAS_RS05015	COG1166	arginine decarboxylase activity
CBLAS_RS05020	COG1045	serine acetyltransferase
CBLAS_RS05025	COG0436	Aminotransferase
CBLAS_RS05030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CBLAS_RS05035	COG1335	isochorismatase
CBLAS_RS05045	COG1228	amidohydrolase
CBLAS_RS05055	COG0772	Belongs to the SEDS family
CBLAS_RS05105	COG2252	PERMEase
CBLAS_RS05110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CBLAS_RS05125	COG3842	ATPase activity
CBLAS_RS05135	COG1840	ABC-type Fe3 transport system, periplasmic component
CBLAS_RS05150	COG1304	FMN binding
CBLAS_RS05160	COG5002	protein histidine kinase activity
CBLAS_RS05165	COG0745	RESPONSE REGULATOR receiver
CBLAS_RS05170	COG3301	Polysulphide reductase, NrfD
CBLAS_RS05175	COG0437	4 iron, 4 sulfur cluster binding
CBLAS_RS05180	COG0243	molybdopterin cofactor binding
CBLAS_RS05185	COG0778	Nitroreductase
CBLAS_RS05195	COG1741	Belongs to the pirin family
CBLAS_RS05230	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CBLAS_RS05250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBLAS_RS05275	COG3550	peptidyl-serine autophosphorylation
CBLAS_RS05340	COG2255	four-way junction helicase activity
CBLAS_RS05345	COG0628	permease
CBLAS_RS05360	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CBLAS_RS05365	COG1053	succinate dehydrogenase
CBLAS_RS05375	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CBLAS_RS05385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CBLAS_RS05405	COG0134	indole-3-glycerol-phosphate synthase activity
CBLAS_RS05420	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CBLAS_RS05430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CBLAS_RS05440	COG0243	molybdopterin cofactor binding
CBLAS_RS05500	COG0181	hydroxymethylbilane synthase activity
CBLAS_RS05510	COG0442	prolyl-tRNA aminoacylation
CBLAS_RS05520	COG0142	geranyltranstransferase activity
CBLAS_RS05530	COG0546	phosphoglycolate phosphatase activity
CBLAS_RS05535	COG0318	PFAM AMP-dependent synthetase and ligase
CBLAS_RS05540	COG4948	Mandelate Racemase Muconate Lactonizing
CBLAS_RS05545	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CBLAS_RS05550	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CBLAS_RS05565	COG1794	racemase activity, acting on amino acids and derivatives
CBLAS_RS05575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CBLAS_RS05580	COG0733	neurotransmitter:sodium symporter activity
CBLAS_RS05585	COG0733	neurotransmitter:sodium symporter activity
CBLAS_RS05590	COG3263	regulation of cellular component size
CBLAS_RS05600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CBLAS_RS05600	COG0475	glutathione-regulated potassium exporter activity
CBLAS_RS05605	COG0789	Transcriptional regulator
CBLAS_RS05610	COG0484	heat shock protein binding
CBLAS_RS05620	COG0745	RESPONSE REGULATOR receiver
CBLAS_RS05625	COG0642	Histidine kinase
CBLAS_RS05635	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CBLAS_RS05640	COG4591	ABC-type transport system involved in lipoprotein release permease component
CBLAS_RS05645	COG0653	protein targeting
CBLAS_RS05650	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CBLAS_RS05655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CBLAS_RS05685	COG0275	rRNA processing
CBLAS_RS05700	COG0849	cell division
CBLAS_RS05710	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CBLAS_RS05720	COG0138	bifunctional purine biosynthesis protein purh
CBLAS_RS05735	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CBLAS_RS05740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CBLAS_RS05745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CBLAS_RS05750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CBLAS_RS05755	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CBLAS_RS05765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CBLAS_RS05770	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CBLAS_RS05785	COG0438	transferase activity, transferring glycosyl groups
CBLAS_RS05790	COG0859	PFAM glycosyl transferase family 9
CBLAS_RS05795	COG0463	Glycosyl transferase, family 2
CBLAS_RS05820	COG1560	Kdo2-lipid A biosynthetic process
CBLAS_RS05835	COG0706	membrane insertase activity
CBLAS_RS05845	COG0594	ribonuclease P activity
CBLAS_RS05850	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CBLAS_RS05865	COG0824	Thioesterase
CBLAS_RS05880	COG2890	protein-(glutamine-N5) methyltransferase activity
CBLAS_RS05885	COG0501	Belongs to the peptidase M48B family
CBLAS_RS05890	COG1090	epimerase
CBLAS_RS05895	COG1757	Na H antiporter
