locus-tag	class	description
A0071_RS00005	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A0071_RS00010	COG1137	ATPase activity
A0071_RS00020	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A0071_RS00025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A0071_RS00040	COG2089	acid synthase
A0071_RS00060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A0071_RS00065	COG3980	spore coat polysaccharide biosynthesis protein
A0071_RS00070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A0071_RS00100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A0071_RS00105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A0071_RS00130	COG1942	4-Oxalocrotonate Tautomerase
A0071_RS00155	COG0840	transmembrane signaling receptor activity
A0071_RS00160	COG0803	Belongs to the bacterial solute-binding protein 9 family
A0071_RS00165	COG1121	(ABC) transporter
A0071_RS00170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A0071_RS00180	COG1401	restriction endodeoxyribonuclease activity
A0071_RS00185	COG0471	metal ion transport
A0071_RS00190	COG1253	flavin adenine dinucleotide binding
A0071_RS00195	COG1253	flavin adenine dinucleotide binding
A0071_RS00205	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A0071_RS00210	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
A0071_RS00215	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
A0071_RS00220	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
A0071_RS00240	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A0071_RS00245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A0071_RS00250	COG1758	RNA polymerase activity
A0071_RS00255	COG0528	UMP kinase activity
A0071_RS00270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A0071_RS00275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A0071_RS00285	COG0564	pseudouridine synthase activity
A0071_RS00290	COG0772	Belongs to the SEDS family
A0071_RS00300	COG1620	l-lactate permease
A0071_RS00305	COG0247	lactate metabolic process
A0071_RS00310	COG1139	Iron-sulfur cluster binding protein
A0071_RS00325	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A0071_RS00335	COG0328	RNA-DNA hybrid ribonuclease activity
A0071_RS00345	COG0358	DNA primase activity
A0071_RS00370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A0071_RS00390	COG0556	nucleotide-excision repair
A0071_RS00420	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A0071_RS00435	COG2853	Lipoprotein
A0071_RS00460	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
A0071_RS00470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A0071_RS00490	COG0505	Belongs to the CarA family
A0071_RS00530	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A0071_RS00530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A0071_RS00535	COG1295	ribonuclease BN
A0071_RS00565	COG0552	protein localization to endoplasmic reticulum
A0071_RS00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A0071_RS00630	COG0506	proline dehydrogenase activity
A0071_RS00630	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A0071_RS00630	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A0071_RS00655	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A0071_RS00665	COG0437	4 iron, 4 sulfur cluster binding
A0071_RS00695	COG0314	molybdopterin synthase activity
A0071_RS00700	COG0303	'Molybdopterin
A0071_RS00710	COG2814	Major facilitator Superfamily
A0071_RS00720	COG0656	L-ascorbic acid biosynthetic process
A0071_RS00725	COG1064	alcohol dehydrogenase
A0071_RS00730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0071_RS00750	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A0071_RS00755	COG0557	exoribonuclease II activity
A0071_RS00765	COG0375	protein maturation
A0071_RS00780	COG0409	Hydrogenase expression formation protein
A0071_RS00785	COG0298	carbon dioxide binding
A0071_RS00795	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A0071_RS00810	COG0534	Mate efflux family protein
A0071_RS00820	COG0440	acetolactate synthase activity
A0071_RS00825	COG0028	Belongs to the TPP enzyme family
A0071_RS00830	COG0305	Participates in initiation and elongation during chromosome replication
A0071_RS00835	COG0052	Belongs to the universal ribosomal protein uS2 family
A0071_RS00845	COG1136	(ABC) transporter
A0071_RS00850	COG1684	flagellar biosynthetic protein fliR
A0071_RS00865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A0071_RS00870	COG0018	arginyl-trna synthetase
A0071_RS00905	COG0488	(ABC) transporter
A0071_RS01070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A0071_RS01105	COG4962	Type ii secretion system protein e
A0071_RS01165	COG1598	PFAM Uncharacterised protein family UPF0150
A0071_RS01225	COG0582	viral genome integration into host DNA
A0071_RS01240	COG3069	C4-dicarboxylate transmembrane transporter activity
A0071_RS01290	COG1749	Flagellar hook protein flgE
A0071_RS01295	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A0071_RS01310	COG1217	gtp-binding protein TYPA
A0071_RS01320	COG0418	dihydroorotase activity
A0071_RS01330	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A0071_RS01335	COG2194	sulfuric ester hydrolase activity
A0071_RS01340	COG0708	Exodeoxyribonuclease III
A0071_RS01345	COG1971	Probably functions as a manganese efflux pump
A0071_RS01355	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A0071_RS01365	COG1222	aaa ATPase
A0071_RS01375	COG1666	GTP binding
A0071_RS01380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A0071_RS01385	COG0754	glutathionylspermidine amidase activity
A0071_RS01395	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A0071_RS01400	COG0348	domain, Protein
A0071_RS01425	COG1981	membrane
A0071_RS01455	COG0745	RESPONSE REGULATOR receiver
