locus-tag	class	description
CHLWT_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CHLWT_RS00010	COG0592	DNA-directed DNA polymerase activity
CHLWT_RS00015	COG0187	DNA topoisomerase II activity
CHLWT_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CHLWT_RS00045	COG1749	Flagellar hook protein flgE
CHLWT_RS00050	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CHLWT_RS00080	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CHLWT_RS00085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHLWT_RS00090	COG0268	Binds directly to 16S ribosomal RNA
CHLWT_RS00095	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CHLWT_RS00125	COG2315	Protein conserved in bacteria
CHLWT_RS00135	COG0708	Exodeoxyribonuclease III
CHLWT_RS00140	COG2194	sulfuric ester hydrolase activity
CHLWT_RS00155	COG1971	Probably functions as a manganese efflux pump
CHLWT_RS00165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHLWT_RS00170	COG1121	(ABC) transporter
CHLWT_RS00175	COG0803	Belongs to the bacterial solute-binding protein 9 family
CHLWT_RS00190	COG1858	cytochrome C peroxidase
CHLWT_RS00195	COG5001	Diguanylate cyclase
CHLWT_RS00195	COG3300	MHYT domain
CHLWT_RS00200	COG0288	reversible hydration of carbon dioxide
CHLWT_RS00205	COG0668	transmembrane transport
CHLWT_RS00215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CHLWT_RS00220	COG0571	ribonuclease III activity
CHLWT_RS00225	COG0328	RNA-DNA hybrid ribonuclease activity
CHLWT_RS00235	COG2814	Major facilitator Superfamily
CHLWT_RS00240	COG0358	DNA primase activity
CHLWT_RS00260	COG1556	Lactate utilization protein
CHLWT_RS00265	COG1139	Iron-sulfur cluster binding protein
CHLWT_RS00270	COG0247	lactate metabolic process
CHLWT_RS00275	COG1620	l-lactate permease
CHLWT_RS00280	COG2056	Na+-H+ antiporter family
CHLWT_RS00300	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CHLWT_RS00310	COG3842	ATPase activity
CHLWT_RS00315	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CHLWT_RS00335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHLWT_RS00345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CHLWT_RS00350	COG0367	asparagine synthase
CHLWT_RS00355	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHLWT_RS00375	COG1696	Membrane protein involved in D-alanine export
CHLWT_RS00390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHLWT_RS00425	COG0367	asparagine synthase
CHLWT_RS00435	COG0367	asparagine synthase
CHLWT_RS00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHLWT_RS00485	COG2165	general secretion pathway protein
CHLWT_RS00490	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHLWT_RS00525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CHLWT_RS00535	COG0051	transcription antitermination factor activity, RNA binding
CHLWT_RS00540	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CHLWT_RS00545	COG0088	Forms part of the polypeptide exit tunnel
CHLWT_RS00550	COG0089	rRNA binding
CHLWT_RS00555	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CHLWT_RS00560	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHLWT_RS00565	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CHLWT_RS00570	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CHLWT_RS00575	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CHLWT_RS00585	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CHLWT_RS00590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CHLWT_RS00595	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CHLWT_RS00605	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CHLWT_RS00610	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CHLWT_RS00615	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CHLWT_RS00620	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CHLWT_RS00625	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CHLWT_RS00630	COG0200	Binds to the 23S rRNA
CHLWT_RS00635	COG0201	protein transport
CHLWT_RS00640	COG0024	Methionine aminopeptidase
CHLWT_RS00650	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CHLWT_RS00655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CHLWT_RS00660	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CHLWT_RS00665	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CHLWT_RS00670	COG0202	RNA polymerase activity
CHLWT_RS00675	COG0203	ribosomal protein L17
CHLWT_RS00690	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CHLWT_RS00695	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CHLWT_RS00705	COG0840	transmembrane signaling receptor activity
CHLWT_RS00710	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CHLWT_RS00725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CHLWT_RS00730	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CHLWT_RS00735	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CHLWT_RS00740	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CHLWT_RS00745	COG1840	ABC-type Fe3 transport system, periplasmic component
CHLWT_RS00775	COG1309	transcriptional regulator
CHLWT_RS00780	COG0348	domain, Protein
CHLWT_RS00785	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHLWT_RS00800	COG3260	NADH ubiquinone oxidoreductase 20
CHLWT_RS00805	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHLWT_RS00810	COG3261	NADH dehydrogenase
CHLWT_RS00810	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CHLWT_RS00815	COG0651	ATP synthesis coupled electron transport
CHLWT_RS00820	COG4237	Hydrogenase 4 membrane
CHLWT_RS00825	COG0650	Formate hydrogenlyase subunit 4
CHLWT_RS00830	COG0651	ATP synthesis coupled electron transport
CHLWT_RS00835	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHLWT_RS00845	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CHLWT_RS00850	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CHLWT_RS00855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHLWT_RS00860	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHLWT_RS00860	COG1776	CheC inhibitor of MCP methylation
CHLWT_RS00865	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHLWT_RS00870	COG1191	sigma factor activity
CHLWT_RS00880	COG0455	bacterial-type flagellum organization
CHLWT_RS00885	COG1419	protein localization to endoplasmic reticulum
CHLWT_RS00890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CHLWT_RS00895	COG0006	proline dipeptidase activity
CHLWT_RS00900	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CHLWT_RS00905	COG0402	S-adenosylhomocysteine deaminase activity
CHLWT_RS00910	COG0616	signal peptide processing
CHLWT_RS00915	COG2258	MOSC domain
CHLWT_RS00920	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHLWT_RS00925	COG0287	Prephenate dehydrogenase
CHLWT_RS00935	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CHLWT_RS00945	COG0083	homoserine kinase activity
CHLWT_RS00955	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHLWT_RS00965	COG0779	Required for maturation of 30S ribosomal subunits
