locus-tag	class	description
CPIN18021_RS00010	COG0592	DNA-directed DNA polymerase activity
CPIN18021_RS00015	COG0187	DNA topoisomerase II activity
CPIN18021_RS00050	COG1187	pseudouridine synthase activity
CPIN18021_RS00055	COG0517	IMP dehydrogenase activity
CPIN18021_RS00055	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CPIN18021_RS00060	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CPIN18021_RS00095	COG0564	pseudouridine synthase activity
CPIN18021_RS00100	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CPIN18021_RS00115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CPIN18021_RS00130	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CPIN18021_RS00130	COG1328	CTP reductase activity
CPIN18021_RS00140	COG0803	Belongs to the bacterial solute-binding protein 9 family
CPIN18021_RS00145	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CPIN18021_RS00150	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CPIN18021_RS00155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CPIN18021_RS00165	COG1629	transport
CPIN18021_RS00165	COG4206	TonB-dependent receptor
CPIN18021_RS00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CPIN18021_RS00175	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CPIN18021_RS00195	COG1151	hydroxylamine reductase activity
CPIN18021_RS00205	COG0672	)-iron permease
CPIN18021_RS00230	COG0577	efflux transmembrane transporter activity
CPIN18021_RS00230	COG1136	(ABC) transporter
CPIN18021_RS00245	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CPIN18021_RS00250	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CPIN18021_RS00255	COG1335	isochorismatase
CPIN18021_RS00275	COG2353	YceI-like domain
CPIN18021_RS00280	COG1157	protein secretion by the type III secretion system
CPIN18021_RS00295	COG0740	serine-type endopeptidase activity
CPIN18021_RS00305	COG0242	peptide deformylase activity
CPIN18021_RS00315	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CPIN18021_RS00315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CPIN18021_RS00320	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CPIN18021_RS00330	COG0861	Integral membrane protein TerC family
CPIN18021_RS00350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CPIN18021_RS00355	COG1160	GTP binding
CPIN18021_RS00380	COG0284	orotidine-5'-phosphate decarboxylase activity
CPIN18021_RS00385	COG1122	ATPase activity
CPIN18021_RS00435	COG0439	Biotin carboxylase
CPIN18021_RS00440	COG0511	ligase activity, forming carbon-carbon bonds
CPIN18021_RS00445	COG0717	Belongs to the dCTP deaminase family
CPIN18021_RS00450	COG1086	Polysaccharide biosynthesis protein
CPIN18021_RS00455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CPIN18021_RS00460	COG1083	cytidylyl-transferase
CPIN18021_RS00465	COG3980	spore coat polysaccharide biosynthesis protein
CPIN18021_RS00470	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CPIN18021_RS00480	COG0051	transcription antitermination factor activity, RNA binding
CPIN18021_RS00485	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CPIN18021_RS00490	COG0088	Forms part of the polypeptide exit tunnel
CPIN18021_RS00500	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CPIN18021_RS00505	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CPIN18021_RS00515	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CPIN18021_RS00540	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CPIN18021_RS00555	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CPIN18021_RS00560	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CPIN18021_RS00575	COG0200	Binds to the 23S rRNA
CPIN18021_RS00580	COG0201	protein transport
CPIN18021_RS00585	COG0024	Methionine aminopeptidase
CPIN18021_RS00590	COG0840	transmembrane signaling receptor activity
CPIN18021_RS00595	COG0840	transmembrane signaling receptor activity
CPIN18021_RS00595	COG3290	protein histidine kinase activity
CPIN18021_RS00600	COG1749	Flagellar hook protein flgE
CPIN18021_RS00605	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CPIN18021_RS00615	COG0575	Belongs to the CDS family
CPIN18021_RS00640	COG2089	acid synthase
CPIN18021_RS00655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CPIN18021_RS00670	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CPIN18021_RS00695	COG0460	homoserine dehydrogenase
CPIN18021_RS00700	COG0792	nuclease activity
CPIN18021_RS00705	COG3118	belongs to the thioredoxin family
CPIN18021_RS00715	COG0492	ferredoxin-NADP+ reductase activity
CPIN18021_RS00725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CPIN18021_RS00730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CPIN18021_RS00735	COG1028	Short-chain dehydrogenase reductase Sdr
CPIN18021_RS00745	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CPIN18021_RS00765	COG1696	Membrane protein involved in D-alanine export
CPIN18021_RS00770	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CPIN18021_RS00785	COG1049	propionate catabolic process, 2-methylcitrate cycle
CPIN18021_RS00800	COG1757	Na H antiporter
CPIN18021_RS00805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CPIN18021_RS00810	COG1832	CoA-binding protein
CPIN18021_RS00815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CPIN18021_RS00825	COG2906	2 iron, 2 sulfur cluster binding
CPIN18021_RS00825	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CPIN18021_RS00825	COG0822	iron-sulfur transferase activity
CPIN18021_RS00835	COG0840	transmembrane signaling receptor activity
CPIN18021_RS00840	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CPIN18021_RS00845	COG1987	bacterial-type flagellum assembly
CPIN18021_RS00860	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CPIN18021_RS00865	COG0642	Histidine kinase
CPIN18021_RS00870	COG0745	RESPONSE REGULATOR receiver
CPIN18021_RS00875	COG0488	(ABC) transporter
CPIN18021_RS00880	COG0488	(ABC) transporter
CPIN18021_RS00885	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CPIN18021_RS00900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CPIN18021_RS00905	COG1045	serine acetyltransferase
CPIN18021_RS00950	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CPIN18021_RS00955	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CPIN18021_RS00960	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CPIN18021_RS00965	COG2194	sulfuric ester hydrolase activity
CPIN18021_RS00970	COG0583	DNA-binding transcription factor activity
CPIN18021_RS00975	COG1053	succinate dehydrogenase
CPIN18021_RS00980	COG1053	succinate dehydrogenase
CPIN18021_RS00990	COG3005	denitrification pathway
CPIN18021_RS01005	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CPIN18021_RS01010	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CPIN18021_RS01030	COG0203	ribosomal protein L17
CPIN18021_RS01035	COG0748	coenzyme F420 binding
CPIN18021_RS01045	COG0741	lytic transglycosylase activity
CPIN18021_RS01045	COG1196	nuclear chromosome segregation
CPIN18021_RS01045	COG0739	heme binding
CPIN18021_RS01050	COG2239	Acts as a magnesium transporter
CPIN18021_RS01065	COG3383	formate dehydrogenase (NAD+) activity
CPIN18021_RS01070	COG3383	formate dehydrogenase (NAD+) activity
CPIN18021_RS01080	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CPIN18021_RS01080	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CPIN18021_RS01100	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CPIN18021_RS01105	COG4615	Cyclic peptide transporter
CPIN18021_RS01145	COG1793	dna ligase
CPIN18021_RS01155	COG0746	molybdenum cofactor guanylyltransferase activity
CPIN18021_RS01170	COG1966	Carbon starvation protein
CPIN18021_RS01180	COG0003	Pfam Anion-transporting ATPase
CPIN18021_RS01325	COG4974	Belongs to the 'phage' integrase family
CPIN18021_RS01395	COG0582	viral genome integration into host DNA
CPIN18021_RS01755	COG0629	single-stranded DNA binding
CPIN18021_RS01775	COG3646	Phage regulatory protein
CPIN18021_RS01785	COG0582	viral genome integration into host DNA
CPIN18021_RS01800	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CPIN18021_RS01810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CPIN18021_RS01815	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPIN18021_RS01820	COG0651	ATP synthesis coupled electron transport
CPIN18021_RS01825	COG0650	Formate hydrogenlyase subunit 4
CPIN18021_RS01830	COG4237	Hydrogenase 4 membrane
CPIN18021_RS01835	COG0651	ATP synthesis coupled electron transport
CPIN18021_RS01840	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CPIN18021_RS01840	COG3261	NADH dehydrogenase
CPIN18021_RS01850	COG3260	NADH ubiquinone oxidoreductase 20
CPIN18021_RS01865	COG2116	formate transmembrane transporter activity
CPIN18021_RS01875	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CPIN18021_RS01900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CPIN18021_RS01905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CPIN18021_RS01910	COG1074	ATP-dependent DNA helicase activity
CPIN18021_RS01935	COG2010	Cytochrome c
CPIN18021_RS01950	COG3278	Belongs to the heme-copper respiratory oxidase family
CPIN18021_RS01970	COG0505	Belongs to the CarA family
CPIN18021_RS01985	COG0745	RESPONSE REGULATOR receiver
CPIN18021_RS02005	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CPIN18021_RS02025	COG0105	UTP biosynthetic process
CPIN18021_RS02035	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CPIN18021_RS02045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CPIN18021_RS02055	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CPIN18021_RS02060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CPIN18021_RS02070	COG0424	maF-like protein
CPIN18021_RS02080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CPIN18021_RS02085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CPIN18021_RS02105	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CPIN18021_RS02110	COG0049	tRNA binding
CPIN18021_RS02115	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CPIN18021_RS02120	COG1309	transcriptional regulator
CPIN18021_RS02130	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CPIN18021_RS02145	COG0754	glutathionylspermidine amidase activity
CPIN18021_RS02150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPIN18021_RS02155	COG1666	GTP binding
CPIN18021_RS02160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CPIN18021_RS02185	COG0437	4 iron, 4 sulfur cluster binding
CPIN18021_RS02190	COG0348	domain, Protein
CPIN18021_RS02195	COG3043	anaerobic respiration
CPIN18021_RS02215	COG0783	Belongs to the Dps family
CPIN18021_RS02235	COG0546	phosphoglycolate phosphatase activity
CPIN18021_RS02250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPIN18021_RS02255	COG0577	efflux transmembrane transporter activity
CPIN18021_RS02255	COG1136	(ABC) transporter
CPIN18021_RS02275	COG2205	protein histidine kinase activity
CPIN18021_RS02280	COG0745	RESPONSE REGULATOR receiver
CPIN18021_RS02285	COG3301	Polysulphide reductase, NrfD
CPIN18021_RS02290	COG0437	4 iron, 4 sulfur cluster binding
CPIN18021_RS02295	COG0243	molybdopterin cofactor binding
CPIN18021_RS02310	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CPIN18021_RS02315	COG0237	dephospho-CoA kinase activity
CPIN18021_RS02320	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CPIN18021_RS02330	COG1580	Controls the rotational direction of flagella during chemotaxis
CPIN18021_RS02355	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CPIN18021_RS02360	COG0142	geranyltranstransferase activity
CPIN18021_RS02370	COG0546	phosphoglycolate phosphatase activity
CPIN18021_RS02380	COG1749	Flagellar hook protein flgE
CPIN18021_RS02395	COG1217	gtp-binding protein TYPA
CPIN18021_RS02410	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CPIN18021_RS02415	COG2252	PERMEase
CPIN18021_RS02420	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CPIN18021_RS02430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CPIN18021_RS02450	COG1024	Enoyl-CoA hydratase
CPIN18021_RS02460	COG0657	acetylesterase activity
CPIN18021_RS02470	COG1960	acyl-CoA dehydrogenase activity
CPIN18021_RS02475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CPIN18021_RS02480	COG0318	PFAM AMP-dependent synthetase and ligase
CPIN18021_RS02485	COG0644	oxidoreductase
CPIN18021_RS02490	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CPIN18021_RS02530	COG0280	phosphate acetyltransferase
CPIN18021_RS02530	COG0281	malic enzyme
CPIN18021_RS02560	COG1793	dna ligase
CPIN18021_RS02570	COG0746	molybdenum cofactor guanylyltransferase activity
CPIN18021_RS02590	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CPIN18021_RS02595	COG0731	radical SAM domain protein
CPIN18021_RS02610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CPIN18021_RS02615	COG0804	urea catabolic process
CPIN18021_RS02620	COG0832	Belongs to the urease beta subunit family
CPIN18021_RS02620	COG0831	urea catabolic process
CPIN18021_RS02625	COG0831	urea catabolic process
CPIN18021_RS02630	COG0829	nickel cation binding
CPIN18021_RS02640	COG0830	nickel cation binding
CPIN18021_RS02645	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CPIN18021_RS02650	COG1733	regulation of RNA biosynthetic process
CPIN18021_RS02655	COG1979	alcohol dehydrogenase
CPIN18021_RS02665	COG0778	Nitroreductase
CPIN18021_RS02720	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPIN18021_RS02720	COG4624	Iron only hydrogenase large subunit, C-terminal domain
CPIN18021_RS02735	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CPIN18021_RS02740	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CPIN18021_RS02750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CPIN18021_RS02760	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CPIN18021_RS02765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPIN18021_RS02770	COG1120	ATPase activity
CPIN18021_RS02775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CPIN18021_RS02780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CPIN18021_RS02800	COG1136	(ABC) transporter
CPIN18021_RS02805	COG1684	flagellar biosynthetic protein fliR
CPIN18021_RS02815	COG0194	GDP metabolic process
CPIN18021_RS02820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CPIN18021_RS02830	COG2855	membrane
CPIN18021_RS02840	COG0723	plastoquinol--plastocyanin reductase activity
CPIN18021_RS02845	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CPIN18021_RS02890	COG0484	heat shock protein binding
CPIN18021_RS02905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CPIN18021_RS02905	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CPIN18021_RS02915	COG0174	glutamine synthetase
CPIN18021_RS02925	COG0826	peptidase U32
CPIN18021_RS02930	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CPIN18021_RS02945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CPIN18021_RS02955	COG1519	Transferase
CPIN18021_RS02960	COG0564	pseudouridine synthase activity
CPIN18021_RS02965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CPIN18021_RS02970	COG0228	four-way junction DNA binding
CPIN18021_RS02975	COG1837	Belongs to the UPF0109 family
CPIN18021_RS02990	COG0335	large ribosomal subunit rRNA binding
CPIN18021_RS02995	COG4773	Receptor
CPIN18021_RS03015	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CPIN18021_RS03025	COG0745	RESPONSE REGULATOR receiver
CPIN18021_RS03050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CPIN18021_RS03055	COG0500	methyltransferase
CPIN18021_RS03060	COG2830	Protein of unknown function (DUF452)
CPIN18021_RS03085	COG4786	Flagellar basal body rod
CPIN18021_RS03090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CPIN18021_RS03105	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CPIN18021_RS03135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CPIN18021_RS03150	COG1181	Belongs to the D-alanine--D-alanine ligase family
CPIN18021_RS03165	COG0728	peptidoglycan biosynthetic process
CPIN18021_RS03175	COG1132	(ABC) transporter
CPIN18021_RS03180	COG0167	dihydroorotate dehydrogenase activity
CPIN18021_RS03195	COG1028	Short-chain dehydrogenase reductase Sdr
CPIN18021_RS03215	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CPIN18021_RS03235	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CPIN18021_RS03240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CPIN18021_RS03245	COG1663	tetraacyldisaccharide 4'-kinase activity
CPIN18021_RS03250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CPIN18021_RS03255	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CPIN18021_RS03325	COG3041	Addiction module toxin RelE StbE family
CPIN18021_RS03340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CPIN18021_RS03345	COG0730	response to heat
CPIN18021_RS03355	COG0210	DNA helicase
CPIN18021_RS03365	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CPIN18021_RS03370	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CPIN18021_RS03385	COG1815	bacterial-type flagellum-dependent cell motility
CPIN18021_RS03390	COG1558	bacterial-type flagellum-dependent cell motility
CPIN18021_RS03395	COG1677	Flagellar hook-basal body complex protein FliE
CPIN18021_RS03400	COG0768	penicillin binding
CPIN18021_RS03430	COG0519	Catalyzes the synthesis of GMP from XMP
CPIN18021_RS03430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CPIN18021_RS03455	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CPIN18021_RS03470	COG1174	glycine betaine transport
CPIN18021_RS03475	COG0799	negative regulation of ribosome biogenesis
CPIN18021_RS03485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CPIN18021_RS03495	COG0149	triose-phosphate isomerase activity
CPIN18021_RS03500	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CPIN18021_RS03505	COG0733	neurotransmitter:sodium symporter activity
CPIN18021_RS03510	COG0534	Mate efflux family protein
CPIN18021_RS03520	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CPIN18021_RS03525	COG0552	protein localization to endoplasmic reticulum
CPIN18021_RS03530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CPIN18021_RS03540	COG1418	mRNA catabolic process
CPIN18021_RS03565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPIN18021_RS03570	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CPIN18021_RS03575	COG0138	bifunctional purine biosynthesis protein purh
CPIN18021_RS03585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CPIN18021_RS03590	COG0612	Peptidase, M16
CPIN18021_RS03595	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CPIN18021_RS03615	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CPIN18021_RS03645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CPIN18021_RS03650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CPIN18021_RS03655	COG0521	Mo-molybdopterin cofactor biosynthetic process
CPIN18021_RS03665	COG0443	Heat shock 70 kDa protein
CPIN18021_RS03675	COG1420	regulation of RNA biosynthetic process
CPIN18021_RS03685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CPIN18021_RS03690	COG0772	Belongs to the SEDS family
CPIN18021_RS03705	COG1166	arginine decarboxylase activity
CPIN18021_RS03710	COG0124	histidyl-tRNA synthetase
CPIN18021_RS03715	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CPIN18021_RS03720	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CPIN18021_RS03725	COG0163	prenyltransferase activity
CPIN18021_RS03745	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CPIN18021_RS03750	COG2833	Protein of unknown function (DUF455)
CPIN18021_RS03770	COG0706	membrane insertase activity
CPIN18021_RS03780	COG0594	ribonuclease P activity
CPIN18021_RS03785	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CPIN18021_RS03800	COG0824	Thioesterase
CPIN18021_RS03830	COG0788	formyltetrahydrofolate deformylase activity
CPIN18021_RS03835	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CPIN18021_RS03840	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CPIN18021_RS03845	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CPIN18021_RS03875	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CPIN18021_RS03875	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CPIN18021_RS03880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPIN18021_RS03885	COG0765	amino acid transport
CPIN18021_RS03905	COG0352	thiamine-phosphate diphosphorylase activity
CPIN18021_RS03915	COG0537	adenosine 5'-monophosphoramidase activity
CPIN18021_RS03920	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CPIN18021_RS03930	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CPIN18021_RS03940	COG1185	polyribonucleotide nucleotidyltransferase activity
CPIN18021_RS03940	COG0539	negative regulation of cytoplasmic translation
CPIN18021_RS03950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CPIN18021_RS03965	COG0305	Participates in initiation and elongation during chromosome replication
CPIN18021_RS03975	COG1295	ribonuclease BN
CPIN18021_RS03980	COG0582	viral genome integration into host DNA
CPIN18021_RS03985	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CPIN18021_RS04005	COG0642	Histidine kinase
CPIN18021_RS04010	COG0165	Argininosuccinate lyase
CPIN18021_RS04020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CPIN18021_RS04030	COG0039	L-malate dehydrogenase activity
CPIN18021_RS04040	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CPIN18021_RS04050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPIN18021_RS04055	COG2011	ABC-type metal ion transport system permease component
CPIN18021_RS04060	COG1464	Belongs to the NlpA lipoprotein family
CPIN18021_RS04065	COG1280	lysine exporter protein (LysE YggA)
CPIN18021_RS04075	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CPIN18021_RS04075	COG2050	protein possibly involved in aromatic compounds catabolism
CPIN18021_RS04085	COG1305	Transglutaminase-like
CPIN18021_RS04095	COG2195	Cleaves the N-terminal amino acid of tripeptides
CPIN18021_RS04100	COG0542	response to heat
CPIN18021_RS04105	COG0793	Belongs to the peptidase S41A family
CPIN18021_RS04110	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CPIN18021_RS04115	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPIN18021_RS04120	COG0047	phosphoribosylformylglycinamidine synthase activity
CPIN18021_RS04130	COG0204	Acyl-transferase
CPIN18021_RS04135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CPIN18021_RS04145	COG2217	Heavy metal translocating P-type atpase
CPIN18021_RS04165	COG3022	response to hydroperoxide
CPIN18021_RS04170	COG0776	regulation of translation
CPIN18021_RS04185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CPIN18021_RS04190	COG2204	response regulator
CPIN18021_RS04220	COG0280	phosphate acetyltransferase
CPIN18021_RS04230	COG0484	heat shock protein binding
CPIN18021_RS04235	COG0789	Transcriptional regulator
CPIN18021_RS04245	COG0587	DNA-directed DNA polymerase activity
CPIN18021_RS04250	COG0724	RNA recognition motif
CPIN18021_RS04255	COG0693	protein deglycase activity
CPIN18021_RS04265	COG0252	asparaginase activity
CPIN18021_RS04275	COG4574	serine-type endopeptidase inhibitor activity
CPIN18021_RS04280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CPIN18021_RS04285	COG2244	polysaccharide biosynthetic process
CPIN18021_RS04295	COG0438	transferase activity, transferring glycosyl groups
CPIN18021_RS04300	COG1215	transferase activity, transferring glycosyl groups
CPIN18021_RS04305	COG0438	transferase activity, transferring glycosyl groups
CPIN18021_RS04315	COG0438	transferase activity, transferring glycosyl groups
CPIN18021_RS04320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CPIN18021_RS04340	COG0501	Belongs to the peptidase M48B family
CPIN18021_RS04345	COG0733	neurotransmitter:sodium symporter activity
CPIN18021_RS04350	COG0617	tRNA 3'-terminal CCA addition
CPIN18021_RS04365	COG0473	3-isopropylmalate dehydrogenase activity
CPIN18021_RS04370	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CPIN18021_RS04380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CPIN18021_RS04385	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CPIN18021_RS04405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CPIN18021_RS04410	COG1301	dicarboxylic acid transport
CPIN18021_RS04415	COG0778	Nitroreductase
CPIN18021_RS04420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CPIN18021_RS04430	COG3340	Belongs to the peptidase S51 family
CPIN18021_RS04435	COG3069	C4-dicarboxylate transmembrane transporter activity
CPIN18021_RS04440	COG2195	Cleaves the N-terminal amino acid of tripeptides
CPIN18021_RS04445	COG2271	Major facilitator Superfamily
CPIN18021_RS04450	COG0733	neurotransmitter:sodium symporter activity
CPIN18021_RS04460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CPIN18021_RS04470	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CPIN18021_RS04475	COG1472	Belongs to the glycosyl hydrolase 3 family
CPIN18021_RS04480	COG1252	NADH dehydrogenase
CPIN18021_RS04485	COG0840	transmembrane signaling receptor activity
CPIN18021_RS04500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CPIN18021_RS04550	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CPIN18021_RS04565	COG0137	argininosuccinate synthase activity
CPIN18021_RS04575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CPIN18021_RS04580	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CPIN18021_RS04585	COG0802	atpase or kinase
CPIN18021_RS04590	COG1137	ATPase activity
CPIN18021_RS04595	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CPIN18021_RS04605	COG0326	Molecular chaperone. Has ATPase activity
CPIN18021_RS04625	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CPIN18021_RS04630	COG0298	carbon dioxide binding
CPIN18021_RS04635	COG0409	Hydrogenase expression formation protein
CPIN18021_RS04640	COG0309	Hydrogenase expression formation protein (HypE)
CPIN18021_RS04645	COG0375	protein maturation
CPIN18021_RS04655	COG0415	Belongs to the DNA photolyase family
CPIN18021_RS04665	COG0440	acetolactate synthase activity
CPIN18021_RS04670	COG0028	Belongs to the TPP enzyme family
CPIN18021_RS04680	COG1674	ftsk spoiiie
CPIN18021_RS04680	COG1196	nuclear chromosome segregation
CPIN18021_RS04710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CPIN18021_RS04730	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CPIN18021_RS04735	COG0628	permease
CPIN18021_RS04755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CPIN18021_RS04760	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CPIN18021_RS04770	COG1496	oxidoreductase activity
CPIN18021_RS04780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CPIN18021_RS04785	COG0268	Binds directly to 16S ribosomal RNA
CPIN18021_RS04825	COG0765	amino acid transport
CPIN18021_RS04830	COG4160	amino acid transport
CPIN18021_RS04835	COG1126	abc transporter atp-binding protein
CPIN18021_RS04840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CPIN18021_RS04845	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CPIN18021_RS04850	COG0849	cell division
CPIN18021_RS04865	COG0275	rRNA processing
CPIN18021_RS04875	COG2046	Belongs to the sulfate adenylyltransferase family
CPIN18021_RS04880	COG0745	RESPONSE REGULATOR receiver
CPIN18021_RS04890	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CPIN18021_RS04895	COG0489	protein tyrosine kinase activity
CPIN18021_RS04950	COG4310	Domain of unknown function (DUF2172)
CPIN18021_RS04975	COG0314	molybdopterin synthase activity
CPIN18021_RS04990	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CPIN18021_RS05000	COG0688	phosphatidylethanolamine metabolic process
CPIN18021_RS05005	COG1408	metallophosphoesterase
CPIN18021_RS05015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CPIN18021_RS05020	COG1116	anion transmembrane transporter activity
CPIN18021_RS05025	COG4771	TonB-dependent receptor
CPIN18021_RS05025	COG1629	transport
CPIN18021_RS05040	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CPIN18021_RS05045	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CPIN18021_RS05060	COG0733	neurotransmitter:sodium symporter activity
CPIN18021_RS05065	COG0733	neurotransmitter:sodium symporter activity
CPIN18021_RS05070	COG0733	neurotransmitter:sodium symporter activity
CPIN18021_RS05075	COG1304	FMN binding
CPIN18021_RS05100	COG1556	Lactate utilization protein
CPIN18021_RS05105	COG1139	Iron-sulfur cluster binding protein
CPIN18021_RS05110	COG0247	lactate metabolic process
CPIN18021_RS05115	COG1620	l-lactate permease
CPIN18021_RS05140	COG1338	Plays a role in the flagellum-specific transport system
CPIN18021_RS05145	COG1360	Flagellar Motor Protein
CPIN18021_RS05160	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CPIN18021_RS05170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CPIN18021_RS05175	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CPIN18021_RS05185	COG0101	tRNA pseudouridine synthase activity
CPIN18021_RS05190	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CPIN18021_RS05195	COG1164	Oligoendopeptidase f
CPIN18021_RS05205	COG1629	transport
CPIN18021_RS05205	COG4771	TonB-dependent receptor
CPIN18021_RS05230	COG3976	FMN-binding domain protein
CPIN18021_RS05230	COG1053	succinate dehydrogenase
CPIN18021_RS05240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CPIN18021_RS05250	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CPIN18021_RS05255	COG2404	hydrolase activity, acting on ester bonds
CPIN18021_RS05285	COG0352	thiamine-phosphate diphosphorylase activity
CPIN18021_RS05290	COG2022	thiamine diphosphate biosynthetic process
CPIN18021_RS05300	COG2171	N-acyltransferase activity
CPIN18021_RS05320	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CPIN18021_RS05350	COG1395	domain, Protein
CPIN18021_RS05365	COG2842	Transposition protein
CPIN18021_RS05590	COG1706	bacterial-type flagellum-dependent cell motility
CPIN18021_RS05595	COG3951	Flagellar rod assembly protein muramidase FlgJ
CPIN18021_RS05620	COG1741	Belongs to the pirin family
CPIN18021_RS05635	COG3383	formate dehydrogenase (NAD+) activity
CPIN18021_RS05640	COG3383	formate dehydrogenase (NAD+) activity
CPIN18021_RS05645	COG0437	4 iron, 4 sulfur cluster binding
CPIN18021_RS05655	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CPIN18021_RS05670	COG0343	queuine tRNA-ribosyltransferase activity
CPIN18021_RS05675	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CPIN18021_RS05680	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CPIN18021_RS05685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CPIN18021_RS05695	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CPIN18021_RS05715	COG0602	queuosine metabolic process
CPIN18021_RS05745	COG0191	fructose-bisphosphate aldolase activity
CPIN18021_RS05750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CPIN18021_RS05755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CPIN18021_RS05765	COG0484	heat shock protein binding
CPIN18021_RS05770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CPIN18021_RS05775	COG0745	RESPONSE REGULATOR receiver
CPIN18021_RS05780	COG0642	Histidine kinase
CPIN18021_RS05790	COG0556	nucleotide-excision repair
CPIN18021_RS05810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CPIN18021_RS05815	COG2201	protein-glutamate methylesterase activity
CPIN18021_RS05820	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CPIN18021_RS05830	COG1333	cytochrome c biogenesis protein
CPIN18021_RS05830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CPIN18021_RS05855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CPIN18021_RS05870	COG0527	aspartate kinase activity
CPIN18021_RS05875	COG0494	nUDIX hydrolase
CPIN18021_RS05880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CPIN18021_RS05885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CPIN18021_RS05890	COG0805	protein transport
CPIN18021_RS05895	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CPIN18021_RS05905	COG1027	Aspartate ammonia-lyase
CPIN18021_RS05910	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CPIN18021_RS05920	COG0616	signal peptide processing
CPIN18021_RS05925	COG0402	S-adenosylhomocysteine deaminase activity
CPIN18021_RS05930	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CPIN18021_RS05935	COG0006	proline dipeptidase activity
CPIN18021_RS05940	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CPIN18021_RS05945	COG1419	protein localization to endoplasmic reticulum
CPIN18021_RS05950	COG0455	bacterial-type flagellum organization
CPIN18021_RS05965	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CPIN18021_RS05970	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CPIN18021_RS05970	COG1776	CheC inhibitor of MCP methylation
CPIN18021_RS05975	COG1611	Belongs to the LOG family
CPIN18021_RS05985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPIN18021_RS05990	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CPIN18021_RS05995	COG4206	TonB-dependent receptor
CPIN18021_RS05995	COG1629	transport
CPIN18021_RS06010	COG0811	peptide transport
CPIN18021_RS06015	COG0848	biopolymer transport protein
CPIN18021_RS06025	COG2151	metal-sulfur cluster biosynthetic enzyme
CPIN18021_RS06040	COG1610	YqeY-like protein
CPIN18021_RS06055	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CPIN18021_RS06075	COG0727	PFAM Uncharacterised protein family (UPF0153)
CPIN18021_RS06080	COG2813	Specifically methylates the guanine in position
CPIN18021_RS06090	COG0492	ferredoxin-NADP+ reductase activity
CPIN18021_RS06095	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CPIN18021_RS06100	COG2962	Rard protein
CPIN18021_RS06110	COG0750	zinc metalloprotease
CPIN18021_RS06115	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CPIN18021_RS06120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CPIN18021_RS06130	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CPIN18021_RS06155	COG2121	Domain of unknown function (DUF374)
CPIN18021_RS06170	COG0195	Participates in both transcription termination and antitermination
CPIN18021_RS06180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CPIN18021_RS06195	COG0708	Exodeoxyribonuclease III
CPIN18021_RS06210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CPIN18021_RS06230	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CPIN18021_RS06235	COG1218	3'(2'),5'-bisphosphate nucleotidase
CPIN18021_RS06240	COG0372	Belongs to the citrate synthase family
CPIN18021_RS06245	COG0569	domain protein
CPIN18021_RS06245	COG0475	glutathione-regulated potassium exporter activity
CPIN18021_RS06250	COG0037	tRNA processing
CPIN18021_RS06255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CPIN18021_RS06265	COG1047	Peptidyl-prolyl cis-trans
CPIN18021_RS06275	COG2885	chlorophyll binding
CPIN18021_RS06290	COG0848	biopolymer transport protein
CPIN18021_RS06295	COG0811	peptide transport
CPIN18021_RS06310	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CPIN18021_RS06315	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CPIN18021_RS06335	COG1475	DNA binding
CPIN18021_RS06340	COG1192	Involved in chromosome partitioning
CPIN18021_RS06345	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CPIN18021_RS06345	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CPIN18021_RS06370	COG1183	phosphatidylcholine synthase activity
CPIN18021_RS06375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CPIN18021_RS06380	COG2264	protein methyltransferase activity
CPIN18021_RS06385	COG0745	RESPONSE REGULATOR receiver
CPIN18021_RS06395	COG1086	Polysaccharide biosynthesis protein
CPIN18021_RS06400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CPIN18021_RS06445	COG0330	HflC and HflK could
CPIN18021_RS06465	COG1970	mechanosensitive ion channel activity
CPIN18021_RS06495	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CPIN18021_RS06505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPIN18021_RS06505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPIN18021_RS06535	COG5001	Diguanylate cyclase
CPIN18021_RS06535	COG3300	MHYT domain
CPIN18021_RS06545	COG5001	Diguanylate cyclase
CPIN18021_RS06545	COG4251	negative regulation of phosphorylation
CPIN18021_RS06545	COG3706	GGDEF domain
CPIN18021_RS06545	COG2203	Gaf domain
CPIN18021_RS06555	COG0497	DNA recombination
CPIN18021_RS06565	COG0084	hydrolase, TatD family'
CPIN18021_RS06575	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CPIN18021_RS06610	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CPIN18021_RS06615	COG0166	Belongs to the GPI family
CPIN18021_RS06625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPIN18021_RS06630	COG4662	Binding-protein-dependent transport system inner membrane component
CPIN18021_RS06635	COG2998	abc-type tungstate transport system, permease component
CPIN18021_RS06640	COG1739	Uncharacterized protein family UPF0029
CPIN18021_RS06655	COG1053	succinate dehydrogenase
CPIN18021_RS06660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CPIN18021_RS06670	COG2257	FlhB HrpN YscU SpaS Family
CPIN18021_RS06710	COG0681	Belongs to the peptidase S26 family
CPIN18021_RS06715	COG1994	Peptidase M50
CPIN18021_RS06720	COG0698	ribose 5-phosphate isomerase
CPIN18021_RS06735	COG0586	Pfam SNARE associated Golgi protein
CPIN18021_RS06740	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CPIN18021_RS06745	COG0012	GTP binding
CPIN18021_RS06760	COG1127	ABC transporter
CPIN18021_RS06765	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CPIN18021_RS06770	COG0439	Biotin carboxylase
CPIN18021_RS06780	COG1921	L-seryl-tRNASec selenium transferase activity
CPIN18021_RS06810	COG0083	homoserine kinase activity
CPIN18021_RS06835	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CPIN18021_RS06840	COG2217	Heavy metal translocating P-type atpase
CPIN18021_RS06910	COG2860	membrane
CPIN18021_RS06915	COG0450	alkyl hydroperoxide reductase
CPIN18021_RS06935	COG1776	CheC inhibitor of MCP methylation
CPIN18021_RS06935	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CPIN18021_RS06945	COG0730	response to heat
CPIN18021_RS06960	COG0859	PFAM glycosyl transferase family 9
CPIN18021_RS06970	COG0463	Glycosyl transferase, family 2
CPIN18021_RS06975	COG0859	PFAM glycosyl transferase family 9
CPIN18021_RS06980	COG0726	polysaccharide deacetylase
CPIN18021_RS06985	COG1216	Glycosyl transferase, family 2
CPIN18021_RS06985	COG1442	glycosyl transferase family 8
CPIN18021_RS06995	COG0859	PFAM glycosyl transferase family 9
CPIN18021_RS07000	COG0438	transferase activity, transferring glycosyl groups
CPIN18021_RS07005	COG0438	transferase activity, transferring glycosyl groups
CPIN18021_RS07030	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CPIN18021_RS07035	COG0085	RNA polymerase activity
CPIN18021_RS07040	COG0222	ribosome binding
CPIN18021_RS07045	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CPIN18021_RS07055	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CPIN18021_RS07060	COG0250	Participates in transcription elongation, termination and antitermination
CPIN18021_RS07075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CPIN18021_RS07080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CPIN18021_RS07115	COG2197	response regulator
CPIN18021_RS07125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPIN18021_RS07150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CPIN18021_RS07160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CPIN18021_RS07165	COG0113	porphobilinogen synthase activity
CPIN18021_RS07170	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CPIN18021_RS07175	COG0357	Ribosomal RNA small subunit methyltransferase G
CPIN18021_RS07190	COG0501	Belongs to the peptidase M48B family
CPIN18021_RS07195	COG0579	oxidoreductase
CPIN18021_RS07200	COG0783	Belongs to the Dps family
CPIN18021_RS07205	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CPIN18021_RS07210	COG2824	Alkylphosphonate utilization operon protein PhnA
CPIN18021_RS07215	COG0772	Belongs to the SEDS family
CPIN18021_RS07220	COG0564	pseudouridine synthase activity
CPIN18021_RS07230	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CPIN18021_RS07235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPIN18021_RS07255	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CPIN18021_RS07260	COG0528	UMP kinase activity
CPIN18021_RS07270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CPIN18021_RS07285	COG0860	N-Acetylmuramoyl-L-alanine amidase
CPIN18021_RS07290	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CPIN18021_RS07290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CPIN18021_RS07330	COG1755	Isoprenylcysteine carboxyl methyltransferase
CPIN18021_RS07340	COG2056	Na+-H+ antiporter family
CPIN18021_RS07375	COG1823	symporter activity
CPIN18021_RS07380	COG0628	permease
CPIN18021_RS07385	COG2255	four-way junction helicase activity
CPIN18021_RS07400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CPIN18021_RS07425	COG1040	competence protein
CPIN18021_RS07430	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CPIN18021_RS07475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CPIN18021_RS07490	COG2861	carbohydrate metabolic process
CPIN18021_RS07505	COG0557	exoribonuclease II activity
CPIN18021_RS07515	COG0360	Binds together with S18 to 16S ribosomal RNA
CPIN18021_RS07520	COG0629	single-stranded DNA binding
CPIN18021_RS07545	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CPIN18021_RS07565	COG0500	methyltransferase
CPIN18021_RS07580	COG1570	exodeoxyribonuclease VII activity
CPIN18021_RS07600	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CPIN18021_RS07610	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CPIN18021_RS07615	COG1766	The M ring may be actively involved in energy transduction
CPIN18021_RS07620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CPIN18021_RS07625	COG0077	Prephenate dehydratase
CPIN18021_RS07625	COG1605	Chorismate mutase
CPIN18021_RS07630	COG0019	diaminopimelate decarboxylase activity
CPIN18021_RS07645	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CPIN18021_RS07655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CPIN18021_RS07660	COG0560	Phosphoserine phosphatase
CPIN18021_RS07665	COG0835	chemotaxis
CPIN18021_RS07670	COG2198	Histidine kinase
CPIN18021_RS07670	COG0643	Histidine kinase
CPIN18021_RS07670	COG0784	Response regulator, receiver
CPIN18021_RS07675	COG0784	Response regulator, receiver
CPIN18021_RS07675	COG0835	chemotaxis
CPIN18021_RS07685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CPIN18021_RS07695	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CPIN18021_RS07705	COG1115	amino acid carrier protein
CPIN18021_RS07710	COG0814	amino acid
CPIN18021_RS07715	COG1760	l-serine dehydratase
CPIN18021_RS07725	COG0243	molybdopterin cofactor binding
CPIN18021_RS07730	COG3383	formate dehydrogenase (NAD+) activity
CPIN18021_RS07735	COG0437	4 iron, 4 sulfur cluster binding
CPIN18021_RS07765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CPIN18021_RS07770	COG2814	Major facilitator Superfamily
CPIN18021_RS07775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPIN18021_RS07775	COG1013	pyruvate-flavodoxin oxidoreductase activity
CPIN18021_RS07775	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CPIN18021_RS07775	COG0674	pyruvate-flavodoxin oxidoreductase activity
CPIN18021_RS07785	COG0778	Nitroreductase
CPIN18021_RS07810	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CPIN18021_RS07815	COG1115	amino acid carrier protein
CPIN18021_RS07820	COG1294	oxidase, subunit
CPIN18021_RS07825	COG1271	oxidase subunit
CPIN18021_RS07835	COG0504	CTP synthase activity
CPIN18021_RS07855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CPIN18021_RS07870	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CPIN18021_RS07875	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CPIN18021_RS07880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CPIN18021_RS07885	COG4968	Prepilin-type N-terminal cleavage methylation domain
CPIN18021_RS07900	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CPIN18021_RS07915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CPIN18021_RS07920	COG1942	4-Oxalocrotonate Tautomerase
CPIN18021_RS07940	COG2831	hemolysin activation secretion protein
CPIN18021_RS07945	COG3210	domain, Protein
CPIN18021_RS07945	COG3210	domain, Protein
CPIN18021_RS07975	COG1979	alcohol dehydrogenase
CPIN18021_RS07990	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CPIN18021_RS08000	COG1696	Membrane protein involved in D-alanine export
CPIN18021_RS08010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CPIN18021_RS08020	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CPIN18021_RS08025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CPIN18021_RS08045	COG4750	Nucleotidyl transferase
CPIN18021_RS08050	COG3475	LICD family
CPIN18021_RS08055	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CPIN18021_RS08055	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CPIN18021_RS08065	COG0243	molybdopterin cofactor binding
CPIN18021_RS08080	COG0243	molybdopterin cofactor binding
CPIN18021_RS08120	COG0716	FMN binding
CPIN18021_RS08125	COG0352	thiamine-phosphate diphosphorylase activity
CPIN18021_RS08130	COG0670	Belongs to the BI1 family
CPIN18021_RS08135	COG0288	reversible hydration of carbon dioxide
CPIN18021_RS08140	COG0668	transmembrane transport
CPIN18021_RS08145	COG3706	GGDEF domain
CPIN18021_RS08150	COG3706	GGDEF domain
CPIN18021_RS08155	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CPIN18021_RS08180	COG0318	PFAM AMP-dependent synthetase and ligase
CPIN18021_RS08185	COG1222	aaa ATPase
CPIN18021_RS08190	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CPIN18021_RS08195	COG0233	cytoplasmic translational termination
CPIN18021_RS08200	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CPIN18021_RS08210	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CPIN18021_RS08215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CPIN18021_RS08230	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CPIN18021_RS08255	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CPIN18021_RS08275	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CPIN18021_RS08310	COG5001	Diguanylate cyclase
CPIN18021_RS08310	COG3300	MHYT domain
CPIN18021_RS08315	COG1193	negative regulation of DNA recombination
CPIN18021_RS08335	COG0519	Catalyzes the synthesis of GMP from XMP
CPIN18021_RS08355	COG2226	methyltransferase
CPIN18021_RS08360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CPIN18021_RS08380	COG2226	methyltransferase
CPIN18021_RS08390	COG2423	ornithine cyclodeaminase activity
CPIN18021_RS08400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CPIN18021_RS08420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CPIN18021_RS08425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CPIN18021_RS08430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CPIN18021_RS08435	COG4310	Domain of unknown function (DUF2172)
CPIN18021_RS08440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CPIN18021_RS08440	COG4797	methyltransferase
CPIN18021_RS08460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CPIN18021_RS08485	COG1981	membrane
CPIN18021_RS08510	COG2199	diguanylate cyclase activity
CPIN18021_RS08510	COG2200	EAL domain
CPIN18021_RS08510	COG3287	FIST C domain
CPIN18021_RS08515	COG1858	cytochrome C peroxidase
CPIN18021_RS08520	COG2264	protein methyltransferase activity
CPIN18021_RS08530	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CPIN18021_RS08580	COG0517	IMP dehydrogenase activity
CPIN18021_RS08580	COG0516	GMP reductase activity
CPIN18021_RS08585	COG0154	amidase activity
CPIN18021_RS08595	COG1546	Belongs to the CinA family
CPIN18021_RS08595	COG1058	Belongs to the CinA family
CPIN18021_RS08610	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CPIN18021_RS08620	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CPIN18021_RS08625	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CPIN18021_RS08630	COG1862	Preprotein translocase
CPIN18021_RS08635	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPIN18021_RS08640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPIN18021_RS08675	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CPIN18021_RS08685	COG1253	flavin adenine dinucleotide binding
CPIN18021_RS08690	COG0251	oxidation-reduction process
CPIN18021_RS08695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPIN18021_RS08715	COG0137	argininosuccinate synthase activity
CPIN18021_RS08720	COG0358	DNA primase activity
CPIN18021_RS08740	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system