locus-tag	class	description
AEI20_RS00035	COG2814	Major facilitator Superfamily
AEI20_RS00055	COG1217	gtp-binding protein TYPA
AEI20_RS00070	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AEI20_RS00100	COG0471	metal ion transport
AEI20_RS00110	COG0471	metal ion transport
AEI20_RS00115	COG0471	metal ion transport
AEI20_RS00150	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AEI20_RS00150	COG1776	CheC inhibitor of MCP methylation
AEI20_RS00155	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AEI20_RS00160	COG1191	sigma factor activity
AEI20_RS00170	COG0455	bacterial-type flagellum organization
AEI20_RS00175	COG1419	protein localization to endoplasmic reticulum
AEI20_RS00180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AEI20_RS00185	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AEI20_RS00190	COG0402	S-adenosylhomocysteine deaminase activity
AEI20_RS00195	COG0616	signal peptide processing
AEI20_RS00215	COG1139	Iron-sulfur cluster binding protein
AEI20_RS00220	COG0247	lactate metabolic process
AEI20_RS00235	COG3021	interspecies interaction between organisms
AEI20_RS00250	COG1271	oxidase subunit
AEI20_RS00255	COG1294	oxidase, subunit
AEI20_RS00260	COG1794	racemase activity, acting on amino acids and derivatives
AEI20_RS00270	COG1027	Aspartate ammonia-lyase
AEI20_RS00275	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AEI20_RS00305	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AEI20_RS00310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AEI20_RS00330	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AEI20_RS00330	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AEI20_RS00335	COG1192	Involved in chromosome partitioning
AEI20_RS00340	COG1475	DNA binding
AEI20_RS00355	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AEI20_RS00370	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AEI20_RS00375	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AEI20_RS00380	COG0811	peptide transport
AEI20_RS00385	COG0848	biopolymer transport protein
AEI20_RS00400	COG2885	chlorophyll binding
AEI20_RS00410	COG1047	Peptidyl-prolyl cis-trans
AEI20_RS00415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AEI20_RS00420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AEI20_RS00425	COG0037	tRNA processing
AEI20_RS00450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AEI20_RS00460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AEI20_RS00470	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AEI20_RS00480	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEI20_RS00495	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AEI20_RS00505	COG0083	homoserine kinase activity
AEI20_RS00525	COG0779	Required for maturation of 30S ribosomal subunits
AEI20_RS00530	COG1401	restriction endodeoxyribonuclease activity
AEI20_RS00540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AEI20_RS00545	COG1121	(ABC) transporter
AEI20_RS00565	COG0492	ferredoxin-NADP+ reductase activity
AEI20_RS00570	COG3118	belongs to the thioredoxin family
AEI20_RS00575	COG0792	nuclease activity
AEI20_RS00580	COG0460	homoserine dehydrogenase
AEI20_RS00585	COG0436	Aminotransferase
AEI20_RS00600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AEI20_RS00605	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AEI20_RS00610	COG0254	rRNA binding
AEI20_RS00615	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AEI20_RS00635	COG0602	queuosine metabolic process
AEI20_RS00640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AEI20_RS00665	COG1971	Probably functions as a manganese efflux pump
AEI20_RS00680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AEI20_RS00710	COG1840	ABC-type Fe3 transport system, periplasmic component
AEI20_RS00725	COG1629	transport
AEI20_RS00725	COG4206	TonB-dependent receptor
AEI20_RS00730	COG0811	peptide transport
AEI20_RS00735	COG0848	biopolymer transport protein
AEI20_RS00745	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AEI20_RS00750	COG1253	flavin adenine dinucleotide binding
AEI20_RS00760	COG2824	Alkylphosphonate utilization operon protein PhnA
AEI20_RS00765	COG0861	Integral membrane protein TerC family
AEI20_RS00770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AEI20_RS00775	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AEI20_RS00775	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AEI20_RS00785	COG0606	chelatase, subunit chli
AEI20_RS00790	COG0242	peptide deformylase activity
AEI20_RS00800	COG0544	peptidyl-prolyl cis-trans isomerase activity
AEI20_RS00810	COG1157	protein secretion by the type III secretion system
AEI20_RS00815	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AEI20_RS00820	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AEI20_RS00825	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AEI20_RS00825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AEI20_RS00850	COG2851	Citrate transporter
AEI20_RS00855	COG1297	OPT oligopeptide transporter protein
AEI20_RS00860	COG1968	undecaprenyl-diphosphatase activity
AEI20_RS00865	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AEI20_RS00870	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AEI20_RS00920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AEI20_RS00925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AEI20_RS00930	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AEI20_RS00945	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AEI20_RS00965	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AEI20_RS00970	COG0670	Belongs to the BI1 family
AEI20_RS00975	COG0288	reversible hydration of carbon dioxide
AEI20_RS00980	COG0668	transmembrane transport
AEI20_RS01005	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AEI20_RS01010	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AEI20_RS01035	COG0477	Major facilitator Superfamily
