locus-tag	class	description
BKM79_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BKM79_RS00015	COG0187	DNA topoisomerase II activity
BKM79_RS00030	COG2056	Na+-H+ antiporter family
BKM79_RS00035	COG0069	glutamate synthase activity
BKM79_RS00035	COG0070	glutamate synthase
BKM79_RS00035	COG0067	glutamate synthase
BKM79_RS00045	COG0493	'glutamate synthase
BKM79_RS00050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKM79_RS00060	COG1592	Rubrerythrin
BKM79_RS00065	COG0129	dihydroxy-acid dehydratase activity
BKM79_RS00070	COG3477	response to acidic pH
BKM79_RS00080	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BKM79_RS00095	COG0840	transmembrane signaling receptor activity
BKM79_RS00100	COG1858	cytochrome C peroxidase
BKM79_RS00105	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKM79_RS00115	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKM79_RS00120	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKM79_RS00195	COG2814	Major facilitator Superfamily
BKM79_RS00215	COG1217	gtp-binding protein TYPA
BKM79_RS00230	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BKM79_RS00260	COG0471	metal ion transport
BKM79_RS00265	COG0471	metal ion transport
BKM79_RS00280	COG0471	metal ion transport
BKM79_RS00285	COG0471	metal ion transport
BKM79_RS00290	COG0482	sulfurtransferase activity
BKM79_RS00320	COG1776	CheC inhibitor of MCP methylation
BKM79_RS00320	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKM79_RS00325	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKM79_RS00330	COG1191	sigma factor activity
BKM79_RS00340	COG0455	bacterial-type flagellum organization
BKM79_RS00345	COG1419	protein localization to endoplasmic reticulum
BKM79_RS00350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BKM79_RS00355	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BKM79_RS00360	COG0402	S-adenosylhomocysteine deaminase activity
BKM79_RS00365	COG0616	signal peptide processing
BKM79_RS00385	COG1139	Iron-sulfur cluster binding protein
BKM79_RS00390	COG0247	lactate metabolic process
BKM79_RS00405	COG3021	interspecies interaction between organisms
BKM79_RS00420	COG1271	oxidase subunit
BKM79_RS00425	COG1294	oxidase, subunit
BKM79_RS00430	COG1794	racemase activity, acting on amino acids and derivatives
BKM79_RS00435	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BKM79_RS00440	COG1027	Aspartate ammonia-lyase
BKM79_RS00445	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BKM79_RS00475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BKM79_RS00480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BKM79_RS00485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BKM79_RS00500	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BKM79_RS00500	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BKM79_RS00505	COG1192	Involved in chromosome partitioning
BKM79_RS00510	COG1475	DNA binding
BKM79_RS00525	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKM79_RS00540	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BKM79_RS00545	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BKM79_RS00550	COG0811	peptide transport
BKM79_RS00555	COG0848	biopolymer transport protein
BKM79_RS00565	COG0823	Involved in the tonB-independent uptake of proteins
BKM79_RS00570	COG2885	chlorophyll binding
BKM79_RS00580	COG1047	Peptidyl-prolyl cis-trans
BKM79_RS00585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKM79_RS00590	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BKM79_RS00595	COG0037	tRNA processing
BKM79_RS00630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BKM79_RS00635	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BKM79_RS00640	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BKM79_RS00675	COG0083	homoserine kinase activity
BKM79_RS00700	COG1401	restriction endodeoxyribonuclease activity
BKM79_RS00715	COG1121	(ABC) transporter
BKM79_RS00735	COG0492	ferredoxin-NADP+ reductase activity
BKM79_RS00740	COG3118	belongs to the thioredoxin family
BKM79_RS00745	COG0792	nuclease activity
BKM79_RS00755	COG0436	Aminotransferase
BKM79_RS00775	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BKM79_RS00785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BKM79_RS00805	COG0602	queuosine metabolic process
BKM79_RS00835	COG1971	Probably functions as a manganese efflux pump
BKM79_RS00850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BKM79_RS00880	COG1840	ABC-type Fe3 transport system, periplasmic component
BKM79_RS00895	COG1629	transport
BKM79_RS00895	COG4206	TonB-dependent receptor
BKM79_RS00900	COG0811	peptide transport
BKM79_RS00905	COG0848	biopolymer transport protein
BKM79_RS00920	COG1253	flavin adenine dinucleotide binding
BKM79_RS00930	COG2824	Alkylphosphonate utilization operon protein PhnA
BKM79_RS00935	COG0861	Integral membrane protein TerC family
BKM79_RS00940	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BKM79_RS00945	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BKM79_RS00945	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BKM79_RS00955	COG0606	chelatase, subunit chli
BKM79_RS00960	COG0242	peptide deformylase activity
BKM79_RS00970	COG0544	peptidyl-prolyl cis-trans isomerase activity
BKM79_RS00975	COG0302	gtp cyclohydrolase
BKM79_RS00980	COG1157	protein secretion by the type III secretion system
