locus-tag	class	description
CJ8421_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CJ8421_RS00010	COG0592	DNA-directed DNA polymerase activity
CJ8421_RS00015	COG0187	DNA topoisomerase II activity
CJ8421_RS00030	COG2056	Na+-H+ antiporter family
CJ8421_RS00035	COG0070	glutamate synthase
CJ8421_RS00035	COG0069	glutamate synthase activity
CJ8421_RS00035	COG0067	glutamate synthase
CJ8421_RS00045	COG0493	'glutamate synthase
CJ8421_RS00050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CJ8421_RS00060	COG1592	Rubrerythrin
CJ8421_RS00080	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CJ8421_RS00095	COG0840	transmembrane signaling receptor activity
CJ8421_RS00100	COG1858	cytochrome C peroxidase
CJ8421_RS00105	COG0179	Fumarylacetoacetate (FAA) hydrolase
CJ8421_RS00110	COG0564	pseudouridine synthase activity
CJ8421_RS00115	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CJ8421_RS00120	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CJ8421_RS00135	COG0504	CTP synthase activity
CJ8421_RS00145	COG0252	asparaginase activity
CJ8421_RS00185	COG2890	protein-(glutamine-N5) methyltransferase activity
CJ8421_RS00215	COG2814	Major facilitator Superfamily
CJ8421_RS00235	COG1217	gtp-binding protein TYPA
CJ8421_RS00250	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CJ8421_RS00285	COG0471	metal ion transport
CJ8421_RS00320	COG1776	CheC inhibitor of MCP methylation
CJ8421_RS00320	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CJ8421_RS00325	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CJ8421_RS00330	COG1191	sigma factor activity
CJ8421_RS00340	COG0455	bacterial-type flagellum organization
CJ8421_RS00345	COG1419	protein localization to endoplasmic reticulum
CJ8421_RS00350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CJ8421_RS00355	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CJ8421_RS00360	COG0402	S-adenosylhomocysteine deaminase activity
CJ8421_RS00365	COG0616	signal peptide processing
CJ8421_RS00395	COG1139	Iron-sulfur cluster binding protein
CJ8421_RS00400	COG0247	lactate metabolic process
CJ8421_RS00415	COG3021	interspecies interaction between organisms
CJ8421_RS00430	COG1271	oxidase subunit
CJ8421_RS00435	COG1294	oxidase, subunit
CJ8421_RS00445	COG1794	racemase activity, acting on amino acids and derivatives
CJ8421_RS00455	COG1027	Aspartate ammonia-lyase
CJ8421_RS00460	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CJ8421_RS00490	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CJ8421_RS00495	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CJ8421_RS00515	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CJ8421_RS00515	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CJ8421_RS00520	COG1192	Involved in chromosome partitioning
CJ8421_RS00525	COG1475	DNA binding
CJ8421_RS00540	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJ8421_RS00555	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CJ8421_RS00560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CJ8421_RS00565	COG0811	peptide transport
CJ8421_RS00570	COG0848	biopolymer transport protein
CJ8421_RS00585	COG2885	chlorophyll binding
CJ8421_RS00595	COG1047	Peptidyl-prolyl cis-trans
CJ8421_RS00600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CJ8421_RS00605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CJ8421_RS00610	COG0037	tRNA processing
CJ8421_RS00635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CJ8421_RS00645	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CJ8421_RS00655	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CJ8421_RS00665	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CJ8421_RS00680	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CJ8421_RS00690	COG0083	homoserine kinase activity
CJ8421_RS00700	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CJ8421_RS00715	COG1401	restriction endodeoxyribonuclease activity
CJ8421_RS00725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CJ8421_RS00730	COG1121	(ABC) transporter
CJ8421_RS00740	COG0840	transmembrane signaling receptor activity
CJ8421_RS00750	COG0492	ferredoxin-NADP+ reductase activity
CJ8421_RS00755	COG3118	belongs to the thioredoxin family
CJ8421_RS00760	COG0792	nuclease activity
CJ8421_RS00765	COG0460	homoserine dehydrogenase
CJ8421_RS00770	COG0436	Aminotransferase
CJ8421_RS00785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJ8421_RS00790	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CJ8421_RS00795	COG0254	rRNA binding
CJ8421_RS00800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CJ8421_RS00820	COG0602	queuosine metabolic process
CJ8421_RS00825	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CJ8421_RS00850	COG1971	Probably functions as a manganese efflux pump
CJ8421_RS00865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CJ8421_RS00885	COG3842	ATPase activity
CJ8421_RS00895	COG1840	ABC-type Fe3 transport system, periplasmic component
CJ8421_RS00915	COG0811	peptide transport
CJ8421_RS00920	COG0848	biopolymer transport protein
CJ8421_RS00930	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CJ8421_RS00935	COG1253	flavin adenine dinucleotide binding
CJ8421_RS00945	COG2824	Alkylphosphonate utilization operon protein PhnA
CJ8421_RS00950	COG0861	Integral membrane protein TerC family
CJ8421_RS00955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CJ8421_RS00960	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CJ8421_RS00960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CJ8421_RS00970	COG0606	chelatase, subunit chli
CJ8421_RS00975	COG0242	peptide deformylase activity
CJ8421_RS00985	COG0544	peptidyl-prolyl cis-trans isomerase activity
CJ8421_RS00990	COG0302	gtp cyclohydrolase
CJ8421_RS00995	COG1157	protein secretion by the type III secretion system
CJ8421_RS01000	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CJ8421_RS01005	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CJ8421_RS01010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CJ8421_RS01010	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CJ8421_RS01035	COG2851	Citrate transporter