A0071_RS01475	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A0071_RS01475	COG1776	CheC inhibitor of MCP methylation
A0071_RS01490	COG0133	tryptophan synthase activity
A0071_RS01500	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A0071_RS01510	COG4773	Receptor
A0071_RS01525	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A0071_RS01530	COG0372	Belongs to the citrate synthase family
A0071_RS01535	COG2079	MmgE PrpD family protein
A0071_RS01545	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A0071_RS01550	COG0840	transmembrane signaling receptor activity
A0071_RS01550	COG3290	protein histidine kinase activity
A0071_RS01555	COG0482	sulfurtransferase activity
A0071_RS01560	COG1611	Belongs to the LOG family
A0071_RS01565	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A0071_RS01565	COG1776	CheC inhibitor of MCP methylation
A0071_RS01570	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A0071_RS01575	COG1191	sigma factor activity
A0071_RS01585	COG0455	bacterial-type flagellum organization
A0071_RS01590	COG1419	protein localization to endoplasmic reticulum
A0071_RS01595	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A0071_RS01600	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A0071_RS01605	COG0402	S-adenosylhomocysteine deaminase activity
A0071_RS01630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A0071_RS01630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A0071_RS01645	COG0517	IMP dehydrogenase activity
A0071_RS01645	COG0516	GMP reductase activity
A0071_RS01650	COG0154	amidase activity
A0071_RS01660	COG1058	Belongs to the CinA family
A0071_RS01660	COG1546	Belongs to the CinA family
A0071_RS01665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A0071_RS01670	COG0750	zinc metalloprotease
A0071_RS01675	COG0360	Binds together with S18 to 16S ribosomal RNA
A0071_RS01680	COG0629	single-stranded DNA binding
A0071_RS01685	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A0071_RS01705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A0071_RS01710	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
A0071_RS01720	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A0071_RS01725	COG0753	catalase activity
A0071_RS01785	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A0071_RS01815	COG1077	Cell shape determining protein MreB Mrl
A0071_RS01820	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A0071_RS01825	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A0071_RS01835	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A0071_RS01840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A0071_RS01845	COG1942	4-Oxalocrotonate Tautomerase
A0071_RS01905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A0071_RS01920	COG0477	Major facilitator Superfamily
A0071_RS01935	COG2921	Belongs to the UPF0250 family
A0071_RS01945	COG3290	protein histidine kinase activity
A0071_RS01945	COG0840	transmembrane signaling receptor activity
A0071_RS01950	COG1194	a g-specific adenine glycosylase
A0071_RS01955	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A0071_RS01960	COG2315	Protein conserved in bacteria
A0071_RS01975	COG0477	Major facilitator Superfamily
A0071_RS01980	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A0071_RS01985	COG1253	flavin adenine dinucleotide binding
A0071_RS01990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A0071_RS01995	COG1120	ATPase activity
A0071_RS02000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0071_RS02005	COG4771	TonB-dependent receptor
A0071_RS02010	COG0748	coenzyme F420 binding
A0071_RS02020	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A0071_RS02040	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A0071_RS02050	COG0815	Transfers the fatty acyl group on membrane lipoproteins
A0071_RS02055	COG1862	Preprotein translocase
A0071_RS02060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A0071_RS02065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A0071_RS02085	COG0285	dihydrofolate synthase activity
A0071_RS02090	COG0739	heme binding
A0071_RS02100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A0071_RS02125	COG1840	ABC-type Fe3 transport system, periplasmic component
A0071_RS02130	COG1178	ABC-type Fe3 transport system permease component
A0071_RS02135	COG3842	ATPase activity
A0071_RS02220	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A0071_RS02230	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A0071_RS02240	COG0083	homoserine kinase activity
A0071_RS02265	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A0071_RS02270	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A0071_RS02280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A0071_RS02290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A0071_RS02295	COG2226	methyltransferase
A0071_RS02310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A0071_RS02320	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A0071_RS02345	COG0019	diaminopimelate decarboxylase activity
A0071_RS02365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A0071_RS02375	COG0835	chemotaxis
A0071_RS02380	COG0784	Response regulator, receiver
A0071_RS02380	COG2198	Histidine kinase
A0071_RS02380	COG0643	Histidine kinase
A0071_RS02385	COG0835	chemotaxis
A0071_RS02385	COG0784	Response regulator, receiver
A0071_RS02480	COG2194	sulfuric ester hydrolase activity
A0071_RS02485	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
A0071_RS02505	COG4106	trans-aconitate 2-methyltransferase activity
A0071_RS02510	COG2830	Protein of unknown function (DUF452)
A0071_RS02525	COG0069	glutamate synthase activity
A0071_RS02525	COG0070	glutamate synthase
A0071_RS02525	COG0067	glutamate synthase
A0071_RS02535	COG4953	penicillin-binding protein 1C
