locus-tag	class	description
AB162_RS00015	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AB162_RS00015	COG0047	phosphoribosylformylglycinamidine synthase activity
AB162_RS00025	COG0483	inositol monophosphate 1-phosphatase activity
AB162_RS00035	COG0105	UTP biosynthetic process
AB162_RS00040	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AB162_RS00045	COG0124	histidyl-tRNA synthetase
AB162_RS00050	COG1160	GTP binding
AB162_RS00070	COG1322	Protein conserved in bacteria
AB162_RS00085	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AB162_RS00090	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AB162_RS00095	COG2937	Belongs to the GPAT DAPAT family
AB162_RS00100	COG0180	Tryptophanyl-tRNA synthetase
AB162_RS00120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB162_RS00125	COG0586	Pfam SNARE associated Golgi protein
AB162_RS00130	COG5007	Belongs to the BolA IbaG family
AB162_RS00140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB162_RS00160	COG0151	Belongs to the GarS family
AB162_RS00170	COG0511	ligase activity, forming carbon-carbon bonds
AB162_RS00175	COG0439	Biotin carboxylase
AB162_RS00190	COG0306	phosphate transporter
AB162_RS00195	COG0425	Belongs to the sulfur carrier protein TusA family
AB162_RS00200	COG0552	protein localization to endoplasmic reticulum
AB162_RS00210	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AB162_RS00220	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AB162_RS00240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB162_RS00275	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AB162_RS00280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AB162_RS00285	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AB162_RS00295	COG2878	Part of a membrane complex involved in electron transport
AB162_RS00300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AB162_RS00305	COG1846	Transcriptional regulator
AB162_RS00315	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AB162_RS00320	COG0307	riboflavin synthase, alpha
AB162_RS00350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB162_RS00355	COG0716	FMN binding
AB162_RS00365	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AB162_RS00380	COG2885	chlorophyll binding
AB162_RS00385	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AB162_RS00390	COG0037	tRNA processing
AB162_RS00395	COG0025	NhaP-type Na H and K H
AB162_RS00400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AB162_RS00405	COG1121	(ABC) transporter
AB162_RS00410	COG0629	single-stranded DNA binding
AB162_RS00415	COG1301	dicarboxylic acid transport
AB162_RS00420	COG1846	Transcriptional regulator
AB162_RS00425	COG0194	GDP metabolic process
AB162_RS00430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AB162_RS00435	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AB162_RS00440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB162_RS00440	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB162_RS00445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AB162_RS00450	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AB162_RS00460	COG0563	adenylate kinase activity
AB162_RS00465	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AB162_RS00470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AB162_RS00495	COG1011	Hydrolase
AB162_RS00500	COG0210	DNA helicase
AB162_RS00505	COG0598	Magnesium transport protein CorA
AB162_RS00515	COG0187	DNA topoisomerase II activity
AB162_RS00525	COG0592	DNA-directed DNA polymerase activity
AB162_RS00530	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AB162_RS00535	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AB162_RS00550	COG0706	membrane insertase activity
AB162_RS00575	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AB162_RS00590	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AB162_RS00615	COG0354	folic acid binding
AB162_RS00620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AB162_RS00625	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AB162_RS00630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AB162_RS00635	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AB162_RS00680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AB162_RS00690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AB162_RS00705	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AB162_RS00715	COG0205	6-phosphofructokinase activity
AB162_RS00725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AB162_RS00730	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AB162_RS00740	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AB162_RS00745	COG1561	YicC-like family, N-terminal region
AB162_RS00750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AB162_RS00755	COG0756	dUTP diphosphatase activity
AB162_RS00790	COG3118	belongs to the thioredoxin family
AB162_RS00805	COG0542	response to heat
AB162_RS00815	COG0336	Belongs to the RNA methyltransferase TrmD family
AB162_RS00850	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AB162_RS00855	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AB162_RS00870	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AB162_RS00880	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AB162_RS00895	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AB162_RS00900	COG0316	Belongs to the HesB IscA family
AB162_RS00905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB162_RS00910	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AB162_RS00915	COG0617	tRNA 3'-terminal CCA addition
AB162_RS00920	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AB162_RS00930	COG1466	dna polymerase III delta subunit
AB162_RS00940	COG0321	lipoyl(octanoyl) transferase activity
AB162_RS00950	COG0477	Major facilitator Superfamily
AB162_RS00955	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AB162_RS00975	COG2706	6-phosphogluconolactonase activity
AB162_RS00980	COG0588	phosphoglycerate mutase activity
AB162_RS00985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AB162_RS00990	COG0539	negative regulation of cytoplasmic translation
AB162_RS00995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AB162_RS01020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AB162_RS01030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AB162_RS01035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AB162_RS01040	COG1845	cytochrome c oxidase, subunit III