CBLAS_RS05915	COG5295	Hep Hag repeat protein
CBLAS_RS05915	COG5295	Hep Hag repeat protein
CBLAS_RS05940	COG0534	Mate efflux family protein
CBLAS_RS05965	COG2957	Belongs to the agmatine deiminase family
CBLAS_RS05975	COG0305	Participates in initiation and elongation during chromosome replication
CBLAS_RS05980	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CBLAS_RS05985	COG0351	phosphomethylpyrimidine kinase
CBLAS_RS06010	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CBLAS_RS06015	COG4771	TonB-dependent receptor
CBLAS_RS06020	COG0811	peptide transport
CBLAS_RS06025	COG0848	biopolymer transport protein
CBLAS_RS06040	COG0494	nUDIX hydrolase
CBLAS_RS06050	COG0741	lytic transglycosylase activity
CBLAS_RS06050	COG1196	nuclear chromosome segregation
CBLAS_RS06050	COG0739	heme binding
CBLAS_RS06060	COG0277	FAD linked oxidase domain protein
CBLAS_RS06065	COG1295	ribonuclease BN
CBLAS_RS06070	COG0543	2 iron, 2 sulfur cluster binding
CBLAS_RS06075	COG0167	dihydroorotate dehydrogenase activity
CBLAS_RS06080	COG0284	orotidine-5'-phosphate decarboxylase activity
CBLAS_RS06085	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CBLAS_RS06110	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CBLAS_RS06125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CBLAS_RS06130	COG0612	Peptidase, M16
CBLAS_RS06165	COG0745	RESPONSE REGULATOR receiver
CBLAS_RS06185	COG1053	succinate dehydrogenase
CBLAS_RS06185	COG3976	FMN-binding domain protein
CBLAS_RS06190	COG2986	histidine ammonia-lyase
CBLAS_RS06220	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CBLAS_RS06230	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CBLAS_RS06235	COG0681	Belongs to the peptidase S26 family
CBLAS_RS06240	COG0698	ribose 5-phosphate isomerase
CBLAS_RS06245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBLAS_RS06255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CBLAS_RS06260	COG0012	GTP binding
CBLAS_RS06270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBLAS_RS06270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBLAS_RS06280	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CBLAS_RS06305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBLAS_RS06310	COG1970	mechanosensitive ion channel activity
CBLAS_RS06320	COG1408	metallophosphoesterase
CBLAS_RS06325	COG0688	phosphatidylethanolamine metabolic process
CBLAS_RS06340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CBLAS_RS06345	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CBLAS_RS06350	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CBLAS_RS06365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CBLAS_RS06380	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CBLAS_RS06385	COG0131	Imidazoleglycerol-phosphate dehydratase
CBLAS_RS06390	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CBLAS_RS06400	COG0084	hydrolase, TatD family'
CBLAS_RS06405	COG0497	DNA recombination
CBLAS_RS06415	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CBLAS_RS06420	COG0563	adenylate kinase activity
CBLAS_RS06425	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CBLAS_RS06455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBLAS_RS06455	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CBLAS_RS06465	COG2070	2-Nitropropane dioxygenase
CBLAS_RS06475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CBLAS_RS06480	COG1758	RNA polymerase activity
CBLAS_RS06485	COG0528	UMP kinase activity
CBLAS_RS06500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CBLAS_RS06505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CBLAS_RS06515	COG0564	pseudouridine synthase activity
CBLAS_RS06520	COG0772	Belongs to the SEDS family
CBLAS_RS06585	COG1418	mRNA catabolic process
CBLAS_RS06600	COG0552	protein localization to endoplasmic reticulum
CBLAS_RS06605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CBLAS_RS06625	COG0783	Belongs to the Dps family
CBLAS_RS06630	COG0166	Belongs to the GPI family
CBLAS_RS06640	COG3839	Belongs to the ABC transporter superfamily
CBLAS_RS06645	COG4662	Binding-protein-dependent transport system inner membrane component
CBLAS_RS06650	COG2998	abc-type tungstate transport system, permease component
CBLAS_RS06655	COG1739	Uncharacterized protein family UPF0029
CBLAS_RS06670	COG2022	thiamine diphosphate biosynthetic process
CBLAS_RS06675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CBLAS_RS06685	COG0488	(ABC) transporter
CBLAS_RS06690	COG2171	N-acyltransferase activity
CBLAS_RS06695	COG0489	protein tyrosine kinase activity
