locus-tag	class	description
CKBE_RS00020	COG0494	nUDIX hydrolase
CKBE_RS00025	COG0442	prolyl-tRNA aminoacylation
CKBE_RS00035	COG2885	chlorophyll binding
CKBE_RS00050	COG0786	glutamate:sodium symporter activity
CKBE_RS00070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKBE_RS00075	COG0741	lytic transglycosylase activity
CKBE_RS00075	COG1388	LysM domain
CKBE_RS00085	COG1132	(ABC) transporter
CKBE_RS00095	COG0307	riboflavin synthase, alpha
CKBE_RS00100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CKBE_RS00100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CKBE_RS00105	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CKBE_RS00110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CKBE_RS00115	COG0739	heme binding
CKBE_RS00120	COG0316	Belongs to the HesB IscA family
CKBE_RS00125	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CKBE_RS00130	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CKBE_RS00135	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CKBE_RS00140	COG0312	modulator of DNA gyrase
CKBE_RS00150	COG1042	CoA-binding domain protein
CKBE_RS00150	COG0045	succinate-CoA ligase (ADP-forming) activity
CKBE_RS00150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CKBE_RS00155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CKBE_RS00165	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CKBE_RS00170	COG2264	protein methyltransferase activity
CKBE_RS00175	COG0439	Biotin carboxylase
CKBE_RS00180	COG0511	ligase activity, forming carbon-carbon bonds
CKBE_RS00185	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CKBE_RS00190	COG0557	exoribonuclease II activity
CKBE_RS00205	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CKBE_RS00215	COG1678	Uncharacterized ACR, COG1678
CKBE_RS00220	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CKBE_RS00225	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CKBE_RS00235	COG0142	geranyltranstransferase activity
CKBE_RS00240	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CKBE_RS00245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CKBE_RS00250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CKBE_RS00255	COG0793	Belongs to the peptidase S41A family
CKBE_RS00260	COG0588	phosphoglycerate mutase activity
CKBE_RS00265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKBE_RS00270	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CKBE_RS00280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CKBE_RS00285	COG2226	methyltransferase
CKBE_RS00290	COG2204	response regulator
CKBE_RS00295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CKBE_RS00295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CKBE_RS00305	COG0242	peptide deformylase activity
CKBE_RS00310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CKBE_RS00315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CKBE_RS00320	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CKBE_RS00325	COG4988	ABC transporter
CKBE_RS00330	COG1294	oxidase, subunit
CKBE_RS00345	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CKBE_RS00370	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CKBE_RS00375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CKBE_RS00390	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CKBE_RS00395	COG0471	metal ion transport
CKBE_RS00400	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CKBE_RS00405	COG0772	Belongs to the SEDS family
CKBE_RS00410	COG0768	penicillin binding
CKBE_RS00420	COG1792	Involved in formation and maintenance of cell shape
CKBE_RS00425	COG1077	Cell shape determining protein MreB Mrl
CKBE_RS00435	COG0154	amidase activity
CKBE_RS00440	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CKBE_RS00445	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CKBE_RS00450	COG0708	Exodeoxyribonuclease III
CKBE_RS00460	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CKBE_RS00465	COG0513	Belongs to the DEAD box helicase family
CKBE_RS00475	COG0617	tRNA 3'-terminal CCA addition
CKBE_RS00490	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CKBE_RS00495	COG1560	Kdo2-lipid A biosynthetic process
CKBE_RS00500	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CKBE_RS00505	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CKBE_RS00510	COG0523	cobalamin synthesis protein
CKBE_RS00520	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CKBE_RS00525	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CKBE_RS00530	COG2921	Belongs to the UPF0250 family
CKBE_RS00535	COG1686	Belongs to the peptidase S11 family
CKBE_RS00540	COG2945	thiolester hydrolase activity
CKBE_RS00550	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CKBE_RS00560	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CKBE_RS00570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKBE_RS00580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CKBE_RS00590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CKBE_RS00595	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CKBE_RS00600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CKBE_RS00610	COG1965	Belongs to the frataxin family
CKBE_RS00615	COG0019	diaminopimelate decarboxylase activity
CKBE_RS00620	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CKBE_RS00630	COG0203	ribosomal protein L17
CKBE_RS00635	COG0202	RNA polymerase activity
