locus-tag	class	description
A33Y_RS00015	COG0356	it plays a direct role in the translocation of protons across the membrane
A33Y_RS00055	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A33Y_RS00060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A33Y_RS00085	COG0024	Methionine aminopeptidase
A33Y_RS00105	COG0587	DNA-directed DNA polymerase activity
A33Y_RS00115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A33Y_RS00135	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A33Y_RS00140	COG0129	dihydroxy-acid dehydratase activity
A33Y_RS00150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A33Y_RS00160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A33Y_RS00165	COG0719	Fe-S assembly protein
A33Y_RS00185	COG0482	sulfurtransferase activity
A33Y_RS00190	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A33Y_RS00200	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A33Y_RS00210	COG0512	Glutamine amidotransferase of anthranilate synthase
A33Y_RS00230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A33Y_RS00235	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A33Y_RS00255	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A33Y_RS00265	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A33Y_RS00285	COG0539	negative regulation of cytoplasmic translation
A33Y_RS00330	COG0358	DNA primase activity
A33Y_RS00335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A33Y_RS00340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A33Y_RS00345	COG0107	imidazoleglycerol-phosphate synthase activity
A33Y_RS00350	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A33Y_RS00355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A33Y_RS00360	COG0131	Imidazoleglycerol-phosphate dehydratase
A33Y_RS00400	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A33Y_RS00420	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A33Y_RS00425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A33Y_RS00450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A33Y_RS00460	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A33Y_RS00480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A33Y_RS00495	COG0066	3-isopropylmalate dehydratase activity
A33Y_RS00505	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A33Y_RS00520	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A33Y_RS00530	COG2176	DNA-directed DNA polymerase activity
A33Y_RS00540	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A33Y_RS00560	COG0481	GTPase activity
A33Y_RS00565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A33Y_RS00570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A33Y_RS00580	COG0495	leucyl-tRNA aminoacylation
A33Y_RS00605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A33Y_RS00655	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A33Y_RS00660	COG0525	valine-tRNA ligase activity
A33Y_RS00665	COG0450	alkyl hydroperoxide reductase
A33Y_RS00670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A33Y_RS00690	COG0180	Tryptophanyl-tRNA synthetase
A33Y_RS00700	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A33Y_RS00720	COG0460	homoserine dehydrogenase
A33Y_RS00735	COG0228	four-way junction DNA binding
A33Y_RS00745	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A33Y_RS00755	COG0028	Belongs to the TPP enzyme family
A33Y_RS00760	COG0564	pseudouridine synthase activity
A33Y_RS00765	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A33Y_RS00775	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A33Y_RS00810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A33Y_RS00855	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A33Y_RS00895	COG0051	transcription antitermination factor activity, RNA binding
A33Y_RS00930	COG0222	ribosome binding
A33Y_RS00945	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A33Y_RS00965	COG1845	cytochrome c oxidase, subunit III
A33Y_RS00970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A33Y_RS00975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A33Y_RS00990	COG0124	histidyl-tRNA synthetase
A33Y_RS01000	COG0242	peptide deformylase activity
A33Y_RS01010	COG0019	diaminopimelate decarboxylase activity
A33Y_RS01015	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A33Y_RS01030	COG1278	Cold shock
A33Y_RS01045	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A33Y_RS01050	COG0305	Participates in initiation and elongation during chromosome replication
A33Y_RS01055	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A33Y_RS01070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A33Y_RS01075	COG0579	oxidoreductase
A33Y_RS01080	COG0527	aspartate kinase activity
A33Y_RS01085	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A33Y_RS01095	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A33Y_RS01110	COG0088	Forms part of the polypeptide exit tunnel
A33Y_RS01115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family