CHLWT_RS00985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHLWT_RS00995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHLWT_RS01005	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHLWT_RS01010	COG0113	porphobilinogen synthase activity
CHLWT_RS01015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHLWT_RS01020	COG0357	Ribosomal RNA small subunit methyltransferase G
CHLWT_RS01035	COG0501	Belongs to the peptidase M48B family
CHLWT_RS01040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CHLWT_RS01055	COG2847	Copper chaperone PCu(A)C
CHLWT_RS01060	COG1086	Polysaccharide biosynthesis protein
CHLWT_RS01065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHLWT_RS01070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHLWT_RS01075	COG0602	queuosine metabolic process
CHLWT_RS01080	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHLWT_RS01100	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHLWT_RS01110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CHLWT_RS01125	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CHLWT_RS01130	COG0575	Belongs to the CDS family
CHLWT_RS01155	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CHLWT_RS01160	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHLWT_RS01165	COG0148	phosphopyruvate hydratase activity
CHLWT_RS01190	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHLWT_RS01205	COG0314	molybdopterin synthase activity
CHLWT_RS01210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CHLWT_RS01215	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CHLWT_RS01220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHLWT_RS01225	COG2089	acid synthase
CHLWT_RS01255	COG1083	cytidylyl-transferase
CHLWT_RS01270	COG1921	L-seryl-tRNASec selenium transferase activity
CHLWT_RS01290	COG0243	molybdopterin cofactor binding
CHLWT_RS01295	COG3383	formate dehydrogenase (NAD+) activity
CHLWT_RS01300	COG0437	4 iron, 4 sulfur cluster binding
CHLWT_RS01305	COG1858	cytochrome C peroxidase
CHLWT_RS01310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CHLWT_RS01315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CHLWT_RS01320	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHLWT_RS01335	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHLWT_RS01340	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CHLWT_RS01340	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CHLWT_RS01345	COG1192	Involved in chromosome partitioning
CHLWT_RS01350	COG1475	DNA binding
CHLWT_RS01355	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CHLWT_RS01365	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHLWT_RS01370	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CHLWT_RS01375	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CHLWT_RS01380	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CHLWT_RS01385	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CHLWT_RS01390	COG0811	peptide transport
CHLWT_RS01395	COG0848	biopolymer transport protein
CHLWT_RS01405	COG0823	Involved in the tonB-independent uptake of proteins
CHLWT_RS01410	COG2885	chlorophyll binding
CHLWT_RS01420	COG1047	Peptidyl-prolyl cis-trans
CHLWT_RS01425	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CHLWT_RS01430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHLWT_RS01435	COG0037	tRNA processing
CHLWT_RS01445	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CHLWT_RS01450	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHLWT_RS01455	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHLWT_RS01460	COG0649	NAD binding
CHLWT_RS01470	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CHLWT_RS01475	COG1034	ATP synthesis coupled electron transport
CHLWT_RS01480	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CHLWT_RS01485	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHLWT_RS01490	COG0839	Belongs to the complex I subunit 6 family
CHLWT_RS01495	COG0713	ATP synthesis coupled electron transport
CHLWT_RS01500	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CHLWT_RS01505	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHLWT_RS01510	COG1007	ATP synthesis coupled electron transport
CHLWT_RS01515	COG1854	S-ribosylhomocysteine lyase activity
CHLWT_RS01550	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CHLWT_RS01555	COG1053	succinate dehydrogenase
CHLWT_RS01565	COG0512	Glutamine amidotransferase of anthranilate synthase
CHLWT_RS01565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHLWT_RS01570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CHLWT_RS01575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHLWT_RS01580	COG0471	metal ion transport
CHLWT_RS01585	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CHLWT_RS01595	COG4263	nitrous-oxide reductase activity
CHLWT_RS01610	COG0437	4 iron, 4 sulfur cluster binding
CHLWT_RS01625	COG0348	domain, Protein
CHLWT_RS01630	COG3842	ATPase activity
CHLWT_RS01650	COG0824	Thioesterase
CHLWT_RS01670	COG0004	ammonium transporteR
CHLWT_RS01675	COG0347	Belongs to the P(II) protein family
CHLWT_RS01680	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CHLWT_RS01685	COG0594	ribonuclease P activity
CHLWT_RS01695	COG0706	membrane insertase activity
CHLWT_RS01705	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CHLWT_RS01710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHLWT_RS01715	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CHLWT_RS01720	COG0138	bifunctional purine biosynthesis protein purh
CHLWT_RS01735	COG2151	metal-sulfur cluster biosynthetic enzyme
CHLWT_RS01740	COG0840	transmembrane signaling receptor activity
CHLWT_RS01765	COG0275	rRNA processing
CHLWT_RS01780	COG0849	cell division
CHLWT_RS01785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHLWT_RS01795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHLWT_RS01805	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CHLWT_RS01810	COG0653	protein targeting
CHLWT_RS01815	COG4591	ABC-type transport system involved in lipoprotein release permease component
CHLWT_RS01840	COG2252	PERMEase
CHLWT_RS01845	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CHLWT_RS01855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CHLWT_RS01875	COG0745	RESPONSE REGULATOR receiver
CHLWT_RS01880	COG3301	Polysulphide reductase, NrfD
CHLWT_RS01885	COG0437	4 iron, 4 sulfur cluster binding
CHLWT_RS01890	COG0243	molybdopterin cofactor binding
CHLWT_RS01900	COG0425	Belongs to the sulfur carrier protein TusA family
CHLWT_RS01905	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CHLWT_RS01910	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CHLWT_RS01955	COG2814	Major facilitator Superfamily
CHLWT_RS01965	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHLWT_RS01975	COG0573	inorganic phosphate transmembrane transporter activity
CHLWT_RS01980	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CHLWT_RS01990	COG0372	Belongs to the citrate synthase family
