locus-tag	class	description
CXQ83_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CXQ83_RS00010	COG0592	DNA-directed DNA polymerase activity
CXQ83_RS00015	COG0187	DNA topoisomerase II activity
CXQ83_RS00040	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXQ83_RS00045	COG3162	membrane
CXQ83_RS00050	COG2056	Na+-H+ antiporter family
CXQ83_RS00055	COG0070	glutamate synthase
CXQ83_RS00055	COG0069	glutamate synthase activity
CXQ83_RS00055	COG0067	glutamate synthase
CXQ83_RS00060	COG0493	'glutamate synthase
CXQ83_RS00070	COG1592	Rubrerythrin
CXQ83_RS00085	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CXQ83_RS00100	COG0179	Fumarylacetoacetate (FAA) hydrolase
CXQ83_RS00105	COG0564	pseudouridine synthase activity
CXQ83_RS00110	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CXQ83_RS00115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXQ83_RS00120	COG1823	symporter activity
CXQ83_RS00135	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CXQ83_RS00145	COG0252	asparaginase activity
CXQ83_RS00210	COG2814	Major facilitator Superfamily
CXQ83_RS00225	COG1217	gtp-binding protein TYPA
CXQ83_RS00240	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CXQ83_RS00265	COG0471	metal ion transport
CXQ83_RS00275	COG1611	Belongs to the LOG family
CXQ83_RS00335	COG1776	CheC inhibitor of MCP methylation
CXQ83_RS00335	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXQ83_RS00340	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXQ83_RS00345	COG1191	sigma factor activity
CXQ83_RS00355	COG0455	bacterial-type flagellum organization
CXQ83_RS00360	COG1419	protein localization to endoplasmic reticulum
CXQ83_RS00365	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CXQ83_RS00370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CXQ83_RS00375	COG0402	S-adenosylhomocysteine deaminase activity
CXQ83_RS00380	COG0616	signal peptide processing
CXQ83_RS00395	COG2703	oxygen carrier activity
CXQ83_RS00400	COG2703	oxygen carrier activity
CXQ83_RS00410	COG1139	Iron-sulfur cluster binding protein
CXQ83_RS00415	COG0247	lactate metabolic process
CXQ83_RS00420	COG1620	l-lactate permease
CXQ83_RS00430	COG1271	oxidase subunit
CXQ83_RS00435	COG1294	oxidase, subunit
CXQ83_RS00450	COG1794	racemase activity, acting on amino acids and derivatives
CXQ83_RS00455	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CXQ83_RS00460	COG1027	Aspartate ammonia-lyase
CXQ83_RS00465	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CXQ83_RS00485	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CXQ83_RS00490	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CXQ83_RS00510	COG1136	(ABC) transporter
CXQ83_RS00510	COG0577	efflux transmembrane transporter activity
CXQ83_RS00515	COG1136	(ABC) transporter
CXQ83_RS00515	COG0577	efflux transmembrane transporter activity
CXQ83_RS00535	COG0672	)-iron permease
CXQ83_RS00550	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CXQ83_RS00560	COG0791	NLP P60 protein
CXQ83_RS00565	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CXQ83_RS00570	COG0024	Methionine aminopeptidase
CXQ83_RS00585	COG3218	ABC-type transport auxiliary lipoprotein component
CXQ83_RS00585	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CXQ83_RS00590	COG1127	ABC transporter
CXQ83_RS00600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CXQ83_RS00615	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CXQ83_RS00620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CXQ83_RS00635	COG0358	DNA primase activity
CXQ83_RS00645	COG0328	RNA-DNA hybrid ribonuclease activity
CXQ83_RS00710	COG0848	biopolymer transport protein
CXQ83_RS00715	COG0811	peptide transport
CXQ83_RS00730	COG0814	amino acid
CXQ83_RS00735	COG1760	l-serine dehydratase
CXQ83_RS00795	COG1194	a g-specific adenine glycosylase
CXQ83_RS00800	COG0477	Major facilitator Superfamily
CXQ83_RS00810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXQ83_RS00815	COG1120	ATPase activity
CXQ83_RS00820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXQ83_RS00825	COG4771	TonB-dependent receptor
CXQ83_RS00830	COG0748	coenzyme F420 binding
CXQ83_RS00835	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CXQ83_RS00840	COG0268	Binds directly to 16S ribosomal RNA
CXQ83_RS00845	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CXQ83_RS00850	COG2046	Belongs to the sulfate adenylyltransferase family
CXQ83_RS00865	COG0489	protein tyrosine kinase activity
CXQ83_RS00870	COG2171	N-acyltransferase activity
CXQ83_RS00880	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CXQ83_RS00880	COG0140	phosphoribosyl-ATP diphosphatase activity
CXQ83_RS00900	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CXQ83_RS00900	COG0131	Imidazoleglycerol-phosphate dehydratase
CXQ83_RS00910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CXQ83_RS00915	COG0203	ribosomal protein L17
CXQ83_RS00920	COG0202	RNA polymerase activity
CXQ83_RS00930	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CXQ83_RS00940	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CXQ83_RS00945	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CXQ83_RS00995	COG4615	Cyclic peptide transporter
CXQ83_RS01010	COG0277	FAD linked oxidase domain protein
CXQ83_RS01020	COG0601	transmembrane transport
CXQ83_RS01025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXQ83_RS01030	COG4172	Belongs to the ABC transporter superfamily
CXQ83_RS01040	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXQ83_RS01050	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXQ83_RS01085	COG0839	Belongs to the complex I subunit 6 family
CXQ83_RS01095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CXQ83_RS01100	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXQ83_RS01140	COG1942	4-Oxalocrotonate Tautomerase
