locus-tag	class	description
CPIN17261_RS00010	COG0592	DNA-directed DNA polymerase activity
CPIN17261_RS00015	COG0187	DNA topoisomerase II activity
CPIN17261_RS00050	COG1187	pseudouridine synthase activity
CPIN17261_RS00055	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CPIN17261_RS00055	COG0517	IMP dehydrogenase activity
CPIN17261_RS00060	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CPIN17261_RS00090	COG0564	pseudouridine synthase activity
CPIN17261_RS00095	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CPIN17261_RS00100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CPIN17261_RS00105	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CPIN17261_RS00105	COG1328	CTP reductase activity
CPIN17261_RS00115	COG0803	Belongs to the bacterial solute-binding protein 9 family
CPIN17261_RS00125	COG1121	(ABC) transporter
CPIN17261_RS00130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CPIN17261_RS00135	COG0753	catalase activity
CPIN17261_RS00140	COG4206	TonB-dependent receptor
CPIN17261_RS00140	COG1629	transport
CPIN17261_RS00145	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CPIN17261_RS00150	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CPIN17261_RS00175	COG1151	hydroxylamine reductase activity
CPIN17261_RS00185	COG0672	)-iron permease
CPIN17261_RS00210	COG0577	efflux transmembrane transporter activity
CPIN17261_RS00210	COG1136	(ABC) transporter
CPIN17261_RS00225	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CPIN17261_RS00230	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CPIN17261_RS00235	COG1335	isochorismatase
CPIN17261_RS00255	COG2353	YceI-like domain
CPIN17261_RS00260	COG1157	protein secretion by the type III secretion system
CPIN17261_RS00275	COG0740	serine-type endopeptidase activity
CPIN17261_RS00285	COG0242	peptide deformylase activity
CPIN17261_RS00295	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CPIN17261_RS00295	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CPIN17261_RS00300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CPIN17261_RS00345	COG1122	ATPase activity
CPIN17261_RS00350	COG2814	Major facilitator Superfamily
CPIN17261_RS00355	COG0284	orotidine-5'-phosphate decarboxylase activity
CPIN17261_RS00370	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CPIN17261_RS00380	COG1160	GTP binding
CPIN17261_RS00385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CPIN17261_RS00405	COG0861	Integral membrane protein TerC family
CPIN17261_RS00410	COG0840	transmembrane signaling receptor activity
CPIN17261_RS00425	COG0439	Biotin carboxylase
CPIN17261_RS00430	COG0511	ligase activity, forming carbon-carbon bonds
CPIN17261_RS00435	COG0717	Belongs to the dCTP deaminase family
CPIN17261_RS00440	COG1086	Polysaccharide biosynthesis protein
CPIN17261_RS00445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CPIN17261_RS00450	COG1083	cytidylyl-transferase
CPIN17261_RS00455	COG3980	spore coat polysaccharide biosynthesis protein
CPIN17261_RS00460	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CPIN17261_RS00465	COG0051	transcription antitermination factor activity, RNA binding
CPIN17261_RS00470	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CPIN17261_RS00475	COG0088	Forms part of the polypeptide exit tunnel
CPIN17261_RS00485	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CPIN17261_RS00490	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CPIN17261_RS00500	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CPIN17261_RS00525	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CPIN17261_RS00540	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CPIN17261_RS00545	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CPIN17261_RS00560	COG0200	Binds to the 23S rRNA
CPIN17261_RS00565	COG0201	protein transport
CPIN17261_RS00570	COG0024	Methionine aminopeptidase
CPIN17261_RS00575	COG0840	transmembrane signaling receptor activity
CPIN17261_RS00580	COG3290	protein histidine kinase activity
CPIN17261_RS00580	COG0840	transmembrane signaling receptor activity
CPIN17261_RS00585	COG1749	Flagellar hook protein flgE
CPIN17261_RS00590	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CPIN17261_RS00600	COG0575	Belongs to the CDS family
CPIN17261_RS00625	COG2089	acid synthase
CPIN17261_RS00640	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CPIN17261_RS00655	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CPIN17261_RS00680	COG0460	homoserine dehydrogenase
CPIN17261_RS00685	COG0792	nuclease activity
CPIN17261_RS00690	COG3118	belongs to the thioredoxin family
CPIN17261_RS00700	COG0492	ferredoxin-NADP+ reductase activity
CPIN17261_RS00710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CPIN17261_RS00715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CPIN17261_RS00720	COG1028	Short-chain dehydrogenase reductase Sdr
CPIN17261_RS00730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CPIN17261_RS00750	COG1696	Membrane protein involved in D-alanine export
CPIN17261_RS00755	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CPIN17261_RS00765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CPIN17261_RS00770	COG1049	propionate catabolic process, 2-methylcitrate cycle
CPIN17261_RS00785	COG1757	Na H antiporter
CPIN17261_RS00790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CPIN17261_RS00795	COG1832	CoA-binding protein
CPIN17261_RS00800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CPIN17261_RS00815	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CPIN17261_RS00815	COG0822	iron-sulfur transferase activity
CPIN17261_RS00815	COG2906	2 iron, 2 sulfur cluster binding
CPIN17261_RS00825	COG0840	transmembrane signaling receptor activity
CPIN17261_RS00830	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CPIN17261_RS00835	COG1987	bacterial-type flagellum assembly
CPIN17261_RS00850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CPIN17261_RS00855	COG0642	Histidine kinase
CPIN17261_RS00860	COG0745	RESPONSE REGULATOR receiver
CPIN17261_RS00865	COG0488	(ABC) transporter
