locus-tag	class	description
CMCT_RS00010	COG0592	DNA-directed DNA polymerase activity
CMCT_RS00015	COG0187	DNA topoisomerase II activity
CMCT_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CMCT_RS00070	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CMCT_RS00070	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMCT_RS00090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMCT_RS00095	COG3177	Filamentation induced by cAMP protein fic
CMCT_RS00100	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CMCT_RS00105	COG0564	pseudouridine synthase activity
CMCT_RS00110	COG1592	Rubrerythrin
CMCT_RS00155	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CMCT_RS00165	COG0517	IMP dehydrogenase activity
CMCT_RS00165	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CMCT_RS00170	COG1187	pseudouridine synthase activity
CMCT_RS00175	COG1691	(AIR) carboxylase
CMCT_RS00180	COG1606	tRNA processing
CMCT_RS00185	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CMCT_RS00190	COG3875	lactate racemase activity
CMCT_RS00195	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CMCT_RS00200	COG1115	amino acid carrier protein
CMCT_RS00205	COG0579	oxidoreductase
CMCT_RS00215	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CMCT_RS00215	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CMCT_RS00250	COG1027	Aspartate ammonia-lyase
CMCT_RS00255	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CMCT_RS00260	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CMCT_RS00265	COG0237	dephospho-CoA kinase activity
CMCT_RS00270	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CMCT_RS00280	COG0840	transmembrane signaling receptor activity
CMCT_RS00350	COG0484	heat shock protein binding
CMCT_RS00355	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMCT_RS00360	COG3287	FIST C domain
CMCT_RS00360	COG2199	diguanylate cyclase activity
CMCT_RS00360	COG2200	EAL domain
CMCT_RS00370	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMCT_RS00380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CMCT_RS00400	COG0243	molybdopterin cofactor binding
CMCT_RS00405	COG0437	4 iron, 4 sulfur cluster binding
CMCT_RS00415	COG3301	Polysulphide reductase, NrfD
CMCT_RS00450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CMCT_RS00460	COG0861	Integral membrane protein TerC family
CMCT_RS00500	COG0602	queuosine metabolic process
CMCT_RS00530	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CMCT_RS00550	COG0436	Aminotransferase
CMCT_RS00555	COG0460	homoserine dehydrogenase
CMCT_RS00560	COG0792	nuclease activity
CMCT_RS00565	COG3118	belongs to the thioredoxin family
CMCT_RS00575	COG0492	ferredoxin-NADP+ reductase activity
CMCT_RS00580	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CMCT_RS00595	COG0109	protoheme IX farnesyltransferase activity
CMCT_RS00605	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CMCT_RS00615	COG1942	4-Oxalocrotonate Tautomerase
CMCT_RS00620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CMCT_RS00625	COG2194	sulfuric ester hydrolase activity
CMCT_RS00640	COG0140	phosphoribosyl-ATP diphosphatase activity
CMCT_RS00640	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CMCT_RS00665	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CMCT_RS00675	COG4615	Cyclic peptide transporter
CMCT_RS00705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CMCT_RS00720	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CMCT_RS00735	COG0754	glutathionylspermidine amidase activity
CMCT_RS00740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMCT_RS00750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CMCT_RS00765	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CMCT_RS00770	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CMCT_RS00775	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CMCT_RS00785	COG3104	oligopeptide transport
CMCT_RS00795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CMCT_RS00810	COG0784	Response regulator, receiver
CMCT_RS00810	COG0835	chemotaxis
CMCT_RS00815	COG2198	Histidine kinase
CMCT_RS00815	COG0784	Response regulator, receiver
CMCT_RS00815	COG0643	Histidine kinase
CMCT_RS00820	COG0835	chemotaxis
CMCT_RS00830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CMCT_RS00835	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CMCT_RS00840	COG0193	aminoacyl-tRNA hydrolase activity
CMCT_RS00850	COG0019	diaminopimelate decarboxylase activity
CMCT_RS00855	COG0077	Prephenate dehydratase
CMCT_RS00855	COG1605	Chorismate mutase
CMCT_RS00860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CMCT_RS00870	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CMCT_RS00880	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CMCT_RS00895	COG2226	methyltransferase
CMCT_RS00900	COG1570	exodeoxyribonuclease VII activity
CMCT_RS00940	COG0569	domain protein
CMCT_RS00940	COG0475	glutathione-regulated potassium exporter activity
CMCT_RS00945	COG4797	methyltransferase
CMCT_RS00945	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CMCT_RS00950	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CMCT_RS00955	COG1028	Short-chain dehydrogenase reductase Sdr
CMCT_RS00960	COG1083	cytidylyl-transferase
CMCT_RS00975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CMCT_RS00985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CMCT_RS00985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CMCT_RS00990	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CMCT_RS00995	COG2089	acid synthase
CMCT_RS01005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CMCT_RS01010	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CMCT_RS01020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CMCT_RS01040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CMCT_RS01065	COG1086	Polysaccharide biosynthesis protein