CXQ83_RS01145	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CXQ83_RS01150	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CXQ83_RS01160	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CXQ83_RS01165	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CXQ83_RS01170	COG1077	Cell shape determining protein MreB Mrl
CXQ83_RS01190	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CXQ83_RS01195	COG0372	Belongs to the citrate synthase family
CXQ83_RS01200	COG2079	MmgE PrpD family protein
CXQ83_RS01225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CXQ83_RS01235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CXQ83_RS01245	COG0835	chemotaxis
CXQ83_RS01250	COG0643	Histidine kinase
CXQ83_RS01250	COG2198	Histidine kinase
CXQ83_RS01250	COG0784	Response regulator, receiver
CXQ83_RS01255	COG0835	chemotaxis
CXQ83_RS01255	COG0784	Response regulator, receiver
CXQ83_RS01275	COG0428	transporter
CXQ83_RS01330	COG0454	-acetyltransferase
CXQ83_RS01355	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CXQ83_RS01375	COG4106	trans-aconitate 2-methyltransferase activity
CXQ83_RS01390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXQ83_RS01395	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CXQ83_RS01400	COG2076	Multidrug Resistance protein
CXQ83_RS01415	COG0193	aminoacyl-tRNA hydrolase activity
CXQ83_RS01425	COG0019	diaminopimelate decarboxylase activity
CXQ83_RS01450	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXQ83_RS01460	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CXQ83_RS01475	COG2226	methyltransferase
CXQ83_RS01495	COG1570	exodeoxyribonuclease VII activity
CXQ83_RS01505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CXQ83_RS01510	COG0416	fatty acid biosynthetic process
CXQ83_RS01515	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CXQ83_RS01525	COG0105	UTP biosynthetic process
CXQ83_RS01535	COG0450	alkyl hydroperoxide reductase
CXQ83_RS01540	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CXQ83_RS01545	COG1360	Flagellar Motor Protein
CXQ83_RS01550	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CXQ83_RS01580	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CXQ83_RS01585	COG0730	response to heat
CXQ83_RS01595	COG0512	Glutamine amidotransferase of anthranilate synthase
CXQ83_RS01595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CXQ83_RS01620	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXQ83_RS01620	COG1776	CheC inhibitor of MCP methylation
CXQ83_RS01635	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXQ83_RS01640	COG0745	RESPONSE REGULATOR receiver
CXQ83_RS01665	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CXQ83_RS01670	COG1981	membrane
CXQ83_RS01675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXQ83_RS01685	COG1538	Outer membrane efflux protein
CXQ83_RS01695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXQ83_RS01710	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CXQ83_RS01720	COG0754	glutathionylspermidine amidase activity
CXQ83_RS01725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CXQ83_RS01745	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CXQ83_RS01755	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CXQ83_RS01770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CXQ83_RS01775	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CXQ83_RS01785	COG2076	Multidrug Resistance protein
CXQ83_RS01790	COG1160	GTP binding
CXQ83_RS01795	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CXQ83_RS01820	COG0469	pyruvate kinase activity
CXQ83_RS01825	COG0579	oxidoreductase
CXQ83_RS01830	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CXQ83_RS01885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CXQ83_RS01905	COG1053	succinate dehydrogenase
CXQ83_RS01910	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CXQ83_RS01915	COG1160	GTP binding
CXQ83_RS01920	COG1132	(ABC) transporter
CXQ83_RS01970	COG0488	(ABC) transporter
CXQ83_RS01985	COG1739	Uncharacterized protein family UPF0029
CXQ83_RS02000	COG0840	transmembrane signaling receptor activity
CXQ83_RS02035	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CXQ83_RS02040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CXQ83_RS02050	COG1028	Short-chain dehydrogenase reductase Sdr
CXQ83_RS02060	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CXQ83_RS02065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXQ83_RS02070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXQ83_RS02085	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CXQ83_RS02095	COG2301	Belongs to the HpcH HpaI aldolase family
CXQ83_RS02100	COG4771	TonB-dependent receptor
CXQ83_RS02120	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CXQ83_RS02125	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CXQ83_RS02130	COG2176	DNA-directed DNA polymerase activity
CXQ83_RS02135	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CXQ83_RS02155	COG2121	Domain of unknown function (DUF374)
CXQ83_RS02160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CXQ83_RS02170	COG0195	Participates in both transcription termination and antitermination
CXQ83_RS02180	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CXQ83_RS02185	COG0612	Peptidase, M16
CXQ83_RS02190	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CXQ83_RS02195	COG2346	COG2346, Truncated hemoglobins
CXQ83_RS02210	COG0765	amino acid transport
CXQ83_RS02215	COG1126	abc transporter atp-binding protein
CXQ83_RS02240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CXQ83_RS02245	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CXQ83_RS02260	COG0250	Participates in transcription elongation, termination and antitermination
CXQ83_RS02265	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CXQ83_RS02270	COG0081	regulation of translation