BKM79_RS00985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BKM79_RS00995	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BKM79_RS00995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BKM79_RS01050	COG2851	Citrate transporter
BKM79_RS01055	COG1297	OPT oligopeptide transporter protein
BKM79_RS01060	COG1968	undecaprenyl-diphosphatase activity
BKM79_RS01065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKM79_RS01070	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BKM79_RS01115	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BKM79_RS01125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BKM79_RS01130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKM79_RS01140	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BKM79_RS01150	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKM79_RS01160	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BKM79_RS01165	COG0233	cytoplasmic translational termination
BKM79_RS01170	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKM79_RS01175	COG0670	Belongs to the BI1 family
BKM79_RS01180	COG0288	reversible hydration of carbon dioxide
BKM79_RS01185	COG0668	transmembrane transport
BKM79_RS01210	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BKM79_RS01215	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BKM79_RS01220	COG0840	transmembrane signaling receptor activity
BKM79_RS01220	COG3290	protein histidine kinase activity
BKM79_RS01245	COG0477	Major facilitator Superfamily
BKM79_RS01255	COG0315	cyclic pyranopterin monophosphate synthase activity
BKM79_RS01260	COG2921	Belongs to the UPF0250 family
BKM79_RS01270	COG0708	Exodeoxyribonuclease III
BKM79_RS01275	COG2194	sulfuric ester hydrolase activity
BKM79_RS01280	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BKM79_RS01290	COG0418	dihydroorotase activity
BKM79_RS01300	COG2226	methyltransferase
BKM79_RS01310	COG0428	transporter
BKM79_RS01315	COG0243	molybdopterin cofactor binding
BKM79_RS01335	COG0330	HflC and HflK could
BKM79_RS01345	COG1942	4-Oxalocrotonate Tautomerase
BKM79_RS01350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BKM79_RS01355	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BKM79_RS01360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKM79_RS01365	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKM79_RS01370	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BKM79_RS01375	COG1077	Cell shape determining protein MreB Mrl
BKM79_RS01385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKM79_RS01405	COG0835	chemotaxis
BKM79_RS01410	COG0784	Response regulator, receiver
BKM79_RS01410	COG2198	Histidine kinase
BKM79_RS01410	COG0643	Histidine kinase
BKM79_RS01415	COG0835	chemotaxis
BKM79_RS01415	COG0784	Response regulator, receiver
BKM79_RS01430	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKM79_RS01455	COG0454	-acetyltransferase
BKM79_RS01500	COG4106	trans-aconitate 2-methyltransferase activity
BKM79_RS01515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKM79_RS01520	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BKM79_RS01525	COG2076	Multidrug Resistance protein
BKM79_RS01550	COG0019	diaminopimelate decarboxylase activity
BKM79_RS01565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKM79_RS01575	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKM79_RS01600	COG2226	methyltransferase
BKM79_RS01605	COG1570	exodeoxyribonuclease VII activity
BKM79_RS01610	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BKM79_RS01615	COG0251	oxidation-reduction process
BKM79_RS01620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKM79_RS01630	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BKM79_RS01640	COG0105	UTP biosynthetic process
BKM79_RS01650	COG0450	alkyl hydroperoxide reductase
BKM79_RS01660	COG1360	Flagellar Motor Protein
BKM79_RS01665	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BKM79_RS01675	COG0477	Major facilitator Superfamily
BKM79_RS01685	COG1238	metal cluster binding
BKM79_RS01690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKM79_RS01710	COG0512	Glutamine amidotransferase of anthranilate synthase
BKM79_RS01710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BKM79_RS01720	COG0133	tryptophan synthase activity
BKM79_RS01735	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKM79_RS01735	COG1776	CheC inhibitor of MCP methylation
BKM79_RS01750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BKM79_RS01755	COG0745	RESPONSE REGULATOR receiver
BKM79_RS01765	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BKM79_RS01780	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BKM79_RS01785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKM79_RS01795	COG1538	Outer membrane efflux protein
BKM79_RS01805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKM79_RS01820	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BKM79_RS01835	COG0754	glutathionylspermidine amidase activity
BKM79_RS01840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKM79_RS01845	COG1666	GTP binding
BKM79_RS01860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKM79_RS01865	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BKM79_RS01870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKM79_RS01880	COG0284	orotidine-5'-phosphate decarboxylase activity
BKM79_RS01890	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BKM79_RS01935	COG0469	pyruvate kinase activity
