locus-tag	class	description
CLIBASIA_RS00020	COG3617	BRO family, N-terminal domain
CLIBASIA_RS00045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLIBASIA_RS00050	COG0194	GDP metabolic process
CLIBASIA_RS00070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLIBASIA_RS00075	COG0280	phosphate acetyltransferase
CLIBASIA_RS00075	COG0281	malic enzyme
CLIBASIA_RS00080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CLIBASIA_RS00085	COG1127	ABC transporter
CLIBASIA_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLIBASIA_RS00105	COG0085	RNA polymerase activity
CLIBASIA_RS00135	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLIBASIA_RS00145	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLIBASIA_RS00155	COG0482	sulfurtransferase activity
CLIBASIA_RS00165	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CLIBASIA_RS00175	COG0483	inositol monophosphate 1-phosphatase activity
CLIBASIA_RS00180	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CLIBASIA_RS00185	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CLIBASIA_RS00210	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CLIBASIA_RS00220	COG0596	Alpha beta hydrolase
CLIBASIA_RS00235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLIBASIA_RS00240	COG4597	amino acid ABC transporter
CLIBASIA_RS00245	COG0765	amino acid transport
CLIBASIA_RS00250	COG1126	abc transporter atp-binding protein
CLIBASIA_RS00280	COG0321	lipoyl(octanoyl) transferase activity
CLIBASIA_RS00285	COG0343	queuine tRNA-ribosyltransferase activity
CLIBASIA_RS00295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CLIBASIA_RS00300	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CLIBASIA_RS00305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLIBASIA_RS00310	COG0629	single-stranded DNA binding
CLIBASIA_RS00315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CLIBASIA_RS00320	COG0174	glutamine synthetase
CLIBASIA_RS00325	COG2066	Belongs to the glutaminase family
CLIBASIA_RS00330	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CLIBASIA_RS00340	COG0114	fumarate hydratase activity
CLIBASIA_RS00345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLIBASIA_RS00350	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLIBASIA_RS00355	COG1132	(ABC) transporter
CLIBASIA_RS00360	COG0254	rRNA binding
CLIBASIA_RS00380	COG0504	CTP synthase activity
CLIBASIA_RS00390	COG0149	triose-phosphate isomerase activity
CLIBASIA_RS00405	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CLIBASIA_RS00415	COG0602	queuosine metabolic process
CLIBASIA_RS00430	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CLIBASIA_RS00435	COG0151	Belongs to the GarS family
CLIBASIA_RS00445	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CLIBASIA_RS00455	COG0321	lipoyl(octanoyl) transferase activity
CLIBASIA_RS00455	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CLIBASIA_RS00460	COG0084	hydrolase, TatD family'
CLIBASIA_RS00465	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLIBASIA_RS00470	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLIBASIA_RS00475	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLIBASIA_RS00495	COG0187	DNA topoisomerase II activity
CLIBASIA_RS00500	COG0628	permease
CLIBASIA_RS00510	COG0193	aminoacyl-tRNA hydrolase activity
CLIBASIA_RS00515	COG0012	GTP binding
CLIBASIA_RS00535	COG1872	DUF167
CLIBASIA_RS00540	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CLIBASIA_RS00545	COG1217	gtp-binding protein TYPA
CLIBASIA_RS00550	COG0137	argininosuccinate synthase activity
CLIBASIA_RS00560	COG0203	ribosomal protein L17
CLIBASIA_RS00565	COG0202	RNA polymerase activity
CLIBASIA_RS00570	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CLIBASIA_RS00575	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CLIBASIA_RS00580	COG0563	adenylate kinase activity
CLIBASIA_RS00585	COG0201	protein transport
CLIBASIA_RS00590	COG0200	Binds to the 23S rRNA
CLIBASIA_RS00595	COG1841	ribosomal large subunit assembly
CLIBASIA_RS00600	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CLIBASIA_RS00605	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CLIBASIA_RS00610	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLIBASIA_RS00615	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CLIBASIA_RS00620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CLIBASIA_RS00625	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CLIBASIA_RS00630	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CLIBASIA_RS00635	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CLIBASIA_RS00645	COG0255	Belongs to the universal ribosomal protein uL29 family
