locus-tag	class	description
CSPUT_RS00010	COG0592	DNA-directed DNA polymerase activity
CSPUT_RS00015	COG0187	DNA topoisomerase II activity
CSPUT_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CSPUT_RS00045	COG1716	ATPase activity
CSPUT_RS00045	COG5001	Diguanylate cyclase
CSPUT_RS00050	COG1858	cytochrome C peroxidase
CSPUT_RS00065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSPUT_RS00080	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CSPUT_RS00085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CSPUT_RS00090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CSPUT_RS00095	COG1127	ABC transporter
CSPUT_RS00115	COG0632	four-way junction helicase activity
CSPUT_RS00120	COG1181	Belongs to the D-alanine--D-alanine ligase family
CSPUT_RS00135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CSPUT_RS00140	COG2964	Protein conserved in bacteria
CSPUT_RS00145	COG0251	oxidation-reduction process
CSPUT_RS00150	COG2610	gluconate transmembrane transporter activity
CSPUT_RS00155	COG3048	D-serine ammonia-lyase activity
CSPUT_RS00165	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSPUT_RS00170	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CSPUT_RS00175	COG1472	Belongs to the glycosyl hydrolase 3 family
CSPUT_RS00185	COG2962	Rard protein
CSPUT_RS00190	COG3706	GGDEF domain
CSPUT_RS00195	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CSPUT_RS00210	COG0243	molybdopterin cofactor binding
CSPUT_RS00220	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CSPUT_RS00225	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CSPUT_RS00235	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CSPUT_RS00240	COG0202	RNA polymerase activity
CSPUT_RS00245	COG0203	ribosomal protein L17
CSPUT_RS00250	COG0840	transmembrane signaling receptor activity
CSPUT_RS00280	COG2197	response regulator
CSPUT_RS00285	COG0642	Histidine kinase
CSPUT_RS00290	COG1053	succinate dehydrogenase
CSPUT_RS00295	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSPUT_RS00300	COG2048	Heterodisulfide reductase, subunit B
CSPUT_RS00310	COG0284	orotidine-5'-phosphate decarboxylase activity
CSPUT_RS00315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CSPUT_RS00320	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CSPUT_RS00325	COG2076	Multidrug Resistance protein
CSPUT_RS00335	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CSPUT_RS00340	COG0697	spore germination
CSPUT_RS00345	COG1160	GTP binding
CSPUT_RS00350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CSPUT_RS00365	COG1053	succinate dehydrogenase
CSPUT_RS00370	COG3976	FMN-binding domain protein
CSPUT_RS00370	COG1053	succinate dehydrogenase
CSPUT_RS00390	COG0601	transmembrane transport
CSPUT_RS00395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSPUT_RS00400	COG1126	abc transporter atp-binding protein
CSPUT_RS00405	COG4172	Belongs to the ABC transporter superfamily
CSPUT_RS00450	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CSPUT_RS00455	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CSPUT_RS00455	COG0517	IMP dehydrogenase activity
CSPUT_RS00460	COG1187	pseudouridine synthase activity
CSPUT_RS00475	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CSPUT_RS00485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CSPUT_RS00490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSPUT_RS00495	COG0348	domain, Protein
CSPUT_RS00500	COG1309	transcriptional regulator
CSPUT_RS00510	COG0237	dephospho-CoA kinase activity
CSPUT_RS00515	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CSPUT_RS00525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CSPUT_RS00530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CSPUT_RS00535	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CSPUT_RS00540	COG1074	ATP-dependent DNA helicase activity
CSPUT_RS00585	COG3278	Belongs to the heme-copper respiratory oxidase family
CSPUT_RS00595	COG0840	transmembrane signaling receptor activity
CSPUT_RS00605	COG0505	Belongs to the CarA family
CSPUT_RS00620	COG0861	Integral membrane protein TerC family
CSPUT_RS00635	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CSPUT_RS00640	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CSPUT_RS00660	COG0783	Belongs to the Dps family
CSPUT_RS00665	COG1322	Protein conserved in bacteria
CSPUT_RS00675	COG4206	TonB-dependent receptor
CSPUT_RS00675	COG1629	transport
CSPUT_RS00680	COG0811	peptide transport
CSPUT_RS00685	COG0848	biopolymer transport protein
CSPUT_RS00695	COG0748	coenzyme F420 binding
CSPUT_RS00705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSPUT_RS00715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSPUT_RS00720	COG1120	ATPase activity
CSPUT_RS00725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSPUT_RS00730	COG4771	TonB-dependent receptor
CSPUT_RS00740	COG0811	peptide transport
CSPUT_RS00745	COG3721	Heme iron utilization protein
CSPUT_RS00750	COG4615	Cyclic peptide transporter
CSPUT_RS00755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CSPUT_RS00770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CSPUT_RS00800	COG1049	propionate catabolic process, 2-methylcitrate cycle
CSPUT_RS00810	COG2217	Heavy metal translocating P-type atpase
CSPUT_RS00815	COG2217	Heavy metal translocating P-type atpase
CSPUT_RS00820	COG0730	response to heat
CSPUT_RS00825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSPUT_RS00830	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CSPUT_RS00830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CSPUT_RS00835	COG0589	response to stress
CSPUT_RS00845	COG2921	Belongs to the UPF0250 family
CSPUT_RS00850	COG0315	cyclic pyranopterin monophosphate synthase activity
CSPUT_RS00855	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CSPUT_RS00875	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CSPUT_RS00885	COG1749	Flagellar hook protein flgE
CSPUT_RS00900	COG1217	gtp-binding protein TYPA
CSPUT_RS00910	COG4771	TonB-dependent receptor
CSPUT_RS00920	COG0471	metal ion transport
CSPUT_RS00935	COG1981	membrane
CSPUT_RS00945	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CSPUT_RS00950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSPUT_RS00955	COG0268	Binds directly to 16S ribosomal RNA
CSPUT_RS00960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CSPUT_RS00990	COG0628	permease
CSPUT_RS01015	COG0803	Belongs to the bacterial solute-binding protein 9 family
CSPUT_RS01025	COG1121	(ABC) transporter
CSPUT_RS01030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSPUT_RS01035	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSPUT_RS01040	COG0287	Prephenate dehydrogenase
CSPUT_RS01050	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CSPUT_RS01060	COG0083	homoserine kinase activity
CSPUT_RS01080	COG0779	Required for maturation of 30S ribosomal subunits
CSPUT_RS01085	COG0165	Argininosuccinate lyase
CSPUT_RS01100	COG0343	queuine tRNA-ribosyltransferase activity
CSPUT_RS01110	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CSPUT_RS01120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CSPUT_RS01125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSPUT_RS01130	COG0521	Mo-molybdopterin cofactor biosynthetic process
CSPUT_RS01150	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CSPUT_RS01155	COG0697	spore germination
CSPUT_RS01170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CSPUT_RS01175	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CSPUT_RS01185	COG0129	dihydroxy-acid dehydratase activity
CSPUT_RS01195	COG2056	Na+-H+ antiporter family
CSPUT_RS01200	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CSPUT_RS01205	COG0148	phosphopyruvate hydratase activity
CSPUT_RS01225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CSPUT_RS01230	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CSPUT_RS01235	COG0571	ribonuclease III activity
CSPUT_RS01240	COG0328	RNA-DNA hybrid ribonuclease activity
CSPUT_RS01275	COG0358	DNA primase activity
CSPUT_RS01285	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CSPUT_RS01290	COG0484	heat shock protein binding
CSPUT_RS01325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CSPUT_RS01330	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CSPUT_RS01330	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CSPUT_RS01335	COG0606	chelatase, subunit chli
CSPUT_RS01340	COG0242	peptide deformylase activity
CSPUT_RS01350	COG0740	serine-type endopeptidase activity
CSPUT_RS01355	COG0544	peptidyl-prolyl cis-trans isomerase activity
CSPUT_RS01360	COG0302	gtp cyclohydrolase
CSPUT_RS01365	COG1157	protein secretion by the type III secretion system
CSPUT_RS01375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CSPUT_RS01380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSPUT_RS01395	COG0140	phosphoribosyl-ATP diphosphatase activity
CSPUT_RS01395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CSPUT_RS01410	COG1966	Carbon starvation protein
CSPUT_RS01420	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CSPUT_RS01425	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CSPUT_RS01430	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CSPUT_RS01440	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSPUT_RS01445	COG1360	Flagellar Motor Protein
CSPUT_RS01450	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CSPUT_RS01460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CSPUT_RS01490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CSPUT_RS01490	COG0512	Glutamine amidotransferase of anthranilate synthase
CSPUT_RS01505	COG0133	tryptophan synthase activity
CSPUT_RS01520	COG1776	CheC inhibitor of MCP methylation
CSPUT_RS01520	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSPUT_RS01535	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSPUT_RS01540	COG0642	Histidine kinase
CSPUT_RS01545	COG0745	RESPONSE REGULATOR receiver
CSPUT_RS01555	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CSPUT_RS01600	COG0450	alkyl hydroperoxide reductase
CSPUT_RS01605	COG0537	adenosine 5'-monophosphoramidase activity
CSPUT_RS01610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CSPUT_RS01620	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CSPUT_RS01625	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CSPUT_RS01630	COG1185	polyribonucleotide nucleotidyltransferase activity
CSPUT_RS01630	COG0539	negative regulation of cytoplasmic translation
CSPUT_RS01640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSPUT_RS01645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CSPUT_RS01650	COG0228	four-way junction DNA binding
CSPUT_RS01655	COG1837	Belongs to the UPF0109 family
CSPUT_RS01670	COG0335	large ribosomal subunit rRNA binding
CSPUT_RS01700	COG0840	transmembrane signaling receptor activity
CSPUT_RS01705	COG0587	DNA-directed DNA polymerase activity
CSPUT_RS01745	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CSPUT_RS01750	COG1090	epimerase
CSPUT_RS01760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CSPUT_RS01765	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CSPUT_RS01770	COG0861	Integral membrane protein TerC family
CSPUT_RS01775	COG0569	domain protein
CSPUT_RS01780	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSPUT_RS01790	COG2814	Major facilitator Superfamily
CSPUT_RS01825	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CSPUT_RS01830	COG0708	Exodeoxyribonuclease III
CSPUT_RS01880	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CSPUT_RS01885	COG0154	amidase activity
CSPUT_RS01890	COG0516	GMP reductase activity
CSPUT_RS01890	COG0517	IMP dehydrogenase activity
CSPUT_RS01895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSPUT_RS01900	COG1722	exodeoxyribonuclease VII activity
CSPUT_RS01905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSPUT_RS01910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSPUT_RS01915	COG0786	glutamate:sodium symporter activity
CSPUT_RS01920	COG0723	plastoquinol--plastocyanin reductase activity
CSPUT_RS01935	COG0318	PFAM AMP-dependent synthetase and ligase
CSPUT_RS01935	COG0204	Acyl-transferase
CSPUT_RS01940	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CSPUT_RS01945	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CSPUT_RS01995	COG0745	RESPONSE REGULATOR receiver
CSPUT_RS02020	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CSPUT_RS02025	COG2258	MOSC domain
CSPUT_RS02035	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CSPUT_RS02040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CSPUT_RS02045	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSPUT_RS02050	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CSPUT_RS02055	COG1077	Cell shape determining protein MreB Mrl
CSPUT_RS02065	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CSPUT_RS02085	COG0840	transmembrane signaling receptor activity
CSPUT_RS02100	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CSPUT_RS02105	COG2201	protein-glutamate methylesterase activity
CSPUT_RS02110	COG0840	transmembrane signaling receptor activity
CSPUT_RS02125	COG2022	thiamine diphosphate biosynthetic process
CSPUT_RS02130	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CSPUT_RS02145	COG0557	exoribonuclease II activity
CSPUT_RS02160	COG0629	single-stranded DNA binding
CSPUT_RS02165	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CSPUT_RS02170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSPUT_RS02180	COG0527	aspartate kinase activity
CSPUT_RS02195	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CSPUT_RS02200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CSPUT_RS02210	COG0196	riboflavin kinase activity
CSPUT_RS02215	COG2890	protein-(glutamine-N5) methyltransferase activity
CSPUT_RS02240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CSPUT_RS02245	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CSPUT_RS02260	COG0250	Participates in transcription elongation, termination and antitermination
CSPUT_RS02265	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CSPUT_RS02275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CSPUT_RS02280	COG0222	ribosome binding
CSPUT_RS02285	COG0085	RNA polymerase activity
CSPUT_RS02290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CSPUT_RS02295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CSPUT_RS02310	COG0724	RNA recognition motif
CSPUT_RS02315	COG0351	phosphomethylpyrimidine kinase
CSPUT_RS02325	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CSPUT_RS02340	COG0745	RESPONSE REGULATOR receiver
CSPUT_RS02345	COG0243	molybdopterin cofactor binding
CSPUT_RS02350	COG0437	4 iron, 4 sulfur cluster binding
CSPUT_RS02355	COG3301	Polysulphide reductase, NrfD
CSPUT_RS02365	COG5002	protein histidine kinase activity
CSPUT_RS02380	COG0277	FAD linked oxidase domain protein
CSPUT_RS02385	COG0052	Belongs to the universal ribosomal protein uS2 family
CSPUT_RS02390	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CSPUT_RS02395	COG1136	(ABC) transporter
CSPUT_RS02400	COG1684	flagellar biosynthetic protein fliR
CSPUT_RS02410	COG0194	GDP metabolic process
CSPUT_RS02415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CSPUT_RS02435	COG2855	membrane
CSPUT_RS02440	COG2863	cytochrome
CSPUT_RS02455	COG2217	Heavy metal translocating P-type atpase
CSPUT_RS02465	COG0126	phosphoglycerate kinase activity
CSPUT_RS02470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSPUT_RS02475	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CSPUT_RS02480	COG0799	negative regulation of ribosome biogenesis
CSPUT_RS02520	COG0305	Participates in initiation and elongation during chromosome replication
CSPUT_RS02540	COG0642	Histidine kinase
CSPUT_RS02545	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CSPUT_RS02550	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CSPUT_RS02560	COG0437	4 iron, 4 sulfur cluster binding
CSPUT_RS02590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CSPUT_RS02595	COG2201	protein-glutamate methylesterase activity
CSPUT_RS02600	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSPUT_RS02620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CSPUT_RS02630	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CSPUT_RS02635	COG0681	Belongs to the peptidase S26 family
CSPUT_RS02640	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CSPUT_RS02650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CSPUT_RS02670	COG5001	Diguanylate cyclase
CSPUT_RS02675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CSPUT_RS02680	COG0298	carbon dioxide binding
CSPUT_RS02685	COG0409	Hydrogenase expression formation protein
CSPUT_RS02690	COG0309	Hydrogenase expression formation protein (HypE)
CSPUT_RS02695	COG0375	protein maturation
CSPUT_RS02700	COG0217	transcriptional regulatory protein
CSPUT_RS02705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CSPUT_RS02710	COG0156	8-amino-7-oxononanoate synthase activity
CSPUT_RS02715	COG2830	Protein of unknown function (DUF452)
CSPUT_RS02720	COG4106	trans-aconitate 2-methyltransferase activity
CSPUT_RS02730	COG0281	malic enzyme
CSPUT_RS02730	COG0280	phosphate acetyltransferase
CSPUT_RS02740	COG0482	sulfurtransferase activity
CSPUT_RS02745	COG1611	Belongs to the LOG family
CSPUT_RS02750	COG1776	CheC inhibitor of MCP methylation
CSPUT_RS02750	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSPUT_RS02755	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSPUT_RS02770	COG0455	bacterial-type flagellum organization
CSPUT_RS02775	COG1419	protein localization to endoplasmic reticulum
CSPUT_RS02780	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CSPUT_RS02785	COG0006	proline dipeptidase activity
CSPUT_RS02790	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CSPUT_RS02805	COG2217	Heavy metal translocating P-type atpase
CSPUT_RS02820	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CSPUT_RS02835	COG1053	succinate dehydrogenase
CSPUT_RS02840	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSPUT_RS02855	COG1012	belongs to the aldehyde dehydrogenase family
CSPUT_RS02860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSPUT_RS02865	COG1218	3'(2'),5'-bisphosphate nucleotidase
CSPUT_RS02870	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CSPUT_RS02875	COG0750	zinc metalloprotease
CSPUT_RS02880	COG0326	Molecular chaperone. Has ATPase activity
CSPUT_RS02890	COG0252	asparaginase activity
CSPUT_RS02895	COG0745	RESPONSE REGULATOR receiver
CSPUT_RS02900	COG0642	Histidine kinase
CSPUT_RS02910	COG0586	Pfam SNARE associated Golgi protein
CSPUT_RS02915	COG0484	heat shock protein binding
CSPUT_RS02920	COG0745	RESPONSE REGULATOR receiver
CSPUT_RS02925	COG0642	Histidine kinase
CSPUT_RS02930	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CSPUT_RS02940	COG1959	2 iron, 2 sulfur cluster binding
CSPUT_RS02945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSPUT_RS02950	COG0840	transmembrane signaling receptor activity
CSPUT_RS02960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CSPUT_RS02965	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CSPUT_RS02970	COG2252	PERMEase
CSPUT_RS03015	COG1555	photosystem II stabilization
CSPUT_RS03015	COG1596	polysaccharide export
CSPUT_RS03090	COG1592	Rubrerythrin
CSPUT_RS03100	COG0166	Belongs to the GPI family
CSPUT_RS03115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSPUT_RS03115	COG1333	cytochrome c biogenesis protein
CSPUT_RS03130	COG1968	undecaprenyl-diphosphatase activity
CSPUT_RS03135	COG0352	thiamine-phosphate diphosphorylase activity
CSPUT_RS03145	COG1126	abc transporter atp-binding protein
CSPUT_RS03150	COG0765	amino acid transport
CSPUT_RS03155	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSPUT_RS03160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CSPUT_RS03165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CSPUT_RS03195	COG0277	FAD linked oxidase domain protein
CSPUT_RS03200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CSPUT_RS03215	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CSPUT_RS03220	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CSPUT_RS03260	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CSPUT_RS03270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSPUT_RS03270	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CSPUT_RS03280	COG0542	response to heat
CSPUT_RS03285	COG0793	Belongs to the peptidase S41A family
CSPUT_RS03290	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CSPUT_RS03295	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSPUT_RS03300	COG0047	phosphoribosylformylglycinamidine synthase activity
CSPUT_RS03310	COG0204	Acyl-transferase
CSPUT_RS03315	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CSPUT_RS03355	COG0534	Mate efflux family protein
CSPUT_RS03360	COG2205	protein histidine kinase activity
CSPUT_RS03370	COG0488	(ABC) transporter
CSPUT_RS03395	COG3022	response to hydroperoxide
CSPUT_RS03400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSPUT_RS03405	COG1674	ftsk spoiiie
CSPUT_RS03405	COG1196	nuclear chromosome segregation
CSPUT_RS03415	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CSPUT_RS03420	COG1151	hydroxylamine reductase activity
CSPUT_RS03430	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CSPUT_RS03445	COG0698	ribose 5-phosphate isomerase
CSPUT_RS03455	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CSPUT_RS03460	COG0586	Pfam SNARE associated Golgi protein
CSPUT_RS03465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CSPUT_RS03480	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CSPUT_RS03485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSPUT_RS03490	COG0191	fructose-bisphosphate aldolase activity
CSPUT_RS03510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CSPUT_RS03560	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CSPUT_RS03575	COG0628	permease
CSPUT_RS03610	COG0275	rRNA processing
CSPUT_RS03620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSPUT_RS03625	COG0849	cell division
CSPUT_RS03630	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CSPUT_RS03640	COG0252	asparaginase activity
CSPUT_RS03645	COG1802	Transcriptional regulator
CSPUT_RS03650	COG1691	(AIR) carboxylase
CSPUT_RS03655	COG1606	tRNA processing
CSPUT_RS03660	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CSPUT_RS03665	COG3875	lactate racemase activity
CSPUT_RS03670	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CSPUT_RS03675	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CSPUT_RS03685	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CSPUT_RS03690	COG1862	Preprotein translocase
CSPUT_RS03695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSPUT_RS03700	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSPUT_RS03710	COG0495	leucyl-tRNA aminoacylation
CSPUT_RS03730	COG0739	heme binding
CSPUT_RS03740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CSPUT_RS03750	COG1692	metallophosphoesterase
CSPUT_RS03765	COG1338	Plays a role in the flagellum-specific transport system
CSPUT_RS03795	COG0640	Transcriptional regulator
CSPUT_RS03810	COG1979	alcohol dehydrogenase
CSPUT_RS03815	COG0181	hydroxymethylbilane synthase activity
CSPUT_RS03830	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CSPUT_RS03835	COG0142	geranyltranstransferase activity
CSPUT_RS03850	COG0546	phosphoglycolate phosphatase activity
CSPUT_RS03870	COG0789	Transcriptional regulator
CSPUT_RS03875	COG0484	heat shock protein binding
CSPUT_RS03880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSPUT_RS03885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CSPUT_RS03895	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CSPUT_RS03900	COG5016	pyruvate
CSPUT_RS03900	COG0511	ligase activity, forming carbon-carbon bonds
CSPUT_RS03905	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CSPUT_RS03910	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CSPUT_RS03920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CSPUT_RS03935	COG0101	tRNA pseudouridine synthase activity
CSPUT_RS04030	COG1555	photosystem II stabilization
CSPUT_RS04030	COG1596	polysaccharide export
CSPUT_RS04045	COG0500	methyltransferase
CSPUT_RS04060	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CSPUT_RS04065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CSPUT_RS04070	COG1663	tetraacyldisaccharide 4'-kinase activity
CSPUT_RS04075	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CSPUT_RS04080	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CSPUT_RS04085	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CSPUT_RS04100	COG0542	response to heat
CSPUT_RS04125	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CSPUT_RS04155	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CSPUT_RS04160	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CSPUT_RS04170	COG0247	lactate metabolic process
CSPUT_RS04175	COG1139	Iron-sulfur cluster binding protein
CSPUT_RS04180	COG1556	Lactate utilization protein
CSPUT_RS04185	COG1620	l-lactate permease
CSPUT_RS04190	COG0488	(ABC) transporter
CSPUT_RS04210	COG3301	Polysulphide reductase, NrfD
CSPUT_RS04220	COG0437	4 iron, 4 sulfur cluster binding
CSPUT_RS04225	COG0243	molybdopterin cofactor binding
CSPUT_RS04265	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CSPUT_RS04270	COG1607	acyl-coa hydrolase
CSPUT_RS04275	COG0071	Belongs to the small heat shock protein (HSP20) family
CSPUT_RS04280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSPUT_RS04285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSPUT_RS04305	COG4591	ABC-type transport system involved in lipoprotein release permease component
CSPUT_RS04315	COG0582	viral genome integration into host DNA
CSPUT_RS04320	COG0772	Belongs to the SEDS family
CSPUT_RS04325	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CSPUT_RS04330	COG0840	transmembrane signaling receptor activity
CSPUT_RS04335	COG1854	S-ribosylhomocysteine lyase activity
CSPUT_RS04340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CSPUT_RS04360	COG0642	Histidine kinase
CSPUT_RS04375	COG0402	S-adenosylhomocysteine deaminase activity
CSPUT_RS04380	COG0110	maltose O-acetyltransferase activity
CSPUT_RS04385	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSPUT_RS04390	COG0438	transferase activity, transferring glycosyl groups
CSPUT_RS04395	COG1287	oligosaccharyl transferase activity
CSPUT_RS04400	COG0438	transferase activity, transferring glycosyl groups
CSPUT_RS04405	COG0438	transferase activity, transferring glycosyl groups
CSPUT_RS04410	COG1442	glycosyl transferase family 8
CSPUT_RS04410	COG1216	Glycosyl transferase, family 2
CSPUT_RS04415	COG0438	transferase activity, transferring glycosyl groups
CSPUT_RS04420	COG3306	glycosyltransferase involved in LPS biosynthesis
CSPUT_RS04425	COG2244	polysaccharide biosynthetic process
CSPUT_RS04440	COG1793	dna ligase
CSPUT_RS04450	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CSPUT_RS04455	COG1560	Kdo2-lipid A biosynthetic process
CSPUT_RS04465	COG0438	transferase activity, transferring glycosyl groups
CSPUT_RS04475	COG0726	polysaccharide deacetylase
CSPUT_RS04480	COG0438	transferase activity, transferring glycosyl groups
CSPUT_RS04495	COG0438	transferase activity, transferring glycosyl groups
CSPUT_RS04505	COG0438	transferase activity, transferring glycosyl groups
CSPUT_RS04515	COG0726	polysaccharide deacetylase
CSPUT_RS04520	COG0463	Glycosyl transferase, family 2
CSPUT_RS04525	COG1748	Saccharopine dehydrogenase
CSPUT_RS04540	COG0489	protein tyrosine kinase activity
CSPUT_RS04545	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CSPUT_RS04550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CSPUT_RS04550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CSPUT_RS04555	COG0745	RESPONSE REGULATOR receiver
CSPUT_RS04560	COG2046	Belongs to the sulfate adenylyltransferase family
CSPUT_RS04625	COG0069	glutamate synthase activity
CSPUT_RS04650	COG1418	mRNA catabolic process
CSPUT_RS04660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSPUT_RS04665	COG0552	protein localization to endoplasmic reticulum
CSPUT_RS04670	COG1114	Component of the transport system for branched-chain amino acids
CSPUT_RS04680	COG0840	transmembrane signaling receptor activity
CSPUT_RS04685	COG0840	transmembrane signaling receptor activity
CSPUT_RS04690	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CSPUT_RS04695	COG0445	tRNA wobble uridine modification
CSPUT_RS04720	COG0501	Belongs to the peptidase M48B family
CSPUT_RS04725	COG0733	neurotransmitter:sodium symporter activity
CSPUT_RS04730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CSPUT_RS04735	COG0137	argininosuccinate synthase activity
CSPUT_RS04740	COG0359	binds to the 23S rRNA
CSPUT_RS04745	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CSPUT_RS04750	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CSPUT_RS04755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CSPUT_RS04785	COG1459	type II secretion system
CSPUT_RS04795	COG1496	oxidoreductase activity
CSPUT_RS04800	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CSPUT_RS04805	COG1959	2 iron, 2 sulfur cluster binding
CSPUT_RS04810	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSPUT_RS04815	COG2404	hydrolase activity, acting on ester bonds
CSPUT_RS04945	COG3210	domain, Protein
CSPUT_RS04950	COG2831	hemolysin activation secretion protein
CSPUT_RS04965	COG0612	Peptidase, M16
CSPUT_RS04980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSPUT_RS04995	COG1193	negative regulation of DNA recombination
CSPUT_RS05005	COG2200	EAL domain
CSPUT_RS05005	COG2199	diguanylate cyclase activity
CSPUT_RS05005	COG3287	FIST C domain
CSPUT_RS05010	COG1280	lysine exporter protein (LysE YggA)
CSPUT_RS05015	COG0251	oxidation-reduction process
CSPUT_RS05050	COG1755	Isoprenylcysteine carboxyl methyltransferase
CSPUT_RS05095	COG0519	Catalyzes the synthesis of GMP from XMP
CSPUT_RS05120	COG1546	Belongs to the CinA family
CSPUT_RS05120	COG1058	Belongs to the CinA family
CSPUT_RS05130	COG2861	carbohydrate metabolic process
CSPUT_RS05155	COG0134	indole-3-glycerol-phosphate synthase activity
CSPUT_RS05165	COG0727	PFAM Uncharacterised protein family (UPF0153)
CSPUT_RS05170	COG2813	Specifically methylates the guanine in position
CSPUT_RS05180	COG2072	flavoprotein involved in K transport
CSPUT_RS05185	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CSPUT_RS05205	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CSPUT_RS05230	COG3951	Flagellar rod assembly protein muramidase FlgJ
CSPUT_RS05255	COG1984	allophanate hydrolase subunit 2
CSPUT_RS05260	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CSPUT_RS05265	COG1914	H( )-stimulated, divalent metal cation uptake system
CSPUT_RS05270	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CSPUT_RS05275	COG0390	transport system, permease component
CSPUT_RS05280	COG0398	Pfam SNARE associated Golgi protein
CSPUT_RS05310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSPUT_RS05355	COG1464	Belongs to the NlpA lipoprotein family
CSPUT_RS05365	COG2011	ABC-type metal ion transport system permease component
CSPUT_RS05370	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSPUT_RS05375	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSPUT_RS05385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CSPUT_RS05400	COG0528	UMP kinase activity
CSPUT_RS05415	COG2884	Cell division ATP-binding protein ftsE
CSPUT_RS05420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CSPUT_RS05430	COG0564	pseudouridine synthase activity
CSPUT_RS05435	COG0772	Belongs to the SEDS family
CSPUT_RS05445	COG0243	molybdopterin cofactor binding
CSPUT_RS05460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CSPUT_RS05465	COG0049	tRNA binding
CSPUT_RS05470	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CSPUT_RS05475	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CSPUT_RS05485	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CSPUT_RS05490	COG2957	Belongs to the agmatine deiminase family
CSPUT_RS05495	COG0840	transmembrane signaling receptor activity
CSPUT_RS05500	COG0840	transmembrane signaling receptor activity
CSPUT_RS05505	COG0443	Heat shock 70 kDa protein
CSPUT_RS05510	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CSPUT_RS05515	COG1420	regulation of RNA biosynthetic process
CSPUT_RS05535	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CSPUT_RS05535	COG0674	pyruvate-flavodoxin oxidoreductase activity
CSPUT_RS05545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CSPUT_RS05550	COG0045	succinate-CoA ligase (ADP-forming) activity
CSPUT_RS05560	COG1538	Outer membrane efflux protein
CSPUT_RS05570	COG0588	phosphoglycerate mutase activity
CSPUT_RS05575	COG2833	Protein of unknown function (DUF455)
CSPUT_RS05590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CSPUT_RS05605	COG0163	prenyltransferase activity
CSPUT_RS05610	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CSPUT_RS05615	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CSPUT_RS05620	COG0124	histidyl-tRNA synthetase
CSPUT_RS05625	COG1166	arginine decarboxylase activity
CSPUT_RS05630	COG1045	serine acetyltransferase
CSPUT_RS05645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CSPUT_RS05650	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CSPUT_RS05655	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSPUT_RS05660	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CSPUT_RS05670	COG1301	dicarboxylic acid transport
CSPUT_RS05675	COG1580	Controls the rotational direction of flagella during chemotaxis
CSPUT_RS05680	COG0736	holo-[acyl-carrier-protein] synthase activity
CSPUT_RS05685	COG0728	peptidoglycan biosynthetic process
CSPUT_RS05690	COG0215	cysteine-tRNA ligase activity
CSPUT_RS05695	COG1132	(ABC) transporter
CSPUT_RS05700	COG0167	dihydroorotate dehydrogenase activity
CSPUT_RS05705	COG0612	Peptidase, M16
CSPUT_RS05710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSPUT_RS05715	COG1028	Short-chain dehydrogenase reductase Sdr
CSPUT_RS05720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CSPUT_RS05725	COG1815	bacterial-type flagellum-dependent cell motility
CSPUT_RS05735	COG1677	Flagellar hook-basal body complex protein FliE
CSPUT_RS05740	COG0768	penicillin binding
CSPUT_RS05750	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CSPUT_RS05765	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CSPUT_RS05775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CSPUT_RS05785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CSPUT_RS05790	COG2176	DNA-directed DNA polymerase activity
CSPUT_RS05815	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CSPUT_RS05820	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CSPUT_RS05825	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CSPUT_RS05835	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CSPUT_RS05845	COG0688	phosphatidylethanolamine metabolic process
CSPUT_RS05850	COG1408	metallophosphoesterase
CSPUT_RS05860	COG0440	acetolactate synthase activity
CSPUT_RS05865	COG0028	Belongs to the TPP enzyme family
CSPUT_RS05880	COG0280	phosphate acetyltransferase
CSPUT_RS05885	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CSPUT_RS05890	COG1929	Belongs to the glycerate kinase type-1 family
CSPUT_RS05910	COG0716	FMN binding
CSPUT_RS05920	COG0314	molybdopterin synthase activity
CSPUT_RS05925	COG0303	'Molybdopterin
CSPUT_RS05940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSPUT_RS05940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSPUT_RS05950	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CSPUT_RS05965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSPUT_RS05970	COG1757	Na H antiporter
CSPUT_RS05975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CSPUT_RS05995	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSPUT_RS06015	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CSPUT_RS06020	COG2067	long-chain fatty acid transport protein
CSPUT_RS06025	COG1222	aaa ATPase
CSPUT_RS06030	COG0747	negative chemotaxis
CSPUT_RS06035	COG0601	transmembrane transport
CSPUT_RS06040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSPUT_RS06055	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CSPUT_RS06065	COG1137	ATPase activity
CSPUT_RS06070	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CSPUT_RS06075	COG0484	heat shock protein binding
CSPUT_RS06080	COG2151	metal-sulfur cluster biosynthetic enzyme
CSPUT_RS06105	COG0439	Biotin carboxylase
CSPUT_RS06120	COG0848	biopolymer transport protein
CSPUT_RS06125	COG0811	peptide transport
CSPUT_RS06130	COG4771	TonB-dependent receptor
CSPUT_RS06135	COG4607	ABC-type enterochelin transport system periplasmic component
CSPUT_RS06140	COG4604	ABC transporter, ATP-binding protein
CSPUT_RS06145	COG4605	iron ion homeostasis
CSPUT_RS06150	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSPUT_RS06180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CSPUT_RS06195	COG0564	pseudouridine synthase activity
CSPUT_RS06200	COG1519	Transferase
CSPUT_RS06200	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CSPUT_RS06210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CSPUT_RS06215	COG0752	glycyl-tRNA synthetase alpha subunit
CSPUT_RS06230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CSPUT_RS06235	COG0826	peptidase U32
CSPUT_RS06245	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CSPUT_RS06250	COG0174	glutamine synthetase
CSPUT_RS06255	COG0195	Participates in both transcription termination and antitermination
CSPUT_RS06265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CSPUT_RS06270	COG2121	Domain of unknown function (DUF374)
CSPUT_RS06295	COG0037	tRNA processing
CSPUT_RS06300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CSPUT_RS06305	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CSPUT_RS06310	COG1104	cysteine desulfurase activity
CSPUT_RS06315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CSPUT_RS06315	COG2906	2 iron, 2 sulfur cluster binding
CSPUT_RS06315	COG0822	iron-sulfur transferase activity
CSPUT_RS06350	COG0439	Biotin carboxylase
CSPUT_RS06355	COG0511	ligase activity, forming carbon-carbon bonds
CSPUT_RS06360	COG0717	Belongs to the dCTP deaminase family
CSPUT_RS06365	COG1086	Polysaccharide biosynthesis protein
CSPUT_RS06370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CSPUT_RS06375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CSPUT_RS06385	COG0475	glutathione-regulated potassium exporter activity
CSPUT_RS06385	COG0569	domain protein
CSPUT_RS06390	COG0372	Belongs to the citrate synthase family
CSPUT_RS06405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSPUT_RS06415	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CSPUT_RS06420	COG0113	porphobilinogen synthase activity
CSPUT_RS06425	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CSPUT_RS06445	COG0501	Belongs to the peptidase M48B family
CSPUT_RS06450	COG0668	transmembrane transport
CSPUT_RS06460	COG0776	regulation of translation
CSPUT_RS06465	COG1999	signal sequence binding
CSPUT_RS06480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CSPUT_RS06485	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CSPUT_RS06500	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CSPUT_RS06510	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CSPUT_RS06535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CSPUT_RS06540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CSPUT_RS06545	COG1028	Short-chain dehydrogenase reductase Sdr
CSPUT_RS06550	COG0179	Fumarylacetoacetate (FAA) hydrolase
CSPUT_RS06560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CSPUT_RS06565	COG2860	membrane
CSPUT_RS06570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CSPUT_RS06575	COG1183	phosphatidylcholine synthase activity
CSPUT_RS06580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSPUT_RS06585	COG2264	protein methyltransferase activity
CSPUT_RS06590	COG0745	RESPONSE REGULATOR receiver
CSPUT_RS06595	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CSPUT_RS06600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CSPUT_RS06605	COG1086	Polysaccharide biosynthesis protein
CSPUT_RS06610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CSPUT_RS06625	COG4786	Flagellar basal body rod
CSPUT_RS06630	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CSPUT_RS06635	COG0594	ribonuclease P activity
CSPUT_RS06640	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CSPUT_RS06645	COG0706	membrane insertase activity
CSPUT_RS06655	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CSPUT_RS06660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSPUT_RS06665	COG0484	heat shock protein binding
CSPUT_RS06685	COG0138	bifunctional purine biosynthesis protein purh
CSPUT_RS06710	COG0739	heme binding
CSPUT_RS06715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CSPUT_RS06735	COG0556	nucleotide-excision repair
CSPUT_RS06740	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CSPUT_RS06750	COG0066	3-isopropylmalate dehydratase activity
CSPUT_RS06755	COG0473	3-isopropylmalate dehydrogenase activity
CSPUT_RS06770	COG0617	tRNA 3'-terminal CCA addition
CSPUT_RS06775	COG0788	formyltetrahydrofolate deformylase activity
CSPUT_RS06790	COG0751	glycine-tRNA ligase activity
CSPUT_RS06795	COG0745	RESPONSE REGULATOR receiver
CSPUT_RS06810	COG1053	succinate dehydrogenase
CSPUT_RS06810	COG3976	FMN-binding domain protein
CSPUT_RS06815	COG0469	pyruvate kinase activity
CSPUT_RS06820	COG0579	oxidoreductase
CSPUT_RS06825	COG0471	metal ion transport
CSPUT_RS06835	COG1271	oxidase subunit
CSPUT_RS06855	COG3258	Cytochrome c
CSPUT_RS06875	COG0824	Thioesterase
CSPUT_RS06885	COG1573	uracil-dna glycosylase
CSPUT_RS06890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CSPUT_RS06895	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CSPUT_RS06910	COG0497	DNA recombination
CSPUT_RS06920	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CSPUT_RS06925	COG0563	adenylate kinase activity
CSPUT_RS06930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CSPUT_RS06935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSPUT_RS06955	COG1215	transferase activity, transferring glycosyl groups
CSPUT_RS06965	COG0438	transferase activity, transferring glycosyl groups
CSPUT_RS06985	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CSPUT_RS06990	COG0805	protein transport
CSPUT_RS06995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CSPUT_RS07000	COG0778	Nitroreductase
CSPUT_RS07005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSPUT_RS07015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CSPUT_RS07020	COG0754	glutathionylspermidine amidase activity
CSPUT_RS07025	COG1115	amino acid carrier protein
CSPUT_RS07045	COG0351	phosphomethylpyrimidine kinase
CSPUT_RS07050	COG3839	Belongs to the ABC transporter superfamily
CSPUT_RS07055	COG4662	Binding-protein-dependent transport system inner membrane component
CSPUT_RS07060	COG2998	abc-type tungstate transport system, permease component
CSPUT_RS07065	COG1739	Uncharacterized protein family UPF0029
CSPUT_RS07075	COG1570	exodeoxyribonuclease VII activity
CSPUT_RS07095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CSPUT_RS07105	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSPUT_RS07115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CSPUT_RS07120	COG0077	Prephenate dehydratase
CSPUT_RS07120	COG1605	Chorismate mutase
CSPUT_RS07125	COG0019	diaminopimelate decarboxylase activity
CSPUT_RS07135	COG0193	aminoacyl-tRNA hydrolase activity
CSPUT_RS07160	COG0835	chemotaxis
CSPUT_RS07165	COG0784	Response regulator, receiver
CSPUT_RS07165	COG0643	Histidine kinase
CSPUT_RS07165	COG2198	Histidine kinase
CSPUT_RS07170	COG0835	chemotaxis
CSPUT_RS07170	COG0784	Response regulator, receiver
CSPUT_RS07180	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CSPUT_RS07185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CSPUT_RS07205	COG0716	FMN binding
CSPUT_RS07210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSPUT_RS07215	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSPUT_RS07220	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CSPUT_RS07225	COG0575	Belongs to the CDS family
CSPUT_RS07240	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CSPUT_RS07250	COG1749	Flagellar hook protein flgE
CSPUT_RS07255	COG1760	l-serine dehydratase
CSPUT_RS07260	COG0814	amino acid
CSPUT_RS07270	COG2703	oxygen carrier activity
CSPUT_RS07275	COG0668	transmembrane transport
CSPUT_RS07280	COG0288	reversible hydration of carbon dioxide
CSPUT_RS07285	COG0670	Belongs to the BI1 family
CSPUT_RS07290	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CSPUT_RS07300	COG0233	cytoplasmic translational termination
CSPUT_RS07305	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CSPUT_RS07315	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CSPUT_RS07325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CSPUT_RS07330	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CSPUT_RS07335	COG1047	Peptidyl-prolyl cis-trans
CSPUT_RS07340	COG0492	ferredoxin-NADP+ reductase activity
CSPUT_RS07345	COG3118	belongs to the thioredoxin family
CSPUT_RS07350	COG0792	nuclease activity
CSPUT_RS07355	COG0460	homoserine dehydrogenase
CSPUT_RS07360	COG0436	Aminotransferase
CSPUT_RS07380	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CSPUT_RS07385	COG0254	rRNA binding
CSPUT_RS07390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSPUT_RS07410	COG0602	queuosine metabolic process
CSPUT_RS07415	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CSPUT_RS07470	COG2233	PERMEase
CSPUT_RS07480	COG0105	UTP biosynthetic process
CSPUT_RS07490	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CSPUT_RS07495	COG0416	fatty acid biosynthetic process
CSPUT_RS07500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CSPUT_RS07535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CSPUT_RS07550	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CSPUT_RS07555	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CSPUT_RS07570	COG0561	phosphatase activity
CSPUT_RS07580	COG0741	lytic transglycosylase activity
CSPUT_RS07580	COG1388	LysM domain
CSPUT_RS07585	COG0084	hydrolase, TatD family'
CSPUT_RS07615	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CSPUT_RS07630	COG0733	neurotransmitter:sodium symporter activity
CSPUT_RS07635	COG0733	neurotransmitter:sodium symporter activity
CSPUT_RS07640	COG0733	neurotransmitter:sodium symporter activity
CSPUT_RS07645	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CSPUT_RS07655	COG4773	Receptor
CSPUT_RS07660	COG1555	photosystem II stabilization
CSPUT_RS07660	COG1596	polysaccharide export
CSPUT_RS07690	COG0778	Nitroreductase
CSPUT_RS07700	COG1253	flavin adenine dinucleotide binding
CSPUT_RS07710	COG3260	NADH ubiquinone oxidoreductase 20
CSPUT_RS07720	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CSPUT_RS07720	COG3261	NADH dehydrogenase
CSPUT_RS07725	COG0651	ATP synthesis coupled electron transport
CSPUT_RS07730	COG4237	Hydrogenase 4 membrane
CSPUT_RS07735	COG0650	Formate hydrogenlyase subunit 4
CSPUT_RS07740	COG0651	ATP synthesis coupled electron transport
CSPUT_RS07745	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSPUT_RS07750	COG4783	chaperone-mediated protein folding
CSPUT_RS07755	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CSPUT_RS07760	COG3005	denitrification pathway
CSPUT_RS07765	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CSPUT_RS07770	COG1027	Aspartate ammonia-lyase
CSPUT_RS07775	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CSPUT_RS07785	COG0840	transmembrane signaling receptor activity
CSPUT_RS07790	COG0840	transmembrane signaling receptor activity
CSPUT_RS07800	COG3069	C4-dicarboxylate transmembrane transporter activity
CSPUT_RS07805	COG3340	Belongs to the peptidase S51 family
CSPUT_RS07815	COG0252	asparaginase activity
CSPUT_RS07830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CSPUT_RS07835	COG0540	Belongs to the ATCase OTCase family
CSPUT_RS07840	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CSPUT_RS07850	COG1083	cytidylyl-transferase
CSPUT_RS07860	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CSPUT_RS07870	COG2264	protein methyltransferase activity
CSPUT_RS07900	COG1028	Short-chain dehydrogenase reductase Sdr
CSPUT_RS07940	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CSPUT_RS07970	COG2089	acid synthase
CSPUT_RS07980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CSPUT_RS07985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSPUT_RS07995	COG1213	nucleotidyl transferase
CSPUT_RS08000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CSPUT_RS08005	COG3848	Pyruvate phosphate dikinase
CSPUT_RS08005	COG0574	Belongs to the PEP-utilizing enzyme family
CSPUT_RS08010	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CSPUT_RS08025	COG0529	Catalyzes the synthesis of activated sulfate
CSPUT_RS08040	COG1028	Short-chain dehydrogenase reductase Sdr
CSPUT_RS08050	COG2089	acid synthase
CSPUT_RS08075	COG0243	molybdopterin cofactor binding
CSPUT_RS08085	COG0437	4 iron, 4 sulfur cluster binding
CSPUT_RS08095	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CSPUT_RS08105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CSPUT_RS08120	COG0542	response to heat
CSPUT_RS08130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSPUT_RS08140	COG0481	GTPase activity
CSPUT_RS08145	COG1942	4-Oxalocrotonate Tautomerase
CSPUT_RS08180	COG2204	response regulator
CSPUT_RS08185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSPUT_RS08190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CSPUT_RS08195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSPUT_RS08205	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CSPUT_RS08250	COG1538	Outer membrane efflux protein
CSPUT_RS08255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSPUT_RS08300	COG0714	Associated with various cellular activities
CSPUT_RS08340	COG2207	Transcriptional regulator
CSPUT_RS08340	COG4753	response regulator
CSPUT_RS08345	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CSPUT_RS08350	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CSPUT_RS08360	COG2885	chlorophyll binding
CSPUT_RS08375	COG0848	biopolymer transport protein
CSPUT_RS08380	COG0811	peptide transport
CSPUT_RS08390	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CSPUT_RS08395	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CSPUT_RS08400	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CSPUT_RS08405	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CSPUT_RS08410	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CSPUT_RS08420	COG1475	DNA binding
CSPUT_RS08425	COG1192	Involved in chromosome partitioning
CSPUT_RS08435	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CSPUT_RS08465	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CSPUT_RS08475	COG0840	transmembrane signaling receptor activity
CSPUT_RS08485	COG0437	4 iron, 4 sulfur cluster binding
CSPUT_RS08505	COG1921	L-seryl-tRNASec selenium transferase activity
CSPUT_RS08520	COG1918	ferrous iron import across plasma membrane
CSPUT_RS08595	COG1007	ATP synthesis coupled electron transport
CSPUT_RS08600	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSPUT_RS08605	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSPUT_RS08615	COG0839	Belongs to the complex I subunit 6 family
CSPUT_RS08620	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSPUT_RS08645	COG0649	NAD binding
CSPUT_RS08655	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSPUT_RS08660	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSPUT_RS08665	COG0024	Methionine aminopeptidase
CSPUT_RS08670	COG0201	protein transport
CSPUT_RS08675	COG0200	Binds to the 23S rRNA
CSPUT_RS08680	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CSPUT_RS08685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CSPUT_RS08695	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CSPUT_RS08710	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CSPUT_RS08715	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CSPUT_RS08720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CSPUT_RS08725	COG0255	Belongs to the universal ribosomal protein uL29 family
CSPUT_RS08730	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CSPUT_RS08735	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CSPUT_RS08740	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CSPUT_RS08745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CSPUT_RS08750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CSPUT_RS08755	COG0089	rRNA binding
CSPUT_RS08765	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CSPUT_RS08770	COG0051	transcription antitermination factor activity, RNA binding
CSPUT_RS08785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CSPUT_RS08790	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CSPUT_RS08805	COG0142	geranyltranstransferase activity
CSPUT_RS08810	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CSPUT_RS08815	COG2199	diguanylate cyclase activity
CSPUT_RS08825	COG0243	molybdopterin cofactor binding
CSPUT_RS08830	COG0437	4 iron, 4 sulfur cluster binding
CSPUT_RS08870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CSPUT_RS08875	COG0581	inorganic phosphate transmembrane transporter activity
CSPUT_RS08880	COG0573	inorganic phosphate transmembrane transporter activity
CSPUT_RS08885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CSPUT_RS08900	COG1131	(ABC) transporter
CSPUT_RS08910	COG0848	biopolymer transport protein
CSPUT_RS08915	COG0811	peptide transport
CSPUT_RS08940	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CSPUT_RS08940	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CSPUT_RS08960	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CSPUT_RS08970	COG0564	pseudouridine synthase activity
CSPUT_RS08975	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
