locus-tag	class	description
E8N02_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E8N02_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E8N02_RS00015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E8N02_RS00030	ENOG4105D3Y	Na H antiporter
E8N02_RS00045	ENOG4105BZ8	glutamate synthase
E8N02_RS00060	ENOG4108RAC	Rubrerythrin
E8N02_RS00065	ENOG4105C01	Dihydroxy-acid dehydratase
E8N02_RS00080	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
E8N02_RS00095	ENOG4108N3W	hemolysin secretion protein
E8N02_RS00100	ENOG4105CA0	peroxidase
E8N02_RS00105	ENOG4105ERH	Fumarylacetoacetate hydrolase
E8N02_RS00110	ENOG4105EI2	Pseudouridine synthase
E8N02_RS00115	ENOG4107QTF	adenylosuccinate lyase
E8N02_RS00120	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E8N02_RS00135	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
E8N02_RS00140	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E8N02_RS00145	ENOG4107RB3	L-asparaginase
E8N02_RS00195	ENOG4105C2C	drug resistance transporter, Bcr CflA
E8N02_RS00215	ENOG4105CI3	gtp-binding protein typa
E8N02_RS00230	ENOG410822I	Flagellar hook capping protein
E8N02_RS00235	ENOG4105BZE	flagellar hook protein, FlgE
E8N02_RS00260	ENOG4107QPK	)-transporter
E8N02_RS00270	ENOG4107QPK	)-transporter
E8N02_RS00280	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
E8N02_RS00310	ENOG4105DD5	Flagellar motor switch protein
E8N02_RS00315	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E8N02_RS00320	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8N02_RS00330	ENOG4107R21	site-determining protein
E8N02_RS00335	ENOG4105FZW	flagellar biosynthesis regulator FlhF
E8N02_RS00340	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E8N02_RS00345	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
E8N02_RS00350	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
E8N02_RS00355	ENOG4105D07	Signal peptide peptidase, SppA
E8N02_RS00380	ENOG4107QR9	Iron-sulfur cluster binding protein
E8N02_RS00385	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
E8N02_RS00390	ENOG4105DAA	L-lactate
E8N02_RS00400	ENOG4108TMH	cytolethal distending toxin
E8N02_RS00405	ENOG4106BMH	cytolethal distending toxin
E8N02_RS00415	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E8N02_RS00420	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E8N02_RS00435	ENOG4108IJ0	Aspartate ammonia-lyase
E8N02_RS00440	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
E8N02_RS00470	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
E8N02_RS00475	ENOG4105K46	50S ribosomal protein l27
E8N02_RS00495	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
E8N02_RS00500	ENOG4107QJE	Chromosome Partitioning Protein
E8N02_RS00505	ENOG4105FA0	parb-like partition protein
E8N02_RS00515	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
E8N02_RS00520	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E8N02_RS00535	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E8N02_RS00540	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
E8N02_RS00545	ENOG4105E02	MotA TolQ exbB proton channel
E8N02_RS00550	ENOG4105M8F	Biopolymer transport protein exbD tolR
E8N02_RS00565	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
E8N02_RS00575	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
E8N02_RS00580	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E8N02_RS00585	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
E8N02_RS00590	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
E8N02_RS00910	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E8N02_RS00920	ENOG4105SCY	DNAK suppressor
E8N02_RS00925	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
E8N02_RS00930	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
E8N02_RS00935	ENOG4105ECY	inositol monophosphatase
E8N02_RS00940	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E8N02_RS00965	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
E8N02_RS00985	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
E8N02_RS00990	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
E8N02_RS01015	ENOG4105C8Q	Methyl-accepting chemotaxis
E8N02_RS01025	ENOG4105C3M	thioredoxin reductase
E8N02_RS01030	ENOG4105K63	Thioredoxin
E8N02_RS01035	ENOG41082UM	UPF0102 protein
E8N02_RS01040	ENOG4105D6E	homoserine dehydrogenase
E8N02_RS01045	ENOG4105CHM	Aminotransferase
E8N02_RS01060	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E8N02_RS01070	ENOG41082DI	50s ribosomal protein l31
E8N02_RS01075	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E8N02_RS01095	ENOG4107XWN	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E8N02_RS01100	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E8N02_RS01125	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
E8N02_RS01140	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E8N02_RS01185	ENOG4105CWK	Biopolymer transport protein, ExbB
E8N02_RS01190	ENOG4108ZZF	transport protein (ExbD)
E8N02_RS01200	ENOG4108DQG	in Escherichia coli SbmA is involved in uptake of microcin J25
E8N02_RS01205	ENOG4105C37	(CBS) domain
E8N02_RS01215	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E8N02_RS01220	ENOG4105EE5	Membrane protein terC
E8N02_RS01225	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E8N02_RS01230	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E8N02_RS01240	ENOG4105C0P	Mg chelatase subunit ChlI
E8N02_RS01245	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E8N02_RS01255	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
E8N02_RS01265	ENOG4108JIR	Flagellum-specific ATP synthase
E8N02_RS01275	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
