locus-tag	class	description
FFA43_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FFA43_RS00010	COG0592	DNA-directed DNA polymerase activity
FFA43_RS00015	COG0187	DNA topoisomerase II activity
FFA43_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FFA43_RS00050	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FFA43_RS00060	COG1217	gtp-binding protein TYPA
FFA43_RS00075	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FFA43_RS00100	COG0438	transferase activity, transferring glycosyl groups
FFA43_RS00105	COG3842	ATPase activity
FFA43_RS00115	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FFA43_RS00125	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FFA43_RS00135	COG0367	asparagine synthase
FFA43_RS00140	COG2089	acid synthase
FFA43_RS00150	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FFA43_RS00155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFA43_RS00155	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FFA43_RS00160	COG2030	dehydratase
FFA43_RS00175	COG0863	Belongs to the N(4) N(6)-methyltransferase family
FFA43_RS00190	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FFA43_RS00195	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FFA43_RS00200	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FFA43_RS00220	COG1083	cytidylyl-transferase
FFA43_RS00225	COG1083	cytidylyl-transferase
FFA43_RS00230	COG1083	cytidylyl-transferase
FFA43_RS00235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FFA43_RS00250	COG1028	Short-chain dehydrogenase reductase Sdr
FFA43_RS00255	COG1132	(ABC) transporter
FFA43_RS00285	COG0367	asparagine synthase
FFA43_RS00320	COG0463	Glycosyl transferase, family 2
FFA43_RS00335	COG0367	asparagine synthase
FFA43_RS00340	COG1063	alcohol dehydrogenase
FFA43_RS00355	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FFA43_RS00360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FFA43_RS00380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FFA43_RS00415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFA43_RS00430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FFA43_RS00435	COG0051	transcription antitermination factor activity, RNA binding
FFA43_RS00440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FFA43_RS00445	COG0088	Forms part of the polypeptide exit tunnel
FFA43_RS00450	COG0089	rRNA binding
FFA43_RS00455	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FFA43_RS00460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FFA43_RS00465	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FFA43_RS00470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FFA43_RS00475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FFA43_RS00485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FFA43_RS00490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FFA43_RS00495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FFA43_RS00505	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FFA43_RS00510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FFA43_RS00515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FFA43_RS00520	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FFA43_RS00525	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FFA43_RS00530	COG0200	Binds to the 23S rRNA
FFA43_RS00535	COG0201	protein transport
FFA43_RS00540	COG0024	Methionine aminopeptidase
FFA43_RS00545	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FFA43_RS00550	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FFA43_RS00555	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FFA43_RS00560	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FFA43_RS00565	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FFA43_RS00570	COG0202	RNA polymerase activity
FFA43_RS00575	COG0203	ribosomal protein L17
FFA43_RS00590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FFA43_RS00595	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FFA43_RS00605	COG0840	transmembrane signaling receptor activity
FFA43_RS00610	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FFA43_RS00625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FFA43_RS00630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FFA43_RS00635	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FFA43_RS00640	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FFA43_RS00645	COG1840	ABC-type Fe3 transport system, periplasmic component
FFA43_RS00670	COG1309	transcriptional regulator
FFA43_RS00675	COG0348	domain, Protein
FFA43_RS00680	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FFA43_RS00695	COG3260	NADH ubiquinone oxidoreductase 20
FFA43_RS00700	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFA43_RS00705	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FFA43_RS00705	COG3261	NADH dehydrogenase
FFA43_RS00710	COG0651	ATP synthesis coupled electron transport
FFA43_RS00715	COG4237	Hydrogenase 4 membrane
FFA43_RS00720	COG0650	Formate hydrogenlyase subunit 4
FFA43_RS00725	COG0651	ATP synthesis coupled electron transport
FFA43_RS00730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFA43_RS00735	COG2986	histidine ammonia-lyase
FFA43_RS00765	COG0745	RESPONSE REGULATOR receiver
FFA43_RS00800	COG0501	Belongs to the peptidase M48B family
FFA43_RS00805	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FFA43_RS00810	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FFA43_RS00815	COG1253	flavin adenine dinucleotide binding
FFA43_RS00845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FFA43_RS00850	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FFA43_RS00855	COG0475	glutathione-regulated potassium exporter activity
FFA43_RS00855	COG0569	domain protein
FFA43_RS00860	COG0372	Belongs to the citrate synthase family
FFA43_RS00870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FFA43_RS00875	COG0573	inorganic phosphate transmembrane transporter activity
FFA43_RS00885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FFA43_RS00895	COG2814	Major facilitator Superfamily
FFA43_RS00900	COG0840	transmembrane signaling receptor activity
FFA43_RS00920	COG0454	-acetyltransferase
FFA43_RS00920	COG0456	acetyltransferase
FFA43_RS00925	COG0840	transmembrane signaling receptor activity
FFA43_RS00935	COG0314	molybdopterin synthase activity
FFA43_RS00945	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FFA43_RS00950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FFA43_RS00975	COG0148	phosphopyruvate hydratase activity
FFA43_RS00980	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FFA43_RS00985	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FFA43_RS01015	COG0575	Belongs to the CDS family
FFA43_RS01020	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FFA43_RS01035	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FFA43_RS01045	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FFA43_RS01065	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FFA43_RS01070	COG0602	queuosine metabolic process
