locus-tag	class	description
FBF06_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FBF06_RS00010	COG0592	DNA-directed DNA polymerase activity
FBF06_RS00015	COG0187	DNA topoisomerase II activity
FBF06_RS00030	COG2056	Na+-H+ antiporter family
FBF06_RS00035	COG0067	glutamate synthase
FBF06_RS00035	COG0069	glutamate synthase activity
FBF06_RS00035	COG0070	glutamate synthase
FBF06_RS00040	COG0493	'glutamate synthase
FBF06_RS00045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FBF06_RS00055	COG1592	Rubrerythrin
FBF06_RS00075	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FBF06_RS00090	COG0840	transmembrane signaling receptor activity
FBF06_RS00095	COG1858	cytochrome C peroxidase
FBF06_RS00100	COG0179	Fumarylacetoacetate (FAA) hydrolase
FBF06_RS00105	COG0564	pseudouridine synthase activity
FBF06_RS00110	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FBF06_RS00115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FBF06_RS00130	COG0504	CTP synthase activity
FBF06_RS00140	COG0252	asparaginase activity
FBF06_RS00195	COG2814	Major facilitator Superfamily
FBF06_RS00230	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FBF06_RS00260	COG0471	metal ion transport
FBF06_RS00270	COG0471	metal ion transport
FBF06_RS00275	COG0471	metal ion transport
FBF06_RS00280	COG0482	sulfurtransferase activity
FBF06_RS00315	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FBF06_RS00315	COG1776	CheC inhibitor of MCP methylation
FBF06_RS00320	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FBF06_RS00325	COG1191	sigma factor activity
FBF06_RS00335	COG0455	bacterial-type flagellum organization
FBF06_RS00340	COG1419	protein localization to endoplasmic reticulum
FBF06_RS00345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FBF06_RS00350	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FBF06_RS00355	COG0402	S-adenosylhomocysteine deaminase activity
FBF06_RS00360	COG0616	signal peptide processing
FBF06_RS00385	COG1139	Iron-sulfur cluster binding protein
FBF06_RS00390	COG0247	lactate metabolic process
FBF06_RS00405	COG3021	interspecies interaction between organisms
FBF06_RS00420	COG1271	oxidase subunit
FBF06_RS00425	COG1294	oxidase, subunit
FBF06_RS00430	COG1794	racemase activity, acting on amino acids and derivatives
FBF06_RS00440	COG1027	Aspartate ammonia-lyase
FBF06_RS00445	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FBF06_RS00475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FBF06_RS00480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FBF06_RS00500	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FBF06_RS00500	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FBF06_RS00505	COG1192	Involved in chromosome partitioning
FBF06_RS00510	COG1475	DNA binding
FBF06_RS00525	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FBF06_RS00540	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FBF06_RS00545	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FBF06_RS00550	COG0811	peptide transport
FBF06_RS00555	COG0848	biopolymer transport protein
FBF06_RS00565	COG0823	Involved in the tonB-independent uptake of proteins
FBF06_RS00570	COG2885	chlorophyll binding
FBF06_RS00580	COG1047	Peptidyl-prolyl cis-trans
FBF06_RS00585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FBF06_RS00590	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FBF06_RS00595	COG0037	tRNA processing
FBF06_RS00620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FBF06_RS00630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FBF06_RS00640	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FBF06_RS00650	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FBF06_RS00675	COG0083	homoserine kinase activity
FBF06_RS00695	COG0779	Required for maturation of 30S ribosomal subunits
FBF06_RS00700	COG1401	restriction endodeoxyribonuclease activity
FBF06_RS00710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FBF06_RS00715	COG1121	(ABC) transporter
FBF06_RS00725	COG0840	transmembrane signaling receptor activity
FBF06_RS00735	COG0492	ferredoxin-NADP+ reductase activity
FBF06_RS00740	COG3118	belongs to the thioredoxin family
FBF06_RS00745	COG0792	nuclease activity
FBF06_RS00750	COG0460	homoserine dehydrogenase
FBF06_RS00755	COG0436	Aminotransferase
FBF06_RS00770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FBF06_RS00775	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FBF06_RS00780	COG0254	rRNA binding
FBF06_RS00785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FBF06_RS00805	COG0602	queuosine metabolic process
FBF06_RS00810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FBF06_RS00835	COG1971	Probably functions as a manganese efflux pump
FBF06_RS00850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FBF06_RS00870	COG1840	ABC-type Fe3 transport system, periplasmic component
FBF06_RS00890	COG0811	peptide transport
FBF06_RS00895	COG0848	biopolymer transport protein
FBF06_RS00905	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FBF06_RS00910	COG1253	flavin adenine dinucleotide binding
FBF06_RS00920	COG2824	Alkylphosphonate utilization operon protein PhnA
FBF06_RS00925	COG0861	Integral membrane protein TerC family
FBF06_RS00930	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FBF06_RS00935	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FBF06_RS00935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FBF06_RS00945	COG0606	chelatase, subunit chli
FBF06_RS00950	COG0242	peptide deformylase activity
FBF06_RS00960	COG0544	peptidyl-prolyl cis-trans isomerase activity
FBF06_RS00970	COG1157	protein secretion by the type III secretion system
FBF06_RS00975	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FBF06_RS00980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FBF06_RS00985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FBF06_RS00985	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FBF06_RS01010	COG2851	Citrate transporter