BKM79_RS01945	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BKM79_RS01980	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BKM79_RS01985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKM79_RS02000	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKM79_RS02020	COG1053	succinate dehydrogenase
BKM79_RS02025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BKM79_RS02105	COG0488	(ABC) transporter
BKM79_RS02120	COG1739	Uncharacterized protein family UPF0029
BKM79_RS02160	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BKM79_RS02165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKM79_RS02170	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BKM79_RS02180	COG1028	Short-chain dehydrogenase reductase Sdr
BKM79_RS02190	COG1053	succinate dehydrogenase
BKM79_RS02195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BKM79_RS02200	COG2048	Heterodisulfide reductase, subunit B
BKM79_RS02205	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BKM79_RS02210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKM79_RS02215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKM79_RS02220	COG0825	malonyl-CoA metabolic process
BKM79_RS02225	COG4771	TonB-dependent receptor
BKM79_RS02235	COG4771	TonB-dependent receptor
BKM79_RS02255	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BKM79_RS02260	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BKM79_RS02290	COG2121	Domain of unknown function (DUF374)
BKM79_RS02295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKM79_RS02305	COG0195	Participates in both transcription termination and antitermination
BKM79_RS02315	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BKM79_RS02320	COG0612	Peptidase, M16
BKM79_RS02325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BKM79_RS02330	COG2346	COG2346, Truncated hemoglobins
BKM79_RS02345	COG0765	amino acid transport
BKM79_RS02395	COG0250	Participates in transcription elongation, termination and antitermination
BKM79_RS02400	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BKM79_RS02405	COG0081	regulation of translation
BKM79_RS02410	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BKM79_RS02415	COG0222	ribosome binding
BKM79_RS02420	COG0085	RNA polymerase activity
BKM79_RS02435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKM79_RS02445	COG2721	sulfolactate sulfo-lyase activity
BKM79_RS02455	COG1028	Short-chain dehydrogenase reductase Sdr
BKM79_RS02460	COG0738	Major facilitator superfamily
BKM79_RS02480	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BKM79_RS02485	COG0049	tRNA binding
BKM79_RS02530	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BKM79_RS02545	COG0673	inositol 2-dehydrogenase activity
BKM79_RS02560	COG0424	maF-like protein
BKM79_RS02575	COG1937	Protein conserved in bacteria
BKM79_RS02580	COG0793	Belongs to the peptidase S41A family
BKM79_RS02595	COG0047	phosphoribosylformylglycinamidine synthase activity
BKM79_RS02605	COG0204	Acyl-transferase
BKM79_RS02620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKM79_RS02640	COG1677	Flagellar hook-basal body complex protein FliE
BKM79_RS02645	COG1558	bacterial-type flagellum-dependent cell motility
BKM79_RS02650	COG1815	bacterial-type flagellum-dependent cell motility
BKM79_RS02670	COG0039	L-malate dehydrogenase activity
BKM79_RS02680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BKM79_RS02690	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BKM79_RS02690	COG0674	pyruvate-flavodoxin oxidoreductase activity
BKM79_RS02695	COG1013	pyruvate-flavodoxin oxidoreductase activity
BKM79_RS02715	COG0142	geranyltranstransferase activity
BKM79_RS02735	COG0181	hydroxymethylbilane synthase activity
BKM79_RS02750	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BKM79_RS02770	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BKM79_RS02800	COG1289	transmembrane transporter activity
BKM79_RS02805	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BKM79_RS02810	COG0492	ferredoxin-NADP+ reductase activity
BKM79_RS02825	COG0305	Participates in initiation and elongation during chromosome replication
BKM79_RS02840	COG4735	regulation of single-species biofilm formation
BKM79_RS02845	COG4735	regulation of single-species biofilm formation
BKM79_RS02895	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKM79_RS02895	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKM79_RS02900	COG1610	YqeY-like protein
BKM79_RS02905	COG0028	Belongs to the TPP enzyme family
BKM79_RS02910	COG0440	acetolactate synthase activity
BKM79_RS02920	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BKM79_RS02925	COG0805	protein transport
BKM79_RS02935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKM79_RS02940	COG0494	nUDIX hydrolase
BKM79_RS02945	COG0527	aspartate kinase activity
BKM79_RS02960	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BKM79_RS02965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKM79_RS02980	COG0196	riboflavin kinase activity
BKM79_RS02985	COG2890	protein-(glutamine-N5) methyltransferase activity
BKM79_RS03000	COG2860	membrane
BKM79_RS03010	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BKM79_RS03015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKM79_RS03045	COG2258	MOSC domain
BKM79_RS03065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKM79_RS03075	COG1538	Outer membrane efflux protein
BKM79_RS03095	COG1696	Membrane protein involved in D-alanine export
BKM79_RS03100	COG1528	Iron-storage protein
