locus-tag	class	description
FORC46_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FORC46_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FORC46_RS00015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FORC46_RS00030	ENOG4105D3Y	Na H antiporter
FORC46_RS00040	ENOG4105BZ8	glutamate synthase
FORC46_RS00055	ENOG4108RAC	Rubrerythrin
FORC46_RS00060	ENOG4105C01	Dihydroxy-acid dehydratase
FORC46_RS00065	ENOG4105R3P	Inner membrane protein yagU
FORC46_RS00075	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
FORC46_RS00090	ENOG4108N3W	hemolysin secretion protein
FORC46_RS00095	ENOG4105CA0	peroxidase
FORC46_RS00100	ENOG4105ERH	Fumarylacetoacetate hydrolase
FORC46_RS00105	ENOG4105EI2	Pseudouridine synthase
FORC46_RS00110	ENOG4107QTF	adenylosuccinate lyase
FORC46_RS00115	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FORC46_RS00135	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FORC46_RS00140	ENOG4107RB3	L-asparaginase
FORC46_RS00170	ENOG4105V2T	cytochrome C
FORC46_RS00215	ENOG4105C2C	drug resistance transporter, Bcr CflA
FORC46_RS00235	ENOG4105CI3	gtp-binding protein typa
FORC46_RS00250	ENOG410822I	Flagellar hook capping protein
FORC46_RS00255	ENOG4105BZE	flagellar hook protein, FlgE
FORC46_RS00280	ENOG4107QPK	)-transporter
FORC46_RS00290	ENOG4107QPK	)-transporter
FORC46_RS00295	ENOG4107QPK	)-transporter
FORC46_RS00305	ENOG4108URH	decarboxylase
FORC46_RS00340	ENOG4105DD5	Flagellar motor switch protein
FORC46_RS00345	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FORC46_RS00350	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FORC46_RS00360	ENOG4107R21	site-determining protein
FORC46_RS00365	ENOG4105FZW	flagellar biosynthesis regulator FlhF
FORC46_RS00370	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC46_RS00375	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
FORC46_RS00380	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FORC46_RS00385	ENOG4105D07	Signal peptide peptidase, SppA
FORC46_RS00405	ENOG4107QR9	Iron-sulfur cluster binding protein
FORC46_RS00410	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FORC46_RS00415	ENOG4105DAA	L-lactate
FORC46_RS00425	ENOG4108TMH	cytolethal distending toxin
FORC46_RS00430	ENOG4106BMH	cytolethal distending toxin
FORC46_RS00440	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FORC46_RS00445	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FORC46_RS00455	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
FORC46_RS00460	ENOG4108IJ0	Aspartate ammonia-lyase
FORC46_RS00465	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
FORC46_RS00495	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FORC46_RS00500	ENOG4105K46	50S ribosomal protein l27
FORC46_RS00505	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FORC46_RS00520	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
FORC46_RS00525	ENOG4107QJE	Chromosome Partitioning Protein
FORC46_RS00530	ENOG4105FA0	parb-like partition protein
FORC46_RS00540	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
FORC46_RS00545	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FORC46_RS00550	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FORC46_RS00560	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FORC46_RS00565	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FORC46_RS00570	ENOG4105E02	MotA TolQ exbB proton channel
FORC46_RS00575	ENOG4105M8F	Biopolymer transport protein exbD tolR
FORC46_RS00590	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
FORC46_RS00600	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
FORC46_RS00605	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FORC46_RS00610	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
FORC46_RS00615	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
FORC46_RS00630	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FORC46_RS00640	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FORC46_RS00650	ENOG4105SCY	DNAK suppressor
FORC46_RS00660	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FORC46_RS00665	ENOG4105ECY	inositol monophosphatase
FORC46_RS00670	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC46_RS00695	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
FORC46_RS00720	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
FORC46_RS00745	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC46_RS00755	ENOG4105C3M	thioredoxin reductase
FORC46_RS00760	ENOG4105K63	Thioredoxin
FORC46_RS00765	ENOG41082UM	UPF0102 protein
FORC46_RS00770	ENOG4105D6E	homoserine dehydrogenase
FORC46_RS00775	ENOG4105CHM	Aminotransferase
FORC46_RS00790	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FORC46_RS00800	ENOG41082DI	50s ribosomal protein l31
FORC46_RS00805	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
FORC46_RS00825	ENOG4107XWN	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FORC46_RS00830	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FORC46_RS00855	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
FORC46_RS00870	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FORC46_RS00920	ENOG4105CWK	Biopolymer transport protein, ExbB
FORC46_RS00925	ENOG4108ZZF	transport protein (ExbD)
FORC46_RS00935	ENOG4108DQG	in Escherichia coli SbmA is involved in uptake of microcin J25
FORC46_RS00940	ENOG4105C37	(CBS) domain
FORC46_RS00950	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
FORC46_RS00955	ENOG4105EE5	Membrane protein terC
FORC46_RS00960	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FORC46_RS00965	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FORC46_RS00975	ENOG4105C0P	Mg chelatase subunit ChlI
FORC46_RS00980	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FORC46_RS00990	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FORC46_RS00995	ENOG4105EUJ	GTP cyclohydrolase i
FORC46_RS01000	ENOG4108JIR	Flagellum-specific ATP synthase
FORC46_RS01010	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FORC46_RS01015	ENOG4105D1H	recombination factor protein RarA
FORC46_RS01045	ENOG4105EPD	Oligopeptide transporter, Opt family
FORC46_RS01050	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FORC46_RS01115	ENOG4105CAS	nag kinase
FORC46_RS01120	ENOG4105C8Y	Acetylornithine aminotransferase
