locus-tag	class	description
RSDT_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RSDT_RS00010	COG0287	Prephenate dehydrogenase
RSDT_RS00010	COG1605	Chorismate mutase
RSDT_RS00015	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RSDT_RS00020	COG0077	Prephenate dehydratase
RSDT_RS00020	COG1605	Chorismate mutase
RSDT_RS00025	COG1465	3-dehydroquinate synthase
RSDT_RS00030	COG1830	Aldolase
RSDT_RS00035	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RSDT_RS00070	COG1797	cobyrinic acid a,c-diamide synthase activity
RSDT_RS00150	COG2855	membrane
RSDT_RS00160	COG0776	regulation of translation
RSDT_RS00165	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RSDT_RS00175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RSDT_RS00180	COG0107	imidazoleglycerol-phosphate synthase activity
RSDT_RS00190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RSDT_RS00195	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RSDT_RS00205	COG0779	Required for maturation of 30S ribosomal subunits
RSDT_RS00210	COG0195	Participates in both transcription termination and antitermination
RSDT_RS00210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RSDT_RS00220	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RSDT_RS00245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RSDT_RS00255	COG1185	polyribonucleotide nucleotidyltransferase activity
RSDT_RS00265	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RSDT_RS00270	COG3872	metal-dependent enzyme
RSDT_RS00275	COG0254	rRNA binding
RSDT_RS00280	COG1253	flavin adenine dinucleotide binding
RSDT_RS00285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RSDT_RS00290	COG4957	zinc ion binding
RSDT_RS00300	COG0363	glucosamine-6-phosphate deaminase activity
RSDT_RS00305	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
RSDT_RS00315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RSDT_RS00320	COG1053	succinate dehydrogenase
RSDT_RS00325	COG3875	lactate racemase activity
RSDT_RS00345	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RSDT_RS00360	COG1538	Outer membrane efflux protein
RSDT_RS00375	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RSDT_RS00375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RSDT_RS00385	COG2095	MarC family integral membrane protein
RSDT_RS00395	COG3177	Filamentation induced by cAMP protein fic
RSDT_RS00405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RSDT_RS00425	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RSDT_RS00435	COG0180	Tryptophanyl-tRNA synthetase
RSDT_RS00440	COG1994	Peptidase M50
RSDT_RS00445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RSDT_RS00455	COG0330	HflC and HflK could
RSDT_RS00465	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
RSDT_RS00485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RSDT_RS00490	COG2089	acid synthase
RSDT_RS00505	COG0315	cyclic pyranopterin monophosphate synthase activity
RSDT_RS00510	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RSDT_RS00515	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RSDT_RS00520	COG1136	(ABC) transporter
RSDT_RS00530	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RSDT_RS00535	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
RSDT_RS00540	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
RSDT_RS00555	COG0662	Cupin 2, conserved barrel domain protein
RSDT_RS00570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RSDT_RS00575	COG0538	isocitrate dehydrogenase activity
RSDT_RS00580	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RSDT_RS00595	COG1408	metallophosphoesterase
RSDT_RS00600	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RSDT_RS00605	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RSDT_RS00610	COG0509	glycine decarboxylation via glycine cleavage system
RSDT_RS00615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RSDT_RS00620	COG0095	Lipoate-protein ligase
RSDT_RS00625	COG0084	hydrolase, TatD family'
RSDT_RS00635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RSDT_RS00650	COG0129	dihydroxy-acid dehydratase activity
RSDT_RS00655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RSDT_RS00665	COG0564	pseudouridine synthase activity
RSDT_RS00680	COG2721	sulfolactate sulfo-lyase activity
RSDT_RS00685	COG2721	sulfolactate sulfo-lyase activity
RSDT_RS00705	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RSDT_RS00710	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RSDT_RS00735	COG1127	ABC transporter
RSDT_RS00740	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RSDT_RS00765	COG0571	ribonuclease III activity
RSDT_RS00775	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RSDT_RS00785	COG0740	serine-type endopeptidase activity
RSDT_RS00790	COG0544	peptidyl-prolyl cis-trans isomerase activity