BKM79_RS03105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BKM79_RS03110	COG0573	inorganic phosphate transmembrane transporter activity
BKM79_RS03115	COG0581	inorganic phosphate transmembrane transporter activity
BKM79_RS03130	COG0534	Mate efflux family protein
BKM79_RS03155	COG0298	carbon dioxide binding
BKM79_RS03165	COG0309	Hydrogenase expression formation protein (HypE)
BKM79_RS03170	COG0375	protein maturation
BKM79_RS03185	COG0557	exoribonuclease II activity
BKM79_RS03190	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BKM79_RS03220	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BKM79_RS03225	COG0563	adenylate kinase activity
BKM79_RS03230	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BKM79_RS03240	COG0497	DNA recombination
BKM79_RS03250	COG0084	hydrolase, TatD family'
BKM79_RS03255	COG0791	NLP P60 protein
BKM79_RS03255	COG1388	LysM domain
BKM79_RS03260	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BKM79_RS03280	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BKM79_RS03325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BKM79_RS03330	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BKM79_RS03345	COG0137	argininosuccinate synthase activity
BKM79_RS03350	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BKM79_RS03355	COG0802	atpase or kinase
BKM79_RS03360	COG1137	ATPase activity
BKM79_RS03365	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BKM79_RS03370	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BKM79_RS03390	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BKM79_RS03430	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BKM79_RS03440	COG0280	phosphate acetyltransferase
BKM79_RS03465	COG0275	rRNA processing
BKM79_RS03475	COG0849	cell division
BKM79_RS03480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BKM79_RS03485	COG4786	Flagellar basal body rod
BKM79_RS03490	COG4786	Flagellar basal body rod
BKM79_RS03505	COG0826	peptidase U32
BKM79_RS03510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BKM79_RS03520	COG0752	glycyl-tRNA synthetase alpha subunit
BKM79_RS03540	COG0564	pseudouridine synthase activity
BKM79_RS03545	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BKM79_RS03550	COG0228	four-way junction DNA binding
BKM79_RS03555	COG1837	Belongs to the UPF0109 family
BKM79_RS03565	COG0336	Belongs to the RNA methyltransferase TrmD family
BKM79_RS03580	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BKM79_RS03585	COG1393	Belongs to the ArsC family
BKM79_RS03595	COG0587	DNA-directed DNA polymerase activity
BKM79_RS03615	COG2890	protein-(glutamine-N5) methyltransferase activity
BKM79_RS03630	COG0521	Mo-molybdopterin cofactor biosynthetic process
BKM79_RS03655	COG1178	ABC-type Fe3 transport system permease component
BKM79_RS03755	COG4771	TonB-dependent receptor
BKM79_RS03760	COG1420	regulation of RNA biosynthetic process
BKM79_RS03765	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BKM79_RS03790	COG0436	Aminotransferase
BKM79_RS03795	COG1045	serine acetyltransferase
BKM79_RS03800	COG1166	arginine decarboxylase activity
BKM79_RS03815	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BKM79_RS03820	COG0163	prenyltransferase activity
BKM79_RS03830	COG1464	Belongs to the NlpA lipoprotein family
BKM79_RS03835	COG1464	Belongs to the NlpA lipoprotein family
BKM79_RS03840	COG1464	Belongs to the NlpA lipoprotein family
BKM79_RS03845	COG2011	ABC-type metal ion transport system permease component
BKM79_RS03850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKM79_RS03865	COG0210	DNA helicase
BKM79_RS03875	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BKM79_RS03890	COG0348	domain, Protein
BKM79_RS03895	COG3043	anaerobic respiration
BKM79_RS03930	COG0788	formyltetrahydrofolate deformylase activity
BKM79_RS03935	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BKM79_RS03945	COG0642	Histidine kinase
BKM79_RS03970	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKM79_RS03990	COG0215	cysteine-tRNA ligase activity
BKM79_RS03995	COG1132	(ABC) transporter
BKM79_RS04000	COG0167	dihydroorotate dehydrogenase activity
BKM79_RS04010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKM79_RS04015	COG1028	Short-chain dehydrogenase reductase Sdr
BKM79_RS04030	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BKM79_RS04040	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BKM79_RS04045	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BKM79_RS04060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKM79_RS04075	COG1338	Plays a role in the flagellum-specific transport system
BKM79_RS04110	COG0101	tRNA pseudouridine synthase activity
BKM79_RS04115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKM79_RS04135	COG1757	Na H antiporter
BKM79_RS04140	COG4221	oxidoreductase activity
BKM79_RS04150	COG1049	propionate catabolic process, 2-methylcitrate cycle
BKM79_RS04155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKM79_RS04165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKM79_RS04165	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKM79_RS04175	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BKM79_RS04200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKM79_RS04205	COG1408	metallophosphoesterase
BKM79_RS04210	COG0688	phosphatidylethanolamine metabolic process
BKM79_RS04255	COG0681	Belongs to the peptidase S26 family
BKM79_RS04260	COG0303	'Molybdopterin
