locus-tag	class	description
E8M85_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E8M85_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E8M85_RS00015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E8M85_RS00030	ENOG4105D3Y	Na H antiporter
E8M85_RS00040	ENOG4105BZ8	glutamate synthase
E8M85_RS00055	ENOG4108RAC	Rubrerythrin
E8M85_RS00060	ENOG4105C01	Dihydroxy-acid dehydratase
E8M85_RS00065	ENOG4105R3P	Inner membrane protein yagU
E8M85_RS00075	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
E8M85_RS00090	ENOG4105C8Q	Methyl-accepting chemotaxis
E8M85_RS00095	ENOG4105CA0	peroxidase
E8M85_RS00100	ENOG4105ERH	Fumarylacetoacetate hydrolase
E8M85_RS00105	ENOG4105EI2	Pseudouridine synthase
E8M85_RS00110	ENOG4107QTF	adenylosuccinate lyase
E8M85_RS00115	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E8M85_RS00130	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
E8M85_RS00135	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E8M85_RS00140	ENOG4107RB3	L-asparaginase
E8M85_RS00180	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
E8M85_RS00270	ENOG4105QIB	mu-like prophage Flumu protein gp29
E8M85_RS00315	ENOG4105EFV	Major head subunit
E8M85_RS00460	ENOG4105C2C	drug resistance transporter, Bcr CflA
E8M85_RS00480	ENOG4105CI3	gtp-binding protein typa
E8M85_RS00495	ENOG410822I	Flagellar hook capping protein
E8M85_RS00500	ENOG4105BZE	flagellar hook protein, FlgE
E8M85_RS00535	ENOG4107QPK	)-transporter
E8M85_RS00540	ENOG4107QPK	)-transporter
E8M85_RS00580	ENOG4105DD5	Flagellar motor switch protein
E8M85_RS00585	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E8M85_RS00590	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8M85_RS00600	ENOG4107R21	site-determining protein
E8M85_RS00605	ENOG4105FZW	flagellar biosynthesis regulator FlhF
E8M85_RS00610	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E8M85_RS00615	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
E8M85_RS00620	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
E8M85_RS00625	ENOG4105D07	Signal peptide peptidase, SppA
E8M85_RS00650	ENOG4107QR9	Iron-sulfur cluster binding protein
E8M85_RS00655	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
E8M85_RS00660	ENOG4105DAA	L-lactate
E8M85_RS00670	ENOG4108TMH	cytolethal distending toxin
E8M85_RS00675	ENOG4106BMH	cytolethal distending toxin
E8M85_RS00685	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E8M85_RS00690	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E8M85_RS00700	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
E8M85_RS00705	ENOG4108IJ0	Aspartate ammonia-lyase
E8M85_RS00710	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
E8M85_RS00740	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
E8M85_RS00745	ENOG4105K46	50S ribosomal protein l27
E8M85_RS00750	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E8M85_RS00760	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
E8M85_RS00765	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
E8M85_RS00770	ENOG4107QJE	Chromosome Partitioning Protein
E8M85_RS00775	ENOG4105FA0	parb-like partition protein
E8M85_RS00785	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
E8M85_RS00790	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E8M85_RS00800	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
E8M85_RS00805	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E8M85_RS00810	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
E8M85_RS00815	ENOG4105E02	MotA TolQ exbB proton channel
E8M85_RS00820	ENOG4105M8F	Biopolymer transport protein exbD tolR
E8M85_RS00830	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
E8M85_RS00835	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
E8M85_RS00845	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
E8M85_RS00850	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E8M85_RS00855	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
E8M85_RS00860	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
E8M85_RS00885	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E8M85_RS00895	ENOG4105SCY	DNAK suppressor
E8M85_RS00900	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
E8M85_RS00905	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
E8M85_RS00910	ENOG4105ECY	inositol monophosphatase
E8M85_RS00915	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E8M85_RS00930	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E8M85_RS00940	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
E8M85_RS00950	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
E8M85_RS00965	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
E8M85_RS00980	ENOG4105FDK	ABC transporter
E8M85_RS00990	ENOG4105C8Q	Methyl-accepting chemotaxis
E8M85_RS01000	ENOG4105C3M	thioredoxin reductase
E8M85_RS01005	ENOG4105K63	Thioredoxin
E8M85_RS01010	ENOG41082UM	UPF0102 protein
E8M85_RS01015	ENOG4105D6E	homoserine dehydrogenase
E8M85_RS01020	ENOG4105CHM	Aminotransferase
E8M85_RS01035	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E8M85_RS01045	ENOG41082DI	50s ribosomal protein l31
E8M85_RS01050	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E8M85_RS01070	ENOG4107XWN	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E8M85_RS01075	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E8M85_RS01100	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
E8M85_RS01115	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E8M85_RS01160	ENOG4105CWK	Biopolymer transport protein, ExbB
E8M85_RS01165	ENOG4108ZZF	transport protein (ExbD)
E8M85_RS01175	ENOG4108DQG	in Escherichia coli SbmA is involved in uptake of microcin J25
E8M85_RS01180	ENOG4105C37	(CBS) domain
E8M85_RS01190	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E8M85_RS01195	ENOG4105EE5	Membrane protein terC
E8M85_RS01200	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E8M85_RS01205	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E8M85_RS01215	ENOG4105C0P	Mg chelatase subunit ChlI
E8M85_RS01220	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E8M85_RS01230	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
E8M85_RS01235	ENOG4105EUJ	GTP cyclohydrolase i