E8N02_RS01280	ENOG4105D1H	recombination factor protein RarA
E8N02_RS01310	ENOG4105EPD	Oligopeptide transporter, Opt family
E8N02_RS01315	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E8N02_RS01375	ENOG4105CAS	nag kinase
E8N02_RS01380	ENOG4105C8Y	Acetylornithine aminotransferase
E8N02_RS01385	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E8N02_RS01400	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E8N02_RS01420	ENOG4105NU9	Preprotein translocase subunit SecG
E8N02_RS01425	ENOG4105HFZ	Membrane
E8N02_RS01430	ENOG4107B2H	carbonic anhydrase
E8N02_RS01435	ENOG4105D64	Mechanosensitive ion channel
E8N02_RS01440	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
E8N02_RS01460	ENOG41084M8	50s ribosomal protein L35
E8N02_RS01465	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
E8N02_RS01485	ENOG4105CSH	Transporter
E8N02_RS01495	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E8N02_RS01500	ENOG41068HQ	Protein of unknown function (DUF493)
E8N02_RS01510	ENOG4105CGK	Exodeoxyribonuclease III
E8N02_RS01515	ENOG4105DIJ	Phosphoethanolamine transferase
E8N02_RS01520	ENOG41080IJ	Diacylglycerol kinase
E8N02_RS01530	ENOG4105EKE	dihydroorotase
E8N02_RS01540	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E8N02_RS01545	ENOG4105C8Q	Methyl-accepting chemotaxis
E8N02_RS01560	ENOG4105EPW	hflc protein
E8N02_RS01565	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E8N02_RS01570	ENOG4108F90	4-oxalocrotonate tautomerase
E8N02_RS01575	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E8N02_RS01580	ENOG4105WPN	DNA integration recombination invertion protein
E8N02_RS01595	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
E8N02_RS01610	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E8N02_RS01655	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E8N02_RS01660	ENOG4105D9P	serine threonine protein kinase
E8N02_RS01665	ENOG4107QMH	DNA methylase
E8N02_RS01695	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
E8N02_RS01715	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
E8N02_RS01720	ENOG4105E0C	molybdate abc transporter
E8N02_RS01730	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E8N02_RS01735	ENOG410825B	Type 11 methyltransferase
E8N02_RS01745	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E8N02_RS01750	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E8N02_RS01755	ENOG4107S77	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
E8N02_RS01760	ENOG41080TC	multidrug resistance protein
E8N02_RS01785	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E8N02_RS01795	ENOG4105CQC	Prephenate dehydratase
E8N02_RS01800	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E8N02_RS01805	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
E8N02_RS01810	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E8N02_RS01820	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E8N02_RS01835	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E8N02_RS01840	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E8N02_RS01845	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
E8N02_RS01850	ENOG4105M4H	endoribonuclease L-psp
E8N02_RS01865	ENOG4105YQ2	50s ribosomal protein l32
E8N02_RS01885	ENOG4105D3R	alkyl hydroperoxide reductase
E8N02_RS01890	ENOG4105D00	flagellar biosynthetic protein flhB
E8N02_RS01895	ENOG4108SEK	ompa motb domain protein
E8N02_RS01900	ENOG4105E14	MotA TolQ exbB proton channel
E8N02_RS01905	ENOG4105C2M	dna polymerase I
E8N02_RS01920	ENOG4105W39	Membrane
E8N02_RS01925	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E8N02_RS01945	ENOG4108EFP	Anthranilate synthase component II
E8N02_RS01955	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E8N02_RS01970	ENOG4105DD5	Flagellar motor switch protein
E8N02_RS01985	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E8N02_RS01990	ENOG4105ETX	regulatoR
E8N02_RS02005	ENOG4105CA0	peroxidase
E8N02_RS02010	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
E8N02_RS02015	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E8N02_RS02020	ENOG4108YXA	Membrane
E8N02_RS02025	ENOG4105CSA	Coproporphyrinogen iii oxidase
E8N02_RS02035	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E8N02_RS02045	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
E8N02_RS02060	ENOG41082DJ	30S ribosomal protein S21
E8N02_RS02065	ENOG4108UHV	Lipoprotein
E8N02_RS02070	ENOG4106032	Glutathionylspermidine synthase
E8N02_RS02075	ENOG4105C5I	Dehydrogenase
E8N02_RS02095	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E8N02_RS02100	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
E8N02_RS02105	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
E8N02_RS02125	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E8N02_RS02155	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
E8N02_RS02175	ENOG4107RSR	Malate quinone oxidoreductase
E8N02_RS02180	ENOG4108VHG	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
E8N02_RS02190	ENOG4108TX7	
E8N02_RS02215	ENOG4105CRK	lysyL-tRNA synthetase
E8N02_RS02235	ENOG4105E2X	shikimate dehydrogenase
E8N02_RS02250	ENOG4108S24	Fumarate reduCtase
E8N02_RS02255	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
E8N02_RS02260	ENOG4105E33	succinate dehydrogenase
E8N02_RS02270	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E8N02_RS02335	ENOG4105C5H	ABC transporter
E8N02_RS02350	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
E8N02_RS02390	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
E8N02_RS02405	ENOG4105CHR	reductase
E8N02_RS02415	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
E8N02_RS02420	ENOG4105E33	succinate dehydrogenase