CHLWT_RS01995	COG0475	glutathione-regulated potassium exporter activity
CHLWT_RS01995	COG0569	domain protein
CHLWT_RS02000	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CHLWT_RS02005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHLWT_RS02010	COG1064	alcohol dehydrogenase
CHLWT_RS02020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHLWT_RS02025	COG2244	polysaccharide biosynthetic process
CHLWT_RS02030	COG0438	transferase activity, transferring glycosyl groups
CHLWT_RS02040	COG0438	transferase activity, transferring glycosyl groups
CHLWT_RS02050	COG0438	transferase activity, transferring glycosyl groups
CHLWT_RS02055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHLWT_RS02060	COG0110	maltose O-acetyltransferase activity
CHLWT_RS02070	COG0166	Belongs to the GPI family
CHLWT_RS02085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHLWT_RS02100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHLWT_RS02105	COG0281	malic enzyme
CHLWT_RS02105	COG0280	phosphate acetyltransferase
CHLWT_RS02110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHLWT_RS02130	COG0471	metal ion transport
CHLWT_RS02135	COG0717	Belongs to the dCTP deaminase family
CHLWT_RS02140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CHLWT_RS02145	COG3477	response to acidic pH
CHLWT_RS02150	COG2171	N-acyltransferase activity
CHLWT_RS02155	COG0488	(ABC) transporter
CHLWT_RS02160	COG0019	diaminopimelate decarboxylase activity
CHLWT_RS02170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHLWT_RS02185	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CHLWT_RS02190	COG1086	Polysaccharide biosynthesis protein
CHLWT_RS02200	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CHLWT_RS02205	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CHLWT_RS02210	COG0745	RESPONSE REGULATOR receiver
CHLWT_RS02215	COG2264	protein methyltransferase activity
CHLWT_RS02220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHLWT_RS02230	COG1183	phosphatidylcholine synthase activity
CHLWT_RS02235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHLWT_RS02245	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CHLWT_RS02255	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CHLWT_RS02260	COG1160	GTP binding
CHLWT_RS02265	COG0697	spore germination
CHLWT_RS02280	COG2076	Multidrug Resistance protein
CHLWT_RS02285	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CHLWT_RS02290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHLWT_RS02295	COG0284	orotidine-5'-phosphate decarboxylase activity
CHLWT_RS02330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHLWT_RS02335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CHLWT_RS02350	COG0250	Participates in transcription elongation, termination and antitermination
CHLWT_RS02355	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CHLWT_RS02360	COG0081	regulation of translation
CHLWT_RS02365	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CHLWT_RS02370	COG0222	ribosome binding
CHLWT_RS02375	COG0085	RNA polymerase activity
CHLWT_RS02380	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CHLWT_RS02390	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CHLWT_RS02395	COG0049	tRNA binding
CHLWT_RS02400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHLWT_RS02415	COG0840	transmembrane signaling receptor activity
CHLWT_RS02425	COG2814	Major facilitator Superfamily
CHLWT_RS02440	COG3022	response to hydroperoxide
CHLWT_RS02450	COG0134	indole-3-glycerol-phosphate synthase activity
CHLWT_RS02460	COG0727	PFAM Uncharacterised protein family (UPF0153)
CHLWT_RS02465	COG2813	Specifically methylates the guanine in position
CHLWT_RS02475	COG0492	ferredoxin-NADP+ reductase activity
CHLWT_RS02480	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CHLWT_RS02500	COG0582	viral genome integration into host DNA
CHLWT_RS02555	COG3657	addiction module killer protein
CHLWT_RS02565	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CHLWT_RS02575	COG1230	cation diffusion facilitator family transporter
CHLWT_RS02585	COG0840	transmembrane signaling receptor activity
CHLWT_RS02585	COG5278	phosphoserine phosphatase activity
CHLWT_RS02590	COG0165	Argininosuccinate lyase
CHLWT_RS02595	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CHLWT_RS02600	COG0511	ligase activity, forming carbon-carbon bonds
CHLWT_RS02600	COG5016	pyruvate
CHLWT_RS02605	COG0733	neurotransmitter:sodium symporter activity
CHLWT_RS02620	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHLWT_RS02635	COG1607	acyl-coa hydrolase
CHLWT_RS02640	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHLWT_RS02680	COG2201	protein-glutamate methylesterase activity
CHLWT_RS02685	COG3850	Histidine kinase
CHLWT_RS02685	COG4999	Histidine kinase
CHLWT_RS02685	COG3437	response regulator, receiver
CHLWT_RS02685	COG2205	protein histidine kinase activity
CHLWT_RS02705	COG0519	Catalyzes the synthesis of GMP from XMP
CHLWT_RS02735	COG1185	polyribonucleotide nucleotidyltransferase activity
CHLWT_RS02740	COG0537	adenosine 5'-monophosphoramidase activity
CHLWT_RS02745	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CHLWT_RS02755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CHLWT_RS02760	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CHLWT_RS02765	COG0539	negative regulation of cytoplasmic translation
CHLWT_RS02765	COG1185	polyribonucleotide nucleotidyltransferase activity
CHLWT_RS02775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHLWT_RS02780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CHLWT_RS02790	COG0693	protein deglycase activity
CHLWT_RS02795	COG0724	RNA recognition motif
CHLWT_RS02800	COG0587	DNA-directed DNA polymerase activity
CHLWT_RS02805	COG0672	)-iron permease
CHLWT_RS02830	COG1136	(ABC) transporter
CHLWT_RS02830	COG0577	efflux transmembrane transporter activity
CHLWT_RS02840	COG2957	Belongs to the agmatine deiminase family
CHLWT_RS02845	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CHLWT_RS02855	COG0786	glutamate:sodium symporter activity
CHLWT_RS02865	COG0534	Mate efflux family protein
CHLWT_RS02870	COG2205	protein histidine kinase activity
CHLWT_RS02875	COG0745	RESPONSE REGULATOR receiver
CHLWT_RS02880	COG0659	secondary active sulfate transmembrane transporter activity
CHLWT_RS02895	COG0733	neurotransmitter:sodium symporter activity
CHLWT_RS02900	COG0501	Belongs to the peptidase M48B family
CHLWT_RS02905	COG2890	protein-(glutamine-N5) methyltransferase activity
CHLWT_RS02925	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CHLWT_RS02930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHLWT_RS02950	COG1193	negative regulation of DNA recombination
CHLWT_RS02955	COG3287	FIST C domain
CHLWT_RS02955	COG2200	EAL domain
CHLWT_RS02955	COG2199	diguanylate cyclase activity
CHLWT_RS02965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHLWT_RS02970	COG0579	oxidoreductase