CPIN17261_RS00870	COG0488	(ABC) transporter
CPIN17261_RS00875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CPIN17261_RS00895	COG1045	serine acetyltransferase
CPIN17261_RS00940	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CPIN17261_RS00945	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CPIN17261_RS00950	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CPIN17261_RS00955	COG2194	sulfuric ester hydrolase activity
CPIN17261_RS00970	COG0583	DNA-binding transcription factor activity
CPIN17261_RS00975	COG1053	succinate dehydrogenase
CPIN17261_RS00980	COG1053	succinate dehydrogenase
CPIN17261_RS00990	COG3005	denitrification pathway
CPIN17261_RS01005	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CPIN17261_RS01010	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CPIN17261_RS01020	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CPIN17261_RS01030	COG0203	ribosomal protein L17
CPIN17261_RS01035	COG0748	coenzyme F420 binding
CPIN17261_RS01045	COG0739	heme binding
CPIN17261_RS01045	COG1196	nuclear chromosome segregation
CPIN17261_RS01045	COG0741	lytic transglycosylase activity
CPIN17261_RS01050	COG2239	Acts as a magnesium transporter
CPIN17261_RS01065	COG3383	formate dehydrogenase (NAD+) activity
CPIN17261_RS01070	COG3383	formate dehydrogenase (NAD+) activity
CPIN17261_RS01080	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CPIN17261_RS01080	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CPIN17261_RS01100	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CPIN17261_RS01105	COG4615	Cyclic peptide transporter
CPIN17261_RS01140	COG1793	dna ligase
CPIN17261_RS01165	COG1966	Carbon starvation protein
CPIN17261_RS01175	COG0003	Pfam Anion-transporting ATPase
CPIN17261_RS01195	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CPIN17261_RS01200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CPIN17261_RS01205	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPIN17261_RS01210	COG0651	ATP synthesis coupled electron transport
CPIN17261_RS01215	COG0650	Formate hydrogenlyase subunit 4
CPIN17261_RS01220	COG4237	Hydrogenase 4 membrane
CPIN17261_RS01225	COG0651	ATP synthesis coupled electron transport
CPIN17261_RS01230	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CPIN17261_RS01230	COG3261	NADH dehydrogenase
CPIN17261_RS01240	COG3260	NADH ubiquinone oxidoreductase 20
CPIN17261_RS01255	COG2116	formate transmembrane transporter activity
CPIN17261_RS01285	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CPIN17261_RS01290	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CPIN17261_RS01295	COG1074	ATP-dependent DNA helicase activity
CPIN17261_RS01320	COG2010	Cytochrome c
CPIN17261_RS01335	COG3278	Belongs to the heme-copper respiratory oxidase family
CPIN17261_RS01345	COG0505	Belongs to the CarA family
CPIN17261_RS01360	COG0745	RESPONSE REGULATOR receiver
CPIN17261_RS01395	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CPIN17261_RS01415	COG0105	UTP biosynthetic process
CPIN17261_RS01425	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CPIN17261_RS01435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CPIN17261_RS01445	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CPIN17261_RS01450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CPIN17261_RS01470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CPIN17261_RS01475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CPIN17261_RS01490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CPIN17261_RS01495	COG0049	tRNA binding
CPIN17261_RS01500	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CPIN17261_RS01505	COG1309	transcriptional regulator
CPIN17261_RS01515	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CPIN17261_RS01530	COG0754	glutathionylspermidine amidase activity
CPIN17261_RS01535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPIN17261_RS01540	COG1666	GTP binding
CPIN17261_RS01545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CPIN17261_RS01570	COG0437	4 iron, 4 sulfur cluster binding
CPIN17261_RS01575	COG0348	domain, Protein
CPIN17261_RS01580	COG3043	anaerobic respiration
CPIN17261_RS01600	COG0783	Belongs to the Dps family
CPIN17261_RS01620	COG0546	phosphoglycolate phosphatase activity
CPIN17261_RS01635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPIN17261_RS01640	COG0577	efflux transmembrane transporter activity
CPIN17261_RS01640	COG1136	(ABC) transporter
CPIN17261_RS01645	COG4968	Prepilin-type N-terminal cleavage methylation domain
CPIN17261_RS01655	COG2165	general secretion pathway protein
CPIN17261_RS01665	COG2205	protein histidine kinase activity
CPIN17261_RS01670	COG0745	RESPONSE REGULATOR receiver
CPIN17261_RS01675	COG3301	Polysulphide reductase, NrfD
CPIN17261_RS01680	COG0437	4 iron, 4 sulfur cluster binding
CPIN17261_RS01685	COG0243	molybdopterin cofactor binding
CPIN17261_RS01695	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CPIN17261_RS01700	COG0237	dephospho-CoA kinase activity
CPIN17261_RS01705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CPIN17261_RS01715	COG1580	Controls the rotational direction of flagella during chemotaxis
CPIN17261_RS01720	COG0181	hydroxymethylbilane synthase activity
CPIN17261_RS01740	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CPIN17261_RS01745	COG0142	geranyltranstransferase activity
CPIN17261_RS01755	COG0546	phosphoglycolate phosphatase activity
CPIN17261_RS01765	COG1749	Flagellar hook protein flgE
CPIN17261_RS01780	COG1217	gtp-binding protein TYPA
CPIN17261_RS01800	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CPIN17261_RS01805	COG2252	PERMEase
CPIN17261_RS01810	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CPIN17261_RS01820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CPIN17261_RS01840	COG1024	Enoyl-CoA hydratase
CPIN17261_RS01850	COG0657	acetylesterase activity
CPIN17261_RS01860	COG1960	acyl-CoA dehydrogenase activity
CPIN17261_RS01865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CPIN17261_RS01870	COG0318	PFAM AMP-dependent synthetase and ligase