CKBE_RS00640	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CKBE_RS00645	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CKBE_RS00650	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CKBE_RS00655	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CKBE_RS00660	COG0201	protein transport
CKBE_RS00665	COG0200	Binds to the 23S rRNA
CKBE_RS00670	COG1841	ribosomal large subunit assembly
CKBE_RS00675	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CKBE_RS00680	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CKBE_RS00685	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CKBE_RS00690	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CKBE_RS00695	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CKBE_RS00700	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CKBE_RS00705	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CKBE_RS00710	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CKBE_RS00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CKBE_RS00720	COG0255	Belongs to the universal ribosomal protein uL29 family
CKBE_RS00725	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CKBE_RS00730	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CKBE_RS00735	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CKBE_RS00740	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CKBE_RS00745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CKBE_RS00750	COG0089	rRNA binding
CKBE_RS00760	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CKBE_RS00765	COG0051	transcription antitermination factor activity, RNA binding
CKBE_RS00770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CKBE_RS00775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CKBE_RS00780	COG0049	tRNA binding
CKBE_RS00785	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CKBE_RS00790	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CKBE_RS00795	COG0085	RNA polymerase activity
CKBE_RS00800	COG0222	ribosome binding
CKBE_RS00805	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CKBE_RS00810	COG0081	regulation of translation
CKBE_RS00835	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CKBE_RS00855	COG0357	Ribosomal RNA small subunit methyltransferase G
CKBE_RS00860	COG0445	tRNA wobble uridine modification
CKBE_RS00865	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CKBE_RS00870	COG0706	membrane insertase activity
CKBE_RS00880	COG0594	ribonuclease P activity
CKBE_RS00885	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CKBE_RS00890	COG0592	DNA-directed DNA polymerase activity
CKBE_RS00910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CKBE_RS00915	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CKBE_RS00925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CKBE_RS00935	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CKBE_RS00955	COG0625	glutathione transferase activity
CKBE_RS00960	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CKBE_RS00970	COG0140	phosphoribosyl-ATP diphosphatase activity
CKBE_RS00980	COG0107	imidazoleglycerol-phosphate synthase activity
CKBE_RS00985	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CKBE_RS00995	COG0131	Imidazoleglycerol-phosphate dehydratase
CKBE_RS01000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CKBE_RS01005	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CKBE_RS01010	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CKBE_RS01015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CKBE_RS01025	COG1131	(ABC) transporter
CKBE_RS01035	COG2853	Lipoprotein
CKBE_RS01040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CKBE_RS01045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CKBE_RS01050	COG1127	ABC transporter
CKBE_RS01055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CKBE_RS01070	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CKBE_RS01080	COG0134	indole-3-glycerol-phosphate synthase activity
CKBE_RS01085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CKBE_RS01090	COG0512	Glutamine amidotransferase of anthranilate synthase
CKBE_RS01100	COG0546	phosphoglycolate phosphatase activity
CKBE_RS01105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CKBE_RS01115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CKBE_RS01135	COG0356	it plays a direct role in the translocation of protons across the membrane
CKBE_RS01145	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CKBE_RS01150	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CKBE_RS01155	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CKBE_RS01160	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CKBE_RS01165	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CKBE_RS01170	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CKBE_RS01175	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CKBE_RS01180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CKBE_RS01185	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CKBE_RS01200	COG2226	methyltransferase
CKBE_RS01215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CKBE_RS01220	COG0237	dephospho-CoA kinase activity
CKBE_RS01225	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CKBE_RS01235	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CKBE_RS01250	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CKBE_RS01255	COG2890	protein-(glutamine-N5) methyltransferase activity
CKBE_RS01260	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CKBE_RS01270	COG0288	reversible hydration of carbon dioxide
