locus-tag	class	description
CLA_RS00015	COG0592	DNA-directed DNA polymerase activity
CLA_RS00020	COG0187	DNA topoisomerase II activity
CLA_RS00025	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CLA_RS00035	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CLA_RS00055	COG2824	Alkylphosphonate utilization operon protein PhnA
CLA_RS00070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CLA_RS00080	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLA_RS00085	COG0268	Binds directly to 16S ribosomal RNA
CLA_RS00090	COG1187	pseudouridine synthase activity
CLA_RS00095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLA_RS00110	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CLA_RS00120	COG0564	pseudouridine synthase activity
CLA_RS00125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CLA_RS00130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLA_RS00135	COG1297	OPT oligopeptide transporter protein
CLA_RS00140	COG1968	undecaprenyl-diphosphatase activity
CLA_RS00145	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLA_RS00150	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CLA_RS00160	COG2378	regulation of single-species biofilm formation
CLA_RS00170	COG0714	Associated with various cellular activities
CLA_RS00175	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CLA_RS00180	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CLA_RS00185	COG1793	dna ligase
CLA_RS00190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLA_RS00195	COG1121	(ABC) transporter
CLA_RS00210	COG0418	dihydroorotase activity
CLA_RS00225	COG2194	sulfuric ester hydrolase activity
CLA_RS00230	COG0708	Exodeoxyribonuclease III
CLA_RS00245	COG1328	CTP reductase activity
CLA_RS00250	COG0602	queuosine metabolic process
CLA_RS00255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CLA_RS00260	COG3069	C4-dicarboxylate transmembrane transporter activity
CLA_RS00265	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CLA_RS00275	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CLA_RS00280	COG2992	FlgJ-related protein
CLA_RS00295	COG0051	transcription antitermination factor activity, RNA binding
CLA_RS00300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CLA_RS00305	COG0088	Forms part of the polypeptide exit tunnel
CLA_RS00310	COG0089	rRNA binding
CLA_RS00315	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLA_RS00320	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLA_RS00325	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CLA_RS00330	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CLA_RS00335	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLA_RS00340	COG0255	Belongs to the universal ribosomal protein uL29 family
CLA_RS00345	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CLA_RS00350	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CLA_RS00355	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CLA_RS00360	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CLA_RS00365	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CLA_RS00370	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CLA_RS00375	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLA_RS00380	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CLA_RS00385	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CLA_RS00390	COG0200	Binds to the 23S rRNA
CLA_RS00395	COG0201	protein transport
CLA_RS00400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CLA_RS00405	COG0252	asparaginase activity
CLA_RS00410	COG1592	Rubrerythrin
CLA_RS00425	COG0814	amino acid
CLA_RS00430	COG1760	l-serine dehydratase
CLA_RS00435	COG0024	Methionine aminopeptidase
CLA_RS00440	COG0840	transmembrane signaling receptor activity
CLA_RS00445	COG1858	cytochrome C peroxidase
CLA_RS00450	COG0477	Major facilitator Superfamily
CLA_RS00460	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CLA_RS00465	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CLA_RS00470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CLA_RS00480	COG0203	ribosomal protein L17
CLA_RS00485	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CLA_RS00495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CLA_RS00495	COG0131	Imidazoleglycerol-phosphate dehydratase
CLA_RS00515	COG0107	imidazoleglycerol-phosphate synthase activity
CLA_RS00520	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CLA_RS00520	COG0140	phosphoribosyl-ATP diphosphatase activity
CLA_RS00525	COG0840	transmembrane signaling receptor activity
CLA_RS00535	COG1749	Flagellar hook protein flgE
CLA_RS00545	COG2814	Major facilitator Superfamily
CLA_RS00550	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CLA_RS00560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLA_RS00565	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CLA_RS00585	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CLA_RS00630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CLA_RS00640	COG0745	RESPONSE REGULATOR receiver
CLA_RS00655	COG1194	a g-specific adenine glycosylase
CLA_RS00685	COG0569	domain protein
CLA_RS00690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CLA_RS00695	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CLA_RS00700	COG1027	Aspartate ammonia-lyase
CLA_RS00705	COG0840	transmembrane signaling receptor activity
CLA_RS00720	COG2921	Belongs to the UPF0250 family
CLA_RS00725	COG0315	cyclic pyranopterin monophosphate synthase activity
CLA_RS00745	COG2346	COG2346, Truncated hemoglobins
CLA_RS00760	COG0148	phosphopyruvate hydratase activity
CLA_RS00765	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLA_RS00775	COG1987	bacterial-type flagellum assembly
CLA_RS00790	COG1218	3'(2'),5'-bisphosphate nucleotidase
CLA_RS00795	COG0475	glutathione-regulated potassium exporter activity
CLA_RS00795	COG0569	domain protein
CLA_RS00800	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CLA_RS00805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLA_RS00845	COG2089	acid synthase