CPIN17261_RS01875	COG0644	oxidoreductase
CPIN17261_RS01880	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CPIN17261_RS01920	COG0280	phosphate acetyltransferase
CPIN17261_RS01920	COG0281	malic enzyme
CPIN17261_RS01950	COG1793	dna ligase
CPIN17261_RS01975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CPIN17261_RS01980	COG0731	radical SAM domain protein
CPIN17261_RS01995	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CPIN17261_RS02005	COG0804	urea catabolic process
CPIN17261_RS02010	COG0832	Belongs to the urease beta subunit family
CPIN17261_RS02010	COG0831	urea catabolic process
CPIN17261_RS02015	COG0831	urea catabolic process
CPIN17261_RS02020	COG0829	nickel cation binding
CPIN17261_RS02030	COG0830	nickel cation binding
CPIN17261_RS02035	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CPIN17261_RS02050	COG1733	regulation of RNA biosynthetic process
CPIN17261_RS02055	COG1979	alcohol dehydrogenase
CPIN17261_RS02065	COG0778	Nitroreductase
CPIN17261_RS02070	COG0716	FMN binding
CPIN17261_RS02120	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPIN17261_RS02120	COG4624	Iron only hydrogenase large subunit, C-terminal domain
CPIN17261_RS02135	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CPIN17261_RS02140	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CPIN17261_RS02150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CPIN17261_RS02160	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CPIN17261_RS02170	COG1120	ATPase activity
CPIN17261_RS02180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CPIN17261_RS02200	COG1136	(ABC) transporter
CPIN17261_RS02205	COG1684	flagellar biosynthetic protein fliR
CPIN17261_RS02215	COG0194	GDP metabolic process
CPIN17261_RS02220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CPIN17261_RS02240	COG0723	plastoquinol--plastocyanin reductase activity
CPIN17261_RS02245	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CPIN17261_RS02290	COG0484	heat shock protein binding
CPIN17261_RS02305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CPIN17261_RS02305	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CPIN17261_RS02310	COG0174	glutamine synthetase
CPIN17261_RS02320	COG0826	peptidase U32
CPIN17261_RS02325	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CPIN17261_RS02340	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CPIN17261_RS02350	COG1519	Transferase
CPIN17261_RS02355	COG0564	pseudouridine synthase activity
CPIN17261_RS02360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CPIN17261_RS02365	COG0228	four-way junction DNA binding
CPIN17261_RS02370	COG1837	Belongs to the UPF0109 family
CPIN17261_RS02385	COG0335	large ribosomal subunit rRNA binding
CPIN17261_RS02390	COG4773	Receptor
CPIN17261_RS02415	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CPIN17261_RS02445	COG1793	dna ligase
CPIN17261_RS02455	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CPIN17261_RS02460	COG4106	trans-aconitate 2-methyltransferase activity
CPIN17261_RS02485	COG4786	Flagellar basal body rod
CPIN17261_RS02490	COG4786	Flagellar basal body rod
CPIN17261_RS02495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CPIN17261_RS02510	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CPIN17261_RS02530	COG0248	Ppx GppA phosphatase
CPIN17261_RS02540	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CPIN17261_RS02555	COG1181	Belongs to the D-alanine--D-alanine ligase family
CPIN17261_RS02570	COG0728	peptidoglycan biosynthetic process
CPIN17261_RS02580	COG1132	(ABC) transporter
CPIN17261_RS02585	COG0167	dihydroorotate dehydrogenase activity
CPIN17261_RS02595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CPIN17261_RS02600	COG1028	Short-chain dehydrogenase reductase Sdr
CPIN17261_RS02620	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CPIN17261_RS02640	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CPIN17261_RS02645	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CPIN17261_RS02650	COG1663	tetraacyldisaccharide 4'-kinase activity
CPIN17261_RS02655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CPIN17261_RS02730	COG3041	Addiction module toxin RelE StbE family
CPIN17261_RS02745	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CPIN17261_RS02760	COG0210	DNA helicase
CPIN17261_RS02770	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CPIN17261_RS02775	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CPIN17261_RS02790	COG1815	bacterial-type flagellum-dependent cell motility
CPIN17261_RS02795	COG1558	bacterial-type flagellum-dependent cell motility
CPIN17261_RS02800	COG1677	Flagellar hook-basal body complex protein FliE
CPIN17261_RS02805	COG0768	penicillin binding
CPIN17261_RS02835	COG0519	Catalyzes the synthesis of GMP from XMP
CPIN17261_RS02835	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CPIN17261_RS02910	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CPIN17261_RS02925	COG0517	IMP dehydrogenase activity
CPIN17261_RS02925	COG1125	glycine betaine transport
CPIN17261_RS02930	COG1174	glycine betaine transport
CPIN17261_RS02935	COG0799	negative regulation of ribosome biogenesis
CPIN17261_RS02945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CPIN17261_RS02950	COG0126	phosphoglycerate kinase activity
CPIN17261_RS02955	COG0149	triose-phosphate isomerase activity
CPIN17261_RS02960	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CPIN17261_RS02965	COG0733	neurotransmitter:sodium symporter activity
CPIN17261_RS02970	COG0534	Mate efflux family protein
CPIN17261_RS02980	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CPIN17261_RS02985	COG0552	protein localization to endoplasmic reticulum
CPIN17261_RS02990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CPIN17261_RS03000	COG1418	mRNA catabolic process
CPIN17261_RS03025	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPIN17261_RS03035	COG0138	bifunctional purine biosynthesis protein purh