RSDT_RS00805	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RSDT_RS00810	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RSDT_RS00815	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RSDT_RS00820	COG0791	NLP P60 protein
RSDT_RS00830	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RSDT_RS00845	COG4608	Belongs to the ABC transporter superfamily
RSDT_RS00855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RSDT_RS00930	COG3028	Belongs to the UPF0307 family
RSDT_RS00940	COG0315	cyclic pyranopterin monophosphate synthase activity
RSDT_RS00940	COG0521	Mo-molybdopterin cofactor biosynthetic process
RSDT_RS00945	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RSDT_RS00950	COG0552	protein localization to endoplasmic reticulum
RSDT_RS00980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RSDT_RS01005	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RSDT_RS01020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RSDT_RS01030	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
RSDT_RS01035	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RSDT_RS01040	COG0145	ligase activity
RSDT_RS01045	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RSDT_RS01050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RSDT_RS01055	COG0589	response to stress
RSDT_RS01060	COG0525	valine-tRNA ligase activity
RSDT_RS01095	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RSDT_RS01100	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RSDT_RS01105	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RSDT_RS01110	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RSDT_RS01130	COG1847	R3H domain protein
RSDT_RS01130	COG1847	R3H domain protein
RSDT_RS01135	COG0706	membrane insertase activity
RSDT_RS01140	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RSDT_RS01145	COG0594	ribonuclease P activity
RSDT_RS01150	COG0230	Belongs to the bacterial ribosomal protein bL34 family
RSDT_RS01155	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RSDT_RS01170	COG0484	heat shock protein binding
RSDT_RS01190	COG0505	Belongs to the CarA family
RSDT_RS01195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RSDT_RS01220	COG0028	Belongs to the TPP enzyme family
RSDT_RS01225	COG0440	acetolactate synthase activity
RSDT_RS01230	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RSDT_RS01235	COG0563	adenylate kinase activity
RSDT_RS01245	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
RSDT_RS01260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RSDT_RS01265	COG1121	(ABC) transporter
RSDT_RS01275	COG0009	L-threonylcarbamoyladenylate synthase
RSDT_RS01290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RSDT_RS01295	COG0018	arginyl-trna synthetase
RSDT_RS01305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RSDT_RS01330	COG0444	Belongs to the ABC transporter superfamily
RSDT_RS01335	COG1739	Uncharacterized protein family UPF0029
RSDT_RS01350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RSDT_RS01355	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RSDT_RS01360	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RSDT_RS01365	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RSDT_RS01370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RSDT_RS01380	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RSDT_RS01385	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RSDT_RS01400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RSDT_RS01410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RSDT_RS01425	COG0356	it plays a direct role in the translocation of protons across the membrane
RSDT_RS01450	COG0375	protein maturation
RSDT_RS01460	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RSDT_RS01470	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RSDT_RS01475	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
RSDT_RS01480	COG0651	ATP synthesis coupled electron transport
RSDT_RS01490	COG0543	2 iron, 2 sulfur cluster binding
RSDT_RS01495	COG0493	'glutamate synthase
RSDT_RS01515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RSDT_RS01535	COG1045	serine acetyltransferase
RSDT_RS01540	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RSDT_RS01550	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RSDT_RS01565	COG2239	Acts as a magnesium transporter
RSDT_RS01575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RSDT_RS01585	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
RSDT_RS01630	COG0670	Belongs to the BI1 family
RSDT_RS01650	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RSDT_RS01655	COG1959	2 iron, 2 sulfur cluster binding
RSDT_RS01675	COG2890	protein-(glutamine-N5) methyltransferase activity
RSDT_RS01690	COG1353	crispr-associated protein