CKBE_RS01275	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CKBE_RS01280	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CKBE_RS01285	COG0129	dihydroxy-acid dehydratase activity
CKBE_RS01290	COG0628	permease
CKBE_RS01300	COG0326	Molecular chaperone. Has ATPase activity
CKBE_RS01305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CKBE_RS01315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CKBE_RS01315	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CKBE_RS01320	COG0489	protein tyrosine kinase activity
CKBE_RS01350	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CKBE_RS01355	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CKBE_RS01360	COG0277	FAD linked oxidase domain protein
CKBE_RS01365	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CKBE_RS01375	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CKBE_RS01395	COG0193	aminoacyl-tRNA hydrolase activity
CKBE_RS01405	COG0012	GTP binding
CKBE_RS01410	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CKBE_RS01415	COG0459	protein refolding
CKBE_RS01420	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CKBE_RS01430	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CKBE_RS01435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CKBE_RS01440	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CKBE_RS01445	COG2239	Acts as a magnesium transporter
CKBE_RS01465	COG0697	spore germination
CKBE_RS01485	COG4535	Mg2 and Co2 transporter CorC
CKBE_RS01490	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CKBE_RS01495	COG1702	phosphate starvation-inducible protein PhoH
CKBE_RS01500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CKBE_RS01505	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CKBE_RS01510	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CKBE_RS01515	COG1862	Preprotein translocase
CKBE_RS01520	COG0343	queuine tRNA-ribosyltransferase activity
CKBE_RS01530	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CKBE_RS01540	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CKBE_RS01545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CKBE_RS01550	COG0126	phosphoglycerate kinase activity
CKBE_RS01555	COG0306	phosphate transporter
CKBE_RS01565	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CKBE_RS01570	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CKBE_RS01580	COG0009	L-threonylcarbamoyladenylate synthase
CKBE_RS01585	COG4974	Belongs to the 'phage' integrase family
CKBE_RS01600	COG1074	ATP-dependent DNA helicase activity
CKBE_RS01610	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CKBE_RS01615	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CKBE_RS01625	COG0505	Belongs to the CarA family
CKBE_RS01630	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CKBE_RS01635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CKBE_RS01645	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CKBE_RS01650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CKBE_RS01655	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CKBE_RS01660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CKBE_RS01665	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CKBE_RS01685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CKBE_RS01690	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CKBE_RS01695	COG0668	transmembrane transport
CKBE_RS01700	COG0483	inositol monophosphate 1-phosphatase activity
CKBE_RS01705	COG1253	flavin adenine dinucleotide binding
CKBE_RS01715	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CKBE_RS01730	COG0215	cysteine-tRNA ligase activity
CKBE_RS01740	COG0825	malonyl-CoA metabolic process
CKBE_RS01750	COG0527	aspartate kinase activity
CKBE_RS01770	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CKBE_RS01805	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CKBE_RS01810	COG0799	negative regulation of ribosome biogenesis
CKBE_RS01815	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CKBE_RS01820	COG0151	Belongs to the GarS family
CKBE_RS01825	COG0217	transcriptional regulatory protein
CKBE_RS01835	COG0540	Belongs to the ATCase OTCase family
CKBE_RS01840	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CKBE_RS01850	COG0045	succinate-CoA ligase (ADP-forming) activity
CKBE_RS01855	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CKBE_RS01860	COG0181	hydroxymethylbilane synthase activity
CKBE_RS01880	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CKBE_RS01885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CKBE_RS01890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CKBE_RS01900	COG0066	3-isopropylmalate dehydratase activity
CKBE_RS01910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CKBE_RS01915	COG0101	tRNA pseudouridine synthase activity
CKBE_RS01920	COG0135	phosphoribosylanthranilate isomerase activity
CKBE_RS01930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CKBE_RS01935	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CKBE_RS01955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CKBE_RS01960	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CKBE_RS01965	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CKBE_RS01970	COG0196	riboflavin kinase activity
CKBE_RS01975	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CKBE_RS01980	COG0210	DNA helicase
CKBE_RS01985	COG2890	protein-(glutamine-N5) methyltransferase activity
CKBE_RS01995	COG2171	N-acyltransferase activity
CKBE_RS02010	COG1278	Cold shock
CKBE_RS02015	COG0544	peptidyl-prolyl cis-trans isomerase activity
CKBE_RS02020	COG0740	serine-type endopeptidase activity
CKBE_RS02025	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CKBE_RS02030	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CKBE_RS02040	COG0556	nucleotide-excision repair
CKBE_RS02045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CKBE_RS02055	COG1104	cysteine desulfurase activity
CKBE_RS02060	COG0822	iron-sulfur transferase activity
CKBE_RS02065	COG0316	Belongs to the HesB IscA family
CKBE_RS02070	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CKBE_RS02075	COG0443	Heat shock 70 kDa protein
CKBE_RS02080	COG0633	Ferredoxin
CKBE_RS02085	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CKBE_RS02090	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CKBE_RS02095	COG0602	queuosine metabolic process
CKBE_RS02100	COG0720	synthase
CKBE_RS02105	COG0590	tRNA wobble adenosine to inosine editing
CKBE_RS02115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKBE_RS02120	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CKBE_RS02125	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CKBE_RS02130	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CKBE_RS02155	COG0742	ribosomal rna small subunit methyltransferase
CKBE_RS02170	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CKBE_RS02175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CKBE_RS02180	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CKBE_RS02185	COG0284	orotidine-5'-phosphate decarboxylase activity
CKBE_RS02190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CKBE_RS02195	COG1758	RNA polymerase activity
CKBE_RS02200	COG0194	GDP metabolic process
CKBE_RS02205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CKBE_RS02220	COG0268	Binds directly to 16S ribosomal RNA
CKBE_RS02225	COG0728	peptidoglycan biosynthetic process
CKBE_RS02230	COG0563	adenylate kinase activity
CKBE_RS02235	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CKBE_RS02240	COG1663	tetraacyldisaccharide 4'-kinase activity
CKBE_RS02250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CKBE_RS02255	COG1278	Cold shock
CKBE_RS02265	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CKBE_RS02270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CKBE_RS02275	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CKBE_RS02280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CKBE_RS02280	COG0072	phenylalanine-tRNA ligase activity
CKBE_RS02285	COG0776	regulation of translation
CKBE_RS02300	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CKBE_RS02305	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CKBE_RS02310	COG0508	dehydrogenase complex catalyzes the overall conversion of
CKBE_RS02315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CKBE_RS02320	COG0668	transmembrane transport
CKBE_RS02325	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CKBE_RS02325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CKBE_RS02330	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CKBE_RS02345	COG1136	(ABC) transporter
CKBE_RS02350	COG0084	hydrolase, TatD family'
CKBE_RS02355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CKBE_RS02355	COG0047	phosphoribosylformylglycinamidine synthase activity
CKBE_RS02360	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CKBE_RS02365	COG0285	dihydrofolate synthase activity
CKBE_RS02370	COG1286	toxin biosynthetic process
CKBE_RS02380	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CKBE_RS02390	COG0024	Methionine aminopeptidase
CKBE_RS02395	COG0052	Belongs to the universal ribosomal protein uS2 family
CKBE_RS02400	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CKBE_RS02405	COG0528	UMP kinase activity
CKBE_RS02410	COG0233	cytoplasmic translational termination
CKBE_RS02415	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CKBE_RS02420	COG4589	Belongs to the CDS family
CKBE_RS02425	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CKBE_RS02430	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CKBE_RS02440	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CKBE_RS02445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CKBE_RS02455	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CKBE_RS02460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CKBE_RS02475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CKBE_RS02495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CKBE_RS02500	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CKBE_RS02510	COG0084	hydrolase, TatD family'
CKBE_RS02525	COG0519	Catalyzes the synthesis of GMP from XMP
CKBE_RS02525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CKBE_RS02530	COG0516	GMP reductase activity
CKBE_RS02530	COG0517	IMP dehydrogenase activity
CKBE_RS02540	COG1966	Carbon starvation protein
CKBE_RS02545	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CKBE_RS02550	COG0251	oxidation-reduction process
CKBE_RS02560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CKBE_RS02565	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CKBE_RS02570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CKBE_RS02580	COG0776	regulation of translation
CKBE_RS02585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CKBE_RS02590	COG0557	exoribonuclease II activity
CKBE_RS02605	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CKBE_RS02610	COG0482	sulfurtransferase activity
CKBE_RS02615	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CKBE_RS02620	COG0312	modulator of DNA gyrase
CKBE_RS02625	COG0308	aminopeptidase N
CKBE_RS02630	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CKBE_RS02645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CKBE_RS02650	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CKBE_RS02655	COG0305	Participates in initiation and elongation during chromosome replication
CKBE_RS02660	COG0359	binds to the 23S rRNA
CKBE_RS02665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CKBE_RS02675	COG0360	Binds together with S18 to 16S ribosomal RNA
CKBE_RS02680	COG1469	GTP cyclohydrolase I activity
CKBE_RS02685	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CKBE_RS02690	COG0142	geranyltranstransferase activity
CKBE_RS02695	COG1722	exodeoxyribonuclease VII activity
CKBE_RS02710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CKBE_RS02720	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CKBE_RS02725	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CKBE_RS02730	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CKBE_RS02735	COG0330	HflC and HflK could
CKBE_RS02740	COG0330	HflC and HflK could
CKBE_RS02745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CKBE_RS02750	COG1923	regulation of RNA biosynthetic process
CKBE_RS02755	COG1160	GTP binding
CKBE_RS02765	COG0124	histidyl-tRNA synthetase
CKBE_RS02775	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CKBE_RS02780	COG0105	UTP biosynthetic process
CKBE_RS02790	COG0336	Belongs to the RNA methyltransferase TrmD family
CKBE_RS02795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CKBE_RS02800	COG0228	four-way junction DNA binding
CKBE_RS02805	COG0425	Belongs to the sulfur carrier protein TusA family
CKBE_RS02810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CKBE_RS02820	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CKBE_RS02825	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CKBE_RS02840	COG1217	gtp-binding protein TYPA
CKBE_RS02845	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CKBE_RS02850	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CKBE_RS02860	COG0195	Participates in both transcription termination and antitermination
CKBE_RS02865	COG0779	Required for maturation of 30S ribosomal subunits
CKBE_RS02880	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CKBE_RS02885	COG0254	rRNA binding
CKBE_RS02890	COG0534	Mate efflux family protein
CKBE_RS02895	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CKBE_RS02900	COG1162	GTPase activity
CKBE_RS02905	COG0335	large ribosomal subunit rRNA binding
CKBE_RS02915	COG2086	electron transfer activity
CKBE_RS02920	COG0123	including yeast histone deacetylase and acetoin utilization protein
CKBE_RS02925	COG0776	regulation of translation
CKBE_RS02940	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CKBE_RS02945	COG0287	Prephenate dehydrogenase
CKBE_RS02950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CKBE_RS02955	COG1605	Chorismate mutase
CKBE_RS02955	COG0077	Prephenate dehydratase
CKBE_RS02960	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CKBE_RS02970	COG2885	chlorophyll binding
CKBE_RS02975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CKBE_RS02985	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CKBE_RS02990	COG0180	Tryptophanyl-tRNA synthetase
CKBE_RS02995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CKBE_RS03000	COG0508	dehydrogenase complex catalyzes the overall conversion of
CKBE_RS03005	COG0567	Dehydrogenase, E1 component
CKBE_RS03020	COG0148	phosphopyruvate hydratase activity
CKBE_RS03025	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CKBE_RS03030	COG0504	CTP synthase activity
CKBE_RS03040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CKBE_RS03045	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CKBE_RS03050	COG0791	NLP P60 protein
CKBE_RS03060	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CKBE_RS03075	COG1381	Involved in DNA repair and RecF pathway recombination
CKBE_RS03080	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CKBE_RS03085	COG0571	ribonuclease III activity
CKBE_RS03090	COG0681	Belongs to the peptidase S26 family
CKBE_RS03095	COG0481	GTPase activity
CKBE_RS03100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKBE_RS03105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CKBE_RS03110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CKBE_RS03115	COG1028	Short-chain dehydrogenase reductase Sdr
CKBE_RS03125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKBE_RS03135	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CKBE_RS03140	COG0424	maF-like protein
CKBE_RS03150	COG0564	pseudouridine synthase activity
CKBE_RS03155	COG1530	ribonuclease E activity
CKBE_RS03160	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CKBE_RS03165	COG0159	tryptophan synthase activity
CKBE_RS03170	COG0133	tryptophan synthase activity
CKBE_RS03175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CKBE_RS03180	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CKBE_RS03185	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CKBE_RS03190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CKBE_RS03195	COG2878	Part of a membrane complex involved in electron transport
CKBE_RS03200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CKBE_RS03205	COG2917	probably involved in intracellular septation
CKBE_RS03215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CKBE_RS03220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CKBE_RS03230	COG1573	uracil-dna glycosylase
CKBE_RS03235	COG1214	PFAM Peptidase M22, glycoprotease
CKBE_RS03240	COG0450	alkyl hydroperoxide reductase
CKBE_RS03245	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CKBE_RS03250	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CKBE_RS03255	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CKBE_RS03260	COG1007	ATP synthesis coupled electron transport
CKBE_RS03275	COG0713	ATP synthesis coupled electron transport
CKBE_RS03285	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKBE_RS03290	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CKBE_RS03295	COG1034	ATP synthesis coupled electron transport
CKBE_RS03305	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CKBE_RS03310	COG0649	NAD binding
CKBE_RS03315	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKBE_RS03320	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKBE_RS03325	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKBE_RS03330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CKBE_RS03340	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CKBE_RS03345	COG0149	triose-phosphate isomerase activity
CKBE_RS03350	COG3321	synthase
CKBE_RS03350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CKBE_RS03350	COG4221	oxidoreductase activity
CKBE_RS03350	COG0604	alcohol dehydrogenase
CKBE_RS03365	COG1185	polyribonucleotide nucleotidyltransferase activity
CKBE_RS03370	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CKBE_RS03375	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CKBE_RS03385	COG0028	Belongs to the TPP enzyme family
CKBE_RS03390	COG3022	response to hydroperoxide
CKBE_RS03400	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CKBE_RS03405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CKBE_RS03410	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CKBE_RS03415	COG1674	ftsk spoiiie
CKBE_RS03420	COG0492	ferredoxin-NADP+ reductase activity
CKBE_RS03430	COG2076	Multidrug Resistance protein
CKBE_RS03440	COG0484	heat shock protein binding
CKBE_RS03445	COG0443	Heat shock 70 kDa protein
CKBE_RS03450	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CKBE_RS03455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CKBE_RS03460	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CKBE_RS03465	COG0497	DNA recombination
CKBE_RS03470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CKBE_RS03505	COG0513	Belongs to the DEAD box helicase family
CKBE_RS03515	COG0006	proline dipeptidase activity
CKBE_RS03520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CKBE_RS03535	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CKBE_RS03540	COG0632	four-way junction helicase activity
CKBE_RS03545	COG2255	four-way junction helicase activity
CKBE_RS03550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CKBE_RS03555	COG0850	regulation of cytokinetic process
CKBE_RS03560	COG2894	cell division
CKBE_RS03565	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CKBE_RS03570	COG0488	(ABC) transporter
CKBE_RS03580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CKBE_RS03585	COG0259	pyridoxamine-phosphate oxidase activity
CKBE_RS03590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CKBE_RS03595	COG0802	atpase or kinase
CKBE_RS03605	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CKBE_RS03610	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CKBE_RS03615	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CKBE_RS03635	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CKBE_RS03640	COG0752	glycyl-tRNA synthetase alpha subunit
CKBE_RS03650	COG0204	Acyl-transferase
CKBE_RS03655	COG0653	protein targeting
CKBE_RS03665	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CKBE_RS03670	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CKBE_RS03675	COG1181	Belongs to the D-alanine--D-alanine ligase family
CKBE_RS03680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CKBE_RS03685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CKBE_RS03690	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CKBE_RS03695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CKBE_RS03700	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CKBE_RS03705	COG0275	rRNA processing
CKBE_RS03710	COG0488	(ABC) transporter
CKBE_RS03715	COG0418	dihydroorotase activity
CKBE_RS03755	COG1132	(ABC) transporter
CKBE_RS03760	COG0587	DNA-directed DNA polymerase activity
CKBE_RS03765	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CKBE_RS03765	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CKBE_RS03770	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CKBE_RS03775	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CKBE_RS03785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKBE_RS03800	COG0542	response to heat
CKBE_RS03805	COG2951	lytic endotransglycosylase activity
CKBE_RS03820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CKBE_RS03830	COG0736	holo-[acyl-carrier-protein] synthase activity
CKBE_RS03835	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CKBE_RS03840	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CKBE_RS03845	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CKBE_RS03850	COG0495	leucyl-tRNA aminoacylation