FBF06_RS01015	COG1297	OPT oligopeptide transporter protein
FBF06_RS01020	COG1968	undecaprenyl-diphosphatase activity
FBF06_RS01030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FBF06_RS01080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FBF06_RS01085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FBF06_RS01090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FBF06_RS01105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FBF06_RS01125	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FBF06_RS01130	COG0670	Belongs to the BI1 family
FBF06_RS01135	COG0288	reversible hydration of carbon dioxide
FBF06_RS01140	COG0668	transmembrane transport
FBF06_RS01165	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FBF06_RS01170	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FBF06_RS01195	COG0477	Major facilitator Superfamily
FBF06_RS01205	COG0315	cyclic pyranopterin monophosphate synthase activity
FBF06_RS01210	COG2921	Belongs to the UPF0250 family
FBF06_RS01220	COG0708	Exodeoxyribonuclease III
FBF06_RS01225	COG2194	sulfuric ester hydrolase activity
FBF06_RS01230	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FBF06_RS01240	COG0418	dihydroorotase activity
FBF06_RS01250	COG2226	methyltransferase
FBF06_RS01255	COG0840	transmembrane signaling receptor activity
FBF06_RS01260	COG0428	transporter
FBF06_RS01280	COG0330	HflC and HflK could
FBF06_RS01290	COG1942	4-Oxalocrotonate Tautomerase
FBF06_RS01295	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FBF06_RS01300	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FBF06_RS01305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FBF06_RS01315	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FBF06_RS01320	COG1077	Cell shape determining protein MreB Mrl
FBF06_RS01330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FBF06_RS01350	COG0835	chemotaxis
FBF06_RS01355	COG2198	Histidine kinase
FBF06_RS01355	COG0784	Response regulator, receiver
FBF06_RS01355	COG0643	Histidine kinase
FBF06_RS01360	COG0784	Response regulator, receiver
FBF06_RS01360	COG0835	chemotaxis
FBF06_RS01370	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FBF06_RS01390	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FBF06_RS01420	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FBF06_RS01435	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FBF06_RS01470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FBF06_RS01475	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FBF06_RS01480	COG2076	Multidrug Resistance protein
FBF06_RS01505	COG0019	diaminopimelate decarboxylase activity
FBF06_RS01520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FBF06_RS01530	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FBF06_RS01555	COG2226	methyltransferase
FBF06_RS01560	COG1570	exodeoxyribonuclease VII activity
FBF06_RS01565	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FBF06_RS01570	COG0251	oxidation-reduction process
FBF06_RS01585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FBF06_RS01605	COG0450	alkyl hydroperoxide reductase
FBF06_RS01610	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FBF06_RS01615	COG1360	Flagellar Motor Protein
FBF06_RS01620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FBF06_RS01640	COG1238	metal cluster binding
FBF06_RS01660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FBF06_RS01665	COG0730	response to heat
FBF06_RS01680	COG0512	Glutamine amidotransferase of anthranilate synthase
FBF06_RS01680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FBF06_RS01690	COG0133	tryptophan synthase activity
FBF06_RS01705	COG1776	CheC inhibitor of MCP methylation
FBF06_RS01705	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FBF06_RS01720	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FBF06_RS01725	COG0745	RESPONSE REGULATOR receiver
FBF06_RS01735	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FBF06_RS01750	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FBF06_RS01760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FBF06_RS01770	COG1538	Outer membrane efflux protein
FBF06_RS01780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FBF06_RS01795	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FBF06_RS01805	COG0754	glutathionylspermidine amidase activity
FBF06_RS01810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FBF06_RS01830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FBF06_RS01835	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FBF06_RS01840	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FBF06_RS01860	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FBF06_RS01890	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FBF06_RS01910	COG0579	oxidoreductase
FBF06_RS01915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FBF06_RS01950	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FBF06_RS01955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FBF06_RS01970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FBF06_RS01990	COG1053	succinate dehydrogenase
FBF06_RS01995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FBF06_RS02040	COG2353	YceI-like domain
FBF06_RS02075	COG0488	(ABC) transporter
FBF06_RS02090	COG1739	Uncharacterized protein family UPF0029
FBF06_RS02130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FBF06_RS02145	COG1028	Short-chain dehydrogenase reductase Sdr
FBF06_RS02155	COG1053	succinate dehydrogenase
FBF06_RS02160	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FBF06_RS02165	COG2048	Heterodisulfide reductase, subunit B
FBF06_RS02170	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FBF06_RS02175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FBF06_RS02180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FBF06_RS02210	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FBF06_RS02215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FBF06_RS02245	COG2121	Domain of unknown function (DUF374)