E8M85_RS01240	ENOG4108JIR	Flagellum-specific ATP synthase
E8M85_RS01250	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
E8M85_RS01255	ENOG4105D1H	recombination factor protein RarA
E8M85_RS01280	ENOG4105D4T	Citrate transporter
E8M85_RS01285	ENOG4105EPD	Oligopeptide transporter, Opt family
E8M85_RS01290	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E8M85_RS01295	ENOG4105C22	threonyL-tRNA synthetase
E8M85_RS01355	ENOG4105CAS	nag kinase
E8M85_RS01360	ENOG4105C8Y	Acetylornithine aminotransferase
E8M85_RS01365	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E8M85_RS01380	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E8M85_RS01400	ENOG4105NU9	Preprotein translocase subunit SecG
E8M85_RS01405	ENOG4105HFZ	Membrane
E8M85_RS01410	ENOG4107B2H	carbonic anhydrase
E8M85_RS01415	ENOG4105D64	Mechanosensitive ion channel
E8M85_RS01420	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
E8M85_RS01440	ENOG41084M8	50s ribosomal protein L35
E8M85_RS01445	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
E8M85_RS01450	ENOG4108NVR	Methyl-accepting chemotaxis
E8M85_RS01475	ENOG4105CSH	Transporter
E8M85_RS01485	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E8M85_RS01490	ENOG41068HQ	Protein of unknown function (DUF493)
E8M85_RS01500	ENOG4105CGK	Exodeoxyribonuclease III
E8M85_RS01505	ENOG4105DIJ	Phosphoethanolamine transferase
E8M85_RS01510	ENOG41080IJ	Diacylglycerol kinase
E8M85_RS01520	ENOG4105EKE	dihydroorotase
E8M85_RS01530	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E8M85_RS01535	ENOG4105C8Q	Methyl-accepting chemotaxis
E8M85_RS01540	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
E8M85_RS01545	ENOG4107QY8	reductase
E8M85_RS01565	ENOG4105EPW	hflc protein
E8M85_RS01570	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E8M85_RS01575	ENOG4108F90	4-oxalocrotonate tautomerase
E8M85_RS01580	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E8M85_RS01585	ENOG4105WPN	DNA integration recombination invertion protein
E8M85_RS01595	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E8M85_RS01600	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
E8M85_RS01615	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E8M85_RS01660	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E8M85_RS01685	ENOG4108HYG	acetyltransferase
E8M85_RS01715	ENOG4105E0C	molybdate abc transporter
E8M85_RS01725	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E8M85_RS01730	ENOG410825B	Type 11 methyltransferase
E8M85_RS01735	ENOG4105HSA	Protein of unknown function (DUF452)
E8M85_RS01740	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E8M85_RS01745	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E8M85_RS01750	ENOG4107S77	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
E8M85_RS01755	ENOG41080TC	multidrug resistance protein
E8M85_RS01780	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E8M85_RS01790	ENOG4105CQC	Prephenate dehydratase
E8M85_RS01795	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E8M85_RS01800	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
E8M85_RS01805	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E8M85_RS01815	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E8M85_RS01830	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E8M85_RS01835	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E8M85_RS01840	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
E8M85_RS01845	ENOG4105M4H	endoribonuclease L-psp
E8M85_RS01850	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E8M85_RS01855	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
E8M85_RS01860	ENOG4105YQ2	50s ribosomal protein l32
E8M85_RS01870	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
E8M85_RS01880	ENOG4105D3R	alkyl hydroperoxide reductase
E8M85_RS01885	ENOG4105D00	flagellar biosynthetic protein flhB
E8M85_RS01890	ENOG4108SEK	ompa motb domain protein
E8M85_RS01895	ENOG4105E14	MotA TolQ exbB proton channel
E8M85_RS01900	ENOG4105C2M	dna polymerase I
E8M85_RS01920	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E8M85_RS01940	ENOG4108EFP	Anthranilate synthase component II
E8M85_RS01950	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E8M85_RS01965	ENOG4105DD5	Flagellar motor switch protein
E8M85_RS01980	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E8M85_RS01985	ENOG4105ETX	regulatoR
E8M85_RS01995	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
E8M85_RS02000	ENOG4105CA0	peroxidase
E8M85_RS02010	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E8M85_RS02015	ENOG4108YXA	Membrane
E8M85_RS02020	ENOG4105CSA	Coproporphyrinogen iii oxidase
E8M85_RS02030	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E8M85_RS02040	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
E8M85_RS02055	ENOG41082DJ	30S ribosomal protein S21
E8M85_RS02060	ENOG4108UHV	Lipoprotein
E8M85_RS02065	ENOG4106032	Glutathionylspermidine synthase
E8M85_RS02070	ENOG4105C5I	Dehydrogenase
E8M85_RS02075	ENOG4108VPT	UPF0234 protein
E8M85_RS02090	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E8M85_RS02100	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
E8M85_RS02110	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
E8M85_RS02120	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E8M85_RS02150	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
E8M85_RS02165	ENOG4105CA9	Pyruvate kinase
E8M85_RS02170	ENOG4107RSR	Malate quinone oxidoreductase
E8M85_RS02175	ENOG4108VHG	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
E8M85_RS02185	ENOG4108TX7	
E8M85_RS02210	ENOG4105CRK	lysyL-tRNA synthetase
E8M85_RS02215	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E8M85_RS02230	ENOG4105E2X	shikimate dehydrogenase
E8M85_RS02245	ENOG4108S24	Fumarate reduCtase
E8M85_RS02250	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
E8M85_RS02255	ENOG4105E33	succinate dehydrogenase
E8M85_RS02300	ENOG4108YYC	ycei family
E8M85_RS02330	ENOG4105C5H	ABC transporter
E8M85_RS02345	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
E8M85_RS02385	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
E8M85_RS02390	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