CHLWT_RS02985	COG0612	Peptidase, M16
CHLWT_RS02990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CHLWT_RS02995	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHLWT_RS03000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CHLWT_RS03005	COG0753	catalase activity
CHLWT_RS03020	COG0174	glutamine synthetase
CHLWT_RS03025	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CHLWT_RS03040	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CHLWT_RS03050	COG0752	glycyl-tRNA synthetase alpha subunit
CHLWT_RS03055	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CHLWT_RS03065	COG1519	Transferase
CHLWT_RS03065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CHLWT_RS03070	COG0564	pseudouridine synthase activity
CHLWT_RS03080	COG0310	cobalt ion transport
CHLWT_RS03105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHLWT_RS03135	COG1192	Involved in chromosome partitioning
CHLWT_RS03150	COG2856	Zn peptidase
CHLWT_RS03195	COG2184	nucleotidyltransferase activity
CHLWT_RS03205	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CHLWT_RS03215	COG4786	Flagellar basal body rod
CHLWT_RS03220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHLWT_RS03230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CHLWT_RS03250	COG0191	fructose-bisphosphate aldolase activity
CHLWT_RS03255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHLWT_RS03260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CHLWT_RS03265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CHLWT_RS03365	COG1192	Involved in chromosome partitioning
CHLWT_RS03405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHLWT_RS03450	COG3504	Conjugal transfer protein
CHLWT_RS03465	COG3736	Type IV secretory pathway, component VirB8
CHLWT_RS03510	COG0582	viral genome integration into host DNA
CHLWT_RS03520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHLWT_RS03525	COG0765	amino acid transport
CHLWT_RS03530	COG1126	abc transporter atp-binding protein
CHLWT_RS03545	COG0352	thiamine-phosphate diphosphorylase activity
CHLWT_RS03550	COG1968	undecaprenyl-diphosphatase activity
CHLWT_RS03565	COG0642	Histidine kinase
CHLWT_RS03570	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CHLWT_RS03575	COG0552	protein localization to endoplasmic reticulum
CHLWT_RS03580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHLWT_RS03590	COG1418	mRNA catabolic process
CHLWT_RS03600	COG0586	Pfam SNARE associated Golgi protein
CHLWT_RS03655	COG3646	Phage regulatory protein
CHLWT_RS03665	COG1555	photosystem II stabilization
CHLWT_RS03700	COG1966	Carbon starvation protein
CHLWT_RS03730	COG1053	succinate dehydrogenase
CHLWT_RS03730	COG3976	FMN-binding domain protein
CHLWT_RS03740	COG0471	metal ion transport
CHLWT_RS03750	COG2022	thiamine diphosphate biosynthetic process
CHLWT_RS03760	COG1739	Uncharacterized protein family UPF0029
CHLWT_RS03765	COG0840	transmembrane signaling receptor activity
CHLWT_RS03770	COG0195	Participates in both transcription termination and antitermination
CHLWT_RS03780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHLWT_RS03785	COG2121	Domain of unknown function (DUF374)
CHLWT_RS03805	COG0037	tRNA processing
CHLWT_RS03810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHLWT_RS03815	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CHLWT_RS03820	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CHLWT_RS03860	COG2207	Transcriptional regulator
CHLWT_RS03880	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CHLWT_RS03890	COG2255	four-way junction helicase activity
CHLWT_RS03895	COG0628	permease
CHLWT_RS03900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CHLWT_RS03905	COG1127	ABC transporter
CHLWT_RS03920	COG1338	Plays a role in the flagellum-specific transport system
CHLWT_RS03930	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CHLWT_RS03935	COG0204	Acyl-transferase
CHLWT_RS03945	COG0047	phosphoribosylformylglycinamidine synthase activity
CHLWT_RS03950	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHLWT_RS03955	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CHLWT_RS03960	COG0793	Belongs to the peptidase S41A family
CHLWT_RS03970	COG1131	(ABC) transporter
CHLWT_RS03985	COG0542	response to heat
CHLWT_RS04030	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CHLWT_RS04035	COG0228	four-way junction DNA binding
CHLWT_RS04045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CHLWT_RS04050	COG0336	Belongs to the RNA methyltransferase TrmD family
CHLWT_RS04055	COG0335	large ribosomal subunit rRNA binding
CHLWT_RS04070	COG0424	maF-like protein
CHLWT_RS04080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CHLWT_RS04085	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CHLWT_RS04105	COG1815	bacterial-type flagellum-dependent cell motility
CHLWT_RS04120	COG0542	response to heat
CHLWT_RS04125	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CHLWT_RS04135	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CHLWT_RS04150	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CHLWT_RS04155	COG0210	DNA helicase
CHLWT_RS04175	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CHLWT_RS04180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CHLWT_RS04185	COG0803	Belongs to the bacterial solute-binding protein 9 family
CHLWT_RS04190	COG1121	(ABC) transporter
CHLWT_RS04195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHLWT_RS04200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHLWT_RS04205	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CHLWT_RS04210	COG1862	Preprotein translocase
CHLWT_RS04215	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHLWT_RS04220	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHLWT_RS04230	COG0495	leucyl-tRNA aminoacylation
CHLWT_RS04240	COG3706	GGDEF domain
CHLWT_RS04250	COG0739	heme binding
CHLWT_RS04260	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CHLWT_RS04285	COG1832	CoA-binding protein
CHLWT_RS04290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHLWT_RS04305	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHLWT_RS04310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHLWT_RS04320	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CHLWT_RS04325	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CHLWT_RS04335	COG0101	tRNA pseudouridine synthase activity
CHLWT_RS04340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CHLWT_RS04350	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CHLWT_RS04360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CHLWT_RS04370	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CHLWT_RS04380	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CHLWT_RS04385	COG3959	Transketolase, thiamine diphosphate binding domain