RSDT_RS01710	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RSDT_RS01715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RSDT_RS01725	COG0138	bifunctional purine biosynthesis protein purh
RSDT_RS01735	COG1077	Cell shape determining protein MreB Mrl
RSDT_RS01750	COG0149	triose-phosphate isomerase activity
RSDT_RS01755	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RSDT_RS01770	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RSDT_RS01825	COG0085	RNA polymerase activity
RSDT_RS01835	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RSDT_RS01840	COG0081	regulation of translation
RSDT_RS01845	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RSDT_RS01850	COG0250	Participates in transcription elongation, termination and antitermination
RSDT_RS01870	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RSDT_RS01885	COG0791	NLP P60 protein
RSDT_RS01895	COG1469	GTP cyclohydrolase I activity
RSDT_RS01900	COG0864	Transcriptional regulator
RSDT_RS01910	COG3956	TIGRFAM MazG family protein
RSDT_RS01930	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
RSDT_RS01935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RSDT_RS01940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RSDT_RS01945	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RSDT_RS01955	COG0193	aminoacyl-tRNA hydrolase activity
RSDT_RS01965	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RSDT_RS01970	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RSDT_RS01985	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RSDT_RS01990	COG4783	chaperone-mediated protein folding
RSDT_RS01995	COG0215	cysteine-tRNA ligase activity
RSDT_RS02000	COG0698	ribose 5-phosphate isomerase
RSDT_RS02015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RSDT_RS02020	COG1410	methionine synthase
RSDT_RS02020	COG0646	methionine synthase
RSDT_RS02025	COG0454	-acetyltransferase
RSDT_RS02045	COG1674	ftsk spoiiie
RSDT_RS02050	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RSDT_RS02055	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RSDT_RS02065	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RSDT_RS02070	COG0492	ferredoxin-NADP+ reductase activity
RSDT_RS02075	COG3118	belongs to the thioredoxin family
RSDT_RS02080	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RSDT_RS02110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RSDT_RS02115	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RSDT_RS02135	COG0497	DNA recombination
RSDT_RS02140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSDT_RS02145	COG0601	transmembrane transport
RSDT_RS02160	COG1187	pseudouridine synthase activity
RSDT_RS02170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RSDT_RS02175	COG4974	Belongs to the 'phage' integrase family
RSDT_RS02225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RSDT_RS02230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RSDT_RS02235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RSDT_RS02240	COG0772	Belongs to the SEDS family
RSDT_RS02245	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RSDT_RS02250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RSDT_RS02255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RSDT_RS02260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RSDT_RS02275	COG0275	rRNA processing
RSDT_RS02290	COG2033	superoxide reductase activity
RSDT_RS02295	COG1773	rubredoxin
RSDT_RS02340	COG0574	Belongs to the PEP-utilizing enzyme family
RSDT_RS02340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RSDT_RS02345	COG0439	Biotin carboxylase
RSDT_RS02355	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RSDT_RS02360	COG1480	7TM receptor with intracellular HD hydrolase
RSDT_RS02380	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RSDT_RS02400	COG0586	Pfam SNARE associated Golgi protein
RSDT_RS02405	COG1119	ATPase activity
RSDT_RS02410	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RSDT_RS02415	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
RSDT_RS02450	COG0751	glycine-tRNA ligase activity
RSDT_RS02455	COG0752	glycyl-tRNA synthetase alpha subunit
RSDT_RS02460	COG1381	Involved in DNA repair and RecF pathway recombination
RSDT_RS02470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RSDT_RS02475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RSDT_RS02495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RSDT_RS02495	COG1648	precorrin-2 dehydrogenase activity
RSDT_RS02500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RSDT_RS02505	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RSDT_RS02510	COG0037	tRNA processing
RSDT_RS02520	COG1902	pentaerythritol trinitrate reductase activity
RSDT_RS02520	COG0446	pyridine nucleotide-disulphide oxidoreductase
RSDT_RS02525	COG0069	glutamate synthase activity