E8M85_RS02395	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E8M85_RS02400	ENOG4105CHR	reductase
E8M85_RS02410	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
E8M85_RS02415	ENOG4105E33	succinate dehydrogenase
E8M85_RS02420	ENOG41086B8	CoB-CoM heterodisulfide reductase
E8M85_RS02425	ENOG4105ETU	transcriptional activator (TenA
E8M85_RS02430	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E8M85_RS02435	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E8M85_RS02440	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
E8M85_RS02455	ENOG4105D05	Receptor
E8M85_RS02460	ENOG4107VIJ	nudix hydrolase
E8M85_RS02465	ENOG4107SDU	Methyl-accepting chemotaxis
E8M85_RS02475	ENOG4105VB9	50S ribosomal protein l28
E8M85_RS02480	ENOG4105DJV	ribulose-phosphate 3-epimerase
E8M85_RS02510	ENOG4105KB8	(LipO)protein
E8M85_RS02515	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E8M85_RS02525	ENOG4105CHV	Transcription elongation factor NusA
E8M85_RS02535	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
E8M85_RS02545	ENOG4105CB5	ATP-dependent DNA helicase recG
E8M85_RS02550	ENOG4105VIG	Sec-independent protein translocase protein TatC
E8M85_RS02560	ENOG4105E5Q	amino acid AbC transporter
E8M85_RS02565	ENOG4105E5Q	amino acid AbC transporter
E8M85_RS02595	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E8M85_RS02615	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E8M85_RS02620	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
E8M85_RS02625	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E8M85_RS02630	ENOG4108VZM	50s ribosomal protein L10
E8M85_RS02635	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
E8M85_RS02640	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E8M85_RS02645	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E8M85_RS02655	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E8M85_RS02665	ENOG4105CTX	dehydratase
E8M85_RS02675	ENOG4105CHR	reductase
E8M85_RS02680	ENOG4105EDR	glucose galactose transporter
E8M85_RS02690	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
E8M85_RS02700	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E8M85_RS02750	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
E8M85_RS02760	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
E8M85_RS02765	ENOG4105CK5	oxidoreductase
E8M85_RS02770	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E8M85_RS02775	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
E8M85_RS02780	ENOG4107YJQ	MAF-like protein
E8M85_RS02785	ENOG4108JQC	penicillin-binding protein 1A
E8M85_RS02790	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E8M85_RS02795	ENOG4105VPX	protein, conserved in bacteria
E8M85_RS02800	ENOG4105CN1	protease
E8M85_RS02810	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
E8M85_RS02815	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
E8M85_RS02825	ENOG4105E9Q	Acyl-transferase
E8M85_RS02830	ENOG4105WMR	Protein CrcB homolog
E8M85_RS02840	ENOG4105MGE	Rhodanese domain protein
E8M85_RS02860	ENOG41084DA	flagellar hook-basal body complex protein fliE
E8M85_RS02865	ENOG4108ZC9	flagellar basal-body rod protein flgc
E8M85_RS02870	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
E8M85_RS02890	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
E8M85_RS02900	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E8M85_RS02910	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
E8M85_RS02915	ENOG4105DQU	oxidoreductase, subunit beta
E8M85_RS02935	ENOG4105EAH	synthase
E8M85_RS02940	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
E8M85_RS02945	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
E8M85_RS02955	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E8M85_RS02960	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
E8M85_RS02970	ENOG4107TPX	flagellar hook-associated
E8M85_RS02990	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E8M85_RS03020	ENOG4105ME7	Membrane
E8M85_RS03025	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
E8M85_RS03030	ENOG4105CAY	ferredoxin--nadp reductase
E8M85_RS03045	ENOG4105CDU	Replicative dna helicase
E8M85_RS03060	ENOG4108QDQ	Ubiquinol-cytochrome C chaperone 
E8M85_RS03065	ENOG4108QDQ	Ubiquinol-cytochrome C chaperone 
E8M85_RS03110	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E8M85_RS03115	ENOG4105KTH	gatB Yqey
E8M85_RS03120	ENOG4105C7K	acetolactate synthase
E8M85_RS03125	ENOG4108ZP8	Acetolactate synthase small subunit
E8M85_RS03135	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
E8M85_RS03140	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
E8M85_RS03150	ENOG4105CSA	Coproporphyrinogen iii oxidase
E8M85_RS03155	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E8M85_RS03160	ENOG4105CFH	Aspartokinase
E8M85_RS03175	ENOG4105EEI	dihydropteroate synthase
E8M85_RS03180	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E8M85_RS03195	ENOG4105DTN	riboflavin biosynthesis protein ribF
E8M85_RS03200	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
E8M85_RS03215	ENOG4105EN6	Membrane
E8M85_RS03225	ENOG4105CSM	endonuclease III
E8M85_RS03230	ENOG4105EIN	peptidylprolyl cis-trans isomerase
E8M85_RS03235	ENOG4105D2N	Aldolase
E8M85_RS03255	ENOG4105C8J	)-transporter
E8M85_RS03260	ENOG4108RPX	mosc domain containing protein
E8M85_RS03270	ENOG4105CSR	polyphosphate kinase 2
E8M85_RS03275	ENOG4105CH2	amidohydrolase
E8M85_RS03280	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E8M85_RS03285	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E8M85_RS03290	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E8M85_RS03305	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
E8M85_RS03310	ENOG41090A1	ferritin
E8M85_RS03320	ENOG4105C8U	phosphate abc transporter
E8M85_RS03325	ENOG4105E2Z	phosphate ABC transporter (Permease
E8M85_RS03630	ENOG4105UQX	Mate efflux family protein
E8M85_RS03655	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
E8M85_RS03660	ENOG4105CQS	hydrogenase expression formation protein HypD
E8M85_RS03665	ENOG4105C45	hydrogenase expression formation protein (HypE)
E8M85_RS03670	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
E8M85_RS03690	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E8M85_RS03695	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