FFA43_RS01075	COG1979	alcohol dehydrogenase
FFA43_RS01090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FFA43_RS01100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFA43_RS01100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFA43_RS01105	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FFA43_RS01110	COG1360	Flagellar Motor Protein
FFA43_RS01120	COG0105	UTP biosynthetic process
FFA43_RS01130	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FFA43_RS01135	COG0416	fatty acid biosynthetic process
FFA43_RS01140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FFA43_RS01150	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FFA43_RS01160	COG0745	RESPONSE REGULATOR receiver
FFA43_RS01170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFA43_RS01185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FFA43_RS01200	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FFA43_RS01205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FFA43_RS01210	COG0450	alkyl hydroperoxide reductase
FFA43_RS01235	COG2842	Transposition protein
FFA43_RS01470	COG1570	exodeoxyribonuclease VII activity
FFA43_RS01490	COG1131	(ABC) transporter
FFA43_RS01495	COG0842	Transport permease protein
FFA43_RS01500	COG0842	Transport permease protein
FFA43_RS01510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FFA43_RS01520	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFA43_RS01525	COG1766	The M ring may be actively involved in energy transduction
FFA43_RS01530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FFA43_RS01545	COG0019	diaminopimelate decarboxylase activity
FFA43_RS01560	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FFA43_RS01565	COG4774	siderophore transport
FFA43_RS01570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFA43_RS01575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FFA43_RS01585	COG1120	ATPase activity
FFA43_RS01595	COG0811	peptide transport
FFA43_RS01600	COG0848	biopolymer transport protein
FFA43_RS01625	COG0254	rRNA binding
FFA43_RS01630	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FFA43_RS01635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FFA43_RS01650	COG0436	Aminotransferase
FFA43_RS01655	COG0460	homoserine dehydrogenase
FFA43_RS01660	COG0792	nuclease activity
FFA43_RS01665	COG3118	belongs to the thioredoxin family
FFA43_RS01670	COG0492	ferredoxin-NADP+ reductase activity
FFA43_RS01680	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FFA43_RS01685	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FFA43_RS01700	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FFA43_RS01700	COG0140	phosphoribosyl-ATP diphosphatase activity
FFA43_RS01720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FFA43_RS01730	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FFA43_RS01760	COG0723	plastoquinol--plastocyanin reductase activity
FFA43_RS01765	COG1279	arginine transmembrane transporter activity
FFA43_RS01770	COG0445	tRNA wobble uridine modification
FFA43_RS01790	COG0052	Belongs to the universal ribosomal protein uS2 family
FFA43_RS01795	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FFA43_RS01800	COG1136	(ABC) transporter
FFA43_RS01810	COG1684	flagellar biosynthetic protein fliR
FFA43_RS01825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FFA43_RS01830	COG0018	arginyl-trna synthetase
FFA43_RS01835	COG0583	DNA-binding transcription factor activity
FFA43_RS01840	COG2855	membrane
FFA43_RS01845	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FFA43_RS01855	COG0126	phosphoglycerate kinase activity
FFA43_RS01860	COG0149	triose-phosphate isomerase activity
FFA43_RS01865	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FFA43_RS01885	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FFA43_RS01890	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FFA43_RS01895	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FFA43_RS01905	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FFA43_RS01910	COG0656	L-ascorbic acid biosynthetic process
FFA43_RS01915	COG2217	Heavy metal translocating P-type atpase
FFA43_RS01945	COG0463	Glycosyl transferase, family 2
FFA43_RS01950	COG0726	polysaccharide deacetylase
FFA43_RS01965	COG0438	transferase activity, transferring glycosyl groups
FFA43_RS01970	COG0726	polysaccharide deacetylase
FFA43_RS01980	COG0438	transferase activity, transferring glycosyl groups
FFA43_RS01990	COG1560	Kdo2-lipid A biosynthetic process
FFA43_RS02000	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FFA43_RS02010	COG1793	dna ligase
FFA43_RS02020	COG2814	Major facilitator Superfamily
FFA43_RS02030	COG2244	polysaccharide biosynthetic process
FFA43_RS02035	COG0438	transferase activity, transferring glycosyl groups
FFA43_RS02045	COG0438	transferase activity, transferring glycosyl groups
FFA43_RS02055	COG0438	transferase activity, transferring glycosyl groups
FFA43_RS02060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FFA43_RS02065	COG0110	maltose O-acetyltransferase activity
FFA43_RS02075	COG0166	Belongs to the GPI family
FFA43_RS02080	COG0783	Belongs to the Dps family
FFA43_RS02095	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FFA43_RS02100	COG4106	trans-aconitate 2-methyltransferase activity
FFA43_RS02145	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FFA43_RS02170	COG3951	Flagellar rod assembly protein muramidase FlgJ
FFA43_RS02200	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FFA43_RS02205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FFA43_RS02235	COG0716	FMN binding
FFA43_RS02240	COG0814	amino acid
FFA43_RS02245	COG0217	transcriptional regulatory protein
FFA43_RS02250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FFA43_RS02255	COG1301	dicarboxylic acid transport
FFA43_RS02260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FFA43_RS02265	COG0243	molybdopterin cofactor binding
FFA43_RS02280	COG3279	Response regulator of the LytR AlgR family
FFA43_RS02285	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FFA43_RS02290	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FFA43_RS02315	COG2217	Heavy metal translocating P-type atpase
FFA43_RS02335	COG1053	succinate dehydrogenase
FFA43_RS02340	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FFA43_RS02350	COG1854	S-ribosylhomocysteine lyase activity
FFA43_RS02355	COG1007	ATP synthesis coupled electron transport
FFA43_RS02360	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFA43_RS02365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FFA43_RS02370	COG0713	ATP synthesis coupled electron transport
FFA43_RS02375	COG0839	Belongs to the complex I subunit 6 family
FFA43_RS02380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFA43_RS02385	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FFA43_RS02390	COG1034	ATP synthesis coupled electron transport
FFA43_RS02395	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FFA43_RS02405	COG0649	NAD binding
FFA43_RS02410	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFA43_RS02415	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFA43_RS02420	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FFA43_RS02435	COG4263	nitrous-oxide reductase activity
FFA43_RS02450	COG0437	4 iron, 4 sulfur cluster binding
FFA43_RS02465	COG0348	domain, Protein
FFA43_RS02470	COG3842	ATPase activity
FFA43_RS02490	COG0824	Thioesterase
FFA43_RS02510	COG0004	ammonium transporteR
FFA43_RS02515	COG0347	Belongs to the P(II) protein family
FFA43_RS02520	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FFA43_RS02525	COG0594	ribonuclease P activity
FFA43_RS02535	COG0706	membrane insertase activity
FFA43_RS02545	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FFA43_RS02550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FFA43_RS02555	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FFA43_RS02560	COG0138	bifunctional purine biosynthesis protein purh
FFA43_RS02575	COG2151	metal-sulfur cluster biosynthetic enzyme
FFA43_RS02580	COG0840	transmembrane signaling receptor activity
FFA43_RS02605	COG0275	rRNA processing
FFA43_RS02620	COG0849	cell division
FFA43_RS02625	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FFA43_RS02635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FFA43_RS02645	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FFA43_RS02650	COG0653	protein targeting
FFA43_RS02655	COG4591	ABC-type transport system involved in lipoprotein release permease component
FFA43_RS02680	COG2252	PERMEase
FFA43_RS02685	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FFA43_RS02690	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FFA43_RS02695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FFA43_RS02710	COG0745	RESPONSE REGULATOR receiver
FFA43_RS02715	COG3301	Polysulphide reductase, NrfD
FFA43_RS02720	COG0437	4 iron, 4 sulfur cluster binding
FFA43_RS02725	COG0243	molybdopterin cofactor binding
FFA43_RS02735	COG0425	Belongs to the sulfur carrier protein TusA family
FFA43_RS02740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FFA43_RS02745	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FFA43_RS02770	COG1555	photosystem II stabilization
FFA43_RS02770	COG1596	polysaccharide export
FFA43_RS02825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FFA43_RS02835	COG1058	Belongs to the CinA family
FFA43_RS02835	COG1546	Belongs to the CinA family
FFA43_RS02845	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FFA43_RS02850	COG0154	amidase activity
FFA43_RS02855	COG0516	GMP reductase activity
FFA43_RS02855	COG0517	IMP dehydrogenase activity
FFA43_RS02860	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FFA43_RS02875	COG1999	signal sequence binding
FFA43_RS02880	COG0772	Belongs to the SEDS family
FFA43_RS02885	COG0564	pseudouridine synthase activity
FFA43_RS02895	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FFA43_RS02900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FFA43_RS02915	COG0528	UMP kinase activity
FFA43_RS02920	COG1758	RNA polymerase activity
FFA43_RS02930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FFA43_RS02940	COG0860	N-Acetylmuramoyl-L-alanine amidase
FFA43_RS02945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFA43_RS02945	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FFA43_RS02955	COG0519	Catalyzes the synthesis of GMP from XMP
FFA43_RS02960	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FFA43_RS02965	COG0563	adenylate kinase activity
FFA43_RS02970	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FFA43_RS02980	COG0497	DNA recombination
FFA43_RS02990	COG0084	hydrolase, TatD family'
FFA43_RS03000	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FFA43_RS03005	COG0131	Imidazoleglycerol-phosphate dehydratase
FFA43_RS03025	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FFA43_RS03040	COG0768	penicillin binding
FFA43_RS03045	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFA43_RS03070	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FFA43_RS03080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FFA43_RS03085	COG0681	Belongs to the peptidase S26 family
FFA43_RS03095	COG0698	ribose 5-phosphate isomerase
FFA43_RS03105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FFA43_RS03115	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FFA43_RS03120	COG0012	GTP binding
FFA43_RS03125	COG0243	molybdopterin cofactor binding
FFA43_RS03130	COG0437	4 iron, 4 sulfur cluster binding
FFA43_RS03135	COG0348	domain, Protein
FFA43_RS03140	COG3043	anaerobic respiration
FFA43_RS03160	COG0688	phosphatidylethanolamine metabolic process
FFA43_RS03165	COG1408	metallophosphoesterase
FFA43_RS03170	COG1114	Component of the transport system for branched-chain amino acids
FFA43_RS03175	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FFA43_RS03200	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FFA43_RS03220	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FFA43_RS03225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FFA43_RS03240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FFA43_RS03250	COG0642	Histidine kinase
FFA43_RS03255	COG0745	RESPONSE REGULATOR receiver
FFA43_RS03260	COG0484	heat shock protein binding
FFA43_RS03265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FFA43_RS03270	COG0629	single-stranded DNA binding
FFA43_RS03275	COG0360	Binds together with S18 to 16S ribosomal RNA
FFA43_RS03285	COG0557	exoribonuclease II activity
FFA43_RS03295	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FFA43_RS03300	COG2861	carbohydrate metabolic process
FFA43_RS03305	COG0758	DNA mediated transformation
FFA43_RS03310	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FFA43_RS03325	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FFA43_RS03330	COG0805	protein transport
FFA43_RS03335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FFA43_RS03340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FFA43_RS03345	COG0494	nUDIX hydrolase
FFA43_RS03350	COG0527	aspartate kinase activity
FFA43_RS03365	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FFA43_RS03370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FFA43_RS03375	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FFA43_RS03380	COG0196	riboflavin kinase activity
FFA43_RS03385	COG2226	methyltransferase
FFA43_RS03400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FFA43_RS03405	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FFA43_RS03410	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FFA43_RS03415	COG1959	2 iron, 2 sulfur cluster binding
FFA43_RS03420	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFA43_RS03440	COG1420	regulation of RNA biosynthetic process
FFA43_RS03445	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FFA43_RS03450	COG0443	Heat shock 70 kDa protein
FFA43_RS03470	COG3706	GGDEF domain
FFA43_RS03475	COG2203	Gaf domain
FFA43_RS03475	COG2199	diguanylate cyclase activity