E8N02_RS02425	ENOG41086B8	CoB-CoM heterodisulfide reductase
E8N02_RS02430	ENOG4105ETU	transcriptional activator (TenA
E8N02_RS02435	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E8N02_RS02440	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E8N02_RS02455	ENOG4107VIJ	nudix hydrolase
E8N02_RS02460	ENOG4107SDU	Methyl-accepting chemotaxis
E8N02_RS02470	ENOG4105VB9	50S ribosomal protein l28
E8N02_RS02475	ENOG4105DJV	ribulose-phosphate 3-epimerase
E8N02_RS02485	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
E8N02_RS02505	ENOG4105KB8	(LipO)protein
E8N02_RS02520	ENOG4105CHV	Transcription elongation factor NusA
E8N02_RS02530	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
E8N02_RS02540	ENOG4105CB5	ATP-dependent DNA helicase recG
E8N02_RS02545	ENOG4105VIG	Sec-independent protein translocase protein TatC
E8N02_RS02555	ENOG4105E5Q	amino acid AbC transporter
E8N02_RS02560	ENOG4105E5Q	amino acid AbC transporter
E8N02_RS02590	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E8N02_RS02610	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E8N02_RS02615	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
E8N02_RS02620	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E8N02_RS02630	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
E8N02_RS02645	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E8N02_RS02695	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
E8N02_RS02700	ENOG4105BZU	Histidine kinase
E8N02_RS02710	ENOG4105CK5	oxidoreductase
E8N02_RS02715	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E8N02_RS02725	ENOG4107YJQ	MAF-like protein
E8N02_RS02730	ENOG4108JQC	penicillin-binding protein 1A
E8N02_RS02735	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E8N02_RS02740	ENOG4105VPX	protein, conserved in bacteria
E8N02_RS02745	ENOG4105CN1	protease
E8N02_RS02755	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
E8N02_RS02760	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
E8N02_RS02770	ENOG4105E9Q	Acyl-transferase
E8N02_RS02785	ENOG4105MGE	Rhodanese domain protein
E8N02_RS02805	ENOG41084DA	flagellar hook-basal body complex protein fliE
E8N02_RS02810	ENOG4108ZC9	flagellar basal-body rod protein flgc
E8N02_RS02815	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
E8N02_RS02835	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
E8N02_RS02845	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E8N02_RS02855	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
E8N02_RS02860	ENOG4105DQU	oxidoreductase, subunit beta
E8N02_RS02880	ENOG4105EAH	synthase
E8N02_RS02885	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
E8N02_RS02900	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E8N02_RS02905	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
E8N02_RS02915	ENOG4107TPX	flagellar hook-associated
E8N02_RS02935	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E8N02_RS02965	ENOG4105ME7	Membrane
E8N02_RS02970	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
E8N02_RS02975	ENOG4105CAY	ferredoxin--nadp reductase
E8N02_RS02990	ENOG4105CDU	Replicative dna helicase
E8N02_RS03040	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E8N02_RS03045	ENOG4105KTH	gatB Yqey
E8N02_RS03050	ENOG4105C7K	acetolactate synthase
E8N02_RS03055	ENOG4108ZP8	Acetolactate synthase small subunit
E8N02_RS03070	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
E8N02_RS03080	ENOG4105CSA	Coproporphyrinogen iii oxidase
E8N02_RS03085	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E8N02_RS03090	ENOG4105CFH	Aspartokinase
E8N02_RS03105	ENOG4105EEI	dihydropteroate synthase
E8N02_RS03110	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E8N02_RS03125	ENOG4105DTN	riboflavin biosynthesis protein ribF
E8N02_RS03130	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
E8N02_RS03145	ENOG4105EN6	Membrane
E8N02_RS03155	ENOG4105CSM	endonuclease III
E8N02_RS03160	ENOG4105EIN	peptidylprolyl cis-trans isomerase
E8N02_RS03165	ENOG4105D2N	Aldolase
E8N02_RS03185	ENOG4105C8J	)-transporter
E8N02_RS03190	ENOG4108RPX	mosc domain containing protein
E8N02_RS03200	ENOG4105CSR	polyphosphate kinase 2
E8N02_RS03205	ENOG4105CH2	amidohydrolase
E8N02_RS03210	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E8N02_RS03215	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E8N02_RS03220	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E8N02_RS03235	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
E8N02_RS03240	ENOG41090A1	ferritin
E8N02_RS03250	ENOG4105C8U	phosphate abc transporter
E8N02_RS03255	ENOG4105E2Z	phosphate ABC transporter (Permease
E8N02_RS03270	ENOG4105UQX	Mate efflux family protein
E8N02_RS03295	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
E8N02_RS03300	ENOG4105CQS	hydrogenase expression formation protein HypD
E8N02_RS03305	ENOG4105C45	hydrogenase expression formation protein (HypE)
E8N02_RS03310	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
E8N02_RS03315	ENOG4107QMH	DNA methylase
E8N02_RS03320	ENOG4107J0C	type IIi
E8N02_RS03330	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E8N02_RS03335	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
E8N02_RS03345	ENOG4105C79	DNA protecting protein DprA
E8N02_RS03365	ENOG4105F0N	pyrophosphate phospho-hydrolase
E8N02_RS03375	ENOG4105C9M	aspartyl-trna synthetase
E8N02_RS03385	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E8N02_RS03395	ENOG4105F8V	Hydrolase, tatD family
E8N02_RS03405	ENOG4105K6T	rare lipoprotein A
E8N02_RS03445	ENOG4105DUX	Transporter
E8N02_RS03465	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
E8N02_RS03485	ENOG4105CDH	Citrulline--aspartate ligase