CBLAS_RS06715	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CBLAS_RS06720	COG0848	biopolymer transport protein
CBLAS_RS06725	COG0811	peptide transport
CBLAS_RS06735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CBLAS_RS06735	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CBLAS_RS06740	COG0745	RESPONSE REGULATOR receiver
CBLAS_RS06750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CBLAS_RS06765	COG0556	nucleotide-excision repair
CBLAS_RS06770	COG0640	Transcriptional regulator
CBLAS_RS06775	COG2217	Heavy metal translocating P-type atpase
CBLAS_RS06795	COG0667	Aldo Keto reductase
CBLAS_RS06800	COG0730	response to heat
CBLAS_RS06805	COG0736	holo-[acyl-carrier-protein] synthase activity
CBLAS_RS06815	COG1918	ferrous iron import across plasma membrane
CBLAS_RS06850	COG0735	belongs to the Fur family
CBLAS_RS06895	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CBLAS_RS06900	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CBLAS_RS06905	COG1027	Aspartate ammonia-lyase
CBLAS_RS06910	COG2207	Transcriptional regulator
CBLAS_RS06915	COG0804	urea catabolic process
CBLAS_RS06925	COG0831	urea catabolic process
CBLAS_RS06930	COG0829	nickel cation binding
CBLAS_RS06960	COG2081	HI0933 family
CBLAS_RS06975	COG0745	RESPONSE REGULATOR receiver
CBLAS_RS06990	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CBLAS_RS06995	COG0732	type I restriction modification DNA specificity domain
CBLAS_RS07105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBLAS_RS07120	COG0582	viral genome integration into host DNA
CBLAS_RS07145	COG0629	single-stranded DNA binding
CBLAS_RS07195	COG3451	type IV secretory pathway VirB4
CBLAS_RS07220	COG4962	Type ii secretion system protein e
CBLAS_RS07230	COG3505	Type IV secretory pathway VirD4
CBLAS_RS07260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CBLAS_RS07400	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CBLAS_RS07410	COG3045	CreA protein
CBLAS_RS07425	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CBLAS_RS07440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CBLAS_RS07450	COG1040	competence protein
CBLAS_RS07470	COG0481	GTPase activity
CBLAS_RS07485	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CBLAS_RS07500	COG1083	cytidylyl-transferase
CBLAS_RS07510	COG2089	acid synthase
CBLAS_RS07515	COG1216	Glycosyl transferase, family 2
CBLAS_RS07515	COG1442	glycosyl transferase family 8
CBLAS_RS07520	COG1216	Glycosyl transferase, family 2
CBLAS_RS07520	COG1442	glycosyl transferase family 8
CBLAS_RS07525	COG0482	sulfurtransferase activity
CBLAS_RS07535	COG0455	bacterial-type flagellum organization
CBLAS_RS07540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CBLAS_RS07545	COG0006	proline dipeptidase activity
CBLAS_RS07550	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CBLAS_RS07555	COG0616	signal peptide processing
CBLAS_RS07560	COG0471	metal ion transport
CBLAS_RS07565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CBLAS_RS07565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CBLAS_RS07575	COG0779	Required for maturation of 30S ribosomal subunits
CBLAS_RS07595	COG0083	homoserine kinase activity
CBLAS_RS07605	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CBLAS_RS07620	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBLAS_RS07625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CBLAS_RS07640	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CBLAS_RS07645	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CBLAS_RS07660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CBLAS_RS07665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CBLAS_RS07670	COG1047	Peptidyl-prolyl cis-trans
CBLAS_RS07695	COG0848	biopolymer transport protein
CBLAS_RS07700	COG0811	peptide transport
CBLAS_RS07710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CBLAS_RS07720	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CBLAS_RS07725	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CBLAS_RS07740	COG1475	DNA binding
CBLAS_RS07745	COG1192	Involved in chromosome partitioning
CBLAS_RS07750	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CBLAS_RS07750	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CBLAS_RS07755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CBLAS_RS07765	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CBLAS_RS07770	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CBLAS_RS07775	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CBLAS_RS07780	COG0277	FAD linked oxidase domain protein
CBLAS_RS07790	COG1620	l-lactate permease
CBLAS_RS07840	COG3210	domain, Protein