BKM79_RS04275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BKM79_RS04275	COG0512	Glutamine amidotransferase of anthranilate synthase
BKM79_RS04285	COG0582	viral genome integration into host DNA
BKM79_RS04295	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BKM79_RS04335	COG2404	hydrolase activity, acting on ester bonds
BKM79_RS04340	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKM79_RS04345	COG1959	2 iron, 2 sulfur cluster binding
BKM79_RS04350	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BKM79_RS04360	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKM79_RS04385	COG0745	RESPONSE REGULATOR receiver
BKM79_RS04390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKM79_RS04400	COG1185	polyribonucleotide nucleotidyltransferase activity
BKM79_RS04400	COG0539	negative regulation of cytoplasmic translation
BKM79_RS04405	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BKM79_RS04410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BKM79_RS04420	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BKM79_RS04425	COG0537	adenosine 5'-monophosphoramidase activity
BKM79_RS04440	COG0765	amino acid transport
BKM79_RS04450	COG1115	amino acid carrier protein
BKM79_RS04455	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BKM79_RS04460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BKM79_RS04485	COG1999	signal sequence binding
BKM79_RS04495	COG0776	regulation of translation
BKM79_RS04515	COG1966	Carbon starvation protein
BKM79_RS04520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BKM79_RS04525	COG0765	amino acid transport
BKM79_RS04530	COG0765	amino acid transport
BKM79_RS04540	COG1126	abc transporter atp-binding protein
BKM79_RS04545	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BKM79_RS04550	COG2201	protein-glutamate methylesterase activity
BKM79_RS04565	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKM79_RS04580	COG0012	GTP binding
BKM79_RS04585	COG0165	Argininosuccinate lyase
BKM79_RS04590	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BKM79_RS04595	COG0511	ligase activity, forming carbon-carbon bonds
BKM79_RS04595	COG5016	pyruvate
BKM79_RS04600	COG0733	neurotransmitter:sodium symporter activity
BKM79_RS04605	COG0733	neurotransmitter:sodium symporter activity
BKM79_RS04670	COG0765	amino acid transport
BKM79_RS04680	COG0653	protein targeting
BKM79_RS04685	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BKM79_RS04695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BKM79_RS04710	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BKM79_RS04725	COG0840	transmembrane signaling receptor activity
BKM79_RS04735	COG0138	bifunctional purine biosynthesis protein purh
BKM79_RS04740	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BKM79_RS04745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKM79_RS04760	COG0706	membrane insertase activity
BKM79_RS04765	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BKM79_RS04775	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BKM79_RS04795	COG0824	Thioesterase
BKM79_RS04830	COG0500	methyltransferase
BKM79_RS04850	COG2195	Cleaves the N-terminal amino acid of tripeptides
BKM79_RS04860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKM79_RS04870	COG3022	response to hydroperoxide
BKM79_RS04875	COG1473	amidohydrolase
BKM79_RS04905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKM79_RS04915	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKM79_RS04920	COG0113	porphobilinogen synthase activity
BKM79_RS04925	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKM79_RS04930	COG0357	Ribosomal RNA small subunit methyltransferase G
BKM79_RS04940	COG2855	membrane
BKM79_RS04945	COG0583	DNA-binding transcription factor activity
BKM79_RS04950	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKM79_RS04970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKM79_RS05015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKM79_RS05015	COG1333	cytochrome c biogenesis protein
BKM79_RS05070	COG2204	response regulator
BKM79_RS05125	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BKM79_RS05135	COG0439	Biotin carboxylase
BKM79_RS05165	COG0352	thiamine-phosphate diphosphorylase activity
BKM79_RS05170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BKM79_RS05200	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKM79_RS05240	COG0516	GMP reductase activity
BKM79_RS05240	COG0517	IMP dehydrogenase activity
BKM79_RS05245	COG0154	amidase activity
BKM79_RS05255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BKM79_RS05265	COG0456	acetyltransferase
BKM79_RS05270	COG0778	Nitroreductase
BKM79_RS05285	COG0750	zinc metalloprotease
BKM79_RS05295	COG0360	Binds together with S18 to 16S ribosomal RNA
BKM79_RS05300	COG0629	single-stranded DNA binding
BKM79_RS05310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BKM79_RS05320	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BKM79_RS05325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BKM79_RS05370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BKM79_RS05380	COG0739	heme binding
BKM79_RS05410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKM79_RS05415	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKM79_RS05420	COG1862	Preprotein translocase
BKM79_RS05425	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BKM79_RS05430	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BKM79_RS05435	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BKM79_RS05440	COG0540	Belongs to the ATCase OTCase family