FFA43_RS03485	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FFA43_RS03490	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FFA43_RS03495	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FFA43_RS03500	COG1663	tetraacyldisaccharide 4'-kinase activity
FFA43_RS03510	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FFA43_RS03525	COG0500	methyltransferase
FFA43_RS03530	COG2195	Cleaves the N-terminal amino acid of tripeptides
FFA43_RS03555	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FFA43_RS03560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFA43_RS03565	COG0577	efflux transmembrane transporter activity
FFA43_RS03565	COG1136	(ABC) transporter
FFA43_RS03570	COG1538	Outer membrane efflux protein
FFA43_RS03580	COG0642	Histidine kinase
FFA43_RS03585	COG0745	RESPONSE REGULATOR receiver
FFA43_RS03595	COG0484	heat shock protein binding
FFA43_RS03600	COG0789	Transcriptional regulator
FFA43_RS03610	COG3263	regulation of cellular component size
FFA43_RS03615	COG0730	response to heat
FFA43_RS03620	COG0356	it plays a direct role in the translocation of protons across the membrane
FFA43_RS03630	COG0352	thiamine-phosphate diphosphorylase activity
FFA43_RS03635	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FFA43_RS03640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FFA43_RS03655	COG2962	Rard protein
FFA43_RS03660	COG1126	abc transporter atp-binding protein
FFA43_RS03665	COG0765	amino acid transport
FFA43_RS03670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFA43_RS03675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FFA43_RS03680	COG1028	Short-chain dehydrogenase reductase Sdr
FFA43_RS03685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFA43_RS03690	COG0612	Peptidase, M16
FFA43_RS03695	COG0167	dihydroorotate dehydrogenase activity
FFA43_RS03700	COG1132	(ABC) transporter
FFA43_RS03705	COG0215	cysteine-tRNA ligase activity
FFA43_RS03710	COG0728	peptidoglycan biosynthetic process
FFA43_RS03715	COG0513	Belongs to the DEAD box helicase family
FFA43_RS03730	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FFA43_RS03740	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFA43_RS03740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFA43_RS03790	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FFA43_RS03800	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FFA43_RS03805	COG2201	protein-glutamate methylesterase activity
FFA43_RS03815	COG0632	four-way junction helicase activity
FFA43_RS03820	COG1181	Belongs to the D-alanine--D-alanine ligase family
FFA43_RS03835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FFA43_RS03845	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FFA43_RS03850	COG0280	phosphate acetyltransferase
FFA43_RS03855	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FFA43_RS03860	COG0028	Belongs to the TPP enzyme family
FFA43_RS03865	COG0440	acetolactate synthase activity
FFA43_RS03875	COG0586	Pfam SNARE associated Golgi protein
FFA43_RS03885	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FFA43_RS03900	COG0745	RESPONSE REGULATOR receiver
FFA43_RS03910	COG0243	molybdopterin cofactor binding
FFA43_RS03920	COG0788	formyltetrahydrofolate deformylase activity
FFA43_RS03945	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FFA43_RS03950	COG0471	metal ion transport
FFA43_RS04015	COG0745	RESPONSE REGULATOR receiver
FFA43_RS04020	COG0642	Histidine kinase
FFA43_RS04025	COG2860	membrane
FFA43_RS04030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FFA43_RS04035	COG0179	Fumarylacetoacetate (FAA) hydrolase
FFA43_RS04040	COG1580	Controls the rotational direction of flagella during chemotaxis
FFA43_RS04045	COG0736	holo-[acyl-carrier-protein] synthase activity
FFA43_RS04050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FFA43_RS04065	COG1151	hydroxylamine reductase activity
FFA43_RS04085	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FFA43_RS04120	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FFA43_RS04130	COG0351	phosphomethylpyrimidine kinase
FFA43_RS04135	COG2011	ABC-type metal ion transport system permease component
FFA43_RS04140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FFA43_RS04155	COG0114	fumarate hydratase activity
FFA43_RS04190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FFA43_RS04200	COG0326	Molecular chaperone. Has ATPase activity
FFA43_RS04220	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FFA43_RS04225	COG0492	ferredoxin-NADP+ reductase activity
FFA43_RS04235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FFA43_RS04240	COG0727	PFAM Uncharacterised protein family (UPF0153)
FFA43_RS04250	COG0134	indole-3-glycerol-phosphate synthase activity
FFA43_RS04260	COG3022	response to hydroperoxide
FFA43_RS04265	COG0776	regulation of translation
FFA43_RS04275	COG2814	Major facilitator Superfamily
FFA43_RS04285	COG0439	Biotin carboxylase
FFA43_RS04305	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FFA43_RS04310	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FFA43_RS04320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFA43_RS04325	COG1196	nuclear chromosome segregation
FFA43_RS04325	COG1674	ftsk spoiiie
FFA43_RS04340	COG0142	geranyltranstransferase activity
FFA43_RS04345	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FFA43_RS04350	COG0442	prolyl-tRNA aminoacylation
FFA43_RS04360	COG0181	hydroxymethylbilane synthase activity
FFA43_RS04370	COG1696	Membrane protein involved in D-alanine export
FFA43_RS04375	COG1295	ribonuclease BN
FFA43_RS04380	COG0277	FAD linked oxidase domain protein
FFA43_RS04390	COG0739	heme binding
FFA43_RS04395	COG2239	Acts as a magnesium transporter
FFA43_RS04410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FFA43_RS04415	COG0459	protein refolding
FFA43_RS04430	COG0252	asparaginase activity
FFA43_RS04450	COG0066	3-isopropylmalate dehydratase activity
FFA43_RS04455	COG0473	3-isopropylmalate dehydrogenase activity
FFA43_RS04475	COG0248	Ppx GppA phosphatase
FFA43_RS04480	COG1610	YqeY-like protein
FFA43_RS04490	COG1459	type II secretion system
FFA43_RS04495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FFA43_RS04530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FFA43_RS04535	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FFA43_RS04540	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FFA43_RS04545	COG0359	binds to the 23S rRNA
FFA43_RS04550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FFA43_RS04550	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FFA43_RS04560	COG1049	propionate catabolic process, 2-methylcitrate cycle
FFA43_RS04565	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FFA43_RS04585	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FFA43_RS04590	COG0305	Participates in initiation and elongation during chromosome replication
FFA43_RS04600	COG0343	queuine tRNA-ribosyltransferase activity
FFA43_RS04620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FFA43_RS04625	COG0840	transmembrane signaling receptor activity
FFA43_RS04645	COG0039	L-malate dehydrogenase activity