CPIN17261_RS03045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CPIN17261_RS03050	COG0612	Peptidase, M16
CPIN17261_RS03055	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CPIN17261_RS03095	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CPIN17261_RS03105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CPIN17261_RS03110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CPIN17261_RS03115	COG0521	Mo-molybdopterin cofactor biosynthetic process
CPIN17261_RS03125	COG0443	Heat shock 70 kDa protein
CPIN17261_RS03130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CPIN17261_RS03135	COG1420	regulation of RNA biosynthetic process
CPIN17261_RS03150	COG0772	Belongs to the SEDS family
CPIN17261_RS03170	COG1166	arginine decarboxylase activity
CPIN17261_RS03175	COG0124	histidyl-tRNA synthetase
CPIN17261_RS03180	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CPIN17261_RS03185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CPIN17261_RS03190	COG0163	prenyltransferase activity
CPIN17261_RS03210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CPIN17261_RS03215	COG2833	Protein of unknown function (DUF455)
CPIN17261_RS03235	COG0706	membrane insertase activity
CPIN17261_RS03245	COG0594	ribonuclease P activity
CPIN17261_RS03250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CPIN17261_RS03265	COG0824	Thioesterase
CPIN17261_RS03290	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CPIN17261_RS03295	COG0788	formyltetrahydrofolate deformylase activity
CPIN17261_RS03300	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CPIN17261_RS03305	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CPIN17261_RS03310	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CPIN17261_RS03340	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CPIN17261_RS03340	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CPIN17261_RS03345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPIN17261_RS03350	COG0765	amino acid transport
CPIN17261_RS03370	COG0352	thiamine-phosphate diphosphorylase activity
CPIN17261_RS03380	COG0537	adenosine 5'-monophosphoramidase activity
CPIN17261_RS03385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CPIN17261_RS03395	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CPIN17261_RS03405	COG0539	negative regulation of cytoplasmic translation
CPIN17261_RS03405	COG1185	polyribonucleotide nucleotidyltransferase activity
CPIN17261_RS03415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CPIN17261_RS03430	COG0305	Participates in initiation and elongation during chromosome replication
CPIN17261_RS03440	COG1295	ribonuclease BN
CPIN17261_RS03445	COG0582	viral genome integration into host DNA
CPIN17261_RS03470	COG0642	Histidine kinase
CPIN17261_RS03475	COG0165	Argininosuccinate lyase
CPIN17261_RS03485	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CPIN17261_RS03495	COG0039	L-malate dehydrogenase activity
CPIN17261_RS03505	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CPIN17261_RS03515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPIN17261_RS03520	COG2011	ABC-type metal ion transport system permease component
CPIN17261_RS03525	COG1464	Belongs to the NlpA lipoprotein family
CPIN17261_RS03530	COG1280	lysine exporter protein (LysE YggA)
CPIN17261_RS03540	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CPIN17261_RS03540	COG2050	protein possibly involved in aromatic compounds catabolism
CPIN17261_RS03550	COG1305	Transglutaminase-like
CPIN17261_RS03565	COG2195	Cleaves the N-terminal amino acid of tripeptides
CPIN17261_RS03570	COG0542	response to heat
CPIN17261_RS03575	COG0793	Belongs to the peptidase S41A family
CPIN17261_RS03580	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CPIN17261_RS03585	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPIN17261_RS03590	COG0047	phosphoribosylformylglycinamidine synthase activity
CPIN17261_RS03600	COG0204	Acyl-transferase
CPIN17261_RS03605	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CPIN17261_RS03615	COG2217	Heavy metal translocating P-type atpase
CPIN17261_RS03630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CPIN17261_RS03635	COG3022	response to hydroperoxide
CPIN17261_RS03640	COG0776	regulation of translation
CPIN17261_RS03655	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CPIN17261_RS03660	COG2204	response regulator
CPIN17261_RS03690	COG0280	phosphate acetyltransferase
CPIN17261_RS03700	COG0484	heat shock protein binding
CPIN17261_RS03705	COG0789	Transcriptional regulator
CPIN17261_RS03715	COG0587	DNA-directed DNA polymerase activity
CPIN17261_RS03720	COG0724	RNA recognition motif
CPIN17261_RS03725	COG0693	protein deglycase activity
CPIN17261_RS03735	COG0252	asparaginase activity
CPIN17261_RS03750	COG4574	serine-type endopeptidase inhibitor activity
CPIN17261_RS03755	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CPIN17261_RS03760	COG2244	polysaccharide biosynthetic process
CPIN17261_RS03770	COG0438	transferase activity, transferring glycosyl groups
CPIN17261_RS03775	COG1215	transferase activity, transferring glycosyl groups
CPIN17261_RS03780	COG0438	transferase activity, transferring glycosyl groups
CPIN17261_RS03790	COG0438	transferase activity, transferring glycosyl groups
CPIN17261_RS03795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CPIN17261_RS03820	COG0733	neurotransmitter:sodium symporter activity
CPIN17261_RS03840	COG0473	3-isopropylmalate dehydrogenase activity
CPIN17261_RS03845	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CPIN17261_RS03855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CPIN17261_RS03860	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CPIN17261_RS03880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CPIN17261_RS03885	COG1301	dicarboxylic acid transport
CPIN17261_RS03890	COG0778	Nitroreductase
CPIN17261_RS03895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CPIN17261_RS03905	COG3340	Belongs to the peptidase S51 family
CPIN17261_RS03910	COG3069	C4-dicarboxylate transmembrane transporter activity