E8M85_RS03705	ENOG4105C79	DNA protecting protein DprA
E8M85_RS03725	ENOG4105F0N	pyrophosphate phospho-hydrolase
E8M85_RS03735	ENOG4105C9M	aspartyl-trna synthetase
E8M85_RS03740	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E8M85_RS03745	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E8M85_RS03755	ENOG4105F8V	Hydrolase, tatD family
E8M85_RS03765	ENOG4105K6T	rare lipoprotein A
E8M85_RS03785	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
E8M85_RS03825	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
E8M85_RS03830	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
E8M85_RS03845	ENOG4105CDH	Citrulline--aspartate ligase
E8M85_RS03850	ENOG41082I2	s4 domain protein
E8M85_RS03860	ENOG4108IUZ	ABC transporter
E8M85_RS03865	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8M85_RS03870	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
E8M85_RS03885	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E8M85_RS03895	ENOG4105C08	Histidine kinase
E8M85_RS03900	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E8M85_RS03920	ENOG4105C25	Primosomal protein n'
E8M85_RS03930	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
E8M85_RS03940	ENOG4105C6K	Malic enzyme
E8M85_RS03965	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
E8M85_RS03970	ENOG4105EIN	peptidylprolyl cis-trans isomerase
E8M85_RS03975	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E8M85_RS03980	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E8M85_RS03985	ENOG4105CGA	flagellar basal-body rod protein FlgG
E8M85_RS03990	ENOG4105CGA	flagellar basal-body rod protein FlgG
E8M85_RS03995	ENOG4105C5F	glutamine synthetase
E8M85_RS04005	ENOG4105CFP	Peptidase U32
E8M85_RS04020	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
E8M85_RS04025	ENOG4105EGD	dinuclear metal center protein, YbgI family
E8M85_RS04035	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
E8M85_RS04040	ENOG4105EI2	Pseudouridine synthase
E8M85_RS04045	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E8M85_RS04050	ENOG4105K5M	30s ribosomal protein S16
E8M85_RS04055	ENOG4105VB6	UPF0109 protein
E8M85_RS04060	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E8M85_RS04065	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
E8M85_RS04080	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
E8M85_RS04085	ENOG4105KUZ	arsenate reductase
E8M85_RS04095	ENOG4105C0B	DNA polymerase III (alpha subunit)
E8M85_RS04100	ENOG4105DFA	alanine racemase domain protein
E8M85_RS04105	ENOG41090FP	flagellin
E8M85_RS04115	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E8M85_RS04120	ENOG4105D0M	Protease HtpX homolog
E8M85_RS04130	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E8M85_RS04135	ENOG4105D7N	magnesium and cobalt transport protein CorA
E8M85_RS04165	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8M85_RS04240	ENOG4105D7V	transposase
E8M85_RS04245	ENOG41067XB	TonB family
E8M85_RS04250	ENOG4105D05	Receptor
E8M85_RS04255	ENOG4108122	heat-inducible transcription repressor
E8M85_RS04260	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E8M85_RS04265	ENOG4105CFG	Acts as a chaperone (By similarity)
E8M85_RS04280	ENOG4105CHM	Aminotransferase
E8M85_RS04285	ENOG4105D7W	serine acetyltransferase
E8M85_RS04290	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
E8M85_RS04305	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
E8M85_RS04310	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
E8M85_RS04320	ENOG4105D01	(LipO)protein
E8M85_RS04325	ENOG4105D01	(LipO)protein
E8M85_RS04330	ENOG4105D01	(LipO)protein
E8M85_RS04335	ENOG4108UMI	ABC transporter, permease
E8M85_RS04340	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E8M85_RS04355	ENOG4105C4R	Atp-dependent dna helicase
E8M85_RS04365	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
E8M85_RS04370	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
E8M85_RS04375	ENOG4108BGM	Quinol dehydrogenase periplasmic component
E8M85_RS04380	ENOG4105GXZ	Ferredoxin-type protein NapH
E8M85_RS04385	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
E8M85_RS04415	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
E8M85_RS04420	ENOG4105CIY	formyltetrahydrofolate deformylase
E8M85_RS04460	ENOG4105CPF	Cell wall formation (By similarity)
E8M85_RS04465	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
E8M85_RS04475	ENOG4105CJR	Integral membrane protein (MviN
E8M85_RS04480	ENOG4105C8N	cysteinyl-tRNA synthetase
E8M85_RS04485	ENOG4105BZ1	(ABC) transporter
E8M85_RS04490	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E8M85_RS04500	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E8M85_RS04505	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
E8M85_RS04520	ENOG4105C4K	Nad synthetase
E8M85_RS04525	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
E8M85_RS04530	ENOG4107QID	Threonine synthase
E8M85_RS04535	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
E8M85_RS04550	ENOG4107R0W	ABC transporter
E8M85_RS04565	ENOG4105CN7	Flagellar biosynthetic protein FliP
E8M85_RS04570	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E8M85_RS04600	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E8M85_RS04605	ENOG4105C7B	Threonine dehydratase
E8M85_RS04620	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E8M85_RS04625	ENOG4107S6Z	Na H antiporter
E8M85_RS04630	ENOG4105EMU	Dehydrogenase
E8M85_RS04640	ENOG4107QIJ	Aconitate hydratase 2
E8M85_RS04645	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E8M85_RS04655	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E8M85_RS04665	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
E8M85_RS04690	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
E8M85_RS04695	ENOG4107RN3	metallophosphoesterase
E8M85_RS04700	ENOG4105DJ4	phosphatidylserine decarboxylase
E8M85_RS04705	ENOG4105D00	flagellar biosynthetic protein flhB
E8M85_RS04745	ENOG4105C3F	Signal peptidase i
E8M85_RS04750	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E8M85_RS04765	ENOG4105DDQ	anthranilate synthase
E8M85_RS04770	ENOG4105CRQ	synthase (Component I)