FORC46_RS01125	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FORC46_RS01140	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FORC46_RS01155	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FORC46_RS01160	ENOG4105NU9	Preprotein translocase subunit SecG
FORC46_RS01165	ENOG4105HFZ	Membrane
FORC46_RS01170	ENOG4107B2H	carbonic anhydrase
FORC46_RS01175	ENOG4105D64	Mechanosensitive ion channel
FORC46_RS01180	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
FORC46_RS01200	ENOG41084M8	50s ribosomal protein L35
FORC46_RS01205	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FORC46_RS01210	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC46_RS01235	ENOG4105CSH	Transporter
FORC46_RS01250	ENOG41068HQ	Protein of unknown function (DUF493)
FORC46_RS01260	ENOG4105CGK	Exodeoxyribonuclease III
FORC46_RS01265	ENOG4105DIJ	Phosphoethanolamine transferase
FORC46_RS01270	ENOG41080IJ	Diacylglycerol kinase
FORC46_RS01280	ENOG4105EKE	dihydroorotase
FORC46_RS01290	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FORC46_RS01295	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC46_RS01300	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
FORC46_RS01305	ENOG4107QY8	reductase
FORC46_RS01325	ENOG4105EPW	hflc protein
FORC46_RS01330	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FORC46_RS01335	ENOG4108F90	4-oxalocrotonate tautomerase
FORC46_RS01340	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC46_RS01345	ENOG4105WPN	DNA integration recombination invertion protein
FORC46_RS01355	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FORC46_RS01360	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FORC46_RS01375	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FORC46_RS01385	ENOG4107V25	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FORC46_RS01415	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FORC46_RS01420	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FORC46_RS01475	ENOG4105E0C	molybdate abc transporter
FORC46_RS01485	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
FORC46_RS01490	ENOG410825B	Type 11 methyltransferase
FORC46_RS01495	ENOG4105HSA	Protein of unknown function (DUF452)
FORC46_RS01500	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FORC46_RS01505	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FORC46_RS01510	ENOG4107S77	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
FORC46_RS01515	ENOG41080TC	multidrug resistance protein
FORC46_RS01530	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FORC46_RS01540	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FORC46_RS01550	ENOG4105CQC	Prephenate dehydratase
FORC46_RS01560	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
FORC46_RS01565	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FORC46_RS01600	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
FORC46_RS01605	ENOG4105M4H	endoribonuclease L-psp
FORC46_RS01610	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FORC46_RS01620	ENOG4105YQ2	50s ribosomal protein l32
FORC46_RS01640	ENOG4105D3R	alkyl hydroperoxide reductase
FORC46_RS01645	ENOG4105D00	flagellar biosynthetic protein flhB
FORC46_RS01650	ENOG4108SEK	ompa motb domain protein
FORC46_RS01655	ENOG4105E14	MotA TolQ exbB proton channel
FORC46_RS01660	ENOG4105C2M	dna polymerase I
FORC46_RS01685	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FORC46_RS01705	ENOG4108EFP	Anthranilate synthase component II
FORC46_RS01715	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FORC46_RS01730	ENOG4105DD5	Flagellar motor switch protein
FORC46_RS01745	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
FORC46_RS01750	ENOG4105ETX	regulatoR
FORC46_RS01760	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FORC46_RS01765	ENOG4105CA0	peroxidase
FORC46_RS01770	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FORC46_RS01775	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FORC46_RS01780	ENOG4108YXA	Membrane
FORC46_RS01785	ENOG4105CSA	Coproporphyrinogen iii oxidase
FORC46_RS01795	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FORC46_RS01805	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FORC46_RS01820	ENOG41082DJ	30S ribosomal protein S21
FORC46_RS01830	ENOG4108UHV	Lipoprotein
FORC46_RS01835	ENOG4106032	Glutathionylspermidine synthase
FORC46_RS01840	ENOG4105C5I	Dehydrogenase
FORC46_RS01845	ENOG4108VPT	UPF0234 protein
FORC46_RS01860	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FORC46_RS01865	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
FORC46_RS01870	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
FORC46_RS01875	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FORC46_RS01885	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
FORC46_RS01890	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FORC46_RS01900	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FORC46_RS01905	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FORC46_RS01930	ENOG4105CA9	Pyruvate kinase
FORC46_RS01935	ENOG4107RSR	Malate quinone oxidoreductase
FORC46_RS01940	ENOG4108VHG	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
FORC46_RS01950	ENOG4108TX7	
FORC46_RS01960	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FORC46_RS01995	ENOG4105E2X	shikimate dehydrogenase
FORC46_RS02010	ENOG4108S24	Fumarate reduCtase
FORC46_RS02015	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
FORC46_RS02020	ENOG4105E33	succinate dehydrogenase
FORC46_RS02080	ENOG4105C5H	ABC transporter
FORC46_RS02095	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
FORC46_RS02135	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FORC46_RS02140	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FORC46_RS02145	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FORC46_RS02155	ENOG4105CHR	reductase
FORC46_RS02165	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
FORC46_RS02170	ENOG4105E33	succinate dehydrogenase
FORC46_RS02175	ENOG41086B8	CoB-CoM heterodisulfide reductase
FORC46_RS02180	ENOG4105ETU	transcriptional activator (TenA
FORC46_RS02185	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FORC46_RS02190	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FORC46_RS02200	ENOG4105D05	Receptor
FORC46_RS02205	ENOG4107VIJ	nudix hydrolase