CPIN17261_RS03915	COG2195	Cleaves the N-terminal amino acid of tripeptides
CPIN17261_RS03920	COG2271	Major facilitator Superfamily
CPIN17261_RS03925	COG0733	neurotransmitter:sodium symporter activity
CPIN17261_RS03935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CPIN17261_RS03945	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CPIN17261_RS03950	COG1472	Belongs to the glycosyl hydrolase 3 family
CPIN17261_RS03955	COG1252	NADH dehydrogenase
CPIN17261_RS03975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CPIN17261_RS04020	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CPIN17261_RS04035	COG0137	argininosuccinate synthase activity
CPIN17261_RS04055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CPIN17261_RS04065	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CPIN17261_RS04070	COG0802	atpase or kinase
CPIN17261_RS04075	COG1137	ATPase activity
CPIN17261_RS04080	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CPIN17261_RS04090	COG0326	Molecular chaperone. Has ATPase activity
CPIN17261_RS04110	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CPIN17261_RS04115	COG0298	carbon dioxide binding
CPIN17261_RS04120	COG0409	Hydrogenase expression formation protein
CPIN17261_RS04125	COG0309	Hydrogenase expression formation protein (HypE)
CPIN17261_RS04130	COG0375	protein maturation
CPIN17261_RS04140	COG1304	FMN binding
CPIN17261_RS04150	COG0415	Belongs to the DNA photolyase family
CPIN17261_RS04160	COG0440	acetolactate synthase activity
CPIN17261_RS04165	COG0028	Belongs to the TPP enzyme family
CPIN17261_RS04175	COG1196	nuclear chromosome segregation
CPIN17261_RS04175	COG1674	ftsk spoiiie
CPIN17261_RS04205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CPIN17261_RS04225	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CPIN17261_RS04230	COG0628	permease
CPIN17261_RS04250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CPIN17261_RS04255	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CPIN17261_RS04265	COG1496	oxidoreductase activity
CPIN17261_RS04280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CPIN17261_RS04285	COG0268	Binds directly to 16S ribosomal RNA
CPIN17261_RS04295	COG0582	viral genome integration into host DNA
CPIN17261_RS04335	COG0629	single-stranded DNA binding
CPIN17261_RS04425	COG3657	addiction module killer protein
CPIN17261_RS04430	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CPIN17261_RS04625	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CPIN17261_RS04640	COG0765	amino acid transport
CPIN17261_RS04645	COG0765	amino acid transport
CPIN17261_RS04650	COG1126	abc transporter atp-binding protein
CPIN17261_RS04655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CPIN17261_RS04660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CPIN17261_RS04665	COG0849	cell division
CPIN17261_RS04680	COG0275	rRNA processing
CPIN17261_RS04690	COG2046	Belongs to the sulfate adenylyltransferase family
CPIN17261_RS04695	COG0745	RESPONSE REGULATOR receiver
CPIN17261_RS04705	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CPIN17261_RS04710	COG0489	protein tyrosine kinase activity
CPIN17261_RS04770	COG0314	molybdopterin synthase activity
CPIN17261_RS04775	COG0303	'Molybdopterin
CPIN17261_RS04785	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CPIN17261_RS04795	COG0688	phosphatidylethanolamine metabolic process
CPIN17261_RS04800	COG1408	metallophosphoesterase
CPIN17261_RS04810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CPIN17261_RS04815	COG1116	anion transmembrane transporter activity
CPIN17261_RS04820	COG4771	TonB-dependent receptor
CPIN17261_RS04820	COG1629	transport
CPIN17261_RS04830	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CPIN17261_RS04835	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CPIN17261_RS04850	COG0733	neurotransmitter:sodium symporter activity
CPIN17261_RS04855	COG0733	neurotransmitter:sodium symporter activity
CPIN17261_RS04860	COG0733	neurotransmitter:sodium symporter activity
CPIN17261_RS04865	COG1304	FMN binding
CPIN17261_RS05145	COG0629	single-stranded DNA binding
CPIN17261_RS05200	COG0582	viral genome integration into host DNA
CPIN17261_RS05215	COG1556	Lactate utilization protein
CPIN17261_RS05220	COG1139	Iron-sulfur cluster binding protein
CPIN17261_RS05225	COG0247	lactate metabolic process
CPIN17261_RS05230	COG1620	l-lactate permease
CPIN17261_RS05240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CPIN17261_RS05255	COG1338	Plays a role in the flagellum-specific transport system
CPIN17261_RS05260	COG1360	Flagellar Motor Protein
CPIN17261_RS05265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CPIN17261_RS05275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CPIN17261_RS05285	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CPIN17261_RS05290	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CPIN17261_RS05300	COG0101	tRNA pseudouridine synthase activity
CPIN17261_RS05305	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CPIN17261_RS05320	COG4771	TonB-dependent receptor
CPIN17261_RS05320	COG1629	transport
CPIN17261_RS05325	COG0745	RESPONSE REGULATOR receiver
CPIN17261_RS05345	COG3976	FMN-binding domain protein
CPIN17261_RS05345	COG1053	succinate dehydrogenase
CPIN17261_RS05355	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CPIN17261_RS05365	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CPIN17261_RS05370	COG2404	hydrolase activity, acting on ester bonds
CPIN17261_RS05410	COG2022	thiamine diphosphate biosynthetic process
CPIN17261_RS05415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CPIN17261_RS05425	COG2171	N-acyltransferase activity
CPIN17261_RS05445	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CPIN17261_RS05475	COG1706	bacterial-type flagellum-dependent cell motility
CPIN17261_RS05480	COG3951	Flagellar rod assembly protein muramidase FlgJ
CPIN17261_RS05510	COG1741	Belongs to the pirin family
CPIN17261_RS05545	COG0437	4 iron, 4 sulfur cluster binding
