locus-tag	class	description
CHHT_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CHHT_RS00010	COG0592	DNA-directed DNA polymerase activity
CHHT_RS00015	COG0187	DNA topoisomerase II activity
CHHT_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CHHT_RS00050	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CHHT_RS00075	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CHHT_RS00100	COG0438	transferase activity, transferring glycosyl groups
CHHT_RS00105	COG3842	ATPase activity
CHHT_RS00110	COG1454	alcohol dehydrogenase
CHHT_RS00120	COG2226	methyltransferase
CHHT_RS00130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CHHT_RS00140	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CHHT_RS00145	COG2089	acid synthase
CHHT_RS00150	COG4310	Domain of unknown function (DUF2172)
CHHT_RS00190	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CHHT_RS00205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHHT_RS00225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHHT_RS00230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHHT_RS00275	COG2226	methyltransferase
CHHT_RS00295	COG0463	Glycosyl transferase, family 2
CHHT_RS00295	COG1216	Glycosyl transferase, family 2
CHHT_RS00315	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHHT_RS00345	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHHT_RS00360	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CHHT_RS00380	COG4624	Iron only hydrogenase large subunit, C-terminal domain
CHHT_RS00380	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHHT_RS00390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CHHT_RS00395	COG0051	transcription antitermination factor activity, RNA binding
CHHT_RS00400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CHHT_RS00405	COG0088	Forms part of the polypeptide exit tunnel
CHHT_RS00410	COG0089	rRNA binding
CHHT_RS00415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CHHT_RS00420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHHT_RS00425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CHHT_RS00430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CHHT_RS00435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CHHT_RS00445	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CHHT_RS00450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CHHT_RS00455	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CHHT_RS00465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CHHT_RS00470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CHHT_RS00475	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CHHT_RS00480	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CHHT_RS00485	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CHHT_RS00490	COG0200	Binds to the 23S rRNA
CHHT_RS00495	COG0201	protein transport
CHHT_RS00500	COG0024	Methionine aminopeptidase
CHHT_RS00510	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CHHT_RS00515	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CHHT_RS00520	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CHHT_RS00525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CHHT_RS00530	COG0202	RNA polymerase activity
CHHT_RS00535	COG0203	ribosomal protein L17
CHHT_RS00550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CHHT_RS00555	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CHHT_RS00560	COG0840	transmembrane signaling receptor activity
CHHT_RS00565	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CHHT_RS00580	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CHHT_RS00585	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CHHT_RS00590	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CHHT_RS00595	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CHHT_RS00600	COG1840	ABC-type Fe3 transport system, periplasmic component
CHHT_RS00625	COG1309	transcriptional regulator
CHHT_RS00630	COG0348	domain, Protein
CHHT_RS00635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHHT_RS00650	COG3260	NADH ubiquinone oxidoreductase 20
CHHT_RS00655	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHHT_RS00660	COG3261	NADH dehydrogenase
CHHT_RS00660	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CHHT_RS00665	COG0651	ATP synthesis coupled electron transport
CHHT_RS00670	COG4237	Hydrogenase 4 membrane
CHHT_RS00675	COG0650	Formate hydrogenlyase subunit 4
CHHT_RS00680	COG0651	ATP synthesis coupled electron transport
CHHT_RS00685	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHHT_RS00700	COG1053	succinate dehydrogenase
CHHT_RS00700	COG3976	FMN-binding domain protein
CHHT_RS00715	COG4191	Histidine kinase
CHHT_RS00720	COG0745	RESPONSE REGULATOR receiver
CHHT_RS00755	COG0501	Belongs to the peptidase M48B family
CHHT_RS00760	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CHHT_RS00765	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CHHT_RS00770	COG1253	flavin adenine dinucleotide binding
CHHT_RS00800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHHT_RS00805	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CHHT_RS00810	COG0475	glutathione-regulated potassium exporter activity
CHHT_RS00810	COG0569	domain protein
CHHT_RS00815	COG0372	Belongs to the citrate synthase family
CHHT_RS00825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CHHT_RS00830	COG0573	inorganic phosphate transmembrane transporter activity
CHHT_RS00840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHHT_RS00850	COG2814	Major facilitator Superfamily
CHHT_RS00855	COG0840	transmembrane signaling receptor activity
CHHT_RS00875	COG0456	acetyltransferase
CHHT_RS00875	COG0454	-acetyltransferase
CHHT_RS00880	COG0840	transmembrane signaling receptor activity
CHHT_RS00895	COG0314	molybdopterin synthase activity
CHHT_RS00905	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CHHT_RS00910	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHHT_RS00935	COG0148	phosphopyruvate hydratase activity
CHHT_RS00940	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHHT_RS00945	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CHHT_RS00975	COG0575	Belongs to the CDS family
CHHT_RS00980	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CHHT_RS00995	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CHHT_RS01005	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHHT_RS01025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHHT_RS01030	COG0602	queuosine metabolic process
CHHT_RS01035	COG1979	alcohol dehydrogenase
CHHT_RS01090	COG0450	alkyl hydroperoxide reductase
CHHT_RS01095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CHHT_RS01100	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CHHT_RS01115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHHT_RS01130	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHHT_RS01140	COG0745	RESPONSE REGULATOR receiver