A0071_RS02540	COG2373	Large extracellular alpha-helical protein
A0071_RS02550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A0071_RS02565	COG0456	acetyltransferase
A0071_RS02580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A0071_RS02600	COG0463	Glycosyl transferase, family 2
A0071_RS02610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A0071_RS02615	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A0071_RS02620	COG0564	pseudouridine synthase activity
A0071_RS02630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A0071_RS02640	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A0071_RS02655	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A0071_RS02660	COG1187	pseudouridine synthase activity
A0071_RS02665	COG3290	protein histidine kinase activity
A0071_RS02665	COG0840	transmembrane signaling receptor activity
A0071_RS02670	COG0428	transporter
A0071_RS02680	COG0252	asparaginase activity
A0071_RS02685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A0071_RS02700	COG3839	Belongs to the ABC transporter superfamily
A0071_RS02705	COG4662	Binding-protein-dependent transport system inner membrane component
A0071_RS02710	COG2998	abc-type tungstate transport system, permease component
A0071_RS02720	COG2890	protein-(glutamine-N5) methyltransferase activity
A0071_RS02730	COG2249	NAD(P)H dehydrogenase (quinone) activity
A0071_RS02735	COG1064	alcohol dehydrogenase
A0071_RS02755	COG0667	Aldo Keto reductase
A0071_RS02770	COG0656	L-ascorbic acid biosynthetic process
A0071_RS02785	COG0300	oxidoreductase activity
A0071_RS02800	COG0656	L-ascorbic acid biosynthetic process
A0071_RS02810	COG0656	L-ascorbic acid biosynthetic process
A0071_RS02815	COG0789	Transcriptional regulator
A0071_RS02860	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A0071_RS02865	COG0592	DNA-directed DNA polymerase activity
A0071_RS02870	COG0187	DNA topoisomerase II activity
A0071_RS02885	COG3083	sulfuric ester hydrolase activity
A0071_RS02890	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
A0071_RS02905	COG0051	transcription antitermination factor activity, RNA binding
A0071_RS02910	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A0071_RS02915	COG0088	Forms part of the polypeptide exit tunnel
A0071_RS02920	COG0089	rRNA binding
A0071_RS02930	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A0071_RS02940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A0071_RS02945	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A0071_RS02950	COG0255	Belongs to the universal ribosomal protein uL29 family
A0071_RS02955	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A0071_RS02960	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A0071_RS02970	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A0071_RS02975	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A0071_RS02980	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A0071_RS02985	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A0071_RS02990	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A0071_RS02995	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A0071_RS03000	COG0200	Binds to the 23S rRNA
A0071_RS03005	COG0201	protein transport
A0071_RS03035	COG0129	dihydroxy-acid dehydratase activity
A0071_RS03040	COG1858	cytochrome C peroxidase
A0071_RS03045	COG0840	transmembrane signaling receptor activity
A0071_RS03050	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A0071_RS03060	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
A0071_RS03065	COG2873	o-acetylhomoserine
A0071_RS03070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A0071_RS03090	COG2076	Multidrug Resistance protein
A0071_RS03095	COG2076	Multidrug Resistance protein
A0071_RS03100	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A0071_RS03105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A0071_RS03115	COG0783	Belongs to the Dps family
A0071_RS03120	COG0166	Belongs to the GPI family
A0071_RS03130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A0071_RS03160	COG1459	type II secretion system
A0071_RS03165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A0071_RS03190	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A0071_RS03190	COG1013	pyruvate-flavodoxin oxidoreductase activity
A0071_RS03190	COG0674	pyruvate-flavodoxin oxidoreductase activity
A0071_RS03190	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A0071_RS03205	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A0071_RS03210	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A0071_RS03215	COG0450	alkyl hydroperoxide reductase
A0071_RS03225	COG0105	UTP biosynthetic process
A0071_RS03235	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A0071_RS03240	COG0416	fatty acid biosynthetic process
A0071_RS03245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A0071_RS03250	COG0024	Methionine aminopeptidase
A0071_RS03255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A0071_RS03260	COG0791	NLP P60 protein
A0071_RS03265	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A0071_RS03270	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A0071_RS03280	COG1157	protein secretion by the type III secretion system
A0071_RS03285	COG0302	gtp cyclohydrolase
A0071_RS03300	COG0242	peptide deformylase activity
A0071_RS03315	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A0071_RS03315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A0071_RS03320	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A0071_RS03345	COG0575	Belongs to the CDS family
A0071_RS03350	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A0071_RS03360	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A0071_RS03365	COG2165	general secretion pathway protein