CJ8421_RS01040	COG1297	OPT oligopeptide transporter protein
CJ8421_RS01045	COG1968	undecaprenyl-diphosphatase activity
CJ8421_RS01050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CJ8421_RS01055	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CJ8421_RS01090	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CJ8421_RS01100	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CJ8421_RS01105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJ8421_RS01110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CJ8421_RS01125	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CJ8421_RS01145	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CJ8421_RS01150	COG0670	Belongs to the BI1 family
CJ8421_RS01155	COG0288	reversible hydration of carbon dioxide
CJ8421_RS01160	COG0668	transmembrane transport
CJ8421_RS01185	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CJ8421_RS01190	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CJ8421_RS01215	COG0477	Major facilitator Superfamily
CJ8421_RS01225	COG0315	cyclic pyranopterin monophosphate synthase activity
CJ8421_RS01230	COG2921	Belongs to the UPF0250 family
CJ8421_RS01240	COG0708	Exodeoxyribonuclease III
CJ8421_RS01245	COG2194	sulfuric ester hydrolase activity
CJ8421_RS01250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CJ8421_RS01260	COG0418	dihydroorotase activity
CJ8421_RS01270	COG2226	methyltransferase
CJ8421_RS01285	COG0428	transporter
CJ8421_RS01305	COG0330	HflC and HflK could
CJ8421_RS01315	COG1942	4-Oxalocrotonate Tautomerase
CJ8421_RS01320	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CJ8421_RS01325	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CJ8421_RS01330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJ8421_RS01340	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CJ8421_RS01345	COG1077	Cell shape determining protein MreB Mrl
CJ8421_RS01355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CJ8421_RS01375	COG0835	chemotaxis
CJ8421_RS01380	COG0643	Histidine kinase
CJ8421_RS01380	COG2198	Histidine kinase
CJ8421_RS01380	COG0784	Response regulator, receiver
CJ8421_RS01385	COG0784	Response regulator, receiver
CJ8421_RS01385	COG0835	chemotaxis
CJ8421_RS01400	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJ8421_RS01435	COG0454	-acetyltransferase
CJ8421_RS01455	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CJ8421_RS01475	COG4106	trans-aconitate 2-methyltransferase activity
CJ8421_RS01490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CJ8421_RS01495	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CJ8421_RS01500	COG2076	Multidrug Resistance protein
CJ8421_RS01515	COG0193	aminoacyl-tRNA hydrolase activity
CJ8421_RS01525	COG0019	diaminopimelate decarboxylase activity
CJ8421_RS01540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CJ8421_RS01550	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CJ8421_RS01560	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CJ8421_RS01575	COG2226	methyltransferase
CJ8421_RS01580	COG1570	exodeoxyribonuclease VII activity
CJ8421_RS01585	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CJ8421_RS01590	COG0251	oxidation-reduction process
CJ8421_RS01605	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CJ8421_RS01625	COG0450	alkyl hydroperoxide reductase
CJ8421_RS01630	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CJ8421_RS01635	COG1360	Flagellar Motor Protein
CJ8421_RS01640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CJ8421_RS01660	COG1238	metal cluster binding
CJ8421_RS01680	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CJ8421_RS01685	COG0730	response to heat
CJ8421_RS01700	COG0512	Glutamine amidotransferase of anthranilate synthase
CJ8421_RS01700	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJ8421_RS01710	COG0133	tryptophan synthase activity
CJ8421_RS01725	COG1776	CheC inhibitor of MCP methylation
CJ8421_RS01725	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CJ8421_RS01740	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CJ8421_RS01745	COG0745	RESPONSE REGULATOR receiver
CJ8421_RS01765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CJ8421_RS01770	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CJ8421_RS01775	COG1981	membrane
CJ8421_RS01780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJ8421_RS01790	COG1538	Outer membrane efflux protein
CJ8421_RS01800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJ8421_RS01815	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CJ8421_RS01825	COG0754	glutathionylspermidine amidase activity
CJ8421_RS01830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJ8421_RS01850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJ8421_RS01855	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CJ8421_RS01860	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CJ8421_RS01880	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CJ8421_RS01910	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CJ8421_RS01925	COG0469	pyruvate kinase activity
CJ8421_RS01930	COG0579	oxidoreductase
CJ8421_RS01970	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CJ8421_RS01975	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CJ8421_RS01990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CJ8421_RS02010	COG1053	succinate dehydrogenase
CJ8421_RS02015	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CJ8421_RS02060	COG2353	YceI-like domain
CJ8421_RS02090	COG0488	(ABC) transporter
CJ8421_RS02105	COG1739	Uncharacterized protein family UPF0029
CJ8421_RS02145	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CJ8421_RS02165	COG1028	Short-chain dehydrogenase reductase Sdr
CJ8421_RS02175	COG1053	succinate dehydrogenase
CJ8421_RS02180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CJ8421_RS02185	COG2048	Heterodisulfide reductase, subunit B