CHHT_RS01150	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CHHT_RS01160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHHT_RS01165	COG0416	fatty acid biosynthetic process
CHHT_RS01170	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CHHT_RS01180	COG0105	UTP biosynthetic process
CHHT_RS01190	COG1360	Flagellar Motor Protein
CHHT_RS01195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CHHT_RS01200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHHT_RS01200	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHHT_RS01235	COG1570	exodeoxyribonuclease VII activity
CHHT_RS01255	COG1131	(ABC) transporter
CHHT_RS01260	COG0842	Transport permease protein
CHHT_RS01265	COG0842	Transport permease protein
CHHT_RS01275	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CHHT_RS01285	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHHT_RS01290	COG1766	The M ring may be actively involved in energy transduction
CHHT_RS01295	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHHT_RS01310	COG0019	diaminopimelate decarboxylase activity
CHHT_RS01325	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CHHT_RS01330	COG4774	siderophore transport
CHHT_RS01340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHHT_RS01355	COG1120	ATPase activity
CHHT_RS01365	COG0811	peptide transport
CHHT_RS01370	COG0848	biopolymer transport protein
CHHT_RS01400	COG0254	rRNA binding
CHHT_RS01405	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CHHT_RS01410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHHT_RS01425	COG0436	Aminotransferase
CHHT_RS01430	COG0460	homoserine dehydrogenase
CHHT_RS01435	COG0792	nuclease activity
CHHT_RS01440	COG3118	belongs to the thioredoxin family
CHHT_RS01445	COG0492	ferredoxin-NADP+ reductase activity
CHHT_RS01455	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CHHT_RS01460	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CHHT_RS01475	COG0140	phosphoribosyl-ATP diphosphatase activity
CHHT_RS01475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CHHT_RS01495	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CHHT_RS01505	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CHHT_RS01535	COG0723	plastoquinol--plastocyanin reductase activity
CHHT_RS01540	COG1279	arginine transmembrane transporter activity
CHHT_RS01545	COG0445	tRNA wobble uridine modification
CHHT_RS01555	COG0863	Belongs to the N(4) N(6)-methyltransferase family
CHHT_RS01570	COG2194	sulfuric ester hydrolase activity
CHHT_RS01590	COG0052	Belongs to the universal ribosomal protein uS2 family
CHHT_RS01595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CHHT_RS01600	COG1136	(ABC) transporter
CHHT_RS01605	COG1684	flagellar biosynthetic protein fliR
CHHT_RS01620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHHT_RS01625	COG0018	arginyl-trna synthetase
CHHT_RS01630	COG0583	DNA-binding transcription factor activity
CHHT_RS01635	COG2855	membrane
CHHT_RS01640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CHHT_RS01650	COG0126	phosphoglycerate kinase activity
CHHT_RS01655	COG0149	triose-phosphate isomerase activity
CHHT_RS01660	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CHHT_RS01680	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CHHT_RS01685	COG0656	L-ascorbic acid biosynthetic process
CHHT_RS01690	COG2217	Heavy metal translocating P-type atpase
CHHT_RS01710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CHHT_RS01720	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CHHT_RS01720	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CHHT_RS01725	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CHHT_RS01730	COG0859	PFAM glycosyl transferase family 9
CHHT_RS01750	COG0438	transferase activity, transferring glycosyl groups
CHHT_RS01755	COG0859	PFAM glycosyl transferase family 9
CHHT_RS01770	COG0726	polysaccharide deacetylase
CHHT_RS01775	COG0859	PFAM glycosyl transferase family 9
CHHT_RS01800	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CHHT_RS01810	COG1793	dna ligase
CHHT_RS01820	COG2814	Major facilitator Superfamily
CHHT_RS01825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHHT_RS01835	COG2244	polysaccharide biosynthetic process
CHHT_RS01840	COG0438	transferase activity, transferring glycosyl groups
CHHT_RS01850	COG0438	transferase activity, transferring glycosyl groups
CHHT_RS01860	COG0438	transferase activity, transferring glycosyl groups
CHHT_RS01865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHHT_RS01870	COG0110	maltose O-acetyltransferase activity
CHHT_RS01880	COG0166	Belongs to the GPI family
CHHT_RS01885	COG0783	Belongs to the Dps family
CHHT_RS01900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CHHT_RS01905	COG4106	trans-aconitate 2-methyltransferase activity
CHHT_RS01925	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CHHT_RS01950	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CHHT_RS01975	COG3951	Flagellar rod assembly protein muramidase FlgJ
CHHT_RS02005	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CHHT_RS02010	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHHT_RS02040	COG0716	FMN binding
CHHT_RS02045	COG0814	amino acid
CHHT_RS02050	COG0217	transcriptional regulatory protein
CHHT_RS02055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CHHT_RS02060	COG1301	dicarboxylic acid transport
CHHT_RS02065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHHT_RS02095	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CHHT_RS02100	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CHHT_RS02135	COG2217	Heavy metal translocating P-type atpase
CHHT_RS02155	COG1053	succinate dehydrogenase
CHHT_RS02160	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CHHT_RS02170	COG1854	S-ribosylhomocysteine lyase activity
CHHT_RS02175	COG1007	ATP synthesis coupled electron transport
CHHT_RS02180	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHHT_RS02185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CHHT_RS02190	COG0713	ATP synthesis coupled electron transport
CHHT_RS02195	COG0839	Belongs to the complex I subunit 6 family
CHHT_RS02200	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHHT_RS02205	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CHHT_RS02210	COG1034	ATP synthesis coupled electron transport
CHHT_RS02215	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CHHT_RS02225	COG0649	NAD binding
CHHT_RS02230	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHHT_RS02235	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHHT_RS02240	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CHHT_RS02255	COG4263	nitrous-oxide reductase activity
CHHT_RS02270	COG0437	4 iron, 4 sulfur cluster binding
CHHT_RS02285	COG0348	domain, Protein
CHHT_RS02290	COG3842	ATPase activity
