locus-tag	class	description
CSUB8521_RS00010	COG0592	DNA-directed DNA polymerase activity
CSUB8521_RS00015	COG0187	DNA topoisomerase II activity
CSUB8521_RS00030	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CSUB8521_RS00040	COG2824	Alkylphosphonate utilization operon protein PhnA
CSUB8521_RS00050	COG0504	CTP synthase activity
CSUB8521_RS00055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CSUB8521_RS00065	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CSUB8521_RS00070	COG0268	Binds directly to 16S ribosomal RNA
CSUB8521_RS00075	COG1187	pseudouridine synthase activity
CSUB8521_RS00080	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CSUB8521_RS00095	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CSUB8521_RS00100	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CSUB8521_RS00105	COG0564	pseudouridine synthase activity
CSUB8521_RS00110	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CSUB8521_RS00115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSUB8521_RS00120	COG1297	OPT oligopeptide transporter protein
CSUB8521_RS00125	COG1968	undecaprenyl-diphosphatase activity
CSUB8521_RS00130	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CSUB8521_RS00135	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CSUB8521_RS00145	COG2378	regulation of single-species biofilm formation
CSUB8521_RS00205	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CSUB8521_RS00210	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CSUB8521_RS00215	COG1793	dna ligase
CSUB8521_RS00220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSUB8521_RS00245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CSUB8521_RS00255	COG0418	dihydroorotase activity
CSUB8521_RS00270	COG2194	sulfuric ester hydrolase activity
CSUB8521_RS00275	COG0708	Exodeoxyribonuclease III
CSUB8521_RS00290	COG1328	CTP reductase activity
CSUB8521_RS00295	COG0602	queuosine metabolic process
CSUB8521_RS00300	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CSUB8521_RS00305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CSUB8521_RS00315	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CSUB8521_RS00335	COG0051	transcription antitermination factor activity, RNA binding
CSUB8521_RS00340	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CSUB8521_RS00345	COG0088	Forms part of the polypeptide exit tunnel
CSUB8521_RS00350	COG0089	rRNA binding
CSUB8521_RS00355	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CSUB8521_RS00360	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CSUB8521_RS00365	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CSUB8521_RS00370	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CSUB8521_RS00375	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CSUB8521_RS00380	COG0255	Belongs to the universal ribosomal protein uL29 family
CSUB8521_RS00385	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CSUB8521_RS00390	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CSUB8521_RS00395	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CSUB8521_RS00400	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CSUB8521_RS00405	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CSUB8521_RS00410	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CSUB8521_RS00415	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CSUB8521_RS00420	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CSUB8521_RS00425	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CSUB8521_RS00430	COG0200	Binds to the 23S rRNA
CSUB8521_RS00435	COG0201	protein transport
CSUB8521_RS00440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CSUB8521_RS00445	COG0252	asparaginase activity
CSUB8521_RS00450	COG1592	Rubrerythrin
CSUB8521_RS00465	COG0814	amino acid
CSUB8521_RS00470	COG1760	l-serine dehydratase
CSUB8521_RS00475	COG0024	Methionine aminopeptidase
CSUB8521_RS00480	COG0840	transmembrane signaling receptor activity
CSUB8521_RS00485	COG1858	cytochrome C peroxidase
CSUB8521_RS00495	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CSUB8521_RS00500	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CSUB8521_RS00505	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CSUB8521_RS00515	COG0203	ribosomal protein L17
CSUB8521_RS00520	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CSUB8521_RS00530	COG0131	Imidazoleglycerol-phosphate dehydratase
CSUB8521_RS00530	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CSUB8521_RS00560	COG0107	imidazoleglycerol-phosphate synthase activity
CSUB8521_RS00565	COG0140	phosphoribosyl-ATP diphosphatase activity
CSUB8521_RS00565	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CSUB8521_RS00575	COG1749	Flagellar hook protein flgE
CSUB8521_RS00585	COG2814	Major facilitator Superfamily
CSUB8521_RS00590	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CSUB8521_RS00600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CSUB8521_RS00605	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CSUB8521_RS00620	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CSUB8521_RS00625	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CSUB8521_RS00665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CSUB8521_RS00670	COG0642	Histidine kinase
CSUB8521_RS00675	COG0745	RESPONSE REGULATOR receiver
CSUB8521_RS00690	COG1194	a g-specific adenine glycosylase
CSUB8521_RS00730	COG0569	domain protein
CSUB8521_RS00735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSUB8521_RS00745	COG1027	Aspartate ammonia-lyase
CSUB8521_RS00750	COG0840	transmembrane signaling receptor activity
CSUB8521_RS00760	COG2921	Belongs to the UPF0250 family
CSUB8521_RS00765	COG0315	cyclic pyranopterin monophosphate synthase activity
CSUB8521_RS00780	COG2346	COG2346, Truncated hemoglobins
CSUB8521_RS00795	COG0148	phosphopyruvate hydratase activity
CSUB8521_RS00800	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CSUB8521_RS00805	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CSUB8521_RS00810	COG1987	bacterial-type flagellum assembly
CSUB8521_RS00825	COG1218	3'(2'),5'-bisphosphate nucleotidase
CSUB8521_RS00830	COG0475	glutathione-regulated potassium exporter activity
CSUB8521_RS00830	COG0569	domain protein
CSUB8521_RS00835	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CSUB8521_RS00840	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CSUB8521_RS00880	COG2089	acid synthase
CSUB8521_RS00890	COG1776	CheC inhibitor of MCP methylation
CSUB8521_RS00890	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSUB8521_RS00900	COG0248	Ppx GppA phosphatase
CSUB8521_RS00905	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSUB8521_RS00910	COG0745	RESPONSE REGULATOR receiver