FORC46_RS02210	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC46_RS02220	ENOG4105VB9	50S ribosomal protein l28
FORC46_RS02225	ENOG4105DJV	ribulose-phosphate 3-epimerase
FORC46_RS02255	ENOG4105KB8	(LipO)protein
FORC46_RS02270	ENOG4105CHV	Transcription elongation factor NusA
FORC46_RS02280	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
FORC46_RS02290	ENOG4105CB5	ATP-dependent DNA helicase recG
FORC46_RS02295	ENOG4105VIG	Sec-independent protein translocase protein TatC
FORC46_RS02305	ENOG4105E5Q	amino acid AbC transporter
FORC46_RS02310	ENOG4105DRP	amino acid AbC transporter
FORC46_RS02340	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FORC46_RS02360	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
FORC46_RS02365	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FORC46_RS02370	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FORC46_RS02380	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FORC46_RS02385	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FORC46_RS02395	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FORC46_RS02445	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
FORC46_RS02450	ENOG4105BZU	Histidine kinase
FORC46_RS02460	ENOG4105CK5	oxidoreductase
FORC46_RS02465	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FORC46_RS02470	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FORC46_RS02475	ENOG4107YJQ	MAF-like protein
FORC46_RS02480	ENOG4108JQC	penicillin-binding protein 1A
FORC46_RS02485	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FORC46_RS02490	ENOG4105VPX	protein, conserved in bacteria
FORC46_RS02495	ENOG4105CN1	protease
FORC46_RS02505	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
FORC46_RS02510	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
FORC46_RS02520	ENOG4105E9Q	Acyl-transferase
FORC46_RS02535	ENOG4105MGE	Rhodanese domain protein
FORC46_RS02555	ENOG41084DA	flagellar hook-basal body complex protein fliE
FORC46_RS02560	ENOG4108ZC9	flagellar basal-body rod protein flgc
FORC46_RS02565	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
FORC46_RS02585	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FORC46_RS02595	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FORC46_RS02605	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
FORC46_RS02610	ENOG4105DQU	oxidoreductase, subunit beta
FORC46_RS02630	ENOG4105EAH	synthase
FORC46_RS02635	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
FORC46_RS02640	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FORC46_RS02650	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FORC46_RS02655	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
FORC46_RS02665	ENOG4107TPX	flagellar hook-associated
FORC46_RS02685	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FORC46_RS02715	ENOG4105ME7	Membrane
FORC46_RS02720	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FORC46_RS02725	ENOG4105CAY	ferredoxin--nadp reductase
FORC46_RS02740	ENOG4105CDU	Replicative dna helicase
FORC46_RS02800	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FORC46_RS02805	ENOG4105KTH	gatB Yqey
FORC46_RS02810	ENOG4105C7K	acetolactate synthase
FORC46_RS02815	ENOG4108ZP8	Acetolactate synthase small subunit
FORC46_RS02825	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FORC46_RS02830	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FORC46_RS02840	ENOG4105CSA	Coproporphyrinogen iii oxidase
FORC46_RS02845	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FORC46_RS02850	ENOG4105CFH	Aspartokinase
FORC46_RS02865	ENOG4105EEI	dihydropteroate synthase
FORC46_RS02870	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FORC46_RS02885	ENOG4105DTN	riboflavin biosynthesis protein ribF
FORC46_RS02890	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
FORC46_RS02905	ENOG4105EN6	Membrane
FORC46_RS02915	ENOG4105CSM	endonuclease III
FORC46_RS02920	ENOG4105EIN	peptidylprolyl cis-trans isomerase
FORC46_RS02945	ENOG4105C8J	)-transporter
FORC46_RS02950	ENOG4108RPX	mosc domain containing protein
FORC46_RS02960	ENOG4105CSR	polyphosphate kinase 2
FORC46_RS02965	ENOG4105CH2	amidohydrolase
FORC46_RS02970	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
FORC46_RS02975	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FORC46_RS02980	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FORC46_RS02995	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
FORC46_RS03000	ENOG41090A1	ferritin
FORC46_RS03010	ENOG4105C8U	phosphate abc transporter
FORC46_RS03015	ENOG4105E2Z	phosphate ABC transporter (Permease
FORC46_RS03035	ENOG4105UQX	Mate efflux family protein
FORC46_RS03060	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
FORC46_RS03065	ENOG4105CQS	hydrogenase expression formation protein HypD
FORC46_RS03070	ENOG4105C45	hydrogenase expression formation protein (HypE)
FORC46_RS03075	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
FORC46_RS03090	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FORC46_RS03095	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FORC46_RS03105	ENOG4105C79	DNA protecting protein DprA
FORC46_RS03120	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FORC46_RS03125	ENOG4105F0N	pyrophosphate phospho-hydrolase
FORC46_RS03130	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FORC46_RS03135	ENOG4105C9M	aspartyl-trna synthetase
FORC46_RS03140	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FORC46_RS03145	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FORC46_RS03155	ENOG4105F8V	Hydrolase, tatD family
FORC46_RS03165	ENOG4105K6T	rare lipoprotein A
FORC46_RS03205	ENOG4105DUX	Transporter
FORC46_RS03230	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FORC46_RS03235	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
FORC46_RS03240	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
FORC46_RS03245	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FORC46_RS03250	ENOG4105CDH	Citrulline--aspartate ligase
FORC46_RS03255	ENOG410854I	s4 domain protein
FORC46_RS03265	ENOG4108IUZ	ABC transporter
FORC46_RS03270	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FORC46_RS03275	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
FORC46_RS03285	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