CHHT_RS02310	COG0824	Thioesterase
CHHT_RS02330	COG0004	ammonium transporteR
CHHT_RS02335	COG0347	Belongs to the P(II) protein family
CHHT_RS02340	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CHHT_RS02345	COG0594	ribonuclease P activity
CHHT_RS02355	COG0706	membrane insertase activity
CHHT_RS02365	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CHHT_RS02370	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHHT_RS02375	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CHHT_RS02380	COG0138	bifunctional purine biosynthesis protein purh
CHHT_RS02395	COG2151	metal-sulfur cluster biosynthetic enzyme
CHHT_RS02400	COG0840	transmembrane signaling receptor activity
CHHT_RS02425	COG0275	rRNA processing
CHHT_RS02440	COG0849	cell division
CHHT_RS02445	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHHT_RS02455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHHT_RS02465	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CHHT_RS02470	COG0653	protein targeting
CHHT_RS02475	COG4591	ABC-type transport system involved in lipoprotein release permease component
CHHT_RS02500	COG2252	PERMEase
CHHT_RS02505	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CHHT_RS02515	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CHHT_RS02530	COG0745	RESPONSE REGULATOR receiver
CHHT_RS02535	COG3301	Polysulphide reductase, NrfD
CHHT_RS02540	COG0437	4 iron, 4 sulfur cluster binding
CHHT_RS02545	COG0243	molybdopterin cofactor binding
CHHT_RS02555	COG0425	Belongs to the sulfur carrier protein TusA family
CHHT_RS02560	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CHHT_RS02565	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CHHT_RS02590	COG1596	polysaccharide export
CHHT_RS02590	COG1555	photosystem II stabilization
CHHT_RS02645	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CHHT_RS02655	COG1058	Belongs to the CinA family
CHHT_RS02655	COG1546	Belongs to the CinA family
CHHT_RS02665	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CHHT_RS02670	COG0154	amidase activity
CHHT_RS02675	COG0516	GMP reductase activity
CHHT_RS02675	COG0517	IMP dehydrogenase activity
CHHT_RS02680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHHT_RS02695	COG1999	signal sequence binding
CHHT_RS02700	COG0772	Belongs to the SEDS family
CHHT_RS02705	COG0564	pseudouridine synthase activity
CHHT_RS02715	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CHHT_RS02720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHHT_RS02735	COG0528	UMP kinase activity
CHHT_RS02740	COG1758	RNA polymerase activity
CHHT_RS02750	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHHT_RS02760	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHHT_RS02765	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CHHT_RS02765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHHT_RS02775	COG0519	Catalyzes the synthesis of GMP from XMP
CHHT_RS02780	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CHHT_RS02785	COG0563	adenylate kinase activity
CHHT_RS02790	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CHHT_RS02800	COG0497	DNA recombination
CHHT_RS02810	COG0084	hydrolase, TatD family'
CHHT_RS02820	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CHHT_RS02825	COG0131	Imidazoleglycerol-phosphate dehydratase
CHHT_RS02845	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CHHT_RS02860	COG0768	penicillin binding
CHHT_RS02865	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHHT_RS02890	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CHHT_RS02900	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CHHT_RS02905	COG0681	Belongs to the peptidase S26 family
CHHT_RS02910	COG1994	Peptidase M50
CHHT_RS02915	COG0698	ribose 5-phosphate isomerase
CHHT_RS02925	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHHT_RS02935	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CHHT_RS02940	COG0012	GTP binding
CHHT_RS02945	COG0243	molybdopterin cofactor binding
CHHT_RS02950	COG0437	4 iron, 4 sulfur cluster binding
CHHT_RS02955	COG0348	domain, Protein
CHHT_RS02960	COG3043	anaerobic respiration
CHHT_RS02980	COG0688	phosphatidylethanolamine metabolic process
CHHT_RS02985	COG1408	metallophosphoesterase
CHHT_RS02990	COG1114	Component of the transport system for branched-chain amino acids
CHHT_RS02995	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CHHT_RS03020	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHHT_RS03040	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CHHT_RS03045	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHHT_RS03060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHHT_RS03070	COG0642	Histidine kinase
CHHT_RS03075	COG0745	RESPONSE REGULATOR receiver
CHHT_RS03080	COG0484	heat shock protein binding
CHHT_RS03085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CHHT_RS03090	COG0629	single-stranded DNA binding
CHHT_RS03095	COG0360	Binds together with S18 to 16S ribosomal RNA
CHHT_RS03105	COG0557	exoribonuclease II activity
CHHT_RS03115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CHHT_RS03120	COG2861	carbohydrate metabolic process
CHHT_RS03125	COG0758	DNA mediated transformation
CHHT_RS03130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CHHT_RS03145	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHHT_RS03150	COG0805	protein transport
CHHT_RS03155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHHT_RS03160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHHT_RS03165	COG0494	nUDIX hydrolase
CHHT_RS03170	COG0527	aspartate kinase activity
CHHT_RS03185	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CHHT_RS03190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CHHT_RS03195	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CHHT_RS03200	COG0196	riboflavin kinase activity
CHHT_RS03205	COG2226	methyltransferase
CHHT_RS03215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHHT_RS03220	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CHHT_RS03225	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CHHT_RS03230	COG1959	2 iron, 2 sulfur cluster binding
CHHT_RS03235	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHHT_RS03240	COG2404	hydrolase activity, acting on ester bonds
CHHT_RS03255	COG1420	regulation of RNA biosynthetic process
CHHT_RS03260	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CHHT_RS03265	COG0443	Heat shock 70 kDa protein
CHHT_RS03285	COG3706	GGDEF domain
CHHT_RS03290	COG2199	diguanylate cyclase activity
CHHT_RS03290	COG2203	Gaf domain
CHHT_RS03305	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CHHT_RS03310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CHHT_RS03315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CHHT_RS03320	COG1663	tetraacyldisaccharide 4'-kinase activity
CHHT_RS03330	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CHHT_RS03335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHHT_RS03345	COG0500	methyltransferase
CHHT_RS03355	COG2195	Cleaves the N-terminal amino acid of tripeptides
CHHT_RS03380	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CHHT_RS03385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHHT_RS03390	COG0577	efflux transmembrane transporter activity
CHHT_RS03390	COG1136	(ABC) transporter
CHHT_RS03395	COG1538	Outer membrane efflux protein
CHHT_RS03405	COG0642	Histidine kinase
CHHT_RS03410	COG0745	RESPONSE REGULATOR receiver
CHHT_RS03420	COG0484	heat shock protein binding
CHHT_RS03425	COG0789	Transcriptional regulator
CHHT_RS03435	COG3263	regulation of cellular component size
CHHT_RS03440	COG0730	response to heat
CHHT_RS03445	COG0356	it plays a direct role in the translocation of protons across the membrane
CHHT_RS03450	COG0352	thiamine-phosphate diphosphorylase activity
CHHT_RS03455	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHHT_RS03460	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CHHT_RS03475	COG2962	Rard protein
CHHT_RS03480	COG1126	abc transporter atp-binding protein
CHHT_RS03485	COG0765	amino acid transport
CHHT_RS03490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHHT_RS03495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHHT_RS03500	COG1028	Short-chain dehydrogenase reductase Sdr
CHHT_RS03505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHHT_RS03510	COG0612	Peptidase, M16
CHHT_RS03515	COG0167	dihydroorotate dehydrogenase activity
CHHT_RS03520	COG1132	(ABC) transporter
CHHT_RS03525	COG0215	cysteine-tRNA ligase activity
CHHT_RS03530	COG0728	peptidoglycan biosynthetic process
CHHT_RS03535	COG0513	Belongs to the DEAD box helicase family
CHHT_RS03550	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CHHT_RS03560	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHHT_RS03560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHHT_RS03600	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CHHT_RS03615	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CHHT_RS03620	COG2201	protein-glutamate methylesterase activity
CHHT_RS03630	COG0632	four-way junction helicase activity
CHHT_RS03635	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHHT_RS03650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHHT_RS03665	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CHHT_RS03670	COG0280	phosphate acetyltransferase
CHHT_RS03675	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CHHT_RS03680	COG0028	Belongs to the TPP enzyme family
CHHT_RS03685	COG0440	acetolactate synthase activity
CHHT_RS03695	COG0586	Pfam SNARE associated Golgi protein
CHHT_RS03705	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CHHT_RS03730	COG0243	molybdopterin cofactor binding
CHHT_RS03740	COG0788	formyltetrahydrofolate deformylase activity
CHHT_RS03850	COG0745	RESPONSE REGULATOR receiver
CHHT_RS03855	COG0642	Histidine kinase
CHHT_RS03860	COG2860	membrane
CHHT_RS03865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHHT_RS03870	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHHT_RS03875	COG1580	Controls the rotational direction of flagella during chemotaxis
CHHT_RS03880	COG0736	holo-[acyl-carrier-protein] synthase activity
CHHT_RS03885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHHT_RS03900	COG1151	hydroxylamine reductase activity
CHHT_RS03920	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CHHT_RS03960	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CHHT_RS03970	COG0351	phosphomethylpyrimidine kinase
CHHT_RS03975	COG2011	ABC-type metal ion transport system permease component
CHHT_RS03980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHHT_RS04000	COG0114	fumarate hydratase activity
CHHT_RS04035	COG2048	Heterodisulfide reductase, subunit B
CHHT_RS04050	COG0326	Molecular chaperone. Has ATPase activity
CHHT_RS04060	COG3041	Addiction module toxin RelE StbE family
CHHT_RS04110	COG0582	viral genome integration into host DNA
CHHT_RS04130	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CHHT_RS04135	COG0492	ferredoxin-NADP+ reductase activity
CHHT_RS04145	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CHHT_RS04150	COG0727	PFAM Uncharacterised protein family (UPF0153)
CHHT_RS04160	COG0134	indole-3-glycerol-phosphate synthase activity
CHHT_RS04170	COG3022	response to hydroperoxide
CHHT_RS04175	COG0776	regulation of translation
CHHT_RS04185	COG2814	Major facilitator Superfamily
CHHT_RS04195	COG0439	Biotin carboxylase
CHHT_RS04215	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CHHT_RS04220	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CHHT_RS04230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHHT_RS04235	COG1674	ftsk spoiiie
CHHT_RS04235	COG1196	nuclear chromosome segregation
CHHT_RS04250	COG0142	geranyltranstransferase activity
CHHT_RS04255	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CHHT_RS04260	COG0442	prolyl-tRNA aminoacylation
CHHT_RS04270	COG0181	hydroxymethylbilane synthase activity
CHHT_RS04280	COG1696	Membrane protein involved in D-alanine export
CHHT_RS04285	COG1295	ribonuclease BN
CHHT_RS04290	COG0277	FAD linked oxidase domain protein
CHHT_RS04300	COG0739	heme binding
CHHT_RS04305	COG2239	Acts as a magnesium transporter
CHHT_RS04320	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHHT_RS04325	COG0459	protein refolding
CHHT_RS04335	COG0252	asparaginase activity
CHHT_RS04360	COG0066	3-isopropylmalate dehydratase activity
CHHT_RS04365	COG0473	3-isopropylmalate dehydrogenase activity
CHHT_RS04390	COG1610	YqeY-like protein
CHHT_RS04400	COG1459	type II secretion system
CHHT_RS04440	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CHHT_RS04445	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CHHT_RS04450	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CHHT_RS04455	COG0359	binds to the 23S rRNA
CHHT_RS04460	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHHT_RS04460	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHHT_RS04470	COG1049	propionate catabolic process, 2-methylcitrate cycle
CHHT_RS04475	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CHHT_RS04490	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CHHT_RS04495	COG0305	Participates in initiation and elongation during chromosome replication
CHHT_RS04505	COG0343	queuine tRNA-ribosyltransferase activity
CHHT_RS04525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHHT_RS04530	COG0840	transmembrane signaling receptor activity
CHHT_RS04550	COG0039	L-malate dehydrogenase activity
CHHT_RS04560	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHHT_RS04560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHHT_RS04565	COG3962	Belongs to the TPP enzyme family
CHHT_RS04575	COG0716	FMN binding
