locus-tag	class	description
ST1E_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ST1E_RS00010	COG0592	DNA-directed DNA polymerase activity
ST1E_RS00025	COG0551	DNA topoisomerase type I activity
ST1E_RS00025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ST1E_RS00030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ST1E_RS00035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ST1E_RS00040	COG0018	arginyl-trna synthetase
ST1E_RS00045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ST1E_RS00055	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ST1E_RS00075	COG0625	glutathione transferase activity
ST1E_RS00080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ST1E_RS00090	COG0140	phosphoribosyl-ATP diphosphatase activity
ST1E_RS00100	COG0107	imidazoleglycerol-phosphate synthase activity
ST1E_RS00105	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ST1E_RS00110	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ST1E_RS00115	COG0131	Imidazoleglycerol-phosphate dehydratase
ST1E_RS00120	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ST1E_RS00125	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ST1E_RS00130	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ST1E_RS00135	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ST1E_RS00145	COG1131	(ABC) transporter
ST1E_RS00155	COG2853	Lipoprotein
ST1E_RS00160	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ST1E_RS00170	COG1127	ABC transporter
ST1E_RS00175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ST1E_RS00190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ST1E_RS00205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ST1E_RS00210	COG0512	Glutamine amidotransferase of anthranilate synthase
ST1E_RS00220	COG0546	phosphoglycolate phosphatase activity
ST1E_RS00225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ST1E_RS00230	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ST1E_RS00255	COG0356	it plays a direct role in the translocation of protons across the membrane
ST1E_RS00265	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ST1E_RS00270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ST1E_RS00275	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ST1E_RS00280	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ST1E_RS00290	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ST1E_RS00295	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ST1E_RS00300	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ST1E_RS00305	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ST1E_RS00320	COG2226	methyltransferase
ST1E_RS00335	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ST1E_RS00340	COG0237	dephospho-CoA kinase activity
ST1E_RS00345	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ST1E_RS00355	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ST1E_RS00375	COG2890	protein-(glutamine-N5) methyltransferase activity
ST1E_RS00380	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ST1E_RS00390	COG0288	reversible hydration of carbon dioxide
ST1E_RS00395	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ST1E_RS00400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ST1E_RS00405	COG0129	dihydroxy-acid dehydratase activity
ST1E_RS00410	COG0628	permease
ST1E_RS00420	COG0326	Molecular chaperone. Has ATPase activity
ST1E_RS00425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ST1E_RS00435	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ST1E_RS00435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ST1E_RS00440	COG0489	protein tyrosine kinase activity
ST1E_RS00455	COG0717	Belongs to the dCTP deaminase family
ST1E_RS00470	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ST1E_RS00475	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ST1E_RS00480	COG0277	FAD linked oxidase domain protein
ST1E_RS00485	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ST1E_RS00495	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ST1E_RS00525	COG0012	GTP binding
ST1E_RS00530	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ST1E_RS00535	COG0459	protein refolding
ST1E_RS00540	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ST1E_RS00550	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ST1E_RS00555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ST1E_RS00560	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ST1E_RS00565	COG2239	Acts as a magnesium transporter
ST1E_RS00570	COG1607	acyl-coa hydrolase
ST1E_RS00585	COG0697	spore germination
ST1E_RS00605	COG4535	Mg2 and Co2 transporter CorC
ST1E_RS00610	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ST1E_RS00615	COG1702	phosphate starvation-inducible protein PhoH
ST1E_RS00620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ST1E_RS00625	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ST1E_RS00630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ST1E_RS00635	COG1862	Preprotein translocase
ST1E_RS00640	COG0343	queuine tRNA-ribosyltransferase activity
ST1E_RS00650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ST1E_RS00655	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ST1E_RS00660	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ST1E_RS00665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ST1E_RS00670	COG0126	phosphoglycerate kinase activity
ST1E_RS00675	COG0306	phosphate transporter
ST1E_RS00685	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ST1E_RS00690	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ST1E_RS00695	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ST1E_RS00700	COG0009	L-threonylcarbamoyladenylate synthase