A0071_RS03410	COG1815	bacterial-type flagellum-dependent cell motility
A0071_RS03415	COG1558	bacterial-type flagellum-dependent cell motility
A0071_RS03420	COG1677	Flagellar hook-basal body complex protein FliE
A0071_RS03425	COG0768	penicillin binding
A0071_RS03545	COG3409	Peptidoglycan-binding domain 1 protein
A0071_RS03545	COG3501	Rhs element vgr protein
A0071_RS03635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A0071_RS03670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A0071_RS03695	COG0579	oxidoreductase
A0071_RS03700	COG0469	pyruvate kinase activity
A0071_RS03705	COG0140	phosphoribosyl-ATP diphosphatase activity
A0071_RS03705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A0071_RS03715	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A0071_RS03775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A0071_RS03775	COG0131	Imidazoleglycerol-phosphate dehydratase
A0071_RS03790	COG4615	Cyclic peptide transporter
A0071_RS03795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0071_RS03800	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A0071_RS03805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A0071_RS03825	COG0202	RNA polymerase activity
A0071_RS03830	COG0203	ribosomal protein L17
A0071_RS03850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0071_RS03860	COG4172	Belongs to the ABC transporter superfamily
A0071_RS03865	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0071_RS03875	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0071_RS03900	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A0071_RS03910	COG0839	Belongs to the complex I subunit 6 family
A0071_RS03920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A0071_RS03925	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0071_RS03940	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A0071_RS03960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A0071_RS03965	COG0602	queuosine metabolic process
A0071_RS03985	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A0071_RS03990	COG0254	rRNA binding
A0071_RS03995	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A0071_RS04000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A0071_RS04015	COG0436	Aminotransferase
A0071_RS04020	COG0460	homoserine dehydrogenase
A0071_RS04025	COG0792	nuclease activity
A0071_RS04040	COG0148	phosphopyruvate hydratase activity
A0071_RS04045	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A0071_RS04055	COG1987	bacterial-type flagellum assembly
A0071_RS04095	COG0765	amino acid transport
A0071_RS04105	COG2346	COG2346, Truncated hemoglobins
A0071_RS04110	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A0071_RS04115	COG0612	Peptidase, M16
A0071_RS04120	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
A0071_RS04275	COG2856	Zn peptidase
A0071_RS04295	COG0358	DNA primase activity
A0071_RS04330	COG0582	viral genome integration into host DNA
A0071_RS04365	COG0848	biopolymer transport protein
A0071_RS04370	COG0811	peptide transport
A0071_RS04380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A0071_RS04395	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A0071_RS04400	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A0071_RS04405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A0071_RS04425	COG0326	Molecular chaperone. Has ATPase activity
A0071_RS04430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A0071_RS04435	COG0204	Acyl-transferase
A0071_RS04445	COG0047	phosphoribosylformylglycinamidine synthase activity
A0071_RS04450	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A0071_RS04455	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A0071_RS04460	COG0793	Belongs to the peptidase S41A family
A0071_RS04465	COG1937	Protein conserved in bacteria
A0071_RS04470	COG0542	response to heat
A0071_RS04530	COG1074	ATP-dependent DNA helicase activity
A0071_RS04535	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A0071_RS04540	COG1360	Flagellar Motor Protein
A0071_RS04545	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A0071_RS04555	COG1238	metal cluster binding
A0071_RS04565	COG0861	Integral membrane protein TerC family
A0071_RS04600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A0071_RS04605	COG0730	response to heat
A0071_RS04635	COG3951	Flagellar rod assembly protein muramidase FlgJ
A0071_RS04680	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A0071_RS04685	COG0585	pseudouridine synthase activity
A0071_RS04690	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
A0071_RS04700	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A0071_RS04705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A0071_RS04715	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A0071_RS04720	COG0475	glutathione-regulated potassium exporter activity
A0071_RS04720	COG0569	domain protein
A0071_RS04725	COG0372	Belongs to the citrate synthase family
A0071_RS04730	COG1218	3'(2'),5'-bisphosphate nucleotidase
A0071_RS04755	COG0142	geranyltranstransferase activity
A0071_RS04765	COG0442	prolyl-tRNA aminoacylation
A0071_RS04780	COG0181	hydroxymethylbilane synthase activity
A0071_RS04785	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A0071_RS04795	COG1749	Flagellar hook protein flgE
A0071_RS04800	COG0672	)-iron permease
A0071_RS04820	COG1136	(ABC) transporter
A0071_RS04820	COG0577	efflux transmembrane transporter activity
A0071_RS04825	COG1136	(ABC) transporter
A0071_RS04825	COG0577	efflux transmembrane transporter activity
A0071_RS04860	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A0071_RS04865	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A0071_RS04870	COG2176	DNA-directed DNA polymerase activity
A0071_RS04875	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A0071_RS04895	COG2121	Domain of unknown function (DUF374)