CHHT_RS04585	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CHHT_RS04590	COG0750	zinc metalloprotease
CHHT_RS04595	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHHT_RS04605	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CHHT_RS04635	COG0840	transmembrane signaling receptor activity
CHHT_RS04640	COG0556	nucleotide-excision repair
CHHT_RS04645	COG0471	metal ion transport
CHHT_RS04655	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CHHT_RS04665	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CHHT_RS04680	COG2833	Protein of unknown function (DUF455)
CHHT_RS04695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHHT_RS04700	COG0303	'Molybdopterin
CHHT_RS04715	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CHHT_RS04720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CHHT_RS04725	COG0124	histidyl-tRNA synthetase
CHHT_RS04730	COG1166	arginine decarboxylase activity
CHHT_RS04735	COG1045	serine acetyltransferase
CHHT_RS04740	COG0436	Aminotransferase
CHHT_RS04745	COG1216	Glycosyl transferase, family 2
CHHT_RS04745	COG1442	glycosyl transferase family 8
CHHT_RS04750	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHHT_RS04755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHHT_RS04760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHHT_RS04770	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CHHT_RS04775	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CHHT_RS04780	COG1137	ATPase activity
CHHT_RS04790	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CHHT_RS04795	COG0776	regulation of translation
CHHT_RS04800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHHT_RS04805	COG0772	Belongs to the SEDS family
CHHT_RS04810	COG0582	viral genome integration into host DNA
CHHT_RS04815	COG0137	argininosuccinate synthase activity
CHHT_RS04825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CHHT_RS04835	COG0375	protein maturation
CHHT_RS04840	COG0309	Hydrogenase expression formation protein (HypE)
CHHT_RS04850	COG0298	carbon dioxide binding
CHHT_RS04870	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CHHT_RS04880	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CHHT_RS04885	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CHHT_RS04890	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CHHT_RS04895	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CHHT_RS04900	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CHHT_RS04905	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CHHT_RS04915	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CHHT_RS04920	COG0745	RESPONSE REGULATOR receiver
CHHT_RS04925	COG4191	Histidine kinase
CHHT_RS04930	COG0484	heat shock protein binding
CHHT_RS04935	COG0545	Peptidyl-prolyl cis-trans isomerase
CHHT_RS04940	COG0437	4 iron, 4 sulfur cluster binding
CHHT_RS04945	COG3301	Polysulphide reductase, NrfD
CHHT_RS04950	COG1333	cytochrome c biogenesis protein
CHHT_RS04950	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHHT_RS04975	COG1136	(ABC) transporter
CHHT_RS04990	COG0542	response to heat
CHHT_RS05005	COG1131	(ABC) transporter
CHHT_RS05010	COG4771	TonB-dependent receptor
CHHT_RS05015	COG0793	Belongs to the peptidase S41A family
CHHT_RS05020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CHHT_RS05025	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHHT_RS05030	COG0047	phosphoribosylformylglycinamidine synthase activity
CHHT_RS05040	COG0204	Acyl-transferase
CHHT_RS05045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHHT_RS05105	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CHHT_RS05115	COG1338	Plays a role in the flagellum-specific transport system
CHHT_RS05120	COG0824	Thioesterase
CHHT_RS05150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHHT_RS05180	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHHT_RS05185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHHT_RS05195	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CHHT_RS05200	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CHHT_RS05210	COG0101	tRNA pseudouridine synthase activity
CHHT_RS05215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHHT_RS05225	COG3111	PFAM Bacterial OB fold (BOF) protein
CHHT_RS05230	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CHHT_RS05235	COG3421	Type III restriction
CHHT_RS05255	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CHHT_RS05265	COG0739	heme binding
CHHT_RS05275	COG3706	GGDEF domain
CHHT_RS05285	COG0495	leucyl-tRNA aminoacylation
CHHT_RS05295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHHT_RS05300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHHT_RS05305	COG1862	Preprotein translocase
CHHT_RS05310	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CHHT_RS05315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHHT_RS05320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHHT_RS05325	COG1121	(ABC) transporter
CHHT_RS05335	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CHHT_RS05340	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CHHT_RS05360	COG0210	DNA helicase
CHHT_RS05365	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CHHT_RS05380	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CHHT_RS05390	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CHHT_RS05395	COG0542	response to heat
CHHT_RS05410	COG1815	bacterial-type flagellum-dependent cell motility
CHHT_RS05430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CHHT_RS05435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CHHT_RS05460	COG0335	large ribosomal subunit rRNA binding
CHHT_RS05465	COG0336	Belongs to the RNA methyltransferase TrmD family
CHHT_RS05470	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CHHT_RS05480	COG0228	four-way junction DNA binding
CHHT_RS05485	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CHHT_RS05540	COG0310	cobalt ion transport
CHHT_RS05550	COG0564	pseudouridine synthase activity
CHHT_RS05555	COG1519	Transferase
CHHT_RS05555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CHHT_RS05565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CHHT_RS05570	COG0752	glycyl-tRNA synthetase alpha subunit
CHHT_RS05580	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CHHT_RS05595	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CHHT_RS05600	COG0174	glutamine synthetase
CHHT_RS05615	COG0753	catalase activity
CHHT_RS05635	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CHHT_RS05640	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHHT_RS05645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CHHT_RS05650	COG0612	Peptidase, M16
CHHT_RS05665	COG0579	oxidoreductase
CHHT_RS05670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHHT_RS05680	COG2199	diguanylate cyclase activity
CHHT_RS05680	COG2200	EAL domain