E8N02_RS03490	ENOG41082I2	s4 domain protein
E8N02_RS03500	ENOG4108IUZ	ABC transporter
E8N02_RS03505	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8N02_RS03510	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
E8N02_RS03525	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E8N02_RS03535	ENOG4105C08	Histidine kinase
E8N02_RS03560	ENOG4105C25	Primosomal protein n'
E8N02_RS03570	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
E8N02_RS03580	ENOG4105C6K	Malic enzyme
E8N02_RS03585	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E8N02_RS03615	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E8N02_RS03620	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E8N02_RS03625	ENOG4105KTQ	flagellar basal-body rod protein
E8N02_RS03630	ENOG4105CGA	flagellar basal-body rod protein FlgG
E8N02_RS03635	ENOG4105C5F	glutamine synthetase
E8N02_RS03645	ENOG4105CFP	Peptidase U32
E8N02_RS03660	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
E8N02_RS03665	ENOG4105EGD	dinuclear metal center protein, YbgI family
E8N02_RS03675	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
E8N02_RS03680	ENOG4105EI2	Pseudouridine synthase
E8N02_RS03685	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E8N02_RS03690	ENOG4105K5M	30s ribosomal protein S16
E8N02_RS03695	ENOG4105VB6	UPF0109 protein
E8N02_RS03700	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E8N02_RS03720	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
E8N02_RS03725	ENOG4105KUZ	arsenate reductase
E8N02_RS03735	ENOG4105C0B	DNA polymerase III (alpha subunit)
E8N02_RS03740	ENOG4105DFA	alanine racemase domain protein
E8N02_RS03755	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E8N02_RS03760	ENOG4105D0M	Protease HtpX homolog
E8N02_RS03770	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E8N02_RS03775	ENOG4105D7N	magnesium and cobalt transport protein CorA
E8N02_RS03795	ENOG4106SMU	thiamine transporter membrane protein
E8N02_RS03805	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8N02_RS03880	ENOG4105D7V	transposase
E8N02_RS03885	ENOG41067XB	TonB family
E8N02_RS03890	ENOG4105D05	Receptor
E8N02_RS03895	ENOG4108122	heat-inducible transcription repressor
E8N02_RS03900	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E8N02_RS03920	ENOG4105CHM	Aminotransferase
E8N02_RS03925	ENOG4105D7W	serine acetyltransferase
E8N02_RS03930	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
E8N02_RS03945	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
E8N02_RS03950	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
E8N02_RS03960	ENOG4105D01	(LipO)protein
E8N02_RS03965	ENOG4105D01	(LipO)protein
E8N02_RS03970	ENOG4105D01	(LipO)protein
E8N02_RS03975	ENOG4108UMI	ABC transporter, permease
E8N02_RS03980	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E8N02_RS03995	ENOG4105C4R	Atp-dependent dna helicase
E8N02_RS04005	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
E8N02_RS04015	ENOG4108BGM	Quinol dehydrogenase periplasmic component
E8N02_RS04020	ENOG4105GXZ	Ferredoxin-type protein NapH
E8N02_RS04025	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
E8N02_RS04060	ENOG4105CIY	formyltetrahydrofolate deformylase
E8N02_RS04085	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
E8N02_RS04100	ENOG4105CPF	Cell wall formation (By similarity)
E8N02_RS04105	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
E8N02_RS04115	ENOG4105CJR	Integral membrane protein (MviN
E8N02_RS04120	ENOG4105C8N	cysteinyl-tRNA synthetase
E8N02_RS04125	ENOG4105BZ1	(ABC) transporter
E8N02_RS04130	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E8N02_RS04140	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E8N02_RS04145	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
E8N02_RS04160	ENOG4105C4K	Nad synthetase
E8N02_RS04170	ENOG4107QID	Threonine synthase
E8N02_RS04175	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
E8N02_RS04185	ENOG4106PMH	Extracellular solute-binding protein family 3
E8N02_RS04190	ENOG4105CN7	Flagellar biosynthetic protein FliP
E8N02_RS04195	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E8N02_RS04225	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E8N02_RS04230	ENOG4105C7B	Threonine dehydratase
E8N02_RS04250	ENOG4107S6Z	Na H antiporter
E8N02_RS04255	ENOG4105EMU	Dehydrogenase
E8N02_RS04265	ENOG4107QIJ	Aconitate hydratase 2
E8N02_RS04270	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E8N02_RS04280	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E8N02_RS04290	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
E8N02_RS04320	ENOG4107RN3	metallophosphoesterase
E8N02_RS04325	ENOG4105DJ4	phosphatidylserine decarboxylase
E8N02_RS04330	ENOG4105D00	flagellar biosynthetic protein flhB
E8N02_RS04370	ENOG4105C3F	Signal peptidase i
E8N02_RS04375	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E8N02_RS04390	ENOG4105DDQ	anthranilate synthase
E8N02_RS04395	ENOG4105CRQ	synthase (Component I)
E8N02_RS04400	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E8N02_RS04410	ENOG4108PSN	Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity)
E8N02_RS04445	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
E8N02_RS04450	ENOG4105D7B	Flagellar biosynthesis protein flha
E8N02_RS04460	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
E8N02_RS04465	ENOG4105CNU	cell division protein FtsK
E8N02_RS04470	ENOG4105DTJ	flagellar hook-associated protein
E8N02_RS04485	ENOG4105C5H	ABC transporter
E8N02_RS04490	ENOG4105BZU	Histidine kinase
E8N02_RS04495	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8N02_RS04500	ENOG4108JQ1	Dehydrogenase