CJ8421_RS02190	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CJ8421_RS02195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJ8421_RS02200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJ8421_RS02230	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CJ8421_RS02235	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CJ8421_RS02245	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CJ8421_RS02265	COG2121	Domain of unknown function (DUF374)
CJ8421_RS02280	COG0195	Participates in both transcription termination and antitermination
CJ8421_RS02290	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CJ8421_RS02295	COG0612	Peptidase, M16
CJ8421_RS02300	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CJ8421_RS02305	COG2346	COG2346, Truncated hemoglobins
CJ8421_RS02320	COG0765	amino acid transport
CJ8421_RS02350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CJ8421_RS02355	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CJ8421_RS02370	COG0250	Participates in transcription elongation, termination and antitermination
CJ8421_RS02375	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CJ8421_RS02380	COG0081	regulation of translation
CJ8421_RS02390	COG0222	ribosome binding
CJ8421_RS02405	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CJ8421_RS02410	COG0049	tRNA binding
CJ8421_RS02455	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CJ8421_RS02470	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CJ8421_RS02475	COG0673	inositol 2-dehydrogenase activity
CJ8421_RS02490	COG0424	maF-like protein
CJ8421_RS02500	COG0542	response to heat
CJ8421_RS02505	COG1937	Protein conserved in bacteria
CJ8421_RS02510	COG0793	Belongs to the peptidase S41A family
CJ8421_RS02515	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CJ8421_RS02520	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJ8421_RS02525	COG0047	phosphoribosylformylglycinamidine synthase activity
CJ8421_RS02535	COG0204	Acyl-transferase
CJ8421_RS02550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJ8421_RS02570	COG1677	Flagellar hook-basal body complex protein FliE
CJ8421_RS02575	COG1558	bacterial-type flagellum-dependent cell motility
CJ8421_RS02580	COG1815	bacterial-type flagellum-dependent cell motility
CJ8421_RS02600	COG0039	L-malate dehydrogenase activity
CJ8421_RS02610	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CJ8421_RS02620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CJ8421_RS02620	COG0674	pyruvate-flavodoxin oxidoreductase activity
CJ8421_RS02625	COG1013	pyruvate-flavodoxin oxidoreductase activity
CJ8421_RS02645	COG0142	geranyltranstransferase activity
CJ8421_RS02650	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CJ8421_RS02665	COG0181	hydroxymethylbilane synthase activity
CJ8421_RS02670	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CJ8421_RS02680	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CJ8421_RS02695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CJ8421_RS02725	COG1289	transmembrane transporter activity
CJ8421_RS02730	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CJ8421_RS02735	COG0492	ferredoxin-NADP+ reductase activity
CJ8421_RS02750	COG0305	Participates in initiation and elongation during chromosome replication
CJ8421_RS02795	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJ8421_RS02795	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJ8421_RS02800	COG1610	YqeY-like protein
CJ8421_RS02805	COG0028	Belongs to the TPP enzyme family
CJ8421_RS02810	COG0440	acetolactate synthase activity
CJ8421_RS02820	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CJ8421_RS02825	COG0805	protein transport
CJ8421_RS02835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJ8421_RS02840	COG0494	nUDIX hydrolase
CJ8421_RS02845	COG0527	aspartate kinase activity
CJ8421_RS02860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CJ8421_RS02880	COG0196	riboflavin kinase activity
CJ8421_RS02885	COG2890	protein-(glutamine-N5) methyltransferase activity
CJ8421_RS02900	COG2860	membrane
CJ8421_RS02910	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CJ8421_RS02915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJ8421_RS02920	COG0191	fructose-bisphosphate aldolase activity
CJ8421_RS02940	COG0733	neurotransmitter:sodium symporter activity
CJ8421_RS02945	COG2258	MOSC domain
CJ8421_RS02960	COG1473	amidohydrolase
CJ8421_RS02965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJ8421_RS02970	COG1136	(ABC) transporter
CJ8421_RS02970	COG0577	efflux transmembrane transporter activity
CJ8421_RS02975	COG1538	Outer membrane efflux protein
CJ8421_RS02990	COG1696	Membrane protein involved in D-alanine export
CJ8421_RS02995	COG1528	Iron-storage protein
CJ8421_RS03000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CJ8421_RS03005	COG0573	inorganic phosphate transmembrane transporter activity
CJ8421_RS03010	COG0581	inorganic phosphate transmembrane transporter activity
CJ8421_RS03025	COG0534	Mate efflux family protein
CJ8421_RS03040	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CJ8421_RS03050	COG0298	carbon dioxide binding
CJ8421_RS03055	COG0409	Hydrogenase expression formation protein
CJ8421_RS03060	COG0309	Hydrogenase expression formation protein (HypE)
CJ8421_RS03065	COG0375	protein maturation
CJ8421_RS03070	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CJ8421_RS03075	COG3421	Type III restriction
CJ8421_RS03085	COG0557	exoribonuclease II activity
CJ8421_RS03100	COG0758	DNA mediated transformation
CJ8421_RS03120	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CJ8421_RS03140	COG0497	DNA recombination
CJ8421_RS03150	COG0084	hydrolase, TatD family'
CJ8421_RS03155	COG0791	NLP P60 protein
CJ8421_RS03155	COG1388	LysM domain
CJ8421_RS03160	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CJ8421_RS03235	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CJ8421_RS03255	COG0137	argininosuccinate synthase activity