BKM79_RS05470	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BKM79_RS05490	COG0542	response to heat
BKM79_RS05495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BKM79_RS05505	COG2095	MarC family integral membrane protein
BKM79_RS05510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKM79_RS05515	COG2833	Protein of unknown function (DUF455)
BKM79_RS05520	COG1183	phosphatidylcholine synthase activity
BKM79_RS05530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKM79_RS05540	COG0745	RESPONSE REGULATOR receiver
BKM79_RS05555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKM79_RS05565	COG0110	maltose O-acetyltransferase activity
BKM79_RS05570	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BKM79_RS05575	COG0438	transferase activity, transferring glycosyl groups
BKM79_RS05585	COG0438	transferase activity, transferring glycosyl groups
BKM79_RS05590	COG1215	transferase activity, transferring glycosyl groups
BKM79_RS05595	COG0438	transferase activity, transferring glycosyl groups
BKM79_RS05605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKM79_RS05615	COG0859	PFAM glycosyl transferase family 9
BKM79_RS05625	COG0463	Glycosyl transferase, family 2
BKM79_RS05630	COG1442	glycosyl transferase family 8
BKM79_RS05630	COG1216	Glycosyl transferase, family 2
BKM79_RS05640	COG1442	glycosyl transferase family 8
BKM79_RS05640	COG1216	Glycosyl transferase, family 2
BKM79_RS05655	COG2089	acid synthase
BKM79_RS05680	COG1216	Glycosyl transferase, family 2
BKM79_RS05690	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BKM79_RS05695	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BKM79_RS05695	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BKM79_RS05700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKM79_RS05705	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BKM79_RS05720	COG2217	Heavy metal translocating P-type atpase
BKM79_RS05725	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BKM79_RS05760	COG3610	response to peptide
BKM79_RS05775	COG0586	Pfam SNARE associated Golgi protein
BKM79_RS05790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BKM79_RS05795	COG0217	transcriptional regulatory protein
BKM79_RS05820	COG0194	GDP metabolic process
BKM79_RS05830	COG1684	flagellar biosynthetic protein fliR
BKM79_RS05840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BKM79_RS05845	COG0052	Belongs to the universal ribosomal protein uS2 family
BKM79_RS05850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKM79_RS05865	COG0723	plastoquinol--plastocyanin reductase activity
BKM79_RS05870	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BKM79_RS05875	COG0445	tRNA wobble uridine modification
BKM79_RS05895	COG1301	dicarboxylic acid transport
BKM79_RS05910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKM79_RS05920	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKM79_RS05925	COG1854	S-ribosylhomocysteine lyase activity
BKM79_RS05940	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKM79_RS05945	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BKM79_RS05960	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BKM79_RS05965	COG0552	protein localization to endoplasmic reticulum
BKM79_RS05980	COG1418	mRNA catabolic process
BKM79_RS05995	COG1295	ribonuclease BN
BKM79_RS06000	COG0277	FAD linked oxidase domain protein
BKM79_RS06010	COG0739	heme binding
BKM79_RS06020	COG1496	oxidoreductase activity
BKM79_RS06035	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKM79_RS06040	COG0459	protein refolding
BKM79_RS06050	COG0745	RESPONSE REGULATOR receiver
BKM79_RS06075	COG0745	RESPONSE REGULATOR receiver
BKM79_RS06080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKM79_RS06085	COG0484	heat shock protein binding
BKM79_RS06090	COG0789	Transcriptional regulator
BKM79_RS06095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BKM79_RS06095	COG0475	glutathione-regulated potassium exporter activity
BKM79_RS06105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKM79_RS06125	COG0248	Ppx GppA phosphatase
BKM79_RS06130	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BKM79_RS06145	COG2814	Major facilitator Superfamily
BKM79_RS06155	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BKM79_RS06160	COG0731	radical SAM domain protein
BKM79_RS06180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BKM79_RS06180	COG0519	Catalyzes the synthesis of GMP from XMP
BKM79_RS06205	COG1185	polyribonucleotide nucleotidyltransferase activity
BKM79_RS06215	COG1942	4-Oxalocrotonate Tautomerase
BKM79_RS06230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKM79_RS06235	COG4773	Receptor
BKM79_RS06240	COG0484	heat shock protein binding
BKM79_RS06245	COG0745	RESPONSE REGULATOR receiver
BKM79_RS06255	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BKM79_RS06260	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BKM79_RS06265	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
BKM79_RS06270	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BKM79_RS06275	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BKM79_RS06295	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BKM79_RS06300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKM79_RS06305	COG1758	RNA polymerase activity
BKM79_RS06310	COG0528	UMP kinase activity
BKM79_RS06325	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKM79_RS06340	COG0564	pseudouridine synthase activity
BKM79_RS06360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BKM79_RS06365	COG0569	domain protein
BKM79_RS06370	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BKM79_RS06380	COG0281	malic enzyme
BKM79_RS06380	COG0280	phosphate acetyltransferase
BKM79_RS06385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKM79_RS06395	COG0439	Biotin carboxylase
BKM79_RS06400	COG0511	ligase activity, forming carbon-carbon bonds
BKM79_RS06405	COG0717	Belongs to the dCTP deaminase family
BKM79_RS06410	COG1086	Polysaccharide biosynthesis protein
BKM79_RS06420	COG4310	Domain of unknown function (DUF2172)
BKM79_RS06455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKM79_RS06500	COG1083	cytidylyl-transferase
BKM79_RS06505	COG3980	spore coat polysaccharide biosynthesis protein
BKM79_RS06510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKM79_RS06515	COG0107	imidazoleglycerol-phosphate synthase activity
BKM79_RS06520	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BKM79_RS06530	COG2089	acid synthase
BKM79_RS06540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKM79_RS06545	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKM79_RS06575	COG2089	acid synthase
BKM79_RS06580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BKM79_RS06585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BKM79_RS06595	COG1083	cytidylyl-transferase
BKM79_RS06600	COG1028	Short-chain dehydrogenase reductase Sdr
BKM79_RS06625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKM79_RS06630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKM79_RS06645	COG2165	general secretion pathway protein
BKM79_RS06650	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BKM79_RS06660	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BKM79_RS06665	COG0575	Belongs to the CDS family
BKM79_RS06675	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BKM79_RS06685	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
BKM79_RS06690	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKM79_RS06695	COG4605	iron ion homeostasis
BKM79_RS06705	COG4607	ABC-type enterochelin transport system periplasmic component
BKM79_RS06720	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BKM79_RS06725	COG3005	denitrification pathway
BKM79_RS06730	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BKM79_RS06745	COG2255	four-way junction helicase activity
BKM79_RS06750	COG0628	permease
BKM79_RS06755	COG0114	fumarate hydratase activity
BKM79_RS06765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKM79_RS06775	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BKM79_RS06780	COG2252	PERMEase
BKM79_RS06790	COG2853	Lipoprotein
BKM79_RS06805	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BKM79_RS06810	COG2814	Major facilitator Superfamily
BKM79_RS06845	COG0716	FMN binding
BKM79_RS06875	COG0251	oxidation-reduction process
BKM79_RS06900	COG1918	ferrous iron import across plasma membrane
BKM79_RS06910	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BKM79_RS06915	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BKM79_RS06920	COG0149	triose-phosphate isomerase activity
BKM79_RS06930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKM79_RS06955	COG1580	Controls the rotational direction of flagella during chemotaxis
BKM79_RS06960	COG0736	holo-[acyl-carrier-protein] synthase activity
BKM79_RS06990	COG0529	Catalyzes the synthesis of activated sulfate
BKM79_RS06995	COG1213	nucleotidyl transferase
BKM79_RS07000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BKM79_RS07010	COG2226	methyltransferase
BKM79_RS07065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKM79_RS07100	COG0517	IMP dehydrogenase activity
BKM79_RS07100	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BKM79_RS07155	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BKM79_RS07190	COG1706	bacterial-type flagellum-dependent cell motility
BKM79_RS07195	COG3951	Flagellar rod assembly protein muramidase FlgJ
BKM79_RS07260	COG0546	phosphoglycolate phosphatase activity
BKM79_RS07270	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BKM79_RS07275	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BKM79_RS07330	COG0745	RESPONSE REGULATOR receiver
BKM79_RS07345	COG0505	Belongs to the CarA family
BKM79_RS07365	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BKM79_RS07380	COG0425	Belongs to the sulfur carrier protein TusA family
BKM79_RS07385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKM79_RS07425	COG0437	4 iron, 4 sulfur cluster binding
BKM79_RS07440	COG3383	formate dehydrogenase (NAD+) activity
BKM79_RS07475	COG0303	'Molybdopterin
BKM79_RS07480	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BKM79_RS07490	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
BKM79_RS07505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BKM79_RS07510	COG0237	dephospho-CoA kinase activity
BKM79_RS07525	COG0783	Belongs to the Dps family
BKM79_RS07530	COG0166	Belongs to the GPI family
BKM79_RS07540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKM79_RS07550	COG4662	Binding-protein-dependent transport system inner membrane component
BKM79_RS07555	COG2998	abc-type tungstate transport system, permease component
BKM79_RS07560	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BKM79_RS07565	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BKM79_RS07570	COG1984	allophanate hydrolase subunit 2
BKM79_RS07580	COG2249	NAD(P)H dehydrogenase (quinone) activity
BKM79_RS07585	COG1733	regulation of RNA biosynthetic process
BKM79_RS07620	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BKM79_RS07630	COG2910	NAD(P)H-binding
BKM79_RS07635	COG1733	regulation of RNA biosynthetic process
BKM79_RS07670	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKM79_RS07675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKM79_RS07685	COG0839	Belongs to the complex I subunit 6 family
BKM79_RS07695	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BKM79_RS07720	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKM79_RS07725	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKM79_RS07730	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKM79_RS07745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKM79_RS07750	COG0601	transmembrane transport
BKM79_RS07770	COG4615	Cyclic peptide transporter
BKM79_RS07780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKM79_RS07785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BKM79_RS07790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BKM79_RS07800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BKM79_RS07805	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BKM79_RS07810	COG0202	RNA polymerase activity
BKM79_RS07815	COG0203	ribosomal protein L17
BKM79_RS07825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BKM79_RS07830	COG0131	Imidazoleglycerol-phosphate dehydratase
BKM79_RS07830	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BKM79_RS07840	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BKM79_RS07855	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BKM79_RS07855	COG0140	phosphoribosyl-ATP diphosphatase activity
BKM79_RS07860	COG2171	N-acyltransferase activity
BKM79_RS07865	COG0489	protein tyrosine kinase activity
BKM79_RS07870	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BKM79_RS07870	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BKM79_RS07875	COG2046	Belongs to the sulfate adenylyltransferase family
BKM79_RS07880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BKM79_RS07890	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BKM79_RS07900	COG4771	TonB-dependent receptor
BKM79_RS07905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKM79_RS07910	COG1120	ATPase activity
BKM79_RS07925	COG0477	Major facilitator Superfamily
BKM79_RS07960	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKM79_RS07960	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKM79_RS07970	COG1760	l-serine dehydratase
BKM79_RS07975	COG0814	amino acid
BKM79_RS07990	COG0811	peptide transport
BKM79_RS07995	COG0848	biopolymer transport protein
BKM79_RS08020	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BKM79_RS08025	COG0571	ribonuclease III activity
BKM79_RS08030	COG0328	RNA-DNA hybrid ribonuclease activity
BKM79_RS08055	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BKM79_RS08060	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BKM79_RS08075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BKM79_RS08080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKM79_RS08105	COG0024	Methionine aminopeptidase
BKM79_RS08110	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BKM79_RS08115	COG0791	NLP P60 protein
BKM79_RS08165	COG1136	(ABC) transporter
BKM79_RS08230	COG0148	phosphopyruvate hydratase activity
BKM79_RS08235	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BKM79_RS08245	COG1987	bacterial-type flagellum assembly
BKM79_RS08250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BKM79_RS08270	COG1218	3'(2'),5'-bisphosphate nucleotidase
BKM79_RS08275	COG0372	Belongs to the citrate synthase family
BKM79_RS08285	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BKM79_RS08290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BKM79_RS08300	COG0201	protein transport
BKM79_RS08305	COG0200	Binds to the 23S rRNA
BKM79_RS08310	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BKM79_RS08320	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BKM79_RS08325	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BKM79_RS08330	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BKM79_RS08335	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BKM79_RS08340	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BKM79_RS08345	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BKM79_RS08350	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BKM79_RS08355	COG0255	Belongs to the universal ribosomal protein uL29 family
BKM79_RS08360	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BKM79_RS08365	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BKM79_RS08375	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BKM79_RS08385	COG0089	rRNA binding
BKM79_RS08390	COG0088	Forms part of the polypeptide exit tunnel
BKM79_RS08395	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BKM79_RS08400	COG0051	transcription antitermination factor activity, RNA binding
BKM79_RS08405	COG1187	pseudouridine synthase activity
BKM79_RS08410	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BKM79_RS08415	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BKM79_RS08425	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BKM79_RS08495	COG1749	Flagellar hook protein flgE