CSUB8521_RS00920	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CSUB8521_RS00930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CSUB8521_RS00940	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CSUB8521_RS00950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CSUB8521_RS00955	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CSUB8521_RS00955	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CSUB8521_RS00960	COG1192	Involved in chromosome partitioning
CSUB8521_RS00965	COG1475	DNA binding
CSUB8521_RS00980	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CSUB8521_RS00985	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CSUB8521_RS00990	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CSUB8521_RS00995	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CSUB8521_RS01000	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CSUB8521_RS01005	COG0811	peptide transport
CSUB8521_RS01010	COG0848	biopolymer transport protein
CSUB8521_RS01025	COG2885	chlorophyll binding
CSUB8521_RS01040	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CSUB8521_RS01045	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CSUB8521_RS01050	COG0037	tRNA processing
CSUB8521_RS01070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSUB8521_RS01085	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CSUB8521_RS01090	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CSUB8521_RS01095	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSUB8521_RS01100	COG0287	Prephenate dehydrogenase
CSUB8521_RS01110	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CSUB8521_RS01120	COG0083	homoserine kinase activity
CSUB8521_RS01130	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CSUB8521_RS01140	COG0779	Required for maturation of 30S ribosomal subunits
CSUB8521_RS01150	COG1401	restriction endodeoxyribonuclease activity
CSUB8521_RS01165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSUB8521_RS01165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSUB8521_RS01170	COG0616	signal peptide processing
CSUB8521_RS01175	COG0402	S-adenosylhomocysteine deaminase activity
CSUB8521_RS01180	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CSUB8521_RS01185	COG0006	proline dipeptidase activity
CSUB8521_RS01190	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CSUB8521_RS01195	COG1419	protein localization to endoplasmic reticulum
CSUB8521_RS01200	COG0455	bacterial-type flagellum organization
CSUB8521_RS01210	COG1191	sigma factor activity
CSUB8521_RS01215	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSUB8521_RS01220	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSUB8521_RS01220	COG1776	CheC inhibitor of MCP methylation
CSUB8521_RS01225	COG1611	Belongs to the LOG family
CSUB8521_RS01230	COG0482	sulfurtransferase activity
CSUB8521_RS01235	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CSUB8521_RS01245	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CSUB8521_RS01250	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CSUB8521_RS01255	COG2046	Belongs to the sulfate adenylyltransferase family
CSUB8521_RS01260	COG0745	RESPONSE REGULATOR receiver
CSUB8521_RS01265	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CSUB8521_RS01265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CSUB8521_RS01270	COG0489	protein tyrosine kinase activity
CSUB8521_RS01275	COG2171	N-acyltransferase activity
CSUB8521_RS01285	COG0783	Belongs to the Dps family
CSUB8521_RS01290	COG0166	Belongs to the GPI family
CSUB8521_RS01300	COG1739	Uncharacterized protein family UPF0029
CSUB8521_RS01315	COG0488	(ABC) transporter
CSUB8521_RS01345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSUB8521_RS01360	COG0318	PFAM AMP-dependent synthetase and ligase
CSUB8521_RS01365	COG1028	Short-chain dehydrogenase reductase Sdr
CSUB8521_RS01380	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CSUB8521_RS01400	COG2855	membrane
CSUB8521_RS01415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CSUB8521_RS01430	COG0736	holo-[acyl-carrier-protein] synthase activity
CSUB8521_RS01435	COG1580	Controls the rotational direction of flagella during chemotaxis
CSUB8521_RS01445	COG0753	catalase activity
CSUB8521_RS01455	COG0165	Argininosuccinate lyase
CSUB8521_RS01460	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CSUB8521_RS01470	COG0251	oxidation-reduction process
CSUB8521_RS01475	COG3069	C4-dicarboxylate transmembrane transporter activity
CSUB8521_RS01490	COG2079	MmgE PrpD family protein
CSUB8521_RS01505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CSUB8521_RS01510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CSUB8521_RS01515	COG0825	malonyl-CoA metabolic process
CSUB8521_RS01545	COG0517	IMP dehydrogenase activity
CSUB8521_RS01545	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CSUB8521_RS01590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSUB8521_RS01595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSUB8521_RS01600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSUB8521_RS01615	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CSUB8521_RS01650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSUB8521_RS01695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CSUB8521_RS01700	COG0574	Belongs to the PEP-utilizing enzyme family
CSUB8521_RS01700	COG3848	Pyruvate phosphate dikinase
CSUB8521_RS01705	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CSUB8521_RS01710	COG1213	nucleotidyl transferase
CSUB8521_RS01715	COG0529	Catalyzes the synthesis of activated sulfate
CSUB8521_RS01750	COG0195	Participates in both transcription termination and antitermination
CSUB8521_RS01765	COG2121	Domain of unknown function (DUF374)
CSUB8521_RS01790	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CSUB8521_RS01800	COG1053	succinate dehydrogenase
CSUB8521_RS01805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSUB8521_RS01835	COG1064	alcohol dehydrogenase
CSUB8521_RS01840	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CSUB8521_RS01860	COG3177	Filamentation induced by cAMP protein fic
CSUB8521_RS01870	COG0303	'Molybdopterin
CSUB8521_RS01875	COG0314	molybdopterin synthase activity
CSUB8521_RS01900	COG2986	histidine ammonia-lyase
CSUB8521_RS01905	COG3976	FMN-binding domain protein
CSUB8521_RS01905	COG1053	succinate dehydrogenase
CSUB8521_RS01930	COG0243	molybdopterin cofactor binding
CSUB8521_RS01935	COG3383	formate dehydrogenase (NAD+) activity
CSUB8521_RS01940	COG0437	4 iron, 4 sulfur cluster binding
CSUB8521_RS01950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSUB8521_RS01950	COG0425	Belongs to the sulfur carrier protein TusA family