RSDT_RS02550	COG0436	Aminotransferase
RSDT_RS02555	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RSDT_RS02575	COG0326	Molecular chaperone. Has ATPase activity
RSDT_RS02585	COG1494	fructose-1,6-bisphosphatase
RSDT_RS02590	COG0756	dUTP diphosphatase activity
RSDT_RS02625	COG0672	)-iron permease
RSDT_RS02630	COG3470	protein probably involved in high-affinity Fe2 transport
RSDT_RS02640	COG1136	(ABC) transporter
RSDT_RS02640	COG0577	efflux transmembrane transporter activity
RSDT_RS02645	COG0577	efflux transmembrane transporter activity
RSDT_RS02650	COG1136	(ABC) transporter
RSDT_RS02650	COG0577	efflux transmembrane transporter activity
RSDT_RS02660	COG0776	regulation of translation
RSDT_RS02665	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RSDT_RS02670	COG0815	Transfers the fatty acyl group on membrane lipoproteins
RSDT_RS02675	COG4535	Mg2 and Co2 transporter CorC
RSDT_RS02680	COG0445	tRNA wobble uridine modification
RSDT_RS02700	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RSDT_RS02710	COG1136	(ABC) transporter
RSDT_RS02710	COG0577	efflux transmembrane transporter activity
RSDT_RS02715	COG1136	(ABC) transporter
RSDT_RS02715	COG0577	efflux transmembrane transporter activity
RSDT_RS02725	COG4822	anaerobic cobalamin biosynthetic process
RSDT_RS02730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSDT_RS02770	COG0318	PFAM AMP-dependent synthetase and ligase
RSDT_RS02780	COG0138	bifunctional purine biosynthesis protein purh
RSDT_RS02785	COG1797	cobyrinic acid a,c-diamide synthase activity
RSDT_RS02795	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RSDT_RS02815	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RSDT_RS02825	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
RSDT_RS02830	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RSDT_RS02835	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RSDT_RS02850	COG0351	phosphomethylpyrimidine kinase
RSDT_RS02855	COG0612	Peptidase, M16
RSDT_RS02890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RSDT_RS02915	COG0154	amidase activity
RSDT_RS02920	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RSDT_RS02925	COG0443	Heat shock 70 kDa protein
RSDT_RS02930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RSDT_RS02935	COG2011	ABC-type metal ion transport system permease component
RSDT_RS02940	COG1464	Belongs to the NlpA lipoprotein family
RSDT_RS02950	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RSDT_RS02960	COG2226	methyltransferase
RSDT_RS02970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RSDT_RS02985	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RSDT_RS02990	COG0438	transferase activity, transferring glycosyl groups
RSDT_RS02990	COG0297	glycogen (starch) synthase activity
RSDT_RS03000	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RSDT_RS03015	COG0310	cobalt ion transport
RSDT_RS03030	COG1122	ATPase activity
RSDT_RS03040	COG0268	Binds directly to 16S ribosomal RNA
RSDT_RS03050	COG0632	four-way junction helicase activity
RSDT_RS03055	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RSDT_RS03085	COG0392	lysyltransferase activity
RSDT_RS03090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RSDT_RS03095	COG0628	permease
RSDT_RS03100	COG1686	Belongs to the peptidase S11 family
RSDT_RS03115	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RSDT_RS03130	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
RSDT_RS03150	COG5557	Pfam Polysulphide reductase, NrfD
RSDT_RS03155	COG0437	4 iron, 4 sulfur cluster binding
RSDT_RS03155	COG3064	Membrane
RSDT_RS03160	COG0484	heat shock protein binding
RSDT_RS03165	COG0101	tRNA pseudouridine synthase activity
RSDT_RS03170	COG1968	undecaprenyl-diphosphatase activity
RSDT_RS03185	COG1774	PSP1 C-terminal conserved region
RSDT_RS03195	COG0165	Argininosuccinate lyase
RSDT_RS03205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RSDT_RS03215	COG1193	negative regulation of DNA recombination
RSDT_RS03220	COG0358	DNA primase activity
RSDT_RS03250	COG0277	FAD linked oxidase domain protein
RSDT_RS03265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RSDT_RS03265	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
RSDT_RS03270	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RSDT_RS03305	COG1722	exodeoxyribonuclease VII activity
RSDT_RS03315	COG0442	prolyl-tRNA aminoacylation
RSDT_RS03320	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RSDT_RS03325	COG0012	GTP binding
RSDT_RS03330	COG0159	tryptophan synthase activity
RSDT_RS03335	COG0133	tryptophan synthase activity
RSDT_RS03340	COG0135	phosphoribosylanthranilate isomerase activity
RSDT_RS03345	COG0134	indole-3-glycerol-phosphate synthase activity
RSDT_RS03350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RSDT_RS03360	COG0708	Exodeoxyribonuclease III