CHHT_RS05680	COG3287	FIST C domain
CHHT_RS05685	COG1193	negative regulation of DNA recombination
CHHT_RS05740	COG0501	Belongs to the peptidase M48B family
CHHT_RS05745	COG0733	neurotransmitter:sodium symporter activity
CHHT_RS05755	COG0477	Major facilitator Superfamily
CHHT_RS05760	COG0659	secondary active sulfate transmembrane transporter activity
CHHT_RS05765	COG0745	RESPONSE REGULATOR receiver
CHHT_RS05770	COG2205	protein histidine kinase activity
CHHT_RS05775	COG0534	Mate efflux family protein
CHHT_RS05785	COG0786	glutamate:sodium symporter activity
CHHT_RS05800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CHHT_RS05805	COG2957	Belongs to the agmatine deiminase family
CHHT_RS05815	COG1136	(ABC) transporter
CHHT_RS05815	COG0577	efflux transmembrane transporter activity
CHHT_RS05840	COG0672	)-iron permease
CHHT_RS05850	COG4786	Flagellar basal body rod
CHHT_RS05855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHHT_RS05865	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CHHT_RS05885	COG0191	fructose-bisphosphate aldolase activity
CHHT_RS05890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHHT_RS05895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CHHT_RS05900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CHHT_RS05905	COG1518	maintenance of DNA repeat elements
CHHT_RS05920	COG1203	CRISPR-associated helicase, Cas3
CHHT_RS05945	COG1596	polysaccharide export
CHHT_RS05945	COG1555	photosystem II stabilization
CHHT_RS05975	COG0586	Pfam SNARE associated Golgi protein
CHHT_RS05985	COG1418	mRNA catabolic process
CHHT_RS05995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHHT_RS06000	COG0552	protein localization to endoplasmic reticulum
CHHT_RS06005	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CHHT_RS06040	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CHHT_RS06050	COG2255	four-way junction helicase activity
CHHT_RS06055	COG0628	permease
CHHT_RS06060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CHHT_RS06065	COG1127	ABC transporter
CHHT_RS06080	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CHHT_RS06145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHHT_RS06150	COG0765	amino acid transport
CHHT_RS06155	COG1126	abc transporter atp-binding protein
CHHT_RS06170	COG0352	thiamine-phosphate diphosphorylase activity
CHHT_RS06175	COG1968	undecaprenyl-diphosphatase activity
CHHT_RS06180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CHHT_RS06190	COG0642	Histidine kinase
CHHT_RS06205	COG0587	DNA-directed DNA polymerase activity
CHHT_RS06210	COG0724	RNA recognition motif
CHHT_RS06215	COG3005	denitrification pathway
CHHT_RS06225	COG0693	protein deglycase activity
CHHT_RS06235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CHHT_RS06240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHHT_RS06250	COG0539	negative regulation of cytoplasmic translation
CHHT_RS06250	COG1185	polyribonucleotide nucleotidyltransferase activity
CHHT_RS06255	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CHHT_RS06260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CHHT_RS06270	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CHHT_RS06275	COG0537	adenosine 5'-monophosphoramidase activity
CHHT_RS06285	COG1185	polyribonucleotide nucleotidyltransferase activity
CHHT_RS06320	COG0519	Catalyzes the synthesis of GMP from XMP
CHHT_RS06360	COG2201	protein-glutamate methylesterase activity
CHHT_RS06405	COG1607	acyl-coa hydrolase
CHHT_RS06420	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHHT_RS06470	COG2207	Transcriptional regulator
CHHT_RS06475	COG1979	alcohol dehydrogenase
CHHT_RS06480	COG0733	neurotransmitter:sodium symporter activity
CHHT_RS06485	COG0511	ligase activity, forming carbon-carbon bonds
CHHT_RS06485	COG5016	pyruvate
CHHT_RS06490	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CHHT_RS06495	COG0165	Argininosuccinate lyase
CHHT_RS06500	COG0840	transmembrane signaling receptor activity
CHHT_RS06515	COG1230	cation diffusion facilitator family transporter
CHHT_RS06525	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CHHT_RS06540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHHT_RS06545	COG0049	tRNA binding
CHHT_RS06550	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CHHT_RS06555	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CHHT_RS06560	COG0085	RNA polymerase activity
CHHT_RS06565	COG0222	ribosome binding
CHHT_RS06570	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CHHT_RS06575	COG0081	regulation of translation
CHHT_RS06580	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CHHT_RS06585	COG0250	Participates in transcription elongation, termination and antitermination
CHHT_RS06600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CHHT_RS06605	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHHT_RS06635	COG0284	orotidine-5'-phosphate decarboxylase activity
CHHT_RS06640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHHT_RS06645	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CHHT_RS06650	COG2076	Multidrug Resistance protein
CHHT_RS06660	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CHHT_RS06665	COG0697	spore germination
CHHT_RS06670	COG1160	GTP binding
CHHT_RS06675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CHHT_RS06685	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CHHT_RS06695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHHT_RS06700	COG1183	phosphatidylcholine synthase activity
CHHT_RS06710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHHT_RS06715	COG2264	protein methyltransferase activity
CHHT_RS06720	COG0745	RESPONSE REGULATOR receiver
CHHT_RS06725	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CHHT_RS06730	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CHHT_RS06740	COG1086	Polysaccharide biosynthesis protein
CHHT_RS06745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CHHT_RS06755	COG2423	ornithine cyclodeaminase activity
CHHT_RS06760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHHT_RS06765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CHHT_RS06770	COG0019	diaminopimelate decarboxylase activity
CHHT_RS06795	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CHHT_RS06800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHHT_RS06825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHHT_RS06830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHHT_RS06835	COG0825	malonyl-CoA metabolic process
CHHT_RS06850	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CHHT_RS06855	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CHHT_RS06860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHHT_RS06865	COG0037	tRNA processing
CHHT_RS06885	COG2121	Domain of unknown function (DUF374)