CLIBASIA_RS00650	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLIBASIA_RS00655	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CLIBASIA_RS00660	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CLIBASIA_RS00665	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLIBASIA_RS00670	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLIBASIA_RS00675	COG0089	rRNA binding
CLIBASIA_RS00680	COG0088	Forms part of the polypeptide exit tunnel
CLIBASIA_RS00685	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CLIBASIA_RS00690	COG0051	transcription antitermination factor activity, RNA binding
CLIBASIA_RS00695	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLIBASIA_RS00700	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLIBASIA_RS00705	COG0049	tRNA binding
CLIBASIA_RS00710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CLIBASIA_RS00725	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CLIBASIA_RS00730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLIBASIA_RS00735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CLIBASIA_RS00740	COG0740	serine-type endopeptidase activity
CLIBASIA_RS00760	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CLIBASIA_RS00765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLIBASIA_RS00770	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLIBASIA_RS00770	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLIBASIA_RS00775	COG0588	phosphoglycerate mutase activity
CLIBASIA_RS00780	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CLIBASIA_RS00785	COG0837	glucose binding
CLIBASIA_RS00790	COG1999	signal sequence binding
CLIBASIA_RS00795	COG0583	DNA-binding transcription factor activity
CLIBASIA_RS00800	COG0492	ferredoxin-NADP+ reductase activity
CLIBASIA_RS00810	COG0018	arginyl-trna synthetase
CLIBASIA_RS00815	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CLIBASIA_RS00820	COG0316	Belongs to the HesB IscA family
CLIBASIA_RS00825	COG0708	Exodeoxyribonuclease III
CLIBASIA_RS00830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLIBASIA_RS00845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CLIBASIA_RS00850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CLIBASIA_RS00855	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CLIBASIA_RS00860	COG0101	tRNA pseudouridine synthase activity
CLIBASIA_RS00865	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLIBASIA_RS00870	COG0242	peptide deformylase activity
CLIBASIA_RS00880	COG1960	acyl-CoA dehydrogenase activity
CLIBASIA_RS00885	COG0540	Belongs to the ATCase OTCase family
CLIBASIA_RS00890	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CLIBASIA_RS00895	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CLIBASIA_RS00910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLIBASIA_RS00915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLIBASIA_RS00955	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CLIBASIA_RS00970	COG0072	phenylalanine-tRNA ligase activity
CLIBASIA_RS00970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLIBASIA_RS00975	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CLIBASIA_RS00980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CLIBASIA_RS00985	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CLIBASIA_RS00990	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CLIBASIA_RS00995	COG0481	GTPase activity
CLIBASIA_RS01020	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CLIBASIA_RS01025	COG0653	protein targeting
CLIBASIA_RS01035	COG0360	Binds together with S18 to 16S ribosomal RNA
CLIBASIA_RS01040	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CLIBASIA_RS01045	COG0359	binds to the 23S rRNA
CLIBASIA_RS01050	COG0305	Participates in initiation and elongation during chromosome replication
CLIBASIA_RS01055	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLIBASIA_RS01070	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CLIBASIA_RS01090	COG4175	Glycine betaine
CLIBASIA_RS01090	COG3448	diguanylate cyclase activity
CLIBASIA_RS01105	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLIBASIA_RS01110	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CLIBASIA_RS01115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLIBASIA_RS01120	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CLIBASIA_RS01130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLIBASIA_RS01130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLIBASIA_RS01135	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLIBASIA_RS01150	COG0113	porphobilinogen synthase activity