E8M85_RS04775	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E8M85_RS04785	ENOG4108PSN	Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity)
E8M85_RS04820	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
E8M85_RS04825	ENOG4105D7B	Flagellar biosynthesis protein flha
E8M85_RS04835	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
E8M85_RS04840	ENOG4105CNU	cell division protein FtsK
E8M85_RS04845	ENOG4105DTJ	flagellar hook-associated protein
E8M85_RS04860	ENOG4105C5H	ABC transporter
E8M85_RS04865	ENOG4105BZU	Histidine kinase
E8M85_RS04870	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8M85_RS04875	ENOG4108JQ1	Dehydrogenase
E8M85_RS04885	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E8M85_RS04890	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
E8M85_RS04895	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E8M85_RS04900	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E8M85_RS04905	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
E8M85_RS04910	ENOG4105K59	histidine triad (HIT) protein
E8M85_RS04925	ENOG4105E5Q	amino acid AbC transporter
E8M85_RS04940	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
E8M85_RS04945	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E8M85_RS04970	ENOG4108ZX6	Electron transport protein SCO1 SenC
E8M85_RS04975	ENOG4105C6T	cysteine synthase
E8M85_RS04980	ENOG410841J	DNA-binding protein Hu
E8M85_RS04990	ENOG4105NAU	thioesterase Superfamily protein
E8M85_RS05000	ENOG4105D22	carbon starvation protein
E8M85_RS05005	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E8M85_RS05010	ENOG4105DRP	amino acid AbC transporter
E8M85_RS05015	ENOG4105EAD	ABC transporter
E8M85_RS05020	ENOG4107RP9	extracellular solute-binding protein, family 3
E8M85_RS05025	ENOG4105CDA	abc transporter atp-binding protein
E8M85_RS05030	ENOG4105BZU	Histidine kinase
E8M85_RS05035	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E8M85_RS05060	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E8M85_RS05065	ENOG4105C3G	gtp-binding protein
E8M85_RS05070	ENOG4105CH7	arginosuccinase
E8M85_RS05075	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
E8M85_RS05080	ENOG4107QSA	Oxaloacetate decarboxylase
E8M85_RS05085	ENOG4105C8J	)-transporter
E8M85_RS05090	ENOG4105C8J	)-transporter
E8M85_RS05095	ENOG41084IH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E8M85_RS05155	ENOG4105EAD	ABC transporter
E8M85_RS05165	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E8M85_RS05170	ENOG4105ZGC	lipoprotein carrier protein
E8M85_RS05180	ENOG4107QUV	Domain protein
E8M85_RS05195	ENOG41076HS	cation diffusion facilitator family transporter
E8M85_RS05245	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E8M85_RS05250	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
E8M85_RS05270	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E8M85_RS05275	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
E8M85_RS05305	ENOG4107YD3	Thioesterase
E8M85_RS05330	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
E8M85_RS05345	ENOG4105KK6	nuclease
E8M85_RS05350	ENOG4105CIN	aminoacyl-histidine dipeptidase
E8M85_RS05355	ENOG4105CSH	Transporter
E8M85_RS05360	ENOG4105CT1	(ABC) transporter
E8M85_RS05365	ENOG4108F5X	surface-exposed lipoprotein
E8M85_RS05370	ENOG410802Z	Protein of unknown function (DUF328)
E8M85_RS05375	ENOG4105CH2	amidohydrolase
E8M85_RS05380	ENOG4105EKN	Major Facilitator
E8M85_RS05400	ENOG4105DF6	Fe-S oxidoreductase
E8M85_RS05405	ENOG4105D4P	Coproporphyrinogen iii oxidase
E8M85_RS05415	ENOG4105DBV	ornithine carbamoyltransferase
E8M85_RS05420	ENOG4105D52	delta-aminolevulinic acid dehydratase
E8M85_RS05425	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
E8M85_RS05430	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
E8M85_RS05440	ENOG4105HMI	Membrane
E8M85_RS05445	ENOG4105DUM	transcriptional regulator, lysR family
E8M85_RS05450	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8M85_RS05475	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E8M85_RS05495	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
E8M85_RS05515	ENOG4105CRE	cytochrome C
E8M85_RS05520	ENOG4108IV0	ABC, transporter
E8M85_RS05525	ENOG4105C0Z	ABC transporter
E8M85_RS05530	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
E8M85_RS05535	ENOG4105C32	Amino acid ABC transporter (Permease)
E8M85_RS05565	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E8M85_RS05585	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E8M85_RS05600	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
E8M85_RS05625	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
E8M85_RS05635	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E8M85_RS05640	ENOG4105CNI	cell division protein FtsW
E8M85_RS05645	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E8M85_RS05665	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E8M85_RS05670	ENOG4105D41	biosynthesis protein thiH
E8M85_RS05675	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
E8M85_RS05690	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
E8M85_RS05710	ENOG4105C98	muts2 protein
E8M85_RS05740	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E8M85_RS05755	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E8M85_RS05760	ENOG4105CEV	competence damage-inducible protein
E8M85_RS05775	ENOG4108RCM	Nitroreductase
E8M85_RS05785	ENOG4105DZP	Membrane-associated zinc metalloprotease
E8M85_RS05790	ENOG4108MJ5	VirK protein
E8M85_RS05800	ENOG4108UUM	single-stranded DNA-binding protein
E8M85_RS05805	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
E8M85_RS05810	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E8M85_RS05820	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
E8M85_RS05825	ENOG4105II7	pyrroline-5-carboxylate reductase
E8M85_RS05850	ENOG410820E	Thiamine monophosphate
E8M85_RS05855	ENOG4105DWF	phosphomethylpyrimidine kinase
E8M85_RS05870	ENOG4108JA2	transcriptioN-repair coupling factor
E8M85_RS05880	ENOG4105DR5	peptidase
E8M85_RS05885	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E8M85_RS05900	ENOG4105C8T	Leucyl-tRNA synthetase
E8M85_RS05905	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E8M85_RS05910	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E8M85_RS05915	ENOG4105VIE	preprotein translocase, subunit YajC