CSUB8521_RS01955	COG0709	Synthesizes selenophosphate from selenide and ATP
CSUB8521_RS01965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSUB8521_RS01970	COG0425	Belongs to the sulfur carrier protein TusA family
CSUB8521_RS01985	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CSUB8521_RS02005	COG0505	Belongs to the CarA family
CSUB8521_RS02055	COG1074	ATP-dependent DNA helicase activity
CSUB8521_RS02060	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CSUB8521_RS02065	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CSUB8521_RS02075	COG0546	phosphoglycolate phosphatase activity
CSUB8521_RS02080	COG1013	pyruvate-flavodoxin oxidoreductase activity
CSUB8521_RS02080	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CSUB8521_RS02080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSUB8521_RS02080	COG0674	pyruvate-flavodoxin oxidoreductase activity
CSUB8521_RS02100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CSUB8521_RS02105	COG1459	type II secretion system
CSUB8521_RS02135	COG3951	Flagellar rod assembly protein muramidase FlgJ
CSUB8521_RS02140	COG1706	bacterial-type flagellum-dependent cell motility
CSUB8521_RS02165	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CSUB8521_RS02185	COG0716	FMN binding
CSUB8521_RS02215	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CSUB8521_RS02225	COG0126	phosphoglycerate kinase activity
CSUB8521_RS02230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSUB8521_RS02265	COG0114	fumarate hydratase activity
CSUB8521_RS02270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CSUB8521_RS02280	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CSUB8521_RS02285	COG2252	PERMEase
CSUB8521_RS02295	COG0243	molybdopterin cofactor binding
CSUB8521_RS02315	COG4773	Receptor
CSUB8521_RS02320	COG3022	response to hydroperoxide
CSUB8521_RS02345	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CSUB8521_RS02350	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CSUB8521_RS02365	COG0250	Participates in transcription elongation, termination and antitermination
CSUB8521_RS02370	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CSUB8521_RS02375	COG0081	regulation of translation
CSUB8521_RS02380	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CSUB8521_RS02385	COG0222	ribosome binding
CSUB8521_RS02390	COG0085	RNA polymerase activity
CSUB8521_RS02395	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CSUB8521_RS02400	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CSUB8521_RS02405	COG0049	tRNA binding
CSUB8521_RS02410	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CSUB8521_RS02415	COG1253	flavin adenine dinucleotide binding
CSUB8521_RS02420	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CSUB8521_RS02425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSUB8521_RS02495	COG0848	biopolymer transport protein
CSUB8521_RS02500	COG0811	peptide transport
CSUB8521_RS02505	COG4771	TonB-dependent receptor
CSUB8521_RS02510	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CSUB8521_RS02515	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CSUB8521_RS02520	COG2217	Heavy metal translocating P-type atpase
CSUB8521_RS02535	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CSUB8521_RS02540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSUB8521_RS02545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CSUB8521_RS02545	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CSUB8521_RS02550	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CSUB8521_RS02555	COG0469	pyruvate kinase activity
CSUB8521_RS02560	COG0579	oxidoreductase
CSUB8521_RS02565	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CSUB8521_RS02585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSUB8521_RS02605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CSUB8521_RS02620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CSUB8521_RS02625	COG0484	heat shock protein binding
CSUB8521_RS02630	COG0745	RESPONSE REGULATOR receiver
CSUB8521_RS02635	COG0642	Histidine kinase
CSUB8521_RS02640	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CSUB8521_RS02670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CSUB8521_RS02670	COG0519	Catalyzes the synthesis of GMP from XMP
CSUB8521_RS02675	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CSUB8521_RS02695	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CSUB8521_RS02705	COG1185	polyribonucleotide nucleotidyltransferase activity
CSUB8521_RS02750	COG2226	methyltransferase
CSUB8521_RS02785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSUB8521_RS02795	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CSUB8521_RS02800	COG0653	protein targeting
CSUB8521_RS02805	COG2204	response regulator
CSUB8521_RS02810	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSUB8521_RS02820	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CSUB8521_RS02825	COG0731	radical SAM domain protein
CSUB8521_RS02835	COG3063	Type IV pilus biogenesis stability protein PilW
CSUB8521_RS02840	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CSUB8521_RS02850	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CSUB8521_RS02855	COG1160	GTP binding
CSUB8521_RS02865	COG2233	PERMEase
CSUB8521_RS02875	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CSUB8521_RS02880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CSUB8521_RS02885	COG0284	orotidine-5'-phosphate decarboxylase activity
CSUB8521_RS02895	COG0840	transmembrane signaling receptor activity
CSUB8521_RS02900	COG0138	bifunctional purine biosynthesis protein purh
CSUB8521_RS02910	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSUB8521_RS02915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CSUB8521_RS02925	COG0706	membrane insertase activity
CSUB8521_RS02935	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CSUB8521_RS02955	COG0824	Thioesterase
CSUB8521_RS02965	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CSUB8521_RS02980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CSUB8521_RS02985	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSUB8521_RS03005	COG0500	methyltransferase
CSUB8521_RS03020	COG2890	protein-(glutamine-N5) methyltransferase activity
CSUB8521_RS03025	COG0501	Belongs to the peptidase M48B family
CSUB8521_RS03040	COG0488	(ABC) transporter
CSUB8521_RS03045	COG1408	metallophosphoesterase
CSUB8521_RS03050	COG0688	phosphatidylethanolamine metabolic process
CSUB8521_RS03055	COG2257	FlhB HrpN YscU SpaS Family
CSUB8521_RS03080	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CSUB8521_RS03095	COG0681	Belongs to the peptidase S26 family
CSUB8521_RS03105	COG0343	queuine tRNA-ribosyltransferase activity