ST1E_RS00705	COG4974	Belongs to the 'phage' integrase family
ST1E_RS00720	COG1074	ATP-dependent DNA helicase activity
ST1E_RS00725	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ST1E_RS00735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ST1E_RS00745	COG0505	Belongs to the CarA family
ST1E_RS00750	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ST1E_RS00755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ST1E_RS00765	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ST1E_RS00770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ST1E_RS00775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ST1E_RS00780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ST1E_RS00785	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ST1E_RS00805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ST1E_RS00810	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ST1E_RS00815	COG0668	transmembrane transport
ST1E_RS00825	COG1253	flavin adenine dinucleotide binding
ST1E_RS00830	COG1968	undecaprenyl-diphosphatase activity
ST1E_RS00835	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ST1E_RS00850	COG0215	cysteine-tRNA ligase activity
ST1E_RS00860	COG0825	malonyl-CoA metabolic process
ST1E_RS00870	COG0527	aspartate kinase activity
ST1E_RS00890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ST1E_RS00930	COG0495	leucyl-tRNA aminoacylation
ST1E_RS00940	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ST1E_RS00945	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ST1E_RS00950	COG0736	holo-[acyl-carrier-protein] synthase activity
ST1E_RS00960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ST1E_RS00975	COG2951	lytic endotransglycosylase activity
ST1E_RS00980	COG0542	response to heat
ST1E_RS00985	COG1562	ergosterol biosynthetic process
ST1E_RS00995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ST1E_RS01000	COG1322	Protein conserved in bacteria
ST1E_RS01005	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ST1E_RS01010	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ST1E_RS01015	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ST1E_RS01015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ST1E_RS01020	COG0587	DNA-directed DNA polymerase activity
ST1E_RS01025	COG1132	(ABC) transporter
ST1E_RS01030	COG1530	ribonuclease E activity
ST1E_RS01060	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ST1E_RS01070	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ST1E_RS01075	COG0151	Belongs to the GarS family
ST1E_RS01080	COG0217	transcriptional regulatory protein
ST1E_RS01090	COG0540	Belongs to the ATCase OTCase family
ST1E_RS01095	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ST1E_RS01100	COG2137	regulation of response to DNA damage stimulus
ST1E_RS01105	COG0045	succinate-CoA ligase (ADP-forming) activity
ST1E_RS01110	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ST1E_RS01115	COG0181	hydroxymethylbilane synthase activity
ST1E_RS01135	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ST1E_RS01140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ST1E_RS01145	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ST1E_RS01165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ST1E_RS01170	COG0101	tRNA pseudouridine synthase activity
ST1E_RS01185	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ST1E_RS01190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ST1E_RS01200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ST1E_RS01210	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ST1E_RS01215	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ST1E_RS01220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ST1E_RS01225	COG0196	riboflavin kinase activity
ST1E_RS01230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ST1E_RS01235	COG0210	DNA helicase
ST1E_RS01240	COG2890	protein-(glutamine-N5) methyltransferase activity
ST1E_RS01250	COG2171	N-acyltransferase activity
ST1E_RS01255	COG0436	Aminotransferase
ST1E_RS01265	COG1278	Cold shock
ST1E_RS01270	COG0544	peptidyl-prolyl cis-trans isomerase activity
ST1E_RS01275	COG0740	serine-type endopeptidase activity
ST1E_RS01280	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ST1E_RS01285	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ST1E_RS01295	COG0556	nucleotide-excision repair
ST1E_RS01300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ST1E_RS01310	COG1104	cysteine desulfurase activity
ST1E_RS01315	COG0822	iron-sulfur transferase activity
ST1E_RS01320	COG0316	Belongs to the HesB IscA family
ST1E_RS01325	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ST1E_RS01335	COG0633	Ferredoxin
ST1E_RS01340	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ST1E_RS01345	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ST1E_RS01350	COG0602	queuosine metabolic process
ST1E_RS01355	COG0720	synthase
ST1E_RS01360	COG0590	tRNA wobble adenosine to inosine editing
ST1E_RS01370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ST1E_RS01375	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ST1E_RS01380	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ST1E_RS01400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ST1E_RS01410	COG0742	ribosomal rna small subunit methyltransferase