E8M85_RS05920	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E8M85_RS05925	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
E8M85_RS05930	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
E8M85_RS05935	ENOG4105CXT	aspartate transcarbamylase
E8M85_RS05940	ENOG4105DPN	Oligoendopeptidase f
E8M85_RS05950	ENOG4105C4R	Atp-dependent dna helicase
E8M85_RS05955	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E8M85_RS05970	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
E8M85_RS05985	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E8M85_RS05990	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E8M85_RS05995	ENOG4107SDU	Methyl-accepting chemotaxis
E8M85_RS06000	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
E8M85_RS06005	ENOG4105E0X	reductase
E8M85_RS06010	ENOG4105ED9	Protein of unknown function (DUF455)
E8M85_RS06015	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
E8M85_RS06025	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E8M85_RS06035	ENOG4108VYJ	response regulator receiver protein
E8M85_RS06045	ENOG4105C5E	polysaccharide biosynthesis protein
E8M85_RS06050	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E8M85_RS06060	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
E8M85_RS06065	ENOG4105D3Q	Sugar transferase
E8M85_RS06070	ENOG4105CGN	Glycosyl transferase (Group 1
E8M85_RS06075	ENOG4107ZAZ	Oligosaccharyl transferase, STT3 subunit
E8M85_RS06080	ENOG4105CG5	Glycosyl transferase (Group 1
E8M85_RS06085	ENOG4105K64	Glycosyl transferase, family 2
E8M85_RS06090	ENOG4105CG5	Glycosyl transferase (Group 1
E8M85_RS06095	ENOG4105BZ1	(ABC) transporter
E8M85_RS06100	ENOG4105CMR	udp-glucose 4-epimerase
E8M85_RS06110	ENOG4105D16	lipopolysaccharide heptosyltransferase i
E8M85_RS06115	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
E8M85_RS06120	ENOG4106WTF	Glycosyl transferase, family 2
E8M85_RS06145	ENOG4105I85	Bifunctional alpha-2,3 -2,8-sialyltransferase
E8M85_RS06150	ENOG4105D2T	synthase
E8M85_RS06155	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
E8M85_RS06175	ENOG4107QRS	glycosyltransferase group 2 family protein
E8M85_RS06185	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
E8M85_RS06190	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
E8M85_RS06195	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
E8M85_RS06200	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
E8M85_RS06215	ENOG4105C59	p-type ATPase
E8M85_RS06220	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E8M85_RS06225	ENOG4107QMP	dna polymerase iii subunits gamma and tau
E8M85_RS06240	ENOG4105C59	p-type ATPase
E8M85_RS06260	ENOG4107XM3	UPF0442 protein
E8M85_RS06275	ENOG4107T5V	SNARE associated Golgi
E8M85_RS06290	ENOG4108ZCU	PPIases accelerate the folding of proteins
E8M85_RS06300	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
E8M85_RS06315	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E8M85_RS06320	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E8M85_RS06330	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
E8M85_RS06335	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E8M85_RS06345	ENOG4105CE9	30S ribosomal protein S2
E8M85_RS06350	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
E8M85_RS06360	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E8M85_RS06365	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E8M85_RS06370	ENOG4108KUF	arsenical pump membrane protein
E8M85_RS06375	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
E8M85_RS06385	ENOG4107SDU	Methyl-accepting chemotaxis
E8M85_RS06395	ENOG4105CK2	sodium dicarboxylate symporter
E8M85_RS06420	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E8M85_RS06425	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
E8M85_RS06435	ENOG4105D01	(LipO)protein
E8M85_RS06445	ENOG4105SYT	Methylenetetrahydrofolate reductase
E8M85_RS06460	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E8M85_RS06465	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E8M85_RS06495	ENOG4107S2Z	UPF0761 membrane protein
E8M85_RS06500	ENOG4105CQB	FAD linked oxidase domain protein
E8M85_RS06510	ENOG4105DR5	peptidase
E8M85_RS06520	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E8M85_RS06535	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
E8M85_RS06540	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E8M85_RS06550	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E8M85_RS06580	ENOG4105C0H	protease
E8M85_RS06585	ENOG4105DVC	DnaJ domain protein
E8M85_RS06590	ENOG4105KNI	merR family transcriptional Regulator
E8M85_RS06595	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E8M85_RS06605	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
E8M85_RS06610	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
E8M85_RS06615	ENOG4105DR5	peptidase
E8M85_RS06630	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E8M85_RS06645	ENOG4105F27	Major Facilitator
E8M85_RS06660	ENOG41082XB	radical SAM domain protein
E8M85_RS06725	ENOG4105KJF	protein tyrosine phosphatase
E8M85_RS06730	ENOG4105YIC	Major outer membrane protein
E8M85_RS06735	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E8M85_RS06750	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E8M85_RS06755	ENOG4108USZ	hydrogenase
E8M85_RS06760	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
E8M85_RS06765	ENOG4105DPX	Hydrogenase, large subunit
E8M85_RS06770	ENOG4105E3S	small subunit
E8M85_RS06775	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
E8M85_RS06780	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E8M85_RS06790	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E8M85_RS06795	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E8M85_RS06800	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
E8M85_RS06805	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
E8M85_RS06820	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E8M85_RS06825	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E8M85_RS06835	ENOG4105C34	Pseudouridine synthase
E8M85_RS06840	ENOG4105CNI	cell division protein FtsW
E8M85_RS06855	ENOG4105CZN	Potassium uptake protein