FORC46_RS03290	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
FORC46_RS03295	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
FORC46_RS03300	ENOG4105C08	Histidine kinase
FORC46_RS03305	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FORC46_RS03325	ENOG4105C25	Primosomal protein n'
FORC46_RS03335	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
FORC46_RS03340	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FORC46_RS03345	ENOG4105C6K	Malic enzyme
FORC46_RS03370	ENOG4105EIN	peptidylprolyl cis-trans isomerase
FORC46_RS03375	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FORC46_RS03380	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FORC46_RS03385	ENOG4105CGA	flagellar basal-body rod protein FlgG
FORC46_RS03390	ENOG4105CGA	flagellar basal-body rod protein FlgG
FORC46_RS03395	ENOG4105C5F	glutamine synthetase
FORC46_RS03405	ENOG4105CFP	Peptidase U32
FORC46_RS03420	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
FORC46_RS03425	ENOG4105EGD	dinuclear metal center protein, YbgI family
FORC46_RS03435	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
FORC46_RS03440	ENOG4105EI2	Pseudouridine synthase
FORC46_RS03445	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC46_RS03450	ENOG4105K5M	30s ribosomal protein S16
FORC46_RS03455	ENOG4105VB6	UPF0109 protein
FORC46_RS03460	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FORC46_RS03465	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FORC46_RS03470	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FORC46_RS03480	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
FORC46_RS03485	ENOG4105KUZ	arsenate reductase
FORC46_RS03495	ENOG4105C0B	DNA polymerase III (alpha subunit)
FORC46_RS03500	ENOG4105DFA	alanine racemase domain protein
FORC46_RS03515	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FORC46_RS03520	ENOG4105D0M	Protease HtpX homolog
FORC46_RS03530	ENOG4105M03	Domain of unknown function (DUF955)
FORC46_RS03570	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
FORC46_RS03575	ENOG4105D7N	magnesium and cobalt transport protein CorA
FORC46_RS03605	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FORC46_RS03685	ENOG4108122	heat-inducible transcription repressor
FORC46_RS03735	ENOG4105CHM	Aminotransferase
FORC46_RS03740	ENOG4105D7W	serine acetyltransferase
FORC46_RS03745	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
FORC46_RS03750	ENOG4105CUT	histidyl-tRNA synthetase
FORC46_RS03760	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FORC46_RS03765	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
FORC46_RS03775	ENOG4105D01	(LipO)protein
FORC46_RS03780	ENOG4105D01	(LipO)protein
FORC46_RS03785	ENOG4105D01	(LipO)protein
FORC46_RS03790	ENOG4108UMI	ABC transporter, permease
FORC46_RS03795	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FORC46_RS03810	ENOG4105C4R	Atp-dependent dna helicase
FORC46_RS03820	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
FORC46_RS03825	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FORC46_RS03830	ENOG4108BGM	Quinol dehydrogenase periplasmic component
FORC46_RS03835	ENOG4105GXZ	Ferredoxin-type protein NapH
FORC46_RS03840	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
FORC46_RS03875	ENOG4105CIY	formyltetrahydrofolate deformylase
FORC46_RS03915	ENOG4105CPF	Cell wall formation (By similarity)
FORC46_RS03920	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FORC46_RS03930	ENOG4105CJR	Integral membrane protein (MviN
FORC46_RS03935	ENOG4105C8N	cysteinyl-tRNA synthetase
FORC46_RS03940	ENOG4105BZ1	(ABC) transporter
FORC46_RS03945	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
FORC46_RS03960	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
FORC46_RS03975	ENOG4105C4K	Nad synthetase
FORC46_RS03980	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
FORC46_RS03985	ENOG4107QID	Threonine synthase
FORC46_RS03990	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
FORC46_RS04000	ENOG4107R0W	ABC transporter
FORC46_RS04015	ENOG4105CN7	Flagellar biosynthetic protein FliP
FORC46_RS04020	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FORC46_RS04050	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FORC46_RS04055	ENOG4105C7B	Threonine dehydratase
FORC46_RS04075	ENOG4107S6Z	Na H antiporter
FORC46_RS04080	ENOG4105EMU	Dehydrogenase
FORC46_RS04090	ENOG4107QIJ	Aconitate hydratase 2
FORC46_RS04095	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FORC46_RS04105	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FORC46_RS04115	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FORC46_RS04140	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FORC46_RS04145	ENOG4107RN3	metallophosphoesterase
FORC46_RS04150	ENOG4105DJ4	phosphatidylserine decarboxylase
FORC46_RS04155	ENOG4105D00	flagellar biosynthetic protein flhB
FORC46_RS04180	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FORC46_RS04190	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FORC46_RS04195	ENOG4105C3F	Signal peptidase i
FORC46_RS04200	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FORC46_RS04205	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FORC46_RS04220	ENOG4105DDQ	anthranilate synthase
FORC46_RS04225	ENOG4105CRQ	synthase (Component I)
FORC46_RS04230	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FORC46_RS04235	ENOG4108N92	Thiol disulfide Interchange Protein
FORC46_RS04240	ENOG4108PSN	Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity)
FORC46_RS04245	ENOG4108MR7	Arylsulfotransferase
FORC46_RS04285	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
FORC46_RS04290	ENOG4105D7B	Flagellar biosynthesis protein flha
FORC46_RS04300	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FORC46_RS04305	ENOG4105CNU	cell division protein FtsK
FORC46_RS04310	ENOG4105DTJ	flagellar hook-associated protein
FORC46_RS04325	ENOG4105C5H	ABC transporter
FORC46_RS04330	ENOG4105BZU	Histidine kinase
FORC46_RS04340	ENOG4108JQ1	Dehydrogenase
FORC46_RS04350	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FORC46_RS04360	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FORC46_RS04365	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FORC46_RS04370	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FORC46_RS04375	ENOG4105K59	histidine triad (HIT) protein