CHHT_RS06890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHHT_RS06900	COG0195	Participates in both transcription termination and antitermination
CHHT_RS06905	COG0840	transmembrane signaling receptor activity
CHHT_RS06910	COG1739	Uncharacterized protein family UPF0029
CHHT_RS06920	COG2022	thiamine diphosphate biosynthetic process
CHHT_RS06935	COG1966	Carbon starvation protein
CHHT_RS06955	COG0488	(ABC) transporter
CHHT_RS06960	COG2171	N-acyltransferase activity
CHHT_RS06965	COG0489	protein tyrosine kinase activity
CHHT_RS06970	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CHHT_RS06975	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CHHT_RS06975	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CHHT_RS06980	COG0745	RESPONSE REGULATOR receiver
CHHT_RS06990	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CHHT_RS07000	COG1333	cytochrome c biogenesis protein
CHHT_RS07000	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHHT_RS07025	COG0683	leucine binding
CHHT_RS07030	COG2010	Cytochrome c
CHHT_RS07035	COG4773	Receptor
CHHT_RS07040	COG4773	Receptor
CHHT_RS07055	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHHT_RS07055	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHHT_RS07055	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHHT_RS07055	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHHT_RS07065	COG0668	transmembrane transport
CHHT_RS07075	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CHHT_RS07080	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CHHT_RS07085	COG1074	ATP-dependent DNA helicase activity
CHHT_RS07130	COG3278	Belongs to the heme-copper respiratory oxidase family
CHHT_RS07135	COG0745	RESPONSE REGULATOR receiver
CHHT_RS07140	COG0840	transmembrane signaling receptor activity
CHHT_RS07150	COG0505	Belongs to the CarA family
CHHT_RS07175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CHHT_RS07180	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CHHT_RS07220	COG3585	molybdate ion transport
CHHT_RS07255	COG1776	CheC inhibitor of MCP methylation
CHHT_RS07255	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHHT_RS07270	COG0133	tryptophan synthase activity
CHHT_RS07280	COG0512	Glutamine amidotransferase of anthranilate synthase
CHHT_RS07280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHHT_RS07285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CHHT_RS07290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHHT_RS07300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHHT_RS07305	COG0471	metal ion transport
CHHT_RS07310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CHHT_RS07320	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHHT_RS07325	COG0778	Nitroreductase
CHHT_RS07330	COG0709	Synthesizes selenophosphate from selenide and ATP
CHHT_RS07345	COG0193	aminoacyl-tRNA hydrolase activity
CHHT_RS07350	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CHHT_RS07360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CHHT_RS07370	COG0835	chemotaxis
CHHT_RS07375	COG2198	Histidine kinase
CHHT_RS07375	COG0784	Response regulator, receiver
CHHT_RS07375	COG0643	Histidine kinase
CHHT_RS07380	COG0835	chemotaxis
CHHT_RS07380	COG0784	Response regulator, receiver
CHHT_RS07395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHHT_RS07405	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CHHT_RS07410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CHHT_RS07430	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHHT_RS07440	COG1077	Cell shape determining protein MreB Mrl
CHHT_RS07445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CHHT_RS07450	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CHHT_RS07455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CHHT_RS07475	COG0731	radical SAM domain protein
CHHT_RS07480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHHT_RS07490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CHHT_RS07495	COG2204	response regulator
CHHT_RS07535	COG4310	Domain of unknown function (DUF2172)
CHHT_RS07555	COG1942	4-Oxalocrotonate Tautomerase
CHHT_RS07560	COG0481	GTPase activity
CHHT_RS07575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CHHT_RS07580	COG0540	Belongs to the ATCase OTCase family
CHHT_RS07590	COG2165	general secretion pathway protein
CHHT_RS07600	COG0482	sulfurtransferase activity
CHHT_RS07610	COG1611	Belongs to the LOG family
CHHT_RS07615	COG0493	'glutamate synthase
CHHT_RS07620	COG0069	glutamate synthase activity
CHHT_RS07620	COG0070	glutamate synthase
CHHT_RS07620	COG0067	glutamate synthase
CHHT_RS07625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CHHT_RS07625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CHHT_RS07635	COG0779	Required for maturation of 30S ribosomal subunits
CHHT_RS07645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHHT_RS07655	COG0083	homoserine kinase activity
CHHT_RS07665	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CHHT_RS07670	COG0384	phenazine biosynthesis protein PhzF
CHHT_RS07680	COG0287	Prephenate dehydrogenase
CHHT_RS07685	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHHT_RS07690	COG2258	MOSC domain
CHHT_RS07695	COG0616	signal peptide processing
CHHT_RS07700	COG0402	S-adenosylhomocysteine deaminase activity
CHHT_RS07705	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CHHT_RS07710	COG0006	proline dipeptidase activity
CHHT_RS07715	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CHHT_RS07720	COG1419	protein localization to endoplasmic reticulum
CHHT_RS07725	COG0455	bacterial-type flagellum organization
CHHT_RS07735	COG1191	sigma factor activity
CHHT_RS07740	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHHT_RS07745	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHHT_RS07745	COG1776	CheC inhibitor of MCP methylation
CHHT_RS07750	COG0037	tRNA processing
CHHT_RS07755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHHT_RS07760	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CHHT_RS07765	COG1047	Peptidyl-prolyl cis-trans
CHHT_RS07775	COG2885	chlorophyll binding
CHHT_RS07780	COG0823	Involved in the tonB-independent uptake of proteins
CHHT_RS07790	COG0848	biopolymer transport protein
CHHT_RS07795	COG0811	peptide transport
CHHT_RS07800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CHHT_RS07805	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CHHT_RS07810	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CHHT_RS07815	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CHHT_RS07820	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHHT_RS07830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CHHT_RS07835	COG1475	DNA binding
CHHT_RS07840	COG1192	Involved in chromosome partitioning
