locus_tag old_locus_tag gene Name start end strand product note type ID NCBI AB162_RS00005 AB162_001 AB162_RS00005 1 1548 + malate:quinone oxidoreductase gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00005 AB162_RS00010 AB162_002 AB162_RS00010 1609 2097 + tRNA adenosine deaminase gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00010 AB162_RS00015 AB162_003 AB162_RS00015 2201 6097 + phosphoribosylformylglycinamidine synthase catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00015 AB162_RS00020 AB162_004 AB162_RS00020 6239 7492 + serine hydroxymethyltransferase gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00020 AB162_RS00025 AB162_005 AB162_RS00025 7507 8295 - hypothetical protein gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00025 AB162_RS00030 AB162_006 AB162_RS00030 8410 9583 + cysteine desulfurase catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B involved in NAD biosynthesis gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00030 AB162_RS00035 AB162_007 AB162_RS00035 9670 10104 + nucleoside diphosphate kinase catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00035 AB162_RS00040 AB162_008 AB162_RS00040 10152 11273 + 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00040 AB162_RS00045 AB162_009 hisS hisS 11296 12582 + histidine--tRNA ligase catalyzes a two-step reaction%2C first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B class II aminoacyl-tRNA synthetase%3B forms homodimers%3B some organisms have a paralogous gene%2C hisZ%2C that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00045 AB162_RS00050 AB162_010 AB162_RS00050 12824 14161 + GTP-binding protein Der gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00050 AB162_RS00055 AB162_011 pgi pgi 14348 16015 + glucose-6-phosphate isomerase functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis%3B catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate%3B member of PGI family gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00055 AB162_RS00060 AB162_012 AB162_RS00060 16097 17716 - phosphoenolpyruvate carboxykinase PEP carboxykinase%3B PEP carboxylase%3B PEPCK%3B catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00060 AB162_RS00065 AB162_013 AB162_RS00065 18219 19373 + S-adenosylmethionine synthetase catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B methionine adenosyltransferase gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00065 AB162_RS00070 AB162_014 AB162_RS00070 20098 21516 + recombinase RmuC YigN%3B nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence%3B transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00070 AB162_RS00075 AB162_015 ubiE ubiE 21638 22396 + ubiquinone biosynthesis methyltransferase UbiE Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone and menaquinone gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00075 AB162_RS00080 AB162_016 AB162_RS00080 22417 23007 + hypothetical protein gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00080 AB162_RS00085 AB162_017 ubiB ubiB 23011 24645 + ubiquinone biosynthesis protein UbiB an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone%3B functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis%3B similar to eukaryotic proteins that exhibit kinase functions gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00085 AB162_RS00090 AB162_018 ubiA ubiA 24765 25583 + 4-hydroxybenzoate polyprenyltransferase catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate%2C as part of the ubiquinone biosynthesis pathway gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00090 AB162_RS00095 AB162_019 AB162_RS00095 25598 28060 - glycerol-3-phosphate acyltransferase PlsB%3B catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00095 AB162_RS00100 AB162_020 AB162_RS00100 28196 29209 - tryptophanyl-tRNA synthetase gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00100 AB162_RS00105 AB162_021 AB162_RS00105 29287 29964 - ribulose phosphate epimerase gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00105 AB162_RS00110 AB162_022 aroK aroK 30336 30863 - shikimate kinase type I enzyme similar to type II but differentially regulated%3B major shikimate kinase in fully repressed cells%3B catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00110 AB162_RS00115 AB162_023 AB162_RS00115 30992 31201 + hypothetical protein gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00115 AB162_RS00120 AB162_024 pssA pssA 31241 32608 - phosphatidylserine synthase catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine%3B bounds to the ribosome gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00120 AB162_RS00125 AB162_025 AB162_RS00125 32682 33344 - hypothetical protein gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00125 AB162_RS00130 AB162_026 AB162_RS00130 34428 34676 + cell division protein BolA gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00130 AB162_RS00135 AB162_027 AB162_RS00135 34771 36033 + UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00135 AB162_RS00140 AB162_028 AB162_RS00140 36096 37484 - serine endoprotease DegQ gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00140 AB162_RS00145 AB162_029 AB162_RS00145 38396 38824 + 50S ribosomal protein L13 gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00145 AB162_RS00150 AB162_030 AB162_RS00150 38840 39238 + 30S ribosomal protein S9 gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00150 AB162_RS00155 AB162_031 purH purH 39863 41479 + phosphoribosylaminoimidazolecarboxamide formyltransferase involved in de novo purine biosynthesis gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00155 AB162_RS00160 AB162_032 AB162_RS00160 41504 42793 + phosphoribosylamine--glycine ligase catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00160 AB162_RS00165 AB162_033 AB162_RS00165 42862 43134 - DNA-binding protein gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00165 AB162_RS00170 AB162_035 AB162_RS00170 46078 46518 + acetyl-CoA carboxylase gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00170 AB162_RS00175 AB162_036 AB162_RS00175 46535 47878 + acetyl-CoA carboxylase an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase%2C an enzyme that catalyzes the formation of malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00175 AB162_RS00180 AB162_037 AB162_RS00180 48022 48669 - hypothetical protein gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00180 AB162_RS00185 AB162_038 AB162_RS00185 49069 51123 + oligopeptidase A gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00185 AB162_RS00190 AB162_039 AB162_RS00190 51148 52629 - phosphate transporter PitA involved in the transport of inorganic phosphate gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00190 AB162_RS00195 AB162_040 AB162_RS00195 52881 53138 + hypothetical protein gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00195 AB162_RS00200 AB162_041 AB162_RS00200 53255 54328 + signal recognition particle-docking protein FtsY gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00200 AB162_RS00205 AB162_042 AB162_RS00205 54732 55595 + RNA polymerase factor sigma-32 binds with the catalytic core of RNA polymerase to produce the holoenzyme%3B this sigma factor is responsible for the expression of heat shock promoters gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00205 AB162_RS00210 AB162_043 AB162_RS00210 55658 57127 + 3-octaprenyl-4-hydroxybenzoate carboxy-lyase catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00210 AB162_RS00215 AB162_044 fre fre 57211 57915 + FMN reductase NAD(P)H-flavin reductase%3B catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide%3B in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00215 AB162_RS00220 AB162_045 AB162_RS00220 58633 59118 - rRNA maturation RNase YbeY gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00220 AB162_RS00225 AB162_046 AB162_RS00225 59183 60544 - (dimethylallyl)adenosine tRNA methylthiotransferase catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00225 AB162_RS00230 AB162_047 ubiF ubiF 60638 61818 + 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol hydroxylase catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1%2C4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol%3B functions in the biosynthesis of ubiquinone or coenzyme Q gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00230 AB162_RS00235 AB162_048 ligA ligA 61952 63709 - aromatic ring-opening dioxygenase LigA this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction%3B essential for DNA replication and repair of damaged DNA%3B similar to ligase LigB gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00235 AB162_RS00240 AB162_051 AB162_RS00240 64814 65071 + PTS sugar transporter gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00240 AB162_RS00245 AB162_RS00245 AB162_RS00245 65127 65248 + phosphoenolpyruvate-protein phosphotransferase gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00245 AB162_RS00250 AB162_052 AB162_RS00250 65233 66867 + phosphoenolpyruvate-protein phosphotransferase Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00250 AB162_RS00255 AB162_053 AB162_RS00255 67018 67218 - hypothetical protein gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00255 AB162_RS00260 AB162_RS00260 AB162_RS00260 67205 67417 - hypothetical protein gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00260 AB162_RS00265 AB162_054 AB162_RS00265 67796 68509 - phosphoribosylaminoimidazole-succinocarboxamide synthase catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis%3B SAICAR synthase gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00265 AB162_RS00270 AB162_055 AB162_RS00270 68641 69024 - hypothetical protein gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00270 AB162_RS00275 AB162_056 AB162_RS00275 69302 70348 + phosphoribosylaminoimidazole synthetase catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00275 AB162_RS00280 AB162_057 purN purN 70351 70992 + phosphoribosylglycinamide formyltransferase glycinamide ribonucleotide transformylase%3B GAR Tfase%3B catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate%3B PurN requires formyl folate for the reaction unlike PurT which uses formate gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00280 AB162_RS00285 AB162_058 AB162_RS00285 71294 73291 - transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00285 AB162_RS00290 AB162_059 AB162_RS00290 73307 74260 - transaldolase gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00290 AB162_RS00295 AB162_060 AB162_RS00295 75353 75574 + hypothetical protein gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00295 AB162_RS00300 AB162_061 AB162_RS00300 75621 76895 - tyrosyl-tRNA synthetase gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00300 AB162_RS00305 AB162_062 AB162_RS00305 77506 77937 - transcriptional regulator SlyA Transcription regulator that can both activate or repress expression gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00305 AB162_RS00310 AB162_063 AB162_RS00310 78397 79059 + ribonuclease T Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00310 AB162_RS00315 AB162_064 AB162_RS00315 79076 79414 - glutaredoxin gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00315 AB162_RS00320 AB162_065 AB162_RS00320 79423 80061 - riboflavin synthase subunit alpha catalyzes the formation of riboflavin from 6%2C7-dimethyl-8-(1-D-ribityl)lumazine gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00320 AB162_RS00325 AB162_066 AB162_RS00325 80313 80389 + tRNA-Val tRNA gene64 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00325 AB162_RS00330 AB162_067 AB162_RS00330 80486 80686 + murein lipoprotein major outer membrane lipoprotein%3B interacts with peptidoglycan to maintain the integrity of the cell envelope gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00330 AB162_RS00335 AB162_068 AB162_RS00335 80829 80900 - tRNA-Gln tRNA gene66 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00335 AB162_RS00340 AB162_069 AB162_RS00340 80919 80992 - tRNA-Met tRNA gene67 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00340 AB162_RS00345 AB162_070 AB162_RS00345 81022 81106 - tRNA-Leu tRNA gene68 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00345 AB162_RS00350 AB162_071 AB162_RS00350 81242 82906 + glutamine--tRNA ligase gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00350 AB162_RS00355 AB162_072 AB162_RS00355 82979 83494 - flavodoxin FldA An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00355 AB162_RS00360 AB162_073 AB162_RS00360 83654 85150 + deoxyribodipyrimidine photolyase UV-induced DNA repair%3B converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers%3B light dependent gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00360 AB162_RS00365 AB162_074 AB162_RS00365 85170 85916 + metal-binding protein gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00365 AB162_RS00370 AB162_RS00370 AB162_RS00370 86041 86736 + hypothetical protein gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00370 AB162_RS00375 AB162_RS00375 tolB tolB 88194 89365 + translocation protein TolB forms dimers%3B may be involved in cell envelope integrity%3B interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00375 AB162_RS00380 AB162_079 AB162_RS00380 89400 89951 + peptidoglycan-associated outer membrane lipoprotein gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00380 AB162_RS00385 AB162_081 AB162_RS00385 90284 91312 + quinolinate synthetase 3 different subfamilies%3B catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00385 AB162_RS00390 AB162_082 AB162_RS00390 91351 92769 - hypothetical protein gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00390 AB162_RS00395 AB162_083 AB162_RS00395 92801 94447 - sodium:proton antiporter gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00395 AB162_RS00400 AB162_084 AB162_RS00400 94762 95649 - iron ABC transporter gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00400 AB162_RS00405 AB162_085 AB162_RS00405 95777 96394 - ABC transporter gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00405 AB162_RS00410 AB162_086 AB162_RS00410 96625 97089 - single-stranded DNA-binding protein gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00410 AB162_RS00415 AB162_087 AB162_RS00415 97784 99085 + glutamate:protein symporter gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00415 AB162_RS00420 AB162_088 AB162_RS00420 99657 100082 + MarR family transcriptional regulator gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00420 AB162_RS00425 AB162_089 AB162_RS00425 100285 100920 + guanylate kinase gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00425 AB162_RS00430 AB162_090 AB162_RS00430 101272 103374 + ATP-dependent DNA helicase RecG catalyzes branch migration in Holliday junction intermediates gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00430 AB162_RS00435 AB162_091 AB162_RS00435 103452 104063 + GTP-binding protein gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00435 AB162_RS00440 AB162_092 AB162_RS00440 104101 106863 - DNA polymerase I has 3'-5' exonuclease%2C 5'-3' exonuclease and 5'-3'polymerase activities%2C primarily functions to fill gaps during DNA replication and repair gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00440 AB162_RS00445 AB162_093 AB162_RS00445 107133 108275 + hypothetical protein gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00445 AB162_RS00450 AB162_094 AB162_RS00450 108492 108821 + hypothetical protein gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00450 AB162_RS00455 AB162_095 AB162_RS00455 109071 110996 + heat-shock protein Hsp90 molecular chaperone gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00455 AB162_RS00460 AB162_096 adk adk 111022 111684 + adenylate kinase essential enzyme that recycles AMP in active cells%3B converts ATP and AMP to two molecules of ADP gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00460 AB162_RS00465 AB162_097 AB162_RS00465 111688 112761 - phosphoribosylaminoimidazole carboxylase gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00465 AB162_RS00470 AB162_098 purE purE 112758 113267 - N5-carboxyaminoimidazole ribonucleotide mutase catalyzes the formation of 4-carboxy-5-aminoimidazole ribonucleotide from N5-carboxyaminoimidazole ribonucleotide gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00470 AB162_RS00475 AB162_099 cysS cysS 113395 114831 + cysteine--tRNA ligase catalyzes a two-step reaction%3B charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00475 AB162_RS00480 AB162_100 AB162_RS00480 114858 115718 - methenyltetrahydrofolate cyclohydrolase gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00480 AB162_RS00485 AB162_101 AB162_RS00485 115865 115939 + tRNA-Arg tRNA gene96 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00485 AB162_RS00490 AB162_102 AB162_RS00490 116210 117475 + hypothetical protein gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00490 AB162_RS00495 AB162_104 AB162_RS00495 118548 119264 + flavin mononucleotide phosphatase YigB%3B member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein%3B unknown function gene gene98 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00495 AB162_RS00500 AB162_105 uvrD uvrD 119314 121254 + DNA-dependent helicase II unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present%3B involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. gene gene99 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00500 AB162_RS00505 AB162_106 AB162_RS00505 121446 122396 + magnesium transporter CorA responsible for the influx of magnesium ions gene gene100 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00505 AB162_RS00510 AB162_107 AB162_RS00510 122467 123471 + hypothetical protein gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00510 AB162_RS00515 AB162_108 gyrB gyrB 123521 125920 - DNA gyrase subunit B negatively supercoils closed circular double-stranded DNA gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00515 AB162_RS00520 AB162_109 AB162_RS00520 126278 126772 + hypothetical protein gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00520 AB162_RS00525 AB162_110 AB162_RS00525 126804 127910 - DNA polymerase III subunit beta binds the polymerase to DNA and acts as a sliding clamp gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00525 AB162_RS00530 AB162_111 dnaA dnaA 127932 129233 - chromosomal replication initiation protein binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication%3B can also affect transcription of multiple genes including itself. gene gene105 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00530 AB162_RS00535 AB162_112 rpmH rpmH 129430 129570 + 50S ribosomal protein L34 in Escherichia coli transcription of this gene is enhanced by polyamines gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00535 AB162_RS00540 AB162_113 rnpA rnpA 129593 129943 + ribonuclease P protein component protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus%3B this enzyme also cleaves other RNA substrates gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00540 AB162_RS00545 AB162_114 AB162_RS00545 129919 130176 + hypothetical protein gene gene108 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00545 AB162_RS00550 AB162_115 AB162_RS00550 130179 131792 + insertase functions to insert inner membrane proteins into the IM in Escherichia coli%3B interacts with transmembrane segments%3B functions in both Sec-dependent and -independent membrane insertion%3B similar to Oxa1p in mitochondria gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00550 AB162_RS00555 AB162_116 trmE trmE 131794 133167 + tRNA modification GTPase TrmE in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine%2C which is found in the wobble position of some tRNAs and affects ribosomal frameshifting%3B shows potassium-dependent dimerization and GTP hydrolysis%3B also involved in regulation of glutamate-dependent acid resistance and activation of gadE gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00555 AB162_RS00560 AB162_117 AB162_RS00560 133219 135060 - glucosamine--fructose-6-phosphate aminotransferase Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00560 AB162_RS00565 AB162_118 glmU glmU 135185 136555 - bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase forms a homotrimer%3B catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc%3B function in cell wall synthesis gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00565 AB162_RS00570 AB162_119 atpC atpC 136621 137049 - ATP synthase F0F1 subunit epsilon part of catalytic core of ATP synthase%3B alpha(3)beta(3)gamma(1)delta(1)epsilon(1)%3B involved in producing ATP from ADP in the presence of the proton motive force across the membrane gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00570 AB162_RS00575 AB162_120 AB162_RS00575 137080 138465 - ATP synthase F0F1 subunit beta gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00575 AB162_RS00580 AB162_121 AB162_RS00580 138495 139358 - ATP F0F1 synthase subunit gamma Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00580 AB162_RS00585 AB162_122 AB162_RS00585 139402 140955 - ATP F0F1 synthase subunit alpha produces ATP from ADP in the presence of a proton gradient across the membrane%3B the alpha chain is a catalytic subunit gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00585 AB162_RS00590 AB162_123 AB162_RS00590 140980 141516 - hypothetical protein gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00590 AB162_RS00595 AB162_124 AB162_RS00595 141524 142000 - hypothetical protein gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00595 AB162_RS00600 AB162_125 AB162_RS00600 142021 142260 - ATP F0F1 synthase subunit C Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00600 AB162_RS00605 AB162_126 AB162_RS00605 142294 143139 - ATP synthase F0F1 subunit A Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00605 AB162_RS00610 AB162_127 AB162_RS00610 143213 145111 - hypothetical protein gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00610 AB162_RS00615 AB162_128 AB162_RS00615 145195 146163 - hypothetical protein gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00615 AB162_RS00620 AB162_129 AB162_RS00620 146238 147992 + ssDNA exonuclease RecJ 5'-3' single-stranded-DNA-specific exonuclease gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00620 AB162_RS00625 AB162_130 AB162_RS00625 148088 149182 + peptide chain release factor 2 gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00625 AB162_RS00630 AB162_131 lysS lysS 149189 150721 + lysine--tRNA ligase class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00630 AB162_RS00635 AB162_132 AB162_RS00635 150708 151544 + glutamate racemase converts L-glutamate to D-glutamate%2C a component of peptidoglycan gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00635 AB162_RS00640 AB162_133 AB162_RS00640 151733 153289 + 16S ribosomal RNA rRNA gene127 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00640 AB162_RS00645 AB162_134 AB162_RS00645 153406 153481 + tRNA-Glu tRNA gene128 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00645 AB162_RS00650 AB162_135 AB162_RS00650 153600 156556 + 23S ribosomal RNA rRNA gene129 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00650 AB162_RS00655 AB162_136 AB162_RS00655 156582 156698 + 5S ribosomal RNA rRNA gene130 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00655 AB162_RS00660 AB162_137 AB162_RS00660 156734 156810 + tRNA-Asp tRNA gene131 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00660 AB162_RS00665 AB162_138 AB162_RS00665 156866 156942 + tRNA-Trp tRNA gene132 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00665 AB162_RS00670 AB162_139 glyS glyS 156921 159041 - glycine--tRNA ligase glycine--tRNA ligase beta chain%3B glyS%3B class II aminoacyl tRNA synthetase%3B tetramer of alpha(2)beta(2)%3B catalyzes a two-step reaction%3B first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP%3B second by transfer of the aminoacyl-adenylate to its tRNA gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00670 AB162_RS00675 AB162_140 AB162_RS00675 159038 159967 - glycyl-tRNA synthetase gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00675 AB162_RS00680 AB162_141 AB162_RS00680 160163 161278 + tRNA (uracil-5-)-methyltransferase catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00680 AB162_RS00685 AB162_142 AB162_RS00685 161811 162029 - 50S ribosomal protein L31 gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00685 AB162_RS00690 AB162_143 AB162_RS00690 162132 164333 + primosome assembly protein PriA binding of PriA to forked DNA starts the assembly of the primosome%2C also possesses 3'-5' helicase activity gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00690 AB162_RS00695 AB162_144 AB162_RS00695 164377 164640 + hypothetical protein gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00695 AB162_RS00700 AB162_145 AB162_RS00700 164900 165442 + ATP-dependent protease subunit HslV heat shock protein involved in degradation of misfolded proteins gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00700 AB162_RS00705 AB162_146 hslU hslU 165446 166771 + ATP-dependent protease ATP-binding subunit HslU heat shock protein involved in degradation of misfolded proteins gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00705 AB162_RS00710 AB162_147 AB162_RS00710 167149 167925 + triosephosphate isomerase Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00710 AB162_RS00715 AB162_148 AB162_RS00715 167943 168905 - 6-phosphofructokinase catalyzes the formation of D-fructose 1%2C6-bisphosphate from D-fructose 6-phosphate in glycolysis gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00715 AB162_RS00720 AB162_149 AB162_RS00720 169200 170216 - glycerol-3-phosphate dehydrogenase gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00720 AB162_RS00725 AB162_151 AB162_RS00725 170530 170949 - hypothetical protein gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00725 AB162_RS00730 AB162_153 coaD coaD 171273 171761 + phosphopantetheine adenylyltransferase Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00730 AB162_RS00735 AB162_155 rpmG rpmG 172433 172600 - 50S ribosomal protein L33 in Escherichia coli BM108%2C a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function%3B there are paralogous genes in several bacterial genomes%2C and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31%3B the proteins in this group lack the CXXC motif gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00735 AB162_RS00740 AB162_156 rpmB rpmB 172626 172844 - 50S ribosomal protein L28 required for 70S ribosome assembly gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00740 AB162_RS00745 AB162_157 AB162_RS00745 172926 173798 - hypothetical protein gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00745 AB162_RS00750 AB162_158 pyrE pyrE 173960 174604 + orotate phosphoribosyltransferase involved in fifth step of pyrimidine biosynthesis%3B converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00750 AB162_RS00755 AB162_159 AB162_RS00755 174612 175073 - deoxyuridine 5'-triphosphate nucleotidohydrolase catalyzes the formation of dUMP from dUTP gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00755 AB162_RS00760 AB162_161 AB162_RS00760 