CLIBASIA_RS01155	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLIBASIA_RS01175	COG0590	tRNA wobble adenosine to inosine editing
CLIBASIA_RS01180	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLIBASIA_RS01180	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLIBASIA_RS01185	COG0109	protoheme IX farnesyltransferase activity
CLIBASIA_RS01190	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CLIBASIA_RS01210	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CLIBASIA_RS01225	COG2086	electron transfer activity
CLIBASIA_RS01235	COG0165	Argininosuccinate lyase
CLIBASIA_RS01245	COG1338	Plays a role in the flagellum-specific transport system
CLIBASIA_RS01255	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CLIBASIA_RS01265	COG1706	bacterial-type flagellum-dependent cell motility
CLIBASIA_RS01270	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CLIBASIA_RS01275	COG4786	Flagellar basal body rod
CLIBASIA_RS01280	COG1677	Flagellar hook-basal body complex protein FliE
CLIBASIA_RS01285	COG1558	bacterial-type flagellum-dependent cell motility
CLIBASIA_RS01290	COG1815	bacterial-type flagellum-dependent cell motility
CLIBASIA_RS01295	COG0513	Belongs to the DEAD box helicase family
CLIBASIA_RS01310	COG1122	ATPase activity
CLIBASIA_RS01320	COG1301	dicarboxylic acid transport
CLIBASIA_RS01330	COG0105	UTP biosynthetic process
CLIBASIA_RS01340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CLIBASIA_RS01355	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CLIBASIA_RS01365	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CLIBASIA_RS01370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CLIBASIA_RS01375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CLIBASIA_RS01385	COG1663	tetraacyldisaccharide 4'-kinase activity
CLIBASIA_RS01390	COG1519	Transferase
CLIBASIA_RS01405	COG0742	ribosomal rna small subunit methyltransferase
CLIBASIA_RS01410	COG1187	pseudouridine synthase activity
CLIBASIA_RS01420	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLIBASIA_RS01430	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CLIBASIA_RS01445	COG2205	protein histidine kinase activity
CLIBASIA_RS01450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CLIBASIA_RS01450	COG0519	Catalyzes the synthesis of GMP from XMP
CLIBASIA_RS01455	COG1253	flavin adenine dinucleotide binding
CLIBASIA_RS01460	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CLIBASIA_RS01470	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CLIBASIA_RS01475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CLIBASIA_RS01480	COG0505	Belongs to the CarA family
CLIBASIA_RS01490	COG1160	GTP binding
CLIBASIA_RS01495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CLIBASIA_RS01500	COG1396	sequence-specific DNA binding
CLIBASIA_RS01505	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CLIBASIA_RS01515	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CLIBASIA_RS01520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLIBASIA_RS01525	COG1214	PFAM Peptidase M22, glycoprotease
CLIBASIA_RS01540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLIBASIA_RS01545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLIBASIA_RS01550	COG0167	dihydroorotate dehydrogenase activity
CLIBASIA_RS01555	COG1686	Belongs to the peptidase S11 family
CLIBASIA_RS01565	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CLIBASIA_RS01570	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CLIBASIA_RS01575	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CLIBASIA_RS01580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLIBASIA_RS01585	COG0438	transferase activity, transferring glycosyl groups
CLIBASIA_RS01590	COG0469	pyruvate kinase activity
CLIBASIA_RS01630	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CLIBASIA_RS01635	COG0670	Belongs to the BI1 family
CLIBASIA_RS01640	COG0284	orotidine-5'-phosphate decarboxylase activity
CLIBASIA_RS01650	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CLIBASIA_RS01660	COG0539	negative regulation of cytoplasmic translation
CLIBASIA_RS01665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CLIBASIA_RS01670	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CLIBASIA_RS01685	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLIBASIA_RS01695	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CLIBASIA_RS01705	COG0612	Peptidase, M16
CLIBASIA_RS01715	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CLIBASIA_RS01720	COG1722	exodeoxyribonuclease VII activity