CHHT_RS07845	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CHHT_RS07845	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CHHT_RS07850	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHHT_RS07860	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHHT_RS07865	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CHHT_RS07870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CHHT_RS07885	COG1858	cytochrome C peroxidase
CHHT_RS07890	COG0437	4 iron, 4 sulfur cluster binding
CHHT_RS07915	COG1921	L-seryl-tRNASec selenium transferase activity
CHHT_RS07930	COG1083	cytidylyl-transferase
CHHT_RS07935	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHHT_RS07940	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHHT_RS07945	COG0529	Catalyzes the synthesis of activated sulfate
CHHT_RS07970	COG3980	spore coat polysaccharide biosynthesis protein
CHHT_RS07990	COG2089	acid synthase
CHHT_RS07995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHHT_RS08000	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CHHT_RS08005	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CHHT_RS08015	COG0281	malic enzyme
CHHT_RS08015	COG0280	phosphate acetyltransferase
CHHT_RS08020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHHT_RS08040	COG4662	Binding-protein-dependent transport system inner membrane component
CHHT_RS08050	COG0717	Belongs to the dCTP deaminase family
CHHT_RS08055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CHHT_RS08065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHHT_RS08075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHHT_RS08085	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHHT_RS08090	COG0113	porphobilinogen synthase activity
CHHT_RS08095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHHT_RS08115	COG0501	Belongs to the peptidase M48B family
CHHT_RS08120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CHHT_RS08135	COG2847	Copper chaperone PCu(A)C
CHHT_RS08140	COG1086	Polysaccharide biosynthesis protein
CHHT_RS08145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHHT_RS08150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHHT_RS08165	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CHHT_RS08170	COG1027	Aspartate ammonia-lyase
CHHT_RS08180	COG0628	permease
CHHT_RS08185	COG0730	response to heat
CHHT_RS08200	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CHHT_RS08210	COG0318	PFAM AMP-dependent synthetase and ligase
CHHT_RS08225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHHT_RS08235	COG1666	GTP binding
CHHT_RS08240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHHT_RS08245	COG0163	prenyltransferase activity
CHHT_RS08250	COG0754	glutathionylspermidine amidase activity
CHHT_RS08275	COG4771	TonB-dependent receptor
CHHT_RS08280	COG0811	peptide transport
CHHT_RS08285	COG0848	biopolymer transport protein
CHHT_RS08295	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CHHT_RS08340	COG0861	Integral membrane protein TerC family
CHHT_RS08345	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CHHT_RS08350	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CHHT_RS08350	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CHHT_RS08355	COG0606	chelatase, subunit chli
CHHT_RS08360	COG0242	peptide deformylase activity
CHHT_RS08370	COG0740	serine-type endopeptidase activity
CHHT_RS08375	COG0544	peptidyl-prolyl cis-trans isomerase activity
CHHT_RS08385	COG1157	protein secretion by the type III secretion system
CHHT_RS08425	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CHHT_RS08430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CHHT_RS08465	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CHHT_RS08470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHHT_RS08475	COG0268	Binds directly to 16S ribosomal RNA
CHHT_RS08480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CHHT_RS08500	COG0708	Exodeoxyribonuclease III
CHHT_RS08505	COG2194	sulfuric ester hydrolase activity
CHHT_RS08520	COG1971	Probably functions as a manganese efflux pump
CHHT_RS08530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHHT_RS08535	COG1121	(ABC) transporter
CHHT_RS08540	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CHHT_RS08545	COG0803	Belongs to the bacterial solute-binding protein 9 family
CHHT_RS08555	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHHT_RS08560	COG1858	cytochrome C peroxidase
CHHT_RS08565	COG5001	Diguanylate cyclase
CHHT_RS08565	COG1716	ATPase activity
CHHT_RS08570	COG0288	reversible hydration of carbon dioxide
CHHT_RS08575	COG0668	transmembrane transport
CHHT_RS08585	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CHHT_RS08590	COG0571	ribonuclease III activity
CHHT_RS08605	COG0358	DNA primase activity
CHHT_RS08645	COG0840	transmembrane signaling receptor activity
CHHT_RS08655	COG2056	Na+-H+ antiporter family
CHHT_RS08660	COG0814	amino acid
CHHT_RS08665	COG0129	dihydroxy-acid dehydratase activity
CHHT_RS08675	COG0504	CTP synthase activity
CHHT_RS08680	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CHHT_RS08685	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CHHT_RS08690	COG0748	coenzyme F420 binding
CHHT_RS08705	COG1749	Flagellar hook protein flgE
CHHT_RS08715	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CHHT_RS08720	COG0237	dephospho-CoA kinase activity
CHHT_RS08730	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CHHT_RS08735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHHT_RS08735	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CHHT_RS08740	COG0697	spore germination
CHHT_RS08755	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CHHT_RS08760	COG0233	cytoplasmic translational termination
CHHT_RS08770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHHT_RS08775	COG0670	Belongs to the BI1 family
CHHT_RS08875	COG0582	viral genome integration into host DNA
CHHT_RS08905	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHHT_RS08915	COG0300	oxidoreductase activity
CHHT_RS08935	COG0656	L-ascorbic acid biosynthetic process
CHHT_RS08940	COG0655	NAD(P)H dehydrogenase (quinone) activity
CHHT_RS08945	COG0789	Transcriptional regulator
CHHT_RS08975	COG0778	Nitroreductase
CHHT_RS08990	COG1187	pseudouridine synthase activity
CHHT_RS08995	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CHHT_RS08995	COG0517	IMP dehydrogenase activity
CHHT_RS09005	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHHT_RS09010	COG2814	Major facilitator Superfamily
CHHT_RS09015	COG0107	imidazoleglycerol-phosphate synthase activity
CHHT_RS09025	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CHHT_RS09035	COG0564	pseudouridine synthase activity
CHHT_RS09040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CHHT_RS09045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHHT_RS09050	COG0833	amino acid
CHHT_RS09055	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group