CJ8421_RS03260	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CJ8421_RS03265	COG0802	atpase or kinase
CJ8421_RS03270	COG1137	ATPase activity
CJ8421_RS03275	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CJ8421_RS03280	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CJ8421_RS03300	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CJ8421_RS03310	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CJ8421_RS03325	COG0556	nucleotide-excision repair
CJ8421_RS03345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CJ8421_RS03355	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CJ8421_RS03365	COG0280	phosphate acetyltransferase
CJ8421_RS03395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJ8421_RS03400	COG0849	cell division
CJ8421_RS03405	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CJ8421_RS03410	COG4786	Flagellar basal body rod
CJ8421_RS03415	COG4786	Flagellar basal body rod
CJ8421_RS03420	COG0174	glutamine synthetase
CJ8421_RS03430	COG0826	peptidase U32
CJ8421_RS03435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CJ8421_RS03445	COG0752	glycyl-tRNA synthetase alpha subunit
CJ8421_RS03450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CJ8421_RS03460	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CJ8421_RS03460	COG1519	Transferase
CJ8421_RS03465	COG0564	pseudouridine synthase activity
CJ8421_RS03470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CJ8421_RS03475	COG0228	four-way junction DNA binding
CJ8421_RS03480	COG1837	Belongs to the UPF0109 family
CJ8421_RS03485	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CJ8421_RS03490	COG0336	Belongs to the RNA methyltransferase TrmD family
CJ8421_RS03505	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CJ8421_RS03510	COG1393	Belongs to the ArsC family
CJ8421_RS03515	COG0587	DNA-directed DNA polymerase activity
CJ8421_RS03520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CJ8421_RS03535	COG2890	protein-(glutamine-N5) methyltransferase activity
CJ8421_RS03540	COG0501	Belongs to the peptidase M48B family
CJ8421_RS03550	COG0521	Mo-molybdopterin cofactor biosynthetic process
CJ8421_RS03555	COG0598	Magnesium transport protein CorA
CJ8421_RS03585	COG3842	ATPase activity
CJ8421_RS03675	COG0675	Transposase, IS605 OrfB family
CJ8421_RS03685	COG4771	TonB-dependent receptor
CJ8421_RS03690	COG1420	regulation of RNA biosynthetic process
CJ8421_RS03700	COG0443	Heat shock 70 kDa protein
CJ8421_RS03715	COG0436	Aminotransferase
CJ8421_RS03720	COG1045	serine acetyltransferase
CJ8421_RS03725	COG1166	arginine decarboxylase activity
CJ8421_RS03740	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CJ8421_RS03745	COG0163	prenyltransferase activity
CJ8421_RS03755	COG1464	Belongs to the NlpA lipoprotein family
CJ8421_RS03760	COG1464	Belongs to the NlpA lipoprotein family
CJ8421_RS03765	COG1464	Belongs to the NlpA lipoprotein family
CJ8421_RS03770	COG2011	ABC-type metal ion transport system permease component
CJ8421_RS03775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CJ8421_RS03790	COG0210	DNA helicase
CJ8421_RS03800	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CJ8421_RS03810	COG0437	4 iron, 4 sulfur cluster binding
CJ8421_RS03815	COG0348	domain, Protein
CJ8421_RS03820	COG3043	anaerobic respiration
CJ8421_RS03855	COG0788	formyltetrahydrofolate deformylase activity
CJ8421_RS03860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CJ8421_RS03870	COG0642	Histidine kinase
CJ8421_RS03885	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CJ8421_RS03900	COG1181	Belongs to the D-alanine--D-alanine ligase family
CJ8421_RS03905	COG0632	four-way junction helicase activity
CJ8421_RS03915	COG0728	peptidoglycan biosynthetic process
CJ8421_RS03920	COG0215	cysteine-tRNA ligase activity
CJ8421_RS03925	COG1132	(ABC) transporter
CJ8421_RS03930	COG0167	dihydroorotate dehydrogenase activity
CJ8421_RS03935	COG0612	Peptidase, M16
CJ8421_RS03940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJ8421_RS03945	COG1028	Short-chain dehydrogenase reductase Sdr
CJ8421_RS03960	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CJ8421_RS03970	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CJ8421_RS03975	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CJ8421_RS03995	COG3843	relaxase mobilization nuclease domain protein
CJ8421_RS04045	COG1338	Plays a role in the flagellum-specific transport system
CJ8421_RS04085	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CJ8421_RS04105	COG1757	Na H antiporter
CJ8421_RS04110	COG4221	oxidoreductase activity
CJ8421_RS04120	COG1049	propionate catabolic process, 2-methylcitrate cycle
CJ8421_RS04125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJ8421_RS04135	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJ8421_RS04135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJ8421_RS04145	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CJ8421_RS04175	COG1408	metallophosphoesterase
CJ8421_RS04180	COG0688	phosphatidylethanolamine metabolic process
CJ8421_RS04220	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CJ8421_RS04225	COG0681	Belongs to the peptidase S26 family
CJ8421_RS04230	COG0303	'Molybdopterin
CJ8421_RS04235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CJ8421_RS04250	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJ8421_RS04250	COG0512	Glutamine amidotransferase of anthranilate synthase
CJ8421_RS04255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CJ8421_RS04260	COG0582	viral genome integration into host DNA
CJ8421_RS04265	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CJ8421_RS04295	COG3258	Cytochrome c
CJ8421_RS04325	COG2404	hydrolase activity, acting on ester bonds
CJ8421_RS04330	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CJ8421_RS04335	COG1959	2 iron, 2 sulfur cluster binding
CJ8421_RS04340	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CJ8421_RS04345	COG1674	ftsk spoiiie