175600 175779 + hypothetical protein gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00760 AB162_RS00765 AB162_162 AB162_RS00765 175867 175943 - tRNA-Pro tRNA gene152 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00765 AB162_RS00770 AB162_163 AB162_RS00770 175967 176052 - tRNA-Leu tRNA gene153 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00770 AB162_RS00775 AB162_164 AB162_RS00775 176074 176149 - tRNA-His tRNA gene154 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00775 AB162_RS00780 AB162_165 AB162_RS00780 176222 176299 - tRNA-Arg tRNA gene155 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00780 AB162_RS00785 AB162_166 rho rho 176511 177770 - transcription termination factor Rho An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00785 AB162_RS00790 AB162_167 trxA trxA 177982 178320 - thioredoxin gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00790 AB162_RS00795 AB162_168 AB162_RS00795 178950 179713 - membrane biogenesis protein gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00795 AB162_RS00800 AB162_169 rluD rluD 179805 180776 + 23S rRNA pseudouridylate synthase responsible for synthesis of pseudouridine from uracil at positions 1911%2C 1915 and 1917 in 23S ribosomal RNA gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00800 AB162_RS00805 AB162_170 AB162_RS00805 180850 183432 + Clp protease ClpB gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00805 AB162_RS00810 AB162_171 AB162_RS00810 183435 183812 - 50S ribosomal protein L19 gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00810 AB162_RS00815 AB162_172 trmD trmD 183833 184585 - tRNA (guanine(37)-N(1))-methyltransferase methylates guanosine-37 in various tRNAs%3B uses S-adenosyl-L-methionine to transfer methyl group to tRNA gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00815 AB162_RS00820 AB162_173 rimM rimM 184613 185164 - 16S rRNA-processing protein RimM Essential for efficient processing of 16S rRNA gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00820 AB162_RS00825 AB162_174 rpsP rpsP 185172 185411 - 30S ribosomal protein S16 binds to lower part of 30S body where it stabilizes two domains%3B required for efficient assembly of 30S%3B in Escherichia coli this protein has nuclease activity gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00825 AB162_RS00830 AB162_175 AB162_RS00830 185511 186870 - signal recognition particle gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00830 AB162_RS00835 AB162_176 AB162_RS00835 186896 188476 - glutamate--cysteine ligase involved in the first step of glutathione biosynthesis gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00835 AB162_RS00840 AB162_177 AB162_RS00840 188623 188699 - tRNA-Arg tRNA gene167 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00840 AB162_RS00845 AB162_178 AB162_RS00845 188717 188809 - tRNA-Ser tRNA gene168 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00845 AB162_RS00850 AB162_179 AB162_RS00850 189016 189207 - carbon storage regulator affects carbohydrate metabolism%3B has regulatory role in many processes gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00850 AB162_RS00855 AB162_180 AB162_RS00855 189391 192084 - alanyl-tRNA synthetase gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00855 AB162_RS00860 AB162_181 recA recA 192360 193420 - recombinase A catalyzes the hydrolysis of ATP in the presence of single-stranded DNA%2C the ATP-dependent uptake of single-stranded DNA by duplex DNA%2C and the ATP-dependent hybridization of homologous single-stranded DNAs gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00860 AB162_RS00865 AB162_182 AB162_RS00865 194894 197434 + DNA mismatch repair protein MutS This protein performs the mismatch recognition step during the DNA repair process gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00865 AB162_RS00870 AB162_183 ispF ispF 197773 198249 - 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00870 AB162_RS00875 AB162_184 AB162_RS00875 198261 198989 - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00875 AB162_RS00880 AB162_185 AB162_RS00880 199004 199279 - hypothetical protein gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00880 AB162_RS00885 AB162_186 eno eno 200886 202181 - enolase catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00885 AB162_RS00890 AB162_187 pyrG pyrG 202213 203850 - CTP synthetase CTP synthase%3B cytidine triphosphate synthetase%3B catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B in Escherichia coli this enzyme forms a homotetramer gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00890 AB162_RS00895 AB162_188 AB162_RS00895 204636 205328 + 5'-methylthioadenosine nucleosidase enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00895 AB162_RS00900 AB162_189 AB162_RS00900 205359 205703 - iron-sulfur cluster insertion protein ErpA essential respiratory protein A%3B may be involved in the transfer of iron-sulfur clusters%3B essential for growth using oxygen or alternate electron acceptors gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00900 AB162_RS00905 AB162_190 mrcB mrcB 205839 208301 - bifunctional glycosyl transferase/transpeptidase penicillin-binding protein 1b%3B contains transglycosylase and transpeptidase activity%3B major enzyme for peptidoglycan biosynthesis in Escherichia coli%3B transmembrane protein%3B forms dimers%3B three variants%2C one of which may be a degradation product%2C while the other appears to result from an alternative initiation site%2C are found within the cell gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00905 AB162_RS00910 AB162_191 dksA dksA 208639 209112 + RNA polymerase-binding transcription factor gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00910 AB162_RS00915 AB162_192 pcnB pcnB 209265 210632 + poly(A) polymerase I Polymerase that creates the 3' poly(A) tail found in some mRNA's gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00915 AB162_RS00920 AB162_193 AB162_RS00920 210645 211166 + 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00920 AB162_RS00925 AB162_194 leuS leuS 211234 213840 + leucine--tRNA ligase leucine--tRNA ligase%3B LeuRS%3B class-I aminoacyl-tRNA synthetase%3B charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA%3B due to the large number of codons that tRNA(Leu) recognizes%2C the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA%2C but instead recognition is dependent on a conserved discriminator base A37 and a long arm%3B an editing domain hydrolyzes misformed products%3B in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00925 AB162_RS00930 AB162_195 AB162_RS00930 213954 215015 + hypothetical protein gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00930 AB162_RS00935 AB162_196 AB162_RS00935 215030 215674 + nicotinate-nucleotide adenylyltransferase gene gene186 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00935 AB162_RS00940 AB162_197 AB162_RS00940 215987 216577 + lipoate--protein ligase lipoyl/octanoyltransferase%3B catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00940 AB162_RS00945 AB162_198 AB162_RS00945 216673 217596 + lipoyl synthase catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00945 AB162_RS00950 AB162_199 AB162_RS00950 217883 219109 + multidrug resistance protein MdtH Confers resistance to norfloxacin and enoxacin gene gene189 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00950 AB162_RS00955 AB162_200 AB162_RS00955 219229 219777 + CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene190 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00955 AB162_RS00960 AB162_201 AB162_RS00960 219840 219914 + tRNA-Gly tRNA gene191 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00960 AB162_RS00965 AB162_202 AB162_RS00965 220021 220091 + tRNA-Cys tRNA gene192 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00965 AB162_RS00970 AB162_203 AB162_RS00970 220124 220209 + tRNA-Leu tRNA gene193 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00970 AB162_RS00975 AB162_204 AB162_RS00975 220419 221417 + 6-phosphogluconolactonase catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00975 AB162_RS00980 AB162_205 gpmA gpmA 222091 222789 + phosphoglyceromutase 2%2C3-bisphosphoglycerate-dependent%3B catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00980 AB162_RS00985 AB162_207 AB162_RS00985 223246 223926 + cytidylate kinase gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00985 AB162_RS00990 AB162_208 rpsA rpsA 224053 225744 + 30S ribosomal protein S1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit%3B autoregulates expression via a C-terminal domain%3B in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats%3B the S1 nucleic acid-binding domain is found associated with other proteins gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00990 AB162_RS00995 AB162_210 AB162_RS00995 226049 226684 - protein disulfide isomerase gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS00995 AB162_RS01000 AB162_211 AB162_RS01000 227148 228089 + aspartate carbamoyltransferase catalytic subunit gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01000 AB162_RS01005 AB162_212 AB162_RS01005 228117 228602 + aspartate carbamoyltransferase regulatory subunit involved in the allosteric regulation of aspartate carbamoyltransferase gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01005 AB162_RS01010 AB162_213 AB162_RS01010 228990 229199 - cold-shock protein gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01010 AB162_RS01015 AB162_214 AB162_RS01015 229708 232056 - DNA-binding protein gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01015 AB162_RS01020 AB162_215 clpX clpX 232250 233518 - Clp protease ClpX binds and unfolds substrates as part of the ClpXP protease gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01020 AB162_RS01025 AB162_216 AB162_RS01025 233641 234300 - hypothetical protein gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01025 AB162_RS01030 AB162_217 AB162_RS01030 234737 235633 + cytochrome o ubiquinol oxidase subunit II gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01030 AB162_RS01035 AB162_218 AB162_RS01035 235638 237611 + cytochrome o ubiquinol oxidase subunit I gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01035 AB162_RS01040 AB162_219 AB162_RS01040 237589 238212 + cytochrome o ubiquinol oxidase subunit III gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01040 AB162_RS01045 AB162_RS01045 AB162_RS01045 238212 238532 + hypothetical protein gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01045 AB162_RS01050 AB162_220 AB162_RS01050 238559 239416 + protoheme IX farnesyltransferase converts protoheme IX and farnesyl diphosphate to heme O gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01050 AB162_RS01055 AB162_221 AB162_RS01055 239472 240845 + hypothetical protein gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01055 AB162_RS01060 AB162_222 AB162_RS01060 241382 242275 + geranyl transferase gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01060 AB162_RS01065 AB162_223 AB162_RS01065 242311 244176 + 1-deoxy-D-xylulose-5-phosphate synthase catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01065 AB162_RS01070 AB162_224 AB162_RS01070 244239 245984 + arginyl-tRNA synthetase gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01070 AB162_RS01075 AB162_225 AB162_RS01075 246004 247533 - hypothetical protein gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01075 AB162_RS01080 AB162_226 AB162_RS01080 247624 248004 - hypothetical protein gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01080 AB162_RS01085 AB162_227 AB162_RS01085 248199 249119 - GTPase Era gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01085 AB162_RS01090 AB162_228 rnc rnc 249109 249807 - ribonuclease III cytoplasmic enzyme involved in processing rRNA and some mRNAs%3B substrates typically have dsRNA regions%3B forms a homodimer%3B have N-terminal nuclease and C-terminal RNA-binding domains%3B requires magnesium as preferred ion for activity gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01090 AB162_RS01095 AB162_229 AB162_RS01095 249840 250784 - signal peptidase I catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01095 AB162_RS01100 AB162_230 AB162_RS01100 250828 252624 - elongation factor 4 gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01100 AB162_RS01105 AB162_231 AB162_RS01105 252759 252834 + tRNA-Thr tRNA gene220 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01105 AB162_RS01110 AB162_232 AB162_RS01110 252874 255741 - valine--tRNA ligase gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01110 AB162_RS01115 AB162_233 AB162_RS01115 255773 256216 - DNA polymerase III subunit chi binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01115 AB162_RS01120 AB162_234 AB162_RS01120 256261 257790 - aminopeptidase catalyzes the removal of N-terminal amino acids preferably from various peptides%3B a cyteinylglycinase%2C transcription regulator and site-specific recombination factor gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01120 AB162_RS01125 AB162_235 nadE nadE 257984 258808 + NAD synthetase catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP%3B ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one%3B forms homodimers gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01125 AB162_RS01130 AB162_236 AB162_RS01130 258819 259658 - SAM-dependent methyltransferase HemK%3B PrmC%3B transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01130 AB162_RS01135 AB162_237 prfA prfA 259658 260746 - peptide chain release factor 1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1%3B this protein