CLA_RS00855	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLA_RS00855	COG1776	CheC inhibitor of MCP methylation
CLA_RS00865	COG0248	Ppx GppA phosphatase
CLA_RS00870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLA_RS00875	COG0745	RESPONSE REGULATOR receiver
CLA_RS00885	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CLA_RS00915	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CLA_RS00920	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CLA_RS00925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLA_RS00930	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLA_RS00935	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CLA_RS00935	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CLA_RS00940	COG1192	Involved in chromosome partitioning
CLA_RS00945	COG1475	DNA binding
CLA_RS00960	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLA_RS00965	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLA_RS00970	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLA_RS00975	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CLA_RS00980	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CLA_RS00985	COG0811	peptide transport
CLA_RS00990	COG0848	biopolymer transport protein
CLA_RS01005	COG2885	chlorophyll binding
CLA_RS01020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CLA_RS01025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CLA_RS01030	COG0037	tRNA processing
CLA_RS01050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLA_RS01065	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CLA_RS01070	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CLA_RS01075	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLA_RS01080	COG0287	Prephenate dehydrogenase
CLA_RS01090	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CLA_RS01100	COG0083	homoserine kinase activity
CLA_RS01110	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CLA_RS01120	COG0779	Required for maturation of 30S ribosomal subunits
CLA_RS01135	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLA_RS01135	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLA_RS01140	COG0616	signal peptide processing
CLA_RS01145	COG0402	S-adenosylhomocysteine deaminase activity
CLA_RS01150	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CLA_RS01155	COG0006	proline dipeptidase activity
CLA_RS01160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLA_RS01165	COG1419	protein localization to endoplasmic reticulum
CLA_RS01170	COG0455	bacterial-type flagellum organization
CLA_RS01180	COG1191	sigma factor activity
CLA_RS01185	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLA_RS01190	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLA_RS01190	COG1776	CheC inhibitor of MCP methylation
CLA_RS01195	COG1611	Belongs to the LOG family
CLA_RS01200	COG0482	sulfurtransferase activity
CLA_RS01210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CLA_RS01215	COG2046	Belongs to the sulfate adenylyltransferase family
CLA_RS01220	COG0745	RESPONSE REGULATOR receiver
CLA_RS01225	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CLA_RS01225	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CLA_RS01230	COG0489	protein tyrosine kinase activity
CLA_RS01235	COG2171	N-acyltransferase activity
CLA_RS01240	COG0783	Belongs to the Dps family
CLA_RS01245	COG0166	Belongs to the GPI family
CLA_RS01255	COG1739	Uncharacterized protein family UPF0029
CLA_RS01270	COG0488	(ABC) transporter
CLA_RS01280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLA_RS01295	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CLA_RS01320	COG2855	membrane
CLA_RS01325	COG0583	DNA-binding transcription factor activity
CLA_RS01335	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLA_RS01350	COG0736	holo-[acyl-carrier-protein] synthase activity
CLA_RS01355	COG1580	Controls the rotational direction of flagella during chemotaxis
CLA_RS01365	COG0753	catalase activity
CLA_RS01375	COG0165	Argininosuccinate lyase
CLA_RS01385	COG0251	oxidation-reduction process
CLA_RS01390	COG3069	C4-dicarboxylate transmembrane transporter activity
CLA_RS01405	COG2079	MmgE PrpD family protein
CLA_RS01410	COG1918	ferrous iron import across plasma membrane
CLA_RS01415	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CLA_RS01420	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CLA_RS01425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLA_RS01430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLA_RS01435	COG0825	malonyl-CoA metabolic process
CLA_RS01465	COG0517	IMP dehydrogenase activity
CLA_RS01465	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CLA_RS01515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLA_RS01560	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CLA_RS01565	COG3848	Pyruvate phosphate dikinase
CLA_RS01565	COG0574	Belongs to the PEP-utilizing enzyme family
CLA_RS01570	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CLA_RS01575	COG1213	nucleotidyl transferase
CLA_RS01580	COG0529	Catalyzes the synthesis of activated sulfate
CLA_RS01615	COG0195	Participates in both transcription termination and antitermination
CLA_RS01630	COG2121	Domain of unknown function (DUF374)
CLA_RS01655	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CLA_RS01665	COG1053	succinate dehydrogenase
CLA_RS01670	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CLA_RS01690	COG0748	coenzyme F420 binding
CLA_RS01695	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLA_RS01700	COG1733	regulation of RNA biosynthetic process
CLA_RS01710	COG1064	alcohol dehydrogenase
CLA_RS01730	COG0732	type I restriction modification DNA specificity domain
CLA_RS01745	COG0303	'Molybdopterin
CLA_RS01750	COG0314	molybdopterin synthase activity
CLA_RS01785	COG0243	molybdopterin cofactor binding
CLA_RS01790	COG3383	formate dehydrogenase (NAD+) activity
CLA_RS01795	COG0437	4 iron, 4 sulfur cluster binding
CLA_RS01805	COG0425	Belongs to the sulfur carrier protein TusA family
CLA_RS01810	COG0709	Synthesizes selenophosphate from selenide and ATP
CLA_RS01820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLA_RS01825	COG0425	Belongs to the sulfur carrier protein TusA family
CLA_RS01840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLA_RS01860	COG0505	Belongs to the CarA family
CLA_RS01910	COG1074	ATP-dependent DNA helicase activity
CLA_RS01915	COG0840	transmembrane signaling receptor activity
CLA_RS01920	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CLA_RS01925	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CLA_RS01930	COG2885	chlorophyll binding
CLA_RS01930	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CLA_RS01935	COG0546	phosphoglycolate phosphatase activity
CLA_RS01960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLA_RS01965	COG1459	type II secretion system
CLA_RS01995	COG3951	Flagellar rod assembly protein muramidase FlgJ
CLA_RS02000	COG1706	bacterial-type flagellum-dependent cell motility
CLA_RS02025	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CLA_RS02045	COG0716	FMN binding
CLA_RS02070	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CLA_RS02080	COG0126	phosphoglycerate kinase activity
CLA_RS02085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CLA_RS02120	COG0114	fumarate hydratase activity
CLA_RS02125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CLA_RS02135	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CLA_RS02140	COG2252	PERMEase
CLA_RS02150	COG0243	molybdopterin cofactor binding
CLA_RS02170	COG4773	Receptor
CLA_RS02175	COG3022	response to hydroperoxide
CLA_RS02200	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLA_RS02205	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CLA_RS02220	COG0250	Participates in transcription elongation, termination and antitermination
CLA_RS02225	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CLA_RS02230	COG0081	regulation of translation
CLA_RS02235	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CLA_RS02240	COG0222	ribosome binding
CLA_RS02245	COG0085	RNA polymerase activity
CLA_RS02250	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLA_RS02255	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CLA_RS02260	COG0049	tRNA binding
CLA_RS02265	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLA_RS02270	COG1253	flavin adenine dinucleotide binding
CLA_RS02275	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CLA_RS02280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLA_RS02330	COG0848	biopolymer transport protein
CLA_RS02335	COG0811	peptide transport
CLA_RS02340	COG4771	TonB-dependent receptor
CLA_RS02350	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CLA_RS02355	COG2217	Heavy metal translocating P-type atpase
CLA_RS02370	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CLA_RS02375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLA_RS02380	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CLA_RS02380	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CLA_RS02385	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CLA_RS02390	COG0469	pyruvate kinase activity
CLA_RS02395	COG0579	oxidoreductase
CLA_RS02420	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLA_RS02440	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLA_RS02455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLA_RS02460	COG0484	heat shock protein binding
CLA_RS02465	COG0745	RESPONSE REGULATOR receiver
CLA_RS02470	COG0642	Histidine kinase
CLA_RS02475	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CLA_RS02500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CLA_RS02500	COG0519	Catalyzes the synthesis of GMP from XMP
CLA_RS02505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CLA_RS02525	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CLA_RS02535	COG1185	polyribonucleotide nucleotidyltransferase activity
CLA_RS02605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CLA_RS02615	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CLA_RS02620	COG0653	protein targeting
CLA_RS02625	COG2204	response regulator
CLA_RS02630	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLA_RS02640	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CLA_RS02645	COG0731	radical SAM domain protein
CLA_RS02660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CLA_RS02670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLA_RS02675	COG1160	GTP binding
CLA_RS02685	COG2233	PERMEase
CLA_RS02695	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CLA_RS02700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLA_RS02705	COG0284	orotidine-5'-phosphate decarboxylase activity
CLA_RS02715	COG0840	transmembrane signaling receptor activity
CLA_RS02720	COG0138	bifunctional purine biosynthesis protein purh
CLA_RS02725	COG0484	heat shock protein binding
CLA_RS02730	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLA_RS02745	COG0706	membrane insertase activity
CLA_RS02760	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CLA_RS02780	COG0824	Thioesterase
CLA_RS02805	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLA_RS02825	COG0500	methyltransferase
CLA_RS02840	COG2890	protein-(glutamine-N5) methyltransferase activity
CLA_RS02845	COG0501	Belongs to the peptidase M48B family
CLA_RS02850	COG0488	(ABC) transporter
CLA_RS02855	COG1408	metallophosphoesterase
CLA_RS02860	COG0688	phosphatidylethanolamine metabolic process
CLA_RS02865	COG2257	FlhB HrpN YscU SpaS Family
CLA_RS02890	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CLA_RS02905	COG0681	Belongs to the peptidase S26 family
CLA_RS02915	COG0343	queuine tRNA-ribosyltransferase activity
CLA_RS02930	COG0439	Biotin carboxylase
CLA_RS02950	COG0772	Belongs to the SEDS family
CLA_RS02970	COG0642	Histidine kinase
CLA_RS02985	COG1126	abc transporter atp-binding protein
CLA_RS02990	COG0765	amino acid transport
CLA_RS02995	COG1115	amino acid carrier protein
CLA_RS03000	COG0751	glycine-tRNA ligase activity