CXQ83_RS02275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CXQ83_RS02280	COG0222	ribosome binding
CXQ83_RS02285	COG0085	RNA polymerase activity
CXQ83_RS02300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CXQ83_RS02310	COG2721	sulfolactate sulfo-lyase activity
CXQ83_RS02315	COG2271	Major facilitator Superfamily
CXQ83_RS02320	COG1028	Short-chain dehydrogenase reductase Sdr
CXQ83_RS02325	COG0738	Major facilitator superfamily
CXQ83_RS02335	COG3254	rhamnose metabolic process
CXQ83_RS02340	COG1012	belongs to the aldehyde dehydrogenase family
CXQ83_RS02345	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CXQ83_RS02350	COG0049	tRNA binding
CXQ83_RS02390	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CXQ83_RS02395	COG0004	ammonium transporteR
CXQ83_RS02410	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CXQ83_RS02420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CXQ83_RS02435	COG0542	response to heat
CXQ83_RS02445	COG0793	Belongs to the peptidase S41A family
CXQ83_RS02450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CXQ83_RS02455	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CXQ83_RS02460	COG0047	phosphoribosylformylglycinamidine synthase activity
CXQ83_RS02470	COG0204	Acyl-transferase
CXQ83_RS02475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CXQ83_RS02480	COG0326	Molecular chaperone. Has ATPase activity
CXQ83_RS02500	COG0768	penicillin binding
CXQ83_RS02505	COG1677	Flagellar hook-basal body complex protein FliE
CXQ83_RS02510	COG1558	bacterial-type flagellum-dependent cell motility
CXQ83_RS02515	COG1815	bacterial-type flagellum-dependent cell motility
CXQ83_RS02535	COG0039	L-malate dehydrogenase activity
CXQ83_RS02545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXQ83_RS02555	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CXQ83_RS02555	COG0674	pyruvate-flavodoxin oxidoreductase activity
CXQ83_RS02560	COG1013	pyruvate-flavodoxin oxidoreductase activity
CXQ83_RS02580	COG0142	geranyltranstransferase activity
CXQ83_RS02585	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CXQ83_RS02590	COG0442	prolyl-tRNA aminoacylation
CXQ83_RS02600	COG0181	hydroxymethylbilane synthase activity
CXQ83_RS02605	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CXQ83_RS02615	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CXQ83_RS02635	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CXQ83_RS02640	COG1289	transmembrane transporter activity
CXQ83_RS02645	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CXQ83_RS02650	COG0492	ferredoxin-NADP+ reductase activity
CXQ83_RS02665	COG0305	Participates in initiation and elongation during chromosome replication
CXQ83_RS02685	COG0772	Belongs to the SEDS family
CXQ83_RS02690	COG0564	pseudouridine synthase activity
CXQ83_RS02700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CXQ83_RS02705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CXQ83_RS02720	COG0528	UMP kinase activity
CXQ83_RS02725	COG1758	RNA polymerase activity
CXQ83_RS02730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXQ83_RS02735	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CXQ83_RS02755	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CXQ83_RS02760	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CXQ83_RS02765	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CXQ83_RS02770	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CXQ83_RS02780	COG0642	Histidine kinase
CXQ83_RS02785	COG0745	RESPONSE REGULATOR receiver
CXQ83_RS02795	COG4773	Receptor
CXQ83_RS02800	COG0733	neurotransmitter:sodium symporter activity
CXQ83_RS02805	COG2258	MOSC domain
CXQ83_RS02820	COG1473	amidohydrolase
CXQ83_RS02825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXQ83_RS02830	COG1136	(ABC) transporter
CXQ83_RS02830	COG0577	efflux transmembrane transporter activity
CXQ83_RS02835	COG1538	Outer membrane efflux protein
CXQ83_RS02850	COG1696	Membrane protein involved in D-alanine export
CXQ83_RS02855	COG1528	Iron-storage protein
CXQ83_RS02860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CXQ83_RS02865	COG0573	inorganic phosphate transmembrane transporter activity
CXQ83_RS02870	COG0581	inorganic phosphate transmembrane transporter activity
CXQ83_RS02885	COG0534	Mate efflux family protein
CXQ83_RS02900	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CXQ83_RS02910	COG0298	carbon dioxide binding
CXQ83_RS02915	COG0409	Hydrogenase expression formation protein
CXQ83_RS02920	COG0309	Hydrogenase expression formation protein (HypE)
CXQ83_RS02925	COG0375	protein maturation
CXQ83_RS02930	COG1466	dna polymerase III delta subunit
CXQ83_RS02935	COG0557	exoribonuclease II activity
CXQ83_RS02940	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CXQ83_RS02950	COG0758	DNA mediated transformation
CXQ83_RS02965	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CXQ83_RS02970	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CXQ83_RS02975	COG0563	adenylate kinase activity
CXQ83_RS02990	COG0497	DNA recombination
CXQ83_RS03000	COG0084	hydrolase, TatD family'
CXQ83_RS03005	COG0741	lytic transglycosylase activity
CXQ83_RS03005	COG1388	LysM domain
CXQ83_RS03010	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CXQ83_RS03060	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CXQ83_RS03065	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CXQ83_RS03080	COG0137	argininosuccinate synthase activity
CXQ83_RS03085	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CXQ83_RS03090	COG0802	atpase or kinase
CXQ83_RS03095	COG1137	ATPase activity
CXQ83_RS03100	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CXQ83_RS03105	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CXQ83_RS03130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CXQ83_RS03135	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CXQ83_RS03145	COG0280	phosphate acetyltransferase