A0071_RS04910	COG0195	Participates in both transcription termination and antitermination
A0071_RS04940	COG0739	heme binding
A0071_RS04945	COG0751	glycine-tRNA ligase activity
A0071_RS04965	COG0789	Transcriptional regulator
A0071_RS04970	COG0484	heat shock protein binding
A0071_RS04975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A0071_RS04980	COG0745	RESPONSE REGULATOR receiver
A0071_RS04985	COG0642	Histidine kinase
A0071_RS05030	COG3177	Filamentation induced by cAMP protein fic
A0071_RS05170	COG2856	Zn peptidase
A0071_RS05185	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A0071_RS05190	COG0731	radical SAM domain protein
A0071_RS05225	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A0071_RS05240	COG0037	tRNA processing
A0071_RS05245	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A0071_RS05250	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A0071_RS05255	COG1047	Peptidyl-prolyl cis-trans
A0071_RS05265	COG2885	chlorophyll binding
A0071_RS05280	COG0848	biopolymer transport protein
A0071_RS05285	COG0811	peptide transport
A0071_RS05290	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A0071_RS05295	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A0071_RS05315	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A0071_RS05320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A0071_RS05325	COG1475	DNA binding
A0071_RS05330	COG1192	Involved in chromosome partitioning
A0071_RS05380	COG1739	Uncharacterized protein family UPF0029
A0071_RS05405	COG1053	succinate dehydrogenase
A0071_RS05410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A0071_RS05430	COG0628	permease
A0071_RS05450	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A0071_RS05465	COG1160	GTP binding
A0071_RS05480	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A0071_RS05485	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A0071_RS05490	COG0284	orotidine-5'-phosphate decarboxylase activity
A0071_RS05525	COG1193	negative regulation of DNA recombination
A0071_RS05545	COG0840	transmembrane signaling receptor activity
A0071_RS05550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A0071_RS05555	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
A0071_RS05560	COG0281	malic enzyme
A0071_RS05565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A0071_RS05575	COG0439	Biotin carboxylase
A0071_RS05595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A0071_RS05600	COG0569	domain protein
A0071_RS05605	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
A0071_RS05610	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A0071_RS05635	COG0799	negative regulation of ribosome biogenesis
A0071_RS05640	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A0071_RS05655	COG1580	Controls the rotational direction of flagella during chemotaxis
A0071_RS05680	COG1126	abc transporter atp-binding protein
A0071_RS05685	COG0765	amino acid transport
A0071_RS05690	COG0765	amino acid transport
A0071_RS05695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A0071_RS05700	COG1126	abc transporter atp-binding protein
A0071_RS05705	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A0071_RS05710	COG2201	protein-glutamate methylesterase activity
A0071_RS05735	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A0071_RS05740	COG0012	GTP binding
A0071_RS05745	COG0204	Acyl-transferase
A0071_RS05745	COG0318	PFAM AMP-dependent synthetase and ligase
A0071_RS05800	COG0727	PFAM Uncharacterised protein family (UPF0153)
A0071_RS05805	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A0071_RS05815	COG0179	Fumarylacetoacetate (FAA) hydrolase
A0071_RS05820	COG0668	transmembrane transport
A0071_RS05825	COG0288	reversible hydration of carbon dioxide
A0071_RS05830	COG0670	Belongs to the BI1 family
A0071_RS05835	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A0071_RS05840	COG0233	cytoplasmic translational termination
A0071_RS05855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A0071_RS05870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A0071_RS05890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A0071_RS05910	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A0071_RS05915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A0071_RS05920	COG0191	fructose-bisphosphate aldolase activity
A0071_RS05935	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A0071_RS05935	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A0071_RS05950	COG1086	Polysaccharide biosynthesis protein
A0071_RS05955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A0071_RS05975	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A0071_RS05990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A0071_RS05995	COG1083	cytidylyl-transferase
A0071_RS06005	COG0066	3-isopropylmalate dehydratase activity
A0071_RS06015	COG0473	3-isopropylmalate dehydrogenase activity
A0071_RS06045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A0071_RS06050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A0071_RS06065	COG0250	Participates in transcription elongation, termination and antitermination
A0071_RS06070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A0071_RS06075	COG0081	regulation of translation
A0071_RS06085	COG0222	ribosome binding
A0071_RS06090	COG0085	RNA polymerase activity
A0071_RS06100	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A0071_RS06110	COG0049	tRNA binding
A0071_RS06145	COG0004	ammonium transporteR
A0071_RS06165	COG4773	Receptor
A0071_RS06175	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A0071_RS06175	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A0071_RS06185	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A0071_RS06200	COG2217	Heavy metal translocating P-type atpase