CLIBASIA_RS01740	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CLIBASIA_RS01745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CLIBASIA_RS01750	COG1845	cytochrome c oxidase, subunit III
CLIBASIA_RS01755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CLIBASIA_RS01760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CLIBASIA_RS01770	COG0784	Response regulator, receiver
CLIBASIA_RS01790	COG0717	Belongs to the dCTP deaminase family
CLIBASIA_RS01795	COG0594	ribonuclease P activity
CLIBASIA_RS01800	COG0706	membrane insertase activity
CLIBASIA_RS01805	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CLIBASIA_RS01815	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CLIBASIA_RS01820	COG0156	8-amino-7-oxononanoate synthase activity
CLIBASIA_RS01825	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CLIBASIA_RS01830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLIBASIA_RS01880	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CLIBASIA_RS01885	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CLIBASIA_RS01890	COG1072	(Pantothenic acid kinase))
CLIBASIA_RS01895	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CLIBASIA_RS01900	COG2205	protein histidine kinase activity
CLIBASIA_RS01910	COG2887	Belongs to the helicase family. UvrD subfamily
CLIBASIA_RS01930	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CLIBASIA_RS01935	COG0237	dephospho-CoA kinase activity
CLIBASIA_RS01940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLIBASIA_RS01945	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CLIBASIA_RS01965	COG0424	maF-like protein
CLIBASIA_RS01970	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CLIBASIA_RS01975	COG1981	membrane
CLIBASIA_RS01980	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CLIBASIA_RS01985	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CLIBASIA_RS01990	COG0445	tRNA wobble uridine modification
CLIBASIA_RS02020	COG0495	leucyl-tRNA aminoacylation
CLIBASIA_RS02025	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLIBASIA_RS02035	COG1674	ftsk spoiiie
CLIBASIA_RS02055	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CLIBASIA_RS02060	COG0180	Tryptophanyl-tRNA synthetase
CLIBASIA_RS02070	COG2309	aminopeptidase activity
CLIBASIA_RS02075	COG1570	exodeoxyribonuclease VII activity
CLIBASIA_RS02085	COG0779	Required for maturation of 30S ribosomal subunits
CLIBASIA_RS02095	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CLIBASIA_RS02100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CLIBASIA_RS02105	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CLIBASIA_RS02110	COG1185	polyribonucleotide nucleotidyltransferase activity
CLIBASIA_RS02115	COG4957	zinc ion binding
CLIBASIA_RS02125	COG2171	N-acyltransferase activity
CLIBASIA_RS02130	COG0537	adenosine 5'-monophosphoramidase activity
CLIBASIA_RS02135	COG0052	Belongs to the universal ribosomal protein uS2 family
CLIBASIA_RS02140	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CLIBASIA_RS02145	COG0528	UMP kinase activity
CLIBASIA_RS02150	COG0233	cytoplasmic translational termination
CLIBASIA_RS02155	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CLIBASIA_RS02165	COG0750	zinc metalloprotease
CLIBASIA_RS02170	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLIBASIA_RS02175	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLIBASIA_RS02180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLIBASIA_RS02185	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLIBASIA_RS02195	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLIBASIA_RS02200	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLIBASIA_RS02205	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CLIBASIA_RS02225	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CLIBASIA_RS02230	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CLIBASIA_RS02240	COG0277	FAD linked oxidase domain protein
CLIBASIA_RS02245	COG0009	L-threonylcarbamoyladenylate synthase
CLIBASIA_RS02260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLIBASIA_RS02265	COG0752	glycyl-tRNA synthetase alpha subunit
CLIBASIA_RS02275	COG0142	geranyltranstransferase activity
CLIBASIA_RS02280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLIBASIA_RS02295	COG1530	ribonuclease E activity
CLIBASIA_RS02300	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLIBASIA_RS02305	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CLIBASIA_RS02310	COG0776	regulation of translation
CLIBASIA_RS02315	COG0616	signal peptide processing
CLIBASIA_RS02330	COG1137	ATPase activity
CLIBASIA_RS02335	COG1573	uracil-dna glycosylase