FBF06_RS02260	COG0195	Participates in both transcription termination and antitermination
FBF06_RS02270	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FBF06_RS02275	COG0612	Peptidase, M16
FBF06_RS02280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FBF06_RS02285	COG2346	COG2346, Truncated hemoglobins
FBF06_RS02300	COG0765	amino acid transport
FBF06_RS02330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FBF06_RS02335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FBF06_RS02350	COG0250	Participates in transcription elongation, termination and antitermination
FBF06_RS02355	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FBF06_RS02360	COG0081	regulation of translation
FBF06_RS02370	COG0222	ribosome binding
FBF06_RS02390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FBF06_RS02400	COG2721	sulfolactate sulfo-lyase activity
FBF06_RS02405	COG2271	Major facilitator Superfamily
FBF06_RS02410	COG1028	Short-chain dehydrogenase reductase Sdr
FBF06_RS02415	COG0738	Major facilitator superfamily
FBF06_RS02425	COG3254	rhamnose metabolic process
FBF06_RS02430	COG1012	belongs to the aldehyde dehydrogenase family
FBF06_RS02435	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FBF06_RS02440	COG0049	tRNA binding
FBF06_RS02470	COG3561	AntA/AntB antirepressor
FBF06_RS02810	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FBF06_RS02815	COG0004	ammonium transporteR
FBF06_RS02825	COG0673	inositol 2-dehydrogenase activity
FBF06_RS02840	COG0424	maF-like protein
FBF06_RS02850	COG0542	response to heat
FBF06_RS02855	COG1937	Protein conserved in bacteria
FBF06_RS02860	COG0793	Belongs to the peptidase S41A family
FBF06_RS02865	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FBF06_RS02870	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FBF06_RS02875	COG0047	phosphoribosylformylglycinamidine synthase activity
FBF06_RS02885	COG0204	Acyl-transferase
FBF06_RS02900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FBF06_RS02920	COG1677	Flagellar hook-basal body complex protein FliE
FBF06_RS02925	COG1558	bacterial-type flagellum-dependent cell motility
FBF06_RS02930	COG1815	bacterial-type flagellum-dependent cell motility
FBF06_RS02950	COG0039	L-malate dehydrogenase activity
FBF06_RS02960	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FBF06_RS02970	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FBF06_RS02970	COG0674	pyruvate-flavodoxin oxidoreductase activity
FBF06_RS02975	COG1013	pyruvate-flavodoxin oxidoreductase activity
FBF06_RS02995	COG0142	geranyltranstransferase activity
FBF06_RS03000	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FBF06_RS03015	COG0181	hydroxymethylbilane synthase activity
FBF06_RS03020	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FBF06_RS03030	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FBF06_RS03050	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FBF06_RS03080	COG1289	transmembrane transporter activity
FBF06_RS03085	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FBF06_RS03090	COG0492	ferredoxin-NADP+ reductase activity
FBF06_RS03105	COG0305	Participates in initiation and elongation during chromosome replication
FBF06_RS03160	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FBF06_RS03160	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FBF06_RS03165	COG1610	YqeY-like protein
FBF06_RS03170	COG0028	Belongs to the TPP enzyme family
FBF06_RS03175	COG0440	acetolactate synthase activity
FBF06_RS03185	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FBF06_RS03190	COG0805	protein transport
FBF06_RS03200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FBF06_RS03205	COG0494	nUDIX hydrolase
FBF06_RS03210	COG0527	aspartate kinase activity
FBF06_RS03225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FBF06_RS03230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FBF06_RS03245	COG0196	riboflavin kinase activity
FBF06_RS03250	COG2890	protein-(glutamine-N5) methyltransferase activity
FBF06_RS03265	COG2860	membrane
FBF06_RS03275	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FBF06_RS03280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FBF06_RS03285	COG0191	fructose-bisphosphate aldolase activity
FBF06_RS03305	COG0733	neurotransmitter:sodium symporter activity
FBF06_RS03310	COG2258	MOSC domain
FBF06_RS03325	COG1473	amidohydrolase
FBF06_RS03330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FBF06_RS03335	COG0577	efflux transmembrane transporter activity
FBF06_RS03335	COG1136	(ABC) transporter
FBF06_RS03340	COG1538	Outer membrane efflux protein
FBF06_RS03355	COG1696	Membrane protein involved in D-alanine export
FBF06_RS03360	COG1528	Iron-storage protein
FBF06_RS03365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FBF06_RS03370	COG0573	inorganic phosphate transmembrane transporter activity
FBF06_RS03375	COG0581	inorganic phosphate transmembrane transporter activity
FBF06_RS03395	COG0534	Mate efflux family protein
FBF06_RS03410	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FBF06_RS03420	COG0298	carbon dioxide binding
FBF06_RS03425	COG0409	Hydrogenase expression formation protein
FBF06_RS03430	COG0309	Hydrogenase expression formation protein (HypE)
FBF06_RS03435	COG0375	protein maturation
FBF06_RS03440	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FBF06_RS03445	COG3421	Type III restriction
FBF06_RS03455	COG0557	exoribonuclease II activity
FBF06_RS03460	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FBF06_RS03470	COG0758	DNA mediated transformation
FBF06_RS03490	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FBF06_RS03500	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FBF06_RS03505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FBF06_RS03510	COG0497	DNA recombination
FBF06_RS03520	COG0084	hydrolase, TatD family'