CPIN17261_RS05555	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CPIN17261_RS05570	COG0343	queuine tRNA-ribosyltransferase activity
CPIN17261_RS05575	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CPIN17261_RS05580	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CPIN17261_RS05585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CPIN17261_RS05595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CPIN17261_RS05615	COG0602	queuosine metabolic process
CPIN17261_RS05645	COG0191	fructose-bisphosphate aldolase activity
CPIN17261_RS05650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CPIN17261_RS05655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CPIN17261_RS05665	COG0484	heat shock protein binding
CPIN17261_RS05670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CPIN17261_RS05675	COG0745	RESPONSE REGULATOR receiver
CPIN17261_RS05680	COG0642	Histidine kinase
CPIN17261_RS05690	COG0556	nucleotide-excision repair
CPIN17261_RS05710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CPIN17261_RS05715	COG2201	protein-glutamate methylesterase activity
CPIN17261_RS05720	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CPIN17261_RS05730	COG1333	cytochrome c biogenesis protein
CPIN17261_RS05730	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CPIN17261_RS05755	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CPIN17261_RS05770	COG0527	aspartate kinase activity
CPIN17261_RS05775	COG0494	nUDIX hydrolase
CPIN17261_RS05780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CPIN17261_RS05785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CPIN17261_RS05790	COG0805	protein transport
CPIN17261_RS05795	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CPIN17261_RS05805	COG1027	Aspartate ammonia-lyase
CPIN17261_RS05810	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CPIN17261_RS05820	COG0616	signal peptide processing
CPIN17261_RS05825	COG0402	S-adenosylhomocysteine deaminase activity
CPIN17261_RS05830	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CPIN17261_RS05835	COG0006	proline dipeptidase activity
CPIN17261_RS05840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CPIN17261_RS05845	COG1419	protein localization to endoplasmic reticulum
CPIN17261_RS05850	COG0455	bacterial-type flagellum organization
CPIN17261_RS05865	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CPIN17261_RS05870	COG1776	CheC inhibitor of MCP methylation
CPIN17261_RS05870	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CPIN17261_RS05875	COG1611	Belongs to the LOG family
CPIN17261_RS05880	COG0482	sulfurtransferase activity
CPIN17261_RS05885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPIN17261_RS05900	COG0811	peptide transport
CPIN17261_RS05905	COG0848	biopolymer transport protein
CPIN17261_RS05915	COG2151	metal-sulfur cluster biosynthetic enzyme
CPIN17261_RS05945	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CPIN17261_RS05965	COG0727	PFAM Uncharacterised protein family (UPF0153)
CPIN17261_RS05970	COG2813	Specifically methylates the guanine in position
CPIN17261_RS05980	COG0492	ferredoxin-NADP+ reductase activity
CPIN17261_RS05985	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CPIN17261_RS05990	COG2962	Rard protein
CPIN17261_RS06000	COG0750	zinc metalloprotease
CPIN17261_RS06005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CPIN17261_RS06015	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CPIN17261_RS06040	COG2121	Domain of unknown function (DUF374)
CPIN17261_RS06055	COG0195	Participates in both transcription termination and antitermination
CPIN17261_RS06065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CPIN17261_RS06080	COG0708	Exodeoxyribonuclease III
CPIN17261_RS06095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CPIN17261_RS06115	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CPIN17261_RS06120	COG1218	3'(2'),5'-bisphosphate nucleotidase
CPIN17261_RS06125	COG0372	Belongs to the citrate synthase family
CPIN17261_RS06130	COG0475	glutathione-regulated potassium exporter activity
CPIN17261_RS06130	COG0569	domain protein
CPIN17261_RS06135	COG0037	tRNA processing
CPIN17261_RS06140	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CPIN17261_RS06150	COG1047	Peptidyl-prolyl cis-trans
CPIN17261_RS06160	COG2885	chlorophyll binding
CPIN17261_RS06175	COG0848	biopolymer transport protein
CPIN17261_RS06180	COG0811	peptide transport
CPIN17261_RS06195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CPIN17261_RS06200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CPIN17261_RS06220	COG1475	DNA binding
CPIN17261_RS06225	COG1192	Involved in chromosome partitioning
CPIN17261_RS06230	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CPIN17261_RS06230	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CPIN17261_RS06255	COG1228	amidohydrolase
CPIN17261_RS06265	COG1335	isochorismatase
CPIN17261_RS06270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CPIN17261_RS06275	COG1183	phosphatidylcholine synthase activity
CPIN17261_RS06280	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CPIN17261_RS06285	COG2264	protein methyltransferase activity
CPIN17261_RS06290	COG0745	RESPONSE REGULATOR receiver
CPIN17261_RS06300	COG1086	Polysaccharide biosynthesis protein
CPIN17261_RS06305	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CPIN17261_RS06350	COG0330	HflC and HflK could
CPIN17261_RS06370	COG1970	mechanosensitive ion channel activity
CPIN17261_RS06400	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CPIN17261_RS06410	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPIN17261_RS06410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPIN17261_RS06440	COG5001	Diguanylate cyclase
CPIN17261_RS06440	COG3300	MHYT domain
CPIN17261_RS06450	COG5001	Diguanylate cyclase
CPIN17261_RS06450	COG3706	GGDEF domain
CPIN17261_RS06450	COG4251	negative regulation of phosphorylation
CPIN17261_RS06450	COG2203	Gaf domain
CPIN17261_RS06460	COG0497	DNA recombination
CPIN17261_RS06470	COG0084	hydrolase, TatD family'