CLIBASIA_RS02345	COG0019	diaminopimelate decarboxylase activity
CLIBASIA_RS02355	COG2835	tetraacyldisaccharide 4'-kinase activity
CLIBASIA_RS02405	COG4964	Belongs to the GSP D family
CLIBASIA_RS02435	COG1528	Iron-storage protein
CLIBASIA_RS02440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLIBASIA_RS02445	COG1121	(ABC) transporter
CLIBASIA_RS02455	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CLIBASIA_RS02460	COG0335	large ribosomal subunit rRNA binding
CLIBASIA_RS02465	COG0336	Belongs to the RNA methyltransferase TrmD family
CLIBASIA_RS02470	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CLIBASIA_RS02475	COG0228	four-way junction DNA binding
CLIBASIA_RS02480	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLIBASIA_RS02485	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CLIBASIA_RS02490	COG0552	protein localization to endoplasmic reticulum
CLIBASIA_RS02510	COG0573	inorganic phosphate transmembrane transporter activity
CLIBASIA_RS02520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLIBASIA_RS02525	COG0704	Plays a role in the regulation of phosphate uptake
CLIBASIA_RS02530	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CLIBASIA_RS02540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLIBASIA_RS02550	COG1686	Belongs to the peptidase S11 family
CLIBASIA_RS02555	COG1970	mechanosensitive ion channel activity
CLIBASIA_RS02560	COG0189	ligase activity
CLIBASIA_RS02565	COG1766	The M ring may be actively involved in energy transduction
CLIBASIA_RS02570	COG2771	luxR family
CLIBASIA_RS02575	COG2197	response regulator
CLIBASIA_RS02585	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLIBASIA_RS02590	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLIBASIA_RS02595	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLIBASIA_RS02600	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLIBASIA_RS02605	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CLIBASIA_RS02610	COG4786	Flagellar basal body rod
CLIBASIA_RS02615	COG1157	protein secretion by the type III secretion system
CLIBASIA_RS02620	COG0739	heme binding
CLIBASIA_RS02630	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CLIBASIA_RS02635	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CLIBASIA_RS02655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CLIBASIA_RS02660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLIBASIA_RS02665	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLIBASIA_RS02670	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLIBASIA_RS02670	COG0022	dehydrogenase e1 component
CLIBASIA_RS02675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CLIBASIA_RS02685	COG0148	phosphopyruvate hydratase activity
CLIBASIA_RS02690	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CLIBASIA_RS02700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLIBASIA_RS02700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLIBASIA_RS02705	COG0138	bifunctional purine biosynthesis protein purh
CLIBASIA_RS02710	COG0288	reversible hydration of carbon dioxide
CLIBASIA_RS02715	COG2902	Dehydrogenase
CLIBASIA_RS02720	COG2925	Exonuclease
CLIBASIA_RS02730	COG0217	transcriptional regulatory protein
CLIBASIA_RS02735	COG1692	metallophosphoesterase
CLIBASIA_RS02755	COG0126	phosphoglycerate kinase activity
CLIBASIA_RS02760	COG3588	fructose-bisphosphate aldolase
CLIBASIA_RS02775	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CLIBASIA_RS02780	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLIBASIA_RS02785	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CLIBASIA_RS02790	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CLIBASIA_RS02825	COG0419	ATPase involved in DNA repair
CLIBASIA_RS02830	COG0484	heat shock protein binding
CLIBASIA_RS02835	COG0443	Heat shock 70 kDa protein
CLIBASIA_RS02875	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CLIBASIA_RS02880	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CLIBASIA_RS02885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLIBASIA_RS02890	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CLIBASIA_RS02895	COG0268	Binds directly to 16S ribosomal RNA
CLIBASIA_RS02900	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CLIBASIA_RS02905	COG2226	methyltransferase
CLIBASIA_RS02910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CLIBASIA_RS02915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLIBASIA_RS02920	COG0071	Belongs to the small heat shock protein (HSP20) family
CLIBASIA_RS02925	COG1959	2 iron, 2 sulfur cluster binding
CLIBASIA_RS02935	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLIBASIA_RS02940	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLIBASIA_RS02945	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLIBASIA_RS02950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CLIBASIA_RS02955	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CLIBASIA_RS02965	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLIBASIA_RS02975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLIBASIA_RS02980	COG0564	pseudouridine synthase activity
CLIBASIA_RS02990	COG0564	pseudouridine synthase activity
CLIBASIA_RS03005	COG0006	proline dipeptidase activity
CLIBASIA_RS03010	COG0156	8-amino-7-oxononanoate synthase activity
CLIBASIA_RS03015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLIBASIA_RS03030	COG0436	Aminotransferase
CLIBASIA_RS03035	COG0513	Belongs to the DEAD box helicase family
CLIBASIA_RS03040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLIBASIA_RS03045	COG0322	excinuclease ABC activity
CLIBASIA_RS03060	COG1116	anion transmembrane transporter activity
CLIBASIA_RS03075	COG1968	undecaprenyl-diphosphatase activity
CLIBASIA_RS03085	COG0354	folic acid binding
CLIBASIA_RS03100	COG0825	malonyl-CoA metabolic process
CLIBASIA_RS03105	COG4974	Belongs to the 'phage' integrase family
CLIBASIA_RS03120	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CLIBASIA_RS03125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLIBASIA_RS03150	COG0688	phosphatidylethanolamine metabolic process
CLIBASIA_RS03155	COG5265	(ABC) transporter
CLIBASIA_RS03170	COG0215	cysteine-tRNA ligase activity
CLIBASIA_RS03185	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLIBASIA_RS03190	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CLIBASIA_RS03225	COG4143	(ABC) transporter
CLIBASIA_RS03230	COG1178	ABC-type Fe3 transport system permease component
CLIBASIA_RS03235	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CLIBASIA_RS03245	COG0494	nUDIX hydrolase
CLIBASIA_RS03260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CLIBASIA_RS03265	COG0632	four-way junction helicase activity
CLIBASIA_RS03270	COG2255	four-way junction helicase activity
CLIBASIA_RS03295	COG2885	chlorophyll binding
CLIBASIA_RS03300	COG0037	tRNA processing
CLIBASIA_RS03305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLIBASIA_RS03310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLIBASIA_RS03325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLIBASIA_RS03330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLIBASIA_RS03335	COG1121	(ABC) transporter
CLIBASIA_RS03340	COG0803	Belongs to the bacterial solute-binding protein 9 family
CLIBASIA_RS03345	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CLIBASIA_RS03355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLIBASIA_RS03360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLIBASIA_RS03365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CLIBASIA_RS03385	COG1360	Flagellar Motor Protein
CLIBASIA_RS03425	COG5443	negative regulation of bacterial-type flagellum assembly
CLIBASIA_RS03435	COG4794	Type iii secretion
CLIBASIA_RS03460	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLIBASIA_RS03490	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CLIBASIA_RS03495	COG0363	glucosamine-6-phosphate deaminase activity
CLIBASIA_RS03500	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CLIBASIA_RS03510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLIBASIA_RS03510	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CLIBASIA_RS03525	COG0416	fatty acid biosynthetic process
CLIBASIA_RS03530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLIBASIA_RS03535	COG0776	regulation of translation
CLIBASIA_RS03540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CLIBASIA_RS03555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CLIBASIA_RS03590	COG0489	protein tyrosine kinase activity
CLIBASIA_RS03595	COG3158	transport of potassium into the cell
CLIBASIA_RS03610	COG0358	DNA primase activity
CLIBASIA_RS03615	COG0517	IMP dehydrogenase activity
CLIBASIA_RS03615	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CLIBASIA_RS03620	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CLIBASIA_RS03645	COG1183	phosphatidylcholine synthase activity
CLIBASIA_RS03650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLIBASIA_RS03670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLIBASIA_RS03675	COG0196	riboflavin kinase activity
CLIBASIA_RS03685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CLIBASIA_RS03690	COG0459	protein refolding
CLIBASIA_RS03705	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLIBASIA_RS03710	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLIBASIA_RS03715	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLIBASIA_RS03720	COG0649	NAD binding
CLIBASIA_RS03725	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CLIBASIA_RS03730	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CLIBASIA_RS03740	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CLIBASIA_RS03745	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLIBASIA_RS03770	COG1007	ATP synthesis coupled electron transport
CLIBASIA_RS03785	COG0442	prolyl-tRNA aminoacylation
CLIBASIA_RS03795	COG1136	(ABC) transporter
CLIBASIA_RS03800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLIBASIA_RS03805	COG0527	aspartate kinase activity
CLIBASIA_RS03810	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLIBASIA_RS03815	COG2890	protein-(glutamine-N5) methyltransferase activity
CLIBASIA_RS03825	COG0542	response to heat
CLIBASIA_RS03830	COG0739	heme binding
CLIBASIA_RS03870	COG4974	Belongs to the 'phage' integrase family
CLIBASIA_RS03875	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CLIBASIA_RS03880	COG0302	gtp cyclohydrolase
CLIBASIA_RS03920	COG0745	RESPONSE REGULATOR receiver
CLIBASIA_RS03940	COG0544	peptidyl-prolyl cis-trans isomerase activity
CLIBASIA_RS03955	COG0024	Methionine aminopeptidase
CLIBASIA_RS03970	COG0538	isocitrate dehydrogenase activity
CLIBASIA_RS03975	COG2202	Pas domain
CLIBASIA_RS03975	COG2205	protein histidine kinase activity
CLIBASIA_RS03980	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CLIBASIA_RS03985	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CLIBASIA_RS04005	COG0194	GDP metabolic process
CLIBASIA_RS04020	COG1278	Cold shock
CLIBASIA_RS04035	COG2204	response regulator
CLIBASIA_RS04040	COG1132	(ABC) transporter
CLIBASIA_RS04045	COG1216	Glycosyl transferase, family 2
CLIBASIA_RS04045	COG0438	transferase activity, transferring glycosyl groups
CLIBASIA_RS04050	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CLIBASIA_RS04055	COG1088	dTDP-glucose 4,6-dehydratase activity
CLIBASIA_RS04060	COG1091	dTDP-4-dehydrorhamnose reductase activity
CLIBASIA_RS04065	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CLIBASIA_RS04075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLIBASIA_RS04075	COG4651	solute:proton antiporter activity
CLIBASIA_RS04080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLIBASIA_RS04090	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLIBASIA_RS04095	COG0124	histidyl-tRNA synthetase
CLIBASIA_RS04120	COG0525	valine-tRNA ligase activity
CLIBASIA_RS04140	COG1758	RNA polymerase activity
CLIBASIA_RS04145	COG0736	holo-[acyl-carrier-protein] synthase activity
CLIBASIA_RS04150	COG0681	Belongs to the peptidase S26 family
CLIBASIA_RS04155	COG0571	ribonuclease III activity
CLIBASIA_RS04160	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CLIBASIA_RS04165	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLIBASIA_RS04170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CLIBASIA_RS04190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLIBASIA_RS04195	COG1381	Involved in DNA repair and RecF pathway recombination
CLIBASIA_RS04200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLIBASIA_RS04210	COG0210	DNA helicase
CLIBASIA_RS04230	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLIBASIA_RS04240	COG0330	HflC and HflK could
CLIBASIA_RS04245	COG0330	HflC and HflK could
CLIBASIA_RS04250	COG0560	Phosphoserine phosphatase
CLIBASIA_RS04270	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLIBASIA_RS04280	COG2814	Major facilitator Superfamily
CLIBASIA_RS04285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CLIBASIA_RS04290	COG0271	Belongs to the BolA IbaG family
CLIBASIA_RS04295	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLIBASIA_RS04300	COG0047	phosphoribosylformylglycinamidine synthase activity
CLIBASIA_RS04305	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLIBASIA_RS04310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CLIBASIA_RS04315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CLIBASIA_RS04320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CLIBASIA_RS04325	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLIBASIA_RS04330	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLIBASIA_RS04335	COG0154	amidase activity
CLIBASIA_RS04340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLIBASIA_RS04355	COG1280	lysine exporter protein (LysE YggA)
CLIBASIA_RS04390	COG0556	nucleotide-excision repair
CLIBASIA_RS04395	COG1607	acyl-coa hydrolase
CLIBASIA_RS04400	COG0730	response to heat
CLIBASIA_RS04425	COG2166	iron-sulfur cluster assembly
CLIBASIA_RS04435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLIBASIA_RS04455	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLIBASIA_RS04465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLIBASIA_RS04495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CLIBASIA_RS04500	COG0418	dihydroorotase activity
CLIBASIA_RS04535	COG3425	synthase
CLIBASIA_RS04540	COG1304	FMN binding
CLIBASIA_RS04550	COG1988	membrane-bound metal-dependent
CLIBASIA_RS04560	COG0756	dUTP diphosphatase activity
CLIBASIA_RS04585	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CLIBASIA_RS04590	COG0720	synthase
CLIBASIA_RS04615	COG0181	hydroxymethylbilane synthase activity
CLIBASIA_RS04620	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CLIBASIA_RS04625	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CLIBASIA_RS04660	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CLIBASIA_RS04665	COG0039	L-malate dehydrogenase activity
CLIBASIA_RS04670	COG0045	succinate-CoA ligase (ADP-forming) activity
CLIBASIA_RS04675	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CLIBASIA_RS04680	COG0567	Dehydrogenase, E1 component
CLIBASIA_RS04685	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLIBASIA_RS04695	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CLIBASIA_RS04715	COG0719	Fe-S assembly protein
CLIBASIA_RS04720	COG0396	ATPase activity
CLIBASIA_RS04725	COG0719	Fe-S assembly protein
CLIBASIA_RS04730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLIBASIA_RS04735	COG2151	metal-sulfur cluster biosynthetic enzyme
CLIBASIA_RS04740	COG0316	Belongs to the HesB IscA family
CLIBASIA_RS04745	COG1509	lysine 2,3-aminomutase activity
CLIBASIA_RS04755	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLIBASIA_RS04775	COG0408	coproporphyrinogen oxidase activity
CLIBASIA_RS04780	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CLIBASIA_RS04790	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLIBASIA_RS04810	COG3750	Belongs to the UPF0335 family
CLIBASIA_RS04835	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CLIBASIA_RS04840	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CLIBASIA_RS04845	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLIBASIA_RS04850	COG0356	it plays a direct role in the translocation of protons across the membrane
CLIBASIA_RS04865	COG1104	cysteine desulfurase activity
CLIBASIA_RS04870	COG2945	thiolester hydrolase activity
CLIBASIA_RS04875	COG0751	glycine-tRNA ligase activity
CLIBASIA_RS04885	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CLIBASIA_RS04890	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLIBASIA_RS04895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLIBASIA_RS04905	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLIBASIA_RS04910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLIBASIA_RS04920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLIBASIA_RS04930	COG5462	secreted (periplasmic) protein
CLIBASIA_RS04935	COG0275	rRNA processing
CLIBASIA_RS04940	COG2001	Belongs to the MraZ family
CLIBASIA_RS04945	COG0033	Phosphoglucomutase
CLIBASIA_RS04970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLIBASIA_RS04975	COG0765	amino acid transport
CLIBASIA_RS04985	COG0617	tRNA 3'-terminal CCA addition
CLIBASIA_RS04990	COG1862	Preprotein translocase
CLIBASIA_RS04995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLIBASIA_RS05000	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CLIBASIA_RS05010	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CLIBASIA_RS05025	COG0488	(ABC) transporter
CLIBASIA_RS05145	COG0305	Participates in initiation and elongation during chromosome replication
CLIBASIA_RS05185	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CLIBASIA_RS05210	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CLIBASIA_RS05215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLIBASIA_RS05230	COG1823	symporter activity
CLIBASIA_RS05235	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLIBASIA_RS05245	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLIBASIA_RS05255	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLIBASIA_RS05260	COG0849	cell division
CLIBASIA_RS05265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CLIBASIA_RS05270	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLIBASIA_RS05345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLIBASIA_RS05350	COG0194	GDP metabolic process