A0071_RS06205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A0071_RS06210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A0071_RS06235	COG1301	dicarboxylic acid transport
A0071_RS06255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A0071_RS06260	COG0723	plastoquinol--plastocyanin reductase activity
A0071_RS06265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A0071_RS06280	COG1027	Aspartate ammonia-lyase
A0071_RS06285	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A0071_RS06305	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A0071_RS06310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A0071_RS06325	COG0529	Catalyzes the synthesis of activated sulfate
A0071_RS06340	COG0768	penicillin binding
A0071_RS06370	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A0071_RS06380	COG0084	hydrolase, TatD family'
A0071_RS06390	COG0497	DNA recombination
A0071_RS06400	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A0071_RS06410	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A0071_RS06465	COG3736	Type IV secretory pathway, component VirB8
A0071_RS06485	COG2814	Major facilitator Superfamily
A0071_RS06505	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A0071_RS06520	COG0840	transmembrane signaling receptor activity
A0071_RS06525	COG0138	bifunctional purine biosynthesis protein purh
A0071_RS06530	COG0484	heat shock protein binding
A0071_RS06540	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A0071_RS06550	COG0706	membrane insertase activity
A0071_RS06560	COG0594	ribonuclease P activity
A0071_RS06565	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A0071_RS06580	COG0824	Thioesterase
A0071_RS06595	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A0071_RS06605	COG0500	methyltransferase
A0071_RS06625	COG2195	Cleaves the N-terminal amino acid of tripeptides
A0071_RS06630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A0071_RS06640	COG3022	response to hydroperoxide
A0071_RS06655	COG2181	nitrate reductase activity
A0071_RS06655	COG0247	lactate metabolic process
A0071_RS06670	COG2992	FlgJ-related protein
A0071_RS06675	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A0071_RS06690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0071_RS06695	COG2095	MarC family integral membrane protein
A0071_RS06705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A0071_RS06715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A0071_RS06720	COG0113	porphobilinogen synthase activity
A0071_RS06725	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A0071_RS06730	COG0357	Ribosomal RNA small subunit methyltransferase G
A0071_RS06745	COG2860	membrane
A0071_RS06775	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A0071_RS06775	COG0517	IMP dehydrogenase activity
A0071_RS06785	COG1215	transferase activity, transferring glycosyl groups
A0071_RS06785	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A0071_RS06790	COG0471	metal ion transport
A0071_RS06820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A0071_RS06845	COG1921	L-seryl-tRNASec selenium transferase activity
A0071_RS06855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A0071_RS06860	COG0280	phosphate acetyltransferase
A0071_RS06900	COG1181	Belongs to the D-alanine--D-alanine ligase family
A0071_RS06905	COG0632	four-way junction helicase activity
A0071_RS06915	COG0728	peptidoglycan biosynthetic process
A0071_RS06920	COG0215	cysteine-tRNA ligase activity
A0071_RS06925	COG1132	(ABC) transporter
A0071_RS06930	COG0167	dihydroorotate dehydrogenase activity
A0071_RS06935	COG0612	Peptidase, M16
A0071_RS06945	COG1028	Short-chain dehydrogenase reductase Sdr
A0071_RS06970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A0071_RS06975	COG1663	tetraacyldisaccharide 4'-kinase activity
A0071_RS06980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A0071_RS06995	COG1338	Plays a role in the flagellum-specific transport system
A0071_RS07030	COG0101	tRNA pseudouridine synthase activity
A0071_RS07035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A0071_RS07055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A0071_RS07060	COG4221	oxidoreductase activity
A0071_RS07070	COG1049	propionate catabolic process, 2-methylcitrate cycle
A0071_RS07095	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A0071_RS07105	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A0071_RS07115	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A0071_RS07120	COG0653	protein targeting
A0071_RS07125	COG4591	ABC-type transport system involved in lipoprotein release permease component
A0071_RS07165	COG0800	Aldolase
A0071_RS07170	COG0129	dihydroxy-acid dehydratase activity
A0071_RS07175	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A0071_RS07180	COG0363	glucosamine-6-phosphate deaminase activity
A0071_RS07195	COG0738	Major facilitator superfamily
A0071_RS07200	COG0174	glutamine synthetase
A0071_RS07210	COG0826	peptidase U32
A0071_RS07215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A0071_RS07230	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A0071_RS07240	COG1519	Transferase
A0071_RS07245	COG0564	pseudouridine synthase activity
A0071_RS07250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A0071_RS07255	COG0228	four-way junction DNA binding
A0071_RS07270	COG0336	Belongs to the RNA methyltransferase TrmD family
A0071_RS07280	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
A0071_RS07285	COG1393	Belongs to the ArsC family
A0071_RS07295	COG0805	protein transport
A0071_RS07310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A0071_RS07315	COG0494	nUDIX hydrolase
A0071_RS07320	COG0527	aspartate kinase activity