FORC46_RS04390	ENOG4105E5Q	amino acid AbC transporter
FORC46_RS04405	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
FORC46_RS04410	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FORC46_RS04435	ENOG4108ZX6	Electron transport protein SCO1 SenC
FORC46_RS04440	ENOG4105C6T	cysteine synthase
FORC46_RS04445	ENOG410841J	DNA-binding protein Hu
FORC46_RS04455	ENOG4105NAU	thioesterase Superfamily protein
FORC46_RS04465	ENOG4105D22	carbon starvation protein
FORC46_RS04470	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FORC46_RS04475	ENOG4105DRP	amino acid AbC transporter
FORC46_RS04480	ENOG4105EAD	ABC transporter
FORC46_RS04485	ENOG4107RP9	extracellular solute-binding protein, family 3
FORC46_RS04490	ENOG4105CDA	abc transporter atp-binding protein
FORC46_RS04495	ENOG4105BZU	Histidine kinase
FORC46_RS04500	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FORC46_RS04515	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FORC46_RS04525	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FORC46_RS04530	ENOG4105C3G	gtp-binding protein
FORC46_RS04535	ENOG4105CH7	arginosuccinase
FORC46_RS04540	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
FORC46_RS04545	ENOG4107QSA	Oxaloacetate decarboxylase
FORC46_RS04550	ENOG4105C8J	)-transporter
FORC46_RS04555	ENOG4105C8J	)-transporter
FORC46_RS04655	ENOG4105EAD	ABC transporter
FORC46_RS04665	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FORC46_RS04670	ENOG4105ZGC	lipoprotein carrier protein
FORC46_RS04680	ENOG4107QUV	Domain protein
FORC46_RS04695	ENOG41076HS	cation diffusion facilitator family transporter
FORC46_RS04710	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC46_RS04715	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FORC46_RS04720	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
FORC46_RS04725	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
FORC46_RS04740	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FORC46_RS04745	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
FORC46_RS04750	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FORC46_RS04770	ENOG4107YD3	Thioesterase
FORC46_RS04800	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
FORC46_RS04815	ENOG4105KK6	nuclease
FORC46_RS04820	ENOG4105CIN	aminoacyl-histidine dipeptidase
FORC46_RS04825	ENOG4105CSH	Transporter
FORC46_RS04830	ENOG4105CT1	(ABC) transporter
FORC46_RS04835	ENOG4108F5X	surface-exposed lipoprotein
FORC46_RS04840	ENOG410802Z	Protein of unknown function (DUF328)
FORC46_RS04845	ENOG4105CH2	amidohydrolase
FORC46_RS04850	ENOG4105EKN	Major Facilitator
FORC46_RS04870	ENOG4108F9G	
FORC46_RS04875	ENOG4105DF6	Fe-S oxidoreductase
FORC46_RS04880	ENOG4105D4P	Coproporphyrinogen iii oxidase
FORC46_RS04885	ENOG4105T1H	UPF0763 protein
FORC46_RS04890	ENOG4105DBV	ornithine carbamoyltransferase
FORC46_RS04895	ENOG4105D52	delta-aminolevulinic acid dehydratase
FORC46_RS04900	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
FORC46_RS04905	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
FORC46_RS04915	ENOG4105HMI	Membrane
FORC46_RS04920	ENOG4105DUM	transcriptional regulator, lysR family
FORC46_RS04925	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FORC46_RS04950	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FORC46_RS04960	ENOG4105D49	3-dehydroquinate synthase
FORC46_RS04970	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FORC46_RS04990	ENOG4105CRE	cytochrome C
FORC46_RS04995	ENOG4108IV0	ABC, transporter
FORC46_RS05000	ENOG4105C0Z	ABC transporter
FORC46_RS05005	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
FORC46_RS05010	ENOG4105C32	Amino acid ABC transporter (Permease)
FORC46_RS05015	ENOG4105CP9	extracellular ligand-binding receptor
FORC46_RS05040	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FORC46_RS05060	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FORC46_RS05075	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FORC46_RS05100	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
FORC46_RS05110	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FORC46_RS05115	ENOG4105CNI	cell division protein FtsW
FORC46_RS05120	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FORC46_RS05145	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FORC46_RS05150	ENOG4105D41	biosynthesis protein thiH
FORC46_RS05155	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FORC46_RS05170	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FORC46_RS05185	ENOG4105C98	muts2 protein
FORC46_RS05215	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FORC46_RS05235	ENOG4105CEV	competence damage-inducible protein
FORC46_RS05245	ENOG4108RCM	Nitroreductase
FORC46_RS05250	ENOG4108RCM	Nitroreductase
FORC46_RS05260	ENOG4105DZP	Membrane-associated zinc metalloprotease
FORC46_RS05265	ENOG4108MJ5	VirK protein
FORC46_RS05270	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
FORC46_RS05275	ENOG4108UUM	single-stranded DNA-binding protein
FORC46_RS05280	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FORC46_RS05285	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FORC46_RS05295	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
FORC46_RS05300	ENOG4105II7	pyrroline-5-carboxylate reductase
FORC46_RS05325	ENOG410820E	Thiamine monophosphate
FORC46_RS05330	ENOG4105DWF	phosphomethylpyrimidine kinase
FORC46_RS05345	ENOG4108JA2	transcriptioN-repair coupling factor
FORC46_RS05355	ENOG4105DR5	peptidase
FORC46_RS05360	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FORC46_RS05380	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FORC46_RS05385	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FORC46_RS05390	ENOG4105VIE	preprotein translocase, subunit YajC
FORC46_RS05395	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FORC46_RS05400	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FORC46_RS05405	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
FORC46_RS05415	ENOG4105DPN	Oligoendopeptidase f
FORC46_RS05425	ENOG4105C4R	Atp-dependent dna helicase
FORC46_RS05440	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FORC46_RS05445	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FORC46_RS05455	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