FBF06_RS03525	COG0791	NLP P60 protein
FBF06_RS03525	COG1388	LysM domain
FBF06_RS03530	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FBF06_RS03570	COG3104	oligopeptide transport
FBF06_RS03590	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FBF06_RS03615	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FBF06_RS03620	COG0802	atpase or kinase
FBF06_RS03625	COG1137	ATPase activity
FBF06_RS03630	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FBF06_RS03635	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FBF06_RS03655	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FBF06_RS03665	COG0556	nucleotide-excision repair
FBF06_RS03685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FBF06_RS03695	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FBF06_RS03705	COG0280	phosphate acetyltransferase
FBF06_RS03735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FBF06_RS03740	COG0849	cell division
FBF06_RS03745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FBF06_RS03750	COG4786	Flagellar basal body rod
FBF06_RS03755	COG4786	Flagellar basal body rod
FBF06_RS03760	COG0174	glutamine synthetase
FBF06_RS03775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FBF06_RS03785	COG0752	glycyl-tRNA synthetase alpha subunit
FBF06_RS03790	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FBF06_RS03800	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FBF06_RS03800	COG1519	Transferase
FBF06_RS03805	COG0564	pseudouridine synthase activity
FBF06_RS03810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FBF06_RS03815	COG0228	four-way junction DNA binding
FBF06_RS03820	COG1837	Belongs to the UPF0109 family
FBF06_RS03825	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FBF06_RS03845	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FBF06_RS03850	COG1393	Belongs to the ArsC family
FBF06_RS04135	COG0587	DNA-directed DNA polymerase activity
FBF06_RS04140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FBF06_RS04155	COG2890	protein-(glutamine-N5) methyltransferase activity
FBF06_RS04160	COG0501	Belongs to the peptidase M48B family
FBF06_RS04170	COG0521	Mo-molybdopterin cofactor biosynthetic process
FBF06_RS04175	COG0598	Magnesium transport protein CorA
FBF06_RS04195	COG1178	ABC-type Fe3 transport system permease component
FBF06_RS04205	COG3842	ATPase activity
FBF06_RS04270	COG4771	TonB-dependent receptor
FBF06_RS04275	COG1420	regulation of RNA biosynthetic process
FBF06_RS04300	COG0436	Aminotransferase
FBF06_RS04305	COG1045	serine acetyltransferase
FBF06_RS04310	COG1166	arginine decarboxylase activity
FBF06_RS04325	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FBF06_RS04330	COG0163	prenyltransferase activity
FBF06_RS04340	COG1464	Belongs to the NlpA lipoprotein family
FBF06_RS04345	COG1464	Belongs to the NlpA lipoprotein family
FBF06_RS04350	COG1464	Belongs to the NlpA lipoprotein family
FBF06_RS04355	COG2011	ABC-type metal ion transport system permease component
FBF06_RS04360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FBF06_RS04375	COG0210	DNA helicase
FBF06_RS04385	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FBF06_RS04395	COG0437	4 iron, 4 sulfur cluster binding
FBF06_RS04400	COG0348	domain, Protein
FBF06_RS04405	COG3043	anaerobic respiration
FBF06_RS04440	COG0788	formyltetrahydrofolate deformylase activity
FBF06_RS04445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FBF06_RS04455	COG0642	Histidine kinase
FBF06_RS04465	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FBF06_RS04480	COG1181	Belongs to the D-alanine--D-alanine ligase family
FBF06_RS04485	COG0632	four-way junction helicase activity
FBF06_RS04495	COG0728	peptidoglycan biosynthetic process
FBF06_RS04500	COG0215	cysteine-tRNA ligase activity
FBF06_RS04505	COG1132	(ABC) transporter
FBF06_RS04510	COG0167	dihydroorotate dehydrogenase activity
FBF06_RS04515	COG0612	Peptidase, M16
FBF06_RS04520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FBF06_RS04525	COG1028	Short-chain dehydrogenase reductase Sdr
FBF06_RS04540	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FBF06_RS04550	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FBF06_RS04555	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FBF06_RS04570	COG1338	Plays a role in the flagellum-specific transport system
FBF06_RS04575	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FBF06_RS04605	COG0101	tRNA pseudouridine synthase activity
FBF06_RS04610	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FBF06_RS04630	COG1757	Na H antiporter
FBF06_RS04635	COG4221	oxidoreductase activity
FBF06_RS04645	COG1049	propionate catabolic process, 2-methylcitrate cycle
FBF06_RS04650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FBF06_RS04660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FBF06_RS04660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FBF06_RS04670	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FBF06_RS04700	COG1408	metallophosphoesterase
FBF06_RS04705	COG0688	phosphatidylethanolamine metabolic process
FBF06_RS04745	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FBF06_RS04750	COG0681	Belongs to the peptidase S26 family
FBF06_RS04755	COG0303	'Molybdopterin
FBF06_RS04770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FBF06_RS04770	COG0512	Glutamine amidotransferase of anthranilate synthase
FBF06_RS04775	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FBF06_RS04780	COG0582	viral genome integration into host DNA
FBF06_RS04785	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FBF06_RS04790	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FBF06_RS04805	COG3258	Cytochrome c
FBF06_RS04830	COG2404	hydrolase activity, acting on ester bonds
FBF06_RS04835	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FBF06_RS04840	COG1959	2 iron, 2 sulfur cluster binding