AEI20_RS01045	COG0315	cyclic pyranopterin monophosphate synthase activity
AEI20_RS01050	COG2921	Belongs to the UPF0250 family
AEI20_RS01060	COG0708	Exodeoxyribonuclease III
AEI20_RS01065	COG2194	sulfuric ester hydrolase activity
AEI20_RS01070	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AEI20_RS01080	COG0418	dihydroorotase activity
AEI20_RS01090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AEI20_RS01450	COG0330	HflC and HflK could
AEI20_RS01460	COG1942	4-Oxalocrotonate Tautomerase
AEI20_RS01465	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AEI20_RS01470	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AEI20_RS01475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AEI20_RS01485	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AEI20_RS01490	COG1077	Cell shape determining protein MreB Mrl
AEI20_RS01500	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AEI20_RS01520	COG0835	chemotaxis
AEI20_RS01525	COG2198	Histidine kinase
AEI20_RS01525	COG0784	Response regulator, receiver
AEI20_RS01525	COG0643	Histidine kinase
AEI20_RS01530	COG0835	chemotaxis
AEI20_RS01530	COG0784	Response regulator, receiver
AEI20_RS01545	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AEI20_RS01550	COG0515	serine threonine protein kinase
AEI20_RS01550	COG2815	serine threonine protein kinase
AEI20_RS01595	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AEI20_RS01610	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AEI20_RS01645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AEI20_RS01650	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AEI20_RS01655	COG2076	Multidrug Resistance protein
AEI20_RS01680	COG0019	diaminopimelate decarboxylase activity
AEI20_RS01695	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AEI20_RS01705	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AEI20_RS01715	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AEI20_RS01730	COG2226	methyltransferase
AEI20_RS01735	COG1570	exodeoxyribonuclease VII activity
AEI20_RS01740	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AEI20_RS01745	COG0251	oxidation-reduction process
AEI20_RS01760	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AEI20_RS01780	COG0450	alkyl hydroperoxide reductase
AEI20_RS01785	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AEI20_RS01790	COG1360	Flagellar Motor Protein
AEI20_RS01795	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AEI20_RS01820	COG1238	metal cluster binding
AEI20_RS01825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AEI20_RS01830	COG0730	response to heat
AEI20_RS01845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AEI20_RS01845	COG0512	Glutamine amidotransferase of anthranilate synthase
AEI20_RS01855	COG0133	tryptophan synthase activity
AEI20_RS01870	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AEI20_RS01870	COG1776	CheC inhibitor of MCP methylation
AEI20_RS01885	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AEI20_RS01890	COG0745	RESPONSE REGULATOR receiver
AEI20_RS01910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AEI20_RS01915	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AEI20_RS01920	COG1981	membrane
AEI20_RS01925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEI20_RS01935	COG1538	Outer membrane efflux protein
AEI20_RS01945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEI20_RS01960	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AEI20_RS01975	COG0754	glutathionylspermidine amidase activity
AEI20_RS01980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AEI20_RS02000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AEI20_RS02005	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AEI20_RS02010	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AEI20_RS02030	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AEI20_RS02060	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AEI20_RS02080	COG0579	oxidoreductase
AEI20_RS02085	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AEI20_RS02120	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AEI20_RS02140	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AEI20_RS02160	COG1053	succinate dehydrogenase
AEI20_RS02165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AEI20_RS02175	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AEI20_RS02210	COG2353	YceI-like domain
AEI20_RS02240	COG0488	(ABC) transporter
AEI20_RS02255	COG1739	Uncharacterized protein family UPF0029
AEI20_RS02285	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEI20_RS02290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AEI20_RS02300	COG0839	Belongs to the complex I subunit 6 family
AEI20_RS02310	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AEI20_RS02335	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEI20_RS02345	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEI20_RS02360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AEI20_RS02375	COG0277	FAD linked oxidase domain protein
AEI20_RS02385	COG4615	Cyclic peptide transporter
AEI20_RS02400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AEI20_RS02405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AEI20_RS02415	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AEI20_RS02425	COG0202	RNA polymerase activity
AEI20_RS02430	COG0203	ribosomal protein L17
AEI20_RS02445	COG0131	Imidazoleglycerol-phosphate dehydratase
AEI20_RS02445	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AEI20_RS02455	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AEI20_RS02470	COG0140	phosphoribosyl-ATP diphosphatase activity
AEI20_RS02470	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AEI20_RS02475	COG2171	N-acyltransferase activity
AEI20_RS02480	COG0489	protein tyrosine kinase activity