CLA_RS03005	COG0739	heme binding
CLA_RS03015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLA_RS03015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLA_RS03035	COG0772	Belongs to the SEDS family
CLA_RS03040	COG0564	pseudouridine synthase activity
CLA_RS03050	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CLA_RS03055	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLA_RS03070	COG0528	UMP kinase activity
CLA_RS03075	COG1758	RNA polymerase activity
CLA_RS03080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLA_RS03085	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLA_RS03110	COG0750	zinc metalloprotease
CLA_RS03120	COG1028	Short-chain dehydrogenase reductase Sdr
CLA_RS03125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLA_RS03130	COG0612	Peptidase, M16
CLA_RS03135	COG0167	dihydroorotate dehydrogenase activity
CLA_RS03140	COG1132	(ABC) transporter
CLA_RS03145	COG0215	cysteine-tRNA ligase activity
CLA_RS03150	COG0728	peptidoglycan biosynthetic process
CLA_RS03160	COG0632	four-way junction helicase activity
CLA_RS03165	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLA_RS03180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CLA_RS03185	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CLA_RS03190	COG0280	phosphate acetyltransferase
CLA_RS03195	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CLA_RS03200	COG1464	Belongs to the NlpA lipoprotein family
CLA_RS03210	COG2011	ABC-type metal ion transport system permease component
CLA_RS03215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLA_RS03230	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CLA_RS03235	COG0563	adenylate kinase activity
CLA_RS03245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLA_RS03250	COG0497	DNA recombination
CLA_RS03260	COG0084	hydrolase, TatD family'
CLA_RS03265	COG1388	LysM domain
CLA_RS03265	COG0741	lytic transglycosylase activity
CLA_RS03270	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CLA_RS03290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CLA_RS03305	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CLA_RS03310	COG0805	protein transport
CLA_RS03320	COG0701	Predicted permease
CLA_RS03325	COG0640	Transcriptional regulator
CLA_RS03330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLA_RS03335	COG0494	nUDIX hydrolase
CLA_RS03340	COG0527	aspartate kinase activity
CLA_RS03355	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CLA_RS03360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLA_RS03365	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CLA_RS03370	COG0196	riboflavin kinase activity
CLA_RS03375	COG2890	protein-(glutamine-N5) methyltransferase activity
CLA_RS03380	COG0012	GTP binding
CLA_RS03385	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CLA_RS03405	COG0698	ribose 5-phosphate isomerase
CLA_RS03410	COG2201	protein-glutamate methylesterase activity
CLA_RS03415	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLA_RS03425	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CLA_RS03430	COG0612	Peptidase, M16
CLA_RS03435	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLA_RS03440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLA_RS03445	COG0765	amino acid transport
CLA_RS03450	COG0765	amino acid transport
CLA_RS03475	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CLA_RS03485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLA_RS03490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLA_RS03495	COG0521	Mo-molybdopterin cofactor biosynthetic process
CLA_RS03515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLA_RS03520	COG0204	Acyl-transferase
CLA_RS03530	COG0047	phosphoribosylformylglycinamidine synthase activity
CLA_RS03535	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLA_RS03540	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CLA_RS03545	COG0793	Belongs to the peptidase S41A family
CLA_RS03550	COG0542	response to heat
CLA_RS03555	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CLA_RS03560	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CLA_RS03565	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CLA_RS03570	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CLA_RS03610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLA_RS03610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLA_RS03630	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CLA_RS03665	COG1794	racemase activity, acting on amino acids and derivatives
CLA_RS03670	COG0582	viral genome integration into host DNA
CLA_RS03675	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLA_RS03680	COG0303	'Molybdopterin
CLA_RS03705	COG0163	prenyltransferase activity
CLA_RS03710	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CLA_RS03715	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLA_RS03720	COG0124	histidyl-tRNA synthetase
CLA_RS03725	COG1166	arginine decarboxylase activity
CLA_RS03730	COG1045	serine acetyltransferase
CLA_RS03740	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLA_RS03745	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CLA_RS03755	COG0802	atpase or kinase
CLA_RS03760	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CLA_RS03765	COG0137	argininosuccinate synthase activity
CLA_RS03770	COG0359	binds to the 23S rRNA
CLA_RS03775	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CLA_RS03785	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CLA_RS03825	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CLA_RS03830	COG0181	hydroxymethylbilane synthase activity
CLA_RS03840	COG0442	prolyl-tRNA aminoacylation
CLA_RS03845	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CLA_RS03850	COG0142	geranyltranstransferase activity
CLA_RS03865	COG0546	phosphoglycolate phosphatase activity
CLA_RS03880	COG0789	Transcriptional regulator
CLA_RS03885	COG0484	heat shock protein binding
CLA_RS03890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLA_RS03895	COG0745	RESPONSE REGULATOR receiver
CLA_RS03900	COG0642	Histidine kinase
CLA_RS03905	COG0210	DNA helicase
CLA_RS03910	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CLA_RS03915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLA_RS03925	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLA_RS03930	COG0375	protein maturation
CLA_RS03935	COG0309	Hydrogenase expression formation protein (HypE)
CLA_RS03940	COG0409	Hydrogenase expression formation protein
CLA_RS03945	COG0298	carbon dioxide binding
CLA_RS03955	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CLA_RS03960	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CLA_RS03970	COG0534	Mate efflux family protein
CLA_RS03990	COG0581	inorganic phosphate transmembrane transporter activity
CLA_RS03995	COG0573	inorganic phosphate transmembrane transporter activity
CLA_RS04000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CLA_RS04010	COG2205	protein histidine kinase activity
CLA_RS04015	COG1528	Iron-storage protein
CLA_RS04025	COG0484	heat shock protein binding
CLA_RS04040	COG1333	cytochrome c biogenesis protein
CLA_RS04040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLA_RS04050	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLA_RS04055	COG0440	acetolactate synthase activity
CLA_RS04060	COG0028	Belongs to the TPP enzyme family
CLA_RS04070	COG1013	pyruvate-flavodoxin oxidoreductase activity
CLA_RS04075	COG0674	pyruvate-flavodoxin oxidoreductase activity
CLA_RS04075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CLA_RS04085	COG0039	L-malate dehydrogenase activity
CLA_RS04100	COG1196	nuclear chromosome segregation
CLA_RS04100	COG1674	ftsk spoiiie
CLA_RS04105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CLA_RS04305	COG3646	Phage regulatory protein
CLA_RS04360	COG2957	Belongs to the agmatine deiminase family
CLA_RS04440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CLA_RS04450	COG0587	DNA-directed DNA polymerase activity
CLA_RS04455	COG0693	protein deglycase activity
CLA_RS04465	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLA_RS04470	COG2957	Belongs to the agmatine deiminase family
CLA_RS04485	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CLA_RS04495	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CLA_RS04505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLA_RS04510	COG0765	amino acid transport
CLA_RS04520	COG2258	MOSC domain
CLA_RS04525	COG1252	NADH dehydrogenase
CLA_RS04530	COG0733	neurotransmitter:sodium symporter activity
CLA_RS04550	COG0191	fructose-bisphosphate aldolase activity
CLA_RS04555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLA_RS04560	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CLA_RS04565	COG0786	glutamate:sodium symporter activity
CLA_RS04575	COG1136	(ABC) transporter
CLA_RS04575	COG0577	efflux transmembrane transporter activity
CLA_RS04580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLA_RS04585	COG0778	Nitroreductase
CLA_RS04595	COG0492	ferredoxin-NADP+ reductase activity
CLA_RS04600	COG2813	Specifically methylates the guanine in position
CLA_RS04615	COG0134	indole-3-glycerol-phosphate synthase activity
CLA_RS04625	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CLA_RS04640	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CLA_RS04660	COG0443	Heat shock 70 kDa protein
CLA_RS04665	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CLA_RS04670	COG1420	regulation of RNA biosynthetic process
CLA_RS04685	COG2404	hydrolase activity, acting on ester bonds
CLA_RS04690	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLA_RS04695	COG1959	2 iron, 2 sulfur cluster binding
CLA_RS04700	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CLA_RS04705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLA_RS04705	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLA_RS04710	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLA_RS04725	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CLA_RS04730	COG0557	exoribonuclease II activity
CLA_RS04740	COG0360	Binds together with S18 to 16S ribosomal RNA
CLA_RS04745	COG0629	single-stranded DNA binding
CLA_RS04750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CLA_RS04755	COG2095	MarC family integral membrane protein
CLA_RS04775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLA_RS04780	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CLA_RS04790	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLA_RS04810	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CLA_RS04820	COG2814	Major facilitator Superfamily
CLA_RS04830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLA_RS04835	COG1757	Na H antiporter
CLA_RS04840	COG4221	oxidoreductase activity
CLA_RS04845	COG0666	response to abiotic stimulus
CLA_RS04870	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CLA_RS04890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLA_RS04895	COG1338	Plays a role in the flagellum-specific transport system
CLA_RS04905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLA_RS04930	COG1393	Belongs to the ArsC family
CLA_RS04935	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CLA_RS04945	COG0335	large ribosomal subunit rRNA binding
CLA_RS04950	COG0336	Belongs to the RNA methyltransferase TrmD family
CLA_RS04960	COG1837	Belongs to the UPF0109 family
CLA_RS04965	COG0228	four-way junction DNA binding
CLA_RS04970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLA_RS04975	COG0564	pseudouridine synthase activity
CLA_RS04980	COG1519	Transferase
CLA_RS04990	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CLA_RS04995	COG0752	glycyl-tRNA synthetase alpha subunit
CLA_RS05005	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CLA_RS05010	COG0826	peptidase U32
CLA_RS05020	COG0174	glutamine synthetase
CLA_RS05025	COG0788	formyltetrahydrofolate deformylase activity
CLA_RS05030	COG0617	tRNA 3'-terminal CCA addition
CLA_RS05045	COG2807	transmembrane transport
CLA_RS05060	COG3043	anaerobic respiration
CLA_RS05065	COG0348	domain, Protein
CLA_RS05070	COG0437	4 iron, 4 sulfur cluster binding
CLA_RS05075	COG0243	molybdopterin cofactor binding
CLA_RS05085	COG4786	Flagellar basal body rod
CLA_RS05090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLA_RS05095	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CLA_RS05105	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CLA_RS05120	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CLA_RS05125	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CLA_RS05140	COG0840	transmembrane signaling receptor activity
CLA_RS05150	COG0459	protein refolding
CLA_RS05155	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CLA_RS05175	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLA_RS05185	COG0739	heme binding
CLA_RS05190	COG0285	dihydrofolate synthase activity
CLA_RS05205	COG0495	leucyl-tRNA aminoacylation
CLA_RS05215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLA_RS05220	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLA_RS05225	COG1862	Preprotein translocase
CLA_RS05230	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CLA_RS05235	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CLA_RS05240	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CLA_RS05245	COG0540	Belongs to the ATCase OTCase family
CLA_RS05260	COG0210	DNA helicase
CLA_RS05280	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CLA_RS05295	COG0542	response to heat
CLA_RS05300	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CLA_RS05305	COG1815	bacterial-type flagellum-dependent cell motility
CLA_RS05310	COG1558	bacterial-type flagellum-dependent cell motility
CLA_RS05315	COG1677	Flagellar hook-basal body complex protein FliE
CLA_RS05320	COG0768	penicillin binding
CLA_RS05325	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CLA_RS05330	COG0673	inositol 2-dehydrogenase activity
CLA_RS05345	COG0424	maF-like protein
CLA_RS05355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CLA_RS05365	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CLA_RS05370	COG2217	Heavy metal translocating P-type atpase
CLA_RS05390	COG0217	transcriptional regulatory protein
CLA_RS05395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLA_RS05405	COG0586	Pfam SNARE associated Golgi protein
CLA_RS05415	COG3610	response to peptide
CLA_RS05420	COG0018	arginyl-trna synthetase
CLA_RS05425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLA_RS05430	COG0194	GDP metabolic process
CLA_RS05440	COG1684	flagellar biosynthetic protein fliR
CLA_RS05445	COG1136	(ABC) transporter
CLA_RS05450	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CLA_RS05455	COG0052	Belongs to the universal ribosomal protein uS2 family
CLA_RS05470	COG0723	plastoquinol--plastocyanin reductase activity
CLA_RS05485	COG1496	oxidoreductase activity
CLA_RS05495	COG0642	Histidine kinase
CLA_RS05520	COG4773	Receptor
CLA_RS05535	COG0683	leucine binding
CLA_RS05560	COG1333	cytochrome c biogenesis protein
CLA_RS05560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLA_RS05570	COG0481	GTPase activity
CLA_RS05590	COG0352	thiamine-phosphate diphosphorylase activity
CLA_RS05595	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CLA_RS05600	COG0351	phosphomethylpyrimidine kinase
CLA_RS05605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLA_RS05620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLA_RS05625	COG0113	porphobilinogen synthase activity
CLA_RS05635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLA_RS05640	COG2181	nitrate reductase activity
CLA_RS05640	COG0247	lactate metabolic process
CLA_RS05650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLA_RS05670	COG1999	signal sequence binding
CLA_RS05675	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLA_RS05690	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLA_RS05705	COG0471	metal ion transport
CLA_RS05710	COG0352	thiamine-phosphate diphosphorylase activity
CLA_RS05715	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CLA_RS05740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLA_RS05745	COG1280	lysine exporter protein (LysE YggA)
CLA_RS05750	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CLA_RS05755	COG1193	negative regulation of DNA recombination
CLA_RS05780	COG0517	IMP dehydrogenase activity
CLA_RS05780	COG0516	GMP reductase activity
CLA_RS05785	COG0154	amidase activity
CLA_RS05790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CLA_RS05795	COG1058	Belongs to the CinA family
CLA_RS05795	COG1546	Belongs to the CinA family
CLA_RS05810	COG1136	(ABC) transporter
CLA_RS05810	COG0577	efflux transmembrane transporter activity
CLA_RS05835	COG0672	)-iron permease
CLA_RS05860	COG0275	rRNA processing
CLA_RS05875	COG0849	cell division
CLA_RS05880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLA_RS05890	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CLA_RS05895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLA_RS05920	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLA_RS05925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLA_RS05940	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CLA_RS05945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CLA_RS05955	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CLA_RS05960	COG0537	adenosine 5'-monophosphoramidase activity
CLA_RS05965	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CLA_RS05975	COG0733	neurotransmitter:sodium symporter activity
CLA_RS05980	COG0733	neurotransmitter:sodium symporter activity
CLA_RS05985	COG0733	neurotransmitter:sodium symporter activity
CLA_RS05990	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLA_RS06010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CLA_RS06015	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CLA_RS06020	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLA_RS06035	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CLA_RS06040	COG0552	protein localization to endoplasmic reticulum
CLA_RS06045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLA_RS06070	COG1295	ribonuclease BN
CLA_RS06085	COG0739	heme binding
CLA_RS06090	COG2239	Acts as a magnesium transporter
CLA_RS06095	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CLA_RS06100	COG0305	Participates in initiation and elongation during chromosome replication
CLA_RS06105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLA_RS06110	COG0776	regulation of translation
CLA_RS06120	COG0463	Glycosyl transferase, family 2
CLA_RS06125	COG1028	Short-chain dehydrogenase reductase Sdr
CLA_RS06130	COG1083	cytidylyl-transferase
CLA_RS06140	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CLA_RS06150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLA_RS06150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLA_RS06155	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CLA_RS06160	COG2089	acid synthase
CLA_RS06165	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLA_RS06170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLA_RS06185	COG0463	Glycosyl transferase, family 2
CLA_RS06190	COG1442	glycosyl transferase family 8
CLA_RS06190	COG1216	Glycosyl transferase, family 2
CLA_RS06195	COG1216	Glycosyl transferase, family 2
CLA_RS06195	COG1442	glycosyl transferase family 8
CLA_RS06200	COG1442	glycosyl transferase family 8
CLA_RS06200	COG1216	Glycosyl transferase, family 2
CLA_RS06210	COG1442	glycosyl transferase family 8
CLA_RS06210	COG1216	Glycosyl transferase, family 2
CLA_RS06225	COG0859	PFAM glycosyl transferase family 9
CLA_RS06235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLA_RS06240	COG1132	(ABC) transporter
CLA_RS06245	COG0438	transferase activity, transferring glycosyl groups
CLA_RS06250	COG0438	transferase activity, transferring glycosyl groups
CLA_RS06255	COG1287	oligosaccharyl transferase activity
CLA_RS06260	COG0438	transferase activity, transferring glycosyl groups
CLA_RS06265	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CLA_RS06270	COG0110	maltose O-acetyltransferase activity
CLA_RS06275	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLA_RS06280	COG1086	Polysaccharide biosynthesis protein
CLA_RS06285	COG0745	RESPONSE REGULATOR receiver
CLA_RS06290	COG2264	protein methyltransferase activity
CLA_RS06295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLA_RS06305	COG1183	phosphatidylcholine synthase activity
CLA_RS06320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLA_RS06335	COG1607	acyl-coa hydrolase
CLA_RS06340	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLA_RS06355	COG2255	four-way junction helicase activity
CLA_RS06360	COG0628	permease
CLA_RS06365	COG2814	Major facilitator Superfamily
CLA_RS06370	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CLA_RS06410	COG1921	L-seryl-tRNASec selenium transferase activity
CLA_RS06415	COG3276	selenocysteine insertion sequence binding
CLA_RS06430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CLA_RS06435	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CLA_RS06440	COG0280	phosphate acetyltransferase
CLA_RS06440	COG0281	malic enzyme
CLA_RS06445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLA_RS06455	COG0439	Biotin carboxylase
CLA_RS06460	COG0511	ligase activity, forming carbon-carbon bonds
CLA_RS06465	COG0717	Belongs to the dCTP deaminase family
CLA_RS06470	COG1086	Polysaccharide biosynthesis protein
CLA_RS06475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLA_RS06480	COG4310	Domain of unknown function (DUF2172)
CLA_RS06505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLA_RS06535	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLA_RS06545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLA_RS06575	COG1083	cytidylyl-transferase
CLA_RS06580	COG3980	spore coat polysaccharide biosynthesis protein
CLA_RS06585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLA_RS06600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLA_RS06605	COG0107	imidazoleglycerol-phosphate synthase activity
CLA_RS06610	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLA_RS06620	COG0730	response to heat
CLA_RS06625	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLA_RS06630	COG0840	transmembrane signaling receptor activity
CLA_RS06635	COG0450	alkyl hydroperoxide reductase
CLA_RS06645	COG0105	UTP biosynthetic process
CLA_RS06655	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CLA_RS06660	COG0416	fatty acid biosynthetic process
CLA_RS06670	COG1360	Flagellar Motor Protein
CLA_RS06675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CLA_RS06685	COG0477	Major facilitator Superfamily
CLA_RS06695	COG1238	metal cluster binding
CLA_RS06700	COG0133	tryptophan synthase activity
CLA_RS06705	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CLA_RS06710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CLA_RS06715	COG1966	Carbon starvation protein
CLA_RS06725	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CLA_RS06730	COG1570	exodeoxyribonuclease VII activity
CLA_RS06735	COG2226	methyltransferase
CLA_RS06750	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CLA_RS06760	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLA_RS06770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLA_RS06785	COG0019	diaminopimelate decarboxylase activity
CLA_RS06795	COG0193	aminoacyl-tRNA hydrolase activity
CLA_RS06800	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CLA_RS06805	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CLA_RS06815	COG0835	chemotaxis
CLA_RS06820	COG0643	Histidine kinase
CLA_RS06820	COG2198	Histidine kinase
CLA_RS06820	COG0784	Response regulator, receiver
CLA_RS06825	COG0784	Response regulator, receiver
CLA_RS06825	COG0835	chemotaxis
CLA_RS06835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLA_RS06840	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLA_RS06850	COG3021	interspecies interaction between organisms
CLA_RS06860	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLA_RS06865	COG3069	C4-dicarboxylate transmembrane transporter activity
CLA_RS06870	COG3340	Belongs to the peptidase S51 family
CLA_RS06875	COG0725	ABC transporter, periplasmic molybdate-binding protein
CLA_RS06880	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CLA_RS06900	COG4106	trans-aconitate 2-methyltransferase activity
CLA_RS06905	COG2830	Protein of unknown function (DUF452)
CLA_RS06920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLA_RS06925	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CLA_RS06930	COG2076	Multidrug Resistance protein
CLA_RS06935	COG2076	Multidrug Resistance protein
CLA_RS06950	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CLA_RS06960	COG1077	Cell shape determining protein MreB Mrl
CLA_RS06965	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CLA_RS06970	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLA_RS06975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLA_RS06980	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CLA_RS06985	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CLA_RS06990	COG1942	4-Oxalocrotonate Tautomerase
CLA_RS07000	COG0330	HflC and HflK could
CLA_RS07015	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CLA_RS07020	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CLA_RS07030	COG0492	ferredoxin-NADP+ reductase activity
CLA_RS07035	COG3118	belongs to the thioredoxin family
CLA_RS07040	COG0792	nuclease activity
CLA_RS07045	COG0460	homoserine dehydrogenase
CLA_RS07050	COG0436	Aminotransferase
CLA_RS07070	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CLA_RS07075	COG0254	rRNA binding
CLA_RS07080	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CLA_RS07100	COG0602	queuosine metabolic process
CLA_RS07105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLA_RS07125	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLA_RS07135	COG1007	ATP synthesis coupled electron transport
CLA_RS07140	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLA_RS07145	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CLA_RS07155	COG0839	Belongs to the complex I subunit 6 family
CLA_RS07165	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CLA_RS07190	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLA_RS07195	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLA_RS07200	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLA_RS07205	COG4608	Belongs to the ABC transporter superfamily
CLA_RS07215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLA_RS07230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLA_RS07240	COG1139	Iron-sulfur cluster binding protein
CLA_RS07245	COG0247	lactate metabolic process
CLA_RS07270	COG0243	molybdopterin cofactor binding
CLA_RS07275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CLA_RS07330	COG0861	Integral membrane protein TerC family
CLA_RS07335	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLA_RS07340	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CLA_RS07340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CLA_RS07355	COG0606	chelatase, subunit chli
CLA_RS07360	COG0242	peptide deformylase activity
CLA_RS07370	COG0740	serine-type endopeptidase activity
CLA_RS07375	COG0544	peptidyl-prolyl cis-trans isomerase activity
CLA_RS07380	COG0302	gtp cyclohydrolase
CLA_RS07385	COG1157	protein secretion by the type III secretion system
CLA_RS07415	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CLA_RS07420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CLA_RS07430	COG2860	membrane
CLA_RS07440	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CLA_RS07450	COG0328	RNA-DNA hybrid ribonuclease activity
CLA_RS07460	COG0358	DNA primase activity
CLA_RS07470	COG0840	transmembrane signaling receptor activity
CLA_RS07475	COG4953	penicillin-binding protein 1C
CLA_RS07495	COG0668	transmembrane transport
CLA_RS07500	COG0288	reversible hydration of carbon dioxide
CLA_RS07505	COG0670	Belongs to the BI1 family
CLA_RS07510	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLA_RS07515	COG0233	cytoplasmic translational termination
CLA_RS07520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CLA_RS07530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLA_RS07545	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CLA_RS07560	COG1217	gtp-binding protein TYPA
CLA_RS07580	COG1749	Flagellar hook protein flgE
CLA_RS07595	COG2184	nucleotidyltransferase activity
CLA_RS07610	COG1840	ABC-type Fe3 transport system, periplasmic component
CLA_RS07620	COG4615	Cyclic peptide transporter
CLA_RS07660	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CLA_RS07665	COG0575	Belongs to the CDS family
CLA_RS07685	COG2056	Na+-H+ antiporter family
CLA_RS07690	COG0129	dihydroxy-acid dehydratase activity
CLA_RS07715	COG0840	transmembrane signaling receptor activity
CLA_RS07720	COG0840	transmembrane signaling receptor activity
CLA_RS07730	COG1222	aaa ATPase
CLA_RS07740	COG1666	GTP binding
CLA_RS07745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLA_RS07750	COG0754	glutathionylspermidine amidase activity
CLA_RS07760	COG1280	lysine exporter protein (LysE YggA)
CLA_RS07765	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CLA_RS07800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLA_RS07805	COG2226	methyltransferase
CLA_RS07810	COG1981	membrane
CLA_RS07820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLA_RS07830	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CLA_RS07830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CLA_RS07850	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CLA_RS07860	COG0708	Exodeoxyribonuclease III
CLA_RS08005	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLA_RS08035	COG1793	dna ligase
CLA_RS08085	COG0741	lytic transglycosylase activity
CLA_RS08095	COG0642	Histidine kinase
CLA_RS08135	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CLA_RS08150	COG1401	restriction endodeoxyribonuclease activity
CLA_RS08175	COG1843	Required for flagellar hook formation. May act as a scaffolding protein