FBF06_RS04845	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FBF06_RS04850	COG1674	ftsk spoiiie
FBF06_RS04850	COG1196	nuclear chromosome segregation
FBF06_RS04855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FBF06_RS04875	COG5002	protein histidine kinase activity
FBF06_RS04880	COG0745	RESPONSE REGULATOR receiver
FBF06_RS04885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FBF06_RS04895	COG1185	polyribonucleotide nucleotidyltransferase activity
FBF06_RS04895	COG0539	negative regulation of cytoplasmic translation
FBF06_RS04900	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FBF06_RS04905	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FBF06_RS04910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FBF06_RS04910	COG0072	phenylalanine-tRNA ligase activity
FBF06_RS04915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FBF06_RS04920	COG0537	adenosine 5'-monophosphoramidase activity
FBF06_RS04935	COG0765	amino acid transport
FBF06_RS04945	COG1115	amino acid carrier protein
FBF06_RS04950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FBF06_RS04955	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FBF06_RS04980	COG1999	signal sequence binding
FBF06_RS04985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FBF06_RS04990	COG0776	regulation of translation
FBF06_RS05010	COG1966	Carbon starvation protein
FBF06_RS05015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FBF06_RS05020	COG0765	amino acid transport
FBF06_RS05025	COG0765	amino acid transport
FBF06_RS05030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FBF06_RS05035	COG1126	abc transporter atp-binding protein
FBF06_RS05040	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FBF06_RS05045	COG2201	protein-glutamate methylesterase activity
FBF06_RS05070	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FBF06_RS05075	COG0012	GTP binding
FBF06_RS05085	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FBF06_RS05090	COG5016	pyruvate
FBF06_RS05090	COG0511	ligase activity, forming carbon-carbon bonds
FBF06_RS05095	COG0733	neurotransmitter:sodium symporter activity
FBF06_RS05100	COG0733	neurotransmitter:sodium symporter activity
FBF06_RS05165	COG0765	amino acid transport
FBF06_RS05175	COG0653	protein targeting
FBF06_RS05180	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FBF06_RS05190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FBF06_RS05205	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FBF06_RS05240	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FBF06_RS05260	COG0706	membrane insertase activity
FBF06_RS05275	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FBF06_RS05340	COG2195	Cleaves the N-terminal amino acid of tripeptides
FBF06_RS05345	COG0477	Major facilitator Superfamily
FBF06_RS05350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FBF06_RS05360	COG3022	response to hydroperoxide
FBF06_RS05365	COG1473	amidohydrolase
FBF06_RS05370	COG2807	transmembrane transport
FBF06_RS05385	COG2181	nitrate reductase activity
FBF06_RS05385	COG0247	lactate metabolic process
FBF06_RS05390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FBF06_RS05400	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FBF06_RS05405	COG0113	porphobilinogen synthase activity
FBF06_RS05410	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FBF06_RS05415	COG0357	Ribosomal RNA small subunit methyltransferase G
FBF06_RS05425	COG2855	membrane
FBF06_RS05430	COG0583	DNA-binding transcription factor activity
FBF06_RS05435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FBF06_RS05455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FBF06_RS05460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FBF06_RS05480	COG0343	queuine tRNA-ribosyltransferase activity
FBF06_RS05875	COG3501	Rhs element vgr protein
FBF06_RS05960	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FBF06_RS05960	COG1333	cytochrome c biogenesis protein
FBF06_RS06010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FBF06_RS06015	COG2204	response regulator
FBF06_RS06030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FBF06_RS06070	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FBF06_RS06080	COG0439	Biotin carboxylase
FBF06_RS06085	COG0772	Belongs to the SEDS family
FBF06_RS06090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FBF06_RS06110	COG0352	thiamine-phosphate diphosphorylase activity
FBF06_RS06115	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FBF06_RS06120	COG2022	thiamine diphosphate biosynthetic process
FBF06_RS06135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FBF06_RS06155	COG1193	negative regulation of DNA recombination
FBF06_RS06185	COG0516	GMP reductase activity
FBF06_RS06185	COG0517	IMP dehydrogenase activity
FBF06_RS06205	COG1058	Belongs to the CinA family
FBF06_RS06205	COG1546	Belongs to the CinA family
FBF06_RS06210	COG0456	acetyltransferase
FBF06_RS06215	COG0778	Nitroreductase
FBF06_RS06220	COG0778	Nitroreductase
FBF06_RS06230	COG0750	zinc metalloprotease
FBF06_RS06235	COG2990	Protein conserved in bacteria
FBF06_RS06245	COG0629	single-stranded DNA binding
FBF06_RS06250	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FBF06_RS06255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FBF06_RS06265	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FBF06_RS06270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FBF06_RS06315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FBF06_RS06325	COG0739	heme binding
FBF06_RS06330	COG0285	dihydrofolate synthase activity
FBF06_RS06345	COG0495	leucyl-tRNA aminoacylation
FBF06_RS06350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FBF06_RS06355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FBF06_RS06360	COG1862	Preprotein translocase
FBF06_RS06365	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FBF06_RS06370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FBF06_RS06375	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FBF06_RS06395	COG0210	DNA helicase