E8N02_RS04510	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E8N02_RS04515	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
E8N02_RS04520	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E8N02_RS04525	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E8N02_RS04530	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
E8N02_RS04535	ENOG4105K59	histidine triad (HIT) protein
E8N02_RS04550	ENOG4105E5Q	amino acid AbC transporter
E8N02_RS04570	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E8N02_RS04595	ENOG4108ZX6	Electron transport protein SCO1 SenC
E8N02_RS04600	ENOG4105C6T	cysteine synthase
E8N02_RS04605	ENOG410841J	DNA-binding protein Hu
E8N02_RS04615	ENOG4105NAU	thioesterase Superfamily protein
E8N02_RS04625	ENOG4105D22	carbon starvation protein
E8N02_RS04630	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E8N02_RS04635	ENOG4105DRP	amino acid AbC transporter
E8N02_RS04640	ENOG4105EAD	ABC transporter
E8N02_RS04645	ENOG4107RP9	extracellular solute-binding protein, family 3
E8N02_RS04650	ENOG4105CDA	abc transporter atp-binding protein
E8N02_RS04655	ENOG4105BZU	Histidine kinase
E8N02_RS04660	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E8N02_RS04685	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E8N02_RS04690	ENOG4105C3G	gtp-binding protein
E8N02_RS04700	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
E8N02_RS04705	ENOG4107QSA	Oxaloacetate decarboxylase
E8N02_RS04710	ENOG4105C8J	)-transporter
E8N02_RS04715	ENOG4105C8J	)-transporter
E8N02_RS04780	ENOG4105EAD	ABC transporter
E8N02_RS04790	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E8N02_RS04795	ENOG4105ZGC	lipoprotein carrier protein
E8N02_RS04805	ENOG4107QUV	Domain protein
E8N02_RS04820	ENOG41076HS	cation diffusion facilitator family transporter
E8N02_RS04840	ENOG4105C8Q	Methyl-accepting chemotaxis
E8N02_RS04850	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E8N02_RS04855	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
E8N02_RS04865	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E8N02_RS04875	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E8N02_RS04960	ENOG4105KK6	nuclease
E8N02_RS04965	ENOG4105CIN	aminoacyl-histidine dipeptidase
E8N02_RS04970	ENOG4105CSH	Transporter
E8N02_RS04975	ENOG4105CT1	(ABC) transporter
E8N02_RS04980	ENOG4108F5X	surface-exposed lipoprotein
E8N02_RS04985	ENOG410802Z	Protein of unknown function (DUF328)
E8N02_RS04990	ENOG4105CH2	amidohydrolase
E8N02_RS04995	ENOG4105EKN	Major Facilitator
E8N02_RS05005	ENOG4108F9G	
E8N02_RS05010	ENOG4105DF6	Fe-S oxidoreductase
E8N02_RS05015	ENOG4105D4P	Coproporphyrinogen iii oxidase
E8N02_RS05025	ENOG4105DBV	ornithine carbamoyltransferase
E8N02_RS05030	ENOG4105D52	delta-aminolevulinic acid dehydratase
E8N02_RS05035	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
E8N02_RS05040	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
E8N02_RS05050	ENOG4105HMI	Membrane
E8N02_RS05055	ENOG4105DUM	transcriptional regulator, lysR family
E8N02_RS05060	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8N02_RS05085	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E8N02_RS05325	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
E8N02_RS05330	ENOG4108WC9	type VI secretion system effector, hcp1 family
E8N02_RS05440	ENOG4105CS6	Rhs element vgr protein
E8N02_RS05510	ENOG4105CRE	cytochrome C
E8N02_RS05515	ENOG4108IV0	ABC, transporter
E8N02_RS05520	ENOG4105C0Z	ABC transporter
E8N02_RS05525	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
E8N02_RS05530	ENOG4105C32	Amino acid ABC transporter (Permease)
E8N02_RS05535	ENOG4105CP9	extracellular ligand-binding receptor
E8N02_RS05560	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E8N02_RS05580	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E8N02_RS05595	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
E8N02_RS05620	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
E8N02_RS05630	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E8N02_RS05635	ENOG4105CNI	cell division protein FtsW
E8N02_RS05640	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E8N02_RS05660	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E8N02_RS05665	ENOG4105D41	biosynthesis protein thiH
E8N02_RS05670	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
E8N02_RS05685	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
E8N02_RS05705	ENOG4105C98	muts2 protein
E8N02_RS05735	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E8N02_RS05755	ENOG4105CEV	competence damage-inducible protein
E8N02_RS05765	ENOG4108RCM	Nitroreductase
E8N02_RS05770	ENOG4108RCM	Nitroreductase
E8N02_RS05780	ENOG4105DZP	Membrane-associated zinc metalloprotease
E8N02_RS05785	ENOG4108MJ5	VirK protein
E8N02_RS05795	ENOG4108UUM	single-stranded DNA-binding protein
E8N02_RS05800	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
E8N02_RS05805	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E8N02_RS05815	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
E8N02_RS05820	ENOG4105II7	pyrroline-5-carboxylate reductase
E8N02_RS05850	ENOG4105DWF	phosphomethylpyrimidine kinase
E8N02_RS05865	ENOG4108JA2	transcriptioN-repair coupling factor
E8N02_RS05875	ENOG4105DR5	peptidase
E8N02_RS05880	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E8N02_RS05900	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E8N02_RS05905	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E8N02_RS05910	ENOG4105VIE	preprotein translocase, subunit YajC
E8N02_RS05915	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E8N02_RS05920	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
E8N02_RS05925	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
E8N02_RS05930	ENOG4105CXT	aspartate transcarbamylase
E8N02_RS05935	ENOG4105DPN	Oligoendopeptidase f
E8N02_RS05945	ENOG4105C4R	Atp-dependent dna helicase
E8N02_RS05980	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E8N02_RS05985	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E8N02_RS05990	ENOG4107SDU	Methyl-accepting chemotaxis
E8N02_RS05995	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
E8N02_RS06000	ENOG4105E0X	reductase
E8N02_RS06005	ENOG4105ED9	Protein of unknown function (DUF455)
E8N02_RS06010	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
E8N02_RS06020	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E8N02_RS06030	ENOG4108VYJ	response regulator receiver protein
E8N02_RS06040	ENOG4105C5E	polysaccharide biosynthesis protein
E8N02_RS06045	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E8N02_RS06050	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
E8N02_RS06055	ENOG4105D3Q	Sugar transferase
E8N02_RS06060	ENOG4105CGN	Glycosyl transferase (Group 1
E8N02_RS06070	ENOG4105CG5	Glycosyl transferase (Group 1
E8N02_RS06075	ENOG4105K64	Glycosyl transferase, family 2
E8N02_RS06080	ENOG4105CG5	Glycosyl transferase (Group 1
E8N02_RS06085	ENOG4105BZ1	(ABC) transporter
E8N02_RS06090	ENOG4105CMR	udp-glucose 4-epimerase
E8N02_RS06100	ENOG4105D16	lipopolysaccharide heptosyltransferase i
E8N02_RS06105	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
E8N02_RS06110	ENOG4106WTF	Glycosyl transferase, family 2
E8N02_RS06130	ENOG4105I85	Bifunctional alpha-2,3 -2,8-sialyltransferase
E8N02_RS06135	ENOG4105D2T	synthase
E8N02_RS06140	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
E8N02_RS06155	ENOG4105EQK	-acetyltransferase
E8N02_RS06160	ENOG4107QRS	glycosyltransferase group 2 family protein
E8N02_RS06180	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
E8N02_RS06185	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
E8N02_RS06200	ENOG4105C59	p-type ATPase
E8N02_RS06205	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E8N02_RS06210	ENOG4107QMP	dna polymerase iii subunits gamma and tau
E8N02_RS06225	ENOG4105C59	p-type ATPase
E8N02_RS06245	ENOG4107XM3	UPF0442 protein
E8N02_RS06255	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
E8N02_RS06260	ENOG4107T5V	SNARE associated Golgi
E8N02_RS06275	ENOG4108ZCU	PPIases accelerate the folding of proteins
E8N02_RS06280	ENOG4105CDY	transcriptional regulatory protein
E8N02_RS06285	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
E8N02_RS06295	ENOG4105C75	arginyL-tRNA synthetase
E8N02_RS06300	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E8N02_RS06305	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E8N02_RS06315	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
E8N02_RS06320	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E8N02_RS06325	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
E8N02_RS06330	ENOG4105CE9	30S ribosomal protein S2
E8N02_RS06335	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
E8N02_RS06345	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E8N02_RS06350	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E8N02_RS06355	ENOG4108KUF	arsenical pump membrane protein
E8N02_RS06370	ENOG4107SDU	Methyl-accepting chemotaxis
E8N02_RS06380	ENOG4105CK2	sodium dicarboxylate symporter
E8N02_RS06420	ENOG4105D01	(LipO)protein
E8N02_RS06430	ENOG4105SYT	Methylenetetrahydrofolate reductase
E8N02_RS06445	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E8N02_RS06450	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E8N02_RS06465	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
E8N02_RS06480	ENOG4107S2Z	UPF0761 membrane protein
E8N02_RS06485	ENOG4105CQB	FAD linked oxidase domain protein
E8N02_RS06495	ENOG4105DR5	peptidase
E8N02_RS06505	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E8N02_RS06520	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
E8N02_RS06525	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E8N02_RS06535	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E8N02_RS06565	ENOG4105C0H	protease
E8N02_RS06570	ENOG4105DVC	DnaJ domain protein
E8N02_RS06575	ENOG4105KNI	merR family transcriptional Regulator
E8N02_RS06580	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E8N02_RS06590	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
E8N02_RS06595	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
E8N02_RS06600	ENOG4105DR5	peptidase
E8N02_RS06630	ENOG4105F27	Major Facilitator
E8N02_RS06645	ENOG41082XB	radical SAM domain protein
E8N02_RS06665	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E8N02_RS06690	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
E8N02_RS06710	ENOG4105KJF	protein tyrosine phosphatase
E8N02_RS06715	ENOG4105YIC	Major outer membrane protein
E8N02_RS06720	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E8N02_RS06735	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E8N02_RS06740	ENOG4108USZ	hydrogenase
E8N02_RS06745	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
E8N02_RS06750	ENOG4105DPX	Hydrogenase, large subunit
E8N02_RS06755	ENOG4105E3S	small subunit
E8N02_RS06765	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E8N02_RS06780	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E8N02_RS06785	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
E8N02_RS06790	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
E8N02_RS06805	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E8N02_RS06820	ENOG4105C34	Pseudouridine synthase
E8N02_RS06825	ENOG4105CNI	cell division protein FtsW
E8N02_RS06840	ENOG4105CZN	Potassium uptake protein
E8N02_RS06850	ENOG4108XUR	Pfam:DUF178
E8N02_RS06860	ENOG4105C6K	Malic enzyme
E8N02_RS06875	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E8N02_RS06880	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E8N02_RS06890	ENOG4105C5E	polysaccharide biosynthesis protein
E8N02_RS06895	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E8N02_RS06935	ENOG4108P1X	synthase
E8N02_RS06985	ENOG4105F0R	Cytidylyltransferase
E8N02_RS06990	ENOG4107DKY	pseudaminic acid biosynthesis-associated protein PseG
E8N02_RS06995	ENOG4105VDT	-acetyltransferase
E8N02_RS07000	ENOG4105I2C	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
E8N02_RS07015	ENOG4105D2T	synthase
E8N02_RS07025	ENOG4108IAJ	Nad-dependent epimerase dehydratase
E8N02_RS07030	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E8N02_RS07045	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E8N02_RS07065	ENOG4105D2T	synthase
E8N02_RS07070	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
E8N02_RS07085	ENOG4105F0R	Cytidylyltransferase
E8N02_RS07115	ENOG4105I03	Flagellin
E8N02_RS07120	ENOG4105I03	Flagellin
E8N02_RS07140	ENOG4108VAU	general secretion pathway protein G
E8N02_RS07145	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E8N02_RS07160	ENOG4105KNE	Phosphatidate cytidylyltransferase
E8N02_RS07180	ENOG4105HDD	phospholipase
E8N02_RS07185	ENOG4105DHS	permease protein
E8N02_RS07190	ENOG4105CM4	permease protein
E8N02_RS07195	ENOG4108IPW	abc transporter atp-binding protein
E8N02_RS07215	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
E8N02_RS07220	ENOG4105CUW	cytochrome C-TYPE protein
E8N02_RS07250	ENOG4105F4G	Membrane
E8N02_RS07255	ENOG4105C9Q	fumarate hydratase class II
E8N02_RS07265	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E8N02_RS07275	ENOG4105DVY	radical SAM domain protein
E8N02_RS07280	ENOG4105C7N	Xanthine uracil vitamin C permease
E8N02_RS07285	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E8N02_RS07310	ENOG4107RDB	Major Facilitator
E8N02_RS07325	ENOG4105EM7	Selenocysteine-specific translation elongation factor
E8N02_RS07330	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
E8N02_RS07340	ENOG4108TGK	Low-potential electron donor to a number of redox enzymes (By similarity)
E8N02_RS07355	ENOG4105CH6	catalase
E8N02_RS07365	ENOG4105WWK	YheO domain protein
E8N02_RS07370	ENOG4105KME	endoribonuclease L-psp
E8N02_RS07405	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
E8N02_RS07415	ENOG4107K9B	ferrous iron transport protein
E8N02_RS07420	ENOG4105CE1	Ferrous iron transport protein b
E8N02_RS07425	ENOG4105E3S	small subunit
E8N02_RS07430	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
E8N02_RS07445	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E8N02_RS07465	ENOG4107QKV	phosphomannomutase
E8N02_RS07470	ENOG4105X6C	Flagellar basal body-associated protein FliL
E8N02_RS07495	ENOG41084CK	capsule polysaccharide
E8N02_RS07505	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
E8N02_RS07510	ENOG4107Z36	nucleotidyl transferase
E8N02_RS07515	ENOG41082DT	Glutamine amido-transferase
E8N02_RS07520	ENOG4105P12	pyruvate phosphate dikinase
E8N02_RS07525	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E8N02_RS07550	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
E8N02_RS07570	ENOG4105C30	Nad-dependent epimerase dehydratase
E8N02_RS07580	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
E8N02_RS07600	ENOG4105K64	Glycosyl transferase, family 2
E8N02_RS07620	ENOG4105K64	Glycosyl transferase, family 2
E8N02_RS07625	ENOG4105D5D	udp-galactopyranose mutase
E8N02_RS07645	ENOG4105C2X	Arabinose 5-phosphate isomerase
E8N02_RS07650	ENOG4107V1M	polysaccharide export protein
E8N02_RS07655	ENOG4105ECX	polysaccharide export
E8N02_RS07665	ENOG41090SZ	ABC-2 type transporter
E8N02_RS07700	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
E8N02_RS07715	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E8N02_RS07735	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E8N02_RS07740	ENOG4105YKR	
E8N02_RS07765	ENOG4105EJ9	Membrane
E8N02_RS07770	ENOG4105D7Q	type ii secretion system
E8N02_RS07775	ENOG4107QHF	type ii secretion system protein e
E8N02_RS07805	ENOG4107XGZ	Hydrolase
E8N02_RS07810	ENOG4105CDV	Ompa motb domain protein
E8N02_RS07815	ENOG4108UJD	30S ribosomal protein S9
E8N02_RS07820	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
E8N02_RS07825	ENOG4105C4R	Atp-dependent dna helicase
E8N02_RS07830	ENOG4107RMM	double-strand break repair protein Addb
E8N02_RS07875	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8N02_RS07890	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E8N02_RS07910	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E8N02_RS07920	ENOG41066VF	YeeE YedE family protein
E8N02_RS07930	ENOG4105CK7	Sodium proline symporter
E8N02_RS07950	ENOG4107SDU	Methyl-accepting chemotaxis
E8N02_RS07960	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E8N02_RS07970	ENOG4105QAX	Iron-sulfur
E8N02_RS08005	ENOG4108ZEX	molybdopterin converting factor, subunit 2
E8N02_RS08010	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E8N02_RS08015	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
E8N02_RS08040	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
E8N02_RS08055	ENOG4108UR8	BAX protein
E8N02_RS08065	ENOG4108RMU	ferritin dps family protein
E8N02_RS08070	ENOG4107QP8	phosphohexose isomerase
E8N02_RS08075	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E8N02_RS08080	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E8N02_RS08085	ENOG41078M4	ABC transporter
E8N02_RS08090	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
E8N02_RS08095	ENOG4105C8W	ABC transporter