CSUB8521_RS03115	COG0439	Biotin carboxylase
CSUB8521_RS03135	COG0772	Belongs to the SEDS family
CSUB8521_RS03155	COG0642	Histidine kinase
CSUB8521_RS03170	COG1126	abc transporter atp-binding protein
CSUB8521_RS03175	COG0765	amino acid transport
CSUB8521_RS03180	COG1115	amino acid carrier protein
CSUB8521_RS03190	COG0739	heme binding
CSUB8521_RS03200	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CSUB8521_RS03200	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CSUB8521_RS03220	COG0772	Belongs to the SEDS family
CSUB8521_RS03225	COG0564	pseudouridine synthase activity
CSUB8521_RS03235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CSUB8521_RS03240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSUB8521_RS03255	COG0528	UMP kinase activity
CSUB8521_RS03260	COG1758	RNA polymerase activity
CSUB8521_RS03265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CSUB8521_RS03270	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CSUB8521_RS03310	COG0750	zinc metalloprotease
CSUB8521_RS03315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CSUB8521_RS03320	COG1028	Short-chain dehydrogenase reductase Sdr
CSUB8521_RS03325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSUB8521_RS03330	COG0612	Peptidase, M16
CSUB8521_RS03335	COG0167	dihydroorotate dehydrogenase activity
CSUB8521_RS03340	COG1132	(ABC) transporter
CSUB8521_RS03345	COG0215	cysteine-tRNA ligase activity
CSUB8521_RS03350	COG0728	peptidoglycan biosynthetic process
CSUB8521_RS03360	COG0632	four-way junction helicase activity
CSUB8521_RS03365	COG1181	Belongs to the D-alanine--D-alanine ligase family
CSUB8521_RS03380	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CSUB8521_RS03385	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CSUB8521_RS03390	COG0280	phosphate acetyltransferase
CSUB8521_RS03395	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CSUB8521_RS03400	COG1464	Belongs to the NlpA lipoprotein family
CSUB8521_RS03410	COG2011	ABC-type metal ion transport system permease component
CSUB8521_RS03415	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSUB8521_RS03430	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CSUB8521_RS03435	COG0563	adenylate kinase activity
CSUB8521_RS03445	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CSUB8521_RS03450	COG0497	DNA recombination
CSUB8521_RS03460	COG0084	hydrolase, TatD family'
CSUB8521_RS03465	COG1388	LysM domain
CSUB8521_RS03465	COG0791	NLP P60 protein
CSUB8521_RS03470	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CSUB8521_RS03490	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CSUB8521_RS03510	COG0805	protein transport
CSUB8521_RS03525	COG0640	Transcriptional regulator
CSUB8521_RS03530	COG0748	coenzyme F420 binding
CSUB8521_RS03535	COG4771	TonB-dependent receptor
CSUB8521_RS03540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSUB8521_RS03545	COG1120	ATPase activity
CSUB8521_RS03550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSUB8521_RS03555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSUB8521_RS03560	COG0494	nUDIX hydrolase
CSUB8521_RS03565	COG0527	aspartate kinase activity
CSUB8521_RS03580	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CSUB8521_RS03585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CSUB8521_RS03590	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CSUB8521_RS03595	COG0196	riboflavin kinase activity
CSUB8521_RS03600	COG2890	protein-(glutamine-N5) methyltransferase activity
CSUB8521_RS03615	COG0012	GTP binding
CSUB8521_RS03620	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CSUB8521_RS03640	COG0698	ribose 5-phosphate isomerase
CSUB8521_RS03645	COG2201	protein-glutamate methylesterase activity
CSUB8521_RS03650	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CSUB8521_RS03660	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CSUB8521_RS03665	COG0612	Peptidase, M16
CSUB8521_RS03670	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CSUB8521_RS03675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSUB8521_RS03680	COG0765	amino acid transport
CSUB8521_RS03685	COG0765	amino acid transport
CSUB8521_RS03695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSUB8521_RS03720	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CSUB8521_RS03730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CSUB8521_RS03740	COG0521	Mo-molybdopterin cofactor biosynthetic process
CSUB8521_RS03750	COG0326	Molecular chaperone. Has ATPase activity
CSUB8521_RS03755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CSUB8521_RS03760	COG0204	Acyl-transferase
CSUB8521_RS03770	COG0047	phosphoribosylformylglycinamidine synthase activity
CSUB8521_RS03775	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSUB8521_RS03780	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CSUB8521_RS03785	COG0793	Belongs to the peptidase S41A family
CSUB8521_RS03790	COG0542	response to heat
CSUB8521_RS03795	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CSUB8521_RS03800	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CSUB8521_RS03805	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CSUB8521_RS03810	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CSUB8521_RS03820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CSUB8521_RS03840	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CSUB8521_RS03850	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSUB8521_RS03850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSUB8521_RS03870	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CSUB8521_RS03905	COG1794	racemase activity, acting on amino acids and derivatives
CSUB8521_RS03910	COG0582	viral genome integration into host DNA
CSUB8521_RS03915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CSUB8521_RS03945	COG0163	prenyltransferase activity
CSUB8521_RS03950	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CSUB8521_RS03955	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CSUB8521_RS03960	COG0124	histidyl-tRNA synthetase
CSUB8521_RS03965	COG1166	arginine decarboxylase activity
CSUB8521_RS03980	COG1045	serine acetyltransferase
CSUB8521_RS03990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CSUB8521_RS03995	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CSUB8521_RS04000	COG1137	ATPase activity
CSUB8521_RS04005	COG0802	atpase or kinase
CSUB8521_RS04010	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CSUB8521_RS04015	COG0137	argininosuccinate synthase activity
CSUB8521_RS04020	COG0359	binds to the 23S rRNA
CSUB8521_RS04025	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CSUB8521_RS04035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CSUB8521_RS04075	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CSUB8521_RS04080	COG0181	hydroxymethylbilane synthase activity
CSUB8521_RS04090	COG0442	prolyl-tRNA aminoacylation
CSUB8521_RS04095	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CSUB8521_RS04100	COG0142	geranyltranstransferase activity
CSUB8521_RS04130	COG0789	Transcriptional regulator
CSUB8521_RS04135	COG0484	heat shock protein binding
CSUB8521_RS04140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSUB8521_RS04145	COG0745	RESPONSE REGULATOR receiver
CSUB8521_RS04150	COG0642	Histidine kinase
CSUB8521_RS04155	COG0210	DNA helicase
CSUB8521_RS04160	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CSUB8521_RS04170	COG0375	protein maturation
CSUB8521_RS04175	COG0309	Hydrogenase expression formation protein (HypE)
CSUB8521_RS04180	COG0409	Hydrogenase expression formation protein
CSUB8521_RS04185	COG0298	carbon dioxide binding
CSUB8521_RS04195	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CSUB8521_RS04200	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CSUB8521_RS04210	COG0534	Mate efflux family protein
CSUB8521_RS04265	COG0581	inorganic phosphate transmembrane transporter activity
CSUB8521_RS04270	COG0573	inorganic phosphate transmembrane transporter activity
CSUB8521_RS04275	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CSUB8521_RS04285	COG2205	protein histidine kinase activity
CSUB8521_RS04295	COG1528	Iron-storage protein
CSUB8521_RS04305	COG0484	heat shock protein binding
CSUB8521_RS04320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSUB8521_RS04320	COG1333	cytochrome c biogenesis protein
CSUB8521_RS04330	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSUB8521_RS04335	COG0440	acetolactate synthase activity
CSUB8521_RS04340	COG0028	Belongs to the TPP enzyme family
CSUB8521_RS04350	COG1013	pyruvate-flavodoxin oxidoreductase activity
CSUB8521_RS04355	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CSUB8521_RS04355	COG0674	pyruvate-flavodoxin oxidoreductase activity
CSUB8521_RS04365	COG0039	L-malate dehydrogenase activity
CSUB8521_RS04380	COG1674	ftsk spoiiie
CSUB8521_RS04380	COG1196	nuclear chromosome segregation
CSUB8521_RS04385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSUB8521_RS04635	COG3501	Rhs element vgr protein
CSUB8521_RS05265	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CSUB8521_RS05275	COG0587	DNA-directed DNA polymerase activity
CSUB8521_RS05280	COG0693	protein deglycase activity
CSUB8521_RS05290	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CSUB8521_RS05300	COG3258	Cytochrome c
CSUB8521_RS05315	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CSUB8521_RS05325	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CSUB8521_RS05330	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CSUB8521_RS05335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSUB8521_RS05340	COG0765	amino acid transport
CSUB8521_RS05355	COG1252	NADH dehydrogenase
CSUB8521_RS05360	COG0733	neurotransmitter:sodium symporter activity
CSUB8521_RS05370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSUB8521_RS05375	COG1116	anion transmembrane transporter activity
CSUB8521_RS05400	COG0191	fructose-bisphosphate aldolase activity
CSUB8521_RS05405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSUB8521_RS05410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CSUB8521_RS05415	COG0786	glutamate:sodium symporter activity
CSUB8521_RS05425	COG0577	efflux transmembrane transporter activity
CSUB8521_RS05425	COG1136	(ABC) transporter
CSUB8521_RS05430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSUB8521_RS05435	COG0778	Nitroreductase
CSUB8521_RS05465	COG0727	PFAM Uncharacterised protein family (UPF0153)
CSUB8521_RS05475	COG0134	indole-3-glycerol-phosphate synthase activity
CSUB8521_RS05485	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CSUB8521_RS05500	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CSUB8521_RS05520	COG0443	Heat shock 70 kDa protein
CSUB8521_RS05525	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CSUB8521_RS05545	COG2404	hydrolase activity, acting on ester bonds
CSUB8521_RS05550	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSUB8521_RS05555	COG1959	2 iron, 2 sulfur cluster binding
CSUB8521_RS05560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CSUB8521_RS05565	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CSUB8521_RS05565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CSUB8521_RS05570	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CSUB8521_RS05585	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CSUB8521_RS05590	COG0557	exoribonuclease II activity
CSUB8521_RS05600	COG0360	Binds together with S18 to 16S ribosomal RNA
CSUB8521_RS05605	COG0629	single-stranded DNA binding
CSUB8521_RS05610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CSUB8521_RS05615	COG2095	MarC family integral membrane protein
CSUB8521_RS05635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CSUB8521_RS05640	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CSUB8521_RS05650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CSUB8521_RS05670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSUB8521_RS05690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CSUB8521_RS05695	COG1757	Na H antiporter
CSUB8521_RS05700	COG4221	oxidoreductase activity
CSUB8521_RS05705	COG0666	response to abiotic stimulus
CSUB8521_RS05730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CSUB8521_RS05750	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CSUB8521_RS05765	COG1338	Plays a role in the flagellum-specific transport system
CSUB8521_RS05770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSUB8521_RS05785	COG1393	Belongs to the ArsC family
CSUB8521_RS05790	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CSUB8521_RS05800	COG0335	large ribosomal subunit rRNA binding
CSUB8521_RS05815	COG1837	Belongs to the UPF0109 family
CSUB8521_RS05820	COG0228	four-way junction DNA binding
CSUB8521_RS05825	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CSUB8521_RS05830	COG0564	pseudouridine synthase activity
CSUB8521_RS05835	COG1519	Transferase
CSUB8521_RS05845	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CSUB8521_RS05850	COG0752	glycyl-tRNA synthetase alpha subunit
CSUB8521_RS05860	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CSUB8521_RS05865	COG0826	peptidase U32
CSUB8521_RS05875	COG0174	glutamine synthetase
CSUB8521_RS05880	COG0788	formyltetrahydrofolate deformylase activity
CSUB8521_RS05885	COG0617	tRNA 3'-terminal CCA addition
CSUB8521_RS05900	COG2807	transmembrane transport
CSUB8521_RS05915	COG3043	anaerobic respiration
CSUB8521_RS05920	COG0348	domain, Protein
CSUB8521_RS05925	COG0437	4 iron, 4 sulfur cluster binding
CSUB8521_RS05930	COG0243	molybdopterin cofactor binding
CSUB8521_RS05940	COG4786	Flagellar basal body rod
CSUB8521_RS05945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CSUB8521_RS05950	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CSUB8521_RS05960	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CSUB8521_RS05975	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CSUB8521_RS05980	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CSUB8521_RS05995	COG0840	transmembrane signaling receptor activity
CSUB8521_RS06005	COG0459	protein refolding
CSUB8521_RS06010	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CSUB8521_RS06030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CSUB8521_RS06040	COG0739	heme binding
CSUB8521_RS06045	COG0285	dihydrofolate synthase activity
CSUB8521_RS06060	COG0495	leucyl-tRNA aminoacylation
CSUB8521_RS06070	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSUB8521_RS06075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSUB8521_RS06080	COG1862	Preprotein translocase
CSUB8521_RS06085	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CSUB8521_RS06090	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CSUB8521_RS06095	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CSUB8521_RS06100	COG0540	Belongs to the ATCase OTCase family
CSUB8521_RS06115	COG0210	DNA helicase
CSUB8521_RS06135	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CSUB8521_RS06150	COG0542	response to heat
CSUB8521_RS06155	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CSUB8521_RS06160	COG1815	bacterial-type flagellum-dependent cell motility
CSUB8521_RS06165	COG1558	bacterial-type flagellum-dependent cell motility
CSUB8521_RS06170	COG1677	Flagellar hook-basal body complex protein FliE
CSUB8521_RS06180	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CSUB8521_RS06185	COG0673	inositol 2-dehydrogenase activity
CSUB8521_RS06195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CSUB8521_RS06200	COG0424	maF-like protein
CSUB8521_RS06210	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CSUB8521_RS06230	COG2217	Heavy metal translocating P-type atpase
CSUB8521_RS06245	COG0217	transcriptional regulatory protein
CSUB8521_RS06250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CSUB8521_RS06260	COG0586	Pfam SNARE associated Golgi protein
CSUB8521_RS06270	COG3610	response to peptide
CSUB8521_RS06275	COG0018	arginyl-trna synthetase
CSUB8521_RS06280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CSUB8521_RS06285	COG0194	GDP metabolic process
CSUB8521_RS06295	COG1684	flagellar biosynthetic protein fliR
CSUB8521_RS06300	COG1136	(ABC) transporter
CSUB8521_RS06305	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CSUB8521_RS06310	COG0052	Belongs to the universal ribosomal protein uS2 family
CSUB8521_RS06320	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CSUB8521_RS06325	COG0723	plastoquinol--plastocyanin reductase activity
CSUB8521_RS06340	COG1496	oxidoreductase activity
CSUB8521_RS06350	COG0642	Histidine kinase
CSUB8521_RS06360	COG2703	oxygen carrier activity
CSUB8521_RS06365	COG2703	oxygen carrier activity
CSUB8521_RS06375	COG4773	Receptor
CSUB8521_RS06385	COG0683	leucine binding
CSUB8521_RS06415	COG1333	cytochrome c biogenesis protein
CSUB8521_RS06415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSUB8521_RS06425	COG0481	GTPase activity
CSUB8521_RS06445	COG0352	thiamine-phosphate diphosphorylase activity
CSUB8521_RS06450	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CSUB8521_RS06455	COG0351	phosphomethylpyrimidine kinase
CSUB8521_RS06460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CSUB8521_RS06475	COG0357	Ribosomal RNA small subunit methyltransferase G
CSUB8521_RS06480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CSUB8521_RS06485	COG0113	porphobilinogen synthase activity
CSUB8521_RS06495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSUB8521_RS06500	COG0247	lactate metabolic process
CSUB8521_RS06500	COG2181	nitrate reductase activity
CSUB8521_RS06510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CSUB8521_RS06530	COG1999	signal sequence binding
CSUB8521_RS06535	COG4591	ABC-type transport system involved in lipoprotein release permease component
CSUB8521_RS06550	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CSUB8521_RS06565	COG0471	metal ion transport
CSUB8521_RS06575	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CSUB8521_RS06615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CSUB8521_RS06620	COG1280	lysine exporter protein (LysE YggA)
CSUB8521_RS06625	COG3301	Polysulphide reductase, NrfD
CSUB8521_RS06630	COG0437	4 iron, 4 sulfur cluster binding
CSUB8521_RS06635	COG0243	molybdopterin cofactor binding
CSUB8521_RS06645	COG1193	negative regulation of DNA recombination
CSUB8521_RS06675	COG0517	IMP dehydrogenase activity
CSUB8521_RS06675	COG0516	GMP reductase activity
CSUB8521_RS06680	COG0154	amidase activity
CSUB8521_RS06685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CSUB8521_RS06690	COG1058	Belongs to the CinA family
CSUB8521_RS06690	COG1546	Belongs to the CinA family
CSUB8521_RS06720	COG1136	(ABC) transporter
CSUB8521_RS06720	COG0577	efflux transmembrane transporter activity
CSUB8521_RS06745	COG0672	)-iron permease
CSUB8521_RS06750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSUB8521_RS06770	COG0275	rRNA processing
CSUB8521_RS06785	COG0849	cell division
CSUB8521_RS06790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CSUB8521_RS06795	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CSUB8521_RS06800	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CSUB8521_RS06810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CSUB8521_RS06860	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CSUB8521_RS06865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSUB8521_RS06875	COG1185	polyribonucleotide nucleotidyltransferase activity
CSUB8521_RS06875	COG0539	negative regulation of cytoplasmic translation
CSUB8521_RS06880	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CSUB8521_RS06885	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CSUB8521_RS06895	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CSUB8521_RS06900	COG0537	adenosine 5'-monophosphoramidase activity
CSUB8521_RS06905	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CSUB8521_RS06915	COG0733	neurotransmitter:sodium symporter activity
CSUB8521_RS06920	COG0733	neurotransmitter:sodium symporter activity
CSUB8521_RS06925	COG0733	neurotransmitter:sodium symporter activity
CSUB8521_RS06930	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CSUB8521_RS06955	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CSUB8521_RS06960	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSUB8521_RS06975	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CSUB8521_RS06985	COG0552	protein localization to endoplasmic reticulum
CSUB8521_RS06990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSUB8521_RS07005	COG0586	Pfam SNARE associated Golgi protein
CSUB8521_RS07015	COG1295	ribonuclease BN
CSUB8521_RS07030	COG0739	heme binding
CSUB8521_RS07035	COG2239	Acts as a magnesium transporter
CSUB8521_RS07040	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CSUB8521_RS07045	COG0305	Participates in initiation and elongation during chromosome replication
CSUB8521_RS07050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSUB8521_RS07055	COG0776	regulation of translation
CSUB8521_RS07065	COG1442	glycosyl transferase family 8
CSUB8521_RS07065	COG1216	Glycosyl transferase, family 2
CSUB8521_RS07075	COG1028	Short-chain dehydrogenase reductase Sdr
CSUB8521_RS07080	COG1083	cytidylyl-transferase
CSUB8521_RS07090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CSUB8521_RS07095	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CSUB8521_RS07100	COG2089	acid synthase
CSUB8521_RS07105	COG2226	methyltransferase
CSUB8521_RS07125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSUB8521_RS07130	COG0110	maltose O-acetyltransferase activity
CSUB8521_RS07150	COG2089	acid synthase
CSUB8521_RS07160	COG0463	Glycosyl transferase, family 2
CSUB8521_RS07165	COG1216	Glycosyl transferase, family 2
CSUB8521_RS07165	COG1442	glycosyl transferase family 8
CSUB8521_RS07175	COG1216	Glycosyl transferase, family 2
CSUB8521_RS07175	COG1442	glycosyl transferase family 8
CSUB8521_RS07190	COG0859	PFAM glycosyl transferase family 9
CSUB8521_RS07200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CSUB8521_RS07205	COG1132	(ABC) transporter
CSUB8521_RS07210	COG0438	transferase activity, transferring glycosyl groups
CSUB8521_RS07215	COG0438	transferase activity, transferring glycosyl groups
CSUB8521_RS07220	COG1287	oligosaccharyl transferase activity
CSUB8521_RS07225	COG0438	transferase activity, transferring glycosyl groups
CSUB8521_RS07230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSUB8521_RS07235	COG0110	maltose O-acetyltransferase activity
CSUB8521_RS07240	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CSUB8521_RS07245	COG1086	Polysaccharide biosynthesis protein
CSUB8521_RS07250	COG0745	RESPONSE REGULATOR receiver
CSUB8521_RS07255	COG2264	protein methyltransferase activity
CSUB8521_RS07260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSUB8521_RS07270	COG1183	phosphatidylcholine synthase activity
CSUB8521_RS07285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CSUB8521_RS07300	COG1607	acyl-coa hydrolase
CSUB8521_RS07305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CSUB8521_RS07310	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CSUB8521_RS07315	COG3421	Type III restriction
CSUB8521_RS07325	COG2255	four-way junction helicase activity
CSUB8521_RS07330	COG0628	permease
CSUB8521_RS07335	COG2814	Major facilitator Superfamily
CSUB8521_RS07340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CSUB8521_RS07385	COG1921	L-seryl-tRNASec selenium transferase activity
CSUB8521_RS07390	COG3276	selenocysteine insertion sequence binding
CSUB8521_RS07405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CSUB8521_RS07410	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CSUB8521_RS07415	COG0281	malic enzyme
CSUB8521_RS07415	COG0280	phosphate acetyltransferase
CSUB8521_RS07420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CSUB8521_RS07430	COG0439	Biotin carboxylase
CSUB8521_RS07435	COG0511	ligase activity, forming carbon-carbon bonds
CSUB8521_RS07440	COG0717	Belongs to the dCTP deaminase family
CSUB8521_RS07445	COG1086	Polysaccharide biosynthesis protein
CSUB8521_RS07450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CSUB8521_RS07455	COG4310	Domain of unknown function (DUF2172)
CSUB8521_RS07490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CSUB8521_RS07505	COG1083	cytidylyl-transferase
CSUB8521_RS07525	COG3980	spore coat polysaccharide biosynthesis protein
CSUB8521_RS07530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSUB8521_RS07545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSUB8521_RS07550	COG0107	imidazoleglycerol-phosphate synthase activity
CSUB8521_RS07565	COG0730	response to heat
CSUB8521_RS07570	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSUB8521_RS07575	COG0840	transmembrane signaling receptor activity
CSUB8521_RS07580	COG0450	alkyl hydroperoxide reductase
CSUB8521_RS07590	COG0105	UTP biosynthetic process
CSUB8521_RS07600	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CSUB8521_RS07605	COG0416	fatty acid biosynthetic process
CSUB8521_RS07610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CSUB8521_RS07615	COG1360	Flagellar Motor Protein
CSUB8521_RS07620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CSUB8521_RS07645	COG0133	tryptophan synthase activity
CSUB8521_RS07660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CSUB8521_RS07665	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CSUB8521_RS07670	COG1570	exodeoxyribonuclease VII activity
CSUB8521_RS07675	COG2226	methyltransferase
CSUB8521_RS07690	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CSUB8521_RS07700	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSUB8521_RS07710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CSUB8521_RS07725	COG0019	diaminopimelate decarboxylase activity
CSUB8521_RS07735	COG0193	aminoacyl-tRNA hydrolase activity
CSUB8521_RS07740	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CSUB8521_RS07745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CSUB8521_RS07755	COG0835	chemotaxis
CSUB8521_RS07760	COG0643	Histidine kinase
CSUB8521_RS07760	COG0784	Response regulator, receiver
CSUB8521_RS07760	COG2198	Histidine kinase
CSUB8521_RS07765	COG0784	Response regulator, receiver
CSUB8521_RS07765	COG0835	chemotaxis
CSUB8521_RS07780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CSUB8521_RS07785	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSUB8521_RS07800	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CSUB8521_RS07805	COG0003	Pfam Anion-transporting ATPase
CSUB8521_RS07815	COG1966	Carbon starvation protein
CSUB8521_RS07825	COG3021	interspecies interaction between organisms
CSUB8521_RS07835	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSUB8521_RS07840	COG3069	C4-dicarboxylate transmembrane transporter activity
CSUB8521_RS07845	COG3340	Belongs to the peptidase S51 family
CSUB8521_RS07850	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CSUB8521_RS07875	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CSUB8521_RS07880	COG4106	trans-aconitate 2-methyltransferase activity
CSUB8521_RS07900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSUB8521_RS07905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CSUB8521_RS07910	COG2076	Multidrug Resistance protein
CSUB8521_RS07915	COG2076	Multidrug Resistance protein
CSUB8521_RS07925	COG1446	asparaginase
CSUB8521_RS07935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CSUB8521_RS07945	COG1077	Cell shape determining protein MreB Mrl
CSUB8521_RS07950	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CSUB8521_RS07955	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSUB8521_RS07960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CSUB8521_RS07965	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CSUB8521_RS07970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CSUB8521_RS07975	COG1942	4-Oxalocrotonate Tautomerase
CSUB8521_RS07985	COG0330	HflC and HflK could
CSUB8521_RS08000	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CSUB8521_RS08005	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CSUB8521_RS08015	COG0492	ferredoxin-NADP+ reductase activity
CSUB8521_RS08020	COG3118	belongs to the thioredoxin family
CSUB8521_RS08025	COG0792	nuclease activity
CSUB8521_RS08030	COG0460	homoserine dehydrogenase
CSUB8521_RS08035	COG0436	Aminotransferase
CSUB8521_RS08055	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CSUB8521_RS08060	COG0254	rRNA binding
CSUB8521_RS08065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSUB8521_RS08085	COG0602	queuosine metabolic process
CSUB8521_RS08090	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CSUB8521_RS08110	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CSUB8521_RS08120	COG1007	ATP synthesis coupled electron transport
CSUB8521_RS08125	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSUB8521_RS08130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSUB8521_RS08140	COG0839	Belongs to the complex I subunit 6 family
CSUB8521_RS08150	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CSUB8521_RS08175	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSUB8521_RS08180	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSUB8521_RS08185	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSUB8521_RS08190	COG4608	Belongs to the ABC transporter superfamily
CSUB8521_RS08200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSUB8521_RS08215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSUB8521_RS08225	COG1139	Iron-sulfur cluster binding protein
CSUB8521_RS08230	COG0247	lactate metabolic process
CSUB8521_RS08250	COG2890	protein-(glutamine-N5) methyltransferase activity
CSUB8521_RS08260	COG0243	molybdopterin cofactor binding
CSUB8521_RS08350	COG0582	viral genome integration into host DNA
CSUB8521_RS08380	COG0861	Integral membrane protein TerC family
CSUB8521_RS08385	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CSUB8521_RS08390	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CSUB8521_RS08390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CSUB8521_RS08405	COG0606	chelatase, subunit chli
CSUB8521_RS08410	COG0242	peptide deformylase activity
CSUB8521_RS08420	COG0740	serine-type endopeptidase activity
CSUB8521_RS08425	COG0544	peptidyl-prolyl cis-trans isomerase activity
CSUB8521_RS08430	COG0302	gtp cyclohydrolase
CSUB8521_RS08435	COG1157	protein secretion by the type III secretion system
CSUB8521_RS08465	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CSUB8521_RS08485	COG2860	membrane
CSUB8521_RS08495	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CSUB8521_RS08505	COG0328	RNA-DNA hybrid ribonuclease activity
CSUB8521_RS08515	COG0358	DNA primase activity
CSUB8521_RS08525	COG0840	transmembrane signaling receptor activity
CSUB8521_RS08530	COG4953	penicillin-binding protein 1C
CSUB8521_RS08535	COG2373	Large extracellular alpha-helical protein
CSUB8521_RS08550	COG0668	transmembrane transport
CSUB8521_RS08555	COG0288	reversible hydration of carbon dioxide
CSUB8521_RS08560	COG0670	Belongs to the BI1 family
CSUB8521_RS08565	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CSUB8521_RS08570	COG0233	cytoplasmic translational termination
CSUB8521_RS08575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CSUB8521_RS08585	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSUB8521_RS08600	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CSUB8521_RS08615	COG1217	gtp-binding protein TYPA
CSUB8521_RS08635	COG1749	Flagellar hook protein flgE
CSUB8521_RS08650	COG2184	nucleotidyltransferase activity
CSUB8521_RS08655	COG3842	ATPase activity
CSUB8521_RS08660	COG1176	ABC-type spermidine putrescine transport system, permease component I
CSUB8521_RS08665	COG1840	ABC-type Fe3 transport system, periplasmic component
CSUB8521_RS08670	COG0243	molybdopterin cofactor binding
CSUB8521_RS08675	COG0437	4 iron, 4 sulfur cluster binding
CSUB8521_RS08700	COG4615	Cyclic peptide transporter
CSUB8521_RS08735	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CSUB8521_RS08740	COG0575	Belongs to the CDS family
CSUB8521_RS08760	COG2056	Na+-H+ antiporter family
CSUB8521_RS08765	COG0129	dihydroxy-acid dehydratase activity
CSUB8521_RS08790	COG0840	transmembrane signaling receptor activity
CSUB8521_RS08795	COG0840	transmembrane signaling receptor activity
CSUB8521_RS08805	COG1222	aaa ATPase
CSUB8521_RS08815	COG1666	GTP binding
CSUB8521_RS08820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CSUB8521_RS08825	COG0754	glutathionylspermidine amidase activity
CSUB8521_RS08840	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CSUB8521_RS08850	COG1309	transcriptional regulator
CSUB8521_RS08875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSUB8521_RS08880	COG1981	membrane
CSUB8521_RS08890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSUB8521_RS08900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CSUB8521_RS08900	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CSUB8521_RS08940	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CSUB8521_RS08950	COG0741	lytic transglycosylase activity
CSUB8521_RS08955	COG2833	Protein of unknown function (DUF455)
CSUB8521_RS08985	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CSUB8521_RS09050	COG1122	ATPase activity
CSUB8521_RS09065	COG2194	sulfuric ester hydrolase activity
CSUB8521_RS09075	COG1843	Required for flagellar hook formation. May act as a scaffolding protein