FBF06_RS06410	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FBF06_RS06415	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FBF06_RS06430	COG0542	response to heat
FBF06_RS06435	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FBF06_RS06445	COG2095	MarC family integral membrane protein
FBF06_RS06450	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FBF06_RS06455	COG2833	Protein of unknown function (DUF455)
FBF06_RS06460	COG1183	phosphatidylcholine synthase activity
FBF06_RS06470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FBF06_RS06480	COG0745	RESPONSE REGULATOR receiver
FBF06_RS06490	COG1086	Polysaccharide biosynthesis protein
FBF06_RS06495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FBF06_RS06500	COG0110	maltose O-acetyltransferase activity
FBF06_RS06505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FBF06_RS06510	COG0438	transferase activity, transferring glycosyl groups
FBF06_RS06520	COG0438	transferase activity, transferring glycosyl groups
FBF06_RS06525	COG1215	transferase activity, transferring glycosyl groups
FBF06_RS06530	COG0438	transferase activity, transferring glycosyl groups
FBF06_RS06535	COG1132	(ABC) transporter
FBF06_RS06540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FBF06_RS06550	COG0859	PFAM glycosyl transferase family 9
FBF06_RS06555	COG1560	Kdo2-lipid A biosynthetic process
FBF06_RS06560	COG0463	Glycosyl transferase, family 2
FBF06_RS06565	COG0438	transferase activity, transferring glycosyl groups
FBF06_RS06575	COG1216	Glycosyl transferase, family 2
FBF06_RS06585	COG1442	glycosyl transferase family 8
FBF06_RS06590	COG1216	Glycosyl transferase, family 2
FBF06_RS06610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FBF06_RS06615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FBF06_RS06630	COG2217	Heavy metal translocating P-type atpase
FBF06_RS06635	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FBF06_RS06640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FBF06_RS06655	COG2217	Heavy metal translocating P-type atpase
FBF06_RS06675	COG3610	response to peptide
FBF06_RS06685	COG0039	L-malate dehydrogenase activity
FBF06_RS06690	COG0586	Pfam SNARE associated Golgi protein
FBF06_RS06705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FBF06_RS06710	COG0217	transcriptional regulatory protein
FBF06_RS06725	COG0018	arginyl-trna synthetase
FBF06_RS06730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FBF06_RS06735	COG0194	GDP metabolic process
FBF06_RS06745	COG1684	flagellar biosynthetic protein fliR
FBF06_RS06755	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FBF06_RS06760	COG0052	Belongs to the universal ribosomal protein uS2 family
FBF06_RS06765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FBF06_RS06775	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FBF06_RS06780	COG0723	plastoquinol--plastocyanin reductase activity
FBF06_RS06785	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FBF06_RS06790	COG0445	tRNA wobble uridine modification
FBF06_RS06810	COG1301	dicarboxylic acid transport
FBF06_RS06825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FBF06_RS06840	COG1854	S-ribosylhomocysteine lyase activity
FBF06_RS06860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FBF06_RS06870	COG0356	it plays a direct role in the translocation of protons across the membrane
FBF06_RS06875	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FBF06_RS06880	COG0552	protein localization to endoplasmic reticulum
FBF06_RS06910	COG1295	ribonuclease BN
FBF06_RS06915	COG0277	FAD linked oxidase domain protein
FBF06_RS06925	COG0739	heme binding
FBF06_RS06950	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FBF06_RS06960	COG0642	Histidine kinase
FBF06_RS06965	COG0745	RESPONSE REGULATOR receiver
FBF06_RS06985	COG0642	Histidine kinase
FBF06_RS06990	COG0745	RESPONSE REGULATOR receiver
FBF06_RS06995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FBF06_RS07000	COG0484	heat shock protein binding
FBF06_RS07005	COG0789	Transcriptional regulator
FBF06_RS07010	COG0475	glutathione-regulated potassium exporter activity
FBF06_RS07010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FBF06_RS07020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FBF06_RS07025	COG0751	glycine-tRNA ligase activity
FBF06_RS07030	COG0739	heme binding
FBF06_RS07040	COG0248	Ppx GppA phosphatase
FBF06_RS07060	COG2814	Major facilitator Superfamily
FBF06_RS07075	COG0731	radical SAM domain protein
FBF06_RS07095	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FBF06_RS07095	COG0519	Catalyzes the synthesis of GMP from XMP
FBF06_RS07140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FBF06_RS07145	COG4773	Receptor
FBF06_RS07150	COG0484	heat shock protein binding
FBF06_RS07155	COG0745	RESPONSE REGULATOR receiver
FBF06_RS07160	COG0642	Histidine kinase
FBF06_RS07165	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FBF06_RS07170	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FBF06_RS07175	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
FBF06_RS07180	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FBF06_RS07185	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FBF06_RS07190	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FBF06_RS07190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FBF06_RS07205	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FBF06_RS07210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FBF06_RS07215	COG1758	RNA polymerase activity
FBF06_RS07220	COG0528	UMP kinase activity
FBF06_RS07235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FBF06_RS07250	COG0564	pseudouridine synthase activity
FBF06_RS07255	COG0772	Belongs to the SEDS family
FBF06_RS07270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FBF06_RS07275	COG0569	domain protein
FBF06_RS07280	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FBF06_RS07285	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FBF06_RS07290	COG0280	phosphate acetyltransferase
FBF06_RS07290	COG0281	malic enzyme
FBF06_RS07305	COG0439	Biotin carboxylase
FBF06_RS07310	COG0511	ligase activity, forming carbon-carbon bonds
FBF06_RS07320	COG1086	Polysaccharide biosynthesis protein
FBF06_RS07325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FBF06_RS07330	COG4310	Domain of unknown function (DUF2172)
FBF06_RS07365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FBF06_RS07415	COG1083	cytidylyl-transferase
FBF06_RS07420	COG3980	spore coat polysaccharide biosynthesis protein
FBF06_RS07425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FBF06_RS07430	COG0107	imidazoleglycerol-phosphate synthase activity
FBF06_RS07435	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FBF06_RS07445	COG2089	acid synthase
FBF06_RS07450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FBF06_RS07455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FBF06_RS07485	COG2089	acid synthase
FBF06_RS07490	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FBF06_RS07495	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FBF06_RS07505	COG1083	cytidylyl-transferase
FBF06_RS07510	COG1028	Short-chain dehydrogenase reductase Sdr
FBF06_RS07560	COG2165	general secretion pathway protein
FBF06_RS07565	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FBF06_RS07575	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FBF06_RS07580	COG0575	Belongs to the CDS family
FBF06_RS07590	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FBF06_RS07605	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FBF06_RS07610	COG4605	iron ion homeostasis
FBF06_RS07615	COG4604	ABC transporter, ATP-binding protein
FBF06_RS07620	COG4607	ABC-type enterochelin transport system periplasmic component
FBF06_RS07635	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FBF06_RS07640	COG3005	denitrification pathway
FBF06_RS07680	COG0628	permease
FBF06_RS07685	COG0114	fumarate hydratase activity
FBF06_RS07695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FBF06_RS07705	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FBF06_RS07710	COG2252	PERMEase
FBF06_RS07720	COG2853	Lipoprotein
FBF06_RS07740	COG2814	Major facilitator Superfamily
FBF06_RS07755	COG3276	selenocysteine insertion sequence binding
FBF06_RS07785	COG0753	catalase activity
FBF06_RS07795	COG2964	Protein conserved in bacteria
FBF06_RS07800	COG0251	oxidation-reduction process
FBF06_RS07825	COG1918	ferrous iron import across plasma membrane
FBF06_RS07835	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FBF06_RS07840	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FBF06_RS07855	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FBF06_RS07880	COG1580	Controls the rotational direction of flagella during chemotaxis
FBF06_RS07885	COG0736	holo-[acyl-carrier-protein] synthase activity
FBF06_RS07895	COG2124	cytochrome p450
FBF06_RS07915	COG0529	Catalyzes the synthesis of activated sulfate
FBF06_RS07920	COG1213	nucleotidyl transferase
FBF06_RS07925	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FBF06_RS07930	COG0574	Belongs to the PEP-utilizing enzyme family
FBF06_RS07930	COG3848	Pyruvate phosphate dikinase
FBF06_RS07935	COG2226	methyltransferase
FBF06_RS07995	COG1028	Short-chain dehydrogenase reductase Sdr
FBF06_RS08000	COG0318	PFAM AMP-dependent synthetase and ligase
FBF06_RS08020	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FBF06_RS08040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FBF06_RS08045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FBF06_RS08075	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FBF06_RS08075	COG0517	IMP dehydrogenase activity
FBF06_RS08120	COG0037	tRNA processing
FBF06_RS08125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FBF06_RS08140	COG0585	pseudouridine synthase activity
FBF06_RS08145	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FBF06_RS08170	COG3951	Flagellar rod assembly protein muramidase FlgJ
FBF06_RS08195	COG0730	response to heat
FBF06_RS08200	COG1459	type II secretion system
FBF06_RS08235	COG0546	phosphoglycolate phosphatase activity
FBF06_RS08245	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FBF06_RS08250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FBF06_RS08255	COG0210	DNA helicase
FBF06_RS08260	COG2887	Belongs to the helicase family. UvrD subfamily
FBF06_RS08305	COG0745	RESPONSE REGULATOR receiver
FBF06_RS08320	COG0505	Belongs to the CarA family
FBF06_RS08340	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FBF06_RS08355	COG0425	Belongs to the sulfur carrier protein TusA family
FBF06_RS08360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FBF06_RS08390	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FBF06_RS08400	COG0437	4 iron, 4 sulfur cluster binding
FBF06_RS08435	COG0314	molybdopterin synthase activity
FBF06_RS08440	COG0303	'Molybdopterin
FBF06_RS08445	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FBF06_RS08455	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FBF06_RS08470	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FBF06_RS08485	COG2992	FlgJ-related protein
FBF06_RS08495	COG0783	Belongs to the Dps family
FBF06_RS08500	COG0166	Belongs to the GPI family
FBF06_RS08510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FBF06_RS08515	COG3839	Belongs to the ABC transporter superfamily
FBF06_RS08520	COG4662	Binding-protein-dependent transport system inner membrane component
FBF06_RS08525	COG2998	abc-type tungstate transport system, permease component
FBF06_RS08530	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FBF06_RS08535	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FBF06_RS08540	COG1984	allophanate hydrolase subunit 2
FBF06_RS08550	COG2249	NAD(P)H dehydrogenase (quinone) activity
FBF06_RS08565	COG1064	alcohol dehydrogenase
FBF06_RS08580	COG0732	type I restriction modification DNA specificity domain
FBF06_RS08605	COG2814	Major facilitator Superfamily
FBF06_RS08625	COG0640	Transcriptional regulator
FBF06_RS08635	COG0798	PFAM Bile acid sodium symporter
FBF06_RS08660	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FBF06_RS08665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FBF06_RS08675	COG0839	Belongs to the complex I subunit 6 family
FBF06_RS08685	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FBF06_RS08710	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FBF06_RS08720	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FBF06_RS08735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FBF06_RS08740	COG0601	transmembrane transport
FBF06_RS08750	COG0277	FAD linked oxidase domain protein
FBF06_RS08760	COG4615	Cyclic peptide transporter
FBF06_RS08780	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FBF06_RS08785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FBF06_RS08795	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FBF06_RS08805	COG0202	RNA polymerase activity
FBF06_RS08810	COG0203	ribosomal protein L17
FBF06_RS08825	COG0131	Imidazoleglycerol-phosphate dehydratase
FBF06_RS08825	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FBF06_RS08850	COG0140	phosphoribosyl-ATP diphosphatase activity
FBF06_RS08850	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FBF06_RS08855	COG2171	N-acyltransferase activity
FBF06_RS08860	COG0489	protein tyrosine kinase activity
FBF06_RS08865	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FBF06_RS08865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FBF06_RS08875	COG2046	Belongs to the sulfate adenylyltransferase family
FBF06_RS08880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FBF06_RS08885	COG0268	Binds directly to 16S ribosomal RNA
FBF06_RS08895	COG0748	coenzyme F420 binding
FBF06_RS08900	COG4771	TonB-dependent receptor
FBF06_RS08905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FBF06_RS08910	COG1120	ATPase activity
FBF06_RS08915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FBF06_RS08925	COG0477	Major facilitator Superfamily
FBF06_RS08930	COG1194	a g-specific adenine glycosylase
FBF06_RS08960	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FBF06_RS08960	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FBF06_RS08970	COG1760	l-serine dehydratase
FBF06_RS08975	COG0814	amino acid
FBF06_RS08990	COG0811	peptide transport
FBF06_RS08995	COG0848	biopolymer transport protein
FBF06_RS09020	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FBF06_RS09025	COG0571	ribonuclease III activity
FBF06_RS09030	COG0328	RNA-DNA hybrid ribonuclease activity
FBF06_RS09040	COG0358	DNA primase activity
FBF06_RS09055	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FBF06_RS09060	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FBF06_RS09075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FBF06_RS09080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FBF06_RS09085	COG1127	ABC transporter
FBF06_RS09095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FBF06_RS09095	COG3218	ABC-type transport auxiliary lipoprotein component
FBF06_RS09105	COG0024	Methionine aminopeptidase
FBF06_RS09110	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FBF06_RS09115	COG0791	NLP P60 protein
FBF06_RS09125	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FBF06_RS09140	COG0672	)-iron permease
FBF06_RS09165	COG1136	(ABC) transporter
FBF06_RS09215	COG1793	dna ligase
FBF06_RS09230	COG0148	phosphopyruvate hydratase activity
FBF06_RS09235	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FBF06_RS09240	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FBF06_RS09245	COG1987	bacterial-type flagellum assembly
FBF06_RS09260	COG1218	3'(2'),5'-bisphosphate nucleotidase
FBF06_RS09265	COG0372	Belongs to the citrate synthase family
FBF06_RS09280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FBF06_RS09290	COG3842	ATPase activity
FBF06_RS09300	COG1175	transmembrane transport
FBF06_RS09310	COG1653	transport
FBF06_RS09325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FBF06_RS09330	COG0201	protein transport
FBF06_RS09335	COG0200	Binds to the 23S rRNA
FBF06_RS09340	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FBF06_RS09345	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FBF06_RS09350	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FBF06_RS09355	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FBF06_RS09360	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FBF06_RS09365	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FBF06_RS09370	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FBF06_RS09375	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FBF06_RS09380	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FBF06_RS09385	COG0255	Belongs to the universal ribosomal protein uL29 family
FBF06_RS09390	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FBF06_RS09395	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FBF06_RS09400	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FBF06_RS09405	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FBF06_RS09410	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FBF06_RS09415	COG0089	rRNA binding
FBF06_RS09420	COG0088	Forms part of the polypeptide exit tunnel
FBF06_RS09425	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FBF06_RS09430	COG0051	transcription antitermination factor activity, RNA binding
FBF06_RS09435	COG1187	pseudouridine synthase activity
FBF06_RS09440	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FBF06_RS09535	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FBF06_RS09545	COG1749	Flagellar hook protein flgE
FBF06_RS09550	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group