E8N02_RS08100	ENOG4105E7W	lamb ycsf family protein
E8N02_RS08105	ENOG4105P4J	Allophanate hydrolase, subunit 1
E8N02_RS08110	ENOG4107R7A	Allophanate hydrolase subunit 2
E8N02_RS08120	ENOG4105NF4	modulator of drug activity
E8N02_RS08125	ENOG4105KVH	Transcriptional regulator
E8N02_RS08135	ENOG4105DQ4	alcohol dehydrogenase
E8N02_RS08140	ENOG4108F3G	Type I restriction-modification system, R subunit
E8N02_RS08150	ENOG41082EK	Restriction modification system DNA (Specificity
E8N02_RS08155	ENOG4107R3N	Filamentation induced by cAMP protein fic
E8N02_RS08180	ENOG4105F27	Major Facilitator
E8N02_RS08185	ENOG4108RYK	Nad-dependent epimerase dehydratase
E8N02_RS08190	ENOG4105KVH	Transcriptional regulator
E8N02_RS08200	ENOG41085FC	arsR family transcriptional regulator
E8N02_RS08210	ENOG4105C8Q	Methyl-accepting chemotaxis
E8N02_RS08225	ENOG4105C8S	subunit m
E8N02_RS08230	ENOG4105D65	subunit l
E8N02_RS08235	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E8N02_RS08250	ENOG4108IB6	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
E8N02_RS08275	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E8N02_RS08285	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E8N02_RS08300	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E8N02_RS08315	ENOG4105CQB	FAD linked oxidase domain protein
E8N02_RS08325	ENOG4105IBP	Cyclic peptide transporter
E8N02_RS08330	ENOG4105CSH	Transporter
E8N02_RS08345	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
E8N02_RS08350	ENOG41067V7	50S ribosomal protein L36
E8N02_RS08370	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E8N02_RS08375	ENOG4108ZT0	50S ribosomal protein l17
E8N02_RS08390	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
E8N02_RS08415	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E8N02_RS08420	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
E8N02_RS08425	ENOG4105D1F	ATP-binding protein
E8N02_RS08430	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
E8N02_RS08440	ENOG4107RIQ	Sulfate adenylate transferase
E8N02_RS08445	ENOG4108ZAI	phosphatidylglycerophosphatase a
E8N02_RS08450	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
E8N02_RS08460	ENOG4108WHG	pyridoxamine 5'-phosphate
E8N02_RS08465	ENOG4105D05	Receptor
E8N02_RS08470	ENOG4105EHG	Permease protein
E8N02_RS08475	ENOG4105E0A	ABC, transporter
E8N02_RS08480	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
E8N02_RS08495	ENOG4105CEN	a g-specific adenine glycosylase
E8N02_RS08535	ENOG4105EJQ	L-serine dehydratase
E8N02_RS08540	ENOG4105C44	Serine transporter
E8N02_RS08555	ENOG4105M8K	biopolymer transport protein
E8N02_RS08560	ENOG4105M15	transport protein ExbD
E8N02_RS08585	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
E8N02_RS08590	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
E8N02_RS08605	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E8N02_RS08620	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E8N02_RS08625	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
E8N02_RS08640	ENOG4105CV1	Transketolase (EC 2.2.1.1)
E8N02_RS08650	ENOG4105DHJ	ABC, transporter
E8N02_RS08660	ENOG4108SNX	Mammalian cell entry related domain protein
E8N02_RS08670	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E8N02_RS08675	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E8N02_RS08680	ENOG4108QBX	(LipO)protein
E8N02_RS08690	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E8N02_RS08700	ENOG4107SJW	iron permease, FTR1
E8N02_RS08725	ENOG4105C19	ABC transporter
E8N02_RS08790	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E8N02_RS08795	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E8N02_RS08800	ENOG4105E63	Pfam:DUF178
E8N02_RS08805	ENOG4105VS8	Flagellar biosynthetic protein fliq
E8N02_RS08820	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E8N02_RS08825	ENOG4105BZN	citrate synthase
E8N02_RS08835	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
E8N02_RS08840	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E8N02_RS08850	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E8N02_RS08855	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
E8N02_RS08860	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E8N02_RS08865	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
E8N02_RS08870	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E8N02_RS08875	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E8N02_RS08880	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
E8N02_RS08885	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E8N02_RS08890	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
E8N02_RS08895	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
E8N02_RS08900	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
E8N02_RS08905	ENOG41084HJ	50s ribosomal protein l29
E8N02_RS08910	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E8N02_RS08915	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
E8N02_RS08925	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E8N02_RS08935	ENOG4105KZZ	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E8N02_RS08945	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
E8N02_RS08950	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
E8N02_RS08955	ENOG4105FE9	pseudouridine synthase
E8N02_RS08960	ENOG4105CN5	Metallo-Beta-Lactamase
E8N02_RS09015	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E8N02_RS09040	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
E8N02_RS09050	ENOG4105CVG	Homoserine O-transsuccinylase
E8N02_RS09060	ENOG4105BZE	flagellar hook protein, FlgE
E8N02_RS09065	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)