CJ8421_RS04345	COG1196	nuclear chromosome segregation
CJ8421_RS04350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CJ8421_RS04365	COG0488	(ABC) transporter
CJ8421_RS04370	COG5002	protein histidine kinase activity
CJ8421_RS04375	COG0745	RESPONSE REGULATOR receiver
CJ8421_RS04380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CJ8421_RS04390	COG1185	polyribonucleotide nucleotidyltransferase activity
CJ8421_RS04390	COG0539	negative regulation of cytoplasmic translation
CJ8421_RS04400	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CJ8421_RS04405	COG0072	phenylalanine-tRNA ligase activity
CJ8421_RS04405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJ8421_RS04410	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CJ8421_RS04415	COG0537	adenosine 5'-monophosphoramidase activity
CJ8421_RS04430	COG0765	amino acid transport
CJ8421_RS04440	COG1115	amino acid carrier protein
CJ8421_RS04445	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CJ8421_RS04450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CJ8421_RS04475	COG1999	signal sequence binding
CJ8421_RS04480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CJ8421_RS04485	COG0776	regulation of translation
CJ8421_RS04505	COG1966	Carbon starvation protein
CJ8421_RS04510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CJ8421_RS04515	COG0765	amino acid transport
CJ8421_RS04520	COG0765	amino acid transport
CJ8421_RS04525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJ8421_RS04530	COG1126	abc transporter atp-binding protein
CJ8421_RS04535	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CJ8421_RS04540	COG2201	protein-glutamate methylesterase activity
CJ8421_RS04565	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CJ8421_RS04570	COG0012	GTP binding
CJ8421_RS04580	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CJ8421_RS04585	COG5016	pyruvate
CJ8421_RS04585	COG0511	ligase activity, forming carbon-carbon bonds
CJ8421_RS04590	COG0733	neurotransmitter:sodium symporter activity
CJ8421_RS04595	COG0733	neurotransmitter:sodium symporter activity
CJ8421_RS04660	COG0765	amino acid transport
CJ8421_RS04675	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CJ8421_RS04685	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CJ8421_RS04700	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CJ8421_RS04715	COG0840	transmembrane signaling receptor activity
CJ8421_RS04730	COG0138	bifunctional purine biosynthesis protein purh
CJ8421_RS04735	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CJ8421_RS04745	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CJ8421_RS04755	COG0706	membrane insertase activity
CJ8421_RS04770	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CJ8421_RS04790	COG0824	Thioesterase
CJ8421_RS04865	COG2195	Cleaves the N-terminal amino acid of tripeptides
CJ8421_RS04870	COG0477	Major facilitator Superfamily
CJ8421_RS04875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJ8421_RS04885	COG3022	response to hydroperoxide
CJ8421_RS04890	COG1473	amidohydrolase
CJ8421_RS04895	COG2807	transmembrane transport
CJ8421_RS04915	COG2181	nitrate reductase activity
CJ8421_RS04915	COG0247	lactate metabolic process
CJ8421_RS04920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJ8421_RS04930	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CJ8421_RS04935	COG0113	porphobilinogen synthase activity
CJ8421_RS04940	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJ8421_RS04945	COG0357	Ribosomal RNA small subunit methyltransferase G
CJ8421_RS04955	COG2855	membrane
CJ8421_RS04960	COG0583	DNA-binding transcription factor activity
CJ8421_RS04965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CJ8421_RS04985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJ8421_RS04990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJ8421_RS05030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CJ8421_RS05030	COG1333	cytochrome c biogenesis protein
CJ8421_RS05055	COG0683	leucine binding
CJ8421_RS05080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CJ8421_RS05085	COG2204	response regulator
CJ8421_RS05100	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CJ8421_RS05140	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CJ8421_RS05150	COG0439	Biotin carboxylase
CJ8421_RS05155	COG0772	Belongs to the SEDS family
CJ8421_RS05160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CJ8421_RS05180	COG0352	thiamine-phosphate diphosphorylase activity
CJ8421_RS05185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CJ8421_RS05190	COG2022	thiamine diphosphate biosynthetic process
CJ8421_RS05205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJ8421_RS05225	COG1193	negative regulation of DNA recombination
CJ8421_RS05255	COG0516	GMP reductase activity
CJ8421_RS05255	COG0517	IMP dehydrogenase activity
CJ8421_RS05275	COG1546	Belongs to the CinA family
CJ8421_RS05275	COG1058	Belongs to the CinA family
CJ8421_RS05280	COG0456	acetyltransferase
CJ8421_RS05290	COG0778	Nitroreductase
CJ8421_RS05300	COG0750	zinc metalloprotease
CJ8421_RS05305	COG2990	Protein conserved in bacteria
CJ8421_RS05315	COG0629	single-stranded DNA binding
CJ8421_RS05320	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CJ8421_RS05325	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CJ8421_RS05335	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CJ8421_RS05340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CJ8421_RS05385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CJ8421_RS05395	COG0739	heme binding
CJ8421_RS05400	COG0285	dihydrofolate synthase activity
CJ8421_RS05415	COG0495	leucyl-tRNA aminoacylation
CJ8421_RS05420	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJ8421_RS05425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJ8421_RS05430	COG1862	Preprotein translocase