RSDT_RS03380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RSDT_RS03390	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RSDT_RS03395	COG2204	response regulator
RSDT_RS03405	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
RSDT_RS03415	COG0019	diaminopimelate decarboxylase activity
RSDT_RS03425	COG1047	Peptidyl-prolyl cis-trans
RSDT_RS03430	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
RSDT_RS03435	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
RSDT_RS03440	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
RSDT_RS03450	COG1027	Aspartate ammonia-lyase
RSDT_RS03455	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
RSDT_RS03460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RSDT_RS03475	COG0540	Belongs to the ATCase OTCase family
RSDT_RS03480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RSDT_RS03495	COG0436	Aminotransferase
RSDT_RS03535	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RSDT_RS03570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RSDT_RS03570	COG0475	glutathione-regulated potassium exporter activity
RSDT_RS03575	COG0587	DNA-directed DNA polymerase activity
RSDT_RS03580	COG0720	synthase
RSDT_RS03590	COG0436	Aminotransferase
RSDT_RS03595	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RSDT_RS03600	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RSDT_RS03615	COG1233	COG1233 Phytoene dehydrogenase and related
RSDT_RS03630	COG2871	sodium ion transport
RSDT_RS03665	COG0233	cytoplasmic translational termination
RSDT_RS03680	COG1166	arginine decarboxylase activity
RSDT_RS03695	COG2221	Nitrite and sulphite reductase 4Fe-4S
RSDT_RS03700	COG2221	Nitrite and sulphite reductase 4Fe-4S
RSDT_RS03710	COG0306	phosphate transporter
RSDT_RS03725	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RSDT_RS03730	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RSDT_RS03735	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RSDT_RS03745	COG0582	viral genome integration into host DNA
RSDT_RS03760	COG0778	Nitroreductase
RSDT_RS03775	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
RSDT_RS03785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RSDT_RS03810	COG1546	Belongs to the CinA family
RSDT_RS03810	COG1058	Belongs to the CinA family
RSDT_RS03815	COG0322	excinuclease ABC activity
RSDT_RS03860	COG0582	viral genome integration into host DNA
RSDT_RS03870	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RSDT_RS03885	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RSDT_RS03890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RSDT_RS03895	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RSDT_RS03910	COG0488	(ABC) transporter
RSDT_RS03920	COG1660	Displays ATPase and GTPase activities
RSDT_RS03930	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
RSDT_RS03935	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RSDT_RS03950	COG0181	hydroxymethylbilane synthase activity
RSDT_RS03955	COG1067	ATP-dependent peptidase activity
RSDT_RS03985	COG0735	belongs to the Fur family
RSDT_RS03995	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RSDT_RS04000	COG0375	protein maturation
RSDT_RS04005	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RSDT_RS04025	COG0772	Belongs to the SEDS family
RSDT_RS04030	COG0768	penicillin binding
RSDT_RS04040	COG1792	Involved in formation and maintenance of cell shape
RSDT_RS04045	COG1077	Cell shape determining protein MreB Mrl
RSDT_RS04055	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RSDT_RS04060	COG3481	metal-dependent phosphohydrolase, HD sub domain
RSDT_RS04065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RSDT_RS04130	COG0519	Catalyzes the synthesis of GMP from XMP
RSDT_RS04150	COG0613	PHP domain protein
RSDT_RS04165	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RSDT_RS04175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RSDT_RS04195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RSDT_RS04200	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RSDT_RS04205	COG0052	Belongs to the universal ribosomal protein uS2 family
RSDT_RS04210	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RSDT_RS04215	COG0010	Belongs to the arginase family
RSDT_RS04220	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RSDT_RS04225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RSDT_RS04235	COG0049	tRNA binding
RSDT_RS04240	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RSDT_RS04265	COG2827	Endonuclease containing a URI domain
RSDT_RS04270	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RSDT_RS04270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RSDT_RS04285	COG0194	GDP metabolic process
RSDT_RS04290	COG2052	Domain of unknown function (DUF370)
RSDT_RS04295	COG1561	YicC-like family, N-terminal region
RSDT_RS04305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RSDT_RS04305	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RSDT_RS04355	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RSDT_RS04360	COG0542	response to heat
RSDT_RS04365	COG0484	heat shock protein binding
RSDT_RS04405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RSDT_RS04425	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RSDT_RS04440	COG0513	Belongs to the DEAD box helicase family
RSDT_RS04450	COG1217	gtp-binding protein TYPA
RSDT_RS04455	COG0439	Biotin carboxylase
RSDT_RS04475	COG0629	single-stranded DNA binding
RSDT_RS04480	COG2046	Belongs to the sulfate adenylyltransferase family
RSDT_RS04515	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RSDT_RS04525	COG0210	DNA helicase
RSDT_RS04530	COG0826	peptidase U32
RSDT_RS04540	COG2814	Major facilitator Superfamily
RSDT_RS04545	COG0527	aspartate kinase activity
RSDT_RS04550	COG0006	proline dipeptidase activity
RSDT_RS04555	COG0653	protein targeting
RSDT_RS04560	COG2204	response regulator
RSDT_RS04570	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RSDT_RS04575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RSDT_RS04610	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RSDT_RS04615	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RSDT_RS04620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RSDT_RS04625	COG1862	Preprotein translocase
RSDT_RS04630	COG1530	ribonuclease E activity
RSDT_RS04635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RSDT_RS04645	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RSDT_RS04655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RSDT_RS04710	COG3608	succinylglutamate desuccinylase aspartoacylase
RSDT_RS04710	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RSDT_RS04725	COG2233	PERMEase
RSDT_RS04730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RSDT_RS04730	COG0493	'glutamate synthase
RSDT_RS04735	COG0402	S-adenosylhomocysteine deaminase activity
RSDT_RS04745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RSDT_RS04755	COG0549	Belongs to the carbamate kinase family
RSDT_RS04760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RSDT_RS04770	COG0251	oxidation-reduction process
RSDT_RS04785	COG2835	tetraacyldisaccharide 4'-kinase activity
RSDT_RS04790	COG0424	maF-like protein
RSDT_RS04815	COG0285	dihydrofolate synthase activity
RSDT_RS04825	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RSDT_RS04825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RSDT_RS04830	COG0736	holo-[acyl-carrier-protein] synthase activity
RSDT_RS04840	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
RSDT_RS04845	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
RSDT_RS04850	COG1592	Rubrerythrin
RSDT_RS04855	COG1132	(ABC) transporter
RSDT_RS04885	COG0688	phosphatidylethanolamine metabolic process
RSDT_RS04890	COG1183	phosphatidylcholine synthase activity
RSDT_RS04895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RSDT_RS04900	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RSDT_RS04905	COG0066	3-isopropylmalate dehydratase activity
RSDT_RS04910	COG0473	3-isopropylmalate dehydrogenase activity
RSDT_RS04920	COG0126	phosphoglycerate kinase activity
RSDT_RS04925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RSDT_RS04930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RSDT_RS04940	COG0072	phenylalanine-tRNA ligase activity
RSDT_RS04940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RSDT_RS04950	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RSDT_RS04955	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RSDT_RS04960	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RSDT_RS04965	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RSDT_RS04970	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RSDT_RS04985	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
RSDT_RS05005	COG1002	Type II restriction enzyme, methylase subunits
RSDT_RS05015	COG1002	Type II restriction enzyme, methylase subunits
RSDT_RS05050	COG2217	Heavy metal translocating P-type atpase
RSDT_RS05060	COG0617	tRNA 3'-terminal CCA addition
RSDT_RS05075	COG1138	Cytochrome C-type biogenesis protein
RSDT_RS05090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RSDT_RS05110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RSDT_RS05130	COG0793	Belongs to the peptidase S41A family
RSDT_RS05135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RSDT_RS05140	COG0860	N-Acetylmuramoyl-L-alanine amidase
RSDT_RS05155	COG0151	Belongs to the GarS family
RSDT_RS05160	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RSDT_RS05165	COG1216	Glycosyl transferase, family 2
RSDT_RS05165	COG0463	Glycosyl transferase, family 2
RSDT_RS05185	COG0352	thiamine-phosphate diphosphorylase activity
RSDT_RS05195	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RSDT_RS05205	COG2920	part of a sulfur-relay system
RSDT_RS05225	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
RSDT_RS05255	COG4149	molybdate abc transporter
RSDT_RS05260	COG0725	ABC transporter, periplasmic molybdate-binding protein
RSDT_RS05270	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
RSDT_RS05275	COG1160	GTP binding
RSDT_RS05290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RSDT_RS05295	COG1324	tolerance protein
RSDT_RS05310	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RSDT_RS05320	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RSDT_RS05330	COG0556	nucleotide-excision repair
RSDT_RS05340	COG1113	amino acid transport
RSDT_RS05345	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RSDT_RS05350	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RSDT_RS05365	COG0495	leucyl-tRNA aminoacylation
RSDT_RS05370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RSDT_RS05375	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RSDT_RS05395	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RSDT_RS05400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RSDT_RS05405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RSDT_RS05415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RSDT_RS05425	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RSDT_RS05430	COG0730	response to heat
RSDT_RS05435	COG0402	S-adenosylhomocysteine deaminase activity
RSDT_RS05465	COG2084	Dehydrogenase
RSDT_RS05485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RSDT_RS05525	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RSDT_RS05535	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RSDT_RS05545	COG0651	ATP synthesis coupled electron transport
RSDT_RS05560	COG0651	ATP synthesis coupled electron transport
RSDT_RS05575	COG0156	8-amino-7-oxononanoate synthase activity
RSDT_RS05590	COG0438	transferase activity, transferring glycosyl groups
RSDT_RS05595	COG0367	asparagine synthase
RSDT_RS05605	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RSDT_RS05605	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RSDT_RS05640	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RSDT_RS05655	COG0335	large ribosomal subunit rRNA binding
RSDT_RS05660	COG0336	Belongs to the RNA methyltransferase TrmD family
RSDT_RS05660	COG4752	Belongs to the RNA methyltransferase TrmD family
RSDT_RS05670	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RSDT_RS05675	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RSDT_RS05695	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RSDT_RS05750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RSDT_RS05765	COG0051	transcription antitermination factor activity, RNA binding
RSDT_RS05770	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RSDT_RS05775	COG0088	Forms part of the polypeptide exit tunnel
RSDT_RS05780	COG0089	rRNA binding
RSDT_RS05785	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RSDT_RS05790	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RSDT_RS05795	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RSDT_RS05800	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RSDT_RS05805	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RSDT_RS05810	COG0255	Belongs to the universal ribosomal protein uL29 family
RSDT_RS05820	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RSDT_RS05825	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RSDT_RS05830	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RSDT_RS05835	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RSDT_RS05840	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RSDT_RS05845	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RSDT_RS05850	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RSDT_RS05855	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RSDT_RS05860	COG1841	ribosomal large subunit assembly
RSDT_RS05865	COG0200	Binds to the 23S rRNA
RSDT_RS05880	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RSDT_RS05885	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RSDT_RS05890	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RSDT_RS05895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RSDT_RS05900	COG0202	RNA polymerase activity
RSDT_RS05905	COG0203	ribosomal protein L17
RSDT_RS05910	COG0709	Synthesizes selenophosphate from selenide and ATP
RSDT_RS05935	COG0252	asparaginase activity
RSDT_RS05940	COG0228	four-way junction DNA binding
RSDT_RS05945	COG1837	Belongs to the UPF0109 family
RSDT_RS05955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RSDT_RS05995	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RSDT_RS06000	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RSDT_RS06005	COG0742	ribosomal rna small subunit methyltransferase
RSDT_RS06010	COG1611	Belongs to the LOG family
RSDT_RS06020	COG0543	2 iron, 2 sulfur cluster binding
RSDT_RS06025	COG0167	dihydroorotate dehydrogenase activity
RSDT_RS06040	COG0488	(ABC) transporter
RSDT_RS06045	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
RSDT_RS06060	COG1454	alcohol dehydrogenase
RSDT_RS06065	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RSDT_RS06070	COG0148	phosphopyruvate hydratase activity
RSDT_RS06075	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RSDT_RS06080	COG3852	Histidine kinase
RSDT_RS06085	COG0166	Belongs to the GPI family
RSDT_RS06105	COG0730	response to heat
RSDT_RS06145	COG1522	sequence-specific DNA binding
RSDT_RS06150	COG0535	radical SAM domain protein
RSDT_RS06155	COG0113	porphobilinogen synthase activity
RSDT_RS06160	COG0535	radical SAM domain protein
RSDT_RS06170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RSDT_RS06175	COG1192	Involved in chromosome partitioning
RSDT_RS06180	COG1475	DNA binding
RSDT_RS06185	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RSDT_RS06195	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RSDT_RS06205	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RSDT_RS06210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RSDT_RS06225	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RSDT_RS06235	COG1691	(AIR) carboxylase
RSDT_RS06255	COG0516	GMP reductase activity
RSDT_RS06255	COG0517	IMP dehydrogenase activity
RSDT_RS06265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RSDT_RS06270	COG0805	protein transport
RSDT_RS06285	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RSDT_RS06305	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RSDT_RS06310	COG0047	phosphoribosylformylglycinamidine synthase activity
RSDT_RS06315	COG0504	CTP synthase activity
RSDT_RS06325	COG0481	GTPase activity
RSDT_RS06360	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RSDT_RS06370	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RSDT_RS06395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RSDT_RS06400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RSDT_RS06405	COG0857	belongs to the CobB CobQ family
RSDT_RS06405	COG0280	phosphate acetyltransferase
RSDT_RS06415	COG0191	fructose-bisphosphate aldolase activity
RSDT_RS06425	COG0602	queuosine metabolic process
RSDT_RS06435	COG4822	anaerobic cobalamin biosynthetic process
RSDT_RS06465	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RSDT_RS06485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RSDT_RS06505	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RSDT_RS06510	COG0470	DNA polymerase III
RSDT_RS06530	COG1696	Membrane protein involved in D-alanine export
RSDT_RS06535	COG0776	regulation of translation
RSDT_RS06550	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RSDT_RS06555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RSDT_RS06560	COG0110	maltose O-acetyltransferase activity
RSDT_RS06565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RSDT_RS06590	COG1181	Belongs to the D-alanine--D-alanine ligase family
RSDT_RS06605	COG3005	denitrification pathway
RSDT_RS06610	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
RSDT_RS06640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RSDT_RS06655	COG1522	sequence-specific DNA binding
RSDT_RS06665	COG0724	RNA recognition motif
RSDT_RS06670	COG0305	Participates in initiation and elongation during chromosome replication
RSDT_RS06675	COG0359	binds to the 23S rRNA
RSDT_RS06680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RSDT_RS06685	COG0360	Binds together with S18 to 16S ribosomal RNA
RSDT_RS06700	COG2885	chlorophyll binding
RSDT_RS06705	COG0823	Involved in the tonB-independent uptake of proteins
RSDT_RS06715	COG0848	biopolymer transport protein
RSDT_RS06725	COG0330	HflC and HflK could
RSDT_RS06730	COG0330	HflC and HflK could
RSDT_RS06735	COG2022	thiamine diphosphate biosynthetic process
RSDT_RS06760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RSDT_RS06765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RSDT_RS06775	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RSDT_RS06780	COG0459	protein refolding
RSDT_RS06790	COG0210	DNA helicase
RSDT_RS06810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RSDT_RS06820	COG0750	zinc metalloprotease
RSDT_RS06830	COG4589	Belongs to the CDS family
RSDT_RS06845	COG3608	succinylglutamate desuccinylase aspartoacylase
RSDT_RS06845	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RSDT_RS06850	COG0463	Glycosyl transferase, family 2
RSDT_RS06855	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RSDT_RS06860	COG0217	transcriptional regulatory protein