E8M85_RS06865	ENOG4108XUR	Pfam:DUF178
E8M85_RS06870	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
E8M85_RS06875	ENOG4105C6K	Malic enzyme
E8M85_RS06890	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E8M85_RS06895	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E8M85_RS06900	ENOG4105DHP	deoxycytidine triphosphate deaminase
E8M85_RS06905	ENOG4105C5E	polysaccharide biosynthesis protein
E8M85_RS06910	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E8M85_RS06915	ENOG4105EQQ	protein containing aminopeptidase domain
E8M85_RS06950	ENOG4108P1X	synthase
E8M85_RS07000	ENOG4105F0R	Cytidylyltransferase
E8M85_RS07005	ENOG4107DKY	pseudaminic acid biosynthesis-associated protein PseG
E8M85_RS07010	ENOG4105VDT	-acetyltransferase
E8M85_RS07015	ENOG4105I2C	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
E8M85_RS07020	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
E8M85_RS07035	ENOG4108IAJ	Nad-dependent epimerase dehydratase
E8M85_RS07040	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E8M85_RS07070	ENOG4105D2T	synthase
E8M85_RS07075	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
E8M85_RS07090	ENOG4105F0R	Cytidylyltransferase
E8M85_RS07120	ENOG4105I03	Flagellin
E8M85_RS07125	ENOG4105I03	Flagellin
E8M85_RS07145	ENOG4108VAU	general secretion pathway protein G
E8M85_RS07150	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E8M85_RS07160	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
E8M85_RS07165	ENOG4105KNE	Phosphatidate cytidylyltransferase
E8M85_RS07185	ENOG4105HDD	phospholipase
E8M85_RS07190	ENOG4105DHS	permease protein
E8M85_RS07195	ENOG4105CM4	permease protein
E8M85_RS07200	ENOG4108IPW	abc transporter atp-binding protein
E8M85_RS07220	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
E8M85_RS07225	ENOG4105CUW	cytochrome C-TYPE protein
E8M85_RS07230	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
E8M85_RS07245	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
E8M85_RS07250	ENOG4105F4G	Membrane
E8M85_RS07255	ENOG4105C9Q	fumarate hydratase class II
E8M85_RS07265	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E8M85_RS07275	ENOG4105DVY	radical SAM domain protein
E8M85_RS07280	ENOG4105C7N	Xanthine uracil vitamin C permease
E8M85_RS07285	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E8M85_RS07305	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
E8M85_RS07310	ENOG4107RDB	Major Facilitator
E8M85_RS07325	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
E8M85_RS07330	ENOG4105EM7	Selenocysteine-specific translation elongation factor
E8M85_RS07335	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
E8M85_RS07345	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
E8M85_RS07360	ENOG4105CH6	catalase
E8M85_RS07370	ENOG4105WWK	YheO domain protein
E8M85_RS07375	ENOG4105KME	endoribonuclease L-psp
E8M85_RS07390	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
E8M85_RS07400	ENOG4107K9B	ferrous iron transport protein
E8M85_RS07405	ENOG4105CE1	Ferrous iron transport protein b
E8M85_RS07410	ENOG4105E3S	small subunit
E8M85_RS07415	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
E8M85_RS07420	ENOG4105CP7	Triose-phosphate isomerase
E8M85_RS07425	ENOG4105BZA	Phosphoglycerate kinase
E8M85_RS07430	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E8M85_RS07450	ENOG4107QKV	phosphomannomutase
E8M85_RS07455	ENOG4105X6C	Flagellar basal body-associated protein FliL
E8M85_RS07460	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
E8M85_RS07480	ENOG41084CK	capsule polysaccharide
E8M85_RS07490	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
E8M85_RS07495	ENOG4107Z36	nucleotidyl transferase
E8M85_RS07500	ENOG41082DT	Glutamine amido-transferase
E8M85_RS07505	ENOG4105P12	pyruvate phosphate dikinase
E8M85_RS07510	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E8M85_RS07570	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
E8M85_RS07605	ENOG4105C2X	Arabinose 5-phosphate isomerase
E8M85_RS07610	ENOG4107V1M	polysaccharide export protein
E8M85_RS07615	ENOG4105ECX	polysaccharide export
E8M85_RS07625	ENOG41090SZ	ABC-2 type transporter
E8M85_RS07680	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E8M85_RS07705	ENOG4105YKR	
E8M85_RS07730	ENOG4105EJ9	Membrane
E8M85_RS07735	ENOG4105D7Q	type ii secretion system
E8M85_RS07740	ENOG4107QHF	type ii secretion system protein e
E8M85_RS07770	ENOG4107XGZ	Hydrolase
E8M85_RS07775	ENOG4105CDV	Ompa motb domain protein
E8M85_RS07780	ENOG4108UJD	30S ribosomal protein S9
E8M85_RS07785	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
E8M85_RS07790	ENOG4105C4R	Atp-dependent dna helicase
E8M85_RS07795	ENOG4107RMM	double-strand break repair protein Addb
E8M85_RS07840	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8M85_RS07855	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E8M85_RS07875	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E8M85_RS07885	ENOG41066VF	YeeE YedE family protein
E8M85_RS07895	ENOG4105CK7	Sodium proline symporter
E8M85_RS07915	ENOG4107SDU	Methyl-accepting chemotaxis
E8M85_RS07925	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E8M85_RS07935	ENOG4105QAX	Iron-sulfur
E8M85_RS07970	ENOG4108ZEX	molybdopterin converting factor, subunit 2
E8M85_RS07980	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E8M85_RS07985	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
E8M85_RS07995	ENOG4105E9M	CRISPR-associated protein, Csn1 family
E8M85_RS08010	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
E8M85_RS08015	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
E8M85_RS08020	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
E8M85_RS08025	ENOG4108UR8	BAX protein
E8M85_RS08035	ENOG4108RMU	ferritin dps family protein
E8M85_RS08040	ENOG4107QP8	phosphohexose isomerase
E8M85_RS08045	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E8M85_RS08050	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E8M85_RS08055	ENOG41078M4	ABC transporter
E8M85_RS08060	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
E8M85_RS08065	ENOG4105C8W	ABC transporter
E8M85_RS08070	ENOG4105E7W	lamb ycsf family protein