AB162_RS01045	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AB162_RS01050	COG0109	protoheme IX farnesyltransferase activity
AB162_RS01055	COG2814	Major facilitator Superfamily
AB162_RS01060	COG0142	geranyltranstransferase activity
AB162_RS01065	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AB162_RS01085	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AB162_RS01090	COG0571	ribonuclease III activity
AB162_RS01115	COG2927	DNA polymerase III (CHI subunit)
AB162_RS01120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AB162_RS01125	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AB162_RS01130	COG2890	protein-(glutamine-N5) methyltransferase activity
AB162_RS01160	COG0012	GTP binding
AB162_RS01165	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AB162_RS01190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB162_RS01195	COG2916	Histone family protein nucleoid-structuring protein H-NS
AB162_RS01200	COG0501	Belongs to the peptidase M48B family
AB162_RS01205	COG1528	Iron-storage protein
AB162_RS01210	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AB162_RS01215	COG0469	pyruvate kinase activity
AB162_RS01220	COG1914	H( )-stimulated, divalent metal cation uptake system
AB162_RS01260	COG3107	peptidoglycan biosynthetic process
AB162_RS01260	COG1674	ftsk spoiiie
AB162_RS01260	COG1674	ftsk spoiiie
AB162_RS01260	COG3107	peptidoglycan biosynthetic process
AB162_RS01265	COG0492	ferredoxin-NADP+ reductase activity
AB162_RS01275	COG1126	abc transporter atp-binding protein
AB162_RS01280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB162_RS01285	COG4215	(ABC) transporter
AB162_RS01300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AB162_RS01310	COG0089	rRNA binding
AB162_RS01325	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AB162_RS01330	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AB162_RS01350	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AB162_RS01355	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AB162_RS01360	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AB162_RS01370	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AB162_RS01395	COG0200	Binds to the 23S rRNA
AB162_RS01400	COG0201	protein transport
AB162_RS01405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AB162_RS01430	COG0203	ribosomal protein L17
AB162_RS01460	COG2062	phosphohistidine phosphatase, SixA
AB162_RS01465	COG2890	protein-(glutamine-N5) methyltransferase activity
AB162_RS01470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AB162_RS01475	COG0101	tRNA pseudouridine synthase activity
AB162_RS01485	COG0285	dihydrofolate synthase activity
AB162_RS01490	COG1286	toxin biosynthetic process
AB162_RS01495	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AB162_RS01500	COG0163	prenyltransferase activity
AB162_RS01505	COG1007	ATP synthesis coupled electron transport
AB162_RS01510	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB162_RS01515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AB162_RS01520	COG0713	ATP synthesis coupled electron transport
AB162_RS01525	COG0839	Belongs to the complex I subunit 6 family
AB162_RS01530	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB162_RS01535	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AB162_RS01545	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AB162_RS01575	COG0280	phosphate acetyltransferase
AB162_RS01575	COG0857	belongs to the CobB CobQ family
AB162_RS01580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AB162_RS01590	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB162_RS01595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AB162_RS01620	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AB162_RS01625	COG0791	NLP P60 protein
AB162_RS01635	COG0833	amino acid
AB162_RS01645	COG0717	Belongs to the dCTP deaminase family
AB162_RS01655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AB162_RS01660	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AB162_RS01660	COG0140	phosphoribosyl-ATP diphosphatase activity
AB162_RS01675	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AB162_RS01680	COG0131	Imidazoleglycerol-phosphate dehydratase
AB162_RS01680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AB162_RS01690	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AB162_RS01720	COG1067	ATP-dependent peptidase activity
AB162_RS01730	COG2920	part of a sulfur-relay system
AB162_RS01755	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AB162_RS01755	COG1013	pyruvate-flavodoxin oxidoreductase activity
AB162_RS01755	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB162_RS01755	COG0674	pyruvate-flavodoxin oxidoreductase activity
AB162_RS01775	COG2915	High frequency lysogenization protein hflD homolog
AB162_RS01780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AB162_RS01785	COG4591	ABC-type transport system involved in lipoprotein release permease component
AB162_RS01790	COG1136	(ABC) transporter
AB162_RS01795	COG4591	ABC-type transport system involved in lipoprotein release permease component
AB162_RS01800	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AB162_RS01805	COG0537	adenosine 5'-monophosphoramidase activity
AB162_RS01810	COG0084	hydrolase, TatD family'
AB162_RS01815	COG0470	DNA polymerase III
AB162_RS01830	COG1028	Short-chain dehydrogenase reductase Sdr
AB162_RS01845	COG0416	fatty acid biosynthetic process
AB162_RS01850	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AB162_RS01860	COG1530	ribonuclease E activity
AB162_RS01865	COG0418	dihydroorotase activity
AB162_RS01870	COG0616	signal peptide processing
AB162_RS01880	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AB162_RS01890	COG2894	cell division
AB162_RS01905	COG3716	PTS system mannose fructose sorbose family IID component
AB162_RS01910	COG3715	PTS system
AB162_RS01915	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB162_RS01915	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB162_RS01920	COG1253	flavin adenine dinucleotide binding
AB162_RS01925	COG1054	Belongs to the UPF0176 family
AB162_RS01950	COG2814	Major facilitator Superfamily
AB162_RS01955	COG1566	PFAM secretion protein HlyD family protein
AB162_RS01960	COG2166	iron-sulfur cluster assembly
AB162_RS01965	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AB162_RS01970	COG0719	Fe-S assembly protein
AB162_RS01975	COG0396	ATPase activity
AB162_RS01980	COG0719	Fe-S assembly protein
AB162_RS01985	COG0316	Belongs to the HesB IscA family
AB162_RS01990	COG0072	phenylalanine-tRNA ligase activity
AB162_RS01990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB162_RS02010	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AB162_RS02035	COG3021	interspecies interaction between organisms
AB162_RS02040	COG0741	lytic transglycosylase activity
AB162_RS02045	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AB162_RS02050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AB162_RS02055	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AB162_RS02060	COG0189	ligase activity
AB162_RS02070	COG0316	Belongs to the HesB IscA family
AB162_RS02070	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AB162_RS02085	COG0735	belongs to the Fur family
AB162_RS02090	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AB162_RS02095	COG2923	Belongs to the DsrF TusC family
AB162_RS02100	COG2168	tRNA wobble position uridine thiolation
AB162_RS02130	COG0250	Participates in transcription elongation, termination and antitermination
AB162_RS02135	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AB162_RS02155	COG0085	RNA polymerase activity
AB162_RS02190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB162_RS02195	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB162_RS02200	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AB162_RS02205	COG0157	Belongs to the NadC ModD family
AB162_RS02210	COG0237	dephospho-CoA kinase activity
AB162_RS02215	COG0653	protein targeting
AB162_RS02230	COG0849	cell division
AB162_RS02235	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AB162_RS02240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AB162_RS02250	COG0772	Belongs to the SEDS family
AB162_RS02260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AB162_RS02265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AB162_RS02270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AB162_RS02275	COG0768	penicillin binding
AB162_RS02280	COG3116	cell division
AB162_RS02295	COG0052	Belongs to the universal ribosomal protein uS2 family
AB162_RS02320	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AB162_RS02325	COG0575	Belongs to the CDS family
AB162_RS02330	COG0750	zinc metalloprotease
AB162_RS02335	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AB162_RS02340	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AB162_RS02345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AB162_RS02350	COG0587	DNA-directed DNA polymerase activity
AB162_RS02360	COG3066	DNA modification
AB162_RS02365	COG1051	belongs to the nudix hydrolase family
AB162_RS02370	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AB162_RS02380	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AB162_RS02385	COG1074	ATP-dependent DNA helicase activity
AB162_RS02390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AB162_RS02410	COG0443	Heat shock 70 kDa protein
AB162_RS02415	COG0484	heat shock protein binding
AB162_RS02420	COG0268	Binds directly to 16S ribosomal RNA
AB162_RS02425	COG0196	riboflavin kinase activity
AB162_RS02435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AB162_RS02445	COG0505	Belongs to the CarA family
AB162_RS02450	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AB162_RS02455	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AB162_RS02470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB162_RS02480	COG2914	Belongs to the UPF0125 (RnfH) family
AB162_RS02485	COG2867	negative regulation of translational initiation
AB162_RS02500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AB162_RS02505	COG2965	DNA replication, synthesis of RNA primer
AB162_RS02515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB162_RS02520	COG0557	exoribonuclease II activity
AB162_RS02525	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AB162_RS02530	COG0330	HflC and HflK could
AB162_RS02535	COG0330	HflC and HflK could
AB162_RS02540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AB162_RS02560	COG0802	atpase or kinase
AB162_RS02565	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AB162_RS02570	COG0688	phosphatidylethanolamine metabolic process
AB162_RS02575	COG3264	Mechanosensitive ion channel
AB162_RS02575	COG1511	domain protein
AB162_RS02580	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AB162_RS02585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AB162_RS02590	COG1509	lysine 2,3-aminomutase activity
AB162_RS02615	COG0450	alkyl hydroperoxide reductase
AB162_RS02620	COG1862	Preprotein translocase
AB162_RS02625	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AB162_RS02630	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AB162_RS02635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AB162_RS02635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AB162_RS02650	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AB162_RS02655	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AB162_RS02660	COG0442	prolyl-tRNA aminoacylation
AB162_RS02670	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AB162_RS02680	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AB162_RS02695	COG0358	DNA primase activity
AB162_RS02700	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AB162_RS02710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AB162_RS02715	COG1968	undecaprenyl-diphosphatase activity
AB162_RS02740	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AB162_RS02750	COG0513	Belongs to the DEAD box helicase family
AB162_RS02765	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AB162_RS02770	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AB162_RS02780	COG0195	Participates in both transcription termination and antitermination
AB162_RS02805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AB162_RS02815	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AB162_RS02835	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AB162_RS02845	COG0142	geranyltranstransferase activity
AB162_RS02850	COG0126	phosphoglycerate kinase activity
AB162_RS02865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AB162_RS02870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB162_RS02875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB162_RS02885	COG0517	IMP dehydrogenase activity
AB162_RS02885	COG0516	GMP reductase activity