CHLWT_RS04395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHLWT_RS04400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHLWT_RS04410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHLWT_RS04430	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CHLWT_RS04440	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CHLWT_RS04445	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CHLWT_RS04450	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CHLWT_RS04455	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CHLWT_RS04460	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CHLWT_RS04465	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CHLWT_RS04475	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CHLWT_RS04480	COG0298	carbon dioxide binding
CHLWT_RS04495	COG0409	Hydrogenase expression formation protein
CHLWT_RS04500	COG0309	Hydrogenase expression formation protein (HypE)
CHLWT_RS04515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CHLWT_RS04525	COG0137	argininosuccinate synthase activity
CHLWT_RS04530	COG0582	viral genome integration into host DNA
CHLWT_RS04535	COG0772	Belongs to the SEDS family
CHLWT_RS04540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHLWT_RS04565	COG0776	regulation of translation
CHLWT_RS04570	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CHLWT_RS04580	COG1137	ATPase activity
CHLWT_RS04585	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CHLWT_RS04590	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CHLWT_RS04600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHLWT_RS04605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHLWT_RS04610	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHLWT_RS04615	COG1442	glycosyl transferase family 8
CHLWT_RS04615	COG1216	Glycosyl transferase, family 2
CHLWT_RS04620	COG0436	Aminotransferase
CHLWT_RS04625	COG1045	serine acetyltransferase
CHLWT_RS04630	COG1166	arginine decarboxylase activity
CHLWT_RS04635	COG0124	histidyl-tRNA synthetase
CHLWT_RS04640	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CHLWT_RS04645	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CHLWT_RS04660	COG0303	'Molybdopterin
CHLWT_RS04665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHLWT_RS04680	COG2833	Protein of unknown function (DUF455)
CHLWT_RS04695	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CHLWT_RS04705	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CHLWT_RS04720	COG4773	Receptor
CHLWT_RS04730	COG0556	nucleotide-excision repair
CHLWT_RS04755	COG2165	general secretion pathway protein
CHLWT_RS04760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CHLWT_RS04770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHLWT_RS04775	COG0750	zinc metalloprotease
CHLWT_RS04780	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CHLWT_RS04800	COG3962	Belongs to the TPP enzyme family
CHLWT_RS04805	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHLWT_RS04805	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHLWT_RS04815	COG0039	L-malate dehydrogenase activity
CHLWT_RS04835	COG0840	transmembrane signaling receptor activity
CHLWT_RS04840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHLWT_RS04855	COG0343	queuine tRNA-ribosyltransferase activity
CHLWT_RS04865	COG0305	Participates in initiation and elongation during chromosome replication
CHLWT_RS04870	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CHLWT_RS04885	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CHLWT_RS04890	COG1049	propionate catabolic process, 2-methylcitrate cycle
CHLWT_RS04900	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHLWT_RS04900	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHLWT_RS04905	COG0359	binds to the 23S rRNA
CHLWT_RS04910	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CHLWT_RS04915	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CHLWT_RS04920	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CHLWT_RS04940	COG1450	Type ii and iii secretion system protein
CHLWT_RS04960	COG1459	type II secretion system
CHLWT_RS04965	COG1610	YqeY-like protein
CHLWT_RS04990	COG0473	3-isopropylmalate dehydrogenase activity
CHLWT_RS04995	COG0066	3-isopropylmalate dehydratase activity
CHLWT_RS05015	COG0252	asparaginase activity
CHLWT_RS05025	COG0459	protein refolding
CHLWT_RS05030	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHLWT_RS05045	COG2239	Acts as a magnesium transporter
CHLWT_RS05050	COG0739	heme binding
CHLWT_RS05060	COG0277	FAD linked oxidase domain protein
CHLWT_RS05065	COG1295	ribonuclease BN
CHLWT_RS05070	COG0181	hydroxymethylbilane synthase activity
CHLWT_RS05080	COG0442	prolyl-tRNA aminoacylation
CHLWT_RS05085	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CHLWT_RS05090	COG0142	geranyltranstransferase activity
CHLWT_RS05105	COG1674	ftsk spoiiie
CHLWT_RS05105	COG1196	nuclear chromosome segregation
CHLWT_RS05110	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHLWT_RS05120	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CHLWT_RS05125	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CHLWT_RS05145	COG0439	Biotin carboxylase
CHLWT_RS05150	COG3041	Addiction module toxin RelE StbE family
CHLWT_RS05160	COG0326	Molecular chaperone. Has ATPase activity
CHLWT_RS05180	COG0114	fumarate hydratase activity
CHLWT_RS05195	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHLWT_RS05200	COG2011	ABC-type metal ion transport system permease component
CHLWT_RS05205	COG0351	phosphomethylpyrimidine kinase
CHLWT_RS05240	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CHLWT_RS05250	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CHLWT_RS05280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHLWT_RS05285	COG0736	holo-[acyl-carrier-protein] synthase activity
CHLWT_RS05290	COG1580	Controls the rotational direction of flagella during chemotaxis
CHLWT_RS05295	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHLWT_RS05300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHLWT_RS05305	COG2860	membrane
CHLWT_RS05310	COG0642	Histidine kinase
CHLWT_RS05390	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CHLWT_RS05395	COG0788	formyltetrahydrofolate deformylase activity
CHLWT_RS05405	COG0586	Pfam SNARE associated Golgi protein
CHLWT_RS05415	COG0440	acetolactate synthase activity
CHLWT_RS05420	COG0028	Belongs to the TPP enzyme family
CHLWT_RS05425	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CHLWT_RS05430	COG0280	phosphate acetyltransferase
CHLWT_RS05435	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CHLWT_RS05450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHLWT_RS05465	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHLWT_RS05470	COG0632	four-way junction helicase activity
CHLWT_RS05480	COG2201	protein-glutamate methylesterase activity
CHLWT_RS05485	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CHLWT_RS05500	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CHLWT_RS05505	COG0110	maltose O-acetyltransferase activity
CHLWT_RS05520	COG0243	molybdopterin cofactor binding