is similar to release factor 2 gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01135 AB162_RS01140 AB162_238 AB162_RS01140 260943 261566 + outer membrane lipoprotein LolB gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01140 AB162_RS01145 AB162_239 AB162_RS01145 261566 262435 + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01145 AB162_RS01150 AB162_240 AB162_RS01150 262500 263447 + ribose-phosphate pyrophosphokinase catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01150 AB162_RS01155 AB162_241 AB162_RS01155 263511 264089 + peptidyl-tRNA hydrolase Enables the recycling of peptidyl-tRNAs produced at termination of translation gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01155 AB162_RS01160 AB162_242 ychF ychF 264127 265212 + GTP-binding protein EngD%3B translation-associated GTPase%3B the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3)%3B fluorescence spectroscopy revealed nucleic acid binding%3B the yeast protein YBR025c interacts with the translation elongation factor eEF1 gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01160 AB162_RS01165 AB162_243 AB162_RS01165 265261 266040 + enoyl-ACP reductase Catalyzes a key regulatory step in fatty acid biosynthesis gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01165 AB162_RS01170 AB162_244 AB162_RS01170 266128 268070 + exoribonuclease II Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01170 AB162_RS01175 AB162_245 AB162_RS01175 268072 268812 - orotidine 5'-phosphate decarboxylase gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01175 AB162_RS01180 AB162_247 ribA ribA 269506 270093 + GTP cyclohydrolase catalyzes the conversion of GTP to formate and 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01180 AB162_RS01185 AB162_248 AB162_RS01185 270719 273304 - DNA topoisomerase I catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining%2C maintains net negative superhelicity gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01185 AB162_RS01190 AB162_249 cls cls 273819 275279 + cardiolipin synthetase catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01190 AB162_RS01195 AB162_250 AB162_RS01195 275598 276017 + transcriptional regulator gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01195 AB162_RS01200 AB162_251 AB162_RS01200 276204 277082 - heat-shock protein HtpX metalloprotease gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01200 AB162_RS01205 AB162_252 AB162_RS01205 277203 277691 - ferritin cytoplasmic iron storage protein gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01205 AB162_RS01210 AB162_253 AB162_RS01210 277806 279272 - glucose-6-phosphate dehydrogenase catalyzes the formation of D-glucono-1%2C5-lactone 6-phosphate from D-glucose 6-phosphate gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01210 AB162_RS01215 AB162_254 AB162_RS01215 279577 281022 + pyruvate kinase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01215 AB162_RS01220 AB162_256 AB162_RS01220 281307 282662 + manganese transporter gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01220 AB162_RS01225 AB162_257 ruvB ruvB 282714 283724 - ATP-dependent DNA helicase RuvB promotes strand exchange during homologous recombination%3B RuvAB complex promotes branch migration%3B RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences%3B forms hexameric rings around opposite DNA arms%3B requires ATP for branch migration and orientation of RuvAB complex determines direction of migration gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01225 AB162_RS01230 AB162_258 AB162_RS01230 283721 284335 - Holliday junction DNA helicase RuvA gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01230 AB162_RS01235 AB162_259 ruvC ruvC 284436 284924 - Holliday junction resolvase endonuclease%3B resolves Holliday structures%3B forms a complex of RuvABC%3B the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration%3B RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01235 AB162_RS01240 AB162_260 AB162_RS01240 285672 287453 - aspartyl-tRNA synthetase gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01240 AB162_RS01245 AB162_261 AB162_RS01245 287825 288562 - hydrolase gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01245 AB162_RS01250 AB162_262 AB162_RS01250 288658 288747 + tRNA-Ser tRNA gene249 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01250 AB162_RS01255 AB162_263 AB162_RS01255 288797 290089 - seryl-tRNA synthetase gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01255 AB162_RS01260 AB162_265 AB162_RS01260 290802 292655 - hypothetical protein gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01260 AB162_RS01265 AB162_266 AB162_RS01265 292725 293687 + thioredoxin reductase catalyzes the transfer of electrons from NADPH to thioredoxin%3B FAD/NAD(P) binding gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01265 AB162_RS01270 AB162_267 AB162_RS01270 293800 294018 + translation initiation factor IF-1 gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01270 AB162_RS01275 AB162_268 AB162_RS01275 294062 294790 + arginine ABC transporter ATP-binding protein gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01275 AB162_RS01280 AB162_269 AB162_RS01280 294836 295567 + arginine ABC transporter substrate-binding protein gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01280 AB162_RS01285 AB162_270 AB162_RS01285 295573 296253 + arginine transporter permease subunit ArtQ with ArtPMJI transports arginine across the inner membrane gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01285 AB162_RS01290 AB162_271 artM artM 296265 296932 + arginine transporter permease subunit ArtM with ArtPQJI acts to transport arginine across the inner membrane gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01290 AB162_RS01295 AB162_272 rpsJ rpsJ 297382 297693 + 30S ribosomal protein S10 NusE%3B involved in assembly of the 30S subunit%3B in the ribosome%2C this protein is involved in the binding of tRNA%3B in Escherichia coli this protein was also found to be involved in transcription antitermination%3B NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination%3B binding of NusB/S10 to boxA nucleates assembly of the antitermination complex gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01295 AB162_RS01300 AB162_273 AB162_RS01300 297729 298364 + 50S ribosomal protein L3 gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01300 AB162_RS01305 AB162_274 rplD rplD 298375 298986 + 50S ribosomal protein L4 L4 is important during the early stages of 50S assembly%3B it initially binds near the 5' end of the 23S rRNA gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01305 AB162_RS01310 AB162_275 rplW rplW 298983 299288 + 50S ribosomal protein L23 binds third domain of 23S rRNA and protein L29%3B part of exit tunnel gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01310 AB162_RS01315 AB162_276 AB162_RS01315 299308 300129 + 50S ribosomal protein L2 gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01315 AB162_RS01320 AB162_277 AB162_RS01320 300162 300440 + 30S ribosomal protein S19 gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01320 AB162_RS01325 AB162_278 AB162_RS01325 300495 300827 + 50S ribosomal protein L22 gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01325 AB162_RS01330 AB162_279 AB162_RS01330 300844 301545 + 30S ribosomal protein S3 gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01330 AB162_RS01335 AB162_280 AB162_RS01335 301558 301968 + 50S ribosomal protein L16 gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01335 AB162_RS01340 AB162_281 AB162_RS01340 301968 302162 + 50S ribosomal protein L29 one of the stabilizing components for the large ribosomal subunit gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01340 AB162_RS01345 AB162_282 AB162_RS01345 302170 302439 + 30S ribosomal protein S17 gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01345 AB162_RS01350 AB162_283 AB162_RS01350 302459 302830 + 50S ribosomal protein L14 gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01350 AB162_RS01355 AB162_284 AB162_RS01355 302851 303177 + 50S ribosomal protein L24 gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01355 AB162_RS01360 AB162_285 AB162_RS01360 303192 303731 + 50S ribosomal protein L5 gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01360 AB162_RS01365 AB162_286 rpsN rpsN 303759 304064 + 30S ribosomal protein S14 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit%3B similar to what is observed with proteins L31 and L33%2C some proteins in this family contain CXXC motifs that are involved in zinc binding%3B if two copies are present in a genome%2C then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc%3B the proteins in this group do not appear to have the zinc-binding motif gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01365 AB162_RS01370 AB162_287 AB162_RS01370 304111 304503 + 30S ribosomal protein S8 gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01370 AB162_RS01375 AB162_288 AB162_RS01375 304533 305066 + 50S ribosomal protein L6 gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01375 AB162_RS01380 AB162_290 AB162_RS01380 305076 305435 + 50S ribosomal protein L18 gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01380 AB162_RS01385 AB162_291 AB162_RS01385 305445 305945 + 30S ribosomal protein S5 gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01385 AB162_RS01390 AB162_292 rpmD rpmD 305953 306132 + 50S ribosomal protein L30 L30 binds domain II of the 23S rRNA and the 5S rRNA%3B similar to eukaryotic protein L7 gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01390 AB162_RS01395 AB162_293 AB162_RS01395 306144 306578 + 50S ribosomal protein L15 gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01395 AB162_RS01400 AB162_294 secY secY 306590 307921 + preprotein translocase subunit SecY forms heterotrimeric complex in the membrane%3B in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG%3B the SecG subunit is not essential%3B in bacteria translocation is driven via the SecA ATPase gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01400 AB162_RS01405 AB162_295 AB162_RS01405 307934 308050 + 50S ribosomal protein L36 gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01405 AB162_RS01410 AB162_296 AB162_RS01410 308156 308512 + 30S ribosomal protein S13 gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01410 AB162_RS01415 AB162_297 AB162_RS01415 308533 308922 + 30S ribosomal protein S11 gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01415 AB162_RS01420 AB162_298 AB162_RS01420 308963 309583 + 30S ribosomal protein S4 gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01420 AB162_RS01425 AB162_299 AB162_RS01425 309614 310606 + DNA-directed RNA polymerase subunit alpha catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01425 AB162_RS01430 AB162_300 rplQ rplQ 310653 311039 + 50S ribosomal protein L17 is a component of the macrolide binding site in the peptidyl transferase center gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01430 AB162_RS01435 AB162_301 AB162_RS01435 311055 311132 - tRNA-Thr tRNA gene286 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01435 AB162_RS01440 AB162_302 AB162_RS01440 311150 311224 - tRNA-Gly tRNA gene287 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01440 AB162_RS01445 AB162_303 AB162_RS01445 311252 311333 - tRNA-Tyr tRNA gene288 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01445 AB162_RS01450 AB162_304 AB162_RS01450 311351 311426 - tRNA-Thr tRNA gene289 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01450 AB162_RS01455 AB162_305 AB162_RS01455 311570 312531 + pantothenate kinase gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01455 AB162_RS01460 AB162_306 AB162_RS01460 312561 312980 + phosphohistidine phosphatase gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01460 AB162_RS01465 AB162_307 AB162_RS01465 313184 314119 + SAM-dependent methyltransferase involved in methylation of ribosomal protein L3 gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01465 AB162_RS01470 AB162_308 AB162_RS01470 314644 315855 + 3-oxoacyl-ACP synthase FabB%2C beta-Ketoacyl-ACP synthase I%2C KASI%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01470 AB162_RS01475 AB162_310 truA truA 316429 317253 + tRNA pseudouridine synthase A mediates pseudouridylation (positions 38%2C 39%2C 40) at the tRNA anticodon region which contributes to the structural stability gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01475 AB162_RS01480 AB162_311 AB162_RS01480 317339 318208 + acetyl-CoA carboxylase subunit beta catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer of AccA2D2 subunits gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01480 AB162_RS01485 AB162_312 AB162_RS01485 318314 319606 + bifunctional folylpolyglutamate synthase/ dihydrofolate synthase gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01485 AB162_RS01490 AB162_314 AB162_RS01490 320199 320657 + colicin V production protein membrane protein required for colicin V production gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01490 AB162_RS01495 AB162_315 AB162_RS01495 320725 322239 + amidophosphoribosyltransferase Catalyzes first step of the de novo purine nucleotide biosynthetic pathway gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01495 AB162_RS01500 AB162_316 AB162_RS01500 322301 322894 + 3-octaprenyl-4-hydroxybenzoate carboxy-lyase catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01500 AB162_RS01505 AB162_317 AB162_RS01505 322941 324398 - NADH:ubiquinone oxidoreductase subunit N Catalyzes the transfer of electrons from NADH to quinone gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01505 AB162_RS01510 AB162_318 AB162_RS01510 324415 325956 - NADH:ubiquinone oxidoreductase subunit M gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01510 AB162_RS01515 AB162_319 AB162_RS01515 326022 327875 - NADH:ubiquinone oxidoreductase subunit L Catalyzes the transfer of electrons from NADH to ubiquinone gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01515 AB162_RS01520 AB162_320 AB162_RS01520 327872 328174 - NADH:ubiquinone oxidoreductase subunit K gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01520 AB162_RS01525 AB162_321 AB162_RS01525 328191 328715 - NADH:ubiquinone oxidoreductase subunit J Catalyzes the transfer of electrons from NADH to quinone gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01525 AB162_RS01530 AB162_322 AB162_RS01530 328743 329285 - NADH dehydrogenase gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01530 AB162_RS01535 AB162_323 AB162_RS01535 329332 330303 - NADH:ubiquinone oxidoreductase gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01535 AB162_RS01540 AB162_324 AB162_RS01540 330300 333038 - NADH dehydrogenase Catalyzes the transfer of electrons from NADH to quinone gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01540 AB162_RS01545 AB162_325 AB162_RS01545 333124 334458 - NADH dehydrogenase part of NADH-ubiquinone oxidoreductase complex I%3B shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B NuoF is part of the soluble NADH dehydrogenase fragment%2C which represents the electron input part of NADH dehydrogenase gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01545 AB162_RS01550 AB162_326 AB162_RS01550 334458 334961 - NADH dehydrogenase Catalyzes the transfer of electrons from NADH to quinone gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01550 AB162_RS01555 AB162_327 AB162_RS01555 334965 336764 - NADH:ubiquinone oxidoreductase NuoCD%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B subunits NuoCD%2C E%2C F%2C and G constitute the peripheral sector of the complex%3B in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01555 AB162_RS01560 AB162_328 AB162_RS01560 336806 337483 - NADH dehydrogenase gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01560 AB162_RS01565 AB162_329 AB162_RS01565 337529 337939 - hypothetical protein gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01565 AB162_RS01570 AB162_330 AB162_RS01570 338159 339370 + acetate kinase AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation%3B utilizes magnesium and ATP%3B also involved in conversion of acetate to aceyl-CoA%3B also known to act on propionate gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01570 AB162_RS01575 AB162_331 AB162_RS01575 339445 341583 + phosphate acetyltransferase catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate%3B when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01575 AB162_RS01580 AB162_332 AB162_RS01580 341635 341886 - 2Fe-2S ferredoxin gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01580 AB162_RS01585 AB162_333 AB162_RS01585 341902 343032 - ribonucleotide-diphosphate reductase subunit beta B2 or R2 protein%3B type 1a enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdA gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01585 AB162_RS01590 AB162_334 AB162_RS01590 343079 345361 - ribonucleotide-diphosphate reductase subunit alpha Catalyzes the rate-limiting step in dNTP synthesis gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01590 AB162_RS01595 AB162_335 AB162_RS01595 345535 346269 - 3-demethylubiquinone-9 3-methyltransferase Involved in ubiquinone biosynthesis gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01595 AB162_RS01600 AB162_336 AB162_RS01600 346450 349026 + DNA gyrase subunit A gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01600 AB162_RS01605 AB162_337 AB162_RS01605 349141 350274 + hypothetical protein gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01605 AB162_RS01610 AB162_338 AB162_RS01610 350330 351430 + D-alanine--D-alanine ligase gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01610 AB162_RS01615 AB162_339 AB162_RS01615 351443 351519 - tRNA-Pro tRNA gene322 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01615 AB162_RS01620 AB162_340 AB162_RS01620 351565 351849 - 50S ribosomal protein L25 the Ctc family of proteins consists of two types%2C one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01620 AB162_RS01625 AB162_341 AB162_RS01625 352053 352619 - hypothetical protein gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01625 AB162_RS01630 AB162_342 AB162_RS01630 352678 353541 - endonuclease IV Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01630 AB162_RS01635 AB162_343 AB162_RS01635 353783 355228 + lysine transporter gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01635 AB162_RS01640 AB162_344 folE folE 355349 356014 + GTP cyclohydrolase involved in the first step of tetrahydrofolate biosynthesis%3B catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1%2C2%2C3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water%3B forms a homopolymer gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01640 AB162_RS01645 AB162_345 AB162_RS01645 356015 356623 - deoxycytidine triphosphate deaminase gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01645 AB162_RS01650 AB162_346 AB162_RS01650 356799 358505 + methionine--tRNA ligase gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01650 AB162_RS01655 AB162_347 AB162_RS01655 358545 359957 - 6-phosphogluconate dehydrogenase catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01655 AB162_RS01660 AB162_348 AB162_RS01660 360153 360764 - phosphoribosyl-ATP pyrophosphatase catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01660 AB162_RS01665 AB162_349 AB162_RS01665 360758 361534 - imidazole glycerol phosphate synthase gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01665 AB162_RS01670 AB162_350 AB162_RS01670 361516 362259 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01670 AB162_RS01675 AB162_351 hisH hisH 362263 362868 - imidazole glycerol phosphate synthase with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate%2C 5-aminoimidazol-4-carboxamide ribonucleotide%2C and glutamate in histidine biosynthesis%3B the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01675 AB162_RS01680 AB162_352 AB162_RS01680 362868 363935 - imidazoleglycerol-phosphate dehydratase catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01680 AB162_RS01685 AB162_353 AB162_RS01685 363958 365019 - histidinol-phosphate aminotransferase catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01685 AB162_RS01690 AB162_354 hisD hisD 365016 366332 - histidinol dehydrogenase catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis%3B functions as a dimer gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01690 AB162_RS01695 AB162_355 hisG hisG 366337 367236 - ATP phosphoribosyltransferase long form of enzyme%3B catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate%3B crucial role in histidine biosynthesis%3B forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01695 AB162_RS01700 AB162_356 AB162_RS01700 368082 368715 + beta-lactamase gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01700 AB162_RS01705 AB162_357 AB162_RS01705 368756 370156 - asparaginyl-tRNA synthetase gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01705 AB162_RS01710 AB162_358 AB162_RS01710 370467 371477 + dihydroorotate dehydrogenase catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway%3B uses a flavin nucleotide as an essential cofactor%3B class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus%2C which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01710 AB162_RS01715 AB162_359 AB162_RS01715 371518 372036 - 3-hydroxydecanoyl-ACP dehydratase catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2%2C3-decenoyl-ACP or 3%2C4-decenoyl-ACP gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01715 AB162_RS01720 AB162_360 AB162_RS01720 372124 373884 - Lon protease gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01720 AB162_RS01725 AB162_361 AB162_RS01725 373963 374280 - heat-shock protein HspQ gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01725 AB162_RS01730 AB162_362 AB162_RS01730 374449 374775 - sulfur relay protein TusE transfers sulfur from TusBCD complex to MnmA%3B involved in thiouridation of U34 position of some tRNAs gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01730 AB162_RS01735 AB162_363 AB162_RS01735 374932 375016 + tRNA-Ser tRNA gene346 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01735 AB162_RS01740 AB162_364 fmt fmt 375053 376006 - methionyl-tRNA formyltransferase modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation%3B inactivation of this gene in Escherichia coli severely impairs growth gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01740 AB162_RS01745 AB162_365 AB162_RS01745 376061 376567 - peptide deformylase gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01745 AB162_RS01750 AB162_366 AB162_RS01750 376740 377294 + tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein involved in the biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01750 AB162_RS01755 AB162_367 AB162_RS01755 377517 381029 - pyruvate-flavodoxin oxidoreductase gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01755 AB162_RS01760 AB162_368 fumC fumC 381121 382518 - fumarate hydratase class II family (does not require metal)%3B tetrameric enzyme%3B fumarase C%3B reversibly converts (S)-malate to fumarate and water%3B functions in the TCA cycle gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01760 AB162_RS01765 AB162_369 AB162_RS01765 382699 382774 + tRNA-Asn tRNA gene352 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01765 AB162_RS01770 AB162_370 mnmA mnmA 382957 384057 + tRNA 2-thiouridylase catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01770 AB162_RS01775 AB162_371 AB162_RS01775 384100 384729 + lysogenization regulator HflD%3B UPF0274%3B in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein%3B in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01775 AB162_RS01780 AB162_372 AB162_RS01780 384771 386147 + adenylosuccinate lyase Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01780 AB162_RS01785 AB162_373 AB162_RS01785 386211 387464 - outer membrane-specific lipoprotein transporter subunit LolE part of the ATP-dependent transport system LolCDE%3B responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01785 AB162_RS01790 AB162_374 lolD lolD 387472 388176 - lipoprotein ABC transporter ATP-binding protein outer membrane specific%3B part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01790 AB162_RS01795 AB162_375 AB162_RS01795 388179 389366 - hypothetical protein gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01795 AB162_RS01800 AB162_376 AB162_RS01800 389432 389959 - hypothetical protein gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01800 AB162_RS01805 AB162_377 AB162_RS01805 390001 390348 - purine nucleoside phosphoramidase gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01805 AB162_RS01810 AB162_378 AB162_RS01810 390404 391210 - DNAse gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01810 AB162_RS01815 AB162_379 AB162_RS01815 391223 392227 - hypothetical protein gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01815 AB162_RS01820 AB162_380 AB162_RS01820 392244 392885 - thymidylate kinase gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01820 AB162_RS01825 AB162_382 AB162_RS01825 393543 393788 - acyl carrier protein carries the fatty acid chain in fatty acid biosynthesis gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01825 AB162_RS01830 AB162_383 fabG fabG 393948 394682 - 3-ketoacyl-ACP reductase catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01830 AB162_RS01835 AB162_384 AB162_RS01835 394679 395629 - malonyl CoA-ACP transacylase gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01835 AB162_RS01840 AB162_385 AB162_RS01840 395644 396600 - 3-oxoacyl-ACP synthase FabH%3B beta-ketoacyl-acyl carrier protein synthase III%3B catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation%3B differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01840 AB162_RS01845 AB162_386 AB162_RS01845 396611 397627 - phosphate acyltransferase gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01845 AB162_RS01850 AB162_387 rpmF rpmF 397654 397824 - 50S ribosomal protein L32 some L32 proteins have zinc finger motifs consisting of CXXC while others do not gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01850 AB162_RS01855 AB162_388 AB162_RS01855 398083 399054 - 23S rRNA pseudouridylate synthase catalyzes the transformation of uracil to pseudouracil at nucleotides U955%2C U2504%2C and U2580 in 23S rRNA gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01855 AB162_RS01860 AB162_389 AB162_RS01860 399528 401348 + ribonuclease E gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01860 AB162_RS01865 AB162_390 AB162_RS01865 401923 402972 + dihydroorotase gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01865 AB162_RS01870 AB162_391 AB162_RS01870 403156 404973 + signal peptide peptidase SppA SppA%3B catalyzes the degradation of cleaved signal peptides%3B essential to maintain secretion of mature proteins across the membrane gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01870 AB162_RS01875 AB162_392 AB162_RS01875 405071 406072 + glyceraldehyde-3-phosphate dehydrogenase gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01875 AB162_RS01880 AB162_393 AB162_RS01880 406156 406698 + hypothetical protein gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01880 AB162_RS01885 AB162_394 minC minC 406740 407432 + septum formation inhibitor blocks the formation of polar Z-ring septums gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01885 AB162_RS01890 AB162_395 AB162_RS01890 407447 408259 + cell division inhibitor MinD ATPase%3B with MinC inhibits cell division by blocking formation of the polar Z ring septums gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01890 AB162_RS01895 AB162_396 minE minE 408263 408547 + cell division topological specificity factor MinE works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01895 AB162_RS01900 AB162_397 AB162_RS01900 408599 409315 - hypothetical protein gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01900 AB162_RS01905 AB162_398 AB162_RS01905 409757 410566 - PTS mannose transporter subunit IID hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IID with IIC forms the translocation channel gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01905 AB162_RS01910 AB162_399 AB162_RS01910 410615 411421 - PTS mannose transporter subunit IIC catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01910 AB162_RS01915 AB162_400 AB162_RS01915 411495 412469 - PTS mannose transporter subunit IIAB catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIA transfers a phosphoryl group to subunit IIB%3B subunit IIB transfers the phosphoryl group to the substrate gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01915 AB162_RS01920 AB162_401 AB162_RS01920 412890 414122 + hypothetical protein gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01920 AB162_RS01925 AB162_402 AB162_RS01925 414716 415675 + sulfurtransferase gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01925 AB162_RS01930 AB162_403 AB162_RS01930 415705 415780 - tRNA-Ala tRNA gene385 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01930 AB162_RS01935 AB162_404 gltX gltX 415845 417254 - glutamine--tRNA ligase catalyzes a two-step reaction%2C first charging an glutamate molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B contains discriminating and non-discriminating subtypes gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01935 AB162_RS01940 AB162_405 AB162_RS01940 417355 417430 + tRNA-Val tRNA gene387 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01940 AB162_RS01945 AB162_406 AB162_RS01945 417472 417547 + tRNA-Lys tRNA gene388 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01945 AB162_RS01950 AB162_407 emrB emrB 417607 419118 - multidrug resistance protein B multidrug MFS transporte%3B with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01950 AB162_RS01955 AB162_408 AB162_RS01955 419131 420306 - hemolysin D gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01955 AB162_RS01960 AB162_409 AB162_RS01960 420388 420852 - cysteine desufuration protein SufE Acts with SufS to catalyze the formation of L-alanine from L-cysteine gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01960 AB162_RS01965 AB162_410 AB162_RS01965 420888 422111 - cysteine sulfinate desulfinase gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01965 AB162_RS01970 AB162_411 AB162_RS01970 422108 423403 - cysteine desulfurase gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01970 AB162_RS01975 AB162_412 sufC sufC 423381 424124 - cysteine desulfurase part of SUF system involved in inserting iron-sulfur clusters into proteins%3B in Escherichia coli this protein forms a complex with SufBD%3B the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01975 AB162_RS01980 AB162_413 AB162_RS01980 424217 425665 - cysteine desulfurase with SufCD activates cysteine desulfurase SufS gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01980 AB162_RS01985 AB162_414 sufA sufA 425703 426077 - iron-sulfur cluster assembly scaffold protein functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]%3B [4Fe-4S]) are assembled%3B forms a homodimer%3B similar to IscA protein gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01985 AB162_RS01990 AB162_415 AB162_RS01990 426097 428472 - phenylalanine--tRNA ligase gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01990 AB162_RS01995 AB162_416 AB162_RS01995 428490 429482 - phenylalanyl-tRNA synthetase gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS01995 AB162_RS02000 AB162_417 rplT rplT 429618 430004 - 50S ribosomal protein L20 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02000 AB162_RS02005 AB162_418 AB162_RS02005 430055 430252 - 50S ribosomal protein L35 gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02005 AB162_RS02010 AB162_419 AB162_RS02010 430300 430842 - translation initiation factor IF-3 gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02010 AB162_RS02015 AB162_420 thrS thrS 430830 432758 - threonine--tRNA ligase catalyzes a two-step reaction%2C first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02015 AB162_RS02020 AB162_421 AB162_RS02020 432986 433702 - DNA polymerase III subunit epsilon 3'-5' exonuclease of DNA polymerase III gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02020 AB162_RS02025 AB162_422 AB162_RS02025 433769 434248 + ribonuclease H gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02025 AB162_RS02030 AB162_423 AB162_RS02030 434245 435009 + hydroxyacylglutathione hydrolase catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione%3B plays an important role in cellular detoxification using glutathione gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02030 AB162_RS02035 AB162_424 AB162_RS02035 435040 435777 - hypothetical protein gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02035 AB162_RS02040 AB162_425 mltC mltC 435881 436930 - murein transglycosylase Murein hydrolase C%3B membrane-bound%3B lytic%3B catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02040 AB162_RS02045 AB162_426 AB162_RS02045 436985 437218 - hypothetical protein gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02045 AB162_RS02050 AB162_427 AB162_RS02050 437298 438428 - coproporphyrinogen III oxidase gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02050 AB162_RS02055 AB162_428 AB162_RS02055 438454 438882 - Holliday junction resolvase similar to RuvC resolvase with substantial differences%3B NMR structural information suggests this protein is monomeric%3B unknown cellular function gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02055 AB162_RS02060 AB162_429 AB162_RS02060 439080 440030 - glutathione synthetase catalyzes the second step in the glutathione biosynthesis pathway%2C where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine %3D ADP + phosphate + glutathione gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02060 AB162_RS02065 AB162_430 AB162_RS02065 440127 440729 - superoxide dismutase SodA%3B manganese binding%3B only present under aerobic conditions%3B destroys free radicals gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02065 AB162_RS02070 AB162_431 AB162_RS02070 440776 441348 - Fe/S biogenesis protein NfuA cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02070 AB162_RS02075 AB162_432 AB162_RS02075 441572 441648 + tRNA-Ile tRNA gene414 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02075 AB162_RS02080 AB162_433 AB162_RS02080 441667 441739 + tRNA-Ala tRNA gene415 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02080 AB162_RS02085 AB162_434 AB162_RS02085 441811 442254 + zinc uptake transcriptional repressor Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02085 AB162_RS02090 AB162_435 AB162_RS02090 442271 442669 + sulfur relay protein TusD in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02090 AB162_RS02095 AB162_436 AB162_RS02095 442687 443049 + sulfur relay protein TusC gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02095 AB162_RS02100 AB162_437 AB162_RS02100 443052 443345 + sulfur relay protein TusB in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02100 AB162_RS02105 AB162_438 AB162_RS02105 443433 443807 + 30S ribosomal protein S12 gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02105 AB162_RS02110 AB162_439 AB162_RS02110 443876 444346 + 30S ribosomal protein S7 gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02110 AB162_RS02115 AB162_440 fusA fusA 444395 446527 + elongation factor G EF-G%3B promotes GTP-dependent translocation of the ribosome during translation%3B many organisms have multiple copies of this gene gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02115 AB162_RS02120 AB162_441 tuf tuf 446586 447770 + elongation factor Tu EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02120 AB162_RS02125 AB162_442 AB162_RS02125 447787 448167 + hypothetical protein gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02125 AB162_RS02130 AB162_443 nusG nusG 448168 448713 + transcription antiterminator NusG Modulates Rho-dependent transcription termination gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02130 AB162_RS02135 AB162_444 AB162_RS02135 448758 449186 + 50S ribosomal protein L11 gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02135 AB162_RS02140 AB162_445 AB162_RS02140 449190 449882 + 50S ribosomal protein L1 gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02140 AB162_RS02145 AB162_446 AB162_RS02145 449998 450495 + 50S ribosomal protein L10 gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02145 AB162_RS02150 AB162_447 AB162_RS02150 450520 450885 + 50S ribosomal protein L7/L12 gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02150 AB162_RS02155 AB162_448 rpoB rpoB 451070 455095 + DNA-directed RNA polymerase subunit beta DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02155 AB162_RS02160 AB162_449 AB162_RS02160 455171 459394 + DNA-directed RNA polymerase subunit beta' DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02160 AB162_RS02165 AB162_450 murB murB 459422 460447 + UDP-N-acetylenolpyruvoylglucosamine reductase catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02165 AB162_RS02170 AB162_451 AB162_RS02170 460425 461423 + hypothetical protein gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02170 AB162_RS02175 AB162_452 AB162_RS02175 461473 461589 - 5S ribosomal RNA rRNA gene434 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02175 AB162_RS02180 AB162_453 AB162_RS02180 461615 464571 - 23S ribosomal RNA rRNA gene435 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02180 AB162_RS02185 AB162_454 AB162_RS02185 464778 466334 - 16S ribosomal RNA rRNA gene436 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02185 AB162_RS02190 AB162_455 AB162_RS02190 466667 468100 - dihydrolipoamide dehydrogenase E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex%3B catalyzes the oxidation of dihydrolipoamide to lipoamide gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02190 AB162_RS02195 AB162_456 AB162_RS02195 468157 469470 - branched-chain alpha-keto acid dehydrogenase subunit E2 gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02195 AB162_RS02200 AB162_457 aceE aceE 469486 472158 - pyruvate dehydrogenase E1 component%3B part of pyruvate dehydrogenase%3B forms a complex with DlaT and LpdC gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02200 AB162_RS02205 AB162_458 AB162_RS02205 472290 473180 + nicotinate-nucleotide pyrophosphorylase catalyzes the formation of pyridine-2%2C3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02205 AB162_RS02210 AB162_459 coaE coaE 473209 473832 + dephospho-CoA kinase catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B involved in coenzyme A biosynthesis gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02210 AB162_RS02215 AB162_460 secA secA 473964 476483 - preprotein translocase subunit SecA functions in protein export%3B can interact with acidic membrane phospholipids and the SecYEG protein complex%3B binds to preproteins%3B binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein%3B ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane%3B additional proteins SecD/F/YajC aid SecA recycling%3B exists in an equilibrium between monomers and dimers%3B may possibly form higher order oligomers%3B proteins in this cluster correspond SecA1%3B SecA2 is not essential and seems to play a role in secretion of a subset of proteins gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02215 AB162_RS02220 AB162_461 AB162_RS02220 476833 477345 + hypothetical protein gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02220 AB162_RS02225 AB162_462 AB162_RS02225 477403 478560 - cell division protein FtsZ GTPase%3B similar structure to tubulin%3B forms ring-shaped polymers at the site of cell division%3B other proteins such as FtsA%2C ZipA%2C and ZapA%2C interact with and regulate FtsZ function gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02225 AB162_RS02230 AB162_463 ftsA ftsA 478579 479844 - cell division protein FtsA ATP-binding involved in recruitment of FtsK to Z ring%3B essential cell division protein%3B colocalizes with FtsZ through direct interaction to the septal ring structure%3B structurally similar to eukaryotic actin%3B binds directly to the cell membrane gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02230 AB162_RS02235 AB162_464 AB162_RS02235 479883 480563 - hypothetical protein gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02235 AB162_RS02240 AB162_465 AB162_RS02240 480693 482123 - UDP-N-acetylmuramate--alanine ligase gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02240 AB162_RS02245 AB162_466 murG murG 482217 483278 - UDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase N-acetylglucosaminyl transferase%3B UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase%3B involved in cell wall formation%3B inner membrane-associated%3B last step of peptidoglycan synthesis gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02245 AB162_RS02250 AB162_467 AB162_RS02250 483290 484483 - cell division protein FtsW integral membrane protein involved in stabilizing FstZ ring during cell division gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02250 AB162_RS02255 AB162_468 murD murD 484483 485817 - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase UDP-N-acetylmuramoylalanine--D-glutamate ligase%3B involved in peptidoglycan biosynthesis%3B cytoplasmic%3B catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02255 AB162_RS02260 AB162_469 mraY mraY 485830 486924 - phospho-N-acetylmuramoyl-pentapeptide-transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02260 AB162_RS02265 AB162_470 murF murF 486918 488294 - UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02265 AB162_RS02270 AB162_471 murE murE 488303 489787 - UDP-N-acetylmuramoylalanyl-D-glutamate--2%2C6-diaminopimelate ligase involved in cell wall formation%3B peptidoglycan synthesis%3B cytoplasmic enzyme%3B catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02270 AB162_RS02275 AB162_472 AB162_RS02275 489815 491542 - cell division protein FtsI penicillin-binding protein 3%3B transpeptidase involved in septal peptidoglycan synthesis gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02275 AB162_RS02280 AB162_473 AB162_RS02280 491583 491900 - cell division protein FtsL gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02280 AB162_RS02285 AB162_474 AB162_RS02285 491914 492879 - 16S rRNA (cytosine(1402)-N(4))-methyltransferase gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02285 AB162_RS02290 AB162_475 AB162_RS02290 493356 494147 - methionine aminopeptidase catalyzes the removal of N-terminal amino acids from peptides and arylamides%3B generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn%2C Fe%2C or Mn gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02290 AB162_RS02295 AB162_476 AB162_RS02295 494461 495180 + 30S ribosomal protein S2 gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02295 AB162_RS02300 AB162_477 tsf tsf 495259 496080 + elongation factor Ts EF-Ts%3B functions during elongation stage of protein translation%3B forms a dimer%3B associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02300 AB162_RS02305 AB162_478 AB162_RS02305 496173 496898 + uridylate kinase gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02305 AB162_RS02310 AB162_479 frr frr 496936 497493 + ribosome recycling factor Rrf%3B Frr%3B ribosome-recycling factor%3B release factor 4%3B RF4%3B recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G%3B A GTPase-dependent process results in release of 50S from 70S%3B inhibited by release factor RF-1%3B essential for viability%3B structurally similar to tRNAs gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02310 AB162_RS02315 AB162_480 AB162_RS02315 497605 498801 + 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzes the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02315 AB162_RS02320 AB162_481 AB162_RS02320 498941 499699 + UDP pyrophosphate synthase catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02320 AB162_RS02325 AB162_482 cdsA cdsA 499709 500551 + CDP-diglyceride synthetase catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02325 AB162_RS02330 AB162_483 AB162_RS02330 500581 501939 + zinc metallopeptidase RseP catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02330 AB162_RS02335 AB162_484 AB162_RS02335 501941 504355 + outer membrane assembly protein part of a complex with YfgL%2C YfiO%2C and NlpB involved in outer membrane protein biosynthesis%3B involved in the assembly of outer membrane proteins gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02335 AB162_RS02340 AB162_485 AB162_RS02340 504426 504923 + molecular chaperone gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02340 AB162_RS02345 AB162_486 AB162_RS02345 505122 505571 + 3-hydroxyacyl-ACP dehydratase gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02345 AB162_RS02350 AB162_487 dnaE dnaE 505697 509188 + DNA polymerase III subunit alpha catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time%3B main replicative polymerase gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02350 AB162_RS02355 AB162_488 AB162_RS02355 509217 510176 + acetyl-CoA carboxylase subunit alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits%3B one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02355 AB162_RS02360 AB162_489 AB162_RS02360 511191 511880 + hypothetical protein gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02360 AB162_RS02365 AB162_490 AB162_RS02365 511965 512450 + RNA pyrophosphohydrolase hydrolyzes diadenosine polyphosphate gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02365 AB162_RS02370 AB162_491 AB162_RS02370 512562 513428 + prolipoprotein diacylglyceryl transferase gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02370 AB162_RS02375 AB162_492 AB162_RS02375 513451 514245 + thymidylate synthase gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02375 AB162_RS02380 AB162_493 recC recC 514285 517611 + exonuclease V subunit gamma catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides%3B component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02380 AB162_RS02385 AB162_494 AB162_RS02385 517718 521308 + exodeoxyribonuclease V subunit beta gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02385 AB162_RS02390 AB162_495 AB162_RS02390 521381 523294 + exodeoxyribonuclease V subunit alpha gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02390 AB162_RS02395 AB162_496 AB162_RS02395 523500 524133 + Crp/Fnr family transcriptional regulator cAMP receptor protein%3B complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02395 AB162_RS02400 AB162_497 AB162_RS02400 525012 526412 + DNA helicase unwinds double stranded DNA gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02400 AB162_RS02405 AB162_498 AB162_RS02405 526447 526522 + tRNA-Arg tRNA gene480 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02405 AB162_RS02410 AB162_499 dnaK dnaK 526799 528694 + molecular chaperone DnaK heat shock protein 70%3B assists in folding of nascent polypeptide chains%3B refolding of misfolded proteins%3B utilizes ATPase activity to help fold%3B co-chaperones are DnaJ and GrpE%3B multiple copies in some bacteria gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02410 AB162_RS02415 AB162_500 AB162_RS02415 528801 529921 + molecular chaperone DnaJ chaperone Hsp40%3B co-chaperone with DnaK%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C dnaK-independent fashion gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02415 AB162_RS02420 AB162_501 rpsT rpsT 529945 530205 - 30S ribosomal protein S20 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02420 AB162_RS02425 AB162_502 AB162_RS02425 530362 531309 + hypothetical protein gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02425 AB162_RS02430 AB162_503 ileS ileS 531345 534167 + isoleucine--tRNA ligase IleRS%3B catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile)%3B since isoleucine and other amino acids such as valine are similar%2C there are additional editing function in this enzyme%3B one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile)%3B there are two active sites%2C one for aminoacylation and one for editing%3B class-I aminoacyl-tRNA synthetase family type 1 subfamily%3B some organisms carry two different copies of this enzyme gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02430 AB162_RS02435 AB162_504 lspA lspA 534203 534709 + lipoprotein signal peptidase lipoprotein signal peptidase%3B integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02435 AB162_RS02440 AB162_505 ispH ispH 534718 535665 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B functions in the nonmevalonate isoprenoid biosynthesis pathway gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02440 AB162_RS02445 AB162_506 AB162_RS02445 535854 537050 + carbamoyl phosphate synthase small subunit catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways%3B forms an octamer composed of four CarAB dimers gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02445 AB162_RS02450 AB162_507 carB carB 537066 540323 + carbamoyl phosphate synthase large subunit four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate%3B CarB is responsible for the amidotransferase activity gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02450 AB162_RS02455 AB162_508 folA folA 540367 540861 + dihydrofolate reductase catalyzes the reduction of dihydrofolate to tetrahydrofolate gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02455 AB162_RS02460 AB162_509 AB162_RS02460 540897 541730 - diadenosine tetraphosphatase gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02460 AB162_RS02465 AB162_510 ksgA ksgA 541872 542669 - 16S rRNA methyltransferase in Escherichia coli this enzyme catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA%3B mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin%3B members of this protein family have secondary functions gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02465 AB162_RS02470 AB162_511 AB162_RS02470 542790 543914 - hypothetical protein gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02470 AB162_RS02475 AB162_RS02475 AB162_RS02475 544271 544603 + hypothetical protein gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02475 AB162_RS02480 AB162_513 AB162_RS02480 544682 544954 - hypothetical protein gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02480 AB162_RS02485 AB162_515 AB162_RS02485 544947 545384 - hypothetical protein gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02485 AB162_RS02490 AB162_516 smpB smpB 545455 545936 + SsrA-binding protein binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes%3B also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site%3B SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus%3B both the tmRNA and SmpB are regulated in cell cycle-dependent manner%3B functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02490 AB162_RS02495 AB162_518 rplI rplI 546548 547006 - 50S ribosomal protein L9 in Escherichia coli this protein is wrapped around the base of the L1 stalk gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02495 AB162_RS02500 AB162_519 rpsR rpsR 547082 547309 - 30S ribosomal protein S18 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%3B helps stabilize the platform of the 30S subunit gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02500 AB162_RS02505 AB162_520 AB162_RS02505 547332 547643 - primosomal replication protein N binds single-stranded DNA at the primosome assembly site gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02505 AB162_RS02510 AB162_521 rpsF rpsF 547643 548053 - 30S ribosomal protein S6 binds cooperatively with S18 to the S15-16S complex%2C allowing platform assembly to continue with S11 and S21 gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02510 AB162_RS02515 AB162_522 AB162_RS02515 548249 549028 - 23S rRNA methyltransferase Specifically methylates the ribose of guanosine 2251 in 23S rRNA gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02515 AB162_RS02520 AB162_523 AB162_RS02520 549094 551181 - exoribonuclease R 3'-5'exoribonuclease that acts nonspecifically on poly(A)%2C poly(U) and ribosomal RNAs gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02520 AB162_RS02525 AB162_524 AB162_RS02525 551451 552755 - adenylosuccinate synthetase catalyzes the formation of N6-(1%2C2%2C-dicarboxyethyl)-AMP from L-aspartate%2C inosine monophosphate and GTP in AMP biosynthesis gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02525 AB162_RS02530 AB162_525 AB162_RS02530 552893 553921 - cell division protein FtsH with HflK inhibits proteolysis of lambda cII protein by FtsH gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02530 AB162_RS02535 AB162_526 AB162_RS02535 553928 555112 - cell division protein FtsH with HflC inhibits proteolysis of lambda cII protein by FtsH gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02535 AB162_RS02540 AB162_527 AB162_RS02540 555181 556467 - GTPase HflX involved in modulation of proteins HflK and HflC%3B part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02540 AB162_RS02545 AB162_528 miaA miaA 556725 557675 - tRNA delta(2)-isopentenylpyrophosphate transferase IPP transferase%3B isopentenyltransferase%3B involved in tRNA modification%3B in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil%3B further tRNA modifications may occur%3B mutations in miaA result in defects in translation efficiency and fidelity gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02545 AB162_RS02550 AB162_529 AB162_RS02550 557668 559443 - DNA mismatch repair protein gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02550 AB162_RS02555 AB162_530 AB162_RS02555 559534 560760 - hypothetical protein gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02555 AB162_RS02560 AB162_531 AB162_RS02560 560832 561299 - tRNA threonylcarbamoyladenosine biosynthesis protein TsaE gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02560 AB162_RS02565 AB162_532 AB162_RS02565 561322 561879 - oligoribonuclease 3'-5' exoribonuclease specific for small oligoribonuclotides gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02565 AB162_RS02570 AB162_533 AB162_RS02570 562119 563003 + phosphatidylserine decarboxylase gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02570 AB162_RS02575 AB162_534 AB162_RS02575 563020 566343 + mechanosensitive channel protein gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02575 AB162_RS02580 AB162_535 AB162_RS02580 566375 567382 - poxB regulator PoxA poxA%3B regulates pyruvate oxidase poxB gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02580 AB162_RS02585 AB162_536 AB162_RS02585 567437 568003 - elongation factor P gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02585 AB162_RS02590 AB162_537 AB162_RS02590 568065 569090 + EF-P beta-lysylation protein EpmB gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02590 AB162_RS02595 AB162_538 groEL groEL 569227 570876 - molecular chaperone GroEL 60 kDa chaperone family%3B promotes refolding of misfolded polypeptides especially under stressful conditions%3B forms two stacked rings of heptamers to form a barrel-shaped 14mer%3B ends can be capped by GroES%3B misfolded proteins enter the barrel where they are refolded when GroES binds%3B many bacteria have multiple copies of the groEL gene which are active under different environmental conditions%3B the B.japonicum protein in this cluster is expressed constitutively%3B in Rhodobacter%2C Corynebacterium and Rhizobium this protein is essential for growth gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02595 AB162_RS02600 AB162_539 groES groES 570920 571213 - molecular chaperone GroES 10 kDa chaperonin%3B Cpn10%3B GroES%3B forms homoheptameric ring%3B binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it%3B folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES%3B release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02600 AB162_RS02605 AB162_540 aspA aspA 571475 572896 + aspartate ammonia-lyase catalyzes the formation of fumarate from aspartate gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02605 AB162_RS02610 AB162_541 AB162_RS02610 572980 573052 + tRNA-Phe tRNA gene521 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02610 AB162_RS02615 AB162_542 AB162_RS02615 573242 573844 - peroxiredoxin gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02615 AB162_RS02620 AB162_543 yajC yajC 574560 574898 + preprotein translocase subunit YajC member of preprotein translocase%3B forms a heterotrimer with SecD and SecF%3B links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02620 AB162_RS02625 AB162_544 secD secD 574923 576764 + preprotein translocase subunit SecD part of the preprotein secretory system%3B when complexed with proteins SecF and YajC%2C SecDFyajC stimulates the proton motive force-driven protein translocation%2C and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02625 AB162_RS02630 AB162_545 AB162_RS02630 576773 577726 + preprotein translocase subunit SecF gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02630 AB162_RS02635 AB162_546 ribD ribD 577873 579006 + 5-amino-6-(5-phosphoribosylamino)uracil reductase riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway%3B catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02635 AB162_RS02640 AB162_547 ribH ribH 579040 579507 + 6%2C7-dimethyl-8-ribityllumazine synthase RibE%3B 6%2C7-diimethyl-8-ribityllumazine synthase%3B DMRL synthase%3B lumazine synthase%3B beta subunit of riboflavin synthase%3B condenses 5-amino-6-(1'-D)-ribityl-amino-2%2C4(1H%2C3H)-pyrimidinedione with L-3%2C4-dihydrohy-2-butanone-4-phosphate to generate 6%2C6-dimethyl-8-lumazine (DMRL)%3B riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12)%3B involved in the last steps of riboflavin biosynthesis%3B forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli%3B in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02640 AB162_RS02645 AB162_548 nusB nusB 579536 579955 + transcription antiterminator NusB Regulates rRNA biosynthesis by transcriptional antitermination gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02645 AB162_RS02650 AB162_549 AB162_RS02650 580111 580608 + phosphatidylglycerophosphatase hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02650 AB162_RS02655 AB162_551 AB162_RS02655 581612 582169 - inorganic pyrophosphatase catalyzes the hydrolysis of pyrophosphate to phosphate gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02655 AB162_RS02660 AB162_552 AB162_RS02660 582276 584009 - proline--tRNA ligase catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02660 AB162_RS02665 AB162_553 AB162_RS02665 584162 584243 - tRNA-Leu tRNA gene532 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02665 AB162_RS02670 AB162_554 ppnK ppnK 584378 585259 - inorganic polyphosphate kinase catalyzes the phosphorylation of NAD to NADP gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02670 AB162_RS02675 AB162_555 AB162_RS02675 585382 585996 + heat -hock protein GrpE with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%3B may act as a thermosensor gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02675 AB162_RS02680 AB162_557 AB162_RS02680 586668 588281 - L-aspartate oxidase catalyzes the formation of oxaloacetate from L-aspartate gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02680 AB162_RS02685 AB162_558 AB162_RS02685 588326 588398 - tRNA-Met tRNA gene536 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02685 AB162_RS02690 AB162_559 AB162_RS02690 588465 590348 - RNA polymerase subunit sigma sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this is the primary sigma factor of bacteria gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02690 AB162_RS02695 AB162_560 dnaG dnaG 590419 592170 - DNA primase synthesizes RNA primers at the replication forks gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02695 AB162_RS02700 AB162_561 rpsU rpsU 592243 592458 - 30S ribosomal protein S21 a small basic protein that is one of the last in the subunit assembly%3B omission does not prevent assembly but the subunit is inactive%3B binds central domain of 16S rRNA gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02700 AB162_RS02705 AB162_562 AB162_RS02705 592567 593592 + UGMP family protein universal genome maintenance protein%3B Kae1/Qri7/OSGEP/YgjD family protein%3B in Archaea%2C some Kae1 are found as fusion proteins similar to two distinct proteins in yeast that are involved in the KEOPS complex%3B kinase associated endopeptidase 1 (Kae1) and a serine/threonine protein kinase (Bud32)%3B in Pyrococcus Kae1 has atypical AP endonuclease activity and inhibits the kinase activity of Bud32%3B the protein is essential in Escherichia coli and Bacillus subtilis gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02705 AB162_RS02710 AB162_563 folB folB 593725 594081 + dihydroneopterin aldolase catalyzes the conversion of 7%2C8-dihydroneopterin to 6-hydroxymethyl-7%2C8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02710 AB162_RS02715 AB162_564 AB162_RS02715 594103 594942 + UDP pyrophosphate phosphatase BacA%3B phosphatase activity in Escherichia coli not kinase%3B involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02715 AB162_RS02720 AB162_565 AB162_RS02720 595001 596203 - tRNA nucleotidyl transferase gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02720 AB162_RS02725 AB162_566 AB162_RS02725 596381 596629 - hypothetical protein gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02725 AB162_RS02730 AB162_567 ribB ribB 596893 597531 + 3%2C4-dihydroxy-2-butanone 4-phosphate synthase DHBP synthase%3B functions during riboflavin biosynthesis gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02730 AB162_RS02735 AB162_568 AB162_RS02735 597575 598303 - acyl-phosphate glycerol 3-phosphate acyltransferase gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02735 AB162_RS02740 AB162_569 AB162_RS02740 598379 599785 - DNA repair protein RadA Sms%3B stabilizes the strand-invasion intermediate during the DNA repair%3B involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02740 AB162_RS02745 AB162_570 AB162_RS02745 599991 600422 - hypothetical protein gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02745 AB162_RS02750 AB162_571 AB162_RS02750 600615 602246 - DEAD/DEAH box helicase participates in the assembly of the large subunit of the ribosome%3B plays a key role in optimal cell growth at low temperature and is required for normal cell division gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02750 AB162_RS02755 AB162_572 AB162_RS02755 602765 604888 - polynucleotide phosphorylase/polyadenylase gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02755 AB162_RS02760 AB162_573 AB162_RS02760 605057 605326 - 30S ribosomal protein S15 gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02760 AB162_RS02765 AB162_574 truB truB 605452 606402 - tRNA pseudouridine synthase B catalyzes isomerization of specific uridines in RNA to pseudouridine%3B responsible for residues in T loops of many tRNAs gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02765 AB162_RS02770 AB162_575 rbfA rbfA 606420 606812 - ribosome-binding factor A associates with free 30S ribosomal subunits%3B essential for efficient processing of 16S rRNA%3B in Escherichia coli rbfA is induced by cold shock gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02770 AB162_RS02775 AB162_576 infB infB 606917 609550 - translation initiation factor IF-2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02775 AB162_RS02780 AB162_577 nusA nusA 609566 611050 - transcription elongation factor NusA modifies transcription through interactions with RNA polymerase affecting elongation%2C readthrough%2C termination%2C and antitermination gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02780 AB162_RS02785 AB162_578 AB162_RS02785 611310 611386 - tRNA-Met tRNA gene556 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02785 AB162_RS02790 AB162_579 AB162_RS02790 611456 611545 - tRNA-Leu tRNA gene557 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02790 AB162_RS02795 AB162_RS02795 AB162_RS02795 611590 611933 - hypothetical protein gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02795 AB162_RS02800 AB162_582 glmM glmM 612055 613386 - phosphoglucosamine mutase catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02800 AB162_RS02805 AB162_583 folP folP 613383 614219 - dihydropteroate synthase catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine diphosphate and 4-aminobenzoate gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02805 AB162_RS02810 AB162_584 hflB hflB 614367 616184 - ATP-dependent metalloprotease inner membrane metalloprotease%3B may be involved in degradation of aberrant cytoplasmic and membrane proteins gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02810 AB162_RS02815 AB162_585 rrmJ rrmJ 616245 616874 - 23S rRNA methyltransferase Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02815 AB162_RS02820 AB162_586 greA greA 617030 617512 - transcription elongation factor GreA necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02820 AB162_RS02825 AB162_RS02825 AB162_RS02825 617918 619120 + D-alanyl-D-alanine carboxypeptidase penicillin binding protein 4%3B penicillin sensitive%3B catalyzes the formation of D-alanine from D-alanyl-D-alanine%3B one of four%2C DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02825 AB162_RS02830 AB162_588 obgE obgE 619214 620284 - GTPase CgtA ObgE%3B essential GTPase%3B exhibits high exchange rate for GTP/GDP%3B associates with 50S ribosomal subunit%3B involved in regulation of chromosomal replication gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02830 AB162_RS02835 AB162_589 rpmA rpmA 620331 620597 - 50S ribosomal protein L27 involved in the peptidyltransferase reaction during translation gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02835 AB162_RS02840 AB162_590 rplU rplU 620625 620936 - 50S ribosomal protein L21 gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02840 AB162_RS02845 AB162_591 AB162_RS02845 621086 622072 + octaprenyl diphosphate synthase gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02845 AB162_RS02850 AB162_592 AB162_RS02850 622191 623369 + phosphoglycerate kinase gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02850 AB162_RS02855 AB162_593 AB162_RS02855 623389 624468 + fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1%2C6%2C bisphosphate gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02855 AB162_RS02860 AB162_594 AB162_RS02860 624580 625239 + ribose 5-phosphate isomerase gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02860 AB162_RS02865 AB162_595 AB162_RS02865 625246 625881 - hypothetical protein gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02865 AB162_RS02870 AB162_596 AB162_RS02870 626321 627493 + 2-octaprenyl-6-methoxyphenyl hydroxylase Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1%2C4-benzoquinone gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02870 AB162_RS02875 AB162_597 AB162_RS02875 627517 628734 + oxidoreductase gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02875 AB162_RS02880 AB162_598 guaA guaA 629377 630960 - GMP synthase contains glutamine-hydrolyzing domain and glutamine amidotransferase%3B GMP-binding domain%3B functions to produce GMP from XMP in the IMP pathway gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02880 AB162_RS02885 AB162_599 AB162_RS02885 630988 632445 - inosine-5-monophosphate dehydrogenase gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02885 AB162_RS02890 AB162_p001 AB162_RS02890 13 840 + replication protein gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02890 AB162_RS02895 AB162_p002 AB162_RS02895 858 1334 - heat-shock protein gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02895 AB162_RS02900 AB162_p005 AB162_RS02900 1448 2353 - protease gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02900 AB162_RS02905 AB162_p003 AB162_RS02905 2593 2949 - hypothetical protein gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=AB162_RS02905