AEI20_RS02485	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AEI20_RS02485	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AEI20_RS02495	COG2046	Belongs to the sulfate adenylyltransferase family
AEI20_RS02500	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AEI20_RS02505	COG0268	Binds directly to 16S ribosomal RNA
AEI20_RS02515	COG0748	coenzyme F420 binding
AEI20_RS02520	COG4771	TonB-dependent receptor
AEI20_RS02525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AEI20_RS02530	COG1120	ATPase activity
AEI20_RS02535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AEI20_RS02545	COG0477	Major facilitator Superfamily
AEI20_RS02550	COG1194	a g-specific adenine glycosylase
AEI20_RS02580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AEI20_RS02580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AEI20_RS02590	COG1760	l-serine dehydratase
AEI20_RS02595	COG0814	amino acid
AEI20_RS02610	COG0811	peptide transport
AEI20_RS02615	COG0848	biopolymer transport protein
AEI20_RS02640	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AEI20_RS02645	COG0571	ribonuclease III activity
AEI20_RS02650	COG0328	RNA-DNA hybrid ribonuclease activity
AEI20_RS02660	COG0358	DNA primase activity
AEI20_RS02675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AEI20_RS02680	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AEI20_RS02695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AEI20_RS02700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AEI20_RS02705	COG1127	ABC transporter
AEI20_RS02715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AEI20_RS02715	COG3218	ABC-type transport auxiliary lipoprotein component
AEI20_RS02725	COG0024	Methionine aminopeptidase
AEI20_RS02730	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AEI20_RS02735	COG0791	NLP P60 protein
AEI20_RS02745	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AEI20_RS02760	COG0672	)-iron permease
AEI20_RS02785	COG1136	(ABC) transporter
AEI20_RS02835	COG1793	dna ligase
AEI20_RS02850	COG0148	phosphopyruvate hydratase activity
AEI20_RS02855	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AEI20_RS02860	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AEI20_RS02865	COG1987	bacterial-type flagellum assembly
AEI20_RS02880	COG1218	3'(2'),5'-bisphosphate nucleotidase
AEI20_RS02885	COG0372	Belongs to the citrate synthase family
AEI20_RS02895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AEI20_RS02900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AEI20_RS02910	COG0201	protein transport
AEI20_RS02915	COG0200	Binds to the 23S rRNA
AEI20_RS02920	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AEI20_RS02925	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AEI20_RS02930	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AEI20_RS02935	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AEI20_RS02940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AEI20_RS02945	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AEI20_RS02950	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AEI20_RS02955	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AEI20_RS02960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AEI20_RS02965	COG0255	Belongs to the universal ribosomal protein uL29 family
AEI20_RS02970	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AEI20_RS02975	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AEI20_RS02985	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AEI20_RS02995	COG0089	rRNA binding
AEI20_RS03005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AEI20_RS03010	COG0051	transcription antitermination factor activity, RNA binding
AEI20_RS03015	COG1187	pseudouridine synthase activity
AEI20_RS03020	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AEI20_RS03075	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AEI20_RS03100	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AEI20_RS03105	COG1749	Flagellar hook protein flgE
AEI20_RS03120	COG0592	DNA-directed DNA polymerase activity
AEI20_RS03125	COG0187	DNA topoisomerase II activity
AEI20_RS03140	COG2056	Na+-H+ antiporter family
AEI20_RS03145	COG0070	glutamate synthase
AEI20_RS03145	COG0069	glutamate synthase activity
AEI20_RS03145	COG0067	glutamate synthase
AEI20_RS03155	COG0493	'glutamate synthase
AEI20_RS03160	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AEI20_RS03170	COG1592	Rubrerythrin
AEI20_RS03175	COG0129	dihydroxy-acid dehydratase activity
AEI20_RS03190	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AEI20_RS03205	COG0840	transmembrane signaling receptor activity
AEI20_RS03210	COG1858	cytochrome C peroxidase
AEI20_RS03215	COG0179	Fumarylacetoacetate (FAA) hydrolase
AEI20_RS03220	COG0564	pseudouridine synthase activity
AEI20_RS03225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AEI20_RS03230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AEI20_RS03245	COG0504	CTP synthase activity
AEI20_RS03255	COG0252	asparaginase activity
AEI20_RS03290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AEI20_RS03310	COG1028	Short-chain dehydrogenase reductase Sdr
AEI20_RS03320	COG1053	succinate dehydrogenase
AEI20_RS03325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AEI20_RS03330	COG2048	Heterodisulfide reductase, subunit B
AEI20_RS03335	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AEI20_RS03340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AEI20_RS03345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AEI20_RS03375	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AEI20_RS03380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AEI20_RS03390	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AEI20_RS03410	COG2121	Domain of unknown function (DUF374)
AEI20_RS03425	COG0195	Participates in both transcription termination and antitermination