CMCT_RS01070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CMCT_RS01075	COG1083	cytidylyl-transferase
CMCT_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CMCT_RS01085	COG2610	gluconate transmembrane transporter activity
CMCT_RS01090	COG1929	Belongs to the glycerate kinase type-1 family
CMCT_RS01095	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CMCT_RS01115	COG0575	Belongs to the CDS family
CMCT_RS01130	COG4774	siderophore transport
CMCT_RS01140	COG0746	molybdenum cofactor guanylyltransferase activity
CMCT_RS01155	COG0439	Biotin carboxylase
CMCT_RS01175	COG0717	Belongs to the dCTP deaminase family
CMCT_RS01215	COG0398	Pfam SNARE associated Golgi protein
CMCT_RS01270	COG0745	RESPONSE REGULATOR receiver
CMCT_RS01285	COG0438	transferase activity, transferring glycosyl groups
CMCT_RS01300	COG3842	ATPase activity
CMCT_RS01345	COG1987	bacterial-type flagellum assembly
CMCT_RS01360	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CMCT_RS01415	COG0745	RESPONSE REGULATOR receiver
CMCT_RS01435	COG1053	succinate dehydrogenase
CMCT_RS01435	COG3976	FMN-binding domain protein
CMCT_RS01445	COG2986	histidine ammonia-lyase
CMCT_RS01465	COG0438	transferase activity, transferring glycosyl groups
CMCT_RS01470	COG0726	polysaccharide deacetylase
CMCT_RS01475	COG1216	Glycosyl transferase, family 2
CMCT_RS01475	COG1442	glycosyl transferase family 8
CMCT_RS01490	COG0297	glycogen (starch) synthase activity
CMCT_RS01490	COG0438	transferase activity, transferring glycosyl groups
CMCT_RS01510	COG0859	PFAM glycosyl transferase family 9
CMCT_RS01520	COG1755	Isoprenylcysteine carboxyl methyltransferase
CMCT_RS01540	COG1793	dna ligase
CMCT_RS01555	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CMCT_RS01560	COG2244	polysaccharide biosynthetic process
CMCT_RS01570	COG1215	transferase activity, transferring glycosyl groups
CMCT_RS01575	COG0438	transferase activity, transferring glycosyl groups
CMCT_RS01585	COG0438	transferase activity, transferring glycosyl groups
CMCT_RS01600	COG0438	transferase activity, transferring glycosyl groups
CMCT_RS01605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CMCT_RS01610	COG0110	maltose O-acetyltransferase activity
CMCT_RS01615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CMCT_RS01620	COG1086	Polysaccharide biosynthesis protein
CMCT_RS01630	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CMCT_RS01635	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CMCT_RS01645	COG0745	RESPONSE REGULATOR receiver
CMCT_RS01650	COG2264	protein methyltransferase activity
CMCT_RS01655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CMCT_RS01665	COG1183	phosphatidylcholine synthase activity
CMCT_RS01670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CMCT_RS01675	COG3830	Belongs to the UPF0237 family
CMCT_RS01680	COG2848	UPF0210 protein
CMCT_RS01690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CMCT_RS01695	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CMCT_RS01725	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CMCT_RS01750	COG0505	Belongs to the CarA family
CMCT_RS01765	COG0745	RESPONSE REGULATOR receiver
CMCT_RS01770	COG3278	Belongs to the heme-copper respiratory oxidase family
CMCT_RS01810	COG1074	ATP-dependent DNA helicase activity
CMCT_RS01810	COG1074	ATP-dependent DNA helicase activity
CMCT_RS01815	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CMCT_RS01820	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CMCT_RS01830	COG0546	phosphoglycolate phosphatase activity
CMCT_RS01835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CMCT_RS01835	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CMCT_RS01835	COG1013	pyruvate-flavodoxin oxidoreductase activity
CMCT_RS01835	COG0674	pyruvate-flavodoxin oxidoreductase activity
CMCT_RS01840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CMCT_RS01845	COG0765	amino acid transport
CMCT_RS01850	COG1126	abc transporter atp-binding protein
CMCT_RS01860	COG0351	phosphomethylpyrimidine kinase
CMCT_RS01865	COG0352	thiamine-phosphate diphosphorylase activity
CMCT_RS01870	COG0840	transmembrane signaling receptor activity
CMCT_RS01875	COG0166	Belongs to the GPI family
CMCT_RS01885	COG3839	Belongs to the ABC transporter superfamily
CMCT_RS01890	COG4662	Binding-protein-dependent transport system inner membrane component
CMCT_RS01895	COG2998	abc-type tungstate transport system, permease component
CMCT_RS01900	COG1739	Uncharacterized protein family UPF0029
CMCT_RS01905	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CMCT_RS01915	COG0745	RESPONSE REGULATOR receiver
CMCT_RS01920	COG0642	Histidine kinase
CMCT_RS01925	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CMCT_RS01935	COG1053	succinate dehydrogenase
CMCT_RS01940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CMCT_RS01950	COG2353	YceI-like domain
CMCT_RS01955	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CMCT_RS01965	COG0716	FMN binding
CMCT_RS01980	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CMCT_RS01985	COG0848	biopolymer transport protein
CMCT_RS01990	COG0811	peptide transport
CMCT_RS01995	COG1959	2 iron, 2 sulfur cluster binding
CMCT_RS02000	COG2910	NAD(P)H-binding
CMCT_RS02020	COG0481	GTPase activity
CMCT_RS02025	COG4310	Domain of unknown function (DUF2172)
CMCT_RS02030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CMCT_RS02055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CMCT_RS02060	COG1942	4-Oxalocrotonate Tautomerase
CMCT_RS02075	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CMCT_RS02095	COG2204	response regulator
CMCT_RS02100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CMCT_RS02110	COG0731	radical SAM domain protein
CMCT_RS02115	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CMCT_RS02150	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CMCT_RS02155	COG0519	Catalyzes the synthesis of GMP from XMP
CMCT_RS02160	COG0484	heat shock protein binding
CMCT_RS02165	COG0501	Belongs to the peptidase M48B family
CMCT_RS02180	COG0357	Ribosomal RNA small subunit methyltransferase G
CMCT_RS02185	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CMCT_RS02190	COG0113	porphobilinogen synthase activity
CMCT_RS02205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CMCT_RS02225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CMCT_RS02250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CMCT_RS02260	COG2197	response regulator
CMCT_RS02295	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CMCT_RS02300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CMCT_RS02315	COG0250	Participates in transcription elongation, termination and antitermination
CMCT_RS02320	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CMCT_RS02335	COG0222	ribosome binding
CMCT_RS02340	COG0085	RNA polymerase activity
CMCT_RS02345	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMCT_RS02355	COG1757	Na H antiporter
CMCT_RS02360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CMCT_RS02365	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CMCT_RS02375	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CMCT_RS02390	COG0778	Nitroreductase
CMCT_RS02400	COG1058	Belongs to the CinA family
CMCT_RS02400	COG1546	Belongs to the CinA family
CMCT_RS02415	COG0516	GMP reductase activity
CMCT_RS02415	COG0517	IMP dehydrogenase activity
CMCT_RS02420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CMCT_RS02425	COG1722	exodeoxyribonuclease VII activity
CMCT_RS02435	COG0519	Catalyzes the synthesis of GMP from XMP
CMCT_RS02450	COG1193	negative regulation of DNA recombination
CMCT_RS02455	COG3287	FIST C domain
CMCT_RS02455	COG2199	diguanylate cyclase activity
CMCT_RS02455	COG2200	EAL domain
CMCT_RS02465	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CMCT_RS02480	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CMCT_RS02500	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMCT_RS02540	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CMCT_RS02545	COG0243	molybdopterin cofactor binding
CMCT_RS02550	COG0437	4 iron, 4 sulfur cluster binding
CMCT_RS02555	COG3301	Polysulphide reductase, NrfD
CMCT_RS02565	COG5002	protein histidine kinase activity
CMCT_RS02585	COG0437	4 iron, 4 sulfur cluster binding
CMCT_RS02590	COG0348	domain, Protein
CMCT_RS02595	COG3043	anaerobic respiration
CMCT_RS02615	COG0783	Belongs to the Dps family
CMCT_RS02620	COG0642	Histidine kinase
CMCT_RS02650	COG4773	Receptor
CMCT_RS02705	COG2824	Alkylphosphonate utilization operon protein PhnA
CMCT_RS02715	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CMCT_RS02725	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CMCT_RS02735	COG0497	DNA recombination
CMCT_RS02745	COG0084	hydrolase, TatD family'
CMCT_RS02750	COG1388	LysM domain
CMCT_RS02750	COG1705	Flagellar rod assembly protein muramidase FlgJ
CMCT_RS02755	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CMCT_RS02765	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CMCT_RS02780	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CMCT_RS02795	COG0768	penicillin binding
CMCT_RS02800	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CMCT_RS02815	COG1151	hydroxylamine reductase activity
CMCT_RS02845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CMCT_RS02845	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CMCT_RS02855	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CMCT_RS02880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CMCT_RS02885	COG0840	transmembrane signaling receptor activity
CMCT_RS02910	COG1408	metallophosphoesterase
CMCT_RS02915	COG0688	phosphatidylethanolamine metabolic process
CMCT_RS02935	COG0488	(ABC) transporter
CMCT_RS02940	COG4310	Domain of unknown function (DUF2172)
CMCT_RS02975	COG0477	Major facilitator Superfamily
CMCT_RS02980	COG0745	RESPONSE REGULATOR receiver
CMCT_RS02985	COG0642	Histidine kinase
CMCT_RS02990	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CMCT_RS03000	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMCT_RS03005	COG0733	neurotransmitter:sodium symporter activity
CMCT_RS03010	COG0733	neurotransmitter:sodium symporter activity
CMCT_RS03015	COG0733	neurotransmitter:sodium symporter activity
CMCT_RS03045	COG1999	signal sequence binding
CMCT_RS03105	COG0745	RESPONSE REGULATOR receiver
CMCT_RS03115	COG0489	protein tyrosine kinase activity
CMCT_RS03145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CMCT_RS03155	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CMCT_RS03160	COG2252	PERMEase
CMCT_RS03205	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CMCT_RS03230	COG1301	dicarboxylic acid transport
CMCT_RS03245	COG0789	Transcriptional regulator
CMCT_RS03250	COG0484	heat shock protein binding
CMCT_RS03270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CMCT_RS03275	COG2258	MOSC domain
CMCT_RS03280	COG3263	regulation of cellular component size
CMCT_RS03290	COG0642	Histidine kinase
CMCT_RS03295	COG0745	RESPONSE REGULATOR receiver
CMCT_RS03325	COG0142	geranyltranstransferase activity
CMCT_RS03330	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CMCT_RS03350	COG0181	hydroxymethylbilane synthase activity
CMCT_RS03355	COG1580	Controls the rotational direction of flagella during chemotaxis
CMCT_RS03360	COG0736	holo-[acyl-carrier-protein] synthase activity
CMCT_RS03375	COG1420	regulation of RNA biosynthetic process
CMCT_RS03390	COG4232	protein-disulfide reductase activity
CMCT_RS03400	COG0586	Pfam SNARE associated Golgi protein
CMCT_RS03405	COG1280	lysine exporter protein (LysE YggA)
CMCT_RS03420	COG1464	Belongs to the NlpA lipoprotein family
CMCT_RS03455	COG2011	ABC-type metal ion transport system permease component
CMCT_RS03460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CMCT_RS03475	COG4953	penicillin-binding protein 1C
CMCT_RS03505	COG0776	regulation of translation
CMCT_RS03510	COG3022	response to hydroperoxide
CMCT_RS03515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CMCT_RS03520	COG1196	nuclear chromosome segregation
CMCT_RS03520	COG1674	ftsk spoiiie
CMCT_RS03535	COG0748	coenzyme F420 binding
CMCT_RS03545	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CMCT_RS03565	COG0191	fructose-bisphosphate aldolase activity
CMCT_RS03570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CMCT_RS03575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CMCT_RS03585	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CMCT_RS03590	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CMCT_RS03600	COG1663	tetraacyldisaccharide 4'-kinase activity
CMCT_RS03610	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CMCT_RS03615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CMCT_RS03625	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CMCT_RS03625	COG2050	protein possibly involved in aromatic compounds catabolism
CMCT_RS03640	COG1305	Transglutaminase-like
CMCT_RS03655	COG2195	Cleaves the N-terminal amino acid of tripeptides
CMCT_RS03660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CMCT_RS03665	COG1629	transport
CMCT_RS03665	COG4771	TonB-dependent receptor
CMCT_RS03670	COG4786	Flagellar basal body rod
CMCT_RS03675	COG4786	Flagellar basal body rod
CMCT_RS03690	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CMCT_RS03695	COG1687	branched-chain amino acid
CMCT_RS03700	COG0252	asparaginase activity
CMCT_RS03715	COG0066	3-isopropylmalate dehydratase activity
CMCT_RS03720	COG0473	3-isopropylmalate dehydrogenase activity
CMCT_RS03740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CMCT_RS03755	COG0751	glycine-tRNA ligase activity
CMCT_RS03805	COG0243	molybdopterin cofactor binding
CMCT_RS03810	COG3383	formate dehydrogenase (NAD+) activity
CMCT_RS03815	COG2860	membrane
CMCT_RS03820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CMCT_RS03835	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CMCT_RS03855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CMCT_RS03865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CMCT_RS03875	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CMCT_RS03880	COG1360	Flagellar Motor Protein
CMCT_RS03885	COG1338	Plays a role in the flagellum-specific transport system
CMCT_RS03915	COG0642	Histidine kinase
CMCT_RS03920	COG0745	RESPONSE REGULATOR receiver
CMCT_RS03935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CMCT_RS03955	COG2184	nucleotidyltransferase activity
CMCT_RS03970	COG1127	ABC transporter
CMCT_RS03975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CMCT_RS03980	COG0343	queuine tRNA-ribosyltransferase activity
CMCT_RS04085	COG3646	Phage regulatory protein
CMCT_RS04120	COG0582	viral genome integration into host DNA
CMCT_RS04145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CMCT_RS04150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CMCT_RS04155	COG0521	Mo-molybdopterin cofactor biosynthetic process
CMCT_RS04160	COG2151	metal-sulfur cluster biosynthetic enzyme
CMCT_RS04190	COG1166	arginine decarboxylase activity
CMCT_RS04195	COG0124	histidyl-tRNA synthetase
CMCT_RS04205	COG0298	carbon dioxide binding
CMCT_RS04210	COG0409	Hydrogenase expression formation protein
CMCT_RS04215	COG0309	Hydrogenase expression formation protein (HypE)
CMCT_RS04225	COG0628	permease
CMCT_RS04235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CMCT_RS04245	COG0039	L-malate dehydrogenase activity
CMCT_RS04255	COG0674	pyruvate-flavodoxin oxidoreductase activity
CMCT_RS04255	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CMCT_RS04260	COG1013	pyruvate-flavodoxin oxidoreductase activity
CMCT_RS04270	COG1053	succinate dehydrogenase
CMCT_RS04275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CMCT_RS04280	COG2048	Heterodisulfide reductase, subunit B
CMCT_RS04295	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CMCT_RS04320	COG3951	Flagellar rod assembly protein muramidase FlgJ
CMCT_RS04350	COG0730	response to heat
CMCT_RS04370	COG1472	Belongs to the glycosyl hydrolase 3 family
CMCT_RS04385	COG0163	prenyltransferase activity
CMCT_RS04400	COG0303	'Molybdopterin
CMCT_RS04405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMCT_RS04415	COG2833	Protein of unknown function (DUF455)
CMCT_RS04425	COG0814	amino acid
CMCT_RS04430	COG1760	l-serine dehydratase
CMCT_RS04435	COG1252	NADH dehydrogenase
CMCT_RS04450	COG1028	Short-chain dehydrogenase reductase Sdr
CMCT_RS04465	COG0167	dihydroorotate dehydrogenase activity
CMCT_RS04470	COG1132	(ABC) transporter
CMCT_RS04480	COG0728	peptidoglycan biosynthetic process
CMCT_RS04495	COG1181	Belongs to the D-alanine--D-alanine ligase family
CMCT_RS04510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CMCT_RS04520	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMCT_RS04525	COG0280	phosphate acetyltransferase
CMCT_RS04545	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CMCT_RS04560	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CMCT_RS04565	COG0612	Peptidase, M16
CMCT_RS04580	COG1131	(ABC) transporter
CMCT_RS04590	COG4771	TonB-dependent receptor
CMCT_RS04595	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CMCT_RS04630	COG0492	ferredoxin-NADP+ reductase activity
CMCT_RS04640	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CMCT_RS04650	COG2962	Rard protein
CMCT_RS04670	COG1271	oxidase subunit
CMCT_RS04675	COG1294	oxidase, subunit
CMCT_RS04685	COG0440	acetolactate synthase activity
CMCT_RS04690	COG0028	Belongs to the TPP enzyme family
CMCT_RS04695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CMCT_RS04700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CMCT_RS04705	COG0805	protein transport
CMCT_RS04710	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CMCT_RS04725	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CMCT_RS04735	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CMCT_RS04740	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CMCT_RS04745	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CMCT_RS04750	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CMCT_RS04755	COG0542	response to heat
CMCT_RS04760	COG0793	Belongs to the peptidase S41A family
CMCT_RS04770	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMCT_RS04775	COG0047	phosphoribosylformylglycinamidine synthase activity
CMCT_RS04785	COG0204	Acyl-transferase
CMCT_RS04800	COG0326	Molecular chaperone. Has ATPase activity
CMCT_RS04805	COG1704	LemA family
CMCT_RS04840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CMCT_RS04845	COG0552	protein localization to endoplasmic reticulum
CMCT_RS04860	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CMCT_RS04885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CMCT_RS04890	COG0470	DNA polymerase III
CMCT_RS04900	COG0527	aspartate kinase activity
CMCT_RS04905	COG0494	nUDIX hydrolase
CMCT_RS04915	COG3041	Addiction module toxin RelE StbE family
CMCT_RS04925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CMCT_RS04930	COG0582	viral genome integration into host DNA
CMCT_RS04935	COG0772	Belongs to the SEDS family
CMCT_RS04940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CMCT_RS04950	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CMCT_RS04955	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CMCT_RS04960	COG0750	zinc metalloprotease
CMCT_RS04975	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CMCT_RS04985	COG0802	atpase or kinase
CMCT_RS04990	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CMCT_RS04995	COG0137	argininosuccinate synthase activity
CMCT_RS05010	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CMCT_RS05035	COG4964	Belongs to the GSP D family
CMCT_RS05055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CMCT_RS05060	COG1459	type II secretion system
CMCT_RS05070	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CMCT_RS05105	COG4773	Receptor
CMCT_RS05110	COG1979	alcohol dehydrogenase
CMCT_RS05120	COG0110	maltose O-acetyltransferase activity
CMCT_RS05135	COG2207	Transcriptional regulator
CMCT_RS05145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CMCT_RS05155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMCT_RS05160	COG1757	Na H antiporter
CMCT_RS05175	COG1049	propionate catabolic process, 2-methylcitrate cycle
CMCT_RS05185	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CMCT_RS05210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CMCT_RS05230	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CMCT_RS05230	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CMCT_RS05235	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CMCT_RS05240	COG0849	cell division
CMCT_RS05245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CMCT_RS05275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CMCT_RS05280	COG1683	Conserved Protein
CMCT_RS05290	COG0629	single-stranded DNA binding
CMCT_RS05295	COG0360	Binds together with S18 to 16S ribosomal RNA
CMCT_RS05305	COG0557	exoribonuclease II activity
CMCT_RS05320	COG2861	carbohydrate metabolic process
CMCT_RS05330	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CMCT_RS05340	COG2121	Domain of unknown function (DUF374)
CMCT_RS05355	COG2089	acid synthase
CMCT_RS05380	COG0195	Participates in both transcription termination and antitermination
CMCT_RS05385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CMCT_RS05390	COG0612	Peptidase, M16
CMCT_RS05395	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CMCT_RS05455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CMCT_RS05480	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CMCT_RS05535	COG0037	tRNA processing
CMCT_RS05540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CMCT_RS05550	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CMCT_RS05555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CMCT_RS05560	COG0556	nucleotide-excision repair
CMCT_RS05570	COG0556	nucleotide-excision repair
CMCT_RS05585	COG0556	nucleotide-excision repair
CMCT_RS05605	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CMCT_RS05610	COG1045	serine acetyltransferase
CMCT_RS05630	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CMCT_RS05635	COG1966	Carbon starvation protein
CMCT_RS05665	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CMCT_RS05670	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CMCT_RS05675	COG1862	Preprotein translocase
CMCT_RS05680	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CMCT_RS05685	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CMCT_RS05690	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CMCT_RS05710	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CMCT_RS05720	COG1442	glycosyl transferase family 8
CMCT_RS05720	COG1216	Glycosyl transferase, family 2
CMCT_RS05725	COG2089	acid synthase
CMCT_RS05735	COG1083	cytidylyl-transferase
CMCT_RS05750	COG1132	(ABC) transporter
CMCT_RS05755	COG0463	Glycosyl transferase, family 2
CMCT_RS05770	COG1442	glycosyl transferase family 8
CMCT_RS05770	COG1216	Glycosyl transferase, family 2
CMCT_RS05785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CMCT_RS05790	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CMCT_RS05800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CMCT_RS05810	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CMCT_RS05830	COG0494	nUDIX hydrolase
CMCT_RS05840	COG0741	lytic transglycosylase activity
CMCT_RS05840	COG1196	nuclear chromosome segregation
CMCT_RS05840	COG0739	heme binding
CMCT_RS05850	COG1295	ribonuclease BN
CMCT_RS05860	COG0305	Participates in initiation and elongation during chromosome replication
CMCT_RS05870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CMCT_RS05880	COG0539	negative regulation of cytoplasmic translation
CMCT_RS05880	COG1185	polyribonucleotide nucleotidyltransferase activity
CMCT_RS05885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CMCT_RS05905	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CMCT_RS05910	COG0537	adenosine 5'-monophosphoramidase activity
CMCT_RS05915	COG0165	Argininosuccinate lyase
CMCT_RS05925	COG2217	Heavy metal translocating P-type atpase
CMCT_RS05935	COG3153	acetyltransferase
CMCT_RS05945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CMCT_RS05950	COG1301	dicarboxylic acid transport
CMCT_RS05960	COG4591	ABC-type transport system involved in lipoprotein release permease component
CMCT_RS05980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CMCT_RS06015	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CMCT_RS06020	COG1959	2 iron, 2 sulfur cluster binding
CMCT_RS06025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CMCT_RS06030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CMCT_RS06035	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CMCT_RS06040	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CMCT_RS06065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CMCT_RS06080	COG0681	Belongs to the peptidase S26 family
CMCT_RS06085	COG1994	Peptidase M50
CMCT_RS06090	COG0698	ribose 5-phosphate isomerase
CMCT_RS06105	COG0586	Pfam SNARE associated Golgi protein
CMCT_RS06110	COG1028	Short-chain dehydrogenase reductase Sdr
CMCT_RS06115	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CMCT_RS06125	COG0012	GTP binding
CMCT_RS06130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CMCT_RS06165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CMCT_RS06170	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CMCT_RS06180	COG0840	transmembrane signaling receptor activity
CMCT_RS06190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CMCT_RS06190	COG1333	cytochrome c biogenesis protein
CMCT_RS06195	COG0840	transmembrane signaling receptor activity
CMCT_RS06205	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CMCT_RS06215	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMCT_RS06220	COG2249	NAD(P)H dehydrogenase (quinone) activity
CMCT_RS06235	COG0706	membrane insertase activity
CMCT_RS06250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CMCT_RS06275	COG0824	Thioesterase
CMCT_RS06295	COG0501	Belongs to the peptidase M48B family
CMCT_RS06300	COG0733	neurotransmitter:sodium symporter activity
CMCT_RS06305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CMCT_RS06320	COG0733	neurotransmitter:sodium symporter activity
CMCT_RS06325	COG0534	Mate efflux family protein
CMCT_RS06330	COG2271	Major facilitator Superfamily
CMCT_RS06345	COG2358	TRAP transporter, solute receptor (TAXI family
CMCT_RS06355	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CMCT_RS06360	COG2957	Belongs to the agmatine deiminase family
CMCT_RS06370	COG0765	amino acid transport
CMCT_RS06375	COG4215	(ABC) transporter
CMCT_RS06380	COG1126	abc transporter atp-binding protein
CMCT_RS06390	COG2194	sulfuric ester hydrolase activity
CMCT_RS06425	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CMCT_RS06435	COG0768	penicillin binding
CMCT_RS06445	COG1558	bacterial-type flagellum-dependent cell motility
CMCT_RS06450	COG1815	bacterial-type flagellum-dependent cell motility
CMCT_RS06480	COG0210	DNA helicase
CMCT_RS06485	COG1555	photosystem II stabilization
CMCT_RS06485	COG1596	polysaccharide export
CMCT_RS06510	COG0228	four-way junction DNA binding
CMCT_RS06515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CMCT_RS06520	COG0564	pseudouridine synthase activity
CMCT_RS06525	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CMCT_RS06525	COG1519	Transferase
CMCT_RS06535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CMCT_RS06550	COG0640	Transcriptional regulator
CMCT_RS06565	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CMCT_RS06580	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CMCT_RS06585	COG0174	glutamine synthetase
CMCT_RS06615	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CMCT_RS06625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMCT_RS06650	COG0772	Belongs to the SEDS family
CMCT_RS06655	COG0564	pseudouridine synthase activity
CMCT_RS06665	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CMCT_RS06670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CMCT_RS06685	COG0528	UMP kinase activity
CMCT_RS06695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CMCT_RS06700	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CMCT_RS06705	COG2070	2-Nitropropane dioxygenase
CMCT_RS06710	COG0860	N-Acetylmuramoyl-L-alanine amidase
CMCT_RS06715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CMCT_RS06715	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CMCT_RS06755	COG2814	Major facilitator Superfamily
CMCT_RS06765	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMCT_RS06775	COG2171	N-acyltransferase activity
CMCT_RS06780	COG4771	TonB-dependent receptor
CMCT_RS06780	COG1629	transport
CMCT_RS06800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CMCT_RS06805	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CMCT_RS06840	COG0587	DNA-directed DNA polymerase activity
CMCT_RS06845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CMCT_RS06850	COG0724	RNA recognition motif
CMCT_RS06915	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMCT_RS06920	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CMCT_RS06925	COG0149	triose-phosphate isomerase activity
CMCT_RS06930	COG0126	phosphoglycerate kinase activity
CMCT_RS06935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CMCT_RS06945	COG0799	negative regulation of ribosome biogenesis
CMCT_RS06960	COG1611	Belongs to the LOG family
CMCT_RS06965	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CMCT_RS06965	COG1776	CheC inhibitor of MCP methylation
CMCT_RS06970	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CMCT_RS06985	COG0455	bacterial-type flagellum organization
CMCT_RS06990	COG1419	protein localization to endoplasmic reticulum
CMCT_RS06995	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CMCT_RS07000	COG0006	proline dipeptidase activity
CMCT_RS07005	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CMCT_RS07010	COG0402	S-adenosylhomocysteine deaminase activity
CMCT_RS07015	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CMCT_RS07015	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CMCT_RS07025	COG0779	Required for maturation of 30S ribosomal subunits
CMCT_RS07045	COG0083	homoserine kinase activity
CMCT_RS07065	COG0287	Prephenate dehydrogenase
CMCT_RS07070	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CMCT_RS07075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CMCT_RS07075	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CMCT_RS07090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CMCT_RS07095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CMCT_RS07100	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CMCT_RS07140	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CMCT_RS07150	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CMCT_RS07165	COG1192	Involved in chromosome partitioning
CMCT_RS07170	COG1475	DNA binding
CMCT_RS07175	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CMCT_RS07195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CMCT_RS07200	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CMCT_RS07210	COG0811	peptide transport
CMCT_RS07215	COG0848	biopolymer transport protein
CMCT_RS07225	COG0823	Involved in the tonB-independent uptake of proteins
CMCT_RS07240	COG1047	Peptidyl-prolyl cis-trans
CMCT_RS07245	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CMCT_RS07250	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CMCT_RS07255	COG0037	tRNA processing
CMCT_RS07260	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CMCT_RS07265	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CMCT_RS07270	COG3306	glycosyltransferase involved in LPS biosynthesis
CMCT_RS07275	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CMCT_RS07290	COG0500	methyltransferase
CMCT_RS07300	COG0105	UTP biosynthetic process
CMCT_RS07310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CMCT_RS07320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CMCT_RS07330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CMCT_RS07345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CMCT_RS07360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CMCT_RS07365	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CMCT_RS07370	COG0493	'glutamate synthase
CMCT_RS07375	COG0070	glutamate synthase
CMCT_RS07375	COG0067	glutamate synthase
CMCT_RS07375	COG0069	glutamate synthase activity
CMCT_RS07390	COG1921	L-seryl-tRNASec selenium transferase activity
CMCT_RS07410	COG2814	Major facilitator Superfamily
CMCT_RS07415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CMCT_RS07420	COG2081	HI0933 family
CMCT_RS07435	COG0303	'Molybdopterin
CMCT_RS07445	COG0314	molybdopterin synthase activity
CMCT_RS07465	COG0280	phosphate acetyltransferase
CMCT_RS07465	COG0281	malic enzyme
CMCT_RS07475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CMCT_RS07505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CMCT_RS07510	COG1473	amidohydrolase
CMCT_RS07515	COG3340	Belongs to the peptidase S51 family
CMCT_RS07520	COG3069	C4-dicarboxylate transmembrane transporter activity
CMCT_RS07525	COG2195	Cleaves the N-terminal amino acid of tripeptides
CMCT_RS07550	COG5001	Diguanylate cyclase
CMCT_RS07550	COG3300	MHYT domain
CMCT_RS07570	COG1607	acyl-coa hydrolase
CMCT_RS07580	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CMCT_RS07590	COG0437	4 iron, 4 sulfur cluster binding
CMCT_RS07615	COG0243	molybdopterin cofactor binding
CMCT_RS07620	COG3383	formate dehydrogenase (NAD+) activity
CMCT_RS07625	COG0437	4 iron, 4 sulfur cluster binding
CMCT_RS07645	COG1136	(ABC) transporter
CMCT_RS07670	COG0672	)-iron permease
CMCT_RS07675	COG0248	Ppx GppA phosphatase
CMCT_RS07680	COG0642	Histidine kinase
CMCT_RS07695	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CMCT_RS07710	COG0450	alkyl hydroperoxide reductase
CMCT_RS07720	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CMCT_RS07720	COG1776	CheC inhibitor of MCP methylation
CMCT_RS07735	COG0133	tryptophan synthase activity
CMCT_RS07770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CMCT_RS07785	COG1104	cysteine desulfurase activity
CMCT_RS07800	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CMCT_RS07815	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CMCT_RS07820	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CMCT_RS07825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CMCT_RS07845	COG1157	protein secretion by the type III secretion system
CMCT_RS07850	COG0302	gtp cyclohydrolase
CMCT_RS07860	COG0740	serine-type endopeptidase activity
CMCT_RS07880	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CMCT_RS07880	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CMCT_RS07885	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CMCT_RS07950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CMCT_RS07955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CMCT_RS07970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMCT_RS07975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CMCT_RS08015	COG0747	negative chemotaxis
CMCT_RS08020	COG0601	transmembrane transport
CMCT_RS08025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMCT_RS08030	COG0444	Belongs to the ABC transporter superfamily
CMCT_RS08040	COG0251	oxidation-reduction process
CMCT_RS08055	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CMCT_RS08070	COG1253	flavin adenine dinucleotide binding
CMCT_RS08075	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CMCT_RS08085	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CMCT_RS08105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CMCT_RS08120	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CMCT_RS08140	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CMCT_RS08145	COG0723	plastoquinol--plastocyanin reductase activity
CMCT_RS08155	COG2855	membrane
CMCT_RS08180	COG1684	flagellar biosynthetic protein fliR
CMCT_RS08185	COG1136	(ABC) transporter
CMCT_RS08190	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CMCT_RS08195	COG0052	Belongs to the universal ribosomal protein uS2 family
CMCT_RS08210	COG0482	sulfurtransferase activity
CMCT_RS08215	COG0358	DNA primase activity
CMCT_RS08245	COG0840	transmembrane signaling receptor activity
CMCT_RS08270	COG0315	cyclic pyranopterin monophosphate synthase activity
CMCT_RS08275	COG0659	secondary active sulfate transmembrane transporter activity
CMCT_RS08315	COG3383	formate dehydrogenase (NAD+) activity
CMCT_RS08320	COG3383	formate dehydrogenase (NAD+) activity
CMCT_RS08330	COG0745	RESPONSE REGULATOR receiver
CMCT_RS08370	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CMCT_RS08375	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CMCT_RS08395	COG0556	nucleotide-excision repair
CMCT_RS08410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CMCT_RS08420	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CMCT_RS08425	COG0708	Exodeoxyribonuclease III
CMCT_RS08435	COG0848	biopolymer transport protein
CMCT_RS08440	COG0811	peptide transport
CMCT_RS08445	COG1629	transport
CMCT_RS08445	COG4206	TonB-dependent receptor
CMCT_RS08455	COG3842	ATPase activity
CMCT_RS08465	COG1840	ABC-type Fe3 transport system, periplasmic component
CMCT_RS08490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CMCT_RS08495	COG1121	(ABC) transporter
CMCT_RS08520	COG1858	cytochrome C peroxidase
CMCT_RS08525	COG3287	FIST C domain
CMCT_RS08525	COG2200	EAL domain
CMCT_RS08525	COG2199	diguanylate cyclase activity
CMCT_RS08535	COG0318	PFAM AMP-dependent synthetase and ligase
CMCT_RS08545	COG0024	Methionine aminopeptidase
CMCT_RS08550	COG0201	protein transport
CMCT_RS08555	COG0200	Binds to the 23S rRNA
CMCT_RS08565	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CMCT_RS08575	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CMCT_RS08580	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMCT_RS08585	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CMCT_RS08590	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CMCT_RS08605	COG0255	Belongs to the universal ribosomal protein uL29 family
CMCT_RS08615	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CMCT_RS08625	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CMCT_RS08630	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CMCT_RS08640	COG0088	Forms part of the polypeptide exit tunnel
CMCT_RS08645	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CMCT_RS08650	COG0051	transcription antitermination factor activity, RNA binding
CMCT_RS08655	COG0439	Biotin carboxylase
CMCT_RS08670	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CMCT_RS08675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CMCT_RS08680	COG0268	Binds directly to 16S ribosomal RNA
CMCT_RS08685	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CMCT_RS08710	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CMCT_RS08715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CMCT_RS08720	COG0765	amino acid transport
CMCT_RS08730	COG0626	cystathionine gamma-synthase activity
CMCT_RS08760	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CMCT_RS08765	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CMCT_RS08775	COG1749	Flagellar hook protein flgE
CMCT_RS08780	COG2056	Na+-H+ antiporter family
CMCT_RS08805	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CMCT_RS08810	COG0352	thiamine-phosphate diphosphorylase activity
CMCT_RS08815	COG0670	Belongs to the BI1 family
CMCT_RS08825	COG0697	spore germination
CMCT_RS08830	COG4750	Nucleotidyl transferase
CMCT_RS08835	COG3475	LICD family
CMCT_RS08840	COG0288	reversible hydration of carbon dioxide
CMCT_RS08845	COG0668	transmembrane transport
CMCT_RS08855	COG2203	Gaf domain
CMCT_RS08855	COG2199	diguanylate cyclase activity
CMCT_RS08860	COG2203	Gaf domain
CMCT_RS08860	COG2199	diguanylate cyclase activity
CMCT_RS08865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CMCT_RS08870	COG0628	permease
CMCT_RS08885	COG2255	four-way junction helicase activity
CMCT_RS08920	COG3210	domain, Protein
CMCT_RS08970	COG3210	domain, Protein
CMCT_RS08975	COG2831	hemolysin activation secretion protein
CMCT_RS09045	COG3290	protein histidine kinase activity
CMCT_RS09045	COG0840	transmembrane signaling receptor activity
CMCT_RS09055	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CMCT_RS09085	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CMCT_RS09090	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CMCT_RS09110	COG0203	ribosomal protein L17
CMCT_RS09115	COG2116	formate transmembrane transporter activity
CMCT_RS09150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CMCT_RS09160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMCT_RS09165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMCT_RS09190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CMCT_RS09195	COG1028	Short-chain dehydrogenase reductase Sdr
CMCT_RS09205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity