locus-tag	class	description
CSF_RS00010	COG0592	DNA-directed DNA polymerase activity
CSF_RS00015	COG0187	DNA topoisomerase II activity
CSF_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CSF_RS00045	COG5001	Diguanylate cyclase
CSF_RS00045	COG1716	ATPase activity
CSF_RS00050	COG1858	cytochrome C peroxidase
CSF_RS00065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSF_RS00080	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CSF_RS00085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CSF_RS00090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CSF_RS00095	COG1127	ABC transporter
CSF_RS00115	COG0632	four-way junction helicase activity
CSF_RS00120	COG1181	Belongs to the D-alanine--D-alanine ligase family
CSF_RS00135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CSF_RS00140	COG2964	Protein conserved in bacteria
CSF_RS00145	COG0251	oxidation-reduction process
CSF_RS00150	COG3069	C4-dicarboxylate transmembrane transporter activity
CSF_RS00155	COG0626	cystathionine gamma-synthase activity
CSF_RS00160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CSF_RS00165	COG2079	MmgE PrpD family protein
CSF_RS00180	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSF_RS00185	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CSF_RS00190	COG1472	Belongs to the glycosyl hydrolase 3 family
CSF_RS00200	COG2962	Rard protein
CSF_RS00210	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CSF_RS00225	COG0243	molybdopterin cofactor binding
CSF_RS00235	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CSF_RS00240	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CSF_RS00250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CSF_RS00255	COG0202	RNA polymerase activity
CSF_RS00260	COG0203	ribosomal protein L17
CSF_RS00290	COG1120	ATPase activity
CSF_RS00295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSF_RS00315	COG0642	Histidine kinase
CSF_RS00320	COG1053	succinate dehydrogenase
CSF_RS00325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSF_RS00330	COG2048	Heterodisulfide reductase, subunit B
CSF_RS00340	COG0284	orotidine-5'-phosphate decarboxylase activity
CSF_RS00345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CSF_RS00350	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CSF_RS00360	COG2076	Multidrug Resistance protein
CSF_RS00365	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CSF_RS00370	COG0697	spore germination
CSF_RS00375	COG1160	GTP binding
CSF_RS00380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CSF_RS00395	COG1053	succinate dehydrogenase
CSF_RS00400	COG1053	succinate dehydrogenase
CSF_RS00400	COG3976	FMN-binding domain protein
CSF_RS00420	COG0601	transmembrane transport
CSF_RS00425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSF_RS00430	COG0444	Belongs to the ABC transporter superfamily
CSF_RS00435	COG4608	Belongs to the ABC transporter superfamily
CSF_RS00485	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CSF_RS00485	COG0517	IMP dehydrogenase activity
CSF_RS00490	COG1187	pseudouridine synthase activity
CSF_RS00505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CSF_RS00515	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CSF_RS00520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSF_RS00525	COG0348	domain, Protein
CSF_RS00530	COG1309	transcriptional regulator
CSF_RS00540	COG0237	dephospho-CoA kinase activity
CSF_RS00545	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CSF_RS00555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CSF_RS00560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CSF_RS00565	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CSF_RS00570	COG1074	ATP-dependent DNA helicase activity
CSF_RS00615	COG3278	Belongs to the heme-copper respiratory oxidase family
CSF_RS00625	COG0840	transmembrane signaling receptor activity
CSF_RS00635	COG0505	Belongs to the CarA family
CSF_RS00650	COG0861	Integral membrane protein TerC family
CSF_RS00665	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CSF_RS00670	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CSF_RS00690	COG0783	Belongs to the Dps family
CSF_RS00695	COG1322	Protein conserved in bacteria
CSF_RS00705	COG4206	TonB-dependent receptor
CSF_RS00705	COG1629	transport
CSF_RS00710	COG0811	peptide transport
CSF_RS00715	COG0848	biopolymer transport protein
CSF_RS00725	COG0748	coenzyme F420 binding
CSF_RS00735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSF_RS00745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSF_RS00750	COG1120	ATPase activity
CSF_RS00755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSF_RS00760	COG4771	TonB-dependent receptor
CSF_RS00770	COG0811	peptide transport
CSF_RS00775	COG3721	Heme iron utilization protein
CSF_RS00780	COG4615	Cyclic peptide transporter
CSF_RS00785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CSF_RS00800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CSF_RS00805	COG1049	propionate catabolic process, 2-methylcitrate cycle
CSF_RS00815	COG2217	Heavy metal translocating P-type atpase
CSF_RS00820	COG2217	Heavy metal translocating P-type atpase
CSF_RS00825	COG0730	response to heat
CSF_RS00830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSF_RS00840	COG0589	response to stress
CSF_RS00850	COG2921	Belongs to the UPF0250 family
CSF_RS00855	COG0315	cyclic pyranopterin monophosphate synthase activity
CSF_RS00860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CSF_RS00880	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CSF_RS00890	COG1749	Flagellar hook protein flgE
CSF_RS00905	COG1217	gtp-binding protein TYPA
CSF_RS00940	COG1442	glycosyl transferase family 8
CSF_RS00940	COG1216	Glycosyl transferase, family 2
CSF_RS00945	COG0438	transferase activity, transferring glycosyl groups
CSF_RS00955	COG0753	catalase activity
CSF_RS00965	COG0471	metal ion transport
CSF_RS00975	COG1981	membrane
CSF_RS00985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CSF_RS00990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSF_RS00995	COG0268	Binds directly to 16S ribosomal RNA
CSF_RS01000	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CSF_RS01005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSF_RS01030	COG0628	permease
CSF_RS01055	COG0803	Belongs to the bacterial solute-binding protein 9 family
CSF_RS01065	COG1121	(ABC) transporter
CSF_RS01070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSF_RS01075	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSF_RS01080	COG0287	Prephenate dehydrogenase
CSF_RS01090	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CSF_RS01100	COG0083	homoserine kinase activity
CSF_RS01120	COG0779	Required for maturation of 30S ribosomal subunits
CSF_RS01125	COG0165	Argininosuccinate lyase
CSF_RS01140	COG0343	queuine tRNA-ribosyltransferase activity
CSF_RS01150	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CSF_RS01160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CSF_RS01165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSF_RS01170	COG0521	Mo-molybdopterin cofactor biosynthetic process
CSF_RS01185	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CSF_RS01190	COG0697	spore germination
CSF_RS01200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CSF_RS01210	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CSF_RS01220	COG0129	dihydroxy-acid dehydratase activity
CSF_RS01235	COG2056	Na+-H+ antiporter family
CSF_RS01240	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CSF_RS01245	COG0148	phosphopyruvate hydratase activity
CSF_RS01265	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CSF_RS01270	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CSF_RS01275	COG0571	ribonuclease III activity
CSF_RS01280	COG0328	RNA-DNA hybrid ribonuclease activity
CSF_RS01305	COG1741	Belongs to the pirin family
CSF_RS01310	COG0358	DNA primase activity
CSF_RS01320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CSF_RS01325	COG0484	heat shock protein binding
CSF_RS01380	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CSF_RS01390	COG0745	RESPONSE REGULATOR receiver
CSF_RS01395	COG0642	Histidine kinase
CSF_RS01400	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSF_RS01415	COG1776	CheC inhibitor of MCP methylation
CSF_RS01415	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSF_RS01430	COG0133	tryptophan synthase activity
CSF_RS01445	COG0512	Glutamine amidotransferase of anthranilate synthase
CSF_RS01445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CSF_RS01475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CSF_RS01490	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CSF_RS01495	COG1360	Flagellar Motor Protein
CSF_RS01500	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSF_RS01510	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CSF_RS01515	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CSF_RS01520	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CSF_RS01530	COG1966	Carbon starvation protein
CSF_RS01545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CSF_RS01545	COG0140	phosphoribosyl-ATP diphosphatase activity
CSF_RS01560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSF_RS01565	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CSF_RS01575	COG1157	protein secretion by the type III secretion system
CSF_RS01580	COG0302	gtp cyclohydrolase
CSF_RS01585	COG0544	peptidyl-prolyl cis-trans isomerase activity
CSF_RS01590	COG0740	serine-type endopeptidase activity
CSF_RS01600	COG0242	peptide deformylase activity
CSF_RS01605	COG0606	chelatase, subunit chli
CSF_RS01610	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CSF_RS01610	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CSF_RS01615	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CSF_RS01635	COG0450	alkyl hydroperoxide reductase
CSF_RS01640	COG0537	adenosine 5'-monophosphoramidase activity
CSF_RS01645	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CSF_RS01655	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CSF_RS01660	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CSF_RS01665	COG0539	negative regulation of cytoplasmic translation
CSF_RS01665	COG1185	polyribonucleotide nucleotidyltransferase activity
CSF_RS01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSF_RS01680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CSF_RS01685	COG0228	four-way junction DNA binding
CSF_RS01690	COG1837	Belongs to the UPF0109 family
CSF_RS01705	COG0335	large ribosomal subunit rRNA binding
CSF_RS01735	COG0840	transmembrane signaling receptor activity
CSF_RS01740	COG0587	DNA-directed DNA polymerase activity
CSF_RS01780	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CSF_RS01785	COG1090	epimerase
CSF_RS01795	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CSF_RS01800	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CSF_RS01805	COG0861	Integral membrane protein TerC family
CSF_RS01810	COG0569	domain protein
CSF_RS01815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSF_RS01825	COG2814	Major facilitator Superfamily
CSF_RS01855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CSF_RS01860	COG0708	Exodeoxyribonuclease III
CSF_RS01910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CSF_RS01915	COG0154	amidase activity
CSF_RS01920	COG0517	IMP dehydrogenase activity
CSF_RS01920	COG0516	GMP reductase activity
CSF_RS01925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSF_RS01930	COG1722	exodeoxyribonuclease VII activity
CSF_RS01935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSF_RS01945	COG0786	glutamate:sodium symporter activity
CSF_RS01950	COG0723	plastoquinol--plastocyanin reductase activity
CSF_RS01965	COG0204	Acyl-transferase
CSF_RS01965	COG0318	PFAM AMP-dependent synthetase and ligase
CSF_RS01970	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CSF_RS01975	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CSF_RS02025	COG0745	RESPONSE REGULATOR receiver
CSF_RS02050	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CSF_RS02055	COG2258	MOSC domain
CSF_RS02065	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CSF_RS02070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CSF_RS02075	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSF_RS02080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CSF_RS02085	COG1077	Cell shape determining protein MreB Mrl
CSF_RS02095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CSF_RS02115	COG0840	transmembrane signaling receptor activity
CSF_RS02130	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CSF_RS02135	COG2201	protein-glutamate methylesterase activity
CSF_RS02140	COG0840	transmembrane signaling receptor activity
CSF_RS02155	COG2022	thiamine diphosphate biosynthetic process
CSF_RS02160	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CSF_RS02175	COG0557	exoribonuclease II activity
CSF_RS02190	COG0629	single-stranded DNA binding
CSF_RS02195	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CSF_RS02200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSF_RS02210	COG0527	aspartate kinase activity
CSF_RS02225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CSF_RS02230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CSF_RS02240	COG0196	riboflavin kinase activity
CSF_RS02245	COG2890	protein-(glutamine-N5) methyltransferase activity
CSF_RS02270	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CSF_RS02275	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CSF_RS02290	COG0250	Participates in transcription elongation, termination and antitermination
CSF_RS02295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CSF_RS02305	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CSF_RS02310	COG0222	ribosome binding
CSF_RS02315	COG0085	RNA polymerase activity
CSF_RS02320	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CSF_RS02325	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CSF_RS02340	COG0724	RNA recognition motif
CSF_RS02345	COG0351	phosphomethylpyrimidine kinase
CSF_RS02355	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CSF_RS02370	COG0745	RESPONSE REGULATOR receiver
CSF_RS02375	COG0243	molybdopterin cofactor binding
CSF_RS02380	COG0437	4 iron, 4 sulfur cluster binding
CSF_RS02385	COG3301	Polysulphide reductase, NrfD
CSF_RS02390	COG0745	RESPONSE REGULATOR receiver
CSF_RS02395	COG5002	protein histidine kinase activity
CSF_RS02410	COG0277	FAD linked oxidase domain protein
CSF_RS02415	COG0052	Belongs to the universal ribosomal protein uS2 family
CSF_RS02420	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CSF_RS02425	COG1136	(ABC) transporter
CSF_RS02430	COG1684	flagellar biosynthetic protein fliR
CSF_RS02440	COG0194	GDP metabolic process
CSF_RS02445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CSF_RS02465	COG2855	membrane
CSF_RS02470	COG2863	cytochrome
CSF_RS02485	COG2217	Heavy metal translocating P-type atpase
CSF_RS02495	COG0126	phosphoglycerate kinase activity
CSF_RS02500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSF_RS02505	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CSF_RS02510	COG0799	negative regulation of ribosome biogenesis
CSF_RS02550	COG0305	Participates in initiation and elongation during chromosome replication
CSF_RS02570	COG0642	Histidine kinase
CSF_RS02575	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CSF_RS02580	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CSF_RS02585	COG0243	molybdopterin cofactor binding
CSF_RS02590	COG0437	4 iron, 4 sulfur cluster binding
CSF_RS02595	COG0348	domain, Protein
CSF_RS02600	COG3043	anaerobic respiration
CSF_RS02630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CSF_RS02635	COG2201	protein-glutamate methylesterase activity
CSF_RS02640	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSF_RS02660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CSF_RS02670	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CSF_RS02675	COG0681	Belongs to the peptidase S26 family
CSF_RS02680	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CSF_RS02685	COG0612	Peptidase, M16
CSF_RS02690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CSF_RS02710	COG5001	Diguanylate cyclase
CSF_RS02715	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CSF_RS02720	COG0298	carbon dioxide binding
CSF_RS02725	COG0409	Hydrogenase expression formation protein
CSF_RS02730	COG0309	Hydrogenase expression formation protein (HypE)
CSF_RS02735	COG0375	protein maturation
CSF_RS02740	COG0217	transcriptional regulatory protein
CSF_RS02745	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CSF_RS02750	COG0156	8-amino-7-oxononanoate synthase activity
CSF_RS02755	COG2830	Protein of unknown function (DUF452)
CSF_RS02760	COG4106	trans-aconitate 2-methyltransferase activity
CSF_RS02770	COG0280	phosphate acetyltransferase
CSF_RS02770	COG0281	malic enzyme
CSF_RS02780	COG0482	sulfurtransferase activity
CSF_RS02785	COG1611	Belongs to the LOG family
CSF_RS02790	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSF_RS02790	COG1776	CheC inhibitor of MCP methylation
CSF_RS02795	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSF_RS02810	COG0455	bacterial-type flagellum organization
CSF_RS02815	COG1419	protein localization to endoplasmic reticulum
CSF_RS02820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CSF_RS02825	COG0006	proline dipeptidase activity
CSF_RS02830	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CSF_RS02845	COG2217	Heavy metal translocating P-type atpase
CSF_RS02860	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CSF_RS02875	COG1053	succinate dehydrogenase
CSF_RS02880	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSF_RS02895	COG1012	belongs to the aldehyde dehydrogenase family
CSF_RS02905	COG1218	3'(2'),5'-bisphosphate nucleotidase
CSF_RS02910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CSF_RS02915	COG0750	zinc metalloprotease
CSF_RS02920	COG0326	Molecular chaperone. Has ATPase activity
CSF_RS02930	COG0252	asparaginase activity
CSF_RS02935	COG0745	RESPONSE REGULATOR receiver
CSF_RS02940	COG0642	Histidine kinase
CSF_RS02950	COG0586	Pfam SNARE associated Golgi protein
CSF_RS02955	COG0484	heat shock protein binding
CSF_RS02960	COG0745	RESPONSE REGULATOR receiver
CSF_RS02965	COG0642	Histidine kinase
CSF_RS02970	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CSF_RS02980	COG1959	2 iron, 2 sulfur cluster binding
CSF_RS02985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSF_RS02990	COG0840	transmembrane signaling receptor activity
CSF_RS02995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CSF_RS03000	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CSF_RS03005	COG2252	PERMEase
CSF_RS03050	COG1596	polysaccharide export
CSF_RS03050	COG1555	photosystem II stabilization
CSF_RS03125	COG1592	Rubrerythrin
CSF_RS03135	COG0166	Belongs to the GPI family
CSF_RS03150	COG1333	cytochrome c biogenesis protein
CSF_RS03150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSF_RS03160	COG1968	undecaprenyl-diphosphatase activity
CSF_RS03165	COG0352	thiamine-phosphate diphosphorylase activity
CSF_RS03175	COG1126	abc transporter atp-binding protein
CSF_RS03180	COG0765	amino acid transport
CSF_RS03185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSF_RS03190	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CSF_RS03195	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CSF_RS03225	COG0277	FAD linked oxidase domain protein
CSF_RS03230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CSF_RS03245	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CSF_RS03250	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CSF_RS03290	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CSF_RS03300	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CSF_RS03300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSF_RS03310	COG0542	response to heat
CSF_RS03315	COG0793	Belongs to the peptidase S41A family
CSF_RS03320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CSF_RS03325	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSF_RS03330	COG0047	phosphoribosylformylglycinamidine synthase activity
CSF_RS03340	COG0204	Acyl-transferase
CSF_RS03345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CSF_RS03355	COG4968	Prepilin-type N-terminal cleavage methylation domain
CSF_RS03375	COG0534	Mate efflux family protein
CSF_RS03380	COG2205	protein histidine kinase activity
CSF_RS03390	COG0488	(ABC) transporter
CSF_RS03415	COG3022	response to hydroperoxide
CSF_RS03420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSF_RS03425	COG1674	ftsk spoiiie
CSF_RS03425	COG1196	nuclear chromosome segregation
CSF_RS03440	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CSF_RS03445	COG1151	hydroxylamine reductase activity
CSF_RS03455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CSF_RS03470	COG0698	ribose 5-phosphate isomerase
CSF_RS03480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CSF_RS03485	COG0586	Pfam SNARE associated Golgi protein
CSF_RS03490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CSF_RS03505	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CSF_RS03510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSF_RS03515	COG0191	fructose-bisphosphate aldolase activity
CSF_RS03535	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CSF_RS03590	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CSF_RS03605	COG0628	permease
CSF_RS03640	COG0275	rRNA processing
CSF_RS03650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSF_RS03655	COG0849	cell division
CSF_RS03660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CSF_RS03675	COG1802	Transcriptional regulator
CSF_RS03680	COG1691	(AIR) carboxylase
CSF_RS03685	COG1606	tRNA processing
CSF_RS03690	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CSF_RS03695	COG3875	lactate racemase activity
CSF_RS03700	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CSF_RS03705	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CSF_RS03715	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CSF_RS03720	COG1862	Preprotein translocase
CSF_RS03725	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSF_RS03730	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSF_RS03740	COG0495	leucyl-tRNA aminoacylation
CSF_RS03760	COG0739	heme binding
CSF_RS03770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CSF_RS03780	COG1692	metallophosphoesterase
CSF_RS03795	COG1338	Plays a role in the flagellum-specific transport system
CSF_RS03825	COG0640	Transcriptional regulator
CSF_RS03840	COG1979	alcohol dehydrogenase
CSF_RS03845	COG0181	hydroxymethylbilane synthase activity
CSF_RS03860	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CSF_RS03865	COG0142	geranyltranstransferase activity
CSF_RS03880	COG0546	phosphoglycolate phosphatase activity
CSF_RS03900	COG0789	Transcriptional regulator
CSF_RS03905	COG0484	heat shock protein binding
CSF_RS03910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSF_RS03915	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CSF_RS03925	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CSF_RS03930	COG5016	pyruvate
CSF_RS03930	COG0511	ligase activity, forming carbon-carbon bonds
CSF_RS03935	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CSF_RS03940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CSF_RS03950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CSF_RS03965	COG0101	tRNA pseudouridine synthase activity
CSF_RS04010	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
CSF_RS04095	COG1555	photosystem II stabilization
CSF_RS04095	COG1596	polysaccharide export
CSF_RS04110	COG0500	methyltransferase
CSF_RS04125	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CSF_RS04130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CSF_RS04135	COG1663	tetraacyldisaccharide 4'-kinase activity
CSF_RS04140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CSF_RS04145	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CSF_RS04150	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CSF_RS04165	COG0542	response to heat
CSF_RS04190	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CSF_RS04220	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CSF_RS04225	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CSF_RS04230	COG1301	dicarboxylic acid transport
CSF_RS04240	COG0247	lactate metabolic process
CSF_RS04245	COG1139	Iron-sulfur cluster binding protein
CSF_RS04250	COG1556	Lactate utilization protein
CSF_RS04255	COG1620	l-lactate permease
CSF_RS04260	COG0488	(ABC) transporter
CSF_RS04280	COG3301	Polysulphide reductase, NrfD
CSF_RS04290	COG0437	4 iron, 4 sulfur cluster binding
CSF_RS04295	COG0243	molybdopterin cofactor binding
CSF_RS04335	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CSF_RS04340	COG1607	acyl-coa hydrolase
CSF_RS04345	COG0071	Belongs to the small heat shock protein (HSP20) family
CSF_RS04350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSF_RS04355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSF_RS04375	COG4591	ABC-type transport system involved in lipoprotein release permease component
CSF_RS04385	COG0582	viral genome integration into host DNA
CSF_RS04390	COG0772	Belongs to the SEDS family
CSF_RS04395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CSF_RS04400	COG0840	transmembrane signaling receptor activity
CSF_RS04405	COG1854	S-ribosylhomocysteine lyase activity
CSF_RS04410	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CSF_RS04430	COG0642	Histidine kinase
CSF_RS04445	COG0402	S-adenosylhomocysteine deaminase activity
CSF_RS04450	COG0110	maltose O-acetyltransferase activity
CSF_RS04455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSF_RS04460	COG0438	transferase activity, transferring glycosyl groups
CSF_RS04465	COG1287	oligosaccharyl transferase activity
CSF_RS04470	COG0438	transferase activity, transferring glycosyl groups
CSF_RS04475	COG0438	transferase activity, transferring glycosyl groups
CSF_RS04480	COG1216	Glycosyl transferase, family 2
CSF_RS04480	COG1442	glycosyl transferase family 8
CSF_RS04485	COG0438	transferase activity, transferring glycosyl groups
CSF_RS04490	COG3306	glycosyltransferase involved in LPS biosynthesis
CSF_RS04495	COG2244	polysaccharide biosynthetic process
CSF_RS04510	COG1793	dna ligase
CSF_RS04520	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CSF_RS04525	COG1560	Kdo2-lipid A biosynthetic process
CSF_RS04535	COG0438	transferase activity, transferring glycosyl groups
CSF_RS04545	COG0726	polysaccharide deacetylase
CSF_RS04550	COG0438	transferase activity, transferring glycosyl groups
CSF_RS04560	COG0438	transferase activity, transferring glycosyl groups
CSF_RS04570	COG0438	transferase activity, transferring glycosyl groups
CSF_RS04580	COG0726	polysaccharide deacetylase
CSF_RS04585	COG0463	Glycosyl transferase, family 2
CSF_RS04590	COG1748	Saccharopine dehydrogenase
CSF_RS04605	COG0489	protein tyrosine kinase activity
CSF_RS04610	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CSF_RS04615	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CSF_RS04615	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CSF_RS04620	COG0745	RESPONSE REGULATOR receiver
CSF_RS04625	COG2046	Belongs to the sulfate adenylyltransferase family
CSF_RS04690	COG0069	glutamate synthase activity
CSF_RS04715	COG1418	mRNA catabolic process
CSF_RS04725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSF_RS04730	COG0552	protein localization to endoplasmic reticulum
CSF_RS04735	COG1114	Component of the transport system for branched-chain amino acids
CSF_RS04745	COG0840	transmembrane signaling receptor activity
CSF_RS04750	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CSF_RS04755	COG0445	tRNA wobble uridine modification
CSF_RS04780	COG0501	Belongs to the peptidase M48B family
CSF_RS04785	COG0733	neurotransmitter:sodium symporter activity
CSF_RS04790	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CSF_RS04795	COG0137	argininosuccinate synthase activity
CSF_RS04800	COG0359	binds to the 23S rRNA
CSF_RS04805	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CSF_RS04810	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CSF_RS04815	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CSF_RS04845	COG1459	type II secretion system
CSF_RS04855	COG1496	oxidoreductase activity
CSF_RS04860	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CSF_RS04865	COG1959	2 iron, 2 sulfur cluster binding
CSF_RS04870	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSF_RS04875	COG2404	hydrolase activity, acting on ester bonds
CSF_RS05055	COG3210	domain, Protein
CSF_RS05060	COG2831	hemolysin activation secretion protein
CSF_RS05075	COG1283	sodium-dependent phosphate transmembrane transporter activity
CSF_RS05080	COG0612	Peptidase, M16
CSF_RS05100	COG1193	negative regulation of DNA recombination
CSF_RS05105	COG3287	FIST C domain
CSF_RS05105	COG2200	EAL domain
CSF_RS05105	COG2199	diguanylate cyclase activity
CSF_RS05110	COG1280	lysine exporter protein (LysE YggA)
CSF_RS05115	COG0251	oxidation-reduction process
CSF_RS05155	COG0519	Catalyzes the synthesis of GMP from XMP
CSF_RS05180	COG1546	Belongs to the CinA family
CSF_RS05180	COG1058	Belongs to the CinA family
CSF_RS05190	COG2861	carbohydrate metabolic process
CSF_RS05215	COG0134	indole-3-glycerol-phosphate synthase activity
CSF_RS05225	COG0727	PFAM Uncharacterised protein family (UPF0153)
CSF_RS05230	COG2813	Specifically methylates the guanine in position
CSF_RS05240	COG2072	flavoprotein involved in K transport
CSF_RS05245	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CSF_RS05265	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CSF_RS05290	COG3951	Flagellar rod assembly protein muramidase FlgJ
CSF_RS05315	COG1984	allophanate hydrolase subunit 2
CSF_RS05320	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CSF_RS05325	COG1914	H( )-stimulated, divalent metal cation uptake system
CSF_RS05330	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CSF_RS05335	COG0390	transport system, permease component
CSF_RS05340	COG0398	Pfam SNARE associated Golgi protein
CSF_RS05375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSF_RS05415	COG1464	Belongs to the NlpA lipoprotein family
CSF_RS05425	COG2011	ABC-type metal ion transport system permease component
CSF_RS05430	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSF_RS05435	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSF_RS05445	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CSF_RS05460	COG0528	UMP kinase activity
CSF_RS05475	COG2884	Cell division ATP-binding protein ftsE
CSF_RS05480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CSF_RS05490	COG0564	pseudouridine synthase activity
CSF_RS05495	COG0772	Belongs to the SEDS family
CSF_RS05505	COG0243	molybdopterin cofactor binding
CSF_RS05520	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CSF_RS05525	COG0049	tRNA binding
CSF_RS05530	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CSF_RS05535	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CSF_RS05545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CSF_RS05550	COG2957	Belongs to the agmatine deiminase family
CSF_RS05555	COG0840	transmembrane signaling receptor activity
CSF_RS05560	COG0443	Heat shock 70 kDa protein
CSF_RS05565	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CSF_RS05570	COG1420	regulation of RNA biosynthetic process
CSF_RS05590	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CSF_RS05590	COG0674	pyruvate-flavodoxin oxidoreductase activity
CSF_RS05600	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CSF_RS05605	COG0045	succinate-CoA ligase (ADP-forming) activity
CSF_RS05615	COG1538	Outer membrane efflux protein
CSF_RS05625	COG0588	phosphoglycerate mutase activity
CSF_RS05630	COG2833	Protein of unknown function (DUF455)
CSF_RS05645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CSF_RS05660	COG0163	prenyltransferase activity
CSF_RS05665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CSF_RS05670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CSF_RS05675	COG0124	histidyl-tRNA synthetase
CSF_RS05680	COG1166	arginine decarboxylase activity
CSF_RS05685	COG1045	serine acetyltransferase
CSF_RS05700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CSF_RS05705	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CSF_RS05710	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSF_RS05715	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CSF_RS05725	COG2378	regulation of single-species biofilm formation
CSF_RS05815	COG1301	dicarboxylic acid transport
CSF_RS05820	COG1580	Controls the rotational direction of flagella during chemotaxis
CSF_RS05825	COG0736	holo-[acyl-carrier-protein] synthase activity
CSF_RS05830	COG0728	peptidoglycan biosynthetic process
CSF_RS05835	COG0215	cysteine-tRNA ligase activity
CSF_RS05840	COG1132	(ABC) transporter
CSF_RS05845	COG0167	dihydroorotate dehydrogenase activity
CSF_RS05850	COG0612	Peptidase, M16
CSF_RS05855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSF_RS05860	COG1028	Short-chain dehydrogenase reductase Sdr
CSF_RS05865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CSF_RS05870	COG1815	bacterial-type flagellum-dependent cell motility
CSF_RS05880	COG1677	Flagellar hook-basal body complex protein FliE
CSF_RS05885	COG0768	penicillin binding
CSF_RS05895	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CSF_RS05910	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CSF_RS05920	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CSF_RS05930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CSF_RS05935	COG2176	DNA-directed DNA polymerase activity
CSF_RS05955	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CSF_RS05960	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CSF_RS05965	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CSF_RS05970	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CSF_RS05980	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CSF_RS05990	COG0688	phosphatidylethanolamine metabolic process
CSF_RS05995	COG1408	metallophosphoesterase
CSF_RS06005	COG0440	acetolactate synthase activity
CSF_RS06010	COG0028	Belongs to the TPP enzyme family
CSF_RS06020	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CSF_RS06025	COG0280	phosphate acetyltransferase
CSF_RS06030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CSF_RS06035	COG1929	Belongs to the glycerate kinase type-1 family
CSF_RS06040	COG2610	gluconate transmembrane transporter activity
CSF_RS06055	COG0716	FMN binding
CSF_RS06065	COG0314	molybdopterin synthase activity
CSF_RS06085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSF_RS06085	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSF_RS06095	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CSF_RS06110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSF_RS06115	COG1757	Na H antiporter
CSF_RS06120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CSF_RS06140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSF_RS06160	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CSF_RS06165	COG2067	long-chain fatty acid transport protein
CSF_RS06170	COG1222	aaa ATPase
CSF_RS06175	COG0747	negative chemotaxis
CSF_RS06180	COG0601	transmembrane transport
CSF_RS06185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSF_RS06200	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CSF_RS06210	COG1137	ATPase activity
CSF_RS06215	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CSF_RS06220	COG0484	heat shock protein binding
CSF_RS06235	COG0439	Biotin carboxylase
CSF_RS06250	COG0848	biopolymer transport protein
CSF_RS06255	COG0811	peptide transport
CSF_RS06260	COG4771	TonB-dependent receptor
CSF_RS06265	COG4607	ABC-type enterochelin transport system periplasmic component
CSF_RS06270	COG4604	ABC transporter, ATP-binding protein
CSF_RS06275	COG4605	iron ion homeostasis
CSF_RS06280	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSF_RS06310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CSF_RS06325	COG0564	pseudouridine synthase activity
CSF_RS06330	COG1519	Transferase
CSF_RS06330	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CSF_RS06340	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CSF_RS06345	COG0752	glycyl-tRNA synthetase alpha subunit
CSF_RS06360	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CSF_RS06365	COG0826	peptidase U32
CSF_RS06375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CSF_RS06380	COG0174	glutamine synthetase
CSF_RS06385	COG0195	Participates in both transcription termination and antitermination
CSF_RS06395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CSF_RS06400	COG2121	Domain of unknown function (DUF374)
CSF_RS06420	COG0037	tRNA processing
CSF_RS06425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CSF_RS06430	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CSF_RS06435	COG1104	cysteine desulfurase activity
CSF_RS06440	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CSF_RS06440	COG2906	2 iron, 2 sulfur cluster binding
CSF_RS06440	COG0822	iron-sulfur transferase activity
CSF_RS06510	COG0439	Biotin carboxylase
CSF_RS06515	COG0511	ligase activity, forming carbon-carbon bonds
CSF_RS06520	COG0717	Belongs to the dCTP deaminase family
CSF_RS06525	COG1086	Polysaccharide biosynthesis protein
CSF_RS06530	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CSF_RS06535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CSF_RS06545	COG0569	domain protein
CSF_RS06545	COG0475	glutathione-regulated potassium exporter activity
CSF_RS06550	COG0372	Belongs to the citrate synthase family
CSF_RS06565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSF_RS06575	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CSF_RS06580	COG0113	porphobilinogen synthase activity
CSF_RS06585	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CSF_RS06605	COG0501	Belongs to the peptidase M48B family
CSF_RS06610	COG0668	transmembrane transport
CSF_RS06620	COG0776	regulation of translation
CSF_RS06625	COG1999	signal sequence binding
CSF_RS06640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CSF_RS06645	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CSF_RS06660	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CSF_RS06670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CSF_RS06685	COG3041	Addiction module toxin RelE StbE family
CSF_RS06745	COG0582	viral genome integration into host DNA
CSF_RS06765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CSF_RS06770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CSF_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
CSF_RS06780	COG0179	Fumarylacetoacetate (FAA) hydrolase
CSF_RS06790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CSF_RS06795	COG2860	membrane
CSF_RS06800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CSF_RS06805	COG1183	phosphatidylcholine synthase activity
CSF_RS06810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSF_RS06815	COG2264	protein methyltransferase activity
CSF_RS06820	COG0745	RESPONSE REGULATOR receiver
CSF_RS06825	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CSF_RS06830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CSF_RS06835	COG1086	Polysaccharide biosynthesis protein
CSF_RS06840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CSF_RS06855	COG4786	Flagellar basal body rod
CSF_RS06860	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CSF_RS06865	COG0594	ribonuclease P activity
CSF_RS06870	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CSF_RS06875	COG0706	membrane insertase activity
CSF_RS06885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CSF_RS06890	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSF_RS06895	COG0484	heat shock protein binding
CSF_RS06915	COG0840	transmembrane signaling receptor activity
CSF_RS06930	COG0739	heme binding
CSF_RS06935	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CSF_RS06955	COG0556	nucleotide-excision repair
CSF_RS06960	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CSF_RS06970	COG0066	3-isopropylmalate dehydratase activity
CSF_RS06975	COG0473	3-isopropylmalate dehydrogenase activity
CSF_RS06990	COG0617	tRNA 3'-terminal CCA addition
CSF_RS06995	COG0788	formyltetrahydrofolate deformylase activity
CSF_RS07010	COG0751	glycine-tRNA ligase activity
CSF_RS07015	COG0745	RESPONSE REGULATOR receiver
CSF_RS07030	COG3976	FMN-binding domain protein
CSF_RS07030	COG1053	succinate dehydrogenase
CSF_RS07035	COG0469	pyruvate kinase activity
CSF_RS07040	COG0579	oxidoreductase
CSF_RS07045	COG0471	metal ion transport
CSF_RS07055	COG1271	oxidase subunit
CSF_RS07075	COG3258	Cytochrome c
CSF_RS07095	COG0824	Thioesterase
CSF_RS07105	COG1573	uracil-dna glycosylase
CSF_RS07110	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CSF_RS07115	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CSF_RS07130	COG0497	DNA recombination
CSF_RS07140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CSF_RS07145	COG0563	adenylate kinase activity
CSF_RS07150	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CSF_RS07155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSF_RS07160	COG1216	Glycosyl transferase, family 2
CSF_RS07170	COG1216	Glycosyl transferase, family 2
CSF_RS07170	COG1442	glycosyl transferase family 8
CSF_RS07180	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CSF_RS07210	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CSF_RS07215	COG0805	protein transport
CSF_RS07220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CSF_RS07225	COG0778	Nitroreductase
CSF_RS07230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSF_RS07240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CSF_RS07245	COG0754	glutathionylspermidine amidase activity
CSF_RS07250	COG1115	amino acid carrier protein
CSF_RS07270	COG0351	phosphomethylpyrimidine kinase
CSF_RS07275	COG3839	Belongs to the ABC transporter superfamily
CSF_RS07280	COG4662	Binding-protein-dependent transport system inner membrane component
CSF_RS07285	COG2998	abc-type tungstate transport system, permease component
CSF_RS07290	COG1739	Uncharacterized protein family UPF0029
CSF_RS07300	COG1570	exodeoxyribonuclease VII activity
CSF_RS07320	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CSF_RS07330	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSF_RS07340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CSF_RS07345	COG0077	Prephenate dehydratase
CSF_RS07345	COG1605	Chorismate mutase
CSF_RS07350	COG0019	diaminopimelate decarboxylase activity
CSF_RS07360	COG0193	aminoacyl-tRNA hydrolase activity
CSF_RS07385	COG0835	chemotaxis
CSF_RS07390	COG0643	Histidine kinase
CSF_RS07390	COG0784	Response regulator, receiver
CSF_RS07390	COG2198	Histidine kinase
CSF_RS07395	COG0835	chemotaxis
CSF_RS07395	COG0784	Response regulator, receiver
CSF_RS07405	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CSF_RS07410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CSF_RS07430	COG0716	FMN binding
CSF_RS07435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSF_RS07440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSF_RS07445	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CSF_RS07450	COG0575	Belongs to the CDS family
CSF_RS07465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CSF_RS07475	COG1749	Flagellar hook protein flgE
CSF_RS07480	COG1760	l-serine dehydratase
CSF_RS07485	COG0814	amino acid
CSF_RS07495	COG2703	oxygen carrier activity
CSF_RS07500	COG0668	transmembrane transport
CSF_RS07505	COG0288	reversible hydration of carbon dioxide
CSF_RS07510	COG0670	Belongs to the BI1 family
CSF_RS07515	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CSF_RS07525	COG0233	cytoplasmic translational termination
CSF_RS07530	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CSF_RS07540	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CSF_RS07550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CSF_RS07555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CSF_RS07560	COG1047	Peptidyl-prolyl cis-trans
CSF_RS07565	COG0492	ferredoxin-NADP+ reductase activity
CSF_RS07570	COG3118	belongs to the thioredoxin family
CSF_RS07575	COG0792	nuclease activity
CSF_RS07580	COG0460	homoserine dehydrogenase
CSF_RS07585	COG0436	Aminotransferase
CSF_RS07605	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CSF_RS07610	COG0254	rRNA binding
CSF_RS07615	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSF_RS07635	COG0602	queuosine metabolic process
CSF_RS07640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CSF_RS07695	COG2233	PERMEase
CSF_RS07705	COG0105	UTP biosynthetic process
CSF_RS07715	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CSF_RS07720	COG0416	fatty acid biosynthetic process
CSF_RS07725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CSF_RS07760	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CSF_RS07775	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CSF_RS07780	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CSF_RS07795	COG0561	phosphatase activity
CSF_RS07805	COG1388	LysM domain
CSF_RS07805	COG0741	lytic transglycosylase activity
CSF_RS07810	COG0084	hydrolase, TatD family'
CSF_RS07840	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CSF_RS07855	COG0733	neurotransmitter:sodium symporter activity
CSF_RS07860	COG0733	neurotransmitter:sodium symporter activity
CSF_RS07865	COG0733	neurotransmitter:sodium symporter activity
CSF_RS07870	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CSF_RS07880	COG4773	Receptor
CSF_RS07885	COG1596	polysaccharide export
CSF_RS07885	COG1555	photosystem II stabilization
CSF_RS07915	COG0778	Nitroreductase
CSF_RS07925	COG1253	flavin adenine dinucleotide binding
CSF_RS07935	COG3260	NADH ubiquinone oxidoreductase 20
CSF_RS07945	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CSF_RS07945	COG3261	NADH dehydrogenase
CSF_RS07950	COG0651	ATP synthesis coupled electron transport
CSF_RS07955	COG4237	Hydrogenase 4 membrane
CSF_RS07960	COG0650	Formate hydrogenlyase subunit 4
CSF_RS07965	COG0651	ATP synthesis coupled electron transport
CSF_RS07970	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSF_RS07975	COG4783	chaperone-mediated protein folding
CSF_RS07980	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CSF_RS07985	COG3005	denitrification pathway
CSF_RS07990	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CSF_RS07995	COG1027	Aspartate ammonia-lyase
CSF_RS08000	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CSF_RS08010	COG0840	transmembrane signaling receptor activity
CSF_RS08015	COG0840	transmembrane signaling receptor activity
CSF_RS08025	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSF_RS08030	COG3069	C4-dicarboxylate transmembrane transporter activity
CSF_RS08035	COG3340	Belongs to the peptidase S51 family
CSF_RS08045	COG0252	asparaginase activity
CSF_RS08060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CSF_RS08065	COG0540	Belongs to the ATCase OTCase family
CSF_RS08070	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CSF_RS08075	COG0840	transmembrane signaling receptor activity
CSF_RS08080	COG1083	cytidylyl-transferase
CSF_RS08090	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CSF_RS08140	COG1028	Short-chain dehydrogenase reductase Sdr
CSF_RS08145	COG0318	PFAM AMP-dependent synthetase and ligase
CSF_RS08150	COG2089	acid synthase
CSF_RS08175	COG0243	molybdopterin cofactor binding
CSF_RS08185	COG0437	4 iron, 4 sulfur cluster binding
CSF_RS08195	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CSF_RS08205	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CSF_RS08220	COG0542	response to heat
CSF_RS08245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSF_RS08255	COG0481	GTPase activity
CSF_RS08295	COG2204	response regulator
CSF_RS08300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSF_RS08305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CSF_RS08310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSF_RS08320	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CSF_RS08375	COG2204	response regulator
CSF_RS08385	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CSF_RS08390	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CSF_RS08400	COG2885	chlorophyll binding
CSF_RS08415	COG0848	biopolymer transport protein
CSF_RS08420	COG0811	peptide transport
CSF_RS08430	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CSF_RS08435	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CSF_RS08440	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CSF_RS08445	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CSF_RS08450	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CSF_RS08460	COG1475	DNA binding
CSF_RS08465	COG1192	Involved in chromosome partitioning
CSF_RS08475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CSF_RS08485	COG0437	4 iron, 4 sulfur cluster binding
CSF_RS08505	COG1921	L-seryl-tRNASec selenium transferase activity
CSF_RS08520	COG1918	ferrous iron import across plasma membrane
CSF_RS08595	COG1007	ATP synthesis coupled electron transport
CSF_RS08600	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSF_RS08605	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSF_RS08615	COG0839	Belongs to the complex I subunit 6 family
CSF_RS08620	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSF_RS08645	COG0649	NAD binding
CSF_RS08655	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSF_RS08660	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSF_RS08665	COG0024	Methionine aminopeptidase
CSF_RS08670	COG0201	protein transport
CSF_RS08675	COG0200	Binds to the 23S rRNA
CSF_RS08680	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CSF_RS08685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CSF_RS08695	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CSF_RS08710	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CSF_RS08715	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CSF_RS08720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CSF_RS08725	COG0255	Belongs to the universal ribosomal protein uL29 family
CSF_RS08730	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CSF_RS08735	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CSF_RS08740	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CSF_RS08745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CSF_RS08750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CSF_RS08755	COG0089	rRNA binding
CSF_RS08765	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CSF_RS08770	COG0051	transcription antitermination factor activity, RNA binding
CSF_RS08785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CSF_RS08790	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CSF_RS08805	COG0142	geranyltranstransferase activity
CSF_RS08810	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CSF_RS08825	COG0243	molybdopterin cofactor binding
CSF_RS08830	COG0437	4 iron, 4 sulfur cluster binding
CSF_RS08860	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSF_RS08865	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CSF_RS08870	COG0581	inorganic phosphate transmembrane transporter activity
CSF_RS08875	COG0573	inorganic phosphate transmembrane transporter activity
CSF_RS08880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CSF_RS08895	COG1131	(ABC) transporter
CSF_RS08905	COG0848	biopolymer transport protein
CSF_RS08910	COG0811	peptide transport
CSF_RS08935	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CSF_RS08935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CSF_RS08945	COG0107	imidazoleglycerol-phosphate synthase activity
CSF_RS08955	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CSF_RS08970	COG0564	pseudouridine synthase activity
CSF_RS08975	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group