AEI20_RS03435	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AEI20_RS03440	COG0612	Peptidase, M16
AEI20_RS03445	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AEI20_RS03450	COG2346	COG2346, Truncated hemoglobins
AEI20_RS03465	COG0765	amino acid transport
AEI20_RS03495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AEI20_RS03500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AEI20_RS03515	COG0250	Participates in transcription elongation, termination and antitermination
AEI20_RS03520	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AEI20_RS03525	COG0081	regulation of translation
AEI20_RS03535	COG0222	ribosome binding
AEI20_RS03550	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AEI20_RS03555	COG0049	tRNA binding
AEI20_RS03600	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AEI20_RS03605	COG0004	ammonium transporteR
AEI20_RS03615	COG0673	inositol 2-dehydrogenase activity
AEI20_RS03630	COG0424	maF-like protein
AEI20_RS03640	COG0542	response to heat
AEI20_RS03645	COG1937	Protein conserved in bacteria
AEI20_RS03650	COG0793	Belongs to the peptidase S41A family
AEI20_RS03655	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AEI20_RS03660	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AEI20_RS03665	COG0047	phosphoribosylformylglycinamidine synthase activity
AEI20_RS03675	COG0204	Acyl-transferase
AEI20_RS03680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AEI20_RS03690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AEI20_RS03715	COG1677	Flagellar hook-basal body complex protein FliE
AEI20_RS03720	COG1558	bacterial-type flagellum-dependent cell motility
AEI20_RS03725	COG1815	bacterial-type flagellum-dependent cell motility
AEI20_RS03745	COG0039	L-malate dehydrogenase activity
AEI20_RS03755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AEI20_RS03765	COG0674	pyruvate-flavodoxin oxidoreductase activity
AEI20_RS03765	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AEI20_RS03770	COG1013	pyruvate-flavodoxin oxidoreductase activity
AEI20_RS03790	COG0142	geranyltranstransferase activity
AEI20_RS03795	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AEI20_RS03810	COG0181	hydroxymethylbilane synthase activity
AEI20_RS03815	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AEI20_RS03825	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AEI20_RS03845	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AEI20_RS03875	COG1289	transmembrane transporter activity
AEI20_RS03880	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AEI20_RS03885	COG0492	ferredoxin-NADP+ reductase activity
AEI20_RS03900	COG0305	Participates in initiation and elongation during chromosome replication
AEI20_RS03915	COG1162	GTPase activity
AEI20_RS03950	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEI20_RS03950	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEI20_RS03955	COG1610	YqeY-like protein
AEI20_RS03960	COG0028	Belongs to the TPP enzyme family
AEI20_RS03965	COG0440	acetolactate synthase activity
AEI20_RS03980	COG0805	protein transport
AEI20_RS03990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEI20_RS03995	COG0494	nUDIX hydrolase
AEI20_RS04000	COG0527	aspartate kinase activity
AEI20_RS04015	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AEI20_RS04020	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AEI20_RS04035	COG0196	riboflavin kinase activity
AEI20_RS04040	COG2890	protein-(glutamine-N5) methyltransferase activity
AEI20_RS04055	COG2860	membrane
AEI20_RS04065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AEI20_RS04070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AEI20_RS04075	COG0191	fructose-bisphosphate aldolase activity
AEI20_RS04095	COG0733	neurotransmitter:sodium symporter activity
AEI20_RS04100	COG2258	MOSC domain
AEI20_RS04115	COG1473	amidohydrolase
AEI20_RS04120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEI20_RS04125	COG0577	efflux transmembrane transporter activity
AEI20_RS04125	COG1136	(ABC) transporter
AEI20_RS04130	COG1538	Outer membrane efflux protein
AEI20_RS04145	COG1696	Membrane protein involved in D-alanine export
AEI20_RS04150	COG1528	Iron-storage protein
AEI20_RS04155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AEI20_RS04160	COG0573	inorganic phosphate transmembrane transporter activity
AEI20_RS04165	COG0581	inorganic phosphate transmembrane transporter activity
AEI20_RS04180	COG0534	Mate efflux family protein
AEI20_RS04195	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AEI20_RS04205	COG0298	carbon dioxide binding
AEI20_RS04210	COG0409	Hydrogenase expression formation protein
AEI20_RS04215	COG0309	Hydrogenase expression formation protein (HypE)
AEI20_RS04220	COG0375	protein maturation
AEI20_RS04225	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AEI20_RS04230	COG3421	Type III restriction
AEI20_RS04240	COG0557	exoribonuclease II activity
AEI20_RS04245	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AEI20_RS04255	COG0758	DNA mediated transformation
AEI20_RS04275	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AEI20_RS04285	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AEI20_RS04295	COG0497	DNA recombination
AEI20_RS04305	COG0084	hydrolase, TatD family'
AEI20_RS04310	COG0791	NLP P60 protein
AEI20_RS04310	COG1388	LysM domain
AEI20_RS04315	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AEI20_RS04380	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AEI20_RS04385	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AEI20_RS04400	COG0137	argininosuccinate synthase activity
AEI20_RS04405	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AEI20_RS04410	COG0802	atpase or kinase
AEI20_RS04415	COG1137	ATPase activity