CPIN17261_RS06480	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CPIN17261_RS06515	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CPIN17261_RS06520	COG0840	transmembrane signaling receptor activity
CPIN17261_RS06525	COG0166	Belongs to the GPI family
CPIN17261_RS06540	COG4662	Binding-protein-dependent transport system inner membrane component
CPIN17261_RS06545	COG2998	abc-type tungstate transport system, permease component
CPIN17261_RS06550	COG1739	Uncharacterized protein family UPF0029
CPIN17261_RS06695	COG4695	Portal protein
CPIN17261_RS06765	COG2842	Transposition protein
CPIN17261_RS06795	COG1053	succinate dehydrogenase
CPIN17261_RS06800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CPIN17261_RS06810	COG2257	FlhB HrpN YscU SpaS Family
CPIN17261_RS06850	COG0681	Belongs to the peptidase S26 family
CPIN17261_RS06855	COG1994	Peptidase M50
CPIN17261_RS06860	COG0698	ribose 5-phosphate isomerase
CPIN17261_RS06875	COG0586	Pfam SNARE associated Golgi protein
CPIN17261_RS06880	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CPIN17261_RS06885	COG0012	GTP binding
CPIN17261_RS06900	COG1127	ABC transporter
CPIN17261_RS06905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CPIN17261_RS06910	COG0439	Biotin carboxylase
CPIN17261_RS06920	COG1921	L-seryl-tRNASec selenium transferase activity
CPIN17261_RS06950	COG0083	homoserine kinase activity
CPIN17261_RS06975	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CPIN17261_RS06980	COG2217	Heavy metal translocating P-type atpase
CPIN17261_RS07050	COG2860	membrane
CPIN17261_RS07055	COG0450	alkyl hydroperoxide reductase
CPIN17261_RS07075	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CPIN17261_RS07075	COG1776	CheC inhibitor of MCP methylation
CPIN17261_RS07100	COG0859	PFAM glycosyl transferase family 9
CPIN17261_RS07110	COG0463	Glycosyl transferase, family 2
CPIN17261_RS07115	COG0859	PFAM glycosyl transferase family 9
CPIN17261_RS07120	COG0726	polysaccharide deacetylase
CPIN17261_RS07130	COG0438	transferase activity, transferring glycosyl groups
CPIN17261_RS07135	COG0859	PFAM glycosyl transferase family 9
CPIN17261_RS07145	COG0438	transferase activity, transferring glycosyl groups
CPIN17261_RS07170	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CPIN17261_RS07175	COG0085	RNA polymerase activity
CPIN17261_RS07180	COG0222	ribosome binding
CPIN17261_RS07185	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CPIN17261_RS07195	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CPIN17261_RS07200	COG0250	Participates in transcription elongation, termination and antitermination
CPIN17261_RS07215	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CPIN17261_RS07220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CPIN17261_RS07255	COG2197	response regulator
CPIN17261_RS07265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPIN17261_RS07290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CPIN17261_RS07300	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CPIN17261_RS07305	COG0113	porphobilinogen synthase activity
CPIN17261_RS07310	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CPIN17261_RS07315	COG0357	Ribosomal RNA small subunit methyltransferase G
CPIN17261_RS07330	COG0501	Belongs to the peptidase M48B family
CPIN17261_RS07335	COG0579	oxidoreductase
CPIN17261_RS07340	COG0783	Belongs to the Dps family
CPIN17261_RS07345	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CPIN17261_RS07350	COG2824	Alkylphosphonate utilization operon protein PhnA
CPIN17261_RS07355	COG0772	Belongs to the SEDS family
CPIN17261_RS07360	COG0564	pseudouridine synthase activity
CPIN17261_RS07370	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CPIN17261_RS07375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPIN17261_RS07395	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CPIN17261_RS07400	COG0528	UMP kinase activity
CPIN17261_RS07410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CPIN17261_RS07415	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CPIN17261_RS07430	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CPIN17261_RS07430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CPIN17261_RS07455	COG0445	tRNA wobble uridine modification
CPIN17261_RS07470	COG1755	Isoprenylcysteine carboxyl methyltransferase
CPIN17261_RS07480	COG2056	Na+-H+ antiporter family
CPIN17261_RS07515	COG1823	symporter activity
CPIN17261_RS07520	COG0628	permease
CPIN17261_RS07525	COG2255	four-way junction helicase activity
CPIN17261_RS07540	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CPIN17261_RS07570	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CPIN17261_RS07590	COG2831	hemolysin activation secretion protein
CPIN17261_RS07620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CPIN17261_RS07635	COG2861	carbohydrate metabolic process
CPIN17261_RS07650	COG0557	exoribonuclease II activity
CPIN17261_RS07660	COG0360	Binds together with S18 to 16S ribosomal RNA
CPIN17261_RS07665	COG0629	single-stranded DNA binding
CPIN17261_RS07685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CPIN17261_RS07705	COG0500	methyltransferase
CPIN17261_RS07720	COG1570	exodeoxyribonuclease VII activity
CPIN17261_RS07740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CPIN17261_RS07750	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CPIN17261_RS07755	COG1766	The M ring may be actively involved in energy transduction
CPIN17261_RS07760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CPIN17261_RS07765	COG0077	Prephenate dehydratase
CPIN17261_RS07765	COG1605	Chorismate mutase
CPIN17261_RS07770	COG0019	diaminopimelate decarboxylase activity
CPIN17261_RS07785	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CPIN17261_RS07795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CPIN17261_RS07800	COG0560	Phosphoserine phosphatase
CPIN17261_RS07805	COG0835	chemotaxis
CPIN17261_RS07810	COG0784	Response regulator, receiver
CPIN17261_RS07810	COG0643	Histidine kinase
CPIN17261_RS07810	COG2198	Histidine kinase