A0071_RS07335	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A0071_RS07340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A0071_RS07350	COG0196	riboflavin kinase activity
A0071_RS07365	COG1970	mechanosensitive ion channel activity
A0071_RS07380	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A0071_RS07385	COG0210	DNA helicase
A0071_RS07400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A0071_RS07405	COG2011	ABC-type metal ion transport system permease component
A0071_RS07410	COG1464	Belongs to the NlpA lipoprotein family
A0071_RS07415	COG1464	Belongs to the NlpA lipoprotein family
A0071_RS07420	COG1464	Belongs to the NlpA lipoprotein family
A0071_RS07430	COG0163	prenyltransferase activity
A0071_RS07435	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A0071_RS07450	COG1166	arginine decarboxylase activity
A0071_RS07455	COG1045	serine acetyltransferase
A0071_RS07500	COG0537	adenosine 5'-monophosphoramidase activity
A0071_RS07505	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A0071_RS07515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A0071_RS07520	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A0071_RS07525	COG0539	negative regulation of cytoplasmic translation
A0071_RS07525	COG1185	polyribonucleotide nucleotidyltransferase activity
A0071_RS07535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A0071_RS07545	COG2202	Pas domain
A0071_RS07545	COG2205	protein histidine kinase activity
A0071_RS07550	COG0488	(ABC) transporter
A0071_RS07585	COG0501	Belongs to the peptidase M48B family
A0071_RS07590	COG2890	protein-(glutamine-N5) methyltransferase activity
A0071_RS07605	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A0071_RS07630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A0071_RS07645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A0071_RS07675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A0071_RS07680	COG4786	Flagellar basal body rod
A0071_RS07685	COG4786	Flagellar basal body rod
A0071_RS07695	COG0437	4 iron, 4 sulfur cluster binding
A0071_RS07700	COG0348	domain, Protein
A0071_RS07705	COG3043	anaerobic respiration
A0071_RS07725	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A0071_RS07745	COG0617	tRNA 3'-terminal CCA addition
A0071_RS07750	COG0788	formyltetrahydrofolate deformylase activity
A0071_RS07755	COG0598	Magnesium transport protein CorA
A0071_RS07760	COG0521	Mo-molybdopterin cofactor biosynthetic process
A0071_RS07770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A0071_RS07775	COG1674	ftsk spoiiie
A0071_RS07775	COG1196	nuclear chromosome segregation
A0071_RS07810	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A0071_RS07820	COG0582	viral genome integration into host DNA
A0071_RS07830	COG0512	Glutamine amidotransferase of anthranilate synthase
A0071_RS07830	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A0071_RS07840	COG2404	hydrolase activity, acting on ester bonds
A0071_RS07845	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A0071_RS07850	COG1959	2 iron, 2 sulfur cluster binding
A0071_RS07855	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A0071_RS07865	COG0303	'Molybdopterin
A0071_RS07885	COG0681	Belongs to the peptidase S26 family
A0071_RS07900	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A0071_RS07925	COG2257	FlhB HrpN YscU SpaS Family
A0071_RS08000	COG0243	molybdopterin cofactor binding
A0071_RS08005	COG0688	phosphatidylethanolamine metabolic process
A0071_RS08010	COG1408	metallophosphoesterase
A0071_RS08015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A0071_RS08035	COG0552	protein localization to endoplasmic reticulum
A0071_RS08040	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
A0071_RS08050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0071_RS08050	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0071_RS08070	COG0642	Histidine kinase
A0071_RS08075	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
A0071_RS08080	COG0542	response to heat
A0071_RS08100	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A0071_RS08110	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A0071_RS08115	COG0210	DNA helicase
A0071_RS08135	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A0071_RS08145	COG1013	pyruvate-flavodoxin oxidoreductase activity
A0071_RS08150	COG0674	pyruvate-flavodoxin oxidoreductase activity
A0071_RS08150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A0071_RS08160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A0071_RS08165	COG0045	succinate-CoA ligase (ADP-forming) activity
A0071_RS08170	COG0039	L-malate dehydrogenase activity
A0071_RS08190	COG0587	DNA-directed DNA polymerase activity
A0071_RS08210	COG1115	amino acid carrier protein
A0071_RS08220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A0071_RS08225	COG3034	peptidoglycan biosynthetic process
A0071_RS08240	COG1999	signal sequence binding
A0071_RS08245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A0071_RS08250	COG0776	regulation of translation
A0071_RS08260	COG1607	acyl-coa hydrolase
A0071_RS08265	COG2879	small protein
A0071_RS08270	COG1966	Carbon starvation protein
A0071_RS08275	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A0071_RS08280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A0071_RS08285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A0071_RS08290	COG0765	amino acid transport
A0071_RS08295	COG0709	Synthesizes selenophosphate from selenide and ATP
A0071_RS08300	COG0251	oxidation-reduction process
A0071_RS08305	COG2391	methyltransferase activity
A0071_RS08310	COG0425	Belongs to the sulfur carrier protein TusA family
A0071_RS08385	COG0786	glutamate:sodium symporter activity