CBLAS_RS07840	COG3210	domain, Protein
CBLAS_RS07850	COG2831	hemolysin activation secretion protein
CBLAS_RS07865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CBLAS_RS07870	COG0730	response to heat
CBLAS_RS07910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CBLAS_RS07915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CBLAS_RS07920	COG1074	ATP-dependent DNA helicase activity
CBLAS_RS07935	COG0745	RESPONSE REGULATOR receiver
CBLAS_RS07945	COG0505	Belongs to the CarA family
CBLAS_RS07960	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CBLAS_RS07985	COG0252	asparaginase activity
CBLAS_RS08010	COG0772	Belongs to the SEDS family
CBLAS_RS08070	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CBLAS_RS08080	COG0437	4 iron, 4 sulfur cluster binding
CBLAS_RS08110	COG0314	molybdopterin synthase activity
CBLAS_RS08115	COG0303	'Molybdopterin
CBLAS_RS08140	COG1609	Transcriptional regulator
CBLAS_RS08140	COG2207	Transcriptional regulator
CBLAS_RS08145	COG2081	HI0933 family
CBLAS_RS08160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CBLAS_RS08165	COG0204	Acyl-transferase
CBLAS_RS08170	COG2814	Major facilitator Superfamily
CBLAS_RS08175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CBLAS_RS08195	COG0786	glutamate:sodium symporter activity
CBLAS_RS08205	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CBLAS_RS08215	COG0628	permease
CBLAS_RS08225	COG0708	Exodeoxyribonuclease III
CBLAS_RS08230	COG1252	NADH dehydrogenase
CBLAS_RS08235	COG0733	neurotransmitter:sodium symporter activity
CBLAS_RS08240	COG1115	amino acid carrier protein
CBLAS_RS08250	COG0437	4 iron, 4 sulfur cluster binding
CBLAS_RS08290	COG1921	L-seryl-tRNASec selenium transferase activity
CBLAS_RS08315	COG1929	Belongs to the glycerate kinase type-1 family
CBLAS_RS08320	COG2610	gluconate transmembrane transporter activity
CBLAS_RS08335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CBLAS_RS08345	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CBLAS_RS08350	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CBLAS_RS08355	COG0280	phosphate acetyltransferase
CBLAS_RS08355	COG0281	malic enzyme
CBLAS_RS08360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBLAS_RS08365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBLAS_RS08370	COG1741	Belongs to the pirin family
CBLAS_RS08380	COG2388	GCN5-related N-acetyl-transferase
CBLAS_RS08385	COG0439	Biotin carboxylase
CBLAS_RS08395	COG0076	glutamate decarboxylase activity
CBLAS_RS08405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBLAS_RS08410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CBLAS_RS08415	COG1629	transport
CBLAS_RS08415	COG4771	TonB-dependent receptor
CBLAS_RS08420	COG1120	ATPase activity
CBLAS_RS08425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBLAS_RS08435	COG4615	Cyclic peptide transporter
CBLAS_RS08445	COG0848	biopolymer transport protein
CBLAS_RS08455	COG4206	TonB-dependent receptor
CBLAS_RS08455	COG1629	transport
CBLAS_RS08465	COG1629	transport
CBLAS_RS08465	COG4206	TonB-dependent receptor
CBLAS_RS08470	COG0717	Belongs to the dCTP deaminase family
CBLAS_RS08475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CBLAS_RS08480	COG0569	domain protein
CBLAS_RS08480	COG0475	glutathione-regulated potassium exporter activity
CBLAS_RS08485	COG0372	Belongs to the citrate synthase family
CBLAS_RS08510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CBLAS_RS08515	COG0148	phosphopyruvate hydratase activity
CBLAS_RS08525	COG0351	phosphomethylpyrimidine kinase
CBLAS_RS08550	COG0582	viral genome integration into host DNA
CBLAS_RS08585	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CBLAS_RS08595	COG2233	PERMEase
CBLAS_RS08600	COG1715	Restriction endonuclease
CBLAS_RS08605	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CBLAS_RS08610	COG0575	Belongs to the CDS family
CBLAS_RS08615	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CBLAS_RS08620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CBLAS_RS08625	COG0746	molybdenum cofactor guanylyltransferase activity
CBLAS_RS08635	COG1253	flavin adenine dinucleotide binding
CBLAS_RS08645	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CBLAS_RS08660	COG0315	cyclic pyranopterin monophosphate synthase activity
CBLAS_RS08665	COG3422	double-strand break repair
CBLAS_RS08675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CBLAS_RS08685	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CBLAS_RS08690	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CBLAS_RS08695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBLAS_RS08705	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CBLAS_RS08710	COG0203	ribosomal protein L17