E8M85_RS08075	ENOG4105P4J	Allophanate hydrolase, subunit 1
E8M85_RS08080	ENOG4107R7A	Allophanate hydrolase subunit 2
E8M85_RS08090	ENOG4105NF4	modulator of drug activity
E8M85_RS08095	ENOG4105KVH	Transcriptional regulator
E8M85_RS08105	ENOG4105DQ4	alcohol dehydrogenase
E8M85_RS08110	ENOG4105DZR	Type I site-specific deoxyribonuclease
E8M85_RS08130	ENOG4105CVR	type I restriction-modification system
E8M85_RS08140	ENOG4108RYK	Nad-dependent epimerase dehydratase
E8M85_RS08145	ENOG4105KVH	Transcriptional regulator
E8M85_RS08165	ENOG4105C8Q	Methyl-accepting chemotaxis
E8M85_RS08180	ENOG4105C8S	subunit m
E8M85_RS08185	ENOG4105D65	subunit l
E8M85_RS08190	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E8M85_RS08195	ENOG4105DF2	NADH dehydrogenase subunit j
E8M85_RS08200	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E8M85_RS08205	ENOG4108IB6	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
E8M85_RS08230	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E8M85_RS08240	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E8M85_RS08255	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E8M85_RS08270	ENOG4105CQB	FAD linked oxidase domain protein
E8M85_RS08280	ENOG4105IBP	Cyclic peptide transporter
E8M85_RS08285	ENOG4105CSH	Transporter
E8M85_RS08290	ENOG4108W8B	Beta-lactamase domain protein
E8M85_RS08295	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
E8M85_RS08300	ENOG41067V7	50S ribosomal protein L36
E8M85_RS08315	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E8M85_RS08320	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E8M85_RS08325	ENOG4108ZT0	50S ribosomal protein l17
E8M85_RS08335	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E8M85_RS08340	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
E8M85_RS08350	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
E8M85_RS08365	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E8M85_RS08370	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
E8M85_RS08375	ENOG4105D1F	ATP-binding protein
E8M85_RS08380	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
E8M85_RS08390	ENOG4107RIQ	Sulfate adenylate transferase
E8M85_RS08395	ENOG4108ZAI	phosphatidylglycerophosphatase a
E8M85_RS08400	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
E8M85_RS08405	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E8M85_RS08410	ENOG4108WHG	pyridoxamine 5'-phosphate
E8M85_RS08415	ENOG4105D05	Receptor
E8M85_RS08420	ENOG4105EHG	Permease protein
E8M85_RS08425	ENOG4105E0A	ABC, transporter
E8M85_RS08430	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
E8M85_RS08440	ENOG4105CSH	Transporter
E8M85_RS08445	ENOG4105CEN	a g-specific adenine glycosylase
E8M85_RS08485	ENOG4105EJQ	L-serine dehydratase
E8M85_RS08490	ENOG4105C44	Serine transporter
E8M85_RS08505	ENOG4105M8K	biopolymer transport protein
E8M85_RS08510	ENOG4105M15	transport protein ExbD
E8M85_RS08535	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
E8M85_RS08540	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
E8M85_RS08555	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E8M85_RS08570	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E8M85_RS08575	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
E8M85_RS08590	ENOG4105CV1	Transketolase (EC 2.2.1.1)
E8M85_RS08600	ENOG4105DHJ	ABC, transporter
E8M85_RS08610	ENOG4108SNX	Mammalian cell entry related domain protein
E8M85_RS08620	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E8M85_RS08625	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E8M85_RS08630	ENOG4108QBX	(LipO)protein
E8M85_RS08635	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E8M85_RS08640	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E8M85_RS08650	ENOG4107SJW	iron permease, FTR1
E8M85_RS08675	ENOG4105C19	ABC transporter
E8M85_RS08740	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E8M85_RS08745	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E8M85_RS08750	ENOG4105E63	Pfam:DUF178
E8M85_RS08755	ENOG4105VS8	Flagellar biosynthetic protein fliq
E8M85_RS08785	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E8M85_RS08790	ENOG4105BZN	citrate synthase
E8M85_RS08800	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
E8M85_RS08805	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E8M85_RS08815	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E8M85_RS08820	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
E8M85_RS08825	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E8M85_RS08830	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
E8M85_RS08835	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E8M85_RS08840	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E8M85_RS08845	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
E8M85_RS08850	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E8M85_RS08855	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
E8M85_RS08860	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
E8M85_RS08865	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
E8M85_RS08870	ENOG41084HJ	50s ribosomal protein l29
E8M85_RS08875	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E8M85_RS08880	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
E8M85_RS08890	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E8M85_RS08900	ENOG4105KZZ	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E8M85_RS08910	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
E8M85_RS08915	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
E8M85_RS08920	ENOG4105FE9	pseudouridine synthase
E8M85_RS08925	ENOG4105CN5	Metallo-Beta-Lactamase
E8M85_RS08930	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E8M85_RS08940	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
E8M85_RS08980	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E8M85_RS08985	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E8M85_RS08990	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E8M85_RS09010	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
E8M85_RS09020	ENOG4105CVG	Homoserine O-transsuccinylase
E8M85_RS09030	ENOG4105BZE	flagellar hook protein, FlgE
E8M85_RS09035	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)