A0071_RS08395	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A0071_RS08435	COG0642	Histidine kinase
A0071_RS08440	COG0745	RESPONSE REGULATOR receiver
A0071_RS08490	COG3118	belongs to the thioredoxin family
A0071_RS08495	COG0492	ferredoxin-NADP+ reductase activity
A0071_RS08500	COG2814	Major facilitator Superfamily
A0071_RS08510	COG0352	thiamine-phosphate diphosphorylase activity
A0071_RS08515	COG0351	phosphomethylpyrimidine kinase
A0071_RS08515	COG0352	thiamine-phosphate diphosphorylase activity
A0071_RS08530	COG2171	N-acyltransferase activity
A0071_RS08535	COG0489	protein tyrosine kinase activity
A0071_RS08540	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A0071_RS08540	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A0071_RS08545	COG0745	RESPONSE REGULATOR receiver
A0071_RS08550	COG2046	Belongs to the sulfate adenylyltransferase family
A0071_RS08555	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A0071_RS08560	COG0268	Binds directly to 16S ribosomal RNA
A0071_RS08565	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A0071_RS08570	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A0071_RS08585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A0071_RS08590	COG0577	efflux transmembrane transporter activity
A0071_RS08590	COG1136	(ABC) transporter
A0071_RS08595	COG1538	Outer membrane efflux protein
A0071_RS08610	COG1696	Membrane protein involved in D-alanine export
A0071_RS08615	COG1528	Iron-storage protein
A0071_RS08630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0071_RS08635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0071_RS08655	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
A0071_RS08680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0071_RS08740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A0071_RS08745	COG1132	(ABC) transporter
A0071_RS08750	COG0438	transferase activity, transferring glycosyl groups
A0071_RS08755	COG1215	transferase activity, transferring glycosyl groups
A0071_RS08760	COG0438	transferase activity, transferring glycosyl groups
A0071_RS08770	COG0438	transferase activity, transferring glycosyl groups
A0071_RS08775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A0071_RS08780	COG0110	maltose O-acetyltransferase activity
A0071_RS08785	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A0071_RS08790	COG1086	Polysaccharide biosynthesis protein
A0071_RS08795	COG0745	RESPONSE REGULATOR receiver
A0071_RS08805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A0071_RS08815	COG1183	phosphatidylcholine synthase activity
A0071_RS08820	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A0071_RS08825	COG0352	thiamine-phosphate diphosphorylase activity
A0071_RS08835	COG0006	proline dipeptidase activity
A0071_RS08855	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A0071_RS08860	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A0071_RS08875	COG0137	argininosuccinate synthase activity
A0071_RS08885	COG0277	FAD linked oxidase domain protein
A0071_RS08895	COG0739	heme binding
A0071_RS08900	COG2217	Heavy metal translocating P-type atpase
A0071_RS08915	COG0217	transcriptional regulatory protein
A0071_RS08920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A0071_RS08940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A0071_RS08945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A0071_RS08950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A0071_RS08965	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A0071_RS08970	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A0071_RS09035	COG0849	cell division
A0071_RS09040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A0071_RS09055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A0071_RS09060	COG0626	cystathionine gamma-synthase activity
A0071_RS09075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0071_RS09090	COG3177	Filamentation induced by cAMP protein fic
A0071_RS09170	COG0439	Biotin carboxylase
A0071_RS09175	COG0772	Belongs to the SEDS family
A0071_RS09190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A0071_RS09190	COG1333	cytochrome c biogenesis protein
A0071_RS09235	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A0071_RS09240	COG2204	response regulator
A0071_RS09280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A0071_RS09295	COG0471	metal ion transport
A0071_RS09300	COG0481	GTPase activity
A0071_RS09315	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
A0071_RS09320	COG2249	NAD(P)H dehydrogenase (quinone) activity
A0071_RS09335	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
A0071_RS09340	COG3005	denitrification pathway
A0071_RS09345	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A0071_RS09350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A0071_RS09380	COG0745	RESPONSE REGULATOR receiver
A0071_RS09385	COG0642	Histidine kinase
A0071_RS09395	COG0459	protein refolding
A0071_RS09400	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A0071_RS09415	COG1496	oxidoreductase activity
A0071_RS09430	COG1213	nucleotidyl transferase
A0071_RS09435	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A0071_RS09440	COG0574	Belongs to the PEP-utilizing enzyme family
A0071_RS09440	COG3848	Pyruvate phosphate dikinase
A0071_RS09455	COG0586	Pfam SNARE associated Golgi protein
A0071_RS09485	COG1473	amidohydrolase
A0071_RS09490	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
A0071_RS09510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A0071_RS09535	COG4771	TonB-dependent receptor
A0071_RS09540	COG0778	Nitroreductase
A0071_RS09545	COG0778	Nitroreductase
A0071_RS09550	COG1289	transmembrane transporter activity
A0071_RS09555	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A0071_RS09560	COG0492	ferredoxin-NADP+ reductase activity