CXQ83_RS03150	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CXQ83_RS03165	COG0275	rRNA processing
CXQ83_RS03170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXQ83_RS03175	COG0849	cell division
CXQ83_RS03180	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CXQ83_RS03185	COG4786	Flagellar basal body rod
CXQ83_RS03190	COG4786	Flagellar basal body rod
CXQ83_RS03195	COG0174	glutamine synthetase
CXQ83_RS03205	COG0826	peptidase U32
CXQ83_RS03210	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CXQ83_RS03225	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CXQ83_RS03235	COG1519	Transferase
CXQ83_RS03240	COG0564	pseudouridine synthase activity
CXQ83_RS03245	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CXQ83_RS03250	COG0228	four-way junction DNA binding
CXQ83_RS03255	COG1837	Belongs to the UPF0109 family
CXQ83_RS03260	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CXQ83_RS03265	COG0336	Belongs to the RNA methyltransferase TrmD family
CXQ83_RS03270	COG0335	large ribosomal subunit rRNA binding
CXQ83_RS03275	COG2351	hydroxyisourate hydrolase activity
CXQ83_RS03280	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CXQ83_RS03285	COG1393	Belongs to the ArsC family
CXQ83_RS03290	COG0587	DNA-directed DNA polymerase activity
CXQ83_RS03295	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CXQ83_RS03310	COG2890	protein-(glutamine-N5) methyltransferase activity
CXQ83_RS03315	COG0501	Belongs to the peptidase M48B family
CXQ83_RS03325	COG0521	Mo-molybdopterin cofactor biosynthetic process
CXQ83_RS03330	COG0598	Magnesium transport protein CorA
CXQ83_RS03380	COG0675	Transposase, IS605 OrfB family
CXQ83_RS03390	COG4771	TonB-dependent receptor
CXQ83_RS03395	COG1420	regulation of RNA biosynthetic process
CXQ83_RS03400	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CXQ83_RS03405	COG0443	Heat shock 70 kDa protein
CXQ83_RS03425	COG0436	Aminotransferase
CXQ83_RS03430	COG1045	serine acetyltransferase
CXQ83_RS03435	COG1166	arginine decarboxylase activity
CXQ83_RS03445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CXQ83_RS03450	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CXQ83_RS03455	COG0163	prenyltransferase activity
CXQ83_RS03465	COG1464	Belongs to the NlpA lipoprotein family
CXQ83_RS03470	COG1464	Belongs to the NlpA lipoprotein family
CXQ83_RS03475	COG1464	Belongs to the NlpA lipoprotein family
CXQ83_RS03480	COG2011	ABC-type metal ion transport system permease component
CXQ83_RS03485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CXQ83_RS03500	COG0210	DNA helicase
CXQ83_RS03510	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CXQ83_RS03520	COG0437	4 iron, 4 sulfur cluster binding
CXQ83_RS03525	COG0348	domain, Protein
CXQ83_RS03530	COG3043	anaerobic respiration
CXQ83_RS03545	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CXQ83_RS03570	COG0617	tRNA 3'-terminal CCA addition
CXQ83_RS03575	COG0788	formyltetrahydrofolate deformylase activity
CXQ83_RS03585	COG0318	PFAM AMP-dependent synthetase and ligase
CXQ83_RS03585	COG0204	Acyl-transferase
CXQ83_RS03605	COG1181	Belongs to the D-alanine--D-alanine ligase family
CXQ83_RS03610	COG0632	four-way junction helicase activity
CXQ83_RS03620	COG0728	peptidoglycan biosynthetic process
CXQ83_RS03625	COG0215	cysteine-tRNA ligase activity
CXQ83_RS03630	COG1132	(ABC) transporter
CXQ83_RS03635	COG0167	dihydroorotate dehydrogenase activity
CXQ83_RS03640	COG0612	Peptidase, M16
CXQ83_RS03650	COG1028	Short-chain dehydrogenase reductase Sdr
CXQ83_RS03665	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CXQ83_RS03670	COG1663	tetraacyldisaccharide 4'-kinase activity
CXQ83_RS03675	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CXQ83_RS03680	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CXQ83_RS03725	COG1338	Plays a role in the flagellum-specific transport system
CXQ83_RS03760	COG0101	tRNA pseudouridine synthase activity
CXQ83_RS03765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CXQ83_RS03785	COG1757	Na H antiporter
CXQ83_RS03790	COG4221	oxidoreductase activity
CXQ83_RS03800	COG1049	propionate catabolic process, 2-methylcitrate cycle
CXQ83_RS03805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXQ83_RS03815	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXQ83_RS03815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXQ83_RS03825	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CXQ83_RS03850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CXQ83_RS03855	COG1408	metallophosphoesterase
CXQ83_RS03860	COG0688	phosphatidylethanolamine metabolic process
CXQ83_RS03885	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CXQ83_RS03900	COG0681	Belongs to the peptidase S26 family
CXQ83_RS03910	COG0803	Belongs to the bacterial solute-binding protein 9 family
CXQ83_RS03965	COG0824	Thioesterase
CXQ83_RS03980	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CXQ83_RS03990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CXQ83_RS03995	COG0706	membrane insertase activity
CXQ83_RS04010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CXQ83_RS04015	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CXQ83_RS04020	COG0138	bifunctional purine biosynthesis protein purh
CXQ83_RS04025	COG0840	transmembrane signaling receptor activity
CXQ83_RS04035	COG2957	Belongs to the agmatine deiminase family
CXQ83_RS04040	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CXQ83_RS04055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CXQ83_RS04065	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CXQ83_RS04090	COG0765	amino acid transport
CXQ83_RS04130	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CXQ83_RS04140	COG0642	Histidine kinase
CXQ83_RS04155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CXQ83_RS04160	COG1196	nuclear chromosome segregation
CXQ83_RS04160	COG1674	ftsk spoiiie
CXQ83_RS04165	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CXQ83_RS04170	COG1959	2 iron, 2 sulfur cluster binding
CXQ83_RS04175	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CXQ83_RS04180	COG2404	hydrolase activity, acting on ester bonds
CXQ83_RS04205	COG0582	viral genome integration into host DNA
CXQ83_RS04215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CXQ83_RS04215	COG0512	Glutamine amidotransferase of anthranilate synthase
CXQ83_RS04230	COG0303	'Molybdopterin
CXQ83_RS04240	COG0488	(ABC) transporter
CXQ83_RS04245	COG2202	Pas domain
CXQ83_RS04245	COG2205	protein histidine kinase activity
CXQ83_RS04250	COG0745	RESPONSE REGULATOR receiver
CXQ83_RS04255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CXQ83_RS04265	COG0539	negative regulation of cytoplasmic translation
CXQ83_RS04265	COG1185	polyribonucleotide nucleotidyltransferase activity
CXQ83_RS04280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXQ83_RS04280	COG0072	phenylalanine-tRNA ligase activity
CXQ83_RS04285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CXQ83_RS04290	COG0537	adenosine 5'-monophosphoramidase activity
CXQ83_RS04300	COG0765	amino acid transport
CXQ83_RS04305	COG1126	abc transporter atp-binding protein
CXQ83_RS04310	COG1115	amino acid carrier protein
CXQ83_RS04315	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CXQ83_RS04320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXQ83_RS04345	COG1999	signal sequence binding
CXQ83_RS04350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXQ83_RS04355	COG0776	regulation of translation
CXQ83_RS04370	COG2879	small protein
CXQ83_RS04375	COG1966	Carbon starvation protein
CXQ83_RS04380	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CXQ83_RS04385	COG0765	amino acid transport
CXQ83_RS04390	COG0765	amino acid transport
CXQ83_RS04395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXQ83_RS04400	COG1126	abc transporter atp-binding protein
CXQ83_RS04405	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CXQ83_RS04410	COG2201	protein-glutamate methylesterase activity
CXQ83_RS04425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CXQ83_RS04435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CXQ83_RS04440	COG0012	GTP binding
CXQ83_RS04460	COG0733	neurotransmitter:sodium symporter activity
CXQ83_RS04465	COG0733	neurotransmitter:sodium symporter activity
CXQ83_RS04545	COG0863	Belongs to the N(4) N(6)-methyltransferase family
CXQ83_RS04820	COG1525	nuclease
CXQ83_RS04825	COG2195	Cleaves the N-terminal amino acid of tripeptides
CXQ83_RS04830	COG0477	Major facilitator Superfamily
CXQ83_RS04835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXQ83_RS04845	COG3022	response to hydroperoxide
CXQ83_RS04860	COG0247	lactate metabolic process
CXQ83_RS04860	COG2181	nitrate reductase activity
CXQ83_RS04865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXQ83_RS04875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CXQ83_RS04880	COG0113	porphobilinogen synthase activity
CXQ83_RS04885	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CXQ83_RS04890	COG0357	Ribosomal RNA small subunit methyltransferase G
CXQ83_RS04900	COG2855	membrane
CXQ83_RS04905	COG0583	DNA-binding transcription factor activity
CXQ83_RS04910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXQ83_RS04930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CXQ83_RS04935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CXQ83_RS04955	COG0343	queuine tRNA-ribosyltransferase activity
CXQ83_RS04985	COG1333	cytochrome c biogenesis protein
CXQ83_RS04985	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXQ83_RS05025	COG4773	Receptor
CXQ83_RS05035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CXQ83_RS05040	COG2204	response regulator
CXQ83_RS05055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CXQ83_RS05070	COG0481	GTPase activity
CXQ83_RS05105	COG0439	Biotin carboxylase
CXQ83_RS05110	COG0772	Belongs to the SEDS family
CXQ83_RS05135	COG0352	thiamine-phosphate diphosphorylase activity
CXQ83_RS05185	COG1193	negative regulation of DNA recombination
CXQ83_RS05230	COG0516	GMP reductase activity
CXQ83_RS05230	COG0517	IMP dehydrogenase activity
CXQ83_RS05235	COG0154	amidase activity
CXQ83_RS05240	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CXQ83_RS05245	COG1058	Belongs to the CinA family
CXQ83_RS05245	COG1546	Belongs to the CinA family
CXQ83_RS05255	COG0778	Nitroreductase
CXQ83_RS05260	COG0778	Nitroreductase
CXQ83_RS05265	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CXQ83_RS05270	COG0750	zinc metalloprotease
CXQ83_RS05285	COG2271	Major facilitator Superfamily
CXQ83_RS05290	COG0360	Binds together with S18 to 16S ribosomal RNA
CXQ83_RS05295	COG0629	single-stranded DNA binding
CXQ83_RS05300	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CXQ83_RS05305	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CXQ83_RS05315	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CXQ83_RS05320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CXQ83_RS05345	COG0352	thiamine-phosphate diphosphorylase activity
CXQ83_RS05365	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CXQ83_RS05375	COG0739	heme binding
CXQ83_RS05400	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXQ83_RS05405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXQ83_RS05410	COG1862	Preprotein translocase
CXQ83_RS05415	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CXQ83_RS05430	COG1028	Short-chain dehydrogenase reductase Sdr
CXQ83_RS05440	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CXQ83_RS05445	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CXQ83_RS05485	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CXQ83_RS05490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXQ83_RS05505	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CXQ83_RS05510	COG2095	MarC family integral membrane protein
CXQ83_RS05515	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CXQ83_RS05520	COG2833	Protein of unknown function (DUF455)
CXQ83_RS05525	COG1183	phosphatidylcholine synthase activity
CXQ83_RS05535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CXQ83_RS05545	COG0745	RESPONSE REGULATOR receiver
CXQ83_RS05550	COG1086	Polysaccharide biosynthesis protein
CXQ83_RS05555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CXQ83_RS05560	COG0110	maltose O-acetyltransferase activity
CXQ83_RS05565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CXQ83_RS05570	COG0438	transferase activity, transferring glycosyl groups
CXQ83_RS05580	COG0438	transferase activity, transferring glycosyl groups
CXQ83_RS05585	COG1215	transferase activity, transferring glycosyl groups
CXQ83_RS05590	COG0438	transferase activity, transferring glycosyl groups
CXQ83_RS05595	COG1132	(ABC) transporter
CXQ83_RS05600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CXQ83_RS05650	COG1216	Glycosyl transferase, family 2
CXQ83_RS05675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXQ83_RS05680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CXQ83_RS05695	COG2217	Heavy metal translocating P-type atpase
CXQ83_RS05700	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CXQ83_RS05705	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CXQ83_RS05710	COG2217	Heavy metal translocating P-type atpase
CXQ83_RS05730	COG3610	response to peptide
CXQ83_RS05740	COG0039	L-malate dehydrogenase activity
CXQ83_RS05745	COG0586	Pfam SNARE associated Golgi protein
CXQ83_RS05750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CXQ83_RS05755	COG0217	transcriptional regulatory protein
CXQ83_RS05770	COG0018	arginyl-trna synthetase
CXQ83_RS05775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXQ83_RS05780	COG0194	GDP metabolic process
CXQ83_RS05795	COG1136	(ABC) transporter
CXQ83_RS05805	COG0052	Belongs to the universal ribosomal protein uS2 family
CXQ83_RS05810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CXQ83_RS05820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CXQ83_RS05825	COG0723	plastoquinol--plastocyanin reductase activity
CXQ83_RS05830	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CXQ83_RS05855	COG1301	dicarboxylic acid transport
CXQ83_RS05870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CXQ83_RS05910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CXQ83_RS05925	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CXQ83_RS05945	COG0523	cobalamin synthesis protein
CXQ83_RS05950	COG0552	protein localization to endoplasmic reticulum
CXQ83_RS05980	COG1295	ribonuclease BN
CXQ83_RS05995	COG0739	heme binding
CXQ83_RS06005	COG1496	oxidoreductase activity
CXQ83_RS06020	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CXQ83_RS06035	COG0642	Histidine kinase
CXQ83_RS06040	COG0745	RESPONSE REGULATOR receiver
CXQ83_RS06045	COG2703	oxygen carrier activity
CXQ83_RS06090	COG0642	Histidine kinase
CXQ83_RS06095	COG0745	RESPONSE REGULATOR receiver
CXQ83_RS06100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXQ83_RS06105	COG0484	heat shock protein binding
CXQ83_RS06110	COG0789	Transcriptional regulator
CXQ83_RS06130	COG0751	glycine-tRNA ligase activity
CXQ83_RS06135	COG0739	heme binding
CXQ83_RS06160	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CXQ83_RS06180	COG0731	radical SAM domain protein
CXQ83_RS06210	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CXQ83_RS06235	COG1185	polyribonucleotide nucleotidyltransferase activity
CXQ83_RS06250	COG1942	4-Oxalocrotonate Tautomerase
CXQ83_RS06265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXQ83_RS06285	COG0191	fructose-bisphosphate aldolase activity
CXQ83_RS06290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXQ83_RS06295	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CXQ83_RS06305	COG2860	membrane
CXQ83_RS06315	COG2890	protein-(glutamine-N5) methyltransferase activity
CXQ83_RS06335	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CXQ83_RS06340	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CXQ83_RS06355	COG0527	aspartate kinase activity
CXQ83_RS06360	COG0494	nUDIX hydrolase
CXQ83_RS06365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXQ83_RS06375	COG0805	protein transport
CXQ83_RS06390	COG0440	acetolactate synthase activity
CXQ83_RS06395	COG0028	Belongs to the TPP enzyme family
CXQ83_RS06405	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CXQ83_RS06405	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CXQ83_RS06425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CXQ83_RS06430	COG0569	domain protein
CXQ83_RS06445	COG0281	malic enzyme
CXQ83_RS06445	COG0280	phosphate acetyltransferase
CXQ83_RS06450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CXQ83_RS06455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXQ83_RS06460	COG0439	Biotin carboxylase
CXQ83_RS06465	COG0511	ligase activity, forming carbon-carbon bonds
CXQ83_RS06475	COG1086	Polysaccharide biosynthesis protein
CXQ83_RS06480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CXQ83_RS06485	COG4310	Domain of unknown function (DUF2172)
CXQ83_RS06515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CXQ83_RS06570	COG1083	cytidylyl-transferase
CXQ83_RS06575	COG3980	spore coat polysaccharide biosynthesis protein
CXQ83_RS06580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXQ83_RS06585	COG0107	imidazoleglycerol-phosphate synthase activity
CXQ83_RS06590	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CXQ83_RS06610	COG2089	acid synthase
CXQ83_RS06620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXQ83_RS06625	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CXQ83_RS06635	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CXQ83_RS06655	COG2089	acid synthase
CXQ83_RS06660	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CXQ83_RS06665	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CXQ83_RS06675	COG1083	cytidylyl-transferase
CXQ83_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
CXQ83_RS06730	COG2165	general secretion pathway protein
CXQ83_RS06750	COG0575	Belongs to the CDS family
CXQ83_RS06775	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXQ83_RS06780	COG4605	iron ion homeostasis
CXQ83_RS06785	COG4604	ABC transporter, ATP-binding protein
CXQ83_RS06790	COG4607	ABC-type enterochelin transport system periplasmic component
CXQ83_RS06805	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CXQ83_RS06815	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CXQ83_RS06840	COG0628	permease
CXQ83_RS06845	COG0114	fumarate hydratase activity
CXQ83_RS06850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CXQ83_RS06860	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CXQ83_RS06865	COG2252	PERMEase
CXQ83_RS06875	COG2853	Lipoprotein
CXQ83_RS06900	COG2814	Major facilitator Superfamily
CXQ83_RS06915	COG3276	selenocysteine insertion sequence binding
CXQ83_RS06935	COG0716	FMN binding
CXQ83_RS06950	COG0753	catalase activity
CXQ83_RS06960	COG2964	Protein conserved in bacteria
CXQ83_RS06965	COG0251	oxidation-reduction process
CXQ83_RS06970	COG3069	C4-dicarboxylate transmembrane transporter activity
CXQ83_RS06980	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CXQ83_RS06990	COG1918	ferrous iron import across plasma membrane
CXQ83_RS06995	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CXQ83_RS07000	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CXQ83_RS07005	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CXQ83_RS07015	COG0126	phosphoglycerate kinase activity
CXQ83_RS07025	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CXQ83_RS07045	COG1580	Controls the rotational direction of flagella during chemotaxis
CXQ83_RS07050	COG0736	holo-[acyl-carrier-protein] synthase activity
CXQ83_RS07060	COG2124	cytochrome p450
CXQ83_RS07110	COG1028	Short-chain dehydrogenase reductase Sdr
CXQ83_RS07160	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CXQ83_RS07165	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CXQ83_RS07165	COG0517	IMP dehydrogenase activity
CXQ83_RS07215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CXQ83_RS07230	COG0585	pseudouridine synthase activity
CXQ83_RS07235	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CXQ83_RS07255	COG1706	bacterial-type flagellum-dependent cell motility
CXQ83_RS07260	COG3951	Flagellar rod assembly protein muramidase FlgJ
CXQ83_RS07285	COG0730	response to heat
CXQ83_RS07290	COG1459	type II secretion system
CXQ83_RS07325	COG0546	phosphoglycolate phosphatase activity
CXQ83_RS07335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CXQ83_RS07340	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CXQ83_RS07355	COG1074	ATP-dependent DNA helicase activity
CXQ83_RS07360	COG2887	Belongs to the helicase family. UvrD subfamily
CXQ83_RS07405	COG0745	RESPONSE REGULATOR receiver
CXQ83_RS07420	COG0505	Belongs to the CarA family
CXQ83_RS07455	COG0425	Belongs to the sulfur carrier protein TusA family
CXQ83_RS07460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXQ83_RS07475	COG0425	Belongs to the sulfur carrier protein TusA family
CXQ83_RS07485	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CXQ83_RS07495	COG0437	4 iron, 4 sulfur cluster binding
CXQ83_RS07530	COG0314	molybdopterin synthase activity
CXQ83_RS07535	COG0303	'Molybdopterin
CXQ83_RS07540	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CXQ83_RS07565	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CXQ83_RS07570	COG0237	dephospho-CoA kinase activity
CXQ83_RS07575	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CXQ83_RS07580	COG2992	FlgJ-related protein
CXQ83_RS07595	COG0783	Belongs to the Dps family
CXQ83_RS07615	COG3839	Belongs to the ABC transporter superfamily
CXQ83_RS07620	COG4662	Binding-protein-dependent transport system inner membrane component
CXQ83_RS07625	COG2998	abc-type tungstate transport system, permease component
CXQ83_RS07635	COG1914	H( )-stimulated, divalent metal cation uptake system
CXQ83_RS07640	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CXQ83_RS07645	COG1984	allophanate hydrolase subunit 2
CXQ83_RS07660	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXQ83_RS07675	COG1064	alcohol dehydrogenase
CXQ83_RS07705	COG3545	Serine hydrolase
CXQ83_RS07715	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXQ83_RS07755	COG2264	protein methyltransferase activity
CXQ83_RS07765	COG0418	dihydroorotase activity
CXQ83_RS07775	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CXQ83_RS07780	COG2194	sulfuric ester hydrolase activity
CXQ83_RS07785	COG0708	Exodeoxyribonuclease III
CXQ83_RS07795	COG2921	Belongs to the UPF0250 family
CXQ83_RS07825	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CXQ83_RS07830	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CXQ83_RS07850	COG0668	transmembrane transport
CXQ83_RS07855	COG0288	reversible hydration of carbon dioxide
CXQ83_RS07860	COG0670	Belongs to the BI1 family
CXQ83_RS07865	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXQ83_RS07885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXQ83_RS07895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXQ83_RS07900	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CXQ83_RS07905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CXQ83_RS07910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CXQ83_RS07930	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CXQ83_RS07940	COG1968	undecaprenyl-diphosphatase activity
CXQ83_RS07950	COG4953	penicillin-binding protein 1C
CXQ83_RS07955	COG2373	Large extracellular alpha-helical protein
CXQ83_RS07970	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CXQ83_RS07970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CXQ83_RS07980	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CXQ83_RS07995	COG0243	molybdopterin cofactor binding
CXQ83_RS08010	COG1157	protein secretion by the type III secretion system
CXQ83_RS08015	COG0302	gtp cyclohydrolase
CXQ83_RS08030	COG0242	peptide deformylase activity
CXQ83_RS08035	COG0606	chelatase, subunit chli
CXQ83_RS08045	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CXQ83_RS08045	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CXQ83_RS08050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CXQ83_RS08065	COG0861	Integral membrane protein TerC family
CXQ83_RS08070	COG2824	Alkylphosphonate utilization operon protein PhnA
CXQ83_RS08080	COG1253	flavin adenine dinucleotide binding
CXQ83_RS08090	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CXQ83_RS08100	COG0848	biopolymer transport protein
CXQ83_RS08105	COG0811	peptide transport
CXQ83_RS08110	COG4206	TonB-dependent receptor
CXQ83_RS08110	COG1629	transport
CXQ83_RS08120	COG1840	ABC-type Fe3 transport system, periplasmic component
CXQ83_RS08140	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CXQ83_RS08160	COG1971	Probably functions as a manganese efflux pump
CXQ83_RS08185	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CXQ83_RS08190	COG0602	queuosine metabolic process
CXQ83_RS08210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CXQ83_RS08215	COG0254	rRNA binding
CXQ83_RS08220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CXQ83_RS08240	COG0436	Aminotransferase
CXQ83_RS08245	COG0460	homoserine dehydrogenase
CXQ83_RS08255	COG3118	belongs to the thioredoxin family
CXQ83_RS08260	COG0492	ferredoxin-NADP+ reductase activity
CXQ83_RS08280	COG1121	(ABC) transporter
CXQ83_RS08285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXQ83_RS08295	COG1401	restriction endodeoxyribonuclease activity
CXQ83_RS08305	COG0779	Required for maturation of 30S ribosomal subunits
CXQ83_RS08325	COG0083	homoserine kinase activity
CXQ83_RS08350	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXQ83_RS08355	COG0483	inositol monophosphate 1-phosphatase activity
CXQ83_RS08360	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CXQ83_RS08370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXQ83_RS08380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXQ83_RS08425	COG0037	tRNA processing
CXQ83_RS08430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CXQ83_RS08435	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CXQ83_RS08440	COG1047	Peptidyl-prolyl cis-trans
CXQ83_RS08465	COG0848	biopolymer transport protein
CXQ83_RS08470	COG0811	peptide transport
CXQ83_RS08475	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CXQ83_RS08480	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CXQ83_RS08495	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CXQ83_RS08500	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CXQ83_RS08510	COG1475	DNA binding
CXQ83_RS08515	COG1192	Involved in chromosome partitioning
CXQ83_RS08520	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CXQ83_RS08520	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CXQ83_RS08570	COG1793	dna ligase
CXQ83_RS08585	COG0148	phosphopyruvate hydratase activity
CXQ83_RS08590	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CXQ83_RS08595	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CXQ83_RS08600	COG1987	bacterial-type flagellum assembly
CXQ83_RS08615	COG1218	3'(2'),5'-bisphosphate nucleotidase
CXQ83_RS08620	COG0372	Belongs to the citrate synthase family
CXQ83_RS08635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CXQ83_RS08645	COG0201	protein transport
CXQ83_RS08650	COG0200	Binds to the 23S rRNA
CXQ83_RS08655	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CXQ83_RS08660	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CXQ83_RS08665	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CXQ83_RS08670	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CXQ83_RS08675	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CXQ83_RS08680	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CXQ83_RS08685	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CXQ83_RS08690	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CXQ83_RS08695	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CXQ83_RS08700	COG0255	Belongs to the universal ribosomal protein uL29 family
CXQ83_RS08705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CXQ83_RS08710	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CXQ83_RS08715	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CXQ83_RS08720	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CXQ83_RS08735	COG0088	Forms part of the polypeptide exit tunnel
CXQ83_RS08740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CXQ83_RS08745	COG0051	transcription antitermination factor activity, RNA binding
CXQ83_RS08750	COG1187	pseudouridine synthase activity
CXQ83_RS08755	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CXQ83_RS08810	COG0066	3-isopropylmalate dehydratase activity
CXQ83_RS08820	COG0473	3-isopropylmalate dehydrogenase activity
CXQ83_RS08845	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CXQ83_RS08855	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CXQ83_RS08870	COG1749	Flagellar hook protein flgE
CXQ83_RS08935	COG3041	Addiction module toxin RelE StbE family
CXQ83_RS09035	COG1598	PFAM Uncharacterised protein family UPF0150
CXQ83_RS09220	COG3501	Rhs element vgr protein
CXQ83_RS09350	COG3501	Rhs element vgr protein
CXQ83_RS09410	COG0582	viral genome integration into host DNA