CHLWT_RS05560	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHLWT_RS05560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHLWT_RS05570	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CHLWT_RS05575	COG0552	protein localization to endoplasmic reticulum
CHLWT_RS05595	COG0728	peptidoglycan biosynthetic process
CHLWT_RS05600	COG0215	cysteine-tRNA ligase activity
CHLWT_RS05605	COG1132	(ABC) transporter
CHLWT_RS05630	COG0167	dihydroorotate dehydrogenase activity
CHLWT_RS05635	COG0612	Peptidase, M16
CHLWT_RS05640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHLWT_RS05645	COG1028	Short-chain dehydrogenase reductase Sdr
CHLWT_RS05650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHLWT_RS05655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHLWT_RS05660	COG0765	amino acid transport
CHLWT_RS05665	COG1126	abc transporter atp-binding protein
CHLWT_RS05680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CHLWT_RS05685	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHLWT_RS05690	COG0352	thiamine-phosphate diphosphorylase activity
CHLWT_RS05695	COG0356	it plays a direct role in the translocation of protons across the membrane
CHLWT_RS05700	COG0730	response to heat
CHLWT_RS05705	COG3263	regulation of cellular component size
CHLWT_RS05715	COG0789	Transcriptional regulator
CHLWT_RS05720	COG0484	heat shock protein binding
CHLWT_RS05730	COG0745	RESPONSE REGULATOR receiver
CHLWT_RS05735	COG0642	Histidine kinase
CHLWT_RS05745	COG1538	Outer membrane efflux protein
CHLWT_RS05750	COG0577	efflux transmembrane transporter activity
CHLWT_RS05750	COG1136	(ABC) transporter
CHLWT_RS05755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHLWT_RS05760	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CHLWT_RS05785	COG2195	Cleaves the N-terminal amino acid of tripeptides
CHLWT_RS05795	COG0500	methyltransferase
CHLWT_RS05805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHLWT_RS05810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CHLWT_RS05815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CHLWT_RS05820	COG1663	tetraacyldisaccharide 4'-kinase activity
CHLWT_RS05825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CHLWT_RS05830	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CHLWT_RS05835	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CHLWT_RS05845	COG2199	diguanylate cyclase activity
CHLWT_RS05845	COG2203	Gaf domain
CHLWT_RS05850	COG3706	GGDEF domain
CHLWT_RS05865	COG0443	Heat shock 70 kDa protein
CHLWT_RS05870	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CHLWT_RS05875	COG1420	regulation of RNA biosynthetic process
CHLWT_RS05890	COG2404	hydrolase activity, acting on ester bonds
CHLWT_RS05895	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHLWT_RS05900	COG1959	2 iron, 2 sulfur cluster binding
CHLWT_RS05905	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CHLWT_RS05910	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CHLWT_RS05915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHLWT_RS06140	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CHLWT_RS06145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CHLWT_RS06150	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CHLWT_RS06155	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CHLWT_RS06220	COG2226	methyltransferase
CHLWT_RS06225	COG0196	riboflavin kinase activity
CHLWT_RS06230	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CHLWT_RS06235	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CHLWT_RS06240	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CHLWT_RS06255	COG0527	aspartate kinase activity
CHLWT_RS06260	COG0494	nUDIX hydrolase
CHLWT_RS06265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHLWT_RS06270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHLWT_RS06275	COG0805	protein transport
CHLWT_RS06280	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHLWT_RS06295	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CHLWT_RS06300	COG0758	DNA mediated transformation
CHLWT_RS06305	COG2861	carbohydrate metabolic process
CHLWT_RS06310	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CHLWT_RS06320	COG0557	exoribonuclease II activity
CHLWT_RS06330	COG0360	Binds together with S18 to 16S ribosomal RNA
CHLWT_RS06335	COG0629	single-stranded DNA binding
CHLWT_RS06340	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CHLWT_RS06345	COG0484	heat shock protein binding
CHLWT_RS06350	COG0745	RESPONSE REGULATOR receiver
CHLWT_RS06355	COG0642	Histidine kinase
CHLWT_RS06365	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHLWT_RS06380	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHLWT_RS06385	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CHLWT_RS06405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHLWT_RS06430	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CHLWT_RS06435	COG1408	metallophosphoesterase
CHLWT_RS06440	COG0688	phosphatidylethanolamine metabolic process
CHLWT_RS06460	COG3043	anaerobic respiration
CHLWT_RS06465	COG0348	domain, Protein
CHLWT_RS06470	COG0437	4 iron, 4 sulfur cluster binding
CHLWT_RS06475	COG0243	molybdopterin cofactor binding
CHLWT_RS06480	COG0012	GTP binding
CHLWT_RS06485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CHLWT_RS06495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHLWT_RS06505	COG0698	ribose 5-phosphate isomerase
CHLWT_RS06510	COG0681	Belongs to the peptidase S26 family
CHLWT_RS06515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CHLWT_RS06525	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CHLWT_RS06550	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHLWT_RS06555	COG0768	penicillin binding
CHLWT_RS06570	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CHLWT_RS06590	COG0131	Imidazoleglycerol-phosphate dehydratase
CHLWT_RS06595	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CHLWT_RS06605	COG0084	hydrolase, TatD family'
CHLWT_RS06615	COG0497	DNA recombination
CHLWT_RS06625	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CHLWT_RS06630	COG0563	adenylate kinase activity
CHLWT_RS06635	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CHLWT_RS06645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHLWT_RS06645	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CHLWT_RS06650	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHLWT_RS06660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHLWT_RS06670	COG1758	RNA polymerase activity
CHLWT_RS06675	COG0528	UMP kinase activity
CHLWT_RS06690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHLWT_RS06695	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CHLWT_RS06705	COG0564	pseudouridine synthase activity
CHLWT_RS06710	COG0772	Belongs to the SEDS family
CHLWT_RS06715	COG1999	signal sequence binding
CHLWT_RS06730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHLWT_RS06735	COG0516	GMP reductase activity
CHLWT_RS06735	COG0517	IMP dehydrogenase activity
CHLWT_RS06740	COG0154	amidase activity
CHLWT_RS06745	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CHLWT_RS06755	COG1058	Belongs to the CinA family
CHLWT_RS06755	COG1546	Belongs to the CinA family
CHLWT_RS06765	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CHLWT_RS06835	COG2217	Heavy metal translocating P-type atpase
CHLWT_RS06855	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CHLWT_RS06860	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CHLWT_RS06865	COG0217	transcriptional regulatory protein
CHLWT_RS06870	COG0716	FMN binding
CHLWT_RS06900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHLWT_RS06905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CHLWT_RS06935	COG3951	Flagellar rod assembly protein muramidase FlgJ
CHLWT_RS06960	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CHLWT_RS06985	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CHLWT_RS07005	COG4106	trans-aconitate 2-methyltransferase activity
CHLWT_RS07010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CHLWT_RS07025	COG0783	Belongs to the Dps family
CHLWT_RS07035	COG0825	malonyl-CoA metabolic process
CHLWT_RS07040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHLWT_RS07045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHLWT_RS07050	COG1028	Short-chain dehydrogenase reductase Sdr
CHLWT_RS07065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHLWT_RS07070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CHLWT_RS07080	COG0582	viral genome integration into host DNA
CHLWT_RS07120	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CHLWT_RS07135	COG1793	dna ligase
CHLWT_RS07145	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CHLWT_RS07155	COG1560	Kdo2-lipid A biosynthetic process
CHLWT_RS07165	COG0438	transferase activity, transferring glycosyl groups
CHLWT_RS07175	COG0726	polysaccharide deacetylase
CHLWT_RS07195	COG0438	transferase activity, transferring glycosyl groups
CHLWT_RS07200	COG0726	polysaccharide deacetylase
CHLWT_RS07205	COG0463	Glycosyl transferase, family 2
CHLWT_RS07210	COG0438	transferase activity, transferring glycosyl groups
CHLWT_RS07230	COG2217	Heavy metal translocating P-type atpase
CHLWT_RS07235	COG0656	L-ascorbic acid biosynthetic process
CHLWT_RS07240	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CHLWT_RS07260	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CHLWT_RS07265	COG0149	triose-phosphate isomerase activity
CHLWT_RS07270	COG0126	phosphoglycerate kinase activity
CHLWT_RS07275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CHLWT_RS07280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CHLWT_RS07285	COG2855	membrane
CHLWT_RS07290	COG0018	arginyl-trna synthetase
CHLWT_RS07295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHLWT_RS07310	COG1684	flagellar biosynthetic protein fliR
CHLWT_RS07315	COG1136	(ABC) transporter
CHLWT_RS07320	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CHLWT_RS07325	COG0052	Belongs to the universal ribosomal protein uS2 family
CHLWT_RS07345	COG0445	tRNA wobble uridine modification
CHLWT_RS07350	COG0723	plastoquinol--plastocyanin reductase activity
CHLWT_RS07380	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CHLWT_RS07390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CHLWT_RS07420	COG0140	phosphoribosyl-ATP diphosphatase activity
CHLWT_RS07420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CHLWT_RS07435	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CHLWT_RS07440	COG4797	methyltransferase
CHLWT_RS07440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CHLWT_RS07445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CHLWT_RS07455	COG0492	ferredoxin-NADP+ reductase activity
CHLWT_RS07460	COG3118	belongs to the thioredoxin family
CHLWT_RS07465	COG0792	nuclease activity
CHLWT_RS07470	COG0460	homoserine dehydrogenase
CHLWT_RS07475	COG0436	Aminotransferase
CHLWT_RS07490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHLWT_RS07495	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CHLWT_RS07500	COG0254	rRNA binding
CHLWT_RS07525	COG0848	biopolymer transport protein
CHLWT_RS07530	COG0811	peptide transport
CHLWT_RS07540	COG1120	ATPase activity
CHLWT_RS07545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHLWT_RS07555	COG4774	siderophore transport
CHLWT_RS07560	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CHLWT_RS07575	COG0019	diaminopimelate decarboxylase activity
CHLWT_RS07590	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHLWT_RS07595	COG1766	The M ring may be actively involved in energy transduction
CHLWT_RS07600	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHLWT_RS07610	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CHLWT_RS07620	COG0842	Transport permease protein
CHLWT_RS07625	COG0842	Transport permease protein
CHLWT_RS07630	COG1131	(ABC) transporter
CHLWT_RS07650	COG1570	exodeoxyribonuclease VII activity
CHLWT_RS07665	COG0450	alkyl hydroperoxide reductase
CHLWT_RS07670	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CHLWT_RS07675	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CHLWT_RS07690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHLWT_RS07705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHLWT_RS07715	COG0745	RESPONSE REGULATOR receiver
CHLWT_RS07725	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CHLWT_RS07735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHLWT_RS07740	COG0416	fatty acid biosynthetic process
CHLWT_RS07745	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CHLWT_RS07755	COG0105	UTP biosynthetic process
CHLWT_RS07765	COG1360	Flagellar Motor Protein
CHLWT_RS07770	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CHLWT_RS07805	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHLWT_RS07810	COG0778	Nitroreductase
CHLWT_RS07815	COG0709	Synthesizes selenophosphate from selenide and ATP
CHLWT_RS07830	COG0193	aminoacyl-tRNA hydrolase activity
CHLWT_RS07835	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CHLWT_RS07845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CHLWT_RS07855	COG0835	chemotaxis
CHLWT_RS07860	COG2198	Histidine kinase
CHLWT_RS07860	COG0784	Response regulator, receiver
CHLWT_RS07860	COG0643	Histidine kinase
CHLWT_RS07865	COG0835	chemotaxis
CHLWT_RS07865	COG0784	Response regulator, receiver
CHLWT_RS07880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHLWT_RS07890	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CHLWT_RS07925	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHLWT_RS07935	COG1077	Cell shape determining protein MreB Mrl
CHLWT_RS07940	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CHLWT_RS07945	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CHLWT_RS07950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CHLWT_RS07955	COG1064	alcohol dehydrogenase
CHLWT_RS07970	COG0731	radical SAM domain protein
CHLWT_RS07975	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHLWT_RS07985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CHLWT_RS08000	COG0482	sulfurtransferase activity
CHLWT_RS08010	COG1611	Belongs to the LOG family
CHLWT_RS08015	COG0493	'glutamate synthase
CHLWT_RS08020	COG0067	glutamate synthase
CHLWT_RS08020	COG0069	glutamate synthase activity
CHLWT_RS08020	COG0070	glutamate synthase
CHLWT_RS08025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CHLWT_RS08025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CHLWT_RS08030	COG0489	protein tyrosine kinase activity
CHLWT_RS08035	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CHLWT_RS08040	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CHLWT_RS08040	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CHLWT_RS08045	COG0745	RESPONSE REGULATOR receiver
CHLWT_RS08055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CHLWT_RS08065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHLWT_RS08065	COG1333	cytochrome c biogenesis protein
CHLWT_RS08090	COG0683	leucine binding
CHLWT_RS08095	COG2010	Cytochrome c
CHLWT_RS08100	COG4773	Receptor
CHLWT_RS08105	COG4773	Receptor
CHLWT_RS08120	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHLWT_RS08120	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHLWT_RS08120	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHLWT_RS08120	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHLWT_RS08130	COG0668	transmembrane transport
CHLWT_RS08140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CHLWT_RS08145	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CHLWT_RS08150	COG0210	DNA helicase
CHLWT_RS08195	COG3278	Belongs to the heme-copper respiratory oxidase family
CHLWT_RS08200	COG0745	RESPONSE REGULATOR receiver
CHLWT_RS08205	COG0840	transmembrane signaling receptor activity
CHLWT_RS08215	COG0505	Belongs to the CarA family
CHLWT_RS08235	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CHLWT_RS08240	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CHLWT_RS08245	COG3300	MHYT domain
CHLWT_RS08245	COG5001	Diguanylate cyclase
CHLWT_RS08275	COG3585	molybdate ion transport
CHLWT_RS08310	COG1776	CheC inhibitor of MCP methylation
CHLWT_RS08310	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHLWT_RS08325	COG0133	tryptophan synthase activity
CHLWT_RS08330	COG0135	phosphoribosylanthranilate isomerase activity
CHLWT_RS08330	COG0134	indole-3-glycerol-phosphate synthase activity
CHLWT_RS08340	COG1733	regulation of RNA biosynthetic process
CHLWT_RS08355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHLWT_RS08370	COG2204	response regulator
CHLWT_RS08400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHLWT_RS08415	COG4310	Domain of unknown function (DUF2172)
CHLWT_RS08435	COG1942	4-Oxalocrotonate Tautomerase
CHLWT_RS08440	COG0481	GTPase activity
CHLWT_RS08460	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CHLWT_RS08465	COG0540	Belongs to the ATCase OTCase family
CHLWT_RS08530	COG3468	outer membrane autotransporter barrel domain protein
CHLWT_RS08560	COG1116	anion transmembrane transporter activity
CHLWT_RS08625	COG0811	peptide transport
CHLWT_RS08635	COG4771	TonB-dependent receptor
CHLWT_RS08655	COG0748	coenzyme F420 binding
CHLWT_RS08660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHLWT_RS08665	COG1120	ATPase activity
CHLWT_RS08670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHLWT_RS08705	COG0501	Belongs to the peptidase M48B family
CHLWT_RS08710	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CHLWT_RS08720	COG1253	flavin adenine dinucleotide binding
CHLWT_RS08755	COG2703	oxygen carrier activity
CHLWT_RS08770	COG1104	cysteine desulfurase activity
CHLWT_RS08775	COG1157	protein secretion by the type III secretion system
CHLWT_RS08785	COG0544	peptidyl-prolyl cis-trans isomerase activity
CHLWT_RS08790	COG0740	serine-type endopeptidase activity
CHLWT_RS08800	COG0242	peptide deformylase activity
CHLWT_RS08805	COG0606	chelatase, subunit chli
CHLWT_RS08810	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CHLWT_RS08810	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CHLWT_RS08815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CHLWT_RS08820	COG0861	Integral membrane protein TerC family
CHLWT_RS08885	COG0848	biopolymer transport protein
CHLWT_RS08890	COG0811	peptide transport
CHLWT_RS08895	COG4771	TonB-dependent receptor
CHLWT_RS08920	COG0754	glutathionylspermidine amidase activity
CHLWT_RS08925	COG0163	prenyltransferase activity
CHLWT_RS08930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHLWT_RS08935	COG1666	GTP binding
CHLWT_RS08945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHLWT_RS08960	COG0318	PFAM AMP-dependent synthetase and ligase
CHLWT_RS08970	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CHLWT_RS08985	COG0730	response to heat
CHLWT_RS08990	COG0628	permease
CHLWT_RS09005	COG1027	Aspartate ammonia-lyase
CHLWT_RS09020	COG0129	dihydroxy-acid dehydratase activity
CHLWT_RS09035	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CHLWT_RS09040	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CHLWT_RS09045	COG0748	coenzyme F420 binding
CHLWT_RS09060	COG1749	Flagellar hook protein flgE
CHLWT_RS09075	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CHLWT_RS09080	COG0237	dephospho-CoA kinase activity
CHLWT_RS09100	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHLWT_RS09100	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CHLWT_RS09105	COG0697	spore germination
CHLWT_RS09110	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CHLWT_RS09120	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CHLWT_RS09125	COG0233	cytoplasmic translational termination
CHLWT_RS09135	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHLWT_RS09140	COG0670	Belongs to the BI1 family
CHLWT_RS09145	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHLWT_RS09190	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHLWT_RS09200	COG0300	oxidoreductase activity
CHLWT_RS09210	COG0656	L-ascorbic acid biosynthetic process
CHLWT_RS09215	COG0789	Transcriptional regulator
CHLWT_RS09225	COG0778	Nitroreductase
CHLWT_RS09245	COG1187	pseudouridine synthase activity
CHLWT_RS09260	COG0517	IMP dehydrogenase activity
CHLWT_RS09260	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CHLWT_RS09270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHLWT_RS09275	COG2814	Major facilitator Superfamily
CHLWT_RS09280	COG0107	imidazoleglycerol-phosphate synthase activity
CHLWT_RS09290	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CHLWT_RS09300	COG0564	pseudouridine synthase activity
CHLWT_RS09305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CHLWT_RS09310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHLWT_RS09315	COG0833	amino acid
CHLWT_RS09320	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group