CJ8421_RS05435	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CJ8421_RS05440	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CJ8421_RS05445	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CJ8421_RS05465	COG0210	DNA helicase
CJ8421_RS05470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CJ8421_RS05495	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CJ8421_RS05500	COG0542	response to heat
CJ8421_RS05505	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CJ8421_RS05515	COG2095	MarC family integral membrane protein
CJ8421_RS05520	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJ8421_RS05525	COG2833	Protein of unknown function (DUF455)
CJ8421_RS05530	COG1183	phosphatidylcholine synthase activity
CJ8421_RS05540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJ8421_RS05550	COG0745	RESPONSE REGULATOR receiver
CJ8421_RS05560	COG1086	Polysaccharide biosynthesis protein
CJ8421_RS05565	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJ8421_RS05570	COG0110	maltose O-acetyltransferase activity
CJ8421_RS05575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJ8421_RS05580	COG0438	transferase activity, transferring glycosyl groups
CJ8421_RS05590	COG0438	transferase activity, transferring glycosyl groups
CJ8421_RS05595	COG1215	transferase activity, transferring glycosyl groups
CJ8421_RS05600	COG0438	transferase activity, transferring glycosyl groups
CJ8421_RS05605	COG1132	(ABC) transporter
CJ8421_RS05610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJ8421_RS05620	COG0859	PFAM glycosyl transferase family 9
CJ8421_RS05625	COG1560	Kdo2-lipid A biosynthetic process
CJ8421_RS05630	COG0463	Glycosyl transferase, family 2
CJ8421_RS05635	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CJ8421_RS05670	COG1215	transferase activity, transferring glycosyl groups
CJ8421_RS05705	COG1216	Glycosyl transferase, family 2
CJ8421_RS05715	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CJ8421_RS05730	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CJ8421_RS05745	COG2217	Heavy metal translocating P-type atpase
CJ8421_RS05750	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CJ8421_RS05755	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CJ8421_RS05765	COG2217	Heavy metal translocating P-type atpase
CJ8421_RS05785	COG3610	response to peptide
CJ8421_RS05795	COG0039	L-malate dehydrogenase activity
CJ8421_RS05800	COG0586	Pfam SNARE associated Golgi protein
CJ8421_RS05815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CJ8421_RS05820	COG0217	transcriptional regulatory protein
CJ8421_RS05835	COG0018	arginyl-trna synthetase
CJ8421_RS05840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJ8421_RS05845	COG0194	GDP metabolic process
CJ8421_RS05855	COG1684	flagellar biosynthetic protein fliR
CJ8421_RS05865	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CJ8421_RS05870	COG0052	Belongs to the universal ribosomal protein uS2 family
CJ8421_RS05875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CJ8421_RS05885	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CJ8421_RS05890	COG0723	plastoquinol--plastocyanin reductase activity
CJ8421_RS05895	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CJ8421_RS05900	COG0445	tRNA wobble uridine modification
CJ8421_RS05920	COG1301	dicarboxylic acid transport
CJ8421_RS05935	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CJ8421_RS05970	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CJ8421_RS05980	COG0356	it plays a direct role in the translocation of protons across the membrane
CJ8421_RS05985	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CJ8421_RS05990	COG0552	protein localization to endoplasmic reticulum
CJ8421_RS06005	COG1418	mRNA catabolic process
CJ8421_RS06020	COG1295	ribonuclease BN
CJ8421_RS06025	COG0277	FAD linked oxidase domain protein
CJ8421_RS06035	COG0739	heme binding
CJ8421_RS06045	COG1496	oxidoreductase activity
CJ8421_RS06060	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CJ8421_RS06070	COG0642	Histidine kinase
CJ8421_RS06075	COG0745	RESPONSE REGULATOR receiver
CJ8421_RS06095	COG0642	Histidine kinase
CJ8421_RS06100	COG0745	RESPONSE REGULATOR receiver
CJ8421_RS06105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJ8421_RS06110	COG0484	heat shock protein binding
CJ8421_RS06115	COG0789	Transcriptional regulator
CJ8421_RS06120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CJ8421_RS06120	COG0475	glutathione-regulated potassium exporter activity
CJ8421_RS06130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJ8421_RS06135	COG0751	glycine-tRNA ligase activity
CJ8421_RS06140	COG0739	heme binding
CJ8421_RS06150	COG0248	Ppx GppA phosphatase
CJ8421_RS06170	COG2814	Major facilitator Superfamily
CJ8421_RS06185	COG0731	radical SAM domain protein
CJ8421_RS06205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CJ8421_RS06205	COG0519	Catalyzes the synthesis of GMP from XMP
CJ8421_RS06230	COG1185	polyribonucleotide nucleotidyltransferase activity
CJ8421_RS06245	COG2814	Major facilitator Superfamily
CJ8421_RS06250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJ8421_RS06255	COG4773	Receptor
CJ8421_RS06260	COG0484	heat shock protein binding
CJ8421_RS06265	COG0745	RESPONSE REGULATOR receiver
CJ8421_RS06270	COG0642	Histidine kinase
CJ8421_RS06275	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CJ8421_RS06280	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CJ8421_RS06285	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CJ8421_RS06290	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CJ8421_RS06295	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CJ8421_RS06320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CJ8421_RS06325	COG1758	RNA polymerase activity
CJ8421_RS06330	COG0528	UMP kinase activity
CJ8421_RS06345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CJ8421_RS06350	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CJ8421_RS06360	COG0564	pseudouridine synthase activity
CJ8421_RS06365	COG0772	Belongs to the SEDS family