FORC46_RS05460	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FORC46_RS05465	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
FORC46_RS05470	ENOG4107SDU	Methyl-accepting chemotaxis
FORC46_RS05475	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
FORC46_RS05480	ENOG4105E0X	reductase
FORC46_RS05485	ENOG4105ED9	Protein of unknown function (DUF455)
FORC46_RS05490	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
FORC46_RS05500	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FORC46_RS05510	ENOG4108VYJ	response regulator receiver protein
FORC46_RS05520	ENOG4105C5E	polysaccharide biosynthesis protein
FORC46_RS05525	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FORC46_RS05535	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
FORC46_RS05540	ENOG4105D3Q	Sugar transferase
FORC46_RS05545	ENOG4105CGN	Glycosyl transferase (Group 1
FORC46_RS05550	ENOG4107ZAZ	Oligosaccharyl transferase, STT3 subunit
FORC46_RS05555	ENOG4105CG5	Glycosyl transferase (Group 1
FORC46_RS05560	ENOG4105K64	Glycosyl transferase, family 2
FORC46_RS05565	ENOG4105CG5	Glycosyl transferase (Group 1
FORC46_RS05570	ENOG4105BZ1	(ABC) transporter
FORC46_RS05575	ENOG4105CMR	udp-glucose 4-epimerase
FORC46_RS05585	ENOG4105D16	lipopolysaccharide heptosyltransferase i
FORC46_RS05590	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
FORC46_RS05615	ENOG4105I85	Bifunctional alpha-2,3 -2,8-sialyltransferase
FORC46_RS05620	ENOG4105D2T	synthase
FORC46_RS05625	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
FORC46_RS05635	ENOG4105EQK	-acetyltransferase
FORC46_RS05640	ENOG4107QRS	glycosyltransferase group 2 family protein
FORC46_RS05660	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
FORC46_RS05665	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
FORC46_RS05680	ENOG4105C59	p-type ATPase
FORC46_RS05685	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FORC46_RS05690	ENOG4107QMP	dna polymerase iii subunits gamma and tau
FORC46_RS05700	ENOG4105C59	p-type ATPase
FORC46_RS05720	ENOG4107XM3	UPF0442 protein
FORC46_RS05730	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FORC46_RS05735	ENOG4107T5V	SNARE associated Golgi
FORC46_RS05750	ENOG4108ZCU	PPIases accelerate the folding of proteins
FORC46_RS05755	ENOG4105CDY	transcriptional regulatory protein
FORC46_RS05760	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
FORC46_RS05775	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FORC46_RS05780	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FORC46_RS05790	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
FORC46_RS05795	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FORC46_RS05800	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FORC46_RS05805	ENOG4105CE9	30S ribosomal protein S2
FORC46_RS05810	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
FORC46_RS05820	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FORC46_RS05825	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FORC46_RS05830	ENOG4108KUF	arsenical pump membrane protein
FORC46_RS05835	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FORC46_RS05845	ENOG4107SDU	Methyl-accepting chemotaxis
FORC46_RS05855	ENOG4107QJT	sodium dicarboxylate symporter
FORC46_RS05875	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FORC46_RS05885	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
FORC46_RS05895	ENOG4105D01	(LipO)protein
FORC46_RS05905	ENOG4105SYT	Methylenetetrahydrofolate reductase
FORC46_RS05915	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
FORC46_RS05920	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FORC46_RS05925	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FORC46_RS05940	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
FORC46_RS05955	ENOG4107S2Z	UPF0761 membrane protein
FORC46_RS05960	ENOG4105CQB	FAD linked oxidase domain protein
FORC46_RS05970	ENOG4105DR5	peptidase
FORC46_RS05980	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
FORC46_RS05995	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FORC46_RS06000	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FORC46_RS06010	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
FORC46_RS06040	ENOG4105C0H	protease
FORC46_RS06045	ENOG4105DVC	DnaJ domain protein
FORC46_RS06050	ENOG4105KNI	merR family transcriptional Regulator
FORC46_RS06055	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FORC46_RS06070	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
FORC46_RS06075	ENOG4105DR5	peptidase
FORC46_RS06090	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FORC46_RS06105	ENOG4105F27	Major Facilitator
FORC46_RS06115	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FORC46_RS06120	ENOG41082XB	radical SAM domain protein
FORC46_RS06130	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FORC46_RS06140	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FORC46_RS06165	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FORC46_RS06175	ENOG4105VSH	4-oxalocrotonate tautomerase
FORC46_RS06190	ENOG4105KJF	protein tyrosine phosphatase
FORC46_RS06195	ENOG4105YIC	Major outer membrane protein
FORC46_RS06200	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FORC46_RS06220	ENOG4108USZ	hydrogenase
FORC46_RS06225	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
FORC46_RS06230	ENOG4105DPX	Hydrogenase, large subunit
FORC46_RS06235	ENOG4105E3S	small subunit
FORC46_RS06240	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
FORC46_RS06245	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FORC46_RS06255	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FORC46_RS06260	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FORC46_RS06265	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FORC46_RS06270	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FORC46_RS06285	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FORC46_RS06290	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FORC46_RS06300	ENOG4105C34	Pseudouridine synthase
FORC46_RS06305	ENOG4105CNI	cell division protein FtsW
FORC46_RS06320	ENOG4105CZN	Potassium uptake protein
FORC46_RS06330	ENOG4108XUR	Pfam:DUF178
FORC46_RS06340	ENOG4105C6K	Malic enzyme