FFA43_RS04655	COG0674	pyruvate-flavodoxin oxidoreductase activity
FFA43_RS04655	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FFA43_RS04660	COG3962	Belongs to the TPP enzyme family
FFA43_RS04680	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FFA43_RS04685	COG0750	zinc metalloprotease
FFA43_RS04690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FFA43_RS04700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FFA43_RS04730	COG0840	transmembrane signaling receptor activity
FFA43_RS04735	COG0556	nucleotide-excision repair
FFA43_RS04750	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FFA43_RS04755	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FFA43_RS04770	COG2833	Protein of unknown function (DUF455)
FFA43_RS04785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FFA43_RS04790	COG0303	'Molybdopterin
FFA43_RS04805	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FFA43_RS04810	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FFA43_RS04815	COG0124	histidyl-tRNA synthetase
FFA43_RS04820	COG1166	arginine decarboxylase activity
FFA43_RS04825	COG1045	serine acetyltransferase
FFA43_RS04830	COG0436	Aminotransferase
FFA43_RS04835	COG1442	glycosyl transferase family 8
FFA43_RS04835	COG1216	Glycosyl transferase, family 2
FFA43_RS04840	COG0521	Mo-molybdopterin cofactor biosynthetic process
FFA43_RS04845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FFA43_RS04850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FFA43_RS04860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FFA43_RS04865	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FFA43_RS04870	COG1137	ATPase activity
FFA43_RS04880	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FFA43_RS04885	COG0776	regulation of translation
FFA43_RS04890	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FFA43_RS04895	COG0772	Belongs to the SEDS family
FFA43_RS04900	COG0582	viral genome integration into host DNA
FFA43_RS04905	COG0137	argininosuccinate synthase activity
FFA43_RS04915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FFA43_RS04930	COG0309	Hydrogenase expression formation protein (HypE)
FFA43_RS04935	COG0409	Hydrogenase expression formation protein
FFA43_RS04940	COG0298	carbon dioxide binding
FFA43_RS04945	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FFA43_RS04955	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FFA43_RS04960	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FFA43_RS04965	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FFA43_RS04970	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
FFA43_RS04975	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FFA43_RS04980	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FFA43_RS04990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FFA43_RS04995	COG0745	RESPONSE REGULATOR receiver
FFA43_RS05000	COG4191	Histidine kinase
FFA43_RS05005	COG0484	heat shock protein binding
FFA43_RS05010	COG0545	Peptidyl-prolyl cis-trans isomerase
FFA43_RS05015	COG0437	4 iron, 4 sulfur cluster binding
FFA43_RS05020	COG3301	Polysulphide reductase, NrfD
FFA43_RS05050	COG1136	(ABC) transporter
FFA43_RS05065	COG0542	response to heat
FFA43_RS05080	COG1131	(ABC) transporter
FFA43_RS05090	COG4771	TonB-dependent receptor
FFA43_RS05100	COG0793	Belongs to the peptidase S41A family
FFA43_RS05105	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FFA43_RS05110	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FFA43_RS05115	COG0047	phosphoribosylformylglycinamidine synthase activity
FFA43_RS05125	COG0204	Acyl-transferase
FFA43_RS05130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FFA43_RS05170	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FFA43_RS05180	COG1338	Plays a role in the flagellum-specific transport system
FFA43_RS05185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFA43_RS05190	COG1028	Short-chain dehydrogenase reductase Sdr
FFA43_RS05200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFA43_RS05230	COG0824	Thioesterase
FFA43_RS05250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FFA43_RS05275	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FFA43_RS05280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FFA43_RS05290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FFA43_RS05295	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FFA43_RS05305	COG0101	tRNA pseudouridine synthase activity
FFA43_RS05310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FFA43_RS05320	COG3111	PFAM Bacterial OB fold (BOF) protein
FFA43_RS05340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FFA43_RS05350	COG0739	heme binding
FFA43_RS05370	COG0495	leucyl-tRNA aminoacylation
FFA43_RS05380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FFA43_RS05385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FFA43_RS05390	COG1862	Preprotein translocase
FFA43_RS05395	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FFA43_RS05400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFA43_RS05405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFA43_RS05410	COG1121	(ABC) transporter
FFA43_RS05420	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FFA43_RS05425	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FFA43_RS05445	COG0210	DNA helicase
FFA43_RS05465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FFA43_RS05475	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FFA43_RS05480	COG0542	response to heat
FFA43_RS05495	COG1815	bacterial-type flagellum-dependent cell motility
FFA43_RS05515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FFA43_RS05520	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FFA43_RS05545	COG0335	large ribosomal subunit rRNA binding
FFA43_RS05550	COG0336	Belongs to the RNA methyltransferase TrmD family
FFA43_RS05555	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FFA43_RS05565	COG0228	four-way junction DNA binding
FFA43_RS05570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FFA43_RS05575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FFA43_RS05600	COG0310	cobalt ion transport
FFA43_RS05610	COG0564	pseudouridine synthase activity
FFA43_RS05615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FFA43_RS05615	COG1519	Transferase
FFA43_RS05625	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FFA43_RS05630	COG0752	glycyl-tRNA synthetase alpha subunit
FFA43_RS05640	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FFA43_RS05645	COG0826	peptidase U32
FFA43_RS05655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FFA43_RS05660	COG0174	glutamine synthetase
FFA43_RS05675	COG0753	catalase activity
FFA43_RS05685	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FFA43_RS05690	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FFA43_RS05695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FFA43_RS05700	COG0612	Peptidase, M16
FFA43_RS05715	COG0579	oxidoreductase
FFA43_RS05720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FFA43_RS05730	COG2199	diguanylate cyclase activity
FFA43_RS05730	COG2200	EAL domain
FFA43_RS05730	COG3287	FIST C domain
FFA43_RS05735	COG1193	negative regulation of DNA recombination
FFA43_RS05755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFA43_RS05785	COG2890	protein-(glutamine-N5) methyltransferase activity
FFA43_RS05790	COG0501	Belongs to the peptidase M48B family
FFA43_RS05795	COG0733	neurotransmitter:sodium symporter activity
FFA43_RS05800	COG0488	(ABC) transporter
FFA43_RS05810	COG0659	secondary active sulfate transmembrane transporter activity
FFA43_RS05815	COG0745	RESPONSE REGULATOR receiver
FFA43_RS05820	COG2205	protein histidine kinase activity
FFA43_RS05825	COG0534	Mate efflux family protein
FFA43_RS05835	COG0786	glutamate:sodium symporter activity
FFA43_RS05850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FFA43_RS05855	COG2957	Belongs to the agmatine deiminase family
FFA43_RS05865	COG1136	(ABC) transporter
FFA43_RS05865	COG0577	efflux transmembrane transporter activity
FFA43_RS05890	COG0672	)-iron permease
FFA43_RS05900	COG4786	Flagellar basal body rod
FFA43_RS05905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FFA43_RS05915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FFA43_RS05935	COG0191	fructose-bisphosphate aldolase activity
FFA43_RS05940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FFA43_RS05945	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FFA43_RS05950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FFA43_RS05955	COG1518	maintenance of DNA repeat elements
FFA43_RS05970	COG1203	CRISPR-associated helicase, Cas3
FFA43_RS05995	COG1596	polysaccharide export
FFA43_RS05995	COG1555	photosystem II stabilization
FFA43_RS06025	COG0586	Pfam SNARE associated Golgi protein
FFA43_RS06035	COG1418	mRNA catabolic process
FFA43_RS06045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFA43_RS06050	COG0552	protein localization to endoplasmic reticulum
FFA43_RS06055	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FFA43_RS06120	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FFA43_RS06130	COG2255	four-way junction helicase activity
FFA43_RS06135	COG0628	permease
FFA43_RS06140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FFA43_RS06145	COG1127	ABC transporter
FFA43_RS06160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FFA43_RS06175	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FFA43_RS06190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FFA43_RS06195	COG0765	amino acid transport
FFA43_RS06200	COG1126	abc transporter atp-binding protein
FFA43_RS06215	COG0352	thiamine-phosphate diphosphorylase activity
FFA43_RS06220	COG1968	undecaprenyl-diphosphatase activity
FFA43_RS06235	COG0642	Histidine kinase
FFA43_RS06245	COG0587	DNA-directed DNA polymerase activity
FFA43_RS06250	COG0724	RNA recognition motif
FFA43_RS06255	COG3005	denitrification pathway
FFA43_RS06260	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FFA43_RS06265	COG0693	protein deglycase activity
FFA43_RS06280	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FFA43_RS06285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FFA43_RS06295	COG1185	polyribonucleotide nucleotidyltransferase activity
FFA43_RS06295	COG0539	negative regulation of cytoplasmic translation
FFA43_RS06300	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FFA43_RS06305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FFA43_RS06315	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FFA43_RS06320	COG0537	adenosine 5'-monophosphoramidase activity
FFA43_RS06330	COG1185	polyribonucleotide nucleotidyltransferase activity
FFA43_RS06365	COG0519	Catalyzes the synthesis of GMP from XMP
FFA43_RS06390	COG2201	protein-glutamate methylesterase activity
FFA43_RS06440	COG1607	acyl-coa hydrolase
FFA43_RS06455	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FFA43_RS06505	COG1979	alcohol dehydrogenase
FFA43_RS06510	COG0733	neurotransmitter:sodium symporter activity
FFA43_RS06515	COG0511	ligase activity, forming carbon-carbon bonds
FFA43_RS06515	COG5016	pyruvate
FFA43_RS06520	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FFA43_RS06525	COG0165	Argininosuccinate lyase
FFA43_RS06530	COG5278	phosphoserine phosphatase activity
FFA43_RS06530	COG0840	transmembrane signaling receptor activity
FFA43_RS06540	COG1230	cation diffusion facilitator family transporter
FFA43_RS06550	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FFA43_RS06565	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FFA43_RS06570	COG0049	tRNA binding
FFA43_RS06575	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FFA43_RS06580	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FFA43_RS06585	COG0085	RNA polymerase activity
FFA43_RS06590	COG0222	ribosome binding
FFA43_RS06595	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FFA43_RS06600	COG0081	regulation of translation
FFA43_RS06605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FFA43_RS06610	COG0250	Participates in transcription elongation, termination and antitermination
FFA43_RS06625	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FFA43_RS06630	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FFA43_RS06660	COG0284	orotidine-5'-phosphate decarboxylase activity
FFA43_RS06665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FFA43_RS06670	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FFA43_RS06675	COG2076	Multidrug Resistance protein
FFA43_RS06685	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FFA43_RS06690	COG0697	spore germination
FFA43_RS06695	COG1160	GTP binding
FFA43_RS06700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FFA43_RS06710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FFA43_RS06720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FFA43_RS06725	COG1183	phosphatidylcholine synthase activity
FFA43_RS06735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FFA43_RS06740	COG2264	protein methyltransferase activity
FFA43_RS06745	COG0745	RESPONSE REGULATOR receiver
FFA43_RS06750	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FFA43_RS06755	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FFA43_RS06765	COG1086	Polysaccharide biosynthesis protein
FFA43_RS06770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FFA43_RS06795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFA43_RS06800	COG0019	diaminopimelate decarboxylase activity
FFA43_RS06810	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FFA43_RS06820	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FFA43_RS06825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FFA43_RS06850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FFA43_RS06855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFA43_RS06860	COG0825	malonyl-CoA metabolic process
FFA43_RS06875	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FFA43_RS06880	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FFA43_RS06885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FFA43_RS06890	COG0037	tRNA processing
FFA43_RS06910	COG2121	Domain of unknown function (DUF374)
FFA43_RS06915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FFA43_RS06925	COG0195	Participates in both transcription termination and antitermination
FFA43_RS06930	COG0840	transmembrane signaling receptor activity
FFA43_RS06935	COG1739	Uncharacterized protein family UPF0029
FFA43_RS06945	COG2022	thiamine diphosphate biosynthetic process
FFA43_RS06955	COG0471	metal ion transport
FFA43_RS06965	COG1053	succinate dehydrogenase
FFA43_RS06965	COG3976	FMN-binding domain protein
FFA43_RS06995	COG1966	Carbon starvation protein
FFA43_RS07010	COG0488	(ABC) transporter
FFA43_RS07015	COG2171	N-acyltransferase activity
FFA43_RS07020	COG0489	protein tyrosine kinase activity
FFA43_RS07025	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FFA43_RS07030	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FFA43_RS07030	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FFA43_RS07035	COG0745	RESPONSE REGULATOR receiver
FFA43_RS07045	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FFA43_RS07055	COG1333	cytochrome c biogenesis protein
FFA43_RS07055	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FFA43_RS07075	COG0559	Belongs to the binding-protein-dependent transport system permease family
FFA43_RS07080	COG0683	leucine binding
FFA43_RS07085	COG2010	Cytochrome c
FFA43_RS07090	COG4773	Receptor
FFA43_RS07095	COG4773	Receptor
FFA43_RS07110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFA43_RS07110	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FFA43_RS07110	COG1013	pyruvate-flavodoxin oxidoreductase activity
FFA43_RS07110	COG0674	pyruvate-flavodoxin oxidoreductase activity
FFA43_RS07120	COG0668	transmembrane transport
FFA43_RS07130	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FFA43_RS07135	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FFA43_RS07140	COG1074	ATP-dependent DNA helicase activity
FFA43_RS07180	COG3278	Belongs to the heme-copper respiratory oxidase family
FFA43_RS07185	COG0745	RESPONSE REGULATOR receiver
FFA43_RS07190	COG0840	transmembrane signaling receptor activity
FFA43_RS07200	COG0505	Belongs to the CarA family
FFA43_RS07225	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FFA43_RS07230	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FFA43_RS07265	COG3585	molybdate ion transport
FFA43_RS07300	COG1776	CheC inhibitor of MCP methylation
FFA43_RS07300	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFA43_RS07315	COG0133	tryptophan synthase activity
FFA43_RS07325	COG0512	Glutamine amidotransferase of anthranilate synthase
FFA43_RS07325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FFA43_RS07330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FFA43_RS07340	COG0471	metal ion transport
FFA43_RS07345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FFA43_RS07350	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FFA43_RS07355	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFA43_RS07360	COG0778	Nitroreductase
FFA43_RS07365	COG0709	Synthesizes selenophosphate from selenide and ATP
FFA43_RS07380	COG0193	aminoacyl-tRNA hydrolase activity
FFA43_RS07385	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FFA43_RS07395	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FFA43_RS07405	COG0835	chemotaxis
FFA43_RS07410	COG2198	Histidine kinase
FFA43_RS07410	COG0784	Response regulator, receiver
FFA43_RS07410	COG0643	Histidine kinase
FFA43_RS07415	COG0784	Response regulator, receiver
FFA43_RS07415	COG0835	chemotaxis
FFA43_RS07430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FFA43_RS07440	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FFA43_RS07445	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FFA43_RS07465	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FFA43_RS07475	COG1077	Cell shape determining protein MreB Mrl
FFA43_RS07480	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FFA43_RS07485	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FFA43_RS07490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FFA43_RS07515	COG0731	radical SAM domain protein
FFA43_RS07520	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FFA43_RS07530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FFA43_RS07535	COG2204	response regulator
FFA43_RS07555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FFA43_RS07600	COG1942	4-Oxalocrotonate Tautomerase
FFA43_RS07605	COG0481	GTPase activity
FFA43_RS07610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FFA43_RS07615	COG0540	Belongs to the ATCase OTCase family
FFA43_RS07635	COG0482	sulfurtransferase activity
FFA43_RS07645	COG1611	Belongs to the LOG family
FFA43_RS07650	COG0493	'glutamate synthase
FFA43_RS07655	COG0070	glutamate synthase
FFA43_RS07655	COG0069	glutamate synthase activity
FFA43_RS07655	COG0067	glutamate synthase
FFA43_RS07660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FFA43_RS07660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FFA43_RS07670	COG0779	Required for maturation of 30S ribosomal subunits
FFA43_RS07680	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FFA43_RS07690	COG0083	homoserine kinase activity
FFA43_RS07700	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FFA43_RS07705	COG0384	phenazine biosynthesis protein PhzF
FFA43_RS07715	COG0287	Prephenate dehydrogenase
FFA43_RS07720	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FFA43_RS07725	COG2258	MOSC domain
FFA43_RS07730	COG0616	signal peptide processing
FFA43_RS07735	COG0402	S-adenosylhomocysteine deaminase activity
FFA43_RS07740	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FFA43_RS07745	COG0006	proline dipeptidase activity
FFA43_RS07750	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FFA43_RS07755	COG1419	protein localization to endoplasmic reticulum
FFA43_RS07760	COG0455	bacterial-type flagellum organization
FFA43_RS07770	COG1191	sigma factor activity
FFA43_RS07775	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFA43_RS07780	COG1776	CheC inhibitor of MCP methylation
FFA43_RS07780	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFA43_RS07785	COG0037	tRNA processing
FFA43_RS07790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FFA43_RS07795	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FFA43_RS07800	COG1047	Peptidyl-prolyl cis-trans
FFA43_RS07810	COG2885	chlorophyll binding
FFA43_RS07825	COG0848	biopolymer transport protein
FFA43_RS07830	COG0811	peptide transport
FFA43_RS07835	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FFA43_RS07840	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FFA43_RS07845	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FFA43_RS07850	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FFA43_RS07855	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FFA43_RS07865	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FFA43_RS07870	COG1475	DNA binding
FFA43_RS07875	COG1192	Involved in chromosome partitioning
FFA43_RS07880	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FFA43_RS07880	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FFA43_RS07885	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FFA43_RS07895	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FFA43_RS07900	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FFA43_RS07905	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FFA43_RS07920	COG1858	cytochrome C peroxidase
FFA43_RS07925	COG0437	4 iron, 4 sulfur cluster binding
FFA43_RS07950	COG1921	L-seryl-tRNASec selenium transferase activity
FFA43_RS07965	COG1083	cytidylyl-transferase
FFA43_RS07995	COG2089	acid synthase
FFA43_RS08000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FFA43_RS08005	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FFA43_RS08010	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FFA43_RS08020	COG0280	phosphate acetyltransferase
FFA43_RS08020	COG0281	malic enzyme
FFA43_RS08025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FFA43_RS08045	COG4662	Binding-protein-dependent transport system inner membrane component
FFA43_RS08055	COG0717	Belongs to the dCTP deaminase family
FFA43_RS08060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FFA43_RS08075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FFA43_RS08085	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FFA43_RS08090	COG0113	porphobilinogen synthase activity
FFA43_RS08095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FFA43_RS08100	COG0357	Ribosomal RNA small subunit methyltransferase G
FFA43_RS08115	COG0501	Belongs to the peptidase M48B family
FFA43_RS08120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FFA43_RS08135	COG2847	Copper chaperone PCu(A)C
FFA43_RS08140	COG1086	Polysaccharide biosynthesis protein
FFA43_RS08145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFA43_RS08150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFA43_RS08160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFA43_RS08165	COG4797	methyltransferase
FFA43_RS08165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FFA43_RS08180	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FFA43_RS08185	COG1027	Aspartate ammonia-lyase
FFA43_RS08195	COG0628	permease
FFA43_RS08200	COG0730	response to heat
FFA43_RS08215	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FFA43_RS08225	COG0318	PFAM AMP-dependent synthetase and ligase
FFA43_RS08240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FFA43_RS08250	COG1666	GTP binding
FFA43_RS08255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFA43_RS08260	COG0163	prenyltransferase activity
FFA43_RS08265	COG0754	glutathionylspermidine amidase activity
FFA43_RS08290	COG4771	TonB-dependent receptor
FFA43_RS08295	COG0811	peptide transport
FFA43_RS08300	COG0848	biopolymer transport protein
FFA43_RS08365	COG0861	Integral membrane protein TerC family
FFA43_RS08370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FFA43_RS08375	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FFA43_RS08375	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FFA43_RS08380	COG0606	chelatase, subunit chli
FFA43_RS08385	COG0242	peptide deformylase activity
FFA43_RS08395	COG0740	serine-type endopeptidase activity
FFA43_RS08400	COG0544	peptidyl-prolyl cis-trans isomerase activity
FFA43_RS08410	COG1157	protein secretion by the type III secretion system
FFA43_RS08430	COG2703	oxygen carrier activity
FFA43_RS08435	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FFA43_RS08440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FFA43_RS08460	COG1981	membrane
FFA43_RS08470	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FFA43_RS08475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FFA43_RS08480	COG0268	Binds directly to 16S ribosomal RNA
FFA43_RS08485	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FFA43_RS08495	COG2315	Protein conserved in bacteria
FFA43_RS08505	COG0708	Exodeoxyribonuclease III
FFA43_RS08510	COG2194	sulfuric ester hydrolase activity
FFA43_RS08525	COG1971	Probably functions as a manganese efflux pump
FFA43_RS08535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFA43_RS08540	COG1121	(ABC) transporter
FFA43_RS08550	COG0803	Belongs to the bacterial solute-binding protein 9 family
FFA43_RS08560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FFA43_RS08565	COG1858	cytochrome C peroxidase
FFA43_RS08570	COG5001	Diguanylate cyclase
FFA43_RS08570	COG3300	MHYT domain
FFA43_RS08575	COG0288	reversible hydration of carbon dioxide
FFA43_RS08580	COG0668	transmembrane transport
FFA43_RS08585	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FFA43_RS08590	COG0571	ribonuclease III activity
FFA43_RS08605	COG0358	DNA primase activity
FFA43_RS08645	COG2056	Na+-H+ antiporter family
FFA43_RS08650	COG0814	amino acid
FFA43_RS08655	COG0129	dihydroxy-acid dehydratase activity
FFA43_RS08665	COG0504	CTP synthase activity
FFA43_RS08670	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FFA43_RS08675	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FFA43_RS08680	COG0748	coenzyme F420 binding
FFA43_RS08695	COG1749	Flagellar hook protein flgE
FFA43_RS08705	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FFA43_RS08710	COG0237	dephospho-CoA kinase activity
FFA43_RS08720	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FFA43_RS08725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FFA43_RS08725	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FFA43_RS08730	COG0697	spore germination
FFA43_RS08735	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FFA43_RS08745	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FFA43_RS08750	COG0233	cytoplasmic translational termination
FFA43_RS08760	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FFA43_RS08765	COG0670	Belongs to the BI1 family
FFA43_RS08770	COG2249	NAD(P)H dehydrogenase (quinone) activity
FFA43_RS08825	COG0582	viral genome integration into host DNA
FFA43_RS08855	COG2249	NAD(P)H dehydrogenase (quinone) activity
FFA43_RS08865	COG0300	oxidoreductase activity
FFA43_RS08890	COG0789	Transcriptional regulator
FFA43_RS08920	COG0778	Nitroreductase
FFA43_RS08935	COG1187	pseudouridine synthase activity
FFA43_RS08940	COG0517	IMP dehydrogenase activity
FFA43_RS08940	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FFA43_RS08950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FFA43_RS08955	COG2814	Major facilitator Superfamily
FFA43_RS08960	COG0107	imidazoleglycerol-phosphate synthase activity
FFA43_RS08970	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FFA43_RS08980	COG0564	pseudouridine synthase activity
FFA43_RS08985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FFA43_RS08990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFA43_RS08995	COG0833	amino acid
FFA43_RS09000	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FFA43_RS09055	COG5499	transcription regulator containing HTH domain