CJ8421_RS06380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CJ8421_RS06385	COG0569	domain protein
CJ8421_RS06390	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CJ8421_RS06395	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CJ8421_RS06400	COG0281	malic enzyme
CJ8421_RS06400	COG0280	phosphate acetyltransferase
CJ8421_RS06415	COG0439	Biotin carboxylase
CJ8421_RS06420	COG0511	ligase activity, forming carbon-carbon bonds
CJ8421_RS06430	COG1086	Polysaccharide biosynthesis protein
CJ8421_RS06435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJ8421_RS06470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJ8421_RS06510	COG1083	cytidylyl-transferase
CJ8421_RS06515	COG3980	spore coat polysaccharide biosynthesis protein
CJ8421_RS06520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJ8421_RS06525	COG0107	imidazoleglycerol-phosphate synthase activity
CJ8421_RS06540	COG2089	acid synthase
CJ8421_RS06550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJ8421_RS06555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJ8421_RS06590	COG2089	acid synthase
CJ8421_RS06595	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CJ8421_RS06600	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CJ8421_RS06610	COG1083	cytidylyl-transferase
CJ8421_RS06615	COG1028	Short-chain dehydrogenase reductase Sdr
CJ8421_RS06640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CJ8421_RS06645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CJ8421_RS06665	COG2165	general secretion pathway protein
CJ8421_RS06670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CJ8421_RS06685	COG0575	Belongs to the CDS family
CJ8421_RS06695	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CJ8421_RS06705	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CJ8421_RS06715	COG4605	iron ion homeostasis
CJ8421_RS06720	COG4604	ABC transporter, ATP-binding protein
CJ8421_RS06725	COG4607	ABC-type enterochelin transport system periplasmic component
CJ8421_RS06740	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CJ8421_RS06745	COG3005	denitrification pathway
CJ8421_RS06750	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CJ8421_RS06785	COG0628	permease
CJ8421_RS06790	COG0114	fumarate hydratase activity
CJ8421_RS06800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CJ8421_RS06810	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CJ8421_RS06815	COG2252	PERMEase
CJ8421_RS06825	COG2853	Lipoprotein
CJ8421_RS06845	COG2814	Major facilitator Superfamily
CJ8421_RS06860	COG3276	selenocysteine insertion sequence binding
CJ8421_RS06890	COG0753	catalase activity
CJ8421_RS06900	COG2964	Protein conserved in bacteria
CJ8421_RS06905	COG0251	oxidation-reduction process
CJ8421_RS06930	COG1918	ferrous iron import across plasma membrane
CJ8421_RS06935	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CJ8421_RS06940	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CJ8421_RS06945	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CJ8421_RS06960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CJ8421_RS06985	COG1580	Controls the rotational direction of flagella during chemotaxis
CJ8421_RS07000	COG2124	cytochrome p450
CJ8421_RS07020	COG0529	Catalyzes the synthesis of activated sulfate
CJ8421_RS07025	COG1213	nucleotidyl transferase
CJ8421_RS07030	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CJ8421_RS07035	COG3848	Pyruvate phosphate dikinase
CJ8421_RS07035	COG0574	Belongs to the PEP-utilizing enzyme family
CJ8421_RS07040	COG2226	methyltransferase
CJ8421_RS07060	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CJ8421_RS07080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJ8421_RS07110	COG1442	glycosyl transferase family 8
CJ8421_RS07110	COG1216	Glycosyl transferase, family 2
CJ8421_RS07115	COG1442	glycosyl transferase family 8
CJ8421_RS07125	COG3562	capsule polysaccharide
CJ8421_RS07130	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CJ8421_RS07130	COG0517	IMP dehydrogenase activity
CJ8421_RS07175	COG0037	tRNA processing
CJ8421_RS07185	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CJ8421_RS07200	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CJ8421_RS07225	COG3951	Flagellar rod assembly protein muramidase FlgJ
CJ8421_RS07250	COG0730	response to heat
CJ8421_RS07255	COG1459	type II secretion system
CJ8421_RS07260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CJ8421_RS07290	COG0546	phosphoglycolate phosphatase activity
CJ8421_RS07300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CJ8421_RS07305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CJ8421_RS07310	COG0210	DNA helicase
CJ8421_RS07315	COG2887	Belongs to the helicase family. UvrD subfamily
CJ8421_RS07360	COG0745	RESPONSE REGULATOR receiver
CJ8421_RS07375	COG0505	Belongs to the CarA family
CJ8421_RS07395	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CJ8421_RS07410	COG0425	Belongs to the sulfur carrier protein TusA family
CJ8421_RS07415	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJ8421_RS07425	COG0709	Synthesizes selenophosphate from selenide and ATP
CJ8421_RS07445	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CJ8421_RS07455	COG0437	4 iron, 4 sulfur cluster binding
CJ8421_RS07465	COG3383	formate dehydrogenase (NAD+) activity
CJ8421_RS07495	COG0314	molybdopterin synthase activity
CJ8421_RS07500	COG0303	'Molybdopterin
CJ8421_RS07505	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CJ8421_RS07515	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CJ8421_RS07540	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CJ8421_RS07555	COG2992	FlgJ-related protein
CJ8421_RS07565	COG0783	Belongs to the Dps family
CJ8421_RS07570	COG0166	Belongs to the GPI family
CJ8421_RS07580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJ8421_RS07585	COG3839	Belongs to the ABC transporter superfamily
CJ8421_RS07590	COG4662	Binding-protein-dependent transport system inner membrane component