FORC46_RS06345	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FORC46_RS06355	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FORC46_RS06360	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
FORC46_RS06370	ENOG4105C5E	polysaccharide biosynthesis protein
FORC46_RS06375	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FORC46_RS06380	ENOG4105EQQ	protein containing aminopeptidase domain
FORC46_RS06415	ENOG4108P1X	synthase
FORC46_RS06455	ENOG4105F0R	Cytidylyltransferase
FORC46_RS06460	ENOG4107DKY	pseudaminic acid biosynthesis-associated protein PseG
FORC46_RS06465	ENOG4105VDT	-acetyltransferase
FORC46_RS06470	ENOG4105I2C	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FORC46_RS06475	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
FORC46_RS06525	ENOG4108VAU	general secretion pathway protein G
FORC46_RS06530	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FORC46_RS06540	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
FORC46_RS06545	ENOG4105KNE	Phosphatidate cytidylyltransferase
FORC46_RS06560	ENOG41080AZ	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
FORC46_RS06565	ENOG4105HDD	phospholipase
FORC46_RS06570	ENOG4105DHS	permease protein
FORC46_RS06575	ENOG4105CM4	permease protein
FORC46_RS06580	ENOG4108IPW	abc transporter atp-binding protein
FORC46_RS06610	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
FORC46_RS06615	ENOG4105CUW	cytochrome C-TYPE protein
FORC46_RS06620	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FORC46_RS06635	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FORC46_RS06640	ENOG4105F4G	Membrane
FORC46_RS06645	ENOG4105C9Q	fumarate hydratase class II
FORC46_RS06655	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FORC46_RS06665	ENOG4105DVY	radical SAM domain protein
FORC46_RS06670	ENOG4105C7N	Xanthine uracil vitamin C permease
FORC46_RS06675	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
FORC46_RS06700	ENOG4107RDB	Major Facilitator
FORC46_RS06720	ENOG4105EM7	Selenocysteine-specific translation elongation factor
FORC46_RS06725	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
FORC46_RS06735	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
FORC46_RS06750	ENOG4105CH6	catalase
FORC46_RS06760	ENOG4105WWK	YheO domain protein
FORC46_RS06765	ENOG4105KME	endoribonuclease L-psp
FORC46_RS06770	ENOG4105CEE	C4-dicarboxylate transporter
FORC46_RS06780	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
FORC46_RS06790	ENOG4107K9B	ferrous iron transport protein
FORC46_RS06795	ENOG4105CE1	Ferrous iron transport protein b
FORC46_RS06800	ENOG4105E3S	small subunit
FORC46_RS06805	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
FORC46_RS06810	ENOG4105CP7	Triose-phosphate isomerase
FORC46_RS06815	ENOG4105BZA	Phosphoglycerate kinase
FORC46_RS06820	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FORC46_RS06840	ENOG4107QKV	phosphomannomutase
FORC46_RS06845	ENOG4105X6C	Flagellar basal body-associated protein FliL
FORC46_RS06870	ENOG41084CK	capsule polysaccharide
FORC46_RS06880	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
FORC46_RS06885	ENOG4107Z36	nucleotidyl transferase
FORC46_RS06890	ENOG41082DT	Glutamine amido-transferase
FORC46_RS06895	ENOG4105P12	pyruvate phosphate dikinase
FORC46_RS06900	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FORC46_RS06940	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
FORC46_RS06950	ENOG4105C2X	Arabinose 5-phosphate isomerase
FORC46_RS06955	ENOG4107V1M	polysaccharide export protein
FORC46_RS06960	ENOG4105ECX	polysaccharide export
FORC46_RS06970	ENOG41090SZ	ABC-2 type transporter
FORC46_RS07005	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
FORC46_RS07010	ENOG4105I85	Bifunctional alpha-2,3 -2,8-sialyltransferase
FORC46_RS07015	ENOG4105C11	sulfate adenylyltransferase), subunit 2
FORC46_RS07020	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
FORC46_RS07030	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
FORC46_RS07055	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FORC46_RS07085	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FORC46_RS07120	ENOG4105YKR	
FORC46_RS07145	ENOG4105EJ9	Membrane
FORC46_RS07150	ENOG4105D7Q	type ii secretion system
FORC46_RS07155	ENOG4107QHF	type ii secretion system protein e
FORC46_RS07185	ENOG4107XGZ	Hydrolase
FORC46_RS07190	ENOG4105CDV	Ompa motb domain protein
FORC46_RS07195	ENOG4108UJD	30S ribosomal protein S9
FORC46_RS07200	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FORC46_RS07205	ENOG4105C4R	Atp-dependent dna helicase
FORC46_RS07210	ENOG4107RMM	double-strand break repair protein Addb
FORC46_RS07255	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FORC46_RS07270	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FORC46_RS07290	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FORC46_RS07300	ENOG41066VF	YeeE YedE family protein
FORC46_RS07310	ENOG4105CK7	Sodium proline symporter
FORC46_RS07330	ENOG4107SDU	Methyl-accepting chemotaxis
FORC46_RS07340	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
FORC46_RS07350	ENOG4105QAX	Iron-sulfur
FORC46_RS07385	ENOG4108ZEX	molybdopterin converting factor, subunit 2
FORC46_RS07390	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FORC46_RS07395	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
FORC46_RS07405	ENOG4105E9M	CRISPR-associated protein, Csn1 family
FORC46_RS07415	ENOG4105CEE	C4-dicarboxylate transporter
FORC46_RS07420	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FORC46_RS07430	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
FORC46_RS07435	ENOG4108UR8	BAX protein
FORC46_RS07445	ENOG4108RMU	ferritin dps family protein
FORC46_RS07450	ENOG4107QP8	phosphohexose isomerase
FORC46_RS07455	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FORC46_RS07460	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FORC46_RS07465	ENOG41078M4	ABC transporter
FORC46_RS07470	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
FORC46_RS07475	ENOG4105C8W	ABC transporter
FORC46_RS07480	ENOG4105E7W	lamb ycsf family protein
FORC46_RS07485	ENOG4105P4J	Allophanate hydrolase, subunit 1
FORC46_RS07490	ENOG4107R7A	Allophanate hydrolase subunit 2
FORC46_RS07500	ENOG4105NF4	modulator of drug activity
FORC46_RS07505	ENOG4105KVH	Transcriptional regulator
FORC46_RS07515	ENOG4105DQ4	alcohol dehydrogenase
FORC46_RS07530	ENOG4107XZC	Restriction modification system DNA (Specificity
FORC46_RS07535	ENOG4107R3N	Filamentation induced by cAMP protein fic
FORC46_RS07560	ENOG41085FC	arsR family transcriptional regulator
FORC46_RS07590	ENOG4105C8S	subunit m
FORC46_RS07595	ENOG4105D65	subunit l
FORC46_RS07600	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FORC46_RS07640	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FORC46_RS07645	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FORC46_RS07650	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FORC46_RS07665	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FORC46_RS07670	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FORC46_RS07705	ENOG4105IBP	Cyclic peptide transporter
FORC46_RS07710	ENOG4105CSH	Transporter
FORC46_RS07715	ENOG4108W8B	Beta-lactamase domain protein
FORC46_RS07720	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FORC46_RS07725	ENOG41067V7	50S ribosomal protein L36
FORC46_RS07730	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FORC46_RS07740	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FORC46_RS07745	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FORC46_RS07750	ENOG4108ZT0	50S ribosomal protein l17
FORC46_RS07755	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FORC46_RS07765	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FORC46_RS07775	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
FORC46_RS07790	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FORC46_RS07795	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
FORC46_RS07800	ENOG4105D1F	ATP-binding protein
FORC46_RS07805	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FORC46_RS07815	ENOG4107RIQ	Sulfate adenylate transferase
FORC46_RS07820	ENOG4108ZAI	phosphatidylglycerophosphatase a
FORC46_RS07825	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
FORC46_RS07835	ENOG4108WHG	pyridoxamine 5'-phosphate
FORC46_RS07840	ENOG4105D05	Receptor
FORC46_RS07845	ENOG4105EHG	Permease protein
FORC46_RS07850	ENOG4105E0A	ABC, transporter
FORC46_RS07855	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
FORC46_RS07865	ENOG4105CSH	Transporter
FORC46_RS07870	ENOG4105CEN	a g-specific adenine glycosylase
FORC46_RS07910	ENOG4105EJQ	L-serine dehydratase
FORC46_RS07915	ENOG4105C44	Serine transporter
FORC46_RS07930	ENOG4105M8K	biopolymer transport protein
FORC46_RS07935	ENOG4105M15	transport protein ExbD
FORC46_RS07960	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FORC46_RS07980	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FORC46_RS07995	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FORC46_RS08000	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FORC46_RS08015	ENOG4105CV1	Transketolase (EC 2.2.1.1)
FORC46_RS08025	ENOG4105DHJ	ABC, transporter
FORC46_RS08035	ENOG4108SNX	Mammalian cell entry related domain protein
FORC46_RS08045	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FORC46_RS08050	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FORC46_RS08055	ENOG4108QBX	(LipO)protein
FORC46_RS08065	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FORC46_RS08080	ENOG4107SJW	iron permease, FTR1
FORC46_RS08105	ENOG4105C19	ABC transporter
FORC46_RS08170	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FORC46_RS08175	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FORC46_RS08180	ENOG4105E63	Pfam:DUF178
FORC46_RS08185	ENOG4105VS8	Flagellar biosynthetic protein fliq
FORC46_RS08200	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
FORC46_RS08205	ENOG4105BZN	citrate synthase
FORC46_RS08215	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FORC46_RS08220	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FORC46_RS08230	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
FORC46_RS08240	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FORC46_RS08245	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FORC46_RS08250	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FORC46_RS08255	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
FORC46_RS08260	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FORC46_RS08265	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FORC46_RS08270	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FORC46_RS08275	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FORC46_RS08280	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FORC46_RS08285	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FORC46_RS08290	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FORC46_RS08295	ENOG41084HJ	50s ribosomal protein l29
FORC46_RS08300	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FORC46_RS08305	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FORC46_RS08310	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FORC46_RS08315	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FORC46_RS08325	ENOG4105KZZ	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FORC46_RS08330	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FORC46_RS08335	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FORC46_RS08340	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FORC46_RS08345	ENOG4105FE9	pseudouridine synthase
FORC46_RS08350	ENOG4105CN5	Metallo-Beta-Lactamase
FORC46_RS08365	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FORC46_RS08410	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FORC46_RS08415	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FORC46_RS08435	ENOG4105DVP	Adenine-specific
FORC46_RS08450	ENOG4106NNP	ICEA Protein
FORC46_RS08460	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
FORC46_RS08465	ENOG4105BZE	flagellar hook protein, FlgE
FORC46_RS08470	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
FORC46_RS08590	ENOG41071TK	Uncharacterised protein family (UPF0150)
FORC46_RS08615	ENOG4108C33	Resolvase
FORC46_RS08640	ENOG4106050	phage regulatory protein, rha family
FORC46_RS08650	ENOG4108UUM	single-stranded DNA-binding protein
FORC46_RS08680	ENOG4105EGP	transfer protein
FORC46_RS08720	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FORC46_RS08850	ENOG4107QJE	Chromosome Partitioning Protein
FORC46_RS08940	ENOG4106050	phage regulatory protein, rha family