CPIN17261_RS07815	COG0784	Response regulator, receiver
CPIN17261_RS07815	COG0835	chemotaxis
CPIN17261_RS07825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CPIN17261_RS07835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CPIN17261_RS07845	COG1115	amino acid carrier protein
CPIN17261_RS07850	COG0814	amino acid
CPIN17261_RS07855	COG1760	l-serine dehydratase
CPIN17261_RS07865	COG0243	molybdopterin cofactor binding
CPIN17261_RS07870	COG3383	formate dehydrogenase (NAD+) activity
CPIN17261_RS07875	COG0437	4 iron, 4 sulfur cluster binding
CPIN17261_RS07890	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CPIN17261_RS07895	COG2814	Major facilitator Superfamily
CPIN17261_RS07900	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPIN17261_RS07900	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CPIN17261_RS07900	COG1013	pyruvate-flavodoxin oxidoreductase activity
CPIN17261_RS07900	COG0674	pyruvate-flavodoxin oxidoreductase activity
CPIN17261_RS07920	COG0778	Nitroreductase
CPIN17261_RS07925	COG2249	NAD(P)H dehydrogenase (quinone) activity
CPIN17261_RS07945	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CPIN17261_RS07950	COG1115	amino acid carrier protein
CPIN17261_RS07955	COG1294	oxidase, subunit
CPIN17261_RS07960	COG1271	oxidase subunit
CPIN17261_RS07970	COG0504	CTP synthase activity
CPIN17261_RS07990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CPIN17261_RS08005	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CPIN17261_RS08010	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CPIN17261_RS08015	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CPIN17261_RS08020	COG4968	Prepilin-type N-terminal cleavage methylation domain
CPIN17261_RS08045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CPIN17261_RS08050	COG1942	4-Oxalocrotonate Tautomerase
CPIN17261_RS08080	COG1979	alcohol dehydrogenase
CPIN17261_RS08095	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CPIN17261_RS08105	COG1696	Membrane protein involved in D-alanine export
CPIN17261_RS08110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CPIN17261_RS08120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CPIN17261_RS08125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CPIN17261_RS08145	COG4750	Nucleotidyl transferase
CPIN17261_RS08150	COG3475	LICD family
CPIN17261_RS08155	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CPIN17261_RS08155	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CPIN17261_RS08165	COG0243	molybdopterin cofactor binding
CPIN17261_RS08180	COG0243	molybdopterin cofactor binding
CPIN17261_RS08220	COG0716	FMN binding
CPIN17261_RS08225	COG0352	thiamine-phosphate diphosphorylase activity
CPIN17261_RS08230	COG0670	Belongs to the BI1 family
CPIN17261_RS08235	COG0288	reversible hydration of carbon dioxide
CPIN17261_RS08240	COG0668	transmembrane transport
CPIN17261_RS08245	COG3706	GGDEF domain
CPIN17261_RS08250	COG3706	GGDEF domain
CPIN17261_RS08255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CPIN17261_RS08280	COG0318	PFAM AMP-dependent synthetase and ligase
CPIN17261_RS08285	COG1222	aaa ATPase
CPIN17261_RS08290	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CPIN17261_RS08295	COG0233	cytoplasmic translational termination
CPIN17261_RS08300	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CPIN17261_RS08310	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CPIN17261_RS08315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CPIN17261_RS08330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CPIN17261_RS08355	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CPIN17261_RS08375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CPIN17261_RS08405	COG5001	Diguanylate cyclase
CPIN17261_RS08405	COG3300	MHYT domain
CPIN17261_RS08410	COG1193	negative regulation of DNA recombination
CPIN17261_RS08430	COG0519	Catalyzes the synthesis of GMP from XMP
CPIN17261_RS08450	COG2226	methyltransferase
CPIN17261_RS08455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CPIN17261_RS08485	COG2423	ornithine cyclodeaminase activity
CPIN17261_RS08495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CPIN17261_RS08515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CPIN17261_RS08520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CPIN17261_RS08525	COG4310	Domain of unknown function (DUF2172)
CPIN17261_RS08530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CPIN17261_RS08530	COG4797	methyltransferase
CPIN17261_RS08565	COG1981	membrane
CPIN17261_RS08590	COG3287	FIST C domain
CPIN17261_RS08590	COG2200	EAL domain
CPIN17261_RS08590	COG2199	diguanylate cyclase activity
CPIN17261_RS08595	COG1858	cytochrome C peroxidase
CPIN17261_RS08600	COG2264	protein methyltransferase activity
CPIN17261_RS08610	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CPIN17261_RS08650	COG1722	exodeoxyribonuclease VII activity
CPIN17261_RS08655	COG0517	IMP dehydrogenase activity
CPIN17261_RS08655	COG0516	GMP reductase activity
CPIN17261_RS08660	COG0154	amidase activity
CPIN17261_RS08670	COG1546	Belongs to the CinA family
CPIN17261_RS08670	COG1058	Belongs to the CinA family
CPIN17261_RS08690	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CPIN17261_RS08700	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CPIN17261_RS08705	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CPIN17261_RS08710	COG1862	Preprotein translocase
CPIN17261_RS08715	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPIN17261_RS08720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPIN17261_RS08750	COG0840	transmembrane signaling receptor activity
CPIN17261_RS08755	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CPIN17261_RS08765	COG1253	flavin adenine dinucleotide binding
CPIN17261_RS08770	COG0251	oxidation-reduction process
CPIN17261_RS08775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPIN17261_RS08795	COG0137	argininosuccinate synthase activity
CPIN17261_RS08800	COG0358	DNA primase activity
CPIN17261_RS08820	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system