CBLAS_RS08715	COG0202	RNA polymerase activity
CBLAS_RS08720	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CBLAS_RS08730	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CBLAS_RS08735	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CBLAS_RS08740	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CBLAS_RS08750	COG0024	Methionine aminopeptidase
CBLAS_RS08755	COG0201	protein transport
CBLAS_RS08760	COG0200	Binds to the 23S rRNA
CBLAS_RS08765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CBLAS_RS08770	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CBLAS_RS08780	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CBLAS_RS08785	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CBLAS_RS08795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CBLAS_RS08800	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CBLAS_RS08810	COG0255	Belongs to the universal ribosomal protein uL29 family
CBLAS_RS08815	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CBLAS_RS08820	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CBLAS_RS08825	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CBLAS_RS08830	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CBLAS_RS08835	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CBLAS_RS08840	COG0089	rRNA binding
CBLAS_RS08845	COG0088	Forms part of the polypeptide exit tunnel
CBLAS_RS08850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CBLAS_RS08855	COG0051	transcription antitermination factor activity, RNA binding
CBLAS_RS08865	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CBLAS_RS08900	COG0243	molybdopterin cofactor binding
CBLAS_RS08945	COG2258	MOSC domain
CBLAS_RS08960	COG0778	Nitroreductase
CBLAS_RS08965	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CBLAS_RS08975	COG3104	oligopeptide transport
CBLAS_RS08985	COG1132	(ABC) transporter
CBLAS_RS09020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CBLAS_RS09035	COG0573	inorganic phosphate transmembrane transporter activity
CBLAS_RS09040	COG0581	inorganic phosphate transmembrane transporter activity
CBLAS_RS09045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CBLAS_RS09055	COG0745	RESPONSE REGULATOR receiver
CBLAS_RS09060	COG2205	protein histidine kinase activity
CBLAS_RS09060	COG3292	Two component regulator propeller
CBLAS_RS09060	COG0745	RESPONSE REGULATOR receiver
CBLAS_RS09075	COG1979	alcohol dehydrogenase
CBLAS_RS09080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBLAS_RS09085	COG1473	amidohydrolase
CBLAS_RS09090	COG3340	Belongs to the peptidase S51 family
CBLAS_RS09095	COG3069	C4-dicarboxylate transmembrane transporter activity
CBLAS_RS09100	COG2195	Cleaves the N-terminal amino acid of tripeptides
CBLAS_RS09105	COG2204	response regulator
CBLAS_RS09115	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CBLAS_RS09120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CBLAS_RS09130	COG0471	metal ion transport
CBLAS_RS09135	COG2249	NAD(P)H dehydrogenase (quinone) activity
CBLAS_RS09160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CBLAS_RS09175	COG1742	UPF0060 membrane protein
CBLAS_RS09190	COG0358	DNA primase activity
CBLAS_RS09200	COG0328	RNA-DNA hybrid ribonuclease activity
CBLAS_RS09205	COG0571	ribonuclease III activity
CBLAS_RS09210	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CBLAS_RS09220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBLAS_RS09225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CBLAS_RS09230	COG0668	transmembrane transport
CBLAS_RS09235	COG0288	reversible hydration of carbon dioxide
CBLAS_RS09240	COG0670	Belongs to the BI1 family
CBLAS_RS09245	COG0352	thiamine-phosphate diphosphorylase activity
CBLAS_RS09250	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CBLAS_RS09255	COG0233	cytoplasmic translational termination
CBLAS_RS09280	COG1116	anion transmembrane transporter activity
CBLAS_RS09290	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CBLAS_RS09295	COG2321	neutral zinc metallopeptidase
CBLAS_RS09335	COG3220	belongs to the UPF0276 family
CBLAS_RS09345	COG2259	Doxx family
CBLAS_RS09350	COG0745	RESPONSE REGULATOR receiver
CBLAS_RS09355	COG0642	Histidine kinase
CBLAS_RS09360	COG0129	dihydroxy-acid dehydratase activity
CBLAS_RS09365	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CBLAS_RS09370	COG2056	Na+-H+ antiporter family
CBLAS_RS09385	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group