ST1E_RS01425	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ST1E_RS01430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ST1E_RS01435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ST1E_RS01440	COG0284	orotidine-5'-phosphate decarboxylase activity
ST1E_RS01445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ST1E_RS01450	COG1758	RNA polymerase activity
ST1E_RS01455	COG0194	GDP metabolic process
ST1E_RS01460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ST1E_RS01475	COG0268	Binds directly to 16S ribosomal RNA
ST1E_RS01480	COG0728	peptidoglycan biosynthetic process
ST1E_RS01485	COG0563	adenylate kinase activity
ST1E_RS01495	COG1663	tetraacyldisaccharide 4'-kinase activity
ST1E_RS01505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ST1E_RS01510	COG1278	Cold shock
ST1E_RS01520	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ST1E_RS01525	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ST1E_RS01530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ST1E_RS01535	COG0072	phenylalanine-tRNA ligase activity
ST1E_RS01535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ST1E_RS01540	COG0776	regulation of translation
ST1E_RS01555	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ST1E_RS01560	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ST1E_RS01565	COG0508	dehydrogenase complex catalyzes the overall conversion of
ST1E_RS01570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ST1E_RS01575	COG0668	transmembrane transport
ST1E_RS01580	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ST1E_RS01580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ST1E_RS01585	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ST1E_RS01600	COG1136	(ABC) transporter
ST1E_RS01605	COG0084	hydrolase, TatD family'
ST1E_RS01610	COG0047	phosphoribosylformylglycinamidine synthase activity
ST1E_RS01610	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ST1E_RS01615	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ST1E_RS01620	COG0285	dihydrofolate synthase activity
ST1E_RS01635	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ST1E_RS01645	COG0024	Methionine aminopeptidase
ST1E_RS01650	COG0052	Belongs to the universal ribosomal protein uS2 family
ST1E_RS01655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ST1E_RS01660	COG0528	UMP kinase activity
ST1E_RS01665	COG0233	cytoplasmic translational termination
ST1E_RS01670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ST1E_RS01675	COG0575	Belongs to the CDS family
ST1E_RS01680	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ST1E_RS01685	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ST1E_RS01695	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ST1E_RS01700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ST1E_RS01705	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ST1E_RS01710	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ST1E_RS01715	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ST1E_RS01730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ST1E_RS01735	COG2867	negative regulation of translational initiation
ST1E_RS01740	COG2914	Belongs to the UPF0125 (RnfH) family
ST1E_RS01750	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ST1E_RS01755	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ST1E_RS01765	COG0084	hydrolase, TatD family'
ST1E_RS01770	COG0095	Lipoate-protein ligase
ST1E_RS01780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ST1E_RS01780	COG0519	Catalyzes the synthesis of GMP from XMP
ST1E_RS01785	COG0516	GMP reductase activity
ST1E_RS01785	COG0517	IMP dehydrogenase activity
ST1E_RS01795	COG1966	Carbon starvation protein
ST1E_RS01800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ST1E_RS01815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ST1E_RS01820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ST1E_RS01825	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ST1E_RS01835	COG0776	regulation of translation
ST1E_RS01840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ST1E_RS01845	COG0557	exoribonuclease II activity
ST1E_RS01860	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ST1E_RS01865	COG0482	sulfurtransferase activity
ST1E_RS01870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ST1E_RS01875	COG0312	modulator of DNA gyrase
ST1E_RS01880	COG0308	aminopeptidase N
ST1E_RS01885	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ST1E_RS01900	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ST1E_RS01905	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ST1E_RS01910	COG0305	Participates in initiation and elongation during chromosome replication
ST1E_RS01915	COG0359	binds to the 23S rRNA
ST1E_RS01920	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ST1E_RS01930	COG0360	Binds together with S18 to 16S ribosomal RNA
ST1E_RS01935	COG1469	GTP cyclohydrolase I activity
ST1E_RS01940	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ST1E_RS01945	COG0142	geranyltranstransferase activity
ST1E_RS01950	COG1722	exodeoxyribonuclease VII activity
ST1E_RS01965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ST1E_RS01975	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ST1E_RS01980	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ST1E_RS01985	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ST1E_RS01990	COG0330	HflC and HflK could
ST1E_RS01995	COG0330	HflC and HflK could
ST1E_RS02000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ST1E_RS02005	COG1923	regulation of RNA biosynthetic process
ST1E_RS02010	COG1160	GTP binding
ST1E_RS02020	COG0124	histidyl-tRNA synthetase
ST1E_RS02030	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ST1E_RS02035	COG0105	UTP biosynthetic process
ST1E_RS02045	COG0336	Belongs to the RNA methyltransferase TrmD family
ST1E_RS02050	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ST1E_RS02055	COG0228	four-way junction DNA binding
ST1E_RS02060	COG0425	Belongs to the sulfur carrier protein TusA family
ST1E_RS02065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ST1E_RS02075	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ST1E_RS02080	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ST1E_RS02090	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ST1E_RS02090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ST1E_RS02095	COG1217	gtp-binding protein TYPA
ST1E_RS02100	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ST1E_RS02105	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ST1E_RS02115	COG0195	Participates in both transcription termination and antitermination
ST1E_RS02115	COG2251	uridine kinase activity
ST1E_RS02120	COG0779	Required for maturation of 30S ribosomal subunits
ST1E_RS02135	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ST1E_RS02140	COG0254	rRNA binding
ST1E_RS02145	COG0534	Mate efflux family protein
ST1E_RS02150	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ST1E_RS02155	COG1162	GTPase activity
ST1E_RS02160	COG0335	large ribosomal subunit rRNA binding
ST1E_RS02170	COG2086	electron transfer activity
ST1E_RS02175	COG0123	including yeast histone deacetylase and acetoin utilization protein
ST1E_RS02180	COG0776	regulation of translation
ST1E_RS02195	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ST1E_RS02200	COG0287	Prephenate dehydrogenase
ST1E_RS02205	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ST1E_RS02210	COG0077	Prephenate dehydratase
ST1E_RS02210	COG1605	Chorismate mutase
ST1E_RS02215	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ST1E_RS02225	COG2885	chlorophyll binding
ST1E_RS02230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ST1E_RS02240	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ST1E_RS02250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ST1E_RS02255	COG0508	dehydrogenase complex catalyzes the overall conversion of
ST1E_RS02260	COG0567	Dehydrogenase, E1 component
ST1E_RS02265	COG0281	malic enzyme
ST1E_RS02265	COG0280	phosphate acetyltransferase
ST1E_RS02275	COG0148	phosphopyruvate hydratase activity
ST1E_RS02280	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ST1E_RS02285	COG0504	CTP synthase activity
ST1E_RS02295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ST1E_RS02300	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ST1E_RS02305	COG0791	NLP P60 protein
ST1E_RS02315	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ST1E_RS02325	COG0670	Belongs to the BI1 family
ST1E_RS02330	COG1381	Involved in DNA repair and RecF pathway recombination
ST1E_RS02335	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ST1E_RS02340	COG0571	ribonuclease III activity
ST1E_RS02345	COG0681	Belongs to the peptidase S26 family
ST1E_RS02350	COG0481	GTPase activity
ST1E_RS02355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ST1E_RS02360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ST1E_RS02365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ST1E_RS02370	COG1028	Short-chain dehydrogenase reductase Sdr
ST1E_RS02375	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ST1E_RS02380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ST1E_RS02390	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ST1E_RS02395	COG0424	maF-like protein
ST1E_RS02405	COG0564	pseudouridine synthase activity
ST1E_RS02410	COG1530	ribonuclease E activity
ST1E_RS02415	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ST1E_RS02420	COG0159	tryptophan synthase activity
ST1E_RS02425	COG0133	tryptophan synthase activity
ST1E_RS02430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ST1E_RS02440	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ST1E_RS02445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ST1E_RS02450	COG2878	Part of a membrane complex involved in electron transport
ST1E_RS02455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ST1E_RS02460	COG2917	probably involved in intracellular septation
ST1E_RS02470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ST1E_RS02475	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ST1E_RS02485	COG0477	Major facilitator Superfamily
ST1E_RS02495	COG1214	PFAM Peptidase M22, glycoprotease
ST1E_RS02500	COG0450	alkyl hydroperoxide reductase
ST1E_RS02505	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ST1E_RS02510	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ST1E_RS02515	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ST1E_RS02520	COG1007	ATP synthesis coupled electron transport
ST1E_RS02535	COG0713	ATP synthesis coupled electron transport
ST1E_RS02545	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ST1E_RS02550	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ST1E_RS02555	COG1034	ATP synthesis coupled electron transport
ST1E_RS02565	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ST1E_RS02570	COG0649	NAD binding
ST1E_RS02575	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ST1E_RS02580	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ST1E_RS02590	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ST1E_RS02600	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ST1E_RS02605	COG0149	triose-phosphate isomerase activity
ST1E_RS02610	COG0604	alcohol dehydrogenase
ST1E_RS02610	COG1028	Short-chain dehydrogenase reductase Sdr
ST1E_RS02610	COG3321	synthase
ST1E_RS02625	COG1185	polyribonucleotide nucleotidyltransferase activity
ST1E_RS02630	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ST1E_RS02635	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ST1E_RS02640	COG0440	acetolactate synthase activity
ST1E_RS02645	COG0028	Belongs to the TPP enzyme family
ST1E_RS02650	COG3022	response to hydroperoxide
ST1E_RS02660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ST1E_RS02665	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ST1E_RS02670	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ST1E_RS02675	COG1674	ftsk spoiiie
ST1E_RS02680	COG0492	ferredoxin-NADP+ reductase activity
ST1E_RS02690	COG2076	Multidrug Resistance protein
ST1E_RS02705	COG0484	heat shock protein binding
ST1E_RS02710	COG0443	Heat shock 70 kDa protein
ST1E_RS02715	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ST1E_RS02720	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ST1E_RS02730	COG0497	DNA recombination
ST1E_RS02745	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ST1E_RS02770	COG0513	Belongs to the DEAD box helicase family
ST1E_RS02780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ST1E_RS02795	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ST1E_RS02805	COG2255	four-way junction helicase activity
ST1E_RS02810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ST1E_RS02815	COG0850	regulation of cytokinetic process
ST1E_RS02820	COG2894	cell division
ST1E_RS02825	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ST1E_RS02830	COG0488	(ABC) transporter
ST1E_RS02840	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ST1E_RS02845	COG0259	pyridoxamine-phosphate oxidase activity
ST1E_RS02850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ST1E_RS02855	COG0802	atpase or kinase
ST1E_RS02860	COG0860	N-Acetylmuramoyl-L-alanine amidase
ST1E_RS02865	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ST1E_RS02870	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ST1E_RS02875	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ST1E_RS02890	COG0617	tRNA 3'-terminal CCA addition
ST1E_RS02895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ST1E_RS02900	COG0752	glycyl-tRNA synthetase alpha subunit
ST1E_RS02910	COG0204	Acyl-transferase
ST1E_RS02915	COG0653	protein targeting
ST1E_RS02925	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ST1E_RS02930	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ST1E_RS02935	COG1181	Belongs to the D-alanine--D-alanine ligase family
ST1E_RS02940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ST1E_RS02950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ST1E_RS02955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ST1E_RS02960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ST1E_RS02965	COG0275	rRNA processing
ST1E_RS02970	COG0488	(ABC) transporter
ST1E_RS02975	COG0418	dihydroorotase activity
ST1E_RS03025	COG0494	nUDIX hydrolase
ST1E_RS03030	COG0442	prolyl-tRNA aminoacylation
ST1E_RS03035	COG0823	Involved in the tonB-independent uptake of proteins
ST1E_RS03040	COG2885	chlorophyll binding
ST1E_RS03050	COG0596	Alpha beta hydrolase
ST1E_RS03055	COG0786	glutamate:sodium symporter activity
ST1E_RS03065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ST1E_RS03070	COG0328	RNA-DNA hybrid ribonuclease activity
ST1E_RS03075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ST1E_RS03080	COG0741	lytic transglycosylase activity
ST1E_RS03080	COG1388	LysM domain
ST1E_RS03090	COG1132	(ABC) transporter
ST1E_RS03100	COG0307	riboflavin synthase, alpha
ST1E_RS03105	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ST1E_RS03105	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ST1E_RS03110	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ST1E_RS03115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ST1E_RS03120	COG0739	heme binding
ST1E_RS03125	COG0316	Belongs to the HesB IscA family
ST1E_RS03130	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ST1E_RS03135	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ST1E_RS03140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ST1E_RS03145	COG0312	modulator of DNA gyrase
ST1E_RS03155	COG0045	succinate-CoA ligase (ADP-forming) activity
ST1E_RS03155	COG1042	CoA-binding domain protein
ST1E_RS03155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ST1E_RS03160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ST1E_RS03170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ST1E_RS03175	COG2264	protein methyltransferase activity
ST1E_RS03180	COG0439	Biotin carboxylase
ST1E_RS03185	COG0511	ligase activity, forming carbon-carbon bonds
ST1E_RS03190	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ST1E_RS03195	COG0557	exoribonuclease II activity
ST1E_RS03200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ST1E_RS03210	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ST1E_RS03215	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ST1E_RS03220	COG1678	Uncharacterized ACR, COG1678
ST1E_RS03225	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ST1E_RS03230	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ST1E_RS03240	COG0142	geranyltranstransferase activity
ST1E_RS03245	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ST1E_RS03250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ST1E_RS03255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ST1E_RS03260	COG0793	Belongs to the peptidase S41A family
ST1E_RS03265	COG0588	phosphoglycerate mutase activity
ST1E_RS03270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ST1E_RS03275	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ST1E_RS03285	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ST1E_RS03290	COG2226	methyltransferase
ST1E_RS03295	COG2204	response regulator
ST1E_RS03300	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ST1E_RS03300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ST1E_RS03310	COG0242	peptide deformylase activity
ST1E_RS03315	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ST1E_RS03320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ST1E_RS03325	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ST1E_RS03330	COG4988	ABC transporter
ST1E_RS03335	COG1294	oxidase, subunit
ST1E_RS03350	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ST1E_RS03365	COG1137	ATPase activity
ST1E_RS03375	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ST1E_RS03380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ST1E_RS03390	COG2823	Periplasmic or secreted lipoprotein
ST1E_RS03395	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ST1E_RS03400	COG0471	metal ion transport
ST1E_RS03405	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ST1E_RS03410	COG0772	Belongs to the SEDS family
ST1E_RS03415	COG0768	penicillin binding
ST1E_RS03425	COG1792	Involved in formation and maintenance of cell shape
ST1E_RS03430	COG1077	Cell shape determining protein MreB Mrl
ST1E_RS03435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ST1E_RS03440	COG0154	amidase activity
ST1E_RS03445	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ST1E_RS03450	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ST1E_RS03455	COG0708	Exodeoxyribonuclease III
ST1E_RS03465	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ST1E_RS03495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ST1E_RS03500	COG1560	Kdo2-lipid A biosynthetic process
ST1E_RS03505	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ST1E_RS03510	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ST1E_RS03515	COG0523	cobalamin synthesis protein
ST1E_RS03525	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ST1E_RS03530	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ST1E_RS03535	COG2921	Belongs to the UPF0250 family
ST1E_RS03540	COG1686	Belongs to the peptidase S11 family
ST1E_RS03545	COG2945	thiolester hydrolase activity
ST1E_RS03555	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ST1E_RS03565	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ST1E_RS03585	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ST1E_RS03600	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ST1E_RS03605	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ST1E_RS03615	COG1965	Belongs to the frataxin family
ST1E_RS03620	COG0019	diaminopimelate decarboxylase activity
ST1E_RS03625	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ST1E_RS03635	COG0203	ribosomal protein L17
ST1E_RS03640	COG0202	RNA polymerase activity
ST1E_RS03645	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ST1E_RS03650	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ST1E_RS03655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ST1E_RS03660	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ST1E_RS03665	COG0201	protein transport
ST1E_RS03670	COG0200	Binds to the 23S rRNA
ST1E_RS03675	COG1841	ribosomal large subunit assembly
ST1E_RS03680	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ST1E_RS03685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ST1E_RS03695	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ST1E_RS03700	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ST1E_RS03705	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ST1E_RS03710	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ST1E_RS03715	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ST1E_RS03720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ST1E_RS03725	COG0255	Belongs to the universal ribosomal protein uL29 family
ST1E_RS03730	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ST1E_RS03735	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ST1E_RS03740	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ST1E_RS03745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ST1E_RS03750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ST1E_RS03755	COG0089	rRNA binding
ST1E_RS03765	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ST1E_RS03770	COG0051	transcription antitermination factor activity, RNA binding
ST1E_RS03780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ST1E_RS03785	COG0049	tRNA binding
ST1E_RS03790	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ST1E_RS03795	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ST1E_RS03800	COG0085	RNA polymerase activity
ST1E_RS03805	COG0222	ribosome binding
ST1E_RS03810	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ST1E_RS03815	COG0081	regulation of translation
ST1E_RS03820	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ST1E_RS03840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ST1E_RS03860	COG0357	Ribosomal RNA small subunit methyltransferase G
ST1E_RS03865	COG0445	tRNA wobble uridine modification
ST1E_RS03875	COG0706	membrane insertase activity
ST1E_RS03880	COG0594	ribonuclease P activity