AEI20_RS04420	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AEI20_RS04445	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AEI20_RS04475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AEI20_RS04485	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AEI20_RS04495	COG0280	phosphate acetyltransferase
AEI20_RS04530	COG0849	cell division
AEI20_RS04535	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AEI20_RS04540	COG4786	Flagellar basal body rod
AEI20_RS04545	COG4786	Flagellar basal body rod
AEI20_RS04550	COG0174	glutamine synthetase
AEI20_RS04560	COG0826	peptidase U32
AEI20_RS04565	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AEI20_RS04575	COG0752	glycyl-tRNA synthetase alpha subunit
AEI20_RS04580	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AEI20_RS04590	COG1519	Transferase
AEI20_RS04590	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AEI20_RS04595	COG0564	pseudouridine synthase activity
AEI20_RS04600	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AEI20_RS04605	COG0228	four-way junction DNA binding
AEI20_RS04610	COG1837	Belongs to the UPF0109 family
AEI20_RS04615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AEI20_RS04635	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AEI20_RS04640	COG1393	Belongs to the ArsC family
AEI20_RS04650	COG0587	DNA-directed DNA polymerase activity
AEI20_RS04655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AEI20_RS04670	COG2890	protein-(glutamine-N5) methyltransferase activity
AEI20_RS04675	COG0501	Belongs to the peptidase M48B family
AEI20_RS04685	COG0521	Mo-molybdopterin cofactor biosynthetic process
AEI20_RS04690	COG0598	Magnesium transport protein CorA
AEI20_RS04710	COG1178	ABC-type Fe3 transport system permease component
AEI20_RS04720	COG3842	ATPase activity
AEI20_RS04775	COG0675	Transposase, IS605 OrfB family
AEI20_RS04785	COG4771	TonB-dependent receptor
AEI20_RS04790	COG1420	regulation of RNA biosynthetic process
AEI20_RS04795	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AEI20_RS04815	COG0436	Aminotransferase
AEI20_RS04820	COG1045	serine acetyltransferase
AEI20_RS04825	COG1166	arginine decarboxylase activity
AEI20_RS04840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AEI20_RS04845	COG0163	prenyltransferase activity
AEI20_RS04855	COG1464	Belongs to the NlpA lipoprotein family
AEI20_RS04860	COG1464	Belongs to the NlpA lipoprotein family
AEI20_RS04865	COG1464	Belongs to the NlpA lipoprotein family
AEI20_RS04870	COG2011	ABC-type metal ion transport system permease component
AEI20_RS04875	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AEI20_RS04890	COG0210	DNA helicase
AEI20_RS04900	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AEI20_RS04910	COG0437	4 iron, 4 sulfur cluster binding
AEI20_RS04915	COG0348	domain, Protein
AEI20_RS04920	COG3043	anaerobic respiration
AEI20_RS04955	COG0788	formyltetrahydrofolate deformylase activity
AEI20_RS04960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AEI20_RS04970	COG0642	Histidine kinase
AEI20_RS04985	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AEI20_RS05000	COG1181	Belongs to the D-alanine--D-alanine ligase family
AEI20_RS05005	COG0632	four-way junction helicase activity
AEI20_RS05015	COG0728	peptidoglycan biosynthetic process
AEI20_RS05020	COG0215	cysteine-tRNA ligase activity
AEI20_RS05025	COG1132	(ABC) transporter
AEI20_RS05030	COG0167	dihydroorotate dehydrogenase activity
AEI20_RS05035	COG0612	Peptidase, M16
AEI20_RS05040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AEI20_RS05045	COG1028	Short-chain dehydrogenase reductase Sdr
AEI20_RS05060	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AEI20_RS05070	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AEI20_RS05075	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AEI20_RS05090	COG1338	Plays a role in the flagellum-specific transport system
AEI20_RS05095	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AEI20_RS05125	COG0101	tRNA pseudouridine synthase activity
AEI20_RS05130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AEI20_RS05150	COG1757	Na H antiporter
AEI20_RS05155	COG4221	oxidoreductase activity
AEI20_RS05165	COG1049	propionate catabolic process, 2-methylcitrate cycle
AEI20_RS05170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AEI20_RS05180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEI20_RS05180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEI20_RS05190	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AEI20_RS05220	COG1408	metallophosphoesterase
AEI20_RS05225	COG0688	phosphatidylethanolamine metabolic process
AEI20_RS05270	COG0681	Belongs to the peptidase S26 family
AEI20_RS05275	COG0303	'Molybdopterin
AEI20_RS05290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AEI20_RS05290	COG0512	Glutamine amidotransferase of anthranilate synthase
AEI20_RS05295	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AEI20_RS05300	COG0582	viral genome integration into host DNA
AEI20_RS05305	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AEI20_RS05310	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AEI20_RS05325	COG3258	Cytochrome c
AEI20_RS05350	COG2404	hydrolase activity, acting on ester bonds
AEI20_RS05355	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AEI20_RS05360	COG1959	2 iron, 2 sulfur cluster binding
AEI20_RS05365	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AEI20_RS05370	COG1674	ftsk spoiiie
AEI20_RS05370	COG1196	nuclear chromosome segregation
AEI20_RS05375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AEI20_RS05390	COG0488	(ABC) transporter
AEI20_RS05395	COG5002	protein histidine kinase activity
AEI20_RS05400	COG0745	RESPONSE REGULATOR receiver
AEI20_RS05405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AEI20_RS05415	COG1185	polyribonucleotide nucleotidyltransferase activity