CJ8421_RS07595	COG2998	abc-type tungstate transport system, permease component
CJ8421_RS07605	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CJ8421_RS07610	COG1984	allophanate hydrolase subunit 2
CJ8421_RS07620	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJ8421_RS07625	COG1733	regulation of RNA biosynthetic process
CJ8421_RS07635	COG1064	alcohol dehydrogenase
CJ8421_RS07675	COG2814	Major facilitator Superfamily
CJ8421_RS07695	COG0640	Transcriptional regulator
CJ8421_RS07705	COG0798	PFAM Bile acid sodium symporter
CJ8421_RS07730	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJ8421_RS07735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CJ8421_RS07745	COG0839	Belongs to the complex I subunit 6 family
CJ8421_RS07755	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CJ8421_RS07780	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJ8421_RS07790	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJ8421_RS07805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJ8421_RS07810	COG0601	transmembrane transport
CJ8421_RS07820	COG0277	FAD linked oxidase domain protein
CJ8421_RS07830	COG4615	Cyclic peptide transporter
CJ8421_RS07850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CJ8421_RS07855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CJ8421_RS07865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CJ8421_RS07875	COG0202	RNA polymerase activity
CJ8421_RS07880	COG0203	ribosomal protein L17
CJ8421_RS07895	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CJ8421_RS07895	COG0131	Imidazoleglycerol-phosphate dehydratase
CJ8421_RS07920	COG0140	phosphoribosyl-ATP diphosphatase activity
CJ8421_RS07920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CJ8421_RS07925	COG2171	N-acyltransferase activity
CJ8421_RS07930	COG0489	protein tyrosine kinase activity
CJ8421_RS07935	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CJ8421_RS07935	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CJ8421_RS07940	COG0745	RESPONSE REGULATOR receiver
CJ8421_RS07945	COG2046	Belongs to the sulfate adenylyltransferase family
CJ8421_RS07950	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CJ8421_RS07955	COG0268	Binds directly to 16S ribosomal RNA
CJ8421_RS07965	COG0748	coenzyme F420 binding
CJ8421_RS07970	COG4771	TonB-dependent receptor
CJ8421_RS07975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJ8421_RS07980	COG1120	ATPase activity
CJ8421_RS07985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJ8421_RS07995	COG0477	Major facilitator Superfamily
CJ8421_RS08000	COG1194	a g-specific adenine glycosylase
CJ8421_RS08030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJ8421_RS08030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJ8421_RS08040	COG1760	l-serine dehydratase
CJ8421_RS08045	COG0814	amino acid
CJ8421_RS08060	COG0811	peptide transport
CJ8421_RS08065	COG0848	biopolymer transport protein
CJ8421_RS08090	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CJ8421_RS08095	COG0571	ribonuclease III activity
CJ8421_RS08100	COG0328	RNA-DNA hybrid ribonuclease activity
CJ8421_RS08110	COG0358	DNA primase activity
CJ8421_RS08125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CJ8421_RS08130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CJ8421_RS08145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CJ8421_RS08150	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CJ8421_RS08155	COG1127	ABC transporter
CJ8421_RS08165	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CJ8421_RS08165	COG3218	ABC-type transport auxiliary lipoprotein component
CJ8421_RS08175	COG0024	Methionine aminopeptidase
CJ8421_RS08180	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CJ8421_RS08185	COG0791	NLP P60 protein
CJ8421_RS08195	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CJ8421_RS08205	COG0672	)-iron permease
CJ8421_RS08230	COG1136	(ABC) transporter
CJ8421_RS08360	COG1793	dna ligase
CJ8421_RS08375	COG0148	phosphopyruvate hydratase activity
CJ8421_RS08380	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CJ8421_RS08385	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CJ8421_RS08390	COG1987	bacterial-type flagellum assembly
CJ8421_RS08405	COG1218	3'(2'),5'-bisphosphate nucleotidase
CJ8421_RS08410	COG0372	Belongs to the citrate synthase family
CJ8421_RS08420	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CJ8421_RS08425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CJ8421_RS08435	COG0201	protein transport
CJ8421_RS08440	COG0200	Binds to the 23S rRNA
CJ8421_RS08445	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CJ8421_RS08455	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CJ8421_RS08460	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CJ8421_RS08465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CJ8421_RS08470	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CJ8421_RS08475	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CJ8421_RS08480	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CJ8421_RS08485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CJ8421_RS08490	COG0255	Belongs to the universal ribosomal protein uL29 family
CJ8421_RS08495	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CJ8421_RS08500	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CJ8421_RS08510	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CJ8421_RS08520	COG0089	rRNA binding
CJ8421_RS08530	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CJ8421_RS08535	COG0051	transcription antitermination factor activity, RNA binding
CJ8421_RS08540	COG1187	pseudouridine synthase activity
CJ8421_RS08545	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CJ8421_RS08600	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CJ8421_RS08610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CJ8421_RS08635	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CJ8421_RS08650	COG1749	Flagellar hook protein flgE