AEI20_RS05415	COG0539	negative regulation of cytoplasmic translation
AEI20_RS05420	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AEI20_RS05425	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AEI20_RS05430	COG0072	phenylalanine-tRNA ligase activity
AEI20_RS05430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEI20_RS05435	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AEI20_RS05440	COG0537	adenosine 5'-monophosphoramidase activity
AEI20_RS05455	COG0765	amino acid transport
AEI20_RS05465	COG1115	amino acid carrier protein
AEI20_RS05475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AEI20_RS05500	COG1999	signal sequence binding
AEI20_RS05505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AEI20_RS05510	COG0776	regulation of translation
AEI20_RS05530	COG1966	Carbon starvation protein
AEI20_RS05535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AEI20_RS05540	COG0765	amino acid transport
AEI20_RS05545	COG0765	amino acid transport
AEI20_RS05550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AEI20_RS05555	COG1126	abc transporter atp-binding protein
AEI20_RS05560	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AEI20_RS05565	COG2201	protein-glutamate methylesterase activity
AEI20_RS05590	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AEI20_RS05595	COG0012	GTP binding
AEI20_RS05605	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AEI20_RS05610	COG0511	ligase activity, forming carbon-carbon bonds
AEI20_RS05610	COG5016	pyruvate
AEI20_RS05615	COG0733	neurotransmitter:sodium symporter activity
AEI20_RS05620	COG0733	neurotransmitter:sodium symporter activity
AEI20_RS05685	COG0765	amino acid transport
AEI20_RS05695	COG0653	protein targeting
AEI20_RS05700	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AEI20_RS05710	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AEI20_RS05725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AEI20_RS05745	COG0840	transmembrane signaling receptor activity
AEI20_RS05755	COG0138	bifunctional purine biosynthesis protein purh
AEI20_RS05760	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AEI20_RS05770	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AEI20_RS05780	COG0706	membrane insertase activity
AEI20_RS05795	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AEI20_RS05860	COG2195	Cleaves the N-terminal amino acid of tripeptides
AEI20_RS05865	COG0477	Major facilitator Superfamily
AEI20_RS05870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AEI20_RS05880	COG3022	response to hydroperoxide
AEI20_RS05885	COG1473	amidohydrolase
AEI20_RS05890	COG2807	transmembrane transport
AEI20_RS05910	COG0247	lactate metabolic process
AEI20_RS05910	COG2181	nitrate reductase activity
AEI20_RS05915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEI20_RS05925	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AEI20_RS05930	COG0113	porphobilinogen synthase activity
AEI20_RS05935	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEI20_RS05940	COG0357	Ribosomal RNA small subunit methyltransferase G
AEI20_RS05950	COG2855	membrane
AEI20_RS05955	COG0583	DNA-binding transcription factor activity
AEI20_RS05960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AEI20_RS05980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AEI20_RS05985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEI20_RS06290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AEI20_RS06290	COG1333	cytochrome c biogenesis protein
AEI20_RS06340	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AEI20_RS06345	COG2204	response regulator
AEI20_RS06360	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AEI20_RS06375	COG0481	GTPase activity
AEI20_RS06400	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AEI20_RS06410	COG0439	Biotin carboxylase
AEI20_RS06415	COG0772	Belongs to the SEDS family
AEI20_RS06420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AEI20_RS06445	COG0352	thiamine-phosphate diphosphorylase activity
AEI20_RS06450	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AEI20_RS06455	COG2022	thiamine diphosphate biosynthetic process
AEI20_RS06470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AEI20_RS06490	COG1193	negative regulation of DNA recombination
AEI20_RS06520	COG0517	IMP dehydrogenase activity
AEI20_RS06520	COG0516	GMP reductase activity
AEI20_RS06540	COG1058	Belongs to the CinA family
AEI20_RS06540	COG1546	Belongs to the CinA family
AEI20_RS06550	COG0778	Nitroreductase
AEI20_RS06555	COG0778	Nitroreductase
AEI20_RS06565	COG0750	zinc metalloprotease
AEI20_RS06570	COG2990	Protein conserved in bacteria
AEI20_RS06580	COG0629	single-stranded DNA binding
AEI20_RS06585	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AEI20_RS06590	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AEI20_RS06600	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AEI20_RS06605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AEI20_RS06650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AEI20_RS06660	COG0739	heme binding
AEI20_RS06665	COG0285	dihydrofolate synthase activity
AEI20_RS06685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AEI20_RS06690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AEI20_RS06695	COG1862	Preprotein translocase
AEI20_RS06700	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AEI20_RS06705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AEI20_RS06710	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AEI20_RS06715	COG0540	Belongs to the ATCase OTCase family
AEI20_RS06730	COG0210	DNA helicase
AEI20_RS06765	COG0542	response to heat
AEI20_RS06770	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AEI20_RS06780	COG2095	MarC family integral membrane protein
AEI20_RS06785	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEI20_RS06790	COG2833	Protein of unknown function (DUF455)
AEI20_RS06795	COG1183	phosphatidylcholine synthase activity
AEI20_RS06805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AEI20_RS06815	COG0745	RESPONSE REGULATOR receiver
AEI20_RS06825	COG1086	Polysaccharide biosynthesis protein
AEI20_RS06830	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AEI20_RS06835	COG0110	maltose O-acetyltransferase activity
AEI20_RS06840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AEI20_RS06845	COG0438	transferase activity, transferring glycosyl groups
AEI20_RS06855	COG0438	transferase activity, transferring glycosyl groups
AEI20_RS06860	COG1215	transferase activity, transferring glycosyl groups
AEI20_RS06865	COG0438	transferase activity, transferring glycosyl groups
AEI20_RS06870	COG1132	(ABC) transporter
AEI20_RS06875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AEI20_RS06885	COG0859	PFAM glycosyl transferase family 9
AEI20_RS06890	COG1560	Kdo2-lipid A biosynthetic process
AEI20_RS06900	COG1442	glycosyl transferase family 8
AEI20_RS06900	COG1216	Glycosyl transferase, family 2
AEI20_RS06910	COG1442	glycosyl transferase family 8
AEI20_RS06910	COG1216	Glycosyl transferase, family 2
AEI20_RS06920	COG2089	acid synthase
AEI20_RS06940	COG0110	maltose O-acetyltransferase activity
AEI20_RS06945	COG1216	Glycosyl transferase, family 2
AEI20_RS06965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEI20_RS06970	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AEI20_RS06985	COG2217	Heavy metal translocating P-type atpase
AEI20_RS06990	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AEI20_RS06995	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AEI20_RS07015	COG2217	Heavy metal translocating P-type atpase
AEI20_RS07035	COG3610	response to peptide
AEI20_RS07045	COG0039	L-malate dehydrogenase activity
AEI20_RS07050	COG0586	Pfam SNARE associated Golgi protein
AEI20_RS07065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AEI20_RS07070	COG0217	transcriptional regulatory protein
AEI20_RS07090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEI20_RS07095	COG0194	GDP metabolic process
AEI20_RS07105	COG1684	flagellar biosynthetic protein fliR
AEI20_RS07115	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AEI20_RS07120	COG0052	Belongs to the universal ribosomal protein uS2 family
AEI20_RS07125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AEI20_RS07135	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AEI20_RS07140	COG0723	plastoquinol--plastocyanin reductase activity
AEI20_RS07145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AEI20_RS07150	COG0445	tRNA wobble uridine modification
AEI20_RS07170	COG1301	dicarboxylic acid transport
AEI20_RS07185	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AEI20_RS07200	COG1854	S-ribosylhomocysteine lyase activity
AEI20_RS07220	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AEI20_RS07235	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AEI20_RS07240	COG0552	protein localization to endoplasmic reticulum
AEI20_RS07255	COG1418	mRNA catabolic process
AEI20_RS07270	COG1295	ribonuclease BN
AEI20_RS07275	COG0277	FAD linked oxidase domain protein
AEI20_RS07285	COG0739	heme binding
AEI20_RS07295	COG1496	oxidoreductase activity
AEI20_RS07310	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AEI20_RS07315	COG0459	protein refolding
AEI20_RS07320	COG0642	Histidine kinase
AEI20_RS07325	COG0745	RESPONSE REGULATOR receiver
AEI20_RS07345	COG0642	Histidine kinase
AEI20_RS07350	COG0745	RESPONSE REGULATOR receiver
AEI20_RS07355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AEI20_RS07360	COG0484	heat shock protein binding
AEI20_RS07365	COG0789	Transcriptional regulator
AEI20_RS07370	COG0475	glutathione-regulated potassium exporter activity
AEI20_RS07370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AEI20_RS07380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AEI20_RS07385	COG0751	glycine-tRNA ligase activity
AEI20_RS07390	COG0739	heme binding
AEI20_RS07400	COG0248	Ppx GppA phosphatase
AEI20_RS07420	COG2814	Major facilitator Superfamily
AEI20_RS07435	COG0731	radical SAM domain protein
AEI20_RS07455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AEI20_RS07455	COG0519	Catalyzes the synthesis of GMP from XMP
AEI20_RS07480	COG1185	polyribonucleotide nucleotidyltransferase activity
AEI20_RS07495	COG2814	Major facilitator Superfamily
AEI20_RS07500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AEI20_RS07505	COG4773	Receptor
AEI20_RS07510	COG0484	heat shock protein binding
AEI20_RS07515	COG0745	RESPONSE REGULATOR receiver
AEI20_RS07520	COG0642	Histidine kinase
AEI20_RS07525	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AEI20_RS07530	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AEI20_RS07535	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AEI20_RS07540	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AEI20_RS07545	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AEI20_RS07570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AEI20_RS07575	COG1758	RNA polymerase activity
AEI20_RS07580	COG0528	UMP kinase activity
AEI20_RS07595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AEI20_RS07610	COG0564	pseudouridine synthase activity
AEI20_RS07615	COG0772	Belongs to the SEDS family
AEI20_RS07630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AEI20_RS07635	COG0569	domain protein
AEI20_RS07640	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AEI20_RS07645	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AEI20_RS07650	COG0281	malic enzyme
AEI20_RS07650	COG0280	phosphate acetyltransferase
AEI20_RS07665	COG0439	Biotin carboxylase
AEI20_RS07670	COG0511	ligase activity, forming carbon-carbon bonds
AEI20_RS07680	COG1086	Polysaccharide biosynthesis protein
AEI20_RS07685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AEI20_RS07725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEI20_RS07770	COG1083	cytidylyl-transferase
AEI20_RS07775	COG3980	spore coat polysaccharide biosynthesis protein
AEI20_RS07780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AEI20_RS07785	COG0107	imidazoleglycerol-phosphate synthase activity
AEI20_RS07800	COG2089	acid synthase
AEI20_RS07810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEI20_RS07815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AEI20_RS07825	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AEI20_RS07845	COG2089	acid synthase
AEI20_RS07850	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AEI20_RS07855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AEI20_RS07865	COG1083	cytidylyl-transferase
AEI20_RS07870	COG1028	Short-chain dehydrogenase reductase Sdr
AEI20_RS07915	COG2165	general secretion pathway protein
AEI20_RS07920	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AEI20_RS07935	COG0575	Belongs to the CDS family
AEI20_RS07945	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AEI20_RS07955	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AEI20_RS07960	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AEI20_RS07965	COG4605	iron ion homeostasis
AEI20_RS07970	COG4604	ABC transporter, ATP-binding protein
AEI20_RS07975	COG4607	ABC-type enterochelin transport system periplasmic component
AEI20_RS07990	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AEI20_RS07995	COG3005	denitrification pathway
AEI20_RS08040	COG0628	permease
AEI20_RS08045	COG0114	fumarate hydratase activity
AEI20_RS08055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AEI20_RS08065	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AEI20_RS08070	COG2252	PERMEase
AEI20_RS08080	COG2853	Lipoprotein
AEI20_RS08100	COG2814	Major facilitator Superfamily
AEI20_RS08115	COG3276	selenocysteine insertion sequence binding
AEI20_RS08145	COG0753	catalase activity
AEI20_RS08155	COG2964	Protein conserved in bacteria
AEI20_RS08160	COG0251	oxidation-reduction process
AEI20_RS08185	COG1918	ferrous iron import across plasma membrane
AEI20_RS08190	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AEI20_RS08195	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AEI20_RS08200	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AEI20_RS08215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AEI20_RS08240	COG1580	Controls the rotational direction of flagella during chemotaxis
AEI20_RS08255	COG2124	cytochrome p450
AEI20_RS08275	COG0529	Catalyzes the synthesis of activated sulfate
AEI20_RS08280	COG1213	nucleotidyl transferase
AEI20_RS08285	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AEI20_RS08290	COG0574	Belongs to the PEP-utilizing enzyme family
AEI20_RS08290	COG3848	Pyruvate phosphate dikinase
AEI20_RS08295	COG2226	methyltransferase
AEI20_RS08325	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AEI20_RS08345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEI20_RS08390	COG0562	UDP-galactopyranose mutase
AEI20_RS08395	COG1216	Glycosyl transferase, family 2
AEI20_RS08395	COG1442	glycosyl transferase family 8
AEI20_RS08410	COG0517	IMP dehydrogenase activity
AEI20_RS08410	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AEI20_RS08465	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AEI20_RS08480	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AEI20_RS08500	COG1706	bacterial-type flagellum-dependent cell motility
AEI20_RS08505	COG3951	Flagellar rod assembly protein muramidase FlgJ
AEI20_RS08530	COG0730	response to heat
AEI20_RS08535	COG1459	type II secretion system
AEI20_RS08540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AEI20_RS08570	COG0546	phosphoglycolate phosphatase activity
AEI20_RS08580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AEI20_RS08585	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AEI20_RS08590	COG0210	DNA helicase
AEI20_RS08595	COG2887	Belongs to the helicase family. UvrD subfamily
AEI20_RS08640	COG0745	RESPONSE REGULATOR receiver
AEI20_RS08655	COG0505	Belongs to the CarA family
AEI20_RS08675	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AEI20_RS08690	COG0425	Belongs to the sulfur carrier protein TusA family
AEI20_RS08695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AEI20_RS08725	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AEI20_RS08735	COG0437	4 iron, 4 sulfur cluster binding
AEI20_RS08770	COG0314	molybdopterin synthase activity
AEI20_RS08775	COG0303	'Molybdopterin
AEI20_RS08780	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AEI20_RS08820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AEI20_RS08835	COG2992	FlgJ-related protein
AEI20_RS08845	COG0783	Belongs to the Dps family
AEI20_RS08850	COG0166	Belongs to the GPI family
AEI20_RS08860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AEI20_RS08865	COG3839	Belongs to the ABC transporter superfamily
AEI20_RS08870	COG4662	Binding-protein-dependent transport system inner membrane component
AEI20_RS08875	COG2998	abc-type tungstate transport system, permease component
AEI20_RS08880	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AEI20_RS08885	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AEI20_RS08890	COG1984	allophanate hydrolase subunit 2
AEI20_RS08900	COG2249	NAD(P)H dehydrogenase (quinone) activity
AEI20_RS08905	COG1733	regulation of RNA biosynthetic process
AEI20_RS08915	COG1064	alcohol dehydrogenase
AEI20_RS08930	COG0732	type I restriction modification DNA specificity domain
AEI20_RS08955	COG2814	Major facilitator Superfamily
AEI20_RS08975	COG0640	Transcriptional regulator
AEI20_RS09070	COG1216	Glycosyl transferase, family 2
AEI20_RS09085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily